LOCUS       DBNFCO010000001        81494 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.001, whole genome shotgun sequence.
ACCESSION   DBNFCO010000001 DBNFCO010000000
VERSION     DBNFCO010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 81494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 81494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..81494
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.001"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            60..1649
                     /locus_tag="AC1PIV_000001"
     CDS             60..1649
                     /locus_tag="AC1PIV_000001"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0009007 - site-specific
                     DNA-methyltransferase (adenine-specific) activity
                     [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HIP6611064.1"
                     /translation="MSKTIQAITNQIWSMANELRGNMDASEYKNYILAFMFYRYLSEH
                     QERFLVEDEIISPAPGETVQDAYAREAVGNDLVEHLENTASHLGYAIEPEDTWARLVA
                     KIDNSEIVASDYQTIFDHFNANVELNRDAMEDFRGVFNDINLGDSRLGNSTVVRAKSL
                     NSIVKLIDSIEYKNDEGKDILGEIYEYLIGQFAASAGKKGGEFYTPHQVSKILAKIVT
                     LGLEKSDTSFSVYDPTMGSGSLLLTVRNELPQGQHIKFYGQEMNTTTYNLARMNLMMH
                     QVGYSNMILNNADTLESDWPDGVDELGIDQPRSFDAVVANPPYSAKWDNRESKLKDPR
                     FMEYGKLAPASKADFAFILHSLYHLNNTGTMAIVLPHGVLFRGAAEGHIRKLIIEKNY
                     LDAVIGLPANLFYGTGIPTTILVFKKNRQTKDVFFIDASKEFEKGKNQNHLSDDMVEK
                     IVETYHNRQSVDKYAHLASIEEIVENDYNLNIPRYVDTFEEEEEIDLGQVTQQLEQDR
                     LEIRALEDKIRQQLKTLGVDF"
     gene            complement(1700..2974)
                     /gene="serS"
                     /locus_tag="AC1PIV_000002"
     CDS             complement(1700..2974)
                     /gene="serS"
                     /locus_tag="AC1PIV_000002"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HIP6611065.1"
                     /translation="MLDIKRIRTDFDGVAAKLATRGVAAETLANIKELDAKRREILVT
                     VEELKAERNTVSAEIAQAKRNKENADDKIAAMQKLSADVKNLDAQLLEIDEELNAIIT
                     VLPNTPHDSVPVGADEEENVEVRRWGTPREFTFEPKAHWDLGEDLDILDWERGAKVTG
                     ARFLFYKNLGARLERALYNFMLDEHIAEGYQEIITPYMVNHDSMFGTGQYPKFKEDTF
                     ELADTNFVLIPTAEVPLTNYYRNEILEEKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFATPEQSYDELEKMTANAENILQKLGLPYRVLALCTGDMGFSAAKTY
                     DLEVWIPAQNAYREISSCSNTEDFQARRAQIRYRDAADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEVLRPYMGGVEVIKP"
     gene            complement(3192..3563)
                     /locus_tag="AC1PIV_000003"
     CDS             complement(3192..3563)
                     /locus_tag="AC1PIV_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HIP6611066.1"
                     /translation="MAQSQNTSVELQTTGVSYMGFGGKVGKFLIGDKALEFYPDSNVE
                     RYIQIPWSEMTSIGANVSGKAISRHFEIYTEKSRFLFASKDSGKILKIAREHIGNEKV
                     VKLPTLMQTIGRKISNLFAKK"
     gene            complement(3623..4534)
                     /locus_tag="AC1PIV_000004"
     CDS             complement(3623..4534)
                     /locus_tag="AC1PIV_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HIP6611067.1"
                     /translation="MSEKIQLSVSDRKKVWWRSTFLQGSWNYERMQNLGWAYAMIPAI
                     KKLYTKKEDQAAALERHLEFFNTHPYVASPILGVTLALEEERANGAEIDDTAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGALGASLALSGNIMGPIIFFLGWNIIRMAFLWYTQE
                     FGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVSITFAVDLPAKQLSEGA
                     YIVFPEGTVTGAELKGILGQALSGLSLEPTQAQTLQGQLDSLIPGLMGLLLTFLCMHL
                     LKKKVTPITMIIGLFIVGILARFFGIM"
     gene            complement(4552..5361)
                     /locus_tag="AC1PIV_000005"
     CDS             complement(4552..5361)
                     /locus_tag="AC1PIV_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HIP6611068.1"
                     /translation="MSDITLISAILVVIVAFFAGLEGILDEFQFHQPLVACTLIGLVT
                     GNLAAGVMLGGSLQMIALGWANIGAAVAPDAALASVAAAIIMIKGGDFSTEGIAVATT
                     TAIPLAVAGLFLTMIVRTISVGLVHGADNAAKDANFAAVERYHLFALLLQGLRIAVPA
                     ALLLAIPAEAVQAVLESMPAWLSGGMAVGGGMVVAVGYAMVINMMATREVWPFFALGF
                     AFAAISKLTLIALGVIGVAIALIYLNLSKQGGSGNGGASSNDPIGDILEDY"
     gene            complement(5393..6385)
                     /locus_tag="AC1PIV_000006"
     CDS             complement(5393..6385)
                     /locus_tag="AC1PIV_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HIP6611069.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPSEGPDD
                     LYAKLNAAVDAFDADDEVLVLADLWSGSPFNQASRVAGENPDRKFAIITGLNLPMLIQ
                     AYTERMINAAAGVEEVAANIIKEAKDGIKVLPEELQPAEAAPVADAAPVALQGAIPPG
                     TVIGDGKLKINLARIDTRLLHGQVATGWTPASKADRIIVASDTVAKDELRKQLIKQAA
                     PGNVKANVVPIKKLIEVSKDPRFGNTHALILFETPQEALEAIEGGVEIKELNVGSMAH
                     STGKTMVNNVLSMDKDDVATFEKLRDLGVEFDVRKVPNDSKKDLFELINKANVQ"
     gene            complement(6607..7419)
                     /locus_tag="AC1PIV_000007"
     CDS             complement(6607..7419)
                     /locus_tag="AC1PIV_000007"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HIP6611070.1"
                     /translation="MKKKIIAIDLDGTLLNNDSQLSDYTISTIKKVRQAGHTVLIATG
                     RPYRMAEKFYQQLELDTPMINFNGSLVHIPGKKWQWEQNILIDKKYLLEFLKEEETFE
                     ADFIAGEYKNKFYITQKNLDKIDPALMGVEQITPDTLIKPELITSDPHSILMQTRATD
                     KYELAKEMNAYFKDELEINTWGGPLNILETCAKGVNKATALSYVLNLYQASPSDLIAF
                     GDEHNDVEMLDLAGTAYAMKNCSDTLRPHADRLTAFANFEDGVARELENLFL"
     gene            7764..9224
                     /locus_tag="AC1PIV_000008"
     CDS             7764..9224
                     /locus_tag="AC1PIV_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015851 - nucleobase transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HIP6611071.1"
                     /translation="MDQFFKLKEHGTTVSTEIMAGLTTFFAMSYILFVNPSVLSVAGM
                     PTQAVFLATIIASAVSTLVMGLFANVPYALAPGMGLNAFFTYTVVIGLGFTWQEALAM
                     VFLCGLFNVFITVTKVRKSIIKAIPVSLQHAIGGGIGVFVAYLGFKNSNLITFLTSGS
                     DIITVNGVAPADATAETFSNGVFSVFAGGGVVPGISTFTDPSVLLTVFGLLLTAVLVI
                     KNVRGAILIGIIATTVAGIPAGVVDLSTIDFANNNTGTAFAELGTTFLAAFDGLSSLF
                     ADSSRLPLVLMTIFAFSLSDTFDTLGTFIGTGRKTGIFSEEDEKALENGTGFNSKMDK
                     ALFADAIGTSIGALFGTSNTTTYVESAAGISAGGRTGLTAVTTAVLFLLSILILPFIG
                     IVPNAATAPALIIIGVMMVSSFLDVDWSHFEDALPAFFAAFFMALCFSISYGIAAAFI
                     FYCLVKVSTGKAKEIHPILWGATALFILNFIILAIL"
     gene            complement(9573..10433)
                     /gene="metF"
                     /locus_tag="AC1PIV_000009"
     CDS             complement(9573..10433)
                     /gene="metF"
                     /locus_tag="AC1PIV_000009"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HIP6611072.1"
                     /translation="MIGQTPSLSFEIFPPKPAVGNEKIIQTLDEMQGLAPHFISVTCS
                     NNNLNVEETTVKLANHVRNELHIPTIAHLPAAYLTKEKVRSVLHSLDEIGVHQILALR
                     GDIIEGLPPKEDFQYATDLISFIKEEAPHFDIIGACYPEVHPESPNSVSDIKNLKKKV
                     DAGCSTLVTQLFFDNEAFYNFQEKCSLADIEVPIIAGIMPIINKNQALRLLKTCENIR
                     LPRKFKAILEKYEHNPESLRAAGLAYAVDQIVDLVTNDVAGIHLYTMNNAETARTIHQ
                     ATHSLFKHYS"
     gene            complement(10437..12686)
                     /gene="metE"
                     /locus_tag="AC1PIV_000010"
     CDS             complement(10437..12686)
                     /gene="metE"
                     /locus_tag="AC1PIV_000010"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003871 -
                     5-methyltetrahydropteroyltriglutamate-homocysteine
                     S-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HIP6611073.1"
                     /translation="MTTTIIGFPRIGEHRELKFITEKYFRNEIPQEELLEAAKDLRAK
                     HWNIVKEAGITEIPSNDFSHYDNVLDAAVLFNIIPKAVQDLELTDLEKYFALARGYQG
                     EKGDVRARPMKKWFNTNYHYIVPAIEKDTEIKLAGHKIFDEFQEAKNLGITTRPVLIG
                     PFTLLQLTDFEEGLTATNFADSLVAAYGQVFEKLAELGAEKIQLDEPSLVKDLTAEEK
                     ALFLRIYQTLLADKKGLQVLIQTYFGDVRDIYTELTSLPVDAIGLDFVEGKETAALVA
                     TGFPADKTLYAGIVNGKNIWRNNYEKSLAVLDAIPAENVVITTSCSLLHVPFTTANEE
                     FEPAILNHFAFAVEKLSELRDLDAIRNGQGEVALTANKELFALERVGRDAALADRLAG
                     LTDTDYTRLPVFAERESIQREKLNLPLLPTTTIGSFPQTKEVRSTRLAFRKGNISEEE
                     YDAFVKTQTDEWIAWQEEVDFDVLVHGEFERNDMVEYFGENLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKE
                     STLQIALAIKEEVLDLEAAGIKIIQIDEAALREKLPLRRSDWYSEYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLVILDELKAKNFQTQVG
                     PGVYDIHSPRVPAVDEIAHTIQAILAKVPKEKVWINPDCGLKTRGESETKASLIHLTQ
                     AAKAARKEL"
     gene            13067..13756
                     /locus_tag="AC1PIV_000011"
     CDS             13067..13756
                     /locus_tag="AC1PIV_000011"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0016811 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds, in linear amides
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HIP6611074.1"
                     /translation="MGKVIIGISGNEQEFPTKSGRVYVTVARELADSVRQAGGVPMVI
                     PMGTPDLAKDYIDMIDKLILSGGQHVDPSLYGQKRLIDSNDYLLERDEFELALIEEAL
                     HQGKPIFAVCRGMQLLNVALGGSLEQEVDHHWQDGIAGTSHRLQVKPKSRIGQLFAQG
                     SPINSFHQQRIKELAPGLVATGLDPRDGTIEAYESRGNQALFGIQWHPEFLYNDCKQH
                     RDLFQYLVDIF"
     gene            13906..14757
                     /locus_tag="AC1PIV_000012"
     CDS             13906..14757
                     /locus_tag="AC1PIV_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HIP6611075.1"
                     /translation="MKLKKLFSLATAALSVGVLAACGNSSSSSDSSATTVRVGVMSLS
                     DSEQARWDKVQEILGDEVKLEFTQFTDYSQPNKAVAENEVDINAFQHYNFLNNWNQEN
                     GEDLVAIADTYIAPIRLYSGTADGKNKYTKVEEIPDGAEIAVPNDPTNESRALYLLQA
                     AGLIKVGVSGTELATIADITENKKNLKITELDASQTASSLSSVDAAVVNNTFVLEAGL
                     DYKNALYKEQKDENSKQWYNLIAARSDWEKSEQAAAIKKIIEAYHTDEVKKVIEETSD
                     GMDEPVW"
     gene            14914..16281
                     /locus_tag="AC1PIV_000013"
     CDS             14914..16281
                     /locus_tag="AC1PIV_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HIP6611076.1"
                     /translation="MADSKVQAFENDAIIQTYFEKLKVLISKKSIFAQQIGLLDVATY
                     LKDIFEEAGAEVVLDDSYAAPFVMARFEASVPDAKTLIFYNHYDTVPADADQVWEKGN
                     PFELTISDGYIYGRGVDDDKGHITARLSALKKYQARQNGHLPVNVIFIMEGAEESASV
                     DLDKYLSKYKEHLIGADLLVWEQGHRNSLHQLEIAGGNKGIVTFDLQVKSADLDIHSS
                     YGGVIDSASWYLLSALQSMRAADGQILVEGIYDQVQEPNERELALVEEFALATSQSMT
                     DIYGLTLPTLIEDRREFLKRLYFEPSITIQGLSTGYLGQGVKTIIPAQASAKMEVRLV
                     PGLEPHDVLDKIRQHLDKHGFDKVEVVFTLGEMSYRSDMSHPAIVNVIELAKKLTPEG
                     VAVLPTSPGTGPMHTVFHALGVPIAGFGLGNANSRDHAGDENVSIADYYSHVELVEEL
                     IASYE"
     gene            16274..17338
                     /locus_tag="AC1PIV_000014"
     CDS             16274..17338
                     /locus_tag="AC1PIV_000014"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HIP6611077.1"
                     /translation="MSKEMIKLDNIDVTFQQKKRTIEAVKDVTIHINQGDIYGIVGYS
                     GAGKSTLVRVINLLQVPTAGKITIDEDVIYEGEKVTLTPAQLRSKRREIGMIFQHFNL
                     MAQMTAEENVAFALKHSGLSKEEKKEKVAKLLDLVGLSDRAENYPAQLSGGQKQRVAI
                     ARALANDPKILISDESTSALDPKTTKQILALLQELNEKLGLTIVMITHEMQIVKDICN
                     RVAVMQDGRLIEEGSVLEIFSHPKEELTQDFIKTATGIDEALVKIYQQDIVKNLPENS
                     ILVQLKYAGSNTDTAIVNDLYKFYQVSANILYGNIEILDHTPVGEMVVILSGEPGQLH
                     RAIEAVTEARVEVTILKGAN"
     gene            17339..18031
                     /locus_tag="AC1PIV_000015"
     CDS             17339..18031
                     /locus_tag="AC1PIV_000015"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HIP6611078.1"
                     /translation="MLEWIQTNFPDIYKLGWDGQTGWLTHFNLTLYMTFVSFAFGGFM
                     GLVSGLFLVLTGPRGVIANKTAYWILDKVASIFRAIPFIILLAAIAPLTKIIVGKTIG
                     TEAALVPLALSVFPFFARQVEVVLSELDRGVIEAAQASGATFWDIVLVYLREGLPDLI
                     RVTTFALVSLVGYTAMAGAIGAGGLGQVALSYGYLRYNNDVTFLATLLILVIIFVIQF
                     IGDFLTRKISHR"
     gene            18213..18917
                     /locus_tag="AC1PIV_000016"
     CDS             18213..18917
                     /locus_tag="AC1PIV_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="B3/B4 domain-containing protein"
                     /protein_id="HIP6611079.1"
                     /translation="MSQFVVDSSFWSLFPDAKIGVLLLKDYKTPAQSPDELVKLLEES
                     NGIAQKFLTEDTFSENEVIRTYRQAYQKFKTKKGARSSIEALLKRSTSDRPVTTISPL
                     VDIYNAASLRFGLPCGAEDLDTFVGNLQLTVTEGGDEFYLIGDETNNPTLPGEVCYKD
                     DKGAVCRCFNWRDGERTMITDETKNAFLVMELVNSDRVEDLENALDFISQHAEKFLGV
                     VPEKYLLDCDRPAIAL"
     gene            19268..19663
                     /locus_tag="AC1PIV_000017"
     CDS             19268..19663
                     /locus_tag="AC1PIV_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1398 domain-containing protein"
                     /protein_id="HIP6611080.1"
                     /translation="MFTLENINHGHEQFTGPDFPKLIAYFKDLGMVENIVDIQSGQVT
                     YRSQTGQTLEKQGYQVTIPVSDQANLDQFVTILRNHQAGQTDFLTFCQETAEAGIYKW
                     VIDLEAMTCSYMDKAEQAVFVETIPSVEN"
     gene            19974..20891
                     /gene="glyQ"
                     /locus_tag="AC1PIV_000018"
     CDS             19974..20891
                     /gene="glyQ"
                     /locus_tag="AC1PIV_000018"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HIP6611081.1"
                     /translation="MSKKLTFQEIILTLQQFWNEQGCLLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLER
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEVSDQDMLLENFT
                     KFEKEAERALEEGLVHPAFDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKKLGFPLLDEATRAELLKEDAE"
     gene            20891..22927
                     /gene="glyS"
                     /locus_tag="AC1PIV_000019"
     CDS             20891..22927
                     /gene="glyS"
                     /locus_tag="AC1PIV_000019"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HIP6611082.1"
                     /translation="MTKNLLVELGLEEIPAYIVTPAMHQLRDRMATFLTDNRLAFDSI
                     DVFSTPRRLAVRVRGLADQQTDLTEDFKGPAKKIALDADGNFTKAAEGFVRGKGLTTA
                     DIEFREIKGEEYVYVTKHEAGQPAKTVLAGIPEVLKAMTFPVSMNWASNKFAYIRPVH
                     TLTVLLDDEALDMDFLDITSGRISRGHRFLGNETEIASADSYEADLRAQFVITDPAER
                     QNMIVEQIKAIEDKHNVTVEIDEDLLNEVLNLVEYPTAFMGSFDTKYLEVPEEVLVTS
                     MKNHQRYFVVRDKAGKLLPNFISVRNGNDQYLDNVIKGNEKVLVARLEDGEFFWREDQ
                     KLKIADLVERLKVVTFHEKIGSLYEHMERTKVIAEKLADLAGLSAGEKADVARAADIY
                     KFDLLTGMVGEFDELQGIMGEKYALLAGEKPAVAAAIREHYLPNSAEGELPESKVGAV
                     LALADKFDTLLSFFSVGLIPSGSNDPYALRRATQGIVRILEAFGWEIPLDQLIAELYS
                     LNFASLTYDNQPAVMDFIRARVEKMMDKTIPKDIREAVLASSTFVVRLQLAASSAIFQ
                     KAKEADYKEAVENLSRVFNLAEKAEVTAIDEALFENDQEKALAAAVAGLELTEDMAGN
                     LDKLFALSPVIAAFFDNTMVMVDDATVKANRLALLKALADKASAVAVFNLLNSK"
     gene            22937..23194
                     /locus_tag="AC1PIV_000020"
     CDS             22937..23194
                     /locus_tag="AC1PIV_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HIP6611083.1"
                     /translation="MEQAKIDRINELARKKKAEGLTEEELQEQAALREEYIEGYRRSV
                     RAHIEGIKVVDEDGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            23649..24020
                     /locus_tag="AC1PIV_000021"
     CDS             23649..24020
                     /locus_tag="AC1PIV_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611084.1"
                     /translation="MKKLVYALLVLAYVTVAYLSVYVLPHYYSGAIIGAAGASLGASF
                     KQFKEVKASPDKALLAYFKRDEKKASSLLLVLLGIFLFVSLVLEFNWQYGLAFVVAIS
                     YAMLWNVLHIQFLRKYYFKNA"
     gene            complement(24042..25379)
                     /locus_tag="AC1PIV_000022"
     CDS             complement(24042..25379)
                     /locus_tag="AC1PIV_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HIP6611085.1"
                     /translation="MNDLTKGKPIAVILQFAIPLLIGSFFQLAYNFADSMIVGHTLGK
                     DSFASVGSTASLIFLIIGFAQGVTNGLTIISAQRFGAGDLEGLKKSFVHGLFYASLIS
                     LLLTVSALAFLKPILVLMQTPVSIIDHSHAFLTAMFGGLTFTIFYNFLSSALRSLGNS
                     KTPLLALVIACFINIGLDFFFILVMNWGVFGAGFATILAQACSVLFLIFYIIHKVPHY
                     HIGLADLKLDRGNLKKHAQLAFPMGFQASIIAIGAMTLQFMVNQLGTDAIAAQAIALR
                     TDQLAMLPMVNLDLAIATFTAQNYGAKLYDRIREGVRHSLLLSIAWAIVFAVILILGN
                     RFFSGLFLPNASQTVLDLALVYYIINGSCYWIVASLFILRSFIQGLGKGFIPTLAGFG
                     ELIFRAAVAIIGMQYFGFYGTAAANPAAWIGSIIVLIPSSIIFMKKLKAGQSI"
     gene            complement(25700..26365)
                     /locus_tag="AC1PIV_000023"
     CDS             complement(25700..26365)
                     /locus_tag="AC1PIV_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA];
                     GO_process: GO:0034220 - monoatomic ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HIP6611086.1"
                     /translation="MPNYTIGILGLGVFGTTIAKTLHNYDCNIIAIDNHEQRINHLEP
                     ILTRGIVGDITDRSLLRAAGIGNCDAVVVATGENLESSVLAVMHSKVLGVPMVIVKVK
                     GTTAKEVLLRVGADKVISPERETGISLAKQLLHRDTTSLFELEGNVSIVEFHPPVKWI
                     GKTLGELKLRQHYKLNIIGYRSGENQELNIQLTPDYVFKSDELILAVTDHNTVDHFEE
                     LTN"
     gene            complement(26377..27726)
                     /locus_tag="AC1PIV_000024"
     CDS             complement(26377..27726)
                     /locus_tag="AC1PIV_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HIP6611087.1"
                     /translation="MSPFRIKLSPSQRIIISFLFVILTGSILLSLPISQISTSTASYW
                     DHLFTSVSMVCVTGLFTKAVAETYSTFGQIICMMLIQIGGLSLIGFIGLFALRGGRKM
                     NFINMATLQEALNRSDTKYFRNFLKSAFGFTLAVEAFGALLLSFHFVPEFGWARGLFT
                     SIFVAISAFCNAGFDNFGATSIMRYVDNPLINITLASLIIMGGLGFSVWFDLQTQIGQ
                     KRSLRKLGFHTKIVLGLTAIILTLGTLTTLLTEWNNPSTIGQLSFGHKLLASFFQTVT
                     MRTAGFASIDYTKAEPITLLLYIFQMMLGGAPGGTAGGIKITAFLTLVLYARSEILGL
                     PHTNFMGRTIDNLSIRKAFATFSVFLLMFIIGLFALALTDDRQPLLFLMFEVMSALAT
                     VGVTANLTPSLTMAGQAVIMALMFFGRIGPLSILASLSVRKLSKTESLQYAKSSMLV"
     gene            complement(27990..28529)
                     /locus_tag="AC1PIV_000025"
     CDS             complement(27990..28529)
                     /locus_tag="AC1PIV_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HIP6611088.1"
                     /translation="MNSKRQTLNFITMLAAQAVVISLIERLITPPFAFAPGAKLGLGN
                     LISLIAIFTLPTKDSLKVVALRLLISTFLGGTFSTFLYGFAGTTLSYVGMLSAKQLGP
                     NRVSPIGISILGGMLHNLGQLLVFATIARSFYVLNYLPILAFTGILSGLLVGLAATYL
                     LQKVGPLRHYHQQVLAEWK"
     gene            28712..30604
                     /locus_tag="AC1PIV_000026"
     CDS             28712..30604
                     /locus_tag="AC1PIV_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HIP6611089.1"
                     /translation="MTKNIVIVGAGYAGIAAARLLGKTFKKDQDVTVTLIDKNSFHTY
                     MTELHEVAAGRVEANAIKYDLQRIFKKYPKVQLVTDKVVEIDYDKKQVVAEHQTLDFD
                     YLLLAMGGEANDFGVKGVKEHGFTLWSIEAAERLHDHMIDACYRAMREHDEAKRRALL
                     TFTVIGAGFTGIEMIGELIDWVPILAREFKLDSKEFSLKVVEATPNILAMVTEKEQVK
                     ARKYLEKKGVELVLGDGVASVQEDSLTLSSGRQIPTYTSIWTAGVQANTDASEFGIEK
                     ARAGRLIANEFMEAKGKENVYVAGDLVYFEESEGKPTPQIVQAAEQTGHTAASNIIAA
                     IKGGEKHSYKGKYDGFMVSIGARYGVAFLMDKYHMSGFMAMAVKHMVNLLYFFTIRSF
                     FYMGSYVRHEFFDIQNKRNIFGGHTSGKGNLLWSVPMRVLYGSVWLYEGIKKAFGLFG
                     TTSWFGDQVVFPFPWLADPVSGASAAEAVSSASQAATAAAEVAEPIFGLSYAYGEAPM
                     AVLDKMPDWFATIMEFMMPNQEVALFMQKFMTVAEIGIGLALIAGAFVWIVSAATVAL
                     VVMFSLSGMFYWVNIWFIPAAISLMNGAGRAFGLDYWIMPWLGRFLDKKIYGKPKHIY
                     RIKDKK"
     gene            30623..31612
                     /locus_tag="AC1PIV_000027"
     CDS             30623..31612
                     /locus_tag="AC1PIV_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HIP6611090.1"
                     /translation="MVHQIWNTYPEIERGLEEVKSIILSEMMVLHPAVTAKIVEYVEA
                     PGKYLRAGLCLLFAQMTEGKISRSKLYFAAHLEVLHLATLIHDDVIDGADKRRGVTAA
                     HQQFSNRIAIYTGDYLLAYSSRLFGKGLRLLEVSRDDLDLGNDKLMETILRGELSQLL
                     NQFDANMTMKAYLKQIQGKTAFLFGLACQLGSFVPGQSRKDSSMAFRSGQALGMAFQL
                     RDDLIDYQLDVAESGKPRLQDIQNGIYTAPLLFAMREDKSIQQQLRAYIQSPTAEGLE
                     ILTDRIFATHAIAKTEKLIVSYLEKMMSFVDRISQLSTASMQNLVAIVFSHYF"
     gene            31691..32170
                     /locus_tag="AC1PIV_000028"
     CDS             31691..32170
                     /locus_tag="AC1PIV_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HIP6611091.1"
                     /translation="MKTTKVVLKSLVVLGAVFALVACGSKQESTSTSSSTTETVVLKD
                     GTYKAESGKDDYGYKIVHTLTVKDGKISESKFDYEAEDGSLKSANEEYNKNMKDKAGV
                     SAGEAIEQLNAALVEKQDLSAVEVVSGATHTSEDFKKSTEALLAAAAEGKTETVKLD"
     gene            32248..33297
                     /locus_tag="AC1PIV_000029"
     CDS             32248..33297
                     /locus_tag="AC1PIV_000029"
                     /EC_number="2.7.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HIP6611092.1"
                     /translation="MKKIASLLFVGLLMVLLVACGGKQNESLSVVKTPLTRSESLLHT
                     VVQLSIYHENQEEAMDEAVSYIKEMESLLSTNLEGADVYRINQAAGKEAVKVDERTFE
                     VIETAIDMSKESQGLFDISIGAVSNLWKIGDEDARKPSDEEIKAALPFINYKDITLDK
                     EKKTVFIKEGMTLELGAISKGYIADKVRELFASKGITTAIINLGGNVVVMGDSPTTQN
                     GWNVGVQDPDQVRGSTVGSVPGTHDSVVTSGIYERYLEVDGVKYHHILDPKTGYPVEN
                     DISGVTVFSKTSIQGDAFSTTLFLLGVEKGLDFINQIDGVEAVFIDKEQGVHLSDGLK
                     ESFELTNEEYHLVNE"
     gene            33290..34246
                     /gene="menA"
                     /locus_tag="AC1PIV_000030"
     CDS             33290..34246
                     /gene="menA"
                     /locus_tag="AC1PIV_000030"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HIP6611093.1"
                     /translation="MNKSTKGLSLSVFLEFVEMKTKVASVFPMTLGILWSLYRYQAFN
                     WLNTLLFIIAVLSFDMCTTAINNSMDYHKAKDEAYRQESNVIGKFSLDFRQMIGIVLA
                     LLIFSLLVSLLLVWRTSWLLLPMGALCFLIGIFYTFGPIPLSRMPLGEVFSGVTMGFG
                     IFFLAVFIQQPDLLLTSQVSGQWMTLQFSWIKIIEIIFMSIPLVTLIANIMLANNTCD
                     LEEDIRNHRYTLVYYIGKKNALKLYFVLASLPWLLWIIYCLIGFLPIWALAGLIGVWP
                     AYKSLETFLKKQLKRETFIEAVKSFVLFALLYVVILALALIF"
     gene            complement(34554..34982)
                     /locus_tag="AC1PIV_000031"
     CDS             complement(34554..34982)
                     /locus_tag="AC1PIV_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HIP6611094.1"
                     /translation="MTFKSILKQLKLFDYILIGFTLVLSFLPAIFTYTQLTTDANEAK
                     TIAYVRINGEVVDQFELSKDTPRQEKTYYPNEGQYNIIEVDGERIRVKEDNSPDQIAV
                     MTSWISQPGQLSVCLPHNLLIEIKSVGGENTDEEELILPL"
     gene            complement(35035..35382)
                     /locus_tag="AC1PIV_000032"
     CDS             complement(35035..35382)
                     /locus_tag="AC1PIV_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611095.1"
                     /translation="MNVNKPKLILTLIVLSYTTFCSLYIHSYLTGDNPPIFILPFTIL
                     PILNSDWQTTSPESNAVQEAIHLYRKPLLCFLFAGLVLTFSIGFFTGQIKPLLAGFWG
                     IFALLLFIGQLKK"
     gene            complement(35372..35716)
                     /locus_tag="AC1PIV_000033"
     CDS             complement(35372..35716)
                     /locus_tag="AC1PIV_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HIP6611096.1"
                     /translation="MNKPFTPKQTCRFFVLFYALFSAFFIYSYMVNEPISGSFLLMLP
                     PIQIIRSFKTEEEKRYFIIQAIFALFAMTLTYSVGIWLGHVKPHILILPAGFALAILY
                     RLYFKKEKTDER"
     gene            complement(35729..36811)
                     /locus_tag="AC1PIV_000034"
     CDS             complement(35729..36811)
                     /locus_tag="AC1PIV_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HIP6611097.1"
                     /translation="MKKETFQDKLIKRFYGIAGPLDEFRQKEASRLGNTCFILLFWGT
                     MALTLLALALSKRYPEVVAYGYPTALLLSTLSSSMYMTSKMRHSQVDSLDVEELTTKE
                     QKQLKGASIKFALYFTAVMYIWTVVFGAWMEGLNPFDHLFDLRKFLAACLGGIFTGIA
                     LEIMLRKRMKKAENLTISSAISKEEPKWIKNMIKRFYGIRGPLDEYRQAEADAIGGQA
                     FIYYFYFLALGNAIAYFLAYRYPVEVAAYYPMIIAFFSIILIGIVNMRTLHADLPQYD
                     MEELSPEERQGQTLNPLVWGLGVALLSSLFAGLSDLFSLQLPLLASSFHVKSLLFGGM
                     MGLFASLALSALAYLQKLEADTAKKK"
     gene            complement(36822..37022)
                     /locus_tag="AC1PIV_000035"
     CDS             complement(36822..37022)
                     /locus_tag="AC1PIV_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611098.1"
                     /translation="MKKNIRQALISTLIFIPLFVLFQLWGNSGAEILHTISQAKFWLQ
                     LLIAGTIYFLGFVYILPLFVQK"
     gene            complement(37037..37570)
                     /locus_tag="AC1PIV_000036"
     CDS             complement(37037..37570)
                     /locus_tag="AC1PIV_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HIP6611099.1"
                     /translation="MKDIFTKILNQATKDFYSISGPMDEMRLQESYRLSNTIVMIVFP
                     ILLIGNTIALLIALRQPEKVGFLLPLTNILIIGFTQALASHLALKNGISQSYEDEINV
                     TKLNKSLVKSSRSTFFGAFLASTTAPAFYKEWSVFLEELTDPTLLLGRLIVAGAITFI
                     HYYYCKKQLQKKILANK"
     gene            complement(37581..37769)
                     /locus_tag="AC1PIV_000037"
     CDS             complement(37581..37769)
                     /locus_tag="AC1PIV_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HIP6611100.1"
                     /translation="MNRVKDYRLLLGISQLDLAKAIGVSRQTINMIENNKYNPSLDLC
                     INLAKALQTDLNSLFWNQ"
     gene            38040..38990
                     /gene="rsmH"
                     /locus_tag="AC1PIV_000038"
     CDS             38040..38990
                     /gene="rsmH"
                     /locus_tag="AC1PIV_000038"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HIP6611101.1"
                     /translation="MTKEFNHTTVLLHETVDMLDIKPNGIYVDATLGGAGHSEYLLSQ
                     LTDGGHLYAFDQDQTAIDHAHIRLASYIEKGQVTFIRDNFRNLKTRLAELGVTEIDGI
                     CYDLGVSSPQLDERERGFSYKQDAPLDMRMNREGHLTAYDVVNNYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQARAVKPIETTTELAELIKSAKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAIDLLALDGRISVITFHSLEDRLTKQLFKEASTIDVPKGLPFIPD
                     DLKAPLELVNRKPILPSQEELEANNRAHSAKLRVAKKVHK"
     gene            39001..39324
                     /gene="ftsL"
                     /locus_tag="AC1PIV_000039"
     CDS             39001..39324
                     /gene="ftsL"
                     /locus_tag="AC1PIV_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HIP6611102.1"
                     /translation="MLQEKRREATMRVIGDKIRTFTRVEKAFYSSIVLSGLALAIGII
                     FMQTRLLQLQSSMAKVNQDISQKQIEINDAKQAVNELTRSARLMEIAEKAGLTFNNDN
                     IGVAE"
     gene            39324..41573
                     /gene="pbp2X"
                     /locus_tag="AC1PIV_000040"
     CDS             39324..41573
                     /gene="pbp2X"
                     /locus_tag="AC1PIV_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP2X"
                     /protein_id="HIP6611103.1"
                     /translation="MPRRNNKLLRYVLKKRYVPSKNRRRVGQSLLLLTVFVFFLFLIN
                     FAYIIGTDSKFGVDLSERADAVHQREVIVQAKRGTIYDRTGIPIAEDSTTYTVYAIID
                     TEYVSELKKVLYVQSSQFSKVAEIFKKHLGMETDYVMEQLNQPELKQVYFGTLGKNIS
                     YSTMSSIQEEMKAAGIEGIAFNASPGRMYPNGNFASIFVGLANLVENKDGSHSLQGVS
                     GLEYYLNDILAGQDGKVIYEKDSQGRVLPGTEKVETETVNGQDVYTTISADLQRSLET
                     NMNTFFDNAKGRYANATLVSAKTGEILATTQRPSYDSDTKEGLGQEGLLERSLLYQEA
                     FEPGSTMKVLTVASAIDNGTFDPNAYYTNNEYVIADAKINDWTLNAGYSAVTLNYAQG
                     FSLSSNVGMTLLQQQMGDEKWLNYLTKFRFGYPTRFGMGDEAPGMVPEDNIVSIAMSS
                     FGQGISANQAQMLRSFTAIANNGIMLEPKFISALYDPNTDTARVSSKEEVGNPVSEQA
                     ADDTLRYMINVGTDPVYGTLYSHDLQGPAIQVDGYDIAVKSGTAEIASEDGQGYIKGA
                     YINSVVAMIPAEDPEFIMYVTIRQPEVLNVLSWRDIVSPTLKEAMLLKDNLNLDSPAP
                     ALARVANETEYQLPDLIGKAPGESAEELRRQLVQPVILGNGAEIKKVSVEKGSKVIAN
                     QQVLLLTNKFEEMPDLYAITKENMDIFAEWTGIEVTYKGTGSKVVDQSVEVGTALNKT
                     KKITITLGD"
     gene            41575..42573
                     /gene="mraY"
                     /locus_tag="AC1PIV_000041"
     CDS             41575..42573
                     /gene="mraY"
                     /locus_tag="AC1PIV_000041"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HIP6611104.1"
                     /translation="MQFALMSGLVAFLATVLLIPRFITFYQAKRIEGQQMHEDVKQHQ
                     FKAGTPTMGGTVFLVVAILVSLLFATAFQLLTGGVLAILFILALYGVVGFLDDFLKIF
                     RKINEGLNPKQKLALQILGGIVFYFVHVRGAGGGELNVFGHMVHLGVLYFPFVLFWLV
                     GFSNAVNLTDGIDGLASISVVISLLAYSVIAFNEQKFDILLVCVTMIGGLLGFFVYNR
                     KPAKIFMGDVGSLALGGMLATISIALRQEWTLLLIGLVYVIETSSVMLQVSYFKYTKK
                     RFGEGRRIFRMTPFHHHLELGGLTGKAEKWSEWKVDFFLWSVGLIMSLITLAILYL"
     gene            42666..43499
                     /locus_tag="AC1PIV_000042"
     CDS             42666..43499
                     /locus_tag="AC1PIV_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611105.1"
                     /translation="MEQFNQEQLYGVVIQTMTAASQLPMVKVNREEFLKTRFKDSPYL
                     DKIIADGPTAVFTTKALRKEAEKIINDMTTKTSLISFAAGLPGNPFTAVAAGTADIAQ
                     YFGFALNLSQQIAYLFGEDELFVGEGKEISEEVQIRIIAYIGVMFGAGGSAVLLNKVS
                     KTVGANIGKKVAMQALTKTTWYPLVKKVAAVIGVKITKKTVEKTIANAVPILGGLISG
                     GLTYFTFQPMGGMLADTFVKKINGDFDGELELTEAFKASLEEEKELGIIEAEFTEASE
                     S"
     gene            43578..44921
                     /locus_tag="AC1PIV_000043"
     CDS             43578..44921
                     /locus_tag="AC1PIV_000043"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HIP6611106.1"
                     /translation="MKFTDMKLKPYIQEALKEINFVQPTEVQEKLIPVVLSGRDLIGE
                     SKTGSGKTHTFLIPIFQKLNEELDQVQAVITAPSRELATQIYQAARQLASHSDTEVRV
                     TNYVGGTDKNRQIDKLQASQPHIVVGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEQIKTHTVISDTIE
                     NWLISTKGRDRNAQILEVTKLMQPYLAMIFVNTKTRADELHSYLTANGLRVAKIHGDI
                     PPRERKRMMNQVKNLDYQYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLSGIAITLYQPSDDADIRELEKLNIKFLPKEMKNGEFVDTYDRDRRANREKSREK
                     LDLEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRVEARAKGRAERKAKRQTF"
     gene            44939..45163
                     /locus_tag="AC1PIV_000044"
     CDS             44939..45163
                     /locus_tag="AC1PIV_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HIP6611107.1"
                     /translation="MLQNILSFYLQGLLIASLLIITSSLVWFIWRATKGVDKTLQERQ
                     DFLFDLLMINVMTIPIAAFGVVGILLMFKA"
     gene            45177..46094
                     /gene="trxB"
                     /locus_tag="AC1PIV_000045"
     CDS             45177..46094
                     /gene="trxB"
                     /locus_tag="AC1PIV_000045"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HIP6611108.1"
                     /translation="MYDTVVIGAGPAGMTAALYAGRSNLKVALLERGIYGGQMNNTAE
                     IENYPGYDHISGPALAEKMFEPLEKFGVDHIFGTLVRIEEEGQIKKVITEDGVLETKT
                     VVLAMGAKHRLLGIPGEDTYNSRGVSYCAVCDGAFFRGQKLLVVGGGDSAVEEALFLT
                     QFAESVTIVHRRDQLRAQKVIQDRAFANEKINFIWDSVVEEIKGDDLRVQSVVIKNVK
                     TEEVSELDFGGVFIYVGLDPMTDTVADLGITDEAGWVITNEKMETTQSGIYAIGDIRQ
                     NQLRQIATAVGNGAVAGQEVYNYITELAE"
     gene            46104..46643
                     /locus_tag="AC1PIV_000046"
     CDS             46104..46643
                     /locus_tag="AC1PIV_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceD family protein"
                     /protein_id="HIP6611109.1"
                     /translation="MFHIYDIQKNLDGIFFDKTLDLQEELQARNGEVLGLSPVQVTGN
                     VRFESGFFFLDYQMTYDITLASSRSLQPVVLHEVQNVNELFVANEAVLKEQDLIDEDM
                     VLVVEDDHIVLDESVADNILLAIPIKVLTPEEEAGQELPSGKAWALMTEEDFQQKAQE
                     KKEANSPFAQLQGLFGDED"
     gene            46740..48167
                     /gene="gndA"
                     /locus_tag="AC1PIV_000047"
     CDS             46740..48167
                     /gene="gndA"
                     /locus_tag="AC1PIV_000047"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004616 - phosphogluconate dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HIP6611110.1"
                     /translation="MTKANFGVVGMAVMGRNLALNVESRGYSVAIYNRSADKTEDVVA
                     SNPGKNLVPSYDVESFVASIEKPRRIMLMVQAGPGTDATIQALLPHLDEGDILIDGGN
                     TFYEDTIRRSKELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGAPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSVDEMAD
                     IFTDWNQGELDSYLIEITADILKRKDDQGQDGPIVNYIMDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKDERVAASKVLPKPAPFAYEGDKAELVEKIRQALYFSKI
                     MSYAQGFAQLRVASKENNWNLPFGEIAKIWRAGCIIRARFLQKITDAYGRDEDLANLL
                     LDEYFLDVTAKYQQAVRDVVALAVQAGVPVPTFSAAITYFDSYRAENLPANLIQAQRD
                     YFGAHTYNRKDKEGIFHYDWYSESK"
     gene            48249..48938
                     /locus_tag="AC1PIV_000048"
     CDS             48249..48938
                     /locus_tag="AC1PIV_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HIP6611111.1"
                     /translation="MAKKILIAGKERNLSHFVSMELQKKDYLVDYASTGKEAMSLAHE
                     TDFDLILMSFQLSDMSSKELATELLAIKPATVMIVVVEPTEVSQYGEEVLSYAVSYVV
                     KPFVISDLVEQISAIFRGRDFIDNNCKQVHMHAAYRDLKVDFQNRTVTRGDELINLTR
                     REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPHQDSYIK
                     TVRGVGYAMRD"
     gene            49028..50158
                     /locus_tag="AC1PIV_000049"
     CDS             49028..50158
                     /locus_tag="AC1PIV_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014917300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HIP6611112.1"
                     /translation="MNTSFKEKVILILLSGATLLAVLNWSSIYGAIQQLLGSMNSLFI
                     GAIFAFILNVPMKKLEDQFEKISFLKKSKRSLAIVGVLIGFALIVTGLVVIVLPTLVT
                     TVSELVSVSSTAIPKSVNALTNFLESNGLLSGQIGDQIASFLDQLKNLTLISSLVTPI
                     LSGLVSNVTGIFSNTMTLIMAFFFTLAILGSKEHLQAMTRKFLQATLPEKAVRVVNYI
                     GEVIVDTYDRFLMSQIVEACIIGTLVFVSYSLSGIPYASMAGILAGVLSFVPYIGPFS
                     ACLISALFVAVQNPLLALWSIALFQIIQLIEGNVIYPRVVGQSVGLPTLFTLAAALIG
                     GNLFGLLGMVFFTPIFAVVYRLVREWVASRLKKQDELLVESE"
     gene            50230..50721
                     /gene="nrdR"
                     /locus_tag="AC1PIV_000050"
     CDS             50230..50721
                     /gene="nrdR"
                     /locus_tag="AC1PIV_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HIP6611113.1"
                     /translation="MRCPKCQSLKSSVIDSRQAEDGNTIRRRRSCDQCGQRFTTYERI
                     EEKTLVVVKKDGTREQFSREKIFNGIIRSAQKRPVSTDDIDEVVNRIEQKVRAQGDSE
                     IESDVIGNLVMEELVELDEITYVRFASVYRSFKDVGELENLLKQMISKGSKVKPGKKD
                     ETK"
     gene            50708..51859
                     /locus_tag="AC1PIV_000051"
     CDS             50708..51859
                     /locus_tag="AC1PIV_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation/membrane attachment
                     protein"
                     /protein_id="HIP6611114.1"
                     /translation="MKPNDLFAYIKISPFTPDIVSLSKCYQPIIGFDALALYYYFYSF
                     ADQGQGRYKWTVILNHMDFGMNRLEKALDVLTAMGLLELYRADELTGLALQAPLTVKS
                     FLAKPLYKNLLARKIGESSMENLLVHQPNQEQNISKTFSQVFTMDGQAPVVFEPKHDF
                     DWSAFKALMAKDKLLFQDEAEDIIALSYIAEQAGWTWLETYRQAKATAIGQMISTKRL
                     QQSRQSLPTESANLTAQEQAIVREAKSKSSLTFLSFIKEQRKAAVTGTERKCLTDLAN
                     LGLLDEVINVLVLYTFNKVDSANLNEKYAMKLGNDFSYKGIGSAEAAVLYLRELKTGQ
                     AVTKSSQPQKSNVPEWSKEEVVMDNSPEAQARMEALRKRMLENESKGGS"
     gene            51859..52758
                     /gene="dnaI"
                     /locus_tag="AC1PIV_000052"
     CDS             51859..52758
                     /gene="dnaI"
                     /locus_tag="AC1PIV_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HIP6611115.1"
                     /translation="MKSVQDRLSQATNPSSKSYQQLYQEIVSDPEVAAFIKKEGLTQQ
                     EITLSISKFLEYISQRDLFVKQDETYIAKGYQPVLVMNEGYADVSYLETEELVEYRRL
                     EAIKNRIQLINMPQALKKVTIADLDFTDSNRIEVYDAIDAFVEQVGEHYKGLYLYGDF
                     GIGKSFLMAYMAHRLSTNRHLSTTILHYPTFVVDIKNAIKDGSVKERIDEIKLAQVLV
                     LDDIGAEQHSPWVRDDVLQVILQYRMQENLPTFFTSNFSFDELERHFASGKSGDETWQ
                     AQRVMERIRYLARDLHLKGNNRR"
     gene            52755..53467
                     /locus_tag="AC1PIV_000053"
                     /pseudo
     CDS             52755..53467
                     /locus_tag="AC1PIV_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647269.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
     gene            53486..54796
                     /gene="der"
                     /locus_tag="AC1PIV_000054"
     CDS             53486..54796
                     /gene="der"
                     /locus_tag="AC1PIV_000054"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HIP6611116.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRKFSLIDTGGIDDVDAPFMEQIKHQAEIAMDEADVIVFVVSGKEGVTDADEY
                     VSRILYKTNKPVILVVNKVDNPEMRNDIYDFYSLGLGDPYPVSSVHGIGTGDVLDAII
                     ENLPAQEAEENPDIIKFSLIGRPNVGKSSLINAILGEERVIASPVAGTTRDAIDTHFT
                     DPEGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIERSDVILMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKQWEDDIRDQFQYLSYAPIIFVSALTKQ
                     RLHKLPEMIKAISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVVFVNEEELMHFSYMRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            54864..55202
                     /locus_tag="AC1PIV_000055"
     CDS             54864..55202
                     /locus_tag="AC1PIV_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HIP6611117.1"
                     /translation="MVAVPIWRSFLILLSFSSFFLVFYEDSQYKPFGFRYWLGLVACI
                     WLNLVTLASYFIAFTGGSIMVYNQYKQPLVVIFLFCLFVASMLTLLSFKAIKMMIRRT
                     KYYRQVRKVG"
     gene            55204..55512
                     /locus_tag="AC1PIV_000056"
     CDS             55204..55512
                     /locus_tag="AC1PIV_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611118.1"
                     /translation="MEFLGELLVEFLTGLADFDEKKHPPFGIRYWLGWLGVLIHVLLL
                     ALLTCVTVFFFKFFLVGKGLINVVVAVVFLLFALFWLWKFGKTILKMWQATIYYLAIH
                     "
     gene            55651..58743
                     /locus_tag="AC1PIV_000057"
     CDS             55651..58743
                     /locus_tag="AC1PIV_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0140658 - ATP-dependent chromatin
                     remodeler activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2-related protein"
                     /protein_id="HIP6611119.1"
                     /translation="MGRMMPGRIRQEGIDLYEAGKLTVLHSENGKMVLDIAGERFTYG
                     DADSDLQCSCQLFQSKGYCQHLAATEYFLKNDASGKDMKQSLKEDGEQHKETVRRTYF
                     GGLFLDEILRPEPELGIKYQLSVEGSLLPYDRQIDWTLKITRLPDTRSYIVRDIGAFL
                     RIVKANGHYQIGKNYYEQVTYENFDEPSQALLDFLWALVPEKVGIDSDILTHFGRHFR
                     LPQAYFEEGLELLNQLEHFNFSYQQQSYSSLMVLPLTGEEGLYHFEVTVHTQMIEMVI
                     HEKTVRPLFHGRYLLVNGTVYSVNRHQEHLIYQISELVPTESGLRKVQVDFPDQNRLA
                     LSLLDLQTIGTVKAPKRFIIHDFKPEFHIQMEANDSLSLQLVLDFDGRKVRSEEDLAL
                     LPFASHFQHLERVYQAIRLAGFRGTYHAQRAALSQQELYPFFQQQLPILQKMGQVHLA
                     ERLQALYIEAKPQLEIVRNGSLLDISFDLSGIEQSEIDQAITALLNQEDHYTSPSGKV
                     FVFDEETKKISQTLIYLRARHGKEGQVQVHALAGYQLAQSLSQFNQVSFSKEFEEMAS
                     YLAQPDLFPLPAVEVTTSLRDYQQTGLKWLTMLDTYGFGGILADDMGLGKTLQTIAFL
                     SSRMTKDSKVLILAPSSLIYNWLDECKRFAPSLDVAVVHGNKEQREEIIANDHQVLVT
                     SYPSFRQDVALYRQERFDYLILDEAQVMKNAQSKIAQLLREFEVGNCFALSGTPIENH
                     LTELWSIFQIVLPGLLPGKQDFGKLAAKDIARTIQPFVLRRHKEDVLQELPDLIEVNV
                     LNELTDEQKAIYLAQLQQMRTQIAGADDAQINRSKIEILSGITRLRQICDTPSLFMEE
                     FSGESGKLNSLKELLLQLKEGEHRVLIFSQFRNMLEKIEEQLIEIGMTSYTLTGSTPA
                     NQRQEMTQAFNAGSRDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAISRAHR
                     MGQTEKVECYRLITRGTIEEKIQELQENKKNLVKTVLDGNESRANLTVEDIREILGIE
                     "
     gene            58822..59484
                     /locus_tag="AC1PIV_000058"
     CDS             58822..59484
                     /locus_tag="AC1PIV_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611120.1"
                     /translation="MIRHEKRFPLVADDEVLVGENPIMSLYDESDLISNIRGPYQEKE
                     FSWSTDSQRVASAKPVAQTEDELLPPLFEAKPSHYSRKERLQQLTKTKPSPVKTQGQL
                     AREQAREDLKKKRSATYLRDEKPAPAKVVVKPPVVSTAESKAGRLTRLADNLRQTDYI
                     LADMPAVYSLKKEDREQEQVIKKNSYDFLRKSQVYNYPERRQQRDRQVAQELNLTHIE
                     EE"
     gene            59486..60817
                     /gene="murC"
                     /locus_tag="AC1PIV_000059"
     CDS             59486..60817
                     /gene="murC"
                     /locus_tag="AC1PIV_000059"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HIP6611121.1"
                     /translation="MTKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGIQILPFDEKNITADVELIAGNAFRPDNNVEIAYADAQGYTYKRYHEFLGEFMKG
                     FTSLGVAGAHGKTSTTGLLAHVMRNITDTSFLIGDGTGRGSANAQYFVFESDEYERHF
                     APYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQVKNALFVFGEDEQLRRITANA
                     PIYYYGLEDNNDFVAYDLKPSTSGSQFKVRHGEEELGKFQIPTFGKHNVMNATAVIAN
                     LYIAGFDLQLVAEHLKTFGGVKRRFTEKIVNDTVIIDDFAHHPTEIIATIDAARQKYP
                     SKELVAIFQPHTFTRTIALLDEFADALNGADAVYLAQIYGSARETDNGQVKVEDLAAK
                     INKKGGLVTVENTSPLLDHDNAVYVFMGAGDIQSYEYSFERLLSNLTNNVQ"
     gene            60873..61358
                     /locus_tag="AC1PIV_000060"
     CDS             60873..61358
                     /locus_tag="AC1PIV_000060"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIP6611122.1"
                     /translation="MEIRFATPSDLEQVVLIENANFSKEERIAESVLATYLNTLSKTC
                     LIMEHDEEIAGYLLSCPSVSQTVTDDIFYLTESDMPTGGHLAIASLSVADAYKGQGVG
                     TLLLAAIKEVALAGGFEGVSLTCKRYLISYYEMNQFEDFGPSLSQFGGQRWSDMYWKA
                     L"
     gene            61430..63247
                     /gene="mltG"
                     /locus_tag="AC1PIV_000061"
     CDS             61430..63247
                     /gene="mltG"
                     /locus_tag="AC1PIV_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HIP6611123.1"
                     /translation="MTKDTNEKNTQSSGFRDQILRDLEELKVKRLAEQSADVLVDKRN
                     EVINELQPSLAEEKAPHRETEIVKVEGIAFPDSYLSEEQQESEVMTESIEEPTSETLA
                     TPETFVIEKEVVSSPVPQDTVERNLEKLRNLVAANTAGFDEVPSSSSVSEPVESVLSE
                     KSSLEDTFLEFPTEDVSAVTGDTEIIALEETIIAPKTTAIVPEVDKQMQETQPRRRTT
                     HRTSKQRRKKQDNAAKHIVSVIMSIVVVAVLVTGVTGYMWVKSSLEPVNAKATETIQV
                     EIPEGSSTLEIGKILVDNKLIKNATIFNYYSKIKSYNNFQSGFYNLKQNMSVDDIAKA
                     LQESGTPTAQKEAAGKVLIVEGYTLTQIAQAITDNTNTKDKNDKTPFTAEQFMATVTN
                     QDFINRMVATYPKLFASLPAADSGVIYQLEGYLFPAVYEYSDETTIEELVEQMIAAMD
                     NRLQPYYETITAKNLTVNEVLTLASLVEKEGSTDEDRRNIASVFFNRLNAAMPLQSNI
                     AILYAQGKLGQETTLAEDAAIDTSIESPYNIYWTPGLMPGPVDSPSLSAIEAVINANT
                     TDYLYFVADVTTGNVYFTNNIDEHNQNVAKYVNAHLNNE"
     gene            63321..63803
                     /gene="greA"
                     /locus_tag="AC1PIV_000062"
     CDS             63321..63803
                     /gene="greA"
                     /locus_tag="AC1PIV_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HIP6611124.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEIVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISTIETKIRYAEIVNSDAVAADEVAIGKTVTVQEVGETE
                     EEVYHIVGAAGADVFANKISNESPIGHALIGKKTGDVATIETPAGSYDVKILKVEKTK
                     "
     gene            complement(64002..64916)
                     /gene="yidC"
                     /locus_tag="AC1PIV_000063"
     CDS             complement(64002..64916)
                     /gene="yidC"
                     /locus_tag="AC1PIV_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HIP6611125.1"
                     /translation="MKNKRLLILSGMALSTLLFLSGCVQTDKSGNPTGPIWDWLGQPM
                     SNLIRFFAEDQALGFGLAIIIVTLLVRFIILPLGIYQSWKAAIQSEKMNYLKPILGPI
                     QERMKNASSQEEQLAAQQEYFATQKQYGVSMLGGIGCLPMLIQMPFFSAIYFAARHTP
                     GISEATFLGINLGSTSLILTVVAGILYYAQSLLMQVGMDEEQKKQMKTMALMNPIMIM
                     MFSFGSPAGVTLYWVVGGLFGILQQAITNFILKPRIRKQVEEEFKNITVSATPRKTKD
                     VTPTASAVIEEKTSNKKRNRNAGKQRSR"
     gene            complement(64986..65267)
                     /locus_tag="AC1PIV_000064"
     CDS             complement(64986..65267)
                     /locus_tag="AC1PIV_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HIP6611126.1"
                     /translation="MRKVKMIASGRVQGVGFRWSVQFLAVEIGDIYGRVWNNDDGTVT
                     ILAQSDNAEKLSHFIHEIRKGPSRMAKVIYLDVTLANFEDYKDFQVSYR"
     gene            65397..66137
                     /locus_tag="AC1PIV_000065"
     CDS             65397..66137
                     /locus_tag="AC1PIV_000065"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="HIP6611127.1"
                     /translation="MEIIRSKANHLVKQVKKLQQKKYRTSSYLIEGWHLLEEAMEAGA
                     NIEHIFVVEEYFEKVAGLANVTVVSPEIMQELADSKTPQGVVAQLALPSQRLPETLDG
                     KFLVLEDVQDPGNVGTMIRTADAAGFDGVFLSDKSADIYNMKVLRSMQGSHFHLPVYR
                     MPISSILTALKSNQIQILATTLSSQSVDYKEITPHSSFALVMGNEGQGISDLVADEAD
                     QLVHITMPGQAESLNVAIAAGILLFSFI"
     gene            66184..66666
                     /locus_tag="AC1PIV_000066"
     CDS             66184..66666
                     /locus_tag="AC1PIV_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HIP6611128.1"
                     /translation="MVAYKQDKEYMHYVGHLIATPKVQKLGKIPHHYHSTRLEHSINV
                     SYTSYKIAKKFGWDAKSTARGGLLHDLFFYDWRDTKFNKSHAWVHPRIAKRNAQKLIQ
                     LNKLEEDIIVKHMFGATIAPPCYKESWIVTCVDKYWAVREWSLPLQHKWKNRKVFRFQ
                     "
     gene            66688..67389
                     /locus_tag="AC1PIV_000067"
     CDS             66688..67389
                     /locus_tag="AC1PIV_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HIP6611129.1"
                     /translation="MNNDSFIINQVDNTALNRFFGKIYGVVAMGIGLSALVSFLAVTV
                     FQSLLLSLLSAGSIIMMLIMIGQIALVVSASAMAAKNSPMALPMFLAYSVTNGITISM
                     ILMFYTSETVVLAFVSAALMFAIMAVIGMTTKKDLSGMAQALRAALWGIIIASVINIF
                     LRSSGLSFMMSIISVLVFSGLIAYDNQRIRNVFEQTGGNVGQGWVVSMALQLYLDFIN
                     LFLNLLRIFGGLSRD"
     gene            complement(67438..68769)
                     /gene="pepC"
                     /locus_tag="AC1PIV_000068"
     CDS             complement(67438..68769)
                     /gene="pepC"
                     /locus_tag="AC1PIV_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HIP6611130.1"
                     /translation="MSTLDFDFTERLYANYLANPSLQATENAVSHNGLLKSLETRQSA
                     IDNDYVFSIDLTKDAVSNQKASGRCWMFAALNTFRHKLISDFKLENFELSQAHTFFWD
                     KYEKSNWFLEQIIATADQEIGSRKVKFLLDTPQQDGGQWDMVVALFEKYGVVPKSVYP
                     ESISSSASRELNQYLNKLLRQDAQILRDLLAKGASPEEVQTQKENLLQEIFNFLAVNL
                     GLPPRSFDFAYRDKDNVYHRDTNVTPQAFYEKYVGLKLSDYVSIINAPTTDKPYNKSY
                     TVELLGNVVGAPAVRYLNVEMNRFKELAIAQLKAGESVWFGSDVGQSSNRQTGIMATN
                     TYDFSSGLGIHFHQDKAGRLDYSESLMTHAMVLTGVDLDDNEQPLKWKVENSWGDKVG
                     DKGYFVASDSWMDEYTYQIVVRKEFLTQEELAAYQAQPQVLAPWDPMGALA"
     gene            68903..70150
                     /locus_tag="AC1PIV_000069"
     CDS             68903..70150
                     /locus_tag="AC1PIV_000069"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HIP6611131.1"
                     /translation="MTKTPFVSKEVLENITEQFPTPFHLYDEKGIREKARALNAAFSW
                     NKGFKEYFAVKATPTPAILKILQEEGCGVDCATDVEVLMSEKLGFKDIMFTSNDTQAQ
                     EFVYARKVGATINLDAYEHIEFLKNVAGIPETVCLRYNPGGVFSLGTDIMDHPEESKF
                     GMTKDQLMKGYKELKELGVKQFGIHAFLASNTVTNDYYPVLARQLFELALEIREETGV
                     TLDFINLSGGIGVNYRPEQEPNDIAVIGEGVRKVYEEILTPAGMGHVKIFTELGRFML
                     APHGHLITKVLHRKETYRTYIGVDASAANLMRPAFYGAYHHITNITRPDAPIEVVDVA
                     GSLCENNDKFAVNRELPRVEVGDTLVIHDSGAHGFSMGYNYNGRLRSSEILLQEDGTA
                     RMIRRAETPEDYFATIYGFDFDR"
     gene            70250..70486
                     /locus_tag="AC1PIV_000070"
     CDS             70250..70486
                     /locus_tag="AC1PIV_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HIP6611132.1"
                     /translation="MNLGLAILLIVLAFAGGVALGIYLSRRQVENYIADKPILDENAL
                     RLMMSQMGQKPSEAKVQQVLRQIKSQQKVASKKK"
     gene            70576..71370
                     /gene="racE"
                     /locus_tag="AC1PIV_000071"
     CDS             70576..71370
                     /gene="racE"
                     /locus_tag="AC1PIV_000071"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008881 - glutamate racemase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HIP6611133.1"
                     /translation="MDNRPIGFLDSGVGGLTVARELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKNVKMIVFACNTATAVVWEEVKEKLDIPVLGVILPGASA
                     AIKATQTGKVGVLGTAMTIQSDIYREKIQALSPETQVDSLACPKFAPLVESNSHQSSL
                     AKKVVYETLRPLVGQVDTLVLGCTHYPLLRPIIQNAMGKDVKLIDSGAECARDISVLL
                     NYFQINRSRTEKDIQHRFYTTASPAAFKEIAESWMGIDIHVEHVEL"
     gene            71367..72377
                     /locus_tag="AC1PIV_000072"
     CDS             71367..72377
                     /locus_tag="AC1PIV_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009143 - nucleoside triphosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HIP6611134.1"
                     /translation="MTDKIYEYRDEHNWFIGKASFANLFGSFGENGREQEIYQIGQLF
                     DKLIAGNYEDENFNQCVNIEVIKLQSEFALFQFACDTLNELNNRQFKALQHQGAILVT
                     ENDKLLLVHLPQAGVSTADFFGQDKGLASVGDTILIATKNEGKTKEFRKFFERFGYQV
                     ENLNNYPDLPDVAETGMTFEENARLKAETIAELTGKMVLADDSGLNVDALGGLPGVWS
                     ARFSGPDATDELNNAKLLHELAMVFELKDRSAQFHCTLVMAAPNRDSLVVEADWEGFI
                     GMDLRGENGFGYDPLFLVGETGKTSAELTLEEKNKISHRAQALEKLVEAFPVWQEQAK
                     QS"
     gene            72350..72877
                     /locus_tag="AC1PIV_000073"
     CDS             72350..72877
                     /locus_tag="AC1PIV_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HIP6611135.1"
                     /translation="MAGASKTILVMSDSHGDRQIVEDIKHHYLSKVDAIFHNGDSELD
                     SQDSLWDGIQVVNGNCDYFGGYPDQLITQLDGVTIAQTHGHLYGINYGWQRLDYWAQE
                     VDADICLYGHLHVPDAEVRGKTLFLNPGSVSQPRGLVRECLYALVTIYDDHFHVDYYN
                     RQHQLYPALTKDISR"
     gene            72874..73332
                     /gene="cbpB"
                     /locus_tag="AC1PIV_000074"
     CDS             72874..73332
                     /gene="cbpB"
                     /locus_tag="AC1PIV_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0180001 - cyclic-di-AMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP-binding protein CbpB"
                     /protein_id="HIP6611136.1"
                     /translation="MIAREFEAFLLDQEETFLTPADKLAVIIDTHNIDHAKLLLSHMT
                     YSRVPVVTEDGRFFGTIGLTEIIKYQAENELSDDELNRDISVIVKTDEETVGLDYDLT
                     EVMRKLVDQSFLPVLGENREFMGIITRKSILKAINALLHNFPLASKEGKK"
     gene            73329..74060
                     /gene="xerD"
                     /locus_tag="AC1PIV_000075"
     CDS             73329..74060
                     /gene="xerD"
                     /locus_tag="AC1PIV_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HIP6611137.1"
                     /translation="MKQAIESFIQSKKVSVNSQKSYTYDLQQFVTVTKGEISQQSLLV
                     YQQSLLDLKPAAQKRKMSAVNQFLYFLYENNLLDRFYKLQTTSGPASVKKKLEREDLT
                     LLFQESPWLEGQLIALLIAYLGLTPSEIAELTSQQVNLDFQVLTVEKGGAKRVLTLPK
                     ELIPYMESHLSGRYVFDKKGQTYSRQWFFNRLTEFVQSIGKPDWTAQKLREQYILKQI
                     DEGKSLDQIAKQLGLKTSMSLEKFR"
     gene            74060..74779
                     /locus_tag="AC1PIV_000076"
     CDS             74060..74779
                     /locus_tag="AC1PIV_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HIP6611138.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQVDIYEVPITEVIEQYLAYIAT
                     LQAMRLEVAGEYMLMASQLMVIKSRRLLPKVVEQIDPEDDPEMDLLDQLEEYRKFKLL
                     SEKLGEQHDERANYFSKPKLDLIYDDVQLAKDKTVIDIFLAFSKVMAEKQASLRQSHA
                     TIARDEYKIEDMMDFVRSRFETGPRLELRQLFQESQDVNEMITIFLATLELVKVHEIV
                     LEQTETFGDIYLVRSEDESLS"
     gene            74763..75332
                     /gene="scpB"
                     /locus_tag="AC1PIV_000077"
     CDS             74763..75332
                     /gene="scpB"
                     /locus_tag="AC1PIV_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HIP6611139.1"
                     /translation="MNRLAEIEVLLFVAGEDGLTLRNLAEMLEMQPTAVSQQLEKLSE
                     KYMADKASGLAILESSNRYKLVTKKEYANLLRIYAKTPINQTMSRALLETLSIVAYKQ
                     PITRIEVDDIRGVNSSGAISKLQAFDLIRENGKKEVLGRPNLYVTTDYFLDYMGINSL
                     EELPDVSEIDLIQEETELFVERNELENEN"
     gene            75322..76053
                     /locus_tag="AC1PIV_000078"
     CDS             75322..76053
                     /locus_tag="AC1PIV_000078"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_function: GO:0140098 - catalytic activity, acting on
                     RNA [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HIP6611140.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELGTVIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVSDDKGRKTVVDLLPTVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYLARVKGVANKEVLRPLTRGVVIDGKKTKP
                     AVYEIIKVDPVKNRSVVELTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGNLDLTGLRP
                     GEYRKLNKKDISKLHTLAVTKPVKK"
     gene            76053..76292
                     /gene="yidD"
                     /locus_tag="AC1PIV_000079"
     CDS             76053..76292
                     /gene="yidD"
                     /locus_tag="AC1PIV_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HIP6611141.1"
                     /translation="MTRLLIGLVRFYQKFISPLFPPSCRYRPTCSAYMIEALQKHGLK
                     GFLMGLARIGRCHPLVEGGEDPVPDRFSLKRNKQK"
     gene            76861..77406
                     /locus_tag="AC1PIV_000080"
     CDS             76861..77406
                     /locus_tag="AC1PIV_000080"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001019793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0141098 - tRNA
                     (cytidine(34)-2'-O)-methyltransferase activity [Evidence
                     IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HIP6611142.1"
                     /translation="MNIETLEYIEETAKNHIVLFEPQIPQNTGNIARTCAATNSPLHI
                     IKPMGFPIDDRKMKRAGLDYWDKLDVRFYDNLAEFMDYASKQGRVHLVSKFADKTYSD
                     EDYNDGNIHYFLFGREDKGLPEDFMREHPEKAIRIPMNDEHVRSLNVSNTACMIVYEA
                     LRQQQFAGLDLVHTYDGDKLK"
     regulatory      77456..77670
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            77729..78286
                     /locus_tag="AC1PIV_000081"
     CDS             77729..78286
                     /locus_tag="AC1PIV_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HIP6611143.1"
                     /translation="MTNTRKMTIIAILSAVSFLLMYLKFPLIPTASFLEVDFSLVPIL
                     FGLLILDMKSSFAILLVRTFLKLILNNQGPSTIIGLPMNIAAMSVFILAVAYFWKNEQ
                     TLKNYLKAAAVATIGSTAVMLALNYVYAVPVYAAFANFDIKEILGLTNYLFMMVLPFN
                     LLQGIVLSAIFYICYKAAQPILKKV"
     gene            78311..78964
                     /locus_tag="AC1PIV_000082"
     CDS             78311..78964
                     /locus_tag="AC1PIV_000082"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA];
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HIP6611144.1"
                     /translation="MKNKQIHLRNASFFALAFVTLGYVVKFYPSTLAGFDSTVQSAIR
                     GNLPSGASQFWTSITVLGNTVIILAITMILAAIFYYYKKWKIEAYFLLASFAAMGVAS
                     TALKYVYQRPRPSIEWLIDTIGYSFPSWHTASTMMIGGAVVIIVHQRMKKGIARLVLQ
                     AMLILLAVLVAVSRIYIGVHYPTDIIGGWLLAVTLLQMMYPFYDQKRFEWRFQSKQK"
     gene            complement(79191..80990)
                     /locus_tag="AC1PIV_000083"
     CDS             complement(79191..80990)
                     /locus_tag="AC1PIV_000083"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HIP6611145.1"
                     /translation="MKIKWLSVIRVIGLVFVLLYHFFIKYFPGGFVGVDLFFTLSGYL
                     TTALLIDEFAKHKKIDIVSFFRRRFYRILPPLVLTILLVLPLALLVRNDFIANIGNQI
                     VAALGFMTNFFEILSGGSYENQFSPHLFVHTWTLAIEVQYYLVWAGLVWYRTRISKSV
                     GQLRGSIFLTSISLFSLSFLAMSISSFFVDNFSTIYYSSFTHTFPFFLGSILATIAGI
                     GNTTTAFQQQVNTLSIKQAIGLFLGGLGVELLLLFTLQFSSIWTYLIGFLLSSLATAT
                     MIFAARVLHEKTEDVKEPAIILFFASISYGIYLFHWPLLIIFTQLTNATIAAGLSFVF
                     STILSTISFYILEPYIAGKVGSLFGLAIDLKPYKKWLLSSFACLTIVGLGICLFGPKL
                     GSFEQESMVSNLYQAQTQLNTTRSAAENAKATSFEIQKGVIIFGDSVTVRASSAIQTA
                     LPDAQIDGTVSRNLSEIAKLINLYKQNNSLKETVVVALGTNTTDNYQELLDQLVKDFP
                     KGRRLIFVTPYDGNFTPSESISYQTGQYEKELAEKYDYISIADWYQVAKDNPPIWYNT
                     DLVHFNLESNGGEVFAQTIKNAVEAVADGPIKN"
     gene            complement(80980..81402)
                     /locus_tag="AC1PIV_000084"
     CDS             complement(80980..81402)
                     /locus_tag="AC1PIV_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611146.1"
                     /translation="MKEFKLPSIKWHDITSHFTRPKLEILSLIIILICALSVFTGRIA
                     SKQAMTFNNGALQYNGYVVANKMNGQGKLTFDNGDVYEGQFTNGIFHGQGTYTSASGW
                     VYTGQFKNGYADGKGKLTTEGQATYEGTFKQGIYQYEN"
BASE COUNT        23719 a        15366 c        18724 g        23685 t
ORIGIN      
        1 catcagcgaa aatgagattt cgagtaaaaa atgaaacaac atgaaaggat tacaaaaaca
       61 tgtcaaaaac tattcaggcc attactaatc agatttggtc catggccaat gaattgcgag
      121 gaaatatgga tgcttcggaa tataagaact atatcctagc cttcatgttc tatcgctatc
      181 tatctgagca tcaagagcgt ttcttggtgg aagatgaaat tatcagtcct gctccaggag
      241 aaactgttca ggatgcctat gcgcgagaag cagttgggaa tgacttggta gagcatttgg
      301 aaaatacagc ttctcacctt gggtatgcca tcgagcctga agatacctgg gcaagactgg
      361 tagccaaaat tgataacagt gagattgtag cgagtgacta ccagacgatt ttcgatcatt
      421 ttaacgccaa tgtagaactc aatcgggatg ctatggaaga tttcagaggc gtctttaatg
      481 acatcaatct aggggactct cgtttgggca attcaacggt tgtgcgtgca aaatccttga
      541 acagtattgt gaagttgatt gatagcattg agtataaaaa tgacgaagga aaggatattc
      601 tgggagaaat ctatgagtat cttattggac agtttgccgc ttcggcaggt aaaaaaggtg
      661 gagaatttta taccccgcat caagtgagta agattttagc caagattgtt actttaggtt
      721 tggaaaaatc agatactagc ttctctgttt acgatccaac catgggttca gggtctttgc
      781 tactaacagt gcgtaatgaa ctacctcagg gccagcatat caaattctat ggccaagaaa
      841 tgaacacaac tacttataac ttggcgcgga tgaacctgat gatgcatcag gtcggctaca
      901 gcaatatgat tttgaataat gctgatacct tagaaagtga ctggccggac ggggtggatg
      961 aacttggaat cgatcagcca cgtagttttg atgcggttgt tgcaaaccca ccctactctg
     1021 ctaaatggga caatcgtgag tccaaattga aggatccacg gtttatggaa tacggtaagt
     1081 tagcaccagc ttctaaagcg gactttgcct ttatcttaca cagtctttat catctgaata
     1141 atacagggac catggccatt gttttaccac acggagtgct ctttagggga gcagcagaag
     1201 gtcatattcg caaactgatt attgagaaaa attacctgga tgcagttatt ggcttgccag
     1261 ctaacctgtt ttatggcaca ggcattccaa ccactattct agtcttcaaa aaaaatcgtc
     1321 agaccaagga tgtcttcttt atcgatgcga gcaaggagtt tgagaaaggg aagaatcaga
     1381 atcacctttc cgatgacatg gtagaaaaaa ttgtagagac ctatcacaat cgtcagtctg
     1441 ttgacaaata tgctcatttg gcatcaatag aagaaattgt agaaaacgac tacaatctaa
     1501 atattcctcg ttacgtcgat acttttgagg aagaggaaga gattgatctc gggcaagtaa
     1561 cgcagcaact agaacaagat agactagaga ttcgggctct agaagataag attcgtcaac
     1621 aattaaagac tttgggagta gatttttaga taaatgaaaa gagcgagtag gatttttcct
     1681 cgctctttct ttgtatggct taaggtttaa tcacttctac cccacccatg tatggacgga
     1741 gaacttctgg aatggtgaca gaaccgtctt cattttgata gttttcaagg atggcagcca
     1801 ctgtacgacc aaccgctaga ccagaaccgt tgagggtgtg gagcaatttg actttaccgt
     1861 cagcagcatc gcggtagcgg atttgggcgc gacgagcttg gaaatcttct gtgttggaac
     1921 agcttgaaat ttcacggtag gcattttggg caggaatcca gacttccaag tcataggtct
     1981 tagcagctga gaagcccata tcgcctgtac agagggccaa aacgcggtaa ggcaagccta
     2041 gtttttggag aatattctct gcgtttgctg tcattttttc caattcatca taagactgtt
     2101 ctggtgtggc aaatttgacc atttcaacct tgtggaattg gtgaaggcgg ataagaccac
     2161 gggtgtcacg accggcagaa ccagcttcag aacggaaaga tgggctcatg gctgtgaagt
     2221 agattggcag gtctttttct tccagaatct cgttgcggta gtagttggtc aacggcactt
     2281 ccgcagttgg gatgaggacg aagttagtgt ctgccaactc aaaagtatct tccttgaact
     2341 taggatattg accagtacca aacatagagt cgtggttgac catgtaaggc gtgatgattt
     2401 cttggtagcc ttctgcgata tgctcgtcca acatgaagtt gtagagggca cgttctaagc
     2461 gagcacccaa gttcttgtag aagaggaagc gtgcaccagt tacttttgcg ccacgttccc
     2521 agtccagaat atctaggtct tcgcccaaat cccagtgagc ttttggctcg aaagtgaatt
     2581 cacgaggtgt tccccaacgg cgaacctcta cgttttcttc ttcatccgca ccaactggaa
     2641 cagaatcgtg cggcgtattt ggaagaacgg tgatgatggc gtttaattct tcatcgattt
     2701 ccaaaagctg agcgtctaag tttttcacat ccgcagacag tttctgcatg gcagcaatct
     2761 tgtcgtcagc gttttcctta ttgcgttttg cttgggcaat ctccgcagaa acggtgttgc
     2821 gctctgcttt taattcttct acagtaacca agatttcacg gcgttttgca tccaattcct
     2881 tgatgtttgc caaggtttca gcagccacac cacgagtagc taatttggca gccactccgt
     2941 caaaatcagt acgaatacgt ttgatatcta gcatagatgt ctcctttaga ataaaaaagc
     3001 acagaatgag agatgctgga gcgatattta ccgcggttcc atccagcttc acattctgtg
     3061 cacttgattg tattttgata atttcataac ggtagaattt cacaactttt tcctatctgc
     3121 tcacagcgac cgcagacttt ctggaaggag ccagatgcta cttatccgtt tctactatta
     3181 tacttgaatt tttatttttt ggcaaataga ttcgaaattt ttctgccgat tgtttgcata
     3241 agagtcggta atttcacaac tttttcattg ccgatatgct cacgggcaat tttaagaatc
     3301 ttaccagaat ctttagatgc aaacaagaat cgacttttct ctgtataaat ttcaaaatga
     3361 cggctgattg ctttgccaga aacgtttgcg ccaatgctag tcatttctga ccaaggaatc
     3421 tggatatagc gttcaacgtt gctatctggg tagaattcaa gtgccttgtc accaattaga
     3481 aatttaccaa ccttgccacc aaagcccatg taggaaaccc ctgtggtttg tagttcaacg
     3541 cttgtatttt gtgattgtgc catagtgctc tctccctaga tattcattat atcataaaac
     3601 cccgcaagag cggggtcctt gattacataa ttccgaagaa acgagcaaga atacctacga
     3661 tgaagagacc gataatcatt gtgattggtg ttactttctt cttaagcaag tgcatgcaga
     3721 ggaaagtaag gagaagtccc atcaaaccag gaatcaagct gtccaactga ccttgtaatg
     3781 tttgagcttg agttggttca aggctaagtc cgctaagagc ttgaccaaga atacctttca
     3841 actcagcacc agtaacagta ccttctggga agacgatgta agcaccttct gacaattgtt
     3901 tagcaggaag atctacagcg aaagtaatag atacccaacg ttgaacaaga acggcaagga
     3961 tgaacatacc aaggattgaa gcacctttag tgatgtcttg aaggatacca ccagacatgt
     4021 ctttagtgat ttcgctacca gctttgtaac caaattcttg tgtataccat aggaaggcca
     4081 tacgaatgat gttccagcca aggaagaaga tgattggtcc catgatattt ccagatagtg
     4141 caagtgaagc accaagagca ccaaggattg gacgaacagt aaaccagaag actgggtcac
     4201 cgataccagc aagaggtccc atcataccga ttttcacacc ttggatagct gtgtcatcga
     4261 tttcagcacc attagcacgc tcttcttcaa gggcaagagt tacaccaagg attggtgaag
     4321 caacgtatgg gtgtgtgttg aagaattcca agtggcgctc aagagcagca gcttgatctt
     4381 cttttttagt gtaaagtttt ttgatagctg ggatcattgc ataagcccaa cctaagtttt
     4441 gcatacgctc atagttccat gaaccttgaa ggaaggttga acgccaccaa acttttttac
     4501 gatcgcttac ggaaagttga attttttctg acatgatgaa tctcccttct cttagtagtc
     4561 ttcaaggatg tcgccgattg ggtcgttaga tgaagcacca ccgttacctg atccgccttg
     4621 ttttgacaag ttgaggtaga taagagcgat tgcaacaccg ataacaccaa gtgcgataag
     4681 tgtcaatttg ctgatagcag caaatgcaaa accaagtgcg aagaatggcc atacttcacg
     4741 agttgccatc atgttgataa ccatagcata acctacggca acaaccatac caccaccaac
     4801 ggccatacca cctgacaacc aagctggcat agattcaaga actgcttgaa cagcttctgc
     4861 aggaattgca agaagaagag ccgcaggaac tgcgatacgc aaaccttgaa ggagaagagc
     4921 aaacaagtgg taacgttcta cagcagcgaa gtttgcatct ttagcagcat tgtcagcacc
     4981 gtgtacaaga ccgactgaga tagtacgaac gatcattgta aggaaaagac cagctacggc
     5041 aagagggata gcagttgttg ttgcaacggc aataccttca gttgagaagt cgccaccttt
     5101 gatcatgatg attgcagcag ctacagaagc aagagcagcg tcaggtgcaa cagctgcacc
     5161 aatgtttgcc caaccaagtg caatcatttg tagagaacca ccaagcataa cacctgcagc
     5221 caagttacca gtcacaagac cgataagggt acaagctacc aatggttgat ggaattggaa
     5281 ttcgtcaagg ataccttcaa gaccagcgaa gaaggcaacg atgacaacga gaattgcaga
     5341 aataagtgta atatctgaca tgttgtaatc ctttctatac taacagatcg atttattgaa
     5401 cgtttgcctt gttgataagt tcaaacaagt ctttcttcga atcgtttggt actttacgca
     5461 catcaaattc aacgccaagg tcacgcaatt tttcaaaggt tgcaacgtca tctttgtcca
     5521 ttgacaatac gttgttaacc attgttttac cagttgagtg agccatagaa ccaacgttca
     5581 attctttgat ttcaacacca ccttcaattg cttcaagagc ttcttgagga gtttcgaaaa
     5641 gaatcaaggc gtgtgtgtta ccgaatcgag ggtctttaga aacctcaatc aatttcttga
     5701 ttgggacaac gttcgctttt acgttaccag gtgcagcttg tttgatgagt tgtttgcgca
     5761 attcatcttt ggcaactgta tctgatgcaa cgatgatacg atctgctttg gaagcaggag
     5821 tccaaccagt cgccacttga ccgtgcaaga gacgagtgtc gatacgggct aagttgattt
     5881 tcaacttgcc atcaccgata acagtacctg gagggatagc accttgtagt gcaacaggag
     5941 cagcatcggc aacaggagca gcttcagctg gttgaagttc ttctggaaga actttgatac
     6001 catctttggc ttccttgata atgtttgccg caacttcttc cacgccagca gcagcgttaa
     6061 tcatacgctc tgtgtaagct tggataagca ttggcaagtt tagaccggtg atgatagcaa
     6121 acttacgatc tggattttca ccagctacac ggcttgcttg gttgaatggt gaaccactcc
     6181 aaaggtcagc caaaaccaaa acttcatcat cggcatcgaa tgcgtccacg gcagcattta
     6241 gcttagcgta taaatcatct ggaccttcac ttggcataaa agtaacaact tgtacttttt
     6301 cttgttcgcc aaagatcatt gaacctgact gatgaatacc agcagcaaat tcgccatgac
     6361 ttgcaataat gattccaata ctcattattg atcctcctaa atttttcttg ttcatgtaaa
     6421 aaccattgaa tgggctttca tgttcgaact gtaccattat aaaacgtttt cagtacattt
     6481 gtcaagtagg tttgtgttaa aagtgcaaaa tatttccgaa acttttgata atcgtgtttc
     6541 agaaaagtga taaaaatatg caacgaatat gacaaaaacc tgatagttta tcaggttttt
     6601 tgatgtctat aaaaataggt tttctagttc acgtgcgaca ccatcttcaa aattagcaaa
     6661 tgctgtcaat ctgtcggcat gcggacgaag tgtatcgcta caatttttca tggcataggc
     6721 tgttcctgct aggtctagca tctcaacatc gttgtgctca tcgccgaagg caattaagtc
     6781 gctaggagag gcttggtaga ggttaagaac atagctcaga gcggttgcct tattgacgcc
     6841 ttttgcacaa gtttcgagga tatttaatgg tccgccccac gtattgattt ctaattcatc
     6901 tttgaaatag gcattcattt cttttgcaag ttcatactta tcagttgcac gagtctgcat
     6961 aaggatggaa tgaggatcac tagtgattaa ttcaggtttg atgagtgtat caggagtaat
     7021 ctgttcaact cccatcagag caggatcaat cttgtctaag ttcttttgag tgatgtagaa
     7081 tttattcttg tattcaccag caataaaatc tgcctcgaat gtttcttctt cttttagaaa
     7141 ttcgagtagg tattttttgt cgattaaaat attttgttcc cattgccatt tctttccagg
     7201 gatgtgaact aaagaaccgt tgaaattaat catgggagta tccagttcta gttgttggta
     7261 aaatttttca gccattcgat aggggcgacc tgtggcgata agaacggtgt gtcctgcttg
     7321 gcggaccttc tttatagttg agatggtata atcagataat tggctatcat tattgagcaa
     7381 tgtgccgtcc aaatcgatag ctatgatttt tttcttcata tttaatagca ttcctttcta
     7441 gagttgttat actagttttt aatagtgaat aatgtttagg tagtagttag agtgctgaga
     7501 aattgtttta tgcgtcaaag aatagtactt gtaggtagcc acatcttgaa ctaataactt
     7561 ccagtataac aaaaggagat aataaaagca aagaagcaag taattttgta tagatttttg
     7621 caagattgca acgttcggaa tttacgaatg tttaaagttg aaaattaata aaataacgtt
     7681 ttcaagatta aaaaacttga aattataatg ttttttgatt ataatgtttt tattgttcgt
     7741 aaattaaaag gagagatgaa aaaatggatc aattttttaa attgaaagaa catggaacga
     7801 ctgtttctac ggaaattatg gcaggactta cgactttctt tgccatgtcc tatattttgt
     7861 tcgttaaccc gagcgtattg agtgtggcag gtatgccaac acaggctgtt ttcttggcta
     7921 caataattgc cagtgctgta tcaacgcttg ttatgggatt atttgctaac gtaccttacg
     7981 ccttggcacc aggtatgggg ttgaatgcct tctttaccta tacagtggtt attggtcttg
     8041 gttttacttg gcaagaagct ttggcaatgg ttttcctctg cggtttgttt aacgttttta
     8101 tcacagttac aaaggttcgt aagagtatta tcaaggcgat tccagttagt ttacaacatg
     8161 ccatcggtgg tggtatcggt gtattcgttg cctatcttgg ttttaaaaac tctaatttaa
     8221 tcaccttctt gacatctggt tcagatatta ttactgtaaa tggtgttgct ccggcagatg
     8281 caacagcaga aacattctca aacggtgttt tctcagtttt tgctggtggt ggtgtcgtac
     8341 ctggtatttc aacctttact gatccaagtg ttctcttgac agtgttcggt cttcttttga
     8401 cagctgtttt ggttattaag aacgtgcgtg gtgcaatttt gattggtatt attgcaacga
     8461 ctgtagctgg aattccagca ggtgttgtgg atctgtctac aatcgatttt gcaaataaca
     8521 ataccggtac agcctttgcg gagcttggta caactttcct agcggctttt gatggtctat
     8581 cttcgctctt tgctgactca agccgtctac cacttgtttt gatgactatc tttgcattca
     8641 gcttgtcaga tacctttgat acacttggta cctttatcgg tacaggtcgt aagactggta
     8701 ttttctcaga agaagatgaa aaagctctcg aaaatggtac aggctttaac tctaagatgg
     8761 acaaggcgct ctttgcagat gcgattggta cctctatcgg tgcactattt ggtacgtcaa
     8821 atacaacgac atatgttgaa tcggctgcag gtatctctgc aggtggtcgt actggtctga
     8881 cagctgttac aactgccgtt ctcttcttgc tatcaatttt gattttacca ttcattggaa
     8941 ttgtgccaaa tgctgcaaca gctccagcct tgattatcat cggtgtcatg atggtttcat
     9001 ccttccttga tgttgattgg agccactttg aagatgcgct tccagccttc tttgccgcct
     9061 tcttcatggc gctttgcttc tctatctctt acggtattgc agccgccttt atcttctatt
     9121 gcttggtaaa agtttcgaca ggtaaggcta aagaaattca tccaatcctt tggggtgcca
     9181 cagctctatt tattctgaat ttcatcattc tagccatctt gtaatctgtt tattatcctt
     9241 gaactgatct tcatttgaag gtcagttttt ttatttacga ttaaaatata tgggaatcaa
     9301 tgtgatttat tcagcataat gctgtattga agattgtaaa ttgaaaacgg atggagttta
     9361 tttttccatt tcgtcgcttc tctgtctcct cttagtgcca tttttactcc ttgtgactgt
     9421 attttaaatg gctgttcgtt attgtaagca agatgtctca tacctagaca tccgctggat
     9481 taatgtcatg atggggtgaa aaatttatca tgtagtcttt gggagtcaca gggcatagaa
     9541 taacccctga gcttgggctc agggggagtt ttctaactat aatgtttgaa tagcgaatga
     9601 gttgcctgat ggatggtgcg tgctgtttca gcgttgttca tagtgtagag atggatacca
     9661 gccacatcat tggtcactaa gtcaacaatt tgatctacag cataggccag acctgctgcc
     9721 cgaagagatt caggattgtg ctcgtatttt tccaagatgg ccttgaattt acgagggagg
     9781 cggatattct cacaggtttt caagagtcga agtgcctgat tcttgttgat aataggcata
     9841 atacctgcga taataggcac ttcgatgtct gctagagaac atttctcctg aaagttataa
     9901 aatgcttcgt tatcgaagaa gagttgagtt accaaggttg agcaaccggc atcaactttc
     9961 tttttcaaat ttttgatgtc tgagacagaa tttggtgatt ctggatgtac ttctggataa
    10021 caggctccaa taatgtcaaa atgtggggct tcttccttga taaaggaaat caagtcagtt
    10081 gcatactgaa agtcctcttt agggggaaga ccttcaataa tatcgccacg aagtgctaaa
    10141 atctgatgta caccaatttc atcgagagaa tgaagaacgg atcggacctt ttcttttgtc
    10201 aagtaagcag ctggcaaatg tgcgatagtt ggaatatgca attcattgcg aacatggtta
    10261 gccaacttga cagtagtctc ttctacgttc aaattgttat tgctgcatgt aacactgata
    10321 aaatgagggg ccaaaccttg catctcatcg agagtttgga taatcttttc attgcctact
    10381 gctggttttg gaggaaaaat ttcaaatgag agacttgggg tttgaccaat cataaattag
    10441 agttcctttc tggctgcctt agctgcttga gtcaagtgga taagactagc ttttgtttct
    10501 gattcgccac gagtcttgag tccgcagtct gggttaatcc aaactttttc tttcggtact
    10561 ttagcaagga tggcttgaat agtgtgtgca atttcatcaa cggcagggac acgtggcgag
    10621 tggatgtcat agacaccagg acctacctga gtttggaagt tcttagcctt aagttcatct
    10681 aggataacaa gatttgaacg gctggcttca aaggagataa cgtccgcatc catattgtcg
    10741 atggcaggaa tgatgtcagt aaattcgcta tagcacatgt gggtgtgaat ttgtgtatct
    10801 ggtgcaacag ttgagtgtac taaacggaag gcagggattg cccaatcaag atactcgctg
    10861 taccagtcgc tacgacggag tggtagtttt tcacgaaggg ctgcttcgtc gatttggata
    10921 atcttgatac ccgctgcttc aaggtcaaga acttcttcct tgatagcaag agcaatttga
    10981 agggttgatt ctttgataga aatatcttcg cgtgggaatg accagttgag gatggttaca
    11041 ggacctgtca acataccttt aactggtttg ttggtacggc tttgagcata gctagaccat
    11101 ttgacagtaa ttgggttcaa gcgtgttaca tcaccccaga taattggtgg tttaactcca
    11161 cgcataccgt aggattgtac ccaaccgttt ttactgaaga ggtagccaga caggttttca
    11221 ccgaagtatt ctaccatgtc gttacgctcg aattcaccgt gtacaagtac gtcgaagtca
    11281 acttcttctt gccatgcaat ccactcatct gtttgagttt tgacaaatgc atcgtattct
    11341 tcttctgaga tgtttccttt gcgaaaggcc aagcgtgtgc tacggacttc cttggtttga
    11401 gggaaggaac cgatagtggt tgttggaaga agtggtaagt ttagcttctc gcgttgaatg
    11461 gattcacgct ctgcaaagac tggtaggcgt gtatagtcag tgtctgtcag tcctgcaaga
    11521 cggtctgcaa gggctgcatc acgaccaaca cgctcaaggg caaagagttc cttgttagct
    11581 gtgagagcaa cttcgccttg accgttacgg atggcatcca aatcacgcaa ttcgctcagt
    11641 ttttcaactg caaaggcaaa gtggttgagg atagctggtt caaattcttc atttgctgtt
    11701 gtgaaaggta catgaagaag ggagcaagaa gttgttataa cgacattttc agctggaata
    11761 gcatccaaaa cagccaggct cttttcgtag ttgttgcgcc agatattttt accgttgacg
    11821 ataccagcgt agagggtctt gtcagcaggg aaaccagttg caacaagtgc agccgtttcc
    11881 ttgccttcta caaagtcaag accgatggca tcaactggta ggctggtcaa ttctgtgtaa
    11941 atatcacgaa catcaccgaa gtaggtttgg atgagaactt gcaaaccttt cttatctgcc
    12001 aagagtgttt ggtagatacg taggaaaagg gctttttctt cagcagtcaa atccttgacc
    12061 aagctaggtt cgtccagctg gattttttca gcaccaagct ctgctaattt ttcaaagact
    12121 tgtccgtagg ctgcaactaa gctatcagcg aaattagtag cagttaaacc ttcttcaaaa
    12181 tcagttaatt gtaagagtgt gaatggacca atcaaaactg gacgagttgt gatgcccaag
    12241 ttctttgctt cttggaattc atcgaaaatc ttatgaccgg ctagtttgat ttctgtatct
    12301 ttttcaatag ctggaacgat atagtggtag ttggtgttga accatttttt catcggtcta
    12361 gcacgaacgt cccctttttc tccttgataa ccacgtgcaa gagcgaagta tttttcaagg
    12421 tctgttaatt caaggtcttg aacagctttg ggtatgatgt tgaagagtac tgccgcatcc
    12481 aaaacattgt catagtgtga gaagtcgttg cttgggattt cagtaatgcc tgcttcttta
    12541 acaatattcc agtgcttagc acgtaagtct ttagctgctt ccaaaagctc ttcttgtgga
    12601 atttcatttc taaagtattt ttcagtgata aattttaact cacggtgttc tccgatacgt
    12661 gggaagccga taatagtagt agtcatggtt tttcctccaa aatatttcta tgcccctatc
    12721 ctaacagaaa aaacgactct tgtataattg taaaaaatta gagggagtta taacttttga
    12781 ctataacaga ttgaaagaga gctacttttt tgatatttct tctatataaa agcttgaaaa
    12841 aaagcctgtt tatcaagctt gactttttta tgctggctcc agtatagttt tttcttaagc
    12901 gtggtataga ttttatctat gaaactgcta aaggcaaact cttgtttatg agcaattgtt
    12961 tataggtagt tctgatagtt attttttatc aagccataaa acttctatat tagacagggc
    13021 tagatagcca tgctacaatt gaaaaaatga aagaaagggg ctttttatgg gaaaagttat
    13081 cattggaatt tcaggaaacg agcaagaatt tccaacaaaa tctggtcgcg tatatgtaac
    13141 ggtagcgcgt gaattggcag acagcgttcg tcaggctggt ggtgtaccaa tggttattcc
    13201 tatgggaact cctgacttag ccaaggatta tatcgatatg attgacaagt tgatcttgtc
    13261 aggtggtcag catgtggatc caagtctcta cggtcaaaaa cgcttgattg atagtaatga
    13321 ttacctcttg gaacgggatg aatttgaact ggctttgatt gaggaagccc ttcatcaggg
    13381 aaaaccgatt tttgcagtct gccgagggat gcagttgctg aatgttgctc taggtggaag
    13441 cttggaacaa gaggtggatc atcattggca agatggtatt gctgggacat cccatcgttt
    13501 acaagtgaaa cctaaaagcc gaatcggtca attgtttgcc caagggagcc ctattaattc
    13561 cttccatcag caacgaatca aagaattggc tccaggactg gtggcgacag gtttggatcc
    13621 tagagatggt acgatagaag cttatgaaag tagagggaac caagctttgt ttggtatcca
    13681 atggcatcca gaatttttat acaatgattg taagcaacat cgagacctat ttcagtattt
    13741 agtagatata ttttaagagg ggtatccctc tttttattat caatacttat aattgcaagg
    13801 gtatttgtta taacgaaaag ttataacttt ctataaaaaa agtcaattag tcagaaagaa
    13861 aattctgtgt taagatagat acagttaatt taaggagatc attttatgaa attaaaaaaa
    13921 ttgtttagtt tggcaacggc tgctttatca gtaggtgtac ttgctgcatg tggtaactct
    13981 tcttcaagtt cagattcatc tgcaacaact gttcgagtag gtgtgatgag cttgagcgat
    14041 tctgagcaag cccgttggga taaagttcaa gaaattcttg gtgatgaagt gaaattggag
    14101 ttcactcaat ttacagatta ctcacagcca aacaaggcag tagctgaaaa cgaagtagac
    14161 atcaacgcct tccagcacta taacttcttg aataactgga atcaagaaaa tggtgaagac
    14221 ttggttgcta ttgcggatac ttatatcgca ccaatccgtc tttactcagg tacagctgat
    14281 ggaaaaaaca agtacactaa agtggaagaa attccagatg gtgcagaaat tgcggttcca
    14341 aacgacccaa caaacgaaag tcgtgctctc taccttcttc aagcagctgg tttgatcaag
    14401 gttggtgtat ctggtacaga attggcaact attgctgaca ttactgaaaa caagaaaaac
    14461 ttgaagatca ctgagttgga tgcaagccaa acagcaagct cacttagctc agttgatgca
    14521 gcagttgtaa acaacacatt tgtgttggaa gctggtttgg attacaaaaa tgccctttac
    14581 aaagagcaaa aagatgaaaa ttcaaaacag tggtacaact tgattgcagc tcgtagcgat
    14641 tgggaaaaat cagagcaagc agcagcgatt aagaaaatta tcgaagccta ccacacggat
    14701 gaagtgaaaa aagttattga agagacttca gacggtatgg atgagccagt ttggtaaaat
    14761 gtaaataggt tgaggactgg gcagaattgt tcagccctct atctgttttt atagagataa
    14821 gaaaaaatct cttaaccaaa gtcagaaatg tgggagaata tttgattttg gttagtagat
    14881 ttaattggtt ttcattgagt atgaggagaa agtatggcag atagtaaagt tcaagcattt
    14941 gaaaatgatg cgattattca aacctatttt gaaaagttga aggtcttgat ttcaaagaaa
    15001 tccatttttg ctcagcagat tggtttgctg gatgtggcga cttacttgaa agatatattt
    15061 gaagaagctg gtgcagaggt tgttttggat gatagttatg cagcaccctt tgtcatggct
    15121 aggtttgagg cttcggttcc agatgcgaaa acattgattt tctacaatca ttatgataca
    15181 gtacctgcag atgccgatca ggtctgggag aagggcaacc ccttcgaatt gaccatttcc
    15241 gatggctata tctatggtcg cggggtagat gatgataagg gccatatcac agctcgtctg
    15301 tcggccttga aaaaatatca agctagacag aatggccatt taccagtcaa tgtgattttt
    15361 attatggaag gggcagaaga gtcagcctct gtcgacttgg ataagtatct ttcaaaatat
    15421 aaagaacatt tgattggtgc tgatttgctt gtctgggagc aggggcatcg caatagccta
    15481 catcagctag aaattgctgg tgggaataag ggaattgtga ccttcgatct tcaggtcaaa
    15541 tcagctgact tggatattca ttcttcctat ggtggtgtca ttgattcggc aagctggtat
    15601 ttattatcag cacttcaatc catgcgggct gcagatgggc aaattctggt agaaggcatt
    15661 tacgatcagg ttcaagagcc aaatgagcgt gaattggcct tggtggaaga atttgcactg
    15721 gctaccagtc agtctatgac ggatatttat ggactaaccc ttccaacctt gatagaagat
    15781 cgtcgtgagt ttctgaagcg tttgtatttt gaaccatcga ttaccattca aggcttgtca
    15841 actggctatc ttggtcaagg tgtcaagacc atcataccag ctcaggcttc tgctaagatg
    15901 gaagtccgtc tggtacctgg attggagccg catgatgtat tagataagat tcgccagcat
    15961 ttggataaac atggttttga caaagttgag gttgtcttca ctctaggaga gatgagctac
    16021 cgaagtgaca tgtcccaccc tgccattgtc aatgtgattg agttggctaa aaagttgacg
    16081 ccagaaggag ttgctgtttt gccgacgtca ccggggacag gacccatgca tacagttttt
    16141 catgccttgg gcgtgccgat tgcaggattt ggattaggaa atgccaacag tcgcgaccat
    16201 gcaggtgatg aaaatgtcag catcgctgac tactatagcc atgttgaatt agtagaggag
    16261 ttaattgcaa gttatgagta aggaaatgat taagctagat aatattgatg taactttcca
    16321 gcagaaaaaa cgtacgattg aagcggtaaa ggatgtgacc atccatatca atcaagggga
    16381 tatttacggt atcgtaggtt attctggagc agggaaatct acccttgttc gagtgattaa
    16441 tttattgcag gtgccgacag cgggtaaaat tactatcgat gaggatgtaa tttacgaggg
    16501 agaaaaggtc acacttaccc cagctcaatt gcggagcaaa cgccgtgaaa tcggcatgat
    16561 tttccagcat ttcaatctga tggctcaaat gacggcagaa gaaaacgtag cctttgccct
    16621 taagcattcg ggtttgagca aggaagagaa gaaagaaaaa gttgctaagt tgttggactt
    16681 ggttgggctt tctgaccgtg ctgaaaacta tccagctcag ttgtctggtg gtcaaaaaca
    16741 acgtgttgcc attgcccgtg ccttggccaa tgaccctaaa atcttgattt cagatgagtc
    16801 aacttctgcc ttggatccga aaacaactaa gcagattttg gcacttttgc aggaattgaa
    16861 tgaaaaattg ggcttgacca ttgttatgat tactcatgag atgcagattg taaaagatat
    16921 ttgtaaccgt gtggctgtta tgcaggatgg tcgcttgatc gaagaaggtt cagttttaga
    16981 aatcttctct catccaaaag aagaattgac acaggatttc atcaaaacag caacaggaat
    17041 tgatgaggcc ttggtgaaaa tttaccagca ggatattgtt aagaatttgc ctgagaacag
    17101 tattttggtg caactcaagt acgcaggttc aaatacggat acggcaattg tgaatgactt
    17161 gtataaattc tatcaagtat ctgccaatat tctttatggc aatattgaaa ttttggacca
    17221 tacgccagtc ggtgagatgg tggtgatctt atcaggtgaa cctggtcagt tgcaccgtgc
    17281 gattgaagca gtgacggaag cgcgtgtgga agtgacgatt ttgaaaggag cgaactagat
    17341 gttagaatgg attcaaacga attttccaga tatttataaa ttgggctggg atggtcagac
    17401 aggttggtta acacatttta atttgaccct ctatatgacc tttgtttcct ttgcttttgg
    17461 tggatttatg ggcttggtgt ctggtttgtt cttggtcttg acaggtccac gtggggttat
    17521 tgccaataag actgcctatt ggattttgga caaggtggct tctatcttcc gtgccattcc
    17581 ttttattatc ttgttggcgg ctattgctcc tttgacgaaa attattgttg gaaaaaccat
    17641 tggtacagag gcggctttgg tgccgctcgc tctttcagtc tttccgttct ttgcccgtca
    17701 ggttgaagtg gttttatcag aattggatcg tggtgtcatt gaggcggctc aggcatcagg
    17761 tgcgactttc tgggatattg tccttgtcta tctgcgtgag ggtctgcctg acttgattcg
    17821 tgtgacgaca tttgccctgg tttccttggt cggctataca gccatggcag gagctatcgg
    17881 agcaggtggt ttgggacagg ttgcgctatc atacggctac ctacggtata ataatgatgt
    17941 gaccttttta gcaactcttt tgattttagt tatcatcttc gtaatccagt ttattggaga
    18001 tttcttgacg agaaagatta gtcatagata gttatttagt tgtgtttttt caaattttgg
    18061 atagtccttg acttatttaa agcattttta tacaataaat ttaattaaat aaacactgcc
    18121 accgggtagt catgcaacag cattttatga acgtcgttag gtcttagaag atgttcatag
    18181 ggtgctgatt tttctataaa aggagtgaga atatgtcaca atttgttgtt gattcatctt
    18241 tttggagtct atttccagat gcaaaaattg gagttctatt attgaaagat tataaaacgc
    18301 cggcgcaatc gcctgatgaa ttagtgaaat tactggaaga aagcaacgga attgcccaga
    18361 aatttcttac ggaagatacc tttagtgaga atgaggtcat tcgtacatat cgtcaagcct
    18421 atcaaaaatt taaaacaaaa aaaggcgcgc gttctagtat cgaagcactt ttgaaacgtt
    18481 caactagtga ccgtccagtc acaacaattt ctccattagt ggacatttat aatgcggcga
    18541 gtttacgttt tggtcttcca tgtggtgctg aagatttaga tacatttgta ggcaatctcc
    18601 aactaacggt cactgagggt ggggatgaat tctatctcat tggtgatgaa accaataatc
    18661 caactttacc aggtgaagtt tgctataagg atgataaagg cgccgtttgt cgctgtttca
    18721 attggcgcga tggtgagcga accatgatta cggatgagac aaagaatgct ttcttggtca
    18781 tggagttggt caattctgat agagtagaag atttggaaaa tgccctagat tttatcagtc
    18841 aacacgcaga aaaattcttg ggagtagtac cagaaaaata tctactagat tgcgataggc
    18901 ctgcaatagc cttgtaggat ttgtcagcgg gattgtgttc ggataaatag tggtctttct
    18961 agacaaatgc tgatttttct gctacaatac taagcatgaa agaaggttgt ttcaaaagcc
    19021 tgtctagcga gcttgggaga gtgaaagcca agccagtctt gaaataattg gcgctttccc
    19081 agtcgtgacc atgtccgact caatcagaat catacaaatg aagtaataaa ttagggtgga
    19141 accgcgttct caacgcccct atgtctgttg acaggggaag agaatgcggt tctttttgtc
    19201 tgccgaccga gtatttcttg tttttcatct caaggtgaaa gacagctatt ataaagaaag
    19261 gagaccaatg ttcaccttag aaaatatcaa tcacgggcat gaacagttta cagggcctga
    19321 ttttcccaaa ctgattgcct attttaagga cttgggtatg gtggaaaata ttgtggatat
    19381 ccagtctggc caggttacct atcgctcaca gacagggcaa actctggaaa agcagggcta
    19441 tcaagtgacg atacctgttt cggaccaagc caatctggac cagtttgtga ctatcttacg
    19501 caatcatcag gctggacaaa cagattttct caccttctgc caagaaacag cagaagcagg
    19561 gatttacaag tgggtcatcg atctagaagc catgacctgt tcctatatgg acaaggcaga
    19621 acaggctgtc tttgtggaaa ctataccgag tgtggagaac tagccatttt gcaatatata
    19681 tagaaagagg ctgttatgtc aaagaaactt acttttcaca gcgccagtgg catagtctcc
    19741 tttcagtcga attgccacac gctcatcgct atggcggctg agctagacgc tgtactagtt
    19801 cgcctttcct agcggtatcg gctaggaagg ctcacgtcgc aaaaacatcg tcatttagtt
    19861 tatcttttat tacgtcgtta actcgctttg ccgtacctca gtactgcctg cagcttgttg
    19921 cctagtacta aaagtaaact aaaagactta gatttaaaga aagaaggaaa aatatgtcaa
    19981 aaaaacttac tttccaggaa attatcctga ccttacaaca attttggaat gagcaggggt
    20041 gcttgctcat gcaggcttat gatacagaaa aaggtgcggg tactatgagt ccatacactt
    20101 tcttgcgtgc tatcgggcct gagccttgga atgcggctta tgtagagcct tcacgtcgtc
    20161 cagcagatgg tcgttatggg gaaaacccaa accgcttgta tcagcaccac caattccaag
    20221 tggttatgaa accatctcca tctaatatcc aagaacttta cttggaatct ttggagcgtt
    20281 tgggtatcaa tcctttggaa catgacattc gtttcgttga ggataactgg gaaaaccctt
    20341 caacaggctc agctggtctg ggctgggaag tttggttgga cggtatggaa atcacgcagt
    20401 ttacctattt ccaacaggtt ggtggtttgg caacaggccc tgttacagcc gaggtaacct
    20461 acggtttgga gcgtttggct tcctatatcc aagaagttga ctccgtttac gatatcgaat
    20521 gggctgacgg tgttaaatac ggtgaaatct ttatccagcc agaatatgag cattcaaaat
    20581 actcctttga agtatccgac caagacatgc tccttgaaaa cttcactaag tttgaaaaag
    20641 aagctgagcg ggctttggaa gaaggattgg ttcacccagc ctttgactat gtactcaaat
    20701 gttcccatac ctttaacctg ctcgatgccc gtggagccgt atctgtaacc gagcgtgctg
    20761 gctacatcgc ccgtatccgt aaccttgccc gtgtcgttgc caagaccttt gtggcagagc
    20821 ggaaaaaact cggtttccca cttttggatg aagcaacacg agcagaattg ttgaaggagg
    20881 acgcagaata atgacaaaga atttacttgt tgaacttggc ttggaagaaa ttcctgccta
    20941 catcgtaacc ccagccatgc accagttgcg tgaccgcatg gcgacctttt tgacagacaa
    21001 tcgcttggct tttgacagca ttgatgtctt ttcaacgcca cgccgtttgg ctgttcgtgt
    21061 gcgtggtttg gcagaccagc agactgatct tacagaagat ttcaagggtc ctgctaagaa
    21121 gattgcctta gacgcagacg gaaacttcac caaggctgct gaaggttttg tccgtggcaa
    21181 aggcttgacg acagctgaca ttgaattccg cgagatcaag ggcgaagagt atgtttatgt
    21241 gaccaaacac gaagcaggcc agccagctaa gacagttttg gcgggcattc cagaggtctt
    21301 gaaggctatg accttccctg tcagcatgaa ctgggcgtcc aacaaattcg cctacatccg
    21361 tcctgtccac accttgaccg ttcttttgga cgatgaagca ttggatatgg acttcttgga
    21421 cattacatct ggtcgcatca gccgtggtca ccgtttcctt ggaaatgaaa ctgagattgc
    21481 aagtgcagat tcttacgagg cagacttgcg tgcacagttt gttatcactg accccgcaga
    21541 gcgtcaaaat atgatcgtcg agcaaatcaa ggctatcgag gacaaacaca acgtgacagt
    21601 tgaaattgat gaagatttgc tcaacgaagt tctcaatctg gtcgagtacc caactgcctt
    21661 catgggttct tttgacacta aatatttgga agtaccagaa gaagttttgg taacttccat
    21721 gaaaaaccac cagcgttact ttgtagtgcg ggataaggct ggcaagcttt tgccaaactt
    21781 catctccgtc cgaaacggta atgaccagta ccttgacaat gtcattaaag gaaacgaaaa
    21841 agtcttggtg gcccgtttgg aagatggtga gttcttctgg cgtgaggacc aaaaactcaa
    21901 gattgctgac ttggtagagc gactcaaagt tgtgaccttc catgagaaaa tcggctcact
    21961 ttacgagcac atggaacgca ccaaagttat cgcagaaaaa ctggctgact tggcaggttt
    22021 gtctgcgggt gaaaaagcag atgtggcgcg tgcggcggac atctacaaat ttgacctctt
    22081 gacaggcatg gtcggtgagt ttgatgaatt gcaagggatt atgggtgaga agtatgccct
    22141 tcttgcaggg gaaaaacctg cggtggcagc ggcaatccgt gagcactact tgccaaactc
    22201 agcagaaggc gaattgcctg agagcaaggt cggtgcggtc ctggcactgg ctgataagtt
    22261 tgacaccctc ctatccttct tctcagttgg cttgattccg tctggttcaa acgaccctta
    22321 cgctcttcgt cgtgcaacac agggtatcgt gcggattttg gaagcatttg gttgggaaat
    22381 tccattggat cagttgattg cggagctcta cagcttgaat tttgctagct tgacctatga
    22441 caaccagcca gctgttatgg actttatccg tgctcgtgta gagaagatga tggacaagac
    22501 cattccgaaa gacatccgcg aggctgtact tgccagctca acttttgtgg tcagactgca
    22561 actggcagcc agctctgcta ttttccaaaa agcaaaagag gctgactaca aggaagccgt
    22621 ggaaaacttg tcacgtgtct tcaacttggc tgaaaaggcg gaggtgactg cgattgacga
    22681 ggccctcttc gaaaacgacc aggaaaaagc ccttgctgct gcagtggcag gcttggagtt
    22741 gacagaagat atggcgggca acttggacaa gctctttgct ctcagcccag tcatcgcggc
    22801 cttcttcgac aataccatgg ttatggtaga tgacgcaaca gtcaaagcaa accgcttggc
    22861 tctcttgaaa gccttggcgg ataaggcaag tgctgtggcg gtcttcaatc tcttgaatag
    22921 caagtaggag gcatttatgg aacaagcaaa aatcgatcgc atcaatgaat tggcccgcaa
    22981 gaaaaaggcg gaaggcttga cagaggagga gttgcaggaa caagcagctc ttcgtgagga
    23041 gtacatcgag ggctaccgcc gtagtgtgcg tgcccacatc gaaggtatca aggtcgtcga
    23101 tgaagacggc aatgatgtga cgccagagaa actccgtcaa gtccaacgtg aaaaaggttt
    23161 gcatggccgt agtttggatg atccaaattc ctaagaataa atgataataa acaaggaaag
    23221 actaggtttt ctagtctttt tttgtgcttg cagcctactt acaataacga atcactcgag
    23281 atatagtcat ttgaattagc tttgatacat cgtcactttc agcttgccat actctacgaa
    23341 agtgacttgt ttcgcaagtc ttatttccaa gctagaacag cctagaggtt gttctaacta
    23401 cctgcacctc agttccttgt ctaaaagctc tttatttgac tatagcaaag ccttgaaaaa
    23461 atctctggct cagactaaaa aatgctaccc aacagcccgc tctaggctga tgagcaggat
    23521 tattatagcc cgctcttgac agaagttgag ttagaaagtc aattgccata gtagattatt
    23581 ttgacttgta tttacgataa aatttatgtt aaaataggga cggaaacaaa tagataggga
    23641 ggttggtcat gaaaaaactg gtgtatgcct tgttggtgct tgcctatgtt acggtcgctt
    23701 atttgtcggt ctatgtcctt ccacactatt attctggtgc aattatagga gcggcaggag
    23761 caagtcttgg tgctagtttc aaacagttca aggaagtgaa agcttctcct gataaagcct
    23821 tattggctta ttttaagagg gatgagaaaa aggcaagtag tttattattg gtccttctgg
    23881 gaatattcct ttttgttagc cttgtgttgg aatttaattg gcaatatggc ttagcttttg
    23941 tagtggcgat cagctatgct atgctttgga atgtccttca tatccaattc ttacgaaaat
    24001 actattttaa aaacgcatga gagtttcatg cgttttcttt tctaaatact ttgtcctgct
    24061 tttaattttt tcataaagat gatggaactt ggaatcagga cgatgatgct tccgatccag
    24121 gcggcggggt tagcggcggc ggttccataa aaaccgaaat actgcatgcc gatgatggcg
    24181 actgctgctc ggaaaatcaa ttctccaaag cctgctagtg ttgggataaa gcccttgcca
    24241 agtccctgaa taaagctacg aagaataaag agggaagcaa caatccagta acaagagccg
    24301 ttaatgatgt agtaaacaag agccaagtcc agcactgttt ggctggcatt tggcagaaag
    24361 agaccagaga agaagcgatt gcccaagatg agaatgaccg caaatacaat ggcccaagca
    24421 atgctgagga gtaatgagtg gcgcactcct tctcgaatac ggtcatagag cttggcaccg
    24481 tagttctgag cagtaaaggt tgcgatagcc aagtccagat tgaccatggg cagcatagcc
    24541 aactggtcag tacgaagggc aatggcctgg gcggcgatgg cgtctgttcc tagttggttg
    24601 accataaact gcaaggtcat ggctccgatg gcgataatac tggcttgaaa tcccattgga
    24661 aaagcaagct gggcatgttt cttgagatta cctctatcca attttaaatc agctagtccg
    24721 atatgatagt gaggtacctt gtggataatg taaaaaataa gaaagaggac cgaacaggct
    24781 tgagcaagga tagttgcaaa gccagctccg aaaacgcccc agttcataac taagataaag
    24841 aaaaaatcca gaccgatatt gataaaacaa gcgataacta gagccagtag aggtgtttta
    24901 gagtttccga gactgcgtag ggctgaagaa agaaaattat agaaaatagt aaaggtcaat
    24961 cctccaaaca tggccgttag aaaggcatgg gagtggtcga tgatactcac aggcgtttgc
    25021 attaagacca agataggttt caaaaaagct aaggctgaga ctgttagtaa aaggctgatg
    25081 agggaagcgt agaagagtcc gtggacaaaa gattttttaa gcccctctaa gtcgccagct
    25141 ccaaagcgtt gggcagaaat aatggttaat ccattggtaa caccttgggc aaaaccgatg
    25201 attaaaaaaa tcaggctggc tgtcgaaccg acacttgcaa aggaatcctt tcccaaagta
    25261 tgccccacaa tcatggaatc agcaaaatta taggccagtt gaaaaaaaga gccaatcaat
    25321 aagggaatag cgaattgtaa gatgactgca atcggctttc ctttggttaa atcattcata
    25381 atctctcctt ttgacagatg ataagcccac tagataaatg atagtctagt aggctttcta
    25441 gggataaaat atttctcctg aaaacggagt atagggcgta aatttgttat ttatactctt
    25501 cgaaaatcaa aatcagacgt tgttgacttg atttgatgag tgaaaggctc cagtggagcc
    25561 tttcagcctg ttaccttgaa acaaaatagt aacagggttc tatctgcgta agtagtaacg
    25621 aactacgttc gccctatctc caacctccaa aggttcccca aacctttgga gctagtctgt
    25681 ttttgatttt cattgagtat taatttgtca gttcttcaaa atgatcgaca gtgttatggt
    25741 ctgttactgc taagatgagt tcgtcagatt tgaagacata gtcaggagtc agttggatgt
    25801 ttaattcctg attttcgcca cttcggtaac cgatgatatt gagtttataa tgttggcgga
    25861 gttttaattc gccgagtgtt tttccaatcc attttactgg cgggtgaaac tcgacaatgg
    25921 aaacattgcc ttcgagctca aagaggctgg ttgtatcgcg gtggagtagt tgttttgcta
    25981 gagaaatacc tgtttcacgt tcaggagaaa taaccttatc ggcaccgaca cgaagaagga
    26041 cttctttcgc agttgttcct ttgactttga caatgaccat aggaacacct agaactttgc
    26101 tatgcatgac agccagaaca ctggattcca agttttcgcc agtagctaca acaacagcat
    26161 cgcagttacc gattcctgct gcacgtagga gcgagcgatc ggtgatgtct ccgacaatac
    26221 cgcgtgtgag aataggttct agatgattga tacgttgctc atgattatcg atagcaatga
    26281 tattgcaatc gtaattgtgt aatgtttttg caatggtagt accaaaaact cccaggccga
    26341 gaattccgat agtatagttt ggcatgattt ctccttttaa acaagcatag atgattttgc
    26401 gtattgaaga ctttcggttt tagataattt tcgaacagaa aggcttgcga gaatagaaag
    26461 tggaccgata cggccgaaga acatgagcgc cataatgact gcttgaccgg ccatggttag
    26521 gcttggagtc agatttgccg taacacctac agtggctaat gctgacatga cctcgaacat
    26581 taaaaataga agtggttgtc ggtcatctgt tagggcaagt gcgaagagcc ctatgataaa
    26641 cataagtagg aagactgaga atgtcgcaaa agctttgcgg atgctgaggt tatcgatggt
    26701 tcgtcccata aagttggtat gagggagacc gagaatctcg ctacgagcat agagcactaa
    26761 ggttaggaag gcggttattt taataccgcc ggctgttcca cctggggctc cgccaagcat
    26821 catctgaaag atatagagca agagggtgat tggttcagcc ttcgtatagt cgatgctggc
    26881 aaaaccagcg gttctcatgg tgaccgtctg gaaaaagctg gctaataatt tatggccaaa
    26941 tgatagttgt ccgatagtag aagggttgtt ccattcggtg agtaaggtag tcagagttcc
    27001 gagggtcagt ataatggctg tcaggcctag aacaatcttt gtatggaacc ctagttttcg
    27061 taggctacgt ttttgcccga tttgtgtctg aaggtcaaac caaaccgaga atccaagacc
    27121 tcccataata atgagactgg ctaatgttat gttgattaga ggattatcca catagcgcat
    27181 gatgctagtt gcgccaaaat tatcaaaacc agcattacaa aaggctgata tagctacgaa
    27241 aatcgaggta aataaacctc tcgcccatcc aaattcaggt acaaaatgaa aggacagtaa
    27301 gagggctcca aaggcttcga ccgccaaggt aaaaccaaaa gctgatttga ggaagttacg
    27361 aaaatatttt gtgtcagatc ggtttagagc ctcttgtaag gtcgccatat tgatgaaatt
    27421 cattttacga ccaccgcgta gagcgaagag accaataaat cctatcaagc tcaaaccacc
    27481 aatttggatt aacatcatac agataatctg tccaaaagta gaataggttt cagcaacggc
    27541 tttggtaaat agccctgtca cacaaaccat ggagacagat gtgaagagat gatcccaata
    27601 acttgctgta gaggtgctaa tttgtgagat gggaagactt agtaaaattg atccagtcag
    27661 aatcacgaat aagaaactga taatgattcg ctgactggga gaaagtttga tcctaaatgg
    27721 tgacataatt ctaccttttc tcaaaaaaat aaaagatgaa gatattgtag cacaaaagaa
    27781 agaaaatgta cgactaaaac acgcaaagaa cctgattttt ttctcttctt gaaagcttca
    27841 ttatttttta ttaccatgga ttttataagt ggtgtttata tgaggtggct cattatattt
    27901 gtgacaccag gattatgggg gaattattat ggacaatgaa aaagtggtgc ggaccataaa
    27961 aagaatctcc ttagttgacc tagggagatt tatttccatt ctgctaagac ttgttgatga
    28021 tagtgacgta aaggtccgac cttttggagg aggtaggtag cagccagtcc gaccaataag
    28081 cctgataaaa ttcctgtaaa agcgaggatt ggcaggtagt tcagtacata gaaagaacgg
    28141 gcgatggtag caaaaacaag aagctgacca agattgtgca acatcccgcc caaaatagaa
    28201 attccaatag gactgacacg gtttggaccg agctgcttgg cagagagcat tcctacataa
    28261 ctcaaagtag ttccggcaaa gccatagagg aaggttgaaa aggtgcctcc cagaaaggtt
    28321 gagatgagca agcgtagtgc gacaaccttt aggctatcct ttgtagggag ggtaaaaata
    28381 gcaattaagc taatcaaatt tcccagtcct agcttggcgc ctggagcaaa agcaaatggg
    28441 ggggtgatga gtcgttcaat caaagaaatg acaactgcct gagctgctag catcgtaata
    28501 aagttaagtg tttgacgttt agaattcatg ggtgtagaga aaaaactctt tctagtcgat
    28561 tatctatttt actatcatac ttgtttttgt tcactatggc aagttttgtt tgtgtatatt
    28621 actaattatt gaaatttgct tgtcaactat cttggaatac gatataatgg aaacatgtaa
    28681 tttgttttga ttttcacaag gaggaaacat tgtgacgaaa aatattgtga ttgtcggtgc
    28741 tggttatgcg gggattgcag cagctcgatt gctaggaaaa acttttaaaa aggatcaaga
    28801 tgtaacagtt accttgattg ataagaactc tttccatacc tatatgacag agttgcatga
    28861 agttgcggct gggcgtgtag aagccaatgc aatcaagtat gaccttcaac gtatcttcaa
    28921 aaaatatcca aaggttcaat tggtaacaga caaggttgtt gagattgact acgataagaa
    28981 acaagtagtt gcggaacacc aaactctgga ttttgattac ctgctccttg caatgggtgg
    29041 tgaggctaat gactttggtg tgaaaggtgt taaagaacac ggttttacac tttggtctat
    29101 cgaagcagca gaacgtttgc atgaccacat gattgacgct tgctatcgtg ccatgcgtga
    29161 gcatgatgaa gccaaacgtc gcgctctttt aacctttact gttatcggtg ctggcttcac
    29221 aggtattgag atgattggtg agttgattga ctgggtacca attttggcgc gtgagttcaa
    29281 gttggattca aaagaattct cacttaaggt tgttgaggca acgccaaata tcttggctat
    29341 ggttactgaa aaagagcaag tcaaggctcg caaatacctt gagaaaaaag gtgttgaatt
    29401 ggttcttggc gatggtgtag caagtgtaca agaagatagc ttgacacttt catcaggtcg
    29461 tcaaattcct acctatacct ctatttggac agctggtgtt caagccaata cagacgcaag
    29521 tgaatttggt attgaaaaag cacgtgcagg tcgtttgata gccaatgagt tcatggaagc
    29581 gaaaggcaag gaaaatgtct atgtagctgg cgacttggtt tactttgaag aatcagaagg
    29641 aaaaccaact ccacagattg tacaagcagc tgaacagaca ggccatactg cggcaagtaa
    29701 tattattgca gcaatcaagg gcggcgaaaa acatagctac aaaggtaaat atgatgggtt
    29761 tatggtatct attggagcac gctacggtgt agccttcttg atggacaaat accacatgtc
    29821 aggctttatg gcaatggctg tcaaacacat ggtaaaccta ctctacttct ttactatccg
    29881 tagtttcttc tacatgggtt cttatgttcg tcatgaattc tttgacattc agaataagcg
    29941 aaacattttt ggcggtcata cttcaggcaa aggaaatctt ctctggtctg tgccaatgcg
    30001 tgtcctttat ggttcagtat ggctctacga aggtatcaag aaagcctttg gtctatttgg
    30061 aacaacatca tggtttgggg atcaagttgt cttcccattc ccttggttag ctgatccagt
    30121 atctggagca tctgctgctg aggcggtttc aagtgcctca caagcggcaa ctgctgcggc
    30181 agaagtagct gaaccaattt ttggtttgag ctatgcttat ggtgaagcac cgatggctgt
    30241 tttggacaaa atgcctgatt ggtttgctac tatcatggaa tttatgatgc caaaccaaga
    30301 agtagcactc tttatgcaaa aatttatgac agtagcagaa atcggtatcg gtctggcttt
    30361 gattgctggt gcctttgtat ggattgtatc tgctgcaacc gttgctttgg tagttatgtt
    30421 cagcctgtca ggcatgttct actgggtaaa tatttggttc atcccagcag ctatttctct
    30481 tatgaatggt gcgggtagag ccttcggtct agactactgg attatgccat ggttgggtcg
    30541 tttcctagat aagaagattt atggaaagcc gaagcatatt taccgtatca aggataaaaa
    30601 ataaaggaaa tatagaaagt tagtggtaca tcaaatttgg aatacctatc ctgagattga
    30661 gaggggactt gaagaggtaa aatccatcat cttatctgag atgatggtcc tgcatccagc
    30721 agttacagcg aagattgttg aatatgtaga ggcgccaggg aaatacctgc gtgccggcct
    30781 ctgtctgctc tttgcacaaa tgacggaagg aaagattagc cgttcaaagc tatattttgc
    30841 tgcccattta gaagtcctgc atctggcgac tcttattcat gacgatgtga ttgatggcgc
    30901 ggataaacgg cggggagtca cggcggctca tcaacaattt tcgaatcgaa tcgctatcta
    30961 cacgggtgat tatcttctgg cctattcaag tcgactattt ggaaaggggc ttcgtttgct
    31021 agaggtgtca cgtgatgatt tggatttggg caatgataag ctgatggaaa caattcttcg
    31081 aggggaatta tctcagctac tcaatcaatt tgatgccaat atgactatga aagcctatct
    31141 caagcaaatt caaggaaaaa cagcttttct atttggactt gcctgtcagt tggggagttt
    31201 tgtaccaggc caatctagga aagacagtag catggctttt cggtctgggc aagcacttgg
    31261 catggccttt cagttacgag atgacttaat tgactaccag ctggatgtgg cagaatcagg
    31321 aaaacctaga ttgcaagata ttcaaaacgg tatctatact gcaccgctac tttttgccat
    31381 gcgagaagac aagtctatcc agcagcaatt gcgggcttat attcaatccc ctacggcaga
    31441 agggttggaa atccttacag ataggatttt tgcaacgcat gctattgcca aaacagagaa
    31501 actgattgtt agctatttgg aaaaaatgat gagttttgta gatagaatat cacagttatc
    31561 gactgcgtct atgcaaaatt tggtggcaat agtttttagt cattattttt aaaaaaatac
    31621 tagacaattt agtttattcg gtatatcatt ataagtataa aactatttac tttacaaaag
    31681 gagtattgtt atgaaaacaa ctaaagttgt gttgaaaagt ttggtagttc ttggtgcggt
    31741 atttgcactt gttgcttgtg gttctaaaca agaatctact tcaacttcat cttcaactac
    31801 agaaacagta gtattgaaag atggtactta caaagctgag tcaggcaaag acgattatgg
    31861 ctacaaaatt gttcacacat tgactgttaa agacggaaaa atcagtgagt caaaatttga
    31921 ctacgaagct gaagatggaa gtcttaaatc agcaaatgaa gagtacaaca aaaacatgaa
    31981 agataaagct ggagtttctg ctggtgaagc aatcgaacaa ctcaatgcag ctttggttga
    32041 gaaacaagac ctctcagctg ttgaagttgt atcaggtgca actcatactt ctgaagactt
    32101 caagaagagt acagaagccc ttcttgcagc agctgctgaa ggaaaaacag aaactgtaaa
    32161 acttgactaa ttaagtctat acagaaaaga cacagtcgca cttgtttggc tactgtgtct
    32221 tcttattttt gggggaaggt aaaatcagtg aaaaaaattg caagtctatt gttcgtgggc
    32281 ctactgatgg ttttgcttgt tgcctgtggt ggtaaacaaa acgaaagttt atctgttgtg
    32341 aaaactccgt tgactcgtag tgaaagctta cttcacacag tagtgcagtt gagtatttat
    32401 catgaaaatc aggaagaagc gatggatgaa gctgtctcct atatcaagga gatggaaagt
    32461 ctgttgtcca caaacttgga aggggcagat gtctaccgta tcaatcaggc agcaggaaaa
    32521 gaagctgtca aggttgatga acgtaccttt gaagtgattg aaacagctat tgacatgagt
    32581 aaagaaagtc aggggctatt tgacatttcc attggagctg tgagcaatct gtggaaaatt
    32641 ggagatgagg atgcacgtaa gccgagtgat gaagaaatca aagctgctct gccatttatc
    32701 aattataaag acattacttt agataaggag aagaagactg tctttatcaa agaaggaatg
    32761 accttagaat taggagccat ttccaaaggt tatattgcag ataaggttag agaattgttc
    32821 gcaagcaaag ggattacgac agccatcatt aatctaggtg ggaatgtagt ggttatgggg
    32881 gattcgccaa cgacacaaaa tggttggaat gtgggagttc aagacccaga ccaagtgcgt
    32941 ggatcaacgg tcggttctgt gccagggaca catgattcgg ttgttacctc aggtatttat
    33001 gagcgctact tagaggtgga cggtgtcaaa tatcaccata tccttgatcc caaaactggc
    33061 tatcctgtgg aaaacgatat ctcaggtgtg acagtctttt ccaaaacatc tatccaagga
    33121 gatgccttct ccacaactct cttcttacta ggtgtggaaa aaggtcttga ctttatcaat
    33181 cagattgacg gtgtagaagc tgtttttatc gataaggagc agggcgttca tctgagtgat
    33241 ggcttgaaag aaagctttga attaacgaat gaggagtatc atcttgttaa tgaataaatc
    33301 aactaaaggg ctcagtttgt ctgtatttct agaatttgtt gaaatgaaga ccaaggtagc
    33361 tagtgttttt ccgatgaccc tggggatttt atggagcctg tatcgctatc aagctttcaa
    33421 ttggctcaat actctcctct tcattattgc cgtccttagc tttgacatgt gtacaactgc
    33481 catcaacaat agcatggact accacaaggc caaggatgaa gcctatcgtc aggaaagcaa
    33541 tgtgattgga aaattctccc tagattttcg tcagatgatt ggaatcgtcc ttgctctact
    33601 tattttttct ctactggttt cattactcct tgtatggcgg accagttggc tcctcctacc
    33661 gatgggagct ctctgtttcc tcattggtat cttctatacc tttggaccta ttccgctttc
    33721 gagaatgcca ctgggtgaag ttttctctgg agtaaccatg ggatttggca tcttctttct
    33781 tgctgtattt attcagcaac cagatttgct actgaccagc caagtgagcg gtcagtggat
    33841 gactttgcaa ttttcttgga taaaaataat tgaaattatt ttcatgtcca ttcctctggt
    33901 aaccttgatt gctaatatca tgttggctaa caacacctgt gatttagaag aagatattcg
    33961 caaccatcgt tatactctgg tttactatat tggcaagaaa aatgctctta aattgtattt
    34021 tgtcttggca agtttaccat ggttgctgtg gataatctac tgtctgatag gattcttacc
    34081 aatttgggca ttggccggtt taatcggagt ttggcctgct tataagagtc tagaaacatt
    34141 tttgaaaaag caactcaaac gggaaacctt tatcgaggca gtaaagagtt ttgtactctt
    34201 tgcgctgcta tatgtggtga tacttgcttt agcccttatt ttctaaaaag gaaagacaca
    34261 gtcgttcatc aggctgtgtc ttctttgtta tatcgtcatt tagtttttct tttattactt
    34321 cgacgagcga ggaaacatcg tttcctaatt tccaacttca aacactccac tggagtattt
    34381 gaactcgcct tgtctgattg aaacagtctg ggggactgtt tcaagtcaat gcctagaaat
    34441 aagaaagcat tgagttatgc ctgcggcttt tgatgcgaac tttgttcgct ttatctccaa
    34501 cctccaaaga tttcccaaac ctttggagct agtactaaaa gtaaactaaa agactatagt
    34561 ggtaaaataa gttcttcttc gtcagtgttt tccccgccaa cggatttgat ttcaatcaac
    34621 aggttatgtg gcaggcagac ggagagttga cctggctggc taatccagct ggtcataacg
    34681 gcgatttggt ctgggctatt gtcttccttg acacgaatgc gttcgccatc aacttcaatg
    34741 atattgtatt gcccttcatt gggatagtag gtcttttctt gacggggtgt gtcctttgat
    34801 aattcaaatt ggtcgaccac ctcaccattg atgcggacat aggcaattgt ttttgcctca
    34861 tttgcatctg ttgtcagttg tgtgtaggta aaaattgctg gaagaaagga taaaactagg
    34921 gtgaatccga ttaagatata atcaaatagt ttgagttgtt tgagaatgga tttgaatgtc
    34981 atatacaatc tattttatag aaaaaatcct actttgtaaa atgttggata cagactactt
    35041 tttcaattgt ccaataaaga gcaggagagc aaatattccc caaaatccag ctaggagtgg
    35101 tttgatttga ccagtgaaaa atccaatgga gaaggttagg acaagacctg caaagagaaa
    35161 acatagcagt ggtttacgat aaagatggat agcttcttgg acagcatttg attctggact
    35221 ggtagtttgc cagtcactat tcaagattgg aagtatagtg aacggtaaga taaagattgg
    35281 tggattgtcc ccagtcaggt agctatgtat atacaggcta caaaatgttg tataggagag
    35341 aacaatcaaa gtgagtataa gtttcggttt gttaacgttc atctgttttc tcctttttga
    35401 aatacaatcg ataaagaata gccagagcaa atccagcagg aaggatgagg atatgtggtt
    35461 tgacatgtcc tagccaaatg cccacggaat aggtcaaggt catggcaaac agggcaaaga
    35521 tggcttgaat gataaagtat cgtttttctt cttctgtttt aaaggatctg ataatctgaa
    35581 tgggcggtaa catgagcaag aatgaaccgc taatcggctc attgaccatg taagagtaga
    35641 tgaagaatgc agaaaataaa gcataaaata gaacaaaaaa tcgacaggtt tgtttgggtg
    35701 taaaaggttt attcattagg tctgctcctt attttttctt ggcagtatct gcttccagtt
    35761 tttgcagata ggcaagggca gacagggcta gactggcaaa gaggcccatc ataccaccga
    35821 agaggaggga tttgacgtgg aagctggagg ccagtagggg aagctggagg ctaaagaggt
    35881 ctgacagccc agcaaagagg ctagatagca gggcaacacc cagtccccaa acgagtggat
    35941 tgagggtctg tccttgtctt tcctcaggac ttagttcctc catgtcatat tgaggcaggt
    36001 cagcatggag ggtgcgcata ttaacgatac caattaggat aatactgaag aaggcaatta
    36061 tcattggata gtaggcagcc acctccacag gatagcggta ggctaggaag taggcgatgg
    36121 catttccaag agctaggaag tagaagtagt agataaaggc ctgtccgccg atagcatcag
    36181 cctcggcctg tcggtattcg tctaaaggac cgcggatacc ataaaaacgt ttaatcatat
    36241 ttttgatcca cttgggttct tcttttgaaa tagcagagct gatagttagg ttttctgcct
    36301 ttttcatgcg cttgcgtaac atgatttcaa gagcaatgcc cgtgaaaata ccacctagac
    36361 aggctgcaag gaattttcgg aggtcaaata ggtggtcgaa agggttgagc ccctccatcc
    36421 aggcaccaaa aacaacagtc caaatgtaca taacggcagt gaaatagagg gcgaatttga
    36481 tacttgctcc cttgagctgc ttctgttcct tggtagtcag ttcctctaca tctaaactgt
    36541 ccacttggct gtggcgcatc ttggatgtca tatacatact ggaggaaaga gtggatagga
    36601 gtagagcagt tgggtagcca taggcaacga cttctgggta gcgtttggat agagcgagtg
    36661 ccagtagggt aagagccatg gtgccccaaa agagcaggat aaagcaggta ttgcctagtc
    36721 gggaggcttc tttttggcga aattcatcca agggtcctgc gataccgtaa aatcgtttga
    36781 ttaatttatc ttgaaaggtt tcttttttca taagcagctc cttatttttg aacgaacaat
    36841 ggtaagatgt aaacaaagcc taagaagtag atggtcccag caatcagcaa ttgtagccaa
    36901 aattttgctt ggctgatggt gtgcaagatt tctgctccgc tattgcccca aagctgaaag
    36961 aggacaaaga gcgggataaa aataagggta gagataagag cttgacgtat attctttttc
    37021 atggtttttc ttccttttat ttgtttgcga gaattttctt ttgtaactgc ttcttacaat
    37081 agtagtaatg gatgaaggtg atagctcctg caacaattaa ccgacctagt aggagggtcg
    37141 ggtctgttag ttcttcaaga aatacagacc attctttata gaaagcaggg gcagtcgtgg
    37201 aagccaggaa ggctccgaaa aatgtgctac gactactttt tacaagagat ttattgagct
    37261 tggtcacatt aatttcatcc tcatagcttt gactaatgcc atttttcaag gcaaggtggg
    37321 aagctaaggc ttgcgtgaaa ccgatgatta gtatattggt tagggggagc agaaagccaa
    37381 ctttttcagg ttgtcgtagg gcaataagaa gtgcaatcgt atttcctatt agcaggatag
    37441 gaaaaacaat catgacaatg gtgttactga ggcgatagct ttcttgcaga cgcatttcat
    37501 ccatgggacc actaatggaa taaaaatcct tggttgcttg attgagaatt tttgtaaaaa
    37561 tatctttcat gatgaactcc ttattgattc caaaagagac tattaaggtc agtctgtaaa
    37621 gctttggcta ggttgataca gaggtctagc gaggggttgt acttgttgtt ttcaatcata
    37681 ttgatggtct gcctggatac gccgatagcc ttggccagat ccagctggga aatcccaagc
    37741 aataggcgat aatctttgac acggttcatg tgccctcctt tctatgtcaa ttatatctga
    37801 catacttggc taaaaatgag aggataggtt gactatcctt ttaaattgtt gtcaattata
    37861 tccgacatac aagtgtaaaa aaatgtggga gacctccctg ttgatgtcaa ctatatgtga
    37921 catgtttctt tactgttagt atatacctgt tcatataagt tgtcaactat atttgacagt
    37981 ttttttgtaa aaagtttgca acaacttttt attttaattt gtggtacaat ggaaaagata
    38041 tgaccaagga atttaatcac acaactgttc tcttgcatga gacagtcgat atgttagaca
    38101 tcaaacccaa tggaatttat gtagatgcaa cgctgggtgg agcgggtcat agtgagtacc
    38161 tgctcagtca gttgacggat ggtgggcatc tttatgcctt tgatcaggat cagactgcta
    38221 ttgatcatgc ccatattcgc ttggcatcct acattgaaaa gggacaagtg acctttatca
    38281 gggataattt ccgtaatctc aagactcgct tggcggagct aggtgtaaca gagattgatg
    38341 ggatttgtta tgatttagga gtatctagtc cacagttgga tgagcgggag cgtggctttt
    38401 cttacaaaca agatgctccg cttgatatgc ggatgaatcg tgagggacat ttgacggctt
    38461 atgatgtggt caataactat gattatcacg acttggtacg gattttcttt aaatacggtg
    38521 aggataaatt ttccaagcag attgctcgta agattgaaca ggcgcgtgcg gtcaagccga
    38581 ttgaaacaac gactgagttg gcagagctga tcaaatctgc caagccagcc aaggaactta
    38641 agaagaaggg ccatcctgcc aagcagattt tccaagcgat tcggattgaa gtcaacgatg
    38701 agttgggggc agcagacgaa tctatccagc aggccattga cttattggct ttggatggac
    38761 ggatttctgt tattactttc cattctttag aagatcgttt gaccaaacaa ctcttcaaag
    38821 aagcaagtac gattgatgtt ccaaaaggtt tgccatttat tccagatgac ttgaaggcgc
    38881 cacttgaatt ggtcaatcgt aagcctatct tacctagtca agaagaatta gaggcaaata
    38941 atcgcgcgca ttcagccaaa ctgcgtgtag ctaagaaagt acataaatag gagagagtct
    39001 atgttgcaag aaaaacgtag agaagccact atgcgggtta tcggtgataa aattagaacc
    39061 ttcacacgtg tagaaaaagc cttctattca agcatcgtat tatctggatt agcccttgcg
    39121 ataggaatta tctttatgca aacgcggctt ttgcaacttc aatctagcat ggccaaagtc
    39181 aatcaagaca ttagccaaaa acagattgaa attaacgatg ctaagcaagc tgtcaatgaa
    39241 ttgacacgtt cagctcgctt gatggaaatt gctgaaaaag ctggattaac ttttaataat
    39301 gacaatattg gagtagccga ataatgccca gaagaaataa taaactcttg cggtatgtct
    39361 tgaaaaaacg atatgttccg tcaaaaaatc gtcgaagagt aggacagagc ctacttcttt
    39421 tgacggtttt cgtctttttt ctctttttaa tcaactttgc ctatattatc ggcaccgata
    39481 gtaaatttgg ggtggacttg tcagagagag ctgatgcggt acaccagcgt gaagttatcg
    39541 ttcaagctaa acgggggacg atatacgacc gtacaggaat tcctattgcg gaagattcaa
    39601 cgacctatac agtctatgcc atcattgaca cagaatatgt gtcagaactg aaaaaagttt
    39661 tgtatgtgca gtcttctcag ttcagcaaag tagcagaaat ctttaaaaag catctcggaa
    39721 tggagacaga ttatgttatg gagcagctga atcaacctga actgaagcag gtatactttg
    39781 ggaccttagg taagaatatc tcctatagta caatgtcgtc aatccaagaa gagatgaagg
    39841 cggcaggtat tgaagggatt gcctttaacg ctagtccagg acggatgtat ccgaatggaa
    39901 attttgcttc aatttttgtc gggttagcta atctggttga aaacaaggat ggtagtcata
    39961 gtttacaggg tgtgagtggt ttggaatatt atctgaatga tattctggct ggtcaagacg
    40021 gaaaggttat ctacgagaaa gatagtcaag gccgtgtcct acctgggaca gaaaaggttg
    40081 aaacggagac agtaaacggg caggatgtct atacgacaat ttcagccgat ctacaacgtt
    40141 ctcttgaaac caatatgaat accttttttg ataacgccaa agggcgatat gcgaatgcaa
    40201 ctttggtttc agccaagacg ggtgaaatac tggcgacgac ccaaaggcca agctatgatt
    40261 cagataccaa agaaggtctg ggacaagaag gactgctaga gcggtcactc ttatatcaag
    40321 aggcctttga gcctggttca acaatgaagg tgctaacagt agcgtcagct atcgataacg
    40381 gcacctttga cccaaatgca tattatacca ataatgagta cgttattgca gacgcgaaaa
    40441 tcaatgactg gaccctcaat gcaggttatt cagctgtgac tctcaattat gcgcaaggct
    40501 tctccctatc cagtaacgtt gggatgacct tattgcagca acagatggga gatgaaaaat
    40561 ggctaaatta cctcactaag ttccgttttg gctacccaac gcgttttggt atgggggacg
    40621 aggcgccagg aatggtacca gaggataaca ttgtttctat cgccatgtca tcgtttggtc
    40681 aggggatttc tgcaaaccaa gcacagatgc ttcgtagttt taccgccatt gcgaacaatg
    40741 gtattatgct agagcctaaa tttatctcag ctctttatga tcctaataca gatacagcta
    40801 gagtttcttc gaaagaagaa gtaggaaatc cagtttctga acaagctgcc gacgatacac
    40861 ttcgctatat gattaatgtc ggtactgacc ctgtttatgg tacgctctac tcacatgact
    40921 tacaggggcc tgcaattcag gttgacggct atgatattgc agtcaaatca ggtacggcgg
    40981 aaattgccag cgaagatggt caagggtata ttaaaggtgc ctacatcaac tctgtagtag
    41041 ccatgatccc tgctgaagac cctgaattta tcatgtatgt gaccattcgc caaccggaag
    41101 tattaaatgt cctgtcttgg cgtgacattg tcagtcctac attgaaagaa gcgatgctgt
    41161 tgaaagacaa tttgaatctg gattcacctg caccagcatt ggcacgggtc gctaatgaga
    41221 cagagtatca attgccagac ctcattggta aggcaccagg cgagtcggct gaggaacttc
    41281 gccgtcaatt agttcaacca gttatccttg gaaacggtgc tgaaattaaa aaagtttcag
    41341 tcgaaaaagg aagtaaggta atcgccaacc aacaggttct actcctgaca aataaattcg
    41401 aagaaatgcc agacttgtac gcaatcacca aagagaatat ggatatattt gctgaatgga
    41461 ctggtatcga agtgacctat aaaggaacgg gttcaaaagt agtcgaccaa agtgtagagg
    41521 tcggtaccgc tttgaataaa accaagaaaa taacaataac cttaggagac tgacatgcaa
    41581 ttcgcactta tgtcgggatt ggtagctttt ctagcaaccg ttctcttaat cccacgattt
    41641 attacatttt atcaagccaa acgcattgag gggcaacaga tgcacgaaga tgtgaaacaa
    41701 catcagttta aggcaggtac accaacaatg gggggaacag tttttctcgt tgttgcgatt
    41761 cttgtcagct tgttgtttgc aacggccttt caactgttga cgggtggtgt ccttgccatc
    41821 ctcttcatcc ttgcccttta tggtgtagta ggatttttgg atgacttttt aaaaattttc
    41881 cgtaaaataa atgaaggtct taatcctaaa caaaagcttg ctctacaaat tttaggaggt
    41941 attgtcttct actttgtcca cgtaagagga gcaggtggcg gagaattgaa tgtatttggt
    42001 cacatggtac atttgggagt tctctatttc ccatttgttc tgttctggct ggtcggtttt
    42061 tcaaatgcag ttaatttgac agatggcatt gatggattgg cttctatctc agttgttatc
    42121 agccttctag cttactctgt catcgccttc aatgagcaaa aatttgatat tcttctagtt
    42181 tgtgtgacca tgattggtgg cttgctcggt ttctttgttt ataaccgtaa accagcgaag
    42241 attttcatgg gggatgtggg aagcttggct ctcggcggta tgttggcaac tatttcaatt
    42301 gccctccgtc aggaatggac tctcctcctt atcggcctgg tctatgtcat tgaaacgtcc
    42361 tctgttatgt tgcaggtttc atattttaaa tacaccaaaa aacgctttgg agaaggtcgt
    42421 cgtatcttcc gtatgactcc ttttcatcac catttggagc ttggaggttt gaccggaaaa
    42481 gctgaaaaat ggagcgagtg gaaagttgac tttttcctct ggtcagtcgg tctcatcatg
    42541 agcttgatta ccctagctat tctttatcta taaaatgtca gaaacagcag aaatgctgtt
    42601 tttttacctt gacaaatatg gtcggggggg gggtaaaata gagagagaat tggtggagga
    42661 taaaaatgga acaattcaat caagaacagt tatatggagt ggttattcaa accatgacag
    42721 ctgctagtca acttcctatg gttaaagtca atcgggaaga atttttgaag actcgtttta
    42781 aagatagtcc ctatctagat aaaattattg cggatggacc aacggcggtc ttcactacaa
    42841 aagctttgcg taaggaagct gaaaaaatca ttaatgatat gactacgaaa acatctttga
    42901 tttctttcgc agctggttta ccggggaatc catttacagc ggtggcggca ggtactgctg
    42961 atatagctca gtattttggt tttgccttga atttgtcgca acaaatcgct tatctttttg
    43021 gtgaagatga attatttgtt ggtgaaggga aggaaatttc agaagaggtt caaatccgca
    43081 ttattgccta cattggtgtc atgtttggag caggtggttc agcagttctt ctcaataaag
    43141 tatccaagac agtcggagct aatatcggta aaaaagtagc tatgcaggct ttgaccaaga
    43201 caacttggta tcccttggtg aaaaaggtag ccgcagtgat tggtgtgaaa attaccaaaa
    43261 agactgttga aaagaccatt gccaatgcag ttcctatttt gggtggtctg atttcaggag
    43321 gtttgaccta ttttaccttc cagcccatgg gagggatgtt ggcagacaca tttgtgaaaa
    43381 aaataaatgg tgattttgat ggcgaattag aactcactga ggcctttaaa gcaagtttgg
    43441 aagaagagaa ggaacttgga attattgagg cagaatttac tgaagcaagt gagagttgat
    43501 taggacgggt atccgtcctt tttgcttgtc cacctaaatc gtgctataat agagggaata
    43561 caactaaaga ggaaactatg aaatttacag atatgaaact caagccttat attcaggagg
    43621 ctttgaaaga aattaacttt gtccagccga cagaagttca ggagaaattg attcctgttg
    43681 ttttgtcagg gcgagacttg ataggggaat caaaaacagg ttcaggtaag acccatacct
    43741 tcttgatccc gatttttcaa aaattaaatg aggaattgga ccaagttcag gctgttatta
    43801 cagccccatc tcgtgaactg gctactcaga tttatcaagc ggcacgccag ttggctagtc
    43861 attcggacac agaagttcgt gtgaccaatt atgttggcgg tacggataag aaccgtcaaa
    43921 ttgacaagct tcaagctagt cagcctcaca ttgttgttgg gacaccaggg cgtatctatg
    43981 atttggtcaa atcaggtgac cttgctatcc ataaagccaa aacctttgtg gttgatgagg
    44041 cagatatgac cttggacatg ggctttttgg aaacagttga taagattgct ggcagcctgc
    44101 caaaagactt gcaatttatg gtcttttcag cgaccattcc gcagaaactc caaccgtttt
    44161 tgaaaaaata cttgtccaat ccagtcatgg aacaaatcaa gacccatacg gtcatttcgg
    44221 ataccattga aaactggctg atttcaacca aggggcgtga ccgtaatgct caaatcttgg
    44281 aagtaaccaa gctcatgcaa ccttacttgg ccatgatttt tgtcaataca aagacacgtg
    44341 cagatgaatt gcatagctat ttgactgcga acggtcttcg tgtcgcaaag attcatgggg
    44401 atattcctcc acgtgagcgc aagcggatga tgaaccaggt gaagaacttg gactatcagt
    44461 acattgttgc aacggattta gcagcacgtg ggattgatat tgagggcgtc agtcatgtca
    44521 tcaatgatgc cattccacag gatctttcct tctttgttca ccgtgtgggg cgcacaggtc
    44581 gtaatggttt atcaggcatt gccattaccc tttatcagcc aagcgatgat gcagatattc
    44641 gagagctaga aaaactcaat atcaaattct tgccaaaaga aatgaaaaat ggcgaatttg
    44701 tcgataccta cgaccgtgac cgccgtgcta accgtgaaaa atctcgtgaa aaactagatt
    44761 tggaaatgat tggcttggtc aagaagaaaa agaaaaaagt caaaccaggc tacaagaaga
    44821 aaattcaatg ggctgttgat gaaaaacgtc gcaagaccaa gcgagttgaa gcgcgtgcaa
    44881 agggtcgtgc agaacgtaaa gccaagcgtc aaacctttta aagtaatcga ggaaaaagat
    44941 gttacaaaac attctaagtt tttatttaca aggattgcta atagcttcct tgttgattat
    45001 cacttctagt ctggtctggt ttatctggcg tgcgacaaag ggtgtggata aaaccttgca
    45061 agaacgacaa gatttcttgt ttgatttgtt gatgattaat gtgatgacaa ttcccattgc
    45121 agcctttgga gtagtgggaa tcttattaat gtttaaagcg tagaaggaaa aagtatatgt
    45181 acgatacagt tgtaattggt gcgggtcctg cggggatgac tgcagctctt tatgcagggc
    45241 gtagcaattt aaaggtagct cttttggaac gtggtattta tggtggtcag atgaacaata
    45301 ccgcggaaat tgaaaactat ccaggctatg accatatttc aggtccagcc ttggctgaaa
    45361 aaatgtttga acccttggaa aaattcggtg tggaccatat ttttggcacc ctagtccgta
    45421 ttgaggaaga aggacaaatt aagaaagtga ttactgagga tggtgttttg gagacaaaga
    45481 cagtcgttct agccatgggg gcaaaacacc gtttgttagg tattccaggt gaggatactt
    45541 acaatagccg tggtgtctca tattgtgcag tctgtgacgg tgccttcttc cgtggacaaa
    45601 aactcttggt tgtcggtggt ggagattctg cggtcgaaga agctctcttc ttaacacagt
    45661 ttgcggagtc tgtgacaatt gttcaccgcc gtgatcagct tcgtgctcaa aaagtcatcc
    45721 aagaccgtgc ttttgccaat gaaaaaatta acttcatctg ggatagcgta gtcgaagaaa
    45781 tcaagggcga tgacttacgt gtacaaagcg tggttatcaa aaatgtgaaa acagaggaag
    45841 tcagcgaact ggacttcggt ggtgtcttta tctatgtcgg tctggatccg atgactgata
    45901 cagttgcgga cctaggaatt acagacgaag ctggttgggt tatcactaat gaaaagatgg
    45961 aaacgaccca atcaggcatt tatgccatcg gtgatattcg tcaaaatcaa cttcgtcaga
    46021 ttgcaacggc agtaggaaat ggtgcagttg ctggacaaga agtctataac tacatcacag
    46081 aactagctga ataggggaat acaatgtttc atatttacga tattcagaaa aatctagatg
    46141 gcatcttctt tgataaaacc ttggatttac aggaagaatt gcaagctcga aatggtgaag
    46201 ttctaggctt gtcgccagtc caagtcactg gaaatgtccg ttttgaatca ggcttctttt
    46261 tcttggacta tcagatgact tatgatatta ccttggcatc cagtcgttct ctgcaaccag
    46321 ttgttttgca tgaggtccaa aacgtcaatg aactctttgt tgccaatgaa gcagttctta
    46381 aagaacaaga tttgattgat gaggatatgg tactggtagt agaagatgac cacattgtcc
    46441 ttgatgagag tgtagcagat aatattttac tggctatacc aatcaaagtc ttgacacctg
    46501 aagaagaagc tggacaggaa ctaccatctg gtaaagcttg ggctttaatg actgaagaag
    46561 attttcaaca aaaagctcaa gagaaaaaag aagccaatag tccttttgcc caattacaag
    46621 ggttatttgg agatgaggac taactcagat tggcaagata gttaaattat ctgaaaattc
    46681 ttgtcaattt taagctttca gtgtataata aaagagatac aaattagagg agtaaacaaa
    46741 tgactaaagc aaattttggt gttgtaggga tggccgttat gggccgcaac cttgcgctta
    46801 acgttgaatc acgtggctat tcagtagcta tttacaaccg ctctgctgat aaaacagaag
    46861 atgttgttgc aagcaaccca ggtaaaaact tggtaccaag ttacgatgtg gaaagctttg
    46921 tggcatctat cgaaaaacca cgtcgcatca tgcttatggt tcaagctggt cctggtacag
    46981 atgcaaccat tcaagcgctc ttgccgcact tggatgaagg tgacatcttg atcgatggtg
    47041 gtaatacttt ctacgaagac actatccgtc gttcaaaaga attggcaaac tcaggtatta
    47101 acttcatcgg tacaggtgta tctggtggtg aaaaaggagc ccttgaaggt ccatctatca
    47161 tgcctggtgg tcaaaaagaa gcttacgaat tggtggcaga tgtcttggaa gaaatttcag
    47221 caaaagcacc agaagatgga gcaccatgtg tgacttatat cggtccagat ggagctggtc
    47281 actacgtaaa aatggtacac aacggtatcg agtatggtga catgcaattg attgcggagt
    47341 catatgattt gatgcagcac ttgcttggct tgtcagtgga tgaaatggct gacatcttca
    47401 ctgactggaa ccaaggcgaa ttggatagtt acttgattga aatcacagcg gacatcttga
    47461 aacgcaagga tgaccaaggt caagatggac caattgttaa ctacatcatg gacgctgctg
    47521 gtaacaaggg tactggtaaa tggactagcc aatcgtcact tgacttgggt gtgccattgt
    47581 cattgattac agaatccgtc tttgctcgtt atatctcaac ctacaaagat gagcgtgtgg
    47641 cagcaagcaa ggtccttcca aaaccagctc cgtttgcata cgaaggcgac aaggctgaat
    47701 tggtagaaaa aatccgtcaa gcattgtact tctcaaaaat catgtcttat gcacaaggtt
    47761 ttgcacagtt gcgcgtagca tcaaaagaaa acaactggaa cttgccattt ggtgaaatcg
    47821 caaaaatctg gcgtgcaggt tgtatcatcc gcgctcgctt cttgcaaaag attacggatg
    47881 cctacggacg tgatgaagac ttggcaaact tgctcttgga tgagtacttc cttgatgtaa
    47941 cagctaagta tcaacaggca gttcgcgatg ttgttgcctt ggcagttcaa gcaggagttc
    48001 ctgtaccaac attctcagca gctattacct acttcgatag ctaccgtgct gaaaacttgc
    48061 cagcgaactt gattcaagca caacgtgact actttggtgc tcacacttat aaccgtaaag
    48121 ataaagaagg aatcttccat tacgactggt atagcgaatc aaaatagaaa agatgggcgt
    48181 ggaagcgccc ttctttctag tcataatacg attcctacac catttgaaag aatagaaaag
    48241 gatggacaat ggctaagaaa attttgattg ctggtaaaga acgcaatctc tcgcattttg
    48301 tttccatgga attgcaaaaa aaagactatc ttgttgatta tgcatcgaca gggaaagagg
    48361 ctatgtcctt ggcacatgaa acggattttg acttgattct gatgagtttt cagctttcag
    48421 acatgtccag caaggaattg gctacagaac tgttagcgat aaaaccagcc acggtcatga
    48481 ttgtggtagt tgagccgaca gaagttagtc aatatgggga agaagtcctc tcttatgctg
    48541 tttcctacgt ggtgaagccc tttgtcatta gtgatttagt ggagcaaatc tctgcgattt
    48601 ttcgtggtcg tgactttatt gacaataact gtaaacaggt tcacatgcat gcggcctatc
    48661 gtgatttgaa ggttgatttt caaaatcgaa cagtgactcg aggtgatgaa ttgattaatt
    48721 tgacccgccg agagtatgat ctgctggcaa ccttaatgaa tagcccagag cctgttagtc
    48781 gagaacaact tcttgagcgt gtttggaaat atgaagcggc ttctgagacc aatgtcgtcg
    48841 atgtatatat tcgctatcta cgtggtaaac tggatttgcc acatcaagat tcatatataa
    48901 aaacagttcg tggtgtcgga tatgccatgc gcgattgatt tagagtagag aggagggaag
    48961 ctttccctct ttctttttct ataagcgtgt gataaaataa tagccaataa gtaagaatgg
    49021 aaaagttatg aatacatcat ttaaagaaaa agtcatattg atactcttat ctggagcgac
    49081 attattagct gttctcaact ggtctagtat ttatggggct attcaacaat tattgggcag
    49141 tatgaattcg ctttttattg gagctatttt tgcctttatt ctcaatgttc ccatgaaaaa
    49201 attagaagat cagtttgaaa aaatttcttt tttaaagaaa tccaagcggt ctttggcaat
    49261 tgttggagta ttaattggat ttgctttaat tgtgacagga ctggtagtga ttgttcttcc
    49321 tacattggtg acgactgttt cagaactggt ttcggttagc agcacagcca ttccaaaatc
    49381 ggtaaatgcc ctgactaatt ttcttgaatc aaatggtctt ttgtcgggac aaatcggaga
    49441 ccagattgcc agctttttgg atcagttgaa gaatttaaca cttatttcaa gtttggtcac
    49501 accgatttta tctggcttgg tgtccaatgt gacggggatt ttttcgaaca ctatgacgtt
    49561 gataatggct ttcttcttca ctctagcgat tttagggagc aaggaacact tgcaggcgat
    49621 gacgagaaag ttcttgcagg ctaccttgcc agagaaggct gtcagagtag tgaactatat
    49681 tggagaagtt attgttgata cctatgaccg attcttgatg agtcagattg ttgaggcatg
    49741 tatcattggg acacttgtct ttgttagtta ttcgctctca ggaattcctt atgccagcat
    49801 ggctggtatt ttggctgggg tcctatcatt tgtaccttat atcggtccct tttcagcgtg
    49861 tttgattagt gctctctttg tggcggtaca aaatccgctc ttggcactct ggtctatcgc
    49921 ccttttccag attattcagc tgatagaagg aaatgtgatt tacccgcgcg tggttggtca
    49981 atcagttggt cttccgaccc tctttaccct ggctgcagcc ctgattggtg gtaatttgtt
    50041 tggcctactt ggtatggtct tctttacccc aatttttgcg gttgtctatc gcttggttcg
    50101 tgaatgggtt gccagtcgat tgaagaagca agatgaatta ttggtagaaa gtgagtaatt
    50161 ctcgctttct tttatttttg tcatttttat gctatactga agtgataaag tttatgtagg
    50221 agaaagagta tgcgttgtcc aaaatgtcag agtttgaaat caagtgtcat tgatagtcgt
    50281 caggctgaag atggcaatac catccgtcgt cgtcgttcct gcgaccaatg tggtcaacgt
    50341 tttaccacct atgaacggat tgaagagaaa actctagtcg ttgtgaaaaa agacggaact
    50401 agagagcagt tttcacgtga aaagattttc aatgggatta ttcgttctgc tcaaaagcgc
    50461 cctgtgtcaa ccgatgatat tgatgaagtg gtgaatcgga ttgaacagaa ggttcgagca
    50521 caaggtgata gtgaaataga atccgatgtc attgggaatt tggtaatgga agaattggtc
    50581 gaattggatg aaatcactta tgtgcgtttt gcatcggttt atcgttcttt caaagatgtt
    50641 ggagagctag aaaatttgct taagcagatg atctccaaag gaagtaaggt aaaaccggga
    50701 aaaaaagatg aaaccaaatg atttatttgc ctatataaaa atcagcccgt ttacacctga
    50761 tattgtcagt cttagcaaat gctaccagcc gattatcggt tttgatgcat tagcgcttta
    50821 ttattacttt tatagttttg ccgatcaagg gcaaggacgt tacaaatgga ctgtcattct
    50881 caatcacatg gattttggga tgaatcgttt ggagaaggct ctggatgttc tgactgccat
    50941 ggggctccta gaactctatc gtgcagatga attaacaggt ttggcgctac aagcccctct
    51001 gaccgtaaaa agttttctag cgaaaccctt gtataagaac ttgttggcaa ggaagattgg
    51061 ggagtcaagt atggagaatc tgcttgttca ccaacccaat caagaacaaa atatttcaaa
    51121 aacattttct caggtcttta ccatggatgg gcaggctcca gttgtttttg aaccgaaaca
    51181 tgattttgac tggtctgcct tcaaggcatt aatggctaaa gataagcttc tttttcagga
    51241 tgaagctgag gatattattg cgcttagtta catagcagag caggcaggtt ggacctggtt
    51301 ggaaacctat cggcaggcta aagcaacagc tattggacag atgatctcga ccaaacgctt
    51361 gcagcagtca cgtcagtcat tgccaacaga aagcgccaac ctcactgccc aagaacaagc
    51421 cattgttcgt gaagcgaaat caaaatccag cctaaccttc ctgtccttta tcaaggagca
    51481 acggaaggca gcggtgacag gaacagaacg aaaatgcttg acggatttgg ccaatttggg
    51541 tctgcttgac gaagttatca atgtcttggt cctctatacc tttaacaagg tggactcagc
    51601 caatctaaat gaaaaatacg ctatgaagct gggcaatgat ttttcctaca agggaattgg
    51661 cagtgcagag gcagctgttc tttatctaag agagttaaag acaggtcaag ctgttaccaa
    51721 gtcgagccag ccacagaaaa gcaatgtgcc tgagtggagt aaggaagagg ttgtcatgga
    51781 taacagtcct gaagctcagg caagaatgga agcgcttagg aaacgaatgt tagaaaacga
    51841 aagtaaggga ggtagctgat gaaatcagtt caagacaggt tgtcgcaggc aaccaatcca
    51901 agttcaaaat cttatcagca actctatcag gagatagtga gtgatcctga agtcgctgct
    51961 tttatcaaaa aagaaggttt gactcagcag gaaatcaccc tctccatttc taagtttttg
    52021 gaatatatca gtcagcgtga cctttttgtc aaacaagatg agacttatat tgcaaaaggc
    52081 tatcaacctg ttttggttat gaatgagggc tatgcagatg tgtcctatct tgaaacagag
    52141 gaattggtcg aataccgtcg tttggaagct attaagaacc gcattcagct catcaatatg
    52201 cctcaggctc tcaaaaaagt tactatcgct gatttagatt tcacagacag taatcgtata
    52261 gaggtctatg atgccattga tgcttttgtt gaacaggtcg gcgaacacta taaaggtttg
    52321 tatctatatg gtgattttgg aattgggaag agttttttga tggcttacat ggcccatcgc
    52381 ctatcaacca atcgccacct ctcgaccacc attctgcatt atccgacctt tgttgtcgat
    52441 ataaaaaatg ccatcaaaga tggctctgtc aaggagcgga ttgatgaaat caagctggct
    52501 caggtcttgg tactagatga tatcggagcg gagcaacata gtccgtgggt gcgcgacgat
    52561 gttttacagg tcattcttca ataccgcatg caggaaaatc tgccaacctt ctttacttcc
    52621 aatttctcct ttgatgagtt ggaacggcat tttgcatctg gcaagtctgg tgatgagacc
    52681 tggcaggccc aacgggttat ggagcggatt cgctatctgg ctcgcgattt gcatttgaaa
    52741 ggaaataacc gccgatgaat gaaaccattg atttgatgct gaatcatact tccgtccgtc
    52801 gttttacgga agagcccatt gaggtggaac atttgcaagc tattatatca gctgggcgag
    52861 ctgcatctag ctggaagaat ttccagtctt attccatcat tgtggtgcag tcggagaaga
    52921 aaaaaaggca ctctatgacc tggtgcccca gccagctatt ttacaggctc aggctattct
    52981 ggtttttgtg ggcgaccata atcgtgccag caaggcggct caactccatg gttcagactt
    53041 tgatgccaaa ggaacagaga atctcctgat ttcttctgtt gatgcgagcc tagcagggca
    53101 aaacgccctc ttggcagctg aaagtctggg ctacggcggg gtctttatcg gtatgattcg
    53161 ccataaggcc atggcaatag cagagctgtt caacttgcca gattatacct atcccatttt
    53221 ctgtattgcc ttgggtcgac cagcccaaaa ccatcctgtt aaaccacgtt tggaaagcga
    53281 agccattgtc tttcaggaag aatatgtgga gcaaggcgtg gaagtaatcc aagcctacga
    53341 ccaagttcag acagcctatg caggtgcccg tcagacagaa tcctggtctg agcgtatggt
    53401 tgcccagttt ggtcaggctg aacaaccaga aacaaagtct atcttagaaa agaataaatt
    53461 attgtaaact agaagaggag gagctatggc tctaccaact atcgccatcg ttggccgtcc
    53521 caacgttggt aaatcaacac tatttaaccg tattgcgggg gaacgcattt ctattgtaga
    53581 agacgttgaa ggtgtgaccc gcgaccgtat ttatgctact ggtgagtggc tcaaccgtaa
    53641 gttttccctg attgatacag gtggtattga tgatgtggat gcacctttca tggagcaaat
    53701 caagcatcag gctgagattg ccatggatga agcggatgtt atcgtctttg tcgtatcagg
    53761 caaggaaggt gtgacggatg ctgacgagta tgtatcgcgt atcctttata agacaaacaa
    53821 accagttatt ttggttgtca ataaagtaga taaccctgaa atgcgtaatg acatctacga
    53881 tttctattca ctcggtcttg gcgatcctta tccagtatct tctgtacacg gtatcggaac
    53941 aggggatgtc ttggacgcta tcattgaaaa cctaccagct caggaagcag aagaaaatcc
    54001 agatattatc aagttcagct tgattggtcg tccaaacgtt ggtaaatcaa gtttgattaa
    54061 cgctattttg ggtgaagagc gcgtgattgc gtcgcctgtt gctggaacga ctcgtgatgc
    54121 tattgatacg cactttacag acccagaagg tcaagaattt accatgattg ataccgcagg
    54181 gatgcgcaag tctggtaagg tctatgaaaa taccgagaaa tactctgtta tgcgtgccat
    54241 gcgtgccatt gaacgctcgg atgtcatatt gatggttatc aatgccgaag aaggtatccg
    54301 tgagtatgac aaacgcatcg caggctttgc ccatgaagct ggtaagggaa tgattatcgt
    54361 agtcaacaag tgggatacgc ttgaaaaaga caaccatacc atgaagcagt gggaagacga
    54421 tattcgtgac cagttccaat acttgtctta cgcaccgatt atctttgtgt cagccttgac
    54481 caaacaacgc ttgcataagt tgcctgagat gattaaggcc atcagtgaga gccagaatac
    54541 ccgtattccg tcggctgttc tcaacgatgt tatcatggac gccattgcca tcaacccaac
    54601 accgaccgac aagggcaaac gcctcaagat tttctatgcg actcaggttg cgaccaaacc
    54661 accgaccttt gtggtctttg tcaacgaaga agagctcatg cacttctcct atatgcgttt
    54721 cttggaaaat caaatccgca aggcctttgt atttgaaggg acaccgattc atctgattgc
    54781 acggaaacgg aaataaagag ggcaacctct tttttctttg cacctattcg taaatatgct
    54841 agaatggact tggaggtgtt ggtatggtag cggttccgat ttggcgttct tttttgatat
    54901 tgctttcttt ttcatcattt tttcttgtat tttatgaaga cagtcagtat aaacctttcg
    54961 gctttcgtta ttggctgggg ctagtggctt gtatctggct caatttggtg actttggcat
    55021 cctattttat cgcctttact ggtggttcaa ttatggtcta taatcagtat aaacagccat
    55081 tggttgtgat attccttttt tgtctattcg tggctagtat gctaacctta ctttccttta
    55141 aggctatcaa gatgatgatt cgacgaacca aatattatcg acaggtaaga aaggtaggct
    55201 agtatggaat ttttgggtga gttgctagtt gagtttttga ctggtctagc agacttcgat
    55261 gaaaagaaac accctccctt tggaattcgc tattggctgg gctggttggg agttctgatt
    55321 catgttttac tccttgcctt gcttacttgt gtgactgtct tctttttcaa gtttttcttg
    55381 gttggaaaag gcttgattaa cgtagtagtg gcagttgttt tcctgctatt tgccctattt
    55441 tggctttgga aattcggaaa aacaatcttg aaaatgtggc aagcaacgat ttattattta
    55501 gctattcatt agagacacca gtttacctgc tggtgttttt tgatacctat ttaaacaatt
    55561 caaattgaaa atatgctata atgaaaagat aatattttag atatatttta cagaagagct
    55621 gatgattggt tgaaggataa aggagttaga atgggtcgca tgatgccagg gcggattcgc
    55681 caagaaggaa ttgatttgta cgaggctgga aaactgactg ttcttcatag tgagaatgga
    55741 aagatggtgc tggatattgc tggtgagcgc tttacttacg gcgatgcaga tagcgattta
    55801 cagtgtagtt gccagttatt tcaaagtaaa ggttactgtc aacatctagc tgccacggag
    55861 tattttttaa aaaatgatgc ctcaggcaag gatatgaagc agtctttgaa agaagatggt
    55921 gaacaacata aggaaaccgt ccgtcggact tattttggcg gtctcttttt agatgaaatt
    55981 ttgcggccag aacctgaact ggggattaag tatcagttat cagttgaagg gagcttattg
    56041 ccctatgatc gtcagataga ttggaccttg aaaattaccc gcttgccaga tacacgttcg
    56101 tacattgtgc gggacatcgg agcttttttg cgcattgtga aagccaacgg tcactatcag
    56161 ataggtaaaa attattatga gcaagttact tatgaaaatt ttgatgaacc aagtcaggct
    56221 ctcctggatt ttctctgggc cttggtacca gagaaagttg gtatagattc ggatattctt
    56281 actcattttg gacgacattt tcgtctgcca caagcctatt ttgaggaggg gttggagctg
    56341 ttaaatcagc tagaacattt taacttttcc tatcaacagc agtcctattc ctccttgatg
    56401 gttcttccgt tgacaggtga ggaagggctc tatcattttg aggtgaccgt tcacacgcag
    56461 atgattgaaa tggttattca cgaaaaaaca gtccgaccac tttttcatgg gcgctatctc
    56521 ttagtaaatg gcacggttta tagtgtcaat cgccatcaag aacatctgat ttaccaaatt
    56581 tccgaacttg ttccaaccga atcaggtttg agaaaagtgc aggtagattt ccctgaccaa
    56641 aatcgtctgg ctttaagctt gctggatttg cagacaattg ggactgttaa ggcacctaaa
    56701 cgcttcatca ttcatgattt caagccagaa tttcatattc agatggaggc aaatgacagt
    56761 ttatcactcc aattggtttt ggattttgat ggacgtaagg taaggagtga agaggatttg
    56821 gctctcctgc cttttgccag ccatttccaa catttggaga gggtctatca ggctattcgt
    56881 ttagctggct ttagggggac atatcatgcc cagagagcgg ctcttagtca gcaggagctc
    56941 tatccatttt tccaacaaca attgcctata ttacaaaaaa tggggcaggt tcatctagca
    57001 gaaaggctac aggctttata tattgaagcc aaacctcaat tagaaattgt gcgtaacggc
    57061 tcacttttgg atatttcgtt tgacttatca ggtattgaac aatctgaaat cgatcaggcg
    57121 attacagcct tgttgaatca agaggatcac tatactagcc cgagcggtaa ggtatttgtt
    57181 tttgatgagg aaaccaagaa aatcagtcaa accctaatct atttgcgggc ccgtcatggt
    57241 aaggaggggc aggtacaagt ccatgctctt gccggttacc aattggctca atccttgtca
    57301 caattcaacc aagtcagttt ctccaaggaa tttgaggaaa tggcaagcta tctagctcag
    57361 ccagatttgt tcccgcttcc tgctgtggaa gtaacaacgt cgcttaggga ttatcagcag
    57421 acagggctta agtggttgac tatgctggat acgtatggtt ttggcggaat tttagctgac
    57481 gacatggggc ttggaaagac cttgcaaact atcgcctttc tgtccagtcg gatgacaaaa
    57541 gattccaaag ttttaatatt ggcaccgtct agcttgattt ataactggtt agatgagtgt
    57601 aagcggtttg ctccaagttt agatgtggct gttgtccatg gaaacaagga acagcgtgaa
    57661 gagatcattg ccaatgatca ccaagtctta gttacctcct atccatcctt cagacaggat
    57721 gttgcactct atagacagga acgctttgac tacctcattt tagatgaggc gcaggtcatg
    57781 aagaatgccc aatctaagat tgcacagctt ctgcgtgagt ttgaggttgg gaattgcttt
    57841 gccctctcag gtacgccgat tgaaaaccat ttgacggaac tatggtccat tttccaaatt
    57901 gtcttaccag gtttattgcc aggcaaacaa gacttcggta aattagcagc caaggacatt
    57961 gcgcggacca ttcaaccctt cgttctcaga cgtcataagg aagacgttct tcaggaattg
    58021 cctgatttga tagaggtcaa tgtacttaat gaactgacag atgaacaaaa agctatctac
    58081 ctagcccagc ttcaacaaat gcggactcaa atagctggcg cagatgatgc tcaaatcaat
    58141 cgtagcaaga tagaaatcct atcaggaatt actcgcttac gtcaaatctg cgatactccc
    58201 agccttttca tggaagagtt tagtggtgag agtggcaaac ttaatagttt gaaagaatta
    58261 ctcttgcaac taaaagaagg tgaacacagg gtcttgatat tttcccaatt cagaaatatg
    58321 ctggaaaaaa tagaagaaca gctgatagaa attgggatga cttcctatac tctgactggt
    58381 tcaacccctg ctaaccaacg ccaagaaatg acacaggcct tcaatgcagg aagtcgagat
    58441 gcctttctca tttccttgaa agcaggtggc gttggcttga atttgacagg ggcagacaca
    58501 gtcatcctag tcgacctttg gtggaatcct gccgtggaag ctcaggctat cagtcgagct
    58561 catcgcatgg ggcagactga aaaggttgaa tgctatcgcc tgattactag agggacaatc
    58621 gaagagaaga ttcaagaatt acaagaaaat aaaaagaacc ttgttaaaac agttcttgat
    58681 ggcaatgaaa gccgagcgaa tttgacggtt gaggatattc gtgagatttt agggattgag
    58741 tgatatggaa tcagttgact cagcgtagaa ttaggaaata aggcctaagt atggtataat
    58801 aagggttcga aaggatgact tatgattaga catgaaaaaa gatttccact agtcgcagat
    58861 gatgaggtac tagttggaga aaatccaatt atgagtttat atgatgagag cgacctgatt
    58921 agcaatatca ggggacctta tcaagaaaag gaatttagct ggtctaccga ttcacagcga
    58981 gttgcgtcgg caaaaccagt agcacaaacg gaagatgagc tcctgcctcc tctgtttgaa
    59041 gctaagccaa gccattattc tcgcaaggaa cgccttcagc aactgactaa aacgaagcct
    59101 tctccagtga aaacacaggg gcagttggct cgtgaacagg ctagagaaga cttgaagaaa
    59161 aaacgatcag caacctactt aagagatgaa aaaccagcac cagctaaagt tgtggtgaaa
    59221 cctcctgtcg tttcaacagc tgaatctaag gcaggtcggt tgacacgttt ggcggacaac
    59281 ctacgtcaga cagactatat tctcgctgat atgccagctg tctattcttt gaagaaagaa
    59341 gatagagaac aggagcaggt tataaagaaa aattcgtatg actttttaag aaagagtcag
    59401 gtttacaatt atcctgagcg cagacaacaa cgagatcgcc aagtggcaca agaattgaat
    59461 ttgacacata tagaagagga ataacatgac aaaaacctat cattttatcg gaattaaggg
    59521 atcgggtatg agcgcacttg ctcttatgtt gcatcaaatg gggcataagg ttcaaggtag
    59581 tgatgtagag aaatactact ttacacaacg cgggcttgaa caagctggga ttcagatttt
    59641 accgtttgat gagaaaaata ttacagcaga tgttgaattg attgctggta atgcttttcg
    59701 tccagataac aatgtggaaa tcgcttatgc tgatgcccag ggctatacct acaaacgtta
    59761 ccatgaattt ttaggtgaat ttatgaaagg ttttacgagc ctcggtgttg ctggtgccca
    59821 tggtaagacc tctacaacgg gattattggc acatgttatg cgcaatatca cagatacttc
    59881 cttcttgatt ggtgatggta ctggtcgcgg ttcggcaaat gctcagtatt ttgtgttcga
    59941 atccgatgaa tacgaacgtc actttgcccc ataccatcct gaatacagca tcattaccaa
    60001 tattgatttt gaccatccag attatttcac tagtctagag gatgttttca atgctttcaa
    60061 tgattatgcg aagcaagtaa aaaatgctct cttcgttttt ggtgaagatg agcaacttcg
    60121 tcgtatcacg gcaaatgctc caatctacta ttatggcttg gaagacaata atgattttgt
    60181 tgcctatgac ttgaagcctt ctacaagtgg ttcacaattc aaagttcgcc atggtgaaga
    60241 agagttggga aaattccaaa ttccaacctt tggtaagcat aatgtgatga atgcaacagc
    60301 tgttattgcc aatctctata ttgctggatt tgatttgcaa ctggttgcag aacacttgaa
    60361 gacatttgga ggtgtcaaac gtcgctttac ggagaaaatt gtcaatgata ctgttatcat
    60421 tgatgacttt gctcaccatc caacggaaat cattgcaacc attgatgcgg cacgtcagaa
    60481 gtatcctagc aaggagttgg tagccatctt ccaaccacat acattcactc gtaccattgc
    60541 gcttctcgat gagtttgcag atgctttgaa tggagcagat gcagtttacc ttgctcaaat
    60601 ttatggatca gcgcgtgaaa cagacaatgg tcaggttaag gtagaagatt tggcggctaa
    60661 aatcaacaaa aaaggtggac ttgttacagt tgaaaacact tcaccacttt tagaccatga
    60721 caatgccgta tatgtattta tgggagctgg tgatattcag tcctatgaat attccttcga
    60781 aagactcttg tcaaatctta caaataacgt ccaataaaaa gaaagacgga ggcctatggc
    60841 ccctgttttt ccgctatata agggagaaaa ttatggaaat tcgttttgct actccttcgg
    60901 atttagaaca ggttgttttg attgaaaatg ccaatttttc taaagaggaa cggatagctg
    60961 agtctgttct tgctacttat ctgaatactt tgagtaaaac ctgtttaata atggaacacg
    61021 atgaggaaat agcaggatat ttattatcct gtccctctgt ttcgcagact gttacagacg
    61081 atatttttta cttgacagag agtgacatgc cgacaggcgg tcacctagct attgccagtc
    61141 tatccgtagc ggatgcctat aagggacagg gagtgggaac tcttttgttg gcagccataa
    61201 aagaagtggc tttagcggga ggatttgaag gagtttccct gacctgtaag aggtatttga
    61261 ttagctacta tgaaatgaac cagtttgaag attttggccc ctccttgtcg caatttggag
    61321 gacaaaggtg gagtgatatg tactggaaag ccttgtagaa agggaagttc ttgcaattca
    61381 taagccttta agatataatg tatagtaact gtgtgaaagg agtaacagcg tgacaaagga
    61441 tacgaatgaa aaaaacacgc agtcttcagg cttccgcgat caaattttac gagatttgga
    61501 agaattgaag gtgaaacgtt tggcggaaca gtcagcggat gttcttgttg ataagcgtaa
    61561 tgaagttatc aatgagctcc agcctagtct tgccgaagaa aaagcccccc atagagagac
    61621 tgaaattgta aaagtagaag gtattgcttt ccctgattca tacttgtcag aagaacagca
    61681 agaatcagaa gtgatgacgg aaagtattga agagccaaca tcagaaactt tggctactcc
    61741 agagactttt gtgattgaaa aagaagttgt ttcaagtcca gttccacaag atactgttga
    61801 acgaaacttg gagaaattaa ggaatcttgt ggctgctaat acggcaggat ttgatgaagt
    61861 accatcaagc tcgtcagttt ctgagccagt agagtctgtc ctttcagaga agtcttcttt
    61921 ggaagataca tttttggaat ttccaacgga agatgtatca gctgtaacgg gtgatacaga
    61981 aatcatcgca ctagaggaaa ctattattgc tccaaagaca acggctattg ttccagaagt
    62041 agacaagcag atgcaggaaa cacaacccag aagaagaaca acccacagaa caagcaagca
    62101 acgtcgtaaa aaacaagata atgccgctaa acacattgtc tctgttatca tgtcgattgt
    62161 tgtagtggca gtcctagtga caggtgttac tggctatatg tgggtaaaat ctagtctgga
    62221 accagttaat gcaaaagcta cagaaactat tcaggtagag attccagaag gatcttcaac
    62281 tttagaaatt ggtaaaattt tagttgacaa caagttgatt aagaatgcta ctatttttaa
    62341 ttactactct aaaattaaga gttataataa tttccaaagt ggtttttata atttaaaaca
    62401 aaatatgtct gtggatgaca tcgccaaagc acttcaagaa agcggaactc cgacagctca
    62461 aaaagaagct gcagggaagg ttttgattgt tgaagggtat acattaacac aaattgctca
    62521 ggctattaca gacaatacta atacaaaaga taagaacgat aaaacaccat ttactgcaga
    62581 acagtttatg gctactgtga ccaaccaaga ttttattaat cgaatggttg ctacttatcc
    62641 aaaattgttt gccagcttac cagctgctga tagtggagtt atttatcagt tggaaggtta
    62701 cctcttccca gcggtttatg aatacagcga tgaaacaact atcgaagagc tcgttgagca
    62761 aatgattgcc gcgatggata atcgtttaca accatattat gaaacgatta ctgctaagaa
    62821 tttgactgta aatgaagttc ttaccttggc atctttggtt gaaaaagaag gttctactga
    62881 tgaagatcgt cgaaacattg caagtgtctt ctttaaccgc ttgaatgcag caatgcctct
    62941 acaatctaat attgcaatct tgtatgctca gggtaaactt ggtcaagaaa caactctagc
    63001 agaagatgca gcgattgata catcaattga gtcaccatac aacatttatt ggaccccagg
    63061 attgatgcct ggaccagtgg atagtccaag cctttcggct atcgaggcag tgattaatgc
    63121 caacacaaca gactatcttt actttgtagc agatgttaca actggaaatg tttactttac
    63181 aaataatatt gatgaacata accaaaacgt tgctaagtat gtaaatgcac atcttaataa
    63241 tgagtaaatt cttaaaacaa aattatgtgg ttttccacat aattttgttt tcatgaaaaa
    63301 taaaagaaaa ggaaagacaa atggcagaaa aaacatatcc aatgaccttg gaagaaaagg
    63361 aaaaattaga aaaagaacta gaggaactaa agctagttcg tcgaccagaa attgttgaac
    63421 gtattaaaat tgctcgttct tacggagacc tttcagaaaa ctctgagtac gaagcagcta
    63481 aagatgaaca ggcttttgtt gaaggtcaaa tctcaacaat cgaaacaaaa attcgctatg
    63541 ctgaaatcgt aaacagtgat gcagttgctg cggatgaagt agcaattggt aagactgtga
    63601 ctgttcaaga agttggtgag accgaggaag aagtctatca tatcgttggt gctgcaggtg
    63661 cagatgtctt tgcaaacaag atttcaaacg aaagcccaat tggccatgct ttgattggta
    63721 aaaaaacagg agatgttgca acaattgaaa cacctgctgg tagctatgat gtaaaaatct
    63781 tgaaggttga aaaaacgaaa taaggtgtgg agagagtcga aagattctct ctttttgtat
    63841 agacaatatg taaagacctc taattgagtg tggtaattcc tgttagaagt tgattatttt
    63901 tttattctag tgtacaggta aatccacgaa ttctcaactg gggatcttta catagtgtct
    63961 atataagaaa acaaccatct gaaatagatg gttgcgattt tttatctaga acgttgttta
    64021 ccggcgttac ggtttctctt cttgttagat gtcttttctt caataactgc tgaagcagtt
    64081 ggagtaacgt ccttcgtttt acgaggagtt gctgacactg tgatattttt gaattcctct
    64141 tccacttgtt tacgaatacg aggtttcaaa atgaagtttg taatagcttg ttgaagaata
    64201 ccgaagagac caccgacaac ccagtagaga gtcactccag caggagaccc aaatgagaac
    64261 atcatgatca taattggatt catcagagcc atggttttca tttgtttttt ctgttcttca
    64321 tccatgccga cttgcattaa gagcgattgg gcatagtata aaataccagc aacgactgtc
    64381 aaaatcaggc tagttgaacc taaattaata ccaaggaaag tagcttctga aattcctggt
    64441 gtgtggcgag ccgcaaagta gattgcagag aagaatggca tttgaatcag catcggcaaa
    64501 caaccgattc cgccgagcat gctcacaccg tattgttttt gagttgcaaa atactcttgt
    64561 tgcgcagcaa gttgctcttc ttgagagctt gcatttttca tgcgctcctg gattgggcct
    64621 aaaatcggtt tgagataatt catcttctca gattggatag cagctttcca agattggtaa
    64681 attcccaatg ggaggatgat gaatcgaacc aataaggtga cgatgataat agcaagacca
    64741 aatcctagag cttgatcttc tgcaaaaaag cgaatcaagt tggacattgg ttgtcccaac
    64801 caatcccaaa tgggacctgt aggatttccg cttttatcag tttgaacaca accagataag
    64861 aaaagaagag ttgataaggc catgcctgac aagatgagta gacgtttatt tttcaatttt
    64921 tttcgttcct ttgttttttt cagtatactc tctattttac tttttttgac ggaaatatac
    64981 aagttttatc tatagctaac ctgaaaatcc ttatagtcct caaaattggc tagggtgaca
    65041 tctagataga tgactttggc catacgagaa ggccctttcc gaatttcatg gataaaatgg
    65101 ctgagcttct cagcattatc tgactgagct aaaatggtga cagtcccatc atcattattc
    65161 caaactctgc cgtagatgtc gcctatttcc acagctaaaa attgaacaga ccaacgaaag
    65221 ccgactcctt gcacacgacc agatgcaatc atttttacct ttcgcataag tttctccttt
    65281 tgacaagaca tttactttat tatatcatgg ttgggtaaga ctgttcaaaa atcaagataa
    65341 ttgatttagc cgttggaaaa ttgaagttgc tgagcagtaa aagaaaaggg gcattcatgg
    65401 agatcattcg ctcaaaggcc aatcatttgg tcaagcaggt taagaaatta caacagaaaa
    65461 aataccgtac ttcttcttat ttgattgaag gctggcattt gctggaggaa gcgatggagg
    65521 ctggagccaa tattgagcat atttttgtgg tggaagagta ttttgaaaag gttgcaggtt
    65581 tagccaatgt gacagttgtc agtcctgaaa ttatgcaaga attagctgat tctaagacgc
    65641 ctcagggggt agtagctcaa cttgctttgc cgagccaacg tttacctgag actttggatg
    65701 gaaaattttt ggttcttgaa gatgtgcagg accctggaaa tgttgggaca atgattcgta
    65761 cagctgatgc agctggtttt gatggagtat ttctatcgga taagtcggct gatatttata
    65821 atatgaaagt gcttcgttcc atgcagggga gtcacttcca tttgccagtt tatcggatgc
    65881 caatttcctc cattcttaca gctcttaaaa gcaatcagat acaaatattg gcaacgaccc
    65941 tctctagtca gtcggttgac tataaggaaa ttacgccaca ttctagtttt gccttggtca
    66001 tgggaaacga aggtcaggga atttctgatt tagtggctga tgaggcggat caacttgttc
    66061 atatcaccat gccagggcag gcggaaagcc tcaatgtagc aattgcggcg ggtattctat
    66121 tgtttagctt tatttaagcc aattgtacta tagtgtggta taatattcca acgaggttaa
    66181 cgaatggttg catataaaca agataaagaa tacatgcatt acgtggggca cttgattgcc
    66241 acacccaagg tgcaaaaatt ggggaaaatt cctcatcatt atcactccac gcgcttggaa
    66301 cattccatca atgtctctta tacaagttat aagattgcga aaaaatttgg ttgggatgcc
    66361 aagtcaacag ctcgtggtgg tctattgcat gatttattct tctatgactg gagagatacc
    66421 aaattcaaca agagccatgc ttgggttcat ccacgaattg ctaaacgcaa tgctcagaaa
    66481 ctcattcaac tcaataaact agaagaagac atcattgtga agcatatgtt tggtgcgaca
    66541 atcgctcctc cttgctacaa ggaatcctgg attgtgacat gcgtggataa gtattgggct
    66601 gtgagagagt ggagtctgcc cttacaacac aagtggaaaa atcgtaaggt ctttcggttt
    66661 caataagatg atttaaagga gaatagtatg aataacgatt catttattat taatcaggtg
    66721 gataataccg ccctcaaccg tttcttcggt aaaatttatg gtgtggttgc catgggaatt
    66781 ggtctgtcag ctctagtttc tttcttggct gtgaccgtct ttcaatcttt attgcttagt
    66841 ctgctgagtg caggttccat catcatgatg ctgattatga ttggtcagat tgccttggtt
    66901 gtttctgctt cagcaatggc agctaaaaat agcccaatgg ctctaccaat gtttcttgcc
    66961 tactcagtaa caaatggtat caccattagc atgattttga tgttctatac tagtgaaaca
    67021 gttgtgcttg cctttgtgtc agcggctctt atgtttgcta tcatggctgt aattgggatg
    67081 acaacgaaga aggatctttc tggtatggct caggcattgc gtgcagctct atggggaatt
    67141 attattgcaa gtgttattaa tatcttcctt cgtagctctg gtctaagctt tatgatgtct
    67201 atcatttctg ttttggtatt ctcaggtttg attgcttatg acaaccaacg tatccgcaat
    67261 gttttcgaac aaactggtgg taatgttggc caagggtggg tcgtatccat ggcgcttcag
    67321 ctctatcttg acttcatcaa cctcttcctc aacctactcc gtatctttgg tggtttgagt
    67381 agagactaat tatgacatat aaaaaagagg atttacctct tttttatatg tcgtttgtta
    67441 tgctagagct cccattggat cccatggggc aaggacttgt ggttgagctt gataagctgc
    67501 tagttcttct tgtgtgagga attcttttcg gacaacaatc tgataagtgt actcgtccat
    67561 ccagctatct gatgcgacga agtatccctt gtcaccaacc ttgtcacccc aagagttttc
    67621 tactttccat ttgagaggtt gctcattgtc atctaaatca acaccagtta agaccatggc
    67681 gtgggtcatc aagctttcgg agtagtctaa tcttccagcc ttgtcttgat ggaaatggat
    67741 acccagacct gaagagaagt cgtaggtgtt ggttgccatg atacctgttt ggcgattgct
    67801 gctttgaccg acatcggaac caaaccaaac ggactcacca gctttgagtt gggcaatagc
    67861 tagttcttta aaacggttca tttctacatt gaggtagcgg acagcagggg caccaacgac
    67921 gttccccaat aattcgactg tataagattt attgtagggt ttgtcagttg taggagcatt
    67981 gataatggag acatagtcag atagtttcaa accaacgtat ttctcgtaga atgcctgagg
    68041 tgtcacattt gtatcgcggt gatagacatt gtctttatct ctatatgcaa aatcaaagct
    68101 acgtggaggg aggccaaggt tgacggctag gaagttaaag atttcttgaa gcaagttttc
    68161 tttttgtgtt tgaacctctt ccggagaagc tccttttgca aggaggtctc gcaagatttg
    68221 tgcatcttga cggagcaatt tgttaaggta ctgattgagc tcacggctgg cactggatga
    68281 gatagattct ggatagacgg attttggtac cacaccatat ttttcaaata aggccacaac
    68341 catatcccat tgaccgccat cttgttgagg ggtatccaat aagaatttta ccttacggct
    68401 accaatttct tggtcagctg tagcaatgat ttgttcgagg aaccagttgg acttttcata
    68461 tttatcccaa aagaaggtat gggcctgtga tagctcaaaa ttttccagtt tgaagtcaga
    68521 gatgagttta tggcggaagg tgtttaatgc agcaaacatc cagcaacgtc cagaagcctt
    68581 ttggtttgaa acagcgtcct tggtcaagtc gattgaaaag acatagtcat tgtcgatggc
    68641 gctttggcgt gtttctaagg atttcaaaag tccgttgtgg ctaacggcat tttcggttgc
    68701 ctgtaggctt ggattagcta gatagttggc atataagcgt tctgtaaaat caaaatctaa
    68761 tgttgacata tattactcct tttttaatga taatcacatt atagcgctca taatttattt
    68821 tgcaagtatt tggtggagtt gaaagctaca gttcctcaca tatttgtgat ataataggaa
    68881 aaatatttga tgaggtagtg acatgaccaa gacaccattt gttagtaaag aagttttaga
    68941 aaacattacg gagcaatttc cgactccttt tcatttgtat gatgaaaaag gcattcgtga
    69001 gaaggcccgt gcccttaatg cagctttttc atggaacaaa ggctttaaag aatattttgc
    69061 ggtcaaagcg acaccgacac cagcaatttt aaaaatcttg caagaagaag gttgtggagt
    69121 ggactgtgca acggatgtag aagtgctgat gagtgaaaaa ttgggcttta aagacatcat
    69181 gttcacatct aatgacaccc aagcgcaaga gtttgtttat gccagaaaag ttggggcgac
    69241 cattaacctt gatgcctatg agcatattga gtttttgaaa aatgttgctg gtatcccaga
    69301 aacggtctgc ctccgttaca atccaggtgg ggtcttctcg ctgggaacgg atattatgga
    69361 ccacccagaa gagtctaagt ttggcatgac caaggaccag ctcatgaagg gctacaagga
    69421 attaaaagaa ctaggtgtga agcagtttgg tattcatgcc tttctagctt cgaatacagt
    69481 aacaaatgac tactaccctg tcttagctcg tcaactcttt gaattggcct tggaaattcg
    69541 tgaggaaaca ggtgtgacct tggacttcat caacctatca ggtgggattg gagtcaacta
    69601 ccgtcctgag caagaaccaa acgacattgc tgtcattggt gagggagttc gtaaggttta
    69661 cgaggaaatt ctcacaccag ctggtatggg acatgttaaa atctttacag aattgggtcg
    69721 ctttatgttg gcgccacacg gtcacttgat tacaaaggtg ctccatcgta aggaaaccta
    69781 tcggacttat attggtgtcg atgcatcggc agccaacctc atgcgtcctg ccttctatgg
    69841 cgcctaccac catatcacca atatcacgcg cccagatgcg ccaatcgaag tggtggatgt
    69901 ggctggttcc ctttgtgaaa acaacgacaa gtttgcggtc aatcgtgaat taccacgggt
    69961 agaagtagga gacaccttgg tcattcatga cagtggggcc cacggcttct ccatgggcta
    70021 caactacaac ggtcgtctgc gttcttctga aatccttttg caggaagatg gcacagcgcg
    70081 gatgattcgt cgtgctgaaa caccagaaga ctatttcgca actatttacg gttttgattt
    70141 tgacaggtaa gtcttggaaa agactaggga atttggtata atagggttat tgaaagattg
    70201 ttaaaaacaa tcagaagtat actttttaga agagtcagga gattgacaga tgaacttagg
    70261 tttagctatt ttacttattg tattggcatt tgcaggtggt gtggccttgg gtatttactt
    70321 gtcacgcaga caggtagaaa actacattgc tgataaacca attttggatg agaatgcttt
    70381 gcgtttgatg atgagccaaa tggggcaaaa accaagcgag gcaaaagtac aacaagtact
    70441 tcgccaaatc aagagccaac aaaaagtggc aagcaagaaa aaataatcaa actgggactg
    70501 ggatattcat tcccagatcc cattttttga gtagaaaaga aaggctagtc agattttctg
    70561 gctattctca gtattatgga taatcgacca ataggttttt tagattcagg tgttggggga
    70621 ttaacggttg cgcgtgagtt aatgcgccaa ctaccccatg aagaaatcgt ttatatcgga
    70681 gattcggcac gggcacctta tggaccccgt ccagcagaac aaatcagaga atatacttgg
    70741 cagttggtca atttcctttt gacaaaaaat gtaaaaatga ttgtctttgc ctgcaatacg
    70801 gcaacagcgg tagtctggga agaagtcaag gaaaagttgg atattcctgt tttgggtgtt
    70861 attttaccag gtgcttcggc agctattaag gcaacgcaaa ctggtaaggt tggtgtctta
    70921 ggaacggcta tgaccattca atccgatatc tatcgtgaaa aaattcaggc cctttctcca
    70981 gaaacgcagg tagacagcct agcctgtccc aaatttgcac cactggttga gtccaatagc
    71041 caccaatcca gtttggccaa aaaggttgtt tatgagacac ttcgaccact tgttgggcaa
    71101 gtagatacct tggtcttggg atgtacccat tatcctctgc ttcgccctat catccagaat
    71161 gccatgggca aggatgtcaa gttgattgac agtggggcag aatgtgcgcg agatatttct
    71221 gttttattaa attattttca aatcaaccgc agccgtaccg aaaaggatat tcagcacaga
    71281 ttttacacaa cagctagtcc ggcagctttt aaagaaatag ctgaaagctg gatgggcatt
    71341 gatattcatg tggagcatgt agaactatga cagacaagat atacgaatac agagatgaac
    71401 acaattggtt tattggaaaa gccagctttg ccaatctatt tggttcattt ggtgaaaatg
    71461 gcagagagca ggaaatttac cagattggtc aattgtttga caaactaatt gctggtaatt
    71521 atgaagatga gaactttaac cagtgtgtca acattgaagt gatcaaactt cagtctgaat
    71581 ttgccctctt tcaatttgcc tgtgatactt tgaatgagtt aaacaatcgt cagttcaagg
    71641 ccctccaaca ccaaggagct attctggtaa ctgagaatga caaacttctc ttggttcatc
    71701 tgccacaagc aggggttagc acggcagatt tcttcggtca agacaaggga ttggcaagcg
    71761 tgggagatac catcttgatt gccacaaaaa atgaaggtaa gactaaggaa ttccgtaagt
    71821 tttttgagcg ttttggctac caggtcgaga acctcaacaa ctatcctgac ctgccagatg
    71881 tagcagaaac aggtatgact tttgaggaaa atgcacggct caaggctgaa accatagcag
    71941 agctgacagg caagatggtc ttggcagatg attctggttt gaatgttgat gctttaggtg
    72001 gcctgccagg agtttggtct gcccgttttt caggtccaga tgccacagat gagctcaata
    72061 atgccaagct cttgcacgaa ttggccatgg tatttgaact gaaagatcgt tcggcacaat
    72121 tccattgtac tctggtcatg gctgctccaa atcgtgatag tttggttgtc gaagcggact
    72181 gggaaggctt tatcggtatg gacctccgtg gggaaaatgg atttggatat gatccacttt
    72241 tcctcgtagg cgaaacaggt aagacctcgg cagaattaac cctagaagaa aaaaataaga
    72301 tttcccaccg tgcacaagca ctagaaaaat tagtggaggc atttccagta tggcaggagc
    72361 aagcaaaaca atcctagtca tgagcgactc tcatggggat agacagattg tagaggatat
    72421 taaacatcat tatcttagca aggtcgatgc catctttcac aatggtgatt cggagctgga
    72481 tagtcaagat agtttgtggg acggcattca agtggtcaat gggaactgcg actattttgg
    72541 tggttaccct gaccagctca ttactcaatt ggatggtgtg actatcgctc agactcatgg
    72601 tcatctttat ggcattaatt acggctggca gcggttggat tattgggccc aggaagttga
    72661 tgcggatatt tgtttgtatg ggcatctgca tgtgcctgat gccgaagtgc gtggcaagac
    72721 cctcttcctc aatcctggct ccgttagtca acctcgtggt ttggtcagag aatgtctcta
    72781 tgctcttgtg accatctatg atgatcactt ccatgtggat tactacaatc gacagcacca
    72841 actttaccca gcattgacaa aggatatttc aagatgattg caagagaatt tgaagccttt
    72901 ttattggacc aggaagaaac tttcttgaca ccagcggata aattggcagt aattattgat
    72961 acgcataata ttgaccatgc aaaactgtta ctcagtcaca tgacctattc acgcgtacct
    73021 gtggtaacag aagatggccg cttttttgga accatcggct tgacggaaat cattaaatat
    73081 caagctgaaa atgaactatc ggatgatgag ttaaacagag atatttctgt gattgtaaag
    73141 acagatgaag agacggttgg tctggattat gatttgacag aggtgatgcg taagctagta
    73201 gatcaatctt tcttacccgt ccttggggaa aatagagaat ttatgggaat cattacacga
    73261 aaatccatct taaaggcaat caatgctctc ttgcataatt tccccctagc atcaaaagaa
    73321 ggcaagaaat gaagcaggcg attgaatctt ttatccagag caaaaaggtc agtgtcaaca
    73381 gccaaaagtc ctatacctat gacctgcagc agtttgtgac agtaacaaag ggggagatta
    73441 gccaacagtc tcttttggtc tatcagcagt ctcttctaga cttgaaacct gctgctcaga
    73501 aaagaaaaat gtcagcggtc aatcaatttc tctactttct ttatgaaaat aatctcctgg
    73561 atcgttttta taaattgcaa acgacgtcag gtccagccag cgtcaaaaag aaactggagc
    73621 gtgaggattt aactctcctc tttcaagaaa gtccttggct agaaggtcag ctcatcgcac
    73681 ttttgatagc atatttaggt ttgacgccaa gtgaaatagc agagctgact agtcagcagg
    73741 tcaatctgga ttttcaagtc ctgacagttg agaagggagg agccaagcgg gtgctcactc
    73801 tgcccaagga attgataccc tatatggagt ctcatctgtc tggacgctat gtcttcgata
    73861 agaagggaca gacctattct cgtcaatggt tttttaatcg tctgacagaa tttgtccagt
    73921 ccatcggcaa gcctgattgg acagcccaaa aattgcgaga gcagtatatt ctaaaacaga
    73981 tagacgaagg aaaatccttg gaccaaatcg ccaagcagtt gggactgaaa acaagcatga
    74041 gtttggaaaa atttagataa tggatataaa attaaaagat tttgaagggc cacttgatct
    74101 cctgctacac ctggtgtcca agtatcaagt agatatttac gaggttccga ttacagaggt
    74161 tattgagcaa tatttggcct acattgctac cttgcaagcc atgcgtttag aggtagcggg
    74221 agaatatatg ctcatggcta gtcaattgat ggtcatcaaa agtcgtcggt tattgccgaa
    74281 ggttgttgag caaattgatc ccgaagatga tcctgaaatg gacctcttgg accagttgga
    74341 agaataccgc aagttcaaac ttctcagtga gaaattaggg gagcaacatg atgaacgggc
    74401 caactatttt tcaaaaccca aattagattt gatttatgat gatgtacagt tagccaagga
    74461 taagaccgtc attgacattt tcctagcttt ttctaaagta atggctgaaa aacaggcaag
    74521 cctccgtcag tctcatgcga ccattgcccg tgatgaatat aaaatcgaag acatgatgga
    74581 ctttgttcgc agtcgtttcg agactggtcc acgccttgaa ctccgtcagc tttttcaaga
    74641 aagtcaagat gtcaatgaaa tgattacgat cttccttgcg actttggaat tggtcaaggt
    74701 tcatgaaatc gtcctggagc agacagagac ttttggagat atttatctag taaggagtga
    74761 agatgaatcg cttagctgaa atcgaagtcc tgctctttgt ggcaggtgag gatggcttga
    74821 cgttacgaaa tttggcagag atgttggaaa tgcagccgac agctgtcagc cagcagttag
    74881 agaaacttag tgagaaatat atggcagaca aagcctcagg cttagccatc ttggagtctt
    74941 ccaatcgcta caagttggtt actaaaaaag aatatgcaaa ccttttgcga atctatgcca
    75001 aaacaccaat caatcagact atgtcacggg ctcttttgga aaccttatca atcgtagcct
    75061 ataagcaacc cattactcgg attgaagttg atgatattcg cggagtcaat tccagtggtg
    75121 ccatcagtaa attacaggcc tttgacctca ttcgtgagaa cggtaagaaa gaggttcttg
    75181 gtagaccaaa tctctatgtg acaacggatt atttcctgga ttacatggga attaatagtc
    75241 tagaagaatt gcctgatgtg tctgaaatag atttgattca agaggaaaca gagctattcg
    75301 tagaaagaaa tgagttagaa aatgagaatt aataaataca ttgcccatgc tggagttgcc
    75361 agtcgtcgta aggcagaaga actaatcaaa caaggactag ttactgtaaa tggtcaggtt
    75421 gttcgtgagc tagggacagt tatcaaatcg ggtgataagg tagaggttga gggacaacca
    75481 atttataacg aagagaaggt ctactatctc ctcaataaac cacgaggtgt tatttctagt
    75541 gtgtcagacg acaagggaag aaagacagtt gtggacttgt tgccaacagt taaggaacgg
    75601 atttatccag ttggacgtct ggactgggat acatctgggg tcttgatttt gaccaatgac
    75661 ggtgatttta cagacgaaat gattcaccca cgtaatgaga ttgataaggt ttacttggcg
    75721 cgtgtcaaag gggttgccaa caaggaagtt ttgcgtccct tgacccgtgg tgttgtcatt
    75781 gatggcaaaa agactaagcc tgcggtgtat gagattataa aggtggaccc tgttaagaac
    75841 cgctcagttg tagaattaac aatccatgaa ggtcgaaacc accaggttaa gaagatgttt
    75901 gaggctgtcg gcttgcaggt agacaagctg tctcgtactc gctttggtaa tcttgacttg
    75961 accggcctac gtccaggaga ataccgcaag ctcaataaga aagacatcag taaactacat
    76021 accctggccg ttactaagcc agttaaaaaa taatgactag acttttgatc ggcttggtcc
    76081 gattctatca gaaatttatt tctccccttt ttccgccctc ttgtcgctac cgtccaactt
    76141 gttcggctta tatgatcgag gccttacaaa aacatggact caaaggcttt ttgatggggt
    76201 tggctcgaat tggtcgctgt catcccttgg tggaaggtgg agaagatcct gtgccggaca
    76261 ggtttagttt gaaaagaaat aagcagaagt agggcaacct actttttgtt ctgtataaat
    76321 ataggttttt aggttgcctt tagtactctc tcaaaagatt tgggagcctt ttaaggctgg
    76381 agatagggcg aagcaagttc gcctcaatat taacagtcca ctggactgta aaagccaatc
    76441 aatcactgcg ctcagatgtt gacacgaact ctgagaagca aggttggtct ttctgcccag
    76501 cctccatgat tttctatgaa aatttgaaaa aaatggggca aaactcttga ttttcagcct
    76561 tctttaagct acaatagtat cacgatttca ttgatttaac tcaaacctgt tgtgagttaa
    76621 gtgaatgaat catcattcac catgctgttt gctgagcttg actccgggca gtgtggctat
    76681 ttttttgtct ttcttgccat aggagacagt cgagtctttt tactcaatga aaatcaaaaa
    76741 aagaaactag acaacaagca acagaccgta ctggtatacg gcaaaatgaa gctgacaatg
    76801 gtttggattt gattttcgaa gggtattcgt gtttagtgaa atgtcaccag agaggttctt
    76861 atgaatattg aaacattaga gtatatagaa gaaacagcca aaaaccacat tgtcttattt
    76921 gaaccacaga ttccacagaa tacaggcaat attgctcgaa cttgtgctgc aaccaatagt
    76981 cctctccata tcattaagcc tatgggattt ccaattgatg accgtaagat gaaacgtgca
    77041 ggactagatt attgggataa gttagatgtt cgcttctatg acaatttagc agaattcatg
    77101 gattatgcca gcaaacaagg acgtgttcac ttagtatcta aatttgctga taaaacctat
    77161 tcggatgaag actataatga tgggaacatt cattatttct tatttggtcg tgaagataag
    77221 ggcttgccag aagattttat gcgtgaacat ccagagaagg ctatccgtat tccaatgaat
    77281 gatgaacatg tgcgtagtct taatgtctct aatacagcgt gtatgattgt atatgaggct
    77341 cttcggcagc aacagttcgc tggtctagat ttggttcaca cctatgatgg ggacaagtta
    77401 aaatagtgaa aacttaccaa gctcttgcaa atgcaaggct tttttggtat gatgaaatag
    77461 tcttcagggc agggtgaaat tcccgaccgg cagtgtaaaa cgtggtaatt tgttttacga
    77521 ctaggcagcg aatcgaagac catactgaat gtatgtcgag atgagctaac gcagttttag
    77581 aacaaaatag accgttggta gtctgcgagc gaaagctgat gtggtgcaat tccacaaccg
    77641 acagtaaagt ctggatggga gaagacgaag tggaggcctt ttgcctgctc ttccacgctt
    77701 cttcaatttt caaaattgga ggaaccttat gacaaacaca cgcaaaatga cgattatcgc
    77761 cattctctca gcagtatcct ttctgctcat gtatttgaaa tttccactga ttccaacagc
    77821 cagtttcctg gaagtggatt tttctctcgt accgatttta tttggtctgc ttattctaga
    77881 tatgaagtct agttttgcta tccttttggt acgaactttt ctcaaactga ttttaaataa
    77941 tcagggacca tcgacaatta ttggcttacc gatgaatatt gcagctatgt cagttttcat
    78001 tttagcagta gcttatttct ggaaaaatga acaaacgtta aaaaattatt taaaagcagc
    78061 cgctgttgcg acaattggtt cgacagcagt gatgctggca ttaaattacg tttatgcggt
    78121 gcctgtttat gctgcttttg caaattttga tattaaagaa atcttgggtc tgactaacta
    78181 tctttttatg atggtacttc cttttaatct tttacaaggg attgtgcttt cggcaatatt
    78241 ttatatctgt tacaaagcag cccaacctat tttaaagaaa gtttaacctt tataaggtaa
    78301 actatactgt atgaagaata aacaaatcca tttacgaaac gcatcttttt ttgctctggc
    78361 ctttgtgaca ttgggctatg tagtaaaatt ttatcctagt accctagcag gttttgattc
    78421 gactgtccag tctgccattc gtggaaattt accaagtgga gccagtcaat tttggacctc
    78481 tattactgtt ttaggaaata ctgttattat tttagctatt accatgattc tagctgctat
    78541 cttttactac tataaaaaat ggaagataga agcttatttc ctacttgcta gttttgcggc
    78601 gatgggtgtg gcatccacag ccctgaaata tgtctaccaa cgtccgcgtc caagtattga
    78661 atggttgatt gataccatcg gttattcatt tcctagctgg catactgcat caactatgat
    78721 gattggagga gcagttgtta ttattgttca ccagaggatg aagaaaggca tagctagact
    78781 tgtgctacaa gccatgttga ttctacttgc tgtcctggta gctgtatccc gtatctatat
    78841 tggggttcac tacccgacag atattatcgg tggttggcta cttgccgtca ctcttttaca
    78901 aatgatgtat ccattttacg atcagaaacg ctttgaatgg cgtttccaaa gtaagcaaaa
    78961 atagtcaatt tgacaccaac tcctactgta aaaggtagga gtttttttaa cttgtcatct
    79021 ttctattatc gttacttcgc ttttccgtcc tttgtagaag tggcttattt cacaagattt
    79081 attgagactg agctcaggca cagcgccatt tcttagagtt cgcactggac ttatcggaaa
    79141 atcgtgcaaa aatcctccga gaaattctca gaggatgatg atgtataaat ctagtttttg
    79201 attggaccat cagcaacggc ttcaacagca ttttttatcg tttgggcgaa gacttcgcct
    79261 ccattgcttt caagattgaa atgaacaagg tcggtattgt accaaattgg tggattatcc
    79321 tttgcaactt gataccagtc tgcaatggaa atataatcat atttttcagc caattctttc
    79381 tcgtattgac cagtttgata agaaatggat tcgctcggag tgaagtttcc atcgtaagga
    79441 gtgacaaaaa taaggcgacg tcctttagga aaatctttga ctagttggtc tagtagttcc
    79501 tgataattat ccgtagtatt tgtacctagc gctacaacta cagtctcttt caagctatta
    79561 ttttgcttat aaagatttat caatttagca atttcagaga gatttcgact gacagttcca
    79621 tcgatctgtg catctggtag cgcggtctgt atggcagaac tagcgcgaac agtaacagaa
    79681 tcgccaaaga tgataactcc tttttgaatt tcaaaactag tagctttagc gttttcagca
    79741 gcagatcgtg ttgtatttag ttgggtctga gcttgataaa gattgctaac catgctctct
    79801 tgttcaaaac ttcctaattt tggtccaaat agacagatac ctaagccaac tatggtcaag
    79861 caagcaaagc tgctaagaag ccatttttta tagggtttta agtctattgc taatccaaac
    79921 aagcttccta ctttaccagc aatatatggt tctagaatat agaaggaaat agttgatagg
    79981 atagtagaaa aaacaaagga taatcccgca gcgatagtgg catttgtcag ttgtgtaaag
    80041 ataatgagca agggccaatg gaagaggtag ataccataag aaatacttgc aaagaagagg
    80101 ataattgcag gttctttgac atcttcggtt ttctcgtgaa gtacccgagc agcaaaaatc
    80161 atagttgctg tagctaaact agatagaaga aaaccaatta gataggtcca gatggaactg
    80221 aattgaagag taaagagaag aagaagttct actcctagtc ctccaagaaa cagacctata
    80281 gcttgtttga tactcaatgt attcacttgt tgctggaagg cagttgttgt atttccgata
    80341 ccagcgatgg ttgcgagaat gcttccgagg aagaatggga aggtatgtgt gaagctcgag
    80401 tagtaaatgg ttgagaaatt atctacaaag aaacttgaga tagacattgc taaaaaactt
    80461 agcgagaaga ggcttataga tgttagaaaa attgatccac gtagttgccc cacacttttt
    80521 gagatgcgag tccgatacca aactaaacca gcccagacaa ggtaatactg aacttctatg
    80581 gctagtgtcc aagtatgcac aaatagatga ggtgaaaatt gattctcgta actaccacct
    80641 gatagaattt caaagaagtt tgtcatgaat ccgagcgcag cgactatctg attgccgata
    80701 ttggcaatga aatcattgcg gacaagcaga gcaagtggaa gaaccaaaag aatcgttaaa
    80761 accagagggg ggagaatccg atagaacctt cttctgaaaa agctgacaat atctattttt
    80821 ttatgttttg caaactcatc aatcaaaagg gcggttgtca aatatccaga cagggtaaag
    80881 aagaggtcaa cccccacaaa gccacctggg aaatatttga taaagaaatg atagagtagg
    80941 acaaagacta atccaatcac acgtataacg gataaccatt taattttcat attgataaat
    81001 cccctgttta aaagttcctt cgtaggtagc ttgtccttcg gtggtcaatt ttccttttcc
    81061 atcggcatag ccgtttttaa attgcccggt ataaacccac ccacttgcag atgtgtaggt
    81121 tccttgaccg tggaaaattc catttgtaaa ttgtccttcg tagacatctc cattatcaaa
    81181 ggtcaatttt ccttgaccat tcattttatt tgcgaccaca taaccgttgt actgcagggc
    81241 gccattattg aaagtcatgg cttgcttgct ggcaattcgc cctgtaaata cagagagggc
    81301 acagatgagg ataataataa gggagaggat ttcaagtttt ggacgggtga aatgacttgt
    81361 tatatcatgc cattttatac taggtaattt gaactctttc atcgttttac tctttcatag
    81421 gatttgaccg atgctaatca gttctttcta ggatacagta agaaattatc agttcagtca
    81481 gaaatagttt acca
//
LOCUS       DBNFCO010000002        68537 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.002, whole genome shotgun sequence.
ACCESSION   DBNFCO010000002 DBNFCO010000000
VERSION     DBNFCO010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 68537)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68537)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68537
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.002"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            <1..532
                     /locus_tag="AC1PIV_000085"
     CDS             <1..532
                     /locus_tag="AC1PIV_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HIP6611147.1"
                     /translation="DYSVTNIVRNSLIDEFDNFIEFLILNQVKAVRFGLFSHLGRGKL
                     VGSDWFLSPSKVEEFYEMLIEKSREYGSRINIHTWEEDNCFNYFEDIVDGTMRCGAGV
                     IEWTINESGHIKPCTFFPDGEFSSYSLQNFEEYSMQNHEQNIVRKINDWEGLLQTVGL
                     STRNICEEIYKMVEKK"
     gene            529..2106
                     /locus_tag="AC1PIV_000086"
     CDS             529..2106
                     /locus_tag="AC1PIV_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HIP6611148.1"
                     /translation="MKKRNFWLTLSCIFAVALLNVGFLYQYRYIIDAIAAGDRQAFVS
                     YFVQMGLTVLVMLVFEYIRQIANVSYLNQVGFQLQATFIGKIFDLPFRQFVEQGAGAY
                     ISQLNNDLETVKEDYYDAFFTIFQGACTFGIASLALLSLDGLTAIFLILISFLPVVIP
                     YLFKKRRRLNQEAISDSQQVYNTRVSDVFLSYLQVKNSHQRQQVLDGLNDRYQAVNDK
                     VNQATRTTVTMRLLVGFVFYLTTLSIIFIGGFQVFSGALTIGGLTAILTISEQLVDPI
                     NSIAAAFLDRHAVKKLKQEFELSTFGQETKGQELASAFQSIQLVKASYAVGEKQVFED
                     LTVAFERGKKYLILGESGSGKSSLALILTKNSQLQAGDIYVDQISLSDLSYQAIQDKI
                     AYLPQEGSLFHDTVLYNLTMGREVPEDRLMFHIKTVNLDSRFPSYASLSEEISDDSGL
                     SGGQKQRLLLIRALLQDKDILLLDESLSALDQETYAVIENYLASLADKTLIHISHRVS
                     DEVLSRYDGVVRIGESN"
     gene            complement(2526..2607)
                     /locus_tag="AC1PIV_000087"
     tRNA            complement(2526..2607)
                     /locus_tag="AC1PIV_000087"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2572..2574),aa:Leu,seq:cag)
     gene            3003..3878
                     /gene="rsgA"
                     /locus_tag="AC1PIV_000088"
     CDS             3003..3878
                     /gene="rsgA"
                     /locus_tag="AC1PIV_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HIP6611149.1"
                     /translation="MQGRIIKALAGFYYVEADGQIYQTRARGNFRKKGQTPYVGDFVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSAKEPDFNANLLDRFLVLLEQK
                     DMDPIIYISKMDLVEDRTEMDAFKAIYEKIGYPFVYSLEELMPLLQDKVTVFMGQTGV
                     GKSTLLNRIAPELALETGAISDSLGRGRHTTRAVSFYNVFGGKIADTPGFSSLDYEVK
                     EAEALTDCFPEIAESSQDCKFRTCTHTHEPDCAVKEAVASSAISQSRFDNYLQFLSEI
                     QNQRETYTKVSKKFK"
     gene            3893..4552
                     /gene="rpe"
                     /locus_tag="AC1PIV_000089"
     CDS             3893..4552
                     /gene="rpe"
                     /locus_tag="AC1PIV_000089"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HIP6611150.1"
                     /translation="MSHFKIAPSILAADYANFEKELKRLEKTGVEYVHIDVMDGHFVP
                     NISFGADVVAAMRPHSKLVFDCHLMVSNPENHIETFARAGADILTIHAEATVHLHGTL
                     QKIRAAGMKVGVVINPGTPLVTIEPVLNLVDQVLLMTVNPGFGGQAYIPEVADKIADL
                     VKLREAKGLAFDIEVDGGIDDKTIHSAKSAGANVFVAGSYLFKGDLDANVAKLRAALN
                     D"
     gene            4545..5177
                     /locus_tag="AC1PIV_000090"
     CDS             4545..5177
                     /locus_tag="AC1PIV_000090"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004788 - thiamine diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HIP6611151.1"
                     /translation="MIKIAVIAGGSFDCLPEPADLYVGVDAGSLRLLDHSLPLDWAIG
                     DFDSVTSEELGQIREMAEQFLQAPAEKDDTDLELALKEIFKAYPQAQVRIYGALGGRM
                     DHMMSNLFLVAEPDLAAYMEQIELVDSQNVVRFRPAGSHRISPIAGMKYISFMPSDQS
                     HLTIRYAKYPLDASNYFFKKCYASNEFIDRDIDIQLDQGYVVLIYSKDKD"
     gene            5178..6416
                     /locus_tag="AC1PIV_000091"
     CDS             5178..6416
                     /locus_tag="AC1PIV_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HIP6611152.1"
                     /translation="MDIVLLILLILVLLALVFLYGKWQSLALLLQDQAEDTADNLSDQ
                     LSYQLENATLKQQQTIHQEVERLRTELYQQLTDIRQELNKSHLETRDATDLRLQAIQE
                     SNEKRLEEMRQTVEEKLEKTLQTRLQASFEMVSKQLESVNRGLGEMQTVARDVGSLNK
                     VLSGTKTRGIMGELQLGQIIEDILTPSQYEREFATVSGSSERVEYAVKLPGRTEGDYI
                     YLPIDSKFPLADYYRLEDAYESGDKDQIDLHRKNLLAAIKRFAKDIQSKYLNPPETTN
                     FGVLFLPTEGLYSEVVRNPIFFDELRRQENIVVAGPTTLSALLNSLSVGFKTLNIQRS
                     ADDISKVLGNVKLEFGKFSDLLVKAQKQLNQASSNIDKLLTTRTNAIERSLRTIDLYE
                     DDQTKGLLGLSPLDEEDNEN"
     gene            6406..7347
                     /locus_tag="AC1PIV_000092"
     CDS             6406..7347
                     /locus_tag="AC1PIV_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HIP6611153.1"
                     /translation="MKINQMKKDEFFEGFYLIKSAEVRQTRAGKDYLALTFQDDTGEI
                     EGKIWDAQPGKIKDFTAGTVVHMQGCREVYNNTPQVNQLVLRLPKAGEPNDPADFKEK
                     PPVDVKDTKDYLSQMIFRIENATWQRIVRALYSKYDKEFYSYPAAKTNHHAFYSGLSF
                     HTATMVRLADKIGDIYPQLNKSLLFAGIMLHDLAKVIELTGPDNTGYTVRGNLIGHIS
                     LIDEEITKVLMELGIDDSLEEVTVLRHVILSHHGLLEYGSPVRPQIMEAEILHMIDNI
                     DAEMMMMLSALDKVGPGEMTNRIFAMDNRAFYKPNID"
     gene            7347..8213
                     /locus_tag="AC1PIV_000093"
     CDS             7347..8213
                     /locus_tag="AC1PIV_000093"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside phosphotransferase family
                     protein"
                     /protein_id="HIP6611154.1"
                     /translation="MAVRIVSRQPLTKGWSTDQKYKVQLEDGRLGLLRIAERPAYEAK
                     QLEFQLVENLFGLGLPVAEPLSFWADDLSVYTLYEWMEGQDMNDLATSLSEQTLYELG
                     CQSGKFLRTLHALPIDQSLRDWNSFYQAKIDNKLAAYQAASHSYPNGQAMIAFVQANR
                     HLLEGRPIAYHHGDFHTGNFLRGQDGRLKILDFDRYDIGDPWEEFNRLIFTADLSPAF
                     ARGQVDVYFDGAIPEEFWKLMALYVTVNSLGALSWAEQVDSEQIPLMKLQAQKISEWY
                     EYFNHHLPKWYM"
     gene            8315..9127
                     /gene="purR"
                     /locus_tag="AC1PIV_000094"
     CDS             8315..9127
                     /gene="purR"
                     /locus_tag="AC1PIV_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0045982 - negative regulation of purine
                     nucleobase metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HIP6611155.1"
                     /translation="MKLRRSERMVVISNYLINHPYELTSLNTFAEKYESAKSSISEDI
                     AIIKKAFEESSIGHIETITGASGGVVFTPSISKAESVEIAQALRDQMAESNRILPGGY
                     IYSSDLLSTPHILKNVGRIIADAFKDEKIDAVMTVATKGVPLANAVANVLNVPFVIVR
                     RDLKITEGSTVSVNYVSGSSDRIEKMFLSKRSLKAGSRVLIVDDFLKNGGTINGMISL
                     LSEFDSTLVGVAVFAENQKGDRSVANYKSLLAVTDINVKENRVDVELGNIFE"
     gene            complement(9154..10020)
                     /locus_tag="AC1PIV_000095"
     CDS             complement(9154..10020)
                     /locus_tag="AC1PIV_000095"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HIP6611156.1"
                     /translation="MKIDIRIPQAFPQLTVKEVLEDYFLIPRKIRHFLRTKKQVRVNG
                     ELINWQCPITAGDLLELTFDQEDYPEKSIPLGQADLVEELYQDEHLIIVNKPEGMKTH
                     GNDPTEIALLNHVSAYVGQTCYVVHRLDMETSGAILFAKNPFILPILNRLLEDKVIYR
                     DYLALCQGQLKMTDWTITDKIGRDRHDRRKRVVDNRKGQTALTQVRLLKTLGKNSLVS
                     CRLQTGRTHQIRVHLAHHGHALIGDPLYSRVAPPRLMLHAQKLSLTHPLTLEEISVEA
                     RSESFERIVKKS"
     gene            complement(10022..10990)
                     /locus_tag="AC1PIV_000096"
     CDS             complement(10022..10990)
                     /locus_tag="AC1PIV_000096"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HIP6611157.1"
                     /translation="MTQVYDITIIGGGPVGLFAAFYAHLRQAKVKIIDSLPQLGGQPA
                     ILYPEKAILDIPAFPSLTGQELTDNLLAQLAPFDTTICLNETLTAIEPGETITLTTNK
                     GNHQTKTLIIAMGGGAFKPRPLEIDGADSFDNVHYHVSNIQQYADKDIVVLGGGDSAV
                     DWSLAFEKIAKTTQIIHRRDNFRALEHSVEELKQSSVTIHTPFIPKGLSGENGRASAI
                     DFDKVKSEDKLTLSFDHLFVNYGFKSSVGTLKEWGLELNRHRIVVNSKQETSVPGIYA
                     IGDCCFYEGKIDLIATGLGEAPTAVNNAMNYLNPNEKVQPKHSTSL"
     gene            11143..13356
                     /gene="pbp2a"
                     /locus_tag="AC1PIV_000097"
     CDS             11143..13356
                     /gene="pbp2a"
                     /locus_tag="AC1PIV_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP2A"
                     /protein_id="HIP6611158.1"
                     /translation="MDDLQHQPIEVPEDFQIDHEDRPSRRHRGNRGSIDKPKKKSRIP
                     EPIRKFWRRYQLTKILIILMVLTVLTVGGYLFFLAKTANVGDLQQALKATTIIYDKDG
                     AEAGTLSGQKGTYVELDAISDNLENAVIATEDRSFYKNSGINYQRTILAALTLGRSGG
                     GSTITQQLAKNAFLTQDQTISRKAREFFLALEINKKYSKQEILTMYLNNAYFGNGVWG
                     VEDASQKYFGIPASNLTLEQAAVIAGMLKGPEIYNPYYSLENAVNRRDTVLQNMVNAG
                     YIDQATADAGFQVDLASQLSDTYTGKQSNYSYPSYFDAVIAEAIERYGLKESDIINNG
                     YRIYTEMDQNSQASMQVIFNDETMFPTSSFDGTHAQAASVALDPRTGGVRALVGRVNS
                     SEDAVFRTFNFATQAKRSPGSTIKPLVAYAPAVAAGWSIDMALDNHTETYGDYTLHNY
                     DYSTSDTIPMYQALALSYNLPVAYIVNTLGIDKAFEYGQKFGLDMENVEKVLGVSIGS
                     GVETNPLQMAQAYATFANKGVMKDAHLITRIETASGKVLAEHRETSTKVIDRAVADKM
                     TAMMLGTYTNGTGVTADTANYHIAGKTGTTETSFDVNLVNDQWHIAYTPDLVISQWVG
                     FEQTDENHYIDSSSYWKAPSVFQTVANSILPYTAGSKFEVENAYAQNGIVEVAPDEAA
                     QTESSLGQEQVQEISEQAKNLIEQTKQNLIDAQLPERAKTLWDNITSWFGELSNP"
     gene            13390..13542
                     /gene="rpmG"
                     /locus_tag="AC1PIV_000098"
     CDS             13390..13542
                     /gene="rpmG"
                     /locus_tag="AC1PIV_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HIP6611159.1"
                     /translation="MALKKASLACTVCGSRNYSISLSSNPKPTRLEVNKFCKHCGQYT
                     VHKETR"
     gene            13552..13728
                     /gene="secE"
                     /locus_tag="AC1PIV_000099"
     CDS             13552..13728
                     /gene="secE"
                     /locus_tag="AC1PIV_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HIP6611160.1"
                     /translation="MKFIKDIIRILKDTSWPTRKQSWTDFVSVVEYTAFFVAVVYLFD
                     LILSRGIMSLINLF"
     gene            13838..14377
                     /gene="nusG"
                     /locus_tag="AC1PIV_000100"
     CDS             13838..14377
                     /gene="nusG"
                     /locus_tag="AC1PIV_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HIP6611161.1"
                     /translation="MYDSFDKGWFVLQTYSGYENKVKENLLQRAHTYNMLENILRVEI
                     PTQTVQVEKNGEVKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKP
                     TPLLEEEIRQILVSMGQTVQEFDIDVKVGDTVRIIDGAFTDYTGKITEIDNNKVKMVI
                     SMFGNDTIAEVNLSQIAEL"
     gene            14521..19599
                     /locus_tag="AC1PIV_000101"
     CDS             14521..19599
                     /locus_tag="AC1PIV_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HIP6611162.1"
                     /translation="MKQKWSQIENKQRFSIKKLSVGVASVSIGFFITGVPMVQADTSG
                     EGLESTVAVATDMDSRQNSAVEKKEDGPLSDDPVKTEQVDEPVAEEGVVEEVVDTEAG
                     EESGLLTDQAATEIETTAGKTTDESKEKEDISGKEASAPQTIPQESQLEPEEVTTGRY
                     ILQFSEENRNLVLDKLKKIDGVKIVHEYKEVLTGASVEVGKESLSDVKAITELTSLEE
                     SRRIRPTLHTAKQLVGALKASSKYQTDGRGMVIAVIDSGLDIKHKDMRLDDGVIPKIK
                     DITPSTTGTYTLKVPHGYNYVSGNDNLYDDTHEPHGMHIAGTLAGNATDEEVASKKGV
                     DGIAPNAQLLVYKIFSNDPKNYKAETEDAAYAAIEDAIKHGADVISLSVGYYDSGLPG
                     NAYYTIAKRAAEKGIIITAAIGNAGASSSDTSFDLHTNNALGAVDTATTVGVAATPAV
                     IAVGSARNTHLVQREFMLNGQSFGYYPIGYTTLTEGKYEFVDAGNGHWEEVQGLDLAG
                     KVAVIKKDKFDLKDAVRNLKFKDVAGIIVINTDQGWNKDYYRTHQLLVDDKTLLSYSS
                     IWGISLSGEDGRRLLEVANQSQGNTGLVLKPTIGMKKLIEVPTVSGFSSWGPTVNLEL
                     KPEIVAPGEDVYATLNDNRYGSMSGTSMASPIVAGASALLLPRIRQMTPPEGMTRMDL
                     LRIILMNTATPLVDVLDSSGHALENSPRQQGAGLLQIDRAFETDVILHHRLKGGVELK
                     EIGRETEFEVTLENLGNQQRSFAISAGKVLTSQDVPVDRIGRSGKVVKEIHATEIKGS
                     SIHLSEQSIQLGPKEKRTIRLKLDAGEAKDQFAEGYIYFKSLTEGQSDISIPYFGFVG
                     DWSKERIVDAPAWETSSKLKLTSVLSSYKHNKSGRYIELGREKIQDNQSPLNPDNIAI
                     QNQHSDSQIGNAFVRFALLRDITNYDLDIVKEATEDAPVLRRIDTGTMLSRVRYVDYF
                     ESLSEYSKLRTPIELHRWDGKVYDASNDENIPAPEGQYFFRLRVKNKENGAYQYTYLP
                     VKIDNQKPEIVAIDTNRLSSHRELVVTAKDNNKVWEVRANLNGEDLLVEKVVDDAGQL
                     HYHLKEVELPLDAKNHLRVEVMDIAGNVVAVEKDLMAPVIQFKNLEDLMAIRSKKTVE
                     IKANVSAQVSDVQANLDAQAVNYSLENGQLSLQIPEQSDGRHSFELILKDKDGNLIYT
                     KTLNYLVDNEKPTIDLDIEKDEEDEEVIQIGKNGRFTLKGKVSDNVSLPKDIKLYYSN
                     LDIGKGERKIIDVKEDGSFEQDFFKSDFPRAIMLTAVDEKGNKLKDLRINTSPESLDE
                     EEETEVPITVNNWLIDPIRFNKESLGRELDSGLVDFKKQEDGTYLFTFEIEAETEQAH
                     SVRINGGEKRYFEDGKLTYPVTLIEEGNVVDISVYNEADELTYTKKYQMLVDTENPVL
                     QLENEVLPLERQVVDSEEDEDEENQYAGVLLADADGHLTLTGSAKDNGIYWSLKINED
                     FVARGGFWRQYGNNEKAFRYELHSLKDGDTVKLDLSDSFGNAVVKKYKVRLNDKEVSE
                     QVPEKDLHVERSDKDQTPSIPILKSEAHIPMPKEENSLAPQTGSTEIALLTGDTREDG
                     VEHLGKLTKHEEPLGISDERIEVSVPHREFFERSGIGETGALAADTSGKLPQTGDSLG
                     SVFISTLLGLFGGAMALGNLKRKE"
     gene            complement(19642..19712)
                     /locus_tag="AC1PIV_000102"
     tRNA            complement(19642..19712)
                     /locus_tag="AC1PIV_000102"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19678..19680),aa:Cys,seq:gca)
     gene            20253..20765
                     /locus_tag="AC1PIV_000103"
     CDS             20253..20765
                     /locus_tag="AC1PIV_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HIP6611163.1"
                     /translation="MIVLITGASHTGKTVLAQKLLEKYHYPYLSIDHLKMGLIRSGNT
                     KLSVEEDDKLTAYLWPIVREMIKTAIENEQNLIVEGIYIPFDWANDFATAYLDHIRYY
                     CLVMSENYIQKHFGSIKKHARLIENRIDDEWCTMESVLEENTRFFRRAKKYDANILWI
                     DESYEIEIDL"
     gene            21112..21888
                     /gene="rpsB"
                     /locus_tag="AC1PIV_000104"
     CDS             21112..21888
                     /gene="rpsB"
                     /locus_tag="AC1PIV_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HIP6611164.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKLADQAYEFIRDAAANDAVILFVGTKKQAAEAVKDEAIRAGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEINRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIADMPRIPDV
                     MFVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKMA
                     DAIIEGNQGEDSVAAVEAELAAEPASTESIEELVEVVEGK"
     gene            22044..23084
                     /gene="tsf"
                     /locus_tag="AC1PIV_000105"
     CDS             22044..23084
                     /gene="tsf"
                     /locus_tag="AC1PIV_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="HIP6611165.1"
                     /translation="MAEITAALVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVDGNVAAVVEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPADNEAALKLAMPSGETLEEAYVNATATIGEKISFRRFALVEKTDAQAFGAYQHNG
                     GRIGVISVVDGGDETLAKQISMHIAAMKPTVLSYTELDEQFVKDELAQINHKIEQDNE
                     SRAMVNKPVLPLLKYGSKAQLTDEVIAAAEEAIKAELAAEGKPEKIWDKIIPGKMDRF
                     LLDNTQVDQAYTLLAQVYIMDDSKTVEAYLNSVNASVVEFARFEVGEGIEKASNDFEA
                     EVAATMAAALGK"
     gene            complement(23347..24048)
                     /locus_tag="AC1PIV_000106"
     CDS             complement(23347..24048)
                     /locus_tag="AC1PIV_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HIP6611166.1"
                     /translation="MLDISYQANTFHISYQGRPLGKIHSNQNPYHQTNIYLRLDLVDF
                     DCKIAKQLFQSLQTSLGGKPLQVMLSSAEQERIHFLTTAGFVCKRKCYEFEVTKQDYL
                     SQTGTSNLSIVLKGTAPYQIVCQQIFDHYQTVHQDINPWTASQEEFEKGLPDLVYTDS
                     ENCAFIDTDEIAYVCGKDEQSFGSFIQAVICQLFEQYEQISFEADDCDPIAMHLADQF
                     RQPNKPSWDAYILEI"
     gene            complement(24048..24386)
                     /locus_tag="AC1PIV_000107"
     CDS             complement(24048..24386)
                     /locus_tag="AC1PIV_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin domain-containing protein"
                     /protein_id="HIP6611167.1"
                     /translation="MNFQDYIQDFTSVNVEQAQSLLTANEGAVLFIGRATCPYCNRFA
                     PKLHKVAQDKQVTIHFLDSSQVSPELQALRDHYQVPTVPGLLVAKSTGVQVRCDSSMT
                     EDEIAAFIQD"
     gene            24536..24994
                     /locus_tag="AC1PIV_000108"
     CDS             24536..24994
                     /locus_tag="AC1PIV_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HIP6611168.1"
                     /translation="MAMKNTSDYIEEHIKAILDQVSVAELRRSELASRFEVVPSQINY
                     VIKTRFTASRGYIVESKRGGGGYIRIGRITFSDKHELVHDLLKNMGDSLSATVFADIL
                     QLLFDEQLMTEREGNLLLATSTDEVLGNEASEIRARMMYQILRRLDRKEE"
     gene            25000..27453
                     /locus_tag="AC1PIV_000109"
     CDS             25000..27453
                     /locus_tag="AC1PIV_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HIP6611169.1"
                     /translation="MKISRGLQGVYEDAQLIAQRYSSDYLETWHLLLAFVINPDTVAG
                     AILAEYPADVLDYERAVYMVMGRRYHEELESFFFLPSSKRVKELQVFAEKIAEIVKSK
                     GLGTEHIFMGMLLDKRSTASQILDQVGFHFEDSDDKVRFLDLRKNLEAKAGFTKEHLK
                     AIRTMTKGGKPKQATVGNMMGMTQSQSGGLEDYTRDLTALARSGQLEPVIGRDEEISR
                     MLQILSRKTKNNPVLVGDAGVGKTALALGLAQRIANGEVPASLVNMRILELDLMNVIA
                     GTRFRGDFEERMNNIINDIEEDGRVILFIDELHTIMGSGSGIDSILDAANILKPALSR
                     GTLRTVGATTQDEYQKHIEKDAALVRRFAKVTIEEPSVADSVAILQGLKPAYEAHHKV
                     TISDQAVVTAVAYAKRYLTSKNLPDSAIDLLDEASATVQNRAKGQVEEGGLTALDQAL
                     MAGKYKTVTQLLLKAQEAENQATSYSLEVTEEDILATLSRLSGIPVTKLSQTDAKKYL
                     NLEQELHKRVIGQEEAISAVSRAIRRNQSGIRTGHRPIGSFMFLGPTGVGKTELAKAL
                     AEILFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLF
                     DEVEKAHPDIFNVLLQVLDDGVLTDRKGRKVDFSNTVIIMTSNLGATALRDDKTVGFG
                     ALDLSKSQEHVEKRIFEALKKAYRPEFINRIDEKVVFHSLTEADMQDVVKVMVKPLIA
                     VAASKGITLKLQASALKLLAKEGYDPEMGARPLRRLLQTKLEDPLAEMLLRGELPAGV
                     TLKVGVKAEQLKFDSVKAG"
     gene            27567..28604
                     /locus_tag="AC1PIV_000110"
     CDS             27567..28604
                     /locus_tag="AC1PIV_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HIP6611170.1"
                     /translation="MKQAVAVIFGTFAPMHKGHIDLIQRAKRECDRAVVIVSGYKNDR
                     GHQIGLGLQKRFRYIRETFNDEPLVSVFKLDEEGMPPYPEGWAPWLEALQALVAIKEN
                     EELVFYVSEQEYAEELRSRGFKASFTERNFGISATLIREQSAKYWNMIAKPFRRHFSK
                     NILVVGSASNGKTTLVRDLGRYYSCPVSLEYARYYQQRYNVRDDELTGKDYNYLLTGQ
                     YRQTSDLIDSDTNRGLVIADTNATVTEAYYDYYIGETSSSFHSLCADTVKNEKWDLII
                     FVLPTGSYVDDGFRDMTMADAEIRNAFTEHLKELVAKNHPQASLAFIGGSYAENYAKA
                     IELIDAIYQEF"
     gene            28614..29435
                     /gene="pnuC"
                     /locus_tag="AC1PIV_000111"
     CDS             28614..29435
                     /gene="pnuC"
                     /locus_tag="AC1PIV_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015663 - nicotinamide mononucleotide
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015890 - nicotinamide mononucleotide
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HIP6611171.1"
                     /translation="MEQLTKFIDRFQASLKQVPENMSAIANRAKKLGVIGVLDAIIAG
                     LFFGRTLGQWLYLLVLSSVPVILHVWSASEDWMGLFTSWTGIICVILVAEGRSSNYFF
                     GFISNLIYFVLSYQNMFYGEVMTAIFFIVMQPVGLYFWLSARVNGAAEEEKTEFEARK
                     LTLWGWVKWLVFAVLVWGSFGLIYKSIGSARPFRDSITDGTNWTGQFLQSYLYREQWI
                     FWIATNVFSIYLWWVGPDSGNLQMSVMYFVWTINSLVGWYQWSKSIKEGQVARNG"
     gene            29428..30201
                     /locus_tag="AC1PIV_000112"
     CDS             29428..30201
                     /locus_tag="AC1PIV_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HIP6611172.1"
                     /translation="MARPAGLSDKEYYEKYVTEAEFLDWYKKQDAPRFEKPSVTADMV
                     VYSFVEGRIKLLLIRRAAHPCQHKLSLVGGFIARGEDAYQTCQREIKKEAGLDLPRNH
                     IEQLLTVSDSERDPRGWMMTIAHLVYLPSQALDLVKPGPDGREPIVIDVDFKTSQCSY
                     EGQVLTAEDFAFDHYEIVMTSIQRIQGRMKWNPTFLNLLQQPFNIYAATDLVNLISPD
                     KKILHNNFLAKYGDFVEEVGVERLPKRKPRKTYRLKESS"
     gene            complement(30347..31351)
                     /gene="dusB"
                     /locus_tag="AC1PIV_000113"
     CDS             complement(30347..31351)
                     /gene="dusB"
                     /locus_tag="AC1PIV_000113"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HIP6611173.1"
                     /translation="MANLNTPFMIGDVEIPNRCVLAPMAGVTNSAFRTIAKEMGAGLV
                     VMEMISEKGLLYNNEKTLHMLHIDDNEYPMSIQLFGGDAEGLKRAADFIQKNTKANIV
                     DINMGCPVNKVIKNEAGAKWLKDPDKIYHIIKEVTSVLDIPLTVKMRTGWNNTDLAVE
                     NALAAESGGVAALAMHGRTREQMYTGTVDLETLTKVAGSLTKIPFIANGDIRNVEDAR
                     QRIEEVGADAVMVGRTAMGNPYIFNQINHYLETGEVLPDLSFDDKLNVAFDHLTRLTN
                     LKGESIAVREFRGLAPHYLRGSAGAAKIRGAVARAETIEQVQELFDQAREAYQERIAK
                     "
     gene            complement(31344..32210)
                     /gene="hslO"
                     /locus_tag="AC1PIV_000114"
     CDS             complement(31344..32210)
                     /gene="hslO"
                     /locus_tag="AC1PIV_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HIP6611174.1"
                     /translation="MDKIIKTLSKSGHFRAFVLDSTETVKTAQEKHDTMASSTVALGR
                     TLIANQILAVNEKGDTKITLKILASGAVGAIISVANTKGQVKGYIQNPDLDYKRTATG
                     EVIVGPLVGNGQFLVITDYGTGHPYNSMTPLISGEIGEDFAYFLTDSQQTPSAVGLNV
                     LLDEEDKVKVAGGFLLQVLPGATEVEIARFEKRIQEMPAISSLLASENHIEALLSAIY
                     GDDDFKRLSEEEIGFVCDCSKDRFLDALASLPKADLQEMKEEDKGVDITCQFCQTHYH
                     FDENDLEELING"
     gene            complement(32290..35409)
                     /locus_tag="AC1PIV_000115"
     CDS             complement(32290..35409)
                     /locus_tag="AC1PIV_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6359 domain-containing protein"
                     /protein_id="HIP6611175.1"
                     /translation="MKIRNRSLFYTVGSVAVTAGLLLSLATSPIPSVHATEVAIENYP
                     SLAITKSEVTIQGYLIAPLNSSGTAFDATNKTNLALGASMDTAAADTIPIQLKEPLRS
                     QFNLVNHPELVGKLVRITGTSDTYMKRAGIKPATAIEIVDSSSTNVQPPTSENTATKP
                     SDLVSTPIATVRSGAQGTEYTVSGKIISLVNGWGGNGFYLQGSDGAGIYIYPGAALGY
                     QLGDTVQLTGTLGEYKGELQLTTVSNHKAISENFNTPITETNIAQLATQAQATLVSLK
                     NLTVGDIQSDSYQNSTFTVTDSEGQTVDVRLDSRTGIKTADLLNRINKGDKINLTAIL
                     STYNGKIQLKPFDLSHFEVIEKATTEAGLGKTEAVTVGRIQGASHQSPLVNQSVMLKN
                     VVVTYVTSANNFYVQDVTPDGDTKTSDGINIFTDKLKTNVKVGDLVTIAGRVEEYQGR
                     GYAERDKTDLTITQIRATEVTVDGTAPVPSPIVLGLDRTIPADIIDNDGLAQFDPEQD
                     ALDFWESVEGMVVAVDDAKILGPLKNKEIYVTPATSQLPLNNVGGVNLRPEGNNTNII
                     PLLLKNGKQIVKSGDYFIGRIAGPVTYSYTNYKVYVDDSTLPTLHEGATKPETTTIIP
                     NDDKLTIASYNIENFSANSKSTSDAKVQRIAKSFVSDLHSPDVIGLIEVQDNNGATND
                     GTTDASKSAERLIAAIQAAGGPTYTYVDIAPENNKDGGQEGGNIRVGFLYNSKRVSLS
                     DKPIGTATQAVAWENGELNLSLGRIDPTNPAWAAVRKTLAAEFVFKGEKVVVLANHLN
                     SKRGDNGLYGKIQPVSFKSEEKRHILAQTIADFTKAGLAQNPNANIVMLGDFNDYEFT
                     KTIEILEAGGMANLVSRHDASDRFSYFYNGNNQSLDNMLVSTNLLERYAFDMVHVNSA
                     FMEEHGRASDHDPLLVQLDVTKAQEPTQPEPSDKQTDDSGTVNNSDDNGTTNNNKPTN
                     LSTSNQTAVNADDRSGATDKRQTTVTPTANNSQKKILPKTGGETSFVLITIGLVFLSA
                     CLVKKQKES"
     gene            complement(36295..38526)
                     /gene="gshAB"
                     /locus_tag="AC1PIV_000116"
     CDS             complement(36295..38526)
                     /gene="gshAB"
                     /locus_tag="AC1PIV_000116"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009910876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004357 - glutamate-cysteine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006750 - glutathione biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HIP6611176.1"
                     /translation="MLQKLSPNSPILQATFGIERESLRINSNHRVAQTPHPHKLGSRS
                     FHPYIQTDYSEPQLELITPIAQSTKEARRLLGAITDVAARSMDKQEYLWPLSMPPVIS
                     EEEIQIAQLDSDYEYQYRVGLGERYGKLVQSMSGIHYNFELGKDLTQQLFELSEETDF
                     IAFKNTLYLKLAQNFLNYRWLLTYLYGASSLAEKGFLTTEVGCVRSIRNSKYGYVNSD
                     DVHISFSSLQQYVADIEQAVQSGQLSAEKEFYSSVRLRGAKTSRDYLSKGISYLEFRS
                     FDLNPYDPLAISQETLDTVHLFILSLLWLDQLTDVDNTLAKADKLNNLIALSHPHTPL
                     PNDADATPILTAMKAIVLHFGLDDYYGQLIAHAEAALQDPRLTLSGKIAEQVEDGSLE
                     KFGQQQGQVFHDYAWTAPYALKGYENMELSTQMILFDAIQLGLNVEILDEEDQFLKLW
                     HGNHVEYIKNGNMTSKDNYVIPLAMANKVVTKKILDQAGFPVPAGAEFANKTDALRYY
                     GQVASSAIVIKPKSTNFGLGISIFQEPASLADYEKALDIAFSEDSHVLVEEFVAGTEY
                     RFFILDGKCEAVLLRVAANVVGDGSSTIRELVEQKNQDPLRGRDHRSPLEIINLGDIE
                     LLMLEQQGYTPDTVLPEGIQAFLRGNSNISTGGDSIDMTDQMDESYKQLAADMATAMG
                     AWACGVDLIIPDRTKPASKNKPNCTCIELNFNPAMYLHTYTYAGPGQSITPKILKKLF
                     PEL"
     gene            38891..40183
                     /locus_tag="AC1PIV_000117"
     CDS             38891..40183
                     /locus_tag="AC1PIV_000117"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HIP6611177.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGTKYKLHLIPSGIFFPEKISVIGNGVVVNPKSLVKEINYLHDSGVTTDNLRISDRA
                     HVILPYHIKLDQLQEESKGENKIGTTNKGIGPAYMDKAARVGIRIADLLDKEIFAERL
                     RTNLAEKNRLFEKMYESTPIEFDEIFEEYYAYGQEIKKYVTDTSVILNDALDQGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELHDEIGDRIREIGKEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLGTLKICVAYDLDGERIDHYPASLEQLKRCKPIYEEMPGWSEDITGVRSLDELPEA
                     ARNYVRRISELVGVRISTFSVGPGREQTNILESVWSAK"
     gene            40293..40616
                     /gene="yajC"
                     /locus_tag="AC1PIV_000118"
     CDS             40293..40616
                     /gene="yajC"
                     /locus_tag="AC1PIV_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HIP6611178.1"
                     /translation="MEGLFLPLVMVAMIGFMFYSQRKQQKQRQEALNQIKKGDEIVTI
                     GGLFGIVDEIDDKKVVLDVDGVYLTFERGAIRDRVASSDATSAVVEEVAVETPEATPE
                     SAIEE"
     gene            40730..41485
                     /locus_tag="AC1PIV_000119"
     CDS             40730..41485
                     /locus_tag="AC1PIV_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HIP6611179.1"
                     /translation="MFKFNFKKKESIETAIEVPKHIAVIMDGNGRWAKKRMQPRIMGH
                     KAGMDALQKVTKTASDLGVKVLTVYAFSTENWSRPEKEVKFIMNLPVEFYDKYVPELH
                     ANNVKIQMIGDHSKLPVPTLNALYKAEQKTKGNTGLILNFALNYGGRDEVTRAVKAIA
                     QDVLDAKFNPGDIDEKLIADYLYTGTLSPTLRDPDLVIRTSGELRLSNFLPWQTAYSE
                     LYFTDIAWPDFDGEALKLAIKEYNRRHRRFGGV"
     gene            41495..42301
                     /locus_tag="AC1PIV_000120"
     CDS             41495..42301
                     /locus_tag="AC1PIV_000120"
                     /EC_number="2.7.7.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004605 - phosphatidate
                     cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0016024 - CDP-diacylglycerol biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HIP6611180.1"
                     /translation="MTNDLQKRVIFGGIALAIFIPFLLAGGMAFQFFVGLLAIIATAE
                     LIKMYRLAPNSIEGVLAMLASLVLALPLQNYLTFLPTDGNYTAYAIVVFLLLGSTVFN
                     IGHYNYSDVVFPIASSFYVGIGFHSLILARMDGLNKVFFALCLVWATDIGAYLIGRQI
                     GRRKLLPKVSPNKTVEGFVGGILSAVVVAIIFLIVDKSLLAGYSFGMMLLLVVIFSIF
                     SQFGDLVESAIKRHFGVKDSGKIIPGHGGILDRFDGMIFVFPIMHFFGLF"
     gene            42311..43570
                     /locus_tag="AC1PIV_000121"
     CDS             42311..43570
                     /locus_tag="AC1PIV_000121"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M50 family metallopeptidase"
                     /protein_id="HIP6611181.1"
                     /translation="MKGILAFIFIFGVIVVVHEFGHFYFAKKAGILVREFAIGMGPKI
                     FAHTGKDGTLYTIRILPLGGYVRMAGWGEDKTEIKTGSPASLSLNEAGVVTRINLSGK
                     QLDSLSLPMNVTSFDFEEKLEITGLVLEESKTYKVDHDATIVEEDGTEVRIAPLDVQY
                     QNATVWGRLMTNFAGPMNNFILGILVFILLFFMQGGVANPSSNAVSITEGGALQAAGV
                     VTGDKILSVNGNTTDSYTEVATIISKAATDATTAPSFDLVVEHDGKNRHVSVTAEQVD
                     GAYRIGISPILKTGFVDKIVGGFQEAGATALRVVTALKNLIANFDVKQLGGPVAIYKV
                     SSQAAEFGLVSVLGLMAALSINLGIFNLIPIPALDGGKIVMNILEAIRRKPLKPETES
                     YITLAGVAVMVVLMIVVTWNDIIRVFF"
     gene            43851..45713
                     /locus_tag="AC1PIV_000122"
     CDS             43851..45713
                     /locus_tag="AC1PIV_000122"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009910872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0002161 - aminoacyl-tRNA deacylase
                     activity [Evidence IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HIP6611182.1"
                     /translation="MKQSKMIIPTLREMPSDASVISHALMLRAGYVRQISAGIYSYLP
                     LANRVIEKAKNIMREEFDKIDAIEFLAPALLSADIWRESGRYETYGDDLYKLKNREGS
                     DFILGPTHEETVTLLARDAVQSYKQLPLNIYQIQPKYRDEKRPRNGLLRGREFIMKDG
                     YSFHASYESLDQTYDDYKAAYEAIFTRAGLEFKAIIGDGGAMGGKDSQEFMAITPDRT
                     DLDRWVVLDKSVASFEEIPEDVLEAFKAELLAWSVSGEDTIAYSSESGYAANLEMATS
                     EYKPSTAVVVEEDLVKVATPDAKTIDEVAAFLNVAEEQTIKTMLFMADGEPVVALLVG
                     NDQVNDVKLKNHLAADFFDVASPADAEKVFGAGFGSLGPVGLPENIKIIADRKVQDVK
                     NAVVGANEDGFHYTGANAGRDFQVTEYVDIREVKEGEPSPDGHGVLNFARGIEIGHIF
                     KLGTRYSDSMNANILDENGRSMPIIMGCYGIGVSRLLSAVLEQHARLFVNKTPKGEYR
                     YAWGINFPKELAPFDVHLIPVNVKDEAAMELTQSIEASLVGAGYEVLTDDRNERVGVK
                     FSDSDLIGLPIRVTVGKKAADGIVEVKIKGTGDTVEVHVDQLLETLQILTKENE"
     gene            complement(45895..46605)
                     /locus_tag="AC1PIV_000123"
     CDS             complement(45895..46605)
                     /locus_tag="AC1PIV_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HIP6611183.1"
                     /translation="MNLIGELLGTFILVLLGNGVVASCILSKTKAENSGWLTIVLGWG
                     IAVTIAVYISGIFGPAHLNPAVTIAMASIGSLPWAQVPGFLLAQFAGAMLASIVLYLH
                     FYPHWQETKDSGTILATFSTAPALRHTASNLLGEALGTAVLVMGILAIGPNNVSAGLG
                     PIIVGLIVFAIGFSLGSTTGYAVNPARDLGPRIMHAILPIPNKGDSDWSYSWIPVAGP
                     ILGGVAGAILYNILLNML"
     gene            complement(46615..46989)
                     /gene="dhaM"
                     /locus_tag="AC1PIV_000124"
     CDS             complement(46615..46989)
                     /gene="dhaM"
                     /locus_tag="AC1PIV_000124"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase phosphoryl donor subunit
                     DhaM"
                     /protein_id="HIP6611184.1"
                     /translation="MTKVGILLVSHSKNLAQGIIDLVSEVAKDIPITYCGGLEDGSIG
                     TSFEIVQERVEANPADTLLAFFDLGSARMNMELAADFTDKQILIQTVPVVEGCYTAAA
                     LLQAGADLETILEQLKELTINK"
     gene            complement(46986..47561)
                     /gene="dhaL"
                     /locus_tag="AC1PIV_000125"
     CDS             complement(46986..47561)
                     /gene="dhaL"
                     /locus_tag="AC1PIV_000125"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaL"
                     /protein_id="HIP6611185.1"
                     /translation="MDAKQALLWMETFNKKIQENKDYLSELDSPIGDGDHGGNMARGM
                     AAVMQELSEKDYETADQVFKVVAMQLLSKVGGASGPLYGSAFMGITKASQAGADLADT
                     LQAGLDMIQKRGKAELGEKTMVDVWIPVISALRESQLTTEIIHKAVQGTKDIAATKGR
                     ASYVGERSIGHIDPGSFSSGLLFEAMLEAGL"
     gene            complement(47572..48561)
                     /gene="dhaK"
                     /locus_tag="AC1PIV_000126"
     CDS             complement(47572..48561)
                     /gene="dhaK"
                     /locus_tag="AC1PIV_000126"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004371 - glycerone kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HIP6611186.1"
                     /translation="MKKIINQPEHVVDEMLKGLVFMHQDLVDRIDGFDVIIRKAEKTG
                     KVGIISGGGSGHEPSHAGFVGKGMLSAAVCGAVFTSPTPDQILEAIKAADEGAGVFMV
                     IKNYSGDIMNFEMAQELAEMEGIEVASVIVDDDIAVENSLYTQGRRGVAGTILVHKIL
                     GHAATTGKSLAEIKELADRLVPQIKTIGLALSGATVPEVGKPGFVLEEDEFEYGVGIH
                     GEPGYKKEKLQPSAKLAEELVEKLAEGFDIQDGEHYGVLINGLGATPLMEQYVFANDV
                     AQLLAKKGVVVDYKKIGNYMTSIDMAGLSLTLIKLEDPSWIDALQAPVEVVAW"
     gene            48714..49259
                     /gene="dhaS"
                     /locus_tag="AC1PIV_000127"
     CDS             48714..49259
                     /gene="dhaS"
                     /locus_tag="AC1PIV_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009910868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase transcriptional
                     activator DhaS"
                     /protein_id="HIP6611187.1"
                     /translation="MPTSLITKKRIAKAFKKQLSQKSFDKISVVDIMQEAGIRRQTFY
                     NHFLDKYELLDWIFETELQEQVTDNLTYISGIKLLDELLYYIESNQSFYRQLFEIKGQ
                     NDFVSYLEGYFMVLMEKIINEYQLQEGKMISQQDKHFLILYHANAWIGLIKEGLTQSP
                     CQIHSYWKQMVALVRESFVIL"
     gene            49270..50259
                     /gene="dhaQ"
                     /locus_tag="AC1PIV_000128"
     CDS             49270..50259
                     /gene="dhaQ"
                     /locus_tag="AC1PIV_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004371 - glycerone kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DhaKLM operon coactivator DhaQ"
                     /protein_id="HIP6611188.1"
                     /translation="MVFIRNRQATIIEDYLDGFCRTNPKVKKVKGLPIVLQKVQDDHL
                     VPIISGGGSGHEPAHIGFVGKGMLTAAVYGEIFTPPTAEEVFAAIRAVDKGKGVFLIV
                     KNFEADLISFRKAIELARQEGIAVKYIVSHDDISVDTKNNFRMRHRGLAGTILLHKIL
                     GAAALTGYSLDELEQLGLSLATEIATIGFATKSAYLPNAALPLFDLEEGQISYGIGIH
                     GEEGYRTVRFESSEQLANEIVNKLKLKFRWKEGEDYILLVNNLGSMSEVEQGIFLNDI
                     CQFLELEGLQLSYVKTGKFMTSLDMGGISVTLCRVKDRKWLDFLEAPTEAAAW"
     gene            50384..54775
                     /locus_tag="AC1PIV_000129"
     CDS             50384..54775
                     /locus_tag="AC1PIV_000129"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002907973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HIP6611189.1"
                     /translation="MSDKFQLLLQQIGMPLDARQSGAFSTATIEKVVLHKVSKLWEFT
                     FRFETPLPLMDYQLFKARLATEFEKVGNKIQFSIVSDAEAFEAGLVEAYYPEAFTEDL
                     CQSAGFKALFQPLEVAYRDGVLWIKGPETIDTDHFRKNHLPNLVEQYKRFGFGNLAVD
                     IQVCQEMTQQQAEIFHAQNAEIYQQANEENLAALEQLAQMAPPPEAAQPFVPEYKKNR
                     PAKVNIEKAEITPMIEVDSEENRIVFEGLVFEVEQKTTKTGRVIINFKMTDYTSSFTL
                     QKWAKNEEEAQKFDMVKKGNWLRVRGNVETNNFTRDLTMNVQEVQEVKKEIRKDLMPE
                     GEKRVEFHAHTNMSTMDALPAVEDLVARAAAWGHKAVAITDHGNVQSFPHGYHAARKA
                     GIKPLFGMEANIVEDSVPIAYNEADVVLSDATYVVFDVETTGLSAVNNALIQIAASKM
                     HKGNIIAEFDEFIDPGHPLSQFTTDLTGITDEHVRGSKPLEQVLREFQDFCQDSVMVA
                     HNATFDVGFMNVNYERAGLPIISQPVIDTLEFARNLYPDFKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFLKDALEKHNLTNLNQLNTELIAEDSYKKARVKHATLYVIN
                     QVGLKNMFKLVSLSNTKYFEGVPRIPRTVLNAHREGLILGTACQEGEVFDDLLSKGID
                     EAVKTAAYYDFIEVMPPALYAPMIAKEQFKDMAEIEETIKQLIEVGRRAGLPVLATGN
                     VHYIDPEEEIYREIIVRALGQGAPINWTIGNGENAQPAPLPKAHFRTTSEMLDEFAFL
                     GESLAREIVITNPNAMLDRFEDVQVVKTDLYTPYIEKAEETVAELTYQKAFEIYGNPL
                     PDIIDLRIEKELTSILGNGFAVIYLASQMLVHRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPMPPHYVCPNCQHSEFITDGSYGSGFDLPDKDCEKCGTKYKKDGQDIPFETFLG
                     FDGDKVPDIDLNFSGDDQPSAHLDVRDIFGEENAFRAGTVGTVAAKTAYGFVRGYERD
                     YGKFYRDVEVERLAAGAAGVKRTTGQHPGGIIVFPDYMDVYDFTPVQYPADDVTASWQ
                     TTHFNFHDIDENVLKLDILGHDDPTMVRKLQDLSGIDPQTIPADDKGVMALFSGTEIL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVEETKPTTFSELLQLSGLSHGTDVWLGNAQD
                     LIKAGIANLSTVIGCRDDIMVYLMHAGLPPKMAFNIMERVRKGLWLKISEEERNGYIQ
                     AMKDNKVPDWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPLYYYCAYFSIRAK
                     AFDLATMSGGLERVKAKMEEIALKKKNNEASNVEQDLYTTLELVNEMLERGFKFGKLD
                     LYKSHATDFLIEEDTLIPPFVAMDGLGENVAKQVVAARAEGEFLSKTELRKRGGLSGT
                     LVEKMDEMGILGKMPEDNQLSLFDDLF"
     gene            54787..55458
                     /locus_tag="AC1PIV_000130"
     CDS             54787..55458
                     /locus_tag="AC1PIV_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HIP6611190.1"
                     /translation="MKKRNILVELLKGIGLVLLSTILWTLILSFATPESSSGIYEPFP
                     GFTVIAGILTSFILHIIMKYNQLRQAEQAAKASKSHIVVIEERNQALMKKANRLVEKH
                     QNLEKETILDINKSVSKIRTVEEKTVMKSTKIESSQEFGQFLRQMPELMANKHIERLL
                     NEIFETENNLAQWKISYNQQVEYFNTLLHQFPISVIAKIIRLKDLEFYKEHSLTDFTD
                     EMLGL"
     gene            55694..56296
                     /locus_tag="AC1PIV_000131"
     CDS             55694..56296
                     /locus_tag="AC1PIV_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012997947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HIP6611191.1"
                     /translation="MSNFAKLQETRRSIYALGKDLPVSNEEVVALVEKAMKESPSAFN
                     SQSSRAVVLFGAESEVFWNEIAYSELEKVTPAEAFEATKGRLAGFAAGAGTILFFEDQ
                     DVVKGLQESFPLYAENFPIWFEQAHGINLYAVWLAFAEKNIGMNVQHYNPLVDAQVAE
                     KYGIPANWKLRAQAPFGSIAAPAADKDYMADSDRVKVFGN"
     gene            56569..57810
                     /locus_tag="AC1PIV_000132"
     CDS             56569..57810
                     /locus_tag="AC1PIV_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HIP6611192.1"
                     /translation="MVLPNFKENLAKYAKLLVSTGINVQPGHTVQLTIGVEQAELARL
                     IVKEAYAHGAKEVLVNWLDDVIARERLVNVDVELLEQVHPQRITEMNYLLERKASRLV
                     VLSEDPGAYDGVDPEKLSRNARALSQALNPMRQASQANKISWTLGAASGLEWAKKVFP
                     NATSDEEAVDLLWDQIFKTCRIYDEDPIKAWEEHEARLVAKAKVLNDEQFVKLHYTAP
                     GTDLVLGMPKNHLWEAAGSINAQGEKFIANMPTEEVFTAPDYRVADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGEIVDVTAEKGDEVMKKLVFDNAGARGLGEVALVPDKSPISQSGV
                     TFFNTLFDENASNHLAIGQAYAFSIEGGTEMSQEELKEAGLNRSDVHVDFMIGSNKMN
                     IDGIREDGTRVPIFRDGEWAI"
     gene            57869..58102
                     /locus_tag="AC1PIV_000133"
     CDS             57869..58102
                     /locus_tag="AC1PIV_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HIP6611193.1"
                     /translation="MLSSIIAGAIIGLIAGALTSSDDRRGCLGNIILGLAGSWIGQLL
                     FGDWGLQFAGMAVVPSVLGAILLVAIFSSSRRN"
     gene            58482..60044
                     /locus_tag="AC1PIV_000134"
     CDS             58482..60044
                     /locus_tag="AC1PIV_000134"
                     /EC_number="2.3.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009910861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003852 - 2-isopropylmalate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HIP6611194.1"
                     /translation="MRVIEFLDTTLRDGEQTPGVNFSIKEKVTIAKQLEKWGISAIEA
                     GFPAASPDSFEAVRQIAAAMTKTAVTGLARSVKSDIDACYEALKDAKYPQIHVFIATS
                     PIHREFKLQKTKEEILAQITEHVSYARERFEVVEFSPEDATRTELDYLLEVVQTAVDA
                     GATYINIPDTVGFTTPQHYGEIFRYLTTNVKSDREIIFSPHCHNDLGMAVANTLSAIK
                     NGAGRVEGTINGIGERAGNAALEEVAVALEIRKDFYDVTSPIVLKETLNTSELVSRFS
                     GIAIPRNKAVVGGNAFSHESGIHQDGVLKNPSTYEIITPELVGVKKNSLPLGKLSGRH
                     AFVEKLKELDLYFEEGDVASLFARFKNLADKKEKITDADIRALVAGTEISNRDGFQFK
                     DLRLDSQSDGSIQAQVIFINQDEEEVVVSESGKGSVEAVFNAIDQFFHQEISLERYHI
                     DAITDGIDAQARVLVAVENKATETVFNASGIDFDVVKASAIAYIHANVMVQKENSGQI
                     DKKLSEKELPHI"
     gene            60053..61099
                     /gene="leuB"
                     /locus_tag="AC1PIV_000135"
     CDS             60053..61099
                     /gene="leuB"
                     /locus_tag="AC1PIV_000135"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003862 - 3-isopropylmalate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HIP6611195.1"
                     /translation="MTKKIVALAGDGIGPEIMEAGLAVLEAVAGQVGFDYEIEERAFG
                     GAGIDASGHPLPKETLQACRKADAILLAAIGSPQYDDAAVRPEQGLLQLRKELGLFAN
                     IRPVKIFDSLKDYSPLKVDRLDGVDLVMVRELTGGIYFGEHILGTDQASDSNTYQAEE
                     IERVVRSAFDLAQKRRKKVTSIDKQNVLATSKLWRKVADEVAKDYPDVVLEHQLVDSA
                     AMLLITNPSRFDVLVTENLFGDILSDEASVLTGTLGVLPSASHAVAGPSLYEPIHGSA
                     PDIAGQGIANPVSMILSVAMMLEESFDLVQAGQTIRQAVEAVFAEGIFTKDLGGSAST
                     KEMTAAIIAQIGGG"
     gene            61102..62421
                     /gene="leuC"
                     /locus_tag="AC1PIV_000136"
     CDS             61102..62421
                     /gene="leuC"
                     /locus_tag="AC1PIV_000136"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="HIP6611196.1"
                     /translation="MSGKSIFDKLWDRHVITGQEGQPQLLYVDQHYIHEVTSPQAFQG
                     LRDTGRSVRRPDLTFATFDHNVPTVDIHNIRDVISKAQMDALAKNIEDFGIPHAAHGS
                     EHQGIVHMVGPETGRTQPGKFIVCGDSHTATHGAFGAIAFGIGTSEVEHVLATQTIWQ
                     VKPKRLLVEFVGQAQRGVYAKDFILALIARYGVDCGLGHVVEFAGPVIDRLSMEERMT
                     ICNMSIEFGSKMGIMAPDQTTFDYLRGRECAPADFDAAVADWKELYSDADTVYDKHLV
                     LDVSDLAPMVTWGTTPAMGVSFDETFPSIRDHNDERVYAYMDLAPGQKAADIPVGYVF
                     LGSCTNARLSDLQLAARIVKGRKIAEQVTAIVVPGSRPVKRAAEKLGLDKVPAGVHCA
                     STSNRNFEDRQGFGAKTHLCSPAMAATAALYGRFVDTRQLDILKAGV"
     gene            62421..63014
                     /gene="leuD"
                     /locus_tag="AC1PIV_000137"
     CDS             62421..63014
                     /gene="leuD"
                     /locus_tag="AC1PIV_000137"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA];
                     GO_function: GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HIP6611197.1"
                     /translation="MHQFTTWTGTTVPLMNDNIDTDQLLPKQFLKLIDKKGFGKYLLY
                     AWRYLDDNYTDNPDFILNQPEYQGASILISGDNFGAGSSREHAAWALADYGFKVIIAG
                     SFGDIHYNNDLNNGILPIIQPKEVRDQLAQLGPDQEITVDLADQLIRTPFGECPFDIE
                     QDWKHKLLNGLDDIGITLQYQDLIAEYEDNRPSYWQN"
     gene            63074..63859
                     /locus_tag="AC1PIV_000138"
     CDS             63074..63859
                     /locus_tag="AC1PIV_000138"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HIP6611198.1"
                     /translation="MTKQIHWDGGLSQEGFDIIKGEGGVIVCPTKVGYIIMTADKAGL
                     ERKFDAKERKRNKPGVVLCGSMEELRELAQLTPEIDAFYQKHWDEDILLGCILPWKPE
                     AYAKLQAYGDGREELMTDVRGTSCFVIKFGVAGEQIAKEMWEKEGRMVYASSANPSGK
                     GNRGKVEGIGERIASKVDLIIEADDYVTSIQPDKTIETRYEQGVMVSMVDKDGKLIPE
                     QSADSRSISPCPVVIRKGLDIDKIMMHLSDHFNSWDYRQGEYY"
     gene            complement(64048..64662)
                     /gene="def"
                     /locus_tag="AC1PIV_000139"
     CDS             complement(64048..64662)
                     /gene="def"
                     /locus_tag="AC1PIV_000139"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HIP6611199.1"
                     /translation="MSVIERLTKAAHLIDMDDIIREGHPTLRQVAEEVAFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMKLRGGVGLAAPQIDVSKRIIAVLVPNPEDEEGNPPAQ
                     AYSLQEVLYNPKIVAHSVQEAAMEGGEGCLSVDREVQGYVVRHARVTVDYMDKNGEKH
                     RIKLKGFNAIVVQHEIDHLNGVMFYDRIDPEHPFAVKEGMLVIE"
     gene            64792..65961
                     /locus_tag="AC1PIV_000140"
     CDS             64792..65961
                     /locus_tag="AC1PIV_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HIP6611200.1"
                     /translation="MKRILEKASLLALSTMLVSTFAVSPAIPQMIEYFAQQGIAAAQV
                     ENLITVTSFAIMVTLLANGLVVRFLSERNIIIAGLLLMAIGGALPMFLTAYPLILLAR
                     ILLGLGIGLINARAINIIGNFFTGQERVQMMGLRGSAEVLGSAGLTLLVGWLTQFGWQ
                     PAFLVYLFALVILALFLIFVPKEELLSRMEVKVEENAPKVKLDKTMWMMGIYLAFLAF
                     FVINVNTFLTIRIPQIVLAKGIGTAQQASLILSLMQVMGIVAGTVFSSLVGRLKGWLL
                     AVSYVVFGLAVVGIAFADNLWVLGLGGMVSGFFYSIILTIVFSQVTDRAPKALLNAVM
                     TIVLMGCNIGGATSAILPTYLEKLNPTPTGAFGIYAIGCALISAGLIYKQLKKWE"
     gene            66258..66431
                     /locus_tag="AC1PIV_000141"
     CDS             66258..66431
                     /locus_tag="AC1PIV_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HIP6611201.1"
                     /translation="MLENNRLNELILRFPEDVQLIFKDMIPSYQLGYVDYVYQTDSYA
                     TQNRRIKNLAKNF"
     gene            66435..66884
                     /locus_tag="AC1PIV_000142"
     CDS             66435..66884
                     /locus_tag="AC1PIV_000142"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIP6611202.1"
                     /translation="MDYFYIMPLPQDLALEIANQWRYQPPLDAYTISANPEIYAVMIS
                     PEARGDRFFAVIRNAALMGYFCIDQDGETVDIRLGMKPSLTGQGNGRAFYQAIEDYLV
                     EHVQPASIKLTVASSHQVAQKLFHALGFTEIEKQAEYIKMEKKLVCD"
     gene            66875..67603
                     /locus_tag="AC1PIV_000143"
     CDS             66875..67603
                     /locus_tag="AC1PIV_000143"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_function: GO:0140098 - catalytic activity, acting on
                     RNA [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HIP6611203.1"
                     /translation="MRLDKFLVDCGVGSRTEVKKLLKNKQVTVNGQVETSPKQQINEK
                     KDQIAVAGQVLSHETFVYYLLNKPKGVISATEDDHHRTVLDLLDNTARQKEVFPVGRL
                     DIDTHGLLLLTNKGQLAHAMLSPKKHVDKLYRAQVDGIMTQEDVERFAAGIELKDFTC
                     QPAQLTILSTDEAKQTSLVDITIREGKFHQIKRMVQACGKTVTDLQRLTMGPLRLDPK
                     LALGEYRRLTAAELKQLEVFGVEL"
     gene            68005..68514
                     /locus_tag="AC1PIV_000144"
     CDS             68005..68514
                     /locus_tag="AC1PIV_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611204.1"
                     /translation="MLKYIRALPLVIVAGAVVYFTIFICIDNGDWTYVVTRALGLKEE
                     HANNVSLIVIGAQSLFLTSDWFYKRIRAFLNRRLEKAKGLNRQIYLGYKAGIEFLMAL
                     PKRTILFTFYLLLVVAESVGLIEKAKDYAAVIIFIIAVDRVTKIWPEEKGRMIEFSQK
                     IKKRIKSVE"
BASE COUNT        18923 a        13687 c        16823 g        19104 t
ORIGIN      
        1 agactattca gtgaccaata ttgttcgaaa cagtcttatc gacgaatttg ataattttat
       61 agaattttta atactaaacc aagtaaaagc ggtgagattt gggctattta gtcatttggg
      121 tagaggtaag ttagtcggat cagattggtt tttaagtccc tctaaagtag aagaatttta
      181 tgagatgctt atagaaaaaa gtagagagta tgggagcaga attaatatac atacatggga
      241 agaagataat tgctttaact attttgaaga cattgtagat gggacaatgc gttgcggagc
      301 aggtgttatt gaatggacaa tcaatgagag tggccatatt aagccgtgta cattctttcc
      361 ggatggtgag ttttcttctt actctcttca aaattttgaa gaatattcaa tgcaaaatca
      421 cgaacagaat attgtaagga aaataaatga ttgggaaggt ttgctccaga cggttgggtt
      481 atcaactaga aatatttgcg aagaaatcta taaaatggtg gagaagaaat gaaaaagagg
      541 aatttttggc taaccttatc ttgtattttt gcagtagccc tgctaaatgt tggctttctg
      601 taccaatatc gctatattat tgatgctatt gcagctggag atagacaggc ctttgtgtct
      661 tattttgtgc agatggggtt aactgtcctt gtcatgctgg tttttgaata cattcgtcag
      721 attgccaatg tcagctatct caatcaagta ggtttccaat tgcaggcgac ctttattggg
      781 aaaatttttg atttaccttt taggcagttt gttgagcagg gggcaggggc ctatatttct
      841 cagctcaata atgatttgga gacggtgaaa gaagattatt acgacgcttt ctttacaatt
      901 tttcaaggtg cttgtacctt tggcattgcc agtttggccc ttcttagctt ggatggtctg
      961 accgctattt tcttgattct gatctcattc ttaccagttg tgattcccta tttgtttaaa
     1021 aagcggagaa ggctcaatca ggaggcgatt tcggacagtc agcaggtcta taatacaaga
     1081 gtttcagatg tctttctgag ttatttgcaa gtgaaaaata gccaccaaag acagcaagtt
     1141 ttagatggtc tgaacgatcg ctatcaagca gtcaatgaca aggtcaatca ggccactcga
     1201 acgacagtaa ccatgcggct cttagtcggt tttgtctttt atctgaccac tctttcgatt
     1261 atctttatcg gtggttttca agtcttttct ggtgccttga ccatcggtgg cttgacagct
     1321 attctgacca tttcagagca gttggtggat cccattaata gcattgcggc agcctttttg
     1381 gacaggcatg ccgttaagaa attaaagcaa gagtttgagc tatctacttt tggtcaagaa
     1441 acgaagggac aggaactagc ttcagctttc cagagtattc aactggtcaa ggctagttat
     1501 gctgtcggtg aaaaacaggt ctttgaagac ctgaccgtag cgtttgagcg tggcaagaag
     1561 tatttaattc ttggggaaag tggttctggc aaatcttcct tggctcttat tttgaccaag
     1621 aatagccaac tgcaagcagg ggatatttac gttgatcaaa tctctctttc agacttatcc
     1681 taccaagcca ttcaagacaa gattgcctat ctgccacaag agggatccct tttccatgat
     1741 acggttctat ataacttgac catgggacgg gaggttccag aagataggct gatgtttcac
     1801 attaagaccg tgaaccttga cagtcgtttc ccaagttatg cttctttgag cgaggaaatt
     1861 agtgatgata gcggactgtc tggtggacaa aagcaacgcc tgctcttgat ccgtgccttg
     1921 ctgcaagata aggatatctt gttgctggat gaaagtctgt ctgccttgga tcaggaaacc
     1981 tatgcagtga ttgaaaatta ccttgcctca ctagctgata agacgctcat tcatatttcc
     2041 caccgcgtgt ccgatgaggt ccttagccgt tatgatgggg tggtacggat tggggagagc
     2101 aattaatact cttcgaaaat caaaatcaga cgttgttgac ttgatttgat gagcgaggct
     2161 gggcaaaaag cacagcaccg cttcacaaaa ttagtgtcaa catctcagcg cagtgattga
     2221 ttggcagatt tgttcgtgtt ttacactcca aatctgacct aatcaactgt gcggggggtg
     2281 ggaagacgaa ctcttctatg aatggtcgag ttctttccca ctcccagcct gttcctttga
     2341 aacaaaatag taacagggtt ctatctgcgt aagtagaaac gaactacgtt cgctctattt
     2401 ccaacctcca aaggttccca aaacctttgg agctagtctg tttttgattt tcattgagta
     2461 tgagtgagaa gatataaaaa tgcccccaag tcatcaactt tgacttgggg tctctccatt
     2521 tatcatgcgg aggaagggat ttgaaccctc acacccgatg ggcacatgcg cctgaagcat
     2581 gcgtgtctgc cgttccacca cctccgcttg ctttttatta tactattttt tatttgaaat
     2641 gactagagta aagtgtaaaa tctcagagtc tgggtaaaag accatctcac ttcataaggt
     2701 tagtgtcaac atctcagcgc agtggttgat tggtagaatc gttcgtgttt tacactccaa
     2761 atctaaccat tacgactgtt gcgaacaaag ttcgctttat atccaacctc aaactgtctc
     2821 ccagacagtt tgagctgtgc gggggtggga ttgaaacagt ctgggaatag actgtttcag
     2881 ctcaacaact tgaaacgtgg aacgggtgac gcgctctttt attaaggttc gagttctttc
     2941 ctgctccttt tttcttagga aatttggtat aataggaaca agtacacaca aaggagtctt
     3001 cattgcaagg aagaattatc aaggccttgg caggttttta ctatgtcgag gcggatggac
     3061 agatttatca aaccagagct agaggaaatt ttcgtaagaa gggacaaacg ccctacgtgg
     3121 gtgattttgt ggacttttct gcggaggaaa actcagaagg ctatatatta aagattcatg
     3181 agcggaaaaa tagtttggtt cgacctccta tcgtcaatat cgatcaggcg gtggttatca
     3241 tgtcggccaa ggaacctgat tttaatgcca atctactgga tcgtttccta gttctccttg
     3301 aacagaagga tatggatccc attatctata tctctaagat ggacttggta gaagatcgga
     3361 cggagatgga tgccttcaag gctatctatg agaaaattgg ctatcctttt gtctatagtt
     3421 tggaggaatt gatgcctctt ttacaggaca aggtgacggt ctttatgggg cagacagggg
     3481 ttgggaaatc gactcttctc aatcgcattg cgccagaatt agccttggaa acaggggcga
     3541 tttcagatag tctggggcgt ggtcgccata ccactcgtgc ggtcagcttc tacaatgtct
     3601 tcggtggaaa aattgcggat acacccggtt tttcatccct agactatgaa gtcaaggagg
     3661 cggaggctct gacagattgt ttcccagaga ttgcggaaag tagccaggat tgcaaattta
     3721 ggacctgtac ccatacccat gagccggatt gtgcggtcaa ggaagctgtt gccagctctg
     3781 ccatttccca aagtcgcttt gataattatc tccaattcct cagcgaaatc caaaatcagc
     3841 gtgaaaccta tactaaagtc agtaaaaaat tcaaatagaa agttggttct ctatgtcaca
     3901 ttttaagatt gcaccgtcta ttttggcggc agattatgca aattttgaaa aagagctcaa
     3961 gcgtctagaa aagacaggtg tggagtatgt gcacattgat gtcatggatg gtcatttcgt
     4021 gccaaatatc agctttgggg cggatgtggt tgcggctatg cgtcctcata gcaagctggt
     4081 ttttgattgc catctcatgg tgtccaatcc tgaaaatcat attgagacct ttgcacgtgc
     4141 aggcgcagat attttaacca ttcatgcaga agcaacggtt cacttgcatg gaaccttgca
     4201 gaaaatccgt gctgctggta tgaaggtggg tgtggtcatc aatccaggta cgccgcttgt
     4261 gaccattgag cctgtgctta acttggtgga tcaggtgctt ctcatgacgg tcaacccagg
     4321 ttttggtgga caagcctaca ttccagaggt tgcggataag attgcagatt tggtcaaact
     4381 ccgtgaagcc aagggcttgg cctttgatat tgaagtggac ggcgggattg acgataagac
     4441 tattcattca gccaaaagtg cgggtgccaa tgtctttgtg gctggctcct atctcttcaa
     4501 aggagacttg gatgccaacg ttgccaaatt gagagctgcc ctcaatgatt aagattgctg
     4561 ttattgcagg cggttccttt gactgccttc ctgagcctgc cgacctctat gtgggggtag
     4621 atgcaggctc tcttcgtctt ctggaccatt ccctgcctct tgactgggct atcggtgatt
     4681 ttgactcggt gacctctgag gagctggggc agataaggga gatggcagag cagtttctgc
     4741 aagctcctgc tgaaaaagat gatacagact tggagttggc tttaaaggaa atcttcaagg
     4801 cctatccgca ggcccaggtt cgcatatacg gagccttggg tggtcgcatg gaccacatga
     4861 tgagcaatct ctttctggtt gcagaacccg acttggcagc ctatatggag cagattgaat
     4921 tggtggacag tcagaacgtc gtccgttttc gacctgcagg cagtcatagg atttcgccga
     4981 ttgctggtat gaagtacatt tcctttatgc cgtcggacca aagccacctg accattcgtt
     5041 atgccaagta cccgctggat gccagcaatt attttttcaa aaaatgctat gcttctaacg
     5101 aatttataga tagggatata gacattcaac tggatcaggg ctatgtggtc ctgatctaca
     5161 gtaaggacaa ggattagatg gatattgtac tacttatttt gctgatactg gtcttgcttg
     5221 ccttggtttt tctttatgga aaatggcaga gcttggccct gcttttgcaa gatcaagccg
     5281 aagatacagc agacaacttg tctgaccagc tcagctatca actagaaaat gcaactctca
     5341 aacagcagca gaccattcac caggaggtgg aaagactccg cacggagctt taccaacagc
     5401 taaccgacat ccgtcaagag ctgaataaga gccacttgga aacgcgagat gccaccgacc
     5461 ttcgtttgca ggccattcag gagtccaatg aaaaacgcct ggaagaaatg cggcagacgg
     5521 ttgaggaaaa gctggagaaa accctgcaaa cccgcctaca agcctccttt gaaatggtgt
     5581 ctaagcagtt ggaatcagtc aatcgtggtc tgggtgaaat gcagacggtg gcgcgtgatg
     5641 tgggtagtct taacaaggtg ctgtctggca ccaaaacccg tggcatcatg ggtgaattgc
     5701 agctgggaca gattatcgag gatattttga cacctagcca atatgagcga gagtttgcca
     5761 cagtttcagg ctctagtgag cgtgtggagt atgcggtcaa gctaccagga cggactgagg
     5821 gagactatat ctacttgcca atcgattcca agtttccgct ggcggactat tatcgcttgg
     5881 aagatgccta cgaaagtggg gataaggacc agattgacct ccatcgcaaa aatctcctgg
     5941 cagctatcaa acgttttgcc aaggacattc agagcaagta cctcaatccg cctgaaacca
     6001 ccaactttgg cgtcttgttc ttgccaaccg aagggctgta ttcagaagtg gtccgcaatc
     6061 ccattttctt tgatgagctt cgccgtcagg aaaatatcgt agtagcagga cccactaccc
     6121 tttctgccct gctcaattcc ctctccgtcg gctttaagac ccttaacatt caacggtcgg
     6181 ccgatgatat ttccaaggtc ttgggcaatg tcaagctgga atttggcaag ttttctgacc
     6241 tcttggtcaa ggcccagaaa cagctcaatc aagctagcag caatattgac aaactcctaa
     6301 ccactcgcac caacgccatc gagcgtagtc ttcgtaccat tgacctgtac gaagatgacc
     6361 aaaccaaggg gctgcttggc ctgtccccat tagatgagga agataatgaa aattaaccaa
     6421 atgaaaaaag atgaattctt cgaaggattc tatctaatca agtcagcaga agtccgacaa
     6481 acacgggctg gaaaagacta cctagctctg accttccagg atgatactgg tgagattgaa
     6541 ggcaagatct gggatgccca accagggaaa atcaaggatt ttactgctgg aactgttgtt
     6601 cacatgcagg ggtgccgtga ggtttacaac aacacccccc aggtcaatca actggttctt
     6661 cgtttgccaa aggcaggcga gcccaacgac cctgctgatt tcaaggaaaa accacctgtg
     6721 gatgtcaagg acaccaagga ctatttgagc cagatgattt tccgcatcga aaatgccact
     6781 tggcagcgga tcgtccgtgc tctctacagc aagtacgaca aggaattcta ttcctatcca
     6841 gcagccaaga ccaatcacca tgccttctac tcaggcttgt ccttccatac agcgaccatg
     6901 gtacgcttgg cagataaaat tggtgacatc tatccccagc tcaacaagag cctgctcttt
     6961 gcaggaatca tgcttcatga cctagccaag gtgatcgaac tgactggtcc agacaatact
     7021 ggctacactg tccgtggcaa tctgattggt cacatttcct tgattgatga agagattacc
     7081 aaggtcttga tggaattggg catcgatgac agtctggagg aagtgactgt tctgcgccac
     7141 gttatcctca gtcaccatgg gctcttggag tatggaagcc ctgtccgtcc gcagattatg
     7201 gaggcggaaa tcctccacat gattgacaac attgatgcgg aaatgatgat gatgctatcg
     7261 gccttggaca aggtcggccc aggcgagatg accaaccgca tctttgccat ggataatcgc
     7321 gccttctata agcccaatat cgactgatgg cagttaggat agtgtctcga cagcccctca
     7381 ccaaaggctg gtccacggac caaaagtaca aggtccagct agaagatggt cgccttggtc
     7441 ttttgagaat agcagagcgg ccagcctatg aggctaagca attagagttt cagttagttg
     7501 aaaacctgtt tggtctaggt ttgcctgtgg cagagccact aagtttttgg gcggatgact
     7561 tgtcagtcta caccctttat gaatggatgg aaggtcagga tatgaatgac ttggctacca
     7621 gtctgtcaga acaaacctta tatgaattgg gctgtcagtc agggaagttt ttgcgaacct
     7681 tgcatgccct accgattgat caaagtctgc gcgactggaa cagtttttat caggctaaga
     7741 ttgacaataa attagctgcc taccaagcag ctagtcattc ctatccaaat ggtcaagcca
     7801 tgatagcctt tgttcaggcc aaccgtcact tgcttgaagg gagaccgatt gcctaccatc
     7861 atggagattt tcacacaggt aactttctac ggggccagga tggaagactg aaaattttag
     7921 actttgaccg ctacgacata ggagacccct gggaagaatt taaccgtttg attttcacgg
     7981 cagatttgtc tccagccttt gcgcgtggtc aggtagatgt ctattttgac ggcgctattc
     8041 cagaggaatt ttggaaactc atggctcttt atgtaacagt aaatagtcta ggcgctcttt
     8101 cttgggcaga acaagtagat tccgaacaaa ttccattgat gaagttgcaa gcgcagaaga
     8161 tttctgaatg gtatgaatat tttaatcatc atcttccaaa gtggtatatg taagcgataa
     8221 acaaaatacg aaaaagacgg acttttcaat caaaaaagtt cgctttttgt agtttgttgt
     8281 gatataatag aaaaaagtga aagaggatga ttttatgaaa ttaagaagaa gtgagcgtat
     8341 ggttgtcatt tccaattacc tcatcaacca cccttatgaa ttaactagtt tgaatacctt
     8401 tgcggaaaag tatgaatctg ccaagtcatc tatctcagag gatattgcca tcattaaaaa
     8461 ggcttttgag gaaagctcta tcgggcatat tgaaaccatt actggtgcca gtggaggagt
     8521 tgtttttact ccatcgatct ctaaggcaga gtctgtcgaa attgcacagg cccttcgtga
     8581 tcagatggcc gaaagtaatc gtatcttgcc aggcggttat atctattcat ctgacttgct
     8641 gtctacacca catattttga aaaatgtcgg tcgtatcatt gcagatgctt tcaaagatga
     8701 gaagattgat gcggtcatga cagttgcgac taagggggtc cctttggcca atgctgttgc
     8761 caatgtcctt aatgtaccgt ttgtgattgt gcgtcgtgat ttgaaaatca cagaaggttc
     8821 aacagtttct gtcaactatg tgtcaggatc tagcgaccgt atcgaaaaga tgttcctgtc
     8881 taagcgtagt ttgaaggcag gaagccgtgt cttaatcgtc gatgacttct tgaaaaatgg
     8941 tggcaccatc aatggtatga ttagcctctt gtctgagttt gactcaacct tggtaggcgt
     9001 ggctgtcttt gcagaaaacc aaaaagggga ccgtagcgta gctaactaca agtctctgct
     9061 cgctgtgacc gacatcaatg tcaaggaaaa tcgcgtggat gttgagttgg gaaatatttt
     9121 tgaataacat acatgcaaaa aagagctggt ttttcagctc ttttttacta ttctttcaaa
     9181 actctccgac cgcgcctcca cgctgatttc ttctaaagtc agcgggtggg tcaggctgag
     9241 tttttgggcg tggagcatga ggcgaggggg agctactcga ctgtaaagcg ggtcgccgat
     9301 tagagcgtga ccgtggtggg ctaaatgaac tcggatttgg tgtgtacgac ctgtttggag
     9361 acgacaggaa actagactat ttttaccaag ggtcttcaag aggcggacct gggtaagagc
     9421 tgtctgcccc ttgcggttgt cgaccactcg ctttctacgg tcatgccggt cccgtccaat
     9481 cttatcggta atagtccagt cagtcatttt tagctggcct tggcagaggg ctaggtagtc
     9541 acggtagatg accttgtctt ccaagagccg attgagaatg ggcaggataa agggattttt
     9601 ggcgaagaga atggctccgc tggtttccat atcgagtctg tggaccacat agcaagtctg
     9661 tcccacatag gcagacacat ggttgagcag ggcaatttct gtcggatcat tgccgtgggt
     9721 tttcatgcct tcgggcttgt tgacgataat gaggtgctca tcttgataga gttcctccac
     9781 caagtccgcc tgtcccagag gaatgctttt ttcaggataa tcttcctggt caaaggtcaa
     9841 ttctaacaag tcgcctgcgg taatcgggca ctgccagtta atcagctcac cgttgacacg
     9901 gacctgtttc ttggtgcgga gaaagtggcg aatttttctg ggaatgagaa aataatcttc
     9961 caagacttcc ttgacagtca gttgaggaaa ggcttgggga atgcgaatat caattttcat
    10021 cttataggct ggttgagtgc ttgggttgca ctttttcgtt tggattgagg tagttcatgg
    10081 cattgttaac agcggttggg gcttcgccca gtccagtcgc gatcaggtca atcttgccct
    10141 cgtagaagca acagtcaccg atggcataga taccagggac agaggtttct tgcttgctgt
    10201 tgacgacaat gcggtggcga ttgagttcca atccccattc tttcagcgtt ccgacagatg
    10261 atttgaaacc gtagttgaca aagaggtggt caaaagacag ggtcagcttg tcctcgctct
    10321 tcaccttatc gaaatcaatg gcagaagctc tgccattttc cccagaaagc cctttaggga
    10381 taaaaggtgt gtgaatggtc acgctggact gcttgagctc ttccacgctg tgctcaaggg
    10441 ctcggaagtt atcgcggcgg tggatgatct gggtggtctt ggcgatcttt tcaaaggcca
    10501 gggaccagtc gaccgcagag tcaccaccac ccaagacgac gatgtccttg tcggcatact
    10561 gctggatatt agacacgtgg taatggacgt tgtcaaagct gtcagcacca tcaatctcca
    10621 gcggacgagg cttgaaggcc ccgccaccca tagcgataat cagggtcttg gtctggtggt
    10681 tgcccttgtt ggttgttagg gtaatggttt ccccaggttc gatagcagtc agggtttcat
    10741 tgaggcagat ggtggtgtca aatggagcca gctgggcaag gaggttgtcg gtcaactcct
    10801 gtcccgtcag gcttggaaag gctggaatgt ctaaaatggc cttctcagga tagagaatgg
    10861 caggctggcc acccagttgg ggaagggagt caatgatttt gaccttggct tgacggagat
    10921 gggcgtagaa ggcggcgaag agaccgactg gtccgccacc gatgatagta atgtcatata
    10981 cttgtgtcat aggaatcctc ttctttgttc agaatgaccc tattttatca tatttttgga
    11041 aaaaattccc tgtatgttgt cacaagttat cgcaggcttt tttctgctag tttttaggaa
    11101 atggtgtata atggtacaaa attcactaga aagaggtaaa gtatggacga tttgcaacat
    11161 cagccgattg aagttccaga agatttccaa attgatcatg aagaccgacc tagccgtcgc
    11221 cacaggggaa atcgtggctc tattgataaa ccaaagaaaa aatcacgtat tccggagccg
    11281 attcgtaaat tttggcgccg ttatcaactg actaaaattt taatcatttt aatggtcctg
    11341 acagttctta cagtaggtgg ctatctattt ttccttgcaa agacagctaa tgttggtgat
    11401 ttacagcagg cgctaaaagc cacaacgatt atttacgata aagatggtgc ggaagctggg
    11461 acattgtctg gtcagaaggg gacctatgta gagctggatg ctatctctga taatttagag
    11521 aatgccgtta tcgctacaga agatcggagc ttctacaaaa attcaggcat taattaccag
    11581 cgtacaattt tggctgcctt gacgttaggt cggtctggag gtggttcaac tattacccag
    11641 caattggcaa aaaatgcctt tctaactcag gatcagacca tcagtcgaaa ggctcgagaa
    11701 ttctttttgg ctctggaaat caataaaaag tacagcaagc aagaaatttt gactatgtat
    11761 ctcaacaatg cctactttgg aaacggggtc tggggagtgg aagatgcaag ccaaaagtac
    11821 ttcggtattc cagctagtaa tcttactctt gagcaagcgg ccgtcatagc aggtatgctc
    11881 aagggacctg agatttataa tccttattat tctctagaaa atgcagttaa tcgtcgggat
    11941 acagtcctgc aaaatatggt caatgctggt tatattgatc aggcgactgc agatgcaggt
    12001 ttccaagtag acctagccag tcagctttca gatacctata cagggaaaca aagcaattat
    12061 tcctatccat cctattttga tgctgtgatt gctgaggcga ttgagcgata cggactgaaa
    12121 gaatcagaca ttattaataa cggctatagg atttacacag agatggatca aaattctcaa
    12181 gccagcatgc aggtgatttt taatgatgag actatgttcc caacatcaag ttttgatggt
    12241 acccatgctc aggctgccag cgtagctctt gatcctagga ctggtggagt tcgcgccttg
    12301 gttggtcgag ttaacagttc agaggatgcg gtctttcgga ccttcaactt tgcgacacaa
    12361 gccaagcgca gtcctggttc aacaatcaag cctcttgttg cctatgctcc agcagtagcg
    12421 gcgggctggt cgattgatat ggctctggat aaccatacag aaacctacgg cgattacacc
    12481 ttgcataact atgattattc gacttctgat accattccaa tgtatcaagc tttggctctc
    12541 tcttacaatt taccagtagc ttatatagtg aacaccttgg gtattgacaa agccttcgag
    12601 tatggacaaa agtttggact tgatatggaa aatgtcgaga aagttttggg tgtttcaatt
    12661 ggttctggag tggagaccaa tcctctgcaa atggcccagg cctacgctac ttttgcgaat
    12721 aagggtgtga tgaaggatgc ccacctcatc actcgtattg aaacggctag tggaaaggtt
    12781 ttagcagagc atcgagaaac aagtaccaag gtgattgacc gtgctgtcgc agataagatg
    12841 acagcaatga tgcttggtac ctataccaat ggtacgggag tgacagcaga tacggccaat
    12901 tatcatatcg ctgggaaaac aggaacaacc gaaacgagtt ttgatgtcaa tctcgtcaat
    12961 gatcagtggc atattgccta cacacctgat ttggtcatca gtcagtgggt tggttttgag
    13021 cagacagatg aaaatcatta tatagatagc agtagctact ggaaggctcc gtcggtcttc
    13081 cagactgtgg ccaattcaat cttgccatat actgcaggaa gtaagttcga agtagaaaac
    13141 gcctatgcac aaaatggtat tgtagaagta gctccagatg aagctgcgca aactgaatca
    13201 agccttggtc aagaacaggt acaagaaatt tcagaacagg cgaaaaactt gattgagcaa
    13261 accaaacaaa atctaatcga tgcccagtta ccagaacgag caaaaacctt gtgggataac
    13321 ataacgtctt ggtttggaga gttgtcaaat ccataaaaac atggtagaat gaaaaggatg
    13381 gagggcttta tggcactaaa aaaagcaagc ctagcctgta ctgtttgtgg ttctcgaaac
    13441 tattcaatca gcctttcgag caatcccaag ccaacacggt tagaagtaaa taaattttgt
    13501 aaacactgtg gacaatacac tgttcacaag gaaaccagat aggagtcacg catgaaattt
    13561 atcaaagaca ttatccgcat tttaaaagat acgtcttggc caactcgtaa gcagagctgg
    13621 acggatttcg tgtctgtagt ggaatatact gcctttttcg tagcggtggt ttacctcttt
    13681 gacttgattt tgtcacgagg aatcatgagc ttgatcaatc ttttctagaa aatacttgcc
    13741 atttgtaaaa tggaagtgat ataataagga aaagcgaaag ccttcgggct ttttttagcg
    13801 tctaaaaatt ccgtgtttcc aaagaaagga agtaacaatg tacgatagtt ttgataaagg
    13861 ctggtttgtt ttgcagacct actcaggata tgaaaataaa gtgaaggaaa acttgctcca
    13921 acgtgcccat acttataaca tgttggaaaa catcctccgt gtagaaattc caactcagac
    13981 tgttcaggtt gaaaagaacg gtgaggtcaa ggaagtggaa gaaaaccgtt tccctggtta
    14041 tgttttggtt gagatggtta tgaccgatga agcttggttt gtggttcgta atacgccaaa
    14101 tgttacaggt ttcgtgggtt cacacggtaa ccgttcaaaa ccaactccac ttttggaaga
    14161 agaaattcgt caaatcttgg tgtctatggg acaaaccgtt caagaatttg atattgatgt
    14221 caaagttggc gacactgttc gtatcatcga cggtgccttc acagactaca caggtaaaat
    14281 tacagaaatc gacaacaaca aggttaaaat ggttatctct atgtttggta atgataccat
    14341 tgctgaagtt aatttaagcc agattgctga gttgtaataa gttgttaaag cgcagggaag
    14401 cctgtgcttt ttcttgtttt tgagggctaa ttcaaaaaaa acttgccaaa gatttaaaaa
    14461 ttttatagaa ttaggtgtac ctaacttata aattaattaa acttaaaaaa cggaggtttt
    14521 atgaaacaga agtggtctca gattgagaat aaacaacgct ttagtatcaa gaagttaagt
    14581 gtcggtgtgg catcggtatc aataggattt tttatcacgg gtgttccgat ggttcaagca
    14641 gatactagtg gagaaggatt ggagtctaca gttgcggtcg caacagatat ggatagtagg
    14701 caaaattctg cggtagagaa aaaagaagat ggaccattat cagatgatcc agttaaaacg
    14761 gagcaggtgg atgaaccagt tgctgaagag ggagtggtcg aagaagttgt agatacagag
    14821 gcgggtgaag aatcaggtct tctcacagat caagctgcga ccgagataga aactacagct
    14881 ggtaagacaa cagatgagtc aaaggaaaaa gaagacatta gcggaaaaga agctagtgct
    14941 cctcaaacaa tcccgcagga atcacagctt gagccagaag aggtgacaac agggcgctat
    15001 attttacaat tttccgaaga gaaccgaaat cttgtattgg ataaattaaa gaaaattgat
    15061 ggcgttaaaa ttgttcatga gtataaggag gttttaacgg gagcatcagt agaggtaggg
    15121 aaagaaagtt tgtctgatgt gaaggcaatt accgaattaa cctctttaga agagagtcgc
    15181 cgtatccgac cgactcttca tactgctaaa cagctggttg gtgccttaaa agcaagttct
    15241 aaatatcaga cagatggtcg cggaatggtg attgcagtca ttgactccgg tttggatatt
    15301 aagcacaaag acatgaggtt ggatgatggt gtcattccta aaattaagga cattactcca
    15361 tctacgacag ggacatacac attgaaagtt ccccatggct ataattatgt atctggcaac
    15421 gataatctct acgatgatac ccacgaacca catggtatgc acatagcagg aactctggct
    15481 ggaaatgcaa cagacgaaga agttgcgtct aaaaagggag ttgatgggat tgctcccaac
    15541 gcacaactgc tagtctacaa gattttttca aatgacccta aaaattataa agctgagacg
    15601 gaggatgctg cttatgctgc tattgaagat gctatcaaac acggggcaga tgtcatcagc
    15661 ttgagtgttg gttattatga tagcgggcta ccagggaatg cttactacac gattgctaag
    15721 agggcagcag aaaagggaat tatcattaca gcggctattg gtaatgctgg tgcctcctct
    15781 tcagacacct cctttgacct gcatacaaat aatgccttag gagctgtgga tacggcaaca
    15841 acagttggtg tagcagcgac tcccgcagtt atcgcggttg gttcggcgag aaatacccat
    15901 cttgttcaac gagaatttat gctgaatgga cagtcttttg gttactatcc tattggctat
    15961 acaacgctta cagagggaaa atatgaattt gtagatgctg gaaatggtca ttgggaagaa
    16021 gtgcaagggc ttgatttggc tggtaaagta gcggttatca aaaaagataa gtttgacttg
    16081 aaagatgctg ttcgtaattt gaaattcaag gatgttgctg gaattattgt gataaatact
    16141 gatcagggat ggaacaagga ttattatagg acccatcagt tgttggtaga tgataagact
    16201 ttgctttcct actcctctat ctggggaatt agtcttagcg gggaagatgg aaggcgatta
    16261 ttagaagttg ccaaccaatc gcaaggcaac actggtttgg ttcttaaacc tacaattgga
    16321 atgaagaagt tgattgaagt gccgactgta tcaggctttt ctagttgggg acctacggtc
    16381 aacttagaat tgaagccaga gattgtggcg ccgggagagg atgtttatgc aaccttgaat
    16441 gacaatcgtt atggctccat gtcagggact tcgatggctt cgccaattgt ggcgggtgcc
    16501 agcgcacttt tattgccacg gattcgccaa atgacaccac cagaaggcat gactaggatg
    16561 gatttgctga gaatcatttt gatgaatact gctacccctt tggttgatgt tctagattca
    16621 tctgggcatg ctttggaaaa ttctccgaga caacaaggtg ctggtctgtt gcagattgat
    16681 agagcctttg aaacagatgt gattcttcac caccgtctaa aaggaggggt ggaattaaaa
    16741 gaaatagggc gtgagacaga atttgaggta accttggaaa atctgggaaa ccaacaaaga
    16801 agctttgcta tttcagctgg gaaagtgttg actagtcaag atgttcctgt tgatagaata
    16861 ggacgttctg gaaaagtagt taaagagatt catgcgacag aaatcaaggg gtcgagtatt
    16921 catctttctg agcaatccat tcaactaggt ccaaaagaga agagaaccat tcgcctgaaa
    16981 ttggatgcag gagaagcgaa agaccagttt gcagaagggt atatttactt caaatcattg
    17041 acggaggggc agtctgacat cagcatacct tattttggct ttgttggtga ctggtcaaaa
    17101 gaaaggattg ttgatgcacc ggcttgggaa accagttcta aattgaaact gacctcagtt
    17161 ttatctagct ataaacacaa taagtctggg cgctatattg aacttgggcg tgaaaagatt
    17221 caagataatc aatcgcctct caatccagac aatatcgcaa ttcaaaacca gcattcggac
    17281 agtcagattg ggaatgcctt tgttcgattt gcgctattga gggatattac caactatgat
    17341 ttggatattg taaaagaagc tacagaagat gctcctgttt taaggcgaat tgatacagga
    17401 accatgctgt ctcgtgttcg ctatgtagat tattttgaaa gtctatcgga gtattccaag
    17461 cttcgtactc cgatagaatt gcaccgttgg gatgggaaag tgtacgatgc aagcaatgat
    17521 gaaaatatac cagcaccgga aggacaatat ttctttagat tgcgggtaaa aaataaagaa
    17581 aatggggcct atcagtatac ctatctgcca gtcaaaattg ataatcaaaa gccagagatt
    17641 gtcgcgattg ataccaatcg tctatccagc catagagaac tggtcgtcac agccaaggat
    17701 aataataaag tttgggaggt tcgagctaat ctaaatggag aagatcttct tgttgaaaag
    17761 gttgtagatg atgcaggtca actacattac catctcaaag aagtggaact gccactcgat
    17821 gctaaaaatc atctccgtgt tgaggtgatg gatatagcgg gtaatgtggt tgctgttgaa
    17881 aaagatttga tggcgcctgt aatccagttt aaaaatttgg aagatttgat ggcaattcgc
    17941 agtaagaaaa ctgtagaaat taaagcgaac gtctcagcgc aagtttccga tgtacaggct
    18001 aacttggatg ctcaggctgt gaattactct cttgagaatg gtcaactatc tctccagatt
    18061 ccagagcaat cagatggacg tcatagtttt gaattaatct tgaaagataa ggatggcaac
    18121 cttatttaca ctaaaacctt gaattatttg gtagataatg aaaagccgac gattgatctt
    18181 gatattgaaa aagatgaaga ggatgaagag gttatccaga ttggtaaaaa tgggcgtttt
    18241 acattgaaag ggaaagtgag tgataatgtt agtcttccta aggacatcaa actttactat
    18301 tccaatctag acattggtaa gggagagcgg aaaatcatag atgtaaaaga agacggcagt
    18361 tttgagcaag acttctttaa atctgatttt cctagagcca tcatgttaac tgcggtagat
    18421 gagaagggaa ataaattaaa ggaccttcgt atcaatacaa gtccagagag tctggatgag
    18481 gaggaggaaa cagaagttcc gattactgtc aataactggc tgattgaccc aattcgtttc
    18541 aataaagaaa gtcttggtcg tgagctagat agcgggttgg tcgacttcaa aaagcaagaa
    18601 gatgggactt atctatttac atttgaaata gaagcagaaa ccgaacaagc tcattctgtg
    18661 cgcatcaatg gtggtgaaaa acgctatttt gaggatggga agttgaccta tccagttact
    18721 ctgattgaag agggaaatgt tgtggatata agtgtgtaca atgaggcaga tgagttgact
    18781 tacacgaaga aatatcagat gttggttgat acagaaaacc ctgttttaca gctggaaaat
    18841 gaggtgctac cattggaaag acaggtagtg gatagtgaag aagatgaaga cgaggaaaat
    18901 cagtatgcag gagtcctcct ggcagatgct gatgggcact tgacacttac cggaagcgcc
    18961 aaggataatg gaatttattg gtccttgaag atcaacgaag attttgtagc tcgaggaggc
    19021 ttctggaggc agtatggaaa taatgaaaaa gcctttcgct atgagctaca tagtctgaaa
    19081 gacggggata cagtcaaact tgatttgagt gacagttttg gaaatgctgt tgtgaagaaa
    19141 tataaggtac ggttaaatga caaggaagta tctgagcagg ttcctgaaaa agaccttcat
    19201 gtggagcgat cagataagga tcaaacccct agcattccta ttctgaaatc ggaagcgcat
    19261 ataccaatgc caaaagaaga gaattcactt gctccgcaaa caggatccac tgaaatcgcg
    19321 ctgttaactg gcgatacaag agaagatggt gtggagcatt tggggaaact tacaaaacat
    19381 gaggagccac taggaatttc tgacgagaga atagaagtgt ccgtacctca cagagaattc
    19441 tttgaaagaa gcggaatagg agagacaggt gcattagcgg cggatactag tgggaaactg
    19501 cctcaaactg gggatagcct gggaagtgtc tttataagta ctttgttagg tctatttggt
    19561 ggagctatgg ccctcggaaa tttgaagcga aaagaatagt aaaaaaccta ggaagattcc
    19621 taggtttttt agaatattaa aaggcggtag acggatttga accgacgatc aagcttttgc
    19681 agagccgtgc cttaccactt ggctataccg ccataacaaa gaatattcta ccgaaaaaaa
    19741 agctgaaagt caagaaaaat ctagtgactg tttgtgactg ataacaaatc tataaaacag
    19801 ttgcgaaaac ataggagaat acgacgaaaa agataggagt actttttgag tattgatggc
    19861 tagtaccact ctctttgttt gatagaaaaa gagtggagca aaaagaatta agaaacactt
    19921 tgggtaagtg aattcatttt tactgcaagg aatgttaagg gaacagaatt acgataatag
    19981 tgcacctctt taagaaagat ttggaggtga tagagtttat ttttgctaaa taaagattaa
    20041 accaagaaga atattccatc taaaacggtt gtttttattt acagtatatt gcaaagataa
    20101 ctcaggtact tgattagatt aactgaaaaa atgtgggaac atgatataat aaattgagta
    20161 agagattaaa aaatagatag gatgacaagc agtgtttctt acaaattttc atataaaaca
    20221 tagatgcttt gtcgcttaga taggagaaaa tcatgattgt tttaataaca ggagcatctc
    20281 acactgggaa gactgtgcta gctcaaaaat tacttgaaaa atatcactat ccttatttat
    20341 caatagacca tttgaaaatg gggttaattc gtagcggcaa tactaaactt tcagtcgaag
    20401 aagatgataa acttacagca tatctatggc ctattgttcg tgaaatgatt aaaactgcta
    20461 tagaaaatga gcaaaacctt attgttgaag ggatctatat cccttttgat tgggcaaacg
    20521 actttgcaac agcctacctt gaccatatca gatattactg tcttgtgatg agtgaaaact
    20581 atattcagaa acactttgga agcataaaga aacatgcacg ccttatagaa aatcgtatag
    20641 atgatgaatg gtgtacgatg gaaagtgttt tagaagaaaa tactcgattt tttagaaggg
    20701 cgaaaaaata tgatgcaaac atcctatgga ttgatgagag ttacgagata gagattgatt
    20761 tatgatagag agacattgta tcacagttta tctaagggat acaactaaga ggaagtaaca
    20821 ccagataggc gttacttcct ttctatttct aagaaataga aagtaaaatg gatgaagtta
    20881 aaaataataa aaaagtagta acataaagag agacatatcc cgatctatga gcttggcata
    20941 atctagagat ttgtgtactg aaatgcttga ttttcaccta aaactttggt atacttacta
    21001 agttgtctaa acaacaaata ctcatcccgg accaattgtg gtcttgttgc cgaaaggttg
    21061 ggctgcaagt cgaagttcgg gagaggagaa aaaacaaaag gagaaatact catggcagta
    21121 atttcaatga aacaacttct tgaggctggt gtacacttcg gtcaccaaac tcgtcgctgg
    21181 aatcctaaga tggctaagta catcttcaca gagcgtaacg gtatccacgt tatcgacttg
    21241 caacaaactg taaaattggc tgaccaagct tacgaattca tccgtgacgc tgcagcaaac
    21301 gacgcagtta tcttgttcgt aggtactaaa aaacaagctg ctgaagctgt taaagacgaa
    21361 gctatccgcg ctggtcaata cttcatcaac caccgttggt tgggtggaac tcttacaaac
    21421 tggggtacaa tccaaaaacg tatcgctcgt ttgaaagaaa tcaaccgtat ggaagaagat
    21481 ggaactttcg aagtgcttcc taagaaagaa gtagcattgt tgaacaaaca acgtgctcgt
    21541 cttgaaaaat tcttgggcgg tatcgctgac atgccacgca ttccagatgt aatgttcgtc
    21601 gttgatccac acaaagagca aatcgctgtt aaagaagcta agaaattggg tatcccagtt
    21661 gtagcgatgg ttgacacaaa cacagatcca gatgatatcg atgttatcat cccagctaac
    21721 gatgacgcta tccgcgctgt taaattgatt acagctaaaa tggctgacgc tatcatcgaa
    21781 ggcaaccaag gtgaagacag tgtagcagca gttgaagctg aattggcagc tgagccagca
    21841 tctacagaat caatcgaaga attggttgaa gttgtagaag gaaaataagt aacgaaggcg
    21901 ttaagaaaag cgttagatat atctaaattc tagcttttta gtccgagtac attctacatt
    21961 atttatcaga cacaaaaaca atcctagagg ggcagggctg agcccgctcc tctattttat
    22021 aaatacaaac aaggagaata gacatggcag aaattacagc agctctcgtt aaagaattgc
    22081 gtgaaaaatc aggtgctggc gttatggacg cgaaaaaagc attggttgaa actgacggtg
    22141 atatcgaaaa agcgatcgaa ttgcttcgcg aaaaaggtat ggctaaggca gctaagaaag
    22201 ctgaccgtgt agcagctgaa ggtttgacag gtgtttacgt tgatggtaac gtagcagcag
    22261 ttgttgaagt gaacgctgaa acagacttcg ttgcgaaaaa tgctcaattc gttgaattgg
    22321 taaacactac tgctaaagta attgcagaag gtaaaccagc tgacaacgaa gcagctctta
    22381 aattggctat gccttcaggt gaaacccttg aagaagcata cgtaaacgca actgcaacaa
    22441 tcggtgagaa aatctcattc cgtcgctttg ctttggttga aaaaacagat gctcaagcat
    22501 ttggtgctta ccaacataac ggcggccgta tcggtgttat ctcagttgtt gatggtggtg
    22561 acgaaactct tgcaaaacaa atctcaatgc acatcgctgc gatgaaacca actgttcttt
    22621 cttacactga attggatgag caattcgtta aagatgagtt ggcacaaatc aaccacaaga
    22681 tcgaacaaga caacgaaagc cgtgcaatgg ttaacaaacc agtattgcca ttgttgaaat
    22741 acggttcaaa agctcaattg actgatgaag tgattgcagc agctgaagaa gctatcaaag
    22801 cagaattagc agcagaaggc aaaccagaaa aaatctggga taaaatcatc ccaggtaaaa
    22861 tggatcgctt cttgcttgac aacactcaag ttgaccaagc ttacacactt cttgcacaag
    22921 tgtacatcat ggacgacagc aaaacagttg aagcttactt gaactcagtg aacgcttcag
    22981 ttgtagaatt tgctcgtttc gaagtgggtg aaggtatcga gaaagcttca aacgactttg
    23041 aagcagaagt tgcagcgaca atggcagcag ctcttggtaa ataattgcta gtcttcattt
    23101 tatctttcat tacttcgtta actcgccttg ccgtacttca gtacagcctg cggctcgttt
    23161 cctagtacta aaagcaaact gatagactat tcaaaatcac aagaacttcc gaaagggagt
    23221 tcttttttgg caaaatcggt cttagggcgg atgtcggata tgcttgattc ggttatacta
    23281 ttatcaatcc taaatatttt tcataatctc cttaaaaagc accggccttg tggtcggtgc
    23341 tttttgttag atttctaaaa tgtaagcatc ccagctaggc ttgtttggtt gtcggaattg
    23401 gtcagctaaa tgcatggcga taggatcgca gtcatcagcc tcaaagctaa tttgctcata
    23461 ctgttcaaat agttggcaaa taactgcttg gatgaaggaa ccaaagcttt gttcatcttt
    23521 tccgcatacg taggcaattt catcggtatc tatgaaggca caattttctg agtctgtata
    23581 aaccagatca ggtaagcctt tttcaaattc ttcttgactg gcagtccaag gattgatgtc
    23641 ttggtggact gtttgatagt ggtcaaaaat ttgctgacag actatttgat aaggtgcggt
    23701 gcctttgagg actatgctta agttggaagt gcctgtttga ctgagatagt cttgcttggt
    23761 cacttcgaac tcataacatt tccgcttgca gacaaagcca gctgtggtaa ggaaatggat
    23821 tctttcctgc tctgcagagg agagcataac ttgaagaggt tttccgccta aggaagtctg
    23881 tagggactgg aagagctgct ttgctatttt gcaatcgaaa tcaaccaaat ctagtcgcag
    23941 atagatattg gtctggtggt agggattttg gttgctgtga atcttgccga gtggtcttcc
    24001 ttgataagag atgtggaagg tgttggcttg gtaggaaatg tctagcatta gtcttgaata
    24061 aaagccgcaa tctcatcttc cgtcatgctg gaatcgcagc ggacttggac accagtagat
    24121 ttagcgacca ggaggcctgg aacagttggg acttggtagt ggtcgcggag ggcctggagt
    24181 tcagggctga cttggctgga gtcaaggaag tggatggtca cttgcttgtc ttgggcaacc
    24241 ttgtggagtt ttggtgcgaa gcggttgcag taagggcagg ttgcacggcc gatgaagagg
    24301 accgctccct cattggcagt tagaaggctc tgtgcctgct ccacgtttac gctggtaaaa
    24361 tcttggatgt agtcttgaaa gttcatgggg ttctcctttt ttttccttta ttatagaaga
    24421 aagcagagca aatttcaaaa attggctacg tttgtgtgga agtgaggctt tcgctttcaa
    24481 aaagtggata aaaatagtat aatggtcaaa gatagtcaaa gaaagaggcg atagtatggc
    24541 gatgaaaaat acgtcggatt atatcgaaga acatatcaaa gcgattttag atcaggtcag
    24601 tgtagccgag ttgcgtcgga gcgagctggc cagtcgattt gaagtggtgc ccagccagat
    24661 taactatgtt atcaaaactc gttttacagc cagtcgaggt tatattgtcg agagcaagcg
    24721 ggggggtggt ggctacattc gcattgggcg gattaccttt tcggacaagc atgagctagt
    24781 ccatgatttg ctgaagaata tgggtgatag cctgtcggca actgtttttg cggacattct
    24841 gcagttgctc tttgacgagc agttgatgac ggaacgtgag ggcaatctct tgttggctac
    24901 tagtacagat gaggttttag ggaacgaggc tagtgaaatt cgggctcgga tgatgtacca
    24961 aattttacgt cgattggata ggaaagagga gtagttagaa tgaagatttc aagagggtta
    25021 cagggtgtct atgaagatgc tcaattgatt gcacagcgtt atagtagtga ctatttggag
    25081 acctggcact tgttgttagc ctttgtcatc aatccagata ccgttgcggg agctatttta
    25141 gcagaatatc ctgcggatgt attggactat gaacgtgcag tttatatggt gatggggcgg
    25201 cgttaccatg aagagttaga gagctttttc tttcttccat cgtccaagcg ggtgaaggaa
    25261 ttgcaggtct ttgccgagaa gattgcggag attgtcaaga gtaaggggct aggaacggag
    25321 catattttca tgggaatgct cttggacaag cgttcgactg cctcacaaat tctggatcag
    25381 gtcggttttc actttgagga ttcggatgat aaggttcgtt ttctggattt gcggaaaaat
    25441 ctggaagcca aggctggctt taccaaggag catctgaagg ctatccgcac catgacgaaa
    25501 ggtggcaagc ccaagcaggc aacggttggc aatatgatgg gcatgaccca gtcacaaagt
    25561 ggtggcttgg aagactatac acgtgatttg acggctttgg cccgctcagg tcagttggag
    25621 ccagtcatcg gacgggatga ggaaatttcc cgtatgcttc agattttgtc gcggaaaacc
    25681 aagaacaatc ctgtcttggt tggagatgcg ggtgttggga aaacagctct ggcactgggt
    25741 ctagcccagc ggattgctaa tggagaggtg ccagctagtc ttgtcaatat gcggatcttg
    25801 gaattggact tgatgaatgt cattgcggga acgcgtttcc gtggggattt tgaggagcgg
    25861 atgaacaata tcatcaacga tattgaagaa gatggtcgag tgattctctt cattgatgaa
    25921 ctccatacca ttatgggatc ggggtcaggg attgactcga tcctggatgc tgccaatatt
    25981 ttgaagcctg ctctgtcccg tgggactttg cggacagttg gagcaacgac tcaggatgaa
    26041 taccagaagc atattgaaaa agatgctgcc ttagtacgtc gatttgccaa ggtgaccatt
    26101 gaggaaccga gtgtagcaga cagcgtagca attttgcagg ggttgaagcc agcctatgag
    26161 gctcaccaca aggtgaccat ttcggatcag gcggtggtaa cggcggtagc ctatgccaaa
    26221 cgctatctga ccagtaagaa tttgccagat tcggctattg atttgctgga tgaagccagt
    26281 gcgacggttc aaaatcgtgc caagggacag gtagaagaag gtggattgac cgctttagac
    26341 caagccttga tggctgggaa atacaagacg gtaacgcagc tcttgcttaa ggctcaagag
    26401 gcggaaaatc aggcgactag ctatagcttg gaagtcacag aagaagacat tttggcaacc
    26461 ctcagtcgct tgtcaggtat tcctgtcacc aaactgagtc agacagatgc caagaagtac
    26521 cttaatcttg aacaggaatt gcacaagcgt gttatcgggc aggaagaggc gatttcagct
    26581 gtcagccggg caattcgccg caaccagtca ggcattcgca ctggtcacag accgattggt
    26641 tcctttatgt tcttggggcc aacaggtgtc ggtaagacag aattggccaa ggccttggcg
    26701 gagatcctct ttgatgacga atctgccttg attcgttttg atatgagtga gtatatggag
    26761 aaatttgcgg ctagtcgcct caacggtgct cctccaggct atgttggcta tgaagaaggg
    26821 ggcgagctga cagaaaaagt tcgcaacaag ccatactctg tcctactttt tgatgaggtg
    26881 gagaaagcac atccagatat tttcaatgtt cttttgcagg tcttggatga cggtgtcttg
    26941 acggacagaa aaggtcgcaa ggttgatttc tctaatacgg tcatcattat gacgtctaac
    27001 ttaggggcaa ccgctttacg tgatgataag acagttgggt ttggggctct tgatttgtct
    27061 aagagtcagg aacacgttga aaaacggatt tttgaggcgt tgaagaaggc ctatcgtcct
    27121 gaatttatta accggattga tgaaaaagtg gtcttccata gcctgacaga agcagatatg
    27181 caggatgtgg tcaaggtcat ggtcaaacca ttgattgccg tggcggccag caagggtatt
    27241 accctcaaat tgcaggcttc tgctcttaaa ctcttggcca aagaaggcta cgatccagaa
    27301 atgggtgccc gcccacttcg tcgcctcctc caaaccaagt tggaagatcc attggcagaa
    27361 atgctcttac gtggagaact gccagctggt gtgaccttaa aagtaggggt caaggccgag
    27421 cagttgaagt ttgatagtgt gaaagcaggt tagacctgct tttctttcgg cttgctatct
    27481 ttttataaaa aaatataaaa aactcttgac tttggtttga gaaaagagta ggatataaaa
    27541 tataaaaaac aataaaaagg tagattatga aacaagcagt agcagttatt tttgggacct
    27601 ttgctcccat gcacaagggt catattgacc tgattcaacg agccaagcgg gaatgcgatc
    27661 gggcggtcgt catcgtgtcg ggctataaaa atgaccgtgg tcatcagatt ggtctcggtt
    27721 tgcagaaacg tttccgctat atccgcgaaa ccttcaacga cgagcctctg gtatccgtct
    27781 ttaagctaga cgaggaggga atgccccctt atccagaagg ttgggcacct tggttagaag
    27841 ccttgcaggc cttggtggcg attaaggaga acgaagagct cgtcttctac gtttcggagc
    27901 aggaatatgc cgaagagttg cgttctcgtg gtttcaaggc ttcctttaca gagcgaaatt
    27961 ttggcatttc agccactctt atccgcgagc agtcggctaa gtattggaat atgattgcca
    28021 agcctttccg ccgtcatttt tctaagaata tcttggtggt tggctctgct tcaaatggta
    28081 aaaccacgct agtgcgggat ttggggcgtt attattcctg tcctgtttcg ctggaatatg
    28141 cccgctacta ccagcaacgt tacaatgtgc gtgatgatga gttgacaggc aaggactaca
    28201 actatctctt gacgggccag tatcgccaga cctcagacct gattgactcg gataccaatc
    28261 gtggtctggt cattgcggac accaacgcga ccgtgacgga agcctactac gactactaca
    28321 tcggcgaaac ttctagttct ttccactcgc tctgtgctga tacggttaag aatgaaaaat
    28381 gggacctgat tatctttgtt ctaccgacag gctcttatgt ggatgacggt tttcgggata
    28441 tgacaatggc tgacgcagaa attcgcaatg cctttaccga acatttgaaa gaactggttg
    28501 ctaaaaatca cccgcaggct tcgctggcct ttatcggtgg gtcttatgca gaaaattatg
    28561 ccaaggctat cgagctaatc gatgctatct atcaggaatt ttaggaggac attatggaac
    28621 aacttaccaa attcatcgac cgttttcaag cttccttgaa gcaggtacca gaaaacatgt
    28681 ctgctatcgc aaatagagcc aaaaaactgg gagttatcgg agttctggac gcaatcattg
    28741 cgggactatt tttcggtcgt accctaggtc agtggctcta cttgctagtt ttgtctagtg
    28801 tgcctgttat cttacatgta tggtctgcta gtgaggactg gatgggcttg tttacctcgt
    28861 ggacagggat tatctgtgtt atcttggtag cagaaggacg gtcaagtaac tatttctttg
    28921 gctttatcag taacctcatc tattttgtct tatcttacca aaatatgttc tatggggaag
    28981 tcatgacagc gattttcttc attgtcatgc agccagttgg cttgtatttc tggctatcag
    29041 cccgtgtcaa tggagcagca gaagaagaga aaacagaatt tgaagcccgt aagctgactc
    29101 tctggggctg ggttaagtgg ttagtcttcg ctgtcttggt atggggaagt tttggcttga
    29161 tttacaagtc aattggatca gctcgtccct tccgtgactc tattacagat ggcaccaact
    29221 ggacaggaca attcctgcaa agttacctct accgtgagca atggattttc tggattgcaa
    29281 ccaatgtctt ctccatttac ttgtggtggg ttggtccaga tagtggtaac ctgcaaatgt
    29341 cggttatgta cttcgtttgg actatcaact cgcttgtcgg ctggtaccaa tggtctaagt
    29401 ccataaaaga agggcaggtg gctcgaaatg gctaggcctg ctggtctatc agacaaggaa
    29461 tactacgaaa aatatgtgac agaggcagaa tttttagact ggtataaaaa gcaggacgct
    29521 ccgcgatttg aaaaaccaag cgtgacagct gatatggtgg tctatagttt tgtagagggg
    29581 agaatcaagc tcttgctgat tcgtcgtgct gcccaccctt gtcaacacaa gctgtccttg
    29641 gtcggtggct ttattgccag aggtgaggat gcctaccaga cctgtcagcg tgagataaaa
    29701 aaagaagcgg gactggattt gccccgcaat catatcgagc aactcctaac ggtttccgat
    29761 tctgagcggg atccgcgggg ctggatgatg actattgccc acttggttta cctgcctagt
    29821 caggccttgg atttggtcaa accaggtcca gatggacggg agccgattgt tatcgatgtg
    29881 gatttcaaga cttcgcagtg ttcttatgag ggtcaggtct tgacggcaga ggattttgcc
    29941 tttgaccatt acgagattgt catgacctct atccagcgga ttcagggacg gatgaagtgg
    30001 aatccaacct ttctcaatct cctgcagcag ccctttaaca tctacgctgc gacagacttg
    30061 gtcaatctta tctcacccga caaaaaaatc ctccacaata atttcctagc caagtatgga
    30121 gactttgtgg aagaagttgg agtggaacga ttgcccaaac gcaaacccag aaagacctat
    30181 cgcttaaaag aaagttcata aaaagataaa gaaacctcca gctcaaactg gaggttttga
    30241 tatagtcgaa tgaattagct ttcagacaag gaactgaggt gcaggctgta ctagagtacg
    30301 gcaagccgaa agtgacgatg tatcaaagtt aattcattcg actatattat ttagcaatcc
    30361 gttcctgata ggcttctcgt gcttggtcaa agagttcttg gacctgctcg atagtctctg
    30421 ctcgggcaac agcaccacgg attttggcag cgcctgctga accacggagg tagtgagggg
    30481 caagaccacg gaattcacgt acggcaatgg actcaccctt aagattggtc aatcgggtca
    30541 ggtggtcgaa ggcgacattg agtttgtcgt caaaggagag gtcgggtagg acttctcctg
    30601 tttcaagata gtgattgatt tggttgaaga tgtatggatt tcccatagca gtccgtccga
    30661 ccatgacagc gtcggcaccg acttcctcga ttcgctggcg ggcatcttct acattgcgga
    30721 tgtcgccgtt tgcgatgaag ggaatcttgg tcaggctgcc agctaccttg gtcaaggtct
    30781 ctaggtcaac tgttcctgtg tacatctgct cgcgggtccg tccgtgcatg gccagggcag
    30841 ctacaccgcc actttctgcg gccagggcat tttcgaccgc caggtcggta ttgttccaac
    30901 cggtccgcat cttaacggtc aggggaatat cgaggaccga ggttacttcc ttgatgatgt
    30961 ggtagatctt gtcgggatcc ttgagccact tggcaccagc ttcgttttta ataaccttgt
    31021 tgacagggca acccatgttg atatctacga tattagcctt ggtgttcttc tggatgaagt
    31081 cggcagcccg tttcagtcct tcggcgtcgc cgccgaaaag ctggatagac atagggtatt
    31141 cgttgtcgtc gatatggagc atgtggaggg ttttctcgtt gttgtagaga aggccttttt
    31201 cagaaatcat ttccataacg accagtcccg ctcccatttc cttggcaatg gtgcggaagg
    31261 ccgagttggt cacgccggcc attggggcca gcacgcagcg attggggatt tccacatcac
    31321 caatcatgaa aggggtattg agattagcca ttgatgagtt cctccaaatc gttttcgtca
    31381 aagtggtaat gggtctggca gaattgacag gtgatgtcca cgcccttgtc ttcttctttc
    31441 atctcttgca ggtccgcttt tggtaggctg gctagagcat cgaggaagcg gtctttagag
    31501 cagtcgcaga caaagccgat ttcctcttct gacaggcgtt tgaagtcgtc gtcgccataa
    31561 atggcggata gcagagcttc tatgtggttt tcagaagcca gcaagcttga aatggcaggc
    31621 atttcttgga tgcgtttctc gaaacgggca atttcaacct cggtcgctcc aggtaaaact
    31681 tggagcaaga agccgccagc taccttgacc ttgtcttctt cgtccaacaa cacgttcagt
    31741 cccaccgcag atggtgtctg ttggctgtct gtcaggaaat aagcaaagtc ctcaccgatt
    31801 tcaccagaaa tcaagggtgt catggagttg taaggatgac ctgttccgta gtctgtgata
    31861 accaggaatt gtccgttccc tacaaggggc ccaacgatga cttcgccagt cgctgtccgt
    31921 ttgtagtcca agtcaggatt ttgaatgtag cccttgacct gacctttggt attggcaacg
    31981 gagatgatag ccccaacagc accgctggcc aagattttca gggtgatttt ggtgtcgcct
    32041 ttttcattga cagccaaaat ctgattggca atgagggtgc gacctagagc aacggtggac
    32101 gacgccatgg tgtcgtgttt ttcttgggct gttttcacgg tttctgtgct atctagcaca
    32161 aatgcacgga aatgcccact ttttgatagt gttttaataa ttttatccat aactttaatt
    32221 atagcacaag tggaggtgga gcagtagaaa aatgagcctg aaagtcatgc tttcaagctc
    32281 aaaaaatgat taggattctt tttgtttttt gacaagacag gcgctcaaga atacgagacc
    32341 gattgtgata agtacaaagc ttgtttctcc tcctgtcttt ggaaggattt tcttttgact
    32401 gttgttggca gtaggggtca cggttgtttg tctcttgtct gtagcgccag aacggtcatc
    32461 agcatttaca gctgtttgat tagaagttga aagatttgtt ggcttgttat tgttggtcgt
    32521 accattgtca tcactattat tgactgttcc tgagtcatct gtctgcttgt cgcttggttc
    32581 tggttgagtt ggttcttgtg cctttgtcac atccagttgt accaatagtg gatcgtggtc
    32641 agaagctctg ccatgttctt ccataaaggc tgaattgaca tggaccatat caaaggcata
    32701 gcgctccaac aagttagttg atactagcat attgtcaaga gactgattat ttccgttata
    32761 gaagtaagag aagcgatcgg atgcatcgtg acgactaacg aggttagcca ttcctcctgc
    32821 ttctaaaatt tctatggttt tagtaaattc atagtcattg aagtcgccta gcataacgat
    32881 attagcattt ggattttgag ctaagcctgc ttttgtaaag tcagcgatag tttgtgctag
    32941 tatgtggcgt ttttcttcgg acttgaagct gacaggttgg atttttccgt agagaccatt
    33001 gtcaccgcgt tttgagttga gatggttggc aaggacaacg actttctcgc ctttgaagac
    33061 gaattcagct gcaagtgttt tgcggacagc tgcccaagca gggttggttg ggtcgattcg
    33121 gcctaggctg agattgagtt cgccgttttc ccatgcaact gcctgtgttg cggtaccgat
    33181 tggtttgtca gataggctga cacgttttga gttgtagagg aagccgacgc gaatattgcc
    33241 tccctcttgt ccgccgtctt tgttgttttc aggagcaatg tctacatagg tataggttgg
    33301 tccgccggct gcttgaatgg ctgcaatcag gcgttcagca ctcttactag catcagttgt
    33361 gccgtcgttt gtagcaccgt tgttgtcctg cacttcaatc aatccgataa catctggaga
    33421 atgtaggtct gaaacaaagg atttggcaat gcgttggact ttagcgtctg atgttgactt
    33481 actattagca gagaagtttt caatgttata agaagcgata gtcagcttgt catcatttgg
    33541 gataatggtt gttgtttctg gttttgtagc tccttcgtgc aatgttggaa gggtgctatc
    33601 atctacatag actttataat tggtgtaaga gtaggtgact ggtccagcga tacgaccgat
    33661 gaaatagtct cctgatttga cgatttgttt tccatttttc aaaagaagtg gaatgatatt
    33721 ggtattattc ccttcagggc gaaggttgac gcctccaaca ttatttaaag gaagttgact
    33781 agtggcagga gtgacataga tttccttgtt ttttagtggg ccaaggattt ttgcatcatc
    33841 cacggcaacc accatgcctt caacggattc ccagaaatcg agcgcatctt gttctggatc
    33901 aaattgagcc aaaccgtcgt tgtcaataat atctgctggg atagtccgat caagaccgag
    33961 gactatagga gatggtacag gtgcagtccc atccacagtt acttcagtag ctcgaatttg
    34021 tgtgatggtt aagtctgttt tgtcacgttc agcataccct ctgccctggt attcttctac
    34081 tcgtcctgcg atagtgacaa gatctcctac cttgacattt gtttttaatt tgtcagtaaa
    34141 gatgttaatg ccgtcagatg ttttggtgtc tccatctggt gtgacatctt gcacgtagaa
    34201 gttattggca gaggtaacgt aggttactac gacattttta agcataacag attgattcac
    34261 cagaggtgac tggtgacttg caccttgaat gcgaccgact gttacagctt cggtctttcc
    34321 tagtcctgct tccgtcgttg ccttttcaat gacttcaaaa tgagagaggt caaatggttt
    34381 taattgtatt tttccgttat aggtggataa aatagcggtt agattaatct tatctccctt
    34441 gttgatccgg ttcaaaagat ccgccgtttt gatgcctgtt cggctatcta agcgtacatc
    34501 aacagtttgt ccttcggagt cagttacggt aaaggtagaa ttttgatagc tatcgctttg
    34561 aatatctccg acagtcaagt tttttagaga aactagtgtt gcctgtgctt gcgttgctaa
    34621 ctgagcgatg tttgtttctg taataggagt gttgaaattc tcagagatag ccttgtggtt
    34681 gctaactgtg gttagttgga gttcgccttt atactcaccc aatgttcctg ttaattggac
    34741 tgtatcacca agctgatagc ccaaggcagc ccctgggtag atatagatac cagcaccgtc
    34801 agaaccctgg aggtaaaaac catttcctcc ccaaccgttt actaggctaa taattttacc
    34861 agaaactgtg tactctgttc cttgtgctcc ggaacgaaca gtagcaatcg gtgtagaaac
    34921 aaggtcactt ggtttggtag ctgtattttc acttgttggt ggctgaacat tagtagaaga
    34981 tgaatctacg atttcaatcg ctgtagctgg tttgatccca gctcgcttca tgtatgtatc
    35041 gctagttcct gtgatgcgaa ccaattttcc gactagttcg ggatgattaa cgaggttgaa
    35101 ttggctacga agaggttctt ttagttgaat agggatagtg tcggctgccg cagtatccat
    35161 gcttgcacca agggctagat ttgttttgtt agtggcgtca aaagcagttc cgctactatt
    35221 aagtggtgca ataagatagc cttgtatcgt gacttccgac ttggttattg caagtgacgg
    35281 ataattctct atcgccactt cagtagcgtg cacagatggt atgggcgaag tagcaagact
    35341 aagcaagagt ccggctgtta ccgctacaga acctacggta tagaagagag aacggtttct
    35401 aatcttcata taaaactcct ttttgttata tatggacgtc ataaaaacgt ctgcagttgt
    35461 tatatacata tagtttaaca gaaaatgagt cgtttggaat acttttttag atataatacg
    35521 gatattttta aaaattcaaa tgaaatggta aaaataaatt ggaaaacgaa acaaaaaacg
    35581 aacaaatcgg ttgggtgatg ggaattggtt cacaaaaaaa gcaccgagat ataaatgatt
    35641 ttcttggtgc catattcatt ttgtttaaca ttagttggga gtttttgtga aggaacaaaa
    35701 gggcaaagca gatatatagt ccttttgttg acttttttta cttcggcgca agaggaactc
    35761 cgtttctgga tttcccgctt caaacaatcc actggtttgt ttgaactcgc tttgccgtac
    35821 tttatagaga ggcaagtctt atttccaact gaggctgggc aaaaagccca ggaccactac
    35881 tcagagttcg tgtcaacatc tcagcgcagt ggttgattgg gtttaacagt ccagtggact
    35941 gttaaaggtt ggagatagga tttgcgaagc aaatctcagc aattcgagtt tcacactcca
    36001 aatctggcct ctacgactga tgcgaacaga gttcgcctta tctccaacct caaactgtct
    36061 cccagacagt ttgagctgtg cgggggtggg agtgaaacag tctggggata gactgtttca
    36121 gctcaacaac ttaaaacgaa aacttgttga cgaactcttt ttatcttggt cgagttcttt
    36181 ctcactccca gcaacctgca gctattgagg cgaacgtgct ttgccctatc cccagccttc
    36241 aaaagttcca cgaacctttg aagtaagcac taacaaagta aggaaaatgg aaaactatag
    36301 ctctggaaat aattttttca aaatcttcgg cgtaatgctc tgaccaggtc ctgcgtaagt
    36361 ataggtgtgc aggtacatgg cagggttaaa gttgagttcg atgcaggtgc agttgggctt
    36421 gttcttgctt gctggcttgg tgcggtcggg gataatcaag tccacaccgc aggcccaagc
    36481 tcccatagca gttgccatat cggcggccag ttgcttgtag gactcgtcca tctggtcggt
    36541 catatcgatg gagtcaccac ccgttgagat attggaattg ccacgcagaa aggcttgaat
    36601 gccctctggc aaaactgtat cgggtgtgta gccctgctgt tctaacataa gcagttcgat
    36661 gtcgcccaag ttaatgatct ccagcggtga acggtggtca cgccctcgca gtggatcttg
    36721 gtttttttgc tctactaatt cacggatggt tgagctaccg tcccccacga cattggctgc
    36781 gacgcggagc aggacagcct cgcacttgcc atcaaggatg aagaaacggt actcggttcc
    36841 cgccacgaat tcctccacaa gcacatggct atcttccgaa aaggcgatgt ccagggcttt
    36901 ttcatagtcc gcaaggctgg ctggctcctg gaagatagag atgccaaggc cgaagttggt
    36961 agattttggt ttgataacaa tagcagagct ggctacctgt ccgtaatacc gcagggcatc
    37021 tgtcttgttt gcaaattcag ctcccgcagg tactggaaaa ccagcctggt ccaaaatctt
    37081 cttggtcacg accttgttgg ccatggctag aggaatgacg taattgtcct tcgaagtcat
    37141 gttgccattt ttgatgtact cgacatggtt accatgccag agtttgagaa actggtcttc
    37201 ttcatctaaa atctccacat tcaagcccaa ctgaatggcg tcaaagagaa tcatctgggt
    37261 ggagagttcc atgttttcat agcccttgag ggcgtaaggg gctgtccaag catagtcatg
    37321 aaagacttgt ccctgctgct gaccgaactt ctctagagac ccatcttcaa cttgctctgc
    37381 tatttttccg gaaagggtca aacgagggtc ttgaagtgct gcctccgcat gtgcaatgag
    37441 ttggccatag tagtcatcca gtccaaagtg tagaactatg gctttcatgg ccgtcaagat
    37501 tggcgtggca tcggcatcgt taggtagagg tgtgtgtggg tgactgaggg cgatgagatt
    37561 gttaagttta tctgcttttg ctaaggtgtt atcaacatct gtcagttggt ctaaccaaag
    37621 aagagataag ataaagaggt ggactgtatc aagggtttct tgactaatag caagcgggtc
    37681 ataggggttc aggtcgaagg aacggaattc taaataagaa atccccttgc tgaggtagtc
    37741 acggctagtc tttgctccac gtagtcggac agaagagtaa aattccttct cagcggatag
    37801 ttgaccagat tggacagctt gttcgatgtc ggccacgtac tgttggagag aagaaaagga
    37861 aatatgaaca tcatcggagt tgacatagcc gtacttggaa ttacgaatgg aacggacgca
    37921 accgacttcc gtggttagga atcctttttc ggctaggcta cttgctccat ataggtaggt
    37981 taagagccaa cgatagttga ggaagttttg tgctaatttg aggtagaggg tatttttgaa
    38041 tgcgataaaa tctgtttcct cgcttaattc aaaaagttgt tgggttaagt cttttcctaa
    38101 ttcaaaatta taatggatgc cagacataga ctggacgagc ttgccatagc gttcccccaa
    38161 accgacacga tattggtact catagtcgct gtctagttga gcaatttgga tttcctcttc
    38221 tgaaatcaca ggtggcatgg ataggggcca gaggtattct tgcttatcca tagaacgtgc
    38281 ggcaacatct gtaatggctc ccagtaggcg acgcgcttcc ttagtcgact gagcgattgg
    38341 tgtaatcaac tctaactgtg gctcgctgta gtctgtctgg atataggggt ggaagctacg
    38401 agaacccagt ttatgaggat ggggagtttg tgcaactctg tggtttgaat tgatgcgaag
    38461 tgattcgcgc tcaattccaa aagtagcctg aagaatgggg ctgtttggtg ataatttttg
    38521 taacatatct aagtccttta tatttctgtc aaagtcttat tccaatttta tctagattgg
    38581 agagcaaata caaatttctg ctacgtttct ggtgaaaaat gtactgaaaa tcactgaaag
    38641 taaacaaaga cttcggattt ctctgccaaa agcatattta cacatgtcta cctcgtgtgt
    38701 ttaatcggat ttttttaaaa tatactttta aaaaaataaa aacattcgat atatatgaaa
    38761 ttattggaat ttcttgaaaa aatgttcgtt ttttgataga atagtgtgta aaacgaaact
    38821 tgcaggtgag attcctgcca gaagtagaag aaaggctggg ctggttagcc agttcagaga
    38881 aagagtgaat atgacatcag tagttgttgt aggaacccag tggggcgacg aaggtaaggg
    38941 taaaattaca gacttcttgt ctgctaatgc tgaagtaatc gcacgttatc aaggtggtga
    39001 taacgctgga cacactatcg ttatcgatgg cacgaagtat aaattgcact tgattccgtc
    39061 aggaatcttc ttcccagaaa agatttctgt aatcggtaat ggtgtggttg tcaatccaaa
    39121 atctttggtg aaggaaatca actatctcca tgattcaggt gtgacaacag ataatttgcg
    39181 gatttcagac cgcgcacatg tcatcttgcc ttatcacatc aaattggacc agttgcaaga
    39241 agagtctaaa ggtgagaata agattggtac aaccaacaag ggtatcggtc cagcctacat
    39301 ggacaaggct gcgcgtgttg gtatccgtat tgcagacctc ttggacaagg agatttttgc
    39361 ggagcgtttg agaacaaact tggctgagaa aaaccgcttg tttgagaaga tgtatgagtc
    39421 aactccgatt gagtttgacg aaatctttga agaatactat gcttacggtc aagaaatcaa
    39481 aaagtatgta acagacacat ctgttatttt gaacgatgcc ctcgaccaag gcaagcgtgt
    39541 cttgtttgaa ggtgcgcaag gagttatgtt ggatattgac caaggtacct atccattcgt
    39601 tacttcttca aacccagttg ctggtggtgt gacgatcggt agcggtgtcg gcccaagcaa
    39661 gattgacaag gttgttggtg tatgtaaggc ctacactagc cgtgttggtg acggaccatt
    39721 tccgactgaa ttgcacgatg aaatcggaga ccgtatccgc gaaatcggta aagagtacgg
    39781 tacgacaact ggccgtccac gccgtgtcgg ttggtttgac tcagtggtga tgcgccatag
    39841 ccgccgtgtg tcaggtatta ccaacttgtc cctcaactcg attgacgtct tgtcaggtct
    39901 tgggaccttg aaaatctgcg tggcttatga cttggatggt gagcgtattg accactaccc
    39961 agcaagtttg gagcaactca aacgttgcaa accaatctac gaagaaatgc caggttggtc
    40021 tgaagacatc acaggtgtac gtagcctgga tgaattgcca gaagcggctc gcaactatgt
    40081 tcgtcgtatc agcgaattgg taggcgttcg tatctcaacc ttctcagtag gacctggtcg
    40141 tgaacagacc aacatccttg agagtgtatg gagcgcaaaa tagtgtgcga agactgaacg
    40201 aaagttcggt ctttttctgt ttggtcgaac tttgctttct tgtccagaat ttgatataat
    40261 catgcttatc aaacaataaa agaggtaaac aaatggaagg tttatttttg ccacttgtca
    40321 tggttgccat gattggtttt atgttctatt cgcaacgtaa acaacaaaaa caacgtcaag
    40381 aagcactaaa tcaaatcaaa aaaggtgatg aaattgtgac cattggtggg ctatttggta
    40441 ttgtcgatga aatcgatgat aagaaggttg ttctcgatgt tgatggtgtt tacttgacat
    40501 ttgaacgtgg tgctattcgt gatcgtgtag caagttcaga tgctacatcg gcagttgttg
    40561 aagaagtggc agttgaaacg ccagaagcaa ctccagaatc tgcaattgaa gaataaggat
    40621 gagaaaccga gggaaacctt ggttttctct tgttttagcc ctgcctgatt tttgctatcc
    40681 taggtaaaaa tatggtataa tgaaacgatt atacaataag gaaaatacca tgtttaaatt
    40741 taattttaaa aagaaagaaa gcattgaaac agcaattgaa gtccctaagc atatcgctgt
    40801 gattatggat ggcaatggcc gttgggctaa aaagcggatg cagccacgta ttatggggca
    40861 taaggctggt atggatgcac tgcaaaaggt taccaagacg gcttctgatt tgggagtaaa
    40921 ggtgttaact gtctatgcct tttctacaga aaactggtct cgaccggaaa aagaagtgaa
    40981 gtttatcatg aatctacctg tggagtttta tgataagtat gttcctgaac tccatgccaa
    41041 taatgtcaaa attcagatga ttggtgacca ttcaaaactt cctgtcccga ctctcaatgc
    41101 gctttataaa gccgaacaaa agacaaaggg taacactggt ttgattctca atttcgctct
    41161 taactatggc ggtcgtgatg aggtgactcg cgcagtcaag gctattgcgc aagatgtctt
    41221 ggatgccaag ttcaatcctg gagatattga tgagaaatta atagcggatt acctctatac
    41281 aggaacctta tcaccaacgt tacgcgatcc cgatctagtt atccgtacaa gtggtgaact
    41341 tcgtcttagc aacttcctgc cgtggcaaac agcctacagc gagctgtact ttacagatat
    41401 tgcttggcct gattttgatg gagaagcact taaattagcg attaaagaat acaaccgtcg
    41461 ccacagacgt tttggcggtg tataaggaga aggtatgaca aacgatttac agaaacgagt
    41521 gatatttggc ggcattgctc tagctatttt cattcccttt ttgttggctg gtgggatggc
    41581 atttcaattt tttgtaggcc tgttagctat tattgctacg gctgaattga ttaaaatgta
    41641 tcgcctagca ccaaattcta tcgagggtgt cttagctatg ttggccagtt tagtcttggc
    41701 tcttccgctc cagaattatt tgacattttt accgacggat ggaaattaca cagcctacgc
    41761 cattgtagta tttttactgc ttggttcgac ggtttttaat atcggtcatt acaactattc
    41821 cgatgttgtc tttccaattg catcaagttt ctatgttggt atcggctttc atagtttgat
    41881 actggctcgt atggatgggc tcaataaagt cttctttgcc ctctgtctag tctgggcaac
    41941 agacattggt gcctacttaa tcggtcgtca gattggtcgg agaaaattat tgccgaaggt
    42001 ttcaccgaat aaaacggttg aaggctttgt aggcggtatt ctttctgcgg tggtagttgc
    42061 tatcattttc ttgattgtcg ataagtcctt gttagcgggc tattcatttg gcatgatgtt
    42121 gttgttggtt gtgattttct cgatattctc acaattcgga gacttagtag aaagtgctat
    42181 taaacgccat tttggtgtga aggattctgg aaaaattatt ccaggacacg gtggtatcct
    42241 ggatcgtttt gacggtatga tttttgtctt tccaatcatg cacttctttg gattatttta
    42301 aggaggtact atgaagggaa ttttagcatt tatatttata tttggtgtga ttgtggttgt
    42361 ccatgaattt ggtcatttct acttcgccaa gaaagctggt atccttgtga gggaatttgc
    42421 gattgggatg ggtcccaaaa ttttcgctca tacaggtaag gatgggacac tttacaccat
    42481 ccgtatcctt cccctaggtg gctatgttcg aatggctgga tggggtgaag ataagacaga
    42541 gattaagaca ggtagtcctg ccagcctcag cctgaatgaa gctggtgttg tgacgcggat
    42601 taatttgtct ggtaagcaac tggatagtct cagtttgcca atgaatgtaa ccagttttga
    42661 cttcgaggaa aaattggaaa tcacaggctt ggtcttggaa gaaagcaaga cctataaggt
    42721 tgatcacgat gccacgattg tagaggaaga tggaacagaa gttcggattg ctccacttga
    42781 tgttcaatat caaaatgcga cagtctgggg acggttgatg accaactttg cgggtcccat
    42841 gaataacttt attttaggga ttctagtatt tattcttttg ttcttcatgc aaggaggggt
    42901 tgccaaccca tcaagcaatg cagtaagtat tactgaaggt ggtgctttgc aggctgcagg
    42961 tgttgtcaca ggggacaaga ttctttcggt caatgggaac acgacagaca gctacacaga
    43021 agttgcaacg attattagta aagcagcaac agatgcaaca acagccccaa gctttgattt
    43081 ggtcgttgag catgatggga aaaaccgtca tgtctccgtt actgctgaac aagtagatgg
    43141 ggcctatcga attggtattt caccgatttt gaaaactggt ttcgttgata aaattgtcgg
    43201 tggtttccaa gaagcgggag cgacagctct tagggttgta acagctttga agaatctaat
    43261 tgcaaacttt gatgttaagc agttgggggg accggttgct atttataaag taagttctca
    43321 agcagctgaa tttggtttgg tttctgtatt ggggctaatg gctgcgctct ccattaacct
    43381 tggaatcttc aatttgattc caattccagc cttggatggt ggtaagattg ttatgaatat
    43441 tctggaagcc attcgcagaa aaccactcaa accagagacg gaatcttata tcactctagc
    43501 aggtgtagcc gttatggtgg ttcttatgat agtagtcact tggaatgata ttataagagt
    43561 cttcttctaa gataatttga aatttatgaa aggaattgaa tgcgtgctaa acgcaggata
    43621 ttctgaaaaa tacgaaagga attgaatgcg tgctgaacgc aggatattct gaaaactaag
    43681 aaaggaactg aacacgggct gaaacctgtg cattcctgat aaacaaaaga tgaaaggaat
    43741 tgaatgcgtg ctaaaaactt tacgaaaaag ataaacctgc ctagtgccaa aggcactgcg
    43801 ttaggtttcc tattttcgtt tcgttttctt aacgcactta tatcttaact atgaaacagt
    43861 ctaaaatgat tatccctact ttgcgggaga tgccttcgga tgcgtcggta attagccacg
    43921 ctttgatgtt acgtgcgggc tatgtccgtc agatttctgc tggtatttac agctacttgc
    43981 ctttggctaa ccgtgtgatt gaaaaagcaa aaaatatcat gcgtgaggag tttgataaga
    44041 ttgatgccat tgaatttttg gcaccagccc tcttgtccgc ggatatttgg cgtgagtcag
    44101 gtcgttatga aacctacggt gacgacctct acaagctcaa aaaccgtgaa ggttctgact
    44161 ttatcttggg tccaacccac gaagaaacgg tgacgctatt ggcgcgtgat gcggtccagt
    44221 cttacaagca gttgccgctt aacatctacc aaatccagcc aaaataccgt gatgaaaaac
    44281 gtcctcgtaa cggtcttctc cgtggtcgtg agtttatcat gaaagacggc tacagcttcc
    44341 atgctagtta tgagagcttg gaccagacct acgatgacta caaggcggct tacgaggcga
    44401 tcttcactcg tgcaggattg gagttcaagg ctattatcgg tgacggtggt gccatgggtg
    44461 gtaaggatag ccaggagttt atggctatta caccagaccg taccgatctc gaccgttggg
    44521 ttgtcttgga caagtcggtt gcttcttttg aggaaatccc agaggatgtt cttgaagcgt
    44581 tcaaggcaga actcttggct tggtctgtgt ctggtgaaga caccattgcc tactcaagcg
    44641 aatcaggcta cgctgccaac ctagaaatgg caactagcga atacaaacca agtacagcag
    44701 ttgtagttga agaagacttg gttaaagttg ctacaccaga tgccaaaacc atcgacgaag
    44761 ttgctgcctt cttgaacgtt gcggaagaac aaactatcaa aaccatgctc tttatggctg
    44821 acggagagcc agttgttgcc ctccttgttg gcaatgatca ggtcaatgat gtcaagttga
    44881 aaaaccactt ggcagcggat ttctttgatg tagcaagccc agctgatgca gagaaagtct
    44941 tcggtgcagg ctttggttct cttggcccag ttggtttacc agaaaacatc aagattattg
    45001 cagaccgtaa ggttcaagat gtgaagaacg ctgtagttgg tgctaacgaa gatggtttcc
    45061 actacacagg tgccaatgca gggcgtgatt tccaagtgac tgagtatgtg gatattcgcg
    45121 aagtcaagga aggcgagcct tctccagatg gacacggggt tctcaacttt gcccgtggta
    45181 tcgagattgg tcacatcttc aaactcggta cacgctattc agacagcatg aatgccaaca
    45241 tcttggatga gaatggtcgt tctatgccga ttatcatggg atgctacgga atcggtgtta
    45301 gccgtctctt gtcagccgtt cttgaacaac acgctcgcct ctttgttaac aagacaccaa
    45361 aaggcgaata ccgttacgct tgggggatca acttccctaa agaattggca ccgtttgatg
    45421 tgcatttgat tccagtcaat gtcaaagatg aagcggcgat ggaattgact cagtctatcg
    45481 aagcaagttt ggttggtgca ggctatgaag tattaactga cgaccgtaat gagcgtgtcg
    45541 gcgttaagtt ttctgacagt gacttgattg gcttgccaat ccgtgtgact gttggtaaga
    45601 aagcagctga tggcatcgtc gaagtgaaaa tcaagggtac aggtgatact gtagaagtcc
    45661 atgtggacca actccttgaa accttgcaaa tccttacaaa agaaaatgaa taacagaaaa
    45721 agacttggtt gatgatagcc aagtctttgt tgataaaatg ggagtggttc tagtcaccca
    45781 agcctatttt ttatatagtc gaatgaatta gctttcagac aaggaactga ggtgcaggct
    45841 gtactatagt acggcaagcc gaaagtgacg atgtatcaaa gttaattcaa atgactataa
    45901 catatttagt aggatgttat agaggatagc tcctgcgaca cctccaagaa ttgggccagc
    45961 aactgggatc cagctataag accagtcaga atctccctta tttggaatgg gtaggatggc
    46021 atgcatgata cgagggccta aatcacgagc aggattgact gcgtagcctg tcgttgatcc
    46081 tagtgagaag ccgattgcaa atacgataag tcccacgatg attgggccga ggccagcgct
    46141 gacattgtta ggaccaattg caaggattcc catgactaag acagctgtac caagagcttc
    46201 gccgagcaag tttgaagctg tgtgacgaag agctggtgca gtagagaagg tagcaaggat
    46261 tgttccgcta tcttttgttt cctgccaatg tgggtagaaa tggagataga ggacgatgga
    46321 tgccaacatt gctccagcaa attgggcaag taggaagcct gggacttgag cccatggtag
    46381 ggagccgata gatgccattg cgatagtgac agctggattt aggtgggcag gtccaaaaat
    46441 tcctgatatg tagacggcaa ttgttacagc gatgccccat cctagtacga tggtcagcca
    46501 gccgctattt tcagccttgg ttttagagag gatgcaggat gcaaccacac cgtttccaag
    46561 taatactagt atgaaagttc caagtaattc tccaatcaga ttcataatga cctcctattt
    46621 attgattgtc agttctttta attgttcaag aatagtctcc aagtcagctc cagcctgtaa
    46681 gagagctgcg gcagtatagc aaccttcgac gactggtacg gtttggataa gaatttgttt
    46741 gtctgtaaaa tcggcagcaa gttccatgtt cattcgggcg ctacctaggt cgaaaaaggc
    46801 aaggagggta tcagcagggt ttgcttcaac tcgctcttgt acgatttcaa agctggtacc
    46861 gatgctacca tcttctagtc cgccacagta ggtgatggga atatcttttg cgacttcaga
    46921 tactaggtcg atgattccct gggccaaatt ttttgaatgg gatacgagta agataccaac
    46981 ctttgtcata gtcctgcctc caacatggct tcaaagagaa gtccagatga gaaagagcct
    47041 ggatcaatgt gtccaataga cctttcccca acataggacg cgcgtccctt ggtcgcagca
    47101 atatcctttg tcccttgaac ggctttatgg ataatttccg ttgtcagctg gctttctctt
    47161 agggcagaaa taacaggaat ccacacgtct accatggttt tctcgcccaa ttcagccttg
    47221 ccgcgttttt ggatcatgtc caaacctgct tgaagcgtat ctgccaaatc agcgccagct
    47281 tgactggctt tagtaatacc cataaaggca gagccgtaga gaggaccgga agcaccgcca
    47341 accttgctga gaagttgcat ggcaaccacc ttaaagactt ggtcagcagt ctcatagtct
    47401 ttttcagata gctcctgcat gacggcagcc attcctcgcg ccatgttgcc tccgtgatct
    47461 ccatctccga ttggagaatc tagctcactc aaataatctt tgttttcttg aatttttttg
    47521 ttgaatgttt ccatccagag caatgcttgt tttgcatcca tagtctttct cctaccaagc
    47581 taccacttca acaggggcct gcaaagcgtc aatccagctt gggtcttcta gtttgattaa
    47641 ggtcaatgac agtccagcca tatcaatcga tgtcatgtag ttaccgattt tcttgtagtc
    47701 aacgaccaca ccttttttag ccagcaattg agcaacgtcg ttggcaaaga catattgttc
    47761 catgagagga gttgcgccga gaccgttgat aaggacacca tagtgttcgc catcttgaat
    47821 atcaaagcct tctgccaatt tctcaaccaa ttcttcagcc aatttagcag atggttggag
    47881 tttttctttc ttatagccag gttcaccatg gataccgaca ccgtattcaa attcatcctc
    47941 ttcaaggacg aagcctggtt tgcccacttc tggtaccgta gcacctgata gggctaagcc
    48001 gatagtcttg atttgtggga cgagacggtc agccagttcc ttgatttctg ctagagattt
    48061 gccagttgtt gcagcgtgac cgagaatctt gtggacaagg atggtaccag ctacaccacg
    48121 acggccttgg gtatagagac tattttccac agcgatgtca tcgtccacga tgacactggc
    48181 cacttcgatg ccctccattt ccgccaattc ttgtgccatc tcaaagttca tgatgtcgcc
    48241 ggagtagttt ttgatgacca taaagacgcc agctccctcg tcagcagcct tgatggcttc
    48301 taagatttgg tctggtgttg gtgaggtaaa tactgcgcca catacagcgg cggacaacat
    48361 gcccttgccg acaaagcctg catgagaagg ttcgtgacca gagccacctc ctgagatgat
    48421 gccgacttta ccagtttttt cagccttgcg gataatcaca tcaaatccat cgatacgatc
    48481 gacaagatct tggtgcataa agacaagtcc ttttaacatt tcatcaacga catgttcggg
    48541 ttgattgata atttttttca tgagaaaact cctttgttat tgtttgcgct ttcattttac
    48601 attgtccaaa agaaaaaagg aagggacaga ttgtccaaag tgtccctttt gttccaaaga
    48661 aaagcatgat agggtataat aaagaggaag cgaaaggaag tgacaagtga catatgccaa
    48721 cctcgttgat tacaaagaaa aggattgcaa aggcttttaa aaaacagcta tcccaaaaat
    48781 cctttgataa aatctcagtt gtcgacatca tgcaggaagc agggattcgt cgtcaaacct
    48841 tttacaacca ttttttagac aagtatgagt tgctggactg gatatttgag acagaattgc
    48901 aggagcaggt aactgacaat ctgacctata ttagtggaat caagcttctg gatgagctgt
    48961 tgtactacat cgagagtaac caatctttct ataggcaact ctttgagatt aaggggcaaa
    49021 atgattttgt cagctattta gaaggctact ttatggtttt gatggagaaa attatcaacg
    49081 agtaccagct ccaggagggt aaaatgattt cccaacagga taagcatttt ttgattctct
    49141 atcatgctaa tgcttggatt ggactgataa aggaaggact gacacagtca ccttgtcaga
    49201 ttcacagtta ttggaagcaa atggtggctc ttgttcgcga gtcgtttgtg attttgtagg
    49261 agttaatata tggtgtttat tagaaataga caggcaacaa ttattgaaga ttatttggat
    49321 ggtttctgtc gaactaatcc taaagtgaag aaagtgaagg gacttccgat tgtgcttcag
    49381 aaagtgcagg atgaccattt agttccaatt atttcaggtg gtggatcggg gcacgaaccg
    49441 gcacatattg gatttgtcgg aaagggtatg ctgactgctg cagtatatgg tgaaatattt
    49501 acgcccccaa ccgctgaaga agtatttgca gccattcgcg cagtagataa gggcaaggga
    49561 gtttttctga ttgtaaaaaa ctttgaggca gaccttatct cttttagaaa agccatcgaa
    49621 ttggctcggc aggagggaat tgcagtcaag tacattgtat cccatgatga tatttcggtc
    49681 gatactaaga ataatttccg tatgcggcat agggggcttg cagggaccat tctacttcat
    49741 aagatattag gagctgctgc ccttactggc tatagcctag atgaattgga acagctggga
    49801 ctgtctctgg caacagagat tgcgaccatc ggttttgcaa ccaagtcggc ctatttgccc
    49861 aatgctgccc tgcctttgtt tgatttggag gagggacaaa tatcttacgg tatcggtatc
    49921 catggagaag aaggctatcg gaccgttcgt tttgaatcct ctgagcagtt agccaacgaa
    49981 attgtgaaca aattaaaatt aaaattccgc tggaaggaag gggaagacta tattcttctg
    50041 gtcaataatc ttggatctat gtccgaggtt gagcaaggaa tctttttgaa cgacatttgc
    50101 caatttctag agctagaagg tttacagctt tcctatgtaa aaacaggtaa atttatgacc
    50161 agtcttgata tgggaggaat ttctgtcacc ctctgtcgtg tcaaggatcg aaaatggctg
    50221 gactttttag aagcaccgac agaagctgcg gcttggtagg ctaccaattt ctatagaaat
    50281 cagatctctc aggaaatgaa cctgagagtt ttttcttcct gactcaggaa aaaatacctc
    50341 atttatggta aaatgtttct aacgaactac aaaggaaata agtatgtcag ataagtttca
    50401 actcttgcta caacaaatcg gaatgcctct tgatgcacga caatcagggg ctttttcgac
    50461 tgcaacgatt gagaaagtag tcttgcacaa ggttagcaaa ctttgggaat ttaccttccg
    50521 ttttgaaacc cccttgccgc tcatggacta tcaactcttc aaggctcgtt tggcgacgga
    50581 gtttgaaaag gtgggcaata agattcaatt ttctattgtc agcgatgcgg aggcttttga
    50641 agctggtttg gtagaagcat attatccaga agcttttacg gaagatttgt gccagagtgc
    50701 aggcttcaag gccctttttc agccattaga ggtggcttat agagatggtg ttttgtggat
    50761 aaaaggtcct gaaaccattg acacagatca ttttcggaag aatcatctgc caaatcttgt
    50821 ggagcaatac aagcgatttg gttttggtaa tcttgcggtg gacatccaag tctgtcagga
    50881 aatgacgcag caacaagcgg agattttcca tgcgcaaaat gcagaaattt accagcaggc
    50941 taatgaagaa aacttggcgg cccttgaaca actagctcaa atggcgccac caccagaggc
    51001 agctcagcca tttgtcccag aatataagaa aaatcgtcct gccaaggtca atatcgaaaa
    51061 ggctgagatt acgcctatga ttgaggtgga tagcgaggag aatcggattg tctttgaggg
    51121 actggtcttt gaggtcgagc agaagacgac caagacgggg cgggtcatta tcaactttaa
    51181 gatgaccgac tatacttcgt ccttcacctt gcagaagtgg gctaagaatg aggaagaggc
    51241 tcagaagttt gatatggtca aaaagggaaa ctggctgcgg gtgcgaggca atgtggaaac
    51301 caataatttc actcgtgatt tgactatgaa cgtacaggaa gtccaagagg tcaagaagga
    51361 aatccgcaaa gatctcatgc ctgagggtga gaagcgggtt gagtttcatg cccataccaa
    51421 catgtccact atggatgccc tgcctgccgt tgaggacttg gtggcgcgtg cggcagcctg
    51481 gggacacaag gcggtggcca ttaccgacca cggcaatgtc cagtccttcc cccatggcta
    51541 tcatgctgct cgtaaagctg ggattaagcc cctcttcggg atggaggcta atattgtcga
    51601 ggactctgtg cccattgctt acaacgaagc agatgtagtc ctgtctgatg ccacctatgt
    51661 ggtctttgac gtggaaacaa ccggtctgtc tgcagtcaac aatgccctga ttcagattgc
    51721 ggcgtctaag atgcacaagg gcaatatcat tgcagaattt gatgagttta tcgatccagg
    51781 tcatccgctc agtcaattta caacagatct gacaggaatc acagatgagc atgtgcgtgg
    51841 ttctaaacct ctagaacaag tcctgcgtga gtttcaagat ttctgtcaag attccgtcat
    51901 ggttgcccac aacgcgacct ttgacgttgg ctttatgaat gtcaactatg aacgagcagg
    51961 cttacctatt attagccagc ctgtcattga taccttggaa tttgctcgta acctttaccc
    52021 cgactttaag cgtcatggtt taggtcctct caccaagcgg tttggtgttg ctcttgaaca
    52081 ccaccacatg gccaactacg atgcggaggc gacagggcgc ctgctcttca tcttcctaaa
    52141 agatgctctg gagaagcaca atttgaccaa tctcaaccag ctaaatacgg agctgattgc
    52201 ggaggattcc tataagaagg ctcgtgtcaa gcatgccacg ctctatgtga ttaatcaggt
    52261 tggtttgaaa aatatgttca aactggtctc tctttccaat accaagtatt ttgagggagt
    52321 cccacgtatt ccacggaccg ttctcaatgc ccatcgtgaa ggtttaatat tgggaacagc
    52381 ctgtcaagag ggtgaggtct tcgatgactt gctctccaaa gggatagatg aagcggttaa
    52441 aacggcagcc tattatgatt ttatcgaagt tatgccacct gccctctatg ctcccatgat
    52501 tgccaaggag cagtttaagg acatggcaga gattgaagag actatcaagc agttgattga
    52561 ggtaggacgt agggcaggtc tgcctgttct ggcgactgga aatgtccact acattgaccc
    52621 agaagaggaa atttatcggg aaatcattgt tcgtgctcta ggtcaagggg caccgattaa
    52681 ctggaccatc ggaaatggtg aaaacgctca gccagcacca ctgccaaaag cccactttag
    52741 aacgaccagc gagatgttgg acgagtttgc attcttggga gaaagtctgg cccgtgagat
    52801 tgtcattacc aatcccaatg ccatgctgga ccggtttgaa gatgttcagg tggttaagac
    52861 cgacctttat acgccttata ttgagaaggc cgaggaaacg gtcgcggaat tgacctatca
    52921 gaaagccttt gagatttatg gcaacccctt gccagacatt atcgacctgc gaatcgaaaa
    52981 ggaactgact tccattttag gtaatggatt cgccgtgatt tacctggcat cgcagatgtt
    53041 ggtgcaccgt tccaacgagc ggggctacct ggtgggttca cgggggtctg tcggctccag
    53101 tttcgttgcg accatgattg ggattaccga agtaaaccct atgcctcctc actatgtctg
    53161 tccaaattgt caacacagtg aatttatcac agatggttcc tatggttcag gttttgacct
    53221 gccagacaag gattgtgaaa agtgtgggac caagtataaa aaagatggac aggacattcc
    53281 tttcgagacc ttccttggtt tcgatggaga caaggttccc gatattgact tgaacttctc
    53341 aggggatgac caaccgtctg cccatttgga tgttcgggat atttttggtg aagaaaatgc
    53401 cttccgtgca ggaacggttg gtacggtagc tgccaagact gcctatggtt ttgtccgagg
    53461 ctatgagcgg gattatggca aattctatag agatgtggaa gtagaacgcc tggctgctgg
    53521 agcagctggt gtcaaacgaa cgactggtca gcacccaggg ggaattattg tatttcctga
    53581 ctacatggat gtctatgact ttacccctgt tcagtatcct gccgatgatg tgacagccag
    53641 ctggcagacc acccacttta acttccacga tattgatgaa aacgtcttga aactcgatat
    53701 tctgggacac gatgatccaa ccatggttcg gaagttgcag gacttgtcag gcatcgatcc
    53761 gcaaactatt cctgctgatg ataagggggt tatggctctt ttttctggta cggaaattct
    53821 gggtgttacc ccagagcaga ttgggacacc gacaggtatg ctgggcattc ctgaatttgg
    53881 aaccaacttt gtacggggga tggtggagga aaccaaaccg accacttttt cggaactctt
    53941 gcagttatct ggtctatcgc acggtacaga cgtttggttg ggcaatgccc aggacttgat
    54001 taaggcagga attgctaatc tatctactgt tatcggttgt cgggatgaca tcatggttta
    54061 cctcatgcac gcaggtttgc cacctaagat ggcctttaat atcatggagc gggtgcggaa
    54121 gggcttgtgg ctcaagattt ctgaggaaga gcgaaatggc tacattcaag ccatgaagga
    54181 taacaaggtg ccagactggt acatcgaatc ctgtggaaaa atcaagtaca tgttccctaa
    54241 agcccacgcg gctgcctacg ttatgatggc cttgcgggtt gcctatttca aggttcatca
    54301 cccactttac tactattgcg cttatttctc tattcgggcc aaggcatttg atttggcaac
    54361 catgtccggt ggcttggaac gagtcaaggc taagatggaa gaaatcgccc tcaagaagaa
    54421 aaacaatgaa gcttcgaacg ttgagcagga tctctatacc acacttgaat tggtaaatga
    54481 aatgctggaa cgtggcttca agttcggtaa gttggacctc tacaaatccc atgcgaccga
    54541 ctttctgatt gaagaagata ccctcatccc accatttgtc gctatggatg gtctgggaga
    54601 gaacgttgcc aagcaggttg tggcggcgcg tgccgaagga gaatttctct ccaagacaga
    54661 actccgtaaa cgtggtggat tgtcaggtac gcttgttgaa aaaatggatg aaatgggcat
    54721 cctcggtaaa atgccagagg ataaccagtt gagtctcttt gatgatttgt tttaaaaaag
    54781 gaaatgatga aaaaaagaaa tattttagtt gagttattaa aaggaattgg tctagtactg
    54841 ctttctacta tcttgtggac attgatctta tcttttgcca caccggaatc atcatcaggt
    54901 atttacgaac cttttccagg ttttactgtg attgctggta tactaacgag tttcattctc
    54961 catatcatta tgaagtataa ccaacttcgt caggctgaac aagccgcgaa agctagtaaa
    55021 agtcatatcg ttgttattga agagcgcaat caggccttga tgaagaaagc aaaccgcttg
    55081 gttgaaaaac accagaatct tgaaaaagaa accattttgg acatcaataa atccgtttcc
    55141 aaaattcgaa cggttgaaga aaaaactgtt atgaaatcca ccaagattga aagttcacaa
    55201 gaatttggtc aatttttgcg tcaaatgccg gaattgatgg ccaataaaca tattgaaagg
    55261 ttactgaatg aaatttttga aacagaaaat aatttagcac aatggaagat ttcatacaat
    55321 cagcaggttg agtatttcaa tactctgttg catcagtttc cgattagcgt cattgccaaa
    55381 atcattcgcc tgaaggactt ggaattttat aaggaacatt cgctgactga ttttacagac
    55441 gagatgttgg ggctataaga taaagaaggg tctatcaatg tatcttaagt atttgatagg
    55501 ctttttttgc catctttttg taaattctct gtcactactt tatgaaaatc agactatctg
    55561 ctgtaactag cttaattttc acggagtata aaaaagtcag actaggaatt tgacactact
    55621 tagtaataat gatacaatct ccctatagtg ataaaaacta ctatgtagta acaaatagaa
    55681 aagaggaaaa catatgtcaa actttgcaaa acttcaagaa actcgccgtt caatctacgc
    55741 acttggtaaa gacttgccag tatcaaatga agaagtagta gcacttgttg agaaagccat
    55801 gaaagaatct ccatcagctt tcaactcaca atctagccgt gcagtggtac tttttggtgc
    55861 ggagtcagaa gttttctgga acgaaattgc ctacagcgaa ttggaaaaag taacgcctgc
    55921 agaagctttt gaagctacaa aaggtcgctt agctggtttt gcggctggtg ccggtactat
    55981 cttgttcttc gaagaccaag acgtggtgaa aggcttacaa gaaagcttcc cactttacgc
    56041 tgaaaacttc ccaatctggt ttgaacaagc tcatggtatc aacttgtacg cagtatggtt
    56101 ggcctttgct gagaaaaata tcggtatgaa cgtacaacac tacaacccat tggttgatgc
    56161 acaagttgct gaaaaatacg gtatcccagc taactggaaa ctccgcgccc aagcaccatt
    56221 cggaagcatt gcagctccag cagcagacaa agactatatg gcggattctg accgtgtaaa
    56281 ggtttttggt aactaatact ctgcgaaaat tgggatcaga cgttgttgac ttgatgtggt
    56341 gagtgtaaag ctccagtgga gtttttcagc ctgttccctt aaaacaagag aggagcaggg
    56401 ttatgcctgc agcttgttga cacgaactcc attcgtttca tctccaagct tcaactatct
    56461 cccagagcta accttttcaa cttcctgtat cagcaggaag tttttttatc tgtctagctt
    56521 aaaatatgat acaataatag ggtatttcaa agtacaaagg agaaaaagat ggtattacca
    56581 aattttaaag aaaatctcgc taaatatgct aaactcttgg tttcaacagg tatcaatgtc
    56641 caacctggtc acacggttca attgacaatt ggtgtggaac aggctgagtt ggcacgcttg
    56701 attgtcaaag aagcttacgc tcacggtgct aaggaagtct tggtcaactg gttggacgat
    56761 gtgattgcgc gcgagcgttt ggtcaatgta gatgtggaac tcttggaaca agttcaccca
    56821 caacgcatca ctgaaatgaa ctacctcttg gagcggaagg ccagccgttt ggttgtcttg
    56881 tcagaagatc caggggccta cgacggtgtg gatccagaga aattgtctcg caacgctcgt
    56941 gcactcagcc aggctttgaa cccaatgcgg caagcatccc aagctaacaa aatcagctgg
    57001 acacttggtg cagcatctgg tttggaatgg gccaaaaaag ttttcccaaa tgcaacgtct
    57061 gacgaagaag cagtagactt actttgggac caaattttca agacttgccg tatctacgat
    57121 gaagatccaa tcaaagcctg ggaagagcat gaagcacgtt tggtagcaaa agctaaggtt
    57181 cttaacgacg agcagtttgt caaattgcac tacacagcac caggaaccga ccttgttctt
    57241 ggtatgccga aaaaccactt atgggaagcg gctggttcga tcaatgccca aggtgagaag
    57301 tttattgcca acatgccaac agaagaagtc tttacagctc ctgactatcg tgtggccgat
    57361 ggttatgtaa cttctacaaa acctcttagc tataacggca atattatcga aggtattaag
    57421 gtaaccttta aagatggtga gattgtagat gtgactgctg aaaaaggcga cgaagtcatg
    57481 aagaaactgg tctttgacaa tgctggtgca cgcggtctag gtgaagttgc ccttgtacca
    57541 gataagagcc caatctctca atcaggtgta actttcttca acactctctt tgatgaaaat
    57601 gcctcaaacc acttggcgat tggtcaagcc tatgccttct ctatcgaagg tggtacagaa
    57661 atgagccaag aagagctcaa agaagctggt ctcaaccgct cagatgttca cgtggacttc
    57721 atgattggtt ctaacaagat gaacattgac ggaatccgtg aagacggtac tcgtgtgcca
    57781 atcttccgtg acggtgagtg ggctatctaa aaacaatgct ataagactgg gagaccagtc
    57841 ttattttgta aataaggagg aaaatagaat gttatcaagt ataatcgctg gagccattat
    57901 tggcttgatt gcgggggctt tgacctcatc agatgaccgt cgtggttgtc ttggaaatat
    57961 catccttgga cttgctggtt cgtggattgg acaactgctc ttcggtgatt ggggactaca
    58021 gtttgctggt atggctgtag tgccgtctgt tctaggggct attctcttag tggcgatttt
    58081 tagcagttct agacggaatt aaacacctga accgtgcttc aattggagca tggttttcta
    58141 ttatctggat ttgtacgaat tgccgcattg ttcggatttt tcagaaaatt tccatttttc
    58201 tgttgacaag tgaaaataag tagggtatca ttgtaaataa ttaaaatact gaaaggaaaa
    58261 agtcaaatga aacctgtcac tacaaaattc tttgctttgt tgttgcgacg gtcgggctag
    58321 tgcactaggt agcattagtc ctgtttggct taccaagcgg gcgctgttga caacatctcg
    58381 caggtaatag tcctcgaggt gttttctttt tcttagtata ctttgaaaac taagaaagag
    58441 aacctaatat tgacgttagg gttatttaga aaggtattct tatgcgtgtg attgaatttt
    58501 tagatacgac tttacgagat ggtgaacaga cgccaggtgt gaatttttct atcaaggaaa
    58561 aagtgaccat cgccaagcag ttggaaaaat gggggatttc tgctattgaa gcgggttttc
    58621 ctgcggccag tcctgattcg tttgaagcgg ttcgtcagat tgcggcagcg atgaccaaga
    58681 cggctgtgac aggtttggca cggtcagtaa aatcagacat tgatgcttgt tatgaggctc
    58741 tgaaagatgc caagtatccg cagattcatg ttttcattgc gactagcccc attcaccgtg
    58801 aatttaaact tcaaaagacc aaagaagaaa ttttggcgca aatcactgaa catgtcagct
    58861 atgcacgtga gcgttttgag gtagtggagt tctcaccaga ggatgcgacg cggacggagt
    58921 tggattattt gctagaagtt gtgcagacag cggtagatgc gggtgcgacc tacatcaaca
    58981 ttccagatac agtcggcttt acgactcctc agcactacgg agaaattttc cgttacttga
    59041 caacaaacgt caaatcggac cgtgagatta ttttcagtcc acattgccac aatgacctag
    59101 gaatggctgt tgccaatacc ctttcagcta ttaaaaacgg tgccggtcgt gtcgagggaa
    59161 ctatcaacgg tatcggtgag cgagcaggaa atgcggccct tgaagaagta gctgttgccc
    59221 ttgaaattcg gaaagatttc tatgatgtga ccagtccgat tgttctaaag gaaacgctca
    59281 atacttcgga attagtatct cgtttttctg ggattgccat tccacgcaat aaggcggttg
    59341 tcggtggcaa tgccttctct cacgagtcag gaattcacca agatggtgtc ttgaaaaatc
    59401 catcgaccta tgaaatcatt acacctgagt tggtaggggt caagaaaaat tctctgccac
    59461 tgggtaaact atctggtcgc catgcctttg tagaaaagct gaaagaacta gacctgtatt
    59521 ttgaagaagg agacgttgct agcttgtttg ctcgtttcaa aaacctggca gacaagaagg
    59581 aaaaaatcac ggacgctgat attcgagctc tagtagctgg gacagaaatc agcaatcgtg
    59641 atggcttcca atttaaagat ttgcgtttgg atagtcagtc tgacggaagt attcaggctc
    59701 aggtcatctt catcaatcag gatgaggaag aagtggttgt ttcggagtca ggcaagggtt
    59761 ctgttgaggc tgtctttaat gctattgacc aattcttcca ccaagagatt agcttggaac
    59821 gctaccatat tgacgccatc accgatggaa ttgatgccca ggcgcgtgtg cttgtcgccg
    59881 tagaaaacaa ggcaacggaa acggtcttta atgcctctgg tattgacttt gacgtggtga
    59941 aggcttctgc cattgcctat attcatgcca atgtcatggt acagaaagaa aatagcggac
    60001 agattgataa gaaactatct gagaaagagt taccacacat ctaggaggaa atatgacgaa
    60061 aaaaattgta gccttggctg gtgatggaat cggtcctgaa atcatggagg ctggcctagc
    60121 agtcctcgag gctgtggctg ggcaagtagg atttgattat gagattgagg agagagcctt
    60181 tggtggcgct gggattgatg cgagcgggca ccctctacct aaggaaacct tacaagcctg
    60241 ccgtaaggcg gatgcgattt tgttagcagc tatcggtagc cctcaatatg atgatgccgc
    60301 tgtccgtcca gaacaaggtc ttcttcaact tcgtaaggaa ttaggtctct ttgccaatat
    60361 ccgtccggtg aaaatttttg atagcctgaa agactattct cctctgaagg tcgaccggct
    60421 ggacggtgtg gatttggtca tggtaaggga gctgacaggc gggatttatt ttggagagca
    60481 tatccttgga actgaccaag ccagcgatag caatacctat caagctgagg aaatcgaacg
    60541 ggttgtccgc tctgcctttg acctagccca aaaaagacga aaaaaagtca ccagtattga
    60601 taagcaaaat gtgctagcaa cgtcaaaatt atggcgtaag gtggcggatg aggtagcgaa
    60661 ggactaccca gatgtggtct tggagcacca gttggtggat agcgcagcca tgcttttgat
    60721 taccaatcct agtcggtttg atgtcttggt gacggaaaat ctctttggtg atattttgtc
    60781 ggatgaggcc agcgtattaa caggaacgct aggggttctg ccttctgcta gtcatgcggt
    60841 ggcgggtccc agtctctacg aacctatcca tggttcggct cctgatattg caggtcaggg
    60901 cattgccaat cctgtcagta tgattctatc tgttgccatg atgctggaag aaagttttga
    60961 tttggtccaa gcaggtcaga ccattcgcca ggcagttgaa gcagtctttg cagagggcat
    61021 ttttaccaag gatctaggtg gtagcgcatc taccaaagaa atgacagcgg ccattattgc
    61081 ccaaattgga ggtgggtaaa tatgagtggc aaatctattt ttgataagct ctgggatcgc
    61141 catgtgatta cagggcaaga aggtcagccc cagctcctct atgtggacca gcactacatt
    61201 catgaggtga ccagtcccca ggcctttcaa ggattgaggg atacagggcg atctgttcgg
    61261 cgcccagact tgacctttgc gacttttgac cacaacgtgc caaccgttga tattcacaat
    61321 atccgtgatg tcatttccaa ggctcagatg gatgccttgg ctaagaatat agaagatttc
    61381 ggcattcccc acgcagccca tggttcggaa catcagggga ttgtccacat ggttggacca
    61441 gaaacaggca ggacccagcc aggtaagttc attgtctgcg gagatagcca tacagcgact
    61501 cacggagcct ttggggctat tgcctttggg attggtactt ctgaagtgga gcacgttctc
    61561 gctacccaga ccatttggca ggtcaaacct aagcgactcc tagtagagtt tgtcggtcag
    61621 gcgcaaagag gtgtctatgc caaggacttt atcctggctc tgattgcccg ctacggcgta
    61681 gattgtggtt tgggtcatgt ggtcgagttc gcaggacccg tcatcgaccg actcagcatg
    61741 gaagagcgga tgaccatctg caatatgtcc attgagttcg gctccaaaat gggcatcatg
    61801 gctccagacc agaccacctt tgactacctg cgaggtcggg agtgtgcacc agcggacttc
    61861 gatgcggcgg tggcagactg gaaggagctc tactcggatg cggacaccgt ctatgacaag
    61921 cacctggtcc ttgatgtgtc ggacttggca cccatggtga cttgggggac cactcctgct
    61981 atgggggtta gctttgacga aactttccca tccatccgtg accacaacga cgagcgggtc
    62041 tatgcttaca tggacttggc tcctgggcaa aaggctgcgg acattcccgt tggctatgtc
    62101 ttcctaggct cctgtactaa tgctcgcctc agcgatttgc agctggcagc taggattgtt
    62161 aaggggcgga aaatagcaga gcaggttacg gctattgtcg taccaggcag tcgccctgtc
    62221 aagcgtgctg cagaaaagtt aggtctagac aaggtccctg cgggtgtcca ctgcgcctct
    62281 acaagtaatc gaaactttga agaccgacag ggctttgggg ccaagaccca cttgtgtagt
    62341 cctgctatgg ctgccacagc tgcgctttat ggacgttttg tcgacaccag acagctagac
    62401 attctcaagg cgggagtcta atgcaccaat ttaccacatg gacagggaca accgttccac
    62461 tcatgaatga taatattgat accgaccagc tcctgcccaa gcagtttctc aagctgattg
    62521 acaaaaaggg ctttggcaag tatttgctat atgcttggcg gtacttggat gataactaca
    62581 cggacaatcc tgatttcatt ctcaatcagc ctgagtatca aggcgctagt atcctcatat
    62641 ctggggataa cttcggagca ggttcttcta gggaacacgc tgcttgggct ctggcagatt
    62701 atggcttcaa ggtcatcatt gcaggctcct ttggagatat tcattacaac aatgacttga
    62761 acaatgggat tctgcccatt atccagccca aagaagtcag ggaccaacta gctcagctgg
    62821 gtcctgacca agaaatcacg gttgacttgg cagatcagtt gatacggacg ccttttgggg
    62881 aatgcccatt tgacatcgaa caggactgga aacacaagtt gctcaatggc ttggatgata
    62941 ttggtattac cttacagtat caggatttga ttgctgagta tgaggataat cgcccaagct
    63001 actggcaaaa ctaaaaatat tagaaaacaa gcagatcgct ctgctatgga acaaaagaaa
    63061 agaggaaatt attatgacga aacaaattca ctgggatggc ggactttcac aagaaggttt
    63121 tgacattatc aagggtgagg gaggcgtgat tgtctgcccg accaaggttg gttacatcat
    63181 catgactgct gacaaggctg gcttggagcg taagtttgat gctaaggagc gcaagcggaa
    63241 taagccaggc gttgtccttt gtggtagcat ggaggagctt cgtgagttgg cacagttgac
    63301 tcctgagatt gatgccttct accaaaaaca ttgggatgag gacattttgt tgggttgtat
    63361 cctgccgtgg aaaccagagg cttatgctaa gttgcaggct tatggcgatg gtcgtgaaga
    63421 gttgatgacc gacgttcgtg gtacttcttg ctttgttatc aagtttggtg tagcaggcga
    63481 gcagattgct aaggaaatgt gggaaaaaga aggccgtatg gtctatgcgt catctgctaa
    63541 cccgtcaggt aagggaaatc gtggcaaggt agaaggtatc ggtgagcgta tcgcttctaa
    63601 agtggacttg attatcgagg cggatgatta tgtgacatct atccagccag acaagaccat
    63661 tgaaacccgc tatgagcaag gggttatggt gtctatggta gacaaagatg gtaaactcat
    63721 tccagaacaa agcgcggata gccgttctat cagcccatgt ccagttgtca tccgtaaggg
    63781 tctggacatt gataaaatca tgatgcactt gtctgaccat ttcaactctt gggactacag
    63841 acaaggggaa tattactaag atatcgtcat ttagtttatc ttttattacg tcgttaactc
    63901 accttgccta actccagtta tgcctgcggc tcgttgccta gtactaaaag taaactaaaa
    63961 gactattatt gagatcgatc cgaaagggtc gttttttcgt actcacataa aaaactgacc
    64021 gaaaattttt cagtcagttt cttatgttta ttcaattacc aacatgcctt ctttaacggc
    64081 aaatgggtgt tctgggtcaa tgcggtcgta gaacatgaca ccgttgaggt ggtcgatttc
    64141 gtgttggacc acgatggcat taaagccttt gagtttgata cggtgttttt ctccgttttt
    64201 gtccatgtaa tcaacagtca cgcgcgcatg gcggactacg tagccttgga cttcgcggtc
    64261 aacggatagg cagccctcgc ccccttccat agcagcttct tggacagaat gtgccacgat
    64321 tttaggattg tacaatactt cttgcagaga gtaggcttgg gcaggtggat ttccttcctc
    64381 gtcctctggg tttgggacta agacagcaat gatgcgtttg gaaacgtcaa tctgaggtgc
    64441 agctagacca actccgccac ggagtttcat tttttcagcc atgacaggat cctgcgaatg
    64501 tttgaggaac tgcatcattt tttcgcctaa aataatttcc tgatcagata gtggaaatgc
    64561 aacttcttcg gcaacttggc gtagggttgg atgcccttca cggatgatgt catccatgtc
    64621 aatcaaatgg gcagcttttg tcaatcgttc aataacagac atgattctct cctttgaata
    64681 tagttaagat aagtatagca tgaaatggga gagaataaaa gtcggacttt tctatccatt
    64741 cgctttcaaa tctgttatac tagtaaaaga cgaacgttga aagggagaaa aatgaaaaga
    64801 attttagaaa aagccagttt gctggcccta tccaccatgc tggtttcgac atttgctgtc
    64861 tcgccagcta ttccacagat gattgagtat tttgcccagc agggaattgc agcggcccag
    64921 gtggaaaact taattacggt gacctctttt gctattatgg ttactctatt ggcaaacggt
    64981 ctagttgtcc gtttcttgtc tgaacgaaac attatcattg cagggctttt gcttatggcc
    65041 atcggcggag ctttgcccat gtttctaact gcttatcctc tgattttatt ggctcgcatc
    65101 ttgcttggtt tggggattgg cctaatcaat gcgcgtgcta ttaatatcat cggtaatttt
    65161 ttcaccggtc aggagcgggt gcagatgatg ggcttgcgtg gttcagcaga ggttttggga
    65221 agtgcagggc ttaccctact tgtcggttgg ttgacccagt ttggttggca acctgccttc
    65281 ttggtctacc tttttgcctt ggtcatcttg gctctcttcc ttattttcgt acccaaggag
    65341 gaattgctgt ctcgcatgga ggtaaaggtt gaggagaacg cgcccaaggt caaactggac
    65401 aagaccatgt ggatgatggg catttatctg gcattcttag ccttctttgt tatcaatgtc
    65461 aataccttcc tgaccattcg tattcctcag attgttttag ccaagggcat cggtactgct
    65521 cagcaagcca gtctcattct aagtcttatg caggtcatgg ggattgtggc agggacggtc
    65581 tttagtagct tggttggtcg tttgaagggc tggcttttag ctgtttccta cgtggtcttt
    65641 ggactcgcgg ttgtcggcat tgcctttgca gataatctct gggtgctggg actcggtggc
    65701 atggtgtcag gatttttcta cagcatcatt ctaaccattg tctttagtca ggtaacagac
    65761 cgtgcaccca aggccttgct caatgcggtc atgacaatcg tccttatggg ctgcaatatc
    65821 ggcggtgcga catctgctat cttgccgact tatctggaaa aactcaaccc aaccccaaca
    65881 ggtgcctttg gtatttacgc catcggctgt gccttgataa gcgcaggctt gatttataaa
    65941 caactgaaga agtgggagtg agaaagaact cgactggtct aaaaagagtt cgtcaacaag
    66001 tccttatttc cagttgttga gctgaaacag tctatcccca gactgtttca ctcccacccc
    66061 cgcacagctc aaactgtctg ggagacagtt tgaggttgga gatgaagcga actctgttcg
    66121 catcagtcgt ataggtcaga tttggagtgt aatacacgaa caaatctgcc aatcaaccac
    66181 tgcgctgaga tgttgacacg aactctaagt agtagccgtt gggctttttg cccagcctct
    66241 tttggtataa tattcttatg ttagaaaata accgcttaaa tgaattaata ctccgttttc
    66301 cagaggatgt tcagttgatt tttaaggaca tgattccctc ctatcagttg ggctatgtgg
    66361 attatgttta tcagacagat agttacgcca cccaaaaccg tcggattaaa aatttagcaa
    66421 aaaatttctg aagaatggat tatttttaca tcatgcccct gccccaggat ctggcattgg
    66481 aaattgctaa ccaatggcgc tatcaaccac ctttggatgc ctatacgatt agtgcaaacc
    66541 ccgagattta tgctgtgatg atttcaccag aggcgcgtgg ggaccgcttt tttgcagtca
    66601 tccgcaatgc tgccctcatg ggctatttct gtattgacca agatggcgag acagttgaca
    66661 ttcgtttggg catgaaacct tctttgacag gtcagggaaa tggcagagct ttctaccagg
    66721 ctattgaaga ctatttagta gagcatgttc agccagctag tatcaaactg acagttgcta
    66781 gctctcatca agttgcccaa aaactctttc atgctcttgg ttttacagaa atagaaaagc
    66841 aagcagaata tatcaaaatg gaaaagaaac tcgtatgcga ttagataaat ttttagtgga
    66901 ttgcggtgtt ggcagtcgga cagaagtcaa gaaactcctg aaaaacaagc aagtcacagt
    66961 caacggccaa gtagaaacat cacccaaaca gcaaattaac gaaaaaaaag accagattgc
    67021 agtagcaggt caggtcctta gtcatgaaac ctttgtttac tatctgttaa acaagcctaa
    67081 gggagttatt tcagccaccg aggatgacca ccatcggact gtcttggacc tgctagataa
    67141 tacagctcgc cagaaggaag tttttcctgt tggacgcttg gacatcgata cccacggtct
    67201 cttgcttttg accaacaagg gtcagctggc tcatgccatg ctttctccga aaaagcatgt
    67261 tgataaactc taccgagcac aggttgacgg gatcatgacc caagaggatg tcgaacgatt
    67321 tgcggcagga attgagctga aagactttac ctgtcaacca gcccagttga ccatcctctc
    67381 tacagatgaa gctaagcaga cctcgctcgt tgacatcacc atccgagaag ggaaatttca
    67441 ccagatcaaa cgcatggtgc aggcttgtgg aaagacggtg acagacttgc aacgattgac
    67501 catggggcct cttcgcttag atccaaaatt agcgcttgga gaataccgca ggttgactgc
    67561 tgccgaatta aagcaattag aagtctttgg tgtggaatta tagataaata gaagagactt
    67621 gctcccgatt ggaggtcttc ttctttttgg ggtaagtaaa aaatgctaag ggtgtacagt
    67681 tgtcgtacct gaaattctag cccctacttg accgtacttg gcataacata ttacaatata
    67741 tacaagaacc tgtgttcaca gttcatagct tccattggag tgtttgaagg tggagataag
    67801 gaaaggagat tcctgaccaa ttaggtggta ggcgaaaaca gccacaggag ctttttactc
    67861 gtcgaagcaa taaagtgaaa ctaaatggtg atagagtcaa gtattccttc aaaaaattgc
    67921 cttgatgagc aaaaacgata tcttgcataa gaacactttg tttatgaata taggttctaa
    67981 gaattgtcca agagaggtta ttatatgttg aaatatatcc gtgcccttcc ccttgttata
    68041 gtagcgggag cggttgttta ctttactatt tttatctgta ttgataatgg tgattggacc
    68101 tatgttgtga ctagagcgct agggcttaag gaagaacatg ccaataatgt ttctttgatt
    68161 gtaattggtg cccaatcact ttttctaact tcggattggt tttacaagcg gattcgtgcc
    68221 tttctcaatc gtcgtttgga aaaggccaaa gggcttaatc ggcagattta tctgggctat
    68281 aaggcaggga ttgagttttt gatggcgtta cccaaacgaa ctattttatt cacattctat
    68341 ctacttttag tagttgctga aagtgttggt ctgattgaaa aagccaagga ctatgctgcg
    68401 gtaatcatct tcataattgc tgttgaccgc gtgaccaaaa tctggccgga ggaaaagggg
    68461 aggatgattg agtttagcca gaagattaag aaacggatta agagtgtgga gtagggagag
    68521 taatacctaa atatgta
//
LOCUS       DBNFCO010000003        54970 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.003, whole genome shotgun sequence.
ACCESSION   DBNFCO010000003 DBNFCO010000000
VERSION     DBNFCO010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 54970)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54970)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54970
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.003"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(5..577)
                     /locus_tag="AC1PIV_000145"
     CDS             complement(5..577)
                     /locus_tag="AC1PIV_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611205.1"
                     /translation="MEIFWCFYLISANIDDRMCISNTTKLIIGVKMRSHLGVRLSYEA
                     KYWLESIQAVIQEKLDAKINEQDIENLEHATKSYLKEVDNELGATSVTLILKASASSV
                     LEEAFEKTKSLSLKDWHKLDNEMKHSISSIPKDKDVGTLSVRFFLENSIITSLESYQK
                     EFMTSEMVRQVRLSYVLKLVIFAYYKEIMQ"
     gene            854..1636
                     /locus_tag="AC1PIV_000146"
     CDS             854..1636
                     /locus_tag="AC1PIV_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012774903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2971 domain-containing protein"
                     /protein_id="HIP6611206.1"
                     /translation="MKTLYHYTTVETLLLILNYKTLRFKSLLYVDDPLEPSTSDFGNL
                     GGFKYVSCWTDTPNSIPQWTMYSDNMTGVCIGISFDKETDVFLTEKFSLSESSEPIDM
                     VNALHPLKSGLLVTNNKYVPSLEQIRYTDDVSLITPRVVSSDDKSTTINLASNGIYKT
                     TDWSFQNEQRFSFQIFPLPIDLVLELMNANKGDLTEIINSFISVKPKEYFDLDLNPTI
                     FSNMTITFGKRCSAEDKLKVSKFLEDNKFHIPLFDSTVNIKP"
     gene            complement(1633..1902)
                     /locus_tag="AC1PIV_000147"
                     /pseudo
     CDS             complement(1633..1902)
                     /locus_tag="AC1PIV_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377895.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            1904..2002
                     /locus_tag="AC1PIV_000148"
                     /pseudo
     CDS             1904..2002
                     /locus_tag="AC1PIV_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226747.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
     gene            complement(2011..2148)
                     /locus_tag="AC1PIV_000149"
                     /pseudo
     CDS             complement(2011..2148)
                     /locus_tag="AC1PIV_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377895.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            2357..2800
                     /locus_tag="AC1PIV_000150"
     CDS             2357..2800
                     /locus_tag="AC1PIV_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent MarR family transcriptional
                     regulator"
                     /protein_id="HIP6611207.1"
                     /translation="MNRIALEIEKYLHEIVLSSENQLEILVGSCQSTVKLTNTQEHIL
                     MLIEKAAYTNTEIAKELNVSQAAITKATKSLVAQGLLVAVRDDKDARIVRFSLTEAAK
                     PIAAEHAHHHAHTLEAYEELLENYSLEEQESIARFLSELVEKIRK"
     gene            2801..3505
                     /locus_tag="AC1PIV_000151"
     CDS             2801..3505
                     /locus_tag="AC1PIV_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HIP6611208.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHIHYYLDSGEFVTLTGENGAAKTT
                     LIKATLGILKPKQGKVSIAEKSIKGKKLRMAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RQGWFRRLTAHDEEHVRISLESVGMWEHRDKRLGALSGGQKQRAVIARMFASDPDIFI
                     LDEPTTGMDAGTKDAFYQLMHHSAKKHGKSVLMITHDPDELNKYADRNIHLVRDQQSP
                     WRCFNVHEADEEVAHV"
     gene            3498..4310
                     /locus_tag="AC1PIV_000152"
     CDS             3498..4310
                     /locus_tag="AC1PIV_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HIP6611209.1"
                     /translation="MFDLSVFHYDFMQRAFLAIIAMSLFSPILGVFLILRRQSLMSDT
                     LSHVSLAGVAFGLVLGISPTLSTVLVVIVAAVFLEYLRTIYKNFMEIGTAILMSTGLA
                     ISLIVMNKSGGKSGLSLEQYLFGSIVTISQEQVIALFTIAVIVIVLTLLFLRPMYILT
                     FDEDTAFVDGLPVRAMSIAFNVVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKSF
                     KAVIFTGMGIGFFGMVMGLLTSYYAETPASASITLIFISIFLLVNVVQKFKK"
     gene            4320..5831
                     /locus_tag="AC1PIV_000153"
     CDS             4320..5831
                     /locus_tag="AC1PIV_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter solute-binding protein,
                     Zn/Mn family"
                     /protein_id="HIP6611210.1"
                     /translation="MKKVGLLFLSVSALLLGACGNSTASEDGKLNIVTTFYPVYEFTK
                     QVAGDEANVDLLVKAGTEVHGYEPSAKDIARIQEADAFVYENENMETWVHDVEKSLDT
                     TKVNVISATEGMLLLPGGEEEHEGHDHSEEGHSHAYDPHVWLSPERAITLVENIRDSL
                     VAKYPEKKDAFETNAAAYIEKLDALDAKYSETLSAAKQKYFVTQHTAFAYLALDYGLK
                     QVSITGVAADEDPTPSRLAELTEYINKYGIKYIYFEENASKSVAETLAKETGVQLDVL
                     NPLESLTDEDMKNGKDYISVMEDNLIALEKTTSQEGSEILPEEGAETAQTVYNGYFED
                     SAVKDRTLSDYAGEWQSVYPYLLDGTLDQVWDYKAKIKGGMTAEEYKTYYDTGYKTDV
                     DQINITDNTMEFVVGDKKEKFTYKYVGYKILTYKKGNRGVRFLFEATDANAGNYKYVQ
                     FSDHNIAPVKTGHFHIYFGGESQEKLLEELENWPTYYPVGLTGLEIGQEMLAH"
     gene            5934..6404
                     /locus_tag="AC1PIV_000154"
     CDS             5934..6404
                     /locus_tag="AC1PIV_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006825 - copper ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HIP6611211.1"
                     /translation="MEQTISAAEWQVMRVLWAHPGATSQEIIQALQEGFDWQATTIKT
                     LLGRLRKKNYLRMAKETSKYHYYPLISEEEHLQGQVELLLAAICSTKQGQLVEKLLDT
                     GTFSKKSLENLASKISQLQRTAPEQIACRCLAGQCTCGHHHTLRKSTSDVVDLT"
     gene            6585..6794
                     /locus_tag="AC1PIV_000155"
     CDS             6585..6794
                     /locus_tag="AC1PIV_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HIP6611212.1"
                     /translation="MKQTLKLKNLSCQNCVKHVTNHLLDLDGVEEVKIQLEEQLAEVA
                     TSVAYDLERYQEVLEDTIYEVEELV"
     gene            complement(6822..7199)
                     /locus_tag="AC1PIV_000156"
     CDS             complement(6822..7199)
                     /locus_tag="AC1PIV_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HIP6611213.1"
                     /translation="MTCIFCHQIEEIDILYQTEYFKVVWDIDPIQTGHLLIISKDHYD
                     TLSQVPPTIRYELSDLEVFLTEKLCQTLAIDGVTTACNDRLFNAGTHFHVHLIPRFRS
                     DGFWDQISLAQAQLDLTHFLKAL"
     gene            complement(7257..8513)
                     /gene="tyrS"
                     /locus_tag="AC1PIV_000157"
     CDS             complement(7257..8513)
                     /gene="tyrS"
                     /locus_tag="AC1PIV_000157"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HIP6611214.1"
                     /translation="MNIFEELKARGLVFQTTDEEALVKALTEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVTKIQ
                     GQLSRFLDFENGDNKAEMVNNYDWFSDISFIDFLRDVGKYYTVNYMMSKDSVKKRIET
                     GISYTEFAYQIMQGYDFYELNDKHNVTLQIGGSDQWGNMTAGTELLRRKADKSGHVMT
                     VPLITDSTGKKFGKSEGNAVWLDADKTSPYEMYQFWLNVMDDDAVRFLKIFTFLSLDE
                     IAEIEKQFDAARHERLAQKILAKEVVTLVHGEEAYNQALNITEQLFAGNIKNLSAKEL
                     KQGLSNVPNYAVQAEDNLNIVELLVTSGIVNSKRQAREDVQNGAIYVNGERVQDLDYT
                     LSDSDKIDGELTVIRRGKKKYSVLTY"
     gene            8667..11090
                     /gene="pbp1b"
                     /locus_tag="AC1PIV_000158"
     CDS             8667..11090
                     /gene="pbp1b"
                     /locus_tag="AC1PIV_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP1B"
                     /protein_id="HIP6611215.1"
                     /translation="MATKSDKQDFKKKISALGLGDVVGVFLRTLKLLFNSVAVLVFLF
                     GLFGAGIGIGFVVSLFDDVKIPKTEELVAKVSEVSRISTVTYSDGSLVSEVNSDLLRV
                     PITSEEVSNYLKQAVIATEDETFETHNGVVPKAVLRAALGSVGLGSSSGGSTLTQQLI
                     KQQLVGDAPTFTRKANEIVSALALERNMTKEEILTIYLNVSPFGRNNQGRNIAGVEAA
                     AQGIFGKPAKDLTVPQAAFIAGLPQSPIVYSPYASDGTRKSDEDMVYGIERYQDVLFN
                     MYRASFLTKEEYETYKAYDIKQDFIAPAPVMADTKDYLYYKVMEEAQEVMFDYLVKRD
                     KVSKNDLKNDETKASYEELAKQELSQGGYTIKSTVDQKIYAAMQSVVANYGSVLDDGN
                     EYVETGSVLIDNATGAILGFVGGRDYATNQNNHAFDTLRSPASTIKPLLAYGIAIDQG
                     LIGSASILSDYPTNFSSGQPIMYGSGRGTGMMNLQTAIDRSVNIPAFWTYKMMRNAGV
                     DAKAYMDKMNYHIPMYDIESVPLGGGVEISVLTNTNAYQTLANGGVYNKHYIVESITA
                     SDGTVVYQHEATPVQVYSKATASIMNQLLRQVVNSGYTTTFKSRLSGLNPQAASSDFV
                     GKTGTSNEVNDVWLMLSTPRVTLGTWAGNDDNSEMYVWTGYHNNSQYVAHMVDALYNV
                     NADMFAGKFELDSSVIASSVVASTGQRAGTTQVNGRQVTVGGAMTTSYWAKNGAPVTS
                     YNFMVGGTDSDRAQAWNTIIGSQTATSSSSTQRSSSTRSSTSSSANNTNQSSETQTAT
                     SEQANNDSP"
     gene            11536..15108
                     /gene="rpoB"
                     /locus_tag="AC1PIV_000159"
     CDS             11536..15108
                     /gene="rpoB"
                     /locus_tag="AC1PIV_000159"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed RNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HIP6611216.1"
                     /translation="MAGHEVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFQDFLDYG
                     LKEVFEDVLPVSNFTDTMELEFVGYELKEPKYTLEEARAHDANYSAPIYVTFRLVNKE
                     TGEIKTQEVFFGEFPIMTEMGTFIINGAERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELETDSKDIAYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTIEKDIHKNPADSRTDEALKEIYERLRPGEPKTAESSRSLLTARFFDPRRYDLAPVG
                     RYKINKKLNLRTRLLNQTLAEHVINGETGEIVLEAGTVLSRDVLEKVEAQFDELNLVE
                     YIPNDNAVLLEPVLLQKFKIVAPKDPERVVTVIGNANPAENVRTVTPADILAEMSYFL
                     NLAEGLGRVDDIDHLGNRRIRAVGELLANQVRIGLTRMERNLRERMSVQDNEVLTPQQ
                     IINIRPVTAAIKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVRD
                     VHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFIQTPYRKIDRATGTVTNEIVW
                     LTADEEDAYIVAQSTSPLDENNRFVDKIVMGRHQGNNQEFPADSADFMDVSPKQVVAV
                     ATACIPFLENDDSNRALMGANMQRQAVPLIDPKAPYVGTGMEYQAAHDSGAAIIAQHD
                     GKVVYADADKVEVRREDGSLDVYHISKFRRSNSGTAYNQRTLVKLGDIVEKGDFIADG
                     PSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDTK
                     LGPEEITREIPNVGEDALRNLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERLL
                     HAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRANGDELQSGVNMLVRVYIAQKRKI
                     KVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHLG
                     MAARNLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGVM
                     YMIKLHHMVDDKLHARSVGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVLQ
                     EILTYKSDDVTGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDNNE
                     VELRDLDEGEDDDIIHVDDLEKARAKAAADAAAAFAAEEAEGKE"
     gene            15286..18933
                     /gene="rpoC"
                     /locus_tag="AC1PIV_000160"
     CDS             15286..18933
                     /gene="rpoC"
                     /locus_tag="AC1PIV_000160"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012774906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed RNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HIP6611217.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERD
                     GLFDEVIFGPTKDWECSCGKYKRIRYKGITCDRCGVEVTRAKVRRERMGHIELKAPIS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLPKEIAALKEELKTASGQKRIKAVRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMVQLDGGRFAASDLNELYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIAGNVKAAKRLIE
                     RGDDRIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEDA
                     GREGEGMVFKDADEAVMAYRNGYVHLHTRVGIATDSLDKPWKDNQKHKVMMTTVGKIL
                     FNAIMPEGLPYLQEPNNANLTEGTPDKYFLEPGSDIKAAIAELPINPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRLKDLGYYHSTLAGLTVGIADIPVIDNKAEIIEESHERVEQ
                     IKKQFRRGMITDDERYAAVTDEWRSAKEKLEKRLVEKQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMSAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLDIRSITDGKEMIEPLEERLQGRYTKKTVKHPE
                     TGAVIIGPNQLITEDIAREIVNAGVEQVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNSDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGEVIAIEEDASTRTKKVFVKGKTGEGEYVVPFTARMKVEVGDQVARGAALTEGS
                     IQPKRLLEVRDVLAVETYLLSEVQKVYRSQGVEIGDKHIEVMVRQMLRKVRVMDPGDT
                     DLLMGTLMDITDFTDANAEVVIAGGIPATARPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKRDNLLGLKENVIIGKIIPAGTGMARYRNLEPQAINEVEIIEDTVAEEL
                     AAEAELEAVTE"
     gene            19083..19448
                     /locus_tag="AC1PIV_000161"
     CDS             19083..19448
                     /locus_tag="AC1PIV_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HIP6611218.1"
                     /translation="MYQVIKMYGDFEPWWFLDGWEEDVTSRAAFDRYEDALNAFQKEW
                     VRLSEDFPMKKSKNGTMVAFWDESDQHWCEECDEYLQRYHSLMLVEARENLPAGFIKQ
                     PTQPRVRPCKLKQNNCVNE"
     gene            complement(19483..20426)
                     /locus_tag="AC1PIV_000162"
                     /pseudo
     CDS             complement(19483..20426)
                     /locus_tag="AC1PIV_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936565.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="S66 family peptidase"
     gene            20512..21462
                     /gene="comGA"
                     /locus_tag="AC1PIV_000163"
     CDS             20512..21462
                     /gene="comGA"
                     /locus_tag="AC1PIV_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus ATPase ComGA"
                     /protein_id="HIP6611219.1"
                     /translation="MIQEKARKMIEEAVADRVSDIYLVPRGECYQVYHRIMDDREFVQ
                     DLAEEEVTAIISHFKFLAGLNVGEKRRSQQGSCDYDYGSGEISLRLSTVGDYRGKESL
                     VIRLLYDNDKELKFWFEAAERLAEEIKGRGLYLFSGPVGSGKTTLMYHLARLKFPDKQ
                     ILTIEDPVEIKQEDMLQLQLNEAIGATYDNLIKLSLRHRPDLLIIGEIRDAETARAVI
                     RASLTGATVFSTVHARSISGVYARMLELGVGPEELNNALQGIAYQRLIGGGGVVDFAK
                     GNYQNHSADQWNAQIDRLFAAGHISLRQAETEKITLGSPA"
     gene            21374..22411
                     /gene="comGB"
                     /locus_tag="AC1PIV_000164"
     CDS             21374..22411
                     /gene="comGB"
                     /locus_tag="AC1PIV_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus assembly protein ComGB"
                     /protein_id="HIP6611220.1"
                     /translation="MRKLIGFLQQDISVFGRQKQKKLPLARQRKVIELFNNLFASGFH
                     LGEIVDFLKRSQLLADPYTQVLSDGLLAGKPFSSLLADLRFSDAVVTQVALAEVHGNT
                     SLSLIHIQSYLENVSKVRKKLIEVATYPIILLGFLLLIMLGLKNYLLPQLEEGNAATV
                     LINHLPTIFLSLSGLSLVAVLAGMVWFRKTNKIKVFSCLAALPFFGKLIQTYLTAYYA
                     REWGSLIGQGLDLPQIVGLMQEQQSQLFREIGQDLEQSLSNGQSFHEHIKTYAFFKRE
                     LSLIVEYGQVKSKLGSELTVYAAECWEDFFSRVNRAMQLIQPLVFLFVALMVVLIYAA
                     MLLPIYQNMEL"
     gene            22413..22694
                     /gene="comGC"
                     /locus_tag="AC1PIV_000165"
     CDS             22413..22694
                     /gene="comGC"
                     /locus_tag="AC1PIV_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030420 - establishment of competence for
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus major pilin ComGC"
                     /protein_id="HIP6611221.1"
                     /translation="MKKLVEMKVKGFTLVEMLVVLGIISLLLLLFVPNLSQQKDAIQK
                     KGDAAVVKVVESQMELYELEHDEEATVADLQAKGYITEKQAKQYATAKK"
     gene            22675..23082
                     /gene="comGD"
                     /locus_tag="AC1PIV_000166"
     CDS             22675..23082
                     /gene="comGD"
                     /locus_tag="AC1PIV_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGD"
                     /protein_id="HIP6611222.1"
                     /translation="MLRRKNKAFTLFESLLTLLVVSFLAVSLSGTVQTVFRSVQEEIF
                     LWEFEAIYKDSQKLAASSHKKVNLAIGGQEVTNGYQAVEVPRNVEVLEEKTIQFEEDG
                     GNSSLTKIRFHLSQKIVTYQLYIGSGRYKKTEE"
     gene            23054..23347
                     /gene="comGE"
                     /locus_tag="AC1PIV_000167"
     CDS             23054..23347
                     /gene="comGE"
                     /locus_tag="AC1PIV_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002282213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGE"
                     /protein_id="HIP6611223.1"
                     /translation="MVAIRKQKNKAYILLESLVALATLVTICSLILSAVDAGRRRQVW
                     ELEQQEVFNLAQMAVQTKQDDLALNGVAVQVQRTAERVAVFHEGKEVLSVVKK"
     gene            23334..23768
                     /gene="comGF"
                     /locus_tag="AC1PIV_000168"
     CDS             23334..23768
                     /gene="comGF"
                     /locus_tag="AC1PIV_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGF"
                     /protein_id="HIP6611224.1"
                     /translation="MLKSKIPAFTLLECLVVLVILSGSLLIFEGLSKLLVQEAHYQGQ
                     TVQKEWLVFSSQLRSEWDQAELVKVENGKVYVNKGEQALAFGKSWSDDFRKTNDRGQG
                     YQPMLYQVDSAAISQENQLVRIDFSFKNGEERTFIYAFKEKS"
     gene            23746..24156
                     /gene="comGG"
                     /locus_tag="AC1PIV_000169"
     CDS             23746..24156
                     /gene="comGG"
                     /locus_tag="AC1PIV_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009909099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGG"
                     /protein_id="HIP6611225.1"
                     /translation="MLLKKKVKAGILLYALLMLAVFSLLLQFYLHRQEAESRLVQVAR
                     QETTAYIMAQMVLDKVEQDLQVEKIVTGAVVNEKEANLTTGSKQKENRGRVSFQEGQA
                     RYQLKGDQLLVTVELTSDGLYTYQFPFGLSSEGG"
     gene            24213..25166
                     /locus_tag="AC1PIV_000170"
     CDS             24213..25166
                     /locus_tag="AC1PIV_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HIP6611226.1"
                     /translation="MNFEKIEQAYDLLLENVQTIQNQLGTNIYDAMIEQNATYVAGQH
                     ETDLVVKNNQTLKQLDLTKEEWRRAYQFLLIKANQTEPMQYNHQFTPDSIGFILSFLV
                     DQLVPTQKVTVLEIGSGTGNLAQTILNASQKELDYLGIEVDDLLIDLSASIADVMQAD
                     ISFAQGDAVRPQILKESQVILGDLPIGYYPDDQIASRYQVASPKEHTYAHHLLMEQSL
                     KYLEKDGFAILLAPNDLLTSPQSDLLKGWLQEQANIVAMIALPPNLFGKTAMAKSIFV
                     LQKKAARSLTPFVYPLQSLQEPEAIQKFMLNFKNWKQENAI"
     gene            25216..26403
                     /locus_tag="AC1PIV_000171"
     CDS             25216..26403
                     /locus_tag="AC1PIV_000171"
                     /EC_number="2.7.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008776 - acetate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006085 - acetyl-CoA biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HIP6611227.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVLAAGIIERIGLNDSISTV
                     KYDGKKESEVLDIPNHTVAVKILLEDLLKHNIIAAYEEITGIGHRVVAGGEYFKESAV
                     ISQQEIEQIEELSALAPLHNPAHVAAMRAFEEVLPEVLNVAVFDTAFHTTMPKHAYLY
                     PIPQKYYTDYKVRKYGAHGTSHYYVAHEAAKVLGRPIEELKLITAHIGNGVSITANYH
                     GESVDTSMGFTPLAGPMMGTRSGDIDPAIIPYLIANVEELKDAADVVNMLNKQSGLFG
                     VSGFSSDMRDIEAGIQAHNPDAVLAYNIFIDRIKKFIGQYLAVLNGADAIVFTAGMGE
                     NAPLMRNDVVEGLSWFGIELDLEKNVFGNYGDISTAESKVRVLVIPTDEELVIAREVE
                     RLK"
     regulatory      26529..26673
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF01831"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="THF riboswitches regulate genes encoding folate
                     transporters and folate metabolism; They are most commonly
                     found in Clostridiales and Lactobacillales; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="tetrahydrofolate"
                     /db_xref="RFAM:RF01831"
     gene            26718..27269
                     /locus_tag="AC1PIV_000172"
     CDS             26718..27269
                     /locus_tag="AC1PIV_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HIP6611228.1"
                     /translation="MEKKIPKLTVQLLAAIAMTLALVMIVENYFSIRISDTLQVQFTF
                     IPNTILGAIAGPVWAAVFAAISDPVFVLFSGQTVLFTWILIEAVSAFIYGWFFYRKPL
                     DTKNKADWLYVAGVVVLIQVVISFIMTPIALHFHFGTPWIVLYSSRLIKAVFEIPLRI
                     VVTMLVLPSLQKIPELAKLMGIK"
     gene            27325..28581
                     /locus_tag="AC1PIV_000173"
     CDS             27325..28581
                     /locus_tag="AC1PIV_000173"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HIP6611229.1"
                     /translation="MNYQETRRWLSSRPASDLENGVARVNWILERLDNPQLQVPTVHF
                     VGTNGKGSTLNALQSILQSSDYTVGRFTSPSIIDFREQIVYQQEMISEEDFARIVTDL
                     QPLIEDLDQTAGLDAISEFEIVVVAMFVYFAHYQRPDILLVEAGMGGLQDATNVLAPL
                     AVVCPSIGLDHQAFLGETHAAIARHKVAVLREGVPLIYATDQPEVETVFEEHACQLQS
                     PTYAVGREILLENSRAGFAVSSPLGRVEELTLQMQGRHQEVNAALAVTTAQLIKPHFP
                     TITNETIRQGLSQAIWPGRLELIRPNLMIDGAHNNESIAVLTQLLEEKYADRDIEILF
                     AAINTKPVDQMLSQLSQFGPVSVTTFDDFRAVQLEDYPSGYERVQTYQEWVEQADLDN
                     PKKLYLITGSLYFITYVRKYILEELV"
     gene            complement(28629..29690)
                     /gene="pepA"
                     /locus_tag="AC1PIV_000174"
     CDS             complement(28629..29690)
                     /gene="pepA"
                     /locus_tag="AC1PIV_000174"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HIP6611230.1"
                     /translation="MTLFGKIKEVTELQSLPGFEGQVRNHIRQKITPHVDRIETDGLG
                     GIFGIKDTAVENAPRILVVAHMDEVGFMISQIKPDGTFRVVELGGWNPLVVSSQAFTL
                     QLQDGRTIPAISGSVPPHLSRGANAPGMPAIADIIFDAGFANYDEAWAFGVRPGDVLV
                     PKNETILTANGKNVISKAWDNRFGVLMVTELLESLSGHALPNQLIAGANVQEEVGLRG
                     AHASTTKFNPDIFLAVDCSPAGDIYGDQGKIGDGTLLRFYDPGHIMLKNMKDFLLTTA
                     EEAGVKFQYYCGKGGTDAGAAHLKNHGVPSTTIGVCARYIHSHQTLYSMDDFLEAQAF
                     LQTIVKKLDRSTVDLIKNY"
     gene            30498..30782
                     /locus_tag="AC1PIV_000175"
     CDS             30498..30782
                     /locus_tag="AC1PIV_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HIP6611231.1"
                     /translation="MKKKKTALLAGLLGAGVLTASAQFYRKIQEDRKKAQALQEVRDF
                     FADLGEIATVYVDETASTQTTLIGGVVMEAGQVFLFENTKGSIQYREEER"
     gene            30779..31099
                     /locus_tag="AC1PIV_000176"
     CDS             30779..31099
                     /locus_tag="AC1PIV_000176"
                     /EC_number="1.8.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HIP6611232.1"
                     /translation="MIFPTNHEEVAALIEDGKPTVFLFVTTWCGDCHYIKPHVPAIEE
                     AFPDLRFVQLDRDDFMPLAQEWAILGIPSLVVLENGKEIGRFVDKNRKTKEEIMNFLS
                     GLGR"
     gene            31144..32100
                     /locus_tag="AC1PIV_000177"
     CDS             31144..32100
                     /locus_tag="AC1PIV_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HIP6611233.1"
                     /translation="MKKSLGKILLAPVVLGLSLSLAPLVQAEIQTDVINEKWGKPTLV
                     YGGGLSDAQATEVNNLFGISDVNNVSRQVVVGTDMDQYLGTSEADTASLYSSVLVQKQ
                     DAGKGVVVDIKTPQNITLITETQYANAAITAGATDVLIDVASPIQVTGESALTGVYKA
                     LAANGETVDTARTEVAQQELETVNEVATAHTGDTNFDSSALDKAVAEIKTALADYKKS
                     NGQVASEADINTIINDVLAQNGLENVITADEVSKLVTFAKAYQETSAIDSAEVAAQLN
                     QFKQQAEQQISEAYKNLQDSGILEKIGAFFENLWKGLTGLFA"
     gene            32119..32742
                     /gene="ytpR"
                     /locus_tag="AC1PIV_000178"
     CDS             32119..32742
                     /gene="ytpR"
                     /locus_tag="AC1PIV_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtpR family tRNA-binding protein"
                     /protein_id="HIP6611234.1"
                     /translation="MIFTYNKEHVGDVLMVIVAEDKGQAVQFERKGQVARVFLEETGK
                     TVAWNIFEASSLVELDGNGQVFLTDEQVATLNAELAKEGFTESLVNDNAPKFVVGQIV
                     ELVPHPDSDHLNICQVNVGDKTVQIVAGAPNAAQGLKTIVALPGAMMPSGSLIFPGKL
                     RGEDSFGMMCSPRELALPNAPQVRGIIELDDSAVVGEAFDPAKHWKG"
     gene            complement(32775..33554)
                     /locus_tag="AC1PIV_000179"
     CDS             complement(32775..33554)
                     /locus_tag="AC1PIV_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HIP6611235.1"
                     /translation="MKEFLMEKIQTSQPYTNAELDWLLENIGHPDPTIRDELVYASFC
                     HIFLEGLITREQAQSLLQFSQETKPFSLEGPTQKRSFTCLLYCLLLSVDNEPESIYHA
                     FLSTDDHELLFQQALDYLTIENDWSGYDEKLGWIHTAAHGADFLLATSCHDQFPAEKS
                     KEVWQTIVTCLTKQSKVFSAGEEIRLAQIPVYLLLNEKVSSQELTEWISKLDFPNQEP
                     VDYFRWLNLQHFLSSLYFQLKSQQASTEEIEQAIEGKIEPA"
     gene            33609..34004
                     /locus_tag="AC1PIV_000180"
     CDS             33609..34004
                     /locus_tag="AC1PIV_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HIP6611236.1"
                     /translation="MYNKTILIGRLTAQPELTQTPTGKNLTRVTVAVNRRFKTENGER
                     EADFLNVIFWGKLAETLVSYGSKGSLISIDGELRTRKYEKDGSNHYVTEILGQSFQLL
                     ESRAQRAMRENNTGDDLADLVLEEEELPF"
     gene            complement(34123..34368)
                     /locus_tag="AC1PIV_000181"
     CDS             complement(34123..34368)
                     /locus_tag="AC1PIV_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611237.1"
                     /translation="MKFFRDLKIDYLESRFSAYESFAEWFLKRKLGFLGKMIFAYLLW
                     LVWWLLFSHPHYIIFFFYGVLLLSLIIMLIEWWKYRK"
     gene            34566..34847
                     /gene="groES"
                     /locus_tag="AC1PIV_000182"
     CDS             34566..34847
                     /gene="groES"
                     /locus_tag="AC1PIV_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HIP6611238.1"
                     /translation="MLKPLGDRIAVKIEEKEQTVGGFVLAGASQEKTKEASVLAIGQG
                     IRTLNGDLVAPAVAVGDTVLIDAHAGLEVKDGDQNVHIIRETDILAIVE"
     gene            34858..36480
                     /gene="groL"
                     /locus_tag="AC1PIV_000183"
     CDS             34858..36480
                     /gene="groL"
                     /locus_tag="AC1PIV_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940029.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HIP6611239.1"
                     /translation="MAKEIKFAADARESMVRGVDILADTVKVTLGPKGRNVVLEKAYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPIGIRRGIEAAVATAVEALKAQASPVSNKAEIAQVAAVSSRSEKVGEYI
                     SEAMERVGTDGVITIEESRGMETELDVVEGMQFDRGYLSQYMVTDNEKMVAELENPFI
                     LITDKKISHIQDILPLLESILQANRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLDLKDATIEALGQAAKVVVDKDGATIVEGA
                     GNPEAIANRVAVIKSQIEVTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALVNVIDSVAKLELKGDDETGRNIVLRALEEPVRQ
                     IAYNAGYEGSVIIDKLKNSELGTGFNAATGEWVNMMDAGIIDPVKVTRSALQNAASVA
                     SLILTTEAVVANKPEPAAPAMPQGMDGMGMGY"
     gene            36712..37125
                     /gene="rpsL"
                     /locus_tag="AC1PIV_000184"
     CDS             36712..37125
                     /gene="rpsL"
                     /locus_tag="AC1PIV_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HIP6611240.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSRKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKG"
     gene            37142..37612
                     /gene="rpsG"
                     /locus_tag="AC1PIV_000185"
     CDS             37142..37612
                     /gene="rpsG"
                     /locus_tag="AC1PIV_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HIP6611241.1"
                     /translation="MSRKNQAPKREVLPDPLYNSKLVTRLINRVMLDGKRGTAASIVY
                     GAFDQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARNRGEHTMIDRLAKEIMDAANNTGAAVKKREDTHKMAEANRAFAHFRW"
     gene            38169..40250
                     /gene="fusA"
                     /locus_tag="AC1PIV_000186"
     CDS             38169..40250
                     /gene="fusA"
                     /locus_tag="AC1PIV_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HIP6611242.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHERLQANAH
                     PIQLPIGSEDEFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLEQAEEYREKLVEAV
                     AETDEELMMKYLEGEEITNDELKAAIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGVNPDTDAEEERHASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     NSGSYVLNTSKGKRERIGRILQMHANSRQEIETVYAGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESIHVPEPVIQLMVEPKSKADQDKMGIALSKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPIVDVKAKLY
                     DGSYHDVDSSETAFKVAASLALKEAAKSAQPTILEPMMLVTITAPEDNLGDVMGHVTA
                     RRGRVDGMEARGNTQIVRAYVPLAEMFGYATVLRSATQGRGTFMMVFDHYEDVPKSVQ
                     DEIIKKNGGNA"
     gene            41239..43230
                     /locus_tag="AC1PIV_000187"
     CDS             41239..43230
                     /locus_tag="AC1PIV_000187"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014917178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family metallopeptidase"
                     /protein_id="HIP6611243.1"
                     /translation="MRKKLKFSLVAVACATFLTACGTSNSSAPKAGEATPQTDFHSYI
                     NAQWLKNTKLGAGESQIDNLSQLSEKTQEAIQEMIDQLDMDYSKLQAGSDEKKLIDFY
                     RLAADFDTRNKLGLEPIKPYLEEIKKASTMEELNKILVALYGKNIRNLLHINVTQDIK
                     DSNKNTIYVDPHELSFPKENYDGTDEFSLKNQKAFKAYLQEVFSLSGETSKEASSKAD
                     LLFNLEKEMAAVQRPKEEANNFEAMYNEKTWDEVKALVPNLPIAELVSELGLQNAPTT
                     VVSDPDALKNLNELYQEKNLDALKALLQYRVIAHYNAYLSSNLIEAKAKYDGVATGAV
                     DTPSQKEVAQAAIDANFSDMIGKVYVKHHFSEESKANILSMVQEIKATYAERIKAVQW
                     MSEETKMRALKKLDTLVVKIGYPDQWKDYSQLAIQSKEEGGSLLSNFDMVKTLELREE
                     MGQFGKPFDKSQFGMPSHTVNAYYSPTNNEIVFPAGILQAPLYDPKASPEENLGGIGA
                     VIGHEISHAFDKAGSQFDEKGNLVNWWKPEDLEKFNKKVQQAADIYSKLEVAPGYYVN
                     GEISTGEIMADLGGLTVAIDIAQKKGYDTKKVFESYGKAWREVTTKEFAIANISDEHP
                     PAKYRVNNIVNQIDQFYTDFNVKEGDPMYVKPEDRLRVW"
     gene            43597..44607
                     /gene="gap"
                     /locus_tag="AC1PIV_000188"
     CDS             43597..44607
                     /gene="gap"
                     /locus_tag="AC1PIV_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HIP6611244.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKDGGFEVNGKFVKVSAEREPGNIDWATDGVDIVLEATGFFAS
                     KEKAEQHIHANGAKKVVVTAPGGNDVKTVVFNTNHDILDGTETVISGASCTTNCLAPM
                     AKALHDAFGVQKGLMTTIHGYTGDQMVLDGPHRGGDLRRARAAAANIVPNSTGAAKAI
                     GLVIPELNGKLDGAAQRVPVPTGSVTELVATLDKKVTAEEVNAAMKAAATESFGYTED
                     QLVSSDIVGISFGSLFDATQTKVIEVDGEQLVKVVSWYDNEMSYTAQLVRTLEYFAKI
                     AK"
     gene            44863..46062
                     /locus_tag="AC1PIV_000189"
     CDS             44863..46062
                     /locus_tag="AC1PIV_000189"
                     /EC_number="2.7.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HIP6611245.1"
                     /translation="MAKLTVKDVELKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYILEQGGRAILFSHLGRVKEEADKEGKSLAPVAADLAAKLGQDVAFIAGATRGAELE
                     AAINALEDGQVLLVENTRFEDVDGKKESKNDEELGKYWASLGDGIFVNDAFGTAHRSH
                     ASNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLE
                     KADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKTLLEKANGKLILPVDSKEANA
                     FAGYTEVRDTDGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQA
                     GTIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPG
                     LAALTEK"
     gene            46869..47384
                     /locus_tag="AC1PIV_000190"
     CDS             46869..47384
                     /locus_tag="AC1PIV_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HIP6611246.1"
                     /translation="MFKKYTFDPKKFRLGMRTFKSGLAVFLVILLFGFMGWQGIQIAA
                     LTAVFSLREDFDQSVHFGASRILGNSIGGFYALLFFILDRLFLDHFWVTAVFVPIFVM
                     LTIMTNVAMNNKAGIIGGVSALLIITLSIPAGDTIQYVFIRVFETFIGVFIAILVNYD
                     VNVIKKRFQDK"
     gene            47460..47831
                     /locus_tag="AC1PIV_000191"
     CDS             47460..47831
                     /locus_tag="AC1PIV_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HIP6611247.1"
                     /translation="MREKEFRRSLAIFPIGSVMKLTDLTARQIRYYEDQGLIKPDRNE
                     GNRRLYSLNDMDLLLEIKDFLDEGLNIAAIKKEYANREAKAKVQKQQKTLTDEDVRRI
                     LHDEFSRQGRFSSPSSIFRSS"
     gene            47860..49206
                     /gene="glnA"
                     /locus_tag="AC1PIV_000192"
     CDS             47860..49206
                     /gene="glnA"
                     /locus_tag="AC1PIV_000192"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamine synthetase activity
                     [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HIP6611248.1"
                     /translation="MTFTVADIKRDIKEKNVTFLRLMFTDIMGVMKNVEIPATDEQVE
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTIFPWGDENGRVAGLICDIYTTDA
                     KPFAGDPRGNLKKSLRHMEEAGFSSFNLGPEPEFFLFKMDEQGNPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTEMGFEVEASHHEVAVGQHEIDFKYADVLKACDNIQIFKLV
                     VKTIARKHGMYATFMAKPKFGIAGSGMHCNMSLFDKDGNNAFFDPEDPRGMQLSQTAY
                     HFLGGLIKHAYNYTAITNPTVNSYKRLVPGFEAPVYIAWAGKNRSPLVRVPASRGMGT
                     RLELRSVDPTANPYLAMAVLLEVGLEGIQNKIEAPAPVESNIYAMSDEERREAGITDL
                     PSTLHNALKALREDEVVRAALGDHIYTNFLEAKKIEWASYATYVSQWEIDNYLDMY"
     gene            complement(49429..51108)
                     /gene="rnjA"
                     /locus_tag="AC1PIV_000193"
     CDS             complement(49429..51108)
                     /gene="rnjA"
                     /locus_tag="AC1PIV_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J1"
                     /protein_id="HIP6611249.1"
                     /translation="MSSVNLKPHEVGVFAIGGLGEIGKNTYGIEYKDEILIVDAGIKF
                     PEDDLLGIDYVIPDYSYIVENLDRVKGLVITHGHEDHIGGIPFLLKQANVPIYAGPLA
                     LALIRGKLEEHGLLRDATLHEINHNTELTFKHLKVSFFRTTHSIPEPLGIVVDTPQGK
                     IVCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIM
                     KLIEGIHGRIIFASFASNIFRLQQAADAAVKTGRKIAVFGRSMEKAIVNGIELGYIKV
                     PKDTFIEPNEIKEYPASEIMILCTGSQGEPMAALSRIAHGTHRQVQLQPGDTVIFSSS
                     PIPGNTTGVNKLINILIEAGVDVIHGKINNIHTSGHGGQQEQKLMLRLIKPKYFMPVH
                     GEYRMQKIHASLAVDTGVPKDNIFIMENGDVLALTKDSARLAGQFNAQDIYVDGNRIG
                     EIGAAVLKDRRDLSEDGVVLAVATVDFNSKMILAGPDILSRGFIYMRESGELIRESQR
                     VLFNAIRIAMRNKDANIQTVNGAIVNALRPFLYEKTEREPIIIPMILTPDR"
     gene            complement(51112..51342)
                     /locus_tag="AC1PIV_000194"
     CDS             complement(51112..51342)
                     /locus_tag="AC1PIV_000194"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed RNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase subunit epsilon"
                     /protein_id="HIP6611250.1"
                     /translation="MIYKVFYQESKISPRREQTRALYLDIDAASELEGRIIARELVET
                     NRPEYNIEFIDLLSDNHLEYEKEHADFKITEF"
     gene            51949..52632
                     /gene="tsaB"
                     /locus_tag="AC1PIV_000195"
     CDS             51949..52632
                     /gene="tsaB"
                     /locus_tag="AC1PIV_000195"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HIP6611251.1"
                     /translation="MKILALDSSNQALSVALVEDGRLQAETLLAVKKNHSISLMPVVD
                     FLVAQVGWTPKDLDRIVVAQGPGSYTGLRVAVATAKTLAYTLKIDLVGLSSLQSLVPP
                     SLTGLVVPLIDARRNCVYAGVYENGRAVEPDRYWSFEDLLSSLSGKENITFVGEVENF
                     MEQIEQALPTAQYQASLPSAYQLAVIGQDLPAVDVTSFEPNYLKHVEAEENWLKDNQV
                     GSESYIKRV"
     gene            52629..53069
                     /gene="rimI"
                     /locus_tag="AC1PIV_000196"
     CDS             52629..53069
                     /gene="rimI"
                     /locus_tag="AC1PIV_000196"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 - protein-N-terminal-alanine
                     acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HIP6611252.1"
                     /translation="MIEIKHYDGQENLAEAVLAVMQSVYDQSPWTLEQIVSSMTSQYE
                     DYYLAYEGQELVGFLAVQTVLDEMEILQIAVKTDFQRLGIASQLMAAVMDWDGDIFLE
                     VRESNSAAQALYTRQHFTKIGKRKDYYRHPVEDAVIMKRERDER"
     gene            53059..54066
                     /gene="tsaD"
                     /locus_tag="AC1PIV_000197"
     CDS             53059..54066
                     /gene="tsaD"
                     /locus_tag="AC1PIV_000197"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HIP6611253.1"
                     /translation="MKDRLILAIETSCDETSVAVLRNDAELLSNVIASQIASHQRFGG
                     VVPEVASRHHVEVITACIEEALLEAEVTAEDLTAVAVTYGPGLVGALLVGISAAKAFA
                     WANGLPLIPVNHMAGHLMAARAVKELEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLPYPAGRVIDELAHEGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLYHNAQQKGETLSNADLSASFQACVMDILMAKTKKALEQYPVKTLVVAGGVAANQ
                     GLRERLAAEITDVEVIIPPLRLCGDNAGMIALAAVSEYNKENLAGWDLNAKPSLAFEN
                     L"
     gene            complement(54103..54939)
                     /locus_tag="AC1PIV_000198"
     CDS             complement(54103..54939)
                     /locus_tag="AC1PIV_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HIP6611254.1"
                     /translation="MKIQPEFYVFNNRSYVDFYPIQFGMEACKPLHSFGPTMKQHYLF
                     HYIISGSGTFYDTSDQREYHLTAGQGFLISPDAICSYEADEKDPWTYIWLEFDGLKTE
                     HFLRQAGLSKEQPIFSQREMPTSSPVYHEMKQILALHHQKSALVLGHLYLFISCLIDC
                     SLTKTSSKHDENKEFYIREAINFVERNYEKAISVDDLAQVCNLNRHYFSRLFKEQMNI
                     SPQQFIIQYRLSEACELLKNTTKTLQEIAEEIGYSNQFNFSTAFKRHYQISPNRWRKI
                     HK"
BASE COUNT        15728 a        10620 c        12976 g        15646 t
ORIGIN      
        1 tcctctactg cattatttct ttatagtaag caaaaataac aagttttaga acatatgaca
       61 atctaacttg cctaaccatt tcagaagtca taaattcttt ttgataactt tccaatgatg
      121 taataataga attttccaaa aaaaatctta cagacaaggt tccaacatcc ttatcctttg
      181 gaatagacga aatcgaatgt ttcatttcat tatctaattt atgccaatct ttcaaactta
      241 aagatttcgt tttttcaaaa gcctcttcta aaacacttga tgcagaggct tttaaaatca
      301 aagtcactga agttgcccct aattcattgt caacttcttt caaatatgat tttgttgcat
      361 gttctaaatt ttctatatct tgttcattta ttttagcgtc taacttttcc tgaatcactg
      421 cttgtattga ttctaaccaa tacttcgctt cgtaagatag acgtactcca aggtgtgagc
      481 gcatttttac tcctattatt agttttgttg tatttgatat acacattcta tcatctatat
      541 ttgcagaaat caagtaaaaa caccaaaaga tttccaaaaa taaaatattc tatttccttt
      601 acgacagaat ggacgtctta aaatattgat ttaataggct ttgagtagtt gtaagttctt
      661 aagtatcaaa ctcaaaatcc agtgtccgca aggacgtgcc ggttcgaccc cggccgccgg
      721 tatagtttaa aagacaaggt ttctaagcct tgtctttttg ttttgaggtt ataaaatttt
      781 cagttgagtt actaaaaatt acttaatgtt ttgttgtata ataagttata taagcaagag
      841 gaggagccat tatatgaaga cactttatca ttatacaaca gttgaaacat tgcttctgat
      901 attaaattat aaaacattga gattcaaaag tttactttat gttgacgatc cattagaacc
      961 ttcaacttca gactttggta atctaggtgg atttaagtat gtgtcttgtt ggactgatac
     1021 tcctaatagt attccacaat ggacaatgta ttctgataat atgacaggag tgtgtatagg
     1081 aattagtttt gacaaagaaa ctgatgtctt tttaacggaa aaattttctt tatctgaatc
     1141 ttctgaacca attgatatgg taaatgcatt acatccttta aaatcaggct tattagttac
     1201 aaataataaa tatgtgcctt ctttggaaca aataaggtat actgatgatg tttcattgat
     1261 cactcctcga gtagtttctt cagatgataa atccacaact attaatttag cttcaaatgg
     1321 tatctataag acaactgatt ggagttttca aaatgagcaa agattttctt ttcaaatttt
     1381 tccattacca atagatttag ttttggaatt aatgaatgca aataaaggag atttgactga
     1441 aataattaat agttttattt ctgttaaacc taaagaatac tttgatttag atttaaatcc
     1501 gactatattc agtaatatga caattacgtt tggtaaaaga tgctctgctg aagataagtt
     1561 gaaagtatca aaatttttag aggataataa attccatatt cctttatttg atagtactgt
     1621 aaatataaag ccttaaatta ggtcatctaa tttatctgct aaatcttttt gcttgcttgg
     1681 atacaagtga gaataggtat cgattgaagt tgttataaaa gcgtgtccta gcctttcttt
     1741 cacaactaaa taatcttccc ctcgatttat caatagagaa gcgtgtgagt gcctaaaatc
     1801 atgtatgcgt atctttttaa gagccgcatc acgttcaaga atttttttgt actgcttttc
     1861 tattgaattt tttgtaatcg taatgggact actttgaaac actgacatcg aacagacatt
     1921 agctagaggg ctggctggac tacagttacg aattgaacaa attattctgg ctcataactt
     1981 acgctatttt gaaatgaact agcaccacgg gtggcttata cctttattaa cgtatacaga
     2041 ctttgtgata tgaattgtat tgctcgaaag gtcaatgtct tgccatgtta gtgcgagtgc
     2101 ttctctaagt cttagatctg taaagaatag gactgtaaag agtaattttt atttaccatt
     2161 ttcaactaaa ctctttaatt ctaaatgtac tttattgttc tcaagttcta ccttattttt
     2221 tcgtctcagt ctagtttcta gttctcgagt cagactagta cttactttga gaatttagct
     2281 tttaaatatt ttccttgttt ttttgttttc tatgtggtat acttaacaag ttaattaaaa
     2341 ggttaagggg atgcctatga atcgtattgc attagaaatt gagaagtacc tgcacgagat
     2401 tgttttgagt tcggagaatc aattagagat tttggttggt tcttgtcaaa gcacggtgaa
     2461 gttgacgaat acgcaggagc atattttgat gcttattgaa aaggctgcat atactaatac
     2521 tgagattgct aaggagttga atgttagtca ggctgcgatc acgaaggcta caaagtcatt
     2581 agttgctcag gggttattgg tggcggttag agatgataag gatgctcgta ttgttcgctt
     2641 tagtttgact gaggctgcta agcctattgc tgcagagcat gctcatcatc acgcgcatac
     2701 cttggaagct tatgaagagc ttttggaaaa ttatagtctt gaagagcagg agtcaattgc
     2761 tcgattctta agtgagttag tggagaagat tagaaaatag atgagatata ttactgtgga
     2821 agacttgtcg ttttactacg acaaagaacc ggttttagaa catattcatt attatcttga
     2881 tagtggggaa tttgtgactt tgactggtga gaatggcgca gccaagacaa ccctcattaa
     2941 ggcgactttg gggatattga agcccaaaca agggaaggtt tctattgctg agaagagtat
     3001 aaaggggaag aagttgagaa tggcctattt acctcagcaa attgcaagtt ttaatgctgg
     3061 ttttccgagc acggtttacg aatttgtaaa atcagggcgt tatcctcgac aaggttggtt
     3121 tcgtcgtttg acagctcatg atgaggaaca tgttcggatt agtttggaat cagttggaat
     3181 gtgggaacat cgggataagc gcttaggtgc tttgagtggt gggcagaagc agcgtgcggt
     3241 cattgcgcgt atgtttgcct ctgatccaga tatttttatt ctggatgaac cgacaacagg
     3301 gatggatgca gggaccaagg atgcttttta ccaactcatg caccattcgg ctaagaagca
     3361 tggaaagtcg gttttgatga taactcatga tcctgatgag ctgaataagt atgctgatcg
     3421 aaacattcac ttggttcgtg atcagcagtc tccttggcgt tgtttcaatg ttcatgaagc
     3481 ggatgaggag gttgcccatg tttgatctat ctgtatttca ttatgacttt atgcagcgtg
     3541 ctttcctggc aatcattgcg atgagtctgt tctcgcccat tttgggggtc ttcttgatac
     3601 tcaggcggca aagtttgatg tcggatactc ttagtcatgt ttcgttggcg ggggttgcat
     3661 ttggtttggt attggggatt tcaccaacgc tttcgactgt tcttgtcgtt attgtggcag
     3721 ctgtattttt agagtatttg cggacaattt acaagaattt tatggaaatt gggacggcta
     3781 tcctcatgtc gactggtttg gctatttcgc tcattgtcat gaataaatct ggtgggaaat
     3841 cagggcttag cctggaacaa tatctgtttg gttcgattgt gacgattagt caggagcagg
     3901 taattgcttt gtttacgatt gctgtgattg tcatcgtgct gacattgttg tttttacgtc
     3961 cgatgtatat tcttaccttt gacgaggata cggcatttgt agatgggtta cctgtgcgag
     4021 caatgtccat tgccttcaat gtggtgactg gtgtcgccat tgccttaatg attcctgcgg
     4081 caggtgcttt gctggtttca acaattatgg ttttgcctgc ttctattgca ttgcgacttg
     4141 gtaagagctt taaagctgtt atctttactg ggatgggtat tggctttttt ggaatggtta
     4201 tggggttgct gacttcttac tatgcagaaa ccccagcgag tgcaagtatt accttgattt
     4261 tcattagtat tttcttactg gtgaatgttg ttcaaaaatt taaaaaataa ggagttaaga
     4321 tgaaaaaagt tggtttatta ttcttgtctg tctcagcttt gcttttgggt gcttgtggca
     4381 atagcacagc ttctgaagat gggaagttga atattgtaac gaccttttat cctgtttatg
     4441 agttcaccaa gcaggtggca ggtgatgagg caaatgttga tctgttggtt aaggctggga
     4501 cagaggttca tggttatgag ccgtcagcca aagatattgc tcgtatccaa gaggcagatg
     4561 cttttgttta tgaaaatgaa aatatggaaa catgggtcca tgatgttgaa aaatcacttg
     4621 atacaacaaa ggttaatgtg attagtgcga cggaggggat gttgcttttg cctggtggtg
     4681 aggaggaaca tgaaggtcac gaccatagtg aggaggggca tagccatgct tatgacccgc
     4741 atgtatggtt gtctcctgag cgtgccatca cacttgtaga aaatattcgt gatagtttgg
     4801 tagctaaata cccagaaaag aaagatgctt ttgaaacaaa tgcggcagcc tatattgaga
     4861 aattagatgc tttggatgct aaatattctg aaacattatc tgctgcgaaa cagaaatact
     4921 ttgttacaca gcatactgca tttgcatatt tggctttgga ctatggtttg aaacaagttt
     4981 ctattacagg tgttgctgca gatgaggatc caactccatc acgtctagca gaattgacag
     5041 agtatattaa taaatatggt attaagtata tctattttga agaaaatgcg tcaaaatctg
     5101 ttgcagaaac acttgccaaa gagactgggg ttcagttgga cgttcttaat cctcttgaaa
     5161 gtttgacgga tgaggatatg aaaaatggta aggattatat ttctgttatg gaagataatc
     5221 tgattgccct tgaaaaaaca acttcccaag aaggttctga aattttgcca gaagaaggtg
     5281 ctgagactgc gcaaactgtt tataacggtt attttgaaga tagtgccgta aaagatcgta
     5341 ctctttcaga ttatgcaggt gagtggcaat ctgtttatcc atacttgctt gatggtacac
     5401 tagatcaggt ctgggattac aaggctaaga tcaaaggtgg tatgacagct gaagagtaca
     5461 agacttatta cgatactggc tacaaaacag atgttgatca aattaacatt acagataata
     5521 ccatggaatt tgtagtggga gataagaaag aaaaattcac gtataagtat gtgggttata
     5581 agattttgac ctacaaaaaa ggaaatcgtg gtgttcgttt cttgtttgaa gcaactgatg
     5641 caaatgctgg taactataag tatgttcaat ttagcgacca caatatcgcc cctgttaaaa
     5701 caggtcactt ccatatctat tttggtggag agagccaaga aaaactcttg gaagagttgg
     5761 aaaactggcc gacatactac cctgttggtt tgactggttt ggaaattggt caggagatgc
     5821 tggctcacta agaataatga gaagactggg caaggtgttc agtctttctt cttgacaatt
     5881 tttgactaca aatgtaaact gaagttagaa aattattgtt gggaggtgaa tgtgtggagc
     5941 agacaatttc tgctgcggag tggcaggtca tgcgggttct gtgggcccat cctggtgcga
     6001 cttctcagga aattattcag gccttgcagg aaggctttga ttggcaggcg acgactatta
     6061 agacactttt agggcggctg cggaagaaaa actatttgag aatggctaag gaaactagca
     6121 agtaccacta ttatccgctg attagtgaag aggaacattt gcaggggcag gtggagctct
     6181 tactagctgc catatgttcc acaaaacagg ggcaactggt tgaaaaactg ctagacacag
     6241 ggacattttc caaaaaaagc ctagaaaatc tggccagcaa aatctcgcag ttacaaagga
     6301 ctgcacctga gcaaatcgct tgtcggtgct tggctgggca atgtacctgc gggcatcatc
     6361 atactcttcg aaaatcaacc tcagacgttg ttgacttgac ttgatgagtg taaagctcct
     6421 gtggagcttt acagcctact acctgaaaat gcgaaagtag tagggttcta tctgctcttg
     6481 gagaaacgaa gacgttcgct ttatttccaa ccttcaaagg ttccccgaac ctttgaagct
     6541 agtctgaatc tgattttcat tgagtataaa aaaggagaaa gaacatgaag caaactttga
     6601 aattgaaaaa cttatcgtgc caaaactgtg tcaagcatgt gaccaatcac ctcttggact
     6661 tggatggggt ggaagaggtg aaaatccagc tggaagagca gttggcggag gtggcaacct
     6721 ctgtggccta tgacttggaa cggtaccaag aggtgctgga agatactatc tatgaagtgg
     6781 aagagttggt ataagcgaaa aagcagccgt cgggctgctt tttataatgc tttgagaaaa
     6841 tgagtcaggt ctagttgcgc ttgtgcaagt gaaatttggt cccagaagcc gtctgatcga
     6901 aagcgtggaa ttaggtggac atggaaatgg gtgccagcat taaacaagcg atcgttgcag
     6961 gctgtggtca caccgtcaat tgccaatgtt tgacagagtt tttcagtcaa aaatacttcc
     7021 aagtccgata gttcatagcg aatagtaggt gggacttgac tgagtgtgtc atagtggtct
     7081 ttgctgataa tcaacagatg cccagtttga atagggtcaa tgtcccagac caccttgaaa
     7141 tattctgtct ggtagagaat atctatttct tcaatctgat ggcaaaaaat acaggtcata
     7201 gctgttctcc tattgataga acaaaaggaa atcatggtgg atttccttga aaaatcttaa
     7261 taagtcaaca cagaatactt cttcttccca cgacggataa cggttaactc gccgtcaatc
     7321 ttgtcactgt cagaaagggt atagtccaag tcttgcacac gctcaccatt gacataaatg
     7381 gcaccatttt gtacatcttc acgagcttgg cgttttgaat tgacaatacc agaggtaact
     7441 agaagttcca cgatgttaag gttgtcttca gcctgtacag cgtagtttgg aacgttgctg
     7501 aggccttgtt tgagttcttt tgcggatagg tttttgatat tgccagcaaa caattgctcg
     7561 gtgatgttaa gggcttggtt ataggcttct tcaccgtgga ccaatgtcac gacttccttg
     7621 gccaaaatct tctgagccag gcgttcatga cgggcagcgt caaattgttt ctcgatttca
     7681 gcaatctcat ctaatgacaa gaaagtaaag attttcaaga aacgaacggc atcgtcgtcc
     7741 atgacattga gccagaattg gtacatttca tacggagaag tcttgtcggc atccaaccaa
     7801 acggcgttgc cttcagactt accaaatttc ttacctgttg agtcggtgat aagtggcaca
     7861 gtcatcacgt gaccagactt gtcagccttg cggcgaagca attcagtacc tgcagtcata
     7921 ttgccccact ggtcagaacc accgatttgt agggtcacat tgtgcttgtc attgagctcg
     7981 tagaagtcat agccctgcat gatttggtag gcaaactcgg tgtaggaaat ccctgtttca
     8041 atccgttttt ttacagagtc tttgctcatc atgtagttga ccgtgtagta tttaccaaca
     8101 tcacgaagga agtcgataaa gctgatgtct gagaaccagt cgtagttgtt gaccatttca
     8161 gccttgttgt caccattttc aaaatccaag aagcgagaga gctgaccttg gatttttgtt
     8221 acccagccgt ccacggtgtc tttggtttgc aagctgcgct ccgcatcctt gaaggaaggg
     8281 tcgccaatca gaccagttgc accgccaact agggcataag gcttgtggcc tgctaactgc
     8341 aagcgacggc tagttaagat agcaaccaag tgccccaagt gtaaactatc tgctgttgga
     8401 tcgtatcctg tgtaataaga aacctgtcct tctgtcaatg cttttaccaa ggcttcttcg
     8461 tctgtcgttt gaaagaccaa gccacgagct tttagttctt caaaaatgtt catgtgggct
     8521 gtctccttta ggtttaatat acaggaccat aaaccatttt atatgatttt tggaccgaac
     8581 ttcattttaa aaaattcctc cctattatac cacgaaattg cggaaaataa acaaaatttg
     8641 gtataatgga acgataagga gttaatatgg cgactaaatc agataagcaa gattttaaaa
     8701 agaaaatcag tgccctaggc ttaggggatg tagtaggagt tttccttcgg acgctgaaat
     8761 tattattcaa ttcagtagct gtcttggtgt tcctattcgg tctttttggt gcgggtatag
     8821 gaattggttt cgtggttagt ctttttgatg acgttaagat tcccaaaaca gaggaactgg
     8881 tagcgaaggt ttcagaagtt agtcggattt ccaccgttac ctattcggat ggtagcttgg
     8941 tgtcggaagt taattcagat ctgcttcgtg tacctattac ttcggaagag gtctctaatt
     9001 atctaaaaca ggctgtaatt gcgacagagg atgaaacatt tgaaacccac aatggggttg
     9061 tgcctaaggc tgttttgcgt gcggcactgg gatcagttgg tctaggttca tctagcggtg
     9121 gttcaacctt gacgcagcaa ttgataaaac agcaacttgt cggagatgct ccaaccttta
     9181 cgcgtaaggc taatgagatt gtttcggctt tggcattaga gcggaatatg accaaggaag
     9241 agattttaac catttactta aatgtttctc catttggtcg aaataatcag ggacgaaata
     9301 ttgcaggggt agaagctgcg gctcagggaa tttttggtaa accagcgaaa gacttgactg
     9361 ttcctcaggc tgcttttatt gcaggcttac cgcaaagtcc gattgtttat tctccctatg
     9421 catcagatgg aacacgtaaa tcagatgaag atatggttta cggtattgaa cgctatcaag
     9481 atgttctctt taatatgtat cgggcgtcat tcttgaccaa ggaagaatac gaaacctata
     9541 aagcctacga tattaaacaa gattttattg ctccagctcc tgtaatggcg gatacgaaag
     9601 attatctcta ttacaaggtc atggaagaag cgcaagaggt tatgtttgat tacctggtga
     9661 aacgtgacaa ggtttctaaa aatgacttga aaaatgatga aacaaaggca tcctatgagg
     9721 agttggccaa gcaagaattg agccaaggtg gctacacgat taagagtacc gttgatcaaa
     9781 aaatctatgc ggcgatgcag tctgttgtgg caaactatgg atctgttttg gatgatggaa
     9841 acgaatatgt cgagacaggt agtgtgttaa ttgataatgc cacaggggcc attttaggat
     9901 ttgtgggtgg tcgcgactat gcaaccaacc aaaataacca tgcctttgat acccttcgtt
     9961 cgccagcgtc aaccatcaag cctctgttag cttacggtat tgcgattgat caaggtttga
    10021 taggttctgc cagcatcctt tcagattatc caacgaactt ttcaagtgga caaccgatta
    10081 tgtatggttc aggacgtggt actggtatga tgaacttaca gacggctatt gaccgttctg
    10141 ttaacattcc tgctttttgg acctataaga tgatgagaaa tgcaggtgta gatgccaaag
    10201 cgtacatgga taaaatgaat tatcatattc ctatgtacga tattgaaagt gtaccgttgg
    10261 gtggtggtgt tgaaatttca gtattgacaa ataccaatgc ctatcaaact ttggcaaatg
    10321 gtggcgttta taacaaacat tacattgttg aaagcattac tgcctctgat ggaacagtag
    10381 tgtatcagca tgaagcgact ccggttcaag tctattctaa agcaactgca agtattatga
    10441 accagctttt gagacaggtt gtcaactctg gttatactac gacgttcaag agtcgattga
    10501 gtggtttaaa cccacaggca gcatcatctg atttcgtcgg taagacggga acaagtaatg
    10561 aagtcaatga cgtgtggctc atgctatcaa cccctagagt aactttaggt acctgggctg
    10621 ggaatgatga taactcagaa atgtatgtct ggacaggcta ccacaataat tcacaatatg
    10681 tggcccatat ggttgatgcg ctttacaatg ttaatgcgga tatgttcgca ggaaaatttg
    10741 aattagacag tagtgttatt gcttctagcg tcgttgcttc tacaggtcaa cgtgcaggga
    10801 caacacaggt aaatgggcgc caagtaacag ttggcggtgc gatgacaact agttattggg
    10861 ctaaaaatgg tgcaccggta acgagctata acttcatggt tggggggaca gatagtgatc
    10921 gagcacaggc ttggaataca attatcggct cccaaacggc aacatcaagt agctcaaccc
    10981 aacgaagcag ttcgactcgg agtagcacga gttcttcagc taataacacg aaccagtcat
    11041 cagaaacgca aacagcaact agtgagcaag cgaataatga ttcaccttga tttttcctag
    11101 tacttgtgct ataatggtat aaattatttg tcgtgtgtct tgtttgaaat attgtccaaa
    11161 caaggcttgc agcagttaaa tcaaactttt tcaaaggaag atttagctgc tctttttgtg
    11221 tctatgagga atttttttga gaattgttac ctattcttaa agattctaaa aattcagaaa
    11281 aaggatgaat gttggtcatc acatggctgt atataattga actcgaccta aaacctgtgt
    11341 gaaaaagtgt atgaaatatt tactttggtt tgtcactccc aacgtcgtaa acgtctggtc
    11401 tttcttcgac attctgtcta gaaagcccta gtcgttctga cgagggtgcg ttaacgaaat
    11461 caaagatttc ggacttaccg cttattctca ctttggtttt cacggtctcg tatcttatta
    11521 caaaggagaa aacttttggc aggacatgaa gttcagtacg gtaagcaccg tacccgtcgt
    11581 agtttttcaa gaatcaagga agttcttgat ttaccaaatt tgattgaaat tcaaacggac
    11641 tctttccaag actttttaga ttacggtttg aaagaagtct ttgaagatgt acttccagtt
    11701 tcaaacttta cggataccat ggaattggaa ttcgttggtt atgaattgaa agagcctaaa
    11761 tacacattgg aagaggcgcg tgcgcatgat gcgaactact cagctccaat ttatgtaact
    11821 ttccgtctgg tgaataaaga aactggcgag atcaagacac aagaagtctt cttcggtgag
    11881 tttccaatca tgactgaaat gggtaccttc atcatcaacg gtgcagagcg tatcatcgtt
    11941 tctcagttgg ttcgttcacc aggtgtctac ttcaatgata aagtagataa gaatggtaaa
    12001 gtaggttatg gatcaacggt tattcctaac cgtggagctt ggctggaatt ggaaacagac
    12061 tcaaaagaca ttgcctacac tcgtattgac cgtacgcgta agattccgtt cacaacgctt
    12121 gttcgtgcgc ttggtttctc aggcgatgat gaaatctttg acatcttcgg tgatagcgaa
    12181 ttggttcgca ataccatcga aaaagatatt cataaaaacc cagcagattc tcgtacggat
    12241 gaagcgctta aggaaatcta tgagcgcctt cgtccaggtg aaccaaagac agctgaaagc
    12301 tctcgtagtc ttttgacagc tcgtttcttt gacccacgtc gttacgactt ggcacctgtt
    12361 ggtcgttata agattaataa aaaactcaac cttcgtactc gtttgctcaa ccaaacactt
    12421 gctgagcatg tgattaacgg tgagacaggc gaaattgtct tggaagctgg tactgtcttg
    12481 agccgtgacg tgcttgaaaa agtagaagca caattcgatg agctcaactt ggtagaatac
    12541 attccaaatg acaatgctgt tcttcttgag ccagttcttt tgcagaaatt caagattgta
    12601 gctcctaagg atccagaacg tgttgtgacg gtgattggta atgctaatcc tgcagaaaac
    12661 gtacgtacag taacacctgc ggacatcttg gctgaaatga gctacttcct caacttggct
    12721 gagggtcttg gtcgtgtaga tgatattgac cacttgggta accgtcgtat tcgtgccgtt
    12781 ggtgaattgc ttgctaacca agtacgtatc ggtttgactc gtatggaacg taacttgcgt
    12841 gagcgtatgt ctgttcaaga caatgaagta ttgacgccac aacaaatcat caatatccgt
    12901 cctgttacag ccgcaatcaa agaattcttt ggttcatctc agttgtcaca gttcatggac
    12961 caacacaacc cactttctga gttgtctcac aaacgccgtt tgtcagcctt gggacctggt
    13021 ggtttgactc gtgaccgtgc tggttatgag gttcgagacg ttcactacac tcactatggt
    13081 cgtatgtgtc cgattgaaac gcctgaggga ccaaacatcg gtttgatcaa caacttgtct
    13141 tcttatggtc acctcaacaa gtatggcttc atccaaacac cataccgcaa gattgaccgt
    13201 gcaactggta cagttacaaa tgagatcgtt tggttgacag ccgatgaaga agatgcttat
    13261 attgtagccc aatcaacatc gccacttgat gaaaacaacc gtttcgttga taagattgtt
    13321 atgggacgtc accaaggtaa caaccaagag ttcccagcag attcagcaga tttcatggac
    13381 gtttcaccta agcaggtagt tgccgttgcg acagcatgta ttcctttctt ggaaaacgat
    13441 gactccaacc gtgccctcat gggtgccaac atgcaacgtc aggctgttcc attgattgat
    13501 ccaaaagcac cttacgttgg tactggtatg gaataccagg ctgctcacga ctcaggtgcg
    13561 gcaattatcg ctcaacacga tggtaaggtt gtttacgcag atgcggacaa ggtagaagtg
    13621 cgtcgtgaag atggctcgct tgatgtctac cacatttcta aattccgtcg ttcaaactcg
    13681 ggtactgcct acaaccaacg tacccttgta aaattgggcg acatcgtaga aaaaggcgac
    13741 ttcatcgcag atggaccttc tatggaaaat ggggaaatgg ctcttggtca aaaccctatc
    13801 gttgcctaca tgacgtggga aggttacaac ttcgaggatg cggttatcat gtctgaacgc
    13861 cttgtgaaag atgatgtcta tacatctgtt cacttggaag aatacgaatc agaaacacgt
    13921 gatactaagt taggccctga agaaatcact cgcgaaattc caaacgttgg tgaagatgcc
    13981 cttcgcaact tggacgaaat ggggattatc cgtattggtg ccgaagttaa agagggcgac
    14041 attcttgttg gtaaagtcac accaaaaggt gaaaaagatc tttctgctga agagcgtctc
    14101 ttgcacgcaa tcttcggtga caagtcacgt gaagtacgtg atacctctct tcgtgtacct
    14161 cacggtgccg atggtgtcgt tcgtgatgtg aaaatcttta ctcgtgccaa cggtgatgaa
    14221 ttgcaatcag gtgttaacat gttggttcgt gtttacatcg ctcaaaaacg taagatcaag
    14281 gtcggagata agatggccgg tcgtcacggt aacaagggtg tcgtttcacg tattgtacct
    14341 gttgaggata tgccatatct tccagatgga acaccagttg acatcatgtt gaacccactc
    14401 ggggtgccat cacgtatgaa catcggtcag gttatggaac ttcacttggg tatggcggct
    14461 cgcaacttgg gcatccatat cgcaacacca gttttcgatg gtgcaagttc agaagacctc
    14521 tggtcaactg ttaaagaagc aggtatggac tcagatgcca agaccattct ttacgatgga
    14581 cgtacaggtg aaccatttga caaccgtgta tctgttggtg tcatgtacat gatcaagctt
    14641 caccacatgg ttgatgataa acttcacgcc cgctcagtcg gaccatactc actcgttacc
    14701 caacagccgc tcggaggtaa ggctcagttt ggtggtcagc gtttcggtga gatggaggtt
    14761 tgggcccttg aagcctacgg tgcttcaaac gtccttcaag aaatcttgac ttacaagtca
    14821 gatgatgtga caggccgtct gaaagcctat gaagccatca ccaaaggtaa accaattcca
    14881 aaaccaggtg ttccagaatc attccgcgtt cttgtcaaag aattgcaatc acttggttta
    14941 gatatgcgtg tccttgatga agacaacaac gaagtagaat tgcgtgacct tgatgaaggt
    15001 gaagatgatg acatcatcca cgtagatgat cttgaaaaag cacgtgcaaa agccgcagct
    15061 gacgcagccg cagcctttgc agcagaagaa gcagaaggca aagaataatt agaatggatg
    15121 gaacaagttg gtccaaacct cagaactgaa agagataagg gccaacggtc ttccaccgtc
    15181 tgatttatag aaaaatagct taccagctat ccattctgct gattattgtt caagaatttg
    15241 aggtatggga atccatcctc tcacaagaaa agaaagggat tattagtggt tgacgtaaat
    15301 cgatttaaaa gtatgcaaat cacgttagct tcaccaagta aggttcgttc atggtcttac
    15361 ggtgaggtta aaaaacctga aacaatcaac tatcgtacac ttaaaccaga acgtgatgga
    15421 ctttttgacg aagtcatctt cggtccaaca aaagactggg agtgttcatg tggtaaatac
    15481 aagcgtatcc gttataaagg gattacttgt gaccgctgtg gtgtagaagt gactcgtgca
    15541 aaagtacgtc gtgaacgtat gggacacatt gagttgaaag caccaatttc acacatttgg
    15601 tatttcaaag gtattccaag tcgtatgggc ttgaccttgg atatgagccc acgtgcgctt
    15661 gaggaagtta tctacttcgc agcttacgtg gtgatcgatc cgaaagatac accgcttgag
    15721 cacaagtcaa tcatgacaga gcgcgaatac cgtgagcgtt tgcgtgaata tggttatggt
    15781 tcattcgttg ccaaaatggg tgcagaagcg atccaagacc tcttgaaaca agtcgatctt
    15841 ccaaaagaaa tcgcagcttt gaaagaagaa ttgaaaacag cttctggtca aaaacgcatt
    15901 aaagcagttc gccgcttgga tgtattggat gctttctata aatctggtaa caagcctgag
    15961 tggatgattc tcaatatcct tccagttatt ccaccagatt tgcgtccgat ggttcagttg
    16021 gatggtggcc gttttgccgc atctgacttg aacgaactct accgccgtgt tatcaaccgt
    16081 aacaaccgtt tggctcgtct cttggaactt aatgctccag gtatcatcgt acaaaacgaa
    16141 aaacggatgc tccaagaagc tgtggatgct ttgattgaca acggtcgccg tggtcgtcca
    16201 attacaggac caggtagccg tccacttaaa tcactcagcc acatgcttaa aggtaagcaa
    16261 ggacgattcc gtcaaaactt gcttggtaag cgtgttgact tctcaggccg ttccgttatc
    16321 gccgttggtc caactcttaa aatgtaccaa tgtggtgtac cacgtgaaat ggctatcgag
    16381 ctcttcaaac cgtttgtcat gcgcgaaatc gttgcccgtg atattgctgg aaacgtaaaa
    16441 gctgcaaaac gtttgattga gcgtggtgat gatcgtattt gggatatctt ggaagaagtg
    16501 atcaaagaac acccagttct tttgaaccgc gcacctaccc ttcaccgttt gggtatccag
    16561 gcttttgagc cagttctaat cgacggtaaa gcccttcgtt tgcacccgct tgtctgtgaa
    16621 gcctacaacg ccgactttga cggtgaccag atggcgattc acgttccatt gtcagaagaa
    16681 gcacaagcag aagcacgtat ccttatgctt gcggcagaac acatccttaa ccctaaagat
    16741 ggtaaacctg tcgtaacacc atctcaggat atggttttgg gtaactacta cttgaccatg
    16801 gaagatgctg gtcgtgaagg tgaaggtatg gtcttcaagg atgcggatga ggctgttatg
    16861 gcttaccgca atggctatgt tcacttgcat actcgtgttg gtatcgcaac agatagcctc
    16921 gataaacctt ggaaagacaa ccaaaaacac aaggtcatga tgacaactgt cggaaaaatc
    16981 ttgttcaacg caattatgcc agaaggtctt ccatacttgc aagagccaaa caatgctaac
    17041 ttgacagaag gaactcctga taaatacttc ttggaaccag gatcagatat taaggctgcc
    17101 attgcagaat tgccaatcaa cccaccattc aagaagaaaa atcttggtaa catcatcgct
    17161 gaaatcttca agcgtttccg tacaactgaa acatcagccc ttcttgaccg tttgaaagac
    17221 ttgggttatt atcactcaac actcgctggt ttgacagtgg gtattgccga tatcccagtt
    17281 atcgacaaca aggctgaaat cattgaagaa tctcacgaac gtgtagaaca aatcaagaaa
    17341 caattccgtc gtggtatgat tactgacgat gagcgctatg cagctgttac agatgaatgg
    17401 cgttcagcta aggaaaaatt ggaaaaacgc ctggttgaaa aacaagatcc taagaaccca
    17461 atcgttatga tgatggactc tggtgcccgt ggtaacatct ccaacttctc ccagttggcc
    17521 ggtatgcgtg gtctgatgtc agctccgaac ggacgtatca tggaattgcc aatcttgtct
    17581 aacttccgtg aaggtctttc agtattggaa atgttcttct caactcacgg tgcccgtaag
    17641 ggtatgacgg atacggcctt gaagacagcc gactcaggtt acttgactcg tcgtttggtt
    17701 gacgttgccc aagacgttat tatccgtgaa gacgactgtg gaacagaccg tggtcttgac
    17761 atccgttcaa tcacagatgg caaggaaatg atcgagccac ttgaagagcg tttgcaaggt
    17821 cgttacacta agaaaactgt taaacatcct gaaacgggtg ccgttatcat tggtccaaac
    17881 caattgatta cggaagatat tgcccgtgaa attgtcaatg caggtgttga acaagtaacc
    17941 atccgtagcg tatttacatg taacactcgt cacggtgtct gccgtcattg ttatggtatc
    18001 aacttggcga caggtgatgc ggttgaagtg ggtgaagcag ttggtacaat cgctgcccaa
    18061 tcgatcggtg agcctggtac acagcttaca atgcgtacct tccacacggg tggtgtagcc
    18121 tcaaacagcg atattacgca gggtcttcct cgtgtccaag agatctttga agcccgtaac
    18181 ccgaaagggg aagcggttat cactgaggtt aaaggtgaag ttatcgctat tgaagaagat
    18241 gcttctactc gtaccaagaa agtctttgtt aaaggtaaaa ctggcgaagg cgaatatgtg
    18301 gttccattta cagcccgtat gaaggttgaa gttggggacc aagtcgcgcg tggagcagcc
    18361 cttaccgaag gttctatcca accaaaacgc ttgcttgaag tccgtgatgt cttggcggtt
    18421 gaaacttacc ttctttctga agttcaaaaa gtttaccgta gccagggtgt agaaatcggc
    18481 gacaagcaca tcgaggtaat ggttcgtcaa atgcttcgta aagttcgtgt catggatcca
    18541 ggtgacacag atcttctcat gggtaccctc atggatatca cagactttac agatgccaat
    18601 gcggaagtgg ttattgcggg tggtattccg gcaacagctc gtccagttct tatgggtatc
    18661 acgaaggctt cccttgaaac caactcattc ttgtctgccg catccttcca agaaacaact
    18721 cgcgttctta cagatgcagc tattcgtggt aaacgtgaca accttctcgg tcttaaagag
    18781 aacgttatca tcggtaagat tatcccagca ggtacaggta tggcccgcta ccgtaatctt
    18841 gaaccacaag ccatcaatga agttgaaatc attgaagaca cagtagcaga agagcttgct
    18901 gcagaagcag agcttgaagc tgtaactgaa taaattaaga tggcacatct ctctctttga
    18961 gggatgtgtt tttgatattc ggaaagaaac catatatatg acttgataag gaattaacaa
    19021 gcagaatgtt ttcttaaatc atacaatttc gatataatgt gtacgaaaaa ggaagtaata
    19081 ttatgtatca agttattaaa atgtatggag attttgaacc ctggtggttc ttagatggtt
    19141 gggaagagga tgttaccagt agggctgctt ttgatcgcta tgaggatgca ctgaatgcct
    19201 ttcaaaaaga gtgggtacgg ctatcagagg attttccaat gaagaaaagt aagaatggaa
    19261 cgatggtggc tttttgggat gaatcagacc agcattggtg cgaggaatgc gatgaatatt
    19321 tgcagcggta tcattcgctg atgttggtag aagcgagaga aaatttaccg gctggtttta
    19381 ttaagcaacc tacgcaacct cgtgtacgcc cctgcaaatt aaaacaaaat aattgcgtaa
    19441 atgaataata aaagaggatt gacctttgcg ggtcaatcct ttttagctga atctgatagt
    19501 aaatgcttcc gcatcaagtt caacatgctc gccaatccga atggtaaaca gaggctgggt
    19561 atgggcaaag tccaaatcat agagaacagg gctggttttg agagtagggt gcttgtccaa
    19621 aatcgccagc aaaatctcct ccgtcatctt ggtctcttta ggaaaacgac cgaagacaag
    19681 agcctgtgga tttggatagg cttgtaaaag tgcagtcaag tgacgagcga taatgagata
    19741 atcgtcgtct tccgcctcct ctaaaaatag aatatattcg tctggtctgg gagcaaactc
    19801 tgttccagtc agtaggttga gatatttcca ccaatggcaa taccagaggc ctggcctgga
    19861 ttgtagactt tccattctgt tgggtaaaag gtgcgagggg cgtctggtag gtaccaagcg
    19921 tcgctagacc attctggact cggggtcaag tcaaaggagt cttgtgtcac agccttgagc
    19981 caggcctgag tctggtaatc ttgtccctca cgcatcttaa agctgctata gaatggtccc
    20041 atgtaagtct gtatacctgt tttggcatag atggcattga gcagggcagt tgtgtccgaa
    20101 taaccacaga aaatctttgg attgcgggca attatgtcaa aattcaaata aggtaatagc
    20161 tcattgcagt tgaaaccacc aatggttgtc aaaatggcat cgaccgactc atccgcaaag
    20221 gctgcttcca agtccgcaac acgactggca atcggagccg aatcgaacat atcattttca
    20281 aaataatgtt ctgagaaaga gagtttgaag cccagatttt ctagtttttc cttggcggca
    20341 agattggcct caaaaccacc aactctttcg atagaagatg acgggctgac aatgcgaata
    20401 tggtcgcctt tttttaattt tttcatagga agctccaagc ttttttatta ttttaacaaa
    20461 aaagtatgga aaatcaagtc tccttacgaa ttgatagggt gaggaggttg tatgattcaa
    20521 gaaaaagcaa gaaagatgat tgaagaggcg gtggcggata gggtcagtga catttatctg
    20581 gttcctcgtg gtgagtgtta ccaagtctat catcgtatca tggacgatcg ggaatttgtg
    20641 caagacttgg ctgaggagga agtaacagcc atcatcagcc atttcaagtt tttagcaggt
    20701 ttaaatgttg gcgaaaaacg ccgtagccag cagggttcct gtgactatga ttatgggagc
    20761 ggagagattt cacttcgctt atcaactgtc ggagattatc gtggcaagga aagtttggtt
    20821 atccgcctgc tctatgacaa tgacaaggaa ctcaagttct ggtttgaggc ggccgagcgg
    20881 cttgcagaag aaatcaaggg acgagggctc tacctttttt cgggtccagt cggctctggt
    20941 aagaccacac ttatgtacca tcttgctagg ctgaaattcc cagacaagca gattttgacc
    21001 atcgaggatc ctgttgaaat caagcaggag gacatgctgc aactccagct caatgaagcc
    21061 atcggagcca cctacgacaa tctgatcaaa ctgtccctcc gtcatcgacc agacttgctc
    21121 atcatcggtg aaattcggga tgcggaaacc gctcgagcag tcattcgagc cagcctgaca
    21181 ggagctaccg ttttctcaac agttcatgca aggtctattt cgggtgtcta tgctcgtatg
    21241 ttggaattgg gtgtcggtcc tgaggagtta aacaatgccc ttcaaggtat tgcctatcaa
    21301 cgtttaatcg ggggaggagg tgtggtagat tttgcaaagg gaaattacca aaaccattcc
    21361 gcagaccagt ggaatgcgca aattgatcgg ctttttgcag caggacatat cagtcttcgg
    21421 caggcagaaa cagaaaaaat tacccttggc tcgccagcgt aaggtcattg agcttttcaa
    21481 taatcttttt gccagtggtt ttcatctggg ggagattgtt gatttcctca aacgcagtca
    21541 gcttctggca gatccctata cccaggtctt gtcagacggg ttgctggcag gcaaaccctt
    21601 ttcgagtttg ctggcagatt tgcgattttc agatgcggtg gtcacacagg tggctctagc
    21661 agaagttcat ggtaatacca gcctgagttt gattcatatc cagtcctatc tggaaaatgt
    21721 cagcaaggtt cgtaaaaagc tgattgaggt ggcgacctat ccgattatat tgcttggttt
    21781 tctgcttttg attatgcttg gcttgaaaaa ctatcttctg ccccagttgg aggaaggcaa
    21841 tgcagcgaca gtgctgatta atcatctacc gaccatcttt ttatctctaa gtggacttag
    21901 tttggtggcg gtcttagctg gtatggtttg gtttcgcaaa accaataaaa ttaaggtctt
    21961 ttcctgcttg gcagctctgc catttttcgg aaaactcatc caaacctacc tgacggccta
    22021 ttacgccagg gagtggggga gtttgattgg gcaaggcttg gacctgccgc agattgtggg
    22081 cttgatgcaa gagcagcagt cgcagctttt tcgggagatt ggccaggacc tggagcagtc
    22141 gctttccaat ggtcagagtt ttcacgaaca cattaagacc tacgcctttt ttaagcggga
    22201 gctgagtttg attgtcgagt acggtcaggt caagtccaag ttgggtagcg agttgacagt
    22261 ttatgcggct gaatgttggg aggatttttt ctctcgggtc aatagagcca tgcagctaat
    22321 ccaaccgctg gtctttctct ttgtggcctt aatggtcgtt ctcatctacg cagccatgtt
    22381 gctgccgatt tatcaaaata tggagttgta aaatgaaaaa attagttgaa atgaaggtaa
    22441 aagggttcac tctggtggaa atgttggtcg ttttagggat cattagcctg ctcttgctcc
    22501 tctttgtgcc aaatttgagc cagcagaagg atgctattca gaagaagggg gatgcggctg
    22561 ttgtcaaagt agtggagagt cagatggagc tctatgaatt ggaacatgac gaggaagcaa
    22621 cggtggcaga tttgcaggcg aaaggttata ttactgaaaa acaagcaaaa cagtatgcta
    22681 cggcgaaaaa ataaggcttt taccctgttt gaaagcctgc tgaccttgtt ggttgtcagt
    22741 tttttagctg tttccttatc aggaacagta caaacggtct ttcggtctgt tcaggaagaa
    22801 atttttctct gggaatttga ggccatctat aaagacagtc agaaattagc agccagttcc
    22861 cacaaaaaag tgaaccttgc tatcggtgga caggaggtta caaatggtta tcaggctgta
    22921 gaggtgccca gaaacgtaga ggtcttagag gagaaaacta ttcagtttga agaagatggt
    22981 ggaaattctt ctctgaccaa gattcgtttt caccttagtc aaaaaatagt cacgtatcaa
    23041 ttatatatag ggagtggtcg ctataagaaa acagaagaat aaggcttata ttttgctaga
    23101 aagtctggtt gcccttgcga ctctagtgac catttgcagc ttgattttat cagctgtgga
    23161 tgcaggtcgt aggcgacagg tttgggaatt ggaacaacag gaggttttca acttagcaca
    23221 gatggctgtc cagacaaaac aagatgacct agccttaaac ggagttgcag ttcaggttca
    23281 acgaactgcg gaaagagttg cggttttcca tgaaggaaag gaggttttat cggttgttaa
    23341 aaagtaaaat tcctgctttt acactcttgg aatgtttggt ggttctagtc attctgtcag
    23401 gtagcctctt gatttttgaa ggcttatcca aattactagt ccaggaagcg cattatcaag
    23461 gtcagaccgt tcaaaaggaa tggttggtct tctctagcca attgcggtcg gagtgggacc
    23521 aggctgaatt ggtcaaggtt gaaaatggca aggtctatgt caacaaaggt gaacaggctt
    23581 tggcctttgg caagtcatgg tcggatgatt ttcggaaaac aaatgataga ggccagggtt
    23641 accaacccat gctctatcag gtggatagcg cagccatttc ccaagaaaac cagctggtgc
    23701 gcatcgactt tagctttaaa aacggagagg agcgaacctt tatctatgct tttaaagaaa
    23761 aaagttaagg ctggcatcct actctatgcc cttttgatgc tggctgtttt tagtctcttg
    23821 cttcagtttt atctccaccg ccaagaggct gagagtcgct tggtacaggt ggcaaggcaa
    23881 gaaacgactg cttatatcat ggctcagatg gtcttggaca aggtcgagca ggacctgcaa
    23941 gtagaaaaaa tagttacggg agcggtagtg aatgaaaagg aagcaaattt aaccacaggt
    24001 tctaagcaga aggagaatag aggaagggtc tcctttcaag agggacaggc tcgttatcaa
    24061 cttaaaggag accaactatt ggttacagtt gagttaacaa gtgatggtct gtatacctat
    24121 caatttcctt ttgggctatc atcagaagga gggtgagttg actcgttctc ctttttagtg
    24181 caaagtctgt gaaattttga taagatagga gtatgaattt tgaaaagatc gaacaggctt
    24241 acgacctgct attagaaaac gtacagacta tccaaaacca gctaggtact aatatctatg
    24301 atgccatgat tgagcaaaat gctacttacg tagctggtca gcatgagacg gatcttgttg
    24361 tcaaaaacaa tcagaccttg aaacaactag atttaaccaa ggaagaatgg cgtcgtgcct
    24421 atcaattctt gctcatcaag gccaatcaga ctgagcccat gcagtacaat caccagttca
    24481 caccagactc tatcggattt atcctatctt ttctagtaga ccaattggtg ccgactcaaa
    24541 aggtgacggt tctggaaatt ggttcgggga caggcaatct agctcagacc attctcaacg
    24601 ccagccagaa agaattggat tatttgggga tcgaagtgga cgacctcttg attgatttgt
    24661 cggcaagtat tgcggatgtc atgcaggcag atatttcttt tgctcaggga gatgcggtac
    24721 gtccgcagat tttgaaggaa agtcaagtaa ttttgggaga tttgcctatt ggctactatc
    24781 cagatgacca gattgctagc cgttatcagg tcgccagtcc aaaggaacat acctacgccc
    24841 atcatttgct catggaacaa tccctcaaat atctggaaaa agatggcttt gcgattttgt
    24901 tggctccaaa tgatttattg actagtccgc aaagcgattt gctgaaaggt tggttacagg
    24961 agcaagccaa tattgttgcc atgattgccc tgccaccaaa tctctttggg aagactgcta
    25021 tggccaagtc tatttttgtc ttgcaaaaga aagctgcaag atcgttgacg ccgtttgttt
    25081 atcccttaca aagtcttcaa gaaccagaag ctattcagaa gttcatgctc aatttcaaaa
    25141 attggaagca agagaatgca atttaagtga aaatctgtta tactagttag gaaaacgctt
    25201 taaaagaggt aagatatgtc aaaaacaatt gcaattaatg caggtagttc aagtctaaaa
    25261 tggcaacttt atcaaatgcc agaagaaaca gtactagcag cagggattat tgagcgcatc
    25321 ggtttgaacg attccatctc aacagttaag tatgatggga agaaagaaag tgaagtttta
    25381 gatattccta atcatacggt tgcggttaag attctcctag aagacttgct taaacacaac
    25441 atcatcgctg cttacgagga aattactggt atcggacacc gtgttgttgc aggtggagaa
    25501 tacttcaagg agtcagcggt tattagtcaa caagagattg agcaaattga agagttgagt
    25561 gccttggcac cacttcataa cccagcacac gtggcggcga tgcgcgcatt tgaagaagta
    25621 ttgccagagg tgttgaatgt agctgttttt gacactgctt tccatacaac aatgccaaaa
    25681 cacgcttatc tctatccgat tccacaaaaa tattatacag actataaagt tcgtaagtat
    25741 ggtgctcatg gaacgagcca ctactatgta gcgcatgagg ctgcaaaagt tttggggcgt
    25801 ccaatcgaag agttaaaatt gattacggca catatcggaa atggtgtatc catcactgct
    25861 aactatcatg gtgaatctgt ggatacttca atgggcttca caccactagc tggtccaatg
    25921 atgggaactc gttcagggga tattgatcct gctatcattc cttatttgat tgcgaatgtt
    25981 gaagaactga aagatgctgc agacgttgtt aacatgttga ataaacagtc aggcttattc
    26041 ggtgtatctg gcttctcaag tgatatgcgt gatattgaag caggtatcca agctcacaat
    26101 ccagatgcag tgttggccta caatattttc attgaccgta ttaagaaatt tatcggtcag
    26161 tatcttgcag ttttaaatgg ggcagatgct attgtcttca cggctggtat gggtgaaaat
    26221 gcaccgctta tgcgcaatga cgtagtagaa ggtttgtctt ggtttggtat tgagttggac
    26281 ctagaaaaaa atgtattcgg caactatggt gacatttcaa cggcagaatc aaaagttcgt
    26341 gtcttggtta ttccgacgga tgaagaattg gttattgcgc gtgaagtgga acgcttgaaa
    26401 taagaaaaac taactggtag tcggagactg ccagtttctc ttatagttta tacctttaga
    26461 aaggtatagt ttttagcaag tggacaaaat atatagtgtg tgatacaata gactagcaaa
    26521 gaaatttgca cagagtagat ggtttgcgtc aagtgtatgt ggatgggatg ttgccacata
    26581 ccgaagctga tctttgcttg catctgatgt ctcctagagt aggaacattg gtcctggctg
    26641 agagtagcgc ggtaaaccat tgcatccgct gtcgaataca cacgacagct ccattttttg
    26701 aaaaaggagc attttttatg gaaaagaaaa ttccaaaact aacggtgcag ttgttggctg
    26761 ctattgcgat gacccttgcc ttggtcatga ttgtagagaa ctatttctct attcggattt
    26821 ctgatacttt acaggttcag tttaccttca ttcccaatac tattttggga gctattgcgg
    26881 gtccagtttg ggcagctgtc tttgcggcta tttcagaccc agtctttgtc ttgtttagcg
    26941 ggcaaacggt cctcttcact tggattttga ttgaggcggt atcggcattt atctacggct
    27001 ggttcttcta tcgaaaaccg ctagacacca agaacaaggc tgattggctc tatgtggctg
    27061 gtgtagttgt cttgattcag gttgtgattt cctttatcat gacaccgatt gccctccatt
    27121 tccattttgg aacaccttgg attgttctgt atagcagtcg cttgattaag gcagtttttg
    27181 aaattccatt acgcattgtc gtgaccatgc ttgtcttgcc aagtttacaa aaaatacctg
    27241 aattggccaa gttaatgggc attaaataaa acagtatcaa gcaacaggtc atccccctgt
    27301 tgctactttt gtagagaggg aatcatgaat tatcaagaaa ctcgccggtg gctatctagt
    27361 cgtcctgcat cagatttaga aaatggcgtt gcacgtgtca actggatttt agaacgcttg
    27421 gacaatcccc agcttcaagt gccgaccgta cactttgtgg gcacaaatgg caagggctcg
    27481 accctcaacg ccttacagtc tatcttgcag tcttcggatt acaccgtcgg ccgctttaca
    27541 tcaccgtcta tcattgattt tcgagagcag attgtctacc agcaggagat gatttcggag
    27601 gaagattttg cgaggattgt gacagacttg caacccttga tcgaggactt ggaccagacg
    27661 gctggactgg atgccatctc ggagtttgag attgtagtag tggctatgtt tgtctacttt
    27721 gcccactacc agcgtcccga tattctcttg gtggaggccg gcatgggtgg tttgcaggat
    27781 gcgaccaatg tccttgcccc cttggcagta gtttgtccgt ccatcggttt ggaccatcag
    27841 gcatttttgg gagagaccca cgctgctata gcccgtcaca aggtcgccgt cttgcgtgag
    27901 ggggttccgc tcatctatgc gaccgaccag ccagaagtgg agacagtatt tgaggagcat
    27961 gcctgtcagc ttcagagtcc gacctatgcg gtggggcggg agattctttt ggaaaatagc
    28021 agagcaggct ttgcagtttc aagtcctctc ggccgtgtgg aagagttaac actacagatg
    28081 cagggtcgtc accaggaggt caatgcagcc ttggcagtga caacagctca gctcattaaa
    28141 cctcattttc caacaattac caatgaaacc atccgccagg gcttgtccca agccatctgg
    28201 ccgggtcgct tagagttgat taggcctaat ctcatgattg acggtgccca caataatgaa
    28261 agtatcgccg tcctgacaca actcttggaa gaaaagtatg ctgacaggga tattgaaatc
    28321 ctctttgcgg ccatcaatac caagccagtg gaccagatgt tgtcccagct tagccaattt
    28381 ggacctgtta gcgtgacgac ctttgacgat ttcagagcgg tacagttaga agattatccg
    28441 tcaggctatg aacgagttca gacctatcag gagtgggtgg agcaggcgga cttggacaat
    28501 cccaaaaaac tctacctgat tacaggctcg ctatatttca ttacctatgt gaggaagtac
    28561 attttagaag aacttgtata gaaaaaaaaa ggctttgccg ggcattcaac ccagcaaagt
    28621 cttttgtttt aataattttt aatcaaatca accgttgagc ggtctagttt tttaacgatg
    28681 gtctgcaaga aggcttgggc ctctaagaag tcatccatgc tgtagagagt ttgatgtgaa
    28741 tggatgtagc gagcgcagac accgatagtt gttgatggaa caccatgatt tttcaagtgg
    28801 gctgcaccag catctgttcc acctttacca cagtagtatt ggaatttgac acctgcttct
    28861 tcggcagttg tgaggaggaa gtctttcatg ttttttaaca tgatgtgacc tggatcatag
    28921 aaacgaagca gagttccgtc accaattttt ccttggtcgc cgtaaatatc tccagctggc
    28981 gagcaatcaa cagcgagaaa aatgtctgga ttgaacttgg ttgtagaggc atgagcacca
    29041 cgaagaccaa cctcttcttg cacattggcc ccagcaatca actgatttgg taaagcatga
    29101 ccggataggc tttctagcaa ttccgtcacc ataaggacac cgaagcggtt gtcccaagcc
    29161 ttagaaataa cattttttcc gttggctgtt agaattgttt catttttggg aacgaggaca
    29221 tcccccggac gaacgccgaa cgcccaagct tcgtcataat tggcaaaacc agcatcgaaa
    29281 ataatatcag caatggcagg catgccagga gcgttagccc ctcgtgaaag gtgaggtggt
    29341 actgagcctg agatggctgg aatggtacga ccgtcctgca actgaagagt gaaggcttgg
    29401 ctagaaacaa ccagaggatt ccagccacct agctcaacaa cacggaaagt accgtcaggc
    29461 ttgatttggc taatcataaa gccaacttca tccatgtggg cgaccactag gatacgagga
    29521 gcattttcaa cagccgtatc cttgatacca aaaattccac ctagcccatc tgtttcaatg
    29581 cggtctacat gtggcgtgat tttctggcgg atgtggttgc gaacctgtcc ttcaaatccc
    29641 ggtaagcttt gtaattcggt aacttcttta atttttccaa aaagagtcat tcttcttcct
    29701 ccatgacatg attactacta ttttatcacg aagagctaga cttgtcttga aaatatagaa
    29761 aaatatagaa aaatatggat agtattgaca agaatgattg aagtttgcta ggatagaaat
    29821 gcccctcaaa atagagaggg gagtgattgt taagtgtggg aagcatttat cgtcatttag
    29881 tttttctttt attacttcgt taattcgcct tgcctaactt cagttatgtc tgcggctcat
    29941 tgcctcgtac taaaagtaaa ctaaaagact atatcacagt ttttcttgta tctttgttcg
    30001 tcagttttct aacagttttg tttgaaagat ggctcaacaa tcgtgacaat agagtgggat
    30061 ttatgactta gagtttgtgt caacatctca gcgcagtggt tgattggtag atttgttcgt
    30121 gtttcacact ccaaatctga ccattacctt tgttgcgaac attgttcgct ctatctccaa
    30181 cctccaaagg ttccccgaac ctttggagct atgcgtgggt gagactgaaa cggtctggga
    30241 atagaccgtt ttagctcaac aactgaaaac aaggacttgt tgacgaactc ctttgttctg
    30301 tctcgctcca aaagaaaacc ctcaacgctg gtaacgttgg ggcattttga ttgccaagtg
    30361 ttgacaaaca tttatcactg taagaccatt ctatctattt ttaagtcttt tgtcaagtgg
    30421 tgcgagtttg tctcaactgt cacaagtcca atggcatttt tgggaaaaat cctgggaaat
    30481 atgataaaat agtcaacatg aaaaagaaaa agacagcctt gctagcaggc ttattggggg
    30541 caggtgtgct caccgctagt gctcaatttt accgtaaaat ccaagaagac cgtaaaaaag
    30601 cacaggcctt gcaggaggtg cgtgactttt tcgctgattt aggagagatt gccacggtct
    30661 atgtggatga aacggcttct acgcagacca ctcttatcgg aggggttgtg atggaggcag
    30721 gacaggtatt tttgtttgaa aataccaaag gttctattca atacagggag gaagaaagat
    30781 gatttttcca acaaatcatg aagaagtagc tgccttgatt gaagatggca agccaactgt
    30841 ttttctattt gtgacgactt ggtgtggaga ttgccactat attaaaccgc atgtgccagc
    30901 tatcgaagaa gcttttccag atctccgttt tgtgcaactg gatcgagatg actttatgcc
    30961 tttggcacag gaatgggcta ttttaggcat tccaagtctg gttgttttgg aaaatggtaa
    31021 ggaaatcggt cgttttgtcg ataagaatcg caagaccaag gaagaaatca tgaacttctt
    31081 atctggactg ggtagataaa ttagcagaga agctctgcca tttcccaaaa gaaaggaaag
    31141 aacatgaaga aatcattagg aaaaatcctt ctagcacctg tggtgctggg gttgagtttg
    31201 agtcttgctc ccttggtgca ggctgagatt caaacagatg ttatcaatga aaaatggggc
    31261 aagccaacac tagtctacgg tggaggtttg tcagatgcgc aggcgacaga ggttaacaat
    31321 ctatttggta tttcggatgt caataatgtc agtcgtcagg tggttgttgg tacggatatg
    31381 gaccaatatt taggtacatc tgaagcggac acagcctccc tctattcatc tgtcttggtg
    31441 caaaagcagg acgctggcaa aggggttgtg gtggatatta agacgccaca gaacatcacc
    31501 ttgattaccg aaacgcagta tgccaatgcg gctattacag ctggtgcgac agatgtcttg
    31561 attgatgtag cttctccgat tcaggtaacg ggggagtctg ctttgacagg tgtttacaag
    31621 gctctcgcag ccaatggtga aacagttgat acagcccgaa ctgaagtagc ccaacaagag
    31681 ctagagacag tcaatgaagt ggcgacggct catacaggtg acactaattt tgatagttcg
    31741 gccttggata aggcagtggc ggaaatcaag actgctcttg ccgactacaa aaagtccaat
    31801 ggtcaggtgg cttctgaggc tgacatcaac accatcatca atgatgtttt ggcccaaaac
    31861 ggtttggaaa atgtcatcac agcagatgaa gtttcaaaat tagttacctt tgccaaagct
    31921 tatcaggaaa cctctgctat tgattcggct gaggttgctg cccagctcaa ccagttcaag
    31981 caacaggcgg agcaacaaat ttcagaagcc tataagaatc tacaagattc agggatttta
    32041 gaaaaaatcg gtgccttctt tgaaaatctt tggaaaggct tgaccggtct atttgcataa
    32101 aggagaaatg aaaaagaaat gatttttaca tataataagg aacatgtcgg cgatgttctt
    32161 atggtgattg ttgcggagga caagggacag gctgtccagt ttgaacgcaa gggtcaagtg
    32221 gcgcgtgttt tcctagaaga aacaggaaaa acagtggcct ggaatatttt tgaagcatca
    32281 agtttggttg aacttgatgg aaatggtcaa gttttcttga cagatgaaca agttgcgacc
    32341 ttgaatgctg aattggctaa ggaaggtttt actgaaagct tggttaacga caatgctcca
    32401 aagtttgtag tcggtcagat tgtggaattg gttcctcatc cagacagcga ccacctcaat
    32461 atctgtcagg tcaatgttgg tgacaaaaca gtgcaaatcg tagctggtgc cccaaatgct
    32521 gcccaaggat tgaaaactat tgtggctctt ccgggggcaa tgatgccgag cggtagcctg
    32581 attttcccag gaaaattgcg cggtgaagat agctttggta tgatgtgtag tccgcgtgaa
    32641 ttggcactgc caaacgcacc acaagtccgt ggtattatcg aattagacga ctccgcagtg
    32701 gtcggagagg cctttgatcc agctaaacac tggaaggggt agaaaaagaa gaattggtca
    32761 ggtggccaat tcttttatgc tggttcaatt tttccttcaa tagcctgttc gatttcttcg
    32821 gtcgaggcct gttgtgattt gagttggaaa taaagactgg acaggaaatg ctggagattg
    32881 agccaccgga agtagtctac tggttcttga tttggaaagt ccagcttgct aatccattcc
    32941 gtcagctctt ggcttgacac tttttcattc agcaggaggt agacagggat ttgtgccaga
    33001 cggatttcct cgccagctga gaaaacttta ctttgtttag ttagacaagt gacaatagtt
    33061 tgccagactt ctttgctttt ttcagcggga aattgatcat gacagcttgt ggccagaaga
    33121 aaatctgctc cgtgggcagc ggtatggatc caaccgagtt tttcatcgta gccagaccag
    33181 tcattttcaa tcgtcaaata atccaaggcc tgctggaaga gtagctcatg gtcgtcagtg
    33241 cttaaaaatg catgataaat agactctggc tcattatcga cagacagcaa cagacagtaa
    33301 agtaggcaag taaaacttcg tttttgtgtg gggccttcta gggaaaatgg cttggtttct
    33361 tgagagaatt gcagtagcga ctgtgcttgt tctcttgtaa tcaagccctc caaaaagata
    33421 tggcaaaaac tagcatagac cagttcgtcg cgtatagtag ggtctggatg gccgatgttt
    33481 tccaacaacc aatccagttc ggcattggta tatggttggg aggtctgtat cttttccatc
    33541 aaaaattctt tcatgatttt cgctcctttt ctaatccttc tacgaataga taagtaggag
    33601 gatataatat gtataataaa acaattttaa tcggtcgctt gacggcccaa cctgaactca
    33661 ctcaaacacc aactggcaaa aatttgactc gtgtaactgt cgcagtcaat cgccgattta
    33721 agacagaaaa tggtgagcgt gaagcagatt ttctcaatgt tattttctgg ggcaaactgg
    33781 cggagacact tgtttcttat ggcagcaagg gtagtctgat ttctattgat ggtgagttgc
    33841 gaacgcgaaa atacgaaaaa gacggcagca accactatgt gacagagatt ctaggccaat
    33901 ctttccaatt actagaaagc cgtgctcaac gtgccatgcg tgaaaataat actggtgatg
    33961 acctagctga cttggtcttg gaagaggagg aattaccgtt ttaaagcaat atcagtccca
    34021 agaccgatgg agtgtattga aaaataggct atactatagt caatcctaaa tatttttcat
    34081 atctccttaa aaacaccgac gaaagttggt gtttttggct acttattttc tatatttcca
    34141 ccattctatc agcatgataa ttagagaaag taggagaact ccgtagaaga aaaagatgat
    34201 gtaatgaggg tgggaaaaga gaagccacca gactagccag agtaggtagg cgaatatcat
    34261 tttccccaaa aagcctaatt tacgttttaa aaaccattct gcaaaacttt cgtaggctga
    34321 aaatcggctt tcaaggtaat caatttttaa atctctaaaa aatttcatga atacccccta
    34381 actttttaaa aatagtatag cataatttag cggtaatgga taggcaagtt ctgtctcggt
    34441 ctcaagatgg attttcatga aaaagggata gaatgttctt gactattttt gaccaagtga
    34501 tacaatagga aatgtgaatt agcactcgaa tacaaagagt gctaaaaaga ccaggaggta
    34561 ataccatgtt gaaaccattg ggcgatcgta tcgccgtaaa aattgaagaa aaagaacaaa
    34621 cagttggtgg ctttgtccta gcaggcgcaa gccaagaaaa gacaaaagaa gcaagtgtcc
    34681 tagcgatcgg acaagggatt cggaccttga acggagactt ggttgcccca gcggtggcag
    34741 ttggagatac tgttttgatt gatgctcacg caggattgga agtcaaagac ggtgatcaga
    34801 acgttcacat catccgtgaa acagatattt tggcaattgt agaatagagg tagaaaaatg
    34861 gcaaaagaaa tcaaatttgc agcagatgcg cgtgaaagca tggtccgtgg tgtcgatatt
    34921 ttggctgaca cagtcaaagt aaccttgggt ccaaaaggtc gtaatgttgt cttggaaaaa
    34981 gcttacggtt caccactcat tacaaacgac ggtgtaacca ttgctaaaga aatcgagttg
    35041 gaagatcatt ttgaaaatat gggtgctaag ttggtatccg aagtggcttc aaaaaccaat
    35101 gacattgccg gtgacgggac aacaactgct actgtcttga cccaagctat cgtacgtgaa
    35161 ggcttgaaaa acgtaactgc aggtgccaac ccaatcggaa ttcgtcgcgg gattgaagcc
    35221 gcggttgcga ctgcggttga agccttgaaa gcacaagcaa gtcctgtatc caataaagct
    35281 gaaattgctc aggtagcagc cgtgtcttca cgttctgaaa aagttggtga gtacatttca
    35341 gaagctatgg agcgcgtggg aacagacggc gttattacta tcgaagaatc tcgcggtatg
    35401 gaaacagaat tggatgtggt tgaaggtatg caattcgacc gtggttatct gtcacaatac
    35461 atggtaacag ataatgaaaa gatggtagct gaacttgaaa atccatttat cttgattaca
    35521 gataagaaga tttctcatat ccaagatatt ttgccactct tggaaagcat tcttcaggcc
    35581 aaccgtccgc ttttgattat tgctgacgat gtggatggcg aagctcttcc tacacttgtt
    35641 ctcaacaaga ttcgtggtac attcaacgtt gttgcagtca aagctccagg ctttggtgac
    35701 cgtcgtaaag ccatgttgga agatatcgct atcttgacag gtggtacagt cattacagaa
    35761 gaccttggtt tggacttgaa agatgcgacc attgaagccc ttggtcaagc tgccaaggtt
    35821 gtggtcgaca aagatggtgc aaccattgtt gaaggtgctg gcaatcctga agccattgcc
    35881 aaccgtgtgg ctgttatcaa gtcacaaatt gaggtaacca cttcagaatt tgaccgtgaa
    35941 aaattgcaag agcgcttggc taaattgtca ggtggtgtcg cagttatcaa agtcggtgcc
    36001 gcgacggaaa ctgagttgaa agaaatgaaa ctccgtatcg aagatgccct caacgcaaca
    36061 cgtgccgcag ttgaagaagg aatcgttgcc ggtggtggta cagcacttgt aaatgttatc
    36121 gatagcgtag cgaaattgga gttgaaaggc gacgatgaaa caggacgcaa tattgtcctt
    36181 cgtgccttgg aagaaccagt tcgtcagatt gcctataacg caggctatga aggttcagtt
    36241 atcattgata aattgaagaa ttctgagctt ggcactggct ttaacgctgc gacaggcgaa
    36301 tgggtcaata tgatggatgc aggtattatt gaccctgtta aggtgactcg ttcggccctt
    36361 caaaacgcag cttctgtagc cagcttgatt ttgacgacag aagcagttgt tgccaacaag
    36421 ccagaaccag ctgctccagc tatgccacaa ggtatggatg gaatgggtat gggctactaa
    36481 gaaatagcaa aatgacacag ctacttggct gtgttttttt cttgaaaatt tcaaacatat
    36541 ctatttgaca atggttttgg gatgtggtac tatattagac ggtacttttt acttttggtc
    36601 tctcaagagt gtacagggac gtgctgacaa atgttgcaaa agtacacaca gataggggtt
    36661 gtcaccaatg ccctatcacc aaaaataaaa aatatataca ggagaatgta gatgcctaca
    36721 attaaccagt tggtacgtaa accacgtaag tctaaagtag aaaaatctaa atcaccagct
    36781 ttgaacgttg gttacaacag ccgtaaaaaa gttcaaacaa acgtttcatc accacaaaaa
    36841 cgcggtgttg caactcgtgt cggaacaatg acacctaaaa aacctaactc agcccttcgt
    36901 aaatttgctc gtgtacgttt gagcaacctt atcgaagtta ctgcttacat cccaggtatc
    36961 ggtcacaact tgcaagaaca cagtgtggtt cttcttcgtg gtggacgtgt aaaagacctt
    37021 ccaggggtac gttaccatat cgttcgtggt gcacttgata ctgctggtgt aaacgatcgt
    37081 aagcaaggcc gttctaaata cggtactaaa cgtccaaaag gctaagaagg gggaaatata
    37141 aatgagtcgt aaaaatcaag cgcctaagcg cgaagtattg ccagatccat tgtataactc
    37201 aaaattggta actcgcttga ttaaccgtgt tatgttggac ggtaaacgtg gtactgctgc
    37261 atcaatcgtt tacggtgcct ttgatcaaat caaagaagca actggtaacg atgcacttga
    37321 agtatttgaa acagcaatgg aaaacatcat gcctgtactt gaagtacgtg cacgtcgtgt
    37381 cggtggttct aactaccaag tcccagttga agttcgtcca gagcgtcgta caacacttgg
    37441 tcttcgttgg ttggtaacaa tcgctcgtaa ccgtggtgag cacactatga tcgatcgcct
    37501 tgcgaaagaa atcatggatg cagcaaacaa cacaggtgca gctgttaaga aacgtgaaga
    37561 tactcacaaa atggcagaag caaaccgcgc attcgcacac ttccgctggt aagataggat
    37621 attttagcgt taaacaaatg ctagccaaaa taggaaaatt gacgcagaaa cttcagtttc
    37681 taggagattt tatctttttg gcagacattt gtagctaaaa ttcaactaag attaagatac
    37741 gagggcgtca agcaactcct agacaaaata gggaagcgaa gcagattgct gtgcaatcaa
    37801 tgaggttcat ctttttgtca gcgagttgta gcccgagttc aattaggatg taaggacgtt
    37861 aagaaaattc aaggaaaaat aggaaatcag acgatggacc ttaaggtcca aggaagattt
    37921 atcttttttc cagaattttt agttcgaact caactaatta agatgtgagg acgttaaatc
    37981 agttctacat aaatcaattg agattatggt agcaacttat cgttcaacca tcacaaatcg
    38041 gattgaggct tgcctcgtcc acttcacacc attagtaaga acttaagcgg gtgggatttg
    38101 cccactcgct tttcttaaaa tatggtataa tcagaataga aatctaaaaa tataggagaa
    38161 caaacctcat ggcacgcgaa ttttcattag aaaaaactcg taatatcggt atcatggcgc
    38221 acgttgacgc gggtaaaaca acgacaactg agcgtattct ttactacact ggtaaaatcc
    38281 acaaaatcgg tgaaactcac gaaggtgcat cgcaaatgga ctggatggag caagagcaag
    38341 agcgtggtat cactatcaca tctgctgcga caacagctca atggaacaac caccgtgtaa
    38401 acatcatcga cacaccagga cacgtggact tcacaatcga agtgcaacgt tcacttcgcg
    38461 ttcttgatgg tgcggtaacc gttcttgact cacagtcagg tgttgagcca caaactgaaa
    38521 cagtatggcg tcaagcaact gaatacggtg ttccacgtat cgtattcgct aacaaaatgg
    38581 ataaaatcgg tgctgacttc ctttactcag taagcacact ccatgagcgt cttcaagcaa
    38641 atgctcatcc aatccaattg ccaatcggtt ctgaagatga gttccgtggt atcatcgact
    38701 tgatcaagat gaaagctgaa atctatacta acgaccttgg tacagatatt cttgaagaag
    38761 atattccagc tgaatacctt gagcaagctg aagaataccg tgaaaaattg gttgaagcag
    38821 ttgctgaaac tgatgaagaa ttgatgatga aataccttga aggtgaagaa atcacaaatg
    38881 acgaattgaa agctgctatc cgtaaagcaa ctatcaacgt tgaattcttc ccagtattgt
    38941 gtggttcagc cttcaaaaac aaaggtgttc agttgatgct tgatgcggtt atcgactacc
    39001 ttccaagccc acttgacatc cctgctatta aaggtgttaa cccagataca gatgctgaag
    39061 aagagcgtca tgcatcagat gaggagccat ttgcagctct tgccttcaag atcatgactg
    39121 acccattcgt aggtcgtttg acattcttcc gtgtatactc aggtgtcctt aacagcggtt
    39181 catacgtatt gaacacttct aaaggtaaac gtgagcgtat tggacgtatc cttcaaatgc
    39241 acgcaaacag ccgtcaagaa attgaaactg tttatgcagg tgacatcgcc gctgcggttg
    39301 gtttgaaaga tactacaact ggtgactcat tgacagatga aaaagcaaaa atcatccttg
    39361 agtcaatcca cgttccagaa ccagttatcc aattgatggt tgagcctaaa tctaaagctg
    39421 accaagacaa gatgggtatt gccctttcta aattggctga agaagatcca acattccgcg
    39481 ttgaaacaaa cgttgaaact ggtgaaacag ttatctctgg tatgggtgag ttgcacttgg
    39541 atgtccttgt tgaccgtatg cgtcgtgaat tcaaggttga agcaaacgta ggtgctcctc
    39601 aagtatcata ccgtgaaaca ttccgcgctt ctacacaagc tcgtggtttc ttcaaacgcc
    39661 agtctggtgg taaaggtcaa ttcggtgacg tttggatcga attcacacca aacgaagaag
    39721 gtaaaggttt cgagttcgag aacgctatcg tcggtggtgt ggttccacgt gaattcatcc
    39781 cagcggttga aaaaggtctc gtagaatcta tggctaacgg tgttcttgct ggttacccaa
    39841 ttgttgacgt taaagctaag ctttacgatg gttcatacca cgatgtcgac tcatctgaaa
    39901 cagccttcaa agtggctgca tctcttgccc ttaaagaagc ggctaaatca gctcaaccaa
    39961 ctatccttga gccaatgatg cttgtaacaa tcactgcacc tgaagataac ctaggtgacg
    40021 ttatgggtca cgttactgca cgtcgtggtc gcgttgatgg tatggaagct cgtggtaaca
    40081 cacagattgt tcgtgcttat gtaccacttg ctgaaatgtt tggttacgca actgttcttc
    40141 gttcagcaac acaaggtcgc ggtactttca tgatggtatt tgaccactac gaagatgtac
    40201 caaaatctgt acaagatgaa atcattaaga aaaacggtgg caatgcataa ttgtctatct
    40261 acacctacct tcgggtaggt gtttttttgg tacgacggat atgtcacaca tctgagcgtg
    40321 atactcatac tcttcgaaaa tcaaaattat ccgttgtcaa cttgccttga tgaactccag
    40381 ttctatcttc ggcttcgttt cctaggctac ttttgatttt cattgagtat cagtagttta
    40441 tctttgattg cttcgacgag cgaggaaact tcgtttcctt atttccaact tcaaacactt
    40501 cactggagta tttgaactcg ctttgtcgta ctttacagaa gtgatttgcg aggcaagtct
    40561 tatttccaac ctagaacagc ctttaggctg ttctagcaac ttgcagctat tgagacgaac
    40621 ttgcttcgcc ctatctccag ccttcaaagg tttcccgaac ctttgaagcg agtactaaaa
    40681 acaaactaaa cgactacact atataaaaca gatatccgcc agattcattt tggaaatata
    40741 caatgagaaa gctacaattt ataaaaaatt accctaattt aggtgtggat ggctaacaaa
    40801 agatcagggt ttgctatttt gggatttcat tgggtataag ttcctgttgt cgatgaactc
    40861 aacagtgact cccaggtccg actactgtga aataaacgga ttaaaacagt ctggggttag
    40921 actatttcag ctcaacaact agaaattagg aattgttgcc gaactctttt gatcgttcga
    40981 gttctcgcct actcacactt aatcagctaa aataaatgtt ttaaattatt tagaattact
    41041 ttgtttggga atggttataa aaaataagag aattaataga taggctacag aagaaaagca
    41101 gatataaatg ttagaatcct tataaggtag atcgatgaaa gagtagttta ggaccgctaa
    41161 ttactaaagg aggatgcttg tatggtgatg aaatagtggt actaagcaca ttaacaataa
    41221 aaagaaagga cagaaaccat gagaaaaaaa ctaaaatttt cattagtagc agtcgcctgt
    41281 gcgacatttt tgacagcctg tggcacaagt aattcctcgg ctcccaaagc aggtgaagca
    41341 acaccacaga cggattttca ttcttatatc aatgcgcaat ggttgaaaaa tacaaaatta
    41401 ggtgccggtg aatcgcaaat agataatctg agtcaactct ctgagaaaac gcaagaagcg
    41461 atacaggaga tgattgacca gctggatatg gactattcca agctgcaagc tggtagtgat
    41521 gagaaaaaac ttattgattt ttaccgattg gcagccgatt ttgatactcg caacaaattg
    41581 gggttagagc ctattaagcc ttatctagag gagattaaaa aagcctctac catggaagaa
    41641 ctcaacaaga ttctggtggc cctatacggc aaaaacatcc gcaatttgct tcatataaac
    41701 gttactcaag atataaaaga cagtaacaaa aacaccatct acgttgaccc tcacgagtta
    41761 agttttccaa aagaaaatta tgatggcaca gatgaatttt cattgaaaaa tcaaaaagcc
    41821 tttaaagcct atctgcagga agtatttagc ttgtcaggag aaacctcaaa agaagcctct
    41881 tctaaggcag atctcctctt taatttggaa aaagagatgg ctgcagtgca acggccaaaa
    41941 gaagaagcca ataactttga agccatgtat aacgagaaga cttgggatga ggtcaaagca
    42001 ctggttccca acctaccgat tgctgagttg gtttctgagt taggacttca gaatgcccca
    42061 acgacagtcg tatcagatcc agatgctcta aaaaatttaa atgaactcta tcaagaaaag
    42121 aatttagacg ctcttaaggc tctgctccaa tatcgtgtga ttgcccatta caatgcttat
    42181 ctgtcaagca atttaatcga ggcaaaagcg aaatacgacg gcgtagcaac cggtgcggta
    42241 gatactccga gtcagaaaga agttgctcaa gcggccattg atgcaaattt ctccgatatg
    42301 attggcaaag tttacgttaa acaccatttt tcagaagaat ccaaggctaa tatcctatct
    42361 atggttcaag agattaaagc gacttatgca gagcgaatca aagcagtgca gtggatgtct
    42421 gaagaaacca agatgcgggc cttgaaaaaa ctagatacat tggttgttaa aatcggctat
    42481 ccagaccagt ggaaggatta ctcacaactt gctatccaat ccaaggaaga aggggggagt
    42541 cttctttcta acttcgatat ggtaaaaaca cttgaattgc gtgaagagat ggggcaattt
    42601 ggcaagcctt ttgataagtc gcagttcggc atgccttctc acacggtgaa tgcctattac
    42661 agcccaacta acaacgaaat tgtctttcca gcggggattt tacaggctcc tctctacgat
    42721 ccaaaagcta gtcccgaaga aaatctaggt ggaatcgggg ctgttatcgg tcatgaaatt
    42781 tcccatgcct ttgataaggc tggttctcaa tttgatgaaa aggggaacct tgtcaactgg
    42841 tggaaaccag aagaccttga aaaatttaat aaaaaggttc aacaggcagc agatatctac
    42901 tctaaattgg aagtggctcc gggctactat gtcaatggcg aaatttcaac cggtgaaatc
    42961 atggcggatc tcggtggttt aacggttgcc attgatattg ctcagaaaaa aggctacgat
    43021 acgaagaaag tcttcgagtc ttatggtaaa gcatggcgtg aagtcaccac caaagaattt
    43081 gctattgcca acatcagcga cgaacatcca ccagctaaat atcgggttaa caacattgtc
    43141 aaccaaattg atcaattcta tacagacttc aatgtcaaag aaggggatcc aatgtatgtg
    43201 aaaccagaag accgcctacg agtgtggtaa aagattatag aggtgtctgc ggtccaaaat
    43261 gggcggtaga caccttttta ggtaaaaaat agaagtagcg gtaaaccaag aatcggtaaa
    43321 aaatgtgtcg aggtatggca atgctattaa gttaagtatt taaccagtca taaccacccg
    43381 agaaaacgca tggctatgat ttttaacttt tattttttgg ccttctattt tttacataag
    43441 atgaaccggt aagcagttgc aattttcggt aaatagttat ataataaaaa cgttgaaaag
    43501 atgcttgtag gcttacaagt taatattttc acaaaaggat taaaaggctt gccttttaaa
    43561 ataaagaact cgattttcat aaggaggaaa tcattcatgg tagttaaagt tggtattaac
    43621 ggtttcggac gtatcggtcg tcttgctttc cgtcgtatcc aaaacgtaga aggtgttgaa
    43681 gttactcgta tcaacgacct tacagatcca gtaatgcttg cacacttgtt gaaatatgac
    43741 acaactcaag gtcgtttcga cggtactgtt gaagttaaag acggtggttt cgaagttaac
    43801 ggtaaattcg ttaaagtttc tgcagagcgc gagccaggaa acatcgactg ggctactgat
    43861 ggcgtagata tcgttttgga agctacaggt ttctttgctt ctaaagaaaa agctgagcaa
    43921 cacatccacg ctaacggtgc taaaaaagtt gttgtcactg ctcctggtgg taacgatgtt
    43981 aagactgttg ttttcaacac taaccacgac atccttgatg gtactgaaac agttatctca
    44041 ggtgcttcat gtactacaaa ctgtttggca ccaatggcta aagctcttca cgatgcattt
    44101 ggcgttcaaa aaggtttgat gactacaatc cacggttaca ctggtgacca aatggttctt
    44161 gacggaccac accgtggtgg tgaccttcgt cgtgcacgtg ctgctgctgc aaacatcgtt
    44221 cctaactcaa ctggtgctgc taaagctatc ggcttggtaa tcccagaatt gaacggtaaa
    44281 cttgacggtg ctgcacaacg tgttccagtt ccaacaggtt ctgtaactga attggttgca
    44341 actcttgaca agaaagtaac tgctgaagaa gtaaacgctg ctatgaaagc tgctgctact
    44401 gaatcatttg gttacactga agaccaactc gtatcttcag atatcgtagg tatctcattc
    44461 ggttcattgt ttgatgcaac tcaaactaaa gttatcgaag ttgatggcga gcaattggtt
    44521 aaagttgttt catggtacga caacgaaatg tcttacactg cacaacttgt tcgtactctt
    44581 gagtacttcg caaaaatcgc taaataatcc ttagtgaaaa tcgaagaggc ttcggcctct
    44641 tttttgtttt gattgctgaa atatagctgt ttccttatgc taagaaacaa ggatggtata
    44701 agttgtttct gatttggcaa ctttagaatt tgaaaaatct gattacgagg cgatagtttt
    44761 tagatttcat aacatttgtg aaaaaaatat ctttatgcaa gaaaaaatac agaaaatatg
    44821 atacaatggt aaagtaaata taatttaagg agttcttatc taatggcaaa attgactgtt
    44881 aaagatgtag aattgaaagg caaaaaagtt cttgttcgtg tggacttcaa cgtgcctttg
    44941 aaagatggcg ttatcactaa cgataaccgt attacagcag ctcttccaac tatcaagtat
    45001 attcttgagc aaggtggacg tgcaattctt ttctctcacc ttggtcgtgt gaaagaagaa
    45061 gctgacaaag aaggtaaatc attggctcct gtagcagctg acttggcggc taaattgggt
    45121 caagacgttg ctttcatcgc aggtgctact cgtggtgctg aattggaagc agctatcaat
    45181 gctttggaag atggacaagt tctccttgtt gaaaacactc gtttcgaaga tgttgatggt
    45241 aagaaagaat ctaaaaacga cgaagaactt ggtaaatact gggcttcact tggtgatggt
    45301 atcttcgtta acgatgcatt tggtactgca caccgttcac acgcatcaaa cgttggtatc
    45361 tcagcaaacg tagaaaaagc agtagctggt ttccttttgg aaaacgaaat tgcttacatc
    45421 caagaagctg ttgaaactcc agagcgccca ttcgtggcaa tccttggcgg ttcaaaagta
    45481 tctgataaga tcggtgttat cgagaacctt cttgaaaaag ctgacaaagt tcttatcggt
    45541 ggtggtatga cttacacatt ctacaaagct caaggtatcg aaatcggtaa ctcacttgta
    45601 gaagaagaca agcttgatgt ggcaaaaaca cttcttgaaa aagcaaatgg taaattaatc
    45661 ttgccagttg actcaaaaga agcaaacgca tttgctggat acactgaagt tcgcgataca
    45721 gacggcgaag cagtttcaga aggcttcctt ggtcttgaca tcggtcctaa gtcaatcgct
    45781 aagtttgacg aagctttgac tggtgcgaaa acagttgttt ggaacggacc tatgggtgta
    45841 tttgaaaacc cagacttcca agctggtaca atcggtgtaa tggacgctat cgtgaaacaa
    45901 ccaggcgtga aatcaattat cggtggtggt gactcagcgg cagctgcgat caaccttggc
    45961 cgtgcagaca agttctcatg gatctcaact ggtggtggtg catcaatgga actcctcgaa
    46021 ggtaaagtgc ttccaggact tgcagctttg actgaaaaat aggcggtaag tcaggaatct
    46081 atgattccgt agacgcaccc ccgcaaggct gaataggttg gtcacaagcg tagcaaagtg
    46141 aactgccatt cagctactgc gtatgaaaga tgaacgatga aaagagttgg gagaccaact
    46201 cttttctagt acaaaggcta gattttctgt gaacgtagtg agtttagaaa atcagcctag
    46261 gtaaaggcta aaatgcaacg gatttccgtt gcattttgtg catcgcgtag agtttctacg
    46321 aagctaagcg agttagaaag tctagcaagg tgtaaagtgc ttccaggact tgcgacggca
    46381 cggagtgcct agtgccatgc ctagtctttc tgggaagtgt gacctagaaa gactggctag
    46441 gtgctgcctt gactgagaaa taggcggtga gtcagttcaa catatctccc agatatgttg
    46501 aggttagaaa tagaagaaac gaagcttctg tcaaaaatga ttccgtagat tgttactttg
    46561 atttttcttg gtgacaactt caaatagtcc actgggctat ttgaaccccg caaggctgaa
    46621 tcttggtcac aactcccatt cagctactgc gctaaaaata taaatgtaaa aaaagacgtt
    46681 gttttttgca gcgtctattt gtttgtctta cttctgggtt ccttcttgca gctgatttaa
    46741 agtggcagat tattggtttt tcgaaaagct ggcgtgaaca ggaggctttt ccagtcgagc
    46801 ttaggagaaa agaaaagctg ggcaggtatt tgctattcta ttttccgaaa tcatgttaga
    46861 atagaggcat gtttaaaaaa tatacatttg atccaaagaa atttcggttg gggatgcgga
    46921 cgttcaaatc gggtttggca gttttcctag ttattctttt gtttggtttt atgggctggc
    46981 aagggattca gattgcggct ttgacggctg tgtttagttt acgagaagac ttcgatcaga
    47041 gtgtccattt tggagcttct cggattctgg gcaattctat tggtggtttt tatgcgctac
    47101 ttttctttat tttggatagg ttattcttag atcatttttg ggtaactgcg gtttttgttc
    47161 cgatatttgt catgttaacg attatgacaa atgtggcgat gaataataaa gcgggaatta
    47221 ttggtggagt atcagcttta ttaattatta cattgtctat tcctgctggt gatacgattc
    47281 aatatgtgtt tattcgtgtg tttgaaacct ttatcggagt tttcattgcg attctagtta
    47341 attatgatgt gaatgttata aaaaaacgtt ttcaggataa atgatgttat aaaatataac
    47401 atcacctatt gacctcaaaa aaaaattctc ctataatggt aggcagaaag gagttcatta
    47461 tgagagaaaa agagtttcgt cgttccttag ctatctttcc gatcggtagt gtgatgaagt
    47521 tgacagattt aactgctcgt caaattcgtt actatgaaga tcaaggcttg attaagcccg
    47581 atcgcaacga agggaatcgt cgcttgtatt ctctaaacga tatggactta cttttagaaa
    47641 tcaaggattt tttggatgaa ggtttgaata ttgctgcgat taagaaggaa tatgcaaatc
    47701 gggaagcgaa agctaaggtc caaaaacagc agaaaacctt gactgatgaa gatgtccgtc
    47761 gtatcttaca tgatgaattc agtcgtcagg gacgattttc aagtcctagt tccattttcc
    47821 gttcgtcgta attagctttt aaaatagagg agaaaaataa tgacattcac agtggcagat
    47881 atcaagcgcg atatcaaaga gaaaaacgtt accttcctac gtcttatgtt tacagacatc
    47941 atgggagtga tgaaaaacgt agaaattcca gcaactgatg agcaggtcga aaaggttttg
    48001 tcaaataagg tcatgtttga tggttcatct attgaaggat ttgttcgtat caatgaatca
    48061 gatatgtatc tttacccaga tttggataca tggactatct tcccttgggg tgatgaaaat
    48121 ggccgtgtag ctggcttgat ttgtgatatt tatacaacag atgctaagcc ttttgctggt
    48181 gacccacgtg gaaatttgaa gaaatcgctt cgtcacatgg aagaggcagg tttctcttca
    48241 ttcaaccttg gtccagaacc agaattcttc ctctttaaga tggacgaaca aggaaatcca
    48301 acgcttgaag taaatgataa aggtggttac tttgacctcg caccaacgga cttggctgat
    48361 aatacacgtc gcgaaatcgt caatgtcttg acagagatgg gctttgaagt tgaagcgagt
    48421 catcacgaag tggcagtagg tcagcatgaa attgacttca aatatgcgga tgtcttaaaa
    48481 gcttgtgaca atattcaaat cttcaagtta gttgttaaaa caattgctcg taagcatggc
    48541 atgtatgcga cctttatggc caagcctaag tttggtattg ctggctcagg tatgcactgt
    48601 aacatgtccc tctttgacaa ggatggaaac aatgccttct ttgatccaga agatcctcgc
    48661 ggtatgcaac tgtctcaaac tgcttaccat ttccttggtg gtttgattaa gcatgcttat
    48721 aactatactg ctattacaaa cccgacagtg aactcttaca agcgtttggt tccaggcttt
    48781 gaagctcctg tgtatattgc ttgggctggt aaaaaccgct caccattggt tcgcgtacct
    48841 gcatcacgtg gaatgggaac tcgtttggaa ttgcgctcgg ttgatccaac tgccaaccca
    48901 tacttagcta tggcagttct attggaagtt ggcttggaag gtattcaaaa taaaattgaa
    48961 gcaccagcac cagtagaatc taatatctat gcaatgtctg atgaggagcg tcgtgaagca
    49021 ggtatcactg atcttccttc aactcttcac aatgcattga aagctcttcg tgaagacgag
    49081 gtagttcgtg cagctctagg tgatcatatc tatacgaatt tcttggaagc taagaaaatc
    49141 gaatgggcaa gctacgcaac ctacgtttct caatgggaaa tcgacaacta tttggatatg
    49201 tattaaacaa aggaccccga cgggtccttt gttcacgagc cgagaaattg gaaatcgggt
    49261 aatggtccag tggagtgaag tggtctggaa agagactgtt tcagtctgag ctaataaata
    49321 gcagggcgag gggatagaca tgagcttgaa atctgtcttt tttcaagctg ggttatcttg
    49381 ttaatataaa ataaatccca gaggtttcac ctctgggatt ttagtgtgtt atcggtcagg
    49441 cgtcagaatc attgggataa tgattggttc acgctctgtt ttttcgtata ggaatggtcg
    49501 tagggcgtta acaatggcgc cgttgactgt ttggatattt gcgtctttgt tgcgcatggc
    49561 gatgcggata gcgttgaaaa ggacgcgttg gctttcgcga atgagctcgc cagattctct
    49621 catatagata aagccacggc tgaggatgtc tggtcctgct aatatcatct tagaattaaa
    49681 atcgacagtg gctactgcaa ggacaacacc atcttctgaa agatcgcggc ggtcttttag
    49741 aacagctgcg ccgatttcac cgatgcggtt tccatcaaca tagatgtctt gggcgttgaa
    49801 ttgacctgcg agacgtgcag aatcttttgt cagagcaagg acatctccgt tttccatgat
    49861 gaagatatta tctttgggaa cgcctgtatc aacagctagg ctggcatgga ttttttgcat
    49921 gcggtattca ccatggacag gcatgaagta tttgggtttg atcaagcgga gcatgagttt
    49981 ttgctcttgt tgaccaccgt gtccagaggt atggatgttg ttgatcttgc cgtgaataac
    50041 atcgacaccg gcttcaatca agatattgat gagcttgttg acacctgtgg tatttcccgg
    50101 aataggactg gacgagaaga taaccgtgtc gcctggctgg agttgcacct gacggtgggt
    50161 accgtgggcg atgcgagaga gtgcggccat aggctcaccc tggctacctg tacagagaat
    50221 catgatctcg ctggcagggt attctttgat ctcgtttggc tcgatgaagg tatccttagg
    50281 caccttgatg tagccgagct cgataccgtt aacaatggct ttttccatgg aacgtccaaa
    50341 gacagcgatc ttgcgtccgg tcttaaccgc tgcatcagcc gcctgttgga gacggaagat
    50401 gttggaggca aaggaagcaa agatgatgcg tccgtgaatg ccttcaatca gcttcataat
    50461 ggactgaccg accacttttt ccgagttggt gaaggttggg acttcagcat ttgtcgagtc
    50521 ggaaaggagg cagagaacgc cttcttcacc cagggcggcc atgcggtgaa ggtctgctgg
    50581 ctcaccaaca ggagtgaagt cgaacttgaa gtcaccggta cagacgattt tcccttgagg
    50641 tgtatcaacg acgataccga gaggttctgg aatggagtgg gtggtacgga agaagctgac
    50701 tttgaggtgc ttgaaggtca actctgtatt atgattgatt tcatgcaaag tcgcatcacg
    50761 gagcagaccg tgttcttcca atttgcctcg aataagggcg agggctaaag gtccagcata
    50821 gattgggaca ttggcctgct tgagtaagaa gggaatgcct ccgatgtggt cttcgtgccc
    50881 gtgggtaata accagacctt taacgcggtc taggttttca acgatgtagg agtagtctgg
    50941 gataacgtag tcgataccca ataggtcatc ttctgggaac ttgataccgg catcgacgat
    51001 gagaatttca tccttatact cgataccgta ggtgtttttc ccgatttctc ccaaaccacc
    51061 gatggcgaaa acgccaactt catgaggttt tagattgact gatgacatgg attaaaactc
    51121 cgtaattttg aaatctgcgt gctctttctc gtattcaaga tgattgtctg ataagaggtc
    51181 gataaattcg atattgtatt cagggcggtt ggtttccacc aattcacgcg cgataatacg
    51241 accttccaat tctgatgcag catcgatgtc tagataaaga gcacgtgtct gctcgcgacg
    51301 tgggctaatt tttgattctt gatagaatac tttataaatc atgtgtagta tagttccttt
    51361 ctttttgact ggcaactatg aaaaaagcct caaacagttg ggtctgtctg gtaatatcta
    51421 ttcaattttc tcgagttgtc aatttattca gtctaaatgt actcttcatt ataccataaa
    51481 atatgctgat ggtaaaaggg tttggtagga aaatggaaaa gtgtcatgat tttcagaaat
    51541 tcggtatttc agaagggtat aaatcaaaga aatgagttag gattccgagt gtgttgggat
    51601 tactaagact aagttcaatt gtgctgagaa atgcctatca actgccagat agtgatgtga
    51661 cttactagaa tgacaaatcg gttcgatcca ttaacctact agaaatcaca ccccagtctt
    51721 ttccattatt tgaaaaaata tccaagatag cttacaatag agagtagcat ttaaaagtct
    51781 ttcagtttgc ttttagtact aggcaacgag ctgcgggctg tactggagta cggcacaggg
    51841 agttcaaaca atacagtgta ttgtttgaag tgggaaatac ggaaacgaag tttcctcaag
    51901 tgttgaagta ataaaagcaa accgaatgac gtaaagaaag agaaacttat gaaaatacta
    51961 gctttggaca gctccaatca ggccttatcg gttgccttgg tggaggacgg tcgtttgcag
    52021 gcggaaaccc tgttggctgt caagaaaaat catagtatca gcctcatgcc tgtggttgat
    52081 tttttggtag cgcaggtggg ctggacaccc aaagacctgg atcggattgt ggtcgctcag
    52141 ggacctggct cctacacggg cctgcgggtg gcggtggcga ccgccaagac cttggcctac
    52201 accctcaaga tcgacttggt ggggctatct agtcttcagt ctctggttcc tcctagcctg
    52261 acgggtctgg tggtgcctct cattgatgcc cgccgtaact gcgtctatgc aggtgtttat
    52321 gaaaatggca gagcagtcga gccagaccgc tactggtctt ttgaagactt gctttctagc
    52381 ctgtctggta aggaaaatat tacctttgtc ggagaagtag aaaactttat ggagcaaatc
    52441 gaacaagctc taccgactgc tcagtatcaa gctagtctgc cgtctgccta tcagctagca
    52501 gtaatcggtc aagacttgcc agcagtagat gtgacgagct ttgagcccaa ctatctcaag
    52561 catgtagagg cagaagaaaa ctggctcaag gacaaccaag ttggctcaga aagttatatc
    52621 aagcgtgtat gatagagatt aaacactacg acggtcagga aaatctggcg gaggctgtgt
    52681 tggcagttat gcagtccgtc tatgatcagt caccttggac cttggaacag attgtttcaa
    52741 gcatgaccag tcagtatgag gattattatt tggcctatga gggtcaggaa ttggtcggat
    52801 ttttggctgt gcagacggtg ctggatgaga tggaaatctt gcagattgct gtcaagactg
    52861 attttcagag gctgggaatc gccagtcaac tgatggctgc tgtgatggac tgggatgggg
    52921 atattttcct cgaagtgaga gagtccaata gcgcagctca ggccctctat acacgccagc
    52981 attttaccaa aataggaaaa cgaaaagact actaccgcca tcctgtcgag gacgcggtga
    53041 taatgaagag agaacgtgat gaaagataga ttgattttgg cgatcgagac ctcctgtgac
    53101 gagacctcgg tggctgtttt gcgaaatgac gcggagcttt tatccaacgt cattgccagc
    53161 cagattgcca gccaccagcg gtttggtggg gtggtgcccg aggtggccag ccgtcaccat
    53221 gtggaagtga taacggcctg tatcgaggag gccttgttgg aggcggaagt gacggcagag
    53281 gacctgacgg ctgtggctgt gacctatggg cctggcttag ttggtgccct gttggtcggg
    53341 atttcagctg ctaaggcctt tgcctgggct aacggtctgc cgctcattcc tgtcaaccac
    53401 atggcagggc atttgatggc ggcgcgggcg gtcaaggagt tggagtttcc gctcttggct
    53461 cttttggtca gcggtgggca cacggagttg gtctatgtgt cagaggcagg tgactacaag
    53521 attgtcggtg aaacgcgaga tgatgcggtc ggcgaagcct atgataaggt gggtcgggtc
    53581 atgggcctgc cctatccagc tggtcgggtg attgacgaat tggcacatga ggggcaagac
    53641 atttatgact tccctcgggc tatgattaaa gaggataatt tggagttttc tttctctggt
    53701 ttgaaatccg cctttatcaa cctctaccac aatgcccagc agaaagggga gaccttgtcc
    53761 aatgcggact tgtcagcctc tttccaagcc tgtgttatgg acattctcat ggctaagacc
    53821 aagaaggcct tggagcaata ccctgtcaaa accttggtgg tagcgggcgg tgtggcagct
    53881 aatcagggct tgcgagagcg gttggctgct gaaattaccg atgtggaggt tatcattccc
    53941 ccgcttcgcc tctgcggtga caatgcaggt atgattgcct tagcagcggt cagtgagtac
    54001 aataaggaaa accttgctgg ctgggacctc aatgccaagc ctagtctggc ttttgagaat
    54061 ttatagaata aaaacctctt acgtcaagga tacgtaagag gtttatttgt ggatttttcg
    54121 ccagcgattt ggagaaattt ggtaatgtct tttaaaagca gttgaaaaat tgaattggtt
    54181 ggagtagccg atttcttcag caatttcctg tagtgtctta gtagtgtttt ttaagagttc
    54241 gcaggcttcg ctgagtcggt attggatgat aaattgttga ggtgagatgt tcatttgctc
    54301 cttgaatagc cgactgaagt agtggcgatt gaggttgcac acttgtgcca aatcatcgac
    54361 ggatatagct ttctcataat ttcgttctac gaagttgata gcttctcgta tataaaattc
    54421 cttgttttca tcgtgtttgc tacttgtttt ggttagcgaa cagtcaatga ggcaggagat
    54481 aaagaggtaa aggtgtccga gaactagagc gcttttttga tgatggagcg cgagaatttg
    54541 tttcatttca tggtagacag ggctagaggt gggcatttct cgttgtgaaa agataggttg
    54601 ttctttcgag agccctgcct gtctgagaaa atgctcagtt ttcagaccgt caaattcaag
    54661 ccagatatag gtccaggggt ccttttcgtc tgcttcgtag ctacagatgg cgtctgggga
    54721 gataaggaag ccctgtcctg cggttaggtg gtattcacgt tggtcggagg tatcgtaaaa
    54781 agtacctgaa ccagagatga tgtagtgaaa caggtagtgt tgtttcatag ttgggccgaa
    54841 tgagtgaagt ggcttacagg cttccatgcc aaattggatg gggtaaaaat ctacatagga
    54901 tctgttatta aagacgtaaa attcaggttg tattttcatc gtattctcca taccaaaagt
    54961 gtaaaggctt
//
LOCUS       DBNFCO010000004        52979 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.004, whole genome shotgun sequence.
ACCESSION   DBNFCO010000004 DBNFCO010000000
VERSION     DBNFCO010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 52979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52979
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.004"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            <1..1268
                     /locus_tag="AC1PIV_000199"
     CDS             <1..1268
                     /locus_tag="AC1PIV_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HIP6611255.1"
                     /translation="RLIHNKLFLSSFVADLISNFGDTLYYLALMNYVLLLPDTKFALA
                     MITASETLPILAGLFIGIWADKTKNKLDTILATLVVRVGLYAFVGFLMGFAPALWVVA
                     VVCVINFLSDLAGQYENGLYMPVSLRVVAAEDRETAMAFKMTVKSLLQIAFQASGAIL
                     IGFMSYQNLAFFNAGTFLVSLAIMATLRPALAKLLKENPIQEAEQTETEAGIIKGMRN
                     SLKESYQAVQNIPVLKASIVTIASLNAIFTALSPLVILNMKEFSDFVIVNAGTTVALI
                     SIFFSVGSILGSSIGMALFKNVSLINLLKFSTLMPVLIFSGFFLHNIYVVLTIIFVTA
                     MTLGVFNPKMNALVLNELPEDKLATVGGGIDAFCQIGMVAGQALVALMVTVLSATSIS
                     LIFLLLSVGLVSYTILVGRKSKNEVVVKA"
     gene            1280..2320
                     /locus_tag="AC1PIV_000200"
     CDS             1280..2320
                     /locus_tag="AC1PIV_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009910042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR/SmtB family transcription factor"
                     /protein_id="HIP6611256.1"
                     /translation="MKLDYRDYRSEIVEKFFIPLIVKEREEPIEADFSQKEKGILKDT
                     LDIRDEIEEKLADFRQEVNQVFVWGYIFNILHSLYFYILNDGQDPKTVEEACQLILKL
                     SQEEVEDAMRTMLASENDGHREKTLSLMELLEKTDKKPADKWYWSLAIRNPLETVERS
                     VHLLDKMLPIYQPYFEQARVEREAFARDFDIEKLYRDSKQLSMTGLDALSVENAQFFV
                     LSPWNYWFAYYGNEEFDYMKVALLASCRIDQIMLSNDELDLDDLTTALKVISDSTRYQ
                     VLVELTKPHAKSKDIAERLAITGAAVSFHTQKLINGDLLLFNTKNSDVKYSVNRELLQ
                     EVIAKLTEDFDL"
     gene            complement(2566..3555)
                     /locus_tag="AC1PIV_000201"
     CDS             complement(2566..3555)
                     /locus_tag="AC1PIV_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HIP6611257.1"
                     /translation="MQNKTKPLNTSLLSLIQFIGAILVIALHCRRLFETDQLHFIQKS
                     IFSRMVVPYFMVTASFFLRRNYPSLSKQYLIRYSKQYLTWSVLYLPFYLFYLNLQEIP
                     LLHYPLALLVGLTYTGTSYQLWYMPAFLLGLVLVHYSLRKWGWRITACLACLLYLLGS
                     VETYSSYLAESIFLTAFDSYKTFFFTSRNGLFYAPIFLLTGFYLADKLNHPIFQYRQK
                     NKLLVCTALLAFEATVIYLKQGYDKNFLFSLIPFTAYLVAWTLTTDLFRQKKFQFLKE
                     YASYYYFIHVIPVEISFFFLENHSLTIIQQGWLVFFITIITCQLLSWLIINTQ"
     gene            3744..4430
                     /gene="rnc"
                     /locus_tag="AC1PIV_000202"
     CDS             3744..4430
                     /gene="rnc"
                     /locus_tag="AC1PIV_000202"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HIP6611258.1"
                     /translation="MKDLHAKLLADFGIDFSDLNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLMISKYLYQKYPDRPEGEMSKLRSTFVREESLAGFSRACGFDRFLRL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKGEKTVEEFIHKVMIPRLEKGNFERVTD
                     YKTALQEILQVNGEIAISYQVIAESGPAHDKTFEVEVSADQRVIGHGRGRSKKLAEQA
                     AAKNAVEARG"
     gene            4433..7966
                     /gene="smc"
                     /locus_tag="AC1PIV_000203"
     CDS             4433..7966
                     /gene="smc"
                     /locus_tag="AC1PIV_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HIP6611259.1"
                     /translation="MYLKSIEMQGFKSFADKTKVVFDRGVTAVVGPNGSGKSNITESL
                     RWALGESSAKSLRGGKMPDVIFSGTESRKALNYASVVVTLDNSTGFIANKQKEIKVER
                     HIYRSGDSEYLIDGQKVRLRDIHDLFMDTGLGRDSFSIISQGRVEAIFNSKPEERRAI
                     FEEAAGVLKYKTRKKETESKLAQAQDNLDRLDDIIYELDNQVKPLEKQAQTAKKFLEL
                     DGQRKELYLNVLVAQLSLGKEKLSEKEAELESVKTELTSYYKQRSELEQENLNLKEKR
                     HRLSEQLEREQAVLLDLTKLISDLERKIEVHKLESSQNESSHQEAQARLENLLTRREQ
                     LAEQIEQKQETLAQLDSSLSSLKDDIAAVDKEISYFSEDPDQVLDHLREQYVALMQEE
                     AEASNSLTKIQQDIANQISLSESKSEDLARLQTEKQTAQEVLDKSRKSLEEADHVLRQ
                     LLESYQTKKTELDQVQTAYQAEQGRLFDLLDQLKGKQARQSSLEAILKNHSNFYAGVK
                     AVLQAAPSLGGIIGAVSEQLTFDTRYQTALEIALGGASQNVIVEDEATAKRAIAFLKE
                     KRQGRATFLPLTTIKPRQLSGQQVSLLESSEGFLGLASDLVTYQPNLDAIFQNLLGTI
                     AIFDSIDHANQAARATKFQVRMVTMDGAEIRPGGAFAGGSNRNNSTTFIKPELDALLG
                     EIAELSSQLQEQESLVAAKKTSLDQTREALETIKAEGEEARLNQQSARIHQEQAENRL
                     AQLSAQYDLQMSQVSPTILTELEEAAAKEEVNVQALNEKKLALDQQINQVRDNRDSIQ
                     ESLQKLQTQKGQLTLEQAELTSQLRFEQTDLRRLQEEKVVADKEISLLEDMIDQKLEA
                     LEDTSIEILEEQLQAASDKQNQTNQILIRLKFELEDIDGQFEDLEERLQQARTKNDDL
                     IRKQAKLEADCEQAGDKLRTLLGNLTEHFKLSFEAAQSQAKEVENLAVAEQSLKDLER
                     AIRALGPVNLDAIEQYDEVNNRLTFLNEQRTDILSARDLLLDTIHEMDDEVKERFKVT
                     FEAIRESFKQTFKQMFGGGSADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKESQFIVVTHRKGT
                     MAAADAMYGVTMQESGVSKIVSVKLKDVEKL"
     gene            7963..8772
                     /locus_tag="AC1PIV_000204"
     CDS             7963..8772
                     /locus_tag="AC1PIV_000204"
                     /EC_number="3.-.-.-"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HIP6611260.1"
                     /translation="MINKIYASDMDGTFLREDHSFDKERFRRILNQFKEKGYLFVAAS
                     GRSMQSLKLVFEDFVDEIGFVAENGSIVEYQGQTIFMDDPISPEIYLPIIAGIDAGPF
                     GSSRSMVLSGLENFYLLKNAEPQFLEAMTNYYAHFRLVDTFEEVREEIIKINAKFSPE
                     EMDDARRWLNDTFEGVTAMTTGFDNIDIIPNGSNKSVGLSHLCAHFGITRQDVVAFGD
                     NQNDLDMFDFAGLALATENAREEVKAQADWMIGHCNDGAVLAYLEEEVNGN"
     gene            8762..9574
                     /locus_tag="AC1PIV_000205"
     CDS             8762..9574
                     /locus_tag="AC1PIV_000205"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HIP6611261.1"
                     /translation="MAIKLIALDLDGTLLTSDKRISEANKKALQAARERGVYVVLTTG
                     RPLQAIGTFLEELDLLGENQYSITFNGGLVQENTGRVLDKVGFTIEDVRTIRRVTNDL
                     DLPLDVLYGGDVYSLPSAHESLYLTCNPLLNKIVASDEEMPEDFVYNKAVSAVAADFL
                     DGQIPKIPAELHERFEIFKSRDILLEWSPKGVHKANGLAKLIGHLGIDQSEVMACGDE
                     GNDLSMIEWAGLGVAMANATDEIKSAANLVLPKNNDEDGIAWVIEHYVLNED"
     gene            9576..10850
                     /gene="ftsY"
                     /locus_tag="AC1PIV_000206"
     CDS             9576..10850
                     /gene="ftsY"
                     /locus_tag="AC1PIV_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HIP6611262.1"
                     /translation="MGLFDRLFGQKKQEEQVALVEEVEREQSASSEDTVTTEVESATQ
                     EMEKFQSEVAETELTAEQEAQKQRTLDMMAQYYAAKEAAAARVKEAQEQGFDPAIQTK
                     VKEEPVEEVAPVGQESEQDKYQRTLKKTRTGFGARLNEFFANFRSVDEEFFEELEEML
                     ILSDVGVQVASTLTEELRYEAKLQNAKKIDELRRVIIEKLVDIYEKDGQFSEQINFQD
                     DLTVMLFVGVNGVGKTTSIGKLAYKYKQAGKKVMLVAADTFRAGAVAQLVEWGRRVDV
                     PVVTGPEKSDPASVVFDGVKRAVAEGVDILMIDTAGRLQNKENLMAELEKIGRIIKRT
                     LPDAPHETLLALDASTGQNALSQAKEFAKITPLTGLVLTKLDGTAKGGVVLAIRQELD
                     IPVKLIGFGEKIDDIGEFKSEEFMRGLLEGLV"
     gene            complement(10874..11431)
                     /locus_tag="AC1PIV_000207"
     CDS             complement(10874..11431)
                     /locus_tag="AC1PIV_000207"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIP6611263.1"
                     /translation="MQHKGTQILETERLILRPFQASDVESVFQNWTSDEKVTTYLTWP
                     THQTLQDTEDYVQFCLQSYSQEKTYRWVIELKENQQPIGDISVVSLDERVQAAELGWV
                     LGSKWWGQSYMAEALEAVNHYLLEEVGCLRITAVHDSENRPSGRVMEKVGMTYEGTLR
                     QAARNNRGIVDIAIYSLLHTDRKSR"
     gene            complement(11433..12107)
                     /locus_tag="AC1PIV_000208"
     CDS             complement(11433..12107)
                     /locus_tag="AC1PIV_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HIP6611264.1"
                     /translation="MTEMNIILTQLEVASHAGTLKRYEKIGETKPYYGVPMGAISGIA
                     KAYKNRLDLFAPLWQTGVLEAQYLAIQVAKAKPNQLPQADLENCLNEQISVNVLDKLA
                     SIILSKRKDSKDWEEYLLIQDQAIFQRLGWFLRAKYFAGRTASNQEIEESLDHIRQHL
                     QTADPLVQWTMNQCLVEIAVTYPDYLEQGLAIGQELAVYANMKVPKGCTSAYAPDWIE
                     ALLRRK"
     gene            complement(12307..13794)
                     /gene="zwf"
                     /locus_tag="AC1PIV_000209"
     CDS             complement(12307..13794)
                     /gene="zwf"
                     /locus_tag="AC1PIV_000209"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004345 - glucose-6-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HIP6611265.1"
                     /translation="MSSHVLFTIFGASGDLAKRKLYPSLFRLYKAGHIRENFAVIGTA
                     RRPWTKEFFEQTVIESLGDLPDTPRQAHEFANHFYYQSHDVNDTEHYVALRKLQDDLC
                     EKYNTQHNKVFFLSMAPEFFGTIAKHLKSEQIVDGQGFERLIIEKPFGTSLATATKLN
                     DELAAAFNEDQIYRIDHYLGKEMVQNIFAVRFANIIFEHIWNRDYIDNVQITFAEAIG
                     VEDRGGYYDHSGALKDMVQNHALQVLSLLAMDKPASFKEEDVRAEKIKVFQHLRQPSD
                     EDLKRNFIRGQYAAGSIDGKDYVSYLDEPNIAEGSQTETFAGGVFFVDTDRFRDVPFF
                     FRTGKRLTEKGTRVTITFKHAEDIFGQPSEANVLTIFIQPTEGFMLSINGKEVGSHFA
                     LTPAKLNFRHNATALGNSPEAYEKLFFDVLNGDSTNFSHWEEVKASWSLIDRIVDLWA
                     SNQVPLHTYPAGTMGPEAAFDLLESYSCKWVWTPDVWYRERGLLK"
     gene            complement(13873..14688)
                     /locus_tag="AC1PIV_000210"
     CDS             complement(13873..14688)
                     /locus_tag="AC1PIV_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family putative permease subunit"
                     /protein_id="HIP6611266.1"
                     /translation="MIRFLILAGYFEMTMYLYISGKLDQYINLHYSYLAYLSMVLSFI
                     LAIVQLYVWVKEIRVHSHLKSKIAKLSSIGLLLIPLAIAWLFPTVSLDSTTVAAKGYH
                     FPLATENDTNTQNQEGATVQYLKPDTSIYFTKSAYQNQMREIADRYLAEETIVVTNEN
                     YMEVMEAIYDYPTEFSGKTIEMIGFVYNDPDNSQQFFLFRFGIIHCIADSGVYGLLST
                     GATTEFPNNTWVKARGTIKVSYHTSLKQNLPTLELQSMVQIEQPDSPYVYRVF"
     gene            complement(14685..15590)
                     /locus_tag="AC1PIV_000211"
     CDS             complement(14685..15590)
                     /locus_tag="AC1PIV_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HIP6611267.1"
                     /translation="MLGLDQLPTSVLQAGAIFLSIMIEALPFVLIGAIISGFIDVFIT
                     PDKVRKLLPKNKFLAILFGTFIGFIFPSCECGIVPIVNRLLEKKVPSYTAVPFLVTAP
                     VINPIVLFATFTAFGNSLLFALYRALGAIIVSLVLGIILGFFVKGPILKGSKFDHHQH
                     DYSDKTSWQKVGFALIHAIDEFFDTGRYLVFGCLFASLVQVYIPTAVLTTIGHSPLTA
                     ILLMMLLAFLLSLCSEADAFIGASLLSSFGFAPVMAFLVIGPMVDVKNLLMMKHYFKG
                     KFIVGFIITITLVILGYSLILGGVV"
     gene            complement(15592..15738)
                     /locus_tag="AC1PIV_000212"
     CDS             complement(15592..15738)
                     /locus_tag="AC1PIV_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPJ_0845 family protein"
                     /protein_id="HIP6611268.1"
                     /translation="MAVTYKRQDDLEKMLEEFASFEKLEEIEYPDPKSKEHSEKNNLN
                     QDKK"
     gene            15861..17819
                     /gene="ligA"
                     /locus_tag="AC1PIV_000213"
     CDS             15861..17819
                     /gene="ligA"
                     /locus_tag="AC1PIV_000213"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011837172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HIP6611269.1"
                     /translation="MKTRISELVSVLNQYAKEYYQLDQPSVSDAEYDTLYRELVELET
                     AHPELILPDSPTHRVGGKMLDGFEKYSHVYPLFSLQDAFSREELEAFDQRVRKEFPQA
                     TYICELKIDGLSISLTYEAGNLVVGATRGDGSVGENITENLKRVADVPLTLPEAVDIT
                     VRGECYMPKASFDRVNKQRQEAGEAEFVNPRNAAAGTLRQLDTGVVAQRGLATFLYQE
                     ASPSEATSQSQVLEKLDALGFVTNHEYCLAESIDDTWDFIEKIAERRDDLPYEIDGVV
                     IKVNDLAIQEELGFTVKAPRWAVAYKFPAEEKEAEILSVDWTVGRTGVVTPTANLSPV
                     QLAGTTVSRATLHNVDYIAEKDIRIGDTVIVYKAGDIIPAVLKVVDKYRKEQEIMPIP
                     SHCPSCQSDLQHYEDEVALRCINPICPSQLMSKLEHFASRDAMNIAGLGSSIVEKLFG
                     AGLVHDVADIYKLTVDDLLTLEGFKEKSANKLYQAIQTSKSNSAECLLFGLGIRHVGS
                     KASKILVEKFGDLETLAFADQEAIASLEGLGQVIAKSLTTFFASEGAQQLLAELKEAK
                     VNLTYLGQVVDENAALSGMTVVLTGKLERMKRNEAKAKLEALGANVAGSVSKKTNLVV
                     AGTDAGSKLTKAQELGIEIKDEAWLESL"
     gene            17830..18873
                     /locus_tag="AC1PIV_000214"
     CDS             17830..18873
                     /locus_tag="AC1PIV_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HIP6611270.1"
                     /translation="MEERKRARLIYNPTSGQEIMKKNVAEVLEILEGYGYETSAFQTT
                     AEKDSAKNEATRAALAGFDLIIAAGGDGTINEVVNGIAPLEKRPQMAIIPTGTTNDYA
                     RALKVPRGNPVEAAKVIGKQQTILMDIGLAKNQKNGFHQEHYFINIAAAGTLTELTYS
                     VPSQLKTMFGYLAYVVKGAELLPQVQFTPVRVEHDEGVFEGSVSMIFVALTNSIGGFE
                     QIVPDAKLDDGNFTLLMVKTGNLFEILHLIRQVLDGGKHIESDLVEYIKTKSLSIENL
                     NPDNRLLLNLDGEFGGEAPVRLYNLSNHIEFFADTDLVSDHAITLDTDQMNREDMAKR
                     FIEETDHIDEAIK"
     gene            19010..19210
                     /locus_tag="AC1PIV_000215"
     CDS             19010..19210
                     /locus_tag="AC1PIV_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HIP6611271.1"
                     /translation="MSLGALALGLACLGVSIGEGLLVASYLSSTARQPEMQSKLMAGV
                     FLGVAFIEGTFFVTLAMTFVLK"
     gene            19247..19963
                     /gene="atpB"
                     /locus_tag="AC1PIV_000216"
     CDS             19247..19963
                     /gene="atpB"
                     /locus_tag="AC1PIV_000216"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HIP6611272.1"
                     /translation="MEEHLSPTLTLGPVTFDLTMVLVSVITISIIFLRVFWASRRMEL
                     KPKGKQNVLEYVYELTINFTKGNLGDAEAKRYSLFFFTVFTFLLVANNLGLMTKLETA
                     EGHNLWTSPTANMAYDFGLATIATVFCHVEGIRRRGFKAYLKSFVTPWAMAPMNILEE
                     VTNLVSLALRLYGNIYAGEVLVSLLLQLSQQSALAYPIAFALNVVWTAFSVFISCLQG
                     YVFIMLVSMYLNKKISSESE"
     gene            19981..20487
                     /gene="atpF"
                     /locus_tag="AC1PIV_000217"
     CDS             19981..20487
                     /gene="atpF"
                     /locus_tag="AC1PIV_000217"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045259 - proton-transporting ATP
                     synthase complex [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HIP6611273.1"
                     /translation="MATTITMQSSTILGNFILVTASFAVLIILIRVFAWDKITGIFEE
                     RANKIANDIDAAEEKLTAAANLVQQREDELVQGRIESQKIIQDAVERAKLEKKRILEQ
                     ADVEIQGLKQKAQLEIEAEKREAQENLRVQVAELAVDLASKIILEDLDQQAHSNLIDR
                     YLDKLGDK"
     gene            20488..21021
                     /locus_tag="AC1PIV_000218"
     CDS             20488..21021
                     /locus_tag="AC1PIV_000218"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HIP6611274.1"
                     /translation="MNARENAIVQKYALSFVEKVSDHADIWDMYDQISDLISIIHDSK
                     LNRILLSATVSREEKADFVRTVRQSSFWQINDLIEDVIRDGHADLLLETLERVQLQIS
                     KFKNEFEARVVSVYPLTEAQKERLRHLVEQRFSLRVRNITEELDQSLLGGFIVTVNHK
                     VIDASVRTQLKDIRKKL"
     gene            21025..22545
                     /gene="atpA"
                     /locus_tag="AC1PIV_000219"
     CDS             21025..22545
                     /gene="atpA"
                     /locus_tag="AC1PIV_000219"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045259 - proton-transporting ATP
                     synthase complex [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HIP6611275.1"
                     /translation="MESGVLLINAQEISALLKQQIEGFQPDFDYTETGVVTYIGDGIA
                     RAQGLDNAMSGELLVFENGTIGMAQNLETNDVGIIILGQFTDIREGSVVRRTGKIMEV
                     PVGSALIGRVINPLGQPVDGLGEIRTSKTRPIEYPAPGVMQRKSVNEPLQTGLKAIDA
                     LVPIGRGQRELIIGDRQTGKTSVAIDAILNQKGQDMICIYVAIGQKESTVRTQVETLR
                     QYGALDYTIVVTASASQPSPLLFLAPYAGVAMAEEFMYEGKHVLIVYDDLSKQAVAYR
                     ELSLLLRRPPGREAYPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAY
                     IATNVISITDGQIFLKDDLFNSGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLA
                     SYRELEAFTQFGSDLDAATQAKLNRGRRTVEVLKQPLHKPLPVEKQVLILYALTNGFL
                     DSVPIDDILAFEEELYAYFDLHYDGLLDVIRTTKDLPDTDELNAAIQAFKDQSVFK"
     gene            22557..23435
                     /locus_tag="AC1PIV_000220"
     CDS             22557..23435
                     /locus_tag="AC1PIV_000220"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000301235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045259 - proton-transporting ATP
                     synthase complex [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HIP6611276.1"
                     /translation="MAGSLNEIKSKIASTKKTSQITGAMQMVSASKLAKSEQLAQSFQ
                     IYASKVRQITTDLLRGELMASDTSNPMLIRRPVQKSGYIVITSDSGLKGSYNSSILKA
                     VMGMIEQDHDSKDEYEIIAIGSMGADFFRARGINPVFELRGLADNPSFEEVQKIISKS
                     VEMYKNELFDELYVCYNHHVNSLTSQVRVQQMLPVEDLDHNEADGYTATFELEPNREV
                     ILEQLLTQYAESTIYGAILDAKTAENAAGMTAMQTATDNAKNVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            23455..24861
                     /gene="atpD"
                     /locus_tag="AC1PIV_000221"
     CDS             23455..24861
                     /gene="atpD"
                     /locus_tag="AC1PIV_000221"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045259 - proton-transporting ATP
                     synthase complex [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HIP6611277.1"
                     /translation="MSSGKITQVVGPVVDVAFAAEDKLPEINNALVVYKNDDSKQKVV
                     LEVALELGDGVVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EESFPADFEREPIHKKAPAFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLTQ
                     LGIYPAVDPLASSSRALAPQIVGEEHYAVAMEVKRVLQRYQELQDIIAILGMDELSDE
                     EKTLVGRARRIQFFLSQNFNVAEQFTGMPGSYVPVAETVKGFKEILDGKHDHLPEDAF
                     RNVGSIEDVVAKAAKMKF"
     gene            24871..25287
                     /locus_tag="AC1PIV_000222"
     CDS             24871..25287
                     /locus_tag="AC1PIV_000222"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045259 - proton-transporting ATP
                     synthase complex [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HIP6611278.1"
                     /translation="MGQMTVQIVTPDGIKYDHHAAFVLVKTVDGEMGVYSGHEELIAV
                     LEIGEMKVRRVDDENHVDWIAVNGGIIEVNKDIITVISDSAERERDIDISRAERAKLR
                     AERELEEAQTARNIDMEMRATVALQRAINRIRVGKH"
     gene            25347..25571
                     /locus_tag="AC1PIV_000223"
     CDS             25347..25571
                     /locus_tag="AC1PIV_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 family protein"
                     /protein_id="HIP6611279.1"
                     /translation="MVISILQFFSHILFIYLAHHLLVTTVDWSRWLKVTGDNQRKINL
                     LILFLAIALGYLVSTFFLELLMMGRSFANM"
     gene            25595..26878
                     /gene="murA"
                     /locus_tag="AC1PIV_000224"
     CDS             25595..26878
                     /gene="murA"
                     /locus_tag="AC1PIV_000224"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HIP6611280.1"
                     /translation="MDTIIITGSKNGLKGQVEIEGAKNAVLPLLAATVLASQGQTKLT
                     QVPILSDVYTMNNVVRGLGVRVKFDEETKTIDIDATGKLGSETPYKYVSQMRASIVIL
                     GPILARNGYAKVSMPGGCTIGSRPIDLHLKGLQAMGAKIKQRAGYIEASAENLQGAHI
                     YLDFPSVGATQNLMMAATLAQGTTVLENAAREPEIVDLAIFLNKMGAKVKGAGTETIT
                     ITGVEELTGAEHQVVQDRIEAGTFMVAAAMTGGDVLVKDAVWEHNRPLISKMLEMGVE
                     VTEEAEGIRVRSQVDKLKPVTVKTLPHPGFPTDMQAQFTALMAVAKGESTMIETVFEN
                     RFQHLEEMRRMDLHSEILRDTAIITGGLALQGAQVMSTDLRASAALILAGLVAEGETI
                     VGKLTHLDRGYYRFHEKLAALGATIERVSGEDENG"
     gene            26871..27062
                     /locus_tag="AC1PIV_000225"
     CDS             26871..27062
                     /locus_tag="AC1PIV_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HIP6611281.1"
                     /translation="MDKDNLSYVGKNLILVAVVLLIAILVFILGLMVGYGVIGDGDNV
                     FAVLSPAKWQELIGKFTGK"
     gene            27092..27931
                     /locus_tag="AC1PIV_000226"
     CDS             27092..27931
                     /locus_tag="AC1PIV_000226"
                     /EC_number="3.1.30.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HIP6611282.1"
                     /translation="MAKKNVKKQAMSLLSLLATIVVVAGGYLLSDNKSSNVADYSYYV
                     NQSKASEGTPNQELASSVLTEDVKKQLGNSIEWNSAGAFIINGNQTDLDASVASVPYG
                     DNKTKTVQGETVPTVANALLAKSTRQYKDREETGNGRTSWTPAGWHQIHDLTGEYDHA
                     VDRGHLLGYALIGGLSGFDASTSNPKNIAVQTAWSNQANDQTSTGQNYFESQIRRALD
                     KNKRVRYRVTLVYAESEDLVPVGSHLEAKAADGSLEFNVFVPNVQSGLSINYHSGEIA
                     VNQ"
     gene            28118..29671
                     /locus_tag="AC1PIV_000227"
     CDS             28118..29671
                     /locus_tag="AC1PIV_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HIP6611283.1"
                     /translation="MEKHVEQRVEDVTYNKAKLWQIILFAMNNSSTNIYLVAFTFVTY
                     LSTGVLGLAALFVSQLMGYIRIFDGFIDPTIGVIIDKTDTKFGKYRPILVLGNIITAA
                     SLFMMLGLSGVSESLRLPLFILVLIIHKIGYSLQQTITKAGQVALTNDPKQRPIFNIV
                     DGIATTVLMTGSQVVVSGTLVPKHGGFTRSFFQELFLGVVVISAVLGILAVIGIWEKD
                     NKKYFGLGEKTQETKLKDYWKVIKGNKPLQVLSISAAFVKFVAQLFGDSVIRVMLYGI
                     IFGDYALSGKMSMLLILPGILVTVGAAQLARRKGLRFAYITALQLGIAGLVTLAAMLF
                     SAKPGMLDLTNWNLYTIGFFVVYIIARYASSAPSGLVLTMGADITDYETSVSGRYLSG
                     MIGTIFSLTDSIASSFAPMVVGFVLAGIGFGKEYPTVETAFSTDLRMALIVLLTVIPA
                     VVLSVSLFLMKFYKLDREEMARIQEKIHVMKAAKDEERVRAIAKNVPLSDMDYVDVTQ
                     YKVDQYDDK"
     gene            29727..30755
                     /locus_tag="AC1PIV_000228"
     CDS             29727..30755
                     /locus_tag="AC1PIV_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PfkB family carbohydrate kinase"
                     /protein_id="HIP6611284.1"
                     /translation="MKKILAFGEVLLRLSPPHYQTLTQATSLDCQFGGSELNVLASLA
                     QLGHSVELVTALPENEVGKMAEHFLFARQIGQKHLIRKKGRLGIYYYQKGFSLRPSQV
                     TYDRDYSAFSLSKEEEYDLEGMFDGVDWFHVSGITVALNPDIYRLAFRLMEMAKRQGV
                     KVSFDLNYRESLWSSFEEAREKLSPFVGLADICFGLEPIQLFNESGKDVKDELGLKRP
                     YENKEVLLAVVKGLAETYSLQSLAFTQREMTYNNEYLLKAYLYQDGILYETEKESIQV
                     LDRVGTGDAFTAGIILGYLQEKTPQEIVDLGMASFQFKHTIEGDVNVISPSDIALLLK
                     KGSREIKR"
     gene            30771..32570
                     /gene="uidA"
                     /locus_tag="AC1PIV_000229"
     CDS             30771..32570
                     /gene="uidA"
                     /locus_tag="AC1PIV_000229"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HIP6611285.1"
                     /translation="MLYPIQTKTRSVYSLNGIWKFKQGNNDVHTLLDTDEVMVVPSSF
                     NDVVVDKDKRRFVGDNWYELMVALPVVADDEELVVRFGSVTHQAKVYADGQLIREHKG
                     GFTPFECLIPSNLYDADQFRLTVCANNELNYTTLPVGNYSEEVDENGQIVKTVKENFD
                     FFNYAGIQRTVHLYKRPQNRIEDIVIRTELNQDLTQAVVNVDVKTVGQYDSIRMSILD
                     QEGQEVGLLENGQMVIEHPRLWEVLDAYLYTAKVELVDGENLLDTYSEQFGIRSVAVE
                     NGQFFINGKPFYFKGFGKHEDTFINGRGFNEAANLMDLNLLKDIGANSFRTSHYPYSE
                     EMMRLADRLGIVVLDEVPAVGLFQLFNAALNLTGDSEEAKNTWEVMQTKEAHELVIDE
                     LIARDKNHPSVVMWVVANEPAGHEKGARAYFEPLIQRMRDRDPSKRPVTLVNIMTATP
                     DKDEVMDLVDVVCLNRYYGWYVAHGDLKAAEKGLRQELETWQKLYPDKPILITEYGAD
                     TLPGLHSMWDIPYTEEFQVDYYDMNHCVFDSIPNLVGEQVWNFADFETTVGIIRIQGN
                     HKGLFSRNRQPKQIVREIKKRWTAIPNYHYKRK"
     gene            32616..33332
                     /locus_tag="AC1PIV_000230"
     CDS             32616..33332
                     /locus_tag="AC1PIV_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FadR/GntR family transcriptional regulator"
                     /protein_id="HIP6611286.1"
                     /translation="MAKPLVEKASERLLELILERGYEVGDKLPNEYELAQDLEVGRST
                     VREAVRSLATRNILEVRQGSGTYISSKKGVSEDPLGFSLVRDRVKLTTDLFEVRYLLE
                     PRIAERVAQFASDEDIARLEEIVLAIEEAVAAGDTKHLELDVKFHCMLAEMSGNLAMT
                     SLMPVINQSIHLINENYSNRQMKSDSLQAHRNILMAIKQRHPVAAYDSMLAHIISVRQ
                     VVLSEWFDKDMTLHGLNDHK"
     gene            33455..34075
                     /locus_tag="AC1PIV_000231"
     CDS             33455..34075
                     /locus_tag="AC1PIV_000231"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008675 -
                     2-dehydro-3-deoxy-phosphogluconate aldolase activity
                     [Evidence IEA];
                     GO_function: GO:0008700 - (R,S)-4-hydroxy-2-oxoglutarate
                     aldolase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HIP6611287.1"
                     /translation="MLKQLKENYFFAVIRGKDEEDAKEIARHAILGGIRNIEITFSTP
                     NAATVIKELQEEFSDDSSVVIGAGTVMNLKLAQAAIDAGASFLVSPHFDKEIQDLAQE
                     AEVFYFPGCATATEIVTASQAGCPIIKLFPGGVLGPGFIKDIHGPVPDVNLMPSGGVS
                     VENVADWKKAGACAVGVGSALASRVQAEGYESVTTIARSFVAALEG"
     gene            34077..35477
                     /gene="uxaC"
                     /locus_tag="AC1PIV_000232"
     CDS             34077..35477
                     /gene="uxaC"
                     /locus_tag="AC1PIV_000232"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008880 - glucuronate isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HIP6611288.1"
                     /translation="MSFNDKNFMLKNEPAKELYGKIAELPIYDFHCHLDPKEIFEDKV
                     YEDIVDLWLGGDHYKWRLMRANGISEEEITGSASKLDKFKAWARTLERAFGNPLYHWS
                     HLELRQVFGVEELLTEENAERLYHQLNAYLQEHQVSPRKLIADVRVTFIGTTDHPLDS
                     LEWHKRLAEDSTIDTVVAPTFRPDEAFIEHRNFNPFIKRLEEVTGVAVRDFASFVEAL
                     GQRVSYFAQHGCRASDISFTAISYEEATLEELDEILLARLAGKEAGQSSINKWQTAIF
                     RELCRLYKKHGFVTQVHFGALRNNHTGLFEKLGADVGVDSIGDQTCLTVNLNRFLDNL
                     VKENALPKMIWYNLNPSYNIALANTLANFQSNEEGVRSQLQFGAGWWFNDTKLGMIDQ
                     MNAYAEQGMLANFVGMLTDSRSFLSYQRHDYFRRILATYVGQWIVDEEVPEDYNRLGQ
                     FVEAISYYNAKEFFEQ"
     gene            35492..36592
                     /locus_tag="AC1PIV_000233"
     CDS             35492..36592
                     /locus_tag="AC1PIV_000233"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HIP6611289.1"
                     /translation="MKMSFRWYGKKDPVTLEEIKAIPGMQGIVTAVYDVPVGQAWPLE
                     NILELKKMVEEAGLEITVIESIPVHEDIKQGKPNRDALIENYKTSIRNVGAAGIPVVC
                     YNFMPVFDWTRSDLHHPLPDGSTSLAFLKSDLAGVDPVADDLNLPGWDSSYSKEEMKA
                     IIENYRQNISEEDLWANLEYFIKAILPTAEEAGVKMAIHPDDPPYGIFGLPRIITGQE
                     AVERFLNLYDSEHNGITMCVGSYASDPKNDVLAMTEYALKRNRINFMHTRNVTAGAWG
                     FQETAHLSQAGDIDMNAVVKLLVDYDWQGSLRPDHGRRIWGDQTKTPGYGLYDRALGA
                     TYFNGLYEANMRAAGKTPDFGIKAKTVGTKEG"
     gene            36595..37434
                     /locus_tag="AC1PIV_000234"
     CDS             36595..37434
                     /locus_tag="AC1PIV_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HIP6611290.1"
                     /translation="MTRVIEFKDKVVVITGAGGVLCGYLAKEFAKAGAKVALLDLNQA
                     AAQVFVDEIVAAGGSAKAYKSNVLSKENLEEVRQQVLADFGPVDILINGAGGNNPKAT
                     TDNEFHEVGLPADTKTFFDLDEAGINFVFNLNYLGTLLPTQVFAQDMIGRSGANIINI
                     SSMNAFTPLTKIPAYSGAKAAISNFTQWLAVHFSKVSIRCNAIAPGFLVTNQNRGLLF
                     DESGQPTARANKILTNTPMGRFGESEELVGGVFFLADENLASFVNGVVLPIDGGFSAY
                     SGV"
     gene            37434..38234
                     /locus_tag="AC1PIV_000235"
     CDS             37434..38234
                     /locus_tag="AC1PIV_000235"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HIP6611291.1"
                     /translation="MMKMEYVFCVDSDGCAMDTMTYKHKLFFGPLAAEVFGVEDKEPF
                     LAEWNRVNLYSRERGINRFVGLVKGLEFAGVTGIDNLKNWVATTDSLSNASLERLIEE
                     QPSKDLELALKWSTQVNQAIKHYSGPVLAFIGVHKGLEKLSQLGKVYVVSSANKEAVE
                     EEWTDQGLMDFVTELYCQDRGKKEDVIKLLIEEGYCPNKIMMIGDSPGDLKAAELNGV
                     HFYPILVGREMQSWADLTETIADDFAHQAFTGEKETELIQAFWNNLDD"
     gene            38281..40071
                     /locus_tag="AC1PIV_000236"
     CDS             38281..40071
                     /locus_tag="AC1PIV_000236"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 3 protein"
                     /protein_id="HIP6611292.1"
                     /translation="MTHLVDLRKKPYSLDEEAISWIEETIAQMTLDEKIGHLFVNMGS
                     QRTEDYLTGVLNDYKIAAVRYNPGPAADIWEQNYILQTKSKIPLLIAANTESGGNGAV
                     TDGTKIGDEIKIAATTDPRYAYEMGKVAGLEAAAVGCNASFAPIMDLSRNWRNPIIAN
                     RTWGANVDQVIELSKEYMRGIMEHGIVPFAKHFPGDGIDERDHHLSFASNPMTKSEWM
                     ETFGRIYGEMADAGLPGIMAGHIHLPNVEKEMHPERELDDMLPASLNKTLLDELLRGE
                     LGYNGAIVTDASHMIGMTASMPRRELLPTAIEAGCDLFLFFNDPEEDLQWMKEGLENG
                     LLSEERLHDALRRTLGLKAKLGLHLFEGRRQEIMLPKEEALALIGRDEAKQLAKEVAD
                     KAITLVKAKQEGIFPVNPERYKRILLVEVDGYKGGFGAMINAGKKRAADTLKELLEAR
                     GHQVSIWENTEARIAKLPEEERPAAIANVYASKRPIAEITDNYDLIINLVDVNSGGTT
                     QRIIWPAAKGTPDQPFYVHEIPTIIVSVQHPFALADMPQVATYINAYDGLPVTLEALV
                     AKLAGESAFTGVSPVDAYCGLVDTQIWRGK"
     gene            40082..41806
                     /locus_tag="AC1PIV_000237"
     CDS             40082..41806
                     /locus_tag="AC1PIV_000237"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001137776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 3 protein"
                     /protein_id="HIP6611293.1"
                     /translation="MPRLVDLRKKPYCLNDEQITWVENTLAHLTDEEKIGQLFVNLFF
                     FGGDAFSGNNLSNQELMNRYHIGGARYMNGSPEQVQGLINELQSYSKVPLLVAANCDS
                     GGDGAVKGGTYISSGAQSEASRDPRIPYLAGLVSAREETALGVNVNFDPCVDIVQNWR
                     NTIVNTRAYGTNADDVITYTSAYLEGLTAERDVIQCIKHFPGDGKEERDQHLVLGVNE
                     LSPEEWDKSFGRVYRHHIEAGVEMIMAGHIALPYYQQRLNPSLTDEDILPATLAPELI
                     QDLLKEKLEFNGLVITDASHMLGMTAAMRREDYVPAAIAAGCDMFLFFNNLEEDFEFM
                     LNGYRKGVITDERLHDALRRILGLKAKLNLHIKQAEGTLLKSADELAIIGCEEHLAWQ
                     REAADKAITLLKDTQKNLPISPETHRRIRLYYLEGEKEGIMAASTEVVDNLKAALEAR
                     GYEVTVNDGTTRIKGKTLQYREEVDLALTVANVIGYGAQNNYRIQWKTAMSNEVPWYV
                     HEVPTIFISLNYTTHLHDVTMVKTAINAYHHNKNTIESLLDKLEGKDAFFGVPNENVW
                     ANKWQAKL"
     gene            42262..43305
                     /gene="pheS"
                     /locus_tag="AC1PIV_000238"
     CDS             42262..43305
                     /gene="pheS"
                     /locus_tag="AC1PIV_000238"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HIP6611294.1"
                     /translation="MSNIEQQLAELSQTTLEKLKEIQHQGEKELQDLRVAVLGKKGSL
                     TDLLKGLKDLSNDMKPIVGKQVNEVRDVLTTAFEETAQKVAAAKIQQQLASETIDVTL
                     PGRQVKVGKRHVLTQTSEEIEDIFLGMGFQIVDGFEVEKDYYNFERMNLPKDHPARDM
                     QDTFYITEEILMRTHTSPVQARTMDQHDFSKGALKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGENVSMGDLKGTLEMIIKKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     DGCNVCKKTGWIEILGAGMVHPQVLEMSGIDSTKYSGFAFGLGQERIAMLRYGINDIR
                     GFYQGDVRFSEQF"
     gene            43507..44028
                     /locus_tag="AC1PIV_000239"
     CDS             43507..44028
                     /locus_tag="AC1PIV_000239"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIP6611295.1"
                     /translation="MQIDPIRLEEVSVLQELAKQTFAETFAHDNDPKELEAFFEESYS
                     LEVLTSELSDPNCQHYFLRIDHQIAGYLKLNKGSAQTEQELENAFEIQRIYLLQAYQG
                     RGLGKVLFEFALEKAEQSSCDWVWLGVWEHNYKAQKFYSKYGFEKFGQHEFAVGDKID
                     VDWLLKRPLHQKG"
     gene            44030..46429
                     /gene="pheT"
                     /locus_tag="AC1PIV_000240"
     CDS             44030..46429
                     /gene="pheT"
                     /locus_tag="AC1PIV_000240"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HIP6611296.1"
                     /translation="MLVSYKWLKELVDFDATSHDLSEKMSTTGIEVEGVEQKSAGLSK
                     LVVGQVVSAEPIPDTHLNICQVNVGEAITQIVCGAPNVKPGIKVIVALPGARIAGNYK
                     IKKGKIRGVESLGMLCSLSEIGVSDSVVPKVYADGIYHLPEDAVVGEPVFSYLDLDDE
                     IIELSITPNRADALSMRGVAHEVAAIYDSKVNFKPVVLEESDKKASDVIEVAIESDKV
                     TAYTARVIENVTIAPSPQWLQNLLMNAGIRPLNNVVDITNYILLYFGQPMHAFDFDKF
                     EGKKIVARQAKEGENLVTLDGEERDLIADDIVISVADKAVALGGVMGGASTEIDNSSK
                     TVVLEAALFDGKSIRKTSGRLNLRSESSSRFEKGINVATLTEAMDTAAAMIAELAGGQ
                     VLSGIVSAGSVDTSDVPVTATIDYVNRSLGTNLDYAQIADIFRRLGMETTGDASQFTV
                     AVPRRRWDIRIPADLVEEIARIYGYNNLPTTLPKEDGTAGELTLTQNIRRQVRSLAEG
                     AGLTEIISYALTTPDKAVEFVARPTTVTELMWPMTVDRSALRQNMVSGMLDTVAYNVA
                     RKNKNLALYEIGKIFEQSGNPKEDLPQEINKFALVLTGLVAEKDFQTPAVPVDFFHAK
                     GILEAIFDHYKLAVDFVATSEIAALHPGRTAEIHLNGAVIGFVGQVHPQTAKDYGIPE
                     TYVAEINLDAIEEALQPAQPFTDISKFPAVSRDIALLLNSDVKHQDVLDAIAGAGVKR
                     LTKVTLFDVYAGSNIEVGKKSMAYNLTFQNPEDSLTDEEVAKYMEKISKSLETLGAEI
                     R"
     gene            46484..46750
                     /locus_tag="AC1PIV_000241"
     CDS             46484..46750
                     /locus_tag="AC1PIV_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HIP6611297.1"
                     /translation="MNTQDIQEKFFREGKLIVIPKKLKSKQVLFAYLQEELAKKGSTF
                     TEKEVNAFLAEVYDDYAILRRYLVDYGYLSRDQYGLEYRIEEKR"
     gene            complement(46771..47073)
                     /locus_tag="AC1PIV_000242"
     CDS             complement(46771..47073)
                     /locus_tag="AC1PIV_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611298.1"
                     /translation="MYEFVLEYGSFPVKLIDGFVNNRSEIPDFLKEDEEMIARLNEIN
                     ELFHQLFLTIECKFDYIGKQFPDKIEQLRELYHPLADDLLAKYGNQIELKIEPFIL"
     gene            47266..48009
                     /locus_tag="AC1PIV_000243"
     CDS             47266..48009
                     /locus_tag="AC1PIV_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate polymerase domain-containing
                     protein"
                     /protein_id="HIP6611299.1"
                     /translation="MKTRIVQKQFKRKETKYIVDKKTFELLEKELRQYMMADEFATST
                     ITNIYFDNEDFDMIQDSLAKKNGREKIRMRVYDATPSESSQAFLEIKKKENKIGYKYR
                     LTSNPVSVANYIENGVIDSTIKDDKVTSELEMLRERYGTIKPKMYIYYDRVSYKGIED
                     KKVRLTIDKNLLYRDYDVDAMEGKFGKNLLDPTKVIMEVKVPEERPDWLVALLEKYQI
                     EKQSFSKYGNAYKLAHNITGEEVSKHAAV"
     gene            47996..48673
                     /locus_tag="AC1PIV_000244"
     CDS             47996..48673
                     /locus_tag="AC1PIV_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4956 domain-containing protein"
                     /protein_id="HIP6611300.1"
                     /translation="MQLFNSIFSTANSNITLAQMSMVFGVSLSMGVLLAAVYKYKSNY
                     TKEFVITLSLMPALIAVIIALVNGNLGAGVAVAGTFSLIKFRSAAGSSKEMLAVLLAM
                     AIGLATGMGFLGLAVFMTVILSACILIFENISFAQVNQNRRHLLVTVPMNFDYDQFFE
                     KQFGTSCKQADLISLKYKKKKEALILEYQVLLDKKITDKRLVDTVLSAGPLDVVLNKQ
                     MPKKKYL"
     gene            complement(48721..49203)
                     /locus_tag="AC1PIV_000245"
     CDS             complement(48721..49203)
                     /locus_tag="AC1PIV_000245"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HIP6611301.1"
                     /translation="MTKKPVQLATICYIDNGKEFLLLHRNKKENDVHQGKWIGVGGKL
                     EPGETPQACAIREIFEETGLTVTKHALKGVITFPDFTPNTDWYTYVFKITGFEGSLID
                     CNEGDLEWVPYDQVLSKPTWEGDRHFQEWLLEDKPFFSACFRYDGDKLLDYSVDFYEE
                     "
     gene            49371..49934
                     /gene="folE"
                     /locus_tag="AC1PIV_000246"
     CDS             49371..49934
                     /gene="folE"
                     /locus_tag="AC1PIV_000246"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003934 - GTP cyclohydrolase I activity
                     [Evidence IEA];
                     GO_process: GO:0046654 - tetrahydrofolate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HIP6611302.1"
                     /translation="MSKQEQIEQTIYQLLELLGEDPNREGLLDTPKRVAKMYLEMFNG
                     LEEDPKDQFTAVFSEGHEEVVLVKDIPFHSMCEHHLVPFYGIAHVAYIPSKGRVTGLS
                     KLARAVEVASRRPQLQERLTHQVAHALQDALEPEGVFVMVEAEHMCMSMRGIRKPGSK
                     TVTTVALGKYKEDAILRRELLSMIHNK"
     gene            49943..50755
                     /gene="folP"
                     /locus_tag="AC1PIV_000247"
     CDS             49943..50755
                     /gene="folP"
                     /locus_tag="AC1PIV_000247"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004156 - dihydropteroate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HIP6611303.1"
                     /translation="MSIEQLANQVTIMGILNVTPDSFSDGGHYNEVESALVQVEKLLA
                     EGATVIDVGGESTRPGATFVSEEDEIARVVPIIRAIKENYDCLVSVDTYKTGTARAAL
                     EAGADILNDVWAGLYDGDMLALAAEYKVPIILMHNQKDESYADVVGEVKNFLAERAQA
                     ALDAGVSADQIWLDPGFGFSKNVQHNLDLLQGLEQITALGYPVLFGISRKRVVDYLLG
                     GNSLPTDRDQATAALSAWAVQKGCKMVRVHNVAANRDIVKVWDQLTSGGQHG"
     gene            50748..51110
                     /gene="folB"
                     /locus_tag="AC1PIV_000248"
     CDS             50748..51110
                     /gene="folB"
                     /locus_tag="AC1PIV_000248"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004150 - dihydroneopterin aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006760 - folic acid-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HIP6611304.1"
                     /translation="MDKISLNKCRFYGYHGAFKEEQVLGQIFTVDCDLFVDLTAASQT
                     DNLEDTVHYGMVFETIKAVVEGKPYILIEKVAGVICQEIFDQFPKVEKIRLAIYKENP
                     PIAGHYDSVGIELERERP"
     gene            51107..51595
                     /gene="folK"
                     /locus_tag="AC1PIV_000249"
     CDS             51107..51595
                     /gene="folK"
                     /locus_tag="AC1PIV_000249"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003848 -
                     2-amino-4-hydroxy-6-hydroxymethyldihydropteridine
                     diphosphokinase activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HIP6611305.1"
                     /translation="MKHLAYLSIGGNMGNRQAYLQAALDKLASHPGCQLGLVSNIYET
                     PAWGKTDQADFLNLACQVYTDLSAQDFLSVFQNIEQELDRVRIEKWGQRTIDLDIIFW
                     DEEKIQEENLIVPHPYAHERAFVLKPLAEIASDYCHPILKKVVSDLLAELGEQKDIKI
                     FK"
     gene            51646..52956
                     /locus_tag="AC1PIV_000250"
     CDS             51646..52956
                     /locus_tag="AC1PIV_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HIP6611306.1"
                     /translation="MTILATLGVLLAIVAIIYWTSKNLHVIIAAPLASLIIILTNQMN
                     VLEVMLGKEQSYMAGLAGFLINNFAIFMLGSILARYMEASGATQTIANSILKVMGKDS
                     PYKGLLAITLIASILTYGGVSIFVVIFTLLPLSRPLFKELNINWALFPIPVFLGAGTY
                     TMTTLPGAPSIQNVIPTKVLGTSLTAAPIISLAASLTLLVFGLLYMAYCLKKSLANGE
                     TYTEEEDETAVVVADKTPNLFLSVLPLFSLIGTIFLMSKTPNVLAIGLLVSILLSALI
                     FYPYLPNQKEILNAATTASIVPAFATSSTVAFGTVLTLSAGFAVIQEWIQQIPGSPLI
                     SLSVSTALISGIIGSSSGAIGIASSNFLPSYLEMGINPELLHRVVVVASAILTVMPQS
                     GVMITFHNLSKLSMKRGLKYSFILVTVGHLLALFVILLLAPLLY"
BASE COUNT        15293 a         9836 c        12681 g        15169 t
ORIGIN      
        1 aaaggttgat tcacaataaa ttatttctat ctagctttgt ggcagacttg atttccaact
       61 ttggagatac gctttactat ctggctttga tgaactatgt tttactctta ccagatacca
      121 agtttgccct ggctatgatt accgcatctg aaaccttgcc gattttggca ggcctcttta
      181 tcgggatttg ggcagacaag accaaaaaca aattggatac cattcttgca actctggtgg
      241 ttcgtgtcgg tctctatgcc tttgttggct tcttgatggg atttgcacca gccctctggg
      301 ttgtggcggt ggtctgcgtc atcaacttcc tgtctgacct tgctggtcaa tacgaaaacg
      361 gtctctatat gccagtcagc ttgcgggttg tggctgctga agaccgtgaa acagctatgg
      421 cttttaagat gacggtgaaa agtcttttgc aaattgcctt ccaagctagc ggtgctatcc
      481 tgatcggatt tatgtcttac cagaatctcg ccttcttcaa tgcagggacc ttcttggtca
      541 gtcttgctat catggcaacc ctccgtccag ctcttgccaa gctactgaag gaaaatccaa
      601 tccaagaagc tgagcaaaca gaaacagaag caggtattat caagggcatg cgtaacagtc
      661 tcaaagaatc ctaccaagct gttcagaata ttccagttct caaagcgtca attgtgacca
      721 ttgccagcct gaatgccatt tttaccgcac tttcaccatt agttattcta aatatgaagg
      781 agttctcaga ctttgtgatt gtcaatgcag gaacaaccgt tgctttgatt tccattttct
      841 tctcagttgg tagtatcttg gggtcaagta tcggtatggc tttgttcaaa aatgtcagct
      901 taatcaatct cctcaaattc tctacattga tgccagtctt gattttctca ggtttctttc
      961 tccacaatat ttatgtggta ttgacgatta tttttgtgac agctatgact ttgggtgtct
     1021 tcaatccgaa aatgaatgcc ttggtcttaa atgaactgcc tgaagataaa ttggcgacag
     1081 tcggtggagg gattgatgct ttctgccaga ttggtatggt agcaggtcaa gctttagttg
     1141 ccctaatggt gacagtgctt tctgcgacaa gtatttctct catcttcctc ttgctttctg
     1201 taggactagt aagctatact attcttgtgg ggcgtaagtc taaaaatgaa gtagttgtta
     1261 aagcttagaa agtatgcgta tgaaattaga ttaccgagat tatagaagcg agattgtcga
     1321 aaaattcttt attcctttaa ttgtcaagga gcgtgaggaa ccgattgagg cggatttttc
     1381 acagaaagaa aaaggcattc tcaaagatac cttggacatt cgtgatgaga ttgaagaaaa
     1441 gttggcagat tttcgtcaag aagtcaatca agtctttgtc tggggatata tttttaacat
     1501 tttgcatagt ctttatttct atatcttgaa tgatgggcag gatccaaaga cagttgagga
     1561 agcttgtcaa ttgattttaa agctgtctca agaagaagta gaagatgcca tgcgaaccat
     1621 gttggcatct gaaaatgacg gacatcgtga gaagaccctc agcctcatgg aacttttgga
     1681 aaaaacggat aaaaagccgg cagataagtg gtactggtca ctggctatcc gcaatcccct
     1741 ggaaacagtt gagcggtctg tccatctctt ggataagatg cttccaatct accagcccta
     1801 ttttgagcaa gcaagagttg agcgggaagc ctttgctagg gattttgaca ttgagaaact
     1861 ctatcgagac tccaaacagt tgtccatgac tggcttggat gctttgagtg ttgaaaatgc
     1921 tcaattcttc gttctcagtc cgtggaatta ttggtttgct tattatggca acgaagaatt
     1981 tgactatatg aaagtcgctc ttttagcttc ctgtcgaatt gatcagatta tgctgtcaaa
     2041 tgacgagctg gatctggatg atttgacaac ggctcttaaa gtcatcagcg atagtacgcg
     2101 ctatcaggtc ttggttgagc tgaccaagcc tcatgccaag agcaaggaca ttgcagaacg
     2161 actggctatt acaggggcgg cagtgtcttt ccacactcaa aagctgatta acggtgactt
     2221 acttctcttc aatacaaaaa atagcgatgt caaatacagt gtcaatcgtg aacttctcca
     2281 agaggtcatt gccaaattga cagaggattt tgatttgtaa aaaaagcctt gtaagttaga
     2341 tcttacaagg ttcttttgtg cttataccct tcgaaaatca aaatcagacg ttgttgactt
     2401 gatttgatga gtgaaaaggt ccagtggatc ttttcagcct gttcccttga aatataataa
     2461 ggaacagtgt tctatctgca tcttacggtc acgaaccaag ttcgtctaat ttccgacctc
     2521 caacagtcta ttgccagact gttggagcta gtctgttttt gattttcatt gagtattaat
     2581 gattaaccag ctgagcagtt ggcaagtgat gatggtgata aagaaaacca gccagccttg
     2641 ctgtattata gtcagggaat gattttctag gaagaaaaag ctgatttcga ctgggataac
     2701 atggataaaa taataatagc tggcgtattc ttttagaaat tggaattttt tctggcggaa
     2761 tagatctgtg gttagggtcc aggcgactag ataggctgtg aatggaatca ggctaaatag
     2821 aaagttcttg tcgtagccct gtttgagata gatgacagtg gcttcaaaag ctaaaagggc
     2881 tgtgcagaca agtagtttgt ttttttgtcg gtattggaaa atggggtgat tgagtttgtc
     2941 ggctagataa aagcctgtca ggagaaaaat cggtgcgtag aagaggccgt tgcggctggt
     3001 gaaaaagaag gttttgtagc tgtcaaatgc ggtcaggaaa atcgattctg ccaggtagga
     3061 ggagtaggtt tcgactgagc ctagaagata gagaaggcag gctagacaag ctgtgatgcg
     3121 ccagccccat ttccttaaag aatagtggac aaggacaaga cctagcagga aggcgggcat
     3181 gtaccagagt tggtagctgg tgcctgtgta ggtcagtccg actaggagtg cgagggggta
     3241 gtggagtagg gggatttctt ggaggtttag gtagaagagg tagaagggta ggtagaggac
     3301 ggaccaggtc aggtactgct tgctgtagcg gattaggtat tgtttggaga ggctggggta
     3361 gttgcgtcgg aggaagaagc tggctgtgac catgaagtag ggaacgacca tgcgactaaa
     3421 gattgatttt tggatgaagt ggagctggtc tgtttcaaat aacctgcggc aatggagggc
     3481 gataacgaga atggctccga tgaactggat gagggagagc agtgatgtat tgagtggttt
     3541 tgtcttattt tgcatgctaa cgttcttctt ttttcttcta ttttatcgaa atctgatgaa
     3601 tatgtaaatg tttgcaaaaa gatgtggaga ggtgctggct gaaacttagt tgacaagaga
     3661 agtccagtgg aaaatatggt ataatgttag gacggagtaa atgtaaacta tctatttcgt
     3721 ttaagttaga aaggagcata tagatgaaag atttacatgc aaaattattg gctgattttg
     3781 ggattgattt ttcggatttg aatttattag aaacggcttt tacccatact tcttatgcca
     3841 atgagcatcg ccttctaaaa atttcacata atgagcgctt ggaattttta ggagacgctg
     3901 ttctccagtt gatgatttcc aaatatcttt atcaaaaata tcctgataga cccgaaggtg
     3961 agatgtccaa gttgcgttcg acctttgtac gtgaggagtc tttggctggt ttttcacgtg
     4021 cttgtggttt tgatcggttt cttcgtcttg gtaaggggga agagaagtct ggagggcgaa
     4081 atcgcgatac tattttagga gatgctttcg aggcgttctt aggagctctg ctattggaca
     4141 aaggggaaaa gaccgtggag gaatttatcc ataaggtcat gattcctcgt ttagaaaaag
     4201 ggaattttga gcgcgtgacc gactataaga ctgctttgca ggaaattttg caggtcaatg
     4261 gtgagattgc tatttcgtat caagtaatag ctgagtctgg acctgcccat gataagacct
     4321 ttgaagtgga ggtatctgct gatcagcgtg tgattggtca tggtcgtggt cgctctaaga
     4381 aattagctga acaagccgcc gccaaaaatg ctgtggaggc tagaggatag gtatgtatct
     4441 aaaatcaatt gaaatgcagg gctttaagtc ctttgcggat aagactaagg tagtctttga
     4501 tcgtggagtg actgctgttg taggaccgaa tggttctggc aagtccaata ttacagaaag
     4561 tctacgttgg gccttgggag agtcgtctgc taaaagccta cgtggaggca agatgccaga
     4621 cgtcatcttt tcgggaacag aaagtcgcaa ggctcttaac tatgcctcgg ttgtcgtgac
     4681 cttggataat agcacaggtt ttatcgccaa taaacagaaa gaaatcaagg tagaacgcca
     4741 catttatcga tctggtgata gtgagtactt gattgatggg caaaaggttc gtctacggga
     4801 tattcatgat cttttcatgg atacgggctt gggacgtgat tctttctcta tcatttcaca
     4861 agggcgggtt gaagcaattt tcaattccaa gcctgaggaa cgccgtgcta tttttgaaga
     4921 ggcggcaggg gtcttaaaat acaagacgcg taaaaaagaa acagaaagta agttggcaca
     4981 ggcccaggac aacttggacc gcttggacga tattatctac gaattagata atcaggtcaa
     5041 accattagag aaacaggcac aaactgctaa gaaatttcta gaattagatg gtcaacgtaa
     5101 ggaattatac ttaaatgttt tggtggctca gttgtcgctt ggtaaggaaa agttatcgga
     5161 aaaagaggcc gaactagagt ctgtcaaaac tgaattgact agctactaca aacagcgttc
     5221 tgagctggag caagaaaatc tgaacttgaa agagaagcgc caccgccttt cagaacaatt
     5281 ggagcgtgaa caggcagttc tgttggattt gaccaagtta atcagtgatt tggagcgaaa
     5341 aattgaggtc cataaactgg aatctagtca aaacgaatca agtcatcaag aagcgcaggc
     5401 gcgcttggaa aacttgttga ctagacgaga gcagttggca gaacagattg agcaaaagca
     5461 agaaacgctt gcgcaattag atagttcctt gtctagcttg aaagacgata ttgctgcggt
     5521 agacaaagaa atttcctact tttcagaaga tcctgatcag gttttagatc atctgcgtga
     5581 acagtatgtt gctctgatgc aggaagaggc agaagcttca aacagtctga ccaagattca
     5641 gcaggatatt gccaatcaaa tcagtctttc agagagtaaa tctgaagact tggcacgctt
     5701 gcagacggaa aaacaaacag ctcaagaagt acttgataag agtcggaaaa gtttagaaga
     5761 agctgatcac gtgttacgcc agttgcttga gagctatcag accaaaaaaa cagaattgga
     5821 tcaagtccag actgcttatc aggctgagca aggtcgcttg tttgatttgc tggatcagtt
     5881 gaaaggcaag caggctcgtc agtctagttt agaagctatt ttaaaaaatc actccaattt
     5941 ctacgcgggg gttaaggctg tcttacaggc ggcaccaagc ttaggaggaa ttattggagc
     6001 agtcagtgaa caattgacct ttgatactcg ttaccaaacg gctttggaaa ttgctcttgg
     6061 cggtgctagt caaaacgtca tcgttgaaga tgaagcgact gctaaacgag ctatcgcatt
     6121 tttgaaagaa aaacggcaag gacgggcaac cttcttacct ctaacaacta tcaagccacg
     6181 tcagctttct ggacagcaag tctctttact agaatcttca gaaggattct tggggcttgc
     6241 aagtgatttg gtgacttatc agccaaattt agatgcgatt ttccaaaatt tgctaggcac
     6301 tattgcgatt tttgatagca ttgaccatgc caaccaggcg gcgcgtgcga ccaagtttca
     6361 agtgcgtatg gtgaccatgg atggagcgga aatccgtcct ggtggagcct ttgctggtgg
     6421 tagcaatcga aataacagca cgacctttat caaaccagaa ctggatgctc ttttaggaga
     6481 aatagcagag ctgtctagcc agttgcagga gcaagaaagc ttggttgcag ctaagaaaac
     6541 tagcttagac caaaccagag aagccttgga aacgattaag gcggaggggg aagaagctag
     6601 attgaaccag cagagcgcaa ggattcatca ggaacaggca gaaaatagac tggctcagct
     6661 atcagcccag tatgacctgc aaatgagtca ggttagtccg accattttga ctgagctaga
     6721 agaggctgct gctaaggaag aagtaaatgt ccaagccttg aatgagaaaa aactagcctt
     6781 ggatcaacaa atcaatcaag tccgtgataa tcgcgacagt attcaagaaa gcttgcagaa
     6841 actacagact cagaagggtc aactaacttt ggaacaagct gaactgacta gccaacttcg
     6901 ttttgaacag acagatctga gacgtttgca agaagaaaaa gtggttgcag ataaggaaat
     6961 ttctctttta gaggatatga ttgaccagaa gttagaagct cttgaagata ctagcattga
     7021 gattcttgaa gaacaattgc aggccgcatc tgataagcaa aaccagacca atcagattct
     7081 aattcgctta aagtttgagt tggaagatat tgatgggcag tttgaagact tggaagaaag
     7141 attgcaacaa gctcggacta agaatgatga tttgatccgt aagcaggcta agttagaggc
     7201 ggattgtgag caagcgggcg ataaattacg gactttactt ggtaatttga ccgagcattt
     7261 caaattgagt tttgaagctg ctcagtctca ggccaaggaa gttgagaatc ttgcagttgc
     7321 tgaacaaagc ctcaaagacc tagaaagagc tattcgtgct ttgggtccag tcaatttgga
     7381 tgctattgag cagtatgacg aggtcaataa ccgtctgacc ttcctcaatg agcaacggac
     7441 agatattttg tcggcgcgtg atttactact agatactatc cacgagatgg atgatgaagt
     7501 caaagagcgc ttcaaggtta cttttgaagc tattcgtgaa agctttaagc agacattcaa
     7561 acaaatgttt ggcggtggtt cagcggattt gattttgaca gaaggtgacc tattgactgc
     7621 gggtgtggag atttctgttc aacctccggg taagaaaatt caatctctca atcttatgtc
     7681 aggtggcgaa aaagcccttt cggccctcgc tctgctattt tccattatcc gtgttaagac
     7741 cattcctttt gtaattctcg atgaggtgga ggcagccttg gatgaggcga atgtcaaacg
     7801 ttttggcgac tacctcaacc gttttgataa ggagagtcag tttatcgtcg tgacccaccg
     7861 taaagggacc atggcggcag cggatgccat gtatggggtg accatgcagg aatctggcgt
     7921 gtccaagatt gtttccgtta agctgaaaga tgtggagaaa ttatgattaa caaaatttac
     7981 gccagtgata tggatggtac ctttttacga gaagaccata gttttgataa ggaacggttt
     8041 cgtcgtatac tgaatcagtt caaagaaaaa ggttatttat ttgtggcagc aagtgggcga
     8101 tctatgcaaa gcctgaaact tgtttttgaa gattttgtag atgaaatcgg gtttgtagct
     8161 gaaaatggtt caatcgttga atatcagggg cagactatct ttatggatga tccaattagt
     8221 cctgaaattt atctgccgat tatcgcaggt attgatgcag gtccctttgg tagcagtcgt
     8281 tccatggtgc tgtctggcct cgaaaacttt tatttattaa aaaatgctga gcctcagttt
     8341 ttagaagcga tgacgaatta ttacgcacat tttcgattgg tagacacatt tgaagaagtt
     8401 cgagaagaga ttataaaaat caatgccaaa ttttctcctg aggaaatgga cgatgctaga
     8461 cgatggttaa atgatacatt tgaaggtgta acggccatga caactggttt tgacaatatt
     8521 gatataattc caaatggttc aaataaatca gttggattga gtcatctctg tgctcatttt
     8581 ggaattaccc gtcaggatgt agtggcattt ggtgataatc aaaatgattt ggatatgttt
     8641 gactttgctg gtctggctct tgcgacagaa aatgcaagag aggaagtgaa ggcccaggca
     8701 gattggatga ttggtcattg caatgatgga gcagtattag cctatttaga ggaggaagta
     8761 aatggcaatt aagttgattg cattggattt agatggaaca cttctgacat cggacaaacg
     8821 gatttcagaa gctaataaaa aggccttgca ggcagcgcgt gagcgtggag tttatgtagt
     8881 tctgacaaca gggcgtcctt tacaagctat cggtactttt ctagaagaac tagatctgtt
     8941 aggggagaat caatattcga ttacatttaa cggtggtcta gtccaggaaa atacaggtcg
     9001 agttttggat aaggttggct tcaccattga agatgtgcgc accatccgtc gtgtgacaaa
     9061 tgacttggac cttcctctgg atgttctcta tggtggcgat gtctattctc taccatcagc
     9121 ccatgaatca ctttatctaa cttgtaatcc attgcttaat aaaattgtgg caagcgatga
     9181 ggaaatgcca gaagattttg tctacaataa ggcagtttca gctgtggcag cagacttttt
     9241 ggatggacaa attccaaaaa ttcctgcgga acttcacgag cgtttcgaga ttttcaaatc
     9301 gcgtgatatt ctgctcgaat ggagtccaaa aggtgttcat aaagcaaatg gtttggctaa
     9361 gttgattgga catctgggga ttgatcagtc agaagttatg gcctgtggcg atgaaggaaa
     9421 tgatctttcg atgattgaat gggctggtct gggtgttgcc atggctaatg cgactgatga
     9481 aatcaagtct gcggccaacc ttgtcctgcc aaaaaacaat gatgaagatg gcattgcttg
     9541 ggtcatcgag cactatgtat tgaatgagga ctagtatggg attatttgat cgattatttg
     9601 gacaaaaaaa acaagaggag caagtcgctc ttgttgaaga agtggaaagg gagcagtcgg
     9661 cttctagcga agatacagta actactgaag ttgagtcagc tactcaagaa atggaaaagt
     9721 tccagtctga agtagcagag actgaattga cagccgaaca agaagctcag aaacaacgga
     9781 ccttagacat gatggctcaa tattatgcag ccaaagaagc cgctgcggct cgagtgaagg
     9841 aagcgcagga acaaggcttt gaccctgcta ttcaaaccaa ggtcaaggaa gagcctgttg
     9901 aggaagttgc tccagtaggg caagaaagtg aacaggacaa gtaccagcgt accttgaaaa
     9961 agacgcgtac aggatttggg gcaaggctca atgaattctt tgccaatttc cgttcggttg
    10021 atgaagaatt tttcgaagag ttggaagaaa tgctgatttt gtcagacgta ggtgtgcaag
    10081 ttgcttctac gctgacagag gagctccgct atgaagccaa gctacaaaat gccaagaaga
    10141 tagatgaact ccgtcgtgtt atcatcgaaa aattggtgga tatttacgaa aaagacggtc
    10201 aattcagtga gcaaatcaat ttccaagatg atttgacagt catgctcttt gtcggtgtca
    10261 acggtgttgg gaagacgacg tctatcggta agttagccta caagtacaag caagctggca
    10321 agaaggtcat gttggtcgca gcggacacct tccgtgcggg tgcggtagcc cagctggtcg
    10381 agtggggtcg ccgtgtcgat gtgccagtag tcacaggacc tgaaaagtca gacccagcta
    10441 gtgtggtttt tgatggggta aaacgtgccg tggcagaagg cgtggatatt ctcatgattg
    10501 atacagcagg tcgcttgcaa aataaagaaa acctcatggc agagctggaa aaaatcggtc
    10561 gcatcatcaa acggacccta cctgatgcac cgcatgaaac cctcttagca ctggatgcct
    10621 ccacaggtca aaacgccctc agtcaagcca aggaatttgc aaaaattact ccattgactg
    10681 ggctagtctt gaccaagcta gacggtacag ccaagggtgg tgtcgttctt gccatccgtc
    10741 aggaactgga tataccagtt aagctaattg gtttcggtga gaaaatcgat gacatcggtg
    10801 aattcaaatc cgaagaattc atgcgtgggc tattggaagg attggtatag aaaaaagtcg
    10861 ttagttcaat gaactagcga ctttttctat ctgtatgcag cagtgagtaa atggcaatat
    10921 ccacaatacc ccgattgttt cgagcggctt ggcggagagt tccttcatag gtcataccga
    10981 ctttttccat gacacgacca gaaggacgat tttcactatc gtgaacagct gtaatccgta
    11041 aacagcccac ttcctccaat aaatagtgat taacagcttc aagagcttcg gccatataac
    11101 tttgccccca ccatttactg cccaacaccc aacctaattc ggcagcttga actctttcat
    11161 caaggctgac aacggaaata tctccaatgg gttgctgatt ttctttgagc tcaattaccc
    11221 acctgtatgt tttttcctgt gaataggatt gaagacagaa ctggacatag tcttcagtat
    11281 cttggagtgt ctgatgcgtt ggccaggtca gataggtggt aaccttttca tctgaagtcc
    11341 agttttggaa aactgattca acatcgcttg cttgaaaagg gcgtaaaatt agacgttctg
    11401 tttctaaaat ctgagttcct ttatgttgca tcttatttcc tcctcaacaa cgcttctatc
    11461 cagtctggtg cataggcaga agtgcagcct tttggaactt tcatgttcgc atagacggcc
    11521 aattcctgac caattgcaag accttgttcc aggtagtcag gataggtaac tgcaatctcc
    11581 actaagcatt ggttcatggt ccattggaca agcgggtcag cggtttgcaa atgctggcga
    11641 atatggtcta gagattcttc gatttcttga tttgaggcag ttcttccagc aaagtatttg
    11701 gcacgaagga accaacctaa tcgttgaaaa atagcctggt cttggatgag taagtattct
    11761 tcccagtctt tgctatcctt gcgtttgctg aggataatgg aagccaattt atcgaggaca
    11821 ttgaccgaaa tttgttcatt gaggcaattc tctaggtcag cttggggaag ttggttaggt
    11881 ttagccttgg caacttgaat agctaaatat tgtgcttcta ggacacctgt ttgccagagt
    11941 ggggcaaata agtccagtcg atttttatag gccttggcga taccagaaat agctcccatt
    12001 ggaactccgt agtagggctt agtttcgcca attttttcat aacgcttgag ggtgccagca
    12061 tggctggcta cttcaagttg ggtgagaatg atgttcattt cagtcataaa tatctcccaa
    12121 aaaaactgga ttgctccagt ttttatatgt agtcgtttag tttgctttta gtacaaggca
    12181 acgaggtgca ggttgctaga acagcctaga ggctgttcta ggttggaaat aagacatgcg
    12241 aagcaagtca ctttcgtgga gtacggcaaa gcgagttaac gaagtaatca aagctaaact
    12301 aaatgactat ttcaataaac cacgttcacg ataccagaca tcaggtgtcc aaacccactt
    12361 gcaactgtag ctttctagca aatcaaaggc tgcctcaggt cccatagttc cagctggata
    12421 ggtgtggagt gggacttggt tgcttgccca caaatcaaca atgcggtcaa tcaagctcca
    12481 gcttgctttc acttcttccc aatggctaaa gttagtagaa tcaccattta ggacatcgaa
    12541 aaagagtttt tcgtaggctt cgggtgaatt tccaagagca gttgcattgt ggcggaagtt
    12601 gagtttggca ggagtaagag caaaatggga accaacttcc ttaccgttga tagagagcat
    12661 gaagccttca gttggttgga tgaagatggt caatacattg gcttcggaag gttgaccaaa
    12721 aatatcttcc gcatgcttga aggtgatggt cacgcgcgtg cccttttctg tcagacgttt
    12781 acctgtacgg aagaagaaag gtacatcacg gaaacggtca gtatcaacga agaagacacc
    12841 tcctgcaaag gtttctgtct gagaaccttc ggcaatattt ggttcatcca agtagctaac
    12901 gtagtctttt ccgtcaatgg aacctgctgc atattgacca cggatgaagt tgcgtttgag
    12961 gtcctcatca gaaggctgac gaaggtgttg gaagacctta atcttttcag cgcggacatc
    13021 ttcctccttg aagctggctg gcttatccat tgctagaagg gaaagaactt gaagggcatg
    13081 gttttgcacc atgtctttta aggcgccaga atgatcgtag tagcctccac gatcctcaac
    13141 accaatcgct tcagcaaatg taatttggac gttatcgatg taatcgcggt tccaaatatg
    13201 ctcaaaaatg atattggcaa agcgaaccgc aaagatattt tgcaccattt ccttgcctag
    13261 gtaatggtcg atacggtaga tttggtcttc attgaaggct gctgccaatt catcattgag
    13321 tttggtagct gtagcaaggc tagttccgaa aggtttttca attatcaagc gttcaaaacc
    13381 ttgtccatca acgatttgct cagatttgag gtgtttggca atggttccga aaaattcagg
    13441 tgccatagag aggaagaaga ccttgttgtg ctgggtattg tatttttcac acaagtcgtc
    13501 ctgcaattta cgaagagcta cataatgttc cgtgtcattg acatcgtggc tttggtagta
    13561 gaaatgattt gcaaattcat gagcttgacg tggtgtgtca ggcagatcac ctagtgattc
    13621 aatgacggtt tgctcaaaaa attccttggt ccagggtctg cgagctgtac caattactgc
    13681 aaaattttct cggatatggc ctgccttata aagacggaag agggatggat agagtttgcg
    13741 tttggcaagg tcgccactag caccaaaaat tgtaaacaat acatgtgatg acataatttc
    13801 attcctatct gttgaatatc attaatagta taccacaaat tgtcagaaaa ttcacttttt
    13861 tagttggaat tattagaaaa cacggtagac atacggagaa tctggctgct caatctgaac
    13921 catcgattgt aattcaagtg ttgggagatt ttgtttcaac gatgtgtggt aggaaacctt
    13981 gattgttcct ctggctttta cccaagtatt gttaggaaat tctgtggtag cccccgtaga
    14041 gagtaagcca tataccccag aatcagcaat gcagtgaata ataccaaagc ggaaaaggaa
    14101 aaattgctgg ctattgtcag ggtcattgta gacaaatcca atcatttcaa tcgtttttcc
    14161 tgaaaattcc gtaggatagt cgtagattgc ttccatcact tccatatagt tttcattagt
    14221 aacgacaatg gtttcttcag ccaagtatct atcagcaatt tcacgcatct ggttttgata
    14281 ggcagatttt gtaaaataaa tagaagtatc aggcttgaga tactgaacag tcgccccttc
    14341 ttggttttgt gtattagtat cgttttctgt tgctagtggg aaatgatagc ccttggcagc
    14401 aacagttgtt gaatccaggc ttaccgtagg aaagagccag gctatagcaa gaggaatgag
    14461 caatagtcca atgcttgata gtttggcaat tttgcttttt aaatggctat gtactcgaat
    14521 ttcttttacc cagacataca attgtacgat ggcaagtatg aaagataaaa ccatggatag
    14581 ataggctaga tagctatagt gcagattaat gtattggtct aattttccag agatataaag
    14641 atacatggtc atttcaaagt aacctgcaag aattaaaaaa cgaatcatac tacacctcca
    14701 agtatcagac tatatcccaa aataacgaga gtgatagtaa tgataaaacc gactataaat
    14761 ttccctttga aataatgttt catcatgagc aagtttttaa catccaccat gggtccgata
    14821 actaagaaag ccattactgg ggcgaatccg aagctggata gtagtgatgc accaataaag
    14881 gcatcggctt cggaacatag ggaaagaaga aaggccagca acatcatcag taaaatagct
    14941 gttaatggac tgtgaccgat ggtagtcagg acagcggttg gaatatagac ttgtacgaga
    15001 ctggcaaata gacaaccaaa gactaggtaa cgtcccgtat caaaaaattc atcaatggca
    15061 tgaataagtg cgaagccaac tttttgccag ctggttttat ctgaataatc atgctggtga
    15121 tggtcaaact tgcttccttt aagaattggt ccttttacga aaaaaccaag aatgattccc
    15181 aatactaggg atacaatgat ggctcctagg gctctataga gtgcgaaaag tagggaattt
    15241 ccaaaagcgg taaaggttgc aaaaaggacg ataggattaa tcacaggcgc cgttactaaa
    15301 aagggaacag cagtataact cggcactttt ttctctaata gccgattgac aatagggaca
    15361 ataccacatt cgcaagacgg aaaaatgaag ccgataaagg ttccaaatag aatggcaaga
    15421 aacttgtttt taggtaagag tttacgaacc ttatctggtg ttataaacac atcgataaaa
    15481 cctgaaataa tagctccaat caagacaaag ggcaaggctt caatcatgat agataggaaa
    15541 atagcccccg cctgtaggac ggaggtaggt aattgatcaa gaccaagcat attatttttt
    15601 atcctgattc aagttgtttt tctcggaatg ttcttttgat tttggatctg gatactcaat
    15661 ttcttccaat ttttcaaatg aagcaaattc ttccagcatc ttttctaaat catcttgtcg
    15721 tttataagtt acagccatag ggcacctcca aaaattttat ataaacatta tacatttttt
    15781 actaaaaatt atctaaagga atctgttttt attgaagcgc aaatatagtt cgcaccctca
    15841 aatcatgata taatattctt atgaaaacaa gaatatcaga attagttagc gtgctcaatc
    15901 aatacgctaa agagtattat caattggacc aacctagcgt atcagatgca gaatatgata
    15961 cgctttatcg tgaattagta gagctagaaa cggctcatcc agaactgatt ttaccagata
    16021 gtcctaccca tcgggtcggg ggaaagatgc tagacggatt tgaaaaatat agtcatgttt
    16081 atcctctttt tagtttgcag gatgcctttt ctcgtgaaga gttagaagct tttgaccagc
    16141 gagttcgcaa ggaatttcct caagcaacgt atatctgtga attgaagatt gatggtctgt
    16201 ctatttccct gacctatgaa gcgggtaatt tagtcgtggg tgctacacgt ggtgacggta
    16261 gtgtcggtga aaatatcaca gaaaatctca aacgagtggc tgatgttcct ttgaccttac
    16321 ccgaagctgt ggacatcact gtccgaggtg agtgttatat gccaaaagct tcctttgacc
    16381 gtgttaacaa acagcgtcag gaggctggtg aagctgaatt tgttaatccg cgtaatgcag
    16441 cagcagggac cctccgccag cttgatacgg gagtggtggc ccagcgtggt ctcgctactt
    16501 tcctctacca agaggctagt ccatctgaag cgactagtca gtcacaagta ctggagaaac
    16561 tggatgctct gggatttgtg accaaccacg aatattgctt ggcggagtcg attgatgaca
    16621 cgtgggattt tattgaaaaa atagcagagc gtagagatga tttaccctat gagatagatg
    16681 gtgttgtcat caaggtaaat gatttagcta tacaagaaga actaggattt acagttaaag
    16741 cgccacgatg ggcagtagct tacaagtttc cagctgagga aaaagaagca gaaatcttgt
    16801 cggttgattg gactgttggc cgaacaggtg ttgtgacacc aacggccaat cttagtcctg
    16861 ttcaactggc aggaacgact gtcagtcgag caactttgca taacgtagat tatatcgccg
    16921 aaaaagatat tcgtattggc gatacggtca ttgtttataa ggcgggagat attattccag
    16981 cagttctgaa agtggtggac aagtatcgaa aagagcaaga aatcatgccc attcctagtc
    17041 attgtccgtc ttgtcagagc gacctacaac actatgagga cgaagttgcc ctccgctgta
    17101 tcaaccctat ttgtcctagc cagctgatga gtaagttgga acattttgca agtcgggatg
    17161 ctatgaatat cgcagggcta gggtcttcaa tcgttgaaaa actctttgga gcaggcttgg
    17221 tacacgatgt tgctgatatt tataaattaa ctgttgatga cctattgacc ttggaaggtt
    17281 tcaaagaaaa atcagctaac aagctctatc aagccattca aacttctaag agtaactcag
    17341 cagaatgcct cctatttgga ctaggtattc gccatgtagg tagtaaggca agtaagattt
    17401 tagtagaaaa atttggtgat ttagaaactc tagcatttgc tgatcaagaa gcaattgctt
    17461 cgctagaagg tcttggtcag gttattgcta agtctttgac aacttttttt gctagtgagg
    17521 gtgcgcaaca acttttagcc gaacttaagg aagctaaggt aaacttaacc tatctcggcc
    17581 aagtagtaga tgaaaatgct gcgctatcgg gtatgacagt tgtactgact ggtaaattgg
    17641 agcgaatgaa acgaaacgaa gccaaagcca aattagaagc tttaggggca aatgtagcgg
    17701 gatctgtttc taaaaaaact aatcttgtgg ttgccggaac agatgcaggc agtaaattga
    17761 ccaaagcaca ggagctaggt attgaaataa aagatgaggc ttggttagag agcttgtaaa
    17821 ggtaaaacga tggaagaaag aaaacgtgct agactaatat ataatccgac ctcaggtcaa
    17881 gaaatcatga agaaaaatgt ggccgaagta ttggaaattt tggaaggcta cggttatgag
    17941 acttcagctt tccaaacaac tgctgagaaa gactctgcaa agaatgaagc tacacgtgcg
    18001 gcgcttgcag gctttgactt gattatcgcg gctggtggag atggaacaat caatgaagtc
    18061 gtcaatggaa ttgctccact tgaaaaacgt ccgcagatgg ccatcatacc gactggcacc
    18121 accaatgact atgcgcgtgc tttaaaagtg cctaggggaa atcctgtaga agcagctaag
    18181 gttattggta agcagcagac aattttaatg gatattggtt tagccaaaaa tcaaaaaaat
    18241 ggttttcatc aagaacatta ttttatcaac attgctgcgg caggtacact tacggagttg
    18301 acctacagtg ttcccagtca acttaagacc atgtttggct atttggccta tgtagtaaaa
    18361 ggagcagaac tcctgccaca agtacaattt acacctgttc gtgtagagca tgatgagggc
    18421 gtgtttgaag gctcggtttc aatgattttt gttgccttaa ccaattcaat tggaggtttt
    18481 gaacagatcg ttcccgatgc taagttagat gatggtaatt ttaccttatt gatggttaaa
    18541 acagggaatc tatttgaaat tctacatctg attcgtcaag tcttagatgg tggcaaacac
    18601 attgagagtg atttagttga atacataaaa accaagagcc tatccatcga aaatctgaac
    18661 ccagataacc gtctactgct caatctagat ggagagtttg gtggggaagc ccctgtacgt
    18721 ctgtacaacc tatcaaacca tatagagttt ttcgcagata cagatctggt ttctgaccat
    18781 gcaatcactc ttgatactga tcagatgaat cgagaagata tggccaaacg attcattgaa
    18841 gaaacagacc atattgatga agctattaaa taggaagaaa agatgaaata ctcttttctt
    18901 tttattttac aaaaacgaat taaacgctta caatggcggt attttcttga caaatagatg
    18961 ttttaggagt atccttacat ggtattaaat tttaaaagga gaattcgtta tgagtttagg
    19021 cgcattggcc cttggattgg cctgtcttgg tgtaagtatc ggtgagggac tgttggtggc
    19081 ttcatacctt agttcgactg cacgtcaacc agaaatgcaa agtaaattga tggctggtgt
    19141 atttttgggt gttgccttta tcgagggaac tttcttcgta accttggcta tgacatttgt
    19201 cttaaaatag tagaaaatag agaaatagaa aaggggggaa cctccattgg aagaacattt
    19261 aagtccaacc cttacccttg gtcccgtaac ctttgacctg accatggtat tggtttctgt
    19321 cattaccatt tccattattt tcttacgagt tttttgggct agtcgtcgga tggagctcaa
    19381 gccaaaagga aaacagaatg ttttggagta tgtttacgaa ttgaccatca attttacaaa
    19441 agggaatctt ggcgatgcgg aagcaaagcg gtattccttg ttcttcttta cagtctttac
    19501 ttttcttttg gttgccaata atctaggttt gatgaccaaa ttggaaacag cagaaggaca
    19561 taatttgtgg acttctccaa cagccaatat ggcttacgat ttcggtttgg caacaattgc
    19621 aacagtattt tgtcatgttg agggtattcg tcgtcgcggt ttcaaggcat acctcaaatc
    19681 ttttgtgaca ccctgggcta tggctccaat gaacattttg gaagaagtga ccaaccttgt
    19741 gtcgcttgct cttcgtctgt acggtaacat ttatgctggt gaagtgcttg tctctcttct
    19801 tctacaatta tctcaacaaa gtgcacttgc atatccaatt gcctttgctc tgaacgttgt
    19861 ttggacagca ttttctgtat tcatttcatg cttgcaggga tatgtattta tcatgttggt
    19921 atctatgtac ttaaataaaa aaatcagtag tgagagtgaa taggaaaggg aaagacaact
    19981 atggcaacaa ctattacaat gcaatctagt accattcttg gaaactttat cttggtaaca
    20041 gcctcatttg cagtacttat tattcttatt cgtgtttttg catgggataa aattacaggt
    20101 atttttgaag aacgtgccaa taagattgcg aacgatattg atgctgcaga agaaaaatta
    20161 acagcagcag caaaccttgt tcaacaacgt gaagatgagt tggtacaggg acgtattgaa
    20221 agtcaaaaga ttattcaaga cgcggttgaa cgcgcaaaac tagagaaaaa acgtattctt
    20281 gagcaagcag atgttgaaat tcaaggattg aagcaaaaag ctcaattgga aattgaagct
    20341 gaaaaacgtg aagcacaaga aaacttgcgt gttcaagttg ctgaattggc agttgatctt
    20401 gcaagcaaaa ttattttgga agatttggac caacaagctc atagtaactt gattgaccgt
    20461 tatttggaca aactaggaga caagtagatg aacgctagag aaaatgccat cgtgcaaaaa
    20521 tatgctctat catttgttga aaaagtcagt gatcatgcag atatttggga tatgtatgac
    20581 cagatttctg acttgatttc catcattcat gatagtaagc tgaatcgaat cttgctgtca
    20641 gcgacagtat cgagagaaga aaaggctgac tttgtaagga cggtacgtca atctagtttc
    20701 tggcaaatca atgacttgat tgaagatgtt attcgtgatg gtcatgcaga cttgcttctt
    20761 gaaacccttg agcgtgtcca attacaaatc agtaaattta aaaatgaatt tgaagcccgt
    20821 gtggtttcag tctatccgtt gacagaagct caaaaagagc gtctccgtca cttggtagaa
    20881 caacgatttt ccttgcgtgt acgcaatatc acggaagaac ttgatcaaag tctcctcggt
    20941 ggttttattg taacggttaa ccataaggta atcgatgcaa gcgttcggac acagttgaag
    21001 gacattagaa aaaaacttta aaaaatagaa agtggtgttc ttttgattaa tgcacaagaa
    21061 attagcgctt tactaaaaca acaaattgaa ggctttcagc ctgactttga ctacacagag
    21121 actggtgtcg taacctatat cggtgacggt atcgcccgtg cgcaaggtct tgacaatgcc
    21181 atgagtggag agcttttggt atttgaaaat ggcaccattg gtatggcaca aaacttagaa
    21241 accaacgatg ttggtattat cattctcgga caatttaccg atattcgtga agggtcagtt
    21301 gttcgtcgta ctggtaaaat tatggaagta ccagttggtt cggctttgat tggtcgtgtc
    21361 atcaacccac ttggtcaacc tgtggatggt cttggtgaga ttcgtactag taagactcgt
    21421 ccgattgaat atccagcacc aggtgttatg caacgtaagt cggttaatga accgcttcaa
    21481 actggtctca aggcgattga cgctttggtt ccgattggtc gtggtcagcg tgaattgatt
    21541 attggtgacc gtcagacagg gaagacatct gtagctattg atgctattct caaccaaaaa
    21601 ggccaagaca tgatttgtat ctatgtggct atcggtcaga aagagtcaac tgttcgtact
    21661 caggttgaaa cccttcgtca atatggtgct ttggattaca caatcgtagt aactgcatct
    21721 gcttcacaac cgtctccatt gcttttcttg gctccttatg ctggtgttgc gatggcagaa
    21781 gagttcatgt atgaaggcaa acacgtcttg attgtttacg atgatttgtc gaaacaagcg
    21841 gtagcttacc gtgaattatc tctcttgctt cgtcgtcctc cgggtcgtga agcctatcca
    21901 ggggatgtat tctacttgca cagtcgtttg cttgagcgtt cagcaaaggt ttcagatgaa
    21961 ttgggcggtg gctccattac agctctacca tttatcgaaa cacaggcggg agatatttca
    22021 gcttacatcg cgaccaacgt gatttctatc acggacggac aaatcttctt gaaggacgat
    22081 ttattcaact ctggtatccg tccagccatt gatgcgggtt cttctgtatc acgtgtaggt
    22141 ggctctgcac agattaaggc catgaaaaag gttgcaggta cccttcgtat cgacttagct
    22201 tcttatcgtg aattagaagc ctttactcaa tttggttcgg atttggatgc agcaactcag
    22261 gctaaactca accgtggtcg tcggactgtg gaagtgttga aacaaccatt gcataagccg
    22321 cttccagttg aaaaacaggt tttgattttg tatgctttga caaatggctt cttggattca
    22381 gtgccaatcg atgatatttt ggcatttgaa gaagaactgt acgcatattt tgatttgcac
    22441 tacgatggtc ttttggatgt tattcgtaca acaaaagatc ttcctgatac agatgaattg
    22501 aatgctgcta tccaagcttt caaagaccag tctgtcttta agtaaaggag tgaataatgg
    22561 caggttctct caatgaaatc aaatcaaaaa ttgcatcaac taagaaaacc agtcaaatca
    22621 ccggtgccat gcagatggtt tcggcttcta aattagccaa atcagagcaa ttagcgcaat
    22681 cctttcaaat ctacgctagc aaggttcgtc agattacaac ggacctcttg cgtggagagt
    22741 tgatggcttc agatacaagc aatccaatgc tgattcgtcg tccagttcaa aaatctggtt
    22801 atattgtcat tacctctgac agtggactaa aaggttctta taattccagt attttgaagg
    22861 ctgtgatggg gatgattgaa caggatcatg actcaaaaga cgagtatgag attattgcca
    22921 ttggtagtat gggagctgat ttcttccgtg cccgtggtat caatcctgtc tttgaattgc
    22981 gaggtttagc agacaaccca agttttgaag aggttcaaaa aatcatttct aagtctgttg
    23041 aaatgtacaa gaatgaactc tttgatgagt tgtatgtttg ttataaccac catgtcaata
    23101 gtttgaccag tcaggtgcgt gtacaacaga tgcttcctgt agaagatttg gaccacaatg
    23161 aagcagatgg ttatacagct acctttgagt tggaaccaaa ccgtgaggtt attttggaac
    23221 aactcttgac tcaatatgca gaatcaacta tttatggagc gattttggat gccaaaactg
    23281 ctgaaaatgc agcaggtatg acagccatgc agacagcaac ggataatgct aagaatgtca
    23341 ttaacgattt gacaatccaa tacaataggg ctcgtcaggc agcgattact caggaaatta
    23401 ctgagattgt agctggtgcc tcagcccttg agtaatagaa atagaggaaa tagaatgagt
    23461 tcaggcaaaa ttactcaggt tgtcggacca gttgtagacg ttgcgtttgc agcagaagat
    23521 aaacttcctg agattaacaa cgcactcgtt gtatataaaa atgatgattc caaacaaaaa
    23581 gtcgtgcttg aagtggcttt ggaacttggt gatggcgttg tacggaccat tgccatggaa
    23641 tcaacggatg gattgacacg tgggatggaa gttctcgata caggtcgtcc catctctgtt
    23701 ccagtcggta aagaaacgct gggtcgtgtc ttcaatgtgt tgggagatac cattgacctt
    23761 gaagagtctt ttccggcaga ttttgaacgt gagcctatcc ataagaaagc gccggctttt
    23821 gacgaattat ctacttcaag cgaaattttg gaaacaggga ttaaggttat cgacctccta
    23881 gcaccttatc taaaaggtgg taaggttggt ctcttcggtg gtgctggtgt tggtaaaacc
    23941 gttcttatcc aagaattgat tcacaatatt gcccaagaac acggtggtat ctctgtattt
    24001 accggagttg gcgagcgtac ccgtgaaggg aacgatcttt actgggaaat gaaagaatca
    24061 ggtgttattg aaaaaacggc catggtattt ggtcagatga atgagccacc aggagcccgt
    24121 atgcgtgttg ctcttactgg tttgactatt gcggaatact tccgtgatgt ggaagggcag
    24181 gatgttcttc tgttcatcga taatatcttc cgtttcacac aggctggttc agaagtgtct
    24241 gccctcttgg gtcgtatgcc atcagccgtt ggttatcagc caacacttgc gacggagatg
    24301 ggacaattgc aggagcgtat tacctcaacc aagaagggtt ctgttacatc tattcaggct
    24361 atttacgtac ctgcggatga ctatacagac ccagctccag cgacagcctt cgctcacttg
    24421 gattcaacaa ctaacttgga gcgtaagttg actcagcttg gtatctaccc tgcggtggat
    24481 ccattggctt cgtcatcacg tgcacttgct ccacaaatcg ttggtgaaga gcactatgca
    24541 gtagctatgg aagtaaaacg tgtccttcaa cgttaccaag aattgcaaga tattattgcc
    24601 attctcggta tggatgaatt atcagatgaa gagaagacct tggttggtcg cgctcgtcgt
    24661 atccaattct tcctctctca aaacttcaac gttgcggagc aatttacagg tatgccaggt
    24721 tcttatgtgc cagtagctga aacggtgaaa ggctttaagg aaatcttgga cggcaaacac
    24781 gaccatctac cagaagatgc cttccgaaat gttggttcaa ttgaggatgt ggtcgctaaa
    24841 gctgctaaaa tgaaattcta gaggtggctt atgggacaaa tgactgtaca aatcgtaaca
    24901 ccagacggta tcaaatatga ccatcatgca gcatttgttt tggtcaaaac ggttgatggt
    24961 gagatgggtg tctattctgg acatgaagaa ctgattgcag ttttggaaat cggtgaaatg
    25021 aaagtgcgtc gtgttgatga tgaaaaccat gtagactgga ttgcggtcaa tggtggaatc
    25081 attgaagtca acaaggatat tattacggtc atttctgatt ccgctgagcg ggaacgggat
    25141 attgatatta gtcgtgcgga acgtgccaaa ttgcgcgcgg aacgtgaatt ggaagaagca
    25201 cagactgctc gtaatattga tatggaaatg cgtgcaacag tcgccctcca acgtgcgata
    25261 aatcgtattc gtgttgggaa acattaatct atatgggatt gaacttggtt cagttccatt
    25321 ttttaatttc atggtataat ggaaacatgg taatttcaat tttacagttt tttagtcata
    25381 tattgtttat ctatctggct catcatctct tggttacaac agttgattgg tcacggtggt
    25441 tgaaggtgac tggggacaat cagcgtaaaa tcaatttgct gattctcttt ctggcaatag
    25501 cactggggta cttagtctcg actttctttt tagaattgtt gatgatggga cgctcttttg
    25561 caaatatgtg atttaagtaa gaaaaggata agaaatggat acaattatta ttacaggtag
    25621 taaaaacggt ttgaaaggac aggttgagat tgagggggcg aagaatgccg ttctgccttt
    25681 attggcagca acagttctag caagtcaagg gcaaaccaaa ttgacccagg ttcctatttt
    25741 gtctgatgtc tatacaatga ataatgttgt acgtggtctg ggagttcgtg tgaaatttga
    25801 cgaggaaaca aagactatcg atattgatgc aacaggtaaa cttggtagtg aaactcctta
    25861 taagtatgtg agtcaaatgc gcgcctctat tgttattctt ggtccgattt tggcacgcaa
    25921 tggctatgct aaggtttcta tgccaggagg ttgtacaatt ggtagtcgtc caattgattt
    25981 gcacttaaaa ggtttgcaag ctatgggggc taaaattaaa caacgcgctg gttatattga
    26041 agcgagtgca gagaacttgc agggagctca tatctatctt gatttcccaa gtgttggggc
    26101 aacgcaaaat ttgatgatgg ctgcaactct ggcgcagggt acaacggtat tagaaaatgc
    26161 agcgcgagaa cctgaaattg ttgacttggc tattttccta aacaaaatgg gggcaaaagt
    26221 taagggggca ggtacagaga cgattacgat tactggtgta gaagaattga ctggcgcaga
    26281 acatcaagtg gtgcaagatc gtatcgaagc gggtaccttt atggtggcag cggcaatgac
    26341 tggtggagat gtcttggtca aggacgctgt ctgggagcat aaccgtccac tcatttctaa
    26401 gatgttggaa atgggagttg aggtgacgga agaagctgaa gggattcgag ttcgttcgca
    26461 agtggataag cttaaacctg taacagtaaa aaccttgccc catccaggat tcccaacgga
    26521 tatgcaggct caatttacag ctctaatggc agttgcaaag ggtgaatcta ccatgattga
    26581 aacggtattt gagaatcgtt tccagcattt ggaagaaatg cgtcggatgg atttgcattc
    26641 ggaaatttta cgagatacag ctatcatcac gggaggactt gctctgcaag gtgctcaggt
    26701 tatgtctact gatttacgag caagtgccgc tttgattctg gctggtttgg tcgctgaagg
    26761 tgaaacgatt gtaggtaaat taacgcactt agatcgaggt tactatcgtt ttcatgagaa
    26821 attagctgct ttaggtgcaa cgattgaacg tgtgagtgga gaagatgaaa atggataagg
    26881 ataatcttag ctatgttggt aaaaatttaa tcttagtagc agttgttttg ttgattgcta
    26941 ttttggtgtt tattttagga ttaatggttg gttacggtgt cataggagat ggagacaatg
    27001 tatttgcggt gttgtcacca gctaagtggc aagaattaat cggtaaattt acaggaaagt
    27061 aggctggacc tgcttttttg atggagagaa aatggcgaag aaaaatgtaa aaaaacaagc
    27121 aatgagtctg ctcagcttat tggctacgat tgttgtagta gcgggtggct atcttttaag
    27181 tgataacaag agtagcaacg ttgctgatta ttcctattat gtcaatcagt ctaaggcaag
    27241 tgaaggcaca cctaatcagg aactggctag ttcggtattg acagaagatg taaaaaagca
    27301 actgggaaat tcgattgaat ggaatagtgc tggagcgttt attattaacg ggaatcaaac
    27361 ggatttagat gcatcggttg ccagtgttcc ttatggtgat aataagacaa aaacagtcca
    27421 gggagaaacg gttccaacag tagccaatgc gcttttagct aaatctacac gtcagtataa
    27481 ggatcgtgaa gaaacaggaa atggtcgaac ttcttggaca cctgcgggtt ggcatcagat
    27541 ccatgattta actggagaat atgaccatgc agtggaccgt ggtcacctcc taggttatgc
    27601 tttgattggt ggattgtctg gcttcgatgc ttcaaccagc aatcctaaga atattgcagt
    27661 tcaaacagct tggtccaacc aagctaacga ccaaacttca actgggcaga attattttga
    27721 aagtcagatt cggcgggcct tggataaaaa taagcgtgtc cgctatcgtg tgaccttggt
    27781 gtatgctgag agtgaagacc ttgttcctgt cggaagtcat ctagaggcaa aagcagcaga
    27841 tggtagccta gagttcaatg tgttcgttcc aaatgtgcag agtggtctca gtatcaacta
    27901 tcatagtggg gaaattgcag taaatcaata aatagtcaga cgaattctcc ctcgttaaat
    27961 caaatatatc agacgatttt cacgtaaaat cgtctttttt tgcgtataat taaaaatatt
    28021 tacaaaaaca gttgacaaat catctgatga atattagaat atagttaaag aaaacgctta
    28081 cgactttgtc gtagaaaaca tttaggagga atttccaatg gaaaaacatg ttgagcaacg
    28141 tgtcgaagac gttacttata acaaagccaa gttatggcaa atcatattat ttgcgatgaa
    28201 caattcatcg acgaatattt acttggttgc ttttactttc gtgacttatt tatcgacagg
    28261 tgtgcttggt cttgcagccc tgtttgttag tcaactgatg gggtatattc gtatctttga
    28321 tggtttcatt gatcctacaa tcggagttat cattgataaa acggatacta agtttggtaa
    28381 atatcgtcct attttggttt tggggaatat cattacagca gcttctcttt ttatgatgtt
    28441 aggtttaagt ggagttagcg agagtctccg tcttcctcta ttcatccttg ttttgattat
    28501 ccataaaatt ggatattcac ttcaacagac gattacaaaa gcaggacaag ttgcgcttac
    28561 caatgatcca aagcaacgtc caatctttaa tattgttgat ggtattgcga caactgtgtt
    28621 gatgactggt agtcaggttg ttgtgtcagg gacattggtt ccaaaacatg gtggtttcac
    28681 tcgaagtttc ttccaagaat tgttcctcgg tgtagtagta atttcagctg ttctgggtat
    28741 tcttgctgtt atcggtattt gggagaaaga caataagaaa tactttggtc ttggtgagaa
    28801 gacacaagaa actaagttga aagactactg gaaagttatc aaaggaaaca aacctttgca
    28861 ggttctttca atctctgcag cttttgtaaa atttgttgct caactgtttg gagattccgt
    28921 tatcagggtt atgctgtatg gtattatctt cggtgactat gctctttctg gtaaaatgtc
    28981 tatgctgttg attttgccag gtattcttgt aacagttggt gctgcgcaat tggctcgtcg
    29041 taaaggttta cgctttgcct atattacagc gcttcaactt gggattgctg gtcttgtgac
    29101 cttggcagcg atgctctttt cagctaaacc aggtatgttg gatttgacaa attggaatct
    29161 ctacacaatc ggcttctttg ttgtttatat cattgctcgc tacgcatcta gtgctccatc
    29221 tggtttggta ttgacaatgg gggcagatat tacagactat gaaacttcag tatctggtcg
    29281 ttacttgtca ggtatgattg ggactatctt ctcattgaca gactcaattg cttcttcatt
    29341 tgccccaatg gttgttggat ttgtattagc aggtattggt tttggtaaag agtacccaac
    29401 cgttgaaaca gcattctcaa cagatttgag aatggctttg attgtcctat tgacagtgat
    29461 tccagcagtg gtattgagcg tatccttgtt cttgatgaaa ttttacaaac tagatcgtga
    29521 agaaatggca cgtattcaag agaaaatcca tgttatgaaa gcggcaaaag atgaggaacg
    29581 tgtgcgtgcg attgcgaaaa atgttccatt atctgatatg gattatgtag atgttactca
    29641 atataaggtt gatcaatacg acgataaata atacaataac gacctagttg gaggattcca
    29701 gctgggtctt tcatctagga ggcggtatga aaaaaatctt agcgtttgga gaagttttat
    29761 tgcggctatc tcctcctcat tatcagaccc taacacaagc taccagttta gattgtcagt
    29821 ttggtggctc agagttgaat gtcttggcca gtttagcaca gttggggcat tcagttgagt
    29881 tggtgacggc acttcctgaa aatgaagtgg gaaagatggc agaacacttt ctctttgcac
    29941 ggcagattgg acagaagcat ctgattcgaa aaaaaggaag gctggggatt tattattatc
    30001 aaaagggctt ctctcttaga cctagccagg tgacctacga ccgtgattat tctgccttta
    30061 gcttatccaa ggaagaagag tatgatttgg aaggtatgtt tgacggtgtc gattggtttc
    30121 atgtcagtgg tataacggtc gctttgaatc cagatattta tcgactggcc tttcgtttga
    30181 tggaaatggc aaagaggcag ggtgttaagg tttcttttga cttgaattat cgagaaagtt
    30241 tgtggtcttc ttttgaagaa gcgagggaga aattatctcc ttttgtaggt ttagcagata
    30301 tttgctttgg tctagagcct attcaactct tcaatgaatc tggaaaagat gtgaaggatg
    30361 aattggggtt gaagcgccct tatgaaaata aagaagtctt gttggcggtg gttaaaggtc
    30421 tggcggagac gtattctttg caaagtcttg cttttaccca gagggaaatg acctacaata
    30481 atgaatattt gctgaaagca tatttgtatc aagatggtat tctttatgaa acggaaaaag
    30541 aatccattca agttttggac cgagttggga caggggatgc ctttacagca ggaattattt
    30601 tgggctattt gcaggaaaaa acgccacagg aaatagtcga cttggggatg gctagttttc
    30661 aattcaaaca taccattgaa ggtgatgtca atgtcatcag tccgtcagat attgctttgc
    30721 tattgaaaaa agggtcacgt gaaataaaac gatagaaaga aggaaaaagt atgttgtatc
    30781 caatacagac aaaaacacgc tcagtttatt ctttaaatgg aatatggaaa tttaagcaag
    30841 ggaacaatga tgttcatact ctgttagata cagatgaggt aatggttgta ccgagttctt
    30901 ttaatgatgt tgttgttgat aaggacaaac gtcgttttgt cggagataat tggtatgaac
    30961 tgatggtagc tcttccagta gtagctgatg atgaagagtt agttgtacgc tttggttcgg
    31021 tgacacatca ggctaaagtc tatgcagatg gtcagttaat cagggagcac aagggtggtt
    31081 tcacaccttt tgaatgcttg attccgtcaa acttatacga cgctgatcaa ttccgtttga
    31141 cggtttgtgc taataatgag ttgaattaca caaccctccc agtagggaat tatagcgaag
    31201 aagtggatga gaatggtcaa attgtgaaga ccgtcaagga aaattttgac tttttcaact
    31261 atgctggtat ccagcggaca gttcatctct ataaacgtcc ccaaaatagg attgaggata
    31321 ttgttattcg gacggagcta aatcaagatt tgactcaggc ggtagtgaat gttgatgtga
    31381 agacagttgg gcagtacgat tccatccgta tgtctatttt agatcaagag ggacaggaag
    31441 taggtcttct tgaaaatgga caaatggtca ttgaacatcc acgcctttgg gaggtcttgg
    31501 atgcctatct ctatactgct aaagttgaat tagttgacgg agaaaactta ctcgatacct
    31561 actcagaaca attcggcatt cgtagtgttg cggttgaaaa tgggcagttt ttcatcaatg
    31621 gaaaaccttt ctatttcaag ggatttggta aacatgaaga taccttcatc aatgggcgtg
    31681 gtttcaatga agcagccaat ctgatggatt tgaatttgct taaagatatt ggagcaaatt
    31741 cctttaggac atctcattat ccctattctg aggaaatgat gcggctggca gatcgtttgg
    31801 gaattgtcgt ccttgatgaa gtgccagcag ttggcctgtt ccagcttttc aatgcagcct
    31861 tgaatttgac aggggattct gaagaagcaa aaaatacttg ggaagttatg caaaccaagg
    31921 aggctcatga gctggtgatt gatgaattga tagcgcgtga taagaatcat ccttctgtag
    31981 tgatgtgggt tgttgccaat gaaccggcag ggcatgaaaa gggagcacgt gcttactttg
    32041 aacctctgat tcagcgcatg agggacagag atccgtctaa gcgtcctgtg accttggtca
    32101 atattatgac agcaacgcct gataaggatg aggttatgga tttggtcgat gttgtctgtc
    32161 tcaatcgtta ctatggttgg tatgttgctc atggtgactt gaaggcggca gagaaagggc
    32221 tccgtcaaga gttggagact tggcaaaaac tttatcctga caagccgatt ttgattacgg
    32281 aatatggtgc agatactctt ccaggtttgc attcgatgtg ggatattcct tatacagagg
    32341 aatttcaggt ggattactac gatatgaacc attgcgtctt tgattcaatt ccgaatttag
    32401 ttggtgagca ggtatggaat tttgctgatt ttgaaactac agtcggtatc attcgcattc
    32461 aaggaaatca caaaggatta ttctcaagaa atagacaacc caagcaaatt gtaagagaaa
    32521 tcaagaaacg ttggactgcc attccaaact accattataa gaggaaatga gctataatag
    32581 tagcaaatag aaagttgtat tggaggacca agcacatggc gaaacccttg gtagaaaaag
    32641 catcagagcg cttattggaa ttgattttgg aaagaggata tgaagttggt gataagcttc
    32701 caaatgagta tgaattggcc caagatttag aagttggacg ttcgactgtt cgtgaagctg
    32761 tgcgaagttt ggctactcga aatattctgg aggtgcgcca agggtcggga acctatatca
    32821 gctctaaaaa aggagtatca gaggatcccc taggtttttc tttggtaaga gaccgtgtga
    32881 agttgacgac agatttgttt gaagtgcggt atttacttga accgagaatt gcggagcgtg
    32941 tcgctcagtt tgcctcggac gaagacattg ctcgactaga agaaattgtc cttgctattg
    33001 aagaggctgt tgctgctgga gacacgaagc atctggagtt ggatgtaaaa ttccactgta
    33061 tgctggctga gatgagtggg aatctggcta tgacaagtct catgcctgtc attaatcaat
    33121 ctattcatct aatcaatgaa aactattcaa atcgtcagat gaaatcggat agtttacagg
    33181 cccacaggaa tatcttaatg gctatcaagc aacgtcaccc tgttgcagca tatgatagca
    33241 tgttagcaca tattatatca gtaagacagg ttgttttaag cgaatggttc gataaagata
    33301 tgaccttgca tggtctcaac gatcataaat agaaataaaa aatagacagc ccagaagaat
    33361 tcttctgggt attttttgct tttttattga caaatcatct gatgaattgt atactatagc
    33421 tataaatgac aacgctttct aattggaggt caagatgtta aagcaattaa aagaaaatta
    33481 ctttttcgca gtgattcgcg gaaaagatga agaagatgcg aaagagatcg ctcgccatgc
    33541 gattttggga ggtattcgaa atattgaaat tacattttcg actccaaatg cagcgacagt
    33601 tatcaaagaa ttacaagagg agttctcaga tgattcatcc gtagtcattg gggcgggaac
    33661 agtgatgaat cttaagctgg cacaagcggc cattgatgca ggtgctagtt tcctggttag
    33721 tcctcatttt gataaagaaa ttcaagactt ggcgcaagag gctgaggtat tctacttccc
    33781 aggttgtgca actgcaacag agattgtcac agctagtcag gcgggatgtc ctattatcaa
    33841 gcttttccct ggtggtgtct tgggtcctgg atttatcaag gatattcacg gccctgttcc
    33901 tgatgtgaat ttgatgcctt caggtggagt ttcggttgaa aatgttgcag attggaaaaa
    33961 ggcaggtgct tgtgctgttg gagtcggttc ggctctggca agtcgagtgc aggctgaagg
    34021 ctatgaaagt gtaacgacga ttgctcgcag ttttgttgca gctttggagg gatgaaatga
    34081 gttttaatga caaaaacttt atgctaaaaa acgagcctgc taaggagctt tacgggaaaa
    34141 tagcagagct tcctatctat gatttccatt gtcatctgga tccgaaggaa atttttgaag
    34201 ataaggttta tgaagatatt gttgatttgt ggctgggggg tgaccattat aagtggcgct
    34261 tgatgcgggc taatggtatc tcagaagaag aaatcacagg ttcagcaagt aaactagata
    34321 agtttaaggc ctgggcaaga accttggaac gggctttcgg aaatcctctc tatcattgga
    34381 gtcatttgga attgcgacag gttttcggtg ttgaggaatt gttgaccgaa gaaaatgcag
    34441 agcgactcta tcatcagctc aatgcttatt tgcaagaaca tcaagttagt ccacggaagc
    34501 tgattgcgga tgttagggtg acctttattg ggacaactga ccatcctctt gatagcttgg
    34561 aatggcataa gcgcttggct gaggactcga ccatagatac tgtagtggca ccgactttcc
    34621 gaccagatga agcttttata gaacatcgaa atttcaatcc atttattaaa cgcttggagg
    34681 aggtaacagg ggtagcagta agagactttg caagttttgt agaggcactt ggtcagcgtg
    34741 tttcctattt tgctcaacac ggttgccgag caagtgacat cagttttacg gctatttcct
    34801 atgaagaggc taccctcgaa gagttggatg aaattttact agcaagactt gcaggtaaag
    34861 aagctggtca atccagtatc aataaatggc agactgctat ctttagagaa ttgtgccgat
    34921 tgtacaagaa acatggcttt gtgacacaag ttcacttcgg tgccttacgg aataaccata
    34981 ccggactgtt tgaaaaactt ggagcagatg taggtgtgga ttcgattgga gaccagacat
    35041 gtctgactgt gaatttgaat cgtttcttag ataacttggt caaggaaaat gcccttccaa
    35101 aaatgatttg gtacaatctc aatccaagtt acaacattgc tctggccaat actttggcga
    35161 atttccagtc caatgaggaa ggggttcgta gtcagctaca atttggtgct ggttggtggt
    35221 tcaatgatac aaagttgggc atgattgacc agatgaatgc ttatgcagaa cagggcatgc
    35281 ttgccaattt cgttggtatg ttgacagatt cgcgtagctt tttatcttat caacggcatg
    35341 attatttcag acgcatttta gcgacctatg ttggtcaatg gattgttgat gaagaagtgc
    35401 cagaagatta caatcgttta gggcaatttg tagaagccat atcctattac aatgccaaag
    35461 agttttttga acaatagaag gagagtaaat catgaaaatg tcatttcgct ggtacgggaa
    35521 aaaagatcct gtgacactgg aagagattaa agcaatccct ggtatgcagg gaatcgtaac
    35581 ggcagtctac gatgtaccag ttggtcaggc atggcccctt gaaaacattc tagagctgaa
    35641 aaaaatggta gaagaggcag gacttgaaat tactgttatt gaatccattc ctgttcatga
    35701 agacatcaaa caagggaagc caaatcgtga tgccttaatc gaaaactata agacttccat
    35761 ccgtaatgtc ggggctgcag gtattccagt tgtttgctac aatttcatgc ctgtgtttga
    35821 ctggacccgt tcagacttgc accacccact tccggatggt tcaacctctt tagctttcct
    35881 aaaatctgat ttagcaggtg ttgatcctgt ggcggatgat ttgaacttac caggttggga
    35941 ttcgtcctat tccaaggaag aaatgaaggc tattattgaa aattatcgtc agaatatctc
    36001 tgaagaagat ttatgggcga atttggagta ttttatcaaa gcgattctgc caacggctga
    36061 ggaggctggc gtcaaaatgg ccattcaccc tgatgaccct ccgtatggaa ttttcggatt
    36121 gccacgtatt attactggtc aagaagccgt tgaacgattt ttgaatctct atgattcaga
    36181 acacaatgga attaccatgt gtgtcggatc ctatgcttct gatccgaaaa atgatgtcct
    36241 tgccatgacg gaatatgctc tcaaacgcaa tcgtatcaat tttatgcata cgcgcaatgt
    36301 gacggcaggt gcttggggct tccaagaaac tgcacatttg tcacaggctg gtgacattga
    36361 tatgaatgct gttgttaaat tattggtgga ctatgattgg caaggttctt tgcgtccaga
    36421 tcatggtcgt cgtatctggg gagatcagac caagacaccg ggctacggtc tgtatgaccg
    36481 agcgctcggg gcgacttact ttaatggtct atacgaagcc aatatgcgag cggctggcaa
    36541 aacaccagat tttggtatta aagcaaaaac agttggaaca aaggagggat aactatgacg
    36601 cgtgtcattg aatttaagga caaggttgtt gtcattacag gagcaggcgg agtactttgt
    36661 ggttatttag ccaaggaatt tgctaaggct ggtgccaagg tggctctttt agacttaaat
    36721 caagcagcag cccaagtttt tgttgatgag attgttgcag caggaggtag tgccaaggct
    36781 tacaaatcta atgtcctttc caaggaaaat ttggaagaag ttcgccaaca ggtattggca
    36841 gatttcggtc cggtagatat tttaatcaac ggagcaggtg gcaataatcc gaaagcgaca
    36901 acggataatg agttccatga agtgggtctt ccagcggata cgaaaacctt ctttgaccta
    36961 gatgaggcgg ggattaactt tgttttcaat ctgaattatc taggaacctt attgccaaca
    37021 caggtctttg cacaggatat gattggccgt agcggagcaa atattatcaa tatctccagc
    37081 atgaatgcct ttactccttt gacaaaaatt cctgcctatt caggtgctaa ggctgccatc
    37141 agtaatttta cccaatggtt ggcagtacat ttttcaaaag ttagtattcg ttgcaacgcc
    37201 attgctccgg gatttttggt aaccaaccaa aaccgtggtt tgctttttga cgagtcaggt
    37261 caaccgaccg cacgtgccaa caagattttg accaatacac caatgggacg gtttggtgaa
    37321 tcggaagagc tagtcggcgg cgtcttcttc ttggcagatg agaatttggc aagttttgtc
    37381 aacggtgttg ttttaccgat tgacggtggc ttctcagcct attcaggagt ctgatgatga
    37441 agatggaata cgtattttgt gtggactctg atggctgcgc catggacacc atgacctaca
    37501 aacataagct tttcttcggc cccttagctg cggaagtttt tggtgttgaa gataaagaac
    37561 cgtttttagc tgaatggaat cgagttaatc tctactcacg agaacgtggc attaaccgtt
    37621 ttgttggctt agttaaaggc ctagaatttg caggtgtgac tggtatagac aacttgaaaa
    37681 attgggtcgc gaccacagat tctttgtcaa atgcttctct ggaaagattg atagaggagc
    37741 agccgtcaaa agacttggaa ttagccttaa aatggtccac tcaagtcaat caagccatta
    37801 agcattatag tggtcctgtt ttagccttca tcggcgttca caagggcttg gaaaaattga
    37861 gccagttagg aaaagtctac gtagtttctt ctgctaataa ggaagcagta gaagaagagt
    37921 ggacagacca aggtttgatg gactttgtta cagaattgta ctgtcaagac cgtggcaaga
    37981 aagaagatgt catcaaactg ttaatagagg aagggtattg tcctaataag attatgatga
    38041 ttggtgactc gcctggtgat ttgaaggcgg cggaattgaa tggtgtccat ttctatccta
    38101 ttttagtagg acgagagatg caatcttggg cagatttgac agaaacgatt gcagatgact
    38161 ttgctcatca agcattcaca ggtgagaaag aaacagaatt gatacaggca ttttggaata
    38221 atttagacga ctagagaagg gctagaggcg ctatgccctc tagctttttt ggaggcaaac
    38281 atgacacatt tagtagattt acggaagaaa ccttacagcc ttgatgaaga ggctatttct
    38341 tggattgaag aaaccattgc tcagatgacc ttggatgaaa aaatcggtca cctctttgtc
    38401 aacatgggga gccagcggac agaagactat ctgactggag tattaaatga ttataagatt
    38461 gctgctgttc gttacaatcc tggacctgct gcagatattt gggagcaaaa ctatattttg
    38521 cagaccaagt ctaagattcc cctcttgatt gcagccaata ccgaatctgg tggaaatggc
    38581 gctgttacgg atggaacgaa aattggggat gaaatcaaga ttgctgcgac aaccgatccc
    38641 cgctatgctt atgaaatggg gaaagttgca ggacttgaag cagctgcggt aggctgcaat
    38701 gcctcctttg caccgattat ggacctaagc cgtaattggc gcaatccaat cattgcaaac
    38761 cgaacatggg gagctaatgt agaccaagtc attgaattgt ccaaagaata catgcgaggc
    38821 attatggaac atggcattgt gccgtttgct aagcattttc ctggagatgg tattgacgaa
    38881 cgagatcatc atttgtcttt cgcttcgaat cccatgacca agtctgaatg gatggaaaca
    38941 tttggacgga tttatggtga gatggctgac gcaggtctcc caggtattat ggcggggcac
    39001 attcatttgc caaatgttga gaaagaaatg catccagaac gtgaattgga tgacatgttg
    39061 ccagcttcgc tgaataaaac cctcttggat gaattgcttc gtggagagtt aggttacaat
    39121 ggtgccattg tcacggatgc cagtcacatg atcggtatga cagcctctat gccgcgtcgt
    39181 gagctattgc ctacagctat tgaggcagga tgtgatcttt tccttttctt caacgatcca
    39241 gaagaagatt tgcaatggat gaaagaagga ttggaaaatg gtctgctttc tgaggaacgc
    39301 ctccatgatg cccttcgtcg taccttgggc ttgaaagcta aactcggtct tcacttgttt
    39361 gaaggtcgtc gtcaggaaat catgttgcca aaagaagaag cactggcttt gattggtaga
    39421 gatgaggcga aacagcttgc aaaagaagta gctgacaagg cgattacctt ggtaaaagcc
    39481 aaacaagaag gaattttccc agtcaatcca gaacgctaca aacgtatttt gttggtcgaa
    39541 gtagatggct ataagggtgg ttttggtgcc atgatcaatg ctggcaagaa gagagcagcc
    39601 gatacgctga aagaactatt agaagctcga ggtcaccaag tatctatctg ggaaaatacg
    39661 gaggcacgga ttgccaaatt gccagaagaa gaaagaccag cagcgattgc aaatgtctat
    39721 gcttccaagc gtccaattgc ggaaatcaca gataactatg atttgattat caatttagtt
    39781 gatgtcaact caggaggaac aactcagcga attatttggc cagctgccaa gggaacacca
    39841 gaccagcctt tctatgttca cgaaattcca accattattg tctctgttca gcacccattt
    39901 gcacttgcag atatgccaca ggttgcaacc tatatcaatg cctacgatgg cttgcctgtc
    39961 acattagaag ccttggttgc taaactagca ggagagtcag cctttacagg agtatcgcct
    40021 gttgatgcct actgtggctt ggtagataca cagatttggc gcggaaaata aggaggaaag
    40081 aatgcctaga ttggttgatt tgcggaagaa accctattgt ttgaatgatg agcagattac
    40141 ctgggtagaa aataccttgg ctcatctgac tgatgaagaa aaaatcggtc aattgtttgt
    40201 taatctattc ttcttcggag gagacgcttt tagcggaaat aatctgagta atcaggaatt
    40261 gatgaatcga taccacatag gtggtgcccg ttatatgaat ggcagtccag aacaggtaca
    40321 aggactgatt aacgagctgc aaagctattc aaaagtacct ctcttggttg cagcgaactg
    40381 tgactcaggt ggagatggag ctgtgaaagg aggaacctat atttcctcag gtgctcaatc
    40441 ggaagccagt cgggatcctc gtattcccta cctagcaggt ctcgtatctg cgcgtgagga
    40501 gactgcatta ggtgtaaatg tcaattttga tccttgcgtg gacattgttc agaactggcg
    40561 caatactatc gtcaatacca gagcctacgg tacaaatgcg gatgatgtta ttacctatac
    40621 cagtgcctat ttagaaggat tgactgctga aagagatgtt attcaatgta tcaagcattt
    40681 cccaggagat ggtaaagaag aacgtgatca gcacctagtc ctaggcgtca atgagctctc
    40741 tccagaagaa tgggacaaga gctttggtcg tgtctatcgt catcatattg aagctggtgt
    40801 tgagatgatt atggcgggac atatagcctt gccatattac caacaacgac tcaatccaag
    40861 tttgacggac gaagatattt tgcctgcaac gctggctcct gaattgatcc aagatttatt
    40921 gaaagaaaaa ctggaattca atggcttggt cataacagat gccagccaca tgttggggat
    40981 gacagcagcc atgcgtcgtg aagactacgt acctgcagcc attgctgcgg gttgcgatat
    41041 gttcttattc ttcaataact tagaagaaga ttttgaattt atgctcaatg gctaccgcaa
    41101 gggagtgatt actgacgaac gccttcatga tgctctccgt cgcattttag gtctgaaagc
    41161 caaactcaat ctgcatatca agcaagcgga aggaacctta ctaaaatcag ctgatgaatt
    41221 ggctattatc ggctgtgaag aacacttggc ttggcaacgt gaggcggcag acaaggcaat
    41281 tacgctgttg aaagatacac agaaaaatct tccaatcagt ccagaaaccc atcgcagaat
    41341 ccgattgtat tacctagaag gtgaaaaaga agggattatg gcggcaagta cagaagtggt
    41401 tgataacctt aaagctgcct tggaagcgcg tggctatgaa gtgaccgtca atgatggtac
    41461 gactcggatc aaaggaaaaa cgctgcaata ccgagaagaa gttgatttag ccttgactgt
    41521 tgccaatgtc attggatatg gagcgcagaa taattaccgc atccagtgga aaacggccat
    41581 gtcaaatgaa gttccttggt atgtacatga agttccaacc attttcattt cactaaacta
    41641 tacaactcac cttcacgatg ttaccatggt caaaactgct atcaatgcct accatcacaa
    41701 taaaaatact atcgaatcct tacttgataa attagaagga aaagacgcat tctttggtgt
    41761 gccaaatgag aatgtttggg ccaataaatg gcaggcaaaa ctataaaact aaactccttt
    41821 ctatcctaga tagagggagt tttctaggaa gatttcttgc caaactttct tctttttgat
    41881 aaaatatcct taattgaata gaagtctgtg agactagtac accttatgga agctgtccag
    41941 ggagttgagc cgtgactgca agctcaatca gtgaaagttg gtcgaattca ctcacacaag
    42001 gacttagaac ctgcattcac agttcaacac ttccatctaa ggctagtttt tcagctactc
    42061 atcgttagtt tttttcaaaa tacagtcagt attccctcaa aaaacagcct tgattagcgg
    42121 aaaaccatct cttatgtgca agcacttcac ttgtgaatat aggttcatag aactaaggtc
    42181 tgccttgcag atgaaaacgg atggtaccgc gtgacaacgc tccgatacga gtggtgtcat
    42241 gcgtttttta ttggaggaat tatgtcaaac attgaacaac agttggctga attaagccaa
    42301 acgacactag aaaagttaaa agaaatccag caccaaggag aaaaagaact acaagacctg
    42361 cgtgttgcgg ttttgggtaa aaaagggtct ttgacggact tattgaaagg cttgaaagac
    42421 ctgtctaacg acatgaaacc aatcgttggt aaacaggtta atgaagtgcg tgatgtgctg
    42481 acaactgcct ttgaagaaac tgctcaaaag gttgcagcag caaaaattca gcaacaacta
    42541 gcttccgaaa ccattgatgt gaccttgcca ggtcgtcagg ttaaggtcgg aaaacgccat
    42601 gtcttgaccc aaacttctga agaaattgaa gatattttct tgggcatggg cttccaaatc
    42661 gttgacggat ttgaagtgga aaaagactac tacaactttg agaggatgaa tttgccgaaa
    42721 gatcatccag cccgtgatat gcaagatacc ttctacatca cagaagaaat ccttatgagg
    42781 acccatacgt cgcctgttca ggcgcgtacc atggaccagc atgatttctc aaaaggtgct
    42841 ttgaagatga tttcgccagg acgtgttttc cgtcgtgata cggatgatgc gacccacagc
    42901 caccagttcc accagattga aggcttggtt gtcggtgaaa atgtatccat gggcgatctc
    42961 aaaggtacgc ttgaaatgat tatcaagaaa atgtttggtg aagagcgtca gattcgcctg
    43021 cgtccatcat acttcccatt cactgagcct tctgttgagg tggatgtttc ctgcttcaag
    43081 tgcggtggtg acggctgtaa tgtatgtaag aaaacaggct ggattgaaat cctcggtgcc
    43141 ggcatggtcc acccgcaagt attggaaatg agtggtattg actcaaccaa gtactctggc
    43201 tttgccttcg gtcttggtca ggaacgcatt gccatgctcc gttacggtat caacgacatc
    43261 cgtggtttct atcaaggtga tgtacgattc tcggagcagt tttgatgtga gacctgtttc
    43321 tgatactgaa agtatctaga aacaggacgg tagccgctat ggcggtctac ctactcccct
    43381 cactaggttc aaggttgaaa aatatgtcgt tttcaacctt gaaccgtcgt aatctcgcac
    43441 tatttaaggt gtgggtatcg ttgctctgcg actttcctag tccagttaga aatgagaggc
    43501 aatgagatgc agattgatcc tatacgtttg gaagaggttt ccgttttgca ggagttggcc
    43561 aagcagactt ttgcagagac cttcgctcac gataatgacc cgaaggaact ggaggcattc
    43621 tttgaggaat cttattcctt ggaggtcttg actagtgagt tatcggatcc caactgccag
    43681 cactattttc taagaataga tcatcagata gctggttatc tcaagctcaa caaaggttct
    43741 gcccagacgg agcaagagtt ggaaaatgcc tttgaaatcc agcgtatcta tctcttgcag
    43801 gcctatcaag gtcgcggtct tgggaaggtc ttgtttgaat ttgctttgga aaaagcagag
    43861 cagtctagtt gtgattgggt ctggctggga gtttgggaac ataattacaa ggctcagaaa
    43921 ttctattcca aatacggatt tgaaaaattt ggccagcatg aatttgcggt cggtgataag
    43981 attgatgtgg attggctact gaaacggcct ttgcaccaga aaggataata tgttagtaag
    44041 ttacaaatgg ttaaaagaac tcgttgactt tgatgcgaca agccatgact tgtctgaaaa
    44101 aatgtcaaca acaggaattg aagtagaagg ggttgagcaa aagagtgctg gcctttctaa
    44161 gttggttgtc ggtcaggttg tgtctgctga gccaattcca gatactcacc tcaatatttg
    44221 tcaggtaaat gtgggcgaag caatcacgca aattgtttgc ggtgctccaa atgtcaagcc
    44281 aggtatcaag gtgatcgttg ctctgccagg agctcgtatc gctggcaact acaagattaa
    44341 gaaaggcaaa atccgcggag ttgaatcctt gggcatgctc tgctcattga gcgaaatcgg
    44401 cgtgtccgac tcagttgtgc caaaggtcta tgcggacggt atctaccacc tgccagaaga
    44461 tgcagtcgtg ggtgagccag tcttttcata tcttgacctc gacgacgaga ttattgagtt
    44521 gtccatcaca ccaaaccgtg ccgacgccct ctctatgcgt ggtgtggctc acgaagtggc
    44581 agctatctat gacagcaagg tcaacttcaa gccagtggtc ttggaggaaa gcgacaagaa
    44641 agccagcgat gtgattgaag tggccattga gtcagacaag gtgactgcct acacggcccg
    44701 tgttattgaa aatgtgacta tcgcaccgag cccgcagtgg ttgcaaaacc tgctcatgaa
    44761 cgcaggtatt cgcccgctca acaatgtggt ggacatcacc aactacatct tgctctactt
    44821 cggtcagcca atgcacgcct ttgatttcga taaatttgaa ggcaagaaaa tcgtggctcg
    44881 tcaggcaaaa gagggtgaga acttggtaac tcttgacggc gaagaacgtg acttgattgc
    44941 cgatgacatc gtcatttccg ttgcggacaa ggcagttgcc ctcggtggtg tcatgggtgg
    45001 tgctagtaca gagattgaca atagctctaa gaccgtcgtg ctggaagcag ccctctttga
    45061 cggcaagtct atccgcaaga cctcaggtcg cctcaacctt cggtctgagt cctcttctcg
    45121 ctttgaaaaa ggcatcaacg tagcaacttt gacggaggct atggacacag cggctgctat
    45181 gattgcggaa ctggctggcg gtcaggtctt gtctggcatc gtttctgcgg gcagcgtgga
    45241 cacttcggat gtcccagtca cagcaaccat tgattacgtt aaccgctcgc ttgggaccaa
    45301 cctcgactat gcccaaatcg cagatatttt ccgtcgttta ggtatggaaa caactggcga
    45361 tgcaagtcag tttacagtag cagtaccgcg tcgtcgttgg gacattcgca ttccagcaga
    45421 cttggtagag gaaatcgctc gtatctatgg ttacaataat ctgccgacca ctcttccgaa
    45481 agaggacgga acagcaggcg agttgaccct gacccagaac atccgtcgcc aagtacgtag
    45541 cctggctgaa ggtgcaggtc tgacagaaat catttcctat gccttgacaa cgcctgacaa
    45601 ggctgtggag tttgtggctc gtccaaccac agtcaccgaa ctcatgtggc cgatgacagt
    45661 tgaccgctct gccctccgtc agaacatggt gtctggtatg ttagacacag tggcctacaa
    45721 cgtggctcgt aagaacaaga atttggctct ttacgaaatc ggtaagatct ttgaacagtc
    45781 tggcaatcca aaagaggacc tgccacaaga aatcaacaag tttgcccttg ttttgactgg
    45841 tttggttgct gagaaagact tccagacacc agctgtacca gttgatttct tccatgccaa
    45901 agggattttg gaagctatct ttgatcatta caagttggca gttgactttg tggcgactag
    45961 tgagattgct gccctgcacc caggtcgtac agctgaaatc catttgaatg gggctgtgat
    46021 cggctttgtc ggtcaggtac accctcaaac ggctaaggac tacggtattc ctgaaactta
    46081 tgtggctgaa atcaatctgg atgcgattga agaagccctc cagcctgctc agccatttac
    46141 cgacatctct aaattcccag cggttagccg tgatattgcc ctgcttttga acagcgatgt
    46201 caaacatcag gatgtcctgg atgccattgc tggtgctggc gtgaaacgct tgaccaaggt
    46261 gactctcttt gacgtctatg ctggcagcaa tatcgaggtt ggtaagaagt ctatggctta
    46321 taacctgacc ttccagaatc ctgaggatag cttgacggat gaggaagtgg ctaagtacat
    46381 ggagaaaatc agtaagtcgc tcgaaacact tggagctgaa attcgttaac atgtaaatct
    46441 tgtgaaatcc tagtcagcgg gctgggattt tttggaggga agtatgaaca ctcaagatat
    46501 tcaagaaaaa ttttttcgag aaggcaagct tatcgttatt cctaaaaaat taaaaagtaa
    46561 gcaagtttta tttgcctatt tacaagaaga gttggctaag aaaggctcta ccttcacaga
    46621 aaaagaagtc aatgcctttc tagctgaagt ctatgatgat tatgctatat tgagacgcta
    46681 cttggtggac tacggctact tgtcgcgtga ccaatatggt ttggaataca gaatagaaga
    46741 aaagagatga ttgcggtcat ctcttttgtc ttacaaaata aagggttcaa tcttcaactc
    46801 tatctggttg ccatacttgg ctagtaaatc gtctgccagg ggatgataga gttctcgtag
    46861 ttgttcgatc ttgtcaggaa attgtttgcc gatgtagtca aacttgcact cgatggttaa
    46921 gaaaagttgg tggaagagtt cgttaatctc attcaagcgg gcaatcattt cttcgtcttc
    46981 tttgagaaaa tcagggattt ctgagcgatt gttgacaaaa ccgtcgatga gttttacggg
    47041 gaaagagccg tattctagga caaattcgta catgggtttc tccttgcctt actattgata
    47101 ggactattgt agcatagatt agaatgtgac aaaagaattt caactttatt gcagtttaag
    47161 ttttgtttaa ttttattttc agtttcattt aaagctaggt cggtaaacta tatcttgtaa
    47221 acaagacagg gacctgtcaa aatttaggat agaagaggca caataatgaa aacaagaatc
    47281 gtacaaaagc agtttaagcg taaagagact aaatatatcg ttgataaaaa aacttttgaa
    47341 cttttagaaa aggaacttcg tcagtacatg atggcagatg agtttgcgac atcaacgatt
    47401 accaatatct actttgataa tgaagatttt gatatgattc aagattcact tgccaaaaag
    47461 aatggacgtg agaaaattcg gatgcgtgtc tatgatgcga caccatctga atcgagtcaa
    47521 gcttttcttg aaatcaagaa aaaagaaaat aaaattggct ataaataccg tttaacttca
    47581 aaccctgttt ctgtagcaaa ttatatcgaa aatggagtga ttgattccac aatcaaggat
    47641 gataaggtaa cctcagaact cgaaatgttg agagaacgct acggtactat taagccgaag
    47701 atgtatatct actacgatcg cgtatcctat aaaggaatcg aagacaaaaa agttcgtctc
    47761 acaatcgata agaacttact ttatcgagac tacgatgtgg atgcaatgga aggtaaattt
    47821 ggtaagaacc tattagaccc aaccaaagta atcatggaag taaaagttcc agaagaacga
    47881 ccagactggt tggtagccct gctcgaaaaa taccaaatcg aaaagcaatc attttcaaaa
    47941 tatggcaatg cctataagct tgcccacaac atcactggag aggaagtaag caaacatgca
    48001 gctgtttaat agtatctttt caacggccaa tagcaatatt accttagcgc aaatgtccat
    48061 ggtttttgga gttagtctat ccatgggggt actcttagcg gctgtttata aatataaatc
    48121 taattataca aaggaatttg tcatcacact aagtctgatg ccggcattga ttgctgttat
    48181 cattgcatta gttaatggta acttgggagc gggtgttgcg gtagcaggga ctttcagtct
    48241 aattaaattc cgctcagcag caggttcttc gaaggaaatg cttgcagtcc tcttagcgat
    48301 ggctatcggt ctagcgacag gaatgggctt cctaggtttg gctgtcttta tgacggtcat
    48361 cctatctgct tgtattttga tttttgagaa catcagcttt gctcaagtca atcaaaatcg
    48421 tcgtcatctc ttggtaacag tgccaatgaa ttttgactac gaccaatttt ttgagaaaca
    48481 atttggtaca tcctgcaagc aagcggatct catttccctc aagtacaaga agaaaaaaga
    48541 agcgctgatc ttagaatatc aagttctcct cgataaaaaa attacagata aacgcttggt
    48601 agatacagta ttgtcagccg gtcctttgga tgtcgtattg aacaagcaaa tgccgaagaa
    48661 gaagtatttg taatatcaaa gaagccctgg atttccaagg ctttttcgtt ttttattagc
    48721 ttattcttca taaaaatcaa cgctataatc aagcaatttg tccccatcat agcggaagca
    48781 agcggaaaaa aatggtttgt cctctaatag ccattcttga aaatgccggt cgccctccca
    48841 agttggtttg gacaagactt ggtcataggg aacccactct aagtcacctt cattgcagtc
    48901 aataagactt ccttcaaaac cagttatctt aaagacatag gtgtaccagt cagtgtttgg
    48961 agtaaagtct gggaaggtta tcactccttt tagagcatgc ttcgttacag taagcccagt
    49021 ttcctcaaag atttctcgaa tggcacaagc ctgcggtgtt tcaccgggtt ccagcttacc
    49081 accgacccca atccatttcc cctggtggac atcgttttct tttttattgc gatggagcag
    49141 gagaaattct ttgccattat caatgtagca aatcgtagcc agttggacag gtttcttggt
    49201 catagtagct ccttatagtt agtttgttcc tattatatca caaaggcggg agtagggaca
    49261 cctgcttggt gctctggtag gggacagttt tgggattagc atactgaaag ctcttttctg
    49321 aaaacagttt ttgaggtata ataagaacat caaactattt aggatgcact atgtcaaaac
    49381 aagaacaaat cgaacaaaca atttatcaat tattggaatt attgggtgag gacccgaatc
    49441 gtgaaggttt attagatacg cctaaacggg ttgctaagat gtatttagaa atgtttaacg
    49501 gcctagaaga ggatcccaaa gaccaattta cagctgtctt ttcagaaggt catgaagagg
    49561 ttgttttggt caaggatatt ccttttcatt ctatgtgtga acaccatttg gtaccctttt
    49621 atggcattgc ccatgtagct tatattccga gtaaggggcg tgtgacaggt cttagcaaat
    49681 tggcgcgtgc agtggaggta gcaagtcgtc gccctcaatt gcaggaacgc ttgacccatc
    49741 aggttgccca tgcccttcaa gatgcccttg aaccagaagg tgtttttgtc atggtcgaag
    49801 cagagcacat gtgcatgagc atgcgtggta ttcgcaagcc aggtagtaag acagtgacca
    49861 cagttgctct tggcaaatac aaggaagatg ccatcttgcg ccgtgaactc ttgtccatga
    49921 ttcacaataa ataggaggtt ctatgtcaat cgaacagtta gcgaatcaag taaccattat
    49981 ggggattctc aatgtgacgc cagattcatt ttcagatggt ggtcactata atgaggtgga
    50041 gtctgccttg gtacaagtag aaaagttgtt ggctgagggt gctaccgtca ttgatgttgg
    50101 tggtgagtcc actcggccag gtgcaacatt tgtgtctgaa gaagacgaga ttgctcgcgt
    50161 ggttccgatt atccgcgcta tcaaagaaaa ctatgactgt cttgtcagcg tcgataccta
    50221 taaaacagga actgcacgtg cagccttgga agcaggcgca gatattttaa atgatgtctg
    50281 ggcaggactt tatgatggag atatgttggc cctggctgcg gagtacaagg taccaattat
    50341 tctcatgcac aaccagaaag acgaaagcta tgcggatgtt gttggagagg tcaaaaactt
    50401 tctagctgag cgtgcccaag cagcacttga tgctggtgtt tccgcagacc agatttggtt
    50461 ggatccagga tttggctttt caaagaatgt ccaacataac cttgatctct tacaaggttt
    50521 ggaacagatt actgcccttg gttatcccgt tctatttgga atatctcgta agcgcgtggt
    50581 ggattatctg cttgggggca atagtttacc gactgaccgc gatcaagcaa cggcagcctt
    50641 gtctgcctgg gcagtccaaa aaggctgtaa aatggtccgt gttcacaatg tcgctgccaa
    50701 ccgtgatatc gttaaggttt gggaccaatt gacttctgga ggtcaacatg gataagattt
    50761 ctctcaataa atgtcgcttt tacggctacc atggtgcctt caaagaagaa caagttcttg
    50821 gtcaaatttt cacagttgac tgtgatttgt ttgttgacct gacagcagct tcacaaactg
    50881 acaatttaga agacacagtt cactatggta tggtctttga aaccattaaa gcagttgtgg
    50941 aaggcaagcc ctatattctc attgaaaagg tggcaggtgt catctgtcag gagatttttg
    51001 atcaatttcc aaaggtggag aagattcgct tggccattta caaggaaaat ccgcccattg
    51061 ctggacacta tgattctgtc ggaattgaat tggagcgtga acgaccatga agcatctagc
    51121 ctatctcagt atcggaggga atatgggcaa tcgacaagcc tatttacagg cagccctaga
    51181 caaattagcc agtcatccag gttgccagct tggcttagtt tccaacattt atgaaactcc
    51241 agcttggggc aagaccgacc aggctgattt cctcaatcta gcctgtcaag tgtatactga
    51301 tttgtctgct caggattttc taagcgtttt ccagaacatc gaacaagagt tggaccgagt
    51361 acggattgaa aaatggggac aacggaccat tgatttggat attatttttt gggatgagga
    51421 gaagattcaa gaagagaatc tgattgttcc ccatccctac gcccatgaaa gagcatttgt
    51481 tctcaaacct cttgctgaga ttgcttctga ttactgtcac ccaattttga aaaaagtggt
    51541 atcggacttg cttgcagaac taggggaaca aaaagatata aaaattttca aatagttgcc
    51601 tctgatacta ggtttattag aggatagaat agataaagga gttttatgac aattttagca
    51661 actttaggag ttttattggc tattgtagcc attatttatt ggacatcaaa aaatttacat
    51721 gttatcattg ctgcaccact cgctagttta atcatcattc tgaccaatca gatgaatgtt
    51781 ttggaagtta tgttgggcaa agagcagtct tatatggcgg gcttagcagg ttttttgatt
    51841 aataattttg ccatctttat gttggggtct atcttggcac gttatatgga ggcaagtgga
    51901 gctacgcaga cgatcgccaa tagcattttg aaggtaatgg gaaaggatag tccctataag
    51961 ggcttgttag ctatcacttt gattgcttcc attctgacct atggtggtgt gagtattttt
    52021 gtagttattt ttaccttgct tcccctttca cgccccctct ttaaagagtt gaatatcaac
    52081 tgggcacttt ttccgattcc tgtctttttg ggagcaggta cctatacgat gacaactctt
    52141 cctggggcac cttccatcca gaatgtcatt ccgacaaaag ttttgggaac tagcttgacc
    52201 gcggcaccca ttatcagttt ggcagccagc ttgacactat tagtatttgg cttgctctac
    52261 atggcctact gcctcaagaa aagtctagca aatggagaga cgtatacgga agaagaggat
    52321 gaaactgcag tagtggtagc tgataagaca ccaaatctat ttttatcagt cttgcctcta
    52381 ttcagtctta ttgggacgat tttcctaatg agtaaaactc cgaatgtcct ggcaatcgga
    52441 ttgttggtct ctatccttct atcagccttg attttttatc catatctgcc aaatcaaaaa
    52501 gaaattttga atgctgcgac aacggcatct atagtgcctg cttttgcaac ttctagtaca
    52561 gtagcctttg ggactgtgtt aactttgtca gcaggttttg cagtcattca agaatggatt
    52621 caacaaatac caggatcacc tctaatcagt ttatctgttt cgacagcatt gattagtggt
    52681 attatcggtt catcttctgg tgcgataggt attgcttcaa gtaatttcct tccttcctat
    52741 ttggaaatgg ggattaatcc ggagttgctg catcgtgtag tagtagttgc atcggctatt
    52801 ttgacagtta tgcctcagtc tggtgtgatg attaccttcc acaatctttc gaaattaagt
    52861 atgaaacgtg gcctcaagta ttcgtttatc ctagtgacag ttgggcattt gttagcatta
    52921 tttgtgattt tactgttggc acctttgcta tattaggatt gattaacaaa caaataaaa
//
LOCUS       DBNFCO010000005        45055 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.005, whole genome shotgun sequence.
ACCESSION   DBNFCO010000005 DBNFCO010000000
VERSION     DBNFCO010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 45055)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45055)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45055
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.005"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            <1..792
                     /locus_tag="AC1PIV_000251"
     CDS             <1..792
                     /locus_tag="AC1PIV_000251"
                     /inference="COORDINATES: protein motif:HMM:NF027869.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilin N-terminal domain-containing protein"
                     /protein_id="HIP6611307.1"
                     /translation="IKHLVHAEDTASTTVIVHKIVMNNDDFNKFTYEENLSKYNGNSI
                     GDLKNYFGNSAVEVAGVKFDVWKKTDVVAPEAKTGAELGITGDTNKYVKTDKTAMTQD
                     NGATFTLANGIYIFTEDKENSPYYNNQNELTGMKAVPFKLELPQAKTDGSGYFDTKTP
                     LHVYPKNTENKPEITKEFTDKRTNVDQDGIKNVEIGQEIGYTITTKVPKDAAYKTFAW
                     EDTMLAGLDFKLNSLQIADNKNLNLCSRYRLHIDTNCTWIHGEIE"
     gene            776..1885
                     /locus_tag="AC1PIV_000252"
     CDS             776..1885
                     /locus_tag="AC1PIV_000252"
                     /inference="COORDINATES: protein motif:HMM:NF027884.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HIP6611308.1"
                     /translation="MVKLNNNGLAKLEEKAREGEVNFTLTYKATLNDSAKVETEIPNQ
                     VKLIYGNRPSEFSEPKSTTPKDGEIIVNKTWDTGVNQTEVVFGVYEKGTGVRVGEIKL
                     AAGVNTGKLTGLDGAKEYIVIEETIVSGSLPSYSNGDTGTIRIENKKNPNPTPLTPED
                     PKVVTYGKRFVKTDDKDLDSSEKLLGAEFIVRKDGEESYLALKDTVTQAKEIADYKAA
                     EADYLATVKSATTDNPKIDEIKQKKDARDTAYEKMNMQWTWVGTKEGAFTFVSSTDGK
                     FEVKGLKEGKYELIETKAPEGFALPTSPVEFTVGAHTWGTIDALTADNFQQIKNKKVT
                     IPQTGGIGTLVFTIVGLSTMVFAFIAMKKRQSEEA"
     gene            1909..2763
                     /locus_tag="AC1PIV_000253"
     CDS             1909..2763
                     /locus_tag="AC1PIV_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prealbumin-like fold domain-containing protein"
                     /protein_id="HIP6611309.1"
                     /translation="MKTVRQIICCLVAIICVLSLPSLSLQAQDSFDVQVHIPFPNGID
                     ASQVSTGLEAWYIASEEPVSSEQLADSLYQKSRSELTSLYGEPISSQALSPEGQATFR
                     GLTKGWYYVRQVGKPTSLEVIPFLMNVGRGVTKIEAKVRRPSEEKGSKPFLKVSTSTA
                     PLSGAEFAVLEEVGGELKEVIVDGNSYHVTSSSNGQFVVGPLPYGTYYLKEVKAPTGY
                     ILSQDTIPFEITSDSHVSEIIKIKNKPVTPPGIEIPYTGNVVVIAVLSTGILLFLLGY
                     RLVTYTKR"
     gene            3036..3923
                     /locus_tag="AC1PIV_000254"
     CDS             3036..3923
                     /locus_tag="AC1PIV_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HIP6611310.1"
                     /translation="MIQKKSGKTTKKKKKSNIPFYLVFLIGFGILLYPHVSNFYYRYE
                     SDQLTNSFDQEKKTLASEEVKERIDLAQAFNESLNNVVSEDPYTKSRHEAGRVEYARM
                     LELHEKIGYVEIPKIEVKLPVYAGTSETVLQKGVGHLEGTSLPIGGSDTHTVLTAHTG
                     LPKARLFTDLTKVKIGDTFYIHNIVETLAYEVDQIVVAEPTQFEELLVKPGQDYATLL
                     TCTPYMVNTHRLLVRGHRIPYVAEEHLKASENAEKRILIRYLLYALGMFVGILLIFLL
                     TKRRKNKKKVTSNDETFTT"
     gene            3901..4758
                     /locus_tag="AC1PIV_000255"
     CDS             3901..4758
                     /locus_tag="AC1PIV_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HIP6611311.1"
                     /translation="MMKRSQLRKGISKQSILLKLLFLFGLVVTLYPWISQYYYRYDSD
                     YKIQSFYEQAQQLPSEEVLKRLEHARAYNQTLEPHKLQDPYTEEEKAGVVEYARMLEV
                     KEKIGFVEIPKINERIPIYAGTTEEVLQKGAGHLEGSSLPVGGESTHTVITAHRGLPN
                     ASLFTNLDHLKVGDQFYIHNIAEVLAYEVDQILVVEPNNFDPVIVQNGKDYATLLTCT
                     PYMINSHRLLVRGHRVPYEPKVAIKQKPAFFLDMLTLSYLVALLIIVVIVIILYLLRR
                     KKYQKGEMK"
     gene            4755..5579
                     /locus_tag="AC1PIV_000256"
     CDS             4755..5579
                     /locus_tag="AC1PIV_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HIP6611312.1"
                     /translation="MMKRIGYVFILVGLLLPLVLLTNMSVQEFQVFQQYQYYRRNSKF
                     FSTEQLEEIKAYGEQVSGGDLPTVDPFAEKNDSNSTDVLSSELMEGAIGYLSIPKIEI
                     RQPIYVGATSEHLNDGVASVIGTALPIGGIGRRSVIAGHRSWYNDLRFFRLSELREGD
                     KIFIEVGGRTLTYLVKNTEVIKATDWQKLLPVESQDMVTLLTCDPLVPPFDYRLLVNA
                     YRESDVIEEADEVSQTSQREIKQFQQYSFSLVFYLTIFGWVLLLYILYRFIRTYIW"
     gene            complement(6101..8542)
                     /gene="sntA"
                     /locus_tag="AC1PIV_000257"
     CDS             complement(6101..8542)
                     /gene="sntA"
                     /locus_tag="AC1PIV_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme-binding protein SntA"
                     /protein_id="HIP6611313.1"
                     /translation="MNFRFSKCAVALTLALLAASNPKLAQAEEILNTTPASSTEASQA
                     VPVESDTTEEADNTESPVPATTEAENPSSSETAETSDPTSETTDTTTSEARTVTPAAT
                     ETSQPVEGQTVDVRILATTDLHTNLVNYDYYQDKPVETLGLAKTAVLIEEAKKENPNV
                     VLVDNGDTIQGTPLGNYKSIVDPIEEGEQHPMYAALETLGFDVGTLGNHEFNYGLAYL
                     EKVIRTANMPLVNANVLDPTTKDFLYTPYTIVKKTFTDTEGKKVTLNVGVTGIVPPQI
                     LNWDKAYLEGKVIVRDAVEAVRDIIPTMRENGADIVLVLSHSGIGDDQYEVGEENVGY
                     QIASLSGVDAVITGHSHAEFPGTAEKPSFYAKYSGVDDTNGKINGTPVTMAGKYGDHL
                     GVIDLNLVFKDGKWTTTSSKAAIRKIDTKSSVADGRIIDLAKEAHNETIKYVRQQVGE
                     TTAPINSFFALVQDDPSVQIVNNAQIWYAKQQLAGTSEANLPILSAAAPFKAGTRGDA
                     SAYTDIPAGPIAIKNVADLYLYDNVVAILKVNGAQLKEWLEMSAGQFNQVDLSSTEPQ
                     NLVNTDFRTYNFDVIDGVTYQYDITQPNKYDRDGKIVNETASRVRNLQYNGQDVTADQ
                     EFIVVTNNYRANGTFPGVREASINRLLNLENRQAIINYIIAEKVINPTADNNWTFTDS
                     IKGLDLRFLTADRAKSLVTDQECIVYLQASTASEGFGEFKFVYTESKVVTPDEQQSDQ
                     GNTGQDIVLESGQRITLPAVNPPAPAPQHKLASPHSQASTKTLPATGEATSMLSLLGL
                     TLIGFVGAWTKKKEH"
     gene            8798..10999
                     /locus_tag="AC1PIV_000258"
     CDS             8798..10999
                     /locus_tag="AC1PIV_000258"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008728 - GTP diphosphokinase activity
                     [Evidence IEA];
                     GO_function: GO:0008893 - guanosine-3',5'-bis(diphosphate)
                     3'-diphosphatase activity [Evidence IEA];
                     GO_process: GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RelA/SpoT family protein"
                     /protein_id="HIP6611314.1"
                     /translation="MKEINYTGEEVVALTATYLPEEDVIFVKKALDFATEAHKSQFRK
                     SGEPYIVHPIQVAGILAGLKLDAVTVACGFLHDVVEDTDVTLDDMEAEFGPEVRHIVG
                     GVTKLGKVEYKSHEEQLAENHRNMLIAMSQDMRVILVKLADRLHNMRTLKHLRKDKQE
                     RISRETMEIYAPLAHRLGISSIKWELEDMSFRYLNEIEFYKITRMMSEKRREREELVN
                     EVVEKLRDYTEERHLHGQIYGRPKHIYSIYRKMHDKKKRFDQLYDLIAIRCIMDTPSD
                     VYAMLGYIHELWKPMPGRFKDYIANQKANGYQSIHTTVYGPRGPIEFQIRTMEMHQVA
                     EYGVAAHWAYKRGGKATASEKELRWINNLIELQEGAGDAQTFVNSVKDDIFTERIYVF
                     TPDGAVRELPKDSVPIDFAYEIHTKVGERATGAKVNGRMVPLTTKLKTGDQVEIITSA
                     NSFGPSRDWVNLVKTHKARNKIKQFFKNQDKELSVSKGREMLQNLLQENGYVPNQYLD
                     RRHMDEVLQKTSYKTDESLFAAVGFREVSAISIFNRLTEKERREAERAKAKAVADELV
                     NGGEVKHDNKDSLKIRHEGGVVIEGASGLLIRIAKCCNPVPGDEIVGYITKGRGVAVH
                     RVDCMNLKSQENYDVRLIDVDWEDENSTKEYMANIDIYGLNRSGLLNDVLKVLTNASK
                     NISSVNAQPTKDMKFATIHVSFGISNLATLTSLVDKIKSVPEVYSVKRTNG"
     gene            11001..11444
                     /gene="dtd"
                     /locus_tag="AC1PIV_000259"
     CDS             11001..11444
                     /gene="dtd"
                     /locus_tag="AC1PIV_000259"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - peptidyl-tRNA hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HIP6611315.1"
                     /translation="MKIVLQRVSQASVTIEGSIHGQIEQGLLLLVGVGPDDSQEDLDY
                     AVRKIVNMRIFSDEAGKMNKSVQDVAGKILSISQFTLFADTKKGNRPAFTGAAAPALA
                     SQLYDAFNQALSAFVPVEVGVFGADMAVSLVNDGPVTIVLDTKNK"
     gene            11520..11705
                     /locus_tag="AC1PIV_000260"
     CDS             11520..11705
                     /locus_tag="AC1PIV_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611316.1"
                     /translation="MKKLLTNHFFYLTIAFLLILVIYFSGIDKRWIILASFLYFIPSQ
                     ILYRRRLRERLQEDQPK"
     gene            11860..12000
                     /locus_tag="AC1PIV_000261"
     CDS             11860..12000
                     /locus_tag="AC1PIV_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HIP6611317.1"
                     /translation="MSTFEVLTLMFVAGNFVIALVMLVLELVKTTKKITVYNFGEFTV
                     IF"
     gene            12178..12809
                     /locus_tag="AC1PIV_000262"
                     /pseudo
     CDS             12178..12809
                     /locus_tag="AC1PIV_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018164076.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
     gene            12789..12998
                     /locus_tag="AC1PIV_000263"
     CDS             12789..12998
                     /locus_tag="AC1PIV_000263"
                     /EC_number="3.4.26.-"
                     /inference="COORDINATES: protein motif:HMM:NF014566.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family glutamic-type intramembrane
                     protease"
                     /protein_id="HIP6611318.1"
                     /translation="MNPLNISVLITAVLFAFVHSYEISLSFWSALFPGFLFSWIYYKT
                     NHLKYPIVAHILSNSIVTILNVISV"
     gene            13062..13736
                     /locus_tag="AC1PIV_000264"
     CDS             13062..13736
                     /locus_tag="AC1PIV_000264"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamic
                     endopeptidase"
                     /protein_id="HIP6611319.1"
                     /translation="MKIIKSIVLAVGTLLLTLLIQFPAYVGITAFQENVLLKLAVMIG
                     LGLPILALLSVIRRGMMKHQVFSREKLNVLKIVGMTALVFTGQTCLNLFWQYLGLSLS
                     DSNAMDTVNQLNSDNFGVMALSVVLFAPVLEEFLYRGILLEKTAQYFPKHPQMVIVFS
                     ALLFAYCHTWNFSVAFLGHFITGAYLGYLYMCNRRMTDTILAHSFYNASILFLQILFG
                     LVQIGG"
     gene            13834..14109
                     /locus_tag="AC1PIV_000265"
     CDS             13834..14109
                     /locus_tag="AC1PIV_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611320.1"
                     /translation="MRKFFQDLNQEYLETRSSVGEDWLEWIIQRKMTWGMRWGLVGIL
                     MFVLQPLTYNPHFLLGCFYIGFLLWLVYVCGQLFFAARSIFRNLKKR"
     gene            complement(14145..14804)
                     /locus_tag="AC1PIV_000266"
     CDS             complement(14145..14804)
                     /locus_tag="AC1PIV_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HIP6611321.1"
                     /translation="MTPNKEDYLKCIYELGQLDQKITNKLIAEKMAFSAPAVSEMLKK
                     MVAEELISKDAKAGYLLSQTALEMVASLYRKHRLIEVFLVEQLGYSPEEVHEEAEILE
                     HTVSDHFINRLDLLLEQPQTCPHGGSIPQAGQPLIERYQTRLSQLTETGNYQLVRIHD
                     FYQLLQYLEQHELAVGDLLTVTAFDQFAQTITIQYKDKELAVPTAIAQQLFIEKSNRP
                     A"
     gene            14930..15853
                     /locus_tag="AC1PIV_000267"
     CDS             14930..15853
                     /locus_tag="AC1PIV_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter solute-binding protein,
                     Zn/Mn family"
                     /protein_id="HIP6611322.1"
                     /translation="MKKILFSFALLLSLIGLGACRPSQTTEGSSKPRVAVTTSFLNDM
                     VYQLAGDEVERDLLIPAGEDPHLYVAKSSDLSKLQKADLVLYHGLHFEGKMVEALEKT
                     GVAVSKNFNAKDLNTMDEDGEEIVDPHFWFSIPLYKSAVAVASEELQKLLPAKAEMIQ
                     KNTEKYQAQLDDLHAWVEKELSVIPKESRYLVTPHDAFNYFAASYDFTLYAPQGVSTD
                     SEVANSDMIETVNLIIDHNIKAIFTESTTNPERMKKLQEAVKAKGGQVEVVTGEGKEL
                     FSDSLAPEGEEGDTFIDMYKHNVKLMVKYLK"
     gene            16407..17177
                     /locus_tag="AC1PIV_000268"
     CDS             16407..17177
                     /locus_tag="AC1PIV_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HIP6611323.1"
                     /translation="MSAIIELKDVNLAYTASQTMALEDVNLVIPRGSRTAIVGPNGAG
                     KSSLFKVILGLEKPDTGQVRLLGQEAGLERLIAQKVAYIPQSSQVNWQFPATVFEIVL
                     MGRFAHSKGMFRRPTKADRQIVEQALERLKIADLRHRQIDQLSGGQRQRVFLARALAQ
                     EAELYLMDEPLAGIDQATEIMIMDMLKEFQCEGKTSIVIHHDLTTLDAYFDHLVWLHK
                     HVIDSGPMDETLTSENYQATYGIGNGLFLGNAKGGSHV"
     gene            17170..18030
                     /locus_tag="AC1PIV_000269"
     CDS             17170..18030
                     /locus_tag="AC1PIV_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HIP6611324.1"
                     /translation="MFEVFKEYSFWTVALGTVSLAVAASTIGSISVLTKQSLLGDALG
                     HASYPGVIVSFMIFQSRHPLYLLLGAVLSGYLSYALVHWLRRKGGHSLVNALSLVSAS
                     FFGLGMVLKNAIQGNEAFAGASQAGLQTYLFGQAAFIQLDDVILIGIISLLALALFAF
                     FYQDYKLYLFDQTFARVIGVRVKYLQQLTMFLMICLIAVGLKLVGAILMSSFLIAPAV
                     FGLMLGKSYHKSLLLAGIVAIGSAFVGTWISSSVSGLSTGPTIIVCLTGLTLSAFVYI
                     TYVRKENGRV"
     gene            18023..18862
                     /locus_tag="AC1PIV_000270"
     CDS             18023..18862
                     /locus_tag="AC1PIV_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HIP6611325.1"
                     /translation="MFEVLLILMVIASSCGLLGSILVVKNQSMLADALSHSVLLGIVL
                     GFFISHSLDSPLLIVGASLFGLLSVLAIDRLHSRKIAHDAATGLVFSFFFAVAVLLIS
                     LFARNVHLDVDLVLQGEVLFAPLHRMDVLAWSLPVSLVKSSLAWLVIVLFFAWAYHRL
                     QVYLFDSNHARLSGLRTRILEMVILILVSLTTVLAFEAIGSMTVIVFLVAPSMAALCW
                     VKSFWQLLLLGQGIAILTVVLGFLVANQLDLTMSGTCAVVSLLVVCSSIILKNTWSRS
                     SDK"
     gene            18918..20810
                     /locus_tag="AC1PIV_000271"
     CDS             18918..20810
                     /locus_tag="AC1PIV_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloendopeptidase"
                     /protein_id="HIP6611326.1"
                     /translation="MIRLQDDFYEYVNGEWAKTAVIPDDKPRTGGFTDLADEIEKLMI
                     DTTNAWLAGEDVPEDSVLQNFVAFHKQVADYEIRDRLGAEPAQALIAEYKALNSFEEF
                     TSKLAEYELAGKPNLMPFGVAPDFMDATTNVLWADSLGIILPDTTYYEEGHEKGAELL
                     KTWRESQEALLPKFGFSDEEIKDLLDKRLELDATIAKYVLSNEEGSEYAKLYHPYEWA
                     DFTALAPELPLDDFFTAILGQTPDKIIVPEERFWQAAKDIYCADNWELLKATLILKAA
                     GAYTAFLSDEIRILAGAYSRALSGTPQAQNQEKAAYNLAQGYFNQALGLWYAGEKFSP
                     EAKADVEAKVAKMIEVYKSRLETADWLAQETRDKAIVKLNVIKPYIGYPEALPERYYK
                     KLVDPSKSLVENAIELNKIDIAHGWSKWNKPVDIKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDSNGASFDEHGSLNNWWTEEDYAA
                     FEARTQQVIDQFEGQDSYGAKINGKLTVSENIADLGGIAAALEAAKSEDDFSAEEFFT
                     NFARIWRMKARPEFMQMLASVDVHAPGHLRTNIQLPNFDEFHETFGVQEGDGMWRAKE
                     DRVIIW"
     gene            20913..23414
                     /gene="leuS"
                     /locus_tag="AC1PIV_000272"
     CDS             20913..23414
                     /gene="leuS"
                     /locus_tag="AC1PIV_000272"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HIP6611327.1"
                     /translation="MSFYNHKEIEPKWQEFWAKNHTFKTGTDAEKPNFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPADFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLEEVDWPESIKD
                     MQRNWIGKSTGANVTFKIKDTDKDFTVFTTRPDTLFGATYAVLAPEHDLVDSITSAEQ
                     AEAVAEYKRQASLKSDLARTDLAKDKTGVWTGAYAINPVNGKEIPIWIADYVLASYGT
                     GAIMAVPAHDERDWEFAKQFGLDIIPVLEGGNVEEAPYTEDGAHINSDFLDGLNKEEA
                     IAKMVAWLEENGVGQEKISYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPENELPLV
                     LPKTSDIKPSGTGESPLANLTDWLEVVREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NDEKLADEDLLKAWLPVDIYIGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDSRGALVATDKVEKRDGSFFHMETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQFGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLLTTKELVAENSGALD
                     KVYNETVKTVTEHIEDLKFNTAIAQLMIFVNAANKEDKLYVDYAKGFVQLIAPFAPHL
                     AEELWQGLANTGQSISYVAWPTYDESKLVESEVEIVVQIKGKVKARLTVAKDLAPAEL
                     EKVALADEKVQAEIAGQTVVKVISVPNKLVNIVVK"
     gene            23589..24950
                     /locus_tag="AC1PIV_000273"
     CDS             23589..24950
                     /locus_tag="AC1PIV_000273"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008706 - 6-phospho-beta-glucosidase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HIP6611328.1"
                     /translation="MLKTLKLVTIGGGSSYTPELVEGMILRAHQLPIREWWFVDVEQG
                     AKKQEIVVELARRMVAKAGLDWKIESTLDRREALIEADFVTSQFRVGQLPARYLDETI
                     PLSYGMLGQETNGAGGIFKAFRTIEAYKGIIKDMKDLCPNAWLINFTNPAGIVTEAIA
                     NELHWKKVIGLCNIPIGQKKLAAQILGQSEGDLSTRHIGLNHFHFHEVWDKYGENRTQ
                     VILETLYGDLREEMPEAVKNITNLEFPIQLLRTIGMLPCDYHRYYFLEQEMLEDALEQ
                     YRQGNVRAKVVQEVETELFELYKDPQLKDKPKQLELRGGAYYSDVACQIICAIHNDSR
                     EELTVSTVNRGVIPYLPENCVVEVTSIISAQGATPLACPPTPPIVTGYLQLMKQMELV
                     TVQAAMTGDYSLALQAFTLNPLISNGPQAEVLLQDMLLAHENYLPQFAPAIQHIKERR
                     NNQ"
     gene            24947..26347
                     /locus_tag="AC1PIV_000274"
     CDS             24947..26347
                     /locus_tag="AC1PIV_000274"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HIP6611329.1"
                     /translation="MTKDKVFYQFPTNFLWGSSTSGPQSEGIEPGDGKGQNNWDYWYS
                     IEPERFHNKIGPSQTSTFYKHYEKDIDLLVETGHTVFRTSIQWSRLIPTGTGEINQEA
                     VSFYRSVFSLVRAKGIQLFVNLYHFDLPYCLQEKGGWENKEIVRAYEAYARTCFELFD
                     DLVDRWITFNEPIVPVECGYLGNYHYPCKVDAKAAVAVAYHTQLASSLAVKACHEVNP
                     HKKIAIVLNLTPAYPRSEQAEDIKAARIAELFQTKSFLDPSVLGEYPDDLVELIDAYG
                     LMPEVSDEELAIIKENRVDFLGVNYYQPLRVQAPTNSWKEGEPLTPEYFFAPYDMPGK
                     KMNPHRGWEIYEKGIYDIAINIKENYHNIEWFVTENGMGVEGERAFKDNGLIQDDYRI
                     EFIEDHLIELHRAIQEGANCKGYMLWTFIDCWSWLNAYKNRYGLVELDLDTQERIVKK
                     SGKWFKKLSDANGFHR"
     gene            26357..27463
                     /locus_tag="AC1PIV_000275"
     CDS             26357..27463
                     /locus_tag="AC1PIV_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HIP6611330.1"
                     /translation="MVELGFSIYPENYSLEESQAYIKLLHQYGARRLFMSLLQLENGD
                     RTVFELYQKLIDYANQLGMTVIADISPHFIAAQGWDGALMERAAELGLAGIRLDEALP
                     LEEIIEMTHNPRNIKVELNLSTDKILLSNLLASVANRDNIIACHNFYPHAFTGLSEEH
                     FLEMSSFYHQSGIRTAAFVSAQTASEGPWPLSEGLPTLEDHRFWPLPLQIAWMKATGF
                     IDSILISNQFISEEELQSIQTVLNEDTISLMVDIEEGLTPVEREIVAFNHVYRGDISA
                     YVLRSTMPRVVYKDASVPARSDQAIPVGRGDILIDNDLYGRYKGELQIALKEFTISPK
                     VNKVGRISPDYLPLLRFIKPWQEFKLVIASEHFH"
     gene            27555..29549
                     /locus_tag="AC1PIV_000276"
     CDS             27555..29549
                     /locus_tag="AC1PIV_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HIP6611331.1"
                     /translation="MLSKKEVRLLEALLAKQETFVPSIELAKVLSVSDRTVRTYIHQL
                     TSSLENSGAHILSKQGSGYCLQIERPVEFEMFWQEQLLLKKRLTDLTQLEEAGDRQRY
                     ILNKLLFEDPIQSPDCLQRELFIGKTTLHSILADIRKLFIPYQLELLVTRKGIELKGD
                     EPAIRHFIMDYFFDEGNVQSVYGVVETNLLPDIRFTDLMLIVLDECRDAKLRLSDFVM
                     QNLVLHIALLLQRLKIGSGLDRFPIPERIQSSQEYLVAQRIIDRIEETFQVTIPSEEA
                     NYIALHLKVKLTGNPNQDGEVEEIFRQNVENSLLHLSHLTGLELSKDQQLFKGVLAHL
                     MPLRIRLENNIQLGNPLTAEIKDQYFEAFELTKMAFAAIPELMGYSISDDEWAYLTLH
                     VMAAIERYQGFKKTRVLVVCATGIGSALMLKNRLEKEFSSSLEILDTVSYYEVTEERL
                     KDVDLIISSISLSNLIFMTPVINVSVFLSEKDIEAIRSHLQQTTPVIPDQGENVLMEV
                     GQAKQIAEAVFAPHRIIYLEEDCDREVALKQLVTSLDESIEPDFVNRFIEQVNLRESY
                     SPVVFGNRLAFPHPALPMSYSEQIVVGIYKNAVDWGHGKQVQFVFLLSPSKGRNAFLK
                     YISPCLVDFVQDRVLQERLLHHPNYKELIDIFIPLIQRKG"
     gene            29562..29873
                     /locus_tag="AC1PIV_000277"
     CDS             29562..29873
                     /locus_tag="AC1PIV_000277"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HIP6611332.1"
                     /translation="MKHIMLVCNAGMSTSMLVTKMQKAAEETGVEATIWAVPVSEADN
                     EVAQKEIDVLLLGPQVKFLLNDYKAKFEPTIKVDAINMMDYGVMNGAKVLEAALKMME
                     G"
     gene            29875..30189
                     /locus_tag="AC1PIV_000278"
     CDS             29875..30189
                     /locus_tag="AC1PIV_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HIP6611333.1"
                     /translation="MNSPEYLEAIMGLIMYGGEAKGFASQAIQAAKEGRIDEAEQLLQ
                     DAIASLNIAHKSQTQLLAKEASGESVELSLLMVHGQDHLMNALTFIDLAKEFVDLYKQ
                     IG"
     gene            30208..30648
                     /locus_tag="AC1PIV_000279"
     CDS             30208..30648
                     /locus_tag="AC1PIV_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HIP6611334.1"
                     /translation="MKISKIGQVPIERLFATIRQSLKDDFQQNTGSILQDQDIIQGLT
                     YTKTFGDKGQHSVKVTVEEFTAPYCYAVCFHSNRGKEHVRYQLEDLGNDQTNIEYSYE
                     MEAGDIFVKGNQFLMEKIFSKSIKRQTNAQLEALIRCSVEPVSV"
     gene            30692..32068
                     /locus_tag="AC1PIV_000280"
     CDS             30692..32068
                     /locus_tag="AC1PIV_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HIP6611335.1"
                     /translation="MSNISEKFMEISGKIGSQRHLIAIRDSFISMMPITMAGTVAVLL
                     NVFLRDIPNNMGWTGFADAMQPVIDINGYVYFGTIGIMALVFAFTFGYNLSLMYKVNP
                     LAGGLISFASFISTIPQSVTISTALDGVDKSVVSALEGLGLSIVTTDGVSALETSQWG
                     AIALKYGGATGLFTALFIGFLATWVYASLVKRNVIIKLPDSVPPAVNKAFAAIIPGTA
                     AIYASSIVAYLAFTLTGQSLGDLVSTYIQLPLLGLSQGLGSVILLTFLVQLFWFFGLH
                     GHNVLAPIMDGVYMVALNENAAAYTATHSTANLPWLWTRGSFDAYAQMGGSGVTLALI
                     IAIFIFSKREEYKMVAKLSAPMGVFNINEPVTFGIPMVLNPLFAIPWLIVPPICATIA
                     YLATAAGIIPPVFAPVPWITPPGLYAYLATGGNIMAALVSLFNLFVAFLIWTPFVIAA
                     NKVKAGEE"
     gene            32400..33011
                     /locus_tag="AC1PIV_000281"
     CDS             32400..33011
                     /locus_tag="AC1PIV_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA];
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HIP6611336.1"
                     /translation="MSYQMIKKQFKLGLFTALIGNLLWLGMVNVSADDTVISDSPTVS
                     ALTKKVEAAKIAAKAAAEKIVAEKAAAAAKAALATNMVSEVALEYTANTYPAGQCTWG
                     AKEMAPWVGNYWGNGGDWAASAAALGYEVGTTPKVGAIAVWTDGGYGHVAYVTDVAAN
                     GHIQVKESNYGGVYYPSNVRGFFDPTTTSEGTVSYIYPPAGVN"
     gene            33174..33962
                     /locus_tag="AC1PIV_000282"
     CDS             33174..33962
                     /locus_tag="AC1PIV_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HIP6611337.1"
                     /translation="MFTSLLFAGIVLAACNSSAGTSNSTDQTLLAQIKEEGVIQIGTE
                     GAYAPYSYHDESGKLVGYDVEVAEAVAEKLGVKVEFVETEWDSMIAGLDAARFDTIAN
                     QVGITDERKAKYDFSTPYTYIYGALVTQKDNTDITSFADLSGKKSANSLTSNWADLAR
                     ENGAEVVGVDGFSQAVELLNTGRVDATINDNLVYLDYVKQHADAPIKVVTLTDDVSTT
                     AFPVAKGNEDLVKEIDAALAELASEGKLAEISNKYFGEDVSKAK"
     gene            33975..34634
                     /locus_tag="AC1PIV_000283"
     CDS             33975..34634
                     /locus_tag="AC1PIV_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HIP6611338.1"
                     /translation="MTERVWQLLLDSFSQILVPGLLVTIPLTILSFTFGLLIAIGTAL
                     VQIAQIPILKQVARFYIWVVRGTPLLVQLYVIFFGLPSLGIVLDAFPSAVLVFSVNTG
                     AYAAETIRASIESVPKGQLEAGYSVGMSFAQTMRRIILPQAFRVAFPPLSNTLIGLVK
                     DTSLAANITVLEMFMATQQIAARTYEPFALYCEVALVYLFFSTILTKLQAYGEKKLAV
                     Y"
     gene            34644..35390
                     /locus_tag="AC1PIV_000284"
     CDS             34644..35390
                     /locus_tag="AC1PIV_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015424 - ABC-type amino acid transporter
                     activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HIP6611339.1"
                     /translation="MIQANGVKLTFGGQQVLKGIDVEVNPGEVVVILGPSGSGKTTLL
                     RSLNFLEKADAGHLVFGEDSYDLAQMTKKEIAGIRKRTAFVFQNYNLFANKTALQNVT
                     EGLIVARKVPKQEAERIGKAALDKVGLSDKYGFYPSQLSGGQQQRVGIARAIATNPEV
                     IYFDEPTSALDPELIGEVLAVMMQLAKEGMTMVVVTHEMGFARAVADRVIFMDGGRII
                     EEGRPEDIFDQPKEERTKQFLARIQKVDVE"
     gene            35756..36697
                     /locus_tag="AC1PIV_000285"
     CDS             35756..36697
                     /locus_tag="AC1PIV_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HIP6611340.1"
                     /translation="MTTLADVARLANVSKMTVSRVINHPEQVTQELRTLVTAAMEELN
                     YKPNVAAKALAQQRTLIVQAVILEKMDVVEPYYIDLLAGIADELNHRNYTLQLVTNPS
                     QITDQCDGYIVTGARKDDYPWLKGLRKPLILFGENQEGLPFVDSDNRLATRSATQFAL
                     SKGYERIVFVGIDLPEAFEKGREEGYKDAMQGRETHLYRLENRSRVAEEFVKNLDYLP
                     ENTCFICASDRLALGVTRGLQALGKSIPNDVGVIGFDGFFLDRMSRPALTTMKQPIRQ
                     MGALSVKHLMTILDGKPLARQGHYCQATLIERETTPQ"
     gene            36879..43187
                     /locus_tag="AC1PIV_000286"
     CDS             36879..43187
                     /locus_tag="AC1PIV_000286"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014917327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pullulanase"
                     /protein_id="HIP6611341.1"
                     /translation="MKKKSVQNMKRTGMLEKKQIFGIRKLNVGVASVGIAAALFLSGA
                     GQLVQAEEVVLPASTSSTTLSEQDGGAVEATTTAIEATDSMVAEATAVTETADATAPE
                     EAPIEEGSIRLHFENVDETAPESQGLWTWGGVAEPSDGNQWPTDTANFSSSQVDDYGH
                     YVDIKKSETPGTIGYLVLKNGEKITESDQKVELLVPEQNEAWIASDYSVSSYEPLKDE
                     NVLRINYTREDNNYEGWGVWTWGDTTEASSGWPAGAVDFKLGKYGAYVDIPLSNGLDS
                     KLGFLLINQNNPDLAGNKTIDLAFADRKRHSQIFLRNDDDKVYTNPYFIEEKVELDTS
                     KATPGTKNVTVGASVKAPFNYNESGLVSVTVTNPENAEIVKMEVDTSAIGGGLVPIST
                     ELNRVTIKATSSTAPGTYSLPVKVYDKDNGYYETKLDVTITERIKADGEKDWDEQVIY
                     FMMTDRFYNGDTGNDKLVEGTASNPRGLYQGGDFKGVTAKLDYLKELGVDSIWLTPIV
                     ENIPQNVGSVKDGEYYAYHGYWASNFEKLNPHLGSLADFHELIDAAAEKGINIIVDVV
                     LNHAGYGTEETFAGMVRTKEEDKQGDDQLGSLSGLPDFKTEEAAVRNQLVAWQASWLE
                     RSTTAKGNSIYAFRVDTVKHVDDTTWQHFKNELVDRDPDFHLIGETWGANYKDTKGDL
                     GIGTMDSLLDFGFKDIAKYLVNGQLKAAGKELEERSKVLTSAASLGQFLGSHDEDGFL
                     YSLGGAEKEGNLDKLKLAASLLITAKGQPVIYYGEEVGQSGQNNWPVYDNRYDFDWSK
                     VETSDITDHYQKLLAFRNANSTLLSRGDTSTLAGNDSQGWLISKRSYQDQAAYLVFST
                     NTENKEMALEVSGKDVVVTDAYTGKSYQAIEKDGKWVVQVELPTIGQGGTMLLQTEAG
                     DIVNASVQGATEEPIEAGYFRVHFKTLPSDNLSSLGLWTWDDVEKPSSDLGAWPTGAT
                     NFSTAKQDDYGYYLDIKMKDETASKISLLINNTSGDNITGDKTIERISTKMNEAWFDE
                     NYQLSLYQPLKEGYIRINYFRTDGNYDQKGLWIWGDVTDLTLGDWPNGIDFENQGKYG
                     AYIDVKLTDLPSSIGFLLLDESKSGDDVKIQQKDYSFKDLKNQTQIFLKDDDATIYTN
                     PYFVNNVRATGVSHVSLTALEAAFTTLEGADKDSILEKLSVTDKNGQTVAVTDLVLDL
                     TSNKVRVLGDFNQENAGYTLKYGNDSFTTTMSWQLKDELYAYDGELGARVRQAGSVVD
                     MTLWSPSADSVAVVLYDKDDQSKVVGKLAMTKGDKGQWDLELNSQSGLGIADYRGYYY
                     HYEITRGDQSVLVLDPYAKSLAEWNSDLADTDPSYRIAKAAIVDPAEVGPSDLNYATI
                     PNFNQREDAIIYEAHVRDFTADPAISDELTAQFGTFAAFAERLSYLKELGVTHIQLLP
                     VMSYYFVNELKNAERMSEYASSNSNYNWGYDPQSYFAFTGMYSTDPTDPMKRIEEFKN
                     LVNEIHKQGMGVILDVVYNHTSKTFLFEDLEPNYYHFMEADGTAKSSFGGGRLGTTHY
                     MSRRVLVDSIKYLVDEFKVDGFRFDMMGDHDAEAIELAFTEAQKLNPNIIMLGEGWRT
                     FTGDANQPVQPADQDWMSSTDTVAVFSDEIRNTLKSGYPNEGQPAFITGGAKSVESVF
                     NNIKAQPGNFLADDPGDVIQYIAAHDNLTLFDIIAQSIKKDPSVTENYTEIHQRQRLG
                     NLLVLTAQGTPFIHSGQEYGRTKQFRHPDYKEPVTEDKVPNKAHLLTNADGTPFDYPY
                     YIHDSYDSSDAVNKFDWTKATDEALYPENTRTQAFTKGLIALRKSTDAFRLGTKEEVE
                     QKVSLISIPGQNGIAKNDVVIAYQTIASNGDRYAVFVNADSKERSFVLSDIYKELLKG
                     QVLVDGERAGVEALSDLVGVELTDSSVVLAPLTATVIRLPYITTALPDTAPTAEEKPS
                     LDFTTKERTEETVLPIAEEVRYDATLAKGQSYVLQEGKAGKRVLVYQDVLVDGKVVAT
                     NLLSETVVDGEARIVVKGSMEAKDVVEKPSLSTPTAQASGQATSGASKASLPITGDRQ
                     SDLALLGLGLAGLGLTVAAQGRTKKSEE"
     gene            43515..44963
                     /locus_tag="AC1PIV_000287"
     CDS             43515..44963
                     /locus_tag="AC1PIV_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HIP6611342.1"
                     /translation="MDFLQTPLNWFSQNILQNPAFFVGLLVLVGYALLKKKPHDVFAG
                     FIKATVGYMILNVAAGGLVTTFRPILAALNYKFQIDAAVIDPYFGLAAANGKIAEEFP
                     DFVSAATTALLIGFGVNILLVALRKVTKVRTLFITGHIMVQQAATVSLMVLFLIPALR
                     NQFGTAAIGIICGIYWAVSSNMTVEPTQRLIGGGGFAIGHQQQFAIWFVDKIAPKLGK
                     KEENLDNLKLPSFLNIFHDTVVASATLMLVFFGVILFILGPEIMANPEVITSGAPYNP
                     AKQAFFMYVIQTAFTFSVYLFILMQGVRMFVAELTNAFQGISSKLLPGSFPAVDVAAS
                     YGFGSSNAVLSGFAFGLIGQLITIVLLIVFKSPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAAILSFISGVLQVALGAVCVGLLELSGGYHGNIDFEVPWLPFGFAFKYLGIAGY
                     VLVCLFLLAIPQLQFAKAKDKEAYYRGEAQAE"
BASE COUNT        13078 a         8393 c        10521 g        13063 t
ORIGIN      
        1 attaaacact tagtccatgc cgaagatacg gctagcacaa ccgttattgt tcacaaaatc
       61 gtaatgaata atgacgattt caataaattt acttatgaag aaaatttatc caaatataat
      121 ggtaattcaa tcggagattt gaagaattat tttggtaatt ctgccgtgga agttgcggga
      181 gtaaaatttg acgtatggaa aaagacagat gtagtagctc cagaagctaa gacaggtgca
      241 gaacttggta ttactggaga tacaaataag tatgtaaaaa ccgataaaac tgcaatgaca
      301 caagataacg gtgcaacatt cactctagct aatggcattt atatcttcac tgaagataaa
      361 gaaaattcac cttactacaa taatcagaat gaacttactg gtatgaaagc tgtaccattc
      421 aagcttgaat tgccacaggc taaaacagat ggttctggat actttgatac caaaactcct
      481 cttcatgtgt atccaaagaa tactgaaaac aaacctgaaa tcaccaaaga attcactgat
      541 aagagaacaa atgttgatca agatggtata aaaaatgttg aaatcggtca ggaaattggt
      601 tacactatta caacaaaagt ccctaaggac gcagcatata agacatttgc ttgggaagat
      661 accatgcttg caggtcttga tttcaaacta aactcactac aaatcgcaga taataaaaat
      721 cttaaccttt gtagcagata cagactacac attgacacaa actgtacgtg gattcatggt
      781 gaaattgaat aataacggtc ttgcgaaatt agaagaaaaa gcaagagaag gtgaagtgaa
      841 ctttaccttg acttacaagg ctactttaaa tgactcagcg aaagtagaga ctgaaatccc
      901 taaccaagta aaattgattt acggtaaccg tccaagtgaa ttctctgagc caaaatcaac
      961 aactccaaaa gatggtgaaa ttattgttaa caaaacatgg gatactggtg taaaccaaac
     1021 agaagttgta ttcggtgtat atgaaaaagg aactggtgta cgtgtaggtg aaattaaact
     1081 tgcagcaggt gttaatactg gaaaattaac tggtcttgat ggtgctaaag aatacatcgt
     1141 aattgaagaa acaatcgttt caggctcact tcctagctat tcaaatggtg atacaggtac
     1201 tatcagaata gaaaacaaga aaaatccaaa tccaactccg ctcacaccag aagatccaaa
     1261 agttgtcaca tacggtaaac gatttgtgaa gacagatgat aaggatttgg acagtagcga
     1321 aaaacttcta ggtgctgagt tcatcgttcg taaagatggt gaagagtcat atcttgcttt
     1381 gaaagataca gtaacacaag caaaagaaat cgcagattat aaagcagcgg aagctgatta
     1441 tttagctact gttaaatcag ccacaacaga caatcctaaa attgatgaaa ttaagcagaa
     1501 gaaagatgct cgcgacactg cttacgaaaa gatgaacatg caatggactt gggtaggtac
     1561 taaggaaggt gcgtttacat ttgtatcatc aacagatggt aagtttgaag tcaaaggtct
     1621 taaagaaggt aagtatgaac ttattgaaac caaggctcca gaaggattcg ctctccctac
     1681 ttcgcctgtg gaattcactg taggagcaca tacatggggt acaatagatg cattgacagc
     1741 agataacttc caacaaatca aaaacaaaaa agtaaccatt ccacaaacgg gtggtatcgg
     1801 tacacttgtt ttcacaattg taggtttgag tactatggta tttgccttta tcgcgatgaa
     1861 aaagcgtcaa tctgaagaag cttaattatt actagaaagg aggggcagat gaaaacagta
     1921 agacaaataa tatgttgcct tgtcgctata atatgtgtat tatcattgcc ctcgctttca
     1981 ctccaagcac aagattcttt tgatgttcag gttcatattc ctttccctaa tggaatagat
     2041 gccagtcaag tttcgacggg tttggaggct tggtacatcg cttcagaaga acccgtttct
     2101 tctgaacagt tggcagattc tttatatcaa aaaagtcggt ctgagttgac cagtctctat
     2161 ggtgagccaa tttcttctca agctctttct ccagaaggtc aagccacttt tcgaggattg
     2221 actaagggat ggtattatgt tcggcaagta ggaaagccta cgagtctaga agttatccca
     2281 ttcttgatga atgtaggtag aggtgttaca aagattgagg ctaaggtcag gagacctagc
     2341 gaagaaaagg gtagcaagcc atttttaaag gtatcaacca gcaccgcccc tttatctggg
     2401 gcagaatttg cggttcttga ggaagtaggc ggagaattga aggaagtgat agtcgacggc
     2461 aattcttatc acgtcacgtc aagttcgaat ggtcagtttg tggtaggtcc tcttccttat
     2521 ggtacttact acttaaaaga ggtcaaggcc cctactggct acattttatc tcaagatacg
     2581 attccttttg aaataacctc ggattcacat gtgtccgaga ttattaagat taagaataaa
     2641 cctgttacac ctcctggaat tgaaattcca tatacaggaa atgtggtggt gattgcagtt
     2701 ttatctaccg gtattttgct cttcttgcta ggttatcgct tggtaactta tactaagcga
     2761 taacgtttga cagactagaa tagagggaaa atcccattgt caggttgaat ctggggcaat
     2821 gggatttttc gttttaaagt tggattatgg tataataaaa gcagaatgta ggggatttta
     2881 tactcttcga aaatcaaaat tatccgttgt caactagcct tgatgaactc cagttctgtc
     2941 ttcggcttcg tttctcaggc tacttttggt ttttcattga gtattaactt tgcaatgcag
     3001 tagaaagaca atggaagaat aatgaagttc ggattatgat acagaaaaaa tcgggaaaaa
     3061 ctacaaagaa aaaaaagaaa agtaatatcc ccttttactt ggtatttttg attggatttg
     3121 ggattttact ttatcctcat gtttctaatt tttattatcg atatgagtcg gatcagctga
     3181 ctaattcttt cgaccaagaa aagaagacct tagcttctga ggaggttaag gaacgaatag
     3241 atttggctca agcttttaat gagagtttga acaatgtggt ttcggaggat ccgtatacca
     3301 aatcacgaca tgaagctgga cgggtagagt atgcacggat gctggaattg catgaaaaga
     3361 taggttatgt tgaaattcca aaaattgagg tcaagcttcc tgtttatgca ggaacttctg
     3421 agaccgttct tcaaaaaggt gtagggcatt tggaaggaac atccttaccg attgggggga
     3481 gcgataccca tactgtctta acggctcata caggtttacc caaagctcgg ttattcacag
     3541 acttaacgaa ggtaaaaatc ggtgatactt tctacattca caatatcgta gaaacattag
     3601 cgtatgaagt agatcaaata gtggttgctg aaccaactca atttgaggaa ttgctggtca
     3661 agcctgggca ggactatgca accttgctaa cctgtacgcc ttacatggtg aatacgcacc
     3721 gtttattggt acgcggtcat cgtattcctt atgttgcaga agagcatctt aaagcgtctg
     3781 aaaatgcaga gaagcgtatt cttattcgtt atcttcttta tgcgctcgga atgtttgtcg
     3841 gtattttact gattttctta ttaacaaaaa ggcggaaaaa taaaaagaaa gtgacgagta
     3901 atgatgaaac gttcacaact tagaaaggga atatctaaac agtccatact cttgaagctt
     3961 ttatttctct ttggtttagt agtgacgcta tatccgtgga tttctcaata ttattatcgt
     4021 tatgactctg attataaaat ccaatcattt tatgaacaag cacaacagtt accgagtgaa
     4081 gaagttctga aaaggttgga gcatgctagg gcctacaacc agaccttgga acctcacaaa
     4141 ttgcaagatc cttacacaga agaagagaag gctggggtag tggaatacgc tcgtatgctt
     4201 gaggtgaagg agaaaattgg ttttgtagaa attccgaaaa tcaacgagag aattcctata
     4261 tacgctggga caactgagga agtattacaa aaaggagcgg ggcatttgga aggttcctcc
     4321 ttgccagttg gtggagaaag tactcatact gtgattacgg cgcatcgtgg tcttcctaat
     4381 gcttcgctat ttaccaatct cgatcattta aaagtcgggg atcaattcta cattcataat
     4441 atagctgagg tattggctta tgaggtggac cagattttag ttgttgaacc gaataatttt
     4501 gatcctgtta tagttcaaaa cggaaaagac tatgcaacct tgctaacctg tactccttat
     4561 atgattaaca gccatcgttt gttggtacgt ggacatcgcg ttccttatga accgaaagtt
     4621 gcaatcaagc aaaaaccggc attctttttg gatatgctaa cgctatccta cttggtagcc
     4681 ctattaatca tagtagtgat tgttattatc ctctatcttc tccgtaggaa gaagtatcaa
     4741 aagggggaaa tgaaatgatg aaaagaatag gatatgtttt catattggtt ggtttgttgc
     4801 ttcctttagt gttgctgaca aatatgtcag tgcaggagtt tcaagttttc caacagtatc
     4861 agtattatcg taggaattct aaattctttt cgacagagca actcgaagaa attaaggctt
     4921 atggggaaca ggttagtggt ggtgacttac ccacagttga tccctttgca gaaaaaaatg
     4981 attcaaatag taccgatgtg ttatcttctg aattaatgga aggggcaatt ggttatttga
     5041 gtattccaaa aattgaaatt cgacaaccta tttatgttgg ggcaaccagt gaacatttaa
     5101 atgatggagt tgcttctgtt ataggaacag ctttacctat aggtggaata ggtcgacgaa
     5161 gtgtcattgc cggtcaccgt agttggtaca atgatctcag atttttccga ctgtcagagt
     5221 tgagagaagg cgataagatt tttattgagg ttggtgggag gacgctgacg tatttggtaa
     5281 aaaatacaga agtgataaaa gcaacagatt ggcaaaagtt attacctgtt gagagtcagg
     5341 atatggtaac cttgttgaca tgtgatccac tagttcctcc ttttgattat cgcttgttag
     5401 tcaacgctta tcgcgaatca gatgtaatag aggaagctga tgaagtgagt cagaccagtc
     5461 aacgtgaaat aaagcagttt cagcaatatt cattcagtct tgtattttac ctgacgatat
     5521 ttggttgggt cttgttgctt tatatccttt accgttttat tagaacctat atttggtagg
     5581 atgaagggtg tttttggcgt atgcagaggt caaaagaggg ttgaaacaaa gataggcttc
     5641 ctcctagtga gcatgaattt atacttttcg aaaatcaaaa gcagacattg ttaacttgat
     5701 ttgatgaact tcggttctat ctgcatctgc gtcgcctagt ctgattttta ttttcattga
     5761 gtattaacga aaattggtta agaaattagt ccaaaacaat gggagcaaaa gaaaaacaca
     5821 gacagcttag ctggatttca tcaaaatcag cttgagtcta tctgtgtttt tttattgagt
     5881 gcaaaagggt attggtatag tgacaagtcg tacgaacgcc tctttatact cttcgaaaaa
     5941 caaaattatc cgttgtcaac ttaccttgat gaactccagt tctatcttcg acttcgtttc
     6001 ctaggctact tttgattttc attgagtatt aagaggttcg tgacgagtca aaagcaatga
     6061 ggcttgaaca agggctagtt tttgctcagt ctcgtctatt ttaatgttct tttttcttag
     6121 tccatgcgcc gacaaaacca atcaaagtga gaccgagcag actaagcata gaagtagctt
     6181 ctcctgttgc agggagtgtc ttggtgctcg cttgtgaatg tggactagcc aatttatgtt
     6241 gtggagcagg agcaggtgga tttaccgctg gaagagtaat tcgttgacca gattcgagta
     6301 caatatcttg acctgtgtta ccttgatctg actgctgttc atctggagtc actactttag
     6361 attcagtgta gacaaatttg aattcgccaa atccttcgct ggcagttgaa gcctgtaggt
     6421 agacaataca ttcttggtca gtaactagag atttcgcacg gtctgctgtc aagaagcgga
     6481 ggtcgagtcc cttgatacta tctgtaaagg tccagttatt gtctgctgta ggattgataa
     6541 ctttctcagc gataatataa ttgatgatgg cttggcggtt ttccaggttc aacaatcggt
     6601 tgatagaagc ttcgcggacc ccagggaaag taccgtttgc acggtagttg ttggtcacca
     6661 cgatgaattc ttgatcagct gtcacatctt gcccattgta ttgcagattc cgaactctgc
     6721 tggcagtttc gttgactatc ttaccatcac gatcgtattt atttggttgc gtaatatcgt
     6781 actgataagt tactccgtca ataacgtcaa aattgtaagt gcggaaatct gtgttgacta
     6841 ggttttgtgg ctctgttgag cttaggtcaa cttggttgaa ttgccctgcg gacatttcca
     6901 accattcttt gagttgggca ccgttgactt ttaagatggc tacaacgttg tcgtagaggt
     6961 aaaggtctgc tacgttcttg atggcgattg ggccagcagg aatgtctgta taggctgaag
     7021 catcgcctcg agtaccagcc ttaaatggtg cagccgcaga taggattggt agattagctt
     7081 ctgaagtacc cgccaactgt tgttttgcat accaaatctg tgcattgtta acaatctgta
     7141 cagatggatc atcttgaaca agggcaaaga agctgttgat tggagcagtt gtttcaccga
     7201 cttgttgacg aacatatttg atggtttcgt tatgggcttc tttagcaagg tcgatgatgc
     7261 gaccatctgc tacagatgat tttgtatcga ttttacgaat agccgctttg ctagaagtag
     7321 ttgtccattt gccatcttta aagaccagat tgaggtcgat gacgccgagg tgatcaccgt
     7381 atttacccgc catggtgaca ggagtaccgt tgattttacc atttgtatca tctacgccag
     7441 agtatttagc atagaagctt ggtttttcgg cagttcctgg gaattctgcg tgggagtgac
     7501 ctgtgataac cgcatcaact cctgacaggc tggcgatttg gtaaccgaca ttttcttcgc
     7561 cgacttcata ttggtcatcg ccgatacctg agtgggaaag gaccagaacg atgtctgcgc
     7621 cattttctcg catggttggg ataatatcgc gaacggcttc aactgcatca cgaacaatca
     7681 cttttccttc tagataagct ttgtcccagt tgagaatttg agggggaaca atccctgtaa
     7741 caccgacatt tagtgtaacc tttttaccct cggtgtctgt gaatgtcttt ttcacaatgg
     7801 tataaggggt gtagagaaag tctttcgtag tcggatcgag gacattggcg ttgactagag
     7861 gcatgttggc tgtacgaatt actttttcga ggtaggcaag gccgtagtta aattcgtggt
     7921 tgccaagtgt gccgacgtca aatcccagag tctctaaggc ggcgtacata ggatgttgtt
     7981 caccttcttc aataggatca acgatagact tgtaatttcc aagaggagta ccttgaatgg
     8041 tgtctccatt atctaccaat acgacatttg gattttcttt ttttgcttct tcgataagaa
     8101 cagctgtttt tgctagaccc agtgtctcta caggtttatc ttggtaatag tcatagttga
     8161 ccaagttcgt atggaggtca gttgttgcga gaatgcgaac atcaacagtt tgtccttcaa
     8221 caggctgact agtttcagtt gcagcaggag tgaccgtgcg tgcttctgaa gtagttgtgt
     8281 cagttgtctc gcttgtagga tcactagttt cagctgtctc ggaagagctt ggattttcag
     8341 cttcggtagt ggctggaacc ggagattctg tattatcagc ttcctctgtg gtgtcagatt
     8401 caactggtac agcctgactt gcttctgttg aagaagctgg agttgtgttg agaatctctt
     8461 cggcttgagc taattttgga ttgcttgcag ctaagagagc tagtgtgagt gctacggcac
     8521 acttactgaa acgaaaattc ataagaatcc tccattttct ttttgtaata atcttctaca
     8581 atcattatac agctaagaaa tgcaaaattc aagactaatt ctgaacgttc gtttgaaaaa
     8641 cgagtgaaaa taacaagaaa acgaaagaaa acaagaacgt tcaccgaatc tgaacttggt
     8701 ttggattgtt tgtaattagt agtcttatgt tagattcctt tttctttttt cgtgaaaatg
     8761 gtagaatagt aggaaatata agaggaagag tagagatatg aaagaaatta actacactgg
     8821 ggaggaagtg gttgctttga cagccaccta tttaccggaa gaagatgtta tatttgtcaa
     8881 gaaagctttg gattttgcga cagaggcaca caagtcacaa tttcgtaaat cgggcgagcc
     8941 ctatattgta cacccgatcc aggtagcagg tattttagca ggactcaagc tggatgctgt
     9001 gacggttgcc tgtggtttct tacatgatgt ggttgaagat acggatgtaa ctttggatga
     9061 tatggaggct gaatttggtc cagaggttcg ccatattgtc ggcggtgtga ccaaactggg
     9121 taaggttgag tataagtctc atgaggagca gttggctgaa aaccaccgaa atatgctgat
     9181 agccatgtcc caagacatgc gggtcattct ggttaaactg gcagaccgcc ttcacaacat
     9241 gcggactctt aagcacttgc gcaaggacaa gcaggaacgt atttcacgtg aaacaatgga
     9301 aatctatgca ccgcttgccc accgtctagg tatttcttct atcaagtggg aattggaaga
     9361 catgtctttc cgctatctca atgaaattga attctacaag attactcgaa tgatgagtga
     9421 gaagcgtcgt gaacgggaag agttggtcaa tgaagttgtt gagaagctaa gagattatac
     9481 agaagagcgc catctacatg gtcagattta cggtagaccc aagcatattt actctatcta
     9541 tcgcaaaatg cacgataaga aaaagcggtt tgatcaacta tatgacttga ttgccattcg
     9601 ttgtatcatg gatactccga gcgatgtcta tgctatgtta gggtatattc atgaattgtg
     9661 gaaacctatg ccaggtcgct tcaaggacta cattgccaac caaaaagcta acggctacca
     9721 gtctattcat accacggttt acggaccgag aggtccaatc gagttccaaa ttcggaccat
     9781 ggaaatgcac caggttgcag agtacggggt tgcggctcac tgggcctaca agcgtggtgg
     9841 caaggcaact gctagtgaaa aagagttgcg ctggattaac aacctgattg aactccaaga
     9901 aggggctggg gatgcgcaaa cctttgtaaa ttctgtcaag gacgatattt ttacagagcg
     9961 tatttacgtt ttcacgccag atggtgcagt gcgtgagttg cctaaggact ccgtaccgat
    10021 tgacttcgcc tatgagattc ataccaaggt cggcgagcgg gcgacaggtg ccaaggtcaa
    10081 cggccgtatg gtgcctctga cgaccaagct caagacaggc gatcaggtgg aaatcatcac
    10141 ctctgccaac tctttcggtc caagtcgtga ctgggtcaac ttggttaaaa ctcacaaggc
    10201 tcgcaataaa atcaagcagt tcttcaagaa tcaggacaag gaattgtctg tttcaaaagg
    10261 gcgtgagatg cttcagaacc tactccaaga aaatggctac gttcccaacc aatacctgga
    10321 ccgtcgccac atggatgagg tcctgcaaaa gaccagctat aagaccgacg aatccctttt
    10381 tgcggcagtt ggttttagag aagtttctgc catatcaatc tttaaccgtc tgacagagaa
    10441 agaacgtcgc gaagctgagc gggctaaggc caaagctgtc gcggatgaat tggtcaacgg
    10501 tggcgaagtc aaacacgaca acaaagatag tctgaaaatc cgtcacgaag gtggcgtggt
    10561 cattgaagga gcgtcaggct tgctgatacg gattgccaaa tgttgtaacc cagtacctgg
    10621 cgatgaaatt gtcggctaca tcaccaaggg gcgtggggta gcggtccacc gtgtggactg
    10681 tatgaacctc aagagtcaag aaaactacga tgttcgcttg attgatgtgg actgggagga
    10741 tgagaattcg accaaggaat acatggcaaa cattgacatt tacggtctca accgctcagg
    10801 tcttctcaac gatgtcctca aggttttgac caatgccagc aagaatattt cgtcagtcaa
    10861 tgcccagcca accaaggata tgaagtttgc gaccatccac gtttcctttg gcatttctaa
    10921 cctggcaacc ttgaccagtc tggtggacaa gatcaagtcg gtgccagaag tttactcagt
    10981 gaaaaggacc aacggataag atgaaaattg tattacaacg tgtatcacag gctagtgtga
    11041 ccatcgaagg aagtatccat gggcaaattg aacaagggct tttgctccta gtcggtgtgg
    11101 ggccagatga cagccaggaa gacctggact atgctgttcg taaaattgtc aatatgcgga
    11161 ttttttcaga tgaggcaggc aagatgaaca agtctgttca agatgtggcg ggcaagattt
    11221 tatccatttc ccaatttacg ctttttgcgg atacaaaaaa aggcaatcgc cctgccttta
    11281 caggagcggc agctcctgcc ctagccagcc aactctatga tgcttttaac caggccttgt
    11341 cagcctttgt gcctgttgaa gtgggcgttt ttggggcgga tatggcggtt agcctggtca
    11401 atgatgggcc ggtgaccatt gttttggata cgaaaaataa gtaaaacttt tggcaatggt
    11461 atgtactcta tttgtgtatt ttgatatact aatattgaaa aataggtatg gaggatgcta
    11521 tgaaaaaatt gctcacaaat catttctttt atttgacgat tgcctttctt ttgattttgg
    11581 tgatttactt tagtggaata gataaacgtt ggattatttt ggcaagtttt ctttacttca
    11641 ttccatcgca gattttatac cgtcgtcgcc taagagagcg actccaagaa gaccagccca
    11701 agtaggctgg ttttttgatg tgtaaattgg actacaattc tttattaact gtgctataat
    11761 agtttttgca gaaaagtaaa gacggtggct ctaatttctg aaaggtaggt ggtgtctatg
    11821 ggcaaatcat caaaatctaa cagaaaggag aagctatctt tgtcaacctt tgaggtctta
    11881 acactcatgt ttgtagctgg taactttgtt atcgctctcg tgatgttagt acttgaattg
    11941 gtgaaaacga caaaaaaaat aaccgtctat aactttggcg agttcacggt tattttttaa
    12001 taatttataa caagccaccg tcttaaacgg ttctgcaagg ggtagttgtt tccagcaact
    12061 accttttcct atgtttatta tacattggca ggtctaccaa gtcaagttgg acacttatct
    12121 tttgtctaaa tatgctataa taatgattat aacttacaaa aagtttagga gatagcaatg
    12181 cttaatattt ttgtattaga agatgatttt tttcagcaga gcaggttaga aaatgctatt
    12241 aggcagtgtg ttgaagaaac gtcagtaagg tataaattcc tagaagtttt tggtaaacca
    12301 aatcaattat tggaatcaat tgaggaagca gggaatcatc aatttttctt tttagatatt
    12361 gaaataaaag gagaagaaaa gaaaggaatg gaaatcgcta aagaaatccg ggctcgagat
    12421 ccttatgctg ttattgtctt tgtaacaact cactcagaat ttatgccagt aacatatcgt
    12481 tatcaggttt ctgctttaga ttttatagat aaaggcctgg aggatagtga ctttcaaaag
    12541 gcagtatcag atgtcttagt gcatgctttt gaaaatattg atcatactgt agctgaaaat
    12601 tcttttgtat acaaaactga aactgctcat attcaagttc cttttagtga catcctttat
    12661 tttgaaaatc atcaacgatt cataaagtca ttttaaaaac gaaaacaggt cagacagagt
    12721 tttacgggaa agtatcggat atagcgaaag ctgatgaaag actttaccag gcacatcgtt
    12781 cttgtgtagt gaatccatta aatattagcg tgttaattac agcagtttta tttgcttttg
    12841 tacatagtta tgaaatttct ttgagtttct ggtcggcact ttttccagga tttttgtttt
    12901 cttggattta ctataaaacg aaccatctca aatatccgat agtggcacat atcttgtcga
    12961 acagtattgt gaccatttta aatgttataa gtgtttaaag gtgtgaacat tgtgaaaaac
    13021 aattgagtag gttataaatg acaatggaaa ggagagagaa tatgaaaata ataaaatcca
    13081 tcgttttagc agtgggtacc ttgctgctca ctttgctcat tcaatttcca gcttatgtgg
    13141 ggataacagc ctttcaagag aatgtgctac taaaacttgc agtcatgata gggcttggtc
    13201 ttccaatatt ggcactactt tctgtcatca gacgaggaat gatgaagcat caagtctttt
    13261 caagagagaa gctgaatgtt ttaaaaatag tcggaatgac agcactggta tttactggac
    13321 aaacttgcct gaacctcttt tggcagtatt tgggtcttag ccttagtgat tctaacgcca
    13381 tggatacagt caatcagtta aattcggaca attttggggt gatggctctc tcagttgtct
    13441 tgtttgctcc agttttagaa gaatttcttt acagaggaat tttgttagaa aagacagccc
    13501 agtattttcc taagcatcct caaatggtca tcgtattttc tgcccttcta tttgcttatt
    13561 gtcatacctg gaacttttca gtggcatttt taggtcactt tatcacaggg gcttatctgg
    13621 gctatctgta tatgtgcaat agacgaatga cggatactat ccttgcacat agcttctata
    13681 atgcctccat tttattcctc caaattttat ttggtttggt gcagattggt ggataaaaat
    13741 tgacagtaga cattttgtgg aaatgcctgt atactgagag gaagttggca attttataat
    13801 tgctaactat caagtgcaga ggtgggcaga aatatgagaa aattttttca agaccttaat
    13861 caagagtatc tggaaaccag aagttcagtt ggagaagatt ggctggagtg gattatccag
    13921 agaaagatga cctggggtat gcggtggggg ttggtaggga ttctcatgtt tgtcttgcag
    13981 cctttaacct ataaccctca ttttctattg ggctgttttt atataggttt cctactttgg
    14041 ttggtgtatg tatgtgggca actatttttt gcagccagat ctattttccg taatttgaaa
    14101 aagaggtaac tatttatttt agaagaaaaa atcgctcagc ttgtttaggc tgggcgattg
    14161 cttttttcga tgaataattg ttgagcgatg gctgttggga cggcgagctc tttgtccttg
    14221 tactggatgg tgatggtctg ggcaaactgg tcgaaggctg tgacggttag taaatcaccg
    14281 acagctaatt catgttgttc caagtactga aggagttgat agaagtcatg gatacggaca
    14341 agctggtagt tccctgtctc agttagctgt gacagccgtg tctggtagcg ttcgatgagc
    14401 ggttgtcctg cttgaggaat gcttcccccg tgaggacaag tttgaggctg ttccagtagc
    14461 aggtctaggc gattgataaa gtgatctgaa acggtgtgtt ctaaaatctc agcctcttca
    14521 tgtacttctt ctggagagta gccaagttgc tcaactaaga atacctcaat caagcggtgt
    14581 ttgcgataga ggctggctac catttcaagg gcagtttgac tgaggagata acctgccttg
    14641 gcatccttag aaatgagctc ttcggctacc atttttttga gcatttcgga aacggctggt
    14701 gcggagaagg ccatcttctc tgcgatgagt ttattggtaa ttttttggtc taattgaccc
    14761 agttcataaa tacattttag gtaatcttct ttgtttggtg tcatgagaac tcgctttctt
    14821 ctgaaactat tatatcaaaa aatttaaaaa tcagttgaca aaatgatttt tttagattaa
    14881 tctaattata tagttaggta tgcttaataa aaataaaagg agaacctata tgaagaaaat
    14941 attgttcagt tttgctctgc tattgtccct aatagggtta ggagcttgtc gtccatcgca
    15001 aaccacagaa ggctctagta agccaagagt ggctgtgact acttccttcc tcaatgacat
    15061 ggtctatcag ttggcgggtg atgaggtgga acgtgatttg ctgattccag caggagaaga
    15121 ccctcatttg tatgtagcca aatctagtga tttatcaaaa ttacaaaagg ctgaccttgt
    15181 tctctatcac ggtttgcact ttgaaggtaa aatggttgaa gctttggaga agaccggagt
    15241 agctgtttct aaaaacttta atgcaaaaga cttgaatacg atggatgagg atggagaaga
    15301 gattgtcgat ccgcacttct ggttttcaat tcccttgtac aagtcagctg tagctgtagc
    15361 ttcagaggaa ctacaaaaac tcttacctgc taaagctgag atgattcaga aaaatacaga
    15421 aaaataccaa gcgcagctag atgatttgca tgcctgggta gaaaaagaat taagtgtgat
    15481 tccaaaagaa agtcgctatt tggtaacacc acatgatgcc tttaattact ttgctgctag
    15541 ttatgacttc actctttatg ctcctcaagg cgtgagcacc gactcagaag tggctaacag
    15601 tgacatgatt gagacagtta acctaatcat cgaccataat atcaaggcta tctttacaga
    15661 gtctacaacc aatccagaac gcatgaagaa attgcaagag gcagtaaaag ccaaaggtgg
    15721 tcaggttgaa gttgttactg gcgaaggtaa agagttgttc tcagattcct tggcaccaga
    15781 aggcgaggaa ggggatacct ttatcgacat gtacaaacat aatgttaaac tgatggttaa
    15841 atatctgaaa tagtacaggt cgaacggact tgctattcaa tgaagactag agatattacc
    15901 aaagatagag ttgataggta ccaatatgag ggacaatcaa ttgtttcgag cacaagcggt
    15961 atagggctct ttctattgga ggtggtaacg cttgggggag gataggcgtt agtagcaaat
    16021 cacaccagtt attgaggtcc ttgactagaa ataccgcttg tagacctcga tgatcttggt
    16081 ttacagcggg actttatata tcagtagtct gtgcgtgaat agagatttca aatgagtagt
    16141 aaaaaggact cggtctaggt cgagttcttt ccgtttttgg accattttta acagatttat
    16201 aaacatacga ttgaaggaag cattggtgct ctgcgaaaat caaattcatg tactgatgtg
    16261 ttgaaataag cgatgtatag ggtttgccag caatttgttg gtacggtatc ttaatcttat
    16321 cgactttctc agcttggtag gttggtctgg ttttgatttt cattgagtat gaatgaggca
    16381 tatcattttt aaaaatagga ggaaatatgt cagcaatcat tgaattaaaa gatgtcaatt
    16441 tagcatatac agccagccag accatggctt tagaagatgt caatttggtg attcccagag
    16501 ggagtcggac ggctattgtt ggaccaaatg gtgctgggaa gtccagtcta ttcaaggtca
    16561 ttttggggtt ggaaaaacct gacacagggc aggttcgctt gcttggtcag gaggcaggtc
    16621 tagagaggtt gattgctcaa aaagtagcct atattcccca atccagtcaa gtaaattggc
    16681 aatttcctgc aacagtcttt gaaattgttc tgatgggacg cttcgctcat agtaagggaa
    16741 tgtttagaag accgactaag gctgatagac agattgttga gcaggctcta gaacggttaa
    16801 aaattgcgga tttacgccat cgtcagattg atcagctttc aggtgggcag cgtcagcggg
    16861 tatttttagc gagagccctg gcacaggaag cagaattgta tcttatggat gagcctctag
    16921 cagggattga tcaggcaaca gaaatcatga tcatggatat gctcaaggag ttccaatgtg
    16981 aagggaaaac ttccattgtc attcatcatg acttaacgac gctggatgcc tactttgatc
    17041 accttgtctg gcttcataag catgtgattg actctggtcc gatggatgag actttgacaa
    17101 gcgagaatta tcaggcgacc tacggcatag gaaatgggtt gtttctagga aatgccaaag
    17161 gaggcagtca tgtttgaggt tttcaaagag tattctttct ggacagttgc tttagggacc
    17221 gtcagcctag ctgtagcagc cagcactatc ggaagtatat ctgttcttac taaacagagt
    17281 ttgcttgggg atgctcttgg gcatgcttct tatcctggag tgattgtctc tttcatgatt
    17341 tttcagtcgc gacatcctct ctacttgctg ttaggagcag tgttgtcagg ttacctttct
    17401 tatgcacttg tccattggct gcgtcgaaaa ggaggtcaca gcctagtcaa tgccctttca
    17461 ttggtgtctg cttctttctt tggtttggga atggtcttga aaaatgctat tcagggaaat
    17521 gaagcctttg caggggcttc ccaggctgga ttgcaaacct atctatttgg acaggcagcc
    17581 tttattcagc tggatgatgt gatactcatc ggaattattt ctctattggc tttggcattg
    17641 tttgctttct tttatcaaga ctataagcta tatctgtttg atcaaacttt tgcaagggtt
    17701 attggtgttc gtgtaaagta cttgcagcag ttgacgatgt ttttgatgat ttgcctaatt
    17761 gcagtaggat taaagttagt cggagctatt ttgatgagta gttttttgat tgcaccagct
    17821 gtctttggct tgatgctggg aaaatcgtat cacaagagtc tattactggc aggaatcgtt
    17881 gcaattgggt cggctttcgt agggacctgg attagctcca gtgtatctgg tttgtcgacc
    17941 ggaccgacta ttatcgtctg tctgacaggt ctgaccctgt ctgcatttgt gtatattacc
    18001 tatgtcagaa aggagaatgg tcgtgtttga agtattactc attttgatgg ttattgctag
    18061 ttcttgtggc ttgctcggct cgatactggt tgtaaaaaat caatcaatgc tggcagatgc
    18121 gctatcgcat tctgttttgc ttgggattgt tctgggattt tttattagtc atagtttgga
    18181 ttcgccattg ctaatagttg gtgccagtct gtttgggtta ttatcggttc ttgccattga
    18241 ccgtctgcat agtcgaaaga tagcgcatga tgccgcaaca ggtctagttt tttctttctt
    18301 ttttgcggtg gcggttttac ttatttctct ttttgctcgc aatgttcact tggatgtgga
    18361 tctggttttg cagggggaag tactttttgc tccgctccat cgtatggatg ttctagcctg
    18421 gtcactccct gttagtctgg tcaagtcgag tttggcttgg ttggttattg ttctattttt
    18481 tgcgtgggct taccatcgtt tacaagtgta cctatttgac agcaaccatg ctcgtttgtc
    18541 tggcttacga acaaggattt tagaaatggt tattttgatt ctagtttcct taactactgt
    18601 tctggccttt gaagcgattg gttcgatgac tgttattgtt ttcttggtgg caccaagtat
    18661 ggctgcccta tgttgggtca aatccttttg gcaattgctt cttttagggc aaggtatcgc
    18721 tattctaacg gttgtgctag gttttttagt ggccaatcaa ctggatttaa ccatgtcagg
    18781 gacctgtgcc gttgtcagcc ttcttgtggt ttgttcgagt attattctaa aaaatacttg
    18841 gtcacggtca tctgataagt gaaattgtca gaattttttg ttattatagt cattaagaaa
    18901 gacaaaggag aaaatcaatg atacgtttac aagatgattt ttacgaatac gtcaatggtg
    18961 aatgggcaaa aacagccgtg attccagatg ataagccaag aacaggtggt ttcacggact
    19021 tggcggatga gattgaaaag ctcatgattg acacgacaaa cgcttggttg gcgggagaag
    19081 atgtcccaga agatagcgtt ttgcaaaact ttgtggcttt tcacaaacaa gtagctgact
    19141 atgaaatccg tgaccgtttg ggtgcagaac ctgcccaggc cttgattgca gagtacaagg
    19201 ctctcaactc tttcgaagaa tttaccagca agctggcaga atatgagttg gcaggcaagc
    19261 caaacctcat gcctttcggt gtggcacctg actttatgga cgcgaccacc aatgtcctct
    19321 gggcagattc tctaggcatt atcctgccag atacgaccta ctatgaagaa gggcatgaaa
    19381 aaggagcaga gttgctcaaa acgtggagag agagccaaga agccctctta cctaagtttg
    19441 gtttcagtga tgaggaaatc aaggacctct tggacaagcg tttggaacta gatgccacga
    19501 ttgccaagta tgttctgtca aatgaagagg gttctgagta tgcaaaactc tatcacccct
    19561 acgagtgggc agattttact gccttggcac cagagttgcc tttggatgat ttcttcacag
    19621 cgattttagg tcaaacgcca gacaagatta tcgtgcctga ggaacgtttc tggcaggctg
    19681 caaaggacat ttactgtgcg gataattggg agcttttgaa ggcgaccttg atcttgaaag
    19741 cggcaggagc ttatacagcc ttcctgtcgg atgaaatccg tattctagca ggagcctaca
    19801 gccgtgctct ttctggtaca ccgcaggcgc aaaaccaaga aaaagcagcc tacaacttgg
    19861 cacaaggcta ctttaaccaa gccctcggtc tttggtatgc aggagaaaaa ttctcaccag
    19921 aagccaaggc cgatgtggaa gccaaagttg ccaagatgat tgaggtttac aaatctcgtt
    19981 tggaaacggc agactggttg gctcaggaaa cgcgtgacaa ggccattgtc aaactcaatg
    20041 ttatcaagcc ttatatcggt tacccagaag ccttgccaga gcgttattat aagaagcttg
    20101 ttgacccaag caagtccttg gtggaaaatg ccatcgaact aaacaagatt gacattgctc
    20161 atggttggag caagtggaac aagcctgtgg acattaagga atggggcatg ccagctcaca
    20221 tggtcaacgc ctactacaat ccacagaaga acttgattgt cttcccagcg gccattttgc
    20281 aggcgccttt ctactctctg gagcagtctt catcagctaa ctacggcggt atcggtgcgg
    20341 ttattgccca cgagatttct catgcctttg actcaaacgg tgcttccttt gatgagcatg
    20401 gtagccttaa taactggtgg acagaggaag actatgctgc ctttgaagct cgtactcagc
    20461 aggtcatcga ccagtttgag ggtcaggatt cttacggtgc caaaatcaat ggtaaattga
    20521 ccgtgtcaga aaacattgcc gaccttggtg ggattgcggc agccctagaa gcagccaagt
    20581 cagaagatga cttctccgca gaggaattct tcactaactt tgctcgcatc tggcgaatga
    20641 aggctcgtcc tgagttcatg cagatgttgg ctagtgtcga tgtccatgca ccaggtcacc
    20701 tacgcaccaa catccagttg ccaaacttcg atgaattcca tgaaacattt ggcgttcaag
    20761 aaggcgacgg catgtggcgt gccaaagaag accgtgtgat tatttggtaa aaatgggaaa
    20821 acagctagtg aaaactggct gtttttgtct ttcccaattc ccccaaaacg tgatataata
    20881 gtaaagataa tttattgaca tggagaaatg acatgagctt ctataatcac aaggaaatcg
    20941 agcccaaatg gcaagaattt tgggcaaaaa atcatacttt taagacagga acagatgcag
    21001 aaaagccaaa cttttatgcc ctagatatgt tcccttatcc gtctggtgcg ggcttgcacg
    21061 ttggtcaccc tgagggctat acggcgacgg acattctcag ccgttacaag cgtgcccaag
    21121 gttacaacgt tcttcaccca atgggttggg atgcctttgg tctgccagct gagcaatacg
    21181 ctatggatac aggcaatgac ccagctgact ttacggcgga aaatattgcc aacttcaaac
    21241 gtcagattaa cgcccttggc ttttcttacg actgggaccg cgaggttaat acgactgacc
    21301 ctaactacta caagtggact cagtggattt tcaccaaatt gtatgaaaaa ggcctagcct
    21361 atgaggcaga agtgcctgta aactgggtag aagaattggg aacagctatc gccaacgaag
    21421 aggtccttcc tgacggaacg tctgaacgtg gtggttatcc agttgtccgc aagccaatgc
    21481 gccaatggat gttgaaaata acggcctatg cagagcgttt gcttaatgac ttagaagaag
    21541 ttgattggcc agagtctatc aaggatatgc aacgcaactg gattggcaag tctacgggtg
    21601 ccaatgtgac tttcaagatt aaggacacag ataaggactt cacagtcttt actacccgtc
    21661 ctgacaccct tttcggtgcg acctacgcag tccttgcccc tgagcatgac ttggtagata
    21721 gtatcacatc agctgaacaa gcagaagctg tggcagaata caaacgccaa gcctctctca
    21781 aatcagacct ggctcgtact gacctggcta aagacaagac cggtgtctgg acaggtgctt
    21841 atgccatcaa ccctgtcaac ggtaaagaaa ttccaatctg gattgccgac tatgtactgg
    21901 caagctacgg aacaggtgct atcatggccg ttcctgctca tgacgagcgt gactgggaat
    21961 ttgccaaaca gtttggtttg gacattattc cagttctgga aggtggcaat gtagaagaag
    22021 ctccttacac agaggacggt gcccacatca attctgattt cctagatggt cttaacaagg
    22081 aagaagctat tgccaaaatg gtagcttggt tggaagaaaa cggtgtcggt caggagaaga
    22141 tttcttaccg cctccgcgac tggctcttca gccgccagcg ttattggggt gagccaattc
    22201 caatcatcca ctgggaagat ggaacttcca cagccgtacc agaaaatgag ttacctttgg
    22261 tattgccaaa aacctcagac atcaagcctt caggtacagg ggagtcacct cttgctaact
    22321 tgacagactg gttggaagtg gtgcgtgaag acggtgttaa aggtcgccgt gaaaccaaca
    22381 ctatgccaca atgggcgggt tctagctggt actacctccg ctatatcgac ccgcacaatg
    22441 atgagaaatt ggcagacgag gatcttctca aagcttggtt gccagtggac atctacatcg
    22501 gtggtgctga gcacgcagtc cttcacctgc tctacgctcg cttctggcac aagttccttt
    22561 acgaccttgg cgttgtgccg accaaagagc cattccaaaa actctttaac caagggatga
    22621 ttttgggaac tagctaccgc gacagccgtg gtgcccttgt agcgacagat aaagttgaaa
    22681 aacgcgatgg gtccttcttc cacatggaaa ctggtgaaga gttggagcag gcacctgcta
    22741 agatgtctaa gtctcttaaa aacgtggtta acccagatga tgtggtcgag caattcggtg
    22801 cggacactct ccgtgtttat gaaatgttca tgggtccact tgatgcgtca atcgcttggt
    22861 cagaagaagg tctcgaaggc agccgtaagt tccttgaccg tgtctatcgc ctcttaacca
    22921 ctaaggagct tgtggcggaa aatagcggag cgcttgataa agtttacaat gaaactgtga
    22981 agacggtgac agagcatatt gaagacctga aattcaacac agctatcgcc cagctcatga
    23041 tttttgtcaa cgcagccaac aaggaagaca agctttatgt tgactacgcc aaaggttttg
    23101 tccaattgat cgccccattt gcaccacact tggcagaaga actctggcag ggtcttgcaa
    23161 atacaggcca gtcaatcagc tatgtcgcat ggccaacata tgacgaaagc aagctggtag
    23221 aaagcgaagt ggaaatcgtt gtccaaatca aaggcaaggt aaaagctcgc ttgaccgtag
    23281 ccaaagactt agcaccagct gaacttgaaa aagttgccct tgcagatgaa aaagtccaag
    23341 ctgaaatagc tggtcaaaca gtggtgaagg tgattagtgt tccgaataaa ctagttaata
    23401 ttgttgtgaa ataaatgtaa ataataagaa aacgacttcc gtattggagg tcgtttttgt
    23461 attttctaga atgatcatgt tgtcttaatt tccgttgtga tacggaaaaa gagggtctgt
    23521 gtatccgttt acaatagatg ttcactgaaa tataataaga atataaaaga agatgaggga
    23581 gggaaagcgt gttgaaaact cttaaattag tgacaattgg tggaggctca agttacactc
    23641 cagaattggt tgaaggtatg attcttcgtg cacatcaatt acccattcga gaatggtggt
    23701 ttgttgatgt tgaacaaggc gcaaaaaaac aggagatcgt agttgagtta gcacggcgaa
    23761 tggtcgcaaa agcaggcctg gactggaaga tagagtcgac cttagacaga agagaagcat
    23821 tgatagaggc tgattttgta acgtctcagt tccgagttgg ccaactacct gcaagatact
    23881 tagatgagac cattcccttg agttatggga tgctggggca agagaccaat ggggctggag
    23941 gaatctttaa agcatttagg accattgaag catataaagg gattatcaag gatatgaagg
    24001 acttgtgtcc gaatgcttgg ttgattaatt ttacgaatcc tgctggtatc gtaacggaag
    24061 ccattgctaa tgaactccac tggaagaaag ttattggttt gtgtaatatc cctattggtc
    24121 aaaagaaact tgctgctcag attttaggcc aatcagaagg agacctaagt acgcgccata
    24181 ttgggttaaa tcattttcac tttcatgaag tttgggataa gtatggggaa aatcgtacgc
    24241 aagtaatctt agaaacattg tatggggatt tgagagagga gatgccagaa gcagtcaaaa
    24301 atattactaa tctagagttt cctattcaat tgcttcggac gattggaatg ttgccatgtg
    24361 attaccatcg ttattatttt ttggaacaag aaatgttaga ggatgctttg gaacagtatc
    24421 gtcagggtaa tgtacgagcc aaggttgttc aagaagtaga gacagaattg tttgagcttt
    24481 acaaagaccc acaattgaaa gacaaaccaa aacaactgga actacgtggg ggtgcctact
    24541 atagtgatgt tgcctgtcaa attatttgtg ctatccataa tgatagtaga gaagaattga
    24601 ccgtatctac tgtaaataga ggagttattc cctatctacc tgaaaattgt gtggtagaag
    24661 tcacctcgat tatctctgcg caaggagcaa ctccactagc ttgtccacca actccgccga
    24721 ttgtaaccgg ctatttacaa ctgatgaagc aaatggagct tgtcactgtt caggcagcaa
    24781 tgacaggtga ttattccctg gctttacaag cttttacact caacccgctt atttcaaatg
    24841 gaccacaagc tgaagtgcta ttacaagata tgttacttgc acatgagaac tatttgccac
    24901 aattcgcacc agctatacag cacataaaag agagaaggaa caatcaatga ctaaagacaa
    24961 ggtattttat caatttccaa caaatttttt gtggggttct tctacatcag gacctcaaag
    25021 tgaaggaatc gagccaggtg atggaaaagg acagaacaac tgggattatt ggtatagtat
    25081 tgagcctgaa cgatttcata acaaaattgg ccctagtcaa acatcaacat tttacaaaca
    25141 ttatgaaaaa gatattgatt tactagttga aactggacac actgtatttc ggacttccat
    25201 tcaatggtcg cgtctcatac caacaggtac tggagaaatt aatcaagagg cggtgtcctt
    25261 ctatcgttcg gttttttctt tggtaagagc aaagggaatt cagctctttg tcaatcttta
    25321 tcactttgat cttccctatt gtttacaaga aaaaggtggt tgggaaaata aggaaattgt
    25381 tcgagcctat gaagcatatg cacgtacatg ttttgaattg tttgatgatt tagtcgatcg
    25441 ttggattacc tttaatgagc cgattgttcc agtagagtgt ggttatctag gaaattatca
    25501 ttatccatgt aaggttgatg caaaagcggc agttgcggtg gcttatcata cacagttggc
    25561 aagttcttta gctgtaaagg catgccatga ggtaaatcct cacaaaaaaa tcgctattgt
    25621 cttgaatcta actcctgcct accctcgtag tgagcaagca gaggatataa aagcagctcg
    25681 aattgcagaa ttgtttcaaa caaagagctt tctagatccg tctgtgttag gagaatatcc
    25741 cgatgactta gtcgagctga ttgatgcata tggtctaatg ccagaggtca gcgatgagga
    25801 attagccatt attaaggaaa atcgtgtgga cttcctaggg gtgaattatt atcaacccct
    25861 tcgggtacaa gctccaacca atagttggaa agagggagag cctctaactc cggaatattt
    25921 ctttgcccca tatgatatgc caggtaaaaa aatgaatccg catagaggtt gggagattta
    25981 tgaaaaaggg atatacgata ttgcgataaa tattaaggaa aattaccata atatcgaatg
    26041 gtttgtaaca gaaaatggta tgggagttga aggagagcgc gcatttaaag acaatggact
    26101 cattcaagat gattaccgga tcgaatttat cgaagatcac ttaattgaat tacatcgagc
    26161 tatccaagaa ggggcgaatt gtaaaggata catgttatgg acctttattg attgctggtc
    26221 ttggttaaat gcatacaaga atcgctatgg attagttgaa ctggatctag acacgcaaga
    26281 aagaattgtt aagaaatcag gcaagtggtt caagaaattg agcgatgcta atggttttca
    26341 tcgctaggag ggaatgatgg tagaactggg cttttcaatt tatcctgaaa actattcgct
    26401 agaagagagt caagcttaca ttaaacttct gcaccaatac ggagcaaggc gcttatttat
    26461 gagtttgttg caacttgaaa atggagaccg aacagttttc gaattgtatc aaaaactaat
    26521 tgactatgca aatcaactgg ggatgactgt cattgcagat atcagtcccc attttatcgc
    26581 agcgcaaggt tgggatgggg cgttgatgga gcgtgcagca gaactggggt tggccgggat
    26641 tcgtcttgat gaagctcttc ctttggaaga aatcattgag atgacacata atccacgcaa
    26701 cataaaagtt gaattgaatt tgagtacaga taagatcttg ctgtccaatc ttttggctag
    26761 tgttgcaaac agggataata ttattgcctg ccataatttt tatcctcatg cttttacagg
    26821 tttatccgaa gagcacttct tagagatgtc atctttttat catcaatcag gtataagaac
    26881 tgcggcattt gtcagtgcac aaacagcttc tgaaggaccg tggccattat ctgaaggcct
    26941 accaacttta gaagatcatc ggttctggcc tcttcccttg caaattgctt ggatgaaggc
    27001 aacgggtttt attgattcta ttttgatttc aaaccaattt atctcggagg aggaactaca
    27061 atccattcaa acagttttaa atgaagatac aatcagcctc atggttgata ttgaggaggg
    27121 tttgactccc gttgaaagag agattgtagc gtttaatcat gtttatagag gtgatatttc
    27181 tgcttatgtt ctgcgttcaa ccatgccccg tgtggtgtat aaggacgcat ctgtaccggc
    27241 tcggtcagac caagcaattc ctgtgggacg aggtgatatc ttaattgata atgatttata
    27301 tggtcgctac aagggtgaat tgcaaattgc actcaaagaa tttaccatca gtccaaaggt
    27361 aaataaggtc ggacgaatca gcccagacta tcttcccttg ttacgcttta ttaaaccgtg
    27421 gcaagagttt aaactggtca tagcttccga gcactttcat taatgatgcg gaaaaagtag
    27481 gcacctccag aaatcgcttt catgttataa tgtacatata agaaatcaaa gactgttgga
    27541 ggaaaggagg gagcatgtta tctaaaaaag aagtacgctt gttagaggct ttacttgcaa
    27601 aacaggagac attcgtacca agcatcgaac tagccaaggt attatcagtg agtgatcgaa
    27661 cggtaagaac gtatattcat caactgacat cttctttaga aaatagcggt gctcatatcc
    27721 tttcaaaaca aggtagtggt tattgtttac agattgaacg gccagttgag tttgaaatgt
    27781 tttggcagga gcaattgctc ctaaaaaagc ggttaactga tttaactcaa ctagaagaag
    27841 cgggggatcg gcaacggtat attctcaata agctcttgtt tgaggatccg attcagtcac
    27901 cagattgttt acaaagagag ctattcattg gaaagactac gcttcattcc attttggcgg
    27961 atattcgaaa actatttatc ccctatcaat tagaactcct tgtgacacgt aaaggaattg
    28021 aactaaaggg ggatgaacct gctatccgtc actttattat ggattacttt tttgatgagg
    28081 gaaatgttca atctgtttat ggggttgtcg aaaccaatct attgccagat atacggttca
    28141 cagacttaat gttaatcgtc ttagacgagt gtcgggatgc taaattacgt ttatcggatt
    28201 ttgtcatgca gaatctagtg ctccatatcg ctcttctttt acaacggttg aaaatcgggt
    28261 ctggtctaga ccgattcccg ataccggagc gtattcagtc gtctcaagag tatcttgtgg
    28321 cacaacggat tatagaccga atcgaagaaa cgtttcaagt gacgataccg tcagaggaag
    28381 caaattacat tgcgttgcac cttaaggtaa aactaacggg gaatccaaat caagatggtg
    28441 aggtggaaga gatatttaga cagaatgtgg agaatagtct tttacatttg tcacatttaa
    28501 caggcctaga gttgtcaaag gatcagcagc tattcaaagg agttctggcc catttgatgc
    28561 cgttacgtat tcgtttggag aataatattc aactgggaaa tcctctaact gctgaaatta
    28621 aagaccaata ttttgaggct ttcgaattaa caaaaatggc atttgcagcg ataccagaac
    28681 taatggggta ttcgatttcg gatgatgagt gggcttacct taccttacat gtgatggcgg
    28741 caattgaacg ctatcaggga tttaagaaga ccagagtatt ggtagtctgt gctaccggaa
    28801 ttggaagtgc attgatgtta aagaatcgct tggagaaaga attttcatcc agcttagaaa
    28861 ttcttgatac ggttagttat tatgaagtta cagaggaacg actgaaggat gttgatttga
    28921 ttatttcatc cattagcttg tcgaatctaa tttttatgac accggttatc aatgtcagcg
    28981 tcttcctatc agagaaggac attgaggcta ttcgatctca tttacagcaa acgaccccag
    29041 ttattcctga ccaaggggaa aatgtgctaa tggaagtagg tcaggctaag cagattgcag
    29101 aagcagtatt tgctccacat agaataatct atcttgagga ggattgtgat cgagaagtag
    29161 ccttgaagca actagtaacc tctttggacg aatccattga gcctgatttt gttaatcgct
    29221 ttatagaaca agtgaattta cgagaatctt acagtccggt tgtctttggg aatcggttag
    29281 cctttcctca tccagccttg ccgatgagtt attcagaaca aattgttgta gggatatata
    29341 agaatgctgt ggattggggc catggaaagc aagttcaatt cgtcttccta ttgtcaccgt
    29401 caaagggtcg aaatgcattt ctgaagtata tctcaccttg tctggttgat tttgttcaag
    29461 atagagttct ccaagaacgt ttgttacatc atccaaatta taaagaatta attgatattt
    29521 ttattcccct cattcaaaga aaggggtagg aggagttttt tatgaaacac attatgttag
    29581 tttgtaacgc aggcatgtct acaagtatgc ttgtaactaa gatgcaaaaa gcagcagaag
    29641 aaacaggggt tgaagcaact atttgggctg ttccagtatc tgaagccgat aatgaagttg
    29701 ctcaaaaaga gattgatgta ttactcttag gtccacaagt aaaattccta ttgaacgact
    29761 ataaggcaaa atttgagcca actattaagg tagatgctat caatatgatg gattacggag
    29821 tgatgaacgg agctaaggtg ctagaggctg ccctaaaaat gatggagggg tagtatgaat
    29881 tctccagagt atcttgaagc gattatgggg ttaatcatgt acggtggtga agcaaagggc
    29941 ttcgctagcc aggcgattca agcagccaaa gaaggtcgta ttgacgaagc ggaacagctg
    30001 ctccaagacg caatagcttc attgaatatt gcccataaat cgcaaacaca attattagca
    30061 aaagaagcaa gtggagagtc tgttgaatta tctttgttaa tggtacatgg acaagatcac
    30121 ttgatgaatg ctttgacatt tattgattta gcgaaagagt tcgtagatct ttataaacag
    30181 attggataat tataggagaa ctgggttatg aagatatcaa aaataggtca agttccaatt
    30241 gagcgacttt tcgctactat tcgccaatcc ttaaaagatg attttcagca aaatacgggt
    30301 tccatcttgc aagatcaaga cattatccag ggacttactt atactaaaac atttggtgat
    30361 aagggacaac atagtgtcaa ggtaactgta gaagagttta cagctcctta ttgctatgca
    30421 gtttgtttcc attctaatcg aggaaaagag catgttcgct atcagttaga ggatttaggg
    30481 aatgatcaaa ccaatataga atattcttat gagatggagg ctggtgatat ttttgtaaaa
    30541 ggcaatcaat ttctcatgga aaaaatcttt tcaaaaagta taaaacgtca gacaaatgcc
    30601 cagttagagg cgctgattcg ttgctcagtt gagccggtat cagtttaaca tttaggaaat
    30661 ataaaacaaa aaatagaaaa ggagacagaa tatgtcaaat atttctgaga agttcatgga
    30721 aatatctgga aaaattggtt cgcaacggca tttgattgcg attcgtgatt cctttatttc
    30781 tatgatgccc attacgatgg caggtacagt ggccgttcta ttgaatgtct ttctgagaga
    30841 catcccaaat aatatgggat ggactggttt tgctgatgcc atgcaaccag tgatagatat
    30901 caatggttac gtttattttg gaactatcgg gataatggca cttgtatttg cctttacctt
    30961 tggttacaat ttgtcactca tgtataaggt gaatccttta gcaggtggtt taatttcctt
    31021 tgcatcattc atctctacta ttcctcaaag tgtaacgatt tccactgctt tagacggagt
    31081 tgataagtca gttgtttctg ctttggaagg tttgggatta tccattgtga cgacagatgg
    31141 agtttcagcc ttggaaacaa gccagtgggg agctatcgca ttgaaatatg gcggtgcaac
    31201 aggtttgttt acagcattgt ttattggatt tctcgctaca tgggtctatg caagtcttgt
    31261 aaaacggaat gtcattatta aattgccaga ttctgttcca ccggcagtta ataaggcctt
    31321 tgctgctatt atcccaggta ctgctgcaat ttatgcgtca tccattgtgg catatcttgc
    31381 atttactcta acaggacaat ctttgggaga tttagtatca acttatattc aactgccatt
    31441 acttggtctg tcacaaggtc ttgggtcagt cattctttta actttccttg tacaactttt
    31501 ttggttcttc ggcctgcatg gtcacaatgt cttggcgcca attatggacg gagtctatat
    31561 ggttgcacta aatgaaaatg cggctgctta tactgcaact catagtactg cgaatttacc
    31621 gtggctttgg actcgtggtt cctttgatgc ttatgctcaa atgggtggtt caggcgtcac
    31681 tctagctttg attattgcta ttttcatttt ctcaaaacga gaagaataca aaatggtagc
    31741 taaattatct gctccaatgg gtgtattcaa tattaacgaa ccagttacct ttggtatacc
    31801 aatggtattg aatccactgt ttgctattcc atggctaatt gttccaccga tttgtgcaac
    31861 tatcgcatac ttagcgacag cggcaggtat aattccgcca gtctttgctc ctgttccatg
    31921 gattacccct ccaggactct acgcttatct agcaacaggt ggtaacatta tggctgcgtt
    31981 ggtttcacta ttcaacctct ttgttgcctt cctgatttgg acaccatttg ttattgcagc
    32041 caataaggtt aaggctggtg aggaataatg ttttccaaga acaaatctcc tttcttattg
    32101 gcgctaggat ttttccttat cgcgattagt ccgctttatg ggaataaata tctaaacatt
    32161 atatctggtt tggtttttat tctaatcagt gtactcagga gtaggagaaa ataattacac
    32221 taacactaaa tagaaaacga cttccgtatt ggaggtcgtt tttttgacaa aaagtccgga
    32281 cactgtgatt gttaagagat tgcaagttat ctgtaatatt tgttacattc ctttaagctc
    32341 tctgcaagga ttatccttta ggatagatag ggcagaaaaa cacgaaggaa tcaaatatta
    32401 tgagttatca aatgataaaa aaacaattca aattgggact gtttacagcc ctcataggaa
    32461 atcttttatg gttgggaatg gtgaatgtca gtgcagatga cacagttata agcgatagtc
    32521 cgacagtatc agcgttaaca aaaaaggttg aagctgcaaa aatagcagcc aaagctgctg
    32581 cagaaaaaat tgtggctgag aaagctgctg ccgctgcaaa ggctgctttg gctaccaata
    32641 tggtgtcaga ggttgctttg gaatatacgg ctaataccta tccagcgggt cagtgtactt
    32701 ggggtgccaa agaaatggct ccttgggttg gaaactattg gggtaatggt ggagattggg
    32761 cagctagtgc ggcagcgctt ggatatgaag tgggaactac tccaaaagtt ggcgctattg
    32821 ctgtatggac agatggaggc tacggtcatg ttgcctatgt aacagatgtg gcagctaatg
    32881 gtcacattca agttaaggaa tcaaactatg gtggagtata ctacccaagt aatgtccgag
    32941 gtttctttga tccaacaacg actagcgaag gaacagtcag ctatatttac ccaccagctg
    33001 gagtaaatta atatgagata taaagaccga gtaggtcttt ttttatgctc cgatacttga
    33061 ttaaaatttt taatgtcccc gatagaaaaa atatattggc tggaaattgt tattcatgat
    33121 actattgtaa aatctgaaaa agaaagtgtg ttttaattat gaagaaaata gctatgttta
    33181 caagtttatt gtttgcgggt atcgtgttag cagcctgcaa ttcatctgca ggtacatcga
    33241 atagtacaga ccaaaccctc ttggcacaaa ttaaggaaga aggcgttatt caaatcggta
    33301 ctgaaggtgc ctatgctcct tactcttacc acgatgagag cgggaaattg gtcggttatg
    33361 atgtagaagt agccgaagcc gttgctgaga aattgggtgt taaggtggaa tttgttgaaa
    33421 cagaatggga ttccatgatt gcaggtttgg atgcggcccg ttttgatacc atcgctaacc
    33481 aagtcggtat tacagatgag cgtaaggcaa aatacgattt ttcaacacca tatacataca
    33541 tctatggagc cttggtgacg caaaaagata atactgacat tacaagcttt gcagatttat
    33601 ctggtaaaaa atctgccaac agcttgacaa gtaactgggc agatttggct cgtgaaaatg
    33661 gtgcagaagt tgtcggtgtg gatggattct ctcaggcagt tgaattgtta aatacaggac
    33721 gtgtggatgc taccatcaat gacaacttgg tgtacttgga ttatgtgaaa caacatgctg
    33781 atgcaccgat taaggttgtg accttgacgg atgacgtatc gacaacagcc ttcccagttg
    33841 caaaaggaaa tgaagatctt gtgaaagaga ttgatgcagc cttggcagaa ttggctagtg
    33901 aaggaaaatt agctgaaatt tcaaacaaat actttggtga agacgtatca aaagctaagt
    33961 aatcaggaga aacaatgaca gagagagtat ggcaactatt gcttgattca ttttcacaaa
    34021 tacttgttcc aggattgttg gtgactatcc cactgacaat cctgtctttt acctttggct
    34081 tgttaattgc tattgggacg gccttggtgc aaattgctca gattcccatt ctcaaacaag
    34141 tggctcgttt ctatatttgg gttgttcgag ggacaccact cttggttcaa ctctatgtga
    34201 tattctttgg gctaccaagt ctaggaattg tcttggatgc ttttccgtcg gcggttttgg
    34261 ttttttctgt caatacaggt gcctacgctg cggaaaccat acgggcttct atcgagtccg
    34321 tgcctaaggg gcagttggag gctggctatt ctgtcgggat gagttttgct cagaccatgc
    34381 gtcggattat tctcccacag gcctttcgag tggccttccc gcccttgtcc aatactttga
    34441 ttggattggt caaggataca tcgctggctg ccaatattac cgttttggag atgtttatgg
    34501 caactcagca gattgcagca aggacctacg aaccgtttgc cctctattgt gaggtggccc
    34561 ttgtttatct attcttttca actattttga ccaagcttca agcctatggt gagaagaagt
    34621 tggcagtcta ttaggaggtt cagatgattc aagcaaatgg agtaaagctg accttcggtg
    34681 gtcagcaggt gttaaaaggg attgatgtag aggtcaatcc aggtgaggtg gtcgtcattt
    34741 taggcccgtc tggatcggga aaaacgactc ttcttcgttc tttaaacttt ttggaaaaag
    34801 ctgacgcggg tcacttagtc ttcggtgagg acagctatga cctggctcag atgaccaaga
    34861 aggaaattgc aggcattcgc aagcgcacag ccttcgtttt tcaaaactat aatctctttg
    34921 ccaacaagac tgccttacaa aatgtgacgg aaggcctgat tgtggctcgg aaagtaccca
    34981 aacaagaggc tgaaagaatc ggtaaagcag ccttggacaa ggtgggacta tctgataaat
    35041 atggtttcta tccaagtcag ctgtccggtg gtcagcagca acgggtcggc attgccagag
    35101 ccattgcgac caatcccgag gtcatctatt ttgatgaacc aacctcggcc ttggatcctg
    35161 agttaatcgg tgaagtcctg gctgtcatga tgcagttggc aaaagaaggt atgaccatgg
    35221 tggttgtgac tcatgaaatg ggctttgcgc gtgcggtagc tgatcgagtc atatttatgg
    35281 atggtggtcg gattatcgaa gaaggtcgac cagaagatat ttttgaccag ccaaaagaag
    35341 aacgtactaa gcaattctta gctcgcattc aaaaggtaga tgttgagtaa gctaagcaaa
    35401 ttaatttatc ttattcattt ccataatcgt acagaaaatg gacagaattt gacaaagata
    35461 cttcaattgt tagacattga ttggtctagc agttggagta ttttttgttt agagggaatg
    35521 ggtattctta tatagtactt ttagcacgag gcgatgagcc gcaggcatag atgaagttag
    35581 gcaaggtgag ctaaggaagt aatagaagga aaactaaata acgataaatg tattcgaaag
    35641 gtctttactt tttagtaata aatagtatat aataacctaa agaaaacgtt tgcacaattt
    35701 tgactgtttg cttgctaaaa gataagcaac agaaatagaa ttagggagga gttctatgac
    35761 gacattagcc gatgtggcta ggttagccaa tgtatcaaag atgactgttt cgcgtgtcat
    35821 caaccatcca gaacaagtta cacaagagct gcggacgctc gtaacagctg cgatggaaga
    35881 attaaactat aagccaaatg tggcggccaa ggccttggcc cagcaacgga cactgattgt
    35941 tcaggctgtc attctcgaaa agatggatgt ggtagagccg tactatatcg accttcttgc
    36001 aggaatcgct gatgagctca atcatcgaaa ttataccttg cagttggtga ccaatccaag
    36061 tcagatcact gatcaatgtg atggttacat tgtgactggc gctcgcaagg atgactaccc
    36121 ttggttgaaa gggctgcgga agccattgat tttatttggg gagaatcaag aaggccttcc
    36181 ttttgtagat tcagacaatc gtttggcgac taggtccgca acccagtttg ctttatcaaa
    36241 aggttatgag aggattgttt ttgtagggat tgacttgcca gaagcctttg aaaaagggag
    36301 agaagaaggc tacaaagatg cgatgcaggg ccgagaaact catctctatc gattggaaaa
    36361 tcgttctcgt gttgcggaag aatttgtgaa aaatcttgat tatttaccag aaaacacctg
    36421 ctttatctgc gcatcggatc gtctcgctct tggggttaca agaggtttac aagctctagg
    36481 aaagtctatt ccgaatgacg ttggggtgat tggttttgac ggcttctttt tagataggat
    36541 gtccagacca gccttgacga cgatgaagca gccgattcgt caaatggggg ctcttagcgt
    36601 caaacattta atgacgatat tggatggcaa gcctctggct agacaggggc attactgcca
    36661 ggcaacctta attgaaaggg agactacacc tcagtagtct ctttttttgg tcagtgggcg
    36721 gtctaggagc aaaagaaggg ggagctattt attctatttt tgttagatag tagctcaaaa
    36781 cttgttaccg ttaacattta agaaaacgtt tgcaaagact ccttggaatt gtatatactg
    36841 gtagtgtaca attcaaactt atttatatgg aggagtctat gaaaaagaaa tccgttcaga
    36901 atatgaaacg aacagggatg ctagagaaga aacagatttt tggcattcgt aaactaaatg
    36961 taggtgtagc ctctgttggg attgcggctg ctctgttttt aagtggagca ggtcaactag
    37021 tgcaggcaga ggaagttgtc ctccctgcgt caactagttc aacgactctt tcggaacagg
    37081 atggcggcgc ggtagaagcg accacaactg cgatagaagc tacagattct atggtagctg
    37141 aagcgacagc ggtaacagaa acagccgatg caactgctcc agaggaagct cctatcgaag
    37201 aaggcagcat tcgtctgcac tttgaaaatg tagatgaaac agcaccagaa agtcaaggac
    37261 tttggacttg gggaggagtg gcagagccgt ccgatggtaa tcaatggcca acggatacag
    37321 cgaacttttc aagcagtcag gtagatgact acggccatta cgttgatatt aaaaaatctg
    37381 agacaccagg aacgattggt tatctggttc tcaagaatgg ggaaaaaata acagaatcgg
    37441 accagaaagt ggagctactt gttccggaac aaaatgaggc ttggattgct agtgattata
    37501 gcgtgtctag ttatgagcca ctcaaagatg aaaatgtcct ccgtatcaac tacacccgtg
    37561 aagacaataa ttatgaaggt tggggcgtat ggacttgggg agatacgact gaagcaagta
    37621 gcggctggcc agcaggtgcc gttgacttta aacttggcaa atacggcgcc tatgttgaca
    37681 ttcctctatc gaatggttta gattccaagc ttggatttct gctaatcaat cagaataatc
    37741 cagatttggc aggcaataaa acaattgatt tagcctttgc agatcgtaaa cggcatagcc
    37801 aaattttcct tcgcaatgac gacgacaaag tctataccaa tccatatttt atcgaagaga
    37861 aagtagaact cgatacaagt aaagctactc caggtacaaa aaatgtgact gttggggcaa
    37921 gtgtgaaagc accattcaac tacaatgaaa gtggcttggt atctgtaacc gtcaccaacc
    37981 ctgaaaatgc tgaaatagtc aaaatggaag tcgatacaag tgccatcggt ggaggtcttg
    38041 tgccaatctc tactgagctc aatcgtgtga ccattaaagc gacgtctagc acagcgccag
    38101 ggacatatag tcttcctgta aaggtctatg acaaggacaa cggttactac gaaacaaaat
    38161 tggatgtgac cattacagag cgtatcaagg cagatggtga aaaagactgg gacgagcaag
    38221 tcatctactt catgatgaca gaccgtttct ataatggaga caccggcaat gacaagctag
    38281 tggaaggaac agcctccaac ccacgcggtc tttaccaggg cggtgacttc aaaggagtga
    38341 cagccaagct ggactacttg aaagaattgg gtgtggactc tatctggttg actccgattg
    38401 tggaaaatat tccacagaat gttggtagcg taaaagatgg agaatactat gcttatcatg
    38461 gttattgggc atccaatttt gagaaactaa atccgcattt gggaagttta gctgatttcc
    38521 acgaattgat tgatgccgca gccgaaaaag gcatcaatat tattgttgac gtggtgctta
    38581 accatgctgg ctatggtaca gaagaaacct ttgcaggtat ggtacggact aaggaagaag
    38641 acaagcaggg agatgaccaa ttaggctcat tatctggatt accagacttc aagacagaag
    38701 aagctgctgt tcgcaatcag ttggttgctt ggcaggcatc ttggttggaa cgttcaacaa
    38761 ctgccaaggg caactctatc tatgctttcc gtgtcgatac agtcaaacac gttgatgata
    38821 ccacatggca acatttcaaa aatgaattgg tggatagaga tcctgacttc cacttgattg
    38881 gggaaacttg gggagcgaat tataaggata ccaagggtga cttgggtatc ggcactatgg
    38941 atagtttgtt ggactttggc ttcaaggata tcgccaaata tctggtcaat ggtcaactaa
    39001 aagcagctgg aaaagagctg gaagaacgta gcaaggttct gactagtgca gcttctctgg
    39061 gtcaattctt gggcagtcac gacgaagatg gtttcctcta cagtctcggt ggcgcagaaa
    39121 aagaaggaaa tctggacaaa ctgaaattgg ctgctagtct tttgattact gctaaaggtc
    39181 agccagtcat ttactacggt gaagaagtgg ggcaatctgg acaaaacaac tggccagttt
    39241 atgacaaccg gtacgatttc gattggagca aggtagagac tagcgacatc acagaccact
    39301 atcagaaatt attggctttc cgcaatgcca attcaacatt gctctcacgt ggtgatacaa
    39361 gcacacttgc tggaaatgat agccaaggtt ggcttatcag caaacgcagt taccaagatc
    39421 aagctgccta tcttgtcttc tcgaccaata ccgagaacaa ggaaatggcg cttgaagtat
    39481 ctggtaaaga tgtagttgtc acagatgcct atacaggaaa atcttatcaa gctatcgaga
    39541 aagacggtaa atgggttgtt caagtcgaac tgccaacaat cggtcaaggt ggcaccatgc
    39601 tccttcagac agaagcaggt gacatcgtca atgcaagtgt gcaaggagca actgaagaac
    39661 caattgaagc aggctacttc cgtgttcact ttaaaactct accatctgat aatttatcta
    39721 gcctaggttt atggacatgg gatgatgtcg aaaaaccatc gtcagatctt ggtgcttggc
    39781 caacaggtgc aaccaatttc agcacggcta aacaggatga ctatggctat tatcttgata
    39841 tcaagatgaa agatgaaaca gccagcaaga ttagtctgtt gattaataac acttctggtg
    39901 ataacatcac aggtgacaag accattgaac ggattagcac caagatgaat gaagcttggt
    39961 ttgatgagaa ttatcaactc agcctctatc aaccacttaa agaaggctac atccgtatca
    40021 attacttccg taccgatggc aattatgatc aaaaaggtct ctggatctgg ggtgatgtga
    40081 ctgaccttac cctgggtgac tggccaaatg gtattgattt tgaaaaccaa ggcaagtacg
    40141 gtgcctatat tgatgtcaaa ttgacagatt taccaagttc cattggcttc ttgctattgg
    40201 atgaaagcaa gtcaggagac gatgtgaaga ttcagcagaa agattatagc tttaaagatt
    40261 tgaaaaatca gacacaaatc ttcctcaagg atgatgatgc gactatttac accaaccctt
    40321 attttgtcaa taatgtccgt gcgacaggtg tttctcacgt tagcctaaca gccttagaag
    40381 cagcctttac aacattggaa ggtgcggata aggatagcat cttggagaaa ttgtctgtaa
    40441 cagataagaa tggtcagaca gttgcagtga cggaccttgt cttggacctt accagcaaca
    40501 aggtgcgagt cctcggggat ttcaaccaag aaaatgcggg ctataccctc aaatatggca
    40561 atgatagctt cacaacaact atgagctggc agttgaagga tgagctctat gcttatgatg
    40621 gagagcttgg tgcgcgtgtg cgtcaggctg gtagtgtcgt tgatatgact ctctggtctc
    40681 caagtgcaga cagtgtggca gtcgttcttt atgataagga tgatcaatct aaggtggtcg
    40741 gtaaattggc catgaccaag ggggataagg gacaatggga cctcgaattg aacagccaat
    40801 caggtcttgg tatcgcggac tatcgtggtt actactacca ttatgaaatc actcgtgggg
    40861 atcaatctgt tcttgtttta gacccatatg ctaaatcttt agcggagtgg aatagtgatt
    40921 tggcagatac agatccatct tatcggattg caaaagctgc gattgtggac ccagcagaag
    40981 ttggtccaag tgatttgaac tatgccacaa ttcctaactt caatcagcgt gaagatgcta
    41041 ttatctatga ggctcatgtc cgtgacttca cagccgatcc tgctatttcc gatgaattga
    41101 ctgctcagtt tggtaccttt gctgcctttg cagagcgtct cagctacctc aaggaattgg
    41161 gtgtgactca tattcaatta ttgcctgtta tgagctacta ttttgtcaat gaattgaaaa
    41221 atgcagagcg gatgagtgag tacgcgtcaa gcaacagtaa ctacaactgg ggttatgatc
    41281 cacagagcta ctttgccttt acaggtatgt attctacaga tccgacagat ccaatgaaac
    41341 gtatcgaaga gttcaaaaat ctggtcaatg aaatccacaa acaaggcatg ggtgtgattt
    41401 tggatgtggt ctataaccac acttctaaga ccttcttatt tgaagactta gagccaaact
    41461 attatcactt catggaggca gatggtacgg ctaaatcaag ctttggtggt ggtcgtctgg
    41521 ggaccactca ctacatgagc cgtcgtgtct tagttgattc catcaagtat cttgtggatg
    41581 agtttaaggt agatggtttc cgcttcgata tgatggggga ccatgatgcc gaagcaattg
    41641 agctggcctt tactgaggct caaaaactca atccaaacat cattatgctt ggtgaaggat
    41701 ggagaacctt tacaggtgat gctaatcagc ctgttcagcc agcggaccaa gactggatga
    41761 gttcaacaga tacggttgcg gtattctcag atgaaattcg caatacactt aaatctggtt
    41821 atccaaacga aggtcagcca gcctttatca caggcggtgc taagagtgtt gagtctgtct
    41881 tcaataacat caaggcacaa ccaggcaact tcttggcaga tgatccaggt gatgtgatcc
    41941 agtatattgc tgcgcatgat aacttgaccc tctttgatat tatcgctcag tccatcaaga
    42001 aggatccgtc agttactgaa aactatactg aaattcacca acgtcaacgc ttgggtaatt
    42061 tgctagtttt gactgctcaa gggacaccgt ttattcattc tggtcaggag tatggacgga
    42121 ccaaacagtt ccgccatcct gattataagg aaccagttac agaggacaag gtaccgaaca
    42181 aagcgcattt gttgacaaat gctgatggta caccatttga ctatccatac tacattcatg
    42241 attcttacga ttcatcggat gcggtcaaca agtttgactg gaccaaagcg acagatgagg
    42301 cgctctatcc agagaatacc cgtactcagg cctttacaaa aggattgatt gccttgcgca
    42361 aatctacaga tgccttccgt ttgggaacaa aagaagaagt tgaacagaag gttagcttga
    42421 tttcaattcc aggtcaaaat ggtattgcta aaaatgatgt ggtcattgcc tatcaaacca
    42481 ttgcaagcaa tggggaccgc tatgctgttt ttgtcaacgc cgacagtaag gagcgcagct
    42541 ttgttctttc tgatatttac aaagaattgc ttaagggtca agtgctggtt gacggtgaac
    42601 gtgcaggtgt agaagcattg tctgatttag tgggtgtcga attgactgat agctcagttg
    42661 ttcttgcacc tttgactgca acagtgattc gtttgcctta tatcactacg gcgcttccag
    42721 atacagcgcc tactgctgaa gaaaaaccaa gtctagactt tactaccaag gaacgtacag
    42781 aagaaacagt ccttccgatt gcagaggaag ttcgctatga tgcaacactt gcaaaaggtc
    42841 aatcttatgt gcttcaagaa ggtaaggcag gtaagagagt cttagtttat caagatgtct
    42901 tggttgacgg caaggtagta gcaacaaatc tgttatctga aacagttgta gatggtgagg
    42961 cgcggattgt tgttaagggt agtatggagg ctaaggatgt ggtagaaaaa ccaagtcttt
    43021 ctactccaac agctcaagcg tctggacaag cgacaagtgg tgcaagcaag gcgagtctgc
    43081 cgattacggg tgaccgacaa agcgatttgg cacttctagg tctcggactt gctggacttg
    43141 gtttgacagt tgctgcgcaa ggaagaacta aaaaatcaga agagtaataa tatttggctc
    43201 tccagaggag cattactcaa aaccttgtga atttcttata aatacaagag ttgagagtat
    43261 cacttccctc tagaagaggt tggtttcaaa ccaacctctt cttttaaatt tttaggtaaa
    43321 ataacgtcta tttattgatt attagaataa atgggctggt gaactatagg gaggaattct
    43381 gattaaatca gccattaaag ttcggaaata gtccaatagt gaacacaagc ctgtgcttta
    43441 tttggtcttt ttgtttccgc ttacataact tataataaaa ccataaaaat catttcaaaa
    43501 aaggagaatg aaaaatggat ttccttcaaa ccccattaaa ctggttctca cagaatatcc
    43561 tgcagaatcc agccttcttc gtaggtcttt tagtgttggt gggctatgcc ctcttaaaga
    43621 aaaagcctca tgatgttttt gcagggttta tcaaagcgac agtcggctat atgattttga
    43681 acgtagcagc cggtggtttg gtcacaacct tccgtccgat tttggcggct ttgaactata
    43741 agttccaaat tgatgcggca gttattgacc cttacttcgg tcttgcagca gcaaatggga
    43801 aaattgctga ggagttccct gatttcgtat cagcagccac tacagcgctc ttgattggtt
    43861 tcggtgtcaa catcctcttg gtggcactac gtaaggttac caaagtacgt actctgttca
    43921 tcactggaca catcatggta caacaagcgg caacagtctc attgatggtg ctcttcctca
    43981 tcccggctct tcgtaaccaa ttcggtacag cagcgattgg tatcatctgt ggtatctact
    44041 gggcagtcag ctcaaacatg acagttgagc caacccaacg attgataggt ggcggtggat
    44101 ttgccatcgg tcaccaacaa caattcgcaa tctggtttgt cgataagatt gcaccaaaac
    44161 ttggtaaaaa agaagaaaac ttggataact tgaagctacc tagcttcctc aacatcttcc
    44221 acgatacagt tgttgcttca gcgacattga tgcttgtatt cttcggtgtg attttgttca
    44281 tcttgggtcc agaaatcatg gcaaatccag aagttatcac ttcaggtgct ccatacaacc
    44341 cagctaaaca agccttcttt atgtatgtga ttcaaacagc cttcaccttc tcagtatatc
    44401 tcttcatttt gatgcaaggt gtccgcatgt tcgtagcaga attgacaaat gccttccaag
    44461 gtatctcaag caaattgctt cctggttcat tcccagcggt ggacgttgca gcttcttacg
    44521 gctttggttc atctaacgca gttctttcag gttttgcctt cggtttaatc ggtcagttga
    44581 ttacaatcgt tctcttgatt gtcttcaaga gtccaatcct catcatcact ggtttcgtac
    44641 ctgtattctt cgataacgca gctatcgcag tgtacgctga caaacgtggt ggttggaaag
    44701 cggcagccat cctttccttc atctcaggtg tccttcaagt tgctcttggt gcagtctgcg
    44761 ttggcttgct tgaattgagc ggtggttacc acggaaacat tgactttgaa gtgccatggt
    44821 taccatttgg atttgcattt aagtacctcg gtattgctgg ttatgttctt gtctgcctct
    44881 tcttattggc tattccgcaa cttcaatttg cgaaagcaaa agataaggaa gcgtactatc
    44941 gtggcgaggc acaagcagaa tagtatcctt ggtctgtaaa atcagaacat aatgtattaa
    45001 aaataaaata ggagtgaaat tatggttaaa gttttaacag cctgcggaaa cggca
//
LOCUS       DBNFCO010000006        42619 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.006, whole genome shotgun sequence.
ACCESSION   DBNFCO010000006 DBNFCO010000000
VERSION     DBNFCO010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 42619)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42619)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42619
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.006"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(127..1869)
                     /locus_tag="AC1PIV_000288"
     CDS             complement(127..1869)
                     /locus_tag="AC1PIV_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spy0128 family protein"
                     /protein_id="HIP6611343.1"
                     /translation="MNTKKWRTSLLIPGIVLFGTVALVNNVSAQEVKNTIISAKQPDG
                     GQATSKAVNVKIPAVVRLFGRELLENEFKFELREANGEELPVLDTAQNTKEGQVRFKN
                     LSFDKPGKYWYTISEVKDELGGIEYDSKYIVAKITVEDRNGQLQAMIEFIDNDNVFNN
                     FYTPAPAAASLSIKKVLEGRTLNTGEFEFVLKNEKGDEIEKVSNQADGSVNFSALTFT
                     KEGTYTYTVSEVDGGLGDIIYDKSDIKATVTVKDNNHGQLVSTVTYENSDQIFENILN
                     PGKLIAPTTDSVITDNEVSKEAMTGKEKGNIEPPKEQIANEEKDNIEASEKQMPSIVN
                     DMVVTPEKQMTNKENDKVVISEKQMPSVVNENAVTPEKQMTNKENDNIETSEKQMPSV
                     VNENAVTPEKQMTNKEKDNIETSEKQMPSIVNDMVVTPQEQMANKENDKVVISEKQMP
                     SIVNDMVVTPQEQMANKENDKVETSEKQMPVNEKDNAVTPEKQMANKEKENIETSKKQ
                     IPVNENNQNGTVEENSNTKPTTEKTDKQETSTFKTETAKQILPVTGEKGSLWLLTSGI
                     IGLAIALFTRKRKL"
     gene            2179..3177
                     /locus_tag="AC1PIV_000289"
     CDS             2179..3177
                     /locus_tag="AC1PIV_000289"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004192896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HIP6611344.1"
                     /translation="MKVLLYLEGKTVLEKSGIGRALQHQMEALDMAGIPYTTDLLGDY
                     DVIHINTYGPRSWLLLHAAKRSGKKVIMHGHSTKEDFQNSFIGSNTLAPFVGKYLASM
                     YQKADFVITPSEYSKKLIQSYGVTTPIIAVSNGIDLDKYKKDERKEAIFREHFKIEEG
                     QPVVVCAGLYFRRKGIEDFVKVAEKMPHVRFIWLGSINKWLIPSYIRKIVEGDHPANV
                     EFPGYFKGAVFQGAMSGANAFFFPSYEETEGIVVLEALASHQHVVLRDIPVYDGWIDE
                     NVAELGHTVDDFVDSIQKILDKQVDKREAGYQVAVSRSIDNVSHQLVDAYRQVLEM"
     gene            3178..4491
                     /locus_tag="AC1PIV_000290"
     CDS             3178..4491
                     /locus_tag="AC1PIV_000290"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HIP6611345.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKLGHTVFIFTTTDED
                     VNRYEDWDIIRIPSVPFFAFKDRRVAYAGFTDALKIASRYKLDIIHTHTEFSLGILGK
                     MIAKELDIPVVHTYHTQYEDYVHYIAKGRIIRPGMVKYLVRAFLKDLDGVICPSEIVE
                     DLLMSYNVPISKRVIPTGIDLAKFDRPEIGKDETDELREQLGIASDETMLLSLSRISH
                     EKNIQAIVQAMPKILLENPKVKLVIVGGGPYTDDLQEMIAELNLDEHVQLTGMIAPSD
                     TALYYKAADFFISASTSETQGLTFLESLASGTPILAHSNPYLKNVITDKMFGTLFIRE
                     QELADAVVEAIVATPPMNPYVLDKKLYEISSTNFGRKVFEYYLDLKISYDFRKEHTNQ
                     DSVAEALIKEAIYLPQKVVVKSTDTTAKILKKSVEQVKSIRNFFE"
     gene            4506..4880
                     /locus_tag="AC1PIV_000291"
     CDS             4506..4880
                     /locus_tag="AC1PIV_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611346.1"
                     /translation="MEKLRKESWKNLVLATLIILSMYAGIYLIAFHLISDTMLSKELV
                     VGNILLYTPIVLFLTGLLYGFFHGFSPSLLVLVLLLYPVTIFFFKEWIILYQIVYTLC
                     ALIGNGIGALLFSLRKKMRKNP"
     gene            5139..5459
                     /locus_tag="AC1PIV_000292"
     CDS             5139..5459
                     /locus_tag="AC1PIV_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HIP6611347.1"
                     /translation="MLPDDLLRRCQDVRRAYRELEIKHHDKEWSIDEDLLALTNDIGN
                     MNRLIMTKQGRYYDETPYTLEHKMAENIWWLIELADRLDIDIQKEMETFLAQKEELLG
                     IKNK"
     gene            5473..7425
                     /gene="thrS"
                     /locus_tag="AC1PIV_000293"
     CDS             5473..7425
                     /gene="thrS"
                     /locus_tag="AC1PIV_000293"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HIP6611348.1"
                     /translation="MIKITFPDGAVREYQAGVTTFEIAESISKSLAKKALAGKFNGKL
                     IDTTRAIDEDGTLEIVMPDHDDALDILRHSAAHLFAQAARRLFPDIKLGVGPAIQDGF
                     YYDTDNAAGQISNEDLPRIQEEMMKIVKENFPSERREVTKEEALEIFKNDPYKLELIH
                     EHSDDEGGLTIYTQGEYVDLCRGPHVPSTGRIQIFELLNVAGAYWRGKSENPMMQRVY
                     GTAWFDKKDLKAYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRT
                     LERYITDKELASGYQHVYTPPLASVELYKTSGHWEHYSEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVYKNHVRSYRELPVRIAELGMMHRYEKSGALTGLQRVREMTLNDGHIFVTP
                     EQIQEEFKKALQLIIDVYADFNLNDYRFRLSYRDPEDKEKYYDNDEMWENAQRMLKGA
                     MDEMGVDYFEAEGEAAFYGPKLDIQVKTALGNEETLSTIQLDFLLPERFGLTYIGADG
                     EEHRPVMIHRGVISTMERFTAILIETYKGAFPTWLAPTQVTMIPISVEAHLDYAWKVA
                     KELQDRGVRVHVDERNEKMQYKIRQSQTSKIPYQLIVGDKEMEDNAVNVRRYGSKATQ
                     TQSVSEFVDHILADIARKSRPAEAAE"
     gene            complement(7497..8156)
                     /locus_tag="AC1PIV_000294"
     CDS             complement(7497..8156)
                     /locus_tag="AC1PIV_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HIP6611349.1"
                     /translation="MNYVLELLKPSTFQLLWSGLKLTLYISSISVILSILFGMILAIM
                     RNGKNPIFKWIATIYIEFVRNVPNLLWIFTVFLVFQMKSTPAGITAFTIFTTAAMAEI
                     IRGGLNAIGPGQTEAGLSQGFTPVQIMVYIIMPQAIRKMLPAIISQIVTVIKDTSFLY
                     SVIALQELFGSSQILMGRYFEAEQVFALYIMVALIYFSINFAISSLSRYVAKSWASSI
                     E"
     gene            complement(8171..8869)
                     /locus_tag="AC1PIV_000295"
     CDS             complement(8171..8869)
                     /locus_tag="AC1PIV_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HIP6611350.1"
                     /translation="MTVLTTSPYAWENWVSYFKDFPIFFQGFLFTLAISVGAFIMAMF
                     LGIVFGSLSSSKNKVLKIIARVYVEYYQNTPLLVQFMIVYYGLPLISNYVLMPSIYWT
                     AVICVGLYHGAYIAEVIRAGIEAVPTGQTEAALSQGFTQSETMRIIILPQAIPTILPP
                     LTNQVVNLIKNTATVAIISGADIMFMTKSWSAMNANYIPAFAGAAFLYFIMCFPVASW
                     GRRIEEKNKSAFSH"
     gene            complement(8884..9721)
                     /locus_tag="AC1PIV_000296"
                     /pseudo
     CDS             complement(8884..9721)
                     /locus_tag="AC1PIV_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646622.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
     gene            complement(9732..10493)
                     /locus_tag="AC1PIV_000297"
     CDS             complement(9732..10493)
                     /locus_tag="AC1PIV_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015424 - ABC-type amino acid transporter
                     activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HIP6611351.1"
                     /translation="MALVEFKDVNKYYGDYHALRNINLEFEPGQVVVLLGPSGSGKST
                     LIRTINGLEAIDEGTLIVNGHDISSTSIKELVSLRKEVGMVFQHFNLYPHKTVLENVT
                     LAPIKVLGINKATAEKTAQKYLEFVNLWDRKDSYPAMLSGGQKQRVAIARGLAMKPEL
                     LLFDEPTSALDPETIGDVLAVMQKLARDGMNMIVVTHEMGFAREVADRIIFMAEGEVL
                     VDTTDVNGFFDNPTEPRAQQFLSKIINHESDKVKL"
     gene            10687..11391
                     /gene="yycF"
                     /locus_tag="AC1PIV_000298"
     CDS             10687..11391
                     /gene="yycF"
                     /locus_tag="AC1PIV_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator YycF"
                     /protein_id="HIP6611352.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALEVFEAE
                     FPDIVILDLMLPELDGLEVARTIRKTSNVPILMLSAKDSEFDKVIGLEIGADDYVTKP
                     FSNRELQARVKALLRRSELAETQTNIESTGTPELVIGDLVILPDAFVAKKHGKELELT
                     HREFELLHHLAKHLGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPE
                     YILTRRGVGYFIKGND"
     gene            11384..12733
                     /gene="vicK"
                     /locus_tag="AC1PIV_000299"
     CDS             11384..12733
                     /gene="vicK"
                     /locus_tag="AC1PIV_000299"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HIP6611353.1"
                     /translation="MINQLRYLMTTAEFWFVVILIGFLIALTVLLIENYWDNKQIKQL
                     NQKVNALIEGNYADLLDMRGSPEITDMANSLNDLSEVIRLTHDNLEQEKTRLTSILSY
                     MSDGVIATDRIGRIIMINDMAQKQLGLSNPKQEQYHLLEVLDLSDRYTLRDLLAQTPE
                     IVIDHTNENEEFLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALTESVAPSFVKVSLDETNRMMRMITDLLSLSRIDNQVG
                     QIDVELINFTAFVTFILNRFDQMKNADSDKVYTIVRDYQISPIWVEIDTDKMTQVLDN
                     ILNNAIKYSPDGGTITFSMKTTDSQLIVSVSDEGLGIPKADLPRIFDRFYRVDKARSR
                     AQGGTGLGLAIAKEIVKQHKGFIWAKSEYGHGSTFTIVLPYSKDIALDEWDDSDEEE"
     gene            12740..13543
                     /locus_tag="AC1PIV_000300"
     CDS             12740..13543
                     /locus_tag="AC1PIV_000300"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009910233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HIP6611354.1"
                     /translation="MIGKGFNYSILASGSSGNCFYLETDKKKILVDAGLSGKKITSLL
                     AEIDRKPEDIDAILVTHEHSDHIHGIGVLARKYGMDIYANELTWQAMESKLGKIDVAQ
                     KHIFELGAMKTFGDLDIESFGVSHDAACPQFYRFMKDDKSFVMLTDTGYVSDRMVGIV
                     ENADAYLIESNHDIEILRAGSYSWNLKQRILSDKGHLCNEDGADAMIRSLGNRTKKIY
                     LGHLSKENNIKELAHMTMVNQLAQADLGVGVDFQVYDTSPDTATPLTKI"
     gene            14062..14604
                     /locus_tag="AC1PIV_000301"
     CDS             14062..14604
                     /locus_tag="AC1PIV_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HIP6611355.1"
                     /translation="MVGNNGVGKSTFLKILLGLDRDFAGQIEVKADWAYVPQLQERSS
                     LSGGEQVWKSIQEAFAQRPQLLIMDEPTANLDQEHQEKLIKQIKRYRGSLLVVSHDRH
                     FLNQIASHIWHLEEEKVQVYLGNYEAFVESRRARREGQQESYEAYQKKVAQMKKAQHE
                     RQAKAQKMGKRGSGIEVNQL"
     gene            14767..15516
                     /locus_tag="AC1PIV_000302"
     CDS             14767..15516
                     /locus_tag="AC1PIV_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HIP6611356.1"
                     /translation="MMGSYDSQAKSMAKTAKHLEKRIERLDKVEQPRKETWVKMEAKG
                     ALDTGLHSLFRLQAGQVLMDEVYLFDVPQIGMTFGEKLALVGANGSGKTSFVRKLFRK
                     ELAGYYNPKLKIAYFAQDLINLDEEKTAFENVSCTSLQDRMMILNLLGMLGLSCDKAQ
                     QKVANLSGGERVRLSLAKVLLADANLLILDEPTNFLDMAAIEVLETFLKEYEGSVPLI
                     SHDQQFVETSVHSQWEIVQACLVKKSQENIF"
     gene            15593..17668
                     /gene="pbp2b"
                     /locus_tag="AC1PIV_000303"
     CDS             15593..17668
                     /gene="pbp2b"
                     /locus_tag="AC1PIV_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA];
                     GO_function: GO:0071972 - peptidoglycan L,D-transpeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP2B"
                     /protein_id="HIP6611357.1"
                     /translation="MKKRKNKPLEHDGNFISLRLNILFSIVIFLFLVLILRLADMQII
                     NHDFYSNKLSTASQKIISNGSIRGQIYDAQGKPLVENEIQQVVSFTRPNKMSAQEMKE
                     VANKLLQWVNVSDVTITQRDKADYYLADEEVYRQVVEALPKDKKYDSDGNYLSESTIY
                     SNAVDSIPAEALQYSEQDNKAIELFKQMNGATYFSTVNLVTDTLTSEQVAHIVANESQ
                     LPGISTTNNWQRTILPTSLSSIIGTVTSEQAGLPAEDAEYYLSKGYSSNDRVGTAYLE
                     KQYEEVLQGQREKKQINLDRNGNIESIETIQEGQQGNNIKLTIDLAFQDGVNAILRKY
                     FESELATGSALYSEGVYAVALNPSTGAVLAMSGYSHEKGSSTITEDALGTITSVFTPG
                     SIVKGATISSGWENGVISGNQIQLDEPIYFAGSAPITSWYGAYGSFNIDATEALEYSS
                     NIYMVKIALGLLGQTYSANMYLNDGDTLKNAMTKLRSTFAEYGLGASTGIDLPLESTG
                     FLPDKYTTANFITNAFGQFDNYTPMQMAQYAATIANNGTRISPHLVEGIYGNNAQGGL
                     GELIETVSGKEMNQVNISAEDMSLLRQGFYQVVNGSGRFNTGSAIGRGAAVTISAKTG
                     TAETYTTTASGDVVTAVNTNVVAYAPSDNPQIAVAVVLPNLTNQSSTTTKTITQEIIN
                     LYQSLHPMN"
     gene            17677..18273
                     /gene="recR"
                     /locus_tag="AC1PIV_000304"
     CDS             17677..18273
                     /gene="recR"
                     /locus_tag="AC1PIV_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HIP6611358.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMEDDVVNEFA
                     KNLLAAKRDLSYCSICGNLTDQDPCAICQDSTRDQSTILIVEDSRDVTALENIQEYHG
                     LYHVLHGLISPMNGIGPDDINLKTLLTRLMENEVTEVIVATNATADGEATSMYISRVL
                     KPAGIKVTRLARGLAVGSDIEYADEVTLLRAIENRTEL"
     gene            18378..19424
                     /locus_tag="AC1PIV_000305"
     CDS             18378..19424
                     /locus_tag="AC1PIV_000305"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HIP6611359.1"
                     /translation="MSKETLILLYGGRSAEREVSVLSAESVMRAINYDKFFVKTYFIS
                     QTGDFIKTQEFSQTPSADEKLMTNATIVEEQKIRPSDIYEEKAVVFPVLHGPMGEDGS
                     IQGFLEVLRMPYVGTNILSSSVAMDKITTKRVLESAGISQVPYVAVIEGENIDDKIAE
                     IEGKLTYPVFVKPANMGSSVGISKAEDLAGLRKALDLAFKYDSRVLVEQGVNAREIEV
                     GLLGNADVKTTLPGEVVKDVAFYDYDAKYIDNKITMEIPAKIDESIMDIMRDNAAKAF
                     RAIGGCGLSRCDFFLTEDGDIFLNELNTMPGFTQWSMYPLLWDNMGLAYPDLIEELVR
                     LAKEMFEKRESHLI"
     gene            19512..19892
                     /locus_tag="AC1PIV_000306"
     CDS             19512..19892
                     /locus_tag="AC1PIV_000306"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004601 - peroxidase activity [Evidence
                     IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OsmC family protein"
                     /protein_id="HIP6611360.1"
                     /translation="MYQTTVKGEGLFQALSQGYGESVRTFGVTEKGETPVSLVNIGLA
                     ACITMCVQGYYASQEGNKTMPVQVESRLDNQRFEVLIGIGESVSAQKQKEILAYVEKK
                     CKVKALLREDLQFETSFYVLESVE"
     gene            20021..21382
                     /locus_tag="AC1PIV_000307"
     CDS             20021..21382
                     /locus_tag="AC1PIV_000307"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HIP6611361.1"
                     /translation="MKLTLHEVAQVLGAKNDISLYTDTAFNKVEFDSRLVTTGDLFVP
                     LKGARDGHDFIPVAFENGCVVTLSEVSLDVPHILVEDCLAALQQLAAYYLEKTGVEVI
                     AVTGSNGKTTTKDMIHDVLATTYKTYKTQGNYNNEIGLPYTVLHMPDDTEKLVLEMGQ
                     DHLGDIHLLSEIAKPSLSVITLFGEAHLEFFGSREEIAKGKLQIADGMEPGSKLLIPA
                     DPIADKLLPSHVDLIRFGEQADLQVTSLVESKDSLTFTVNFMDGDIFLPVTGKYNATN
                     AMVASYVGKTLGVPDEAIKSALASLNLTRNRTEWKKAANGADILSDVYNANPTAMRLI
                     LETFTSIPANEGGKKIAVLADMKELGSQSVDLHNQMILSLSPDVLDTVIFYGQDIEGL
                     AQLASQMFPIGKVYFFRKNAEQDQFEDLVKQVRESLGKEDQILFKGSNSMNLGKVVEA
                     IEK"
     gene            21542..22171
                     /locus_tag="AC1PIV_000308"
     CDS             21542..22171
                     /locus_tag="AC1PIV_000308"
                     /inference="COORDINATES: protein motif:HMM:TIGR02206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HIP6611362.1"
                     /translation="MIIWFFMLHLCFRCYQKRWFHIVFWWLQFIQIVSLYTWYIVADS
                     PLSESLPFYHCRLAMLFILWAKPGPLKRYFAYLGLFGSLAAFIHPVFDPFAFPHLTFF
                     TFVIGHYALTVNCMLYLLSDLEGEMLKGKEVVKYTLIMNMLILGVALLTGGNYGFLRQ
                     APLVNTNNLPLNFFLVTCLLCFSILSIQAMLIAYLKKESKQMNSHILKK"
     gene            complement(22202..24538)
                     /locus_tag="AC1PIV_000309"
     CDS             complement(22202..24538)
                     /locus_tag="AC1PIV_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HIP6611363.1"
                     /translation="MNKQIKGLSTKEVQERIQNQQTNHFKTKTSASNWEIFRRNVFTS
                     FNALNFAIFLALLAVQAWSNLFFFGVIVLNAVSGMLTEWRARRMIDKLNLMNKDFIRV
                     VRDSETISIAPEDIVLDDVLLLSAGEQVPSDAIVLEGIAETNEAMLTGESDLIVKNTG
                     AELLSGSYLVSGQIYAKVIHVGAENYANKLMLEAKTHKPIVSRILYNMDKIAKFTGKI
                     IIPFGLALFLEAFFIKILPLKDSVITSSTALLGMLPKGIALLTITSLLTAVIKLGMKN
                     VLVQEMYSVETLARVDVLCLDKTGTITQGKMTVENLLPLTNHYSLDTIQQILATYIQT
                     SEDTNSTAQAIRKEYGDLEHHYKASHIIPFSSDRKWGAMTIENIGHIFLGAPEMLLTQ
                     NPPSVSEAQARGSRVLILALSQQSLLSSQNQLPENIEPLALLEIADPIREDAAETLAY
                     LRSQEVTLKIISGDNPVTVSHIAREAGFADYDSYIDCSKVDDEELIARAETTAIFGRV
                     SPHQKKLLIQTLKAQGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLD
                     SEFRDIPEILFEGRRVVNNISHIAPIFLIKTIYSFLLGLICIASIALGKAEYLLVFPF
                     IQVQMTLIGQFVEGFPPFILTFERNIRPVEKHFLRKSLLLALPNALMVVLSVLIFHLM
                     QVFGYLNLHDMQTLSYYVLGSTGLLAVIRACLPLTKARLALIIYSVFGFFISSHFLHG
                     LIEIHPLNSHTLPIYSGLMLIFIPVFFWISYKQGAFKN"
     gene            24775..26319
                     /locus_tag="AC1PIV_000310"
     CDS             24775..26319
                     /locus_tag="AC1PIV_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HIP6611364.1"
                     /translation="MSLQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGNFAKSDWMDIEKQRGISVTSSVMQFDYAGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRNIPVFTFINKLDRDGREPLDLLQELEEVLG
                     IASYPMNWPIGMGKSFEGLYDLHNKRLELYRGDERFASLDEGDKLFGSNPFYAQVLDD
                     IELLAEAGNEFSEQAILDGDLTPVFFGSALTNFGVQTFLDTFLEFAPEPHGHKTTTGD
                     VIDPLNKDFSGFVFKIQANMDPRHRDRIAFVRVVSGEFERGMAVNLPRTGKGAKLSNV
                     TQFMAESRENVENAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAIQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMAPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            complement(26617..27873)
                     /locus_tag="AC1PIV_000311"
     CDS             complement(26617..27873)
                     /locus_tag="AC1PIV_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HIP6611365.1"
                     /translation="MEQLNLITNFLRIKDKNITITDEYDMGTHLELHGYLDYMAPKCP
                     ECKGQMAKYDYQKASKIPYLETAGYPLLIRLKKRRFKCKECGKMAGAETPLVKKNHQI
                     SVAVSQKIAQLLIENQAMTHIAHRLSISTSSVMRKLNEFKFETDWNTLPEVMSWDEYA
                     FKKGKMSFIAQDFDSLNVIAILDGRTQATIRNHFLRYPRKVRNQVKVITMDMFSPYYQ
                     LAKQLFPNAKIVLDRFHIVQHLGRAMNRVRIQIMNQFDRTSQEYRALKRYWKLIQQDS
                     RKLSDKRFYPPMFRMHLTNKEILEKLLSFSEELRQHYELYQLLLFHFQEKNSDHFFDI
                     VELEIATVNPIFQTVFKTFLKDKDKVLNALELPYSNAKLEATNNLIKVIKRNAFGFRN
                     FENFKKRILIALNIKKERTKFVLSRC"
     gene            complement(28002..28805)
                     /locus_tag="AC1PIV_000312"
     CDS             complement(28002..28805)
                     /locus_tag="AC1PIV_000312"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HIP6611366.1"
                     /translation="MKKILVLALASSILLTACTNNSTANSSSSTASSSSPSSTTTADT
                     TASSQYAKDLAYAINNPKATFPQLSNEIGENEAAIKIKTTEGDITIKLFPEQAPLTVE
                     NFLTHAKEGYYNGTIFHRVIKDFMIQGGDPLGNGTGGESIWAGKDTTIDAGNGFKDEI
                     SAFLYNIRGSLSMANAGAGTNGSQFFINQNTTDMSSQLSSSSYPGKIIDAYKNGGNPN
                     LDGKHTVFGQVIEGMDIVDKIASVETDNSDKPKTDVKIESIEILKDYTF"
     gene            28948..29301
                     /locus_tag="AC1PIV_000313"
     CDS             28948..29301
                     /locus_tag="AC1PIV_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2500 domain-containing protein"
                     /protein_id="HIP6611367.1"
                     /translation="MFENLFDPDGSLVWHTALFYSFSAIILATVCFHIIKNFMEWHHN
                     NRAPKESCKAKLVSKRTHVFGNEVARTNYYVTFEWEGKRQEFRLRSDEYALLAERDVG
                     TLHFQGTRFLGFERL"
     gene            29386..29763
                     /locus_tag="AC1PIV_000314"
     CDS             29386..29763
                     /locus_tag="AC1PIV_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000625774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance/extradiol
                     dioxygenase family protein"
                     /protein_id="HIP6611368.1"
                     /translation="MIQSIGQVMLYVNDIEASAQFWKEKMGFERVEKQVQGPQTSYII
                     APKSDSEVQFVLHDKAEVAEMEPELNLGTPSILMTSVDVAKTYEELVERGVTTNPVMD
                     LGFMKVISFADNDGNYYAIREVK"
     gene            29764..30309
                     /locus_tag="AC1PIV_000315"
     CDS             29764..30309
                     /locus_tag="AC1PIV_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611369.1"
                     /translation="MSLQNRVEEMYKDHEVKPYISPERDLAAWLLEAKPVPKRNMVRL
                     EEGILPGDIILLWRISLGSFESTTPYSKYFEYMYGINGPAHMEQLIADGYAYVESAFD
                     SLDHITSTAKKNILKAEGVTGLSKMKAADLDTALKDNLTEEKLAPYFTVRGYALTEKG
                     RAALDNHPEVLAKHPMKKMYK"
     gene            30466..31455
                     /locus_tag="AC1PIV_000316"
     CDS             30466..31455
                     /locus_tag="AC1PIV_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HIP6611370.1"
                     /translation="MEEQKSITMKDVARVAGVSVGTVSRVINNEPGIKESTLEKVNAA
                     IKELNYIPDVYARGMKKNKTETIALIIPTVWHPFFGEFAYHVEVELSKKNYKLLLCNI
                     SGPKRELDYLTMLQQNKVDGIIAITYSPIEDYLSSNIPFVSIDRTYENKAIPCVSSDN
                     RAGAELAANTLIAKGGRHFAFIGGHNKTINETKKRRLYFEKRILEAGFPCHVLDLEEP
                     YDDFVGQVEEFLINNPQVDAIFTINDFTALDTLAVLEKLRRRVPEDVQVIGYDGIQLA
                     SEKSLALSTIRQPLESMAQEAVACLIDIIEKRERPLQVTLPISYLEGKTTKNF"
     gene            31560..32480
                     /locus_tag="AC1PIV_000317"
     CDS             31560..32480
                     /locus_tag="AC1PIV_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIP6611371.1"
                     /translation="MKTSKLQQASLFDRIKQQKLLLLMLLPGLVLTFIFRYIPMYGVL
                     IAFKDYNPLKGVLGSEWIGFEEFTKFLSSPNFGTLLANTLKLSVYGLLLGFLLPIILA
                     IMLNQLLSDKAKKRIQLVLYAPNFISVVVIVGMIFLFFSVGGPVNSILGMFGIEANFL
                     TDPDFFRPLYILSGIWQGMGWASTLYTATLINVDPALIEAAKLDGANIFQRIWHIDLP
                     ALKPVMVIQFILAAGGIMNVGYEKAFLMQTSLNLTSSEIISTYVYKIGLVSGDYSYST
                     AVGLFNALINIILLIAVNKIVKRINDGQGL"
     gene            32490..33377
                     /locus_tag="AC1PIV_000318"
     CDS             32490..33377
                     /locus_tag="AC1PIV_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HIP6611372.1"
                     /translation="MNTQMYTKFDKRMLVVNKILLAFLVLITVVPMVYILVASFMDPQ
                     ALLSKGISFDPKDWTVEGYQRVFSDKSILRGFFNSLFYSFSFAFVTVSISVMTAYPLS
                     KKDLVGKKWINAFLVFTMFFGGGLVPTYLLVKDLGMLNTVWAIIIPGAVNVWNIILAR
                     TYFQGLPDELVEAAVMDGANEFQIFWKIMIPLAKPIMFVLFLYAFVGQWNSYFDAMIY
                     IKDPDLEPLQLVLRKILIQSEPAKDMIGAQAAMNEMKRIAEMIKYATIVISSLPLIVM
                     YPFFQKYFDKGIMAGSLKG"
     gene            33424..35034
                     /locus_tag="AC1PIV_000319"
     CDS             33424..35034
                     /locus_tag="AC1PIV_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HIP6611373.1"
                     /translation="MKHTFGKTVVTLLASTVLLAACGSKNTASSPDYELKDVQFPLEK
                     SVTLKFMTASSPLAPADSNEKLIFKRLEEETGVHIDWTNYQSDFGEKRNLDIASGDLP
                     DAIHNDGASDVELMNWAKQGVIVPVEDLIDKHMPNLKKILDENPEYRSMITAPDGHIY
                     SFPWIEELGEGKESIHTVNDIAWINKEWLDKLGLDMPKTTDDLIKVLEAFKTQDPNGN
                     GKADEIPMGFINGGGNEDFKILFGAFGVGDNDDHLVVNNDGTVDFTADNEDYKEGVEF
                     MRTLQEKGLLDSEAFEQDWNTYIAKGSENLCGVYFTWDKANITGMNDTYDILPVLAGP
                     DGTKHITRTNGMGFQRDRMVITSANKNLELTAKWIDAQYKPIQSVQNNWGTYGDETQQ
                     NIFELDTATNSLKHLPLEGTAPGELRQKTEVGGPLAILDEYYGTVTTMPDDAKWRLDL
                     MHATYLDYVTNDDIYPRVFMEQEDLDKIAQVEADMNDFIYRKRAEWIVNGGIEEEWDS
                     YLKELESYGLSDWLAIKQKYYDQYKENQ"
     gene            35052..36410
                     /locus_tag="AC1PIV_000320"
     CDS             35052..36410
                     /locus_tag="AC1PIV_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HIP6611374.1"
                     /translation="MKTVVEANQFIQKEKGNVNPIFKPQAHLTPETGWMNDPNGFIYF
                     RGEYHLFYQFNPYESVWGPMHWGHAKSKDLVNWEQLPVDLAPDKAYDKDGCFSGSAIV
                     KDDVLWLMYTGHIVNEDGTVSQVQNMAFSTDGIHFEKIEQNPVATADGLPEEVIANDF
                     RDPKIFEKDGHYYSVVATKHKDNVGCIVLLSSPNLTDWKFESIFLKGEANQGFVWECP
                     DYFEVDGQEYLIISPMRYQKDGNDFININSNIFVTGHVDWDKKVFVAESFKEIDHGHD
                     FYAAQTTEGPEGERVMIAWMHTWGRPLVTNDLGHKWYGQMTLPRLLKQGENGLRQVLP
                     AGILNSFDDIEIGQVIQGPSKLSLKLDDSLDLKLGTDRDYLQFGYDKAKQEVYIDRSH
                     LKIQQVGEEEWSTVRRAVTVQATELEVLVDTNCLEIFINDGQETLTSTFYVEGQIILN
                     AL"
     gene            36536..38905
                     /locus_tag="AC1PIV_000321"
     CDS             36536..38905
                     /locus_tag="AC1PIV_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HIP6611375.1"
                     /translation="MRKTSKKGKATRRPTKAELAQQERVKNITLRVLGLLFIAFAASR
                     LGVFGVTSYNIFRLLFGSLAYLLLVGAFIYLLIPKVLREREGTISGFWLIVIGLLIEF
                     QAYLDWTYQGSDLFGHTLKLALSDLAKFQVTAFLGGGMIGSIFYLPVSFLFANVGSFF
                     IGLLVIAFGIFFVSPWSVYDVADGLAVAKDKLVETQVKRAELRTQKKAEREEKRQQEL
                     ARLEEERLRLEEEEESARALALVDRHVNLETGEILEEEPVQVPIISEYDHLDIEDEFP
                     IMLAEDDQPAQSNSASQDSETNEFEKDETDVQIDFKPKQRLAYKLPSIDLFAPIKAKS
                     QSNEKRIVRQNIKVLEDTFASFGIKVVVERAEIGPSVTKYEVKPAVGVRVNRISNLAD
                     DLALALAAKDVRIEAPIPGKSLVGIEVPNSEVATVPFRELWEQSKTDPDKLLEIPLGK
                     AVNGSVRSFNLARMPHLLVAGSTGSGKSVAVNGIISSILMKAGPDQVKFMMIDPKMVE
                     LSVYNDIPHLLIPVVTNPRKAARALQKVVDEMEKRYELFSQIGVRNLEGYNAKVEEFN
                     SRSEEKQIPLPLIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGIHMILATQRPSV
                     DVISGLIKANVPSRIAFAVSSGTDSRTILDENGAEKLLGRGDMLFKPIDENHPVRLQG
                     SFISDDDVEAIVGFIKDQADADYDESFDPGEVAEGDGDAGFGDAGGDPLFNEARALVV
                     ETQKASASMIQRRLSVGFNRATRLMEELEAAGVIGPAEGTKPRKVLETQ"
     gene            38905..39291
                     /gene="gloA2"
                     /locus_tag="AC1PIV_000322"
     CDS             38905..39291
                     /gene="gloA2"
                     /locus_tag="AC1PIV_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002931159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMU1112c/YaeR family gloxylase I-like
                     metalloprotein"
                     /protein_id="HIP6611376.1"
                     /translation="MKFDAVHHIAIIGSDYGKTREFYVEKLGFEQVDEHIRPEKNDIL
                     FNVKKGNLILEIFIKPDAPMRPAMPNPEHTGLRHLAFQVADVEACLEEFDRLDIRHEV
                     LRTDDFDGKKMAFFFDPDGLPLEIHE"
     gene            complement(39659..40027)
                     /locus_tag="AC1PIV_000323"
     CDS             complement(39659..40027)
                     /locus_tag="AC1PIV_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HIP6611377.1"
                     /translation="MFESIIFLKIVAFLFIFLTLAISIIAVKFFRLQNRGWNFADIAF
                     PLYAIEFYLISDKAYYNSLLPQLVLALSLLAIGLCGFFLLKKKNFLYRRFFKVFWRAS
                     FILTFLMYLALVIAVFTLKS"
     gene            40182..40607
                     /gene="rplK"
                     /locus_tag="AC1PIV_000324"
     CDS             40182..40607
                     /gene="rplK"
                     /locus_tag="AC1PIV_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HIP6611378.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFITKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAASLEAAMRMIEGTARSMGFTVTD"
     gene            40648..41337
                     /gene="rplA"
                     /locus_tag="AC1PIV_000325"
     CDS             40648..41337
                     /gene="rplA"
                     /locus_tag="AC1PIV_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HIP6611379.1"
                     /translation="MAKKSKNLRAALEKIDSTKLYSVEEAVALAKETNFAKFDASVEV
                     AYNLNIDVRKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINGGWLDFDVVIATPDMMAVVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADKAGIVQALIGKVSFDADKLVENFKAFHDVMAKAKPATAKGTYMTSVSITTTQ
                     GVGIKVDPNSL"
     gene            41444..41734
                     /locus_tag="AC1PIV_000326"
     CDS             41444..41734
                     /locus_tag="AC1PIV_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611380.1"
                     /translation="MKVAEKEELYKYLSAAYNLPQEAFSEALREKILEVAGQLDKEEN
                     LYILAGHLSRFINAELTALTCRAPKELVQLAHYLQEVQNHYRYASLFPGKVK"
     gene            41743..42531
                     /gene="yghU"
                     /locus_tag="AC1PIV_000327"
     CDS             41743..42531
                     /gene="yghU"
                     /locus_tag="AC1PIV_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HIP6611381.1"
                     /translation="MTEYTKPLVWKWEDENDNRSGNRPTAGSRFEQDLPRGEKSFQVY
                     SLGTPNGIKVAIMLEELKELGISEADYDLFLINIGQGDQFGSDFVAINPNSKIPAMVD
                     YSEQEPISVFESANILLYLAEKFEAFLPKAWAERTEVLNWLFWQTGAAPFVGGGFGHF
                     FHYAPTAQEYPINRYTMETKRQLDLLDQLLATREYIAGNTYTIADIAIWSWYGRLVQG
                     ELYPGSAEFLDVDSYKHLKTWVDKIAQLPAVQRGLTVKYHSIDN"
BASE COUNT        12511 a         8133 c         9543 g        12432 t
ORIGIN      
        1 gcgagggctt tgtggttgat tttaagtctg tcacactctg taagttgtgc gagatgttga
       61 agcgaatcta gagaagcagt actggacttg ttctcatcct ttagaactgt atcagttagg
      121 tgattattat aatttacgtt tacgtgtaaa taacgcaatt gcaagcccga taataccact
      181 tgtcaataac cataaacttc ctttctcacc agttactggt aagatttgct tagcagtttc
      241 ggttttaaat gttgaagtct cctgcttgtc tgttttttca gttgttggtt tagtgtttga
      301 attttcttcg actgtaccat tttggttgtt ctcattaaca ggtatctgtt ttttagaggt
      361 ttcgatattt tccttctctt tattagccat ttgcttttca ggtgttacgg cattgtcctt
      421 ctcattaaca ggcatctgtt tttcagaggt ttcaacctta tcgttctctt tattagccat
      481 ttgttcttga ggtgttacga ccatgtcgtt cacaatgctt ggcatctgtt tttcagagat
      541 tacaacctta tcgttctctt tattagccat ttgttcttga ggtgttacga ccatgtcgtt
      601 cacaatgctt ggcatttgtt tttcagaggt ttcaatatta tccttctctt tattagtcat
      661 ttgcttttca ggtgttacgg cattttcgtt cacaacactc ggcatctgtt tttcagaggt
      721 ttcaatatta tcgttctctt tattagtcat ttgcttttca ggtgttacgg cattttcgtt
      781 cacaacactc ggcatttgtt tttcagagat tacaacctta tcgttctctt tattagtcat
      841 ttgcttttca ggtgttacga ccatgtcgtt cacaatgctt ggcatctgtt tttcagaggc
      901 ttcaatatta tccttctctt cattagctat ttgctcttta gggggttcga tatttccctt
      961 ctctttaccg gtcattgctt ccttagagac ttcattatca gtaataacgc tatccgtggt
     1021 tggcgctatt aacttcccag gattcaaaat attctcgaag atttgatcgc tattttcata
     1081 agtcactgtt gagactagtt gtccgtgatt gttatctttc acagtaacag tggccttaat
     1141 atctgatttg tcatagataa tatcgccaag tccaccatca acttctgaaa cagtgtaggt
     1201 ataggttccc tcttttgtaa atgttagggc actaaagttt acagaaccat ctgcttgatt
     1261 gcttaccttt tcgatttcat cgcctttttc attttttaaa acaaattcga attcaccggt
     1321 gtttaaggta cgtccctcga ggactttttt tatcgaaaga ctagcagcag ctggagcagg
     1381 tgtatagaaa ttgttaaaga cattgtcatt atcaataaat tcgatcattg cctgtaattg
     1441 cccgtttcga tcttctacag ttatttttgc tacaatatat ttcgaatcat actcaatacc
     1501 accaagctca tcttttactt ctgaaattgt ataccagtat ttgccaggct tatcgaatga
     1561 tagattttta aatctaactt gaccctcttt tgtattttga gctgtatcaa ggacagggag
     1621 ttcctcgcca ttcgcttctc taagctcaaa tttaaattca ttttctagaa gctcacgacc
     1681 aaatagtcgt actactgctg gtattttgac attaaccgcc tttgaagtag cctgtccccc
     1741 atcaggttgt tttgcgctga tgatggtatt ttttacttct tgtgccgata cattattcac
     1801 tagagcaaca gttccaaata atactattcc tggtattagg agcgatgttc tccatttctt
     1861 agtattcatt atcctttttt cctttctcaa agcatgattt atgtagctaa tctgtgtcgt
     1921 tataacatgc aaattttaca tctaaagtcc tcaataaaat ttgaacactt agtgccagaa
     1981 tgtgcaccat tcgtaaatta taacatcttc taaaaaacat tcaagctgtc cttctgcttt
     2041 taaaatctgt tttatctgtt ttttatgtaa tcatatattt gggattatat tctttagtat
     2101 tggctttaat tgatacaaaa ttcgtgtaga atacagttta aaatatgaaa aaatgtaaaa
     2161 aagggctata atggtattat gaaagtacta ttgtatttag aaggtaaaac tgttttagag
     2221 aaatcaggaa ttggccgggc acttcaacac cagatggaag cgctagatat ggcaggcatt
     2281 ccttatacaa cagacctgct gggagattac gatgtcattc atatcaatac ctatggtcca
     2341 cgctcctggt tattgctaca tgcagccaaa cggagtggaa aaaaggtaat catgcatgga
     2401 cattccacga aggaagattt tcaaaattcc tttatcggtt cgaataccct agctcctttt
     2461 gtagggaaat atctagcaag catgtaccaa aaggcagact ttgtcatcac tccttcagag
     2521 tattcaaaaa aactcatcca gtcttacggt gtgacaacgc caattatagc cgtttcgaat
     2581 ggtattgatt tagataaata taagaaggat gaacgcaagg aagcaatctt tcgagagcat
     2641 tttaaaattg aagaagggca gccggttgtt gtctgtgcag gactctactt tcgacgtaaa
     2701 ggaattgaag actttgtcaa ggtagccgaa aagatgccgc atgtccgctt catttggctc
     2761 ggttcaatca ataagtggct gattccgtca tatattagaa aaattgttga gggagatcat
     2821 ccagcgaatg tcgagtttcc aggttatttt aaaggtgctg tttttcaagg tgcaatgagc
     2881 ggagcgaatg cctttttctt cccatcgtat gaggaaacag aagggattgt tgttctggaa
     2941 gctcttgcta gtcatcagca tgttgttcta agagatattc cagtttacga tggttggatt
     3001 gacgaaaacg ttgccgaatt gggacataca gtggatgatt ttgtcgattc tattcagaaa
     3061 atcttagaca agcaggttga taaacgtgag gcgggctacc aggttgcggt tagtcgctcg
     3121 attgacaatg tttcccacca attggtggat gcctatcgac aagtattgga gatgtaaatg
     3181 cggattggat tgtttacgga tacctatttt ccacaggttt caggagtcgc gacttcgatt
     3241 cggactctta agacagagtt ggagaaattg ggacatacgg tatttatttt tacgacgaca
     3301 gatgaggatg tgaatcgcta cgaagattgg gacattatcc gaattcctag cgtacctttt
     3361 tttgccttta aagatcgtcg agtggcctac gcaggtttta cagatgcctt aaaaattgca
     3421 agtcgctata aactagatat tattcatact catacagaat tttctttggg gattttgggg
     3481 aaaatgattg ccaaggaact agatattccg gtggtacata cttatcacac ccagtatgaa
     3541 gactacgtac actatattgc caaggggagg attattcgtc ccgggatggt taaatattta
     3601 gtacgggcat ttttaaaaga tttggatggg gtaatttgtc ctagtgagat cgttgaagat
     3661 cttttaatga gttacaatgt tccgatttct aaacgagtaa ttccgacagg aattgacttg
     3721 gcaaagtttg atagaccaga aattggcaag gatgaaacag atgagttgcg ggaacagcta
     3781 ggaattgcta gtgatgaaac gatgttgtta agtctgtcta ggatttctca cgagaagaat
     3841 atccaagcaa tcgttcaggc aatgccaaaa attttgctgg aaaatccaaa ggtgaagttg
     3901 gtcattgtcg gaggtggacc ttatacagat gatcttcagg aaatgatagc ggagcttaat
     3961 ctagatgaac atgtccagtt gacgggaatg attgcaccaa gtgatacagc actttattat
     4021 aaagctgcgg atttctttat ttctgcttcg accagtgaaa cacagggact aactttctta
     4081 gaaagtttag cttctggaac tcctattttg gcacatagca atccctactt aaaaaacgtt
     4141 ataacagata agatgtttgg gacgctcttc attcgagaac aggagttggc agatgccgtc
     4201 gttgaggcaa ttgttgctac accaccaatg aatccgtatg tgcttgataa gaagctctat
     4261 gagatttctt ctacgaattt tggacgtaag gtttttgaat attatctaga tttgaagatt
     4321 tcgtatgatt ttagaaaaga acatactaat caagatagcg tagcagaagc tttgataaaa
     4381 gaggctattt acctaccgca aaaagtagta gttaaatcaa cagacacgac agcaaaaata
     4441 ttgaaaaaat cagtcgaaca agtaaaatca atccggaatt tctttgaata atttggaggt
     4501 ttcaaatgga aaagcttcgg aaagagagtt ggaagaatct ggttttggca actcttatta
     4561 ttctgtccat gtatgcaggt atttatctga ttgcctttca tctgattagt gatactatgc
     4621 tttctaagga actggtggtc ggaaatatat tgctctatac tcccattgtg ctattcttaa
     4681 ctggtcttct ttatggattt tttcacggtt tttctcctag ccttcttgtc ttggttttac
     4741 tactttatcc tgtaaccatc tttttcttta aggaatggat tattctctat cagattgtct
     4801 acaccttatg tgctctgatt ggaaatggga taggagctct gctattttct ctaagaaaga
     4861 aaatgaggaa aaatccttga aaaatcagga aatcctgtta taatagcttt tagagactta
     4921 tcaattctag gaaatctttg agagagtgtg cggtgggtgc aagcacatag aggataggat
     4981 tgacactact cggtatgatt ttatgcaaac ataaaagggt ggttccctta tcgccaatct
     5041 gaggtagtca ggcttttttg cgtgactgcg aatgaaggtg gaaccacgtt acgacgtcct
     5101 tttacgaggg cgtcgtattt tcttttggag gaggaatgat gctacctgat gacttattaa
     5161 gacggtgtca agatgtgcgt cgtgcttata gagagttgga aatcaagcac catgacaaag
     5221 agtggtctat tgatgaggac ctcttggctt tgaccaatga tattggcaac atgaaccgac
     5281 tgattatgac caagcagggt cgttactatg acgaaacgcc ttataccttg gagcataaaa
     5341 tggctgaaaa tatctggtgg ttgatcgaat tagccgaccg cctggatatt gatattcaaa
     5401 aagaaatgga aaccttttta gctcaaaaag aagagttatt ggggattaaa aataaataaa
     5461 aaggagataa acatgattaa aattactttc ccagatggtg ctgttcgcga gtaccaggct
     5521 ggtgtgacta cttttgaaat tgcagagagc atcagcaagt ctttggcaaa aaaggctctt
     5581 gctggtaagt tcaatggtaa attgattgac actactcgtg ccattgacga ggacggcacg
     5641 cttgaaattg taatgcctga ccacgacgat gccttggaca tcttgcgtca ctcagcagct
     5701 catttgtttg cccaagcggc tcgtcgcctt ttcccagaca ttaagttggg cgttggtcca
     5761 gccattcagg acggtttcta ctatgatacg gacaatgcgg ctggtcagat ttcaaatgaa
     5821 gatttgccac gcattcagga agaaatgatg aagattgtca aggaaaactt cccttctgaa
     5881 cgtcgtgaag tgactaagga agaagctctt gaaatcttca aaaacgatcc ttacaagttg
     5941 gaattgattc acgagcactc tgatgacgag ggcggtttga ccatctatac gcagggtgaa
     6001 tacgttgacc tctgtcgtgg tccacacgtt ccgtcaacgg gtcgtatcca gatttttgaa
     6061 ttgctcaatg tggctggtgc ttactggcgt ggtaagagtg aaaatccaat gatgcaacgt
     6121 gtttatggta cagcttggtt tgacaagaaa gacctcaagg cctaccttca aatgcgtgaa
     6181 gaggctaaag agcgtgacca ccgtaaactt ggtaaggaat tggatctctt catgatcagc
     6241 caagaagttg gtcaaggttt gccattctgg ttgccaaatg gggcgactat ccgtcgtacc
     6301 ttggagcgtt acatcacaga caaggaattg gcttctggtt accagcacgt ttacacacca
     6361 ccattggctt ctgttgaact ctataagact tcaggtcact gggagcatta ctcagaagat
     6421 atgttcccaa ctatggacat gggcgacggt gaagagtttg ttcttcgtcc gatgaactgt
     6481 ccacaccaca ttcaagttta caaaaaccat gtgcgttctt accgtgagtt gccagtgcgt
     6541 atcgctgagc ttggtatgat gcaccgctat gaaaaatctg gtgcattgac tggtttgcaa
     6601 cgggtacgtg agatgaccct caacgacggt catatctttg tgacacctga acaaatccaa
     6661 gaagagttca aaaaagctct ccagttgatt attgatgtgt acgcagattt caacctcaac
     6721 gactaccgtt tccgcctgtc ttatcgtgac ccagaggaca aagagaagta ctatgacaac
     6781 gatgagatgt gggaaaatgc ccagcggatg ttgaaaggtg ccatggatga aatgggcgtg
     6841 gactactttg aagcagaggg tgaagcagcc ttctacggtc cgaaattgga tattcaggtg
     6901 aaaactgccc ttggtaacga ggaaaccctg tcaaccattc agttggactt cctcttgcca
     6961 gaacgctttg gcttgaccta tatcggtgct gacggtgagg agcaccgccc agttatgatt
     7021 caccgtggtg ttatctcgac tatggaacgt ttcactgcta tcttgattga aacctacaag
     7081 ggtgccttcc caacttggtt ggctccaaca caagtgacca tgattccaat ctctgtggaa
     7141 gctcacttgg actacgcttg gaaggttgcc aaagaattgc aagaccgtgg cgttcgagta
     7201 cacgtggatg aacgcaacga gaagatgcaa tacaagatcc gtcagagcca aaccagcaag
     7261 attccatacc aactcatcgt gggtgacaag gaaatggaag acaatgctgt caacgttcgt
     7321 cgctacggaa gtaaggcaac acaaactcag tctgtatcag aatttgtgga ccatatccta
     7381 gcagatattg cccgcaagtc acgtccagct gaagcagctg aataaataaa gcaagaagtc
     7441 cgaaagggct tcttttttga cagcaaaaac tcccaaccga ttggctggga gaaatttcat
     7501 tctatactgc tcgcccaaga cttagccaca taacgtgaca ggcttgaaat agcaaagttg
     7561 atactgaagt aaatcagggc aaccataatg tagagagcaa agacttgctc cgcctcaaag
     7621 tagcgtccca tgaggatttg actcgaaccg aagagttctt gcaaagcgat aacggagtat
     7681 aggaaactgg tatccttgat aaccgtcaca atctgagaga tgatggcggg cagcatcttg
     7741 cgaatggcct gtggcatgat gatatagacc atgatttgca ctggggtaaa accctgtgac
     7801 aaaccagctt cggtctggcc cggtccgatg gcgttgagac caccacggat aatctcggcc
     7861 atggctgccg tggtaaaaat agtaaaagca gtaataccag caggcgttga cttcatttgg
     7921 aagactaaga agacggtgaa aatccacagc aagtttggta cattacgcac aaattcgata
     7981 tagatggttg caatccactt gaaaattgga tttttcccat tgcgcatgat ggcgagaatc
     8041 attccgaaaa gaatggacag gattaccgaa atgcttgaga tataaagggt taacttcaat
     8101 ccgctccaca agagttggaa ggttgaaggt ttgagtaatt ctaaaacata attcatcgtt
     8161 caacctcctt ttagtgtgaa aaggctgact tattcttttc ttcaatgcga cgtccccagc
     8221 ttgcgacggg gaagcacatg atgaagtaaa ggaaagcagc accagcaaag gctgggatgt
     8281 agttggcatt catggcagac caagattttg tcataaacat aatatcagct ccagagataa
     8341 tggcaacagt agccgtattc ttaattaagt ttactacttg gttggtcaaa ggtggaagaa
     8401 tggtcggaat ggcctgtggt aaaatgatga ttcgcatggt ttcagactga gtaaatcctt
     8461 gtgaaagtgc ggcttcagtt tgcccagtag gcacagcctc aatccctgca cgaatgacct
     8521 ctgcgatata agcaccgtga tagagtccga cgcagataac agctgtccag tagatggatg
     8581 gcatgagaac ataatttgaa atcagtggaa gtccataata aacaatcatg aactgaacca
     8641 aaagcggcgt gttctgatag tattcaacat agacacgtgc gatgattttt aaaactttat
     8701 ttttacttga agagagacta ccaaagacaa ttcctaaaaa catggccatg ataaaggctc
     8761 cgacagaaat ggctaaggta aagagaaaac cttggaaaaa gattggaaaa tctttgaaat
     8821 aactgaccca attctcccaa gcgtaaggac tagttgttaa aactgtcata ttgtttcacc
     8881 tttctattcg tcagtttctg tgactggttt gagaccattg gcatcataga tgctttgtag
     8941 gctaccatcg gcagtccatt tttctacgag actatttaag tagttgttaa ggtctttgtt
     9001 agataattta gtaacaattc catagtcaga agctgagaag ctaaagtcca tgagttcaga
     9061 tttcgaactg atatacccag caaggataga ttggtctaca gaaaatgcgt ctgtacggtg
     9121 agcacgtagc gagacagaga gttctggata agaaccaagc tctgcaaaat tgacagtgat
     9181 accgtatttg tctgctagtt cagagatgag ggtacgtgta atggaaccct gagctacacc
     9241 gattgtcttt ccatccaggt cggtgaatgt cttaattcca ctatccttat tgaccaagaa
     9301 gccaacggca tctgtgtaat aaggagttgt gaaattgtag agcaacttac gttcctcagt
     9361 gatggtaaaa ggctatgacc atatccactt gactgttatc aagaagtggt cctcgggttt
     9421 gcgctgtaac gggagtaaat tcgatatcta cacctaattc gtctgcaatt ttgcgagcaa
     9481 tatcaatctc cattccctcg aattcaccag tatcagggtt cttgtagcca aagtttggga
     9541 cgtcctgttt cactccgacg cggagcacgc ctctatcgat gatagcttga acttgatcac
     9601 tattagtaat ggatgcgggt gtttctgttt gagctactgg ttgttttgcg aaaacgagaa
     9661 gaataagtcc aaagaccaat aatctaattg caaagaaaat gttgattttt ttcttatcca
     9721 tagacttcct cctagagttt tactttgtca gattcgtggt tgataatctt actgaggaat
     9781 tgttgggcac gaggctctgt cggattgtca aagaagccat tcacatctgt tgtatcaact
     9841 aaaacttctc cctcagccat gaagatgatg cgatcagcta cttcacgggc aaagcccatt
     9901 tcgtgtgtta cgacaatcat gttcatcccg tcacgtgcca atttttgcat aactgcaagt
     9961 acatctccga tagtttctgg gtccaaggca gatgttggtt catcgaagag tagaagctca
    10021 ggtttcatag ctaagccgcg agcgatggca acacgttgtt tttggcctcc ggatagcata
    10081 gcagggtagg aatccttccg atcccagagg ttaacaaatt caagatactt ttgagcggtt
    10141 ttttcagctg tagccttatt gattcccaaa accttaatcg gtgccaaggt aacattttct
    10201 aacacggttt tgtgtgggta aaggttgaaa tgctggaaaa ccatgccaac ttctttgcga
    10261 agtgatacga gctctttgat agaagtagag gaaatatcat gtccattgac gatgagcgtt
    10321 ccttcatcaa ttgcctctaa accgttaatc gtgcgaatga gagtagattt tccggatccg
    10381 gaaggtccaa ggagaacgac aacctgtcca ggttcgaatt ccaagttgat attgcgtagg
    10441 gcgtggtagt caccatagta tttattgaca tctttaaatt ctactaaagc cataaaattc
    10501 tccttgcata ctgtttttta ggtattccca tcttagcatt gcctatatac aatgtcaagt
    10561 aaattctgac aatttaatgt gttgtatgtt ataaaatgtg acatcaccgt gtcagatggt
    10621 tttgaaatat gaatttttta ggtaagtctg atataataga agaaataaag caaaggtaag
    10681 attctaatga aaaaaatatt aattgtagat gatgaaaaac caatctcaga tattattaag
    10741 tttaatatga cgcgtgaggg atatgaagtt gtgacagctt tcgatggacg tgaagccttg
    10801 gaagtatttg aggctgagtt tcctgacatt gtcattttgg acttgatgtt gccagaattg
    10861 gacggactag aggttgctcg aacgattcgt aagaccagca atgttccaat cttgatgtta
    10921 tctgctaaag atagcgaatt tgataaggtt atcgggcttg aaataggggc ggatgattat
    10981 gtgaccaagc ccttctctaa tcgcgaatta caggcgcgtg ttaaggctct tcttcgtcgt
    11041 agtgaattgg cagagacgca gacaaatatt gagtcaacag gaactccaga gttggtgatt
    11101 ggcgatttgg tcattctgcc tgatgcgttt gttgctaaga agcatggtaa agagctggag
    11161 ctgacccatc gtgagtttga attgctccac catctggcca aacacttagg tcaggttatg
    11221 actcgagaac atctattgga aacagtttgg ggttatgatt actttggtga tgtccgcacg
    11281 gtggatgtaa cgattcgtcg tctgcgtgag aaaattgaag atacaccaag cagaccagaa
    11341 tacattctta ctcgtcgcgg agtgggatat tttataaaag gaaatgatta atcaattacg
    11401 ttatttaatg accacggcag aattttggtt tgttgtcatt ttgattggct ttctaattgc
    11461 tctgacggtc cttttgattg aaaactattg ggataataag caaattaaac aactcaatca
    11521 aaaagtcaat gccttaattg aggggaatta tgcagatctg ttagacatga ggggaagtcc
    11581 tgaaatcaca gacatggcta attccctcaa tgatttgtcc gaggtcatcc gcttaactca
    11641 tgataattta gaacaagaaa agacacgtct gacgtccatc ctgtcctata tgagtgacgg
    11701 tgttattgct acagaccgta tcggacggat catcatgatt aacgatatgg cccagaaaca
    11761 gttggggtta tctaacccaa agcaggagca gtatcacctg ctagaggttt tagatttatc
    11821 agaccgttat acattgagag atttgttggc tcagacacct gagattgtga ttgatcacac
    11881 caatgaaaac gaagaatttc tgactttacg cgctaatttt gcaacgattc gtagtgagag
    11941 tggtctgatt tctggcctgg ttgtcgtctt gcatgatatg accgagcagg ccaaggaaga
    12001 acgggaacgt aggctgtttg tgtcaaatgt gagtcatgaa ttgcgtacgc cattgacttc
    12061 cgttaaatcc tatctagagg ctctggatga gggagcgctg acggagtctg tggcgccgag
    12121 ttttgttaag gtatccttag atgagaccaa ccgcatgatg cggatgatta cagatctcct
    12181 tagcttatcg cgcattgata atcaagttgg tcagatagat gtcgaactga taaactttac
    12241 tgcttttgtg acctttattc ttaaccgttt tgaccaaatg aaaaatgctg attcagataa
    12301 ggtctatacg attgttcgtg actatcaaat cagtcctatt tgggttgaga ttgatacaga
    12361 taagatgact caggttttag ataatatctt aaataatgcc attaaatatt cgccagacgg
    12421 cgggacaatt accttcagca tgaagaccac agatagccag ttgattgtat ccgtatcaga
    12481 cgaaggtctg gggattccga aagcagattt acctagaatt tttgaccgat tttatcgcgt
    12541 agacaaggca cgatctcgtg cccaaggtgg tacaggtctt ggtttagcta ttgcaaaaga
    12601 aatcgtaaaa caacataagg gctttatctg ggctaaaagc gaatatggtc atggctcaac
    12661 gtttacaatt gtcttgccgt atagcaagga catcgcacta gatgagtggg atgattcaga
    12721 tgaggaagaa taggagaata tgatcggaaa aggttttaat tatagtattt tagcttcggg
    12781 gtccagcggg aattgttttt acctagaaac agataaaaag aaaatcttag tggatgctgg
    12841 cttatcaggg aaaaagatta ccagtctttt ggcggaaatt gatcgaaagc ctgaggatat
    12901 tgatgctatc ctggtaacgc atgaacatag cgatcacatc catggtatcg gtgttttagc
    12961 acgtaagtat ggcatggaca tttatgccaa tgaattgacc tggcaggcta tggagagcaa
    13021 attgggcaag attgatgtgg ctcaaaaaca tatcttcgaa ttgggtgcta tgaagacttt
    13081 tggcgaccta gatattgagt catttggagt tagccatgat gctgcatgcc cgcaatttta
    13141 ccgttttatg aaggatgaca aatcctttgt tatgttgacg gatacaggct atgtcagtga
    13201 ccgcatggtt ggaattgtag aaaatgccga tgcttatttg attgaatcga accatgatat
    13261 tgaaattttg cgcgcaggtt catattcatg gaatttgaag caacggattt tgtcagataa
    13321 gggccatctt tgtaatgaag atggagctga cgccatgatt cgctcgttgg gaaatcggac
    13381 caaaaagatt tacctagggc atttgtcaaa ggaaaacaat atcaaggaat tggctcacat
    13441 gaccatggtt aatcagttgg cgcaggctga tttaggagtt ggagtggatt tccaagtcta
    13501 tgacacatcg ccagatacag cgactccctt gaccaagatt tgacaattga tacaaactaa
    13561 gttatactga aattactaat tatacgaggt gaagttacat gaataattaa gctacttatt
    13621 agttgctctt aaaacttgtg gtgaggttac attaactgac tatacaaggg ataagactgc
    13681 tcataagggc ttactattcg tgtgactttt cccataggga atggtcatgt tttgcatggc
    13741 ttttttctgt gtccattttg cagaattggg gccctttttg tgaagaaaag aggtctatat
    13801 ggaagtaata aaatgtattc gattagagaa ggaatttgcg ggacgtagag gctgggcaaa
    13861 aagcttaacc tcgcttctca gggttcgtgt caacatctca gcgcagtggt tgattggcag
    13921 atttgttcgt gcttcacaca cactccaaat ctgacctaat caactgtgcg ggggcgggaa
    13981 gacgaactct ttttatcttg gtcgagttct ttcctgctcc caagcagttg agccttcaag
    14041 ctagctggtc aaaaggttgg tttggttgga aataacggag ttggcaagtc tacttttttg
    14101 aaaatcttac taggactgga tagggatttt gccggtcaga ttgaggtaaa agcagactgg
    14161 gcctatgtac cccagttaca ggaaaggagc tcgctttcag gtggggaaca ggtttggaag
    14221 tctattcaag aggcttttgc ccaaagacca cagttgttaa tcatggatga accgactgcc
    14281 aatctggatc aagaacacca ggaaaagcta atcaaacaaa tcaaacgcta tcgaggtagt
    14341 ctactagttg ttagtcatga tcggcatttt ctcaatcaaa tagccagtca catttggcat
    14401 ttagaagaag aaaaggttca ggtttatcta ggaaattacg aggcgtttgt agaaagtcgc
    14461 cgggctaggc gagaaggaca gcaggagtct tatgaagcct atcagaaaaa agttgcccaa
    14521 atgaaaaaag cccaacatga acgtcaagcc aaggctcaga agatggggaa gagagggagt
    14581 gggatagaag tcaaccaatt ataaaaactt cgtcatccca cccccgcaca gttgattagg
    14641 tcagatttgg agtgtaagaa acgaacaaat ctgccaatca accactgcgc tgagatgttg
    14701 acgcgaactt tgagaagtga atgtggacat ttattctaaa tatcgtctga gtggaaagtc
    14761 agtgccatga tggggtccta tgatagtcaa gccaagtcta tggccaagac tgccaagcat
    14821 ttggaaaaac ggatagagcg tttggacaag gttgaacaac ctagaaagga aacgtgggta
    14881 aagatggaag cgaaaggtgc cttggatacg ggtcttcaca gtctctttcg cttgcaggct
    14941 ggtcaagttt tgatggatga agtgtatcta tttgatgtcc ctcagatagg gatgacgttt
    15001 ggagagaagt tagccttagt gggggcgaat ggttctggaa agactagttt tgtccgaaaa
    15061 ttatttagga aagaattagc aggctattat aatcctaagt taaaaattgc ttattttgca
    15121 caggatttga taaaccttga tgaagaaaag actgcttttg aaaatgttag ttgtacctct
    15181 cttcaagata ggatgatgat tctcaattta ttaggtatgt taggactttc ttgcgataag
    15241 gctcagcaga aggtagcaaa tctgtctggt ggtgagcgtg ttcgtctctc cttagctaag
    15301 gtattgttgg cggatgcaaa tcttttgata ctagatgaac cgacaaattt tctagatatg
    15361 gcagctattg aggttttgga aacattcttg aaagaatatg aaggaagtgt ccccttgatt
    15421 tcccatgatc aacagtttgt ggaaacatct gttcacagtc aatgggagat agtgcaagct
    15481 tgtctcgtga agaaatcaca agaaaatatt ttctgaaaag gaggctctgt ctaaaaaata
    15541 ttttttgcct gtggtataat aagaaggata tttctagaat gaggtctttg aagtgaaaaa
    15601 aagaaagaac aagcctttgg aacatgatgg aaattttatt tcccttcgtt taaatatttt
    15661 attttctatc gtgattttcc ttttcctagt tttgatattg cgtctggcag atatgcagat
    15721 catcaatcat gatttttata gtaataagct gtctactgcc agtcagaaaa tcatcagcaa
    15781 tggctctatt cgcgggcaga tttacgatgc gcagggaaaa cctttggttg aaaacgagat
    15841 tcagcaggtc gtctccttca cacgtcccaa caagatgtct gctcaggaaa tgaaagaagt
    15901 agctaataaa ctcttgcagt gggtcaatgt ttcagacgta acaattactc aacgtgataa
    15961 ggctgattat tatttggcag atgaagaggt ttatcgtcag gtagtcgagg ccttgccaaa
    16021 agataaaaaa tacgattccg atggtaacta cttgagcgaa tcaacaattt attctaatgc
    16081 agttgatagt atccctgccg aagcattaca atattctgag caagacaata aagcgattga
    16141 actcttcaag cagatgaatg gagctactta cttctctact gttaatttgg taacggatac
    16201 tctgacttct gaacaggttg ctcatatcgt agccaatgaa agtcaacttc caggcatttc
    16261 aacgaccaat aactggcaac ggacgatttt accaacttcc ctcagctcca ttatcggtac
    16321 agtaacgagt gaacaggctg gtttgcctgc agaagatgca gaatactatc tatccaaggg
    16381 ctactcttca aatgaccgtg tgggaactgc ctacctcgag aaacaatatg aagaagtctt
    16441 gcaaggtcaa cgtgagaaaa aacaaataaa cctagataga aatggaaata tcgaaagtat
    16501 tgagacaatc caagaaggac agcagggaaa taatattaaa ctgactattg atttagcctt
    16561 tcaagatggg gtcaatgcta ttttgagaaa atactttgaa agtgagctag ctactggtag
    16621 tgcgctttac tcggaaggtg tttatgcagt tgcattaaat ccttctacag gtgcagtact
    16681 tgctatgtca ggatatagtc atgaaaaagg ctcaagtact attacggagg atgctcttgg
    16741 tacgattaca agtgtcttta caccaggttc catcgtcaaa ggagcgacaa tcagctctgg
    16801 ttgggaaaat ggagttatca gtggtaatca gattcaatta gatgaaccaa tctattttgc
    16861 aggttcagca ccaattacat cttggtatgg ggcctatggt agttttaata ttgatgcgac
    16921 agaggctctg gaatattctt ctaacatcta tatggttaag attgctttgg gactactcgg
    16981 tcagacctac tcagctaaca tgtatttgaa tgatggtgat acattgaaaa acgccatgac
    17041 taagcttcgt tcgacttttg cagaatatgg tcttggtgct tctacaggta ttgaccttcc
    17101 actcgaatct acaggatttt taccagataa gtatacgaca gccaacttta ttaccaacgc
    17161 ttttggacag tttgataact atacaccgat gcagatggca cagtatgcag cgaccattgc
    17221 gaataacggg acacggattt ctccacacct cgttgaggga atttatggga ataatgccca
    17281 aggtggtttg ggggaattaa ttgaaaccgt atctggtaag gagatgaatc aggttaatat
    17341 ttccgctgag gatatgtctc ttcttcgtca aggtttctac caagttgtca atggtagtgg
    17401 gcgctttaat acaggtagtg ctatcggtcg tggtgcggcc gtgaccatca gtgccaagac
    17461 tggtacagcc gaaacctaca caacgacagc ttctggtgat gtggttactg cggtcaatac
    17521 caacgttgtt gcttatgcgc ctagtgataa tcctcaaatt gcggtagcag ttgtcctacc
    17581 aaacttgacc aatcaaagtt caacaactac taagacaatt actcaagaaa ttatcaatct
    17641 atatcaatca cttcacccaa tgaattaagg aggcttatgc tttaccctac acctattgcc
    17701 aagttaattg atagctattc taaattgcca ggtatcggta taaaaacggc tacccgttta
    17761 gctttttata ctattggcat ggaggatgat gtcgttaatg agtttgcaaa aaatttattg
    17821 gcagccaagc gagacctatc ttattgctcc atttgtggta atttgacaga tcaggacccc
    17881 tgtgccattt gccaggactc aacgcgagac cagtctacta ttttgattgt agaggatagt
    17941 cgagatgtta cagccttgga aaatatccaa gagtatcacg gtctctacca tgtattgcat
    18001 ggcttgattt cccctatgaa cgggattggg ccagacgata ttaacctgaa aactctgctg
    18061 acccgcttga tggaaaatga ggtgacagag gtgattgtgg cgactaatgc aacagcagat
    18121 ggagaggcta catccatgta tatctcacgt gtccttaaac ctgctggaat caaagtaact
    18181 agactagctc gtggcttagc ggtaggcagt gatattgaat atgcagatga agtgaccctg
    18241 ttgagggcta ttgaaaaccg cacagagcta tagcagttct gtagttagat acgttcctaa
    18301 ttttgagata ggatagctat gatttgttaa attatgctat actaagagta atagcgttga
    18361 tacaggaagg aaaatatatg tcaaaagaaa ccttgatttt actatatggt gggcgttctg
    18421 cagagcgtga ggtatctgtt ctgtctgccg aaagcgtcat gcgtgctatc aattatgata
    18481 aattttttgt caaaacctat ttcattagcc agaccgggga ctttattaag acgcaagagt
    18541 tttctcaaac accgtctgcc gatgaaaaac tcatgacaaa cgcgacgatt gttgaagagc
    18601 aaaaaatccg tccgagcgat atttatgaag aaaaggcggt tgttttccct gttcttcatg
    18661 gcccaatggg agaagacgga tctattcaag gcttcttgga agtgcttcgt atgccttatg
    18721 ttggcactaa tatcttgtct tcaagcgttg ctatggacaa aatcactacc aagcgcgtac
    18781 ttgaatcagc aggaatctcc caggtacctt atgtggcagt tatcgagggt gaaaatatcg
    18841 acgataagat tgcagagatt gaaggaaaat tgacttatcc ggtctttgta aaaccagcta
    18901 atatggggtc aagtgtcggt atctcaaaag ctgaggattt agctggcttg cgtaaggcac
    18961 ttgatctggc cttcaagtat gatagccgtg tcctcgttga gcagggtgtt aatgcgcgtg
    19021 agattgaggt cggtcttttg ggaaatgctg acgtgaaaac gacacttcct ggcgaagtag
    19081 tcaaagacgt tgctttttat gactacgatg ccaaatacat cgacaacaaa atcaccatgg
    19141 aaatcccagc taagattgat gagtctatca tggatatcat gcgtgataat gctgccaagg
    19201 ccttccgtgc tatcggtggt tgtggacttt ctcgctgtga tttcttcctg actgaagacg
    19261 gcgacatctt cctaaacgaa ctcaatacca tgccaggttt cacccaatgg tctatgtatc
    19321 cactcctttg ggataatatg ggcctagctt atccagactt gattgaagag cttgttcgtt
    19381 tggctaagga aatgtttgaa aaacgcgaaa gtcacctcat ttaattatta tcaagattgg
    19441 aatcattcca atcttttttc ttgcaaaggt ttgcaaaaag aaataaaatg gaacaagttc
    19501 tggaggtgtt tatgtatcaa acgacagtaa aaggggaagg tctgtttcag gctctttctc
    19561 aaggatatgg cgaatcggtt cgtacctttg gggtaacgga gaagggtgag actccggtta
    19621 gtctagttaa tattggctta gctgcctgta tcaccatgtg tgtgcagggc tactatgcca
    19681 gccaagaagg caataaaacc atgcctgttc aggtggagag tcgcttggac aatcagcgtt
    19741 ttgaggtgtt gattggaatt ggtgagtcgg tttcagcgca gaagcagaaa gagattcttg
    19801 cctatgtgga aaagaaatgt aaagtcaaag ctcttttgag ggaagacttg cagtttgaga
    19861 caagttttta tgtcttagaa agtgtggagt aagatgtttt tagcaattga agaaatgcga
    19921 caaggtttat gagatgaaag atggtgtcct cactcaagtt cgataaaaag tggtataata
    19981 gaaagagcga aagctctttt ttagtttatt ggagaaaaca atgaaattaa ccctacacga
    20041 agtcgctcag gtcttgggcg caaaaaatga tattagtctt tataccgata ctgcattcaa
    20101 caaggtcgag ttcgatagtc gactcgtcac aactggcgac ctctttgttc cccttaaagg
    20161 tgcgcgtgac ggtcatgact ttattcctgt ggcttttgaa aatggctgcg tagtaaccct
    20221 gtctgaagtt agccttgatg ttcctcacat tctagtagag gactgcttgg ctgcgcttca
    20281 acaattagcg gcttactacc tagagaaaac aggggtagaa gtcattgctg tgacaggatc
    20341 aaacggtaaa acgaccacca aggacatgat tcacgatgtt ctggcgacga cttacaagac
    20401 ttataagaca caaggcaact acaacaacga aatcggtctg ccatacaccg tcctccacat
    20461 gcctgatgat acagaaaaac tggtcttgga aatgggccaa gaccacttgg gagatattca
    20521 tcttctatcc gaaattgcca aaccaagtct atcagttatt accctttttg gtgaagcgca
    20581 tttagaattt ttcggctcac gagaagagat tgccaaagga aaattacaga ttgcagatgg
    20641 aatggagcca ggtagtaaac tcttgatccc agcagatcca attgcggata agctcttgcc
    20701 gagccatgta gacctcattc gcttcggtga gcaggctgat ttgcaggtga ccagtctggt
    20761 cgagtcaaaa gatagcctga ccttcaccgt caattttatg gacggcgaca ttttcctccc
    20821 agtaacgggt aagtacaatg ccaccaatgc catggtagca agctacgtag gtaagacctt
    20881 gggtgtgcct gatgaggcaa tcaagtcagc cctagccagt ctaaacttga cccgaaaccg
    20941 caccgagtgg aagaaggcag caaacggagc agatattctc agcgatgtct acaacgccaa
    21001 cccaacggcc atgcgattga ttttggaaac tttcactagc attcctgcaa acgaaggcgg
    21061 caagaaaatc gccgttttag cagatatgaa agaactgggg agccagtccg tcgatctcca
    21121 caatcagatg attttgagcc tgtcgcctga tgtgctagac accgtcattt tctacggtca
    21181 ggatattgaa ggtctggccc agttggctag tcagatgttc ccgattggaa aagtctattt
    21241 ctttaggaaa aatgcagagc aggatcaatt tgaagatctg gttaaacagg ttagggaaag
    21301 tctaggaaaa gaggaccaaa tcctctttaa aggctctaat tccatgaatc ttgggaaagt
    21361 agtggaagca atagaaaagt agagaggaga gacctctctt ttttagcaag tcttgtcaaa
    21421 acatcgaaaa gttgatatac taacttttga ggaaagagag gattttaata agatgagtga
    21481 tttttttagc aatcagattt ctgaagcacc gaacctgaac gtattggaac atctgtttct
    21541 catgattatt tggtttttca tgctccatct ttgttttcgt tgttatcaaa aaagatggtt
    21601 tcatattgtt ttttggtggc ttcaatttat acagattgtc tccctttata cttggtatat
    21661 cgtagctgat tctcctcttt cagagagtct tcctttttat cattgtcgct tggccatgct
    21721 ctttattctt tgggcgaagc ccggaccttt gaaacgttat tttgcctatc tcggtctttt
    21781 tggatcgctt gcggccttta ttcatccagt atttgaccca tttgcatttc cacatctgac
    21841 cttctttact tttgttattg gtcactacgc cttgacggtt aattgtatgt tgtacctgtt
    21901 atctgattta gaaggggaga tgttgaaggg aaaagaggta gtgaaatata cgcttattat
    21961 gaatatgctg attctaggag tagctctttt aactggtgga aattatggat ttttgagaca
    22021 ggcaccttta gtgaatacta ataatcttcc tttgaatttc ttcttggtaa cctgcctact
    22081 ctgtttctct attttgagta tacaagctat gctgattgcc tatttgaaaa aagaaagcaa
    22141 acaaatgaat tcgcatatat tgaaaaaata agacttgaaa ttagtttttc aagtcttatt
    22201 tttagttttt aaatgcgcct tgtttgtagc taatccagaa aaagacaggg ataaaaatga
    22261 gcattaatcc agaatagatt ggcaatgtgt gactgtttag ggggtggatt tcaatcagac
    22321 catgtaggaa atgggagctg atgaagaaac cgaaaacgga ataaataata agagccagtc
    22381 gagcttttgt cagtggcaaa caggcacgaa tgacagccag tagacctgtt gaaccaagaa
    22441 cataataaga aagggtttgc atgtcatgca agtttaagta tccaaatact tgcattaaat
    22501 ggaaaataag gacactgaga acaaccatga gagcatttgg tagggctaag agaagagatt
    22561 ttctgagaaa atgtttttct acagggcgga tatttcgttc aaaagttagg ataaaaggag
    22621 gaaaaccttc gacaaattga ccaatgaggg tcatttgtac ttgaataaat gggaaaacta
    22681 acaaatattc tgctttacct agggcaatac tagcgataca gataaggcca agtaagaaag
    22741 agtagattgt tttgataaga aagatgggag caatgtggga gatgttatta acaacgcgtc
    22801 gtccctcaaa gagaatctca ggaatatcgc gaaattcaga atctaggagg actagattag
    22861 cgatttgtct ggtagcggga tcgccttctg ccataacaat ggaacaatca gcttcgcgta
    22921 gtgcaagaat atcattgacc ccatcaccgg tcattgcagt agtatgtccc tgtgctttga
    22981 gggtttggat gagcaatttt ttctgatgtg gggatacgcg accgaaaatg gcggttgttt
    23041 cagctctggc aattagttct tcgtcgtcaa ctttggaaca atcgatatag ctatcgtagt
    23101 cagcaaatcc agcttccctg gcaatgtgtg agactgtcac aggattgtca ccagagatta
    23161 tttttagtgt cacttcttgc gagcgaagat aggccagtgt ttctgcggcg tcttctcgga
    23221 ttgggtcggc aatttctaat agagctagag gttcaatatt ctcaggtagc tgattttgag
    23281 aagaaagaag ggactgttgg ctaagcgcaa gaatcaggac acgggaacca cgagcctgtg
    23341 cctcagaaac agaaggagga ttttgtgtta gtaacatttc tggtgcccct agaaaaatgt
    23401 gaccaatgtt ttctattgtc attgcccccc attttctatc actagaaaat gggatgatgt
    23461 gactagcttt atagtggtgc tctaaatcac catattcttt tcgaatggcc tgagctgttg
    23521 aattagtatc ctcacttgtc tggatatagg tagcgagtat ctgttggata gtgtcaagtg
    23581 aataatggtt ggttaagggg agcaggtttt cgacggtcat tttcccctga gtaatcgttc
    23641 cggtcttatc caaacaaaga acatcaactc gggcaagtgt ttcgacggaa tacatttctt
    23701 gtacgaggac atttttcatt cccagtttga taacggcagt taagagagaa gtgatggtca
    23761 gcagagcaat tccctttggt aacataccta gtagggcagt agagctggta ataactgagt
    23821 cttttaaggg aagaattttg atgaaaaagg cttctagaaa aagagcaagt ccgaatggaa
    23881 tgataatttt tcctgtaaat ttagcaattt tatccatatt gtaaagaata cgagagacga
    23941 taggtttgtg agttttcgcc tcaagcatga gcttattggc atagttttct gcgccaacat
    24001 ggatgacttt tgcataaatc tgtccgctaa ctagatagct accagacaat aattcagccc
    24061 cagtattttt cacaatcaag tcgctttcac cggttaacat ggcctcgttt gtctcggcta
    24121 taccttctaa aacaatagca tcactaggaa cttgttcgcc agcagacagc aagagaacat
    24181 catctaagac aatatcttct ggtgcaatag atattgtctc gctatcgcga acaactcgga
    24241 taaaatcctt gttcatcagg ttgagtttgt caatcattcg tcgtgctcgc cattctgtca
    24301 gcattcctga aacagcgttg aggacaataa ctccgaagaa gaaaaggttg gaccatgcct
    24361 gaacagctag taaggctaag aaaatggcaa aatttagtgc gttaaaagat gtaaacacat
    24421 ttcgtctgaa gatttcccaa ttactggcac tggtctttgt cttaaaatga ttggtttgct
    24481 ggttttgaat acgttcttgt acttccttgg ttgataaacc ttttatttgt ttgttcatta
    24541 ttttatcttt ctttttctag tatatagaat acatctcata cttattgtaa catatttata
    24601 atacaatagt ataggtctgt agacctattc ttcaatagtt tgaaaaattc ccttatttcc
    24661 gatataataa gagagttgtc tagtaaagaa taaggatgaa tccaatgtaa atcgaatagg
    24721 ataagagctc agctctgcta tgaatcaaaa tacaaaaaat gaaaaggaaa cattatgtca
    24781 ctacaagaag aaatcaagaa acgccgcacc tttgcgatta tctctcaccc ggacgcgggt
    24841 aaaaccacca ttaccgagca gttgctctac tttgggggtg agattcgtga agcaggtacg
    24901 gtcaagggga aaaagactgg taactttgcc aaatctgact ggatggatat tgagaagcaa
    24961 cgtggtatct ctgttacctc atctgtcatg cagtttgact atgcaggcaa gcgggtcaat
    25021 atcctagata caccagggca cgaggacttc tcagaagaca cttatcggac cttgatggcg
    25081 gtggatgcgg ctgtcatggt ggtggactct gccaagggta tcgaggccca gaccaaaaag
    25141 ctctttgagg ttgttaagca ccgcaacatt cctgttttca cttttatcaa caagttggac
    25201 cgtgacggtc gtgagccact tgatttgttg caggagttgg aagaagtctt gggcattgcc
    25261 agctatccaa tgaactggcc gattggtatg gggaaatcct tcgagggact ctatgacctc
    25321 cataacaaac gtttagaact ctatcgaggt gatgagcgtt ttgcaagctt ggacgagggt
    25381 gacaagctct ttggttctaa ccccttttat gcacaagttc tggatgatat tgaacttctg
    25441 gcggaagctg ggaatgaatt ttcagaacag gcgattttgg acggcgattt gacacctgtt
    25501 ttcttcggct cagccctgac aaactttggt gtgcagacct tccttgacac cttcttggaa
    25561 tttgctccag agccacatgg tcacaagaca acgacagggg atgtcattga cccgctcaat
    25621 aaagattttt caggctttgt cttcaaaatc caagccaaca tggaccctcg tcaccgcgac
    25681 cgtatcgcct ttgtccgtgt ggtttcgggc gaatttgaac gcggtatggc ggttaacctg
    25741 cctcgtacag gtaagggagc caagttgtcc aacgtgacgc agttcatggc cgagtcccgt
    25801 gagaatgtgg aaaatgcagt agcgggtgac attatcgggg tttacgatac agggacttat
    25861 caggtaggag ataccttgac cgtaggcaag aacaagtttg aattcgagcc gctaccgacc
    25921 ttcacccctg aaattttcat gaaagtttct gccaaaaatg tcatgaaaca aaaatccttc
    25981 cacaagggaa ttgagcaact ggtgcaagaa ggagctatcc agctctacaa gaactaccag
    26041 acaggcgagt atatgctggg tgccgttggt cagctccagt ttgaagtttt caaacaccgc
    26101 atggaaggcg agtacaatgc cgaagtagtc atggctccaa tgggtaaaaa gacagtccgc
    26161 tggatcaagc cagaagacct ggatgaacgc atgtcatcaa gtcgtaacat tctagctaaa
    26221 gaccgctttg accaaccagt tttccttttt gaaaacgact tcgccctccg ctggttcgcg
    26281 gacaagtatc cggatgtgga gttggaagag aagatgtagc ggaaagacag aaatcagtaa
    26341 tcaacaaagt tgatttgatt tcgtcgtctt tccctcgcaa gggcggcgtc caaagaactc
    26401 gagcaatgcg aagagtgatt tgttgtgacg cctactgcgt cgaggttcag tgaacttttt
    26461 ctagtggtag atgagagctg atggtaatca gcttaccttg ataaagataa ctataaaagg
    26521 atatgataga atacatgaag ctgggcaaga catctatgat gtcttgccca gcttcatttt
    26581 taggctcttt gtcaactgta gtgggtagat gaaaagctaa cacctagaga ggacgaactt
    26641 cgttctctct ttctttatgt tcaaagcaat caaaatgcgt tttttaaagt tctcaaagtt
    26701 cctgaaacca aaggcatttc tcttaatgac tttgatgaga ttattagtag cttccagttt
    26761 ggcgttggaa taaggcaatt ctagggcatt caaaaccttg tctttatcct ttagaaatgt
    26821 cttaaatacc gtctggaaaa taggattaac agtggctatt tccagttcga cgatgtcaaa
    26881 gaaatggtct gagttcttct cttggaaatg gaataagagc aattgataga gttcatagtg
    26941 ctgtcgtagt tcctcggaga aagacaggag tttttccagt atttccttgt tagtcaaatg
    27001 cattcgaaac atagggggat aaaatcgttt atcgctgagt ttacgactat cctgttgaat
    27061 caatttccag tagcgtttca aggctcggta ttcctgcgag gttctgtcga attgattcat
    27121 aatttgaata cgaacacggt tcatagcacg gccaaggtgt tgcacaatat gaaagcggtc
    27181 gagtacgatt tttgcattcg gaaaaagctg tttagcaagt tgataatagg gactaaacat
    27241 atccatggta atcactttga cctgatttct aacctttcta ggatagcgta gaaagtggtt
    27301 tcggatggtt gcttgagttc ttccgtcgag aatggcgatg acgtttaggg agtcgaaatc
    27361 ttgagcgatg aagctcattt tccccttctt gaaggcatac tcgtcccaac tcatcacttc
    27421 aggtagggta ttccaatccg tttcaaactt gaactcattg agctttctca taactgatga
    27481 tgttgagata gatagcctgt gtgcaatatg tgtcattgct tgattttcga tgagtaattg
    27541 agcgatcttc tgactaacag cgacggagat ttgatggttt ttcttaacaa gaggagtttc
    27601 agcgcccgcc attttcccac attctttaca cttgaaacga cgctttttaa ggcggataag
    27661 gagtggataa ccagcagttt ctaggtaagg gatttttgat gctttctggt agtcgtactt
    27721 agccatttgt cctttgcatt ctggacattt aggagccatg taatccaagt aaccgtggag
    27781 ttctaagtga gttcccatat catattcatc agtgatagtg atatttttgt ctttaattct
    27841 gagaaaattt gtgataagat ttagttgttc catatgagtc tttctaatgt gagtgtggtt
    27901 gcttttcatt ataggtcata tgggactttt tttctatact caaaaaggct ccataatctc
    27961 cacggtggtt ttacccacta cagaaattat agaacccatt tttaaaaggt gtaatctttc
    28021 agaatttcaa tagactcaat ttttacatct gttttaggtt tatcgctatt gtctgtttcg
    28081 actgaagcga ttttatccac gatgtccatc ccttcaatga cttgaccaaa tacggtatgc
    28141 ttgccatcta agtttggatt gcctccgttt ttataagcgt caatgatttt accaggatag
    28201 ctagaactag agagttggct agacatgtct gttgtatttt gattgatgaa aaactgactt
    28261 ccatttgttc ccgcgccagc gtttgccata gaaagtgagc cacgaatgtt atagaggaaa
    28321 gctgaaatct cgtctttaaa accatttcca gcatcgatag tagtatcttt tccggcccag
    28381 atagactctc caccagtacc atttccaaga ggatcgccac cttgaatcat gaaatcctta
    28441 atgacacgat ggaagatcgt tccattatag tatccttcct tcgcatgagt cagaaagttt
    28501 tccacagtta gtggtgcttg ctcggggaag agttttatag tgatgtcgcc ttcggttgtt
    28561 tttattttaa tagcagcctc attttcacca atttcattgg aaagttgggg gaatgtagct
    28621 ttgggattgt taatggcgta tgccaaatct ttggcatatt ggctagaagc agttgtatca
    28681 gctgtcgtag tcgagcttgg actagaacta gatgctgtag aagatgagct attagctgtc
    28741 gagttgtttg tgcaggcagt tagcaagatg ctcgaagcta gagcaagaac tagtattttt
    28801 ttcattgaaa atcctttctt gtcttgttca aaattatgct cattctacca tgaaatatgg
    28861 attttttcaa tttttatcta gtataaaaag cgtatctaaa acaataatat gatatactat
    28921 atttaaagat gtaaaaggag aataatgatg tttgagaact tgtttgaccc agatggaagc
    28981 ctagtatggc atacggccct tttctacagt ttttccgcaa tcatattagc gacagtttgt
    29041 ttccatatca ttaaaaattt tatggaatgg caccacaaca atcgggcgcc caaagaatct
    29101 tgcaaggcta agcttgtctc taaacgaacc catgtttttg gtaacgaagt agcacgaacc
    29161 aattattatg taacgtttga atgggaggga aaacggcagg aatttcgcct tcgttcagat
    29221 gaatatgccc ttttagcaga gagagatgta ggcaccctgc attttcaggg gactcgtttc
    29281 ctaggttttg aacggctcta agagtcgttt ttctttggag aatatcccta tctagtgtat
    29341 aatggtttga acacatgttc gtacaacgca aaagaggtat ttaagatgat tcaatcaatc
    29401 ggacaagtta tgttatatgt gaatgatatt gaggcttcag ctcaattttg gaaagagaaa
    29461 atgggatttg aacgtgtaga aaaacaagtg caaggccccc aaacttctta cattattgca
    29521 cctaaatcag atagtgaggt acaatttgta cttcatgata aggcggaggt tgctgagatg
    29581 gagccagaat taaacttagg tacaccatca atcttaatga catcagtaga tgtagccaaa
    29641 acttacgaag aacttgttga acgtggtgtc acaacgaatc cagtcatgga ccttggtttc
    29701 atgaaggtaa ttagctttgc agacaatgat ggaaattatt acgcaattcg tgaggtaaag
    29761 taaatgtcac tccagaatcg tgttgaagaa atgtataaag accacgaggt caaaccctat
    29821 atttcccccg agcgtgactt ggcagcctgg ctgttggagg ccaagcccgt tcccaaacgc
    29881 aatatggttc gtctggaaga aggtattttg ccaggagata ttattttgct atggcggatt
    29941 agcctgggtt cttttgaatc gacgacgccc tactccaagt actttgagta catgtatggt
    30001 atcaatggtc ctgctcacat ggagcagttg atcgcagacg gttatgccta tgtggaatcg
    30061 gcctttgatt ccctagacca catcacttct actgccaaga aaaatatcct caaagcagag
    30121 ggtgtgacag gcctatccaa gatgaaggcg gcagacctcg acactgccct caaggacaac
    30181 ttgacggaag aaaagttagc tccatacttt accgtccgag gttatgccct gacggaaaaa
    30241 ggcagagctg cactcgataa tcacccagaa gtgcttgcaa aacacccaat gaagaagatg
    30301 tacaaataaa atagaaaaga tttttaaacg gcactcaaaa gttagaatca ttctagcttt
    30361 ttgggtgttt ttatttgcta acaagtcaat ttttcttgac agaaaacgct atcaatgata
    30421 ttctagtgta aattattgaa acgtttcaaa agaaaggggt aaaccatgga agaacaaaaa
    30481 tcaattacta tgaaagatgt agctcgagtt gcaggggtca gtgttgggac agtttcaaga
    30541 gttatcaaca atgagccagg tattaaggaa agtacgcttg aaaaagtcaa tgctgccatt
    30601 aaggaattga attacattcc agatgtttat gctcgtggca tgaagaagaa caaaaccgaa
    30661 actatcgcct tgattattcc gacagtttgg catccttttt ttggagaatt tgcctatcat
    30721 gttgaagtgg aactgagtaa gaaaaattac aagttgctcc tttgcaatat ttctggtcca
    30781 aaaagggagt tggattatct gactatgctg caacaaaata aggtggacgg cattattgct
    30841 atcacctaca gtccaatcga ggattactta tcttctaaca ttccattcgt cagtatcgac
    30901 cgcacctatg aaaataaggc tatcccttgt gtcagttcgg acaaccgagc tggtgcggaa
    30961 ctggcagcga ataccttgat agcaaaagga ggtcgccatt ttgcctttat cggtgggcac
    31021 aataaaacaa tcaatgaaac caagaagcgt agattgtatt ttgaaaagag gattttagag
    31081 gcaggttttc cttgtcatgt cttggacttg gaagagccat atgatgactt tgtcggtcaa
    31141 gtcgaagagt ttctgattaa caatccacag gttgatgcta ttttcaccat caatgatttt
    31201 acggccctag acacacttgc tgttttggaa aaactgagac gacgggttcc agaagatgtg
    31261 caggtgattg gctatgatgg tattcagttg gcaagtgaaa aatctttagc cctttcgacc
    31321 attcgtcaac ctttggagtc tatggcccaa gaagccgttg cctgtctaat tgatattatt
    31381 gagaaaagag agcgccccct acaagtcact ctaccgattt cctatcttga aggaaaaact
    31441 acaaaaaatt tttaaaaaag cagttgacag aaaacggtta caattgtaaa ataaaaccat
    31501 caataaacag ttggttttat tttcacaaga aaaatgaaac gtttcaaaaa ggagttctta
    31561 tgaaaacatc aaaactgcaa caagctagtc tattcgatag aatcaagcaa cagaaactct
    31621 tgttactgat gttactacca ggcttggtct tgactttcat cttccgttac attcccatgt
    31681 acggagtgct gattgccttt aaagactata atcctttaaa aggggtgctt ggtagtgagt
    31741 ggattgggtt tgaagagttt accaagtttc tctcgtctcc aaatttcggc accttacttg
    31801 ccaacacctt gaaattgagt gtctacggtc tgctcttagg atttcttcta ccaattattt
    31861 tggccatcat gctcaatcaa ctattgagcg ataaggctaa aaaacggatt cagttggtgc
    31921 tctacgctcc aaactttatc tcagtcgttg tcatcgtcgg tatgattttc ctcttcttct
    31981 cagtaggagg accggttaat tccatcctag gtatgtttgg cattgaagcc aacttcctga
    32041 cagacccaga cttcttcaga cccctctaca tcctcagtgg tatttggcag ggaatgggct
    32101 gggcatcgac tctttacacg gctaccttga tcaatgttga tccagccttg attgaagcgg
    32161 ctaagctaga cggtgcaaat attttccaac gaatctggca tattgactta ccagcactaa
    32221 aaccagttat ggtcattcag tttatcttag cagctggggg catcatgaac gttggttacg
    32281 aaaaagcctt tctgatgcag acttccctca acctgaccag ttctgaaatc atttcaacct
    32341 atgtctataa aatcggtttg gtgtcagggg actactctta ttcaacagcg gttggcttat
    32401 ttaacgcact tatcaatatt attctgctga ttgcagtcaa taagattgtc aaacgcatca
    32461 acgacggaca aggcttatag gaggttcgta tgaatacaca aatgtacaca aaatttgaca
    32521 agcgaatgct ggttgtcaat aaaatcttgc tggcatttct tgttctcata acagttgtgc
    32581 ctatggtcta tatcttagta gcgtccttca tggatccaca ggccttactt agcaagggaa
    32641 ttagctttga tccaaaggac tggacagtag aaggttatca acgggtattt tcagacaagt
    32701 ctatcctacg cggatttttc aactccctct tttattcctt ctcctttgcc ttcgtgaccg
    32761 tgtctatttc agtcatgact gcctatccac tctctaaaaa agatttggtc gggaaaaaat
    32821 ggatcaatgc cttccttgtc ttcactatgt tcttcggtgg tggacttgtt ccgacctatc
    32881 tcttggttaa agatttggga atgttgaata ctgtctgggc cattattatt cctggtgcag
    32941 tcaatgtgtg gaatatcatc ttggcacgga cctatttcca aggcttgcca gatgagttgg
    33001 tagaagcggc cgtaatggac ggtgctaatg aatttcagat tttctggaaa atcatgattc
    33061 cactagctaa gccaattatg tttgtgctct tcctctatgc ctttgtcggt caatggaatt
    33121 cttactttga tgccatgatt tacatcaagg acccagactt ggagccactc caactagtac
    33181 ttcgtaaaat cctcattcaa agcgagcctg ctaaggacat gattggtgcc caggctgcca
    33241 tgaatgaaat gaaacgaatc gcagaaatga ttaagtatgc gaccattgtc atctctagct
    33301 tgccactcat tgtcatgtat ccattcttcc agaaatactt tgacaagggg attatggctg
    33361 gttcactaaa aggttaaaat tgttcaaaat ttttatagaa aacaaaacag gaggttgttt
    33421 ctgatgaaac acacatttgg aaaaacagtt gttacacttc ttgcaagtac cgttttattg
    33481 gctgcttgtg gctcaaaaaa tactgcttca agccctgatt atgaattgaa agatgttcaa
    33541 ttccctttgg aaaaatccgt tacacttaag tttatgacag ctagttcacc tctagctcca
    33601 gccgattcaa atgaaaaatt aattttcaag cgtttagagg aagaaactgg cgttcatatt
    33661 gattggacaa actaccagtc tgattttggt gaaaagcgga acttggacat cgcttcaggt
    33721 gatttgccag acgccatcca taatgacggg gcttctgatg tggaattgat gaactgggct
    33781 aaacaaggtg ttattgtacc agttgaagac ttgattgata agcatatgcc aaacctcaag
    33841 aaaattcttg atgaaaatcc agagtaccgt tccatgatta cagcaccaga cggtcatatc
    33901 tactcattcc catggattga agaattagga gagggcaagg agtctatcca taccgttaat
    33961 gacattgctt ggattaacaa ggaatggttg gacaaacttg gacttgatat gccaaaaaca
    34021 acagatgact tgattaaggt tctcgaagcc tttaaaacac aggatccaaa tggaaacggt
    34081 aaggctgatg aaattccgat gggcttcatt aatggtggag gtaacgagga ctttaaaatt
    34141 ctatttggtg cctttggtgt aggcgataac gatgaccact tagttgtcaa caatgacggt
    34201 accgttgact ttacagcaga caacgaagac tacaaagaag gtgttgagtt catgcgtacc
    34261 cttcaagaaa aaggtcttct agattcggaa gcgtttgaac aagattggaa tacttacatt
    34321 gccaaaggta gtgaaaatct atgcggtgtt tacttcactt gggataaagc taacattaca
    34381 ggtatgaacg atacttatga catcttgcca gtcttggcag gtcctgatgg aaccaagcac
    34441 atcacacgta caaacggtat gggcttccaa cgcgaccgca tggttatcac ctcagctaac
    34501 aaaaacttgg aattgactgc taaatggatt gatgcccaat acaaaccaat ccagtctgtt
    34561 caaaacaact ggggtaccta tggtgatgaa acccaacaaa atatttttga actcgacaca
    34621 gcaaccaata gtttgaaaca cctaccattg gagggtaccg caccgggtga acttcgtcag
    34681 aagacagaag ttggtggacc gttggctatt cttgatgaat actacggaac cgtaacaacc
    34741 atgccagacg atgctaaatg gcgtttggac ttgatgcacg caacctatct tgactatgta
    34801 acaaacgatg atatttaccc tcgcgtcttc atggaacaag aagatttgga taagattgcc
    34861 caagttgaag cagatatgaa cgacttcatc taccgtaaac gtgcagaatg gattgtaaac
    34921 ggcggtatcg aagaagaatg ggatagctat ttgaaagaat tggaaagcta tggtctttct
    34981 gactggttag ctatcaagca aaaatactat gatcagtata aagaaaatca gtaatcaaaa
    35041 ggaggctgcc tgtgaaaaca gtagtagaag ccaatcaatt tattcagaaa gaaaaaggaa
    35101 acgttaatcc gattttcaaa ccacaagccc atttaacacc ggaaacaggc tggatgaacg
    35161 accccaatgg atttatctac ttccgtggag aataccattt gttctaccaa ttcaaccctt
    35221 acgagagtgt ttggggaccg atgcactggg ggcatgcgaa aagtaaggac ttggtcaact
    35281 gggaacaact tccagttgac ctagctcctg ataaagctta cgataaagac ggctgtttct
    35341 cgggctctgc cattgtcaaa gatgatgtcc tctggctcat gtacacaggt cacatcgtca
    35401 atgaagacgg gacagttagt caagttcaga acatggcctt ctcgactgac ggtattcact
    35461 ttgaaaaaat cgagcagaat ccagtcgcaa cagcagatgg actgccagaa gaagtgattg
    35521 ccaatgactt ccgcgatccg aagatttttg agaaagatgg tcactactac tctgttgtcg
    35581 caaccaagca caaggacaat gtcggctgta tcgtcttact cagctctccc aacctgacgg
    35641 attggaaatt tgagtctatc ttcttgaaag gtgaggccaa ccaaggcttt gtctgggaat
    35701 gtcctgacta ctttgaagtg gacggtcaag agtacctgat tatctctcca atgcgttacc
    35761 aaaaagacgg gaatgacttt atcaatatca actccaatat ctttgtgacg ggtcatgtgg
    35821 actgggacaa gaaagtcttt gtggcagaat ccttcaagga aatcgaccat gggcatgatt
    35881 tctatgcagc tcaaacgact gaaggtccag aaggggaacg tgtcatgatt gcctggatgc
    35941 atacatgggg acgtccgctt gtaaccaatg acctaggcca taagtggtat ggtcaaatga
    36001 ccctgcctcg tctacttaag caaggtgaga atggactcag gcaggtcttg ccagcaggta
    36061 tcttgaacag ctttgacgac attgaaatcg gtcaagttat tcaaggacca agtaagctct
    36121 ccctcaaact ggacgacagt ctagacttga aactgggtac tgaccgagac tatcttcaat
    36181 ttggctatga taaagccaaa caagaagtct atattgatcg tagtcacctc aaaatccagc
    36241 aagttggtga ggaggaatgg tcaactgttc gtcgagcggt cacggttcaa gcgacagagc
    36301 tagaggtctt ggttgacacc aactgtttgg aaatctttat taacgatggt caagaaacct
    36361 tgacatcaac cttctacgta gaaggtcaga ttattctaaa cgctctataa tattatttgc
    36421 cctcttaaat tattctttca ctccaagaga aaccctgtat ttgcagggtt ttttctatca
    36481 tgaaaattct tcccgattat gataaaataa agagattgag aaagttgagg tatctatgag
    36541 aaagacaagt aaaaaaggaa aggctacgag gcgaccaacc aaggcagaat tagcacagca
    36601 agaacgtgtt aaaaatatca cccttcgagt attggggctt ttattcattg cctttgcagc
    36661 cagtcgccta ggtgtgtttg gagtgaccag ctacaatatt ttccggctat tatttggtag
    36721 tctggcctat ctattattgg tgggtgcatt tatctacctt cttattccca aagtcttacg
    36781 cgaaagagaa gggaccatat cgggcttctg gctgattgtt atcgggttat tgattgaatt
    36841 tcaggcttac ttagactgga cctatcaagg gagtgactta ttcggtcata ctctaaaatt
    36901 ggccttgtca gacctagcta agtttcaggt aacagcattt ctaggcggag ggatgattgg
    36961 aagtatcttc tatctgccag tctccttcct ctttgcaaat gtcggttcct tcttcatcgg
    37021 tcttctagtg atagcatttg gtatcttttt tgtaagccca tggtctgttt atgatgttgc
    37081 cgatggcttg gcggttgcca aagataagtt ggtggagacg caggtaaaaa gagcagagct
    37141 tcgaacacag aaaaaagcag aacgagaaga aaaacgtcag caagaattag ctcgtctaga
    37201 agaggaacgc cttcgtctag aggaagagga agagtcagct cgggctttgg cactggtaga
    37261 tagacatgtc aatttagaaa cgggtgaaat cctcgaagaa gagcctgttc aagtaccgat
    37321 tatttcagaa tatgaccact tagacataga agatgaattt cctattatgt tggcagaaga
    37381 tgaccaacca gcacaatcaa actcggcaag ccaggattct gaaacaaatg agtttgagaa
    37441 ggacgagaca gatgtgcaga ttgatttcaa gcctaagcag agactagcat ataaacttcc
    37501 gtccatagac ttatttgctc ctataaaagc taagagtcag tccaatgaaa aacgaattgt
    37561 tcgtcagaat attaaagttt tagaagacac ctttgccagt tttggaatca aggtagtagt
    37621 tgagcgagct gagattggac catcggtaac caagtatgaa gtcaaaccag cagtcggtgt
    37681 tcgtgtcaat cggatttcta acctagctga tgatttggct ctagcccttg cggctaaaga
    37741 tgtccgtatt gaagctccta tcccaggaaa atcactggtc ggtattgaag ttccaaactc
    37801 cgaagtggct acagtacctt tccgtgagct ctgggaacaa tctaaaacag acccagacaa
    37861 acttctggaa attcctctcg gtaaggctgt caatggttcc gtccgttcct ttaacctagc
    37921 acgtatgccc catctattgg tggctggttc aactggttca gggaagtctg ttgctgtcaa
    37981 cggtatcatc tcttcaattc tcatgaaagc tggtccagat caagttaagt tcatgatgat
    38041 tgaccccaaa atggtcgaat tatcggtcta taatgatatt ccccacctat tgattcccgt
    38101 tgtgaccaac ccacgcaagg ctgctcgagc tcttcaaaaa gtagtggatg aaatggagaa
    38161 acgctatgag ttgtttagcc aaattggtgt ccgaaactta gaaggttata atgcgaaggt
    38221 cgaagaattt aatagccgtt cagaagaaaa acagattcca cttcctctaa ttgtggtaat
    38281 cgtagatgag ttggcagact tgatgatggt agccagcaag gaagtggaag atgccattat
    38341 tcgcttggga cagaaggctc gtgcagcagg tatccacatg attcttgcta cccagcgacc
    38401 atctgttgat gttatttcag gtttgattaa agccaatgta ccatctcgta tcgcctttgc
    38461 cgtatcaagc ggtacagaca gtcggacgat tctagatgaa aatggtgctg aaaaactctt
    38521 gggccgcggt gacatgctct ttaaaccgat tgatgaaaac catccagtcc gcttgcaagg
    38581 ttcctttata tccgatgatg atgtagaagc aatagttggc tttatcaagg atcaggcaga
    38641 tgcagattat gatgaatcct ttgatccagg tgaagtggca gaaggtgatg gcgatgcagg
    38701 ttttggtgat gctggaggag atccactttt caacgaagca cgtgccttgg tagttgagac
    38761 acaaaaagcc agcgcctcta tgattcaacg acgcttgtct gttggtttta acagggcaac
    38821 acgcctcatg gaagagctag aagcagcggg tgtcattggt ccagctgaag gaacaaaacc
    38881 tagaaaggta ttggaaacac aataatgaaa tttgatgcag ttcatcatat tgcaattatc
    38941 ggtagtgact atggcaaaac aagagaattt tatgttgaga aactaggctt tgaacaggtg
    39001 gatgaacata tccgaccaga aaaaaatgat attctcttca atgtcaaaaa aggcaatctg
    39061 atcttggaaa ttttcatcaa accagatgcg ccaatgcgtc cggccatgcc caatcctgaa
    39121 catacaggcc tacgccatct agccttccag gttgcagatg tggaagcttg tctggaagag
    39181 tttgaccgtt tggacatccg acatgaagtc ctgcgaacag atgattttga tggtaaaaaa
    39241 atggccttct tctttgatcc agatggcctc cctctagaaa ttcatgaata agtccatctt
    39301 ttcatgccca gagaggccta tcaatatgac aactaattaa tactcttaga aaatcaaaat
    39361 catacgctgt tgacttgatt tgatgaaggt cagttctatc tatagtcatt tgaattaact
    39421 ttgatacatc gtcactttcg gcttgccgta ctctgcagaa gtgacttgct ttgaaagtta
    39481 tatctccaac ctagcacagc cactaggctg tgctagcaac ctgcacctca gttccttgtc
    39541 tgaaagctaa ttcattcgac tatacatcta cgtcgccttg tctgatttag tataaaaaga
    39601 atccccactg cgcctgcaat ggggatttat tatgccatct atgaaaggat ggatgatttt
    39661 aggattttaa agtgaagacc gcaataacca aagctagata catcaaaaaa gtcaagataa
    39721 aactagctcg ccagaaaacc ttgaagaaac gtcgatataa aaaattcttt ttctttaaaa
    39781 ggaagaaacc gcaaagacca atcgctagta gtgagagggc taggacaagc tgaggcagta
    39841 gactgttata gtaggccttg tccgaaatca gataaaattc aattgcatag agaggaaagg
    39901 caatgtctgc aaagttccat cctcggtttt gcaacctaaa aaacttgaca gcaattatcg
    39961 aaatggccaa ggttagaaag atgaatagaa aggctactat ttttaaaaat ataatcgatt
    40021 caaacataca ttcattctat aaaaaatgtg aaaaaaagta aacctaaagc ttgcatttct
    40081 ttgaaattcg tgtataatga aaaggtatgt gtaaaacaca tatttgtggg aggtaaaaat
    40141 ctttaattac cgccaaaacc acaataggag gattttatat catggctaaa aaagtcgaaa
    40201 aactcgtaaa acttcaaatt cctgcaggta aagctactcc agctccacca gtcggaccag
    40261 cacttggtca agcaggtatc aacatcatgg gattcacaaa agagtttaac gctcgtacag
    40321 ctgaccaagc tggtatgatc atcccagtag ttatctctgt gtatgaagat aaatcattca
    40381 ctttcatcac taaaacacca ccagctgctg ttcttttgaa aaaagctgca ggtgttgaaa
    40441 aaggttcagg tacaccaaac aaaactaaag ttgcaacagt tactcgtgca caagtacaag
    40501 aaattgctga aactaaaatg cctgacttga acgctgcatc tcttgaagct gcaatgcgta
    40561 tgatcgaagg tactgctcgt tctatgggat tcactgttac tgactaagta gcacccaaga
    40621 ttatctgatt acaaggagac atataacatg gctaaaaaaa gtaaaaactt gcgtgctgct
    40681 cttgaaaaaa tcgacagcac aaaactttac agcgtagaag aagctgttgc tcttgcaaaa
    40741 gaaactaact tcgctaaatt tgatgcgtca gttgaagttg cttacaactt gaacatcgac
    40801 gtacgtaaag cagaccaaca aatccgtggt gcaatggtat tgccaaacgg tactggtaaa
    40861 acttcacgcg ttcttgtttt cgcacgtggt gctaaagcag aagaagcaaa agctgctggt
    40921 gcagactttg ttggtgaaga tgacctcgtt gctaaaatca acggtggttg gttggacttc
    40981 gacgttgtta tcgcaactcc agatatgatg gctgttgttg gacgtcttgg tcgtgtactt
    41041 ggtccacgta acttgatgcc aaaccctaaa actggtacag taacaatgga tgttgctaaa
    41101 gcagttgaag agtctaaagg tggtaaaatc acttaccgtg ctgacaaagc aggtatcgta
    41161 caagctctta tcggtaaagt atcatttgac gctgacaaac tcgttgaaaa cttcaaagct
    41221 ttccacgatg taatggctaa agctaaacca gctacagcta aaggtactta catgacttca
    41281 gtatctatta caacaacaca aggtgttggt atcaaagttg atcctaactc actttaatca
    41341 atagaaagat tgtcttaggg caatcttttt ttcttgagat tttcttgaca agcacttgat
    41401 ttcgatttat actatattca atttacataa aaggagttat ccgatgaaag tagcagagaa
    41461 agaagagctt tataaatacc tttctgcagc ctacaacctt ccgcaggaag cattttcaga
    41521 agccctgcgt gaaaaaatat tggaggtggc aggtcagctg gacaaggagg aaaatctcta
    41581 tatactggca ggacacttaa gtcgctttat caatgcagag ttaacagctc tgacttgccg
    41641 agcgcctaag gaattggtgc aactagccca ttaccttcaa gaggttcaaa accattatcg
    41701 ctatgctagt ctttttccag gaaaggtaaa ataggagaaa acatgacaga atatacaaaa
    41761 ccactcgttt ggaagtggga agatgaaaat gacaaccgat ctggcaaccg tccaacagca
    41821 ggcagtcgct ttgagcaaga cctaccaagg ggagagaagt ctttccaagt ctattcatta
    41881 ggaacgccga atggcattaa ggttgctatt atgttggagg agttgaaaga gttaggtatt
    41941 tcggaagctg attatgacct atttctcatc aatatcggtc aaggagacca atttggctcc
    42001 gattttgttg ccatcaaccc caactccaaa ataccagcta tggtagatta ttccgagcaa
    42061 gaaccgattt cggtctttga atcagccaat attctcctct acttggcaga aaagtttgag
    42121 gccttcctgc caaaagcttg ggcagagcgg acagaggttc ttaattggct cttctggcaa
    42181 actggcgccg ctccatttgt tggtggagga tttggacatt tcttccatta cgctccgaca
    42241 gcgcaagaat atccgattaa tcgctataca atggaaacta agcgtcagct agatctcttg
    42301 gatcagctat tggcgacaag agaatatata gctggaaata cctataccat cgcagatatt
    42361 gctatttggt cttggtatgg tcgcttggtg caaggagaac tatatccagg ttcggcagaa
    42421 tttttagatg ttgattctta caagcatcta aagacctggg tagataaaat agctcagctc
    42481 ccagctgtac aacgagggtt gacagtgaaa tatcattcaa ttgataatta attgacttgc
    42541 ccaccttatg ggtgggtttt tcttttactt tggtatgata aaagtttata atgaaagagt
    42601 tagactttgt gaaaatcca
//
LOCUS       DBNFCO010000007        39838 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.007, whole genome shotgun sequence.
ACCESSION   DBNFCO010000007 DBNFCO010000000
VERSION     DBNFCO010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 39838)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39838)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39838
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.007"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            7..807
                     /locus_tag="AC1PIV_000328"
     CDS             7..807
                     /locus_tag="AC1PIV_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HIP6611382.1"
                     /translation="MKKILALAATVLAGLTLAACSSTSSQSALDKIKEKGTLVVATSP
                     DYAPFEFQALVDGKNEVVGADIMLAQKIADELGVKLEVSAMSFDNVLSSVQNGKADIA
                     IAGLSYSEERAKVFDFSESYYQISDVLLIKKDSANSLTSIDAMSGKTLAVQKGSTQES
                     YAQENISQANLISLTLMGEAVNELKSGKVDAILMDSPVAAGYVSQNSDLAVASVEFPT
                     IDENSKVIALPKGSTELKTAIDKVIAEVKASGEFDTFLEKAATYTSVE"
     gene            complement(935..2773)
                     /gene="glgB"
                     /locus_tag="AC1PIV_000329"
     CDS             complement(935..2773)
                     /gene="glgB"
                     /locus_tag="AC1PIV_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009909892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003844 - 1,4-alpha-glucan branching
                     enzyme activity [Evidence IEA];
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_function: GO:0043169 - cation binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HIP6611383.1"
                     /translation="MTEFTDLDLYYMNTGEHTTLYEKMGAHIIKERNKIIGTQFRVYA
                     PNAREVFLVGNFNEWQRSHSMEREIDGVFQLYVDGLKSLEDYKYLIITHDGREIYKAD
                     PYAFFSQVRPDTASTTYNSRYKFKDDIWMYNRVNYDFKEQPVSIYEVHLGSWKQKFAN
                     KNEGGAPVEAFNSYKEITPLLIEHIKENNYTHIELLPITEHPLDASWGYQVTGYYSPT
                     SRYGKPDELKYLVDQCHQAGIGVILDWVPLHFCKDAHGLYQFDGSWLYEYSYEQDREN
                     HQWGTANFDLGKGLTRSFLLSNLKYWLEYFHFDGIRVDALSYLLYWRGETDEDKINHA
                     AIDFIKRVNAMVHTDYKGVLMIAEDSSSFPKVTHPLEDGGIGFDMKWDLGWMNDTLKF
                     VERPAIYRKYHSNEITFGMYYNQNEQFLLPLSHDEVVHGKHSIIEKMNGDYEDKFHLA
                     RVYYSFYFAHPGKKLLFMGNEWGHIREWHEYTEMDWGLLQFPIHHSFYQMMKTLSTFY
                     KEHDAFWKYDYQAYEKGFNWVKIDEEASLYAFSRTSDVQEILTIHNFNDQELFDVHLD
                     LPADSEYKLVFSSNAIPMDTFSLYPDENGARITVPRLTSFYLERVK"
     gene            complement(2846..4291)
                     /gene="glgA"
                     /locus_tag="AC1PIV_000330"
     CDS             complement(2846..4291)
                     /gene="glgA"
                     /locus_tag="AC1PIV_000330"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004373 - alpha-1,4-glucan
                     glucosyltransferase (UDP-glucose donor) activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HIP6611384.1"
                     /translation="MTKKSVLFVASEGLPFIKTGGLADVIGSLPKELVKQGLDVRVVL
                     PLYKKIAVNNHSDFDYVSSFDVRAGDIQSMANVYSQVVDGVTFYFIEHRDFFERDELY
                     GYDDDAMRFGYFQHATCRLLEALHFFPDVMHTHDWHTAALPFLCRTFYSYREEFRNIK
                     HVFTIHNLAFQGIFHKQALWSALGMDYSYYLDGIARFHDECISFMKLGILYADKVTTV
                     SETYAREILTEEFGENMQHVLELRKYDLVGIVNGIDYDSWDSQTDQYLVRNYSLETIE
                     SKKANKLALQSQFALPQDENVLLIGIVSRLTWQKGFYLLTEVLGHLLQAHVQFVILGN
                     GEEDIENAFNHFKHAYPDKFAFYRGYNEPLAHQIYAASDLFLMPSMFEPCGISQLISM
                     HYGTLPLVRETGGLVDTVAPYNMSTKEGTGFSFGGRDAYNMRQVYDLALQTYYDRPDD
                     WYAMVEQAMKRDFSWTASAEKYIWLYREISG"
     gene            complement(4300..5415)
                     /gene="glgD"
                     /locus_tag="AC1PIV_000331"
                     /pseudo
     CDS             complement(4300..5415)
                     /gene="glgD"
                     /locus_tag="AC1PIV_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922501.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
     gene            complement(5428..6555)
                     /locus_tag="AC1PIV_000332"
     CDS             complement(5428..6555)
                     /locus_tag="AC1PIV_000332"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HIP6611385.1"
                     /translation="MAQNKMLAMILAGGRGTRLEGLTKKVAKPAVAFGGKYRIIDFPL
                     SNCANSGIDIVGVLTQYEPVLLNSYVAQSQRWGLDVQGSGVFVLPPSEKIEGFGLYKG
                     TADAITQNIDFIDLHDPEHVLILSGDHIYKMNYDKLLDTHIQKKADATIAVIEVPIKE
                     ASRFGIMNTDEDYRIEEFEEKPENPKSNLASMGIYIFTWKTLKKYLQEDDKLDTSSHD
                     FGHDIIPKYLEDGRTLIAHPFRGYWKDVGTVNSLWESNMDLIDHAGDLDLSDRSWRIY
                     SEDKGSPAQVIGATATVKSAYIDKGAIIDGTVEHSVISTDVQVNQNAVVKNSVILPGA
                     IIGEGVELDYVIVAENIKIADGVKLTGDIDHILLIDKNVTK"
     gene            complement(6719..7630)
                     /locus_tag="AC1PIV_000333"
     CDS             complement(6719..7630)
                     /locus_tag="AC1PIV_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HIP6611386.1"
                     /translation="MRIQQLYYIIKIAETGSMNEAAKQLFITQPSLSNAVRDLEKEMK
                     IKIFFRNSKGITLTKDGMEFLSYARQIVEQTELLEDRYKNPNAKRQLFSVSSQHYAFV
                     VNAFVSLLKETEMEDYELFLRETRTWEIIDDVKNFRSEIGVLFLNHFNRDVLLKLLDD
                     NRLSYTTLFTAKPHVFVSKTNPLAQRKSITLDDLVDFPYLSYEQGIHNSFYFAEEILA
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLEFDDEIELVYI
                     QHEKALLSDMGEKFINYLLEEVKFDQK"
     gene            7844..8617
                     /locus_tag="AC1PIV_000334"
     CDS             7844..8617
                     /locus_tag="AC1PIV_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HIP6611387.1"
                     /translation="MILKEQMLLVDQVQLAPRIFAMTLQGDMVQDMKMGQFIHIRVPD
                     DSMLLRRPISISEIDRNKSQCRIIYRVEGQGTEVFSKMTVGQYLDVMGPLGKEFEVDF
                     LKEGDRILIIGGGIGVPPLVEVAKQAAFRGVNVTSVIGFATKEAVILEEELASYGMVY
                     VTTDDGSYGRKGNVATVVEELTNEFAAIYSCGAPAMMNYVDQRFQEHPHAYISLEARM
                     ACGMGACYACVVKPKEGQEHENKRVCKEGPVFATGSLIL"
     gene            8627..9568
                     /locus_tag="AC1PIV_000335"
     CDS             8627..9568
                     /locus_tag="AC1PIV_000335"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HIP6611388.1"
                     /translation="MTKRLAISLPGLDLKNPIIPASGCFGFGQEYADYYDLNQLGSIM
                     IKATTRHPRYGNATPRVAETPAGMLNAIGLQNPGVEAVLSEKLPWLEQHFPDLPIIAN
                     VAGFSNEEYAYVSGKISKAPNVKAIELNISCPNVDHGNNGLLIGQVPELAYQAVKAAV
                     EASSVPVYVKLTPSVADITLLAKAAEAAGATGLTMINTLVGMRFNLKTRQPILANGTG
                     GMSGPAVFPVALKLIRQVAQMTDLPIIGMGGVDTADKAIEMMVAGASAIGVGTANFTD
                     PFACPKIIQDLPKRMEVYGIDSLEGLRREIRYSLGKR"
     gene            9733..10428
                     /gene="pyrF"
                     /locus_tag="AC1PIV_000336"
     CDS             9733..10428
                     /gene="pyrF"
                     /locus_tag="AC1PIV_000336"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HIP6611389.1"
                     /translation="MKETRPIIALDFAGKEEVQSFLEQFPPDEKLYVKVGMELYYAEG
                     PGIINYLKDCGHSIFLDLKLHDIPNTVESAMKVLAKLGVDMTNVHAAGGVEMMRAARR
                     GLGKDAVLIAVTQLTSTSEEQMRTDQNIQTSLQEAVVHYAQRAQEAGLDGVVCSAHEV
                     ALIKDATSSDFVCLTPGIRPTGGEVGDQKRVMTPADAARIGSDYIVVGRPITKSEHPY
                     QTYLSIKEEWNRG"
     gene            10421..10747
                     /locus_tag="AC1PIV_000337"
     CDS             10421..10747
                     /locus_tag="AC1PIV_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004427 - inorganic diphosphate
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0006796 - phosphate-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic diphosphatase"
                     /protein_id="HIP6611390.1"
                     /translation="MDKIYQVIIDRPLGYIDKFGNQYPINYGYVPNLLAGDGEEQDVY
                     IISKAVRQPLTAFEGKLVAIIHRRDDIEDKWVLTGLDEKLTVTEIKEKTNFIDQYFDS
                     WIEMVD"
     gene            10885..11517
                     /gene="pyrE"
                     /locus_tag="AC1PIV_000338"
     CDS             10885..11517
                     /gene="pyrE"
                     /locus_tag="AC1PIV_000338"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HIP6611391.1"
                     /translation="MTLATEIASHLLDIKAVHLRLEKPFTWASGIKSPIYTDNRITLS
                     YPETRNLIEDGFVQRIKEEFSEVEVIAGTATAGIPHGAIIADRMNLPFAYIRSKPKDH
                     GAGNQLEGRIVKGQKMVVVEDLISTGGSVLDAVAAAEREGADVIGVVAIFTYELPKAD
                     RNFDNAGVKLVTLSNYSELIKVAKVQGYINADGLNLLKKFRQNQETWQED"
     gene            11626..12552
                     /locus_tag="AC1PIV_000339"
     CDS             11626..12552
                     /locus_tag="AC1PIV_000339"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HIP6611392.1"
                     /translation="MISVIVPCFNEEEAIPYFYDAMEKVRKEMGEQFEYIFVNDGSKD
                     GTLTVLRQLSGQDRAVRYLSFSRNFGKEAALYAGLQAAQGELVTVMDVDLQDPPEMLM
                     EMKAMLDGNPDLDCVGTRRVSRDGEPPIRSFFAKLFYKLMNKISQVEVVDGARDFRLM
                     RRHMVDAILSVSEYNRFSKGIFAWVGFETEYLPYENVERVAGETSWSFWKLLSYSIEG
                     IINFSDTPLNIASYTGFFTFLLSLVLMVFVVFKTLVFGDPTIGWPSTICIILFLGGLQ
                     LMTIGILGKYLAKVFLETKKRPIYIVKEKSSN"
     gene            12562..13215
                     /locus_tag="AC1PIV_000340"
     CDS             12562..13215
                     /locus_tag="AC1PIV_000340"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HIP6611393.1"
                     /translation="MEHSAWHELIKAQLPEHYFGKINQFLDHVYAGGTIYPPREKVFA
                     AIQTTDLEEVKVVILGQDPYHGPGQAQGLSFSVPNSVPAPPSLQNILKELTDDIGVKQ
                     DHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIKVVNSLDQPVVYILWG
                     AYARKKKALITNPKHLVIESAHPSPLSAYRGFFGSKPFSQANAYLTSQGRTGIDWLR"
     gene            13255..14526
                     /locus_tag="AC1PIV_000341"
     CDS             13255..14526
                     /locus_tag="AC1PIV_000341"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HIP6611394.1"
                     /translation="MLLVKNGRVLDPQSGLDKVCDILMDGSKIVKIAESISEDVEQEV
                     IDATGLVVAPGLVDVHVHFREPGQTHKEDIHTGALSAAAGGFTSVVMMANTSPTISNI
                     ETLKEVLDSAKKEAIHIYSVATITDHFDGQNLTDFPALLEAGAVAFSDDGIPLTNAGV
                     VRKAMKLAKEQGCLISLHEEDPDLNGVLGLNEQVAEKHFHVCGATGVAEYSMVARDVM
                     IAYETGARVHIQHLSKAESVKVVEFVQGLGANVTAEVAPQHFSRTEELLLTKGANAKM
                     NPPLRLESDRLAVIDGLKSGVISVIATDHAPHHPDEKNVEDLTQAPSGMTGLETSLSL
                     GLTHLVEEGHLTLVQLLEKMTINPAKLYGLDAGYLAENGPADLVIFDPNANRLVTADF
                     ASKSANSPFVGDSLKGQVLYTIANGQIVFGK"
     gene            14657..16801
                     /gene="nt5e"
                     /locus_tag="AC1PIV_000342"
     CDS             14657..16801
                     /gene="nt5e"
                     /locus_tag="AC1PIV_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface ecto-5'-nucleotidase Nt5e"
                     /protein_id="HIP6611395.1"
                     /translation="MKKKKILLPVMSTLLLAPFVLAQQVQAAETTTAATTTNQPATTD
                     ATATVPATTDATATVPATSVENVATEETVVPAAEETVEAVIIHTNDVHGRILEEKNVI
                     GDAKAAAVIEEERAKVENTIVVDAGDAFQGLPISNSTKGEDRANIMNQVGYDAMAVGN
                     HEFDFGMDQAIKYKETLNFPLLSANTYVNGARVFEASTIVDKTPTVVGDEFVVIGVTT
                     PETATKTHPKNVEGVTFTDPVTEVNKVIDEVEARALADNRVYKNYIILAHLGVDSTTP
                     VEWRGSTLAEALSKNSKLAGKRVIVIDGHSHTVEATTYGDNVTYNQTGSYLNNIGKVT
                     LKSDKLLGEASLISAADTKNVTPNAKIAALVDEIKAKYEAENAQVVIENNPVELNGDR
                     SNVRVRETNLGNAVTDAIYAYGQTGFSNKTSLAVTNGGGLRATIAKDQPVTKGDIIAV
                     LPFGNIVSQITVTGQQIYDMFTKSLSSTLQVNPETGEMLLDENGMPLFEASGGFLHIS
                     GANVFYDPTLPVEERVLLIGILNPETGEYDALDLEKTYYLATNDFLAAGGDGYTMLGG
                     AREEGPSMDSVFAEYLKTADLSAYEVVNPYSRIIPVNSSIDTDEDGYPDFIEILLDTD
                     PENPASNPETVPAENTDSPSNQVQNTSATDKKAPVDSPKVGDKKTEVASPAKTTKAGV
                     LPNTGDQMNLTLSLFGLGLAGLAVAVGRRKEN"
     gene            16853..17500
                     /locus_tag="AC1PIV_000343"
     CDS             16853..17500
                     /locus_tag="AC1PIV_000343"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009146 - purine nucleoside triphosphate
                     catabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Maf family protein"
                     /protein_id="HIP6611396.1"
                     /translation="MQTVFQYQKEGDCEQISSYVLLSNSPRRKQLLGFLQPQIASVEV
                     DERGIEEHFMKQFATDDFLTRAAKTCCEISKAKSDMDLVTGHLYISADTIVVSDGQIF
                     NKPQDLTEAETMLRSYFGKSHHVVTSVCLRTRHSLDVFYTVAQIDFVDYYPALEEVIQ
                     SYIREKQPLDKAGAYGIQELDPRFVAGISGDIHTIIGLPVAEVSCRIFSEEGFEN"
     gene            17552..18040
                     /locus_tag="AC1PIV_000344"
     CDS             17552..18040
                     /locus_tag="AC1PIV_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HIP6611397.1"
                     /translation="MTVDIERYKQLAQQKQGEHRKFLANLKKKTPKNLDRIVQDIHAE
                     VFSEIDCTECANCCKTLGPLFTEADITRIAKHLRMKLPVFEDMYLRMDEDGDKVFQSM
                     PCPFLGGDNLCSIYDARPKACREFPHTDRKKIYQINNLTIKNTLICPAAYLFVEKLRE
                     RI"
     gene            18140..18991
                     /gene="ylqF"
                     /locus_tag="AC1PIV_000345"
     CDS             18140..18991
                     /gene="ylqF"
                     /locus_tag="AC1PIV_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002962311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HIP6611398.1"
                     /translation="MAIIQWFPGHMSKARRQVQENIKHVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLMILNKVDLADPVRTKEWQSYFEGQGIRTLAINSKEQATVKKVTDAAK
                     GLMKDKIERLRERGIQKETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKSNKDLEILDTPGILWPKFEDQEVGLKLALTGAIKDQLLPMDEVTIFGLDYFKANY
                     PERLQERFKGMDLEQETPELIMDWTKKLGFRDDYDRFYNLFVKDVRDGRLGTYTLDRV
                     SDLDGND"
     gene            18978..19751
                     /locus_tag="AC1PIV_000346"
     CDS             18978..19751
                     /locus_tag="AC1PIV_000346"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HIP6611399.1"
                     /translation="MATIKEVTALLAQVDSLDSPVWDQLAQDERAGVQAAIKKRRKEL
                     EKEAVEDARLEAMLFYEKSLYENGVEFIAGIDEVGRGPLAGPVVAAAVILPKGCKIRY
                     LNDSKKIPKSKHEAIYQEVMERAVAVGVGIKDAALIDEVNIYEATKLAMLEALGKLSQ
                     KPDHLLIDAMKLDTPIPQTSIIKGDANSLSIAAASIVAKVTRDKMMADYDKEFSGYGF
                     AKNAGYGTTEHLEGLNKLGITPIHRKTFEPIKSMVAGGN"
     gene            19754..20764
                     /locus_tag="AC1PIV_000347"
     CDS             19754..20764
                     /locus_tag="AC1PIV_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015445222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HIP6611400.1"
                     /translation="MTVFFWLFLAAIGLFALVYFWERRSIFISLFALNILVWALAWII
                     STGILEYNEILRLLAIAVAMVLFLALLSGPFVLLFTLYLNGFQILKREGVRFHNFLSM
                     GLAVALTFYLFIAPFVVQSLSAISFFNMVFVYVGFFVSYAIIISMLYTMSSFVNLVNF
                     FPGKLDYVVVLGAGLIGDKVTPLLASRIEKGIAIYQKQPGSKLIMSGGQGPDELIAEG
                     QAMANYALEKGVPAEDILIENQSTNTEENLKFSYALMKPGSRFALVTNYYHVFRALLL
                     ARQLRIKCIGYGAKTKFYFSLNAFIREFVGYVVMSRKAHLVFLSIVSALYLIGVIISL
                     MH"
     gene            complement(20797..21447)
                     /gene="trhA"
                     /locus_tag="AC1PIV_000348"
     CDS             complement(20797..21447)
                     /gene="trhA"
                     /locus_tag="AC1PIV_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0019835 - cytolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PAQR family membrane homeostasis protein TrhA"
                     /protein_id="HIP6611401.1"
                     /translation="MNPSLKLSLQLSFGEEVANSVTHAVGALLMLVLLPVTAIHSYQD
                     YNLTAVIGMSIFVISLFLMFLSSSIYHSMPYASTHKYILRIIDHSMIYIAIAGSYTPV
                     ALSLVGGWLGYLIVGLQWGLTIFGILYKIFAKKINEKFSLFLYLFMGWLVVFILPAIL
                     QKTGMAFGILMLAGGLSYTIGALFYAKKKPYFHMIWHLFILLASALQYIAIVYFML"
     gene            complement(21437..21988)
                     /locus_tag="AC1PIV_000349"
     CDS             complement(21437..21988)
                     /locus_tag="AC1PIV_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HIP6611402.1"
                     /translation="MKQTIPYWHELPDLDLYLDQVLLYVNQVVNSQESLEQKSLYSMK
                     INSSLGNEADDRTGVHQGKLITDNVDFRRVLTAAMINNYVKHKQLEKPVKKKYQKQQV
                     ARLIALTILKNVFSIQEISQTLNLLLQSSHSETLYNHFVDCMRNEENEETPDIIRYAC
                     QSVKLYYKTRQLTMELERSHHES"
     gene            complement(22096..23754)
                     /locus_tag="AC1PIV_000350"
     CDS             complement(22096..23754)
                     /locus_tag="AC1PIV_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HIP6611403.1"
                     /translation="MKIIIVGGVAGGMSAATRLRRLMENAEIIVFEKGPYVSFANCGL
                     PYYISGEIAEHDSLLLQTPESLKQRFNLDVRPFHEVISIDAEQQTVTVKTPTGELIES
                     YDKLILSPGAKPVIPNLSGIEEANNLFTLRNVPDLDKIMIKLDQIKSGHVVVIGAGFI
                     GLEMAENLALKGWKVMLVEQAPHVLPTFDLEMARYVEAELTNKGVEVITGQSVTAFHE
                     KGQVLELSNGQTLSSDVTILSVGVAPDSQLAKDAGVELGLRGGILVDQNYQTSQKNIY
                     AVGDAIVVKQEITGQDALISLASPANRQGRQVADVIAGLDRKNKGSIGTAIVKVFDLA
                     LAAASTGLSERAVQSLGYKHAVVHTTGKDHAGYYPGATDIVLKLIFSPTDGKIFGAQA
                     VGQKGIDKRIDVLATAIKAGLTIFDLPELELTYAPPFGSAKDPVNMIGYAAMNIAEGI
                     SQNIQWYQLDDELATGKVLLDVRNPGEVANGQFREFIHIPLDQLRERIGELDASKEYI
                     VSCHSGLRSYIAERILKENGFIVKNLDGAYSLYKMTLPKNIIQP"
     gene            complement(23751..24074)
                     /locus_tag="AC1PIV_000351"
     CDS             complement(23751..24074)
                     /locus_tag="AC1PIV_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HIP6611404.1"
                     /translation="MFKQLFSGMFSNSDSLPITDVEQAIQSSNAILLDVREVDEFASG
                     HIPQAINQPLSQLDQFKGDKTKNYLVICQSGMRSQRATEYLKSQGYQAINVKGGMNAW
                     TGGIA"
     gene            24181..24441
                     /locus_tag="AC1PIV_000352"
     CDS             24181..24441
                     /locus_tag="AC1PIV_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009909865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HIP6611405.1"
                     /translation="MNTDKKKMINRLKRAEGQLRGIQKMIEEDQECIDIVTQLSAVRS
                     SINSMMGMVIAQKVQDCITHPSENPEEQEARLAQAINLIIKK"
     gene            24452..25009
                     /locus_tag="AC1PIV_000353"
     CDS             24452..25009
                     /locus_tag="AC1PIV_000353"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014917244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016407 - acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HIP6611406.1"
                     /translation="MSTEKEKMIAGQFYMAADAELRKMRTFARQQMKKFNEELDGKAR
                     SERLKSWFGTTGQRIYMEPNFYCDYDSNIHVGEDFYANFNCTMLDVCPITIGKNAMLG
                     PNVQLLTPLHPLDPDERNSGLEYGSPITIGDNFWAGGGVTILPGVTLGNNVVGGAGSV
                     VTKSFGDNVVLAGNPARVIKEIPKK"
     gene            25068..25910
                     /gene="dprA"
                     /locus_tag="AC1PIV_000354"
     CDS             25068..25910
                     /gene="dprA"
                     /locus_tag="AC1PIV_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HIP6611407.1"
                     /translation="MNNFELFKWKKAGLTNLNVNKVLAYQEKHGKKLTLRNVAVVSEC
                     KNPVLFMENYKNLDTKACREEFNKYPSFSILDDIYPLALKQIYNPPVLLFYQGDLELL
                     EKLKLAVVGTRNASKNGIQSVQKIIKELSNRFVIVSGLARGIDTAAHIASLKNGGQTI
                     AVIGTGLDNIYPKENKDLQTYIGKHHLVLTEYEAGAQPLKYHFPERNRIIAGLVEGLV
                     VCEAKMRSGSLITCERALEEGREVYAIPGSIMDGKSDGCHHLIQEGAKCVTSGLDIIS
                     EYQF"
     gene            26003..28096
                     /gene="topA"
                     /locus_tag="AC1PIV_000355"
     CDS             26003..28096
                     /gene="topA"
                     /locus_tag="AC1PIV_000355"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HIP6611408.1"
                     /translation="MATKTVSKKKTTTKKNLVIVESPAKAKTIEKYLGKNYKVVASVG
                     HIRDLKKSSMSIDFDNNYAPEYINIRGKGPLINSLKKEAKNAKQVFLASDPDREGEAI
                     SWHLAHILGLDANDKNRVVFNEITKDAVKNAFQEPRAINHDLVDAQQARRVLDRIVGY
                     SISPILWKKVKKGLSAGRVQSVALKLIIDRENEISNFKPEEYWTIDATFKKGSKKFQA
                     SFYGIDGKKTKIENNEQVKEILARLDGDDFLVEQVERKERKRNAPLPYTTSTMQMDAA
                     KKINFRTRKTMMVAQQLYEGVSLGTGGTQGLITYMRTDSTRISPVAQAQAADFITERF
                     GATYSKHGNKVKNASGAQDAHEAIRPSNVNLTPESIAKYLDKDQLRLYTLIWNRFVAS
                     QMAAAVFDTMSVRLGQNGVIFAANGSQVKFDGYMAVYNDSDKNKMLPDMEQGDTVVRT
                     STNPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVKLAAKRFEPT
                     ELGEIVNKLIVEFFPDIVNVKFTADMEQKLDDVEIGKEQWQKVIDGFYQPFKVELFKA
                     EEQMEKIQIKDEPAGFDCDVCGHEMVIKLGRFGKFYACSNFPDCRNTKQITKEIGVTC
                     PVCQQGQVIERKSKRNRLFYGCDRYPECEFTSWDKPVGRACPKCDHYLVEKKVRGGGK
                     QVVCPNGDYEEDKIK"
     misc_feature    28512..28646
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            28673..29167
                     /gene="rplJ"
                     /locus_tag="AC1PIV_000356"
     CDS             28673..29167
                     /gene="rplJ"
                     /locus_tag="AC1PIV_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HIP6611409.1"
                     /translation="MSEAIIAKKAELVNAVAEQMKAATSIVVVDARGLTVEQDTVLRR
                     NLRGAEVEYKVIKNSILRRAAEQAGLEGLAELFVGPSAVAFSNDAVAPAKTIYDFAKT
                     ADALEIKGGAVEGKVSSKEEIEALATLPNREGMLSMLLSVLQAPVRNVAYAVKAVAEK
                     EDAA"
     gene            29233..29598
                     /gene="rplL"
                     /locus_tag="AC1PIV_000357"
     CDS             29233..29598
                     /gene="rplL"
                     /locus_tag="AC1PIV_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HIP6611410.1"
                     /translation="MALNIENIIAEIKEATILELNDLVKAIEEEFGVTAAAPVAVAAA
                     GGAAEEAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPAMVKEGVATA
                     EAEEIKAKLEEAGASVTLK"
     gene            29723..30472
                     /locus_tag="AC1PIV_000358"
     CDS             29723..30472
                     /locus_tag="AC1PIV_000358"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HIP6611411.1"
                     /translation="MKSYKNYIFDFYGTLVDIRTDENKLEVWNQLTQIYNAFGCSYRP
                     RQLKNAYHRFVEEAESSLAETVSYQYVEIDLETIFIRLLTDAPNENQSTNKPTDLETF
                     GQVVATIFRVLSREKLEAYENTLTSLQTLKDREVRLFILSNAQRIFTQAEIEQTGCAD
                     LMEKIYISSDFKMKKPEPAFLQLVLEENNLDVEETVMVGNDLTSDIAIAHELGMDSIL
                     LNTFPYSQEEIDSYRRLGWNFEVVGDIAELL"
     gene            30668..32002
                     /gene="trmFO"
                     /locus_tag="AC1PIV_000359"
     CDS             30668..32002
                     /gene="trmFO"
                     /locus_tag="AC1PIV_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HIP6611412.1"
                     /translation="MSQTHINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKPTPQHK
                     TDKFAELVCSNSFRGDSLTNAVGLLKEEMRRLDSIIMRAGEAHRVPAGGAMAMDRENF
                     SQAVTDEIHNHPLIEVIRGEITEIPEDAITVIATGPLTSDALAEKIHALNGGDGFYFY
                     DAAAPIVDSSTINMDLVYLKSRYDKGEAAYLNAPMNKEQFNAFYEALISAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPEDYKGPRDGEYKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRIFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     FATKKNPNLFFAGQMTGVEGYVESAASGLVAGINAVRRFHGEEPVIFPQTTAIGALPF
                     YITHTESKHFQPMNVNFGIIKELDGPRIRDKKERYEAIAERSLKDLEEFLTV"
     gene            32079..32915
                     /locus_tag="AC1PIV_000360"
     CDS             32079..32915
                     /locus_tag="AC1PIV_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HIP6611413.1"
                     /translation="MIKEFNATVRYLESVLESEIDEREFLRISGYSVPMFSRLFSILT
                     DMSLSEYVRLRKLTRAAMDIREGQAKIIDIALKYGYESSDSFAFAFKQFHQISPSQVR
                     KGLPFKVLLPLQLSLTIQGGKEMDVRIEKKAGFTVAGLLRTAISNEVCPQVWEDLFKN
                     HTYEELAALGSGQSFGVCTLAQADETINYMAAYDVTDSEKATKLGLELLDVHEADYAI
                     FTLTGPVPQSIHAGWRYALETFFPEHGYRHSGAPDFEYYFEGDMSSPDYQMELWIPIV
                     KA"
     gene            32980..33984
                     /locus_tag="AC1PIV_000361"
     CDS             32980..33984
                     /locus_tag="AC1PIV_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0036297 - interstrand cross-link repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA glycosylase AlkZ-like family protein"
                     /protein_id="HIP6611414.1"
                     /translation="MHHNTWKGIILQKQGLLNPQSVQQICQNLNGLQAQFQPYVHVGF
                     RNRMTAEDFHEGSWQEELTRQWSIRRTVHAYLESEIPLYIHEGRLVSTDYLKTEGRDG
                     FSPQTKQKYHHLILEALEQGPMTREDLKVLCREEKMTQKEEKLVFNAWGGLFRYMVER
                     GEVYQEYGAKRFHRLTDFQPLSREKAELEIARRYFSGFGPVSLADARYYFKENKSTIL
                     EWMAQLDLKTIQVAGEERFYLGVLDEADLPQCLFVAGFDQLLLGYEKKNNPFFDPKYI
                     RNIYTLTGIVKPVVFYKGRFVATWKRDKGTILLDIFESITQKEEKELDYYRQMYEKIL
                     "
     gene            34098..34925
                     /locus_tag="AC1PIV_000362"
     CDS             34098..34925
                     /locus_tag="AC1PIV_000362"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HIP6611415.1"
                     /translation="MNKSYFYLDMRTHELDVPFTERKRRVRVLLPKGYAENTEETYPV
                     VYFHDGQNVLYSKEAFSGHSWKVIPTIKRNPDIAKMIVVAIDNDGADRMHEYAAWKFS
                     EMGIPGVQFGGKGTLYAEFVMDVVKPFIDQEYRTKSDKVHTAMIGSSLGGNITQFMGL
                     AYQNQIGCLGVFSSANWLHQDAFDRYIERQQLDSEQRVYIYVGTEEADDTDKTLMAGN
                     IKQAYINSSLTYYRQLIAGGVDLDNIALEVVSGAVHNEEAWALYLPACLRFLSEHWS"
     gene            34956..35702
                     /locus_tag="AC1PIV_000363"
     CDS             34956..35702
                     /locus_tag="AC1PIV_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002909732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HIP6611416.1"
                     /translation="MHVEFLSHWSGNLGREMNLNRYGHVGIPVVVFASSGGSYNEYAD
                     FGMIEACRGSIEAGQVQFFTLTSYDSESWLADWKSIHDKAEAHRAYERYVIEEAIPFI
                     KHKTGWFDGMMTTGCSMGAYHALNFFLQHPDVFTKVIALSGVYDARFFNNNQDYGNDD
                     VVYQNSPSDYIWNQNDGWFIDKYRQADIIVCTGLGDWEQDGLDSFYNLKRAFEEKSIP
                     AWFDTWGTDVAHDWVWWRKQMPFFLHSIGL"
     gene            35720..36886
                     /locus_tag="AC1PIV_000364"
     CDS             35720..36886
                     /locus_tag="AC1PIV_000364"
                     /EC_number="6.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HIP6611417.1"
                     /translation="MNYLVISPFYPENFQPFTIELAKKEGVTVLGIGQEPYDQLPEEL
                     RNALTEYFRVENLENLDEVKRAAAFLIYKHGPIDRVESHNEYWLENDAALREQFNIFG
                     AKPKHLKKTKFKSEMKKYFKKAGVPVVPGVVVKSERDFGRALKNVGFPMIAKPDNGVG
                     ASGAFKIENKEDFDRFVETWDGATIYFLEKFVNSSIITTYDGLLDYEGNVVFETGLTY
                     VHTPFELMQTKKDNAYFIEKELDFKLVEYGRAIIKAFGMRERFFHIEFFKDGDDYIAI
                     EYNNRMAGGFTVEAYNYAHSIDLFRDYANVATGGTVEERRFEPQYCLVATRRDTTEYV
                     HSADDIHQTFAGKIKTVKRMPDAFAELQGNDAYLLVTESKKELDEMIAYIGLTK"
     gene            37026..37166
                     /locus_tag="AC1PIV_000365"
     CDS             37026..37166
                     /locus_tag="AC1PIV_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611418.1"
                     /translation="MSFKFLQAKRIEEKVFSEKEKAELMEQALFLEELAHNLQSMRFM
                     AY"
     gene            37179..37556
                     /locus_tag="AC1PIV_000366"
     CDS             37179..37556
                     /locus_tag="AC1PIV_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NisI/SpaI family lantibiotic immunity
                     lipoprotein"
                     /protein_id="HIP6611419.1"
                     /translation="MKKKVISMLALGSIILTACSSSSAGFSFDEGYQTFHYKGKVYAV
                     SKQEVAEDSIQGTEVQFMEWPVVKEEGAVKKTVSLNNLYVTTNKEWAIGVQDGYYKVD
                     LEENVAESDRIDYQSVLENVDFT"
     gene            37577..38479
                     /locus_tag="AC1PIV_000367"
     CDS             37577..38479
                     /locus_tag="AC1PIV_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002943278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIP6611420.1"
                     /translation="MLLEINHLKKVYKDVTTVDIEKITVREGEIYGFLGPNGAGKTTT
                     MKMILSLVTPTSGEIFINKKDIRNDKKYLNQIGSMIEEPSYYPNLTGYENLLVFQKMV
                     GFDKNNIRPTLELVGLADEKNRKKLVKAYSLGMKQRLALAFALVKKPKILLLDEPTNG
                     LDPAGIHEIRELIVQLAKEKGLTVFISSHILPEIEHIADRVGIINHGRLVYEGEIEAI
                     KSNTWIEIGGDFSQKNIVQTLVELGTVEILSASESQVTLRDLDNDRLADLVSYLIENG
                     YRIFRVVRESETLEDIFLNLTKEA"
     gene            38481..39227
                     /locus_tag="AC1PIV_000368"
     CDS             38481..39227
                     /locus_tag="AC1PIV_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002943276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIP6611421.1"
                     /translation="MNGVYIEWLKSRRTKSISIVIILMLVATLWNIATFISAFSSHPE
                     LRMAGTLFSNQNVNLLMFPIAVCVFASRIVGNEHEGQTFKLQIANGQSLTAIFRDKFF
                     FMLVSFVIMSAIEIMIIYLFGTQAGISISLQIIGIQFIGQILAIFSLICLYLTLAMIL
                     EKQGILLALGLLGGFLGIILNPKSYGFTSLLNPITGSGSLAPYKYQFLGDGTITYNLD
                     SQLLEKIVCYAIYCLILYLLAVLILRKKGN"
     gene            39229..>39838
                     /locus_tag="AC1PIV_000369"
     CDS             39229..>39838
                     /locus_tag="AC1PIV_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002943275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIP6611422.1"
                     /translation="MKDYFLAEWTKTRKIQLLVIGIAFLSFSSMIGLGIYFANRDVLI
                     DGTQSLVLWGQLTFYNSTLLYPPMLAIIAGLLLVPEFERKTLDMLKANQVSMRKLYLG
                     KLMSSFLLILPIQLLLLLIFIVAAKIDGISFDLSLATHVKWIALSLLSSFPIITLQSY
                     ITVKTRNFSKGVGVATIGSMLNFVLIFINESFTKFFPYSQPMI"
BASE COUNT        11908 a         7472 c         8840 g        11618 t
ORIGIN      
        1 agaaatatga aaaaaatctt ggcattagca gcaacagttt tagctggact gacattggca
       61 gcttgttctt cgacgtcatc acaatccgca ttagataaaa ttaaagaaaa aggaacatta
      121 gtagtggcaa ctagtccaga ctatgctcca ttcgagtttc aggcactagt tgatggaaag
      181 aatgaagttg ttggtgcaga tattatgttg gctcaaaaaa tagccgacga acttggggtc
      241 aagcttgaag tttcagcaat gagttttgac aatgtattgt ctagcgttca gaatggcaaa
      301 gctgatattg caattgctgg tctatcttat tcggaagagc gtgcaaaagt ttttgatttc
      361 tctgaaagtt actatcaaat ttctgatgta ttacttatca aaaaagatag cgccaattca
      421 ctcacttcaa ttgatgctat gagcgggaaa actctcgcgg tacaaaaggg ttcaacacaa
      481 gaatcctatg cacaggaaaa cattagtcaa gctaacctaa tttctttaac cttgatgggt
      541 gaagctgtaa atgagctcaa atcaggaaaa gttgatgcta ttttaatgga ttctccagtt
      601 gctgctggtt atgtttcaca gaattcagat ttagccgttg catccgttga atttccaacg
      661 attgatgaga attcgaaagt cattgctttg ccaaaaggta gtacagaact aaaaactgcg
      721 atagacaagg ttatcgcaga agtaaaagca agtggtgagt ttgatacttt ccttgagaaa
      781 gctgcaacat atacaagtgt tgaataagag aaatgaacaa tcatcggaaa cggtggttgt
      841 ttttgcatgc aaaaaagaat ggagtaagtg agccacacac caaaagttag acagaaaatt
      901 tgggtcggtt caatactcca ttttttatag ataattattt cacacgctct agataaaaac
      961 tggtcaaacg tggtacagta attctggctc cattttcatc gggatagagg ctaaatgtgt
     1021 ccattggaat agcattagat gagaagacaa gtttatattc gctgtcagct ggcaaatcca
     1081 agtgtacatc aaatagttct tgatcattaa agttatgaat agtcaagatt tcttgcacat
     1141 cactagtgcg agaaaaagca tacaggcttg cttcttcatc tatttttacc caattaaatc
     1201 ctttttcata ggcttggtag tcatatttcc agaaagcatc atgttcttta tagaaagtag
     1261 atagtgtttt catcatttga tagaaagaat ggtggattgg aaattgtagc agtccccagt
     1321 ccatttctgt atattcgtgc cattcacgga tgtgacccca ttcatttccc atgaagagta
     1381 atttctttcc aggatgggca aagtaaaagc tgtagtagac tcgagccaga tggaacttat
     1441 cttcgtagtc gccattcatc ttctcgataa tggagtgttt cccatgaaca acttcgtcgt
     1501 gcgaaagtgg tagtaagaat tgctcgtttt ggttatagta cataccaaaa gtgatttcat
     1561 ttgagtgata ttttcgataa atagcagggc gttccacgaa ttttagtgta tcattcatcc
     1621 agcccagatc ccatttcata tcaaatccaa taccgccatc ttctagagga tgtgtgactt
     1681 tagggaagct tgaagagtct tcagcaatca tcaagactcc cttatagtcg gtatggacca
     1741 tggcattgac acgtttgata aagtcaattg cggcatgatt tatcttatct tcatctgttt
     1801 caccacgcca atagaggaga taagatagtg catcaacacg gatgccatca aaatggaaat
     1861 attccaacca gtattttaaa ttagaaagaa ggaaagaacg agtcagtcct tttccaaggt
     1921 caaaattagc agtcccccac tggtgatttt cacggtcttg ttcgtaggag tattcgtata
     1981 gccaactacc atcaaactgg tagagcccat gagcatcttt acagaaatga agtggtaccc
     2041 agtcaagaat cactccgatt cctgcttggt gacattggtc aactaaatac ttaagttcat
     2101 ctggcttgcc atagcgacta gttggactgt agtagcctgt tacctgatag ccccaagacg
     2161 catcgagagg atgctcggta attggcaata actcaatatg tgtgtagtta ttttccttga
     2221 tatgttcgat gagaagtgga gtaatttcct tataactatt gaaagcttct acaggagctc
     2281 ctccttcatt tttattagca aatttttgct tccacgaacc taagtgcacc tcgtagatgg
     2341 atactggctg ttctttaaaa tcatagttaa cacgattata catccagatg tcatctttga
     2401 atttataacg cgaattgtag gttgtagagg cagtgtctgg acgaacttgg ctgaaaaatg
     2461 cataagggtc agccttatat atttcacgcc catcgtgtgt gataatcagg tatttataat
     2521 cttcaaggga ttttaatccg tctacataaa gttgaaatac tccatcaatt tcacgctcca
     2581 tagagtgact gcgttgccac tcgttaaagt tgccaactaa gaatacttct ctggcatttg
     2641 gggcatagac acgaaattgg gttccgataa ttttgtttcg ttcttttata atatgagcac
     2701 ccattttttc gtaaagagtg gtatgctcac cagtattcat ataatataaa tctaggtcag
     2761 taaattctgt catagcaatc tccattgccg aaaaggagtg gactagggtc ccactccgat
     2821 tcagtatatt ttttcatctt atttcctaac cactaatttc acggtagagc cagatgtatt
     2881 tctctgccga agctgtccaa ctaaaatcac gcttcatagc ttgttcaacc atggcatacc
     2941 agtcatcggg acggtcatag taggtttgaa gggctaaatc atagacttgt cgcatattgt
     3001 aagcgtcacg ccctccaaag ctaaagccag ttccttcctt ggtagacata ttgtatggtg
     3061 ctacagtatc aaccaagcca cctgtttcac gcactagagg gagtgttccg tagtgcattg
     3121 aaatcaactg gctaatgccg catggttcaa acatagaagg cataaggaag agatcacttg
     3181 ctgcataaat ttggtgggca agtggttcat tgtaaccacg gtagaatgca aatttatcag
     3241 gataagcatg tttaaagtga ttaaaggcat tttcaatgtc ttcctcacca ttgcctaaga
     3301 taacaaattg gacatgggct tgaagaagat ggccaagtac ctcggtcaag aggtagaacc
     3361 ctttttgcca tgtcaaacga gagacgatac ctatcaatag gacattctca tcttgtggaa
     3421 gggcaaattg tgattgcagg gccagtttat tagccttttt actttcaatc gtttcaagac
     3481 tataatttct cacaaggtac tgatctgttt gactatccca actgtcatag tcgataccat
     3541 tgacaatacc aaccaagtca tatttgcgca actctagtac atgttgcatg ttttcgccga
     3601 attcttccgt taggatttcg cgagcataag tttcagaaac tgtagtaacc ttgtcagcgt
     3661 ataggatacc cagcttcatg aagctgatac attcatcatg aaaacgtgca ataccatcca
     3721 aatagtagct atagtccatg ccaagcgctg accaaagtgc ttgtttgtga aaaataccct
     3781 gaaaagccaa gttatgaata gtgaatacat gcttgatatt gcggaattct tcgcggtagc
     3841 tatagaaagt acggcaaagg aatggaaggg cagcagtgtg ccagtcatgt gtgtgcatga
     3901 catccgggaa gaaatgaagt gcttctaaca gacgacatgt agcatgttgg aaatagccaa
     3961 aacgcatggc atcatcgtcg tatccatata gttcatcgcg ttcaaagaaa tcgcggtgtt
     4021 caataaaata gaatgttact ccatcaacaa cctgactgta aacatttgcc atagattgga
     4081 tgtcgccagc ccgcacatca aaacttgata cgtaatcgaa atcagagtga ttgtttactg
     4141 caattttttt gtagagtggt agaacgactc ggacatctaa accctgtttt accaattctt
     4201 ttggtaaaga gccaataaca tcagccaatc cgccagtctt gatgaatgga agtccctcgg
     4261 atgctacaaa gagaacagat ttttttgtca tgttagctcc taaatgattt ggtgtggttt
     4321 caagtatgaa ggcgaagttt cgcttccctt gatgtcaatt gggtgaataa ttttagttgc
     4381 tttatcgata attgcatttt caatattcgc cccgctcttg attgtcacgc cattgagaat
     4441 gattgagttt ttgataacaa caccttcttc aatgataaca tcgcggtcaa tgactgaatt
     4501 ttcgacttga ccattgatat tcgctccatt tgaaattagg ctacgtttga cctctgccaa
     4561 tggaccatat aaacatggtg agctatcact tgtttgagta tggattggcc aatcatgttt
     4621 gaagaggagt ttgcgggtat cttggtcaat caattcaatt tgagtattga agtaggaagc
     4681 tgtcgtattg atacatgcga cataatcacg atgtgcatag cccataatct tgtactggtc
     4741 aactgtatca cgtaaaatat cttttaacca gtagagagac gacactttgt tagcacgttt
     4801 aatcaagtcg ataaatgtag tccgtttcat aatgtaggct tcaagggaaa cgggacggtt
     4861 tttatattta ccatggtttt cctcaaaagc tacgacacga cggtcttcac caaatttgag
     4921 agtttgacaa ccgatgaaat tttctttagc atctgaaacg tttttataaa gaacggtaat
     4981 atcagcatcc gttgcgatat ggtcatccat gacttttgaa aaatcctggc tatagatgaa
     5041 gtaagatgga gcaactagca cataatcttt tgtagaattt tcgatgtagt ggatgttttc
     5101 tgtgaaggca ttaatatcgt gacgatagac actatttggg tctgttgcgc tattgagcaa
     5161 gcgaagggta ccgcgtttgc tgttgatatt atagtgtttc cctgtaccaa cgtgctgaat
     5221 tgttgaacgc atttcggcag gcatgtatac ttagaattct gtaattccag agtttgacat
     5281 attggataga gcaaagtcaa ttaggcgata acgacctaag aaaccgaaag cttgtacgcc
     5341 acggtgcttc atcacgtcac caaaatgtac gttgtttcct tcaatattta caattccgag
     5401 agtatttctt agcatagcag tcctttctta cttggtcaca ttcttgtcaa tcaagaggat
     5461 atggtcgatg tctcctgtga gtttaactcc gtcggcaatt ttaatatttt cagcgacgat
     5521 gacgtagtca agttcaacac cttcgccgat aatagcacca ggtaggatga cagaattttt
     5581 tactacggca ttttggttga cttgcacatc tgttgaaata acagaatgtt ctacagtacc
     5641 atcgatgatt gcccctttat caatataggc agatttaacc gttgcagttg caccaatgac
     5701 ttgggcagga gatcccttat cctctgaata gattctccat gagcggtcag aaaggtccaa
     5761 atctccagcg tgatcaatca agtccatatt ggattcccag aggctgttaa cggtacctac
     5821 gtctttccaa taaccacgga atggatgggc aatgagagtg cgaccatctt ctaagtattt
     5881 cggaatgatg tcgtgcccaa aatcgtgaga tgaagtgtcc aatttgtcat cttcttgaag
     5941 gtactttttc aaggtcttcc aagtgaagat atagataccc attgatgcta aattgctctt
     6001 aggattttct ggtttttctt caaattcttc aatacggtaa tcttcgtccg tattcatgat
     6061 accaaaacgt gaagcttctt tgattggaac ttcgataacc gcaatcgtgg catctgcttt
     6121 tttctgaata tgtgtatcaa ggagtttgtc gtagttcatc ttatagatgt ggtcaccaga
     6181 caaaatcaat acgtgctctg gatcgtgaag atcaatgaaa tcaatgttct gtgtaatagc
     6241 gtcggctgta cctttgtaaa gtccgaaacc ttcgattttt tcactcggtg gtaatacaaa
     6301 gacgccagat ccttgtacat caagtcccca acgttgagac tgtgcaacgt atgagttcaa
     6361 gagaacaggc tcatactgag tcaaaactcc gacaatatca atacctgagt tggcacagtt
     6421 actgagagga aagtcaataa tgcggtactt tccgccaaat gcgaccgctg gtttggcgac
     6481 tttttttgtc aacccttcta gacgtgttcc acgtccacca gcaagaatca tagctaacat
     6541 tttattttga gccatctaac cactccttaa tatatatgat acatgtatta tagcatagag
     6601 tataaaaaaa tgaaagcgtt tccttaaaga aaagtgaatt attttcattt ttcttttcaa
     6661 cgtctttcat aaatgtatca taacatattg tattttgttt gtctatataa agtggtattt
     6721 atttttggtc gaattttacc tcttcaagta ggtaattgat gaatttttct cccatgtcgg
     6781 acagcaatgc cttttcgtgt tgaatataga ccaattcgat ttcatcatca aattccagag
     6841 gaattgatac aatattatct ccgttaaggt ttgaattgag gatacctgtt gcgattgtat
     6901 agccatctag accgattaag agattgaaga gtgtggcacg gtcagatacg acaatcgatt
     6961 ttttatggtg ttcctgggct agaatttctt ctgcaaagta gaaggagttg tgaatacctt
     7021 gctcatagct gagatagggg aaatctacca aatcatcgag agtgattgac tttctttgtg
     7081 ccaaaggatt ggttttgctg acaaatacat gtggtttggc agtgaagaga gttgtatagg
     7141 atagtcgatt gtcatccaac agtttcagca gaacatcacg gttgaaatgg ttgaggaaaa
     7201 gcactccgat ttctgagcga aaattcttaa cgtcatcaat gatttcccag gtccgtgttt
     7261 cacgtaggaa gagttcataa tcttccattt cagtttcttt caaaagtgag acaaaggcgt
     7321 tgacgacaaa ggcatagtgt tgagaagaga cgctaaatag ttggcgtttt gcattaggat
     7381 ttttatagcg atcttctaaa agctctgtct gttcaacaat ttgacgagcg taggaaagaa
     7441 actccatgcc atcctttgtc agggtaatgc ccttagaatt acggaaaaag attttaattt
     7501 tcatttcttt ttccaggtct cgtacagcgt tggaaaggct gggttgggta atgaagagtt
     7561 gtttggcagc ctcattcata ctgcctgttt ctgcaatttt gataatatag tataattgtt
     7621 ggattctcat acctccattg taacatgatt tgacaaatta ttctaaaaaa tgtataatgc
     7681 tgaaaatata tcctttaact gagtccagag aggcgaagaa gggaacgtga taaatagggc
     7741 aaatactgcc ttcttttcgt gtaaccttgc tagccagcaa ggttttttct ctatatcgac
     7801 tttcttgttt tctgtgtcat tgttatatag aataggagaa aagatgattt taaaagaaca
     7861 gatgttactg gtggaccaag tccaactagc gccacgaatt tttgctatga ccttgcaggg
     7921 tgatatggtc caagatatga aaatggggca gtttatccat attcgtgtcc cagatgattc
     7981 catgctcttg cggagaccaa tatctatttc cgagattgat cggaataagt ctcaatgtcg
     8041 gattatttac cgagtggaag gtcaagggac ggaagtcttt tcgaaaatga cggtcgggca
     8101 gtatttggat gttatgggac cgcttgggaa agagtttgaa gtagactttc tcaaagaagg
     8161 tgaccgcatt ctcatcattg gcggaggaat cggtgttcct cccttggtgg aagtagccaa
     8221 acaggctgcg ttccgtggtg tcaatgtcac gtcagtcatt ggctttgcca ccaaagaggc
     8281 cgtcattttg gaagaggagc tggcaagtta tgggatggtc tatgtcacaa cggatgatgg
     8341 ttcctatggg cgtaagggga atgttgcaac ggtcgttgaa gagctgacaa acgagtttgc
     8401 agccatttat tcctgtggag cacctgctat gatgaactat gttgaccaac gctttcagga
     8461 acatcctcat gcctacattt cactggaggc taggatggct tgcgggatgg gggcgtgcta
     8521 tgcctgtgtt gtcaaaccca aagagggaca agaacacgag aacaagcgtg tctgcaagga
     8581 aggtccagtc tttgcgacag gtagtctaat tttgtaggag gttgaaatga caaaacgatt
     8641 agcgatttcc ttaccaggct tggacttgaa aaatcccatc attccagcct ctggctgctt
     8701 cggttttggt caggaatatg cagattatta tgaccttaac cagcttggat ctattatgat
     8761 taaggcgact acccgtcatc ctcgttatgg caatgcgact ccccgtgtag ccgagacacc
     8821 agcaggtatg ctcaatgcca ttggacttca aaatccgggt gttgaggcgg tcttatccga
     8881 aaaattacca tggttagagc aacatttccc agatttgccc atcattgcca atgtggctgg
     8941 tttttccaat gaggaatatg cctatgtgtc agggaaaatt tcaaaggctc caaacgtaaa
     9001 agctatcgag ctgaacattt cctgtcccaa tgtggaccac ggaaataatg gtctcttgat
     9061 tggacaggtg ccagaattag cctatcaagc agtaaaagca gcagtcgaag cctcatctgt
     9121 acctgtttac gttaagctga caccaagtgt ggcagacata accctgttgg ccaaggctgc
     9181 tgaggctgct ggagcgactg gcttgacgat gataaatacc ttggttggta tgcgattcaa
     9241 tctcaaaact cgacaaccaa tcttggcaaa tggtacagga ggaatgtcag gtccagcagt
     9301 ttttccggtt gctctcaaac tcattcgtca ggttgctcag atgactgatt taccgattat
     9361 tggtatgggt ggtgtggata cggcggacaa ggctatagag atgatggttg caggagcttc
     9421 agccattggg gtagggacag ccaactttac agacccattt gcttgtccaa agattattca
     9481 agacttgcca aaacgcatgg aagtttatgg tattgatagt ttggaaggtt tacgccgaga
     9541 aatcagatat agcttgggta agcgttgaca aaggtaaaat aaaagagtaa tataaagaaa
     9601 atatctcctt taactaagtc cagagaggct aggaaggtgt catgtaatat gcttgaaagg
     9661 tgattttcaa gctgaattcg tgcacatccc tgaccgattt ggcagggatt tttgtgtaaa
     9721 tgaaaggatt ttatgaaaga aacaagacca attattgccc ttgactttgc aggtaaagaa
     9781 gaagttcagt cttttctgga acagttccca ccagatgaga aactctatgt aaaggttgga
     9841 atggagttgt attatgcgga gggaccaggt attatcaatt atttgaaaga ctgcggtcac
     9901 agtatttttc tagatttgaa actgcatgat attcctaata ccgtcgagtc tgctatgaaa
     9961 gtcttggcaa aactcggtgt ggatatgacc aacgttcacg ctgctggtgg tgttgagatg
    10021 atgcgggcag cacgaagggg attgggtaag gatgctgttt taatagcggt cactcagttg
    10081 acctctacct cagaagagca gatgaggacg gaccagaata tacagactag tttgcaggaa
    10141 gcagttgttc attatgctca aagagcacaa gaagctggtc ttgatggggt ggtttgttca
    10201 gctcatgagg tggctttgat taaagatgct acaagttctg attttgtgtg cctgacgcca
    10261 gggattcgtc cgactggcgg tgaagtaggc gatcagaaac gagttatgac accagcagat
    10321 gctgctcgaa tcggtagtga ttacattgtg gtaggtcgcc cgattacaaa atcagaacat
    10381 ccttaccaga cctatttgtc tattaaagag gagtggaatc gtggataaga tttatcaggt
    10441 tataatcgat agacctctcg ggtatattga taaatttggc aaccagtatc caatcaatta
    10501 cggctatgtt ccaaatctat tggctggaga tggtgaagag caagatgttt acatcatttc
    10561 caaagctgtt cggcagccct tgacagcttt cgaggggaaa ttggtcgcga ttatacatcg
    10621 cagagatgat atcgaggata aatgggttct gacaggtctt gatgaaaaac ttaccgtgac
    10681 agaaataaaa gagaaaacca attttattga ccagtatttt gattcatgga ttgaaatggt
    10741 ggactaggag aagtctgtaa gaattcaaca gggataaata tagttttttg tagggttcat
    10801 agattgaacc agtactttag gagtgacagg ctattcggcg ggatggtcat gttggaatgg
    10861 tacgcattta gaaggaggtc tattatgaca ctagcaacag aaatcgcatc acacttattg
    10921 gatattaagg cagttcatct gcgtctagaa aagccattta catgggcatc aggtatcaaa
    10981 tcccctatct atacagataa tcgtattaca ctatcttatc ctgaaactcg aaatttgatt
    11041 gaagatggct ttgtccaacg tattaaagaa gaattttctg aggttgaggt gattgccgga
    11101 actgccacag caggtattcc tcatggtgct atcattgcag atcggatgaa tttgccattt
    11161 gcttatatcc gtagcaaacc aaaagatcat ggtgcaggga atcaattaga gggtcgcatc
    11221 gtcaagggac aaaaaatggt tgtcgttgaa gacctgattt ctactggagg gtctgttcta
    11281 gatgccgtag cagcagctga gcgtgaaggc gctgacgtta ttggtgttgt ggcaatcttt
    11341 acctatgaat tgccaaaggc agatcgtaat tttgataatg ctggcgtgaa attggtgacg
    11401 cttagcaatt attcagagtt aatcaaggtc gcaaaagtac agggatatat caatgcagat
    11461 ggtttgaatc tgcttaaaaa gttccgtcaa aatcaagaaa cttggcagga agactagatt
    11521 taaaacgagc ccacgcacga tttctgggaa cttatcctgt aaaatggtat aatagtctct
    11581 aacgtatttt gagaatacaa taattgaccg tatgaggaga agaacatgat ttcagttatc
    11641 gtgccttgtt ttaatgaaga agaggcaatt ccctattttt acgatgctat ggagaaagtt
    11701 cgtaaggaga tgggggaaca atttgagtat atttttgtca atgatggttc aaaggatggg
    11761 acattaacgg ttttacgcca attgtctggt caagaccgag ctgttcgcta tctttccttt
    11821 tcaaggaatt tcgggaaaga agctgctctc tatgcaggtc tacaagctgc gcaaggtgag
    11881 ctagtgacag tcatggatgt tgatttacaa gatccacctg aaatgttgat ggaaatgaag
    11941 gctatgttgg atggaaatcc agatttagat tgcgttggaa cccgtcgtgt cagtcgtgat
    12001 ggtgaaccac cgattcgtag cttttttgca aaattattct acaaattgat gaataaaatc
    12061 agccaggtcg aggtagtaga cggtgcccgt gatttccgtc tcatgcgtcg tcacatggta
    12121 gatgccattc tatctgtgtc tgaatacaat cgcttttcaa aaggaatttt tgcttgggta
    12181 ggattcgaaa cagaatactt gccctatgaa aatgttgaga gggtcgctgg cgaaactagt
    12241 tggtctttct ggaaattgct ttcttattct attgaaggaa tcatcaattt ttcagataca
    12301 cctttgaata ttgcctccta tacaggtttt ttcaccttcc tattgtcgct agttctaatg
    12361 gtttttgtgg ttttcaaaac cttggtgttc ggagatccta caattggctg gccgtcgact
    12421 atttgtatca tcctattttt gggaggtctg cagttgatga ccattggtat tctcggtaaa
    12481 tatttggcaa aagttttctt ggaaacgaag aaacgtccga tttatattgt taaagagaaa
    12541 agttcaaact aggagcagtt tatggaacat tcagcttggc acgaattgat aaaggcacag
    12601 ttgccagagc attattttgg taaaattaat cagtttttag atcatgttta tgctggtgga
    12661 accatttatc cgcctcgtga gaaggtattt gctgccattc aaacaacgga tttggaagag
    12721 gttaaagtag ttattttggg acaggatccc tatcacggac ctggtcaggc acagggcttg
    12781 tcattttctg ttccgaactc ggtaccagct ccgccatctc ttcaaaacat tttaaaagaa
    12841 ttgacggatg atattggcgt caaacaagat catgatttga cagcatgggc ggaacaaggt
    12901 gtgcttttgc tcaatgcttg tttaactgtt ccagcaggtc aggcaaatgg acatgcaggg
    12961 caaatctggg agccttttac ggacgctgtt attaaggtgg tcaatagctt agaccagcct
    13021 gttgtctata ttctttgggg tgcttatgct cgcaagaaaa aggcgttgat aaccaatcca
    13081 aaacatctgg ttatcgaatc tgctcatcca agccctcttt cagcctatcg aggtttcttc
    13141 ggaagcaagc ccttctcaca agcaaatgcc tacttgactt cacaaggcag aacaggaatt
    13201 gattggctgc gatagtagat ggtaatggct ttggtactac aaaggagaat atgaatgtta
    13261 ttagtgaaaa atggtcgagt attggatccg caatccggtt tagacaaggt ttgcgacatc
    13321 ttgatggacg gaagtaagat tgttaagatt gcggagtcga tttcagaaga tgttgagcaa
    13381 gaagtgattg atgcgacagg attagtcgtt gctcctggtt tggttgatgt tcatgtgcat
    13441 tttcgggagc caggtcagac ccataaagaa gatattcata caggagctct ttctgcagca
    13501 gcgggtggtt ttacttctgt tgtcatgatg gctaacacta gtccgacgat ttcaaatatt
    13561 gaaaccttaa aagaagtatt ggattctgct aaaaaagaag ccatccatat ttatagtgtg
    13621 gcaaccatta cagatcattt cgatgggcaa aatctgaccg attttcctgc tttgctagaa
    13681 gctggagcgg tggccttttc ggacgatggt attcctttga caaatgctgg cgtggttaga
    13741 aaagctatga aattagccaa agagcagggc tgtctcatca gtctgcatga agaagaccct
    13801 gacctgaatg gtgtcttggg actcaacgag caagtagctg aaaaacattt tcatgtttgt
    13861 ggagcaacag gcgtagcaga atacagtatg gtcgctcgcg atgtcatgat tgcctatgaa
    13921 acgggtgcgc gtgttcatat ccagcatcta tccaaagccg agtcggtcaa ggtggttgaa
    13981 tttgttcaag gtctcggagc aaacgtcacg gcagaagtag caccccaaca tttttcacga
    14041 acagaagaat tacttctaac aaaaggtgcc aatgctaaaa tgaatccgcc actacgatta
    14101 gaaagtgatc gcttggctgt gattgatggg ttgaaatctg gtgttatctc tgtcattgcg
    14161 acggaccatg cacctcatca cccagatgag aaaaatgtag aggaccttac gcaagctcct
    14221 tcaggaatga caggcttgga aacttcgctt tcacttggtt tgacgcatct ggtggaagaa
    14281 gggcatctga cactcgtaca attgttggag aaaatgacca ttaatccagc caagctctat
    14341 ggtcttgatg ctggctatct tgctgaaaat ggcccagccg atcttgttat ttttgaccca
    14401 aatgcaaatc ggttggtcac agcggatttt gcctcgaagt ctgcaaattc tccgtttgtt
    14461 ggtgatagtc tgaaaggaca ggtcctttac accattgcaa atggacaaat agtatttggt
    14521 aaataggaaa tgagcggatt agatagctaa ttcgcttatt tcgaaccttt ttaacatgta
    14581 agcgatttta atgtttttgt tttttgataa aaagtgtata atagagatat aaaaaatgcc
    14641 gaagaaaggt ctatttatga aaaagaaaaa aatcttgttg cctgtaatgt ccacactctt
    14701 gttggcgcca tttgttttag ctcaacaagt acaagctgct gagacaacga ctgcagctac
    14761 cacaaccaat cagccagcaa cgactgatgc aactgctacg gtaccagcaa cgactgatgc
    14821 aactgctacg gtaccagcaa cgtcagttga aaacgtagca acggaggaaa ctgttgtccc
    14881 tgctgcggaa gaaacagtag aggcagtcat tatccacaca aacgacgttc acggtcgcat
    14941 tcttgaagaa aagaatgtca tcggtgacgc taaggctgcg gcagtcattg aagaagaacg
    15001 tgccaaagta gaaaatacaa ttgtagtaga tgctggtgat gccttccaag gacttccaat
    15061 ttccaactct acaaaaggtg aagaccgcgc caatatcatg aaccaagtcg gctatgatgc
    15121 aatggctgtt ggtaaccatg aatttgactt tgggatggat caagcaatca agtacaagga
    15181 aaccttgaac ttcccgctat tgagtgctaa cacttacgtt aatggtgctc gtgtttttga
    15241 agcttcaact attgtcgata aaactccaac tgttgtaggc gatgaatttg tagttatcgg
    15301 tgtaacaaca cctgaaactg ctacaaaaac ccatccgaaa aatgttgagg gagtaacatt
    15361 taccgaccca gtcacagaag tcaataaagt gattgacgaa gtggaagcgc gcgctctagc
    15421 agataatcgt gtttacaaga actatatcat tctagctcac ctaggtgtcg attctacaac
    15481 gcctgttgaa tggagaggtt caactcttgc tgaagcactt tctaaaaata gtaaattagc
    15541 tggtaaacgt gttattgtta tcgacggtca ttcccacacg gtagaagcga ctacctatgg
    15601 agataacgtt acttataatc aaacaggctc ttacttgaac aatatcggta aagtaacctt
    15661 gaaatccgat aaattattgg gtgaagctag cttgatttct gctgcggata ctaaaaatgt
    15721 gacgccaaat gctaaaatcg cagccttggt tgatgaaatt aaagcaaaat atgaagctga
    15781 aaatgctcaa gtagttattg aaaataaccc agtggaatta aacggagacc gctcaaacgt
    15841 gcgtgttcgc gaaaccaact tggggaatgc agtgacggat gcgatctatg cttatggtca
    15901 aacaggattt tcaaacaaaa ctagccttgc tgtgactaac ggtggtggtc tacgtgcaac
    15961 aattgctaaa gatcagcctg ttacaaaagg tgatattatt gcagtcttgc catttggtaa
    16021 cattgtttct caaatcactg tgactggtca gcaaatttat gatatgttta ccaagtcttt
    16081 atcatctaca ttgcaagtga atccagaaac tggcgagatg cttttagatg aaaatggcat
    16141 gccgctcttt gaagctagtg gtggattcct acacatttca ggagcaaatg tattctacga
    16201 tccaactctt cctgtagaag aacgtgttct tcttatcggt attcttaatc cagagactgg
    16261 cgaatatgac gccttggatc ttgaaaaaac gtactattta gcaacaaatg acttccttgc
    16321 tgctggtggt gatggctaca caatgcttgg cggagcacgt gaagaaggtc cttcaatgga
    16381 cagcgtcttt gctgaatacc taaagacagc tgacttatca gcttatgagg ttgtcaaccc
    16441 atattcacgt atcattcctg taaattcaag cattgatacg gatgaagatg gctacccaga
    16501 ctttatcgaa attttattgg atactgatcc agaaaatcca gcctcaaatc cagaaactgt
    16561 tccagccgaa aatacggatt caccatctaa tcaagtacaa aatacttcag caacggacaa
    16621 gaaggcccca gttgattctc cgaaagtagg agataaaaaa acagaagtag caagtccagc
    16681 aaaaactaca aaagcaggag tcttgccaaa tactggtgat cagatgaatc tgacgctcag
    16741 cctgtttggt ttaggtcttg caggactggc cgtggcagta ggtcgtagaa aagaaaatta
    16801 atcaatcatc tgaaaacagg gtcttcggac tctgtttttg actggaggaa acatgcaaac
    16861 tgtatttcaa tatcaaaaag agggggattg tgagcagatt agttcttacg ttctgcttag
    16921 caactcccca cgtcgtaaac aattattggg atttttacaa ccacaaatcg catcagttga
    16981 agtggatgag cgtggtatcg aagaacattt tatgaaacaa ttcgctacag atgattttct
    17041 cactcgagct gcaaaaacct gttgtgaaat ttccaaagcc aaatcggaca tggatttggt
    17101 aactggtcat ctctacattt ctgcggatac aatcgtagtg tcagatgggc aaatttttaa
    17161 caagcctcaa gatttgacag aagctgaaac catgttacgt tcctattttg gaaagagtca
    17221 tcacgttgtt acatctgtct gcctacggac aagacactca ctggatgttt tttatacggt
    17281 tgcacagatt gattttgtcg actattatcc agcccttgaa gaggttattc aatcatatat
    17341 ccgtgaaaag cagccactcg acaaggcagg tgcctatggt attcaggagc tggatccacg
    17401 ctttgtagca ggtatttctg gggatattca caccattatt ggtctacctg tagcagaagt
    17461 ttcctgcagg attttttctg aagaaggttt tgaaaattag cagagcttaa ccattcgttt
    17521 gtggtataat agtggacgaa aaggagagat tatgaccgtc gacattgaaa gatacaagca
    17581 attggcccag cagaagcaag gagaacatcg aaaatttcta gcaaatttga agaagaaaac
    17641 acctaaaaat ttggatagaa ttgttcaaga tattcatgcc gaagtatttt ctgaaatcga
    17701 ctgtacagag tgtgccaact gttgtaaaac attgggacca ctctttacag aagcagatat
    17761 tacccgaatt gccaagcatt tgcgcatgaa acttccagtt tttgaggata tgtatttgcg
    17821 tatggatgag gacggagata aggtatttca atccatgccc tgtcccttcc ttggaggcga
    17881 taatctatgt agtatctatg atgctcgtcc caaagcctgt cgagaatttc cacatactga
    17941 ccgcaagaag atttatcaaa tcaacaattt aacaataaaa aatactctga tttgtcccgc
    18001 agcctatctc tttgtcgaaa agttacggga gagaatttaa gaggaacaag taagacaaaa
    18061 tattgatttt ctgctataat aataaaaaaa caagccgttt ttacggcttt tttcaatgaa
    18121 tcatatttag gaggacccca tggcaattat tcaatggttt ccgggccaca tgtcaaaagc
    18181 tcgcaggcag gtgcaggaga acatcaagca cgttgatttc gtgaccattt tggtcgatgc
    18241 ccgtctgccc ctatccagcc aaaaccccat gttgaccaag attgtcggag acaagcccaa
    18301 gctcatgatt ctcaacaagg tcgacttagc agaccctgtt cgtaccaaag aatggcagag
    18361 ctactttgaa ggtcaaggca tccgtaccct tgccatcaac tcaaaagagc aagcgacggt
    18421 gaaaaaggtg accgacgcag ccaagggtct gatgaaagac aagattgaac gcctccgcga
    18481 gagaggtatt caaaaagaaa ccttgcggac catgatcatc ggtattccaa acgctggaaa
    18541 atccaccctc atgaaccgtc tggctggtaa gaaaatcgcc gttgttggca acaaaccagg
    18601 tgtgacgaag ggccaacagt ggctcaaatc caacaaggac cttgaaatcc ttgatacacc
    18661 tgggatactc tggcctaaat ttgaggacca ggaagttgga cttaagttgg ctctgacagg
    18721 agccattaag gatcagctct tgcctatgga tgaagtgact atttttggtt tggactactt
    18781 caaagccaac tacccagaac gtctacaaga gcgatttaag gggatggatt tggagcagga
    18841 aacacctgaa ctcatcatgg actggaccaa gaaattgggc tttcgtgatg attatgaccg
    18901 tttttacaac ctctttgtca aggacgttcg ggacggtcgc ttgggtactt atacattaga
    18961 cagggtgagt gacttagatg gcaacgatta aggaagtgac agctctgctg gcccaggtag
    19021 acagtctgga cagtccagtc tgggaccaac tggctcagga tgagcgagca ggggtccagg
    19081 ctgctatcaa gaaacgccgt aaggagctgg aaaaagaagc ggtagaagat gcccgcttag
    19141 aagctatgct attctacgaa aaatcccttt atgaaaatgg ggtggagttc atcgctggta
    19201 tcgacgaagt cggccgggga cctctagcag gtcctgtggt ggcagcggcg gttatcttgc
    19261 ctaaagggtg caaaatccgc tacctcaacg actccaagaa aatccccaag tccaagcatg
    19321 aagcaatcta ccaagaggtt atggagcgag cggtggcagt cggtgtggga ataaaagatg
    19381 cagctctcat cgacgaggtc aacatctatg aggcaaccaa gttagccatg ctggaggctt
    19441 tggggaaatt aagccagaaa cctgaccact tgctcataga cgccatgaag ttggatacgc
    19501 ccataccaca aacttccatc atcaagggag atgccaatag cctatctatc gcagcggcct
    19561 ctattgtagc caaggtgacg cgggataaga tgatggcgga ctatgacaag gagttctcag
    19621 gctacggctt cgccaagaat gctggctatg gaacgacaga gcacttggaa ggcttgaaca
    19681 agttaggcat cacgcccatt caccgtaaga cctttgagcc cattaagtct atggtagcag
    19741 ggggaaacta gtcttgacag tctttttctg gttattttta gcggctatcg gtctgtttgc
    19801 tcttgtctat ttctgggagc ggcggtcgat ttttatctca ctgtttgctt tgaacatcct
    19861 cgtctgggct ttagcatgga ttatctcaac aggcattctc gaatacaatg aaatcttgcg
    19921 cttgctggct atagcagtgg ctatggtgct ctttttagcc ttgttaagtg gtccatttgt
    19981 cttgcttttc acactttatc taaatggttt tcaaattttg aagagagaag gggttcgctt
    20041 ccataatttc ctatccatgg gactggcggt agccttgact ttctatctct tcatcgctcc
    20101 ctttgtggtt caatctctat cagccatcag ctttttcaat atggtgtttg tgtacgttgg
    20161 tttttttgtg tcctatgcca ttatcatcag catgctctat accatgtcta gctttgtcaa
    20221 tttggtcaat tttttcccag gcaagcttga ttatgtagtg gtcttgggag caggtctgat
    20281 tggtgacaag gtaacgccac ttttggcttc gcggattgaa aaaggcatag cgatctacca
    20341 gaaacagcct ggcagcaagc tcatcatgtc aggcggacaa ggtcctgatg aactcatagc
    20401 agaaggacag gcaatggcaa attatgcctt ggagaaagga gtgcctgctg aagacattct
    20461 catcgaaaac caatcaacca acacagaaga aaatttgaaa ttttcctatg ccctgatgaa
    20521 acctggcagt cgatttgcac ttgtaaccaa ttactatcac gttttcagag ctctgctatt
    20581 ggcacgacaa ttgagaatca aatgtatcgg ctacggcgca aaaaccaaat tttactttag
    20641 ccttaatgcc ttcattcggg aatttgtagg ctatgtagtc atgagccgaa aggcgcattt
    20701 ggtctttttg agcatcgtgt cagcccttta cttgattgga gtgatcatca gtttaatgca
    20761 ttaaaaacag cctctaggtg actagaagct gttttcttat aacataaagt agacaatggc
    20821 gatatactga agtgccgaag ccagtaggat aaagagatgc caaatcatgt ggaagtaggg
    20881 ctttttcttg gcatagaaga gggctccaat agtataagat aatccaccag ccagcatgag
    20941 aatgccaaat gccattccag tcttttgcag aatggctggc aggataaaga ccaccaacca
    21001 gcccataaag agatagagga aaaggctgaa tttttcattg atttttttgg caaatatttt
    21061 gtagagaata ccaaaaatag ttaatcccca ttgtaaacct acaatcagat aacctagcca
    21121 accaccgacc aaggaaaggg caacaggtgt gtagcttcca gcgatggcaa tgtaaatcat
    21181 gctatggtca ataatcctca ggatgtattt gtgagtagaa gcatagggca tggagtggta
    21241 gatggaagag gataggaaca tgagaaatag gctgatgaca aagatggaca taccaatcac
    21301 agcggtcagg ttataatctt gataggaatg aatagcagta acggggagca agaccaacat
    21361 aagcagggct ccgactgcat gtgtgacact gttagcaacc tcctctccaa aggatagttg
    21421 caggctcaat ttcaaactag gattcatggt gactcctttc taactccata gtgagttgac
    21481 gggttttgta gtaaagtttg acagattgac aagcgtagcg aatgatgtca ggggtttctt
    21541 cattttcctc gtttcgcatg cagtcaacaa aatgattgta gagtgtttct gaatgactcg
    21601 attggagaag aagatttaag gtctgactga tttcttgaat cgaaaagaca ttttttaaga
    21661 tagtcaaggc aatcaagcgg gcaacttgct gtttctggta ttttttcttt accggttttt
    21721 caagttgctt gtgcttgaca taattgttaa tcatagcagc agtcaatact cttcgaaaat
    21781 caacattatc cgttatcaac ttgccttgat gaaccccagt tctatcatca gcttcgtttc
    21841 ctaggctact gttgattttc attgagtata aactcttctg ttcaaggctt tcctgagaat
    21901 tgactacttg attaacatac agcagaactt ggtccaaata caaatctaaa tcaggtaatt
    21961 catgccagta gggaatggtc tgtttcatga ttatctactc tcttttatct agtaatgata
    22021 actagattgt acgatataca atatttaatg tcaagaaaaa accttctgga cccaaaatca
    22081 cagaaggtta gttgcttatg gttggataat atttttaggc aatgtcatct tataaagtga
    22141 ataggctcca tctaggtttt taactataaa accattttct tttaagatac gttcggcaat
    22201 ataagaacgc agtccactat ggcagctgac aatgtattct tttgaagcat ccagttctcc
    22261 aattcgctca cggagttggt ccaaaggaat gtgaatgaat tctctgaatt gcccatttgc
    22321 gacctcacca ggattgcgga catctaatag aactttacca gtagctaact cgtcgtctag
    22381 ttgataccac tggatgtttt ggctaatccc ttctgcgatg ttcatagcag cgtagccaat
    22441 catattgaca gggtctttgg cagagccaaa tggcggagcg taagtcaatt ctagctctgg
    22501 taaatcaaaa attgtcagtc cagccttgat agcagtggca aggacatcaa tccgcttatc
    22561 aatacctttt tgaccgacgg cttgcgctcc gaaaattttt ccatcagtcg gtgagaaaat
    22621 gagttttaaa acaatatcag tcgcaccagg ataataacct gcatggtctt ttccagttgt
    22681 atgaacgacg gcatgtttat agccgagtga ttgaacagca cgttcgctta aaccagttga
    22741 agcggcagct agagctaggt caaagacttt tacgatagct gttccaatag atcctttgtt
    22801 ttttctatca agtccagcaa tgacatcagc tacctgtctt ccctgacggt tagcaggaga
    22861 agccagtgaa atcaaggcat cttgacctgt aatttcttgt ttaacaacaa tagcatcacc
    22921 aacagcataa atattcttct gactagtttg gtagttttgg tctacgagaa taccaccacg
    22981 gagacctaac tcaactccag catctttggc tagttgactg tcgggagcaa ctccgactga
    23041 gagaatggtc acatcagatg acaaggtttg tccgttagac aattctagaa cctgtccttt
    23101 ttcatgaaaa gcagtaacag actgcccagt gataacctcg acacctttat tggttagctc
    23161 tgcttccaca tatcgtgcca tttctaagtc aaaagtaggt aaaacatggg gagcttgttc
    23221 gacaagcatg accttccagc cttttaaagc taagttttcc gccatttcca gaccgataaa
    23281 acctgcacca attaccacaa catgaccaga cttgatctgg tctagtttaa tcataatctt
    23341 gtccaaatca ggtacgttcc gaagagtaaa gagattgttt gcttcttcaa taccagatag
    23401 atttggaatg acaggcttgg cgccgggtga taagattagt ttgtcgtagc tttcaatcaa
    23461 ctcaccagta ggcgttttga ctgttacagt ttgctgctca gcatcgatac taatgacttc
    23521 atggaagggg cggacatcta gattaaagcg ttgtttcaaa ctttctggcg tttgaagcaa
    23581 taaactgtca tgctctgcta tttctccaga aatgtaataa ggtaaaccgc agttggcaaa
    23641 ggaaacataa ggtcctttct caaaaacgat gatttcagca ttttccatca aacgacggag
    23701 acgagtagct gctgacatac cgccagcgac accacctaca ataattattt tcatgctatt
    23761 cctcctgtcc aggcattcat accgccttta acgttgattg cttgatagcc ttgagattta
    23821 agatattctg tcgcccgttg gctacgcatg ccagattgac agatgacaag atagttcttg
    23881 gttttgtcgc ctttaaattg gtcaagttga cttaagggct ggttgatagc ttgtggaata
    23941 tgtccactag caaattcgtc gacttcgcga acatcaagca aaatagcatt cgatgattgt
    24001 atcgcttgtt ctacatcagt tatcggaaga ctatctgagt ttgaaaacat tcctgaaaat
    24061 aattgtttaa acattgttac tcctttatac cctacagggt atctaaaata tatcaaggaa
    24121 ttcgaaagat gtcaaggtaa aaaattgaca tttttcactt caagcagtac catatagggt
    24181 atgaatactg ataagaaaaa gatgataaac cgtttgaaac gggccgaagg tcagctcaga
    24241 ggcattcaga aaatgattga agaagatcag gaatgtattg atattgtaac tcagttgagt
    24301 gctgttcgtt ccagcattaa tagtatgatg ggaatggtta ttgctcagaa ggtacaagat
    24361 tgtatcactc atccatctga aaaccctgaa gaacaagaag ctcgtcttgc tcaagctatc
    24421 aatttaatca taaaaaaata ggagtagggg tatgtcgaca gaaaaagaaa agatgatagc
    24481 tgggcaattt tatatggcag cagatgctga attgagaaag atgcgaacct ttgcccgcca
    24541 acagatgaaa aaatttaacg aagaactaga tggaaaagcc cgctctgagc gattgaaaag
    24601 ctggtttgga actacaggcc aacgcatcta tatggagccc aatttctact gtgactacga
    24661 tagcaatatt catgttggtg aggattttta cgctaatttc aactgtacca tgttggatgt
    24721 ctgtcccatt accattggca aaaatgccat gcttggtccc aatgtacagt tgctaactcc
    24781 acttcatcca ctagatcctg atgaacgaaa ttctggtttg gaatatggct ctcctattac
    24841 cattggtgat aatttctggg ctggtggtgg tgtgacaatc ttacctggcg tgaccttggg
    24901 caacaatgtt gttggtggtg ctggttccgt tgtgaccaag tcttttggtg ataatgtcgt
    24961 tttggctggc aatcctgcgc gtgttatcaa agaaatacct aaaaaataat tcttcttcgg
    25021 gagaattttt tctttgcctt gcgaatagac tagatgaggt gaagaaaatg aataattttg
    25081 aattgtttaa atggaaaaaa gcaggtttga ccaatcttaa tgtgaataaa gttttggcct
    25141 atcaagaaaa acacggtaaa aaattgacct tgcgaaatgt cgctgtagtg tctgaatgta
    25201 aaaatccagt gctatttatg gaaaattata agaatctaga tacaaaagcc tgtcgcgagg
    25261 aatttaataa gtatccatca ttttcaattt tagatgacat ctatcctttg gcgctcaaac
    25321 agatttacaa tccacctgta cttttgtttt atcaagggga tttagaattg ctagaaaaat
    25381 taaagctggc agttgttggt acacgaaatg ccagtaaaaa tggtatccaa tctgttcaga
    25441 aaattatcaa ggaattgagc aatcgttttg tcattgttag tggtttggca agaggaattg
    25501 atacagctgc ccacatcgcc agtttgaaaa atggaggcca aaccattgct gtaatcggaa
    25561 caggtttaga taatatttat ccaaaagaaa ataaagattt gcagacctat attggaaaac
    25621 accatttggt gctgacagag tatgaagctg gtgctcagcc actcaaatac cattttccag
    25681 aacgcaatcg cattatagct ggtttggtgg aaggattggt agtctgcgag gcaaaaatgc
    25741 ggtctggcag cttgattact tgtgaacgtg ccttggaaga aggaagagaa gtctatgcta
    25801 ttccaggttc cattatggac ggaaaatcag atggttgtca tcatttgatt caagagggag
    25861 caaagtgcgt tacatcagga ttggacatca tttctgagta tcaattttaa aacaagtctt
    25921 cctataggaa aataaatatc ttgacactga ctgaaaaata gtatattctt tgtgaggtta
    25981 aaaatatttg taaggtataa gaatggctac aaaaacagtt agtaagaaaa aaacaacaac
    26041 caagaaaaat ctcgttattg tagagtcacc tgctaaggca aaaacaatcg aaaaatatct
    26101 tggtaaaaat tataaggtcg ttgcttcagt cgggcatatt cgagatttga agaaatctag
    26161 tatgtctatt gactttgata acaactatgc acctgagtac atcaacatac gtggaaaagg
    26221 accactcatc aattctttga aaaaagaagc aaaaaatgct aagcaagtct ttctcgcgag
    26281 tgacccggac cgcgaaggag aagcaatttc ttggcatttg gctcacattt tgggattgga
    26341 cgcaaacgat aaaaaccgtg ttgtctttaa tgaaattaca aaagatgcag taaaaaatgc
    26401 ttttcaggag ccgcgcgcta tcaatcatga cttggtagat gcccagcaag ctcgtcgcgt
    26461 cttagaccgt attgtagggt actccatatc acctatttta tggaagaaag tcaaaaaagg
    26521 tctgtcagca ggacgtgttc aatcggttgc tctcaaatta ataatcgacc gtgaaaatga
    26581 aatcagcaat ttcaaaccag aagaatattg gacaattgat gcaaccttca aaaaggggag
    26641 caagaaattc caggcttctt tctacggtat agatggaaag aaaactaaaa ttgaaaacaa
    26701 tgagcaggtt aaagaaattc tcgcccgact tgatggggat gatttcttag tagaacaggt
    26761 tgagcgtaag gaacgcaaac gaaatgcacc tctgccttac acaacttcta ctatgcagat
    26821 ggatgcggct aaaaaaatca atttccgtac tcgtaaaacc atgatggttg cccaacaact
    26881 ttatgagggt gtcagtcttg gcacaggtgg tacccaaggt ttgattacct atatgcgtac
    26941 ggattcaaca cgtattagcc ctgttgcaca agcacaagct gctgacttta tcacggagcg
    27001 ttttggtgct acctattcaa agcatggtaa taaagtaaaa aatgccagtg gtgcacaaga
    27061 tgcccacgaa gccattcgtc catcaaatgt taacttaaca cctgaatcaa ttgcaaaata
    27121 tctggacaag gaccagttgc gactatatac actgatttgg aatcgttttg tcgcaagtca
    27181 gatggctgca gcggtctttg ataccatgag tgttcgtcta ggtcaaaatg gagtgatttt
    27241 tgctgccaat ggtagccaag ttaaatttga tggttacatg gcagtctata atgattctga
    27301 caagaataag atgttgccag atatggagca aggtgataca gttgtacgta catcaacaaa
    27361 tcctgaacaa cattttacgc agccaccagc tcgctattct gaagctactt tgattaagac
    27421 tttggaagaa aatggtgttg gtcgtccgtc aacctatgca ccaaccattg aaaccattca
    27481 gaaacgctac tatgttaagt tagctgctaa gcgatttgaa ccgactgaac tcggcgaaat
    27541 cgttaataag ctgattgttg aattcttccc agatattgtc aatgtcaaat ttacagccga
    27601 tatggaacaa aaattggatg atgtagaaat cgggaaagag cagtggcaga aggtcattga
    27661 tggtttctat cagccattca aggtagaatt atttaaggca gaagaacaga tggaaaaaat
    27721 ccaaattaag gatgaaccag ctggctttga ctgtgatgtt tgtggacatg aaatggtcat
    27781 taaactaggt cgttttggaa aattctatgc ttgtagtaat ttccccgatt gccgcaatac
    27841 caagcaaatt accaaggaga tcggcgtaac ttgccccgtg tgtcaacaag gccaggtcat
    27901 tgaacgaaag agcaaacgca atcgactttt ctatggttgt gaccgttatc cagagtgtga
    27961 atttacctca tgggataaac ctgttggtcg tgcctgtcca aaatgtgacc actatcttgt
    28021 cgagaaaaaa gttcgtggtg gtggtaaaca agttgtctgt ccaaatggtg actacgaaga
    28081 agacaagatt aaataagatt aaactgctat tctcaaggga atggcagttg ttttttatag
    28141 tcatgttagt ttatcttagc ttacttcgac aagcgaggaa acttcgtttc cttattttca
    28201 actttaaatg aggctggtca aaaagtccaa agtcacttct cagtgcagtg gttgattggg
    28261 tttaacaggc cagtggagtg aaactgttca gtgaactgtt tcagcctgag cttagaaatg
    28321 aaaaaatcga ggtaaaaagg ttggagataa gatttgcgaa gcaaatcaca gcaattcgtg
    28381 tttcacattc caagtctgac ctctacaact aaaacgaact aaacggcaat accagtttga
    28441 aaaattgttt aaaaaattaa aaaaatagga gaaaagtctt gcattattga aaatactgtg
    28501 ttatgataat tgaggtttga aaaaactgac ctaagacagt aggggagctg gactcataaa
    28561 catcctaccg aggcacaaaa cgattattga gataaacgta tttgtacttt cgtgtctagg
    28621 tttaggtgcg atttttttgt gcctagccca aaataaaaac ggaggtaaaa aaatgagtga
    28681 agctattatc gctaaaaaag cggaattagt aaatgccgtt gctgagcaaa tgaaagctgc
    28741 aacatctatc gttgttgtag acgctcgtgg tttgacagta gaacaagata cagttcttcg
    28801 tcgtaacttg cgtggtgcag aagttgagta caaagttatc aaaaactcaa tcttgcgtcg
    28861 tgctgctgag caagctggtc ttgaaggtct tgcagaattg tttgtaggtc catctgcagt
    28921 tgcattctca aacgatgcag ttgctccagc taaaacaatt tacgatttcg cgaaaactgc
    28981 tgatgctctt gaaatcaaag gtggtgctgt agaaggtaaa gtttcttcta aagaagaaat
    29041 cgaagcactt gctacattgc caaaccgaga aggcatgctt tctatgttgc tttctgtact
    29101 tcaagcgcca gttcgcaacg ttgcatacgc tgtcaaagct gttgcagaaa aagaagacgc
    29161 tgcttaatgc gtcagagcgt agctgcttag tgctacaaac tatttaaaaa cctaaattgg
    29221 aggaaaatca caatggcatt gaacattgaa aacattattg ctgaaattaa agaagctact
    29281 atccttgagc ttaacgacct tgttaaagct atcgaagaag aatttggtgt aactgcggct
    29341 gctcctgtag ctgttgctgc agctggtggt gctgctgaag aagctaaaga ttcattcgac
    29401 gttgaattga catctgctgg cgacaaaaaa gttggcgtta tcaaagttgt acgtgaaatc
    29461 actggtcttg gtcttaaaga agctaaagag cttgttgacg gtgcaccagc tatggttaaa
    29521 gaaggcgttg caactgcaga agctgaagaa atcaaagcta aattggaaga agcaggcgct
    29581 tcagttactc ttaaataata gagtttccaa tcaaaataaa aacctatcac ttaatgtggt
    29641 aggttttttc gttctattgt tgcaaacgtt ttcgttgtgg ggtataatat aaaaaatgat
    29701 gtctaaagat taggagaaag acatgaaaag ttacaaaaac tatatcttcg atttttatgg
    29761 tacattggtt gatattcgta cagatgagaa taaactagag gtctggaatc agctaacaca
    29821 gatttacaat gcttttggtt gttcctatcg accgcgccag ttgaaaaatg cctatcatcg
    29881 ttttgtagaa gaggcagaga gctctctcgc ggaaacagtg agttatcagt atgtcgaaat
    29941 tgatttagaa acaatcttca ttcgtctatt aacggatgca ccaaatgaaa accaaagtac
    30001 caataagccg actgatttag agacttttgg acaagtagta gccacgattt tccgcgtgct
    30061 ttcacgtgaa aagttagagg cttatgaaaa taccctaact agtctacaga cattaaagga
    30121 cagagaagtg cgattattta ttctctccaa tgctcaacga atttttactc aggcagaaat
    30181 tgaacagaca ggttgtgctg atttgatgga aaaaatttat atctcttctg actttaagat
    30241 gaagaagcct gaaccagcat ttcttcaact ggttttagag gaaaataatc ttgatgttga
    30301 ggaaacggtt atggttggta atgatttgac atccgatata gctattgctc atgaattggg
    30361 aatggattcc attttgctga atactttccc gtatagtcag gaagaaatcg actcttatag
    30421 gagacttggt tggaattttg aggttgttgg agatatagcg gagctattgt aaataagcga
    30481 tagaacagta aaggatatac ataaaatata ttatgtaaaa aggtgaaact actttcattt
    30541 caatgaaggt agttttgtcc tttctagcca ttttctggta tactagatag gtataaaatt
    30601 tagaaaggtt ctgtttttgg gtattcccaa acagtagtca gatattctgg ctagaggtat
    30661 tagtttcatg tctcaaaccc acattaatgt tataggagct ggcttggctg gctcagaagc
    30721 tgcttatcag attgccaaac gtggcattcc tgtcaaactc tacgagatgc gtggtgtcaa
    30781 gccgactcct cagcacaaga cggacaagtt tgcggagttg gtttgttcca attcattccg
    30841 tggtgatagt ttgaccaacg ctgtcggcct tcttaaggaa gagatgcgtc gtttggattc
    30901 cattatcatg cgtgctggag aggctcaccg tgttcctgct ggaggtgcca tggccatgga
    30961 tcgtgagaat ttctctcaag cggttactga tgagattcac aatcacccgc tgattgaggt
    31021 catccgtggt gagattaccg aaattcctga agatgctatt acagtcattg cgacggggcc
    31081 tttgacgtct gacgccttgg cggagaagat tcacgcgctt aatggtggtg acggttttta
    31141 cttctacgat gcggcagcac cgattgtcga cagctcgacc attaacatgg acttggttta
    31201 tcttaagtct cgttacgaca agggagaggc tgcctatctc aatgccccta tgaacaagga
    31261 gcagttcaac gctttctatg aggccttgat ttcagccgag gaagcaccgc ttaactcctt
    31321 tgaaaaagaa aaatactttg aaggctgtat gcccattgaa gtcatggcca aacgtggtat
    31381 caaaaccatg ctctatggcc caatgaagcc agttggtctg gaatatccag aagattacaa
    31441 gggaccacgt gatggcgaat acaagacacc ttacgcagtt gtccagctcc gtcaggataa
    31501 cgcagcaggt agcctttaca atattgttgg cttccagact caccttaagt ggggcgagca
    31561 gaagcggatc ttccagatga ttccaggact cgaaaatgct gagtttgtcc gctacggcgt
    31621 tatgcaccgc aattcctaca tggattcgcc aaacttattg gaacagacct ttgcgaccaa
    31681 gaaaaatcca aatttgttct ttgcaggtca aatgacagga gtagaaggct atgtcgagtc
    31741 tgccgcctct ggcttagtag ccggtatcaa tgctgttcgc cgtttccatg gcgaagagcc
    31801 agtcatcttc ccacagacca cagccatcgg agctctgcca ttttacatca cccacaccga
    31861 aagcaagcac ttccagccta tgaatgtcaa ctttggtatc atcaaggagc tggacggacc
    31921 gcgtatccgc gataagaagg agcgttatga ggcaatagca gagcgttccc tcaaggactt
    31981 ggaagagttt ttgacggttt aagccgatag ttttccgacg aaaagtatcg ggaaaacttg
    32041 gatggtagat ggtaaactga tagggaaagg ggaagttgat gataaaagag ttcaatgcaa
    32101 ccgtacgtta cctagagtcc gttttagaaa gcgaaatcga tgaacgggaa tttttgcgca
    32161 tatcaggata ttccgttccc atgtttagtc gtctcttttc gattctgaca gatatgtcct
    32221 tgtcagaata cgttcggtta cgaaagttga cgcgagctgc tatggacatt cgtgaaggac
    32281 aggcaaagat tatagatata gcccttaaat atgggtatga atcttcggat tcttttgcct
    32341 ttgccttcaa acaatttcat cagatttctc ctagtcaagt gcgtaagggg ttgcctttta
    32401 aggtcctctt acccttgcaa ctatcattaa ccatccaagg aggtaaagaa atggatgttc
    32461 gtattgaaaa gaaggctggt tttacagttg ctggacttct tcgcacagca atcagtaacg
    32521 aagtgtgtcc gcaggtatgg gaagacttgt tcaagaacca tacttatgaa gagttagctg
    32581 ctctaggaag tgggcagtcc tttggagttt gtacattagc tcaagcggac gagacgatta
    32641 attatatggc tgcttatgat gtcacagata gtgaaaaagc gactaagtta ggcttagaac
    32701 ttcttgatgt tcacgaagct gactatgcta tttttaccct aacaggccct gttcctcaat
    32761 ctattcatgc aggatggcgt tatgcgctag aaactttttt tcctgaacac ggctatcgcc
    32821 attcaggtgc accagatttt gagtactatt ttgaaggaga catgagttcc ccagactacc
    32881 aaatggaact ctggattccc attgtgaaag cataatgtac aggacacctt cgggtgtctt
    32941 ttgtgttata ctgggattag aaagcggagg agaaatacga tgcaccacaa tacttggaag
    33001 ggaattattc tgcagaaaca aggtctgttg aacccccagt ctgttcaaca aatctgccaa
    33061 aatctcaatg gtttgcaggc tcagtttcag ccctatgttc atgtcggatt tcgtaaccgt
    33121 atgacagcgg aggattttca tgagggtagc tggcaggagg aactgactcg tcagtggtcc
    33181 attcggcgaa cggttcatgc ctatctcgag tcggaaattc ctctctatat ccatgagggg
    33241 cggctggtca gcaccgatta cctcaagaca gaaggacggg acggttttag tcctcagacc
    33301 aagcagaaat atcaccatct gattttagaa gcccttgaac aaggtcctat gacccgtgag
    33361 gatctcaagg tcctttgccg agaggaaaag atgacacaga aagaggagaa gctggtcttt
    33421 aatgcctggg gcggtctctt tcgctacatg gtcgagcgtg gggaagtcta ccaagagtac
    33481 ggtgccaagc gttttcatcg tctgacagac tttcagccac tttctcggga aaaagctgag
    33541 ctggaaatag cacgtcggta tttttcaggc tttgggccag tcagtctagc agatgctcgt
    33601 tattatttca aagaaaataa gtcaaccatt ctagagtgga tggctcaatt agatttaaaa
    33661 acaattcaag tagctggaga ggagcggttt taccttgggg tgcttgatga ggcagattta
    33721 cctcagtgtc ttttcgttgc tgggtttgat caattacttt tgggctatga aaagaaaaac
    33781 aacccatttt tcgatccaaa atacatccgt aacatttata cgttgacggg tattgtcaaa
    33841 cctgttgtat tttataaagg gcgatttgtg gcaacctgga aacgtgataa aggtaccatt
    33901 ttgctagata tttttgaaag catcacccaa aaagaagaaa aagaattaga ttattaccgc
    33961 caaatgtatg agaaaattct gtgacattga ctaactatgt tcggaaaatc cgaaaattgc
    34021 aaataaataa ctaaattttc tgaatattcc agaaaaacta tgatataata cttaaaatac
    34081 gtaaggaaga gatagatatg aataagtctt acttttattt ggacatgaga actcatgaat
    34141 tagatgtacc atttacagaa agaaaacgtc gagtccgtgt tttattgccg aaaggatatg
    34201 ctgaaaatac agaagagacc tatcccgttg tttatttcca cgatgggcaa aatgtactct
    34261 acagtaagga agctttttca ggtcattcat ggaaagtcat cccaactatt aagcgtaatc
    34321 cagacattgc aaaaatgatc gtagtggcta ttgataacga tggtgctgat cgcatgcatg
    34381 aatacgctgc ttggaagttt agtgagatgg ggattcctgg ggtgcagttc ggtggtaagg
    34441 gaaccttgta tgctgaattt gtgatggatg tcgtcaaacc atttattgat caagaatacc
    34501 ggacaaaatc tgataaagtt cacactgcaa tgattggctc atccttggga ggcaatatca
    34561 cccagtttat gggattggct tatcagaacc agattggctg tctaggagta ttttcatctg
    34621 ccaactggct tcatcaagat gctttcgacc gttatattga acgtcaacaa ttagactcag
    34681 agcaacgagt ctacatctac gttgggacag aagaagcaga tgatacagat aaaacattga
    34741 tggcaggaaa tatcaagcag gcctatatca attcttcatt gacttactat cgtcaattga
    34801 tcgctggcgg agtggatttg gacaatatcg ccttggaagt cgtttcaggt gcggtccata
    34861 atgaagaggc ttgggcgctc tatttgccag cttgcctacg attcctaagc gaacattggt
    34921 cataaaacaa aaatatacaa ataggaggct ttactatgca cgttgaattt ttaagtcatt
    34981 ggtctggaaa tcttggccga gaaatgaatc taaatcgtta tggtcacgta gggattcctg
    35041 ttgtcgtatt tgcttcatca ggtggttctt acaatgaata tgctgatttt ggtatgattg
    35101 aagcttgtcg tggctctatt gaagctggtc aggtccaatt ttttactcta actagctacg
    35161 atagtgaaag ctggttggca gactggaaat ccatccatga caaggcagag gctcaccgtg
    35221 cctatgagcg ttatgtgatt gaagaagcga ttccctttat caaacataaa actggttggt
    35281 ttgatgggat gatgacaact ggttgttcta tgggagctta tcacgcgctc aatttcttcc
    35341 tgcaacatcc agatgttttc acgaaagtta tcgccctttc aggtgtctat gatgctcgtt
    35401 tcttcaacaa caatcaagat tatggcaatg atgatgttgt ttatcagaac tcaccatcag
    35461 attacatttg gaaccaaaac gacggctggt ttattgataa ataccgtcag gctgatatta
    35521 tcgtctgtac aggtttgggc gattgggagc aagacggttt ggactcattc tataacctca
    35581 aacgtgcatt tgaagagaag agtatcccag cttggtttga tacttgggga acagatgtgg
    35641 cccacgactg ggtgtggtgg agaaagcaaa tgccattctt ccttcattct atcggactat
    35701 aagctagaaa ggactaccta tgaattatct cgttatttca cctttttatc cagaaaattt
    35761 ccaaccattt accattgaat tggcaaaaaa agaaggcgtt acggttctag gtatcgggca
    35821 agaaccttac gatcaattgc ctgaagaact tcgtaatgcc ttaacagaat acttccgtgt
    35881 tgagaatctt gaaaacttgg atgaagtcaa gcgtgcagca gcctttctta tttacaagca
    35941 tggtccaatt gaccgtgtag aatcccacaa tgaatattgg cttgaaaacg atgcagccct
    36001 ccgtgaacaa ttcaacattt ttggtgctaa gcctaaacac ctgaaaaaga ccaaatttaa
    36061 gtctgaaatg aaaaaatatt tcaaaaaagc aggtgttcca gttgttccag gtgtggttgt
    36121 taaatcggaa cgtgattttg gcagagcttt gaagaatgtt ggttttccaa tgattgctaa
    36181 accagacaac ggtgttggag catcaggtgc cttcaaaatc gaaaataaag aagattttga
    36241 tcggtttgtg gagacatggg atggagcaac tatttatttc ctcgaaaaat ttgtcaattc
    36301 aagtattatc actacttatg atggtttgtt ggactacgaa ggcaatgttg tctttgaaac
    36361 aggcttgact tatgttcata ctccatttga attgatgcaa accaagaagg acaatgccta
    36421 ctttatcgaa aaagaattag attttaaact ggttgagtat ggcagagcta ttatcaaggc
    36481 ctttggtatg agagagcgtt ttttccatat tgaatttttc aaggatgggg acgactacat
    36541 tgccattgaa tacaataacc gtatggcagg cggtttcaca gttgaagcct ataactacgc
    36601 tcattccatt gatcttttcc gtgattatgc caatgtcgca acaggtggta cagttgagga
    36661 acgtagattt gaaccacaat actgcttggt agcaacccgc cgtgatacga ccgaatatgt
    36721 tcactcagca gatgatatcc atcagacatt cgctggtaag attaagacag tcaaacggat
    36781 gccagatgcc tttgcggaac ttcagggaaa tgatgcctat cttcttgtaa cggaaagcaa
    36841 gaaagagtta gatgaaatga ttgcttatat tggtctaaca aaataaaact aactgtaaga
    36901 cgccagaaat ggtgtctttt attctttcct tacaaagctg taagtttttt aatcagaact
    36961 gtaagagagt acaggaggaa tattttctat aatagactca taagaaatag aaagaaggaa
    37021 atcatatgtc attcaaattt ctacaagcaa agagaataga agaaaaggta ttctctgaaa
    37081 aagagaaagc tgaactcatg gaacaagcct tattcttaga agagctcgcc cataatttgc
    37141 aaagtatgcg atttatggca tactagaggg aggaaactat gaaaaagaaa gtaattagca
    37201 tgctggcttt gggaagcata atcctaactg cttgctcttc ctcttcagca ggttttagct
    37261 ttgatgaggg ctatcaaact ttccattaca agggaaaagt ctatgccgtt agcaaacagg
    37321 aagttgccga agatagtatt caaggaacag aagttcagtt tatggaatgg cctgttgtca
    37381 aagaagaagg ggcagtgaaa aagacagtat ccttgaataa tctctatgta accactaaca
    37441 aggaatgggc catcggtgtc caggatggtt actataaggt agatttagaa gaaaatgttg
    37501 ctgaatcaga ccgaatcgac tatcaaagtg tacttgagaa tgttgatttt acttaagaaa
    37561 tcaattagga gtttatatgt tattagaaat caatcattta aaaaaagttt acaaagacgt
    37621 taccactgtt gatattgaaa agattactgt acgagaagga gaaatctacg gctttcttgg
    37681 accaaatggt gcaggtaaga caactacgat gaaaatgatt ctatcacttg tcactccgac
    37741 ttcaggtgaa atttttatta ataaaaaaga cattcgaaat gacaaaaaat acctaaatca
    37801 gattggatct atgatagaag aaccgtccta ttatcctaat ttaactggat atgaaaattt
    37861 attagtgttt caaaaaatgg tgggatttga taaaaataat atccggccaa cattggagct
    37921 cgttggatta gctgatgaaa aaaatcgaaa aaaattagtt aaggcctatt ctcttggtat
    37981 gaaacagcga cttgccttag catttgcttt agtgaaaaag ccgaaaatct tattattaga
    38041 tgagcccaca aatggtcttg atccagctgg tattcatgaa attcgtgaat taattgttca
    38101 attagccaaa gaaaaaggtc tgactgtctt tatttccagt cacattcttc cggaaattga
    38161 acacattgca gatcgagttg ggattatcaa tcatggtcgt cttgtctatg agggagaaat
    38221 tgaagctatt aagtcaaata cttggattga aattggcggt gatttttcac agaaaaatat
    38281 tgttcagacc ttagttgaac ttggaacggt agaaattttg agtgcatccg aaagtcaagt
    38341 aactttaagg gatttggata acgatcggtt agcagatctg gtgagctatt taatagaaaa
    38401 tggataccga atattccgag tggttagaga aagtgaaact cttgaagata ttttcctaaa
    38461 tctaacaaag gaggcgtaag atgaatggtg tttacattga atggctaaaa agtagacgaa
    38521 caaaatctat ttcaattgtc attattttga tgttggttgc cacactttgg aatattgcaa
    38581 cttttatctc tgctttctct tcacatccag agttaagaat ggctggaacc ttgtttagta
    38641 atcagaatgt caatctactt atgttcccga ttgcagtttg tgtgtttgct agtcgaattg
    38701 tagggaatga acatgaaggg cagaccttta aactacaaat agctaatggt caaagcctaa
    38761 cagccatttt tcgtgataaa ttctttttta tgctggtttc ctttgttatt atgtctgcta
    38821 tcgaaattat gattatttat cttttcggaa cacaggcagg aatctctatt tctttgcaga
    38881 ttattggtat tcagtttatt gggcagatac ttgcaatatt ttcattgatt tgtctttatc
    38941 tgaccttggc catgattctt gaaaagcagg ggattctgct agcactagga cttttaggtg
    39001 gttttctagg aattatctta aacccaaaaa gttatggttt taccagttta cttaacccaa
    39061 tcactggttc aggaagtctt gcgccttata aatatcaatt tctgggtgac ggcacaatta
    39121 cctataattt agatagtcag ttgcttgaga aaatcgtctg ttatgccatt tactgcttga
    39181 tactctacct tttggcggtt ctaatattaa gaaagaaagg gaactaagat gaaagattac
    39241 ttcttagctg agtggacaaa aacaaggaaa attcaattat tagtcattgg gattgccttt
    39301 ttgagtttct ctagtatgat aggattgggt atctattttg ctaatcgtga tgttttaatc
    39361 gacggaactc aatctttggt tctgtgggga caactgacct tttacaatag taccttactt
    39421 tatcctccta tgttagccat tattgcaggt ctcttattag ttcctgaatt tgagcgaaaa
    39481 actcttgaca tgctaaaggc taatcaagtt tctatgagga aattatattt aggaaaatta
    39541 atgagcagtt ttcttcttat tcttccaatt caactcttat tgctgctgat ttttatagtt
    39601 gcggcaaaaa ttgacggcat ttcatttgac cttagtttag ccacacatgt taaatggatt
    39661 gctttatcgc ttttgtcttc ctttccaatt attacactcc aatcctatat cactgtaaaa
    39721 actcgaaatt tcagtaaggg agtcggtgtt gctaccattg gtagtatgct taattttgta
    39781 ttaattttta tcaatgaaag ttttacgaaa tttttccctt actctcaacc gatgattg
//
LOCUS       DBNFCO010000008        36727 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.008, whole genome shotgun sequence.
ACCESSION   DBNFCO010000008 DBNFCO010000000
VERSION     DBNFCO010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 36727)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36727)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36727
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.008"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            243..1049
                     /locus_tag="AC1PIV_000370"
     CDS             243..1049
                     /locus_tag="AC1PIV_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HIP6611423.1"
                     /translation="MQPTYNIDNPNLSYEAKQELWETGFGLQKVDGLTPSVYMEELAE
                     RQARGEYTYEQVYEEITKYHQSTDASTQEADIVSLRIVEMLSQNGFSLRPTTLLHIHK
                     ELFHDIFDSSIPVVEYRTVNITKNELVLKGDTVIYSDFPLIAATLDYDFQQERDFSYA
                     RLDKKAIVAHIQSFISGVWQIHPFREGNTRTITVFLIKYLRSLGFEIDNEPFQKHAKY
                     FRDALVLDNAKLVNKRSDFLTAFFENLLLNGQNDLSSERMYEELGLDEYQ"
     gene            1144..3852
                     /locus_tag="AC1PIV_000371"
     CDS             1144..3852
                     /locus_tag="AC1PIV_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TOTE conflict system archaeo-eukaryotic primase
                     domain-containing protein"
                     /protein_id="HIP6611424.1"
                     /translation="MSYYYEKLTGKVAKHLARFPYYATDKILNLMQFQDNNQQFLISD
                     KHLYDYFEEQKHQLSTDEKLSILFNLFKGRIDVYAKSYIDENGKINYFPSYNYGWKKR
                     PVEKRTCQPLTKQVLLAHLRGEISIGIFPMSLSDTCSFLAIDFDKNNWREEVSILRDT
                     AEQHGFEGHIEISRSGNGAHLWFFFEEEIACQQARNVGKRLLELAMQESKDIRFSSFD
                     RMFPNQDILPKGGFGNLIALPLQGEAFKKGRTVFVDKHFQPFSEQWTYLQQVQKIGQK
                     KILDFLGQEFSDTVDDTVLDCSLSNVIRVEKRAISSKTNYLLRKLASFPNPEFYLKQA
                     TRQPTYQTPERIYLFEETNEALHLPRGILAKLQEIFETVTIRDNRNSLSPIQISFKGR
                     LRFEQELALADLLASENGLLCAETGFGKTVLGAALIAQRKCRTIILVHNRQLLEQWLE
                     RLGEFLEIEEEEAVRYTPSGRVKVIGHIGQYGASKKWRSKLVDVVMIQSLFQLDVISD
                     FLSDYDMMIVDECHHVTALQFEKVVAQFASQYLYGLTATPECKNGHQPIVFQRIGPIL
                     HTAQSGQYDFKKRLLLHLTSFGKLDLEQSNSTNFASLNDWLAKDLHRNTLIVQDIFKL
                     YQEKRNILVLVNRREHIELLEKLLIEKEMPNIFCLSGASKRRDTKELLKRISELDENS
                     PFVLISTGKFIGEGFDMPKLDTLILAAPLSWKNNLIQYAGRLHRPYQGKTEVRIVDYL
                     DIHVPYLERMYQKRQIAYRKMAYQVGEKEQTQVLFSGRDYEEKFREDLRNTRSTVYLQ
                     LHSFTSSRIQELLGLLRGKQVVIHVSKNHKLSEWLMGLNSDNVKVKLVPERIGTTAVI
                     LDSNLVWYGNLSPFTYQSDDQASLLRLESQSIATELLEKFENSNIK"
     gene            3968..4690
                     /locus_tag="AC1PIV_000372"
     CDS             3968..4690
                     /locus_tag="AC1PIV_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012774992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611425.1"
                     /translation="MEKEVFTPDQSQSIVDAILKGYKSYLDERIEKRRTMHVSAGYVW
                     TKANHIDGALATANLNFIDKFELKHASQSWEFLEFNSENQLLGRVCFVLKGLTRLRQV
                     FPTAVKSGKGYLFDYAQINTSYLENLSRHTDESTLFPVQMELFDDNLFELLNRSEQSI
                     NNFFFITYQADELHHLTNIQVIMPDSRTGKLIEIQNLSTFISTSNVDFNDEKYQELQG
                     LSEIDDVADFEIIPRLASEKEA"
     gene            4703..5857
                     /locus_tag="AC1PIV_000373"
     CDS             4703..5857
                     /locus_tag="AC1PIV_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HIP6611426.1"
                     /translation="MFNGSRLEELRLLNGLTRADLARELEVTEQAIWQFETGVTLPKM
                     KNKIAMARFFQVEVDYFDAVDKNGSFSLSRIAFRNADLEAKKNIHIQMVYLEKMNQMI
                     DYLENFVSIPNQIIYQLVDSIEQKLQQHESLEFIADHVREVLAVSVDNANLLYSLEKS
                     GIYISERLINGNADAYSAWSRNGRPFIVLGLGKSAVRHNFDLAHELGHLLLHNQVDFE
                     ELSKEELEEKEKEANQFASYFLLPRKQFLMDFVNIVGKRVSNPDQYILLKKRFGVSIQ
                     ALEYRAYKLGLLTPQQNSYFYRQISKKGYKAVEPLDLEIPLKKPSKIRSILDVILSNN
                     LLTLSDIERNQRVSKNFISQLFSFDVKFFDKYLLQLDTFDNVIPLFSRKQ"
     gene            5872..6930
                     /locus_tag="AC1PIV_000374"
     CDS             5872..6930
                     /locus_tag="AC1PIV_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012774994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HIP6611427.1"
                     /translation="MNKINSYKIHLPSLLPFGFLFANNCYTYREVFMEGQFEAVVEVD
                     EAGQLSSYVWDCEMEEVYTAHLVTAPSGAFVGQVRESYQSILDRVEEACCIALPFTKD
                     QSNRIAQLIKEQWGDLPDYPFAKLPTYGAFRHPNNNKWYALVSQIPRDKLDGSGSQEE
                     VEIVNLKVAGREIAELLSRSGIFPAYHMSKKTWVSVLLDDTVEDQTVFALLEKSRYLV
                     GPKSYKATQGPDYWVIPANPKVYDIDTEFAENKVVYWPQKSTIQVGDIVAIYVTAPVQ
                     AIRYVCRVLGENLENHGESDIPTEKKLMQVELLAQFSDDVLPRARMMDLGVKAVRGPR
                     RLTKELIDVLTSEVINIY"
     gene            7014..8006
                     /gene="asnA"
                     /locus_tag="AC1PIV_000375"
     CDS             7014..8006
                     /gene="asnA"
                     /locus_tag="AC1PIV_000375"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004071 - aspartate-ammonia ligase
                     activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HIP6611428.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEIVEVQGPILSRVGDGM
                     QDNLSGVENAVTVNVKLIPDATYEVVHSLAKWKRHTLARFGFHEGEGLFVHMKALRPD
                     EDSLDPIHSVYVDQWDWEKVIPDGRRNLAYLKETVEQIYKAIRLTELAVEARYDIESV
                     LPKKITFIHTEDLVKNFPDLTPKERENVVAKEYGAVFLIGIGGELADGKPHDGRAPDY
                     DDWTSPSEAGYKGLNGDILVWNEALGSAFELSSMGIRVDEEALKRQVAITGDEDRLEF
                     DWHRALLNGLFPLSIGGGIGQSRLAMFLLRKKHIGEVQSSVWPQEVRDNFENIL"
     gene            8139..9986
                     /gene="typA"
                     /locus_tag="AC1PIV_000376"
     CDS             8139..9986
                     /gene="typA"
                     /locus_tag="AC1PIV_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002932699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HIP6611429.1"
                     /translation="MTKLREDIRNVAIIAHVDHGKTTLVDELLKQSQTLDERTQLDER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQNLTPIVVVNKIDKPSARPEEVVDEVLELFIELGADDDQ
                     LEFPVVYASAINGTSSLSDNPADQEETMAPIFDTIIEHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERKEIQEAKAG
                     DLIAVSGMEDIFVGETVTPTDAVEALPVLRIDEPTLQMTFLVNNSPFAGREGKWVTSR
                     KIEERLLAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IIKEIDGVKMEPFERVQIDTPEEYQGSVIQSLSERKGDMLDMVATGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPVVQGEIGGRHRGALVSIDQGKATTYSIMR
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITTAKQMTNVRSATKDQTSVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAERDKAAKKKKLATEE"
     gene            10004..10252
                     /locus_tag="AC1PIV_000377"
     CDS             10004..10252
                     /locus_tag="AC1PIV_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HIP6611430.1"
                     /translation="MFYLILAIMLVLFYIFIAPSNIKGTMNLIAAVFLLVALAIALVL
                     GFLRIMQFPKEIWVGLLMILIGFWAMRDIYQLNDDTKF"
     gene            10959..11219
                     /locus_tag="AC1PIV_000378"
     CDS             10959..11219
                     /locus_tag="AC1PIV_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein"
                     /protein_id="HIP6611431.1"
                     /translation="MDVKNLRKLKRIELYEIMLAQSEEIDCLRNQLEKIKTELADRRI
                     MISQSGSIAEASMKLTNIFEEAQKAADLYLYNVKNKIGDVHE"
     gene            11212..11802
                     /gene="lepB"
                     /locus_tag="AC1PIV_000379"
     CDS             11212..11802
                     /gene="lepB"
                     /locus_tag="AC1PIV_000379"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012774995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HIP6611432.1"
                     /translation="MNSSNLKGKELPKTSELKELYQHERYRHTFWRTVKSTVFMLVVV
                     AAFAILIAVLFLPILRIYGDSMKGTLNSGDIVVSVKSNDFESSDVVAFYYNNNILVKR
                     VIAEAGDWVDMDKQGNVYVNNQRLDEPYLANRDYGHTDIEFPYQVPENRIFVMGDNRK
                     ESIDSRNNAIGTVSNEQIVGKLVFKIWPLSELGWIE"
     gene            11834..11983
                     /locus_tag="AC1PIV_000380"
     CDS             11834..11983
                     /locus_tag="AC1PIV_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease G"
                     /protein_id="HIP6611433.1"
                     /translation="MRDWLNLEKIQGWRRKYKKLVNIIAFLVVFATTYALILPAITLD
                     QEKAE"
     gene            11999..16810
                     /locus_tag="AC1PIV_000381"
     CDS             11999..16810
                     /locus_tag="AC1PIV_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="InlB B-repeat-containing protein"
                     /protein_id="HIP6611434.1"
                     /translation="MQETPVTTEISKLTEPMVTTQQTPIVGSSADEVQSPATETVPDP
                     AEQVSTESASKPQTDQERITEPTTIVHKTNDYEVTATFDASAQFPKDVEFNVRELDSQ
                     SEEYRTHYEKTKEKLGVKKLVYARFFDIHFSSQGQEVEPASPVKITIRNKELVQRPDD
                     SKLKIVHFEENSQIEVLEAETKENEQQISEISFDASHFSVYGDVLANYYTVKFTYTDT
                     AGQEQVITSLIDKTVGTSLGSLPEAPFKNGYVFSHWINKDTGDRIDENTVITGDLTAV
                     AVFNNINIYTIDVTYFYHNVSKNQDITIDKETVQLEASDAPYQLTPPASTEVSNKEDT
                     TLPADAIYYPEKPLLEFTADQLERLDVADGVDDNYISERVQYVPYNAEYDVIYRLKNL
                     TGSGYSDIQTVHVRGVLGSTVTPQILTYNYADFERADTAKIENTSGQKLYVYYTRKTF
                     TLSYNSNGGSNIPQQQGLYDSQIKISTTTPTKEGYTFEGWYDNPGLTGNKITGSLTLK
                     KDTTLYAKWTPNRVRYIIGYYKEVYDNNTGTTSYVYDSSAAGWGLVGTTVKGTDSNIG
                     PPPPTQTTIGSIGYEKDVTKSAASSIEIAADGTSVLKVYYKLKRYTFEFFLNDNNANI
                     TINGKTYSDRNRYMIRDVVLGQDVSKLWPASITNPKEVYDDKVYYDSYGRPIRYFFDY
                     WIFGNLLFKTDRFEVVESMLPTSGTTSKFTAYWNTQGTQANVEYWLQQPDGSYKKSDI
                     YSQSFLKTAGLLPKEIFGYSYYTDASFTEAGIRYYGTQGNTYRFYYKRQAFKIDYYYN
                     STGLDSKSNILFESNINTATYNYQPPRSTGVDADYTWGGWYTDSLLTEKYNFNKMPAN
                     NLVLYAKWIAPKFKVTFDINGGNGTAPVDQSVEKYKYAKAPADPTREHYNFLGWSTED
                     GKLYSWSDQVTKDVKLTAKWELKPLTYTVRYLEAGTNTQLAADKVITSPALVLNQAIT
                     EKALGITGYRPDKSSQTINLNFRGNEITFYYTPKVKDVVYTIKYVLKDNPAIEVAPTV
                     TRKVDGSIIRAKEAAADVNKQHLQSQSGVTAEMLEMDYYPTVNTQSLILTSSDANNVI
                     VFEYVGFDTQTFTVNYLDMDGKKIDGQEPLVVYRKKPGSFVVDHKTINGYTYDHSLDS
                     ENAADKTVYRVSKGGHITIDLYYKKNLTLTALDKSKVYDGTALSSSGLSDLNPSYSSE
                     LKTGDKLVAISYDGSQTNAGSSATTPKLANISNASGADRTNFYHITYQPGNLRVDQQP
                     VVVVIDGEKKSKIYDGKAEAVGYKVTEIRDSSGLYKKTDIKFNGSSSEQSVKKKDAGI
                     YPLLLSNRFSNTNQNFQVDFLISDGELRIDRRQLTITSDSASKAYDGSELRADNITVS
                     VPAGVDYTGFVDGEGIIPTFLGGPIDSGMMPNFFEYALKSGTNLANYELDIQFGQLKV
                     KEVIKIQKTDLAWQALSGGKFELTKWDGLNWAQVDGVQEFAITSKDGIRIPVGLEAGR
                     YRLQELAAPDGFIVLDSYIYFSIKEIFNEDKTSSFYTVSLSDEAGKDASPERATLTKV
                     SGDASHRIQVANEQGRALPSTGGDGQKWFILSGLVLIAISYLMHLFVQRRR"
     gene            16917..18359
                     /locus_tag="AC1PIV_000382"
     CDS             16917..18359
                     /locus_tag="AC1PIV_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HIP6611435.1"
                     /translation="MKKLQQFFTSLVAVLTVFAFGSTALAQTVDSGKSGAGTITVSNA
                     SQGQTYTAYKLFDATVTTDGSGISYKLPAGKIATNFGGDTWFEVDSKGNITAKEGATV
                     SSEAFAAWAKNFGTEVTSATANDNSLVFTHLTFGYYFVTSSLGAVLTVDSTTPNATVI
                     DKNTTNPTIPDSNNGGGKKILSNGATTSETTAKIGDTINFQIKFNATNYVTKDRQTKQ
                     IVSYTIEDSPTALAIDQNSVNVKVDGVDITAKISKTFDATGKMNLVITWADAAASNKT
                     IYNSPAEVIITYSAVVTKDAKEGEATNSATIGYNTIDNPTTPPTPVDPDKPTETTKVT
                     THRFTLKKTNNVGETLTGAEFKLYDAANNGTEIKVVKESDGVYRVAQADEQGVVIEAG
                     EVVIKGLKHSTTYYLEEMKAPNGYNILTERQSIEVKENNTAQANIVNKKGGVLPSTGA
                     IGTTLFYLVGSILLLVALVYTISKRRMNNI"
     gene            18473..19342
                     /locus_tag="AC1PIV_000383"
     CDS             18473..19342
                     /locus_tag="AC1PIV_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HIP6611436.1"
                     /translation="MIKWLKKKGPSFIMPLIFILGIGLLAYPSVSDYWNSFHQSEAIM
                     SYSDTVSDMTADQYKEIIDSARQYNQEKPLNWNVTASDIEAYNQELNFNKDGIMGYIE
                     IPKIDVKLSIFHGTDETVLETSIGHLEGTSLPVGGLGTHSVLSGHRGLPSARLFSDLD
                     KLREGDIFTIHVLNETLTYKVDQIRVVEPSDLSALTMEPQKDLLTLVTCTPYGINTHR
                     LLVRGYRIENVNGSALVTSDAIQIKAIFIAPFIATPILFVILIYIFITTSKTFRSRNR
                     NQVLDDFLVPKKF"
     gene            complement(19456..19743)
                     /locus_tag="AC1PIV_000384"
                     /pseudo
     CDS             complement(19456..19743)
                     /locus_tag="AC1PIV_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000018958.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
     gene            19914..21263
                     /gene="murD"
                     /locus_tag="AC1PIV_000385"
     CDS             19914..21263
                     /gene="murD"
                     /locus_tag="AC1PIV_000385"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HIP6611437.1"
                     /translation="MKMIDIVKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     ENPTAQSLLEDGIRVICGSHPLELLDEDFALMVKNPGIRYDNPMVEKAIGKGIPVWTE
                     VELAYLVSDVPIVGITGSNGKTTTTTMIAEVLNAGKKPAKLCGNIGYPASSVAQTATA
                     EDTLVMELSSFQLMGTESFHPHIAVVTNLIASHIDYHGTFEDYVAAKWMIQRQMTAED
                     FVVINFNQKEAKELAGQTKATVVPFSTQEVVDGAYLADGKLYFKGEYIMDADQIGVPG
                     SHNVENALATIVVAKLLGVDQQAIQESLSAFGGVKHRLQFVGEINGVSFYNDSKSTNI
                     LATQKALSGFDNSKVILIAGGLDRGNEFDELVPDLVGLKKMVILGQSAPRVQRAADKA
                     EVETIEALDIADATRKAFAIAEKGDIVLLSPANASWDMYANFEVRGDVFLQTFEELK"
     gene            21266..22330
                     /locus_tag="AC1PIV_000386"
     CDS             21266..22330
                     /locus_tag="AC1PIV_000386"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA];
                     GO_function: GO:0051991 -
                     UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-
                     glutamyl-meso-2,
                     6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol
                     4-beta-N-acetylglucosaminlytransferase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0007049 - cell cycle [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0030259 - lipid glycosylation [Evidence
                     IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HIP6611438.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLIPRFLEEGWEVHYIGDGNGIEHE
                     QVVKSGLDVHFHSIATGKLRRYFSFQNMLDVFKVGFGVLQSLTIIAKIRPQALFSKGG
                     FVSVPPVIAANLLRVPVFIHESDLTMGLANKIAYKFATTMYSTFEQPASLTKVKHVGA
                     VTKVGQTNDKVTPIQLPEILSHFDKSLPTLLFVGGSGGAKVFNDLISQNSAALTERFN
                     IINLTGDSSLNKLDKNLYRVDYVTELYQPLMDLADVVITRGGSNTLFELIAMQQLHLI
                     VPLGRQASRGDQIENALYAEKKGYSKQIDESQLTFASLLVEVDELLKHKEFYVQNMAN
                     SNEIQSVDSFYNLLREDMGR"
     gene            22336..23418
                     /locus_tag="AC1PIV_000387"
     CDS             22336..23418
                     /locus_tag="AC1PIV_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002943031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HIP6611439.1"
                     /translation="MTEKDSNVEESVLEVEQASQVELDSEQISPAEKESVLAEEKEFS
                     TDVDIPEMTAPDDEKSAFFEQWKARHQAYLAHKDEADIQAVDEGQTEQEIPEAKKSKR
                     VLFQGIERKTESLKSKKETGEKVQTLKVDIPSKVVWKAIPVLVTSLLLAALALYFISP
                     TSKKKQIEVVGNERLTAEQVENYSLISPDDYNVTIALHADAYAKNIKKNSSSVETATI
                     KFQFPATFTIHIKEYAIIGYIQQQSQWYPVLSSGEIGGEPISQDSLPEDYTTINLSDK
                     ELIKELAIELGKIDAGIRSAIQTINLTPSKVTADLLTFNMRDGNTVLVPLSEISQKVS
                     YYTKIAAEVTVPTTIDMEVGIYRYAS"
     gene            23571..24950
                     /gene="ftsA"
                     /locus_tag="AC1PIV_000388"
     CDS             23571..24950
                     /gene="ftsA"
                     /locus_tag="AC1PIV_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002943036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HIP6611440.1"
                     /translation="MARNGFFTGLDIGTSSVKVLVAEYIDNEMNVIGVSNVKSAGVKD
                     GIIVNIEVAAGAIKKAIEQAEEKSGIRIEKVNVGLPANLLQIEPTQGMIPVTTDSQEI
                     TDLDVENVVKSALTKSMTPEREVISFIPEEFTVDGFQGIKDPRGMMGIRLEMRGMLYT
                     GPRTILHNLRKTVERAGVQVENIVISPLALTRSVLNEGEREFGATVIDLGGGQTTVAV
                     MRGQELQYTNIYQEGGDYITNDISKVLTTSKSIAENLKYNYGIAYPQDASDKEKFTVE
                     VIGENAPVEVTERYLSEVIAARLRQIFDRVKQDLERTRALDLPGGIVLVGGGAILPGI
                     IELAQEVFGVNTKLFVPNQIGIRNPAFASVISFVEYVGELEDVENIAQHAVNGETTLR
                     HKPVEIPVARPRISQPIQREIVNELNTVDQVEEQVAPTYHDEEEEVRPAAKGNITDRI
                     RGLFGSMFE"
     gene            24976..26205
                     /gene="ftsZ"
                     /locus_tag="AC1PIV_000389"
     CDS             24976..26205
                     /gene="ftsZ"
                     /locus_tag="AC1PIV_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HIP6611441.1"
                     /translation="MAFSFEAAASHGAVIKVIGVGGGGGNAINRMIEEGVAGVEFIAA
                     NTDVQALSSSKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEEALTNVLTGADMVFI
                     TAGMGGGSGTGAAPVIARIAKNLGALTVAVVTRPFGFEGNKRGNFAIEGIEGLREQVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MENKGNALMGIGIGTGEDRVIEAARKAIYSPLLETTIDGAEDVIVNVTGGYDMTLTEA
                     EDASEIVNQAAGQGVNIWLGTSIDETMKDEIRVTVVATGVRQDTADKPARHRTEAVSP
                     RPSHRFDHSVASAPTRGAAQQTEAPKASAFGEWDLRRENLIRPTDTEPTSTVSVEKFT
                     MDQDEDELDTPPFFRNR"
     gene            26212..26883
                     /locus_tag="AC1PIV_000390"
     CDS             26212..26883
                     /locus_tag="AC1PIV_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HIP6611442.1"
                     /translation="MNFQKNKDAIFSAVAKAAEKAGRPSESVKVIAVTKYVDSSIANQ
                     LVNTGITHIGENRVDQFLEKYNALADKQLTWHLIGTLQRRKVKDIIPFVDYFHALDSV
                     KLAQEIDKRATKIVKCFLQVNVSGEESKHGFAVSEIDAALAEISLLENIELVGLMTMA
                     PIDATDDELDEIFSKMQEIQEELATRNLPRMPFTELSMGMSGDFERAIAHGATYVRIG
                     SAFFE"
     gene            26900..27463
                     /locus_tag="AC1PIV_000391"
     CDS             26900..27463
                     /locus_tag="AC1PIV_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012774998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000917 - division septum assembly
                     [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA];
                     GO_process: GO:0090529 - cell septum assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HIP6611443.1"
                     /translation="MALKDTFKNLFNYFEVDEVNEVEEQADAYSMPNDRPKMRVANTT
                     VAPVREQQPKVETRREARSESQLQRLHERQQELMTNNNEKEIVKTTIDIKFPKRYEDA
                     PEMVNLLLDNASILIDFQYMSEQQARRCLDYLDGARSVLSGNLKKVSNTMWLLTPVNV
                     TVNIEELRNAGTTTGVADSNFEFDIKR"
     gene            27468..27731
                     /locus_tag="AC1PIV_000392"
     CDS             27468..27731
                     /locus_tag="AC1PIV_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HIP6611444.1"
                     /translation="MQILIFLLLKIVEIYSYLLLAYALLSWFPSLYTSSIGRLIQWLV
                     APILKPFRRLNLQFMGLDWTVMAAMIALNMGTRFLVQLLLLLA"
     gene            27734..28525
                     /locus_tag="AC1PIV_000393"
     CDS             27734..28525
                     /locus_tag="AC1PIV_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HIP6611445.1"
                     /translation="MKNDKNLLQHFSREEREFVEKIMDMCQQVEDTYSYRLTHFLHPR
                     QDEIVCKIANYYQLQTFSSRDLVSTEHSRVIIAPTYYELDIKDFELTALHLSYARKFH
                     TLSHSQVLGTFLNQLGIKREYLGDILIDDERLIVFIDQKFGQIALQSITKVARVPVKG
                     KEEEWTTVRLPIGQEWRSKDVLVSSMRLDKLISVAFNLSRATANKLIEAGHVKLDYVL
                     TEQTSKLVEIGQLISVRRYGRVRLNEFLGFSKQGKIKLKLDIVKT"
     gene            28534..29223
                     /locus_tag="AC1PIV_000394"
     CDS             28534..29223
                     /locus_tag="AC1PIV_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HIP6611446.1"
                     /translation="MALTALELKDKTFATKFRGYDADEVDDFLDIVTRDYEDLIRKNH
                     DQELELKNLRERLAYFDEMKESLSKSVLLAQDTAEKVKVAAEDQAANIIKQADYDAAT
                     LLHEAKDKANEILRNATDNAKKVVIETEELKNQTRIFHQRLKSTVESQLSLVNSSEWE
                     EILRPTASYIQTSDEAFRDVLHKALDEELPVEEESLDYTRQLTPEEIAELTRQAAAFE
                     SGESVVLSIEE"
     misc_binding    29230..29431
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            29453..29896
                     /locus_tag="AC1PIV_000395"
     CDS             29453..29896
                     /locus_tag="AC1PIV_000395"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIP6611447.1"
                     /translation="MIRLELVNKDNFEVVLQVQLASEDQRRVASVEYSLAQAWLYKDS
                     GMILPYAVVSGRKVVGFAMLSIEPKDNSYYLWRLLIDKDFQNRGCGKEAIQQIIGKAK
                     ADPLCHKISINYVIGNHKMRYILEKIGFQSVGLEGQEMKMELIIK"
     gene            29907..32696
                     /gene="ileS"
                     /locus_tag="AC1PIV_000396"
     CDS             29907..32696
                     /gene="ileS"
                     /locus_tag="AC1PIV_000396"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002943049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HIP6611448.1"
                     /translation="MKLKETLNLGKTAFPMRAGLPTREPEWQKAWDEANLYARRQELN
                     EGKPAFHLHDGPPYANGNIHVGHALNKISKDIIVRSKSMSGFRAPFVPGWDTHGLPIE
                     QVLAKQGVKRKEMDLVEYLEMCRDYAFSQVDKQRDDFKRLGVSADWENPYITLTKDYE
                     AAQIRVFGAMADKGYIYRGAKPVYWSWSSESALAEAEIEYHDIDSTSLYYANKVKDGK
                     GLLDTDSYIVVWTTTPFTVTASRGLTMGADIDYVLVQPAGSDRKYVLAEALVDSLAAK
                     FGWESFEVISKHKGAEFEYIVTEHPWDREVDELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGVKYDLEVAVTVNERGLMNEAAGPDFEGQFYDKVVPTVKEKLGDLLLASEVINH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDQIEATTFNPSWGKTRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTKEVTDHVAALFEEHGSIIWWKSDAKDLLPAGF
                     THPGSPNGEFTKETDIMDVWFDSGSSWNGVMNARENLAYPADLYLEGSDQYRGWFNSS
                     LITSVAVNGHAPYKAILSQGFVLDGNGMKMSKSLGNTILPSDVEKQFGAEILRLWVTS
                     VDTSNDVRVSMDILGQVSETYRKIRNTLRFLIANTSDFNPASDAVAYEELRSVDQYLL
                     VKFNKLVVQIREAYDNYDFMGIYKSVVNFVTLDLSAFYLDFAKDVVYIDGAKSLSRRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEHEAEEFVQLAEMPEVETFANEAQLLA
                     DWENFMVFRTQAQKALEEARNAKVIGKSLEAHLTAYVSAETKSFLESLNADLAQLLIV
                     SNLTVTTETAPSTALVVDEVAFAVERAAGEVCDRCRRIDTSVAERSYGATICDHCASV
                     VEENFAEAVAQGFEA"
     gene            complement(33075..33383)
                     /locus_tag="AC1PIV_000397"
     CDS             complement(33075..33383)
                     /locus_tag="AC1PIV_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HIP6611449.1"
                     /translation="MKIINTTNSHPNLVQSQLANTDAFLVETYSAGNTDVIFTQAPRH
                     YELLISNKYRAVQQNEIEQIRDFFLHRKIDERTINKAAIQTIHTDRLIEMSIPIIAEV
                     "
     gene            complement(33438..33899)
                     /locus_tag="AC1PIV_000398"
     CDS             complement(33438..33899)
                     /locus_tag="AC1PIV_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HIP6611450.1"
                     /translation="MEKIAVFGEKKAGVSYQSRFGVYAVIPDEKKEQIILVQAPNGAW
                     FLPGGEIEKGENHLIALERELMEELGFTAEIGKYFGQADEYFYSSHRDTHFYNPAYIY
                     EVTSYHQIGQPLEDFNHIAWFPVNEAIDKLKRGSHKWGIEQWKLQENSFNN"
     gene            complement(34085..36313)
                     /locus_tag="AC1PIV_000399"
     CDS             complement(34085..36313)
                     /locus_tag="AC1PIV_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HIP6611451.1"
                     /translation="MLCKNCNINDATIHLYTNLNGKQQQVDLCHNCYQIMKTDPHNAI
                     LRGLGDLTNPNNMDPFSEFFNHLGGYPGNTPAGKNREQTPPTQAGGHNGRGGQTPPPQ
                     QPQQPNGLLEEFGINVTEITRRGDIDPVIGRDQEITRVIEILNRRTKNNPVLIGEPGV
                     GKTAVVEGLAQKIVDGDVPQKLRDKEVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRN
                     RREIILFIDEIHEIVGAGSAGDGNMDAGNILKPALARGEMQLVGATTLNEYRIIEKDA
                     ALERRMQPVKVEEPSVEETITILKGIQNKYQDYHHVKYSDAAIEAAAVLSNRYIQDRF
                     LPDKAIDLLDEAGSKMNLTLNFIDPKEIDQRLIDSENRKAQATRDEDYEKAAYFRDQI
                     AKYKEMQKATISEEDIPLITEKEIEAIVEQKTNIPVGDLKEKEQSQLVSLASDLKAHV
                     IGQDEAVDKIAKAIRRNRVGLGAPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSADS
                     MIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLILLDEVEKAHPDV
                     MHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAAMEGRTQSVLG
                     QLSNFFTPEFMNRFDGIIEFQPLSKENLLEIVSLMLDDVNKRLSHNGISLHVTDKVKE
                     KLVDLGYNPKMGARPLRRTIQDQIEDAITDFYLEHPAEKDLRAVMSSKGTIQIKAQTK
                     TK"
     gene            36537..>36727
                     /locus_tag="AC1PIV_000400"
     CDS             36537..>36727
                     /locus_tag="AC1PIV_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1797 family protein"
                     /protein_id="HIP6611452.1"
                     /translation="MESHLVRIINRLEAMANDGGTLKRNFERDGIVVAEVAYSYDEEN
                     GSVFTLRDVAARETYAFDS"
BASE COUNT        11301 a         6617 c         8118 g        10691 t
ORIGIN      
        1 tataaataaa ttttaagagc tccattggac atagaaaaac ttgagatttt atcaagcgtt
       61 accaatctgg aaatcgtcta aaaataaaaa caagctgact accaagcaaa atatgatgcg
      121 acacaggagc ggattgaaga gatgaaaaaa ctggttaagt aggtagaata caacaaatgc
      181 ccagcctaaa aaggctgggt tttgtggtat aataaggtta gaaattcaaa caggaggagt
      241 ctatgcaacc aacttacaat attgataatc ccaatctttc ctacgaagcc aagcaagaac
      301 tctgggaaac gggttttggt cttcaaaaag tggatgggtt gactccgtct gtttatatgg
      361 aggagttggc ggaaaggcaa gctcgtggag agtacaccta tgagcaggtg tacgaggaga
      421 ttacgaaata ccaccagtca actgacgcca gtacgcaaga ggcagacatt gtctctctcc
      481 gaattgttga aatgctctcc caaaatggtt ttagcctccg accaaccact ctcttacata
      541 tccacaaaga gctctttcac gatatttttg acagcagtat tccagtagtt gaataccgca
      601 ctgtcaatat tacaaaaaat gaattagtct taaaaggtga tacagtgatt tattcagatt
      661 ttcccttgat tgccgccact ttggactatg atttccagca agaaagggat ttttcttatg
      721 ctaggttaga taaaaaagcc atcgtcgctc atatccaatc ctttatttca ggtgtttggc
      781 aaatccaccc attccgtgaa gggaatactc gaacaatcac cgtatttctc atcaaatacc
      841 ttcgctcact tggttttgag attgataatg agccttttca aaaacatgca aaatatttcc
      901 gtgatgcgct tgtacttgac aatgctaagt tagtcaataa acgctcagat tttttaactg
      961 ccttttttga aaatctcctc ttgaacggtc agaatgattt atcaagtgag aggatgtacg
     1021 aggagttggg gttagatgaa tatcaataaa gacaggatag ttttcaagtc ggaaatagac
     1081 cagtgaatac ttgggctttt gacttttcgt tgataatctc gttaggcaat ttggagaaat
     1141 cgtatgtcct attattatga aaaattaacg ggtaaggttg caaagcatct tgctcgtttt
     1201 ccctattatg ctaccgataa gattctgaat ttaatgcaat ttcaagataa caatcagcaa
     1261 tttctgataa gtgataagca tttgtatgat tactttgaag aacaaaaaca tcaactaagt
     1321 accgatgaaa aactctccat tctgttcaac ctatttaagg gacgtataga tgtttatgcg
     1381 aaatcttata ttgatgaaaa tggaaaaatc aactattttc cttcttacaa ctatggttgg
     1441 aaaaaacgtc ctgttgaaaa gagaacttgt caaccattga ccaaacaggt attattggct
     1501 cacctacgtg gcgaaatcag tattggtatt tttccaatga gtttatcaga cacgtgttcc
     1561 tttttggcga ttgattttga taaaaataat tggagagaag aggtctccat tctaagagat
     1621 acagcagaac aacatggttt tgaggggcat atcgaaatct ctcgttcggg caatggtgct
     1681 catctctggt ttttcttcga ggaagaaatt gcttgtcagc aggcgagaaa tgttggaaaa
     1741 agactgctgg aattggctat gcaggagtca aaagatattc gcttttcttc atttgaccgt
     1801 atgtttccaa atcaagatat tctgcccaag ggaggatttg gcaatcttat cgcactgccc
     1861 ttacaagggg aagctttcaa gaagggaaga accgtttttg ttgataaaca ttttcagccc
     1921 ttttctgaac aatggaccta tcttcaacag gttcaaaaga ttggacagaa gaaaattcta
     1981 gatttcttag gacaggagtt ttcggatact gtagatgata cagtattaga ttgtagctta
     2041 tcaaacgtta ttcgagttga gaagagggct atttcttcaa aaacaaatta cttattgaga
     2101 aagctggcat cttttcctaa ccctgaattt tatctaaaac aagcgaccag acaaccaacc
     2161 tatcagactc cagaacgcat ctatttattt gaagaaacaa acgaagcctt gcatcttcca
     2221 agaggaatac ttgctaagct acaggaaatc tttgaaacgg taactattag ggacaatcgc
     2281 aacagtttat ctccgattca gatttctttc aaagggaggt tgcgttttga gcaggaactt
     2341 gctttggcag atttattagc tagtgagaat ggcttgctat gtgctgaaac aggtttcggg
     2401 aagacagttt taggggcagc cttgattgcc cagaggaaat gtagaacgat tatcttagtt
     2461 cacaatcgtc aactgttgga gcagtggttg gaaaggttgg gtgaattttt agagattgaa
     2521 gaggaagagg cagttcgcta tactccttca gggcgtgtaa aagtaatagg gcatattggg
     2581 caatatgggg cttctaaaaa atggaggagt aaattggtgg atgtggttat gattcaatcc
     2641 ctcttccaat tggacgtgat ttccgacttt ttgtcggact acgatatgat gattgtagat
     2701 gaatgccatc atgtgacagc cttgcagttt gaaaaagtag ttgctcaatt tgctagtcaa
     2761 tatctatatg gcctaacagc aacgccagag tgtaaaaatg gacatcaacc gattgtcttt
     2821 cagcgtattg gtccaatttt acatactgct caatcaggtc aatacgattt taaaaagagg
     2881 ttactactcc atctaacatc ttttgggaaa ttggacttgg aacagtcgaa tagtacgaac
     2941 tttgcatccc ttaatgattg gcttgccaaa gatttacatc gtaatacttt gatcgtgcaa
     3001 gatattttca aactatatca agaaaaacga aacatccttg tcttagtcaa tcgacgggaa
     3061 catatagaat tattggaaaa gctacttatt gaaaaagaaa tgcccaatat tttttgtctg
     3121 agtggagcga gtaaaagaag agatacgaaa gaactcctga aaagaatcag tgagctagat
     3181 gagaatagtc catttgttct catttcaaca ggaaaattta ttggagaggg cttcgatatg
     3241 ccaaagttgg atacattaat tttggccgct cctttgtctt ggaaaaataa tctcatacag
     3301 tatgcaggac ggcttcaccg tccctatcaa ggcaaaactg aggtgagaat agttgactat
     3361 cttgatatac acgttcccta tcttgaaaga atgtaccaga aacgtcagat agcctatcgt
     3421 aaaatggcct atcaggttgg agagaaagaa caaacccaag tattattcag tggtagggac
     3481 tacgaggaga aatttagaga ggatttgcgg aacacacgtt caacagtcta tttacaattg
     3541 cattcgttca cttctagtag gattcaagaa ttattgggac tgctccgagg aaaacaagta
     3601 gttattcatg tttccaaaaa tcataagtta agtgagtggc taatggggtt aaacagtgac
     3661 aatgtaaagg tgaagcttgt accagaaagg attggtacga ccgcagttat cttagatagt
     3721 aatctcgttt ggtatggcaa tttatccccc ttcacatatc agtcggatga ccaagctagt
     3781 ttgttgagat tggaaagtca atctattgca actgagttgc ttgaaaaatt tgagaattca
     3841 aatattaaat aaaaaaatcc gaatactgtt ctgttcggat atttctttaa aaaaagaact
     3901 gtatttgtat taaaatttaa tattttgtat aaaaaatatg ataaaataat gagaaatgga
     3961 ggtgcatatg gaaaaagaag tgtttactcc cgatcaaagt caatctattg tagatgctat
     4021 attgaaggga tacaagtcct atcttgatga gcgaattgaa aagagaagaa caatgcatgt
     4081 ttctgctggt tatgtttgga ctaaagctaa tcatatagat ggtgctcttg cgactgcaaa
     4141 cctaaatttt attgataaat ttgagttgaa acatgcgagt caatcttggg agtttttaga
     4201 atttaactca gaaaatcaac tattaggacg tgtatgtttt gttttaaaag gtcttactcg
     4261 cttgcggcag gtttttccaa cagcagtaaa aagtggaaag ggctatttat ttgactatgc
     4321 tcaaattaat acaagttacc tagaaaatct ttcaaggcat accgatgaaa gtacgctttt
     4381 ccctgttcag atggaattgt ttgatgacaa tttatttgaa cttttgaatc ggtctgaaca
     4441 atctatcaat aactttttct ttatcacata tcaggctgat gaattacatc acttgacgaa
     4501 tattcaagtt atcatgcctg attcaagaac tgggaaattg attgaaattc aaaatttatc
     4561 aacatttatt tctacaagta atgtcgattt taacgatgaa aaatatcaag agttacaagg
     4621 cttatcagag attgatgatg tagctgattt tgagattata ccacgtcttg cttcagaaaa
     4681 agaagcttag aaaggcaaaa aaatgttcaa tggttcaaga ctggaagaat tacgacttct
     4741 gaatggcctt acacgtgcag atttggcaag agagcttgaa gtgaccgaac aggctatatg
     4801 gcaatttgaa actggagtta cacttccaaa aatgaaaaat aagatagcaa tggctcgttt
     4861 ttttcaggtt gaagttgact attttgatgc tgttgataag aatggttcat tctcactaag
     4921 tcgcattgcc tttcggaatg cagaccttga ggcaaaaaaa aacatccata tccaaatggt
     4981 atatttggaa aaaatgaatc aaatgataga ttatttggag aactttgtat ccattcctaa
     5041 tcaaataatt taccagttag ttgatagtat tgagcaaaaa cttcagcaac atgaatcact
     5101 tgagtttatt gctgatcatg ttagagaggt attggcagta tcagttgata atgccaatct
     5161 cctctatagt ttagaaaaat ctgggatata catttcagag agattaatca atggaaatgc
     5221 ggatgcctat agtgcttggt cacgtaatgg tcgacctttt atcgttttgg gactgggaaa
     5281 atcagcggta cgacataatt ttgatttagc acatgaacta gggcatctac tcttgcacaa
     5341 ccaagtagat tttgaggaac tgtcaaaaga agaattagag gaaaaagaga aagaagccaa
     5401 tcaattcgcc tcctatttcc tgttacctag gaaacaattt ttaatggatt ttgtgaatat
     5461 tgtaggtaag cgtgtcagca atcctgatca atatatcttg ttaaaaaaac gttttggtgt
     5521 ctcaattcaa gcgcttgaat atagagccta caagcttggc ttactgactc cacagcaaaa
     5581 ttcttatttc tatcggcaga tttcaaaaaa aggatataaa gcagttgagc cactagattt
     5641 ggaaattccc ttaaagaaac caagtaaaat cagaagtatc ttagatgtca tcctttcaaa
     5701 caatctttta actctgtcag atattgaacg aaatcagagg gtgtcaaaga attttatcag
     5761 tcaattattt tcatttgatg tgaaattttt tgataagtat ttgcttcaat tagatacgtt
     5821 tgataatgta attccattgt tttctagaaa acaatgatgg ggagtagagt aatgaacaaa
     5881 atcaattctt acaaaatcca cctcccctct ctcctccctt tcggtttcct tttcgccaac
     5941 aattgttaca cctaccgaga ggtgtttatg gaggggcagt ttgaggcggt ggtggaggtt
     6001 gatgaggctg gtcagctgtc gtcctatgtt tgggattgtg agatggagga ggtctatacc
     6061 gcccatctgg tgactgcgcc atctggggct tttgtggggc aggtgagaga aagctatcag
     6121 tccattttgg atcgagtaga ggaggcctgc tgtatcgctc taccatttac caaagaccaa
     6181 agcaaccgca tagcccagct cattaaggag cagtggggcg accttcctga ctatcccttt
     6241 gccaagttgc cgacctatgg ggcttttcgc caccccaaca ataacaagtg gtacgccctg
     6301 gtcagtcaga ttccgaggga caagctggat gggagcggtt ctcaagaaga ggtggagatt
     6361 gtcaatctca aggttgccgg tcgggaaata gcagagctgt tgagtcggtc gggcatcttc
     6421 cctgcctacc atatgtcgaa gaagacctgg gtgtcagtct tgctggatga tacggtggag
     6481 gatcagacgg tgtttgctct ccttgagaag agccgttatc tggtaggacc aaaatcctac
     6541 aaggcgacgc aagggcctga ttactgggtt attccagcca atcccaaggt ctatgatatc
     6601 gataccgaat ttgcagaaaa taaggtagtc tattggccac aaaaatcaac cattcaagtc
     6661 ggggacatcg ttgccattta tgtcacggca cctgtacagg ctattcgcta tgtttgtcga
     6721 gtcttggggg aaaacttgga aaatcatgga gagtcagata ttccaacaga aaagaaactc
     6781 atgcaggtgg aattgcttgc tcagttttcc gatgatgttt tgccgagagc gcgcatgatg
     6841 gacctaggag tgaaagctgt ccgtggacct agacgcctca caaaggagtt gatagacgtt
     6901 ctgacatcag aagtgataaa tatttattaa attatcagaa tatttaataa aaatctttac
     6961 atctgcaaaa aaagcggtat aataagacta ttaaaattta aggaggagta ggtatgaaga
     7021 aaagcttcat tcatcagcaa gaggagattt cttttgtcaa aaatacattt acccagtatt
     7081 taaaagataa gctagaaatc gtagaagtgc aaggaccgat cttgagtcgt gtcggggatg
     7141 gtatgcagga taatttgtcc ggtgtggaga atgcagttac cgttaatgtg aagctgatac
     7201 cagatgctac ttatgaagtg gttcattcgc ttgcaaaatg gaagcgtcat accttggctc
     7261 gctttggatt tcacgaagga gaaggtcttt ttgtacatat gaaagccttg cgtccagatg
     7321 aggattcctt ggatccgatt cactcggtgt atgtggatca gtgggactgg gaaaaggtca
     7381 tccctgatgg tcgtcggaat ttagcttact tgaaagaaac agtagagcag atttacaagg
     7441 ctatccgtct gaccgaattg gccgttgaag ctcgttatga cattgagtct gttttaccaa
     7501 agaaaatcac ctttattcac acagaggact tggtgaagaa cttcccagac ttgacaccaa
     7561 aagagcgtga aaatgtggtt gccaaagaat acggtgcggt tttcctaatc ggtattggtg
     7621 gagaactggc agatgggaaa ccacatgatg gacgtgcacc agactatgat gactggacaa
     7681 gcccatcaga agcaggctac aaaggactca atggagacat cttggtttgg aacgaagcac
     7741 ttggatcagc ctttgagttg tcctcaatgg ggattcgtgt ggatgaagaa gcgctgaagc
     7801 gccaggttgc tattacaggt gacgaggacc gtttggaatt tgattggcat cgtgctcttt
     7861 tgaatggtct cttcccgctt tcaatcggtg gcggtatcgg tcaatcccgt ctggccatgt
     7921 tcttgcttcg taagaaacat attggtgaag tgcagtcgag tgtttggcca caagaagtgc
     7981 gcgataattt tgagaatatt ttataagaga ttggcttcaa tctcttttct tctgctttca
     8041 atctgctatc tgaaaacatt tacaacaaga ttatctgtga tttttgcgcc aatctatgat
     8101 atactttttt agttaaatta aaatatatag aggatattat gacaaaactt agagaagaca
     8161 tccgtaacgt tgccattatt gcccacgttg accacggaaa aacaaccctc gttgatgaat
     8221 tattgaaaca atcccaaaca cttgatgaac gtacgcagtt ggatgagcgt gccatggact
     8281 caaatgacat tgaaaaagag cgtggaatca ctatccttgc taaaaacact gccgtagctt
     8341 ataacggtac tcgtatcaac atcatggaca caccaggaca cgcggacttc ggtggtgagg
     8401 ttgagcgtat catgaaaatg gttgatggtg ttgtgcttgt cgtggatgct tacgaaggaa
     8461 ctatgccaca gactcgtttc gtattgaaaa aagcccttga gcaaaacttg actccaatcg
     8521 tcgttgtcaa caagattgac aagccatctg ctcgtccaga agaagtagtg gatgaagtgc
     8581 ttgagctctt catcgaattg ggtgcagatg atgaccagtt ggaattccct gttgtttacg
     8641 cgtcagctat caacggtact tcatctttgt ctgacaatcc agcagaccaa gaagaaacaa
     8701 tggcaccaat tttcgatacc atcatcgagc atatccctgc accagtggat aactcagatg
     8761 agcctttgca gttccaagta tcgcttttgg actacaatga cttcgtaggt cgtatcggta
     8821 tcggtcgtgt cttccgtggt actgttaaag ttggtgacca agttaccctt tctaaactag
     8881 atggcacaac gaaaaatttc cgcgttacaa aactctttgg tttcttcggt cttgagcgta
     8941 aagaaatcca agaagcaaaa gctggtgatt tgattgctgt ttctggtatg gaagacatct
     9001 tcgttggtga aactgtgact ccgacagatg cagttgaggc acttccagtt cttcgtatcg
     9061 atgagccaac tcttcaaatg actttcttgg tgaacaactc accgtttgca ggtcgtgaag
     9121 gtaaatgggt gacatctcgc aagattgaag agcgcctttt ggccgagttg caaacagacg
     9181 tttctctccg tgttgaccct actgactctc cagataaatg gactgtttca ggtcgtggtg
     9241 aattgcactt gtctatcttg attgaaacca tgcgtcgtga aggctatgag cttcaagtat
     9301 cacgtccaga agttatcatc aaggaaattg acggcgtgaa aatggagcca ttcgagcgcg
     9361 tgcaaatcga tactccagaa gaataccaag gttctgttat ccaatcccta tctgagcgta
     9421 agggtgatat gttggatatg gttgcgacag gtaatggtca aactcgtctt gttttccttg
     9481 tgcctgcgcg tggtttgatt ggttattcaa cagaattcct ttcaatgact cgtggttacg
     9541 gtatcatgaa ccatactttc gaccaatact tgccagttgt tcaaggtgag atcggtggtc
     9601 gtcaccgtgg tgcccttgtt tctatcgacc aaggtaaggc aacgacatac tctatcatgc
     9661 gtattgaaga gcgtggtacc atctttgtaa acccaggtac tgaagtgtac gaaggaatga
     9721 ttatcggtga aaactcgcgt gaaaatgact tgacagttaa catcacaact gcaaaacaaa
     9781 tgaccaacgt tcgttcagct accaaagacc aaacgtctgt aattaagaca ccacgtatct
     9841 tgactcttga agaatcacta gaattcttga acgatgatga atacatggaa gtaacgccag
     9901 aatctatccg tcttcgtaag caaatcttga acaaggcaga gcgtgataag gctgcgaaga
     9961 agaaaaaatt agcgactgag gaataatttc taggagaaga agcatgtttt atttaatcct
    10021 cgccatcatg ttagtacttt tttatatttt tattgcacct agcaatatta aggggactat
    10081 gaatttgatt gcggcagtat ttttactggt agcattagcg attgccttgg tacttggatt
    10141 tttaagaatc atgcaatttc caaaggaaat ttgggttggt ctactaatga ttctgattgg
    10201 tttttgggcg atgcgggata tttatcaatt aaatgacgat acaaaatttt agcagagtct
    10261 ttgatttttg aataccgtaa tacgatatta ctaaggaatt ttatccagct ttttggacag
    10321 tagtggcaat ctattagcta aagaaattat attctgtgat acatcttgaa gaagctctcg
    10381 ttatttataa taaatgacaa gcgcattttc aaggtgtttt tatgtagata aattttaata
    10441 ctcaatgaaa tccccaaaat agcaagtttt tagtacagtc atttaaatta actctgatac
    10501 atcgccgctt tcagcttgcc gcactctacg aaagtgactc gtttcgcatg tcttatttcc
    10561 aacctagaac agcctctagg ctgttctagc tacctgcaca tcggttcctt gtctgaaagc
    10621 taattcatta gaccatacaa ggcaatgagc tgccgccgcc aacttttatc aacatcttag
    10681 caatttgcgt tttacagtct gaagctgatc tctataattg acgggagtgg gaaagacatc
    10741 catacattaa agtaattaaa gacaaattaa ataactatat tagtcattca aacctaaatg
    10801 agagggaatt gttttataaa atattgctaa cagttttccc ttagacaaac tcatattact
    10861 agacaataaa tggaaactat agtaaaatac caagtattgt tattaagttg tactttaact
    10921 tagttgtata atattttggt aaaagagagg aaacgcagat ggatgtaaaa aatcttcgga
    10981 aattaaagcg aattgagtta tatgagatta tgttggctca aagtgaagag attgattgct
    11041 tgagaaatca acttgagaag attaaaacag agttggctga tagaagaatt atgattagtc
    11101 aatctggctc catagcggaa gcttcaatga aactgactaa tatttttgaa gaagcgcaaa
    11161 aagctgcgga tctatatctc tataatgtga aaaacaaaat tggtgatgtt catgaatagt
    11221 tcaaatctca agggaaagga acttccaaaa acttcagaat taaaagagct atatcagcat
    11281 gaaagatata gacatacatt ttggaggaca gtgaaaagta cagtgtttat gttggtagta
    11341 gttgcagcat ttgcaatact aatcgctgta ttatttttgc ctattttgag aatatacgga
    11401 gattcaatga aaggaaccct gaatagtggg gacatcgttg tatcagtaaa gagcaatgat
    11461 tttgaaagca gtgatgttgt tgctttttat tacaataaca atattctggt caagcgcgtc
    11521 atcgctgaag ctggggattg ggtggatatg gataaacaag gaaatgttta tgtcaataat
    11581 caaagattgg acgagccata tttggcaaat agggattatg gtcatacaga tattgagttt
    11641 ccctatcagg taccggaaaa tcgaatcttt gtcatgggag ataaccggaa agagtccatt
    11701 gattcgcgaa acaacgctat tggtacagtc tctaatgaac agattgttgg aaagttggta
    11761 tttaagattt ggccactgtc tgaattggga tggattgaat aaatgaaagt gaaaaaatag
    11821 aaaggaggat cttgtgagag actggttaaa tttagaaaaa atccaaggtt ggcgacgaaa
    11881 gtacaagaag ctcgtgaata tcattgcttt cctcgtagta tttgcaacga cctatgcttt
    11941 gattctaccc gctatcacat tagaccaaga aaaggctgaa taaactgctg ggattgaagt
    12001 gcaagaaaca ccagtaacaa cggaaattag taaattaaca gaaccgatgg tgacaactca
    12061 gcaaactccg atagtgggta gctctgctga tgaagttcaa tctcctgcga cagaaacggt
    12121 tcctgaccct gctgagcaag tgtcaacaga gtctgctagc aaaccccaga ccgaccaaga
    12181 acggattact gagccaacta ccatagttca caaaacgaat gattatgagg tgactgcaac
    12241 atttgatgcg agtgctcaat ttcccaaaga tgttgagttt aatgttagag aactagatag
    12301 ccaatcagaa gaatatcgga cacattatga aaaaaccaag gagaagcttg gagtaaaaaa
    12361 acttgtatat gcccgattct ttgatattca tttttcatca cagggccaag aggtcgagcc
    12421 tgcctcccct gtgaagatta cgattagaaa caaggaatta gttcaacggc cagatgatag
    12481 taaactgaaa attgtccact ttgaagagaa tagccagata gaagttttag aggccgaaac
    12541 gaaggaaaat gaacaacaaa tctccgagat cagttttgac gctagccatt tttctgttta
    12601 tggagatgtt ttagcaaact attatactgt caaatttacc tacactgaca cagcaggtca
    12661 agaacaagtc attacgagtt tgattgataa gactgtgggg acttcacttg gtagtttgcc
    12721 tgaagctcct tttaaaaacg gttatgtatt ttctcattgg attaataaag atactggtga
    12781 tcggattgat gaaaatacgg tgataactgg cgacctgact gctgtagcag tatttaataa
    12841 tatcaatatc tacaccattg atgtcacgta tttctaccac aatgtttcta aaaaccaaga
    12901 tattacgatt gataaggaaa cggtgcaact ggaagcaagt gatgctccat atcaactgac
    12961 accacctgct tctactgagg tgagcaacaa agaggataca actttaccag cagatgctat
    13021 ttactaccct gaaaaaccac ttcttgagtt tacagcagat caactagagc gactggacgt
    13081 agcagatgga gtggatgata attatattag cgaaagagta caatatgttc cttacaatgc
    13141 agagtatgat gtcatttata ggctaaagaa tttgacgggg tcaggttatt ctgatatcca
    13201 gactgttcat gtccgtgggg tactgggttc aactgttaca ccgcaaattc taacctacaa
    13261 ctatgctgac tttgaacgtg ctgatacagc aaagattgag aatactagcg gccaaaaatt
    13321 gtatgtttat tatacacgga aaacctttac tctttcttat aattccaatg gcggtagtaa
    13381 tattccccaa caacagggtc tatacgatag ccagattaag atttctacaa ctactccaac
    13441 aaaagagggg tatacatttg aaggttggta tgataatcct ggactgactg gaaacaagat
    13501 tacaggctct ctcaccttaa agaaagatac aactttgtat gcgaaatgga caccgaacag
    13561 ggttcgctac atcattgggt attacaagga agtctatgac aacaacactg gaacaacctc
    13621 ctatgtatat gatagttcgg cagctggttg gggtctggtt gggactactg taaaaggaac
    13681 agattcaaat attggacctc ctccgccaac ccaaacaacc attggcagca ttggctacga
    13741 gaaggatgtt actaaaagtg ctgcttcaag tattgaaatt gcagctgatg gaacatctgt
    13801 tttgaaagtt tactataaac tgaagcgcta cacttttgaa tttttcttaa atgataacaa
    13861 tgccaatatc accataaatg gtaagaccta ctctgatagg aataggtaca tgatacgtga
    13921 tgttgtgctt ggtcaagatg tctcaaagtt atggccagct tctataacaa atcctaaaga
    13981 agtatacgat gataaagtct actatgatag ctatggtagg ccgataagat acttttttga
    14041 ctactggatt tttgggaatc tactcttcaa aacagatcgg ttcgaagttg ttgagtctat
    14101 gttgccaacg agtggaacaa ccagtaagtt cacagcatat tggaataccc aaggtacaca
    14161 ggctaacgtt gaatattggt tacaacaacc ggatggttct tataagaagt ctgatatata
    14221 tagtcaatct ttcctaaaga ctgcaggact gctaccgaaa gaaatttttg gatattctta
    14281 ttatacagat gctagtttta ctgaagcagg cattaggtat tacggaactc aaggaaatac
    14341 atatcgtttc tactataaac gccaagcctt caaaattgac tattattaca atagtactgg
    14401 gttagattca aagagtaaca ttctctttga gagtaacatc aatacagcaa cttataatta
    14461 ccaaccacca cgttctactg gagttgatgc tgattataca tggggtggat ggtatacaga
    14521 ttcgttattg acagagaagt ataactttaa taagatgcct gccaataact tggttctcta
    14581 tgctaagtgg attgctccaa aatttaaggt tacttttgat atcaacggtg gtaatggaac
    14641 tgcccctgtc gatcaaagtg ttgaaaaata caaatacgct aaggcccctg ctgatccaac
    14701 gagggaacat tacaatttcc ttggttggtc tacagaagat gggaaactct atagttggag
    14761 cgaccaagta accaaggatg tcaaattgac tgcgaagtgg gaattgaaac cattaactta
    14821 tactgttcgc tatcttgaag caggtacaaa tacgcaattg gctgctgata aagtgattac
    14881 gagtccagcg cttgtattga atcaagctat cacagaaaag gcattgggaa ttacaggtta
    14941 tcgaccagat aagagtagtc aaacaattaa cctgaatttt agagggaacg aaataacttt
    15001 ctactataca ccgaaggtaa aagatgttgt ttacaccatc aagtatgtct tgaaggataa
    15061 cccagctatt gaggtagcac ctacagttac tcgtaaggtt gatggaagta tcatccgtgc
    15121 gaaagaagct gctgcagatg tgaataaaca gcatttgcag agtcagtctg gtgttactgc
    15181 tgaaatgctg gaaatggatt actatccaac tgtaaatact caaagtttga ttctaacttc
    15241 tagtgatgca aataatgtga ttgtttttga atatgtcgga ttcgatactc aaacctttac
    15301 ggtaaattat ttggatatgg atggtaagaa aatcgatggt caagaaccat tggtagttta
    15361 ccgaaagaaa ccaggtagtt tcgtggtaga tcataagact ataaatggtt atacctatga
    15421 tcattcgtta gacagtgaga atgcagctga taagacagta taccgtgtaa gtaagggtgg
    15481 tcacataacc attgatctct attataagaa aaacctaaca ctgaccgcat tagataagtc
    15541 caaagtttat gatggcactg ccctatcaag ttcgggtctg tctgatttaa atccttcgta
    15601 cagttcagaa ctgaaaacag gtgacaaatt ggttgccatc agctatgatg gaagtcaaac
    15661 aaatgctggt agtagcgcaa cgacacctaa acttgctaac atcagcaatg catctggtgc
    15721 tgaccggacg aatttctatc acataaccta tcaaccgggt aacttaagag ttgaccaaca
    15781 gccagttgtg gttgtcatcg acggtgaaaa gaaatcgaaa atctatgatg gcaaagcaga
    15841 agcagttggt tataaggtga cggaaataag agattcaagc ggtctctata aaaaaacaga
    15901 tatcaaattt aatggttcaa gttcagagca gtcggttaag aaaaaagatg caggaattta
    15961 tccactcctt ttaagtaata gattctcaaa taccaatcag aatttccaag tagatttctt
    16021 gatttctgat ggggaattaa gaatagatag acggcaactg accataacat ctgactccgc
    16081 tagcaaggct tatgacggta gcgagcttcg tgctgacaat atcacagtct ctgtacctgc
    16141 tggtgttgac tacacaggtt ttgtcgatgg cgaagggatt ataccaacct tcttaggcgg
    16201 tccaatcgat tctggaatga tgccaaactt ctttgaatat gctctaaaat ctggcacgaa
    16261 tttagctaat tatgagttag atatccagtt tggccagctc aaggtcaaag aagtcatcaa
    16321 gattcagaaa acagacctgg cctggcaggc cctttcaggt ggtaagtttg aattgaccaa
    16381 gtgggatggt ttgaactggg ctcaggtaga tggggtgcag gaatttgcca ttaccagcaa
    16441 agatggtatt cggataccgg taggcttaga agcaggtcgc taccgtctgc aagaattggc
    16501 agcacctgat ggttttatcg tcttggatag ctatatctac ttcagcatca aggaaatctt
    16561 taacgaagat aagacatctt ccttctacac agtttccttg tctgatgaag caggcaagga
    16621 tgctagtccg gaacgagcaa cgcttaccaa ggttagtggt gatgccagtc atcgcatcca
    16681 agtggccaat gagcagggca gagccttgcc aagcacaggc ggagatggac agaagtggtt
    16741 tattctttct ggccttgtcc tcatagccat ctcctatctg atgcatctgt ttgttcaacg
    16801 tcgaaggtaa aggagacagt aacaatctcc aaatccctta gtagtaaatc gtctcagctt
    16861 tctaagtaac gtccagtttc ttagacctaa tccaaataaa taaaagaagg aatattatga
    16921 aaaaattaca acaattcttt acatcccttg tggcagtact gacagtcttc gcttttggtt
    16981 ccacggcctt ggcgcaaact gttgatagcg gaaaaagtgg agcaggcact attactgtct
    17041 ctaacgcttc acaaggtcaa acttacactg cctataaact ctttgatgca actgtaacca
    17101 cagatggttc tggtatctca tacaaacttc ctgctggtaa aattgcaacg aactttggtg
    17161 gtgatacttg gttcgaagtg gacagcaaag gtaatattac tgcaaaggaa ggtgctactg
    17221 tctcttcaga agcatttgcg gcttgggcaa agaatttcgg tacagaagtt acaagtgcta
    17281 cagcgaatga taactctctt gtgtttacac atttgacatt tggttactat tttgtaacat
    17341 catcacttgg tgcagtgctt acagtagata gtacaacacc aaatgcaact gttatcgata
    17401 aaaacactac taatccaacc attccagatt caaataatgg tggcggtaag aaaattctta
    17461 gcaatggtgc tacaactagt gaaacaactg caaaaattgg cgataccatc aacttccaaa
    17521 tcaagtttaa tgctaccaac tacgttacta aagatagaca aaccaagcag attgtttctt
    17581 acactatcga agatagccca acagccctcg caattgatca aaattctgtc aacgttaaag
    17641 tggatggtgt ggatatcaca gcaaaaattt cgaagacttt tgatgcaaca ggcaaaatga
    17701 atcttgtcat tacatgggcg gatgcggcag ctagtaataa aaccatctat aactctccag
    17761 ctgaagttat tatcacctac tcagcagtgg tgactaaaga tgccaaggag ggagaagcaa
    17821 ccaactcagc gactattggt tacaacacaa ttgataatcc aacaactcct ccaacaccag
    17881 ttgatccaga caagccaact gaaacaacaa aagtgactac tcaccgtttc actttgaaaa
    17941 aaacaaacaa tgtaggtgaa actttgacag gtgcagagtt caaactctat gatgcagcca
    18001 acaatggaac tgaaatcaag gttgtcaagg aatctgacgg agtgtatcgt gttgcgcagg
    18061 ctgatgagca aggtgttgtc atcgaagctg gcgaagttgt gattaaaggt ctgaaacata
    18121 gcacgaccta ttatcttgaa gaaatgaaag caccgaatgg ttacaatatc ttgacagaac
    18181 gtcaatccat tgaagtgaaa gagaataaca cagcacaagc aaatatcgtc aataaaaagg
    18241 gtggtgtctt gccaagcact ggtgcgattg gaacaacttt attctatcta gttggttcaa
    18301 tcctactttt ggtagcattg gtttatacta tttcaaaacg tcgtatgaac aatatctaat
    18361 tgtccataca atacctaata tttagaatct atcttcggaa gtgcaaaagc aagagtggaa
    18421 gtatttccga agatatttct ttggtcttaa cacaaggaaa ggaggggatt tcatgatcaa
    18481 atggctcaaa aagaaaggtc cgtcttttat catgccatta atttttatat tggggattgg
    18541 actattggct tatccatcgg tcagtgatta ctggaattcc ttccaccaat cagaggccat
    18601 catgtcctat tctgacacag tatcagatat gacagctgac caatacaaag aaatcattga
    18661 tagtgcgcgc cagtataatc aagaaaaacc cttaaactgg aatgtgactg catccgacat
    18721 tgaagcctac aatcaggaat tgaatttcaa taaagatggc atcatgggct atattgagat
    18781 tcctaaaatt gatgtcaagt tatctatatt tcatgggaca gacgaaacgg ttttagagac
    18841 ttctattgga catctagaag gaacatcgtt gcctgtagga ggtttgggaa ctcatagtgt
    18901 actttcaggg catcgtgggc tcccatctgc ccgtctgttt tctgatttag ataagttgag
    18961 agaaggcgat atatttacca ttcacgttct caatgaaaca ctaacttaca aagtggacca
    19021 gattcgagtg gttgagccgt cagatttatc ggctcttacc atggaacctc agaaagactt
    19081 attgactttg gtaacctgta caccctacgg tattaataca cataggctat tagttcgtgg
    19141 ctatcgtatt gaaaatgtta atggtagtgc tttggttacc tctgatgcta tccaaattaa
    19201 agcaattttt attgctccat ttatcgcaac tccaattcta tttgtaatct taatttatat
    19261 ttttataaca actagtaaaa catttcgttc tcggaatagg aatcaagtgt tggatgattt
    19321 tttagttccc aagaaatttt gaactattga aaatgtttca aagtcgattt gactctggaa
    19381 catttttcta ttatagacat tagacaatat ggctgaatga ggtaattgtt caacttctaa
    19441 cctcctgtca actcaaatca attgcctaga ccgacgattg aaacgacttc tttctagtaa
    19501 ctgaccgcaa gggaagaggt ggcagatggt gtagaaatgg cgctgtgatg tcatacctag
    19561 ttcagcttgt aacaaaagta agacaaggat tgattcatct gaaactttaa ctaagccaac
    19621 atttcgccga tatttgaagg aatccgggca atagttgttg tagaagtgat gacaaatttg
    19681 tgataattgg cgtacattcc attgcaaatg atgagattta gcagtatact gtaagtagct
    19741 catttggact acccctctgt atgtttcgtc gcttacagta tagtccattt gggcttttta
    19801 ttgtattttg aaatgaacta gcgctacggg cagagtttac ttttctgtcc tctggcttga
    19861 aaaaggtctt cgtaaagggt aaaataaggt gttagaaagt aaaggtattt gagatgaaga
    19921 tgattgatat tgtaaaaaat aagaaagtgt tagtgctagg tttagctaaa tcaggggaat
    19981 ctgcagcccg tctactagat aaattgggtg ctatcgtcac tgttaacgat ggaaagcctt
    20041 ttgaagaaaa tccgactgct caatctttgt tggaagatgg tatccgtgtt atttgcggga
    20101 gccatccctt ggaattattg gatgaagatt tcgctttgat ggtaaaaaat ccaggaattc
    20161 gctatgataa tcctatggtt gaaaaagcaa ttggcaaagg aattccagta tggacagagg
    20221 ttgaattggc ctacttggta tcagatgttc caatcgtggg gataacaggt tcgaatggca
    20281 agacaacgac aacgaccatg attgcagaag tcttgaatgc aggaaaaaaa cctgcaaaat
    20341 tatgtggaaa tattggctat ccagcatctt cggtcgctca aactgcgact gcagaggata
    20401 ccttggtgat ggaattatcg tctttccagt taatggggac agaatctttc catccgcata
    20461 tcgccgttgt gaccaacctc attgccagtc atattgatta tcacgggact tttgaagact
    20521 acgtagcagc taaatggatg attcagcgtc agatgacggc tgaggatttt gtggtgatca
    20581 acttcaacca gaaagaggct aaggaattgg ctggacagac caaggcaacg gttgttccat
    20641 tttcaacaca ggaagtagtt gatggagctt atttggcaga tggaaaactc tatttcaagg
    20701 gtgaatacat catggatgct gaccaaattg gtgttccagg ttcacacaat gttgaaaatg
    20761 ccttggcaac aattgtggtt gcaaaattgt tgggagtaga tcagcaagcg attcaggaaa
    20821 gtttgtctgc ctttggaggt gtcaaacacc gcttgcaatt tgtaggtgaa atcaacgggg
    20881 tttccttcta caatgatagt aagtctacca atatcttggc gactcaaaaa gctctttcag
    20941 ggtttgacaa tagcaaggtc attttgattg cagggggctt ggaccgtggc aatgaatttg
    21001 atgaattagt acctgatttg gtcggactaa agaaaatggt gatccttggt caatcagctc
    21061 cccgtgttca acgtgctgca gataaggcag aagtggaaac gatagaagct ctcgatattg
    21121 cggatgcgac tagaaaagcc tttgccattg cggaaaaagg agatattgtc cttttaagtc
    21181 cagccaatgc aagctgggat atgtatgcca attttgaagt gcgtggcgac gtcttcttac
    21241 agacctttga ggagttgaaa taatcatgaa aaaaattgtt tttacaggcg gagggactgt
    21301 tgggcacgtg acgctcaatc tccttttgat tccgcgattt ttggaagaag gctgggaagt
    21361 ccactatatt ggtgatggga acggtattga gcatgagcag gttgtgaaat caggtttaga
    21421 tgttcatttc cattcgattg cgaccgggaa attgcgccgt tatttctctt ttcaaaatat
    21481 gttggacgtg tttaaagttg gttttggtgt tcttcaatcc ttgaccatta ttgctaaaat
    21541 tcgtccgcaa gctctttttt caaaaggtgg gtttgtatcg gttccgccag ttattgctgc
    21601 taatttgctg cgggttccgg tctttatcca tgaatcagac ttaacaatgg gactggccaa
    21661 taaaatagcc tataaatttg cgactaccat gtatagtact tttgagcaac ctgccagctt
    21721 gactaaagta aaacatgttg gtgcggttac aaaagtgggg caaacgaatg acaaagttac
    21781 accaattcag ttgccagaaa ttctcagtca cttcgataaa agtctgccga ccctactgtt
    21841 tgtaggtggt tcgggcggtg ctaaggtctt taatgattta atcagtcaga atagtgctgc
    21901 cctgaccgaa cgattcaata ttatcaactt gacgggggac agtagtctca acaaattaga
    21961 taaaaaccta tatagagttg actatgtaac agaactttat caaccgttga tggatttagc
    22021 ggatgtcgtt attacccgtg gtggttccaa tactctgttt gagttgattg ccatgcaaca
    22081 actccatttg attgtgcctc taggacgaca ggccagtcga ggagatcaga ttgaaaatgc
    22141 tctctatgca gagaaaaagg gatattctaa gcagattgat gaaagtcaat tgacatttgc
    22201 cagcctgtta gtagaagtcg atgagctatt gaaacataag gaattttatg tccaaaacat
    22261 ggcaaattct aatgaaattc agtcagtaga tagtttttac aatttgctta gagaagatat
    22321 gggaaggtag gttctatgac ggaaaaagat tcaaatgtag aagaatcagt gctagaagtg
    22381 gaacaggcat cccaagtaga attggattcc gaacaaattt caccagcaga gaaagaatct
    22441 gtattagccg aagagaaaga attttctacg gatgtagaca tacctgagat gactgctccg
    22501 gatgatgaaa aaagtgcctt tttcgaacaa tggaaagcac gccaccaagc ctaccttgct
    22561 cataaagatg aggcagatat tcaggcagtt gacgagggac agacagaaca ggagatccca
    22621 gaagctaaaa agagtaaaag ggtccttttt cagggaatag aaagaaaaac agagagtctg
    22681 aaatctaaaa aggaaacagg ggaaaaggtt caaactttaa aagttgatat tccttccaaa
    22741 gtagtctgga aagctattcc ggttcttgtg acgagtttgt tactggcagc tctagccttg
    22801 tattttattt ctccaaccag caagaaaaaa caaatagagg ttgtcggaaa tgagcgacta
    22861 actgctgagc aagtagaaaa ttatagcctt atctctccgg atgattacaa tgtgactata
    22921 gctttgcatg cagatgctta cgcaaagaat attaagaaga atagttcgtc cgttgagaca
    22981 gcgacaatca agttccagtt tccagctacc tttaccattc acatcaaaga atacgcaata
    23041 ataggctaca ttcagcaaca aagtcagtgg tatccagtat tgtctagtgg agagattggc
    23101 ggtgaaccga tttcacagga ttccttgcca gaagactata caacaatcaa tttatccgac
    23161 aaggaattaa tcaaggaact ggccattgaa ttgggtaaaa tagatgcagg aattcgttct
    23221 gctattcaga caataaattt aacgccaagt aaagtgaccg cggatttgct gacattcaat
    23281 atgagagatg gaaatactgt attagtcccg ttgagtgaga ttagccagaa ggtgtcctac
    23341 tatacaaaaa tagcagcaga agtgactgtt ccaacaacaa ttgatatgga agttggtatt
    23401 tatagatatg caagctgaaa tagataattt tgtaaagaaa aagtaataaa aaaatccttt
    23461 aaaaacacca taattcgata taatatggta taatgaatga tgactaatta tactattttt
    23521 caaaatggaa gatgatttgt taaagttgga agtaagagag gactgataga atggctagaa
    23581 acggcttttt tacgggatta gatattggta caagctccgt taaagtcttg gttgcagaat
    23641 atattgataa cgaaatgaat gtgattgggg tcagcaatgt aaaaagtgct ggcgtcaaag
    23701 atggaattat tgtaaatatt gaggtggctg ctggagcgat taaaaaagcg atcgagcagg
    23761 cagaagaaaa gtcaggtatc cgcattgaaa aggtaaatgt tggattacct gccaaccttc
    23821 ttcagattga accgactcaa gggatgattc ctgttacaac agattcacaa gaaattacag
    23881 acttggatgt tgagaatgtt gtaaaatcag cattgacaaa gagtatgact ccggaacgcg
    23941 aagtgatttc atttattcca gaagagttca ctgtcgatgg attccaaggc attaaggacc
    24001 ctcgtggaat gatgggaatt cgcttggaaa tgcgtggtat gctgtataca ggcccacgta
    24061 ccattcttca caatcttcgt aaaacggtgg agcgtgcagg tgtccaagtt gaaaatattg
    24121 taatttctcc gttggcacta actcgctctg tattgaatga aggtgaacgt gagtttggtg
    24181 cgactgtcat tgatcttggt ggcggtcaaa cgactgtggc tgttatgcgt ggccaagagt
    24241 tgcaatatac aaacatctac caagaaggtg gagattatat cacaaacgat atttcaaaag
    24301 tattgacaac ttcaaagagt attgctgaaa acttgaaata caactacggc attgcctatc
    24361 cgcaagatgc aagtgataag gaaaaattta ctgtcgaagt gattggagaa aacgctccag
    24421 ttgaagtgac cgagcgctac ctttcagaag tgattgcggc acgtctgcgt cagatttttg
    24481 accgtgtgaa acaagatttg gagcgtacac gtgctctaga tttaccagga ggcattgttc
    24541 ttgtaggtgg tggtgctatc ttaccaggaa ttatagaatt ggcccaagaa gtgtttggtg
    24601 ttaacactaa gctttttgtt ccaaatcaaa ttggtatccg caatccagca tttgcaagtg
    24661 tgattagctt tgttgagtat gttggtgagt tagaagatgt agaaaatatt gcccaacatg
    24721 cagtaaatgg tgaaactacc ttgagacata agccagttga aattcctgtt gctcgtcctc
    24781 ggattagtca gccaattcaa agagaaatcg tgaacgaatt gaacacagtt gatcaggtag
    24841 aggaacaagt tgctcctact taccatgatg aggaagaaga agttcgtcca gctgctaagg
    24901 gaaacatcac agatcgcatt cgtggtttat ttggcagcat gtttgaataa gagaaaagaa
    24961 aaggtgattt aaactatggc attttcattt gaagcagcag ctagtcatgg tgctgtcatt
    25021 aaagtaatcg gtgtcggcgg tggtggcggg aacgcaatca accgtatgat tgaagaaggt
    25081 gttgctgggg ttgagtttat tgcagcaaac acagatgtac aagcgctaag tagctctaaa
    25141 gctgaaacag ttatccaact aggtcctaaa ttgactcgtg gtttgggtgc tggaggtcaa
    25201 cctgaggttg gtcgtaaagc tgctgaggaa agcgaagaag cattgactaa tgtattaact
    25261 ggtgcagata tggtcttcat cactgctggt atgggcggtg gctcagggac tggtgcggct
    25321 cctgttattg cacgtattgc taaaaacttg ggtgcgttga ctgtcgcagt tgtgactcgt
    25381 ccgtttggtt ttgaaggaaa taaacgtgga aactttgcga ttgagggaat tgaaggtctt
    25441 cgcgaacaag tagatacact tttaattatt tcaaacaaca accttcttga aattgttgat
    25501 aagaaaacac cgcttttaga agcactaagc gaagctgata atgttcttcg tcaaggtgtt
    25561 caaggaatta cagacttgat tacaaatcct ggtttgatta acttggactt tgcagatgtg
    25621 aagacagtta tggaaaacaa aggaaacgcc ttgatgggta tcggtatcgg tactggtgag
    25681 gaccgagtga ttgaggcggc tcgtaaagcg atttattctc ctcttcttga aacaacaatt
    25741 gatggtgcag aggatgtcat tgtcaatgtt acaggtggct atgacatgac tctgacagaa
    25801 gcagaagatg cttcagaaat cgttaatcag gctgcgggtc aaggtgttaa catttggttg
    25861 ggtacatcta ttgatgaaac aatgaaagat gagattcgtg tgaccgttgt ggctacgggc
    25921 gttcgtcaag atactgctga taaaccagcc cgccatcgta cggaagctgt ttcaccacgc
    25981 ccttctcacc gctttgatca ttcagtagca tcagcaccaa ctcgtggagc tgcacaacaa
    26041 actgaagcgc cgaaagcttc tgccttcgga gagtgggatt tgcgtcgtga aaacttgatt
    26101 cgtccaactg acacagaacc aacatccact gtttcagtcg aaaaatttac aatggatcaa
    26161 gatgaggatg aattggatac accaccattc ttccgtaatc gctaaactaa aatgaatttt
    26221 caaaagaata aggatgctat cttttcagca gttgcaaaag ctgctgagaa ggcaggtcgt
    26281 ccaagtgaat cagtaaaggt aatagctgtc accaaatatg ttgacagctc tattgctaat
    26341 cagctagtga atactggaat tactcatatt ggagaaaatc gagtcgatca gttcttagaa
    26401 aagtataatg ccctagcaga caaacaattg acatggcatt tgatagggac tttacagaga
    26461 agaaaggtca aggacattat tccatttgtt gattatttcc acgccctaga ctctgtcaaa
    26521 ctagctcagg aaatagataa acgtgcgact aaaatagtca agtgtttcct ccaagtcaac
    26581 gtttccggtg aggagagtaa gcatggcttt gcagtatctg agattgatgc ggcacttgct
    26641 gaaattagtt tattggagaa cattgaactt gttggattga tgacgatggc accgattgat
    26701 gctacagatg atgaattaga cgagatcttt tctaaaatgc aggaaatcca agaagaacta
    26761 gctacaagga acttaccacg tatgcccttt acagagttaa gtatgggaat gagtggggac
    26821 tttgaacgcg ccattgctca cggagctaca tatgtgagaa ttggctcagc attctttgaa
    26881 taatggagag gaggaaaata tggcattaaa agatacattt aagaacttat ttaattactt
    26941 tgaagttgac gaagtcaatg aagttgaaga acaggcagat gcctattcaa tgcctaatga
    27001 tcgtcctaaa atgcgtgttg ccaatactac agttgcacct gtgcgcgaac agcagccaaa
    27061 agtagagacg cgtcgggaag cacgttcaga aagtcaactt caacgcctac atgaaaggca
    27121 gcaagaattg atgactaata ataacgaaaa agagattgtc aaaactacaa ttgatattaa
    27181 gtttccaaaa cgttatgaag atgcaccaga gatggtaaat cttttattag acaatgcgag
    27241 tattctcatt gattttcaat atatgtcgga gcaacaagca agacgttgcc tagactactt
    27301 ggatggtgct cgttcagtat tatctggaaa tttgaaaaag gtctcaaata ccatgtggct
    27361 gttaactcca gtaaatgtca cagtcaatat tgaagaattg cgcaatgctg gtacaactac
    27421 tggtgtggct gattcaaatt ttgaatttga tataaaacgg taacgctatg caaattttga
    27481 tttttttact attaaaaatt gtagaaattt attcttatct cttattggca tacgctttgc
    27541 taagttggtt tcctagccta tacacaagct cgattggtcg tttgattcaa tggctggtag
    27601 caccgatttt aaaacccttt aggcggttaa atctgcagtt tatggggttg gattggaccg
    27661 taatggcagc catgattgcg cttaatatgg gaacacgctt cttggttcaa ttattgctcc
    27721 tgttagcata gttatgaaaa atgacaaaaa cttattgcaa catttttcta gggaagaaag
    27781 agagtttgta gagaaaataa tggatatgtg tcagcaagtt gaagatacgt attcatacag
    27841 attaactcac tttttacatc ctagacaaga tgaaattgta tgcaaaattg ctaactacta
    27901 ccagttacaa acgttttcta gtcgtgacct tgtttcgaca gaacattcgc gggttattat
    27961 tgccccgact tattatgagt tggacatcaa ggactttgag ttaaccgctc ttcatttgtc
    28021 ctatgctaga aaatttcaca ccttatccca ttcacaagtt cttggaactt ttctcaatca
    28081 actagggatt aaaagggagt atttgggtga tattttgatt gatgatgaac gattgattgt
    28141 ctttatcgat cagaaatttg ggcagattgc cttacaatct atcactaaag ttgctcgtgt
    28201 ccctgttaag ggaaaggaag aagaatggac gactgttcga ctaccgattg gacaggaatg
    28261 gcgttcaaag gatgtgttgg tttctagtat gagattggat aaattgattt cggtcgcatt
    28321 taatctttca agggcaactg caaacaagtt gattgaggct ggacatgtga agttggatta
    28381 tgttctgaca gaacaaacca gtaaattagt tgaaataggg caattaatta gtgttaggag
    28441 atatggtaga gttcgcctaa atgaattttt aggtttttct aagcaaggga agataaaatt
    28501 aaagttagac attgttaaaa cttaggagga aagatggcac ttacagcatt agaattaaaa
    28561 gataaaacct ttgctacaaa atttagagga tacgacgcag atgaagttga tgactttttg
    28621 gacattgtaa cacgtgatta tgaggattta attcgtaaaa atcatgacca agagttagaa
    28681 ttgaaaaatt tgcgagaacg tttggcttat tttgatgaga tgaaagaatc attgagtaaa
    28741 tcagttcttt tagctcaaga tacagctgag aaagtaaagg ttgcggctga agatcaagcg
    28801 gcaaatatta ttaaacaagc tgactatgat gcggcaacat tgttacatga agctaaagat
    28861 aaggcaaatg aaattcttcg taatgcgact gacaacgcga aaaaagttgt cattgaaact
    28921 gaagaattaa aaaaccagac acgtattttc catcagcgtc taaaatcaac agtagaaagc
    28981 caattatcac tggttaattc atctgaatgg gaggaaatcc tccgcccaac agcaagttac
    29041 attcaaacaa gtgacgaagc ctttcgtgat gttcttcata aggctttgga tgaagaatta
    29101 cctgttgaag aagaaagttt ggattataca cgtcaattga caccagaaga gattgcagaa
    29161 ttaactcgtc aggcagcagc ttttgagagt ggagaatctg tagtactttc aatagaagaa
    29221 taatagaaat cataagcaaa gacaaggtcg ttagaaatat tttaagcgag taggagatgg
    29281 tggaagccct acaatctctt tctatggatc atcactttgt ttgatctttc ctgaaaatag
    29341 taaggagaga cgtccgttca cgttacgaac atagagggat agaggaaact ctatctaaac
    29401 taaggtggta ccacgaactt tcgtccttat ttggcgggag ttttttattt ttatgatacg
    29461 attagaatta gtaaacaagg ataactttga agtagtgtta caagttcaac ttgcatctga
    29521 ggaccaacgc cgagtggcat cggttgaata ttctttagcc caagcttggt tatataaaga
    29581 ttcggggatg attctaccat atgctgtggt atctggcaga aaagttgttg gttttgcaat
    29641 gttatctatt gaacccaaag ataatagtta ttatttatgg cgcttgttga ttgataagga
    29701 ttttcaaaat cgtggatgcg gaaaagaagc catccagcaa ataattggaa aggcgaaggc
    29761 ggatccgctt tgtcataaaa tttcgataaa ttatgtcatt ggcaatcata aaatgcggta
    29821 cattttagaa aaaattggtt ttcaatccgt tggtttagaa ggccaagaaa tgaaaatgga
    29881 attaattata aaataaagga gttatgatga aactaaaaga aacactcaat ttaggtaaga
    29941 cagcatttcc tatgcgtgca ggcttaccaa cacgtgagcc agaatggcaa aaggcctggg
    30001 atgaagcaaa cttgtatgct cgtcgccaag aactcaatga aggcaaacca gccttccacc
    30061 tccacgatgg ccctccatat gctaacggaa atatccacgt tggacatgct ttaaacaaga
    30121 tttctaaaga tattatcgtt cgctctaagt caatgtctgg tttccgtgct ccatttgtac
    30181 cgggttggga tacacacggc cttcctattg agcaagtctt ggcaaaacaa ggtgtcaaac
    30241 gcaaggaaat ggacttggtt gaataccttg aaatgtgtcg tgactacgct tttagccagg
    30301 ttgacaagca acgtgatgat tttaaacgct tgggtgtttc tgcagactgg gaaaatccat
    30361 atatcacttt gacaaaagac tacgaagcag ctcagatccg tgtcttcggt gctatggcag
    30421 acaagggcta tatctaccgc ggtgctaagc ctgtctactg gtcatggtca tctgaatctg
    30481 cccttgcaga agctgaaatc gaataccatg acattgactc aacatctctg tattatgcca
    30541 ataaggtcaa agatggcaag gggctcttgg atacagacag ctacatcgtt gtctggacaa
    30601 ccactccatt tacagtaacg gcttctcgcg gtttgacaat gggagcagac attgactatg
    30661 tcttggttca acctgctggc tctgaccgta agtatgtctt ggcagaagcc ttggttgata
    30721 gcttggcagc caaattcggt tgggaatcct tcgaagtgat ttcaaaacac aagggtgctg
    30781 aatttgaata tatcgtgacc gaacacccat gggatagaga agtggatgaa ttggtcatct
    30841 tgggtgacca tgttacaacg gactcaggta ctggtatcgt ccatacggct ccaggctttg
    30901 gtgaggatga ctacaatgtc ggtgtcaaat atgacttgga ggttgcggta actgtcaacg
    30961 aacgtggctt gatgaatgaa gctgcgggtc ctgattttga agggcaattc tatgacaagg
    31021 ttgtgccaac ggttaaggaa aaattgggtg acttgcttct tgctagtgaa gtgatcaatc
    31081 actcctaccc atttgactgg agaaccaaga agccaatcat ctggcgtgca gtgccacagt
    31141 ggtttgcctc tgtttctaaa ttccgtcagg aaatcttgga ccaaatcgaa gcaacaactt
    31201 tcaatccatc ttggggtaaa acgcgtcttt acaacatgat ccgtgaccgt ggtgactggg
    31261 ttatctctcg tcagcgtgct tggggtgtgc cgcttccaat cttctatgct gaagatggca
    31321 cagctattat gaccaaggaa gtaacagacc atgtagcagc tctctttgag gaacatggtt
    31381 ctatcatctg gtggaaatct gatgcaaaag atcttttacc agctggtttc actcacccag
    31441 gttcaccaaa tggcgaattt accaaagaaa cagacatcat ggacgtatgg tttgactctg
    31501 gttcatcttg gaatggtgtc atgaatgccc gtgaaaacct tgcctaccca gctgatctct
    31561 accttgaagg ttcagaccaa taccgtggtt ggtttaactc atccttgatt acctctgttg
    31621 ctgtaaatgg tcatgcgcca tataaagcta tcttgtcaca aggttttgtc cttgatggta
    31681 atgggatgaa gatgtctaaa tctctaggca ataccattct accaagtgat gttgagaaac
    31741 aatttggtgc agaaatctta cgtctgtggg tgacatccgt tgatacttca aacgatgtcc
    31801 gtgtgtctat ggatattctt ggacaggttt ctgaaaccta ccgtaaaatc cgtaataccc
    31861 ttcgcttctt gattgccaac acttcggatt tcaatcctgc aagtgatgcg gtggcatacg
    31921 aagagcttcg ttctgttgac cagtatctct tggtgaaatt caataaattg gtagttcaaa
    31981 tccgtgaagc ctacgacaat tatgatttca tgggcatcta caaatctgta gtaaactttg
    32041 taacccttga tttgtcagcc ttctacctcg attttgccaa agatgtcgtc tacattgatg
    32101 gtgctaaatc actttctcgt cgtcagatgc aaactgtctt ctatgacatc ttggtgaaaa
    32161 ttaccaagct cttgacgcca atcttaccac atacggcaga agaaatctgg tcttacttgg
    32221 aacacgaagc agaagaattt gttcagttgg cggaaatgcc agaggtggaa acctttgcta
    32281 atgaagcgca gcttttagct gattgggaaa actttatggt cttccgtact caggcacaaa
    32341 aagccttgga agaagcacgc aatgccaaag tgattggtaa gtcacttgaa gctcatttga
    32401 ctgcctatgt ctcagctgaa accaagtcct tcttggagag cttgaatgca gaccttgctc
    32461 agttgctcat cgtttcaaac ttgacagtaa caactgaaac tgccccatca acagcgcttg
    32521 tggttgatga agttgccttt gctgtagaac gtgcagccgg tgaagtatgt gaccgttgcc
    32581 gccgtattga tactagtgtt gcagagcgca gctatggcgc aacaatctgt gaccactgtg
    32641 caagcgtagt ggaagaaaac tttgctgaag cagtagctca aggttttgaa gcctaagcaa
    32701 tcacaataca tttgttaaag tctatctagc gataggcttt ttttgtaata cttttcgaaa
    32761 atcaaaatta ttcgttgtca agagccttga tgaactccag ttctatcttc ggcttcgttt
    32821 cctaggctac ttttgatttt cattgagtat aaatagaaaa aaagaagcca tctggcttct
    32881 tacagaacgt agacaaactc caaaaatata aaaaattgaa gaggtttgcg aaagatagca
    32941 agtgattaaa ctcttagaaa cattgatatt tcagcgtttc tgagagtttt ttattttcaa
    33001 cataaagaaa aaagattgaa gacaattgtc caaaatggac cttttcttca atctgaaaga
    33061 agccagatgg cttcttacac ttctgcgata atgggaatag acatttcaat caaacggtct
    33121 gtgtgaatcg tttgaatggc agccttgtta atagttcgtt catcaatttt ccgatgaagg
    33181 aagaaatcac gaatttgctc gatttcattt tgttgtactg cacggtattt attactaatc
    33241 aagagttcat aatgacgggg tgcctgtgtg aaaataacgt ctgtattacc tgcagaataa
    33301 gtctctacta ggaaagcatc agtattagcc aactggcttt ggacaagatt gggatgacta
    33361 tttgtcgtgt taatgatttt catgtggaac ctcctctatc tctttggcta cattatagca
    33421 cgattagagt gtttttacta gttattgaat gaattttctt gcaatttcca ttgttcaatg
    33481 ccccatttgt gactaccacg tttgagttta tcgatggctt cattgactgg gaaccaagca
    33541 atatggttga aatcttctag tggttgtcct atttgatggt agctagttac ttcatagatg
    33601 taggctggat tatagaaatg ggtatcgcgg tggctagagt agaagtattc gtcagcctga
    33661 ccaaagtatt ttccgatttc agcggtgaat ccaagctctt ccatcaattc gcgctccaaa
    33721 gcaatgaggt gattttctcc cttttcaatt tctccaccag gaagaaacca agctccgttt
    33781 ggtgcttgaa cgagtatgat ctgttctttc ttttcatctg ggataactgc gtaaacacca
    33841 aagcgactct ggtagctgac gccagccttc ttttctccaa atacagcaat tttctccata
    33901 ggcaattcta tcctctttca ttattggaat gagttgtata cattatacca cttttttatt
    33961 atttttcctt gtgataggct ttacaaagta aagttttttt ataggatgga gatggggaag
    34021 aatttagaaa aatagagtag caaaacagta aaataggcta ctcgtagaga gcagctctat
    34081 tttcttattt tgtctttgtt tgtgccttga tttgaattgt acctttactt gacatgacag
    34141 cacgtaggtc tttttctgct ggatgttcta agtagaagtc ggtgatagca tcttcaatct
    34201 gatcttggat ggttctgcgt agtggacgag ctcccatctt tggattgtag ccaaggtcca
    34261 ctaatttctc cttaacttta tctgttacat ggaggctgat gccattgtga gaaaggcgtt
    34321 tgtttacatc gtctagcatg aggctgacga tttcaagtag gttttccttg ctcagtggtt
    34381 ggaactcaat aataccgtca aatcggttca taaattcagg tgtgaagaaa ttgctaagtt
    34441 ggccaaggac tgattgagtc cgcccttcca tagccgcacc aaaaccgaca cttgcttcaa
    34501 cttttccagt accagcattt gatgtcatga tgataatggt atctttgaag ctgactgtcc
    34561 gaccttgtcc atctgtcaga cgcccatcat ctaagacctg aaggaacatg tgcatgacat
    34621 ctgggtgggc tttttcaact tcgtcaagga ggatgagtga gtaaggatta cgacgaactt
    34681 tttcagtcaa ttgtccagcc tcctcatagc ctacatagcc tggaggagct ccgacgagtt
    34741 tagcgacagc gtgtttttcc atgtattcgg acatgtcgaa gcggatcatg ctgtcagccg
    34801 aaccgaagag ttcgatagct aattgcttag acaattcggt tttaccgaca cctgttggtc
    34861 cgacaaagag gaaggaacca atgggacgat ttggagcacc gagaccgaca cgattacggc
    34921 ggatggcttt agctatcttg tcaactgctt catcttgtcc gataacatgg gcttttaagt
    34981 cactagcgag gctcacaagc tgggactgtt ccttttcttt taaatcacca actgggatat
    35041 ttgttttttg ctcaacgatg gcttcaattt ctttttcagt aatgagtgga atatcttctt
    35101 cgctgatagt tgccttttgc atctccttgt acttagcaat ttggtcacgg aaataggctg
    35161 ctttttcata gtcctcatcc cgtgtagctt gtgctttacg attttcggaa tcaatcaggc
    35221 gttggtcaat ttcctttgga tcaataaagt tgagggtcaa attcattttt gaaccagctt
    35281 catccagaag gtcaatagcc ttgtctggta ggaaacggtc ttgaatgtag cgattggaca
    35341 gtactgcggc agcttcgata gcagcatcgg agtatttaac atgatggtaa tcctggtatt
    35401 tattttggat acctttgagg atggtaatgg tttcttcgac acttggttct tcaactttta
    35461 caggttgcat acggcgttct agggcggcat ctttttcgat aatacggtac tcgttgagcg
    35521 ttgttgcacc gactagttgc atttcaccac gtgcgagggc tggtttgagg atattgcctg
    35581 catccatgtt accatcgcct gcagagccag caccgacaat ttcgtgaatc tcgtcaataa
    35641 aaagaatgat ttcgcgacga ttacggattt cttccatgag tttttgcatg cgttcttcaa
    35701 attgtccacg gatacctgtt ccttgtacga ggctgacaac atccagacga atgacttcct
    35761 tgtctcgtaa tttttgtggg acatcgccat cgacaatttt ttgagccaag ccttcaacaa
    35821 ccgctgtttt acctacccca ggctcaccga taagaacagg attgtttttt gtacgacggt
    35881 tgagaatttc gatgacacgg gtaatttctt gatcgcgacc gattactgga tcaatatccc
    35941 cacgacgggt aatttcggta acgttgatac caaattcttc aaggagccca tttggttgtt
    36001 ggggttgttg cggaggaggg gtctgtccac cacgtccatt atgcccaccg gcttgagtgg
    36061 gaggagtctg ttcgcgattt tttccagcag gggtattgcc aggatagcca cctaggtgat
    36121 tgaaaaattc actaaaggga tccatattgt taggatttgt taaatctccc aacccacgta
    36181 ggatagcatt atgagggtct gttttcatga tttggtagca gttgtgacag aggtctacct
    36241 gctgctgttt accgtttaag ttggtgtaga gatggatcgt tgcgtcgttg atattacaat
    36301 ttttgcagag cataattcta cctctttctg tgaaaaaatg tgacctattg ttaaatagtc
    36361 aaaaaaggtc agttctagct ttattataac aagattcata gaaaaatcaa gaaactgcta
    36421 cgcttggaaa aactttctat gaaaaatagg gcgataggaa gaaaataggg aaaaaataag
    36481 acttttttgg taatatgtgg taaaatattc ctataaaaag gattaggaga acgaatatgg
    36541 aatcacattt ggtgagaatt atcaatcgtc tggaggctat ggctaatgac ggcggtacgt
    36601 tgaaacgtaa tttcgaacgt gatggtattg ttgttgcaga agtggcttat agctatgacg
    36661 aggaaaatgg ttcagtattt accttgcgtg atgttgctgc tcgtgaaacg tacgcgtttg
    36721 acagcat
//
LOCUS       DBNFCO010000009        36227 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.009, whole genome shotgun sequence.
ACCESSION   DBNFCO010000009 DBNFCO010000000
VERSION     DBNFCO010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 36227)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36227)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36227
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.009"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            106..177
                     /locus_tag="AC1PIV_000401"
     tRNA            106..177
                     /locus_tag="AC1PIV_000401"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:139..141,aa:Glu,seq:ttc)
     gene            183..255
                     /locus_tag="AC1PIV_000402"
     tRNA            183..255
                     /locus_tag="AC1PIV_000402"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:216..218,aa:Asn,seq:gtt)
     gene            complement(324..2903)
                     /locus_tag="AC1PIV_000403"
     CDS             complement(324..2903)
                     /locus_tag="AC1PIV_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HIP6611453.1"
                     /translation="MKKIFTKTSIYYLLSFLIPLTIISIVLAFQGIWWGSDTTILASD
                     GFHQYVIFNQTLRNTLHGDGSLFYTFSSGLGLNFYALSSYYLGSFLSPIVFFFDLQSM
                     PDAIYLVTIVKFGLTGLSTYFSLKGIHKNLKEEWALLLATSFSLMSFSTSQLEINNWL
                     DVFILLPLVLLGLHRLLKKQGPILYYITLTCLFIQNYYFGYMVAIFLTLWTLVQLSWI
                     DSQRIKRFINFTIVSILSALSSMFMLLPTYLDLKTHGETFTKIVNLKTEDSWYLDFFA
                     KNLVGSFDTTKFGSIPMISVGLVPLILALLFFTLKEIKPTVKLSYALFFTFIISSFYL
                     QPLNLFWQGMHAPNMFLYRYAWALSITVIYLAAETLVRLRQVSIKNFTLIVSFLLICF
                     TSTFIFRDHYEFLTDVNFLLTLEFLIAYFILFVAMIRYKSSLKWINIVLLFFTFLELG
                     LHSHYQVQGISDEWHFPSRSNYEEKLTDIDSIVKSTKTTTDSFYRIERLLPQTGNDSM
                     KFNYNGISQFSSIRNRASSSVLDKLGFRSDGTNLNLRYQNNTIIADSLFGVKYNLATT
                     DPNKFGFTLNQSQSTINLYENSFNLGLALLTEGIYKDVNFTNLTLDNQTNFLNQLTGL
                     SQKYYHTLSDVVSQNTVELSNRMTVNKVDNEDAAKATFLVNIPANSQVYLNLPNLTFS
                     NENQKKVVITVNNQSSEFTLDNAFSFFNVGSFTTDVQVQVNVYFPENNQVSFDKPQFY
                     RLDLLAFQQAISILQEKQVVTKTDGNKVTVDFVTDKESSLLLTLPYDKGWNATIDGKP
                     IKIQKAQDGFMKVDVSPGQTKLVLTFVPNGFYLGLLISFGAVFVFFSYQFIGYYYSKN
                     REY"
     gene            complement(3210..4832)
                     /locus_tag="AC1PIV_000404"
     CDS             complement(3210..4832)
                     /locus_tag="AC1PIV_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HIP6611454.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTAGNTYGLIGANGAGKSTFL
                     KILAGDIEPSTGHISLGPDERLSVLRQNHFDYEDERVIDVVIMGNEQLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNISEDLHYQNMSELTNGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSINWLEDFLIDFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKIFVGNYDFWKQSSELAAKLQADRNAKAEEKIKELQEFVARFSANA
                     SKSKQATSRKKMLDKIELEEIIPSSRKYPFINFKSEREIGNDLLTVENLKVVIDGETI
                     LDNISFILRPGDKTALIGQNDIQTTALIRALMGDIEYEGTVKWGVTTSQSYLPKDNTR
                     DFDTNESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKAFKESIIFASHDHEFIQTLANHIIVI
                     SKNGVIDRIDETYDEFLENAEVQAKVQELWKA"
     gene            complement(4897..5769)
                     /locus_tag="AC1PIV_000405"
     CDS             complement(4897..5769)
                     /locus_tag="AC1PIV_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HIP6611455.1"
                     /translation="MKERIKDFISVTLGSVVMAIGFNSFFLENNIVSGGVGGLAIALN
                     ALLRWSPSDFVLYCNIPLLIICWFFLGKSVFIKTVYGAIIYPLCIKLTAGLPNLTENP
                     LLAAIFGGIILGFGLGLVFLGNSSTGGTGILIQFIHKYTPLSLGLTMAIIDGIIVGLG
                     FVAFDTDTVMYSIIALMTITYIVNRMMSGTQSSRNVMIISQKSEEIKDYITKVADRGV
                     TELPIIGGFTGVDKRMLMTTISIPEMQKLETAVLEIDETAFMVVMPASQVRGRGFSLQ
                     KDHKHYDEDILIPM"
     misc_binding    5871..6077
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            6124..7149
                     /gene="trpS"
                     /locus_tag="AC1PIV_000406"
     CDS             6124..7149
                     /gene="trpS"
                     /locus_tag="AC1PIV_000406"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HIP6611456.1"
                     /translation="MSKPIILTGDRPTGKLHIGHYVGSLKNRVLLQDAGQHELFVFLA
                     DQQALTDHAKEPQKIVESVGNVALDYLAAGLDPAKTTIFIQSQIPELAELTMYYMNLV
                     SVARLERNPTVKTEIAQKGFGEGIPAGFLVYPVSQAADITAFKANFVPVGNDQKPMIE
                     QTREIVRSFNHAYQTDILVEPEGIYPENEAAGRLPGLDGNAKMSKSLGNGIYLADDMD
                     TLKKKVMSMYTDPNHIRVEDPGKIEGNMVFHYLDVFGREEDKAEIEAMKEHYQRGGLG
                     DVKTKRYLLDILERELGPIRERRLEFAQDMGQVYAMLEAGSQRARQVAAKTLDQVKSA
                     MGINYFK"
     gene            7381..8862
                     /gene="guaB"
                     /locus_tag="AC1PIV_000407"
     CDS             7381..8862
                     /gene="guaB"
                     /locus_tag="AC1PIV_000407"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003090086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HIP6611457.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPHDIDLKTQLAPNLTL
                     NLPIISAAMDTVTDSKMAIAMARAGGLGVIHKNMSIAEQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEAEKLMATYRISGVPIVETLENRKLVGIITNRDMRFISDYSQPISTNMT
                     SDELVTAPVGTDLATAEAILHKHRIEKLPLVDENGRLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIKEIRDHFPTR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAGVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGHAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKQGSKDRYFQASVNEANKLVPEGIEGRVAYKGSVADMIFQMVGGLRSGMGY
                     VGAGNLTELHENAQFIEMSGAGLKESHPHDVQITNEAPNYSVQ"
     gene            complement(9134..10228)
                     /gene="recF"
                     /locus_tag="AC1PIV_000408"
     CDS             complement(9134..10228)
                     /gene="recF"
                     /locus_tag="AC1PIV_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638862.1"
                     /note="All proteins in this family for which functions are
                     known are DNA-binding proteins that assist the
                     filamentation of RecA onto DNA for the initiation of
                     recombination or recombinational repair; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HIP6611458.1"
                     /translation="MWLERLELQHFRNYNQLDIEFHKGLNVFLGENAQGKTNILESIY
                     VLALTRSHRTRTDKDLLQFQEKELSISGLLHRTSGKVPLDIHLTDKGRVTKVNHLKQA
                     KLSNYIGHMNVVLFAPEDLQLIKGAPALRRKFIDVELGQIKPLYLSDLSNYNHVLKQR
                     NTYLKSTDKIDENFLSVLDQQLAEYGSRVIQHRIDFLKKLEEFGNRKVQEISGNREEL
                     TIEYQTSIELTDDVNLIDKFLTELEKSRKRDLFKKNTGVGPHRDDVAFFINGMNAHYA
                     SQGQHRSLVLSLKLAEIELMKEVTREYPILLLDDVMSELDNNRQIKLLETITDTIQTF
                     ITTTSLDHLHKLPDSLKIFHIESGKVTESE"
     gene            complement(10231..10614)
                     /gene="yaaA"
                     /locus_tag="AC1PIV_000409"
     CDS             complement(10231..10614)
                     /gene="yaaA"
                     /locus_tag="AC1PIV_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HIP6611459.1"
                     /translation="MEFKLFDDYITLQALLKTTGILHSGGAIKGFLEENTILFNGEDE
                     KRRGKKIRVGDVITLPDHNTSITIVAPSAEEIKQHQEDQAEKERVAAIVKKLNQENKN
                     NKKQVKTPKKATKKTERKPVRFPGM"
     gene            10688..11941
                     /gene="yfmF"
                     /locus_tag="AC1PIV_000410"
     CDS             10688..11941
                     /gene="yfmF"
                     /locus_tag="AC1PIV_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF-P 5-aminopentanol modification-associated
                     protein YfmF"
                     /protein_id="HIP6611460.1"
                     /translation="MKLQEGVDLHFIDTDQFTTNRIRIRFAAEMSEATVAGRVLVANI
                     FEMGNQEFQTAQAVRRRLAELYGAQFSTSVSKRGRVHCVDVTISYVSPRHLPENEDIT
                     VEILDFLYTCIFRPLKKGRGFDSQIFEVEKTNLINFLQSEIEDNFYHVDVEMSKLFYK
                     DPSLQIPRVGRLDLVEKETAESTFQIYRNMLRMDKIDIFVLGKVDREQVKRKLEDFGF
                     TYRNPKLELEYHQEYSNITQEKIERKQARQSILELAYHLQVVYNDVNYPALMVFNGLL
                     GAFSHSKLFMNVREKESLAYTIGSQVSIFSGMLKVYAGISRENRLRVMKLISKQLLDL
                     KCGKFTEEELELTKNMLIHSATLAQDRQNNLIEQVYNQVTLGNRNLSWLDWIEAIKSV
                     SIDDVIQVGQMINLQAVYFMEGTEE"
     gene            11938..13221
                     /gene="yfmH"
                     /locus_tag="AC1PIV_000411"
     CDS             11938..13221
                     /gene="yfmH"
                     /locus_tag="AC1PIV_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002941810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF-P 5-aminopentanol modification-associated
                     protein YfmH"
                     /protein_id="HIP6611461.1"
                     /translation="MKLVEKKYPYMKESVFYGKVDNGLTVILLPKVDFHETYGILTTN
                     FGGIHTRFTLANGNSVVYPAGIAHFLEHKLFETENEEDIMNEFAKLGASANAYTSFRQ
                     TSYLFSTTQKVLESLSLLQSFVREPYFTEDNVEREQGIIEQEIEMYQDDADYRLFTGI
                     LSSLYPESPLAYDIAGTVESIAAITADDLHENFDVFYHPSNMNLFVIGNFDLEAVWKQ
                     ISSYQVAQMDNPAQSFELAGIQKLPIQEHLSEQFEVSTPKLAVGLRGNDEVDKETIQK
                     YRLSLQFLFAMLFGWTSKRYQQLYEQGKIDSSFQFQLEVTPEYHYLIISGDTQEPITL
                     SSILMKALRKFEDDADVTEDHLQLLKNEMYGDFIRSLNSLEFTASHFVSQYSEYENVF
                     DIPQMIQSLQLDDIREAGRRFIDHCDMTDFTIFPK"
     gene            13303..14160
                     /gene="rodZ"
                     /locus_tag="AC1PIV_000412"
     CDS             13303..14160
                     /gene="rodZ"
                     /locus_tag="AC1PIV_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoskeleton protein RodZ"
                     /protein_id="HIP6611462.1"
                     /translation="MRQKSIGEVLRTAREGRGWTFVDLQRITKIQAKYLQALEYNDFD
                     FIANSDVVQSILKAYAEALELDADVLLDAYETNSLVKYYEDGEEELRSSELKRSYKVR
                     KRKKNSYLPLIYLLLATGLIIIFVIYIVHSRLKNRASITPTTTSYSIVEQSVSEASSG
                     TETSSTEQAQSNSTSSSSSATENVTISGSGSNIVATLKTVTYPVEVTVTAKNTTSWIS
                     LSDTLLEGGVTLTPDNPTVTTTIEEGVTSTTLILGVVKGVEVSVGGQKLELSALTADT
                     GSITINFEQ"
     gene            14170..14709
                     /gene="pgsA"
                     /locus_tag="AC1PIV_000413"
     CDS             14170..14709
                     /gene="pgsA"
                     /locus_tag="AC1PIV_000413"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002941818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HIP6611463.1"
                     /translation="MKKENIPNALTIGRILVIPIFILLLTVWNSTISHVLAALIFALA
                     SITDYLDGYLARKWQVVTNFGKFADPMADKILVMTAFIMLVELGFAPAWVVAIIICRE
                     LAVTGLRLLLVENGGTVLAAAMPGKIKTFSQMFAVIFLLLHWNVVGQITLYIALFFTL
                     YSGYDYFKGASFLFKDTFK"
     gene            14706..15542
                     /locus_tag="AC1PIV_000414"
     CDS             14706..15542
                     /locus_tag="AC1PIV_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002941820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HIP6611464.1"
                     /translation="MMNIIEVKNLKYKYNQEDEQYTLNDVSFHVKQGEWLSIIGHNGS
                     GKSTTVRLIDGLLEAESGDIYIDGDALTIDNVWDKRRLIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGIPLEEMRSRVDEALELVGMTDFKTREPARLSGGQKQRVAIAGVVALRPK
                     IIILDEATSMLDPEGRLDLIKIVREIKERHGMTVISITHDLDEVALSDRVIVMKNGQV
                     ESISTPNELFMREDLVDLDLDRPFTTELASSLRQTGLDLPLRYFTEEELEETLWELIS
                     KK"
     gene            15518..16360
                     /locus_tag="AC1PIV_000415"
     CDS             15518..16360
                     /locus_tag="AC1PIV_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002267082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HIP6611465.1"
                     /translation="MGIDLQEVSYTYQAGTPFEGRALFGVDLEIVDGSYTALIGHTGS
                     GKSTILQLLNGLNVPTEGRVVIDDVVITATSENKDIKQVRKKVGLVFQFPESQVFDET
                     VLKDVAFGPQNFGVSQEEAETIAREKLALVGIDESLFERSPFELSGGQMRRVAIAGIL
                     AMEPSILVLDEPTAGLDPAGRQELMDIFKKLHESGMTIVLVTHLMDDVANYADFVYIM
                     EKGKLVRSGKPVDIFQEVDFLESIQLGVPKITKFAANLERRGFVFERLPITIEEFTGM
                     VTHG"
     gene            16353..17147
                     /locus_tag="AC1PIV_000416"
     CDS             16353..17147
                     /locus_tag="AC1PIV_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     component T family protein"
                     /protein_id="HIP6611466.1"
                     /translation="MDKLILGRYIPGDSIIHRLDPRSKLLAMFGFLLMIFWANNLVTN
                     ALLIAFVLGMVVLSRIRLSFFINGLKPMIGIILFTTFFQVFFTPGATILWEFWIFKLS
                     VEGLQQAAIIFVRFVLIIFFSTLLTLTTTPLSLADGIESGLAPLKKFKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQRARGVDFNEGNLIQKVKSVIPILIPLFASSFKRADAL
                     ATAMEARGYQGGDGRTKYRILEWKLADTLAILVMLALAGLLFILKK"
     gene            17279..17833
                     /locus_tag="AC1PIV_000417"
     CDS             17279..17833
                     /locus_tag="AC1PIV_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009911037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HIP6611467.1"
                     /translation="MNITLKKNLKTTIAGLVAGISLLTAGVVSAETYTVKSGDTLSEI
                     AETYNTTVEKLAEQNKITNLDFIHVGQVIELGDVTVKAVESSVEQTQSTSTSTATVTT
                     STYSSNLSAEDAAAKEWIAMKESSGSYDARNGIYIGRYQLTNTYLNGDYSPENQERVA
                     DAYVASRYGSWSAAKAFWLANGWY"
     gene            complement(18290..19162)
                     /gene="sdaAA"
                     /locus_tag="AC1PIV_000418"
     CDS             complement(18290..19162)
                     /gene="sdaAA"
                     /locus_tag="AC1PIV_000418"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HIP6611468.1"
                     /translation="MFYTIEELVQQADNFSGNVAELMIATEIELTGRSREEILTIMSR
                     NLTVMKASIVDGLTESKSVSGLTGGDAAKLDAYMKSGKTLSDSAVLSAARNAMAVNEL
                     NAKMGLVCATPTAGSAGCLPAVLGVAIEKLNLTEEQQLDFLFTAGAFGLVIANNASIS
                     GAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAICFVIKNMLGLICDPVAGLVEVP
                     CVRRNAMGASYAMVAADMALAGIESKIPVDEVINAMYQVGSALPTAFRETAEGGLAAT
                     PTGRRLAQEIFGED"
     gene            complement(19175..19846)
                     /gene="sdaAB"
                     /locus_tag="AC1PIV_000419"
     CDS             complement(19175..19846)
                     /gene="sdaAB"
                     /locus_tag="AC1PIV_000419"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HIP6611469.1"
                     /translation="MTNLKFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFGDEPT
                     EVEFQLYNSFAKTYRGHGTDVALVAGILGMDTDDPRIPDSLDIARERGIKVYWRVNKD
                     SNTPHPNTTRIIIKNDKKSISATGVSIGGGNIQVTELNGFSVNLNMNTPTIIIVHQDV
                     PGMIAKVTDVLSKYDINIAQMNVTREKAGEKAIMIIEVDARQCENSIAEIEKIPHLHN
                     VTFFN"
     gene            20061..21185
                     /gene="mnmA"
                     /locus_tag="AC1PIV_000420"
     CDS             20061..21185
                     /gene="mnmA"
                     /locus_tag="AC1PIV_000420"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002941846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HIP6611470.1"
                     /translation="MSIDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDD
                     TDENGFCTATEDYKDVAAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDV
                     MCNKEIKFKAFLDYAMNLGADYVATGHYAQVTRDEDGTVHMLRGADNGKDQTYFLSQL
                     SQEQLQKTMFPLGHLQKPQVREIAERAGLATAKKKDSTGICFIGEKNFKEFLGQYLPA
                     QPGRMMTVDGRDMGEHTGLMYYTIGQRGGLGIGGQIGGDNEPWFVVGKDLSKNILYVG
                     QGFYHESLMSTSLQASQVHFTRDMPEEFTLECTAKFRYRQPDSQVTVKVKGDKAEVIF
                     AEPQRAITPGQAVVFYDGQECLGGGMIDMAYKDGEACQYI"
     gene            complement(21228..21617)
                     /locus_tag="AC1PIV_000421"
     CDS             complement(21228..21617)
                     /locus_tag="AC1PIV_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000106206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HIP6611471.1"
                     /translation="MSTNLEIFNAYNNALIAGDFAALFETMADDIIWHQPGNHSTSGA
                     KIGKEVLGAHLATFAEKTNGTFKVVTNWVSDNDTLVAANVTFLGTRTDGEELNMNGID
                     LFRMEDGKIKEVWLFSADQKAEDAFWG"
     gene            21743..22069
                     /locus_tag="AC1PIV_000422"
     CDS             21743..22069
                     /locus_tag="AC1PIV_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HIP6611472.1"
                     /translation="MNKVSEYGICPFATTQKVLTGKWGLVIIYQLSTGTKRFNELQRL
                     IPGITQTMLTRHLRQLEEDRIISRTVYAEVPPRVEYSLTEMGEKFRSVLDAVEAWGLE
                     YIETLT"
     gene            22211..22663
                     /locus_tag="AC1PIV_000423"
     CDS             22211..22663
                     /locus_tag="AC1PIV_000423"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016817 - hydrolase activity, acting on
                     acid anhydrides [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0009132 - nucleoside diphosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HIP6611473.1"
                     /translation="MDFRTRVDNQIFGVRATGLVVQDEKLYLVKSPEGKYYTLGGAIQ
                     LGETTEEAVQREMKEEIGIDVEVGPLAFIVENQFTLQEKSYHQIEFLYLVTPLSEPVT
                     YLEEGNSIRQCEWIAFVDLEKLDLNPAFLKTELAKWDGQLKHFMNKDN"
     gene            22680..23111
                     /locus_tag="AC1PIV_000424"
     CDS             22680..23111
                     /locus_tag="AC1PIV_000424"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016817 - hydrolase activity, acting on
                     acid anhydrides [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0009132 - nucleoside diphosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HIP6611474.1"
                     /translation="MPVKLIAHVLLTVADSHLMIQRSQIKRGEPNVFPLHWDIPGGRV
                     EENELPRDAAVRECFEETGISIEKENLTIIHEDSQFDEEKQTVFTRLVYEVTLPEQPK
                     TILLDPEEHTDFLWLAPSDKNKKNLVPYLDEILEKRRINGF"
     gene            23101..23562
                     /locus_tag="AC1PIV_000425"
     CDS             23101..23562
                     /locus_tag="AC1PIV_000425"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016817 - hydrolase activity, acting on
                     acid anhydrides [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0009132 - nucleoside diphosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HIP6611475.1"
                     /translation="MDFRTRIDNQIFGVRATALIIKDGKIFLTKDAKGRYYTIGGAVE
                     VNEVAADAAVREVKEELGIDSRVNQLVFVVENQFTHEGIDFHNIEFHFIVEPIGEMPK
                     EMIEGKLKQPCEWIALDNLVNLDVVPAFLTQELPNWSGQVKHIMNMKERTT"
     gene            23559..25475
                     /gene="mnmG"
                     /locus_tag="AC1PIV_000426"
     CDS             23559..25475
                     /gene="mnmG"
                     /locus_tag="AC1PIV_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HIP6611476.1"
                     /translation="MTHTFAENYDVIVIGAGHAGVEAGLAASRMGCKTLLATINLDMV
                     AFMPCNPSIGGSAKGIVVREIDALGGEMGRNIDKTYIQMKMLNMGKGPAVRALRAQAD
                     KAEYASEMKRTVERQENLTLRQTMIDEILVEDGKVIGVRTATNQKFSAKAVVVTTGTA
                     LRGEIIIGDLKYSSGPNNSLASITLADNLKELGLEIGRFKTGTPPRVNARTINYEDTE
                     IQPGDEKPNHFSFLSKDEDYLLDQIPCWLTYTNATSHEIINSNLHRAPMFSGIVKGIG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTDEIYVQGLSTSLPEDVQQDLIHSIKGL
                     ENAQMMRTGYAIEYDMVMPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIVAGI
                     NAALKVQGKPELILKRSDGYIGVMIDDLVTKGTVEPYRLLTSRAEYRLILRHDNADMR
                     LTEIGRQVGLVDDERWQVFQIHKNQFDNEMKRLESIKLKPIKETNEKVVAMGFKPLTD
                     ALTAKEFMRRPDVTYADAVAFIGPAAEDLDAKTIELIETEVKYEGYIAKALDQVEKMK
                     RMEEKRIPADIDWDDIDSIATEARQKFKLISPETIGQASRISGVNPADISILMVYLEG
                     RSRSISKNKSKDSH"
     gene            25582..27543
                     /locus_tag="AC1PIV_000427"
     CDS             25582..27543
                     /locus_tag="AC1PIV_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HIP6611477.1"
                     /translation="MKRFRFSTIHFVMICVILFGLVALVHRFFPIGASTVFALLISLL
                     VLIALFIYQKHSYEFSELEQIEYLNNQANSGLMMLLDKMPVGVIKVRPDSNQVEWFNP
                     FAELIFAQENGEFDQKKLREIIDVGLDEERIYANFSGKRYAVNVDFDQGLFYFFDAST
                     EYSATNSLIGSRPVIGIISVDNYDELEDAVTDSQISQVNSFLAQFVSEFCHDYGIYYR
                     RGTMDRFYFFTDYAVLEKLIENKFSVIDKFREEAKKLDLGLTLSMGLAYGNENHHQIG
                     QVALQNLNMAEVRGGDQVVVKENDESKQPLFFGGGSASSVKRTRTRTRAMMTAVSDKL
                     KSVDAVFVVGHRNLDMDALGSAVGMQYFAQNIMNNAYTVYNPDEMAPDIARAIKKLSD
                     ENCSNLLTVEEAMKMVTFQSLLIMVDHSKIGLTLDKDFYEKFTQVVVVDHHRRDTDFP
                     NNAVLTYIESGASSASELVTELIQFQNDKHHKLNRIQSSLLMAGIMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSLEIQQIAATDFEEYRQINELILSGQRIESNVVIACADDTKEY
                     DNIIPSKAANTILDMAGIEAVFVVTRNIKGYVSISARSHNKINVQRIMEEMGGGGHFN
                     LAAAQVYDQTIAEVCEKLTDKIREEINGN"
     gene            27554..28006
                     /gene="rplI"
                     /locus_tag="AC1PIV_000428"
     CDS             27554..28006
                     /gene="rplI"
                     /locus_tag="AC1PIV_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HIP6611478.1"
                     /translation="MKVIFLADVKGQGKKGEIKEVPTGYAQNFLIKKNLAKEATNQAI
                     SALRGQEKSKEKAHAEMIAEAEAIKAKLAEEATLVKFVEKVGPDGRTFGSITSKKIAE
                     ELDKQFGIKIDKRHIQLDHPIRAIGLIDVPVKIYQDVTGIINLSIKEA"
     gene            28038..29393
                     /gene="dnaB"
                     /locus_tag="AC1PIV_000429"
     CDS             28038..29393
                     /gene="dnaB"
                     /locus_tag="AC1PIV_000429"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HIP6611479.1"
                     /translation="MAELDELRVQPQDILAEQSVLGAIFLDEGKLVFVREYIEAEDFF
                     KHAHKLIFKAMIALSDRNEAIDATTMRNYLVNHGDLENIGGLAYLAEIISSVPTAANA
                     EFYAKIVAEKSNLRKLIARLTDAVNQAYEGTDGSDDIIANAEKALIDVSEGASRSGFK
                     RIDDVLNINFDNLETRAKQTSDITGIATGYPALDAMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLGLTVAIFSLEMGAESLVDRMLASEGVINSRAIRTGHLTQEEWNKY
                     MVAQANLARASIYIDDTPGIKITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGEQEDGGIPNNTVEVIIEKNRSGARGTVELMFQKEYNKFASISKRED
                     G"
     gene            29397..29648
                     /locus_tag="AC1PIV_000430"
     CDS             29397..29648
                     /locus_tag="AC1PIV_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018164720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HIP6611480.1"
                     /translation="MSDAFTDVAKMKQIKQDIKDHEGQIVELTLENGRKREKNKQGRI
                     VEVYQSLFIVEFEDPNNTFVESYTYSDILTEKILIHYLD"
     gene            29956..30567
                     /gene="rpsD"
                     /locus_tag="AC1PIV_000431"
     CDS             29956..30567
                     /gene="rpsD"
                     /locus_tag="AC1PIV_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HIP6611481.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFSYGLGEKQFRNLFVQATKIKQGTLGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVEVGQVISVREKSIKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            30633..31082
                     /locus_tag="AC1PIV_000432"
     CDS             30633..31082
                     /locus_tag="AC1PIV_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol reductase thioredoxin"
                     /protein_id="HIP6611482.1"
                     /translation="MWRKYFLLVLLAILVVGGAFFLSQSAATPNESDYVKAVKSYQAI
                     SIDEVEQKVQDEEEFILYIGRETCPYCRDFVPKLTEAVEQSHATIYYLDSESDPNGKI
                     QQFRQSQGLATVPSLTYYKSGKLSGILRKGSQATLSEIENFLALQGQ"
     gene            31215..32732
                     /locus_tag="AC1PIV_000433"
     CDS             31215..32732
                     /locus_tag="AC1PIV_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HIP6611483.1"
                     /translation="MKKKAWLGLLMSLLAVLFLVACGGKSEKTATSSSSTTSSSSEEA
                     VSGASEKVYTDPSELKDSYDVIVVGSGGAGMSAAISAKDAGASVALLEKMPVIGGNTA
                     KSSAGMNASQTKFQEAEGIADTNDKFYEETLKGGKGTNDPELLRYLVDNSASAIDWLD
                     GMGITLSNLTTTGGMSEKRTHRPADGSAVGGYLVNGLYHNLVEREVPIFVNADVTKLQ
                     DKDGAVTGVEVKIAGETKKISAKAVVLATGGFGADLEMVAKLNPALKGYVTTNQEGST
                     GDGIALAESEGAATVDMEQIQIHPSVEQETSYLITEAVRGEGAILVNSKGERFVNELE
                     TRDKVSAAINSLDPNYAYVIFDDALKDRVKAIAQYEEKGLVKTGATLADLAKEIGVPA
                     DALQTTLDTWNKAVADKNDAAFGRTSGMDHALNTGSYHAIKVAPGVHHTMGGVKINTN
                     TEVLKTDGSAISGLYAAGEVTGGVHGQNRIGGNAAADIIVFGRQAGEQAAGFAKK"
     gene            32818..34164
                     /locus_tag="AC1PIV_000434"
     CDS             32818..34164
                     /locus_tag="AC1PIV_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HIP6611484.1"
                     /translation="MKKKIVLLLGAIAVIVLTWSAITGQRQQSYAEAELRDQDKIWII
                     TDLHYLSQDLFDDGEAFSYIEKTAAGKDLRYGKERMEALVEQVEREQPSLLLVSGDLT
                     LNGEKQSMVELAQYFTRIEEKGTEVLVIPGNHDIASGWARAFKGDQQIVTDQVTAQQF
                     AELFVNHGYQQASSRDKASLSYLAKPFSNAWFLMIDSNIYSDGYGKGAPPTNGCIKKE
                     TLEWIEVQLQAAKEAGVSLLPVVHHNVLQQHAMLSKGYTLDNAADLKALFDQYGIHFG
                     FSGHTHSQNIVKEDLGQVNYTEVVNGAFSIYPAIIGQLSLDDTSIHYQKTQLDMASWA
                     EKHQPSDPNLQDHVTYLQTVFDNTSDIMVHNVLNDERWYDGETADAISQFIMPANRAY
                     FSGEKLDQTWLDEKVFPSQAYQTLQAASPRSFLADYLDVIIKRSQSRDVEQVTVSK"
     gene            complement(34203..35510)
                     /locus_tag="AC1PIV_000435"
     CDS             complement(34203..35510)
                     /locus_tag="AC1PIV_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HIP6611485.1"
                     /translation="MINFPDIPRFYTALTESLACLLVCSSLVLSEKWSRKQVRILLIF
                     LIQILLQLAAGKLPLLLWTVGMGTNIAWMFVSVRFLGVIHKRTSLYLTAKAFIIAELV
                     ASITWHLYCLTIYQQPVDNLWTQGLFLLITSLLSYWLIYLQDQKVRLEELDKFIEQRD
                     VTVAVFTTLSIFVLSNIGFILSGTRQFQDSTSIFILRTTVNLSGLLLLFTQESQQYDR
                     YLRQELTSINNIFQLQYKQYQAYRENSEILDRKVHDLKHQLAIIQQESDKTKKEQYLE
                     EMSEVIQTLDAKIETGNPVLDTILSQKNYYCLQNGINFTCIVQGEPLHFMDVMDISAL
                     FGNAIDNAIEAVEKIDNPEQRLITLKVASHQQFLIIRLDNYDTSSLDLSTGQLPETSK
                     TNKDYHGFGLKSMEYVANKYGGSLTLSKEDNWVQLKIILPLQV"
     gene            complement(35507..>36227)
                     /locus_tag="AC1PIV_000436"
     CDS             complement(35507..>36227)
                     /locus_tag="AC1PIV_000436"
                     /inference="COORDINATES: protein motif:HMM:NF012301.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HIP6611486.1"
                     /translation="CFMKIAIVEDQKIEQDRLSNYIKTYCKKAGIAVEISCFNDGLHI
                     TSDYQKQFDLIYLDVEMEIMDGMTTAQKIRNLDKEVLLVFVTNHSHVAIQGYSVEAID
                     FLLKPLSSFVFEEHFKKILRKLPDSQEKQSLYIKSKQSTVKLYQEDIVYLESQGHQVH
                     IYTVDSGLTITHNSLKNLEAMLNSKLFVRAHSAYIINLSHVQKVEGSLVYVTNTALPI
                     SRPRKKEFMTALTNFIGDSLL"
BASE COUNT        10802 a         6400 c         8171 g        10854 t
ORIGIN      
        1 attttatttt acattaaaca aagcactctg tcaatacaat aaaaaatcaa aaaatgtatt
       61 gacaaacaaa gtcacatgta ttatactagt tattgttcta aaaatggtcc gttggtcaag
      121 gggttaagac accgcctttt cacggcggta acacgggttc gaatcccgta cggactattt
      181 cttccgccat agctcagttg gtagagcgca tgactgttaa tcatgatgtc acaggttcga
      241 gccctgttgg cggagtagat aaagcatagg aaaccttgag aaatcaaggt tttttgtttt
      301 ttacaagaaa aaaccgagaa agtttagtat tctcggttct tagaataata gtatccaatg
      361 aattgatagg agaaaaatac aaaaactgca ccaaaagaaa tcagtaaacc tagatagaaa
      421 ccatttggta caaaggttaa aactagttta gtttgacctg gacttacatc cactttcata
      481 aaaccatctt gcgctttttg gattttgata ggtttaccat caatggttgc attccatcct
      541 ttatcatagg gtaaagtaag gaggagtgag gattctttat cggttacaaa atcaacagtt
      601 actttattac catcagtttt tgttactact tgtttttctt ggagaatgga aatagcctgt
      661 tggaaagcta ataagtccaa tcgataaaat tgtggtttat caaaagaaac ttgattattt
      721 tcaggaaaat atacattgac ttgaacctgt acatctgtag taaagctccc cacattgaag
      781 aaagagaaag cattatctag tgtaaactca cttgactgat tgttgacagt aatgacaact
      841 tttttttgat tctcatttga gaatgttaaa tttggcaaat ttaagtatac ttggctattt
      901 gcaggtatat ttactaagaa agttgctttt gcagcatcct cattgtccac tttgttgaca
      961 gtcattcgat tgctcagttc aactgtattt tgtgaaacaa catctgataa agtgtggtag
     1021 tatttttgag atagccctgt tagttgatta agaaaatttg tttgattatc gagagtcaga
     1081 tttgtaaaat tgacatcttt gtaaatccct tcagtcaata gggctaaccc tagattaaaa
     1141 ctattttcgt aaagattaat agtagactga ctctgattca gtgtgaaacc aaacttattt
     1201 gggtccgtag tagctaaatt atatttgact ccgaataggc tatcagcaat gattgtatta
     1261 ttctgatagc gaagattcaa attggtacca tctgaacgga aaccgagctt atctagtact
     1321 gagctggaag cacgatttcg aatggaggag aattgagaaa taccgttgta attgaatttc
     1381 atgctatcat tgccagtttg tggtaataga cgttctatac gataaaatga atcagttgta
     1441 gtctttgtag actttacaat actgtcaata tctgtcaatt tttcttcata gtttgatcgg
     1501 ctaggaaaat gccattcatc agaaatcccc tgaacctgat aatgactatg taatccaagt
     1561 tctaagaaag tgaagaacaa taaaacaata ttaatccatt ttaaggatga tttatagcga
     1621 atcattgcta caaaaagaat gaagtaggct attagaaatt ctagtgtgag taggaaattt
     1681 acatccgtta gaaactcata atgatctcta aaaataaagg tagaagtaaa gcaaatgagt
     1741 aaaaatgaaa caatcagagt aaaattttta atacttactt gacgtagtcg taccaatgtc
     1801 tctgctgcta aatagataac ggttattgat agagcccatg cataacgata gaggaacatg
     1861 tttggcgcat gcataccttg ccaaaaaaga ttgagtggtt gtaggtagaa acttgaaata
     1921 atgaatgtaa agaatagagc ataggagagt ttgacagttg gttttatttc ttttaatgta
     1981 aagaataata aagcgagtat taatggaacg agaccaacag agatcatggg aatagaaccg
     2041 aattttgttg tatcaaagct accaactaag ttttttgcaa agaagtccag ataccaagag
     2101 tcttcggttt ttaggttgac aatttttgta aatgtctcac catgagtttt taaatccaag
     2161 taggttggta acaacatgaa catgctgctt agagcagata aaattgacac tattgtaaag
     2221 ttgataaatc ttttgattct ctgactatct atccatgata attgaaccaa tgtccataat
     2281 gttagaaaaa tagccaccat ataaccgaag taatagtttt ggataaacaa gcatgttaat
     2341 gttatgtagt agagaatcgg accctgtttt tttaataatc gatgcaatcc aagaagaacg
     2401 agtgggagga gtataaaaac gtctagccag ttgtttattt ctaattgact tgtactaaaa
     2461 ctcatcagag aaaaactagt agcgagtaat agtgcccatt cttctttcaa atttttatgg
     2521 atacccttta gactgaaata agttgacaac ccagtcaatc caaatttgac aatagtgaca
     2581 aggtagatag cgtcaggcat ggattgtaaa tcaaagaaaa agacaattgg agataggaat
     2641 gaacctaggt aataggagga tagagcataa aaattgagtc ctaaaccact tgaaaatgtg
     2701 taaaataaag agccgtctcc gtgtaaagta tttcgtaatg tttgattaaa aataacatac
     2761 tgatggaaac catcactggc caatattgtt gtatcacttc cccaccagat tccttgaaat
     2821 gctaagacga tagaaataat agtcagcgga ataaggaaag ataagagata ataaatggat
     2881 gtttttgtaa atattttttt catagattta aaagaaaagg aagtgggaaa gaacttgacc
     2941 ggtcaaaaaa gagttcgtca acaagtcttt atttctagtt gttgagctga aacagtctat
     3001 tcccagactg tttcactccc acccccgcac agctcaaact gtctgggaga cagtttgagg
     3061 ttggagataa ggcgaacttt gttcgcaaca gtcgtaatgg ccagatttgg agtgtgaaac
     3121 acgaacaaat ctggcaatca accactgcgc tgagatgttg acacgaactc tgagaagaga
     3181 ggctgggcaa aagtcccagc ctctttttat tatgctttcc aaagttcttg tacttttgct
     3241 tgtacttcag cattttccaa gaattcatca taagtttcgt cgattcggtc gataacaccg
     3301 tttttagaaa tgacgatgat atggtttgct aaagtttgaa taaattcgtg gtcatggctg
     3361 gcaaagatga tggactcttt aaaagctttc aaaccatcgt tcagactgga aattgattcc
     3421 aagtccaagt ggttggttgg atcatctaag accaagacat ttgacttgag gagcatgagt
     3481 tttgacaaca tcacgcgcac tttttcgccc cctgacaaga cgtttacagg tttgttaacc
     3541 tcatcacccg agaagagcat acgtcccaag aaaccgcgca agaaggtatt gtcatcttct
     3601 tccttgctgg caaattgacg gagccaatca aggatagatt cgtttgtatc aaagtcacga
     3661 gtattgtctt ttggtaagta ggattgacta gtagtgacac cccacttgac agtaccttca
     3721 tattcaatat cgcccataag agcacgaatg agagcagttg tttggatgtc gttttgacca
     3781 ataagagcag tcttgtcacc tgggcgcagg ataaagctga tattgtcaag aatcgtttca
     3841 ccatcaataa caactttcaa gttttcaact gttaagaggt cattaccgat ttcacgttct
     3901 gatttgaagt tgataaatgg atacttacgg ctagaaggaa tgatttcttc caactcgatt
     3961 ttgtccaaca ttttcttacg tgaagtagct tgcttagact tagaagcatt agcagagaaa
     4021 cgggcaacga attcttgtag ttctttgatt ttttcttctg cttttgcatt acggtcagct
     4081 tgtagtttag ctgctagttc gctagattgt ttccagaagt catagttacc aacgaaaatc
     4141 ttgattttac cgaagtcaag gtcggccata tgggtacata ctttgtttaa gaagtggcgg
     4201 tcgtgtgaca cgacgataac cgtattttca aagtcaatca agaaatcttc gagccagttg
     4261 atagattgga tgtccagacc gttggttggc tcgtccaaaa gaagaacatc tggtttacca
     4321 aaaagtgcct tagccaagag gaccttaacc ttctcaccgt tggtcaattc gctcatgttt
     4381 tggtagtgga ggtcttctga aatgttgagg ttttggagca attgagaagc ttcactttca
     4441 gcttcccagc caccaagttc agcaaactca ccttctaatt cagcagcacg aacaccatct
     4501 tcatcagaaa aatcttcctt catgtaaata gcatcttttt ctttcatgat gctgtaaagt
     4561 tgctcattcc ccatgataac tacgtcaatg acgcgttcgt cttcatagtc gaaatggttc
     4621 tgacgtagta cagaaaggcg ttcgtctggt ccaagtgaaa tatgacctgt tgatggctcg
     4681 atgtcaccag caagaatttt caaaaatgta gatttaccgg ccccgtttgc accaatcaaa
     4741 ccgtaggtat ttcctgctgt aaatttgata ttgacatcgt caaataattt gcgatcgcta
     4801 aagcgaagcg acacgtctga tactgtaagc atagtttctc ctctatttct gtctattagt
     4861 tttattgtac tagaaagaac ttgaattttc aatgaattac attggaatca aaatatcttc
     4921 atcataatgt ttatggtctt tttgaagact gaagccacgt ccacgcacct gactcgcagg
     4981 cataacaacc ataaaggcag tttcatcaat ttctaatacc gctgtctcaa gtttctgcat
     5041 ttctggaata gagatggtag tcatcaacat gcgcttgtca actcctgtaa agccaccgat
     5101 aattggaagt tctgtcacac cgcgatcagc aactttagta atatagtctt taatttcttc
     5161 tgatttttga gaaataatca tgacatttcg agaagattgg gtaccagaca tcatgcggtt
     5221 gacaatataa gtaatggtca ttagggcaat aatcgagtac ataacagtat cagtatcgaa
     5281 ggcaacaaat ccaagaccaa cgataatacc atcaataata gccattgtca gacctaatga
     5341 taaaggggtg tacttgtgaa taaattgaat aagaatacct gttccaccag tagaagaatt
     5401 tccaaggaag acaagcccaa gtccaaaacc taggataatt ccaccgaaaa tagcagctag
     5461 gagaggattt tctgtcaagt tgggtaaacc tgctgtcaac ttgatgcaaa gaggatagat
     5521 gatagcacca tagacagttt tgataaatac agattttcct aagaaaaacc aacagatgat
     5581 taataaaggg atgttacagt agaggacaaa atcagacgga ctccacctca gaagagcatt
     5641 gagtgcgatt gctaaacctc cgacaccacc agatacgata ttattctcta gaaaaaaact
     5701 gttaaatcca atggccatga caactgatcc gagtgtgaca gagataaagt cctttatacg
     5761 ttctttcata tattctcctt ggttagtgtt ataaaagcaa tttctattat ccctaattta
     5821 gacagtatcg tcaaggcttt gtcagcttga ctttctaatt ttttgcggtt ataataggaa
     5881 tcaatcagaa gagtagtaag tggataattt ttagagagtt tgtggttggt gtaaacaaac
     5941 aagagtcgct tatgaatgga ctgagtgaat agaatctgaa taaataagga ttcggctagc
     6001 aggccttatg tgcaaaaaga tgtaagctta tttaatgctt ataagtgagg tggcaccgtg
     6061 tccttgacgc cctcgcacag ttttctgtgc gtgggctttt attatgtaaa aggagaacat
     6121 tttatgagta aaccgattat cctaacagga gaccgtccaa caggcaaatt acatattgga
     6181 cattatgttg gttcgttgaa aaatcgtgtt ttattacagg atgcaggtca acatgaactt
     6241 tttgtctttt tagcagacca acaagcgttg acagatcatg caaaggaacc gcaaaagatt
     6301 gttgaatccg ttggaaacgt agcactagat tatctagcgg caggacttga tccagctaag
     6361 acaacgattt tcatccagag tcaaattcct gaattggcag agttgaccat gtactacatg
     6421 aacttggtat ctgttgcacg tctagaacgc aatcctacag tgaagactga gattgctcag
     6481 aagggatttg gcgaaggaat tccagctggt tttttggtct atcctgtgtc acaagcggcg
     6541 gatattacag ccttcaaggc aaactttgtt ccagtaggaa atgaccagaa acctatgatt
     6601 gagcagactc gtgaaatcgt tcgtagcttt aaccatgctt accagactga tattttggta
     6661 gagccggagg gcatttatcc tgaaaatgag gcagctggtc gcttgccagg tttggacggc
     6721 aatgccaaga tgtctaaatc acttggaaat ggtatttatc tggcagatga catggatacg
     6781 ctcaagaaga aagtcatgtc catgtacact gatcccaacc acatccgtgt tgaagaccca
     6841 ggtaagattg aaggaaacat ggttttccac tatcttgacg tctttgggcg cgaagaagat
     6901 aaggctgaga ttgaggctat gaaggagcac tatcaacgtg gtggtttggg cgatgtgaag
     6961 accaaacgtt atttgctgga cattttagag agagaattag gaccaatccg tgaacgccgt
     7021 ctggagtttg cacaggatat gggacaggtc tatgcaatgt tggaagcagg tagccaaaga
     7081 gctcgccaag ttgctgcgaa aactcttgac caagtgaaat ctgctatggg aatcaactat
     7141 tttaaataag gttaacaatg aaagagcaat gttgagaaaa tgttgttttt ttcatttgtt
     7201 ttacgacgta gcaaaaaaca aacgttcgaa ttttatgtat aagactgaat agaattttct
     7261 gaatttttag gaatgatgat attaaagcga ataatgattg acaaatgatt tcaaaatgtt
     7321 atcataatta aaatacaaat agcaatcatg ctacatatta aataagaaaa gaggaagaaa
     7381 atgtcaaact gggacactaa atttttgaaa aaaggcttta ctttcgacga tgtattactt
     7441 attccggctg aaagtcatgt attaccacat gatattgatt taaaaacaca attagcacca
     7501 aatttgaccc ttaatcttcc gattatttct gctgccatgg atacagtaac agatagcaaa
     7561 atggctatcg ctatggcgcg tgcaggtggt ttgggcgtca tccataagaa catgtctatc
     7621 gcggagcagg cagatgaggt gcgtaaggta aaacgttctg aaaatggtgt cattatcgat
     7681 ccattcttct taacaccaga acacaccatt gctgaagctg agaaattgat ggctacttat
     7741 cgtatttccg gtgtgccaat cgttgaaaca ttggaaaatc gtaagttggt cggtattatc
     7801 accaaccgcg atatgcgttt catttcagat tactcacagc caatttcgac caacatgaca
     7861 agcgatgaat tggtgacagc gccagttgga acagatcttg cgactgcgga ggctattctt
     7921 cacaagcatc gtattgaaaa attgccattg gttgatgaaa atggtcgttt gtcaggcttg
     7981 attaccatca aagatattga gaaagtgatt gagttcccaa atgctgcgaa ggatgaattt
     8041 ggtcgtctct tggttgcggg tgctgttggt gttacatctg atacttttga acgtgcagaa
     8101 gccctttttg aagcgggtgc agacgcgatt gtcatcgata cagctcacgg tcactcagca
     8161 ggcgttcttc gcaagattaa agaaatccgt gaccacttcc caactcgtac cttgattgcc
     8221 ggcaacattg ccacagctga aggagctcgt gctctttatg aagctggtgt tgatgttgtg
     8281 aaggtcggta ttggaccagg ttcaatctgt acaacacgtg ttatcgcagg tgtcggtgta
     8341 ccacaagtga cagctatcta tgatgcagct ggtgttgcgc gtgaatatgg taaaacgatt
     8401 atcgctgatg gtggtatcaa gtattcagga gatattgtca aggcacttgc cgctggtggt
     8461 catgccgtta tgcttggttc tatgtttgca ggaactgatg aagcaccagg tgagacagaa
     8521 atcttccaag gtcgtaagtt caagacctat cgtggtatgg gctctatcgc tgccatgaaa
     8581 caaggttcaa aagaccgtta cttccaagca tctgtcaatg aagccaacaa acttgttcca
     8641 gaaggaattg aaggacgtgt agcctataaa ggttctgttg cagatatgat tttccaaatg
     8701 gttggtggac ttcgctcagg tatgggctat gtaggtgctg gtaacttgac tgaattgcat
     8761 gaaaatgcac aattcatcga aatgtcaggt gctggtttga aagaaagcca tccacacgat
     8821 gttcaaatca caaacgaagc tccaaactat tcagttcagt aaaacaaaaa caagaccctc
     8881 ttggcagggt ctttcagatt gaagaaaaag tccattttgg acaattttct tcaatctttt
     8941 tttctttata ttgaaaataa aaaaactctc agaaacgccg aaatatcaat atttctaaga
     9001 gtttaataac ttgctatctt tcgcaaactt cttcaatttt ttatattttt aggagtttgt
     9061 ctacgttctg caagaccctc ttgacagggt ctttactttt ttgtaaactt tattgacgat
     9121 agtgtaaaca atcttattct gactcagtaa ccttaccaga ctcaatatgg aagattttta
     9181 aactatcagg tagcttatgt aaatggtcta aagatgtcgt tgtaataaat gtttgaatcg
     9241 tatctgtaat agtttctaat agtttgattt gacgattatt atccagctca ctcataacat
     9301 catctaagag tagaattggg tactctcgtg tgacttcttt catcagctca atttcagcta
     9361 gtttgagtga cagaacgaga ctgcggtgct gaccttggct agcataatgg gcattcattc
     9421 catttataaa gaaagctaca tcatctcgat gtggtccaac tcctgtattt ttcttaaata
     9481 aatcacgttt acgagacttt tctagttccg tcaagaattt gtcaattaaa ttgacatcat
     9541 ctgtcaattc gattgaggtc tggtattcga ttgtcaattc ttcccgattg ccagatattt
     9601 cttgaacttt tctatttccg aattcctcta atttctttag aaagtcaata cgatgttgga
     9661 taacacgact accatattca gcaagttgct gatctaacac agataggaag ttctcatcaa
     9721 tcttatctgt agatttgagg taagtatttc tttgttttaa aacgtggtta taattcgata
     9781 ggtcagagag atagagtggc ttgatttgcc cgagctcgac atcgatgaac tttcttctca
     9841 aagcaggcgc accttttatc agctgtaaat cttcaggggc gaagagaaca acattcatgt
     9901 ggccgatata gttggaaagc ttggcttgtt tgagatggtt gaccttggtc actcgtccct
     9961 tgtctgtcaa gtgaatgtca aggggaactt taccgcttgt gcgatggagt aaaccagaaa
    10021 tagataattc cttttcttga aactgtagta ggtccttatc tgtccgtgtt cgatgacttc
    10081 gtgttaaggc taaaacatag atagattcta gaatattggt ttttccttgg gcgttttcgc
    10141 ctaaaaagac attgagccct ttgtggaact caatatctaa ttggttgtaa ttgcgaaaat
    10201 gttgtaactc taatcgttct agccacatgt ctacatacca gggaaacgaa caggttttct
    10261 ttcagtcttt ttagttgctt ttttaggagt ttttacctgt ttcttattat ttttattttc
    10321 ttgatttaac tttttaacga ttgcagccac acgttctttt tcagcttgat cctcttggtg
    10381 ctgtttgatt tcctctgcac taggagcgac gattgtgatg ctggtgttgt ggtctgggag
    10441 tgtgataaca tctccgacac ggattttttt accgcgtctt ttttcatcct ctccattgaa
    10501 aagaatggta ttttcttcta agaaaccttt aatggcacct cctgaatgga gaataccagt
    10561 cgtttttaac aatgcttgta atgtgatgta gtcatcaaat aatttaaatt ccataagtca
    10621 cctcgttaca gaatattata tcacaaaatg gtataatgga aggtacaatg tttgaaagag
    10681 gaagacgatg aaattacaag agggagtaga tcttcatttt attgatacag atcagtttac
    10741 gacaaatcgt atacgtattc gctttgcagc tgaaatgagt gaggctacag ttgctggtcg
    10801 tgtgttagtt gcaaatattt ttgaaatggg taaccaagaa tttcagactg ctcaggctgt
    10861 tcggagaaga ttggcagaat tgtatggtgc tcagttctcg acctcagttt cgaaacgtgg
    10921 tagggtgcac tgtgtagatg tgacaatttc atatgtcagt cctcgtcact taccagaaaa
    10981 tgaggatatt acagtggaga ttcttgattt tttatacaca tgtatattta gaccactgaa
    11041 aaaggggcga ggatttgata gccagatttt cgaggttgaa aaaacgaatt taatcaattt
    11101 tcttcagtca gagatagaag ataattttta tcatgtagat gttgaaatga gtaagctttt
    11161 ttataaagat ccctctcttc aaattccacg cgtcggtagg cttgatttgg ttgaaaaaga
    11221 aacagcagaa tcaacctttc agatttatcg gaatatgttg cgtatggata aaattgatat
    11281 atttgtctta gggaaggttg acagagaaca agtaaaaaga aaacttgaag attttggttt
    11341 tacttataga aatccaaaat tagagttaga atatcatcag gaatactcaa atatcacgca
    11401 agaaaaaatc gagcgtaaac aggcaaggca gtccattttg gaattggcat atcatttaca
    11461 ggtggtttac aacgatgtaa actatccggc tttgatggta tttaatggtc tactgggtgc
    11521 tttctcccat tcgaagttat ttatgaatgt tcgtgagaaa gaaagtttgg cctatacaat
    11581 tggtagtcag gtctctattt tttcaggaat gctaaaggtc tatgctggaa ttagccgtga
    11641 aaatagactc agggtaatga agttaattag taaacaacta cttgatttaa aatgtggtaa
    11701 gtttacagaa gaagaattag agttgacaaa aaacatgttg attcattcag caaccttggc
    11761 tcaagatagg cagaataatt tgatagaaca agtatataat caagttacct taggaaatag
    11821 aaatttaagt tggttagatt ggattgaggc tatcaaatcg gtatcaatag acgatgtcat
    11881 tcaagtagga cagatgatta atttacaggc tgtttacttt atggagggga cagaagaatg
    11941 aagttagttg agaagaagta tccttacatg aaagaatctg tcttttatgg gaaagttgac
    12001 aatgggttga cagttatttt gcttcctaaa gtagatttcc atgagacata tggaattcta
    12061 acgacaaatt ttgggggtat tcatactcga tttacattgg ctaatggtaa tagtgttgtt
    12121 tatcctgcag ggattgcaca ttttttagaa cataagctgt ttgaaactga gaatgaagag
    12181 gatattatga atgagtttgc taaattggga gcaagcgcaa atgcttatac cagttttaga
    12241 cagactagtt acttattttc aacgactcag aaagtattgg agtctctatc acttttacaa
    12301 tcttttgttc gagaaccgta ttttacagaa gacaatgtag aaagagaaca ggggattatt
    12361 gaacaagaaa tcgagatgta tcaagatgat gcagattatc gcttgtttac gggaattcta
    12421 tcatcgcttt atccagaaag tcctttggcc tatgatatag cagggacagt tgaatcaatt
    12481 gctgcaatta ctgcggatga tttacatgag aattttgatg tgttttatca tccaagtaac
    12541 atgaatttat tcgttattgg taattttgat ttagaggcag tttggaaaca aatttcaagt
    12601 tatcaagtag ctcagatgga taatccagct cagtcgtttg aattggcagg tatccaaaag
    12661 ttgccgatac aggaacatct ctcagaacaa tttgaagtat ctaccccaaa attggctgtt
    12721 ggtttacggg gaaatgacga ggttgataag gagactattc agaaatatcg gcttagttta
    12781 caatttttat ttgccatgtt gtttggttgg acttcaaaac gctatcaaca gttatacgag
    12841 cagggaaaaa ttgattcttc tttccagttc caattagagg ttacacctga ataccactat
    12901 ttgattatct cgggagatac tcaagaaccc attacgcttt ctagtatact gatgaaagca
    12961 cttaggaaat ttgaggatga tgcagatgtg acagaggatc atttacaatt gttgaaaaac
    13021 gagatgtatg gagattttat tcgtagctta aattctcttg agtttacagc tagtcacttt
    13081 gtttctcagt attcagaata tgaaaatgtt tttgatatac ctcaaatgat acaaagtctt
    13141 cagttagatg acatcagaga ggcaggtcgt cgctttattg atcactgtga tatgacagat
    13201 ttcacgattt ttccaaaata agtgggcgca acccgtcgaa atttccttgg aattttgtta
    13261 gaatagtata ctgtacatga tgagcgatag agagagggta ttatgagaca aaagagtata
    13321 ggggaagtac ttagaacagc cagagaagga cggggttgga catttgttga cttgcaacgg
    13381 ataacaaaaa tccaagctaa atatttgcag gcacttgagt acaatgattt tgattttatt
    13441 gcaaactcag atgttgttca gtctatttta aaagcatacg ctgaggcttt ggaattagat
    13501 gcagatgttc tactggatgc ttacgagacc aatagtttag tgaaatatta tgaagatgga
    13561 gaagaagaac tacgctcttc agaattgaaa agaagctata aggttcgtaa acgtaaaaag
    13621 aactcttatc ttccgttgat ttacttatta cttgcgacgg ggttgattat tatttttgtg
    13681 atttatattg ttcatagcag gctcaaaaat agagcatcta ttacgcctac tacaacgtca
    13741 tatagtatag ttgagcaatc tgtatctgaa gcaagtagtg gcacagagac gagttctact
    13801 gagcaggcgc agtcaaattc aacgagttca agtagttccg ctacagaaaa tgtgactatt
    13861 tcaggatcag gttctaacat tgttgcgacc cttaaaacag tgacttatcc agtagaagta
    13921 actgtaacag caaaaaatac aacgagttgg atcagccttt ctgacacctt gttagagggg
    13981 ggcgttacac taacacctga taatccaaca gtaactacta ctattgaaga aggagtgact
    14041 tctactacac ttattcttgg tgttgttaaa ggggttgagg taagtgtagg tggtcaaaag
    14101 ctagaactat cagctctgac agcagataca ggctcaatta caataaattt tgaacaataa
    14161 aggttttata tgaaaaaaga aaatattccc aatgcattga cgataggtag gattttggta
    14221 attccaattt ttatcttgtt actgaccgtt tggaattcaa caattagtca tgtcttagca
    14281 gcacttattt ttgcattagc tagtattacg gattatctag acggctactt ggctcgtaaa
    14341 tggcaggttg taacaaactt tggaaaattt gcggatccga tggcagataa gattttggtg
    14401 atgacagcat ttatcatgct tgtagagctt ggctttgctc cagcttgggt agttgcaatt
    14461 attatttgtc gtgaattggc agtgacaggt cttcgtctac tcttggtgga aaatggagga
    14521 acagttctag ctgcggctat gccaggaaaa atcaaaacat tttcacagat gtttgcagtt
    14581 attttcctgc tcttacactg gaacgtcgtg gggcaaataa cactctatat tgcacttttc
    14641 ttcaccctat attctggcta tgattatttc aagggtgcgt ccttcttgtt taaagataca
    14701 tttaaatgat gaatattatt gaagtaaaaa atttaaaata taaatacaac caagaggatg
    14761 agcaatatac tctaaatgat gtttcgtttc acgtgaaaca gggagagtgg ctatctatta
    14821 ttggtcataa tggttcgggt aaatcaacaa cagttcgttt gattgatggt ttgttggaag
    14881 ctgaatcagg tgatatttat attgacggtg atgccttaac cattgataat gtatgggata
    14941 agcgacgctt gattggtatg gtttttcaaa atccagataa ccaatttgta ggcgctacag
    15001 ttgaagatga tgttgcattt ggtttagaga atcagggaat ccctttggag gagatgcgta
    15061 gtcgagttga cgaagctttg gaattagttg gaatgactga tttcaaaaca cgtgagcctg
    15121 ctcgtttatc tggtggtcag aagcagaggg tggcgattgc tggagtggtt gccttgcgtc
    15181 caaaaattat tattttggat gaggctacgt ctatgttgga tccagaaggt cgtctcgact
    15241 tgattaagat tgtccgtgaa attaaggagc gtcatggtat gacggttatc tctataacac
    15301 atgatttgga tgaggttgca ttgagtgatc gagttatcgt gatgaaaaat ggacaggttg
    15361 aatcaattag cactccaaat gaactattta tgcgagaaga tttggtagat ttagacttgg
    15421 atagaccgtt tacgacagaa ctggcttcat ctttgcgcca gactggactt gatttaccgc
    15481 tccgctattt tacagaggaa gaattagagg aaactttatg ggaattgatc tccaagaagt
    15541 aagctatacc tatcaagctg gcactccttt tgaggggcgt gcgctttttg gtgtggattt
    15601 ggagattgtt gatggctctt acacggccct tattgggcat acgggttcgg gcaaatcaac
    15661 gattttacaa ctcttgaatg gattaaatgt accaacagaa ggaagagtag ttattgatga
    15721 tgttgtgatt acagcgacgt ctgaaaataa ggatattaag caagtcagga agaaagtggg
    15781 gttggtgttc caatttcctg aaagtcaagt gtttgatgaa acggtcttaa aagacgttgc
    15841 ttttggtcca caaaatttcg gagtttctca ggaagaggct gaaacgattg cgcgtgaaaa
    15901 gttggccttg gttggaattg atgaaagctt gtttgagcgt agtccttttg aactatctgg
    15961 tggtcaaatg cgtcgggtag ctattgctgg gattctggca atggaaccaa gtatcttagt
    16021 tttggatgaa ccaacggctg gattggatcc tgcgggtcgt caggaattga tggatatttt
    16081 caaaaagctt catgaatcag gcatgacaat cgttttggta actcatttga tggacgatgt
    16141 ggctaactat gctgattttg tttacattat ggaaaaggga aagctggtcc gttctggtaa
    16201 accagtcgat atttttcaag aggtagattt tttagagagt attcagttgg gagtgcctaa
    16261 gattactaag tttgcagcta atttggagag aagaggcttt gtatttgaac gtcttcctat
    16321 tacaattgaa gaatttacgg ggatggtgac acatggataa attaatttta ggtcgctata
    16381 ttcctgggga ttcaattatt catcgcttgg atccaagaag taagctttta gcaatgtttg
    16441 gatttctatt gatgattttt tgggccaata atttggtcac caatgccttg ttgatagcat
    16501 ttgttttagg aatggttgtt ttatcacgta ttcgcttatc attttttatt aatggtttga
    16561 aaccgatgat aggaattatt ctatttacaa ctttctttca ggttttcttt acacctggag
    16621 cgaccattct atgggagttt tggattttta aattatctgt agaagggttg caacaggcgg
    16681 cgattatttt tgttcgcttt gttttgatta ttttcttctc aaccctattg accttgacga
    16741 cgacacccct tagcttggct gatggtattg agtcggggct tgcacctttg aagaaattta
    16801 aagttcctgt gcatgaaatt ggtttgatgt tgtccatgag cttgcgtttt gtaccgacct
    16861 tgatggatga taccactcgg attatgaatg ctcagagagc tcgtggagtg gactttaatg
    16921 agggaaatct tattcagaag gtaaagtcag ttattcctat tttgattccg ttattcgcat
    16981 caagttttaa gagggcagat gctcttgcaa cggcgatgga ggcgcgtggg tatcaaggcg
    17041 gcgatgggag aaccaagtac cggattttgg aatggaagtt agcagatacg ttagcaattt
    17101 tagttatgtt agctttagcc ggactcttat ttatattgaa aaaataagta aaaaacgcta
    17161 gaaatagcgt ttttattgtc taatctcaat ttgtctgtaa tatttgtaac aatttcacaa
    17221 agtctaagta atagttagag ggtatgatag acacatgaca gaaaggaatg tgactattat
    17281 gaacattaca ttaaagaaaa acttaaaaac aactattgct ggtttggtag cgggaatctc
    17341 ccttttaact gcgggtgtag tcagtgcaga aacctatact gtaaagtctg gtgataccct
    17401 gtctgaaatt gctgaaacat acaatactac tgttgaaaaa ttagcagagc agaataagat
    17461 taccaactta gattttatcc atgtcggtca agttatcgaa ttgggtgatg tgacagtgaa
    17521 ggcagtagag agttcagttg aacaaactca atcaacatca acttctaccg caacagtaac
    17581 gactagcacc tattcttcaa atttgagtgc tgaagatgca gcagcaaaag aatggattgc
    17641 aatgaaggaa tcaagcggta gctatgatgc ccgtaacggt atctacattg gtcgttacca
    17701 gttgacaaat acttacttga atggtgatta ctcaccagaa aaccaagagc gtgtagcaga
    17761 tgcttatgtt gctagtcgct atggttcatg gtctgcagcc aaggctttct ggttggcaaa
    17821 tggttggtac taagataaat tagaagaggt ctagcacgat gctagacttt ttctgtctca
    17881 cgaatgtatt tcacaactgc tttttcgttc agtccaacgg tactgaatag tagcctctag
    17941 cccaaaactt ttgatttcca cgctgtatgg acataggtga tggaaaatat caattaagtc
    18001 ccgtctaatt ttttagtaaa tggattttct gcggtactta ggagtgacat acatttggta
    18061 tgtgataaac tgtaacggtt ttaaccatgc taaactagtc cactggacta gtttactcct
    18121 cctttattta acttgacaaa ttagattata acaggaaaaa aatagaagct caaagccttg
    18181 ctagccacca gcataggtag tagttttctt gtttttctct atgagaaaac tagcccgaag
    18241 ccataataag aaaaaggacc gttagggtcc tttttggttt acattattgt caatcttctc
    18301 caaaaatttc ttgagcaagg cgacgacccg tcggtgtagc tgcaaggcct ccttcggcag
    18361 tttcacggaa ggcggttggt agggcagatc ccacttggta catagcgttg atgacttcat
    18421 caacagggat ttttgattca attcctgcca gtgccatatc ggcagctacc atggcgtagc
    18481 ttgctcccat tgcattacgt ctgacacaag ggacttctac cagaccagcg acgggatcgc
    18541 aaatcagacc cagcatattt tttatgacaa agcagatggc ttggctggct tggtagggag
    18601 ttccacctgc tgccagtgtc agggctgcgg cagacatagc agaggcagat ccgacttctg
    18661 cctgacagcc tccttctgca cctgagatgg aggcgttgtt ggcgataact agtccaaagg
    18721 ctccagctgt aaataggaag tcaagttgct gttcttctgt caaattgagc ttttcaatag
    18781 caactcctag cacagctggt agacagcctg cagatcctgc tgtcggagtg gcacagacta
    18841 agcccatttt ggcattcaat tcattaacgg ccatggcatt tcttgcggcg gataggacag
    18901 cggaatctga caaggtttta ccagatttca tataggcatc taacttggca gcatcgcctc
    18961 ctgttaaacc agatacggat ttgctttcag taagtccatc tacgatggag gctttcataa
    19021 ctgtcaagtt tcttgacata attgtcaata tttcttcgcg gctacgaccg gtcaactcaa
    19081 tttcagtcgc gatcatgagt tcagctacat taccagaaaa gttgtctgct tgctgaacta
    19141 attcttcgat agtataaaac atgtctttct ctttctagtt gaagaaggtt acattgtgca
    19201 ggtgtggaat tttttcaatt tctgcaatag aattttcaca ttggcgagca tccacttcga
    19261 taatcataat ggctttttcg ccagcttttt cacgtgtcac gttcatttgg gcgatattga
    19321 tgtcatactt agaaagaaca tcggtcactt tcgcaatcat accagggaca tcttggtgaa
    19381 caataataat agttggcgta ttcatattta gattgacaga gaagccgttg agctctgtta
    19441 cttgaatgtt tcccccaccg atggaaacgc ctgtggctga gatggatttt ttatcgtttt
    19501 ttatgatgat tctggtggta ttgggatgtg gggtattgct gtccttgttg acacgccagt
    19561 aaaccttaat gcctcgttct cttgcaatat caagagagtc aggaatgcgg ggatcatccg
    19621 tatccatgcc cagaatacct gctaccaagg ctacatccgt accgtgacca cgataggtct
    19681 tggcaaagga attatagagt tgaaattcca cctctgtcgg ctcatcgccg aagatggaag
    19741 acacaatttt cccaattcgg accgccccag ctgtgtgact agaagatgga ccaatcataa
    19801 caggtccaat aatatcaaag accgactgaa attttaagtt tgtcatagta atcctcacgt
    19861 ttttcttggt actattatat caaattttcc agttagagaa tatgcctaga tgaatgtgtt
    19921 ttcttatgtt aaaattctat cgcttaccct ttttgtatgg tataatacaa gttgttcaaa
    19981 atcgtcaatc gtttttggat aatcaaattt tggaatacga ccttcaaatc gttatttcta
    20041 cgaaaagatg ggagaagatt atgtcaattg acaattctaa aacccgtgtt gttgtcggta
    20101 tgagtggcgg tgtggattca tcggttacgg ctctcttgct caaagagcag ggctacgatg
    20161 tgatcggcat cttcatgaaa aactgggacg acacggatga aaatggcttc tgtacagcaa
    20221 cagaagatta caaggatgtg gctgcagtgg cagatcaaat cggcattcct tactactctg
    20281 tcaactttga aaaagagtac tgggaccgcg tatttgagta ctttttagca gagtatcggg
    20341 ctggtcgcac gcccaatcca gatgtcatgt gtaacaagga aatcaagttc aaggctttct
    20401 tggattacgc tatgaacttg ggtgcggact atgtggcgac agggcactac gctcaggtta
    20461 cccgcgacga ggacggcacc gttcatatgc tgcgtggggc agataatggt aaggaccaga
    20521 cctatttcct tagccaactc tcacaggaac agctgcagaa aaccatgttt ccgctcggcc
    20581 atttacaaaa gcctcaggtg agggaaatag cagagcgagc aggcttggcg accgctaaaa
    20641 agaaagactc gacaggcatc tgctttatcg gtgaaaagaa cttcaaagaa tttttagggc
    20701 agtatttgcc agcccagccc ggtcggatga tgaccgttga cggtcgtgac atgggagagc
    20761 atacaggcct catgtactat acaatcggtc agcggggcgg gcttggtatc ggaggacaaa
    20821 tcggagggga caatgagcct tggtttgttg tcggaaaaga cctgtcaaaa aatatcctct
    20881 atgtcggtca aggcttctat catgagtcct tgatgtcaac ttctttacag gctagtcaag
    20941 ttcactttac acgtgatatg cctgaagaat tcacacttga gtgtacagct aagttccgct
    21001 accgtcaacc agacagtcaa gtgactgtca aggtaaaagg tgacaaggca gaagtcatct
    21061 ttgcagagcc acaacgggct atcacaccag gacaagccgt tgttttctat gacggacagg
    21121 aatgcctcgg tggcggcatg attgacatgg cctataaaga cggagaggct tgtcagtata
    21181 tttaatcaaa aataatagct tagcactctc gtgctaagct atttatctta tccccagaaa
    21241 gcatcttcgg ctttttggtc ggctgagaag agccaaactt ccttgatttt gccatcttcc
    21301 atacggaaaa gatcgatacc attcatgttt agttcttcac cgtctgtgcg agtaccgagg
    21361 aatgttacgt tagcggcaac aagagtatca ttatcggata cccagtttgt cactactttg
    21421 aaagttccat ttgttttttc ggcgaaagtt gctagatgtg ctccgagtac ttccttacca
    21481 attttagcac cagatgttga atgatttccg ggttgatgcc agataatgtc gtctgccatt
    21541 gtttcaaaaa gagctgcaaa atcaccagcg atgagagcat tgttataggc attaaaaatt
    21601 tctaagtttg ttgacatttg atgtcctcca atttttttga tatagtacaa ttatagtgga
    21661 agtagtcaat tatacaagta ggtacttttg tatttgttgg tatcaaaagt gatactattg
    21721 tgataaataa aggagaattt ttttgaacaa agttagtgaa tatggtattt gtccttttgc
    21781 aacaacgcaa aaagtcttga ctggtaagtg gggattggtg attatctacc aactcagtac
    21841 aggaacgaaa cgcttcaatg aattacagcg actaattcca ggtattactc aaaccatgtt
    21901 aacaaggcac cttagacaat tggaggagga tcgcattatt agtcgcacgg tctatgcaga
    21961 agtcccccct cgtgtagagt atagcttgac tgaaatgggc gaaaaatttc gttcggtgct
    22021 ggatgctgtt gaggcttggg gcttagaata tattgaaacg ttaacgtaac accagatttg
    22081 aaattctaca aatcttttgc taaaataagc gtaacaatta tcatgatggt caaagctcat
    22141 gggaattgta ggcttttttg tcctgcagtt ttcgagagtt ttggctattt tttgcgattg
    22201 gggagagaag atggatttca gaaccagagt tgacaaccaa attttcggtg tccgtgcgac
    22261 gggcttggtg gtacaagatg agaagttata tctcgttaag tcgcctgaag ggaaatacta
    22321 cactttgggt ggagctattc agcttggtga aacaaccgaa gaggctgtgc aacgggaaat
    22381 gaaagaagaa atcggaattg atgtggaggt tggaccacta gctttcatcg ttgaaaatca
    22441 gttcaccttg caggagaaat cctatcatca gattgaattt ctttatcttg ttaccccact
    22501 gtccgagcca gtcacctatc tggaagaagg aaattccatt cgccagtgtg aatggattgc
    22561 ttttgtggac ttagagaaat tggatctcaa tccagccttt cttaagaccg agctagccaa
    22621 atgggacgga caactaaagc attttatgaa caaagacaac taaagtagcg gaggaaacca
    22681 tgcctgttaa attgattgcc catgtcttgc tgactgttgc agacagtcac ttgatgattc
    22741 agcgttcgca gattaagcgt ggagagccga atgtatttcc gctgcattgg gatattccag
    22801 gcggtcgtgt cgaggagaat gagttgcccc gtgatgctgc agtgagagag tgttttgagg
    22861 aaacaggtat ttcgatagaa aaggaaaatc tgaccattat ccatgaagat agtcagtttg
    22921 atgaagaaaa acagacggtg tttacaaggc tggtttatga agtaacactt cctgaacaac
    22981 cgaaaaccat tcttcttgac ccagaagagc atacagattt tctatggtta gcccctagcg
    23041 ataaaaataa gaaaaactta gttccatatc tggacgaaat tttagaaaag agaaggataa
    23101 atggatttta ggaccagaat tgacaatcaa atcttcggtg tccgtgccac tgcattgatt
    23161 ataaaagatg ggaaaatatt tctcacgaag gacgctaagg gccgttatta tacgattggt
    23221 ggtgcggttg aggtcaatga ggtagcagcg gatgcggctg ttcgggaagt caaagaagaa
    23281 ttagggattg acagtcgtgt caatcaatta gtttttgtcg ttgaaaatca gtttacacat
    23341 gaaggtatag attttcacaa tatcgagttt cattttatcg ttgagcctat tggagaaatg
    23401 cctaaggaga tgattgaagg gaagttgaaa caaccgtgtg aatggattgc acttgacaac
    23461 cttgtcaact tagatgtcgt accagctttt ctgacacagg aattaccaaa ctggagtgga
    23521 caagttaaac atatcatgaa catgaaggag agaacaacat gacacacaca tttgcagaaa
    23581 actatgatgt catcgtgatt ggtgcggggc atgcgggtgt agaagcggga ttggcagcca
    23641 gtcggatggg ctgtaagacc ctgcttgcga ccattaactt ggatatggtg gcctttatgc
    23701 cttgtaatcc ctccattggt ggctctgcca aggggattgt ggtaagagaa atcgatgccc
    23761 tgggtggcga aatgggccgc aacattgaca agacctacat tcagatgaaa atgctcaata
    23821 tgggcaaggg gccagctgtt cgtgccttgc gggctcaggc agataaggca gagtatgcat
    23881 cagagatgaa gcggacggtg gagcgtcagg aaaatctgac cctgcgtcaa accatgattg
    23941 atgagatttt ggtggaggat ggcaaggtta tcggtgtccg cacggctacc aaccagaaat
    24001 tctcagccaa ggcagttgtg gtgacaacgg gtacagcctt gcgtggtgag attatcatcg
    24061 gtgacctcaa gtattcgtca gggcctaaca atagccttgc ctctatcacg ctggcggata
    24121 acctgaaaga acttggactt gagataggtc ggttcaagac aggaacgcca ccgcgtgtca
    24181 atgctcgtac cattaactac gaagacacgg agattcaacc aggcgatgaa aagccaaacc
    24241 acttttcatt cttgtccaag gacgaggact atttgctgga tcaaattcct tgctggttga
    24301 cctataccaa cgccaccagc cacgagatta tcaacagcaa tcttcatcga gcacctatgt
    24361 tttcaggaat tgtcaagggg attgggcccc gttattgtcc gtcaatcgag gacaagattg
    24421 tccgttttgc ggataaggaa cgccaccagc ttttcctaga gccagaaggt cgcaatacag
    24481 acgaaatcta tgttcaaggg ctgtcaacca gtctgccaga agatgtgcag caggacttga
    24541 tccactctat taaaggcttg gaaaatgccc agatgatgcg gacgggctat gctatcgagt
    24601 acgatatggt tatgccgcac cagttgcggg cgacgcttga aaccaagaag atttcagggc
    24661 tctttacagc aggtcagacc aacggaacat caggttatga agaagcagca ggtcagggaa
    24721 ttgtcgctgg tatcaatgca gccctcaagg tgcagggcaa gcctgagctg attttgaaac
    24781 gaagcgacgg ctacattggt gttatgattg atgacctggt aaccaaggga acggtggagc
    24841 cttaccgcct cttgaccagt cgggcagaat accgcttgat tctgcgtcat gacaatgctg
    24901 atatgcgact gacggagatt ggtcgtcagg ttggcttggt agatgatgaa cgctggcagg
    24961 tcttccagat tcacaaaaac caatttgaca atgaaatgaa gcgtttggag tctatcaaac
    25021 tcaagccaat caaggaaacc aacgaaaaag tcgtagccat gggcttcaag cccttgacag
    25081 acgctctgac tgccaaggaa ttcatgcgtc gtccagatgt gacttacgca gatgcggtag
    25141 cctttatcgg tcctgcggca gaggatttgg acgccaagac cattgaattg attgaaacag
    25201 aagtcaagta cgagggctac attgctaagg ccttagatca ggtggagaag atgaaacgta
    25261 tggaagaaaa acgcattcca gccgacattg actgggatga tattgactcc attgcgaccg
    25321 aggctcgcca aaaattcaag ctgatttcac cagaaaccat tggccaggct agtcggattt
    25381 ccggtgtcaa tccagcggat atatccattc tcatggtcta cttggaagga cgcagtcgtt
    25441 ccatttctaa aaataaatca aaggacagtc actaaggctg ttcttttcgc tgtatgtcag
    25501 ctatatgtca actactttaa aatcatgtga aaagtagctt ttttactgaa tttatggtag
    25561 aatggcaggc agaggttagt gatgaaaaga tttcgatttt cgacaattca ctttgtcatg
    25621 atatgtgtca ttttatttgg gttggtggct cttgtccacc gattttttcc aattggtgcc
    25681 agtacagttt ttgcgctact catcagccta ttggtgttga ttgcgctgtt tatttatcaa
    25741 aaacattctt atgaatttag tgagctagaa cagattgaat atctcaataa tcaggccaat
    25801 tctggtttga tgatgctctt ggataaaatg ccagtgggag ttatcaaagt tcgaccagat
    25861 agtaatcagg tagaatggtt taatcccttt gctgagctga tttttgctca agaaaatggt
    25921 gagtttgatc aaaaaaaact acgtgaaatt attgacgttg gtctggatga ggagcgaatt
    25981 tatgcaaact tttcaggcaa gagatacgct gttaacgttg attttgatca agggttattt
    26041 tacttttttg atgcgtcgac agagtattca gcgacaaata gtttgatcgg aagccgtcct
    26101 gttataggga ttatttcagt tgataactat gacgagcttg aggatgctgt aactgattct
    26161 caaattagcc aagtcaattc cttcttggct caatttgttt cagaattttg ccatgattac
    26221 ggtatctact accgacgcgg cacaatggat cgattctatt tctttacaga ttatgctgtg
    26281 ttggaaaaat tgatagagaa taagttttca gttattgata agttccgcga ggaggctaaa
    26341 aagttagatt taggtttgac tttgagtatg ggattggcgt atggtaatga aaatcatcac
    26401 caaatcggac aggttgcgct ccaaaatctc aatatggctg aggttcgtgg tggagaccag
    26461 gttgtggtca aggaaaatga tgagagtaaa cagccacttt tctttggcgg tggctcggct
    26521 tcttccgtta aacgaacacg tacgcggact cgtgctatga tgactgctgt atcagataaa
    26581 ctcaaatcgg ttgatgctgt ttttgtggtg ggacatcgta atttagatat ggacgcgctt
    26641 ggatccgcgg tcggcatgca gtactttgct caaaatatta tgaacaatgc ttatacggtg
    26701 tataatccag atgaaatggc accagatatt gcacgtgcta tcaagaagtt gagtgatgaa
    26761 aattgttcta atttgttaac ggttgaggaa gccatgaaga tggtcacttt ccagtcgttg
    26821 ttaatcatgg tagatcattc aaagattggc ttgactttgg ataaggattt ctatgaaaaa
    26881 tttacccagg ttgtggtggt tgatcatcat cgtcgcgata cagatttccc aaataatgca
    26941 gttttgactt atatagagag tggtgctagt tctgcgagtg agttagtaac ggaattaatt
    27001 cagttccaga atgacaaaca ccataagctt aatcgcattc aatctagttt attgatggct
    27061 gggattatgc ttgatacaaa aaatttcacc tctcgtgtga ctagtcgtac ttttgatgtg
    27121 gctagttact tgcggactcg tggtagcgat agcttggaaa tccagcagat tgctgcgaca
    27181 gattttgagg aatatcgtca aatcaatgaa ctgattttaa gtgggcagag aattgagtcc
    27241 aatgttgtta ttgcgtgtgc agatgatact aaagaatacg ataatattat tccgagtaag
    27301 gctgccaata caatattgga catggcagga attgaggcgg tattcgttgt aacaagaaat
    27361 atcaaagggt atgtatctat ttctgcaagg agtcataata aaatcaatgt tcaacgcatc
    27421 atggaagaaa tgggtggagg tggccacttt aacctagctg ccgctcaggt atatgaccag
    27481 acaatcgcag aagtatgtga aaagttgacg gataaaatcc gcgaagaaat aaatggaaat
    27541 taggagaaca gatatgaaag taatcttttt agcagatgtt aaaggtcaag gtaaaaaggg
    27601 tgagattaag gaagttccaa caggttacgc ccaaaatttc ttgatcaaga aaaatttggc
    27661 taaggaagca acaaaccaag caatcagcgc ccttcgtggt caggaaaaat ctaaggaaaa
    27721 ggctcatgca gagatgattg cagaagcaga ggctatcaag gctaagttgg ctgaggaagc
    27781 tactttagtg aaatttgtcg aaaaagttgg tccagatggt cgtacctttg gttctattac
    27841 cagcaagaaa attgctgaag aattggacaa gcaatttggc atcaagattg ataaacgcca
    27901 tattcagctg gatcacccaa ttcgtgcgat tggtctcatt gatgtaccag ttaaaatcta
    27961 tcaagatgta acaggcatca ttaatttgag tattaaggaa gcttaattat ttatctagcc
    28021 agtgaggagg tgagatcttg gcagagttgg atgaattgcg ggtgcaaccg caggatattc
    28081 tagctgaaca atcggtatta ggagctattt tccttgatga aggcaagctg gtcttcgttc
    28141 gtgaatacat cgaagctgaa gattttttca aacatgctca taagctaatt tttaaagcta
    28201 tgattgctct ttctgataga aatgaggcaa ttgatgcgac taccatgcgt aactatttag
    28261 tgaaccatgg tgatttggaa aatatcggtg gtttggccta tttggctgaa atcattagtt
    28321 ccgtaccgac ggcagccaat gcggaattct atgccaagat tgttgctgaa aagtctaatc
    28381 tccgtaaact gattgcccgt ttgacggatg cagttaatca ggcttatgag ggtacggatg
    28441 gttcagatga cattattgcc aatgctgaaa aagctttgat tgatgtcagt gagggagcca
    28501 gtcgaagtgg tttcaagcgg attgatgatg tcttgaatat caactttgac aaccttgaaa
    28561 ctcgtgctaa gcagacgtcg gatattacag ggattgcaac tggctatcct gctcttgatg
    28621 ccatgacaac gggtctgcat gaggaagagt tgattattct tgcggctcgt cctgcggttg
    28681 gtaagacggc ttttgccctc aatattgctc aaaatatcgg tacaaaactg ggtttgacag
    28741 ttgctatctt ctctttggag atgggtgcag aaagcttggt tgaccgtatg ctcgcttctg
    28801 agggagttat caattcgagg gctatccgta cgggtcacct aacgcaagag gaatggaaca
    28861 agtatatggt ggctcaagct aatttggctc gagcaagtat ctatattgat gatactccag
    28921 gtatcaagat taccgaaatt cgctcgcgtt ctcgtaaatt ggcgcaggag acagggaatt
    28981 taggtttgat tttgattgac tatctccaat tgattacagg aaccggtcga gaaaaccgtc
    29041 aacaagaagt ttcagagatt tctcgacaat tgaaaattct agccaaggaa ttaaaagttc
    29101 cagttattgc tctaagccag ttgtctcgtg gtgtggagca acgtcaagat aaacgtcctg
    29161 tcttgtctga tatccgtgag tcagggtcta ttgagcagga tgcggatatc gttgccttct
    29221 tgtatcgtga tgattattat gaacgaggag agcaagaaga cggtggtatt cccaataata
    29281 cggttgaagt tatcatcgag aaaaaccgtt ccggtgcgcg tggtaccgtg gaactcatgt
    29341 tccaaaaaga atacaataaa tttgcaagta tttccaagag ggaggatgga tagagaatga
    29401 gtgatgcatt tacagatgtt gctaagatga agcaaatcaa acaagatatt aaggaccatg
    29461 agggacagat tgtcgagttg acccttgaaa atggtcgtaa gcgtgagaag aataagcagg
    29521 ggcgtattgt agaggtttat cagtctctct tcatcgttga atttgaagat ccaaacaata
    29581 cctttgtgga atcttatact tactcagaca ttttgactga aaagattttg attcattatt
    29641 tggattaatc gctatataag gctttacaga gccttttttt tgtgctatac taatctttgt
    29701 gtgaaataac agcagggcaa aatgaagctc gtcaacagaa ggtcagcaag aagagtaatc
    29761 gttgctgttt cgatgaaggc ctcctgcacg aatcaggttt gcttaaaacg ttatttccta
    29821 cagataagtc tttttgtttc cttttagtac taggcaagga ggtgcaggct atactgaggt
    29881 atgccaagcc gacttaacga cgtaataaaa gagaaacgaa atgacggaaa tttttatttt
    29941 aggaggacat aacttatgtc acgttataca ggaccatctt ggaaacaagc tcgtcgtctt
    30001 ggcttgtcat tgacaggtac aggtaaagaa ttggcacgtc gtaactacgt accaggtcaa
    30061 cacggaccaa acaaccgttc taaattgtca gaatacggtt tgcaattggc tgagaaacaa
    30121 aaattgcgtt tctcttacgg tttgggtgaa aaacaattcc gtaacttgtt cgtacaagct
    30181 actaaaatca aacaaggtac tcttggtttc aacttcatgc ttcttttgga gcgtcgtttg
    30241 gacaacgttg tttaccgtct tggtttggca actactcgtc gtcaagcacg tcaattcgta
    30301 aaccacggtc atatccttgt tgacggcaaa cgcgttgaca tcccttcata ccgtgttgaa
    30361 gttggtcaag tgatctcagt tcgtgagaag tcaatcaaag ttccagctat ccttgaagct
    30421 gttgaagcaa ctcttggacg tccagctttc gtatcattcg atgctgaaaa gcttgaaggt
    30481 tcattgactc gcttgccaga acgcgacgaa atcaacccag aaatcaacga agctcttgtc
    30541 gtagaattct acaacaaaat gctctaagat ttgtatcgat attttaaaag ccctatttac
    30601 aagggctttt tgtctgtatt tgaggaggga ttatgtggcg taagtatttt ttgctagtgc
    30661 tattagctat tttggtcgta ggtggggcct tctttctatc tcaatcagcg gctacgccaa
    30721 atgaatcaga ctatgtgaag gctgtaaaga gttaccaggc tatttcgata gacgaagtgg
    30781 agcaaaaggt ccaagacgag gaagaattta tattatacat aggtcgtgag acatgccctt
    30841 attgtcgtga ttttgttccg aaattaacag aggcagtaga gcaatcacat gcgacgatct
    30901 actatttaga tagcgagtcg gatccgaatg gaaaaataca acaatttcga cagagtcaag
    30961 gtcttgctac ggttcctagc ttaacctact ataaatcagg taaattatct ggaatactcc
    31021 gtaaagggag ccaagcaacg ctatccgaaa tagagaattt tttagctctt caagggcagt
    31081 aaatagtttt aagaatgtat gaagcggata tcatacattt ttttgttcat gtttgtgaaa
    31141 atatttcaaa acaaattgaa aaacatttca caatcttgta taatactaat accagataaa
    31201 aattggaggt ttatatgaaa aagaaagctt ggttaggctt attaatgagt ctacttgctg
    31261 ttttgttttt agtggcgtgt ggaggtaagt ctgaaaagac agctacatct tcatcatcta
    31321 cgacttcttc ttcatcagaa gaagctgttt caggtgcatc tgagaaagtt tatacagatc
    31381 catctgagtt gaaagatagc tacgatgtta tcgttgttgg ttcaggtggt gcaggtatgt
    31441 cagcagctat ctcagctaaa gacgctggtg ctagtgttgc tctcttggag aaaatgcctg
    31501 ttatcggtgg taatacggct aaatcatcag ctggtatgaa tgcttcacag actaaattcc
    31561 aagaagcgga aggtattgct gatacaaatg ataaattcta cgaagaaacg cttaaaggtg
    31621 gtaaagggac aaacgatcct gaattgcttc gttatcttgt agataactct gctagtgcaa
    31681 ttgactggtt ggatggaatg gggatcactc ttagcaacct aactacaact ggtggtatga
    31741 gcgagaaacg tacccaccgt ccagcagatg gttcagctgt cggtggctac ttggtaaatg
    31801 gtctttacca caatcttgtt gaacgtgaag taccaatttt tgtcaatgca gatgttacaa
    31861 aactccaaga caaggatgga gctgtgacag gtgttgaagt gaagattgct ggtgaaacta
    31921 agaaaatctc agctaaagca gttgtattgg cgactggtgg tttcggtgct gatttggaaa
    31981 tggttgctaa attaaaccca gcattgaaag gttatgttac aactaaccaa gaaggatcaa
    32041 caggtgacgg tattgcgctt gctgaatcag aaggtgcagc aactgttgat atggaacaaa
    32101 tccaaattca cccaagtgtt gagcaagaaa cttcttactt gattacagaa gcagttcgtg
    32161 gcgaaggtgc tatccttgtc aactcaaaag gtgagcgttt tgttaacgaa ttggaaactc
    32221 gtgataaagt ttctgcggct atcaatagtt tggatccaaa ctatgcttat gttatctttg
    32281 atgatgcctt gaaagatcgt gtgaaggcta ttgctcaata tgaagaaaaa ggtcttgtaa
    32341 aaacgggtgc tactcttgca gatttggcta aagaaattgg tgtacctgcg gatgctcttc
    32401 aaacaacact tgatacttgg aacaaggctg tggcagacaa aaatgatgcg gcatttggtc
    32461 gtacatcagg tatggaccat gctttgaata ctggttctta ccatgccatt aaagttgcac
    32521 ctggtgttca ccatacaatg ggtggtgtga aaatcaatac caatactgaa gtattgaaaa
    32581 cagacggttc agcaatttct ggtctttatg ctgctggtga agtaactggt ggtgttcatg
    32641 gtcaaaaccg tattggtggt aatgcagcag cagacatcat cgtatttggt cgtcaggctg
    32701 gtgaacaagc agctggattt gctaagaaat aaattgtaga cataagaggc tcggcagaaa
    32761 gaaggtcgag cttctttttc ttgtccctct atctctaaga tgatatactt ttaaggtatg
    32821 aagaagaaaa tagtattatt attaggagct attgcagtta tagttttgac ttggtcggct
    32881 attactggcc agcgtcagca atcctatgcc gaggctgagt taagagacca ggataaaatc
    32941 tggattatca ctgatttgca ttatttgtca caggatttat ttgatgatgg agaggctttt
    33001 tcctatatag aaaaaacagc tgctggtaag gatttacgtt atggaaaaga gcggatggag
    33061 gctttggttg agcaggttga gcgtgagcaa ccgtccttat tactagtcag tggggatttg
    33121 actctaaacg gtgaaaaaca gagcatggtt gagttggcgc aatattttac ccggattgaa
    33181 gaaaaaggaa cggaggtttt ggtgattcct ggcaaccatg atattgccag tggatgggct
    33241 agagccttta agggagacca gcagatagtg acggatcagg tcactgctca gcaatttgca
    33301 gagctatttg tcaatcacgg ttatcaacaa gctagcagtc gtgacaaagc ctcattgagc
    33361 tacctggcca aaccattttc caatgcttgg tttctgatga tagacagcaa catctactct
    33421 gacggctacg gaaaaggagc tcctccaacc aatggatgta tcaaaaaaga gaccctagaa
    33481 tggatagaag ttcagcttca ggcagccaag gaagctggag tgagcctgtt acctgttgtc
    33541 catcacaatg tcttgcaaca gcatgccatg ctctcaaaag gctatacttt ggataatgct
    33601 gccgatttga aggctttgtt tgatcagtat gggattcatt ttggtttttc aggccatact
    33661 cattctcaga atattgttaa ggaagacttg ggacaagtta actatactga agtggtcaat
    33721 ggagcatttt ctatttatcc agctattatc ggtcaattga gccttgatga tacaagcatt
    33781 cactatcaaa aaactcaact tgatatggct tcgtgggcag aaaagcacca acctagtgat
    33841 ccaaatttgc aggatcacgt tacctactta caaactgtct ttgacaatac cagtgacatc
    33901 atggtccaca atgtgttgaa cgatgagcgt tggtatgacg gcgagacggc agacgctatt
    33961 tcacaattta tcatgccggc caaccgtgct tatttttcag gagaaaaact agatcagact
    34021 tggctagatg agaaggtatt tccaagccag gcttatcaga ccttgcaagc agcatcaccg
    34081 agaagtttct tggctgatta tcttgatgtg attataaaac ggagtcaaag tcgagatgtg
    34141 gagcaagtaa cggtttctaa atgatgaata gaaagaaaat cccgccttca agcgggattt
    34201 ttctatactt gtaaagggag aatgatcttt agttgaaccc aattatcttc cttgctaagt
    34261 gtgagactgc caccgtattt attggcaaca tactccatac tcttaagacc gaatccgtgg
    34321 tagtccttat ttgtttttga tgtttctggg agctgtcctg tggataagtc aagcgaagaa
    34381 gtatcgtagt tgtctaatcg gatgatgaga aattgctgat ggctggcaac ctttaaagta
    34441 atcaagcgtt gttcaggatt gtctattttt tccacagcct cgatggcatt gtcaatggca
    34501 tttccaaaca gagctgaaat atccattaca tccataaaat ggaggggttc tccctgaaca
    34561 atacaggtaa agttgattcc attttgcaaa cagtaataat ttttctggct gagaatggta
    34621 tctagaacgg gatttcctgt ttcaatcttg gcatcaagtg tctggatcac ctcgctcatt
    34681 tcctctaggt attgctcctt tttggtttta tccgattctt gctgaatgat ggccagttga
    34741 tgctttaaat catggacctt acggtcaaga atctcactgt tttcacgata ggcttggtat
    34801 tgcttgtatt gaagttgaaa gatattattg atagaagtca attcctgccg taaatagcga
    34861 tcgtattgtt gagattcttg ggtgaatagg agtagaagac cagagagatt gacggttgtc
    34921 cggagaatga agatgctggt cgaatcttga aattggcgcg tgcctgagag gatgaaacca
    34981 atattactga gaacaaagat agataaagtt gtaaagacgg ctaccgtcac atctcgctgc
    35041 tcaatgaatt tatccaattc ttctaagcga actttttgat cttgaagata gatgagccaa
    35101 taggaaagta gagaagttat caacagaaat aacccctgtg tccacaagtt atccacaggt
    35161 tgttgataaa tcgtcaaaca gtagagatgc caagtaatgg aggctactaa ttcggcaata
    35221 ataaaggctt ttgctgtcaa atagagacta gtcctcttgt ggataactcc aagaaatcga
    35281 acggaaacaa acatccaagc gatattggtg cccattccta cagtccaaag gagcaagggg
    35341 agtttgccag ccgctagttg aagtaagatt tgtatgagaa aaatcaggag gatacgtacc
    35401 tgtttgcgtg accatttttc agacaaaaca agtgaggaac ataccagtag gcaggccaag
    35461 ctttctgtta gtgcagtata gaaacgtgga atatcaggga aattgatcat agtaggctat
    35521 ctccgatgaa gttggttaga gctgtcataa attctttttt ccttgggcgg ctaatcggca
    35581 aggctgtatt tgtgacgtaa acaaggctac cttccacttt ttgaacatgg gacaaattga
    35641 tgatataggc cgagtgggct cgtacaaaca atttactgtt taacatggct tcgagatttt
    35701 tgagactatt atgggtaatg gttaggccac tgtcaactgt gtagatgtga acctgatgtc
    35761 cttgactttc taggtaaaca atatcttctt gatagagttt tacggtggac tgcttgcttt
    35821 ttatatacaa actttgcttc tcttggctat cgggtaattt tctaagaatt tttttaaaat
    35881 gttcctcaaa gacaaaggag ctcagtggtt tgagaagaaa atcaatggcc tcaacagagt
    35941 agccctgaat agcgacatgg gaatgattgg tcacaaatac taatagaact tccttatcaa
    36001 gatttcgaat tttttgagcg gtggtcatcc cgtccataat ctccatctcg acatctaggt
    36061 aaatcaggtc aaattgtttt tgatagtcac tagtgatatg gagaccgtcg ttaaaacagc
    36121 tgatttccac tgcaatccca gcttttttgc agtaggtttt gatgtagttg gacaatctat
    36181 cttgctcaat tttttgatct tctacaatcg cgattttcat aaagcac
//
LOCUS       DBNFCO010000010        35502 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.010, whole genome shotgun sequence.
ACCESSION   DBNFCO010000010 DBNFCO010000000
VERSION     DBNFCO010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 35502)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35502)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35502
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.010"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            325..1818
                     /gene="sly"
                     /locus_tag="AC1PIV_000437"
     CDS             325..1818
                     /gene="sly"
                     /locus_tag="AC1PIV_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin suilysin"
                     /protein_id="HIP6611487.1"
                     /translation="MRKSSHLILSSIVSLALVGVTPLSVLADSKQDINQYFQSLTYEP
                     QEILTNEGEYIDNPPATTGMLENGRFVVLRREKKNITNNSADIAVIDAKAANIYPGAL
                     LRADQNLLDNNPTLISIARGDLTLSLNLPGLANGDSHTVVNSPTRSTVRTGVNNLLSK
                     WNNTYAGEYGNTQAELQYDETMAYSMSQLKTKFGTSFEKIAVPLDINFDAVNSGEKQV
                     QIVNFKQIYYTVSVDEPESPSKLFAEGTTVEDLKRNGITDEVPPVYVSSVSYGRSMFI
                     KLETSSRSTQVQAAFKAAIKGVDISGNAEYQDILKNTSFSAYIFGGDAGSAATVVSGN
                     IETLKKIIEEGARYGKLNPGVPISYSTNFVKDNRPAQILSNSEYIETTSTVHNSSALT
                     LDHSGAYVAKYNITWEEVSYNEAGEEVWEPKAWDKNGVNLTSHWSETIQIPGNARNLH
                     VNIQECTGLAWEWWRTVYDKDLPLVGQRKITIWGTTLYPQYADEVIE"
     gene            2129..2830
                     /locus_tag="AC1PIV_000438"
     CDS             2129..2830
                     /locus_tag="AC1PIV_000438"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047465 - N-acylglucosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HIP6611488.1"
                     /translation="MGTISKTDLKQQIKDGIIVSCQALPGEPLYREEGGIMPLLVKAA
                     QEAGAVGIRANSVRDIKEIKEVTTLPIIGIIKRDYPPQEPFITATMREVDELAALDIE
                     VIALDCTKRERYDGLDIVDFIKQIKEKYPEQLFMADISTFEEGLTAYEAGIDFIGTTL
                     SGYTSYSRQEEGPDIELVDRLCRAGIDVIAEGKIHYPDQVKIIHDLGVAGIVVGGAIT
                     RPKEIAERFISALHK"
     gene            2858..4366
                     /locus_tag="AC1PIV_000439"
     CDS             2858..4366
                     /locus_tag="AC1PIV_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HIP6611489.1"
                     /translation="MNFKKFSQLGQAFMLPISILPVAGLLLGIGGALSNSNAVAQFPV
                     LDQAWLQAVFTIMSTAGSAVFANLALIFAIGVAVGLADADKGTAGLSAGVAYLVYTAT
                     ISGFLTLFADKGASIDTGVLGALAIGITVATLHNKYRKIELPAFLGFFGGSRFIPIIS
                     SFAAIAIGSIFYIIWPPIQNLLVDFGKAIAEMGSFGTFLYGFGLRLTGAFGLHHTIYP
                     MFWYTSLGGSEVVAGETIQGAQNIFFAQLADANHTGLFTYGTRFFAGRFATMIFGLPA
                     SCLAMYHAIPKENRKKVGSFYSSSALTSLLTGITEPIEFSFLFVAPWLYVVHAFLDGL
                     SFLVADLLQIRIGNSFSGGLIDYLIFGVFQGNDKTNWIYVIPVGLLWAAVYYLVFKFL
                     VTKFHVLVPGMESSDQASHSEKVLSNGSSLRDNAIAIIDALGGADNIENVTACATRLR
                     VSLRNSGLVDKGVIQSIGATAVLDVKGGIQAIFGGKAILYSQEINQILGLEE"
     gene            complement(4470..5282)
                     /locus_tag="AC1PIV_000440"
     CDS             complement(4470..5282)
                     /locus_tag="AC1PIV_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HIP6611490.1"
                     /translation="MLQTPKHITAIIESHLDQMTRLEKQIASYFTQLDPSSADLSQEN
                     TIQQLHISPSALTRFAKKCGFSGYREFVFAFQNNQQYLDKHFEKLQRSLTKKVLVDYE
                     EILTATNKLVDEEKLEEIAKLIDSSKRVYFYGIGSSGLVAMEIKSRFMRLGVVCDAIT
                     DENNLIWTTNILDDSCLVIGLSLSGQTEEVMEHLQLAAQKGIPTALLTTRSFPHPTFD
                     QIIPVASVRHLNYGNRISPQIPLLIMLDIIYAYFLAIDKEKKENIFKQTIRE"
     gene            5382..5879
                     /gene="ybeY"
                     /locus_tag="AC1PIV_000441"
     CDS             5382..5879
                     /gene="ybeY"
                     /locus_tag="AC1PIV_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HIP6611491.1"
                     /translation="MYIEMIDETGQVSAQMQEQITELLQFAAEKIGKQNKEMAVTFVD
                     NKRVHEVNLEYRGIDRPTDVVSLEYKPESEIVFDEEDLLDNPELAEMMEDFDAYIGEL
                     YISIDKAREQAEDYGHSYEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRE"
     gene            5860..6261
                     /locus_tag="AC1PIV_000442"
     CDS             5860..6261
                     /locus_tag="AC1PIV_000442"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HIP6611492.1"
                     /translation="MDLQENNSKNRWKNRELIASLEFAVTGLLTAFKEERNMKKHLAS
                     AVLVVLAGLIFQVSVTEWLFLLLSISLVIAFEIVNSAIENVVDLASDYHFSMLAKNAK
                     DMAAGAVLFVSGFALLTGLIIFVPKIWDFIF"
     gene            6278..7177
                     /gene="era"
                     /locus_tag="AC1PIV_000443"
     CDS             6278..7177
                     /gene="era"
                     /locus_tag="AC1PIV_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HIP6611493.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNYVMGQKIAIMSDKAQTTRNKI
                     MGIYTTEEEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEKRGKGD
                     DMIMERLKQAKVPVILVVNKIDKVHPDQLLEQIDDFRQQMDFKEIVPISATQGNNVNR
                     LMEILKENLDEGFQYFPADQITDHPERFLVSEMIREKVLHLTREEIPHSVAVVIESMK
                     RDEFTDKVHIRATIMVERDSQKGIIIGKQGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEKEY"
     gene            7790..8617
                     /gene="mutM"
                     /locus_tag="AC1PIV_000444"
     CDS             7790..8617
                     /gene="mutM"
                     /locus_tag="AC1PIV_000444"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009910298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HIP6611494.1"
                     /translation="MPELPEVETVRRGLNRLVKGKVISKVEVTYAPMIKTGVDAFCQD
                     LIGQEILDVDRRGKYLLIYLTDHVLISHLRMEGKYNFFADQVPANKHFHAFFTFIDGS
                     TLVYQDVRKFGTMELLGKADVDAYFISRKIGPEPTEEDFDLEEFAKKLAKSKKPIKSH
                     LLDQSLVAGLGNIYVDEVLFKAKVHPAQTSNQLSTDQVADLRQATIEVLQLGIEKGGS
                     TIRTYKNALGMDGTMQDYLQVYGKTGQACPRCQTEIVKIQLGGRGTHFCPKCQVKHG"
     gene            8610..9212
                     /gene="coaE"
                     /locus_tag="AC1PIV_000445"
     CDS             8610..9212
                     /gene="coaE"
                     /locus_tag="AC1PIV_000445"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637643.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HIP6611495.1"
                     /translation="MAKIIGLTGGIASGKSTVTAFLREQGYPVIDADAVVHELQAKGG
                     KLYQILLKEFGPDILSADGHLDRVKLGQAVFADSKLRARLSDLQDQIIRQELLDRRDA
                     LKQTEQVLFMDIPLLYEADYSGEVNEIWLVYVDRAQQLERLMKRNGLAVQDAENRLAA
                     QLSLEEKRSQAQVVIDNSGAVEATLAQVAQLLEELKDGRR"
     gene            9199..10404
                     /locus_tag="AC1PIV_000446"
     CDS             9199..10404
                     /locus_tag="AC1PIV_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HIP6611496.1"
                     /translation="MDDGSSYWKQNLKVAWLGNFLTGTSFTLVMPFISVFVEELGVGP
                     GQVEYYAGLAVSVNALAAALMAPIWGSLADRYGRKPMMVRAAFAMIFTMGGMAFVPNV
                     FWLLTLRVLNGVFTGYIPNATALIASQVPKDKTGYALGTLSTGAVAGNLIGPTLGGIL
                     AEMFGVHMVFLLVGLLYAIVVLLTVFYIREDFVPVKKGEEMSVKEVFEQVKDRQMLVG
                     LFVTSMIIIAAAQAVVPILTLYVRHLGQTDNLLFVAGFIISLPGMASLVTSGYLGKIG
                     DRIGNHRLLLIALTYSLLINVFCVFAENPFQLGLLRFMYGFGTGALLPSVNSLLTKLT
                     PKEGISRIFSYNQLFNNLGSVVGPMMGSAVAAHMGYDWVFYLSSGLVLFNLIWSLTNF
                     RNYLKVRDV"
     gene            10404..10553
                     /gene="rpmG"
                     /locus_tag="AC1PIV_000447"
     CDS             10404..10553
                     /gene="rpmG"
                     /locus_tag="AC1PIV_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HIP6611497.1"
                     /translation="MRVKINLQCSECGSKNYLTSKNAKTHPDKIEVLKYCPKERKVTL
                     HLETK"
     gene            10600..10833
                     /gene="secG"
                     /locus_tag="AC1PIV_000448"
     CDS             10600..10833
                     /gene="secG"
                     /locus_tag="AC1PIV_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015136 - sialic acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015739 - sialic acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HIP6611498.1"
                     /translation="MYQALLAILLILSVILIVVIFIQPAKNQSSNVFDSSSGALFERT
                     KARGFEAVMQRITAILIFLWMLDALALVIISSK"
     gene            11265..13634
                     /gene="rnr"
                     /locus_tag="AC1PIV_000449"
     CDS             11265..13634
                     /gene="rnr"
                     /locus_tag="AC1PIV_000449"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HIP6611499.1"
                     /translation="MKNEIINYIKEVGPVTMDQLADQFGASSAKSFTDLVKLVSSMEG
                     SRQLVFDNAGRITLPAPKISKNKVTLQGIFRAHKSGFGFVTIDEEEDDLFVSRDDVNF
                     AIEGDRVEVAIKKVADRFKGTAAEAEVIDILEHSLKTAVGLIVFDEDKPEYAGYIKSK
                     NQKIAQKIYIKKSPLVLTGTEILKVDIEAYPNKKRDHFVATIRDVVGHKDDVGIDVLE
                     VLESMDIVSEFPDEVLAEANRVPESPSEKDFEGRLDLRDEIIFTIDGADAKDLDDAVH
                     IKQLKNGNLELGVHIADVSYYVTEGSALDQEAVKRGTSVYVTDRVVPMLPERLSNGIC
                     SLNPNVDRLTQSAIMEIDCKGKVVKHWIGQTVIKTTFRMTYSDVNDMIAGNKEKLDKY
                     KTIVPSVELMVKLHETLETMRYKRGALNFDTAEAKIIVNKDGLPVDIQLRQRGIAERM
                     IESFMLAANECVAEHFAKLDLPFIYRIHEEPKSDKLQKFIDYATSFGLTVYGTASSIS
                     QDALQDLMERVKDEPYADVLNMMLLRSMQQARYSEHNHGHYGLGAEFYTHFTSPIRRY
                     PDLLVHRMVREYGHNPSEKAEHFEQVIPELAKSSSSLERRAIDAEREVEAMKKAEFMQ
                     EFVGQEFDGVVSSVVKFGLFVELPNTVEGLIHVTNLNEYYQFHERTLTLQGEKSGRVF
                     RVGQPIRIKLTRADKMTGEIDFAHMPSELDIVEKALKAKRRTASHSNRDRDDRSGRGR
                     GKHYKQEAAGRDSGRHKSGKDHKSKSGKKDKKKKPFYKEVAKKNKKKRR"
     gene            13637..14104
                     /gene="smpB"
                     /locus_tag="AC1PIV_000450"
     CDS             13637..14104
                     /gene="smpB"
                     /locus_tag="AC1PIV_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HIP6611500.1"
                     /translation="MAKGEGNVIAQNKKARHDYTIVDTVEAGMVLTGTEIKSIRAGRI
                     NLKDGFAQIKQGEAWLVNVHIAPYDEGNIWNQEPTRTRKLLLRKKQIESLDNEVKGTG
                     MTLVPLKVYIKDGFAKVLIGLAKGKHDYDKRESIKRREQDRDIKRTMKAINSR"
     gene            complement(14191..15234)
                     /locus_tag="AC1PIV_000451"
     CDS             complement(14191..15234)
                     /locus_tag="AC1PIV_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HIP6611501.1"
                     /translation="MKAAIYEKAGKMTVAEIEKPSLQAKDDVIIKVVRACVCGSDLWG
                     YGEDIHHDHGDTNSGHEAIGIVEEVGEDITTLVPGDFVIVPFTHGCGHCDACRAGFDG
                     TCDNHPGYTNWGNNYQSQYIRFHYGNWALVKIPGQPSDYSEGMIKSLLTLADVMPTGY
                     HATRVADVKPGDKVVVIGDGAVGQCAVIAAKMRGASQIIMMSRHADRQQMALESGATA
                     VVAERGEEGIAKVREILGGGADAALECVGTEASIDQALGVLHNGGRIGFVGVPHYNNH
                     ALGSTFAQNIIIGGGSASVTTYDKEILLDAVLKGDINPGRVFTQTYSLDNIDQAYKDM
                     ANRKTIKAMITVD"
     gene            15403..16263
                     /gene="tehB"
                     /locus_tag="AC1PIV_000452"
     CDS             15403..16263
                     /gene="tehB"
                     /locus_tag="AC1PIV_000452"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0046690 - response to tellurium ion
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HIP6611502.1"
                     /translation="MTVLVPYKRMPIWNQDTVPQHFLTKHNTKVGTWAKIKVLRGQLK
                     FEPISDDNEILGEFVYGPTDDVPFVEPQAWHRVTLLTEDTEFFLEFFCQPEDYFAKKY
                     DYTRTHSEVLEALKRIEPCKVLDLGCGHGRNSLYLAQQGFEVTAVDKDVPSIRTLLQV
                     KEVEDLDLQAGTYDINSASLEQDYDWIISTVVFMFLERERVPAIIRNMQEQTRPGGYN
                     LIVAAMDTEDAPCPMNFSFTFGVGELKEYYRDWELVKYNEDFGQLHKRDENGHFLKMR
                     FATMLARKKG"
     gene            16457..18280
                     /locus_tag="AC1PIV_000453"
     CDS             16457..18280
                     /locus_tag="AC1PIV_000453"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016805 - dipeptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C69 family dipeptidase"
                     /protein_id="HIP6611503.1"
                     /translation="MKKTFVRIATFLMLVCLFPVQLVQACSGFIIGKGLTTDGSILYG
                     RTEDYPYPPNNGAHNKNYIVVPATAYAKGDMLVDESFGFTAPHLANEFKYTSTPDAAR
                     GDGSNGNFGAHGFNEKGVSMTATVTAIPNKKVLAVDPLVTAGGLGEAILIDYVLPRVT
                     SAREGIELIAKTIDEKGSAEGNIIVIADKNEVWYMEILSGHQYVAIKFPEDKYAIFAN
                     TYYLGHVDFTDTENVIASAKVEEVAKQAENYMMVDGKFHIAKSYGPENYADGDRSRTY
                     AGIKLLDPASSVTYEDAVYDLLRQPTDPSRRFSLQDTFALQRNRFEHLPEFRPDDEAG
                     KVKQGDNGANDQAADATYKYALGNENVIDAHVYQINSSLPSAFGGTVWLGLAQTRNTP
                     YVPFYGIVTDTYEAFKNRSASYDTNSWYWTVQNIDKMAISHPELFGTSIQEKWIALEK
                     EWIASQAALDAQYAGLSEDAAVALAPTVTEATLARSAEIFAQLKAVEAEMMAKIEAAT
                     TPSSSSTEPSTSTEPSSSGTETSTSTSQSTSDSNTGGATDTSSSSRTVVPSDKKVTPT
                     NKKGKSSLPSTGEQVSLLLVALGVAGILTAIFLHRKKSSKE"
     gene            18611..21100
                     /locus_tag="AC1PIV_000454"
     CDS             18611..21100
                     /locus_tag="AC1PIV_000454"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0140358 - P-type transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HIP6611504.1"
                     /translation="MKQASYPIQGMTCASCALTVEKAVGKLAGMEEVSVNLATEKLSV
                     SYDEKLLGLEDIRQAVEKAGYQLVDNLVTESYDISGMTCASCALTIEKALGKLEGVEE
                     VSVNLATEKATIRYSRHRQNPASLERAVEQAGYQLIRPEKVEGAADKGPSTEEKLRHR
                     FVWSAAFTFPLLYIAMGPMLPWGGLPLPALLHQPLVYAISQVILLIPILYIGRSFFQK
                     GFKTLLQGHPNMDSLIAVGTGAALVQGLLMIVFLQMGKEVAMHGHHPELYFESAAVIL
                     TLITLGKYFEARAKGQTSEAIKKLMDLAPKAAQVLRNGQEMQVPIEEVVVGDQVIVRP
                     GQQIPVDGQVLEGQTRVDESMLTGESLPVKKALGNNVFGGTLNQQGAITMQATKVGRD
                     TTLAQIIRLVEEAQGSKAPIAKLADQVSAIFVPVVMGLALLSGLAWYFLGQESWIFSL
                     SIIIAVLVIACPCALGLATPTAIMVGTGKGAENGLLFKSGQAIETLQGVNTIVFDKTG
                     TITEGKPQVTDIHLLSTKNREQVLQLAASSEQFSEHPLAQALLQAAQTEKIELLPATD
                     FQALSGRGLSVIIAEQTIYLGNERLMREQGIDVSKGRAVAEAFAQQAKTPVFLASQQE
                     VLAVIAIADKIKETSRQAVQALQTIGLEVVMLTGDNEKTAKAIAKEVGIEQVISQVLP
                     DDKANQVKFLQEQGKTVAMVGDGINDAPALAQAHVGLAIGSGTDIAIESADIVLMHSD
                     ILDVVKAVKLSQATMRTIKQNLFWAFAYNVIGIPIAMGLLHAFGGPLLNPMFAGAAMA
                     LSSVSVVLNALRLKTYKLYQKYQSKNWYFFT"
     gene            21140..21625
                     /gene="tpx"
                     /locus_tag="AC1PIV_000455"
     CDS             21140..21625
                     /gene="tpx"
                     /locus_tag="AC1PIV_000455"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008379 - thioredoxin peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0016684 - oxidoreductase activity, acting
                     on peroxide as acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HIP6611505.1"
                     /translation="MTTFIGKPVTLVGPQLRVGDVAPDFVLMANDLSLKSLKDFGKQT
                     KVISVVPSIDTGICDTQTRRFNQELADRDNTVVITVSADLPFAQKRWCGAAGLEDAIT
                     LSDYYDHAFGKSYGVLMREWNLLARAVFVLNADNEITYVEYLDNVNEHPDYDAALEAV
                     K"
     gene            21720..22055
                     /locus_tag="AC1PIV_000456"
     CDS             21720..22055
                     /locus_tag="AC1PIV_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HIP6611506.1"
                     /translation="MEKTQIIQDVLALIQDLNRAFQADKVGTADEQRFQHNLTETTRI
                     LSEAKSVTNTELIAIEKFYRSTSFLVGLGDLRLSETSRQAWRAFDRYYYETIREELKL
                     YGGSAIAQV"
     gene            22144..22845
                     /locus_tag="AC1PIV_000457"
     CDS             22144..22845
                     /locus_tag="AC1PIV_000457"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIP6611507.1"
                     /translation="MSYIQVKNSSKYYQMGDATIVANDGVSFEIEQGELVIILGSSGA
                     GKSTLLNILGGMDSNDEGEVWIDGVDIAKLSSHELTNYRRDDVGFVFQFYNLVANLTA
                     KENVELAAEIVKDALDAEEVLEQVGLGHRINNFPAQLSGGEQQRVAIARAVAKKPKIL
                     LCDEPTGALDYQTGKQVLQILQDMSRKQGATVIIVTHNSSLAPIADRVIRMRDARVHS
                     VELHAEPQDIASLEY"
     gene            22857..26222
                     /locus_tag="AC1PIV_000458"
     CDS             22857..26222
                     /locus_tag="AC1PIV_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HIP6611508.1"
                     /translation="MKKKIYWKDMRQSLLSSKGRFLSIFSLMMLGALALTGLKVTAPN
                     MEKTAQAYIASHRTMDLAVISGLGLSQADLDELETIEGATLEAGYFKDVVTNEGQTAI
                     RLFSAPKTLSTYKLVEGEVPSQKGQIALSASFKNRYKLDDTVQVTESDKDGKILTQTS
                     FTLVGFVASAEIWDNETMGMAVSGDGQLGGYGLVSQDTFKSEVYTIARIRYDDLVDLP
                     YYSQAYQDRLDQHQEDLEKLLANNDEQRLATIQSDGQTDISKGEEEIAQAQSQLEQAE
                     SELETGEEQLATGRSEFARGRAKVVQTEAELRAAQAQLLKNKFELEESKKELDGRKAQ
                     LEQTASFLDGYQMELEMSAQQLEEAKQELDSQNAQLSQTASQISTGRASWFQAQQELD
                     LEIANHLQEGQTLSDYPDLLARQEGLDVEKSRLDQMESAHEQANQAYLQGYDYYQTKQ
                     NEYNSNLAQYQTWNQEYQAGLARYQAGLSQYEQGIAAYNKGVEDYEWGLSQLESSNQL
                     LRQEELRLEEADKELSQAQSQFSDKKAVADQEISQAQTEIAQAKSDLSKLAKAPYQVY
                     TRSSLPGGDGYTTYSNATRSIAAVGNVFPVVLYLVAALVTFTTMARFVDEERTQSGIL
                     KALGYTNRQIMAKFILYGLAAGLVGTIVGIIAGNLLLSPLISDIITQTTVIGPAKLHF
                     YPLWTGLALLLSLVSSVLPAYLVARRELTEKPAQLLLPKPPVTGSSIWLEKWPAIWSR
                     LSFTHKVTARNIFRYKLRMLMTIFGVAGTVALLFGGLGIRSSISGVVQRQFGELIHYD
                     MLVVENSRATEEELDKLTHFLQSDQVRQSLPVAFEQLNQTVEENGQRKNLSISLYISD
                     RRDFGNQVSLESSTGQPIKLSDRGIVLTEKLAQIYGVSVGDKLSLTLEDKEVSVRVEA
                     VADMYAGHFIYMTDSYYEQVTGKQKTANAYLVQLKDSQLGHIQTLASQLLAMPAVRSL
                     VQNTSLIDMLTTIAGSLQTIMTILVILSILLGLVILYNLTIINMSERIRELSTIKVLG
                     FHNREVTMYIYRETIALSLIGMLVGLVGGIYLHKLLLAMIGSDSIRFNPSVGLEVYLI
                     PILAISGILSVLGWYVNHHLRKVDMLVALKSVD"
     gene            26392..27699
                     /locus_tag="AC1PIV_000459"
     CDS             26392..27699
                     /locus_tag="AC1PIV_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611509.1"
                     /translation="MKKISDLGLTGRKLVGEGLILVFIGIGFLIAGWQFPGLILRFVH
                     AGLFFLALYELSMTFFRKKKSSESVIALVGKAVLFGILASLDLAVQIPLYFAAIFVGI
                     YQLFTALINFITFYLYRKDGVQPRIRYLIDGIWLFLLGSASLFVSGTQLVVQTIVIGG
                     YLILYGLTNLRDGFLFEEAIEQQNLKRHVRLPLPLFLAALIPRMTLQKVNDYLADNEG
                     QTAQSIYNRHKEIAELPALEVFVHVGEEGFGAVGHVDLSYKGRVYGYGSYDVLSERLG
                     GAIGDGVLFKAERQAYIDFCNQEGMTMLGYQLSLRPEQEEAIETRLAEIDNLLLPWNP
                     SPEKVSKTVDGQPIEMYAYRMKEAIHAELFKFRKSKFKTYFVLSTNCVLLADSVIGQA
                     GTDILGMHGFIAPGTYQSYLDQEFEKPHSLVVAKNIYYRKEKS"
     gene            27775..30411
                     /gene="polA"
                     /locus_tag="AC1PIV_000460"
     CDS             27775..30411
                     /gene="polA"
                     /locus_tag="AC1PIV_000460"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HIP6611510.1"
                     /translation="MKKNKLLLIDGSSVAFRAFFALYNQIDRFKNANGLHTNAIYGFN
                     LMLDHMMKRIEPTHILVAFDAGKTTFRTEMYADYKAGRAKTPDEFREQFPFIRQMLDA
                     MGVKHYELDQYEADDIIGTLDKMAERTDIPFDVTIVSGDKDLIQLTDENTVVEISKKG
                     VAEFEEFTPAYLMEKMGISPTQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLTEFGSL
                     DGIYENIDSMKASKMKENLIADKEKAFLSRTLATIDTQAPIEIGLDDIVYQGPKVDEL
                     GQFYDDMGFKQLRAQLGTTSSQEEAVLDFQIVTEISPAMLKQDQFFYFEILGENYHRE
                     DLVGLAWGDKEKIYVGGPELLDSPVLRDFLESQTIKTYDFKRGKVLLDRKEIKLPPAT
                     FDSRLAKYLLSTVEDNSLTTIANLYGQTSLVPDEAVYGKGAKLDLPEREIFFPHLARK
                     VQVLIETEEPMLTKLEENQQLDLLFDMELPLANVLAKMEIAGIKVEAETLKAMQSENE
                     VLIDQLTKEIYELAGQEFNINSPKQLGTILFEDMGLPLEYTKKTKTGYSTAVDVLERL
                     APIAPVVSKILEYRQITKLQSTYVVGLQDAILEDGKIHTRYVQDLTQTGRLSSTDPNL
                     QNIPVRLEQGRLIRKAFVPSLENSVLLASDYSQIELRVLAHISQDQHLIEAFQQGADI
                     HTSTAMRVFGIEKAEYVTPNDRRNAKAVNFGVVYGISDFGLSNNLGITRKEAKAYIDT
                     YFERFPGIKNYMETIVREARDKGYVETIYKRRRELPDINSRNFNVRNFAERTAINSPI
                     QGSAADILKVAMINLDKALTEAGLATRMLLQVHDEIVLEVPVAELETVKAMVKETMES
                     AISLSVPLIADENEGSTWYEAK"
     gene            30398..31180
                     /locus_tag="AC1PIV_000461"
     CDS             30398..31180
                     /locus_tag="AC1PIV_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009910268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HIP6611511.1"
                     /translation="MKQSKKGKSMKKLILCIGLCSLLLAGCGKASQKTEKTPASSGEE
                     FSTTLPILQEKQDTTNEQFNVLANAEVVAVNSTPPADETQKGHKIYAANNGVAEKDEN
                     GNIKEYFRYYDVPSTWTINAENTKDETVAAVYDVKEGGSNYMVQIYNINAFNQSPLED
                     GRNMTPEELEARMVETNHSFSEKTVVTINGQEWQVGRQLLTDQKLARLTFYRMESTAA
                     YDDSVVVGSIYYSLDPGDDKKRTNLKKVIGQVKDVVYQIAKK"
     gene            31300..31737
                     /locus_tag="AC1PIV_000462"
     CDS             31300..31737
                     /locus_tag="AC1PIV_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HIP6611512.1"
                     /translation="MSYSFQNPSQDIIFDYLKNAKTIAVVGLSSREETAAYRVSKLMQ
                     EAGYKIIPVNPKAAGGTILGELVYSSLAEIDQPIDIVDVFRRSEFLPEVAQEFIQSNA
                     KVFWAQLGLESQEAEKQLRQAGRNDIVMNKCIKIEYLEMKEQY"
     gene            complement(32033..32875)
                     /locus_tag="AC1PIV_000463"
     CDS             complement(32033..32875)
                     /locus_tag="AC1PIV_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HIP6611513.1"
                     /translation="MFTISNIRERARQTLNETPGIYQVAVIPVTISVIVQLISFSRNS
                     LAGVSAEELASPSYFISTSLFPVFYGLLLGMLSLSVIWTIFNIIKGGKTTTSFKDSLS
                     IFNHKDFWKIFRTYILKSFLLFLWGLLFYLGIGLLIGAGTMITIIAASSQSLDPDALP
                     MEILAILGLMAMGGILLMVLGIALYIPQIYAYSQVEYILFEQLEREEYTGAFSIIKSS
                     RKLMKGYKFKRFTLDLSFIGWFLLVIITFGLAGLYVWPYHYAAQMHFHEEILDDQAKK
                     MSYV"
     gene            33195..34337
                     /gene="tgt"
                     /locus_tag="AC1PIV_000464"
     CDS             33195..34337
                     /gene="tgt"
                     /locus_tag="AC1PIV_000464"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HIP6611514.1"
                     /translation="MTDVPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTMSPEELKAMGSGIILSNTYHLWLRPGDELVARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNISEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFPGYSI
                     GGLAVGETHDEMNAVLDFTTPLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTNRGRLVVKNAQFAEDFTPLDPECDCYTCKNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLINLMKNVRQAIMDDNLLEFRQDFMEKYGYGKNGRNF"
     gene            complement(34376..35461)
                     /locus_tag="AC1PIV_000465"
     CDS             complement(34376..35461)
                     /locus_tag="AC1PIV_000465"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HIP6611515.1"
                     /translation="MSKLHHVKSYLEANKMDLAIFSDPVSIYYLTGYHSDPHERHMML
                     FVMPDHDSLLFLPALDVERAVATVDFPVAGYMDSENPWQIIKSKLPQKSFSAICAEFD
                     NLNLTRYHGLQSIFSQPFSDITPLINTMKLIKSRDEIEKMLVAGEFADKAMQVGFNNI
                     SLDVTETDIIAQIEFEMKKQGISKMSFETMVLTGDNAANPHGIPSTNKIENNALLLFD
                     LGVEALGYTSDMTRTVAVGKPDQFKKDIYNLTLEAHMAAVNMIKPGVTAGEIDYAARS
                     VIEKAGYGEYFNHRLGHGLGMSVHEFPSIMEGNDLVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGYVTKNGFEVFTKTPKELLYFEG"
BASE COUNT        10335 a         6891 c         8352 g         9924 t
ORIGIN      
        1 ctcgttgcct tgtactaaaa gcgaactaaa caactataat atctggttat cattgcaaat
       61 atttataagt gataatgtgt ataaaaaact gacagaaatt cagaaaaaac agaaaatgaa
      121 taggttgttt acagaaatat tccggaaatt gttggaaaaa caacaaatag agaggcgtaa
      181 tctgtttttt gtctgttttt catctcaagg agtcttgaca acttatctaa aaaggtgcag
      241 aatgaactcg caaacgtttg tttttttaat accatttttt atgtctattc atttcattag
      301 tgaaaacatg aaaggataaa acttatgaga aaaagttcgc acttgatttt aagctcaata
      361 gtcagtttgg cactcgtagg ggtcacacca ttgagtgttc ttgcagattc caaacaagat
      421 attaatcagt attttcaaag cttgacttac gagccacaag agattcttac aaatgaggga
      481 gaatacattg ataatccgcc agcaacaact ggtatgttag aaaacggacg ttttgtagta
      541 cttcgcagag aaaagaagaa tattacgaac aatagtgcag atattgctgt tattgatgct
      601 aaggctgcaa atatttatcc aggtgcttta ttgcgtgctg accaaaatct tctggataat
      661 aatccaacgc ttatcagtat tgcgcgggga gatctgacgc ttagtttgaa tttacctggt
      721 ttggccaatg gggatagcca cactgttgta aattctccaa caagaagtac tgttcgaaca
      781 ggggtgaata accttctgtc taaatggaat aatacgtatg ctggagagta tggcaatacc
      841 caagcagagc ttcaatatga tgaaacaatg gcatacagta tgtcacaatt gaaaacgaag
      901 ttcggaacct cttttgaaaa aattgctgta ccattagata tcaattttga tgccgtgaat
      961 tcgggtgaaa aacaggttca gattgttaac tttaaacaaa tttattatac agttagtgtt
     1021 gatgaaccag aatctccaag caagcttttt gcagaaggga caactgtaga agatttgaaa
     1081 cgaaatggga taacagatga ggtacctcct gtttatgttt ccagcgtttc ttatggacgc
     1141 tctatgttca tcaagttaga aactagcagt aggagtaccc aagttcaagc cgcatttaaa
     1201 gcagccatca aaggcgttga tattagtggc aatgctgagt atcaagacat tctgaaaaat
     1261 acttcattct ctgcttatat ttttggtggg gatgcaggta gcgcggctac tgttgtgagc
     1321 ggaaatattg aaacactgaa gaagattatt gaagaaggtg caagatacgg aaaactcaat
     1381 ccaggtgttc cgatttcgta ttcaaccaac tttgtcaaag acaatagacc tgctcagatt
     1441 ttgagcaatt cagagtacat agaaacaact tcaacagtcc ataatagcag tgcattgaca
     1501 ttggatcatt caggtgctta tgttgcgaaa tacaacatta cttgggaaga agtatcttac
     1561 aatgaagctg gagaagaagt ttgggaacca aaagcttggg ataagaatgg tgtaaatctg
     1621 acctcacact ggagtgaaac cattcaaatt ccaggaaatg ctcgcaatct tcatgtcaat
     1681 attcaagaat gtacaggatt agcatgggag tggtggagaa cagtttatga caaagattta
     1741 ccacttgttg gtcaacgtaa aataaccatc tggggaacaa cgttataccc acagtatgcg
     1801 gatgaggtga tagagtaatc tggcaatgta ttatactctc ttagccacag aggctaggag
     1861 ctaaacacta ttcgtcagaa acttatcaca agaaaatggt attaaaataa ggattctatt
     1921 caaattttgg gtagaatctt ttatattttc ctaaaaacta cttttaggta tgagaactcg
     1981 ttctgaaact attttcagga ttttttgtat ttctacaaaa atcgaaatta cattctaaat
     2041 aaaaagaggt tattgaaaaa ataataatat actatataat aaacaatgta agcgctatct
     2101 ctagtatgga gcagaaagga atgacataat gggcactatt agtaagacag atttaaagca
     2161 acaaattaag gatggaatta tcgtttcctg tcaggctttg ccaggcgaac ctctgtatag
     2221 ggaagaaggc ggtattatgc ctttactagt caaggctgcc caagaagcag gggctgtcgg
     2281 tattcgggcc aatagtgtac gagatattaa ggagataaaa gaagtaacta ctttaccaat
     2341 tatcggaatt atcaagcgag actatcctcc acaagagccc tttattacgg ctacgatgcg
     2401 agaagtagac gagttagcag ctctagatat tgaagtcatt gctcttgatt gtaccaagcg
     2461 tgagcgttat gacggactcg atattgttga tttcattaag caaatcaagg aaaaataccc
     2521 cgaacaactt tttatggcag atatttcaac ctttgaggaa ggattaactg cttatgaagc
     2581 aggcatcgat ttcattggga caacactttc ggggtataca tcctatagta ggcaggagga
     2641 gggaccggat attgaattgg ttgaccgctt gtgccgagca ggtatcgatg tgatagcgga
     2701 aggaaaaata cactatcctg accaagtaaa aattattcat gatttaggtg tggcaggaat
     2761 tgttgtaggc ggtgcgatca cacgtccaaa ggaaatcgca gagcggttta ttagtgcttt
     2821 acataaataa taaataggtt atagaaagga atggagtatg aattttaaga agttttctca
     2881 gctaggtcag gcctttatgc tgccaatctc aattttgcct gttgctggtc tcttactggg
     2941 aattggaggc gctttatcaa atagtaatgc tgtagcacaa tttcctgtat tggatcaagc
     3001 gtggttgcaa gctgtattca ctatcatgag tacggcaggt agtgcggtat ttgcgaattt
     3061 agcattgatt tttgcaattg gtgttgctgt aggtttggca gatgctgata aggggactgc
     3121 tggcctatct gctggggttg catacttggt ttatacggct actattagtg gatttttaac
     3181 tctttttgct gataagggag caagcattga tactggagtt ttgggcgctt tagcgattgg
     3241 tatcactgtt gcaactttac acaataaata tcgaaaaatt gaattaccag cctttcttgg
     3301 tttcttcggg ggctctcgtt ttattccaat tatttcatca tttgcagcaa ttgcgattgg
     3361 ctccattttt tatataattt ggccaccgat tcagaattta ttagttgatt ttggtaaggc
     3421 aatagcagag atgggaagtt ttggaacctt cttatatggt tttggattgc gtttgacagg
     3481 tgcatttggc ttgcaccata ccatctatcc aatgttttgg tatacttcat taggtggaag
     3541 tgaagtggta gcaggtgaga cgatccaagg tgcgcaaaat attttctttg ctcaattagc
     3601 agatgcgaat cacacaggct tatttactta tggaactcga ttttttgctg gtcgatttgc
     3661 aacgatgatt tttggtctac cagcatcttg tttggctatg tatcacgcaa ttcctaagga
     3721 aaatcgtaag aaggtaggca gtttttattc aagtagtgca ttaacttccc tattgacagg
     3781 aattactgaa ccaatcgaat tttctttctt gtttgttgct ccatggctat atgttgttca
     3841 cgcattttta gatggactat cattcttagt cgcagatctc ctgcaaattc gtattgggaa
     3901 ctcattttct ggtgggctta ttgattactt gatttttggt gttttccaag gaaatgacaa
     3961 aaccaattgg atttacgtga ttcctgttgg cttgctttgg gcagcagttt attatctagt
     4021 tttcaaattt ttagtaacca aatttcacgt gctagttcct ggtatggaaa gcagtgacca
     4081 agcatcacat tcggaaaaag ttttatcaaa cggttctagt cttcgtgata atgcaattgc
     4141 tatcatcgat gctcttggtg gagcagataa tattgagaat gtgactgcct gtgcgactcg
     4201 attaagagta tcgctcagaa atagtggtct tgtggataag ggagttattc agtctatagg
     4261 tgcaacggct gttttggatg taaaaggagg aatacaggct attttcggag gtaaggctat
     4321 tctgtatagc caagaaatca atcaaattct tggtcttgaa gaatagagtt atatttaagc
     4381 gaattaaaag cattcaaact gtacctatcg ggtatttttg aatgcttttt gttttattaa
     4441 gattgttgtg aaatagaaag acggatgaat tattctctaa tggtttgctt gaaaatattc
     4501 tcttttttct ccttgtcaat agctaaaaaa taggcgtaga taatatctag catgatgagc
     4561 agggggattt ggggtgagat acgattgccg taattgaggt ggcggacaga ggcgacagga
     4621 atgatttggt caaaagtcgg atggggaaaa ctcctagttg ttaacagggc ggtaggaatc
     4681 cccttttgag cagccagctg gagatgctcc atgacctctt ctgtctgacc agacagagaa
     4741 agaccgataa ccaggcaact atcatccaga atattggtag tccagatgag attgttttca
     4801 tcagtaattg catcacagac tacacccagt cgcataaagc gggatttgat ttccattgca
     4861 accaaaccag aactgccgat tccgtaaaaa tagacacgct tgctactgtc aatcagtttg
     4921 gcaatctctt ctaatttttc ctcatctacc agtttattgg tagcagttag gatttcctca
     4981 tagtctacca agactttttt tgttaggctc cgctgtaatt tttcaaaatg tttatccaag
     5041 tattgttggt tattctgaaa ggcaaagaca aattctcgat aaccggaaaa tccacatttt
     5101 ttggcaaaac gggtaagagc agatggagaa atgtggagtt gctgtatagt gttttcttgg
     5161 ctaagatcgg cgctagatgg gtctaactga gtaaaataac tggcaatctg cttttcaagt
     5221 ctagtcatct gatccagatg agactcaatg atggcagtaa tgtgtttcgg tgtttgtaac
     5281 attttccatt cctctgatag cttctgagga cattatacca ctaaaaaacc ctcattgata
     5341 ggttttatga tataatggaa acgtaaaagg aatgtaagat tatgtatatt gaaatgattg
     5401 atgaaacagg gcaggtttct gctcaaatgc aggagcagat tacggaattg ctccagtttg
     5461 ctgccgaaaa aattggcaag cagaataagg aaatggctgt gacctttgtg gacaataagc
     5521 gtgtccatga ggttaacttg gagtaccgag gaattgaccg tccgacagat gttgtcagtt
     5581 tagaatataa gccagagtcg gagattgttt ttgatgagga agacttactg gacaatcctg
     5641 aattggctga aatgatggaa gatttcgatg cctatattgg tgaattgtat atttctatcg
     5701 ataaggcacg tgagcaagct gaagattatg gtcatagcta cgagcgcgaa atgggctttt
     5761 tagctgtaca cggttttctg catatcaatg gctatgatca ttatacgcca gaagaagaag
     5821 cagaaatgtt tggtttacaa gaagaaattt tgacggccta tggacttaca agagaataat
     5881 tcaaaaaatc gctggaaaaa ccgagaattg attgctagtc tagaatttgc agtaacaggt
     5941 ttgttgacag ctttcaagga agaacgcaat atgaagaagc acctggcttc agctgtcctt
     6001 gttgtgcttg cgggacttat tttccaagta tctgtgacag aatggctctt cctcttgctc
     6061 agtattagtc tagttatcgc ttttgaaatt gtgaattcgg ctattgagaa tgtggtggat
     6121 ttggcgtcag actatcattt ttctatgttg gcaaagaatg caaaagatat ggcagcaggg
     6181 gcagtcttgt ttgtgtcagg atttgccttg ttgacaggat tgattatctt tgtgccgaaa
     6241 atttgggact ttatttttta gaatataagg agaatacatg acatttaagt caggttttgt
     6301 ggcgatttta ggtcgtccaa atgttgggaa atcaacattt ctcaactatg taatggggca
     6361 gaaaattgcc atcatgagcg acaaggctca aaccacccgt aacaagatta tgggcattta
     6421 tacgacagaa gaagagcaga ttgtcttcat tgacacacca ggaatccaca agcctaagac
     6481 agccttgggt gactttatgg tggaatctgc ctatagcacc cttcgtgaag tggatacggt
     6541 cctctttatg gtgccagccg atgaaaagcg aggcaagggt gacgacatga ttatggaacg
     6601 ccttaaacag gccaaggttc cagtcatttt agtggttaac aaaattgaca aggtccaccc
     6661 agaccagctt ttggaacaga ttgatgattt ccgtcaacag atggacttca aggaaattgt
     6721 gccaatttct gctacccaag ggaacaatgt caaccgactc atggaaattc tcaaggaaaa
     6781 cctggacgaa ggcttccagt atttcccggc ggaccaaatc actgaccacc cagaacgttt
     6841 cttggtatct gagatgattc gggagaaggt tctacacctg actcgtgagg aaattccgca
     6901 ctctgtggcc gttgtcatcg agtccatgaa acgtgatgaa tttaccgaca aggtccacat
     6961 tcgcgctacg attatggtag agcgtgatag ccagaaaggc atcatcatcg gtaagcaagg
     7021 agccatgctc aagaaaatcg gctccatggc tcgtcgtgat attgaactca tgctaggtga
     7081 caaggtcttc ctcgaaacct gggtcaaggt caagaaaaac tggcgagaca aaaaactcga
     7141 cctcgccgac tttggttata atgagaaaga gtattaaaaa cgtccggggg acgtttttaa
     7201 cccgagcttg gaaactagag agcgaggaag ttcgagggag tgaaacagtc tgtgaataga
     7261 ctgtttcagc tggtcacata gaaatgttaa agtggccatt tgaaaaaacc gagcttgaaa
     7321 actagagggc gaggtagttc gggggagtga aacaatctag gaatagactg tttcagcagg
     7381 tcacatagga atgtgaaagt gaccatttga aaacccgatc ttagaaattg gaaggcgaga
     7441 tagcctgggg ataggctgtc taagtcaatc acttagaaat agttagcaga aaagccgaaa
     7501 ggcttttact gcgttatgga gaaatctttt tagtaaacaa gaaaggaaag ccgattaggc
     7561 gttgtcttga actcgcctac gactctttga aaatcacaac cgtgacctag gtgccgaagc
     7621 accgtcggtc aggtttctat ttgctttgta attttgttag aaaggatgag tgtttgcgta
     7681 cttgaacccg agctaaaagc tcggaaaata gatagagctc cttgtgtgca agtcacacag
     7741 cgtcgctctc ctaattttca gtcgcttttt acgctcttgg tatcgtaaat tgcccgaatt
     7801 gcctgaggtt gagacggttc gtcgtggttt gaatcgtttg gtcaagggaa aagttatttc
     7861 caaggtggag gtgacctatg ctcccatgat taagacaggt gtggatgcct tctgccaaga
     7921 cttgattggt caggagattt tagatgtgga ccgtcgtggc aagtatctct tgatttacct
     7981 gacagaccat gtcctcattt ctcatttgcg gatggaaggt aagtacaatt tctttgctga
     8041 ccaggtgcct gccaacaaac atttccatgc cttttttact tttatagatg gctcgacctt
     8101 ggtctatcaa gatgtccgca agtttgggac catggaactg ctgggtaagg cagatgtgga
     8161 tgcctatttt atcagtcgaa aaattggtcc tgagccgacg gaggaagatt ttgacttaga
     8221 agaatttgcc aaaaagttag ctaagtcgaa aaagcccatt aagtcgcatc ttttggacca
     8281 gtctttggtg gctggtttgg gcaatattta tgtcgatgag gtcttgttca aggccaaagt
     8341 tcatcctgca caaacgagta atcagctgtc gacagatcag gtggcagacc tccgtcaagc
     8401 caccattgaa gtcctgcaac tgggtattga aaaaggtggt tcaaccattc ggacttacaa
     8461 aaatgccttg ggcatggatg ggactatgca ggattattta caagtttacg gaaagacagg
     8521 gcaggcctgt ccccgttgcc agacagagat tgtcaaaatc cagctgggcg gacgggggac
     8581 acatttctgt cccaagtgtc aggtgaaaca tggctaaaat tatcggttta acaggcggaa
     8641 tcgcctctgg aaaatcaaca gttacagctt ttctgagaga acaaggttat ccagtcattg
     8701 atgcggatgc ggttgttcac gaattacagg ccaaaggtgg caagctctat cagattttgc
     8761 tgaaagagtt tggtccagac atcttgtcgg cagatggaca tttagacagg gtcaagctgg
     8821 gtcaggctgt ttttgcggat agcaagttgc gggctcgcct gtctgacctg caggaccaaa
     8881 ttatcaggca ggagctgtta gacagaaggg atgctctaaa acagacggag caagttcttt
     8941 tcatggatat tcctttgctt tacgaggcag attatagcgg ggaagtaaat gaaatctggc
     9001 tagtttatgt cgatagagca cagcagttgg aacggcttat gaaacgtaat ggcttagctg
     9061 ttcaagatgc agaaaatcgt ctggctgctc agctttcttt agaggaaaaa cggtcgcaag
     9121 cccaggtggt gattgacaat agcggagcgg ttgaggcgac cttagcacag gttgctcagc
     9181 ttttggagga attaaaggat ggacgacggt agtagttatt ggaagcagaa tttgaaggtg
     9241 gcttggttgg gaaatttcct aacagggacg agttttacct tggttatgcc ttttatctca
     9301 gtttttgtgg aagagttggg ggtaggtcct ggacaggtag aatattatgc ggggcttgcg
     9361 gtatctgtta atgcccttgc ggcagccttg atggcaccta tttgggggag tttggcggac
     9421 cgttacggtc gcaagcccat gatggtgcga gcggcctttg ccatgatttt tactatgggt
     9481 ggtatggcct ttgtaccaaa tgttttttgg ttgcttacct tacgtgtcct aaacggggta
     9541 tttacagggt acattcccaa tgcgactgcc ttgattgcca gtcaggttcc aaaggataag
     9601 acggggtatg ctctggggac cttatcaaca ggtgcggtag caggtaattt gattggtccg
     9661 accctaggtg gtatcttagc agagatgttt ggcgtacata tggtattttt gctggtggga
     9721 cttctttatg ctatcgttgt gttactgacc gttttctata ttcgagagga ttttgttcca
     9781 gtcaaaaaag gcgaagagat gtcggttaaa gaggtatttg agcaggtgaa agatcggcag
     9841 atgctggttg ggctttttgt gacttctatg attattattg cagctgctca ggctgttgtt
     9901 cctatattga ccctctatgt gcggcatttg ggacagacag ataatctgtt atttgttgct
     9961 ggttttatca tttccttgcc tggtatggca tcgctagtga catccggtta tttagggaaa
    10021 attggtgatc gtattggcaa ccatcgactt ctattaattg ctttgactta cagtctgttg
    10081 attaatgttt tctgtgtttt tgcagaaaat cctttccagc ttggtttgtt gcgattcatg
    10141 tatggttttg ggacaggagc actgttgcct tcggtcaatt ctcttttgac caagttgaca
    10201 ccaaaagaag gaatttcaag gatattttcc tacaaccaac tctttaataa tctaggttct
    10261 gttgttggtc ccatgatggg gtctgcggta gctgctcaca tgggttatga ctgggttttc
    10321 tatctgtcga gcggacttgt cctctttaac cttatctggt ctttgaccaa ttttagaaac
    10381 tatttgaaag taagggatgt ttagtgagag ttaaaatcaa tttacaatgt tcagaatgtg
    10441 gtagtaagaa ctacttgact agcaaaaacg ccaagactca tccagataag attgaagtcc
    10501 ttaaatactg cccaaaagag agaaaagtaa ccctccacct tgaaactaag taggttttat
    10561 ggtataatgt cataagttat tgtagaaagt gaaaaaaata tgtatcaagc attattagca
    10621 attctgttga ttttatctgt tattttgatt gtagtgattt ttattcagcc agcaaaaaac
    10681 cagtctagca acgtctttga ctcttctagt ggagccttat ttgaacgtac aaaggcccgt
    10741 ggttttgaag cggtgatgca acgtattacg gctattctga ttttcctatg gatgttggat
    10801 gcgctggcac ttgttatcat ttcaagtaag tagataaatc agactgggac ttgttcttgg
    10861 tctatttttt tgggagtggg ccagaactcg acaagtataa agagttcgtc tgcccacctc
    10921 cgcataagtt gaataggtat ggttcggagc gttattcgcg aactattgag atttgctttg
    10981 caaatcctat ctcccacctc caacaatcat ttgattgttg gagcaatcaa ccactgcgtc
    11041 tggatataac gcaaaataca gtcttttagt ttgcttttag tactaggcaa cgagctgcag
    11101 actgtactga agtacgacaa agcgagttca aataatgatg aaattatttg aagttggaaa
    11161 tagggaaacg gagtttcctc gtacgtcgca gtaataaaag ataaactaaa ggactgaaag
    11221 agaaatagtg ctagattctt aactagcact ctggtaaata caagatgaaa aacgaaatta
    11281 taaactatat taaagaagtt ggtcctgtga ccatggacca gctggcagat cagtttggag
    11341 ccagttctgc taagagcttt acagacttgg tcaagctggt ttctagcatg gaaggcagtc
    11401 gtcaacttgt ctttgataat gctgggcgga ttactcttcc tgctccaaaa atctctaaga
    11461 acaaggtaac cttacagggg attttccgtg ctcacaagtc aggttttggc tttgtgacca
    11521 ttgatgaaga ggaagatgat ctctttgtca gccgtgacga tgtcaacttc gctatcgagg
    11581 gcgaccgagt ggaagtggct atcaagaaag tggcggacag gttcaagggg acggctgcgg
    11641 aagcggaagt cattgatatt ttggaacata gcctgaaaac agcggtgggc ttgattgtct
    11701 ttgacgaaga caagccagag tatgcaggct acatcaagtc taaaaaccag aaaatcgctc
    11761 agaagattta cattaagaag tcacctctgg tattgaccgg aacggaaatc ctcaaagttg
    11821 acattgaagc ctatccaaac aagaaacggg accactttgt tgcgaccatt cgggacgtgg
    11881 tggggcataa ggatgatgta gggatcgatg tcttggaagt tttggaatcc atggatatcg
    11941 tgtcggaatt ccctgacgaa gttttggcgg aggccaatcg ggtaccagaa agtccgtctg
    12001 agaaggactt tgaaggacgc ttggacctgc gagatgagat catctttact atcgacggtg
    12061 cagatgccaa ggacttggat gatgcggtcc atatcaagca gctcaagaat ggcaatctgg
    12121 aactgggtgt ccatatcgct gatgtcagct actatgtgac tgagggctca gccttggacc
    12181 aggaagctgt caagcgggga acctctgtct atgtgaccga ccgtgtggtg ccaatgctgc
    12241 cagaacgttt gtcaaacggc atttgttccc tcaatccaaa tgtggatcgc ctgacccagt
    12301 cggctattat ggaaattgac tgcaagggca aggtggtcaa gcactggatt ggccaaacgg
    12361 ttatcaaaac caccttccgt atgacctatt ccgatgtcaa tgacatgatt gcaggtaaca
    12421 aggaaaagct ggacaaatac aagacaatcg tgccaagtgt tgagctcatg gtcaaactcc
    12481 atgaaaccct ggaaaccatg cgctacaagc gtggggctct caactttgat acagctgaag
    12541 ctaaaatcat cgtcaacaag gatggtctgc cagtcgatat tcaactgcgc cagcgaggca
    12601 ttgccgagcg gatgattgag tccttcatgc tagctgccaa cgagtgcgtt gccgagcatt
    12661 ttgctaagtt ggacttgcct tttatctatc ggatccacga ggagcctaaa tcagacaagt
    12721 tgcagaagtt catcgactat gcgactagct ttggtctgac ggtatatggt acagccagct
    12781 ctatcagcca ggacgccctt caggatctca tggagcgggt caaggatgaa ccctatgcgg
    12841 acgtcctcaa catgatgttg ctacgttcca tgcaacaggc gcgttactca gagcacaacc
    12901 acggccatta cggactgggt gcggagttct acacccactt caccagtcct atccgccgtt
    12961 atcccgacct gctggttcac cgtatggtgc gggaatatgg tcacaatcct tcggaaaaag
    13021 cagagcattt tgagcaggtc attcctgagc ttgccaagtc ttcatccagt ctagaacgcc
    13081 gtgccatcga tgcagagcgg gaagttgaag ctatgaagaa ggcagaattc atgcaagaat
    13141 ttgttgggca agagtttgat ggtgtcgtat ctagcgtagt caagtttggt ctctttgttg
    13201 agttgccaaa caccgttgaa ggactgatcc atgttaccaa cctcaacgag tactaccagt
    13261 tccacgagcg aactctgacc ttgcagggtg agaaatcagg tcgtgtcttc cgtgtcggtc
    13321 agccaatccg tatcaagcta acgcgggcgg acaagatgac aggggaaatc gattttgccc
    13381 acatgccgtc cgaactggat attgtcgaaa aagctttgaa agccaagcgg agaactgcta
    13441 gtcactccaa ccgtgaccgt gatgatcggt cagggcgagg acggggcaag cactacaaac
    13501 aagaagctgc tggtcgcgac agcggacgtc acaagtctgg aaaagaccac aagtcaaaaa
    13561 gtggcaaaaa agacaagaaa aagaaaccat tttacaaaga agtggctaaa aagaacaaga
    13621 agaaaaggag ataggcatgg ccaagggtga gggcaatgtg attgcgcaaa ataaaaaagc
    13681 ccgccacgac tataccattg tcgatacagt ggaggcgggg atggtcctga cggggacgga
    13741 gattaagtct attcgtgcgg ggcggatcaa ccttaaggac ggctttgccc agatcaagca
    13801 gggcgaggct tggttggtca atgtccatat cgctccctac gatgagggca atatctggaa
    13861 tcaggagcca acacggaccc gcaagctcct cttgcggaag aagcaaatcg agtctttgga
    13921 caatgaggtc aagggaacag ggatgactct ggtgcccctc aaggtctata tcaaggatgg
    13981 ctttgccaag gttttgattg ggcttgccaa agggaagcac gactacgaca agcgggagtc
    14041 aattaaacgc cgtgagcaag accgtgatat caaacgaacc atgaaggcta tcaatagtcg
    14101 atagaggctg ggagaaatcc cggtcttttt tgttatagga aaacaaatac cccagacagt
    14161 ttcgagacta tctggggctt attatttatc ttaatccacc gtaatcatag ctttaatcgt
    14221 tttccggttg gccatgtctt tgtaggcttg gtcgatattg tccaggctgt aagtttgggt
    14281 gaaaactcga cctgggttga tgtcgccttt gagaacagca tcaagcaaaa tttccttatc
    14341 ataggttgtg acagaagcag agccaccacc gataatgata ttttgagcaa aagttgatcc
    14401 gagggcgtgg ttgttgtaat gaggcacacc aacaaaaccg atgcgaccgc cattatgaag
    14461 gacgccgagg gcttggtcaa tagaagcttc tgttccgaca cattcgaggg cagcatcagc
    14521 gccacctcca agaatttcac ggactttggc aattccttcc tcgccccgtt cagcaacaac
    14581 agcagtagcc cctgattcca gagccatttg ctgacggtca gcatgacggc tcatcatgat
    14641 aatctgcgaa gctccccgca tttttgcagc aatgacggca cattgcccca ctgcaccatc
    14701 accgatgaca accaccttat caccaggttt gacatctgca acacgcgtag catggtagcc
    14761 tgttggcata acatctgcca gagtcaagag agatttgatc atgccttctg agtagtcgct
    14821 tggctgacca ggaattttga ccaaggccca gttaccgtag tggaaacgaa tatattgaga
    14881 ctggtagttg ttgccccagt tggtgtagcc tggatggttg tcacaagtac cgtcaaagcc
    14941 agcacgacag gcatcacagt gtccgcaacc atgtgtaaat ggaacgataa cgaagtcacc
    15001 aggaacaagt gttgtaatgt cttcgcctac ctcttcaacg ataccgatgg cttcatgacc
    15061 agagtttgtg tcaccgtggt catggtgaat gtcttctccg tagccccaaa ggtccgaccc
    15121 acagacacag gcccgaacga ccttgataat gacgtcatct ttggcttgaa ggcttggttt
    15181 ttcgatttct gcaacggtca tcttaccggc tttttcataa atagctgctt tcatattttc
    15241 tacacaccta catttattaa taaatgtcct ttctgattga tatggaatat tatacacctt
    15301 ggagttcact ctaagtcaag tgaaaatata gatttgaaat caagatttct ttgtgataga
    15361 ctagaaacac gttttaagtt ttgtagacga aaaggagaga taatgactgt tttagttcct
    15421 tacaaacgca tgcctatttg gaatcaggat acggttcccc agcatttttt gaccaagcac
    15481 aataccaagg taggtacttg ggccaaaatc aaggtcttga gaggtcaact taaatttgag
    15541 ccgatttcag atgataatga aattttggga gaatttgtct atggtccgac agatgatgtt
    15601 ccctttgtcg agccacaggc ttggcatcgg gtgactttgc tgacagagga tacggagttt
    15661 ttcttggaat ttttctgtca accagaagac tattttgcca aaaagtatga ctatactcgg
    15721 acacattcgg aagtcttgga ggccttgaag agaattgagc cttgtaaggt cttggacttg
    15781 ggctgtggtc atggcaggaa cagtctctac ttggcccagc aggggtttga ggtaactgct
    15841 gtagataaag atgtaccaag tattcggaca ctcttgcagg tcaaggaagt agaagatttg
    15901 gacttgcagg ctgggactta cgatattaac tcagctagtc tggagcagga ttacgactgg
    15961 attatctcaa ccgttgtctt tatgttcttg gagcgggagc gggtgccagc tattatccgc
    16021 aatatgcagg agcagacacg acctggtggc tataacttga ttgtggcggc catggataca
    16081 gaagatgcgc cctgtcctat gaatttctcc tttacttttg gagtaggtga gttgaaggaa
    16141 tactaccgtg actgggaact ggtcaagtac aatgaagatt tcggtcaact tcacaagcgg
    16201 gatgaaaatg gccatttcct caagatgcgg tttgcgacca tgctggctag gaaaaaagga
    16261 taaatatttt tttgaaagca cttgcaaggc aggtgctttt gcgttacaat gtaggtgcaa
    16321 atgggtaaat catattatac tccacgaaaa tcaccttctg gttggataag agacttgtgt
    16381 aaaatagtct ctgagtttat atctctggag ggcgcctact tctgattttc acagagtatc
    16441 aggaaaggag aagtctatga aaaagacttt tgttcgtata gccacatttc taatgttggt
    16501 ttgcctattc cctgttcaac ttgttcaagc ctgttcaggc tttattattg ggaaagggtt
    16561 gacaacggat ggttctatcc tttatggtag aacggaagat tatccatatc caccaaataa
    16621 tggagcgcac aataaaaatt atattgtggt tccagcaaca gcctatgcca agggggatat
    16681 gttggtggat gaatcattcg gtttcacagc accacacttg gcaaatgagt tcaagtacac
    16741 ctctacgcct gatgcggcac gtggggatgg gtcaaacggt aattttggtg cgcatggatt
    16801 taatgaaaaa ggtgtgtcca tgactgctac tgttacagct attccaaata aaaaagtttt
    16861 agctgttgac ccattggtaa ctgcgggggg actaggtgag gccattttga ttgactatgt
    16921 tcttcctaga gtcaccagtg cgcgtgaagg tatcgaatta attgcgaaga caattgatga
    16981 aaaaggttcg gcagaaggga atatcattgt tattgctgat aagaatgaag tttggtacat
    17041 ggaaattttg tcaggtcacc aatacgtagc catcaaattc ccagaagaca agtatgcaat
    17101 ttttgcaaat acttactatc taggtcatgt tgattttacc gatacagaaa atgtgattgc
    17161 ttctgcaaag gttgaagaag tagccaaaca ggctgaaaat tatatgatgg ttgatgggaa
    17221 gttccatatt gccaaatcat atggacctga gaattatgct gatggtgatc gttctcggac
    17281 atacgctggt ataaaattgt tagatccagc atcgtctgta acctatgaag atgctgtgta
    17341 tgatttgcta cgtcagccaa cagacccaag tcgtcgcttt agtttacaag atacctttgc
    17401 cttacaacgt aaccgttttg aacatcttcc agaatttcgt ccagacgatg aagcaggtaa
    17461 ggtaaaacaa ggggataatg gtgcgaatga ccaagcggca gatgcgactt ataaatacgc
    17521 tcttggtaat gaaaacgtca tcgatgccca tgtttatcag attaatagta gcttaccatc
    17581 agccttcggt ggcacagtat ggttgggctt ggctcagaca aggaatacac cgtatgttcc
    17641 attttatggt attgtgactg atacttatga agcctttaaa aatcgctcag cttcttatga
    17701 taccaattca tggtactgga cggtacaaaa tattgataag atggccatct cacacccaga
    17761 gttatttggt acatcaattc aagaaaaatg gattgcactt gaaaaagaat ggattgcttc
    17821 acaggcagct cttgatgctc aatatgccgg actttcagaa gatgcagccg tagctctggc
    17881 tccaactgta acagaggcaa ccttggctcg ttcagcagag atttttgccc aactaaaagc
    17941 tgttgaagct gaaatgatgg caaaaattga agcagcaaca actccgtcat caagtagtac
    18001 tgaaccatcg accagcactg agccatcatc aagtggtacc gaaacttcaa ccagtacaag
    18061 tcagtctaca agtgattcta acacaggagg agctacggat acttcctcat caagccgaac
    18121 agtagtgcct tctgataaga aagtaacacc taccaataaa aaaggtaaat caagtcttcc
    18181 tagtacaggt gagcaagtca gcctcttgtt ggtggcgcta ggtgttgcag gaattttaac
    18241 agcaattttt cttcatcgaa aaaaatccag taaagaataa atagagctag taagaaatag
    18301 gttggggtct ctccaatcta ttttttatac tcaatgaaaa tcaaaaacag acttgctcca
    18361 aaggtttggg gaacctttgg aggttggaga tagagcgaac ctagttcgta tcgatatgat
    18421 gtagatagaa cactgttcct tttatatttc aagggaacag gctgaaaacc tccacaggag
    18481 cttttcagtc atcaaatcaa gtcaacaacg tctgattttg attttcgaag agtattaatc
    18541 aaaaatgttt acaaacgtag tcgtatattg tataatttgt ttacagatgt agtcggaaaa
    18601 ggagtaacct atgaaacaag caagctatcc cattcaaggt atgacctgcg cttcctgtgc
    18661 tctgacggtt gagaaagcgg ttggtaaact agcaggaatg gaagaagtca gtgtcaacct
    18721 agcgactgaa aaattgagtg tcagctatga tgaaaagctt ttgggactag aggatattcg
    18781 tcaggcagtt gaaaaggcgg ggtaccagct agtcgataac ttggtgaccg agtcttatga
    18841 catttcaggc atgacctgtg cttcctgtgc tctgacgatt gaaaaagctc tgggcaaact
    18901 agagggtgta gaagaagtca gtgtcaatct agcaacagaa aaggcgacta tccgttatag
    18961 ccgtcatagg caaaatccag ctagtcttga aagagcagtt gagcaggcag gttatcagtt
    19021 gattagacca gaaaaagtag aaggggctgc ggacaaggga ccgagcacgg aagaaaagct
    19081 gaggcatcga tttgtctggt cagcagcatt tacttttcca ctgctctata ttgctatggg
    19141 tcctatgttg ccttggggag ggcttccgtt accagctttg ctccaccaac cgctagtcta
    19201 tgcgatcagc caagttatct tgctcatccc tatcctctat atcggacgca gttttttcca
    19261 aaaaggcttt aaaactctct tgcaaggcca tcccaatatg gattccttga ttgctgttgg
    19321 gacaggggca gccttggttc aaggtctttt gatgattgtg tttcttcaga tggggaaaga
    19381 agtggccatg cacggtcacc atccagaact gtattttgaa tcagccgccg ttatcttgac
    19441 attgattacc ctaggaaaat attttgaagc tagagccaaa ggtcagactt ctgaggcgat
    19501 taagaaattg atggatctgg cccccaaggc ggctcaggtc ttgcgaaatg gtcaggaaat
    19561 gcaagtgccg attgaagaag tggtggtcgg tgaccaggtt attgttcgtc ctgggcaaca
    19621 gattcctgtt gatggtcagg ttctcgaagg ccagacacgt gtggatgagt ctatgctgac
    19681 gggtgagagc ctaccagtga agaaagctct aggcaataat gtttttggcg gcacccttaa
    19741 ccagcaaggc gccattacca tgcaggctac caaggttggt cgtgatacga ctctggccca
    19801 gattattcgc ttggtagaag aggctcaagg ttctaaggcc cccatcgcca aattggctga
    19861 ccaagtatct gcaatatttg taccagtcgt catgggcttg gctctcttgt cgggtctggc
    19921 ctggtacttc ttgggtcaag aatcatggat tttttcacta agtattatca tcgccgtctt
    19981 ggtcatcgcc tgcccttgtg ctctgggctt agcaacgccg actgccatca tggttggtac
    20041 tggaaaaggt gcagaaaatg gccttctgtt caagtctggt caagctattg aaaccctaca
    20101 aggtgtgaat accattgtct ttgacaagac tgggaccatt actgagggca aaccccaggt
    20161 gacagacatc cacctcttgt ctactaaaaa tcgtgagcaa gttctccagc tagcagcaag
    20221 tagcgaacaa ttttccgaac atcccttggc tcaggctctc ctgcaagcag ctcagacaga
    20281 aaagattgaa ctcttgcccg ccacagattt tcaggcactt tctggtcgtg gtctttcggt
    20341 gataatagca gagcagacca tctatctggg aaatgaacgg ttgatgcggg aacagggaat
    20401 tgatgtttcc aaaggacgtg cagttgcgga ggcatttgcc cagcaagcca agacgcctgt
    20461 tttcctagcc agccagcaag aagtactagc agtcattgcc attgctgata aaataaaaga
    20521 gaccagccgt caggctgtcc aggctctgca aaccatagga ctagaggttg tcatgctgac
    20581 aggagataat gaaaaaactg ccaaagccat tgccaaggaa gtcggcattg aacaggtgat
    20641 cagtcaggtc ctaccagatg acaaggctaa ccaagtcaag ttcttacaag aacagggcaa
    20701 gacagtcgct atggtggggg atggcatcaa cgatgcccca gctctagctc aagcacatgt
    20761 gggtctagcc attggttcag ggactgatat tgccattgag tctgccgaca ttgtcctcat
    20821 gcatagtgac attttggatg tggtcaaggc tgtcaaactc agccaggcaa ccatgcggac
    20881 catcaaacaa aatctcttct gggcctttgc ttataatgtg ataggtattc caatcgccat
    20941 gggtctgtta catgcatttg gtggacccct gctcaatcct atgtttgcag gtgcagccat
    21001 ggccctcagc tcagtgtccg tcgtcttgaa cgctctgcga ttgaaaacct acaaactata
    21061 tcaaaaatac cagtcaaaaa actggtattt ttttacataa acgcttacaa tgtatatatt
    21121 aagtgcaagg gagatgttta tgacaacctt tattggaaaa ccggtgacct tggtaggtcc
    21181 gcaattaaga gtgggggatg tagcccctga ttttgtcctc atggccaatg acttgagctt
    21241 gaaaagcctg aaagactttg gcaagcagac caaggtcatc agtgttgtgc cttctattga
    21301 tacagggatt tgtgataccc agacccgtcg cttcaatcag gaactggctg accgtgacaa
    21361 tacggttgtt attacggttt cagcagacct cccctttgcc caaaaacgct ggtgtggcgc
    21421 tgcaggtttg gaagatgcca tcaccctgtc tgattactat gaccatgcct ttggtaaatc
    21481 ctacggtgtg ctcatgcggg agtggaattt gctggcgcgt gcggtctttg tcctcaatgc
    21541 cgacaatgaa atcacctacg tagaatactt ggataatgtc aacgaacatc cagactatga
    21601 tgcggctttg gaggctgtta aataaagata taacggtgcc ggaacaggca tcgttttttg
    21661 atggaatatt tttgtctaat ttgatatact aaatttatca aaaacaagga gggtctttta
    21721 tggaaaagac acagattatt caagacgttt tggccctcat tcaagacttg aatcgggcct
    21781 ttcaagcaga taaagtagga acagctgatg aacaacggtt ccaacataat ctgacagaga
    21841 cgacacgcat attgtcggag gccaagtcgg ttaccaatac agaactgatt gcgattgaga
    21901 aattttatcg ttcgaccagt tttttggttg gactgggcga cctgcgattg agtgaaacca
    21961 gcaggcaggc ttggcgggca tttgaccgat attactacga aacgatcaga gaagaactca
    22021 aactctatgg cggctctgct attgcccaag tgtaaaagat gaaggagagg gtgaaaaccc
    22081 tcttttgtgc tataataagt agtaagaata cagtttttag gaagagaaga agcgaggtgt
    22141 atcatgtcct atatccaagt aaagaattcg tcaaaatact accaaatggg agatgcgacc
    22201 attgtggcca atgatggtgt gtcctttgag attgagcagg gtgagctggt catcattctg
    22261 ggttcatctg gtgcgggcaa atccactctg ctcaatatct taggtggcat ggacagcaac
    22321 gacgaggggg aggtttggat tgacggtgtg gatatcgcca agctgtcaag tcatgaactg
    22381 accaattatc gtagagatga tgtaggtttt gtatttcaat tttataactt ggttgccaat
    22441 ctgaccgcca aggaaaatgt ggaactggca gcagaaatcg tcaaggatgc cttggatgcc
    22501 gaggaggtct tggaacaggt cggactcggt caccgaatca ataatttccc tgctcagctt
    22561 tcaggcggtg aacaacaacg tgtggccatt gcccgtgctg ttgccaaaaa gcctaaaatt
    22621 ttgctttgcg atgaaccaac tggcgctctg gactaccaaa caggtaagca ggttttacaa
    22681 atcctacaag atatgtcccg caagcagggg gcaacggtga ttatcgtgac ccacaatagt
    22741 tccctagccc ctattgcaga cagggtcatt cggatgcggg atgcccgtgt gcactccgtt
    22801 gagttacacg cagaaccaca ggatattgca agcctagaat attagtgggt gaaactatga
    22861 aaaagaaaat ctactggaag gatatgagac aatctctgct ttcttccaag gggcgttttt
    22921 tgtccatatt tagcctgatg atgctaggag ctctagcttt gacaggtctg aaagtaacag
    22981 ctcccaatat ggaaaagacg gcccaagcct acatagccag tcatcgaacg atggatttgg
    23041 cagtaatttc aggtctggga cttagtcaag ctgaccttga cgaattagaa acgatagaag
    23101 gtgctactct tgaagcgggc tactttaaag atgtggttac taatgaaggt cagactgcaa
    23161 ttcggctgtt ttcagctccc aagaccctat cgacctataa actagtagaa ggggaagtgc
    23221 ccagccaaaa ggggcaaata gccctatcag cttctttcaa aaatcgttac aaattggacg
    23281 atactgttca agtgacggag tctgataagg atggaaaaat cttgacacag acaagtttta
    23341 ctcttgtggg ctttgtcgca tcagcagaaa tttgggacaa tgaaaccatg ggcatggctg
    23401 taagtggtga tgggcagtta ggtggctatg gccttgttag tcaggatacc ttcaaatcag
    23461 aagtttacac tattgcccgt attcgctatg atgatttggt tgatttacca tattacagtc
    23521 aggcctatca agacaggttg gaccagcacc aagaagactt agaaaagtta ttggctaaca
    23581 atgatgaaca acgattggca actattcagt cagatggaca gacagatatt tcaaaagggg
    23641 aagaggaaat tgctcaggct cagtcccagc ttgaacaggc agagtcagaa ctggaaacag
    23701 gggaggagca attagcgaca ggtcgcagtg agtttgcgcg tggtagggct aaggttgtcc
    23761 aaacggaagc tgaattacga gctgcccaag cccaactatt aaaaaataag tttgaattgg
    23821 aagaaagtaa aaaggaattg gacgggcgta aggctcaatt agaacagact gcttcatttc
    23881 tagacggcta tcagatggaa ttagaaatgt cagcccagca gttagaagag gccaagcaag
    23941 aattggattc ccaaaatgcc caactgagtc agaccgcatc tcagatttcc acagggcgag
    24001 ctagttggtt tcaagctcag caagagttag accttgaaat tgccaatcac ttgcaagaag
    24061 gtcaaaccct ctcagactat cctgacttgt tggccagaca ggaaggtttg gatgttgaga
    24121 aaagccgatt agaccaaatg gaatctgcac atgagcaggc caaccaagcc tatttacaag
    24181 gttatgatta ctatcaaacc aaacaaaatg aatacaatag caatctagcc cagtaccaaa
    24241 cttggaatca agaatatcag gcaggtttgg cccgttatca agcaggtttg agtcagtatg
    24301 aacaaggcat tgcagcctac aataaaggag tagaagacta tgaatgggga ctgagtcagt
    24361 tagagtcttc aaatcaactg ctccgtcagg aagaactccg tttggaggag gctgataaag
    24421 agttaagtca agctcaatcc caattttctg ataagaaagc tgtggccgat caagaaatta
    24481 gccaagctca aaccgagatt gctcaggcta aatccgactt aagtaagctg gcaaaagcgc
    24541 cctatcaggt ctatactcgt tcaagcctac caggtggaga tggctatact acctatagca
    24601 atgcgactag gtctattgct gcagtgggca atgtcttccc agttgttctc taccttgtcg
    24661 cagctctagt gacttttacc accatggccc gttttgtcga tgaagagcga acacagtcag
    24721 gtatcctcaa ggcccttggt tatacgaata gacagattat ggctaagttc attctctatg
    24781 gtttggcggc aggtctggta ggaacaatag tcggcataat agcaggtaat ctcctcttgt
    24841 ctccacttat ttccgacatt attacgcaga caactgtgat tggaccagct aaacttcatt
    24901 tttatcccct ttggacaggt ttagccttgc tcctatcttt ggtttcctcg gtcctgccag
    24961 cttacttggt ggctcgtcgg gagctgacag aaaaacctgc tcagctactt ttacctaagc
    25021 caccggtcac aggctccagc atttggcttg aaaaatggcc ggctatctgg tctcgtctga
    25081 gctttaccca taaggtgaca gcccgcaata tcttccgcta caagcttcgt atgcttatga
    25141 ccatctttgg agtagcaggg accgtcgccc ttctttttgg aggactgggt atccgttcct
    25201 ccatctcagg agttgtccaa cgacagtttg gggagctgat ccattatgat atgttggtgg
    25261 tggaaaatag cagagctact gaggaagagt tagataagtt aacacatttt cttcagtcag
    25321 atcaggttcg ccaatccttg ccagtggctt ttgaacagct caatcaaacg gtggaagaaa
    25381 acggtcagag aaagaattta tcgattagtc tctacatttc agaccgtcgg gattttggaa
    25441 atcaagtcag tctggaaagc tcgacaggtc agcctattaa actgagtgac agggggattg
    25501 tcctcacaga aaaattggcg caaatttacg gggtctcagt tggtgataag ttatcactga
    25561 ccttggaaga taaggaagtt tcagtcaggg tagaggctgt ggctgatatg tacgcagggc
    25621 attttatcta catgacagat agctactacg aacaagtgac cggcaagcag aagactgcca
    25681 atgcctattt ggttcaattg aaagacagtc agttggggca tattcagact cttgcaagtc
    25741 aactcctagc gatgccagca gtcagaagtt tggttcaaaa tacttctctt atagacatgc
    25801 ttaccacgat tgcaggctcg cttcagacca tcatgaccat tctagtcatc ctatccatct
    25861 tgctcggctt ggttattctt tacaacctta caattatcaa tatgtccgaa cggattcgtg
    25921 aattatccac catcaaggtg ctgggcttcc acaatagaga ggtgaccatg tacatctatc
    25981 gtgaaaccat tgccctttcg ctgattggta tgttggttgg actggttggc ggtatttatc
    26041 tccacaagct ccttcttgcc atgattggtt cggacagtat ccgcttcaat ccatctgtcg
    26101 gactagaagt ctatctcatt cctatcttag ccattagtgg aattttgtct gttcttggtt
    26161 ggtatgtcaa tcaccatctg agaaaggttg atatgctggt ggccttgaag tcggttgatt
    26221 aaaacagtct gggaatagac tgttttaacc cgagcctaaa aacacgaaag cggatagtct
    26281 gtattgtgaa ctaatttgaa atatgagaaa cacagctata aagcaaaaaa atcctagtgc
    26341 atctaggatt tttctgtaaa cacaagtcta gaagtgtgct ataatcatct catgaaaaaa
    26401 ataagtgatt taggattaac aggtcgaaaa ttagttggag aaggtctaat cttagtcttc
    26461 atcggtattg gatttttaat tgctggttgg caatttccag gactgattct tcgatttgtt
    26521 cacgcaggtc tattcttttt agctttatat gaattgagca tgacattttt cagaaagaag
    26581 aaatcaagtg aaagtgttat tgcgctagtt gggaaggctg ttcttttcgg gatcctagcc
    26641 agtctcgatt tagctgttca aattcccctc tatttcgcgg ctatttttgt tgggatttat
    26701 caacttttta cagctcttat caatttcatt actttttacc tatatcgaaa agatggggta
    26761 cagccacgga ttcgctattt aatagatgga atttggttat tcttactagg ttcagcttcc
    26821 ctatttgtgt caggcacaca gctggttgtt caaacaattg tcatcggagg ttatctgatc
    26881 ttgtatggac taactaatct gcgtgatggt ttcttgtttg aggaggcgat tgagcaacaa
    26941 aatcttaagc gccatgtccg tttgcctcta cctttatttt tagcagcttt gattcctcgt
    27001 atgaccctgc aaaaagtcaa tgattacttg gcggataatg agggacaaac ggctcaatct
    27061 atctataacc gccacaaaga aattgcggag cttccagcat tagaagtctt tgtgcatgta
    27121 ggtgaagagg gttttggggc tgttggacat gttgatttga gctataaggg acgagtgtat
    27181 ggttatggtt catacgatgt cctgtctgag cgtttgggtg gtgcgattgg tgatggagtc
    27241 ttgttcaaag cagagcgcca agcctatatt gacttctgta atcaagaagg aatgaccatg
    27301 ttaggttacc agctgagctt aagaccagag caagaagagg caatagaaac tcgattggct
    27361 gaaattgata atctgcttct tccttggaat ccaagtcctg aaaaagtatc gaaaacggta
    27421 gatgggcagc cgattgaaat gtatgcctat cgaatgaaag aggcaataca tgcggaatta
    27481 ttcaaattta gaaagtctaa atttaaaacc tatttcgtcc tatctactaa ttgcgttctt
    27541 ctggctgatt ctgtgattgg acaagctgga accgatatac ttggtatgca tggatttatc
    27601 gcacccggaa cctaccaatc ttatctggat caagaatttg aaaagccaca tagtttagta
    27661 gtcgcaaaga acatttatta tcgaaaagaa aaatcctagt cactgactgg gattttctgt
    27721 tattccagct ctctaagttc cacaaaactc ccccatccat gctataatag agacatgaaa
    27781 aaaaataaat tattattaat cgatggctct tctgtagcct tccgtgcctt ctttgcactc
    27841 tataaccaaa tcgaccgctt caagaatgcc aacggtctgc ataccaacgc catttacggc
    27901 ttcaatctca tgctggacca catgatgaag cggattgagc cgacccacat tcttgtggct
    27961 tttgatgctg gaaagaccac tttccgtacg gagatgtatg cagactataa ggcaggtcgt
    28021 gccaagactc cagacgaatt ccgtgagcag tttcctttta tccgtcagat gttggatgcc
    28081 atgggagtca agcattacga actggatcag tatgaggcag acgatattat cggtaccttg
    28141 gacaaaatgg cagagcggac agacatccct ttcgatgtga ccattgttag cggtgataag
    28201 gatttgatcc agctgactga tgagaacacc gtagtcgaaa tttccaagaa aggcgttgcc
    28261 gaattcgaag aatttacccc agcctacctc atggaaaaaa tggggattag ccctactcag
    28321 tttattgacc tcaaggcttt gatgggagat aagtccgata acattcctgg cgtgaccaaa
    28381 atcggtgaaa aaacaggtct aaaactcctg acagaatttg gttctttgga tggtatctac
    28441 gaaaacattg acagcatgaa ggcttctaag atgaaagaaa acctgattgc tgataaggag
    28501 aaggccttcc tatctcgtac acttgctacc attgatactc aggcaccaat cgaaattggt
    28561 ctggatgaca ttgtttatca aggccccaag gtggatgaac tgggacaatt ttatgatgac
    28621 atgggcttca aacaattaag ggctcagtta ggtacgacca gctcgcaaga ggaagcggtg
    28681 ctcgatttcc aaatcgtaac ggaaatcagc cccgctatgc tcaaacaaga ccagtttttc
    28741 tattttgaaa tcttgggtga aaattatcac cgagaggatt tggttggttt agcttgggga
    28801 gataaggaga aaatctatgt cggagggcct gagctacttg atagtccagt cttgcgtgac
    28861 tttttagaaa gccaaaccat aaaaacctat gactttaagc gtggaaaagt tcttctcgac
    28921 cgaaaagaga ttaagctacc tccagctact ttcgatagcc gtctagccaa atacttgctt
    28981 tccaccgttg aggacaattc cctaacaacc attgccaacc tctatggtca gaccagtctt
    29041 gttccagatg aggcagttta tggcaagggt gctaagttag acttgccaga acgcgagatc
    29101 tttttcccac acttggcacg taaggttcag gttttgattg agacagaaga gccgatgttg
    29161 accaaattag aagaaaatca gcaattagat cttttgtttg acatggagtt gccactagca
    29221 aatgttttag ctaagatgga aattgctggt attaaagtgg aagctgagac tctcaaagct
    29281 atgcaatctg aaaacgaagt tttgattgac cagttgacca aggaaatcta tgaactagct
    29341 ggtcaggaat ttaatatcaa ttcgcctaag cagcttggga ccattctctt tgaagatatg
    29401 ggactaccat tggaatatac caagaaaacc aagacaggct attcaacagc agtagatgtc
    29461 ttagaacgat tagcgccaat tgcaccagtt gtttcaaaaa tcttggaata ccgtcagatt
    29521 accaagcttc aatcaactta tgtagtcggc ttgcaggatg ccattttaga agatggtaag
    29581 atccataccc gctatgtaca ggatttgaca caaacaggtc gtctatcttc aacggaccct
    29641 aacttgcaaa atattcctgt tcgtctagaa caagggcgct tgattcgtaa ggcatttgtg
    29701 ccatcgcttg aaaatagtgt ccttttggca tcggactatt cacagattga attgcgcgtc
    29761 ttggctcata tttctcagga ccagcatttg attgaggcct tccagcaagg tgcagatatt
    29821 cacacttcga cagctatgcg ggtcttcggt atcgaaaaag ctgagtatgt gacaccaaat
    29881 gaccgtcgga atgccaaggc tgtaaacttc ggtgtcgtct atggtatttc agatttcggt
    29941 ttatctaata acttggggat tacacgtaag gaagctaaag cctatatcga tacctatttt
    30001 gaacgcttcc caggaattaa gaattacatg gaaaccattg ttcgtgaggc acgtgataag
    30061 gggtatgtag agacgattta caaacgccgt cgtgaattac cagatataaa ctctcgcaat
    30121 ttcaatgtcc gtaattttgc ggaacgaaca gccatcaact caccaattca aggttcggcc
    30181 gcagatattc tcaaagtagc catgattaat ctcgacaagg ctttgactga agcaggtctt
    30241 gcgacacgta tgttattgca agtacacgat gagattgttt tggaagtccc agtggcagag
    30301 ctagaaacgg taaaagccat ggtaaaagag actatggaat cggcgattag cctgtctgta
    30361 ccattgattg cggatgaaaa tgaaggttca acatggtatg aagcaaagta agaaaggaaa
    30421 aagtatgaaa aaattaattc tttgtattgg tctatgtagt cttctacttg caggttgcgg
    30481 aaaagcatcg cagaagactg agaaaacacc agcttcttca ggggaagagt tttcaaccac
    30541 cttaccgatt ttgcaagaaa aacaggatac tacgaacgaa cagttcaatg ttttagcaaa
    30601 tgcagaggtt gtagctgtta atagtacacc acctgccgac gaaacacaaa aaggccacaa
    30661 gatttatgcg gccaataatg gtgttgctga aaaagatgaa aatgggaata tcaaggaata
    30721 tttccgttat tatgatgtgc catctacttg gacaattaat gcagaaaata ctaaggatga
    30781 gacggtcgct gcagtctacg atgttaaaga ggggggaagc aattacatgg ttcaaatcta
    30841 taatatcaat gcttttaatc agtctccatt ggaagacggt cgcaatatga cgccggagga
    30901 attagaagca cggatggttg aaacaaatca ttctttcagt gaaaagacgg ttgtcacaat
    30961 caatggtcag gaatggcagg ttgggcgaca gttattaaca gatcaaaaat tagctcgtct
    31021 gactttttat cggatggaat caacagctgc ttatgatgac tccgtggttg tgggttcaat
    31081 ctattattcc ttagatccag gagatgataa aaagcgtacc aatcttaaaa aggttatcgg
    31141 ccaagttaag gatgttgtgt accaaattgc taaaaaataa tcaaggtaga caagctataa
    31201 tcagtaacga gttaaaactg acaagattgt gttatagcac accttattca ttaagctttt
    31261 attgattcta acatttaata tacattaaag gaggtctcta tgtcttattc cttccaaaat
    31321 cctagtcagg acattatctt tgactatctg aaaaatgcta agaccattgc agtggtcggt
    31381 ttgtctagtc gagaagagac ggcagcctac cgcgtttcca agctcatgca ggaagcgggc
    31441 tataaaatta ttccagttaa tcccaaggct gctggtggga ctattttagg cgagttggtc
    31501 tatagtagtc tagcagagat tgaccaacct attgatattg tagatgtttt ccgcagaagt
    31561 gaatttttac cagaggtagc acaggaattt atccagtcga acgccaaagt tttctgggct
    31621 caactcggtt tagaaagcca agaagcagaa aaacaattgc gtcaggcagg tcgtaacgat
    31681 attgtcatga ataaatgtat caagattgaa tatcttgaaa tgaaagaaca atactaataa
    31741 gtcgggtata tttatccgac ttttttcatc gaaaaagcag ctcaatgaac cattgaactg
    31801 ccggatgact ctaaggagga gcacttagaa ttggaataaa ttactacaca tggcgtaaaa
    31861 aatagaaagg aagaaatctg ctccaatacc aagcaggcta aaatagtcct ttgtcgctcc
    31921 tcagtcatag tataacacaa tccaaatgtt tgtaccaatt attactatat tttttttctt
    31981 aaatatagac ataaaagcgt atataaaaat aagagcaaat atcgctctta ttttatacgt
    32041 aactcatttt cttagcctga tcatctaaaa tttcttcatg gaagtgcatt tgtgcagcat
    32101 agtgatacgg ccatacatat aaaccagcca ggccaaatgt aataatgaca agaaggaacc
    32161 agccgatgaa ggataaatca agtgtaaagc gtttaaactt gtaacctttc atcaactttc
    32221 gactagattt aatgattgaa aaggcacctg tatattcttc gcgttccaat tgttcaaaca
    32281 agatatattc tacctgtgag taagcataga tttgtggaat ataaagagca attcctaaaa
    32341 ccataagtag gatacctccc atggccatta gccctagtat ggcaaggatt tccataggaa
    32401 gtgcatcagg gtctaaggat tgactggatg cagctataat cgtaatcatc gttccagcac
    32461 cgataagtag accgatacca aggtaaaaca gtagtcccca aaggaagagc aagaaacttt
    32521 ttaaaatgta agttcgaaag attttccaga aatctttatg attgaaaatg ctcaaggaat
    32581 ctttgaatga tgtggtagtt ttgccccctt tgatgatatt gaagatagtc catatgactg
    32641 ataatgacaa cattcctagt agcaatccgt aaaatactgg aaacaaagag gtagaaataa
    32701 agtagctcgg actagcaagt tcctcagccg acactccagc aaggctattg cgagagaaag
    32761 aaattaactg aacgataaca gaaatagtga cggggatgac ggccacttga tagataccag
    32821 gtgtctcgtt tagcgtttgg cgagcccgct cacgtatatt agaaattgta aacatctaca
    32881 taacctcctt acccaacatt gtaacataat tctagatgac aagctaggct ttttttgata
    32941 gactagaagg tgctgtggga atttgtcagt ttgttgtgat gcgcctatct atttactatt
    33001 aaataagtag aagaaaaggc aaatatcact gaaataagcg agaacattaa agacattctg
    33061 atagattaga ccatgcaaga ttgagaaact gtatttccag gtaaagtgct tttatggatg
    33121 gtatgaaaga gctgaactgt gaatccagaa ctaatatcct aggactgttt ttcctagcgg
    33181 gaggtaaata aaacatgaca gatgttccaa tcaagtatcg cttgattaag aaagaaaagc
    33241 acacaggtgc acgtttgggc gaaatcatta ccccacacgg gacctttcca acccccatgt
    33301 ttatgccagt tggaactcag gcaacggtaa aaaccatgtc gcctgaagaa ttgaaagcga
    33361 tgggttcagg aattatccta tctaatacct atcatttgtg gcttcgtcca ggtgacgaat
    33421 tggtggcgcg tgcaggtggt ttgcataaat ttatgaattg ggatcaaccg attttgactg
    33481 actcaggtgg tttccaggtt tattctttgg cggatagtcg caatatctca gaagaaggtg
    33541 tgaccttcaa aaaccatctc aatggtagta aaatgttctt gtcacctgaa aaagctatct
    33601 caattcagaa taatcttggt tcggatatta tgatgagctt tgatgagtgt ccgcagttct
    33661 accagcctta tgactatgta aaaaaatcca tcgaaagaac aagtcgttgg gcagaacgtg
    33721 gtctcaaggc tcaccgccgt ccgcatgacc aaggtttatt tggtattgtc caaggtgctg
    33781 gttttgaaga tcttcgtcgc caatcagccc atgatttggt tagcatggat tttccaggat
    33841 actctattgg aggattggct gttggtgaaa cacatgatga aatgaatgct gtactggact
    33901 tcacgacccc tcttttaccg gagaataaac cacgctatct catgggtgtt ggagcaccag
    33961 atagcttgat tgatggcgta attcgtgggg ttgatatgtt tgactgtgta ttaccaacac
    34021 gtattgcgcg taatggaacc tgtatgacca atcgtggacg tcttgtagtg aaaaatgccc
    34081 agttcgctga ggactttaca ccgttagatc cagagtgcga ttgctacaca tgtaaaaact
    34141 atacacgtgc gtatctccgc catttactta aggccgacga gacgtttggt attcgtttga
    34201 caagttatca caacctctac ttcttgatta atttgatgaa aaatgtccgt caagcaatca
    34261 tggatgacaa ccttttggaa ttccgtcaag actttatgga aaaatacggt tacggtaaaa
    34321 acggcagaaa tttctagaat aaacaacctc ctacagattt gtaggaggct attttttatc
    34381 cttcaaaata cagtaattct tttggtgttt ttgtaaagac ttcaaagcca tttttggtaa
    34441 cgtaaccaca atcctcgata cgaacaccaa cttttccagg gatgtaaata cctggttcga
    34501 cagagaaaca cataccttct tcgatgacca aatcattgcc ttccataatc gatgggaatt
    34561 catggacact cattcccaaa ccgtgaccga gtcggtggtt gaagtactcg ccataacctg
    34621 ctttttcaat cacagagcga gcggcatagt caatctcgcc agcagtcaca ccaggcttaa
    34681 tcatattgac agctgccatg tgagcctcca gagtcaagtt gtaaatatct tttttaaact
    34741 gatcgggttt accgacagcg acagtccgtg tcatatcaga cgtatagccc aaagcttcca
    34801 cgcctaggtc gaacaatagc agagcgttat tctcgatttt gtttgttgag ggaataccat
    34861 gtggatttgc ggcattgtca cctgttaaga ccatggtctc aaagctcatt tttgagatgc
    34921 cttgcttttt catttcaaat tcaatctgag caataatatc agtttcagtt acatcgagtg
    34981 agatgttatt gaaaccaacc tgcatagcct tatctgcaaa ctctccagca accagcattt
    35041 tttcaatttc atcacgagac ttgatcaatt tcatagtatt aatcagaggt gtaatgtctg
    35101 aaaatggttg gctaaagata gactgaagac catggtagcg ggttaaattc aaattatcaa
    35161 attctgcaca gattgctgag aaagattttt gtggcaattt gctcttgata atctgccatg
    35221 gattttctga gtccatatag ccggctacag gaaaatcaac agtcgcaacc gcacgctcta
    35281 catccaaggc agggagaaag agtagtgagt cgtggtcagg cataacaaag agcatcatgt
    35341 ggcgttcatg aggatcacta tgatagccag tcagataata gatgctaact ggatcagaga
    35401 agatggccaa gtccattttg ttggcttcta agtaggattt aacatgatgt aattttgaca
    35461 tagtggagac ctttctagca tgtagtggta aaaaaagtga aa
//
LOCUS       DBNFCO010000011        34253 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.011, whole genome shotgun sequence.
ACCESSION   DBNFCO010000011 DBNFCO010000000
VERSION     DBNFCO010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 34253)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34253)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34253
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.011"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(<1..912)
                     /gene="coaA"
                     /locus_tag="AC1PIV_000466"
     CDS             complement(<1..912)
                     /gene="coaA"
                     /locus_tag="AC1PIV_000466"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009568566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004594 - pantothenate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HIP6611516.1"
                     /translation="MKNEFLNFEQIDRATWQQLHRKTTIPLSQSELNSIKSFNDRIQL
                     HEVSDIYLPLVNLIHIYRKARKDLNFTKSLFLQKTIKPQPFIIGVSGSVAVGKSTTSR
                     LLQILIARTFKYAKVELVTTDGFLQPNAVLEERQLLNKKGFPESYDMEKLIDFLDKIK
                     NGYDCQIPVYSHEIYDIIPNKTQEIKSPDFLIVEGINVFQNPQNQRLYVSDYFDLSIY
                     VDADVEHIETWYLERFQKLLTLAKNDPNNYYHRFTQMTYPEILSIAQNTWKNINLANL
                     EKFIEPTRNRADIILHKAENHEIDKIYL"
     gene            1021..1611
                     /locus_tag="AC1PIV_000467"
     CDS             1021..1611
                     /locus_tag="AC1PIV_000467"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HIP6611517.1"
                     /translation="MSNMYYEKNPTIAHDIHEIHVNLLDTPMSFMTDAGVFSKKMVDY
                     GSQVLLKNLYFEKGASVLDVGCGYGPIGLTLAKVFSTKTTLIDINSRALDLATKNAER
                     NGVIAKIYQSNIYENVDETFNHIVSNPPIRAGKSVVHEVIAGAFQRLKAHGTLSIVIQ
                     KKQGAPSAKAKMEEVFGNCQIIKKDKGYYILESVKE"
     gene            1608..2885
                     /locus_tag="AC1PIV_000468"
     CDS             1608..2885
                     /locus_tag="AC1PIV_000468"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018543466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016154 - pyrimidine-nucleoside
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0006213 - pyrimidine nucleoside metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HIP6611518.1"
                     /translation="MRAVDLIQKKRDGLELSSEEIKWLIDGYVAGTVPDYQMSALAMA
                     IYFKGMSTREISDLTMSMVATGEQIDLSAIPGIKVDKHSTGGVGDKVTLILAPLVASF
                     DIPVAKMSGRGLGHTGGTLDKLESIKGYQIEVSQADFIKQVQDTGVAVIGQSDNLVKA
                     DKLLYALRDVTATVDIIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVEEARVLA
                     QTMVDLGKAVGRKTVAVLTDMSQPVGTSIGNRLEILEAIEILQGKGREDVTEFICELA
                     QIMLGLANVEKSIEEVRQHIDNGAALKKFEEMVRAQGGDLEDLYRPVQVTQQVPVLAE
                     EDGYIVGLPALEFGLFAMKLGAGRAVKTDNLDYETGIVFHKKVGEAVSKGEQIATIYA
                     NENISENMLTNFQKNVKIDKESVKTKEIIEIIS"
     gene            2901..3563
                     /gene="deoC"
                     /locus_tag="AC1PIV_000469"
     CDS             2901..3563
                     /gene="deoC"
                     /locus_tag="AC1PIV_000469"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HIP6611519.1"
                     /translation="MKLNKYIDHTILKPETTQEQVEKILAEAKEYDFASVCVNPTWVA
                     LAAESLKDSDVKVCTVIGFPLGANTPAVKAFETKDAISNGADEIDVVINIGALKTGNY
                     DLVLEDIKAVVAASGDKLVKVIIEACLLTDDEKVKACQLSQEAGADYVKTSTGFSTGG
                     ATVADVALMRKTVGPDMGVKASGGARSYEDAIAFIEAGASRIGASSGVAIMNGAQADG
                     DY"
     gene            3550..3939
                     /locus_tag="AC1PIV_000470"
     CDS             3550..3939
                     /locus_tag="AC1PIV_000470"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HIP6611520.1"
                     /translation="METIDLIELAVKNSQKAYVPYSKFPVSAVLVAKTGEIFTGVNIE
                     NASFGLTNCAERTAIFKAISEGVKDFSEIIIYGKTEKPISPCGACRQVMAEFFDKDLK
                     VTLVAKDKSTVETTVGELLPYSFTDLT"
     gene            4020..5087
                     /locus_tag="AC1PIV_000471"
     CDS             4020..5087
                     /locus_tag="AC1PIV_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family lipoprotein"
                     /protein_id="HIP6611521.1"
                     /translation="MNKKLVGLGLAAAAAVSLAACGNRASKSSSSEASSSADTSVKAA
                     IVTDIGGVDDRSFNQSAWEGLQEWGKAASLSKGNGYDYFQSASESDYITNLDSAVAGG
                     YNLVFGIGFALESAIAEVAPNNPNTHYVIVDSVVPDQDNVVSVGFADHEASYLAGVAA
                     AKSTKTNHVGFIGGMEGVIIDRFEAGFVAGAKSVNKDIKITVDYAGSFGDAAKGQTLA
                     AAQYAAGADVIFHASGGTGNGVFAAAKAENETRNEADKVWVIGVDRDQSAEGTYTSKD
                     GKSSNFVLASTLKQVGTSVKDIATKAAAGDFPGGQVLQFSLKDKGVELAETNLSEDAS
                     KAVADAKQAILDGKVEVPEKP"
     gene            5282..6817
                     /locus_tag="AC1PIV_000472"
     CDS             5282..6817
                     /locus_tag="AC1PIV_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIP6611522.1"
                     /translation="MTKDYVIEMRNITKIFGEFVANDHINLNVRRGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIVINGQSVKIDSPSKAAQLGIGMVHQHFMLVDAFTVAENI
                     ILGSETTKGGVIDLKKAIAEIKELSAKYGLEVDPTAKVADISVGAQQRVEILKTLYRG
                     ADLLIFDEPTAVLTPAEIAELLKIMKALVEEGKSIILITHKLDEIRAVADSVTVIRRG
                     KSIETVAVEGATNQDLAEWMVGRSVSFKTEKVEASPKEVILSIKDLVVNENRGIPAVK
                     GLSLDVRAGEVVGIAGIDGNGQSELIQAITGLRKVKSGSITIKGEEVVGKTPRKITEM
                     QVSHVPEDRHRDGLVLPMTVAENFALQTYYKEPISKNGILNYNIINEKARALMEEFDV
                     RGASELVPIKALSGGNQQKAIIAREIDRNPDLFIVSQPTRGLDVGAIEYIRKRLIAER
                     DKGKAVLVVSFELDEILDVSDRIAVIHDGVIHGIVEPAKTNKQELGVLMAGGHIEKGE
                     EHA"
     gene            6810..7871
                     /locus_tag="AC1PIV_000473"
     CDS             6810..7871
                     /locus_tag="AC1PIV_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIP6611523.1"
                     /translation="MLNKYKNLALPLMAVVSGILLGAIVMLVFGYDPIWGYEELFYSA
                     FGNIKSIGEIFRAMAPLVFTALGFAVASRAGFFNVGLSGQAYVGWVFAGWFALANPDL
                     PRPVLILGTVLIAMLAGGIAGAIPGILRAYLGTSEVIVTIMMNYILLYSCNYIIRDVF
                     ADSLMKNTDSTVNVSANASYQTEWLRALTDNSRMNIGIFFAIIAVFVIWFLLTKTTLG
                     FEIRSVGLNPTASDYAGMSAKRTIILSMIISGALAGLGGAIQGLGTFQNVYIQSGNLD
                     IGFNGMSVALLASNSPLGIPLAAFLFGVLSVGAPGMVRAQIPPELINVVTASIIFFIG
                     VKFIFEQLLKSRNKAKGAK"
     gene            7873..8826
                     /locus_tag="AC1PIV_000474"
     CDS             7873..8826
                     /locus_tag="AC1PIV_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIP6611524.1"
                     /translation="MNVSILALLISQMLIYSAPLIFTSLGGVFSERGGIVNVGLEGIM
                     VIGAFAGVVFNIEFAGTFGNATPLLAVIVGGLAGVVFAAIHAMATINFRADHVVSGTV
                     LNLLAPALGVFLVKVIYNKGQTDSITESFGKFSFPILADIPIIGEIFFKNTSLMGYVA
                     IATAFLAWFILYKTKFGLRLRSVGEHPQAADTLGINVYAMRYAGVLIAGFLGGVGGAV
                     SAQSVNINFSATTIVGSGFIALAAVIFGKWNPIGAMLASLFFGLSQSLAVVGGQLPGL
                     KDIPTVYLQIAPYLITVIALSAFFGKAVAPKTDGINYIKSK"
     gene            8982..9512
                     /locus_tag="AC1PIV_000475"
                     /pseudo
     CDS             8982..9512
                     /locus_tag="AC1PIV_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940825.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0046654 - tetrahydrofolate biosynthetic
                     process [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
     gene            complement(9555..10538)
                     /locus_tag="AC1PIV_000476"
     CDS             complement(9555..10538)
                     /locus_tag="AC1PIV_000476"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HIP6611525.1"
                     /translation="MTATKQHKKVILVGDGAVGSAYAYALVNQGIGQELGIIDINKDR
                     TQGDAEDLSHALAFTFPKKIYSAEYSDAHDADLVVLTAGLPQKPGETRLELVEKNLRI
                     NQQIVTEIVNSGFNGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQAL
                     AEKIGIDARSVHAYIMGEHGDSEFAVWSHANVAGVKLYDWLQDNRDIDEQGLVDLFVS
                     VRDAAYSIINKKGATYYGIGVALARITKAIFDDENAVLPLSVYQAGQYEGVEDVFIGQ
                     PAIIGAHGIVRPVNIPLSDAELQKMQASAKQLKDIIDDAFANPEIAAGVKN"
     gene            10727..13171
                     /gene="gyrA"
                     /locus_tag="AC1PIV_000477"
     CDS             10727..13171
                     /gene="gyrA"
                     /locus_tag="AC1PIV_000477"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HIP6611526.1"
                     /translation="MQDKNLVTVNLTNEMKSSFIDYAMSVIVSRALPDVRDGLKPVHR
                     RILYGMNELGITPDKPHKKSARITGDVMGKYHPHGDSAIYEAMVRMAQWWSYRHMLVD
                     GHGNFGSMDGDGAAAQRYTEARMSKIALEMLRDINKNTVNFADNYDASEREPEVLPAR
                     FPNLLVNGTTGIAVGMATNIPPHNLGETIEAVKLVMDNPEVTTREIMEVLPGPDFPTG
                     ALVMGKSGIHRAYETGKGSIVLRSRTEIEEYGNGRERIVVTEFPYMVNKSKVQEHIVK
                     LVQEKRIEGITAVRDESNREGVRFVIEVRRDASANVILNNLFKQTQLQTNFSFNMLAI
                     QNGVPKILSVRQILESYIEHQKEVVTRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRNSETDAIAQAELMEKFDLSERQSQAILDMRLRRLTGLERDKIQSEYDELVALIAD
                     LADILAKPERVVQIIKDELEEVKRKYADPRRTELMVGEVLSLEDEDLIEETDVLITLS
                     NQGYIKRLAQDEFQAQKRGGRGVQGTGVKDDDFVRELVSTSTHDRLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLEENEAIQTIINVTKDQEADSYLFFATRQGVVKRTS
                     VSEFANIRQSGLKALNLKEDDELINVFLTNGQADIIMGTKFGYSVRFTETDVRNMGRT
                     ATGVRGINLREGDQLVGATMISDDQEVLVLTEKGFGKRTPASEYPTKGRGGKGIKTLK
                     VADKNGSLAGLTTVSGDEDIMVITDTGVIIRTSVANISQTGRSTMGVKVMRLNGEAKI
                     MTFALVDAAEIKEEKE"
     gene            13178..13927
                     /locus_tag="AC1PIV_000478"
     CDS             13178..13927
                     /locus_tag="AC1PIV_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HIP6611527.1"
                     /translation="MSKRENKKKRKGSFWRNLLTVVLILISLALIFNTSIRNFIIGWN
                     TNKYQISNVTTEDIEKNKQAETTFDFEQVQSISTEAILAAQWDAQRLPVIGGIAVPEL
                     GINLPIFKGVFNTSLMYGAGTMKENQEMGKGNYALASHHIFGVTGAADVLFSPLDRAK
                     NGMKIYITDKTNVYTYVIDSVEIVSPESVYVIDDVEGRTEVTLVTCTDYYATQRIVVK
                     GVLESTTPYNETAKDILDSFNKSYNQYDYGQ"
     gene            14040..14720
                     /gene="radC"
                     /locus_tag="AC1PIV_000479"
     CDS             14040..14720
                     /gene="radC"
                     /locus_tag="AC1PIV_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RadC family protein"
                     /protein_id="HIP6611528.1"
                     /translation="MYQIEFKEEAFLPRERLVEVGAERLSNQELLAIFIRTGTKKEPV
                     SILSNKLLNRLESLAALRELSIEELQSLTGIGRVKAIEIKAMIELGKRINQSELLLNE
                     RILGSEKLGRKMIHEIGHKKQEHLVALYLNTQNQIISQKTIFIGSVNRSIAEPREILH
                     YAVKCMATSIIIVHNHPSGSVQPSRNDLLFTENLKESCEKLGLVLLDHLIVGNKDYYS
                     FREESELF"
     gene            complement(14717..15409)
                     /locus_tag="AC1PIV_000480"
     CDS             complement(14717..15409)
                     /locus_tag="AC1PIV_000480"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0016811 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds, in linear amides
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HIP6611529.1"
                     /translation="MKKPVIGISGNEYKTGDHTEPLLSYTQTCLVQAIEDAGGLPLIL
                     PATEPDLAKYYIHLIDKLILTGGQNVQPSYYHEERTIDSDNYLPKRDEFELALIRAAQ
                     ENQKPIFGICRGLQLYNVAQGGSLHQSISEHWQDIDGQEVSQTIQLTQNSPLYDIYES
                     DPSVNSFHRQAIKDLAPDLEIIALSDNQQIIEAVHSAYPTKFLGVQWHPELLYGKREI
                     EKDLFHYIVNKL"
     gene            complement(15413..16051)
                     /locus_tag="AC1PIV_000481"
     CDS             complement(15413..16051)
                     /locus_tag="AC1PIV_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HIP6611530.1"
                     /translation="MKNDKKSDIPRATAKRLSLYYRIFKRFYAGNIEKASSKEIAEAI
                     GIDSATVRRDFSYFGELGRRGFGYNVKELMDFFADILNDTSITNVMLVGVGNMGRALL
                     HYRFHERNKMKIVMAFEADDNPAVGTTDENIPIHAISEIKERISEANSQTAILTVPSV
                     KAQEVTDILVEAGVKGILSFSPVNLSVPKDVVVQYVDLTSELQTLLYFMRKG"
     gene            complement(16186..16389)
                     /locus_tag="AC1PIV_000482"
     CDS             complement(16186..16389)
                     /locus_tag="AC1PIV_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HIP6611531.1"
                     /translation="MIEIHYLDAYKQERIQTFENKDAAILAFSGCLTLPDYYPVTSIT
                     QNGQALDYKGTIGDLYRYLQTLD"
     gene            complement(16391..16735)
                     /locus_tag="AC1PIV_000483"
     CDS             complement(16391..16735)
                     /locus_tag="AC1PIV_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HIP6611532.1"
                     /translation="MAFQQSVTLKDCNFTYHISPAIKKYTLRDNTFEQTKAGHYQLTR
                     LLEEIPNSNQGFLLKIIINQDLTGFKINITDKSGLHLVNIFKPESNKVIQEKFYFLMD
                     SLIDRDIFTKES"
     gene            complement(16737..17852)
                     /locus_tag="AC1PIV_000484"
     CDS             complement(16737..17852)
                     /locus_tag="AC1PIV_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HIP6611533.1"
                     /translation="MIYLDNAATTALSPTALQRMMEVAQENYGNPSSIHQSGRKANQC
                     LRQSRQEIAQILSASPEQIIFTSGGSEADTLAIQGYALAHQSKGKHLITTAIEHHAVL
                     HTMQYLEDRFGFEVTYIQPVNQVITAQQILDALRPDTILVSVMFANNETGQLLPIKEI
                     GELLADHQAVFHVDAVQAIGKIAISPSDYGIDLLAASAHKFHGPKGMGFLYSKVHKFD
                     SLIHGGKQEQQHRAGTENLPAIAAMATALTEQYESLDTHHQHVSELRQHIIEGLSGLD
                     YYLNQAGPHLPHVLNIGFLGKLNEQLLMQLDLAGIAVSSGSACTAGVVQNSHVLEAMY
                     GKDSHRLKESIRISLSEINTKEEIDTLIIELKKILGG"
     gene            complement(17863..18840)
                     /locus_tag="AC1PIV_000485"
     CDS             complement(17863..18840)
                     /locus_tag="AC1PIV_000485"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HIP6611534.1"
                     /translation="MVQPLGEHNIKLFSLNSNRDIAEKIADSAGIPLGKLSSRQFSDG
                     EIQINIEESVRGVDVYIIQSTSYPVNNHLWELLIMIDACKRASANTITAVIPYFGYAR
                     QDRTASPREPITAKLVANMLVKAGVDRVLTLDLHASQIQGFFDIPVDNLLTEPLFAAY
                     YMEKGLCGEDVVIVSPKNSGIKRARNIAEFLNAPIAIIDYAQDDSERSEGYIIGDVAG
                     KKAILVDDILNTGRTFSQASKIVQEGGATEIYAVASHGLFAGTAAQLLDEAPIKEILV
                     TDSVASKEQHPKNIAFLTASDLIADAIHRIQEHQPLSPLFKFTSPEKEN"
     gene            complement(18985..19551)
                     /locus_tag="AC1PIV_000486"
     CDS             complement(18985..19551)
                     /locus_tag="AC1PIV_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HIP6611535.1"
                     /translation="MKNHLEIEYKTLLTKSEYKRLLTDFSDVSPILQTNHYIDTPDLD
                     MKNHRFSLRIRTFEDSAELTLKIPQEVGNQEYNQVLDIQTAHDLLENFQLPAGQISDI
                     ISATEIPLDKLAVWGILTTKRYEKQTSIGLMALDENDYVGQKDYELEVEVTDADAGKI
                     LFDEFLKKKSIQFKYASSKVARTAAHMK"
     gene            19638..20309
                     /locus_tag="AC1PIV_000487"
     CDS             19638..20309
                     /locus_tag="AC1PIV_000487"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008728 - GTP diphosphokinase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HIP6611536.1"
                     /translation="MDFNWEEFLDPYIQTVGELKIKLRGIRKQYRKANRHSPIEFVTG
                     RVKPIESIKEKMALRHIKLENLAQDMQDIAGLRIMVQFVDDIEEVLAILRKRKDMQIV
                     HERDYINNMKASGYRSYHVVIEYPVDTINGNETVLAEIQIRTLSMNFWATIEHSLNYK
                     YKGNFPEEIKKRLEVTAKIAYELDEDMRKIRNDIQEAQALFDPAYRKLNDGVGNSDDT
                     DEEYR"
     gene            20293..21111
                     /locus_tag="AC1PIV_000488"
     CDS             20293..21111
                     /locus_tag="AC1PIV_000488"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006741 - NADP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HIP6611537.1"
                     /translation="MKNTGRKKIALLASRNPKSEAVSKELWTKLKEANFILTPKNPDI
                     VISIGGDGMLLSAFHKYEKLIDRVRFVGIHTGHLGFYTDYRDFEVDKLIENLKLDTGA
                     RVSYPILNVKIKMTDGRIVEARALNEATVKRLSKTMVADIIINNVPFERFRGDGISVS
                     TPTGSTAYNKSLGGAVLHPTIEALQIAEVASLNNRVYRTLGSSVVVPKKDKIVIEPKH
                     SDRYSIAVDNKTFVYDSIESIEYQIDNSKIHFVATPSHTSFWNRVKDAFIGEVE"
     gene            21111..22004
                     /locus_tag="AC1PIV_000489"
     CDS             21111..22004
                     /locus_tag="AC1PIV_000489"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HIP6611538.1"
                     /translation="MRFEFIADQHTKIKTFLKKHGVSKDLLAKIKYTGGNIWVNDIEQ
                     NATYLLDIGDRVTIDIPAEEDLTGSLKPIFFPLDIVYEDDHFLAINKPVGYASIPSAL
                     HSSTIANFVKGYLIEQNYENKQVHIVTRLDRDTSGVMLFAKHGYAHARLDKQLQAKLI
                     HKRYYALVKGNGQLEETGDIIAPIGRPEDSIITRCVTKNGKYAHTSYRVVQSWGDIHL
                     VDIQLHTGRTHQIRVHFSHIGFPLLGDDMYGGSLECGIERQALHCHNLAFDNPFSAER
                     IDLEAPLPEDFQAVINQLISK"
     gene            22022..22996
                     /gene="pta"
                     /locus_tag="AC1PIV_000490"
     CDS             22022..22996
                     /gene="pta"
                     /locus_tag="AC1PIV_000490"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016407 - acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HIP6611539.1"
                     /translation="MKIFEQLATKLEGKKVRIVLPEGEEPRILQATKRLVNESDVVPV
                     LLGNPDRIKIYLDIEGITEGFEIIDPAHYDRYDEMVAALVERRKGKVSEEQAHELLKD
                     VNYFGVMLVYMGVVEGMVSGAIHSTASTVRPALQIIKTEPGVSKTSGAFLMVKGEERY
                     IFGDCAINIDPDAQTLAEIAINSARTAKMFGIDPKVAMLSYSTKGSGSGPKVDKVVEA
                     TKIAQKLRPELDLDGELQFDAAFVPATGKLKAPGSSVAGQATVFIFPGISAGNIGYKI
                     AERMGGFAAVGPVLQGLNQPVNDLSRGCNPDDVYNLTLITAVQALEHR"
     gene            22998..24737
                     /locus_tag="AC1PIV_000491"
     CDS             22998..24737
                     /locus_tag="AC1PIV_000491"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIP6611540.1"
                     /translation="MKFLSRYFKDYIKESILGPVFKLLEACFELLVPLIIAYIVDTII
                     PNGSQGNLVAMLFLLVGIACIGIIVSLIAQYYSAKAAVGVTKELTNDLYQKVLSLPKS
                     SRDILSSSSLLTRLTSDTLQIQTGINTFLRLFLRAPIVVFGSLIMAFYISPSLSAYFL
                     GMIILLIFIVTVISVMTSRIYQSMRKELDGLVGQVRETVTGWRVIRAYGQREREIKAF
                     QGINQIYKKQQLQAGFWSSLLSPLTFLVVNSTLLILIWQGNIAISHNLLEQGMLVALI
                     NYLLQILVELVKMIMVVSTLNQTYISAQRIQEVFDQTSEDVESSLPKVVSEDKEIIFS
                     VRHLSFSYPKSAEESLSDITFDLRKEQFMGIIGGTGSGKSTLVDLLQALYSVPTNQLS
                     LFIDGKSPKNLKEWRQRIAIVPQQAQLFAGTIRSNLSLGLEEISDSDLWSALEIAQAK
                     SFIEDKGGLDSPVEAFGKNFSSGQRQRLTIARAILQKAPILILDDATSALDYLTESRL
                     LAAIRQELPGQNLIMVSQRTNSLRTADQILVLEQGRQVGLGRHEDLLRSSAIYQEIHQ
                     SQQQGEEDSYETI"
     gene            24724..26466
                     /locus_tag="AC1PIV_000492"
     CDS             24724..26466
                     /locus_tag="AC1PIV_000492"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIP6611541.1"
                     /translation="MRQSSFKELVRLVLHQPLRMSLMLVGTLVQVLLTVYLPILIGQA
                     VDAVLIANGQVLLGILGKMVMVILLNTLVQWYLPLVTNRLVYGMVADLREQVYVKLHQ
                     MPLSYLDRQSVGDLVARFSSDSEQLTNGLLMIFNQFFIGISTIFLTIFTMARLDLTMM
                     LVVVALTPVSLLVARYIAKKSYGYYRQQTQARGRQSQLLEESISQLTLVQSFNAQEQF
                     TQGFQVVNDQYATYSQQAIFASSTVNPSTRFVNAIIYALLAGLGALRIMAGNFTVGSL
                     TTFLNYASQYSKPFNDISSVLSELQSALACADRLFAILALDSIDDQAERKIDSEELKG
                     AISFDNVSFSYSPERSLIEHLDIAVKAGQKVAIVGPTGAGKSTMINLLMRFYDVTAGQ
                     IVLDGVPISQYSREDLRRQIGMVLQETWIKSGTIHDNIAYGYPNATRELVIEAAKAAN
                     ADFFIRQLPQGYDTVLADGGEGLSQGQRQLLSIARVFVKIPKILILDEATSSIDTRTE
                     ILVQEAFAKLMEGRTSFIIAHRLSTIQSADLILVMVDGKIVEQGNHEALMAEQGVYYQ
                     MQTSQQTEEDESVR"
     gene            26450..26842
                     /locus_tag="AC1PIV_000493"
     CDS             26450..26842
                     /locus_tag="AC1PIV_000493"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0047617 - fatty acyl-CoA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HIP6611542.1"
                     /translation="MKVLDKLNLQPITVLDDYQATMLNEKEVLMTTKVTEKSLNPYGM
                     AHGGFLFTLADSVAGLTTVASGSYSVTLQSNIHYMKAAKLGDTLSVIGSCTHDGSRTK
                     VVEVKIENQDKQLLASASFTMFVTGKVE"
     gene            27020..28180
                     /gene="mutY"
                     /locus_tag="AC1PIV_000494"
     CDS             27020..28180
                     /gene="mutY"
                     /locus_tag="AC1PIV_000494"
                     /EC_number="3.2.2.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HIP6611543.1"
                     /translation="MLNLKEYGIEMWPEEKIQAFRKALLDWYDANKRDLPWRRTKDPY
                     AIWVSEIMLQQTRVDTVIPYYERFLHHLPTISDLAQAPEEVILKLWEGLGYYSRVRNM
                     QKAAQQMVEDFDGQFPTTHAAISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLSR
                     LFEVDYDIGLPANRKIFQAMMELLIDSERPGDFNQALMDLGSDIESPVNPRPQDSPVK
                     AFSAAYLNGTMDKYPIKAPKKKPIPVAYQGFLIRNKDNQFLLEKNNEAGLLSGFWSFP
                     LLEKGAIVDKQVSLFEVAEEVVQPDIRQSFTELYGLTVDWQEQEFGIVQHIFSHRKWQ
                     IEMVEGVAETLNLPESKELKWVSVEDFPTYPFAKPQQKMWENFIKEKEKQKS"
     gene            complement(28843..29643)
                     /locus_tag="AC1PIV_000495"
     CDS             complement(28843..29643)
                     /locus_tag="AC1PIV_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIP6611544.1"
                     /translation="MILGDILKEYRSKNKLSMDKFAELSGLTKGYISMLEKNQHPKTK
                     KALLPTMDTLEKVAKGMAISVGELIEQLDSNQDIALTITPSQFKLFQQPIHPEVLTLD
                     NELKGDFHAQWLTFGQEQLAAMQTASVTPSASILHLDDYRERIELPVPGKVSAGTGYW
                     QDTDMNNLVSFYNDEIPDNQSYDTIAQVVGDSMAPHIEDGDYLFIRLTPHIPLNTIGI
                     FSVNGENFVKKFKGDYLQSLNSDYDDIYFSPEDDIRPIGQVVDIYSPD"
     gene            29774..30118
                     /locus_tag="AC1PIV_000496"
     CDS             29774..30118
                     /locus_tag="AC1PIV_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014917248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611545.1"
                     /translation="MKRITEISWNDIYKEWETYANHFGLATPINTEKLRNQKSKDFGK
                     GSLITLDLLADYDTDFEKTAAIWVALFCRDLIQDYAYLLNGRAYLTVNQIYFQALKQF
                     QSEAVIWSKPLT"
     gene            30264..30806
                     /locus_tag="AC1PIV_000497"
     CDS             30264..30806
                     /locus_tag="AC1PIV_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611546.1"
                     /translation="MFNLLNKKAEVSKVAEYWNDTLIERGILSANELLEGKCWRCKSS
                     HGVNMCQIVSSKWSKDTSLANQMVLCLSCQHEKPNVADTEIVWQWLEVENNERYWTLQ
                     GMAEYEKMYKKSVLQELWDMGIRDGEEVDTLVNKVTSLSRKNDIVLNRATLAGLFRCE
                     IEQMRRKAFLNWTGIFKLVS"
     gene            complement(31033..32079)
                     /locus_tag="AC1PIV_000498"
                     /pseudo
     CDS             complement(31033..32079)
                     /locus_tag="AC1PIV_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647375.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(32170..32358)
                     /locus_tag="AC1PIV_000499"
     CDS             complement(32170..32358)
                     /locus_tag="AC1PIV_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIP6611547.1"
                     /translation="MLPQNNSPLLLNRQQVAELLGIDPKSFGKYIRSHPDFQCFMVGK
                     QERYLKSKLVKFIESHCD"
     gene            complement(32447..33202)
                     /locus_tag="AC1PIV_000500"
     CDS             complement(32447..33202)
                     /locus_tag="AC1PIV_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009909915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611548.1"
                     /translation="MALGNVEKDTEGWIELINQYLQYCIEIGLSPYTQATYKVALAKV
                     LGVSSTNFIATQPRTRANRMNNRVLHKDYRLSNKNNDYWHKVVTSTGLRKSELIHVTG
                     DALQRGRDGRWYLNLAGHKHHTKGRRDRWSPIMATSQEEEEWLVAIFQRAGKKKVFHV
                     PKDLILDDFDGKKVPTALKSHKYPAEYAERVYRSVAREISKIRNRKEIIHLRKELVGI
                     SLDRKACKIVTKALGHNRPEEFPHSYAYILLKR"
     gene            33481..34248
                     /locus_tag="AC1PIV_000501"
     CDS             33481..34248
                     /locus_tag="AC1PIV_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HIP6611549.1"
                     /translation="MNKRERLEEITRLVNKKGTVRISEIVELLNVTDMTVRRDFIELE
                     EQGVLTKIHGGARSNKAFQYREYSHSEKHIQNKEAKQEIAERAAQLIEDGDTVFLGPG
                     TTVAFLAEAIKNLRLTVITNCMPVFTILSQKKTEDFQVFLLGGEYRQVTESFVGEITN
                     TSLEKMRFSKIFFSGNGLKGTDVMTSTLAEAYTQNIAIKHSLEKYLLLDATKIGKDDF
                     TSFCDLNDATALVTDMNAKDENYQLLSNHIEIISTKS"
BASE COUNT        10131 a         5965 c         7570 g        10587 t
ORIGIN      
        1 tagataaatt ttatcaatct catggttttc ggccttatga agaataatat cagcacggtt
       61 tctggttggt tcaatgaatt tttctaagtt agctagatta atgtttttcc aagtattctg
      121 ggcaatagat agaatttcag ggtacgtcat ctgggtaaaa cgatggtaat agttgttagg
      181 gtcatttttt gccaatgtca ataatttttg gaatcgctcc aagtaccagg tttcaatatg
      241 ctccacatca gcgtcaacgt atatagacag gtcaaaatag tcactgacat agaggcgctg
      301 gttttgtgga ttttgaaata cattgattcc ttcaacaatc aagaaatctg gagacttaat
      361 ttcctgagtt ttgttgggga taatatcata gatttcatgt gaatagacag ggatttggca
      421 gtcgtagccg ttttttatct tatcaaggaa atcaatcaat ttctccatgt cataggactc
      481 aggaaacccc tttttattta acagttgccg ttcttctaaa accgcatttg gctggagaaa
      541 accatctgtt gttactaatt caaccttggc gtatttaaat gtccgagcga taagaatttg
      601 cagcaatcta ctagttgttg atttgccgac agcaacactt ccagaaacgc caatgataaa
      661 tggttgtggc ttgatagtct tctgtagaaa taaactcttc gtaaaattta ggtctttgcg
      721 tgctttccga tagatatgga taagattaac caaaggaaga tagatgtcag aaacctcatg
      781 taattggatg cggtcgttaa aacttttaat agaatttagt tcgctttgac taagtggaat
      841 ggtagtctta cgatgtagtt gttgccaagt ggctcggtca atttgttcaa aatttaaaaa
      901 ttcatttttc atacataatt cttcctatag gtaagcgttt caatatcgat ttcattttat
      961 catatttttc atgtaagaaa aactcttgaa aacgttttta ggaaatgtta taataagtac
     1021 atgtccaata tgtattacga aaaaaatcct acaatagcac atgatattca tgaaatccac
     1081 gtaaacttac tagacacccc aatgtctttc atgacagatg caggtgtttt tagcaagaag
     1141 atggttgatt atggtagtca agtgctttta aaaaaccttt attttgaaaa aggggcatca
     1201 gtgttggatg ttggctgtgg ttatggacca attggtttga cacttgctaa ggtgtttagt
     1261 accaagacaa cactgattga tattaatagc agagctttgg atttagctac aaaaaatgca
     1321 gagaggaatg gtgttatcgc taaaatttat caatcaaata tctacgagaa tgtggacgaa
     1381 acatttaatc atattgtttc aaatccacct attcgggccg gaaaatcggt tgtacatgaa
     1441 gtaattgctg gggcttttca acgcttaaag gcacacggaa ccttgtccat tgtcattcaa
     1501 aagaaacaag gcgcaccgag tgctaaagct aagatggaag aggtgttcgg caactgccag
     1561 attataaaga aagataaggg ttactacatc cttgaaagtg tgaaagaatg agagcagttg
     1621 atttaattca aaaaaagcgt gatggcttag aactatcgtc tgaagaaatc aaatggttga
     1681 ttgatggata tgtagctggg acagtaccgg attatcaaat gtcagcctta gcgatggcga
     1741 tttattttaa agggatgtca acgcgtgaga tttctgattt gacgatgtcc atggttgcaa
     1801 cgggtgaaca gattgatttg tctgcaattc caggcatcaa ggtagataag cattctacag
     1861 gtggtgtcgg agataaggtc acactcatct tagcgccatt ggtagcaagt tttgatattc
     1921 cagttgcaaa gatgagcggt cgtgggcttg gtcatactgg tggaaccttg gataagttag
     1981 agtcaatcaa aggataccag attgaagtta gtcaagcaga tttcatcaag caagttcaag
     2041 atactggtgt tgcagttatt ggtcagtcag ataatcttgt caaagctgat aaactactct
     2101 atgcccttcg tgacgtgaca gcaaccgttg acattattcc gctgattgcc agctcagtaa
     2161 tgtctaagaa aattgccgca ggtgcggatg cgattcttct agatgtcacg gtgggagaag
     2221 gtgccttcat gaagactgtt gaagaagcac gggttctagc tcaaactatg gtggatcttg
     2281 ggaaagcggt tggtcgtaag acagttgctg ttttaactga catgtctcaa ccagttggaa
     2341 cttcgattgg aaatcgtttg gaaattttag aggctattga aattttacag ggtaaaggtc
     2401 gagaagatgt taccgaattt atctgtgaat tagcccaaat tatgttgggg cttgctaatg
     2461 ttgagaaaag cattgaagaa gtacgtcaac atattgacaa tggtgcagca ttgaagaaat
     2521 ttgaagagat ggtccgtgct caaggtggtg acttagaaga tttatatcgc ccagttcagg
     2581 ttacacagca agttccagtt cttgcggaag aggatggcta tattgtggga cttcctgctt
     2641 tggaatttgg tctctttgca atgaaacttg gtgcaggtcg tgcagtcaaa actgacaatt
     2701 tagattatga aacgggtatt gttttccata agaaagtggg ggaagctgtt tctaaaggcg
     2761 aacaaatcgc aacgatttat gccaatgaaa atatttcgga aaacatgctt acaaatttcc
     2821 aaaaaaatgt taaaatagat aaagaaagtg taaaaacaaa agaaatcatc gagattattt
     2881 cttaatgtac ggagaaagct atgaaattga ataaatatat tgaccataca atcttgaaac
     2941 ctgagacaac acaagagcag gttgaaaaaa ttttagcaga agcaaaagaa tatgattttg
     3001 caagtgtctg tgttaaccca acttgggttg ctttagcagc tgaaagcttg aaagatagtg
     3061 atgtaaaagt ttgtacggtt attggtttcc ctctcggagc aaacacacct gctgtaaaag
     3121 cgttcgaaac aaaagatgca atttcaaatg gagcagatga gattgacgtg gttatcaata
     3181 tcggtgctct gaaaactgga aattacgatt tggttttgga ggatattaaa gctgttgtag
     3241 cagcaagtgg tgataaacta gtcaaagtta tcatcgaagc atgcctcctt actgatgatg
     3301 agaaagtgaa agcttgtcaa ttatctcaag aagctggtgc ggactatgtt aaaacatcta
     3361 caggattttc tacaggcggt gctacagtag cggatgttgc cttaatgaga aaaacagtgg
     3421 gtcctgacat gggagtgaag gcttcaggtg gtgcacgttc gtatgaagat gccattgcct
     3481 ttatcgaagc aggagcgtct cgtattggtg cgtcatcagg cgtggcaatc atgaatggag
     3541 cacaggcgga tggagactat tgatttaatt gaattagctg taaaaaacag tcaaaaagca
     3601 tacgtaccgt actcaaaatt tccagttagt gcagttcttg tagctaagac aggggaaata
     3661 tttacgggtg taaacattga aaatgcaagc tttggtttga ccaattgcgc tgaaaggaca
     3721 gctattttca aggccatttc tgaaggtgtg aaagattttt ctgaaatcat tatttatggt
     3781 aaaacagaaa aaccaatatc tccttgtgga gcttgtcgcc aagttatggc agaatttttt
     3841 gataaggatt taaaagtgac cttggtcgct aaagataaat cgacagtcga gacgacagtc
     3901 ggggaattac taccatattc ctttacagac ttaacgtagt ctgtatgaca gtcatttgac
     3961 tgtagcaata ttactctgca acaatgtagt tgcaaaaaga tttttaggag ggttcagaaa
     4021 tgaacaagaa acttgttgga ctgggtctag cagctgctgc ggctgtatct ttggctgcat
     4081 gtggtaaccg tgcttcaaaa agcagtagct cagaagcatc ttcatcagcg gacacatctg
     4141 tgaaagctgc tatcgttact gacattggtg gtgttgatga ccgttcattt aaccaatctg
     4201 cttgggaagg tcttcaagag tggggtaaag cagctagtct ttccaaaggt aatggctacg
     4261 attacttcca atcagctagt gaatcagatt atatcacaaa ccttgattca gctgttgctg
     4321 gtggttacaa tcttgtgttc ggtattggtt ttgccttgga gagtgcgatt gctgaggttg
     4381 caccaaataa tcctaataca cactatgtaa tcgtggatag tgttgttcca gatcaagaca
     4441 atgtagttag cgtaggtttc gcagaccatg aagcatcata tcttgctggt gttgctgcag
     4501 ctaaatcaac taaaacaaat cacgtaggtt tcattggtgg tatggaaggt gttatcatcg
     4561 atcgctttga agctggtttc gttgctggtg ctaagtctgt aaacaaagac atcaagatta
     4621 cagttgacta tgcgggttca tttggtgatg ctgctaaagg tcaaactctt gcagctgctc
     4681 aatatgctgc aggtgcagat gttattttcc acgcttctgg tggtactggt aacggtgtat
     4741 ttgcagctgc taaagcagaa aacgaaactc gtaatgaagc agataaagtt tgggtaatcg
     4801 gtgttgaccg tgaccaatca gcagaaggta catacacttc taaagatggt aaatcttcta
     4861 actttgtatt ggcttcaaca ttgaaacaag ttggtacttc ggttaaagat attgcaacta
     4921 aggcagctgc aggtgatttc cctggcggtc aagtacttca attctcattg aaagataaag
     4981 gtgttgaatt ggcagaaact aatctttcag aagatgcttc taaagcagtt gcagatgcta
     5041 aacaagcaat tttggatggc aaagtagaag ttcctgaaaa accttaatga atttcttttc
     5101 gacaattccg attcggcgac ccgacggggc gccgttttcg ggctgagatt tttgtcagta
     5161 aagcctatca gctatggtag gttttactga caaaaatggt atagttgatg aagagttttt
     5221 aagtactcaa agtagtactg aagaattttc agaaggctat agtcagaaag gataatagat
     5281 tatgactaag gattatgtca ttgaaatgcg caatatcact aagatatttg gtgaatttgt
     5341 agcaaatgac cacatcaatt tgaatgtcag acgtggtgaa atccatgccc ttcttggtga
     5401 gaatggtgcg ggtaaatcta ctctgatgaa catgcttgct ggcttgttgg aacctacaag
     5461 cggtgaaatt gttatcaacg gtcaatccgt gaagattgac tctccatcca aagcagccca
     5521 attgggtatt ggtatggtgc accaacactt tatgttggtt gatgctttca cagttgcaga
     5581 gaacatcatt cttggttctg aaaccaccaa aggtggcgtg attgacctta aaaaagccat
     5641 cgcagaaatt aaagaacttt ctgctaaata tggtcttgaa gttgatccaa ctgcaaaggt
     5701 tgcagatatt tctgtgggtg cacagcaacg tgtagaaatc cttaaaacac tttaccgtgg
     5761 agcagacctt ttaatttttg atgagccgac agctgtattg acccctgcgg aaattgcaga
     5821 gctcttgaaa attatgaaag ccttggttga agaaggtaaa tctattattt tgattacgca
     5881 caaactggat gaaattcgtg cagttgccga tagtgtaaca gttattcgtc gaggtaaatc
     5941 aatcgaaaca gttgccgttg aaggagcaac aaaccaagat ttggctgagt ggatggttgg
     6001 acgttccgtt tcctttaaaa cagagaaagt tgaagcgagt cctaaagaag tcattttgtc
     6061 aattaaggat ttggttgtca atgaaaaccg tggtattcca gcagttaagg gcttatcgct
     6121 tgatgttcga gcaggtgagg ttgttggtat tgccggtatc gacggaaacg gtcaaagtga
     6181 gttgattcag gcaatcactg gtttacgtaa ggtaaaatct ggctcaatca ctatcaaagg
     6241 tgaggaagta gttggtaaaa ctccacgtaa aattacagaa atgcaagtga gccacgttcc
     6301 cgaagatcgt catcgtgatg gactcgttct tccgatgact gttgctgaga actttgcgct
     6361 tcaaacttac tataaagaac cgatttcaaa aaatggtatc ttgaactata atatcattaa
     6421 tgaaaaagca cgcgcgttaa tggaagaatt tgacgttcgt ggggcaagtg aactcgtccc
     6481 aatcaaggct ctttcaggcg gtaaccagca aaaagctatc atcgcgcgtg aaatcgatcg
     6541 caacccagac cttttcattg ttagccaacc aacacgcggt ttggacgttg gtgctattga
     6601 gtatattcgt aagcgtctta ttgcagaacg tgataagggt aaagctgttc ttgttgtcag
     6661 cttcgaattg gatgaaattt tggatgtatc agatagaatt gctgttatcc atgatggtgt
     6721 catccatggt attgttgaac ctgctaagac caataaacaa gagttaggtg tcttgatggc
     6781 aggtggacat attgagaagg gagaagaaca tgcttaataa atataagaat ttggcccttc
     6841 cattaatggc tgtggtcagc ggtatcctac ttggagcgat tgtcatgctt gtttttggct
     6901 acgatccaat ttggggctat gaagagttat tctattcagc ttttggtaat atcaaatcaa
     6961 ttggtgaaat tttccgtgca atggcaccac ttgttttcac tgctctcggt ttcgcagtag
     7021 ctagtcgtgc aggtttcttc aacgttggtt tgtctggtca ggcctatgtt ggttgggttt
     7081 ttgctggatg gtttgccttg gcaaatcctg acttaccacg tccagttttg attttgggaa
     7141 cagtcttaat tgccatgttg gcaggcggta ttgctggagc tattccaggt attctacgtg
     7201 cctatttggg aacaagtgaa gttatcgtta cgattatgat gaactacatc ttactctatt
     7261 catgtaacta tatcattcgt gatgtatttg cagatagttt gatgaaaaat acagactcga
     7321 cagttaacgt gtcagcaaat gcctcttacc aaacagagtg gctccgtgca ttgacagata
     7381 actcacgtat gaatattggt attttctttg ccattattgc agtttttgtg atttggttcc
     7441 tattgaccaa aacgactctt ggttttgaga ttcgctcagt ggggcttaac ccaacagcat
     7501 cggattatgc gggtatgtct gcgaaacgta cgattattct atctatgatt atttcaggtg
     7561 ctcttgcggg tcttggagga gctatccaag gtttgggtac tttccaaaac gtttatatcc
     7621 aaagtggtaa cttggatatt ggttttaatg gtatgtcagt agcgctttta gcttctaatt
     7681 caccgttagg tattccattg gctgcctttc tattcggtgt tctttctgtc ggtgctccag
     7741 gtatggtacg tgcacagatt ccacctgaat tgatcaacgt ggttacggca tcaatcattt
     7801 tctttatcgg tgtgaaattt atttttgaac aattattaaa atctagaaat aaagcgaaag
     7861 gagcgaaata agatgaatgt ttcaattctt gccttactca tttcgcaaat gttgatttat
     7921 tcagcgccct taatctttac cagtcttgga ggagttttct ctgaacgcgg tggtattgta
     7981 aacgttggtc tagaaggaat catggttatc ggtgcctttg ctggtgttgt tttcaatatc
     8041 gaatttgcag ggacatttgg taatgctact ccattattag ctgttattgt aggaggtctt
     8101 gctggtgttg tctttgctgc tattcatgcg atggcgacga ttaatttccg tgcagaccac
     8161 gttgtatcag gtacggtgtt gaaccttttg gctccagcat tgggagtttt cctagtcaag
     8221 gttatctata ataagggtca aactgatagt attactgaat catttggtaa attttcattc
     8281 cctatcttgg cagatattcc aatcattggt gaaattttct tcaaaaatac aagcttgatg
     8341 ggttatgtag ctattgcaac agcatttctt gcttggttca tcctttataa aaccaagttc
     8401 ggtttgcgcc ttcgttcagt aggtgaacat ccgcaggcag cggatacttt gggaatcaat
     8461 gtctacgcta tgcgttatgc aggtgtgttg attgctggtt tccttggtgg tgttggtgga
     8521 gctgtaagtg ctcaatcagt gaatatcaac ttctctgcaa caacaatcgt aggttcaggt
     8581 ttcatcgctc tagcagctgt aattttcggt aagtggaatc caattggcgc tatgcttgcc
     8641 agtctattct tcggtctttc gcaaagtttg gcagtagtgg gtggacaatt accaggattg
     8701 aaagatattc caacggttta tcttcaaatt gcaccgtatt tgattactgt tattgctctg
     8761 tctgctttct ttggtaaagc agtcgctcct aaaacagacg gtatcaacta tatcaaatct
     8821 aaataaaaag gtccagtgga cctttttatc atgttctttg ctgtacagga aatgaataat
     8881 tgtcctattc aaaggaagag gagctagagg gacttttagt tgagaatagg gagaatgact
     8941 ggtataatag tttgtcacta aggtatgaaa tgagattaat tgtgagacga ttggtgttaa
     9001 atattgcaat gagtttagat ggatttattg cacgtaagga tggaagctac gattggattg
     9061 aagggcatgg taccgataaa tacgatactg tcttacagtt tgataatcaa aaattcttta
     9121 acaactgtga tacagttgtg atggggagaa aatcattaga agattgtccg ttggaaatga
     9181 ttgaaggata tcaggaaaag caatttatcg ttgcgagtca taccgagcag acggactatg
     9241 gtaatgtgcg tttcgtaagg gacatcatcg ggtagattat ggaacttcgt tctagagaag
     9301 gtggagatat ttggttgttt ggtggagcaa gtctggttca ggactgttta gaggcgggag
     9361 tgattgatca ccttattatt gggattattc ctactatttt gggtgacggt attccacttt
     9421 tcgcctcact tttggaagaa aagaaattgc tcttggtaga gtcaactgtc acagatggaa
     9481 ttgctatgtt acgctatgat attagaaggt aaaaaaggcg agctattgct cacctttttt
     9541 actattttat ataattagtt ttttacacca gctgcaattt ctgggtttgc gaaagcatca
     9601 tcgatgatgt ctttcaattg tttagcagat gcttgcattt tttgcaattc agcgtcactc
     9661 aatgggatat tgactggacg aacgataccg tgtgcgccga tgatagcagg ttgaccgatg
     9721 aagacatctt caacaccttc atattgacca gcttggtaaa ctgacaatgg aagtactgca
     9781 ttttcatcat caaagattgc tttagtgata cgtgcaagtg caacaccgat accgtagtaa
     9841 gttgcgcctt ttttgttgat gattgagtaa gctgcatcac gaacagatac aaacaagtca
     9901 acaagacctt gctcatcaat atcgcggttg tcttgcaacc agtcgtacaa tttcacaccg
     9961 gcaacgttgg catgtgacca aactgcaaat tctgagtcac cgtgctcacc catgatgtaa
    10021 gcgtgaactg aacgtgcatc gataccgatt ttctcggcca atgcttgacg gaaacgagct
    10081 gagtcaagag aagtaccaga accgataaca cgctctttag ggaatccaga gaatttccaa
    10141 gttgagtaag tcaatacgtc aacagggtta gcagcaacaa ggaagatacc gttgaaacca
    10201 gagttaacga tttctgtaac gatttgttgg ttgatacgaa ggtttttctc taccaattca
    10261 aggcgagttt cacctggttt ttgtggcaaa ccagctgtca atacaaccaa gtctgcgtca
    10321 tgagcatctg aatactcagc agagtagatt tttttaggga atgtgaaggc caatgcgtgg
    10381 ctcaagtctt ctgcatcacc ttgagtacgg tctttgttga tatcgatgat acccaattct
    10441 tgaccaatcc cttggttaac aagagcataa gcataagcag aacctacggc accgtcaccg
    10501 acaaggatta cttttttgtg ttgtttagtt gcagtcattg ctaaacatct ccttagtttt
    10561 atttggggat gacttcatcc caaccataat acattctagc atgttttaag ctttttgtca
    10621 cttgtgaaag cgcctttgaa aatgtttaca tgctagtttc caacaaagaa atttattcgc
    10681 caatatggta taatagaagc acaatgactg ttgaaagagg catataatgc aagataaaaa
    10741 tttagtaacg gttaatctga ccaatgagat gaaatcatcc ttcatcgact atgcgatgag
    10801 tgttatcgtt tcacgtgctc tgcctgatgt acgtgatggt ctgaagccgg ttcatcgccg
    10861 tattttgtat gggatgaatg aattagggat tacaccggat aaaccacata aaaaatcagc
    10921 ccgtatcaca ggggatgtta tgggtaaata tcacccgcat ggagatagtg cgatttacga
    10981 agcaatggtt cgtatggcac aatggtggag ctaccgtcac atgttagttg atggtcacgg
    11041 aaactttggt tccatggatg gcgatggagc agccgctcag cgttatacag aagcacgtat
    11101 gagcaagatt gcgcttgaaa tgcttcgtga tattaacaag aacacggtaa attttgcgga
    11161 taactatgac gcgagtgaac gtgagcctga ggttttacct gctcgtttcc ctaaccttct
    11221 ggttaacgga acgactggta tcgccgttgg tatggctacc aacattcctc cacacaactt
    11281 gggtgagact atcgaggcag ttaagctggt tatggacaat cccgaggtaa caacacgtga
    11341 gattatggaa gtcttgcctg gaccagattt tccgacaggt gccttggtta tggggaaatc
    11401 tggaattcac cgtgcttatg aaactggtaa aggttcaata gttcttcgtt cccgcacaga
    11461 aattgaagaa tatggaaatg gtcgtgaacg cattgttgtt acagagtttc catacatggt
    11521 caataagtcc aaggttcaag aacatattgt caaattagtc caagaaaaac gtattgaagg
    11581 aatcactgct gttcgagacg aatccaaccg tgagggtgta cgatttgtta tcgaagttcg
    11641 tcgtgatgct tctgctaacg ttattttgaa taacctattc aagcaaacac agcttcaaac
    11701 caactttagt ttcaacatgt tggccatcca aaatggtgta ccgaaaattc tttctgtacg
    11761 tcagattcta gagtcttata ttgaacacca aaaagaagta gtcactcgtc gtacacgatt
    11821 tgataaagaa aaggctgagg cgcgtgctca tatcttagaa ggcttgctga ttgctcttga
    11881 ccatattgat gaagtcattc gtattatccg taattcagaa actgatgcta ttgctcaagc
    11941 tgaattgatg gagaaatttg acctttctga acgtcagagt caggctattc ttgatatgcg
    12001 tcttcgtcgt ttgacaggtt tggaacgcga caagattcaa tcagaatatg atgagttagt
    12061 ggccttgatt gcagatttgg ctgacattct agctaagcct gagcgtgttg ttcagattat
    12121 taaagacgaa ttagaagaag tcaaacgtaa atatgctgac ccacgccgta cagaattgat
    12181 ggttggtgaa gttctatccc ttgaagatga ggacttgatt gaagaaacgg atgttttaat
    12241 caccttgtca aaccaaggct acatcaagcg tttggcacag gatgagtttc aagctcagaa
    12301 gcgtggagga cgtggggttc aaggaactgg cgtcaaggat gatgattttg tacgagaatt
    12361 agtctctaca agcactcatg atcgcttgct cttcttcact aataagggac gtgtttaccg
    12421 tctcaaaggc tatgaaatcc cagaatatgg tcgtactgca aagggacttc cagtggtcaa
    12481 tttgcttaaa ttggaagaaa acgaggcaat tcaaaccatt atcaatgtaa ctaaggacca
    12541 ggaggcagat agctatctct tctttgcaac ccgccaaggt gttgtaaaac ggactagtgt
    12601 gtcagaattt gccaatattc gccagagcgg tctgaaagct ttgaatttga aagaagacga
    12661 tgaactcatc aatgttttct taacaaatgg ccaagcagac attattatgg ggactaagtt
    12721 cggttattct gtacgtttca ctgaaacaga tgttcgtaat atgggccgta cagcaacagg
    12781 tgttcgtggt atcaatttac gtgagggaga ccagttagtt ggcgctacta tgatttctga
    12841 tgaccaagaa gtactcgtat tgacggaaaa aggttttggt aaacgtacac cagccagtga
    12901 gtatccaacc aaaggtcgtg gtggtaaggg tatcaagact cttaaagttg ctgataagaa
    12961 tggttctctg gcaggtttga caacggtatc tggtgatgaa gatattatgg ttattaccga
    13021 tactggtgtg attattcgta caagtgttgc caatatctct caaactggtc gttcaaccat
    13081 gggggtaaaa gtgatgcgct tgaatggtga agcgaaaatc atgacctttg ccttggtaga
    13141 tgctgccgaa attaaagaag aaaaggaata aatagtcatg tcaaaacgtg aaaacaagaa
    13201 gaagcgtaaa ggttcttttt ggcgcaatct tttaacagtt gtattgatac tgatttcctt
    13261 ggcattgata ttcaacacct ctatccgtaa ttttattatc ggctggaata cgaataaata
    13321 ccagattagc aatgttacga cagaggatat cgaaaagaat aaacaggctg agacaacatt
    13381 tgatttcgaa caggttcagt ctatttctac agaagctatt ttagcagctc agtgggatgc
    13441 acaacgctta cctgtaattg gtgggattgc ggttcccgag cttggtatca accttcctat
    13501 ttttaaaggg gtcttcaata cttcgctcat gtatggagct ggtaccatga aggaaaacca
    13561 agagatgggg aaaggaaatt atgcgttggc cagccaccat atttttggtg taactggtgc
    13621 ggcagatgtt ctcttttcac cgcttgatcg tgctaaaaac ggcatgaaaa tctatattac
    13681 tgacaagacc aatgtttaca cctacgttat tgatagtgtg gaaattgttt cgcctgaaag
    13741 tgtctatgtc attgatgatg tagaaggacg tacagaagtt acgttagtga catgtacgga
    13801 ctattatgct acgcaacgta ttgttgtaaa aggagttctt gaatcaacca ctccatataa
    13861 tgaaacggca aaagacatct tagattcctt caataagagt tataatcagt atgattatgg
    13921 acaataaaac atctatatat taaggataaa gaagtggtat aggactgagg agataatctt
    13981 tggttttata tggcttcttt tttgcaagat tttacgaata gataggtgag gaggaaatta
    14041 tgtatcaaat tgaatttaaa gaagaggcct ttctacctag agaacgttta gtagaagttg
    14101 gagctgagcg tctcagtaat caggaactac tagcaatttt tattagaact gggacaaaaa
    14161 aagaacctgt ttctattctc tccaataaat tattgaatcg tttggagagt ttagcggctc
    14221 taagagaact atcaattgaa gaattgcaaa gtttgactgg aattgggcgc gtcaaggcga
    14281 ttgaaattaa ggctatgatt gaacttggaa aacgtatcaa tcaatcagag ctactcttaa
    14341 atgagagaat tttgggaagt gagaagttgg gacgtaagat gattcatgaa atcgggcata
    14401 agaagcagga gcatctagtt gcactttatc tcaatacaca gaaccagatt atcagtcaaa
    14461 aaacgatttt tattgggagt gttaatcgta gcattgcaga accacgtgaa attttgcatt
    14521 acgcagtaaa atgtatggca acatcgatta tcatcgttca taaccacccg tcgggttcag
    14581 tacaacctag taggaatgat ttgctattta cggagaattt aaaagagtcc tgcgaaaagc
    14641 taggactggt attattagat catttaattg ttggaaataa ggattactat tcttttagag
    14701 aagaaagtga gttattttaa agtttattga caatatagtg gaagaggtct ttttcaatct
    14761 cacgtttacc gtagagtagt tcaggatgcc attgaacccc taaaaattta gttgggtagg
    14821 ctgaatgaac tgcttcaata atctgttgat tatctgatag tgcaatgatt tctaagtcag
    14881 gggctaagtc tttgatagcc tgacggtgaa atgagttcac actcggatcg gactcatata
    14941 tgtcgtaaag tggactattt tgagtcagtt gaatcgtttg actgacttct tgtccgtcta
    15001 tgtcttgcca atgttcagaa attgattgat gaaggctacc accttgagct acattgtaga
    15061 gctgtagacc tcggcagata ccgaagatag gtttctgatt ttcttgggca gcccttatga
    15121 gggctaattc aaactcgtca cgctttggta gataattatc gctgtcaata gtcctttctt
    15181 cgtgatagta acttggctgg acattttgtc ctcctgttag gatgagtttg tcaataagat
    15241 gaatataata ttttgccaaa tctggctctg tagctggaag gatgagtggg agcccaccag
    15301 catcttcaat agcttgtacg aggcaagtct gggtataaga aagcaggggt tctgtatgat
    15361 cccctgtttt atattcattt ccagaaatac caataactgg ttttttcatt gcttatcctt
    15421 ttcgcataaa gtagagtagt gtctgtaatt cactagtcaa atcaacatac tgaacaacga
    15481 catcttttgg gacagacaag ttaactggtg aaaagctcag aattcccttg acaccagctt
    15541 caacaagaat atcggtcact tcttgtgcct tgacgctggg taccgttaga atggcggtct
    15601 gagagtttgc ttcgctgata cgttccttga tttctgagat tgcatggatt gggatatttt
    15661 catctgtcgt tccaacagct ggattatcat ctgcttcaaa agccatgact attttcattt
    15721 tatttcgttc gtggaagcga tagtgtagta aggcccgccc catattccca acacctacaa
    15781 gcataacatt ggtgatggag gtatcattta gaatatccgc aaagaaatcc atcaactctt
    15841 tgacgttgta gccaaagcca cgacgaccaa gctctccaaa ataggaaaaa tctcggcgga
    15901 cggtagctga atcgattccg atagcttcgg caatttcttt tgaactagct ttttcaatat
    15961 ttcctgcata gaaacgttta aaaatgcgat agtagaggga tagacgtttg gcagtagcgc
    16021 gtggaatatc agatttttta tcgtttttca ctttagactc ctttatttcg atagaatacg
    16081 ctttatcgat tatttatata ttaaacagtt ctttattcta ttctagtcca agtttgtgaa
    16141 aaaatcaaca gattgatttt aaaaaaagat taaacaggaa actgtctaat ctagtgtttg
    16201 taaatagcga tagagatctc cgattgtccc tttgtaatcc agagcttgtc cgttttgtgt
    16261 aatgctggta actggataat agtctgggag ggttaagcaa ccggaaaaag ccagaatggc
    16321 tgcatcctta ttctcaaatg tttggatacg ttcttgcttg taagcgtcaa gatagtgaat
    16381 ttcaatcata ctaactctct tttgtaaaga tgtcacggtc aatcaagcta tccatgagga
    16441 aatagaattt ttcttgaata accttgttac tttctggctt aaaaatgttt accagatgaa
    16501 gaccagactt gtcggtaatg ttaattttaa aaccagttag gtcttgattg ataataattt
    16561 tcaagaggaa tccttggttt gaatttggaa tttcttccag aagacgtgta agctgatagt
    16621 gacctgcttt ggtttgttca aaggtgttat cacggagtgt atattttttg atagcagggc
    16681 taatgtgata agtaaaatta caatctttta aggtaactga ttgttggaat gccattttaa
    16741 cctccaagta ttttctttag ttcgatgata agagtatcta tctcttcttt tgtattgatt
    16801 tcagataggc tgatacgaat ggattctttc agacgatggg agtcttttcc atacatagct
    16861 tctaaaacat ggctattttg gacaacacct gccgtacatg cagaaccgct agaaacagca
    16921 atacctgcca aatctagttg cataaggagt tgttcattaa gtttaccaag aaaaccgata
    16981 ttaaggacat gagggagatg aggtccagcc tgattgagat aatagtctaa gccagacaat
    17041 ccctcgataa tatgttgtcg cagttcactg acatgttgat gatgcgtatc taaggactca
    17101 tattgttctg ttagggcagt cgccatagca gcaatagcag ggagattctc agtacctgct
    17161 cgatgttgct gttcctgctt tccgccgtgg atcaaggaat caaatttatg aactttacta
    17221 tacaggaatc ccatcccctt tggaccatgg aatttatggg cagaagccgc gagcaagtca
    17281 attccgtagt cagagggaga aattgcaatt tttccaattg cttggacagc atctacatga
    17341 aagacggcct gatgatcggc taggagctct ccaatttcct tgatgggaag tagctgaccg
    17401 gtctcattgt tagcaaacat gacgctgact aaaatagtat ctggccgaag ggcatccaga
    17461 atttgttgag cggtgattac ttgattgact ggttggatat aggttacctc gaacccaaac
    17521 cgatcctcta gatactgcat ggtatggagg acagcatggt gttcgatagc cgtagtaatc
    17581 aggtgttttc ctttggattg atgcgcaagt gcatagcctt gaatagctaa agtatcagct
    17641 tcggagcctc cagatgtgaa aataatttgt tcgggagagg cggagagaat ctgagcaatc
    17701 tcttgacgac tttgtctaag acattgattg gctttccgac cgctttgatg aatactggag
    17761 gggtttccat aattttcttg agccacttcc atcatccgtt ggagtgcagt aggagataga
    17821 gcagtggttg ctgcattatc taaataaatc aaagagttac tcctagtttt ctttttcagg
    17881 actagtaaat ttgaaaagtg ggctgagtgg ctgatgttct tggatgcggt ggatggcatc
    17941 tgcaatcaag tcactagctg ttaggaaggc gatattttta ggatgctgtt ctttgcttgc
    18001 aacagaatcg gtaactaata tttctttgat tggtgcttca tctaagagtt gggctgcagt
    18061 tcctgcaaag agaccatggc tggcaactgc ataaatttca gtagcaccac cttcttggac
    18121 aatttttgaa gcttgtgaga aagtgcgacc agtattgaga atatcgtcca ccaaaatagc
    18181 ttttttacct gcaacatcac cgataatata gccttcagaa cgctcagaat catcttgagc
    18241 gtagtcgata atcgcaatcg gtgcatttag aaattcagcg atattacgcg cgcgtttgat
    18301 accagaattt ttaggactca caatgacgac atcttctccg cagagtcctt tttccatgta
    18361 gtaggctgca aaaagtggtt ctgtaaggag attgtctact ggaatatcaa agaaaccttg
    18421 aatttgtgaa gcgtgcaaat caagagtcaa tacacggtcg acaccagctt taaccagcat
    18481 atttgcaact aatttagctg taattggttc gcgtggagaa gcggtacggt cttgacgagc
    18541 atagccgaaa taagggatga cagctgtaat agtgttggca ctagcacgtt tacaagcatc
    18601 gatcataatc aataattccc acaagtgatt atttaccgga tagcttgttg attggataat
    18661 gtagacgtct acgccacgta cagattcttc aatgttaatt tgaatctcac catcagaaaa
    18721 ctgacgagaa gacagctttc caagaggaat tccagcagaa tcagcaattt tttcagcaat
    18781 atcacggttg ctattgagtg agaataattt aatgttatgt tcaccgagtg gttgtaccat
    18841 tttaaagtaa ctccttttac acactgagct tttatgatga cataaaagta ttttttacga
    18901 tagatagttc tattctatca aaaaaatgaa aaattttcag tagtgaaact aaaaaatcaa
    18961 ccttagttgg ctgatttttt atagttattt catgtgggca gcagttcgtg cgaccttact
    19021 actagcatat ttgaattgaa ttgatttctt cttaaggaat tcatcaaaaa gaattttccc
    19081 tgcatctgca tcggtcactt cgacttctaa ttcgtaatct ttttgtccca cataatcatt
    19141 ttcatcgagg gccataaggc ctatagatgt ctgtttctca tagcgttttg tcgtgaggat
    19201 tccccagaca gcaagtttat caagtggaat ttcggttgca gaaataatgt cagaaatttg
    19261 tcctgctggt agttgaaaat tttccagtaa atcatgagca gtttggatgt ctagaacttg
    19321 gttatattct tgattgccga cttcttgtgg aatttttaag gttagttctg ctgagtcctc
    19381 aaatgtacga atacggagtg aaaagcggtg attcttcata tctaggtctg gggtatcaat
    19441 gtagtggttt gtttgaagaa ttgggctcac atctgaaaag tcagtaagca ggcgtttgta
    19501 ttcggatttg gtcagtaagg ttttatactc aatttcaagg tggtttttca tgcagtaaac
    19561 cctttcaatg tgttataata gattagtctt tgtgttattc taatacaatt taaaagtttt
    19621 gacaagaaag gggccgtatg gactttaact gggaagaatt tttagacccc tatattcaga
    19681 cagttggtga attgaaaatc aaactgcggg ggattcgcaa gcagtatcgc aaggctaatc
    19741 ggcattctcc aattgagttt gtcacaggac gggtaaaacc gattgaatcc attaaagaaa
    19801 aaatggctct gcgacatatt aaattggaaa atcttgctca agatatgcaa gatattgccg
    19861 gtcttcggat tatggttcaa tttgtggacg acattgaaga agtattagct attttgcgga
    19921 aacgcaagga tatgcaaatt gtgcatgaac gggattatat caataatatg aaagcctctg
    19981 gctaccgttc atatcatgtg gtgattgagt atcctgtgga tactataaat ggcaacgaga
    20041 cggttctggc agaaatccag attcgaaccc tttccatgaa tttctgggct acaattgaac
    20101 attctctgaa ttataaatat aagggaaatt ttccagaaga aatcaagaaa cgcttggaag
    20161 ttacagcaaa aattgcttat gaattagatg aggatatgcg aaaaatccgc aacgacattc
    20221 aagaagcgca ggccttattt gatcctgcct atcgcaaact gaatgacggt gtgggcaaca
    20281 gtgatgatac agatgaagaa tacaggtaga aaaaaaatcg ctctgctcgc tagtcgaaat
    20341 cctaagagtg aagcggtgtc caaagaatta tggacaaagt taaaagaagc aaattttatt
    20401 ttgactccta aaaatccaga tattgtcatt tctatcggtg gagatgggat gcttttatct
    20461 gcttttcaca aatatgaaaa gttgattgat cgtgtacgtt ttgtaggaat tcacacgggt
    20521 catttggggt tttatacaga ttatcgcgat tttgaagtgg acaagctgat tgaaaatctt
    20581 aagcttgata caggtgctag agtatcgtat ccgattttaa atgttaagat caagatgaca
    20641 gatggtcgca ttgtcgaggc gcgtgcctta aatgaggcga cagtaaaacg tctttctaag
    20701 accatggtcg cagatattat tattaacaat gtgcccttcg aacgctttag aggggatgga
    20761 atttcggttt caacgccgac aggctcaaca gcctataaca agtcattagg tggtgctgtt
    20821 ttacatccaa caatcgaggc attgcagatt gcagaagtgg caagtttgaa caatcgtgtt
    20881 taccgcacct tgggttcatc cgttgttgtc cctaaaaaag acaagattgt gattgaacca
    20941 aagcatagtg accgttactc gattgcggta gacaataaga cttttgtcta tgatagtatt
    21001 gaaagtatag agtatcagat agacaatagt aagattcatt ttgttgcaac accgagtcat
    21061 actagttttt ggaatcgggt taaggacgcc tttattggag aggtggagta atgcggtttg
    21121 aattcattgc tgaccagcat actaaaataa aaactttttt gaaaaaacat ggtgtttcaa
    21181 aagatttgtt ggccaaaatt aagtacacag gtggcaatat ttgggtcaac gatattgagc
    21241 aaaatgcaac ttacttgcta gatattggag atagggttac aattgacata cctgctgaag
    21301 aggatttgac tggtagttta aaaccgattt tctttccgtt ggatattgtc tatgaagatg
    21361 atcattttct ggcgataaat aagccggttg gctacgcctc cattccttct gctttgcatt
    21421 catccacaat cgcaaatttt gtaaaaggtt atcttattga gcagaattat gagaataagc
    21481 aggttcatat tgtgactcgt ctggataggg atacatcagg cgtcatgctg tttgccaagc
    21541 acggctatgc ccatgcacga ctcgataagc agttacaggc caagcttatt cataaacgtt
    21601 attatgcttt ggtgaagggg aatgggcagc tagaagagac aggggatatt attgccccta
    21661 tcggtcgtcc agaagacagc atcattaccc gttgtgtgac aaagaatgga aaatatgctc
    21721 atacttccta tcgtgttgtg caatcgtggg gagatattca tttagtagat attcaactac
    21781 atactgggcg gactcatcag attcgtgttc atttttctca cattggattt ccattgttag
    21841 gagatgatat gtatggtgga agtttggaat gtgggataga acgtcaagcc ttgcattgtc
    21901 ataatttggc cttcgacaat cctttttcag ccgaaaggat tgatttggaa gcaccgcttc
    21961 ctgaggattt tcaggctgtc atcaatcagt taataagtaa ataaatttaa ggagtttgtt
    22021 catgaaaatt tttgagcaat tagctacaaa gctagagggt aaaaaagtac gtatcgtatt
    22081 gccagaaggt gaagaaccac gtatcttgca ggcgacaaaa cgtttggtaa atgagtcgga
    22141 tgtagtaccc gtcttgcttg gaaacccaga tcgtattaag atttaccttg acattgaagg
    22201 gattacagaa ggttttgaaa ttattgaccc agctcattat gatagatatg atgagatggt
    22261 agctgctttg gtagagcgcc gtaaaggtaa ggtatcagaa gagcaggcac atgagttgtt
    22321 gaaagatgtg aactactttg gtgttatgtt ggtatatatg ggcgtagtag aaggtatggt
    22381 atctggtgcg attcattcaa ctgcttcaac agttcgtcca gctcttcaaa tcattaaaac
    22441 agagccaggt gtatcgaaaa catcaggtgc cttcttgatg gtaaaaggtg aagagcgtta
    22501 tatttttggt gactgtgcta tcaacattga tccagatgct caaaccttgg cagaaatcgc
    22561 tatcaactca gcacgtactg ctaaaatgtt tggtattgat ccaaaagttg caatgctcag
    22621 ctattcaaca aaaggatctg gctcaggtcc taaagttgat aaggtggttg aagcaactaa
    22681 aattgctcaa aaattgcgtc cggagttgga tttggacggt gaattgcaat ttgatgctgc
    22741 ctttgtccct gctacaggta aattaaaagc accaggttcg agtgttgctg gtcaagcgac
    22801 tgtatttatc ttcccaggta tctcagctgg gaatattggt tataaaattg ccgaacgtat
    22861 gggtggattt gcagcggtag gtcctgtttt acaaggtttg aatcagcctg taaacgactt
    22921 gtctcgtggt tgtaaccctg atgatgttta caacttgacc ttgattactg cggttcaggc
    22981 tttggagcac cgttaatatg aaatttttat cacgatattt taaggactat attaaggaat
    23041 ccatattagg tccagttttt aaactattgg aagcttgttt tgagcttttg gtaccattaa
    23101 ttatcgccta tatcgttgat acaattattc caaatggcag ccagggaaac ctggttgcta
    23161 tgcttttttt actggttggt atagcatgta ttggaattat tgtttcacta atagcgcaat
    23221 attattcagc taaagcagca gttggagtga ctaaagagct gacgaatgac ttgtatcaga
    23281 aggttctttc ccttcccaag tctagccgag atattctttc ctcatccagt ttgctgacac
    23341 gattgaccag cgacacttta caaattcaaa cgggtattaa tacttttctt cgtttgtttt
    23401 tacgtgctcc aattgtcgta tttggttcgc tcatcatggc attctatatt agcccaagtc
    23461 tatctgccta ttttctagga atgattatcc tattgatttt tatagtgaca gtcatttctg
    23521 ttatgaccag ccgtatttat caatcgatgc gaaaagaatt agatggtttg gtggggcagg
    23581 tacgtgagac cgtgactggt tggcgagtga ttcgtgcata tggacaaaga gagcgggaaa
    23641 ttaaggcttt tcaaggcata aatcagattt ataagaagca acagttgcag gctggttttt
    23701 ggtctagtct tttatcgcca ttgacatttt tggtggtcaa cagcacctta ctcattctca
    23761 tctggcaagg aaatatagcc atttcacaca atttgttgga acaggggatg ttggtcgctc
    23821 ttatcaacta ccttcttcaa attttagtcg aattggtcaa gatgattatg gtcgtgtcta
    23881 ctctcaacca gacctatatt tcagcgcaac gtattcaaga ggtgtttgac caaacatctg
    23941 aggatgtaga gtctagtttg ccaaaagtgg ttagtgagga taaggaaatc atcttttctg
    24001 tgcgtcatct ttccttttct tatccaaaat ctgctgagga gtccctgtct gacattactt
    24061 ttgacttacg taaggaacag tttatgggaa ttatcggggg aactgggtca ggtaagtcca
    24121 ccctagtaga tttattgcag gcactctatt cagtgccaac aaatcagctc tctctcttca
    24181 ttgatggaaa aagtcctaag aatttaaaag agtggcggca gcgaattgcc atcgttccgc
    24241 aacaggccca gctttttgct ggaactattc gttctaattt atctttagga ttggaagaaa
    24301 tatctgatag tgacctatgg tctgctttag aaattgcaca ggctaaatct ttcatagagg
    24361 ataaaggtgg tttggatagc cctgtcgaag cctttgggaa gaatttttct agtggacagc
    24421 gtcaacgttt gaccattgca cgcgctattt tacagaaagc accgatttta atcttagatg
    24481 atgcaacatc tgctctggat tatttgacgg agagtcgatt attagctgct attcgccagg
    24541 aattaccagg tcagaactta atcatggtgt cacaaagaac caatagttta cggacagctg
    24601 atcagatttt ggtcttggaa caagggcgtc aagttggact tggtcgccat gaggacttgc
    24661 tgagaagctc tgctatttat caagaaattc accaatcgca acaacaagga gaggaggata
    24721 gctatgagac aatctagttt taaggaactg gtcagattgg ttctacacca gccccttcga
    24781 atgtccttga tgttggtggg aactttggtg caagtccttc tgacagttta tctgcctatc
    24841 ttgattggtc aggcagttga tgcagtattg atagcaaatg gtcaggtctt gctcggtatc
    24901 ttaggcaaaa tggtgatggt tatcttgctt aatacactgg tgcaatggta cttacctttg
    24961 gtaaccaatc gcttggttta cggaatggtg gccgacttgc gtgaacaggt ctatgtgaag
    25021 ctgcaccaga tgcccttatc ttatcttgat cgtcaatcag tcggtgactt ggtggctcgt
    25081 ttttcaagtg atagcgagca attaacaaat ggtctcttga tgattttcaa tcaatttttc
    25141 attggtatct cgaccatttt cctaaccatt ttcactatgg ctaggcttga cttgacgatg
    25201 atgttggttg ttgttgccct gactccagtt tctctgcttg tggcacgcta tatcgctaag
    25261 aaatcctatg gttattatag gcaacagact caggcacgtg ggaggcaatc tcagcttttg
    25321 gaagagtcca tcagtcaatt gacactggtt caatctttca atgctcaaga gcaatttacg
    25381 caaggttttc aagttgtgaa tgaccagtat gcgacctatt cccaacaggc tatctttgcc
    25441 tcttcaacgg tcaatccaag tactcgcttt gtcaatgcta ttatttatgc cttacttgca
    25501 ggacttggag cgctaagaat tatggcagga aattttacag tgggatccct gacaaccttc
    25561 ctcaattatg ctagtcagta cagcaagcct tttaatgata tttcctcggt cctatcggaa
    25621 ttgcagagcg ccttagcttg tgcagacagg ctgtttgcta tcttggctct agatagcatt
    25681 gacgaccagg ctgagcggaa aattgattca gaggagttga agggagctat ttcctttgac
    25741 aatgtgtctt tctcatatag ccctgaacgt tctctgatag aacatttgga cattgctgtc
    25801 aaagctggac aaaaagtagc cattgttgga cctactggtg ctggcaaatc aaccatgatt
    25861 aaccttctta tgcgcttcta cgatgtgacg gctggtcaga ttgtcttaga tggggttccg
    25921 attagccagt atagtcgtga ggatcttcgc agacagattg ggatggtttt acaggagaca
    25981 tggatcaaat ctggtaccat tcatgataat attgcctatg gctatccaaa tgccacgcgg
    26041 gaattggtca ttgaggcggc taaggcagct aatgcagact tctttattcg tcagcttccg
    26101 cagggctacg atacagtttt ggcagatgga ggagaaggct tatcccaggg acaacgtcag
    26161 cttttgtcta ttgcgcgtgt ctttgtcaag atacctaaaa tcctgatttt agatgaggcg
    26221 acttcctcta ttgatacacg gacagaaatt ttagtacagg aagcatttgc caaattgatg
    26281 gaaggacgga ccagttttat tattgctcat cgcctatcaa ccattcaatc agctgacttg
    26341 attttggtca tggtggatgg aaaaattgtt gaacaaggga atcatgaagc gttgatggct
    26401 gaacaaggcg tttattatca aatgcaaaca agtcagcaga cagaggagga tgaaagtgtt
    26461 agataaatta aacttacaac cgattacggt tttagatgac tatcaagcta caatgctcaa
    26521 tgagaaagag gtgctaatga ccacaaaggt gacggaaaaa tctctcaatc catacggtat
    26581 ggcacatgga ggctttcttt tcacattggc agattcagtt gcaggtctga caacggtagc
    26641 aagtggttct tattctgtca ccctacagtc caatattcat tatatgaagg cagctaaact
    26701 tggtgatacc ttatcagtaa taggctcttg cacacatgat ggaagtagaa caaaggtcgt
    26761 cgaagttaag atagaaaacc aagataaaca gctacttgct tcagcaagtt ttaccatgtt
    26821 tgtaacagga aaagtagaat aaaactcttc gaacatcaaa agcagacagt cttggctaga
    26881 tttagaaaaa caaattcgtt cgctctattt ccaacctcca aaggttcccc aaacctttgg
    26941 agctagtttg attttgatta taaacgatat aagggagttg gcaaaagctg gctccctttc
    27001 tttgtgttat actagatgta tgttaaattt gaaagaatat ggaatcgaaa tgtggccgga
    27061 ggaaaagatt caagcttttc gcaaagcact cttagattgg tatgatgcca ataaacgtga
    27121 cttgccttgg agacggacca aggatccgta tgctatatgg gtttctgaaa tcatgcttca
    27181 acagacaaga gtagacacgg tcattcctta ttatgaacgt tttctccatc acttgcctac
    27241 gattagtgat ttagcacaag caccagagga ggtcattctc aaactctggg agggattggg
    27301 ctattattcg cgcgtgcgga atatgcaaaa ggcggctcag caaatggtag aagattttga
    27361 tgggcaattt ccgaccacgc atgcagccat ttcaagccta aagggcattg gtccttatac
    27421 tgctggagca atttccagta ttgcttttaa tttgccagaa ccagcggtag atggcaatgt
    27481 gatgcgggtt ctcagccgct tgtttgaggt tgattatgac attggtcttc ctgccaatcg
    27541 caagattttc caagcgatga tggagctatt gattgattca gagcgaccgg gcgatttcaa
    27601 ccaagctcta atggatctag ggtcggatat tgaatcgcca gttaatccac gtccccagga
    27661 cagcccagtc aaagccttta gcgcagccta cttaaacggt acaatggata agtatccaat
    27721 caaagcacca aagaaaaagc cgattcccgt ggcctaccag ggatttctca tcaggaataa
    27781 agacaatcaa tttttattgg aaaaaaataa tgaagcaggt cttctatcag gtttctggtc
    27841 ttttccgctt ttggaaaaag gagcaatcgt tgacaaacaa gtctctctct ttgaagttgc
    27901 agaagaagtt gttcagccag atattcggca gagctttacg gaactttatg gtctgactgt
    27961 tgattggcaa gagcaagaat ttggcatcgt ccagcacatt tttagtcacc gcaaatggca
    28021 gatagaaatg gtagaaggtg tggcagaaac acttaacctt ccagaatcaa aagaattgaa
    28081 atgggtttct gtagaagatt ttcctaccta cccatttgct aagccgcaac aaaaaatgtg
    28141 ggaaaacttt atcaaggaaa aagaaaagca aaaaagttga ctttggagca cataattatt
    28201 tgaaagcgtt ttataatagt ggtataatct aattgaaaaa aggaaatagt tagttaagat
    28261 gttgaacgcc atctgaattg ctgaaaggag ttctttagcg ttcgtagaag tgtatatact
    28321 attagccatc tttctctaat aaaaagagag ggatgctagt aggggaaaag tccgttatcc
    28381 ctgttttata tctatttgtg atatccattg tcaaatgcat agcattaact cattatttag
    28441 ccttgctacc cggttcaatc agaagtaggc taagattatt cgtgtcgtaa ctactatgtg
    28501 ttcaagatgt tgtaactttt gaacataacc ttagaaaatc acaaaaacct ctagcgattt
    28561 tcatcataat aagcaatctc cacactttag acaaatagta agaggacaat caaagacata
    28621 agggtagcag aataattatt taatcattaa cttgttgtca aataactatc tggtaatgga
    28681 cttttccaat ttgacatata aaaaggaggc tgtcatagcc tccttttact gtgcttttca
    28741 atttgttttc agtaggaaaa aacgccagct atacggacag actttccaaa actagatgga
    28801 tgaatgtagc atatataact agtgattaac taggcttaaa aatcaatctg gactataaat
    28861 atctacaact tgaccaatag gtcgaatatc gtcttctggg ctaaaataga tatcatcata
    28921 gtcagaattg agtgattgca aatagtcacc tttgaacttt ttaacaaaat tttccccatt
    28981 gactgaaaaa attccaatcg tatttagagg aatatgagga gttaggcgaa tgaagagata
    29041 gtctccatcc tcgatatgcg gagccataga atctcccaca acctgagcga ttgtatcata
    29101 agattggtta tctggaatct catcgttata gaatgataca agattgttca tatctgtatc
    29161 ctgccagtaa cctgtaccgg cagaaacctt accaggaaca ggtaattcga ttcgctcccg
    29221 atagtcatcc aagtgaagaa tagaagcaga aggagtaact gaggcagttt gcatagctgc
    29281 taactgttct tgaccaaaag ttaaccattg tgcatggaaa tcacctttta gttcattgtc
    29341 caaggttaga acctctggat gaataggctg ttgaaagagt ttaaattggg aaggagtaat
    29401 cgttaaagct atatcctgat tggaatctag ttgctcgatt agctcaccaa ccgatatagc
    29461 catgccctta gcgacttttt ctagcgtatc catcgttggc aggagagctt ttttggtttt
    29521 gggatgctgg ttcttttcca acatagaaat ataacctttt gttaaaccag ataattcagc
    29581 gaatttatcc attgataatt tattcttgct tcggtattct tttaaaatat cacctaaaat
    29641 catgattgtc tccttatctg tttaactaat tataccatta aaaaatattt tttgcaaatt
    29701 ttgtttaacg tgtttaacaa aaaatcaaaa cggtgttatg ataatctcac aaaaagaaaa
    29761 ataggagtcg caaatgaaaa ggattacaga gatttcttgg aatgatattt ataaagagtg
    29821 ggaaacctat gctaatcatt ttggtttggc gactccgata aatactgaaa aattgcgaaa
    29881 tcagaaatcg aaggattttg gaaaaggaag tctgattacg ctggacttat tagccgatta
    29941 cgatactgat tttgagaaga ccgcagctat ttgggtagct ttattttgta gagatttaat
    30001 acaagattac gcatatttac taaatggtag agcctatctt acagtcaatc agatttattt
    30061 tcaggcactc aaacaattcc agtcagaagc ggtaatatgg tcaaaacctc tcacatgatt
    30121 gcaaccgaag ttatttgtat cttatcgttt gttggaaaat cttgatttga gtcattattc
    30181 ttgtgtagtt gagttagcaa tgttgtaggc tagtatggtt cggacacaga tattagaaaa
    30241 gtaattatag taggagaatg aaaatgttta atttgttgaa taagaaagct gaagtatcga
    30301 aagttgcaga gtattggaat gataccttga tagaaagagg aattttgagc gctaatgaat
    30361 tgctcgaagg aaaatgctgg agatgtaaaa gttctcatgg tgtaaatatg tgtcagattg
    30421 tatcaagcaa atggagcaag gatacgagcc tggctaatca gatggtccta tgtctatcct
    30481 gtcagcatga aaaacctaat gtagctgata cagaaattgt gtggcaatgg ttagaagttg
    30541 agaataatga acgttactgg actctacaag gtatggcaga atatgagaaa atgtataaaa
    30601 aatcagtact tcaagagtta tgggatatgg gaattcgaga tggtgaagaa gtcgatacgc
    30661 ttgtaaataa agtaactagc ctttctcgta agaatgatat tgttttaaat agagcaacct
    30721 tagcaggatt atttcgctgt gaaatcgaac aaatgcgtcg aaaggcattt ctaaattgga
    30781 caggaatttt taagctagtc agttaaccga tacagttgta ggaaaacatc tcatgctgat
    30841 tggagtaaca gataaataaa aagcgcatca gcttagaatc ttaaagaaag aagtctaatg
    30901 atgcgtttat agggttatat ttcagctaat aaaattggag tgaatgtttt tgaattatag
    30961 ctcaaaacgt taatccaaac gttatggcga caacatttgt gccgactttt tggttcaaat
    31021 tggttcaaat gtttactcgc ttaatgaatt caataaattt aaggcctcag catcttgctg
    31081 gtgtcttttt tctggcatca attctagata atactgttgt gttgttaaga tagagttatg
    31141 acctagacga cgagaaatat agtctaggct aatatctttt gaaaagagaa atgaggcatg
    31201 cgtgtcacga agtccatgaa atgtcgtttt tgttaatccc aactgtttta acagcttttg
    31261 aagttgacta gcttgcttga atccatttca atcaaagata tagccttctt ttatttgtgc
    31321 aagctttgtc acagcttgat aaacatcttc gttgatggaa atatcacgct tagaatattt
    31381 ggttttaagc tgggcatcgt cattagttgg actaattgat cgaagaattt tgataccata
    31441 ttcaaaaata tcttcttttt taattcctaa aagttctccg cgccttgctc ctgtctcaag
    31501 ggcgagagca acaagaacat taaattcatc ctcagtatga cttaggcagt attgtctgag
    31561 ttttttaaat tctgtgatag atagtggtat atttcgttta ggttgttctt gtccttttga
    31621 tttcaaaaga tgaccaaaat cattactaat caaaccacga gcatacgcat attttaatga
    31681 accatggatt ttaagaacaa gttcttttac tgttttttta gagtgggttt cagcgtattg
    31741 gtcgattttc ttttgcatga cgagatcgtc aaggtgttta agttgaatac catcaaaaag
    31801 gtcatcaact attacgagag ttcgtttata gttaataaag gtggcttcgc gaacgtcagt
    31861 tttcttgacc gtatggaccc aatttctata aaaatcagga aatagggtgg agcgttcggc
    31921 aatgtttttg ccacgacctt tttcaagttc catttctaat gtccaaagct cagcatcttt
    31981 tctgttgcta aaggttttag tttctcgttt atattctcct ttcttataaa gtgatacagt
    32041 tgcacggtaa gagttaccac gttttgttat tgttgacatt ttatcagcct ttctataaaa
    32101 aatgattgat aaaatagact agtcacatat aggatatatg aaaaatctaa ttttatcaat
    32161 cattatccgt caatcgcagt ggctttcaat aaatttaacc agttttgact tcaaatagcg
    32221 ctcttgtttt cccaccataa agcattgaaa gtctgggtga cttctaatgt acttaccaaa
    32281 tgatttagga tctattccaa gtagttccgc tacttgttgt ctatttaaca gaagaggaga
    32341 attattttga ggtaacatat aaaattcctt tcattttcta gatataagta ttatgccaca
    32401 tgtgcaacaa atcgaggctt gatttttgaa aaatgtacaa tgtttcctaa cgtttcaata
    32461 aaatataagc ataggaatgt ggaaattcct ctggtctatt gtgtcccaga gcctttgtta
    32521 caattttaca agcttttctg tcgagcgaga tgccaactaa ctctttacgc agatggataa
    32581 tttctttacg atttctaatc ttggaaattt cgcgtgctac actgcgataa acacgctctg
    32641 catactctgc aggatatttg tgtgacttta atgctgttgg aactttcttt ccatcaaaat
    32701 cgtcgaggat taaatctttg ggaacatgaa agactttctt ttttcctgct cgttggaaaa
    32761 tagcgactaa ccactcttcc tcctcttgac tagtggccat gattggagac cagcgatctc
    32821 tgcgtccttt tgtgtgatgc ttatggccgg ctaaatttaa ataccaacgg ccatcacggc
    32881 cgcgttgcag agcatcgcca gtgacgtgga ttaattcact tttgcgtaag cctgtcgagg
    32941 taactacttt atgccagtag tcgttatttt tgttggataa acgatagtct ttatgtaata
    33001 cacgattgtt catacgattc gcacgagtac gtggttgtgt agcgatgaaa ttagttgagg
    33061 aaactccgag aactttggcc aatgctactt tgtaggtagc ttgtgtatat ggacttaaac
    33121 caatctctat acaatattgt aagtattgat tgataagttc tatccaacct tccgtatctt
    33181 tttcaacatt acctaatgcc attaactgtt ctggcgaaat gttaattgaa acccattttg
    33241 caaaacaatg ctatgaacct gaatagttat ggagtgtacg atgagtatgg attaactcaa
    33301 tgctttcttt tttccttgca gtcggttcta acgaaccgat gttttgcgaa ctgcgcaaaa
    33361 cctgctcgcg aagattgctc gcataataaa gttgtaatta tcatttaaaa taatgttcaa
    33421 aattccaaca tattcttgtt tatttttgat ataatgtaaa aaaacaacaa aggattaaac
    33481 atgaataaac gagaacgact agaagaaatt acacgattgg taaacaaaaa aggcacagtt
    33541 cgaatttctg agatagtaga attgctaaat gttactgata tgactgttcg acgtgatttc
    33601 attgaattgg aagagcaagg tgtcttaaca aaaattcatg gcggtgctag aagtaataag
    33661 gcttttcaat atcgagaata ttcccattct gagaaacaca ttcagaataa ggaagccaag
    33721 caagagatag cggaaagggc tgcacaactg atagaagatg gagacacggt atttttaggt
    33781 ccaggaacaa cagtggcctt tctggctgag gccattaaaa atcttcgcct aactgtcatc
    33841 acaaattgta tgcctgtttt tactatccta tcacaaaaga agacagagga ttttcaagtc
    33901 tttctccttg gaggagaata tcggcaagtg acagaatctt ttgtaggaga aattaccaat
    33961 acaagtttag aaaaaatgcg attcagcaag attttctttt caggtaacgg acttaaggga
    34021 actgatgtca tgacctctac cctagcggaa gcctatacgc aaaatattgc cattaaacat
    34081 tctttagaaa aatatctact gctggatgcc acgaaaattg gaaaagatga ttttacttct
    34141 ttttgtgatt tgaatgatgc aactgctcta gtgacagata tgaatgcaaa ggatgaaaat
    34201 taccaattat taagtaatca cattgaaatt atttctacaa aatcataaag tta
//
LOCUS       DBNFCO010000012        32695 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.012, whole genome shotgun sequence.
ACCESSION   DBNFCO010000012 DBNFCO010000000
VERSION     DBNFCO010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 32695)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32695)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32695
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.012"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            114..563
                     /locus_tag="AC1PIV_000502"
     CDS             114..563
                     /locus_tag="AC1PIV_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HIP6611550.1"
                     /translation="MGHTIADFRNLLNQIEQISETIAKEYDVEHLAGPQGWALRFIAE
                     RSEAETFVKDIEAELKISKSVASNLVKRMEKNGFIQVLPSKVDKRFKQLVLTEKGQGK
                     ICHLKAFHEEMHHSLFWGIQKEDFDLVKQVGNQLKVNIQRYKEKNHV"
     gene            556..2262
                     /locus_tag="AC1PIV_000503"
     CDS             556..2262
                     /locus_tag="AC1PIV_000503"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIP6611551.1"
                     /translation="MFKEAILRYKWYALASVLLTSIVVATTLMQPSYLQDVLTAVLAN
                     DKDEIVRVGKLLLIIAGIGLLAGLVNTIAAAKISQGVSADIREKTFRKIQSFSYANIE
                     EFNAGNLVVRMTNDVNQIQNLVMMLFTVLMRVPLLFVGAFIMAVRTMPELWWMIILMV
                     VLIMAIMAVVMGQMGPRFGKFQSLMDKMNSIAKENLRGIRVVKSFVQEKNQYAKFKKV
                     SNELLDLNLFIGYGFAILQPLMMFISYMAIFASLYLVSGMLETNLEAVGGFTSFMSYL
                     MQIMFAIIMTSFMGMQASRAAISIKRISEVLDTEPAMTFKDVADEELTGKIVFDNVSF
                     TYPHDTEPTLKNISFEIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQEGTVSIGGRDL
                     KEVSKNTLRDTVSIVLQKAILFSGTIADNLRQGAPGADLQRLERAAGIAQAKEFIDRL
                     DDTYESQVEERGNNFSGGQKQRMSIARGVIGEPKVLVLDDSTSALDAKSEKLVQEALN
                     HDLKGTTTVIVAQKISSVVKADKILVLDEGRLIGQGTHAELVATNDVYREIYETQKGR
                     EE"
     gene            2263..4047
                     /locus_tag="AC1PIV_000504"
     CDS             2263..4047
                     /locus_tag="AC1PIV_000504"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIP6611552.1"
                     /translation="MKTLRFFWFYFKRYKLSFAVIFLAIVAATYLQVKTPVFLGNAIA
                     EMGKIGQAYFMANQAGQADFQPDMADFNGVMLNLFFAYAATVVASLIYTLLFTRIVAH
                     STNRMRKGLFGKLERLTVAFFDSHKDGDILSRFTSDLDNIQNAFNQSLTQVVTNIALY
                     VGMVIMMFRQDTRLALVTIASTPVALIALVVIIRLSRKYTDKQQAAVSKLNAYMDEKI
                     SGQKAIIVQGVQEETIDGFLELNEEVRRTTFKGRLFGGILFPFMNGMSLVNTAIVIFA
                     GSSIVLNDSSLETAAALGLVVTFVQYSQQYYQPIMQVAASWAELQLAFTGAHRIQEMF
                     DEPEEVRPQNAPLFTELKEGVEIKDIDFGYLPGQKVLDKVSISAPKGKMVAVVGPTGS
                     GKTTIMNLINRFYDVNGGSVAFDGRDIREYDLDSLRNKVGIVLQESVLFSGTIADNIR
                     FGDESISQEMVETAARATHIHDFIMSLPEGYETFVTDDENVFSTGQKQLISIARTLLT
                     DPQVLILDEATSNVDTVTEAKIQKAMEAIIAGRTSFVIAHRLKTILNADEIIVLKDGK
                     VIEQGNHSQLLKLNGFYAELYHNQFVFE"
     gene            4153..4596
                     /locus_tag="AC1PIV_000505"
     CDS             4153..4596
                     /locus_tag="AC1PIV_000505"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HIP6611553.1"
                     /translation="MKIRGFELVSQFTDENLLPKRETAHAAGYDLKAAETVSLEPGEI
                     KLVPTGVKAYMQANEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPANEGHIFAQM
                     RNITEETVVVEAGERIVQAVFAPFLLADGDQADGVRTGGFGSTGK"
     gene            4603..5136
                     /locus_tag="AC1PIV_000506"
     CDS             4603..5136
                     /locus_tag="AC1PIV_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HIP6611554.1"
                     /translation="MQILFVRHSEPDYSMFDQHDNPRLYAGFGRDLAPLTEKGRTLAQ
                     EIASNPIFSQAQVVVASSVTRALETATYIAHAQQLPLMVEPFFHEWRPDMTGQNASQD
                     EAVLAHRLFLENSGAVPESSPVRYETAAEMRERFLQALGKYKAYDRIVIVCHGMLIRQ
                     FVPKETIAYCEILEYTL"
     gene            5143..6510
                     /gene="radA"
                     /locus_tag="AC1PIV_000507"
     CDS             5143..6510
                     /gene="radA"
                     /locus_tag="AC1PIV_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HIP6611555.1"
                     /translation="MTIAKKKTTFVCQSCEYHSPKYLGRCPNCGSWSSFVEEVEVAEV
                     KNERVSLTGEKTRPMKLNEVSSIQVARTKTNMEEFNRVLGGGVVPGSLVLIGGDPGIG
                     KSTLLLQVSTQLSTIGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSIRTE
                     IEKIKPDFLIIDSIQTIMSPDISSVQGSVSQVREVTNELMQIAKTNNIATFIVGHMTK
                     EGTLAGPRTLEHMVDTVLYFEGERQHTFRILRAVKNRFGSTNEIGIFEMQSQGLVEVL
                     NPSEVFLEERLDGATGSAIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRAS
                     LIMAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVALASSYKDKPTNPQECFM
                     GEIGLTGEIRRVNRIEQRINEAAKLGFTKVYAPKNSLTGIKVPKEITVIGVTTIGEVL
                     QKVFN"
     gene            6634..7128
                     /locus_tag="AC1PIV_000508"
     CDS             6634..7128
                     /locus_tag="AC1PIV_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004089 - carbonate dehydratase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-class carbonic anhydrase"
                     /protein_id="HIP6611556.1"
                     /translation="MSYFQNFMKANKAYVDLHGDYHLPLRPKTKVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQLGTWEIVVLHHTDCGAQTFTNEEF
                     AVQLKRDLGVDVAGQDFLPFTDIEESVREDIALLKQSPLIPDDVEISGAVYDVDTGRI
                     TEVI"
     gene            7336..8094
                     /locus_tag="AC1PIV_000509"
     CDS             7336..8094
                     /locus_tag="AC1PIV_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00266 family protein"
                     /protein_id="HIP6611557.1"
                     /translation="MSDNRMKYTIDSNMQFPLVEIALEAGESAYIQQGSMVYHTPSVT
                     LNTKLNARGGSGFGKLMGAIGRSMVSGESMFITQAISNSDDGKIALAPSTPGQVIALE
                     LGAEQYRLNDGAFLALDGSAQYKMERQSVGKAFFGGQGGLFVMTTEGHGTLLANAFGS
                     IKKLTLDGGSITIDNAHVVAWSRDLDYNIHMENGFLQSIGTGEGIVNTFTGYGEIYVQ
                     SLNIETFAQVIGNHIVGAGGDGGGGSTSLLDAIF"
     gene            8272..8718
                     /locus_tag="AC1PIV_000510"
     CDS             8272..8718
                     /locus_tag="AC1PIV_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HIP6611558.1"
                     /translation="MKVRIEFDDSLDQVEVVIRTSQLGPEIEQIQQALQQVSRPSLVF
                     YKGSSEYFLSLGDILFFETDGTKIFAHTGDDAYEVKMKLYELEEHLPIYFCRVAKSTI
                     VNSKLVYSLNKSFSGTSRISFYKTHKEVHVSRHYYHLLKEKLQEMR"
     gene            8723..9382
                     /locus_tag="AC1PIV_000511"
     CDS             8723..9382
                     /locus_tag="AC1PIV_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LiaF transmembrane domain-containing protein"
                     /protein_id="HIP6611559.1"
                     /translation="MKRLLIGAAVIGLAVLVLLRESLGLHLAMPFWTTVWFVLTFVTG
                     FHRLVKLDWLASIFCFGLAFIAANSVYEWVEFGTWNMFLSLVLLCLGLKLIFKPRKRR
                     LAHGVVTGVIGDKGRDTAFGSSTRYIHEENFIHDSVDVAFGSSTVYFDQAVILGNKAD
                     FHIDAAFSNITLYLPADWQAVVELDSAMSTTNNYASEPKEKILLVTGDMAFSTLNIYS
                     M"
     gene            9474..10754
                     /locus_tag="AC1PIV_000512"
     CDS             9474..10754
                     /locus_tag="AC1PIV_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HIP6611560.1"
                     /translation="MKKILKNATYLWVLTADMLSNFGDVVYYLALMNYVLLVPNSRLA
                     LAIVTFSEIFPSFMGLFTGYLADKTVNKISTIKLTLLFRVLLYLILGFCMGFEPALWI
                     VVVAASFNVFADFAGFYENGLYTPLGLRVAPKEEREQYSAFRQTVTSLLNIAFQALSA
                     LLVGLLSYQNLAFLNAGTFLASLLIMQLLTPAFRKLLTEQPLKIAEQPNQTEPKTKGP
                     GILASFKQAIVELRKIPEFRLVLITNPLINACGAILYPILVLLISEDPGLVFLNVETT
                     LALTILIFFIGHILGSTLVFTLFKNTSMVTLEVAATFSLLGVFVGMLLHQLPIIFFFL
                     TTMGISSGASGPKFNAKFVNSMPEEQLATIGGAVSTYFMLGQAFTRLLVSGLVLILTV
                     NQISGLFLAATGLLVLYVFYWLARNQKTPQNQSV"
     gene            10826..12280
                     /gene="gltX"
                     /locus_tag="AC1PIV_000513"
     CDS             10826..12280
                     /gene="gltX"
                     /locus_tag="AC1PIV_000513"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014917323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HIP6611561.1"
                     /translation="MTKPIRVRYAPSPTGLLHIGNARTALFNYLFARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGIDWDESPETHENYRQSERLDIYQKYVDQLLAEGKA
                     YKSYVTEEELAAERERQEAAGETPRYINEYLGMSEDEKTAYIAEREAAGIVPTVRLAV
                     NEAGIYKWNDIVKGEIEFEGGNIGGDWVIQKRDGYPTYNFAVVIDDYLMKISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRRKGYM
                     PEAVFNFIGLLGWNPGGEEEIFSREQFIQLFDENRLSKSPAAFDQKKMDWMSNEYIKN
                     ADLETIFNLAKPFLEEAGRLTDKAEKLVELYKPQMSSADEIVGLTDLFFSDFPELTAE
                     EKEVMAGETVPTVLNALKEKLEAMTDEDFQPDNIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPNTIYLLGREKSIQHIDNMLKSL"
     gene            12417..13793
                     /locus_tag="AC1PIV_000514"
     CDS             12417..13793
                     /locus_tag="AC1PIV_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0003333 - amino acid transmembrane
                     transport [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HIP6611562.1"
                     /translation="MENHNFENQGTFNREMNSRHLQMLSIGGVIGTGLFLSSGYTIAQ
                     AGPFGAVAAYLFGAVMVYLVMFSLGELSVAMPVTGSFHTYATKFISPGTGFMVAWMYW
                     LCWVVALASQFVGAAQLMQRWFPSVPIWIFATIFAVIVFGLNTLSVGWFAKAEDALSS
                     IKVYAIAAFIVLGTLAIFGILPFEGTNAAPLFTNITAQGLLPNGLVGLISVMLSVNYA
                     FSGVEMIGIAAGETDNPKKAVPQAIKSTIGLLVIFFVLTIVVLAALLPMSEAGVTEAP
                     FVLVLDKIGFPYAADIMNFIILTAILSASTSGLYASSRMLWSLANEGMISKELVKINK
                     HGVPMRGMILSMIGVVIALVASIYAEDTIFLALVSIAGFAVVIAWLAIPLAQIGFRRE
                     FLKNHSEDELEYKTPFSPTLPWITVVLLVISIIGIGWDPSQRAGLYFGVPFMIGCYIY
                     HYIRFKKW"
     gene            13806..14753
                     /gene="mmuM"
                     /locus_tag="AC1PIV_000515"
     CDS             13806..14753
                     /gene="mmuM"
                     /locus_tag="AC1PIV_000515"
                     /EC_number="2.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047150 - betaine-homocysteine
                     S-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homocysteine S-methyltransferase"
                     /protein_id="HIP6611563.1"
                     /translation="MGRFKELLEQKEYIILHGALGTELEFRGHDVSGKLWSAKYLLEN
                     PQYIKDIHKDYIRAGADLVTTSTYQATFEGLAEVGLSQAEAEELIRLTVDLAKEARDE
                     VWAELSEAEKVQRTYPLISGDVGPYAAYLANGAEYTGDYGNISLSELKDFHRRRIELL
                     LEQEAELLALETIPNVLEAQALVELLAEDFPEAEAYISFTSQDGQSISDGTSIEKIAE
                     LVNSSEQILAVGLNCTAPSLYPAFLSQLREKTDKPFVTYPNSGEVYDGATQTWKEKAD
                     DSHSLLDNTLEWHELGAKVVGGCCRTRPADIADLVAGLK"
     gene            complement(14803..15303)
                     /locus_tag="AC1PIV_000516"
     CDS             complement(14803..15303)
                     /locus_tag="AC1PIV_000516"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016817 - hydrolase activity, acting on
                     acid anhydrides [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0009132 - nucleoside diphosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HIP6611564.1"
                     /translation="MEIWNAYTADGHLTDHTLTRGESIPDGLYHLVVECIIRHHDGST
                     LFMKRDSTKPSYPDYYEATAGGSALFGEIAEQAILREVREETGIELTADQLRHHKHFV
                     AHDDQCIFHCYWAETDWDKVAIQLQANETSNYIWVQQENLKDFLETELVIPRQKDYVE
                     RLFLES"
     gene            15410..16285
                     /locus_tag="AC1PIV_000517"
     CDS             15410..16285
                     /locus_tag="AC1PIV_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HIP6611565.1"
                     /translation="MQPIIPHLWYDTEAKEAVAFYVDLFGGNVDWTYTITDTPSGDSD
                     LIQFQLGDMTLAAISAGPYFTLNESMSLMVNVADKDEVTRLYQALSEGGRILMPLGEY
                     PFSPYYVWLEDRFGLSWQLSYAPDLDKPYQFDICLLFSQEQVGLAQPMLDYYKDKLPQ
                     ASVGQLSYYGEGEAAVEAAKLNYAELLVAGQKMIVMDHGYGGVASFNEAFSFMVYVDS
                     QEEAESWYEKVSAVPEAEICGWAKDQFGISWQIVPRILMEAYDTANPEKVKAVNAAVM
                     TMKRLDIAAIQALLN"
     gene            16391..16915
                     /locus_tag="AC1PIV_000518"
     CDS             16391..16915
                     /locus_tag="AC1PIV_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HIP6611566.1"
                     /translation="MKATERRKKILSLLRESPYPLAANYLAKEFGVSRQVIVGDVALL
                     RAEGEAVLATPRGYLLQSSLPSTEGAYIRKIACQHGPEEVEKELTILLEGGAQILDVE
                     IEHPIYGLLSGKLNIASLEDRDHFLDALGQYQGVLLSNLTEGVHTHTVSFPSVQAYNE
                     LSAALKHAGILLEN"
     gene            16988..17536
                     /locus_tag="AC1PIV_000519"
     CDS             16988..17536
                     /locus_tag="AC1PIV_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611567.1"
                     /translation="MSQLTLSSKNSVKQLSISAILTAFAILIPLMMPIKIIIGPASYT
                     LASHIPLFIAMFISPATAIFVALGSSLGFFLAGFPIVIVFRALTHLFFLTLGAVLVKR
                     FPILMDSKRFLLLGIGLNLLHGLGEYIVVMVLTSGQQTSATYWITMLGLVGVGSAIHG
                     LLDFSLAYYFWKILKERKIYQP"
     gene            17730..18923
                     /locus_tag="AC1PIV_000520"
     CDS             17730..18923
                     /locus_tag="AC1PIV_000520"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004055 - argininosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006526 - L-arginine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HIP6611568.1"
                     /translation="MTKEKLILAYSGGLDTSVAIAWLKKDYDVIAVCMDVGEGKNLEF
                     IHDKALSIGAIESHVLDVKEEFAQEYVLPALQAHAYYEQKYPLVSALSRPLISKKLVE
                     MAHKTGATTIAHGCTGKGNDQVRFEVAIAALDPSLKVVAPVREWKWAREEEIIFAKEN
                     GVPVPADLDSPYSVDQNLWGRANECGVLENPWNEAPEDTFGITTSPENAPDTPEYVDI
                     EFKAGIPVAVNGEKLSLANLIQRLNVIAGKHGVGRIDHVENRLVGIKSREIYECPGAI
                     TLLTAHKEIEDLTLVREVSHFKPIVSNELSNLIYNGLWFNPATDALKAYLAQTQAVVN
                     GTAKVKLYKGSAKVVARKSPNSLYDEDLATYTSADTFDQDAAVGFIKLWGLPTKVNAE
                     IHKKS"
     gene            18937..20331
                     /gene="argH"
                     /locus_tag="AC1PIV_000521"
     CDS             18937..20331
                     /gene="argH"
                     /locus_tag="AC1PIV_000521"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004056 - argininosuccinate lyase activity
                     [Evidence IEA];
                     GO_process: GO:0042450 - L-arginine biosynthetic process
                     via ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HIP6611569.1"
                     /translation="MEAKKLWGGRFEASLEEWVEEFGASIRFDQKLAKYDIQGSLAHV
                     KMLGQTRIISQAEAQVIQAGLEELLEEYEAGKLVFDIRNEDIHMNIESLLTEKIGSVA
                     GKLHTARSRNDQVATDMHLYLKDTLFQVVDKLTNLRQILVDLAQEHVETIMPGYTHLQ
                     HAQPISFAQHLLAYYNMFSRDSERFAFNMQHTNVSPLGAAALAGTTFPIDRQMTSDLM
                     GFAKPYSNSLDAVSDRDFILEFLSNASILMMHMSRLCEEIINWCSYEYQFVTLSDTFS
                     TGSSIMPQKKNPDMAELIRGKTGRVYGNLVGLLTVMKSLPLTYNKDLQEDKEGMFDTA
                     ETVLISIDILAGMLKTMTVHKERMAQSTEKDFSNATELADYLASKGLPFRQAHEIVGK
                     LVLECSKAGHYLQDVSFETYQAISPLIQADIYDALSSKVAVSRRNSLGGTGFESIADQ
                     LKSAKEEIQNAKSL"
     gene            20402..20761
                     /gene="rnpA"
                     /locus_tag="AC1PIV_000522"
     CDS             20402..20761
                     /gene="rnpA"
                     /locus_tag="AC1PIV_000522"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HIP6611570.1"
                     /translation="MKKSYRVKRERDFNDIFTKGNNVANRRFVVYRLPKEQKHFRVGL
                     SVSKKLGNAVMRNKIKRRIRHILIECQHQLVADDFVIIARKGVEELSYQEMKQNLIHV
                     LKLAKLYQEGVVIEKES"
     gene            20745..21557
                     /locus_tag="AC1PIV_000523"
     CDS             20745..21557
                     /locus_tag="AC1PIV_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0032977 - membrane insertase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YidC/Oxa1 family membrane protein insertase"
                     /protein_id="HIP6611571.1"
                     /translation="MKKKVKWAGLLVASLIVLTACGTGPVTSQSTDAWDRLIYWFASI
                     IQFLSINGQIGIGIILFTILIRTLLLPLFQIQMNSSRKMQELQPQLKKLQAEYPGTDM
                     ESRQQLYEATQALYKENGVSMRASMIPLFIQMPILLALFQALTRVEALKVGHFLWLNL
                     GEPDPFFILPILAAVFTFLSSWLTNKSAIEKNMAMTIMTYVMPVMIFFFAVAAASGVA
                     LYWTVSNAYQVAQTLVFNNPFKIIAERQAKIDAEKERQAKIRRAQKKAQKKK"
     gene            21577..22572
                     /gene="jag"
                     /locus_tag="AC1PIV_000524"
     CDS             21577..22572
                     /gene="jag"
                     /locus_tag="AC1PIV_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding cell elongation regulator Jag/EloR"
                     /protein_id="HIP6611572.1"
                     /translation="MKFTGASVEEAIQNGLVELNIPRKKAHITVVAREKKGFLGFGKK
                     PAIVDIDVINETTVVKANQKAVRGVPSEINDLNEPVKSVSEATIDLGKVVAAVKEFEK
                     SGQTLDDDIKAQILKNEKEATTILEETGRIEILSEDLLTTTDATTSAKEDVNQEVISE
                     NQADNFADLDIKIEPQYDIEQVVSEVTAYVQEILDDMDVEARIDTSHNRRTINIQVDT
                     NEPGRVIGYHGKVLKALQLLAQNFLYNRYERNFYITINVNDYVEHRAEVLQGYAQKLA
                     ERVLAEQEAYHTDPMSSSERKIIHRIISKMDGLTSYSEGSEPNRYVVVDIEGNHD"
     gene            22740..22877
                     /gene="rpmH"
                     /locus_tag="AC1PIV_000525"
     CDS             22740..22877
                     /gene="rpmH"
                     /locus_tag="AC1PIV_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HIP6611573.1"
                     /translation="MKRTFQPSKIRRARKHGFRSRMATKNGRRVLAARRRKGRKVLTV
                     A"
     gene            22984..23766
                     /locus_tag="AC1PIV_000526"
     CDS             22984..23766
                     /locus_tag="AC1PIV_000526"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004536 - DNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HIP6611574.1"
                     /translation="MIQIFDTHTHLNVEQFDGRVQEELDFAKEMGVTLHNVVGFDRAT
                     IDKAMELADQHPEIYLTLGWHPTEAGTYDEEVENYLLKALQHPKVIALGEIGLDYYWM
                     TADKEIQARVFKRQMELAKQLDLPFVVHTRDALEDTYQIIKEVGVGPRGGIMHSFSGT
                     LEEAQAFMDLGMHISFSGVVTFKKAVELQEAAQALPLEKILVETDAPYLAPVPKRGRE
                     NRTGYTRYVVDMLAQLRNQSVEEVAAATYENARSLFRIDSEN"
     gene            23750..24319
                     /gene="rnmV"
                     /locus_tag="AC1PIV_000527"
     CDS             23750..24319
                     /gene="rnmV"
                     /locus_tag="AC1PIV_000527"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009910916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043822 - ribonuclease M5 activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HIP6611575.1"
                     /translation="MTQKIKIQEVLVVEGKDDTANLKRFYEVDTYETRGSAISDDDLE
                     RIEKLHDLRGVIIFTDPDYNGERIRKIIIQAIPTVKHAFLQRDEAAPKSKTKGRSLGI
                     EHASFEDLEKALAGVRGHYDDENNFDISQKTLIRLGLLMGGDSRKRREYLGEKLRIGY
                     CNGKQLLKRLELFGISLAEVEEAMESYHG"
     gene            24312..24680
                     /locus_tag="AC1PIV_000528"
     CDS             24312..24680
                     /locus_tag="AC1PIV_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611576.1"
                     /translation="MDRVYAVKCLVKNEFEPSYENYSSYEEVTYLLPADVLVWEDEQV
                     DKNKLADYLLGLVEDGYVNADGIWKQSRLFHIAGVQEMDDRVEFDGLAVEVYRWFYNF
                     ERPVTEEEFLNLYYFDDLGR"
     gene            24778..25065
                     /locus_tag="AC1PIV_000529"
     CDS             24778..25065
                     /locus_tag="AC1PIV_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin-antitoxin system antitoxin subunit"
                     /protein_id="HIP6611577.1"
                     /translation="MITINKDAQVNFKTDSRLLEKAKEVFAMNQLDLTAGFNLFLQNI
                     AVKNELPILTEEELEREELFLQLQKEIQENQQAIEAGHGISLESVKEKYGI"
     gene            25055..25384
                     /locus_tag="AC1PIV_000530"
     CDS             25055..25384
                     /locus_tag="AC1PIV_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0090729 - toxin activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HIP6611578.1"
                     /translation="MEFESYSVILAPAVEKELAVIYAYFSEQFSEEIAKRRIGMIVEA
                     LESLQIFPERGFNADNRFGKQIDPPHLTRGYVVGKDYIALYRVVKNEVRVGHLFATKS
                     DYVKLLK"
     gene            25391..25846
                     /locus_tag="AC1PIV_000531"
     CDS             25391..25846
                     /locus_tag="AC1PIV_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HIP6611579.1"
                     /translation="MSRTEQVILTNMCMITDGQQVLVQDRNSKKWPGVTFPGGHVEPN
                     ESIISSVIREIKEETGLTVSNLELCGIQNWTDPTDHYRYLVFCYKTSYFSGFIQSSDE
                     GEVFWIDRAELKNLQLADGFETMLEIFEQPQLTENFYWFEDGEWKVENR"
     gene            25922..26182
                     /locus_tag="AC1PIV_000532"
     CDS             25922..26182
                     /locus_tag="AC1PIV_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HIP6611580.1"
                     /translation="MEAIVYSHFRNHLKDYMKKVNDEFEPLVVVNKNPEEDIVVLSKS
                     EWDSLQETLAVARNTYLSQKVLRGMAKVKTGQTQERNLIEAD"
     gene            26184..26441
                     /locus_tag="AC1PIV_000533"
     CDS             26184..26441
                     /locus_tag="AC1PIV_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HIP6611581.1"
                     /translation="MGIHFTDDAWEDYLYWQGQDKKTLKRINKIIQDMQRHPFEGIAK
                     PEPLKYDYQGAWSRRIDAENRLIYMVEADRLCILSLKDHYR"
     gene            26455..26985
                     /locus_tag="AC1PIV_000534"
     CDS             26455..26985
                     /locus_tag="AC1PIV_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HIP6611582.1"
                     /translation="MKKVVLLRGVTPVGKNKIPKMSYLAEILTEAGLTSVQTYIQSGN
                     VVCETDILDEELSRLIHQTIKEKIGAELAIIVKHQMELTQAVAENSFGEGYDPSRVHL
                     VFTNDEINGEKLNKLLHQDFGDEELRLGSQCLYMYLPRDARKKKLNTNYLEKQLDITA
                     TMRKLSVISRLSEMAK"
     gene            27005..27877
                     /gene="rsmA"
                     /locus_tag="AC1PIV_000535"
     CDS             27005..27877
                     /gene="rsmA"
                     /locus_tag="AC1PIV_000535"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HIP6611583.1"
                     /translation="MRIADKNVTRAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DRNVNVIEIGPGIGALTEFLAENAAEVLAFEIDDRLIPILADTLGRFDNVTVVNQDIL
                     KTDLQTQIQNFKNPDLPIKVVANLPYYITTSILMHLIESKIPFSEFVVMMQREVADRI
                     SAEPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRREQPLVSVKD
                     EDFFFRVSKASFVHRRKTLWNNLTNHFGKSEEVKDKLTQALGMAELEASVRGEALSMA
                     DFARLSDSLQEVGL"
     gene            28242..29972
                     /locus_tag="AC1PIV_000536"
     CDS             28242..29972
                     /locus_tag="AC1PIV_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611584.1"
                     /translation="MLKKLLKKHPDIVAVTVFFLFSLTLLLPQILTKAVVTGDDIVFH
                     YNRFYDTAIQIKSGDFSYIMSLHGYQQSGRIVNALYGPYLAYLQGALLLLAGTWYRYQ
                     LLSNLLLGVLSATSLYFLMREVKVLYSLSVGLSMFFATTYSVQYWWVAQGFSSWGVAL
                     FPLCLIPAVRFLKTGKVPIFLMAGAVGLMLQIHMLSALFLILAYAILFSIGWLKSQDK
                     WNVMKDVLFSVGVFLILTVNIWLPLLYVNATNELAAPFINKKFIQSTVTWSKAYFLYF
                     PYSLPIIFATSLYFMLKKWKKQSVILRGLTVTFLVFFIFSTNLFPWQLFAGKGIGLVD
                     LIQFPFRFFLYANALLLTIVGLQLTDYEVRKKLFLGLTILSTIIGVGFTWDQYNQAVN
                     DQYNKAEFLQDMLHTTLYGTTEELRASLHSKNLGEFVQLAQKSTPDYVPVLSEKEENV
                     RAVNEAKSRYDRYRDQIILPNQQFNKQVFGDSLKISWSANQSEEIQIPIVIYRDSELT
                     LNGKRLGKMDYYLSTIGVPTVTSQKGKNTLILSYKQQWWLLPVIFISLTGWILWSIYY
                     TFIYRKSNIS"
     gene            29985..32429
                     /locus_tag="AC1PIV_000537"
     CDS             29985..32429
                     /locus_tag="AC1PIV_000537"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016772 - transferase activity,
                     transferring phosphorus-containing groups [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HIP6611585.1"
                     /translation="MKQIKLKATKQFILVMVMTVLLAMGRALLLSDVSFPLWFIPLPL
                     IAYLIFTFYVLVLLDKYEKFIKTKTFAKYVGYFLGFLYLINLVYRLNAKKYQPWNIFR
                     NNLFQFELLLMLALPVLLAFLWRKKTGIREKLSQWSANHLVPDGYLLLTSLLSLSPLA
                     ISYWKDSHYESLVEKGSYIEFFSQTPLFAPIHFIGTYIFLRYLHKAFVEFKANRTNVY
                     SMLFISLALATLSHIGYQASMAGATGSYFTRHLFPGAIVFQIACLFFLNVIISLVINR
                     QILSVAVIASLNVILVTANFLKFRYRSEPLTPNDFKWVGNLGMILSFISLRVVLVSLV
                     FIVLLVFIYRRIHKKYFQGRIVASIWKRLAGISVIVSLILGMGWAIRNEKDHKIAGWI
                     PILSQVNNWRNVDWKGYAFVARYRTLSFLWLQQLSKTSMEMPENYSEKTMKAIVKKYT
                     ALAEEINAERTGQLTDQTVIYILSESLADPRRIPGVTLSQNVLPNIEYIMSQTTSGLM
                     KSDHYGGGTANIEFQVYSGLPFYNYSSSISSVYLDVAPNMKKLPSISDLYPADNRIAI
                     HPYYDTSYNRNSIYKQLGIEQFYTLNSAKYPLTVTAEDYQGNFVSDKKTYDLILDQVR
                     SADTSFVSAITMQNHVQWNSLEPAGIIASGEGFTAEENENLTSYVRLLSFTDQATRDF
                     LDQLKTLDKKVTVVFYGDHLPGLYPESAFVTDPSAQYKTDYFVWSNFDTAKYNYELVN
                     SSDMNALMLETTNNKVSPYYALLTEVLHKDRVGQAERDAKVAEELKLVQYDLSTGKGY
                     LLKYKDFFKVATETTE"
BASE COUNT         8947 a         6631 c         7753 g         9364 t
ORIGIN      
        1 gatgctgaaa taacaaaata ttttcagaaa agagcaaacg aaataattga caatagttct
       61 taagagaact ataatagttc tcatggtaat tattttcgta gaaaggagct gtcatgggac
      121 atactattgc agattttcgg aacttgctca atcagattga acaaattagt gaaaccattg
      181 caaaagaata cgatgtggag cacttggctg gtccacaggg ctgggccttg cgcttcattg
      241 cggaacggtc ggaagccgaa acctttgtaa aagatataga agcggaatta aagatttcca
      301 aatcggttgc cagcaatctg gtcaagagaa tggagaaaaa tggctttatc caagtccttc
      361 cctctaaggt tgacaaacgc ttcaaacagc tggttttgac agagaaggga caagggaaga
      421 tatgtcacct gaaagctttt catgaagaaa tgcaccattc acttttttgg ggcattcaaa
      481 aagaggactt tgacttggtt aaacaggtgg gcaatcaatt aaaagtaaat attcaacgct
      541 ataaggagaa gaatcatgtt taaagaagcc attttacgtt ataaatggta cgccttggca
      601 tcggtcttgc tgacgtcaat tgtcgtagca acgaccttga tgcaacctag ttatttgcag
      661 gatgttttga cagcagtctt ggccaatgac aaggatgaaa ttgttcgtgt gggcaaatta
      721 ctgctgatta ttgctggaat tggtcttttg gcagggcttg tcaataccat tgctgcagca
      781 aaaatttcac aaggggtatc tgcagatatt cgtgagaaga cctttcggaa gatccaaagc
      841 ttctcttatg ctaatatcga agagtttaac gcagggaacc tggttgttcg gatgactaac
      901 gatgtcaatc aaatccagaa ccttgtcatg atgctcttta cagtgttgat gcgggttcca
      961 ttgctgtttg tcggagcctt tatcatggca gtgcggacca tgccagaact ctggtggatg
     1021 attattctca tggtggtctt gattatggct attatggcag ttgtcatggg gcaaatggga
     1081 ccacgttttg ggaaattcca gtccctcatg gacaagatga acagtattgc taaggaaaac
     1141 ctccgtggga ttcgtgtggt taagtctttt gtacaggaaa aaaatcagta tgccaagttc
     1201 aagaaagtat ccaatgaact cttggacctc aacctcttta tcggctatgg ttttgctatc
     1261 ttgcaaccct tgatgatgtt tatctcttac atggcgattt ttgcatcgct ctacttggtg
     1321 tccgggatgt tggaaaccaa cttggaggca gtcggtggct ttacttcctt tatgagttac
     1381 ctcatgcaaa tcatgtttgc cattatcatg actagcttca tggggatgca ggcttcacgt
     1441 gctgctattt ctattaagcg gatcagcgag gtcttggata cagaacctgc tatgaccttc
     1501 aaggatgtgg cggatgaaga attgactggt aagattgttt ttgacaatgt tagctttacc
     1561 tatccacacg atacggagcc gactttgaaa aatatctcat ttgagattga gccaggtcaa
     1621 atggtcggtg tggttggtgc aacaggtgcg ggtaaatcca ctcttgctca actgattccg
     1681 cgtttgtttg acccgcaaga aggaacggtg tccatcggtg gtcgggactt gaaagaagtc
     1741 agcaagaaca ccctgcgtga tacggtatcg attgtcttgc aaaaggctat tctcttctcg
     1801 ggaaccattg cggacaacct gcgtcaaggg gcacctggtg ctgatttgca acgcttggag
     1861 cgggccgcag gtattgccca agccaaagaa tttatcgacc gcttggatga tacctatgag
     1921 agccaagtag aagaacgtgg aaataacttc tctggtggcc agaagcagcg gatgtccatt
     1981 gctcgtgggg tgattggtga gcctaaggtt ttggtcttgg atgactcgac ttctgccctg
     2041 gatgccaagt ctgagaaact ggtccaagag gctctcaacc atgatttgaa ggggacaacc
     2101 actgtcatcg ttgcccagaa gatttcttct gttgtcaaag ctgataagat tttggttctt
     2161 gacgaaggcc gtctaattgg acaaggaact cacgctgagt tggtagcgac gaacgatgtt
     2221 taccgtgaaa tctacgaaac acagaaaggg agggaggaat agatgaagac gttacgtttt
     2281 ttctggtttt attttaaacg ctataaactg tcctttgctg tgatttttct agccattgtg
     2341 gcagcgacct acctgcaggt taagacacct gttttccttg gaaatgccat tgcggagatg
     2401 gggaaaatcg ggcaggctta ctttatggcc aatcaagctg gtcaggctga ctttcagcca
     2461 gacatggctg attttaacgg ggttatgctc aatcttttct ttgcctatgc ggcgacggtt
     2521 gtggcttcct tgatttacac tctcctcttc acgcgtatcg tggctcattc gaccaaccgt
     2581 atgcgtaagg gcttgtttgg caaactggaa cgcttgacag ttgccttctt tgatagccac
     2641 aaggacgggg atatactttc tcgctttacc agtgatttgg acaatatcca aaacgctttc
     2701 aaccagtcct tgacccaagt ggtgaccaac atcgctcttt atgttggtat ggtcatcatg
     2761 atgttccgtc aggatactcg cttggccttg gtgaccattg cttctacgcc agttgccttg
     2821 attgccttgg tcgttatcat ccgcctatca cggaaatata cggataagca acaggctgcg
     2881 gtgtctaaac tcaatgccta catggacgag aaaatttctg gacaaaaagc gattattgta
     2941 caaggtgtgc aggaagagac aattgatggt ttcttggagc tcaatgaaga agttcgtcgc
     3001 acaactttca agggacgctt gtttggtggg attctcttcc catttatgaa tggtatgagt
     3061 ttggtcaata cggccattgt tatctttgca ggttccagca ttgttctcaa tgacagctca
     3121 ctggaaacag ctgccgcact tggtctggtg gtgacttttg ttcaatactc gcaacagtat
     3181 taccagccaa tcatgcaggt tgctgccagc tgggcagaat tgcagctagc tttcacagga
     3241 gctcatcgta ttcaggaaat gtttgatgag cctgaggaag ttcgtcctca aaacgctccg
     3301 ctatttaccg aattaaaaga aggtgttgaa attaaggaca tcgactttgg ctacttgcca
     3361 ggtcagaagg tcttggacaa ggtgtctatc tctgctccta agggtaagat ggtggcggtc
     3421 gttggtccga cgggatctgg taagactacc attatgaact tgattaaccg cttctacgat
     3481 gtcaatggtg gtagtgtggc ctttgatggt cgcgatattc gggaatatga tttggatagc
     3541 ttgcggaata aggtcggtat cgtcttgcag gagtcggtgt tattctcggg tactattgcg
     3601 gacaatattc gctttggtga tgagagcatt tcgcaggaaa tggtggaaac cgcagctcgt
     3661 gccacccata tccacgactt catcatgagc ttgccagagg gctatgaaac ctttgtgacc
     3721 gatgatgaga atgtcttctc aacaggtcag aaacagttga tttccattgc ccgtacgctt
     3781 ttgacagacc cacaagtctt gattttggac gaagcaacct caaacgttga taccgtaacg
     3841 gaggccaaaa ttcaaaaggc tatggaggcc attatcgcag gacggactag cttcgtcatt
     3901 gcccaccgcc tcaaaaccat tctcaatgcg gatgaaatca tcgtcctcaa ggatggaaag
     3961 gttatcgagc aaggcaacca cagccaactt ctcaaactaa atggcttcta cgccgaactt
     4021 taccacaacc agtttgtgtt tgaataaagt tgaaaacccc agccactagg ttggagtttt
     4081 gcttttagcc tgcgaataaa ttataataga gagcgtatgt attatgcatg aagaaattga
     4141 agggaaacta ctatgaaaat ccgtggattc gaactggtca gccagtttac tgatgaaaac
     4201 ttattgccaa aacgtgagac cgctcatgca gcaggttatg acctgaaagc tgcagaaact
     4261 gtcagcttgg agccaggcga gattaagctg gtgccgacag gtgtaaaggc ctatatgcag
     4321 gcaaacgaag tcctctatct ctacgaccgc tcgtccaatc ctcgcaagaa gggtctggtc
     4381 ctgattaact cggttggggt tatcgacggg gactactacg gcaatccagc caacgaaggc
     4441 cacatctttg cccagatgcg aaacatcaca gaggaaaccg tcgtggtgga agctggtgag
     4501 cggattgtgc aggctgtttt tgcccccttc ctcttggctg acggtgatca ggccgacggc
     4561 gttcggacgg gcggatttgg atcgacaggg aaatagacta ctatgcagat tctctttgtg
     4621 cggcattccg aacccgacta cagtatgttt gaccagcatg ataatcctcg gctgtatgca
     4681 ggttttggac gggatttggc tcctttaact gaaaaggggc ggactttagc tcaggaaatt
     4741 gctagtaatc ctatcttttc ccaagctcaa gtagtcgtcg cttcaagcgt cacacgggcc
     4801 ttggaaactg cgacctacat tgctcatgcc cagcaactac ctcttatggt cgagcccttt
     4861 tttcatgaat ggcgaccaga tatgacgggg caaaatgcca gtcaagacga ggctgtctta
     4921 gctcatcgat tatttttgga aaatagcgga gcggtgcctg agtcttcacc tgttcgctat
     4981 gagactgctg cggagatgag agagcgattt ttacaggccc ttggaaaata caaagcctat
     5041 gaccgaatcg ttatcgtctg tcacggtatg ctgatacgcc agtttgttcc caaagaaact
     5101 atagcctact gcgaaatcct agaatacact ctataggagg aaatgaccat cgctaagaaa
     5161 aaaacaacct ttgtctgtca atcctgcgag taccactcgc ccaagtacct gggtcgttgc
     5221 cccaactgtg gctcctggtc tagctttgtc gaggaagtgg aagtcgctga agtcaagaac
     5281 gagcgggtca gcctgacagg tgagaagacc cgtcccatga aactcaatga agtgtcatcc
     5341 attcaagtgg ctcgcactaa gactaacatg gaggagttca accgcgtcct cggtggcggt
     5401 gtggtaccgg ggagtctagt tctcattggc ggcgatccag ggattggcaa gtccaccttg
     5461 ctcctgcaag tatccactca gctgtctacc attggcaccg tcctctatgt gtcgggggaa
     5521 gagtctgccc agcagattaa gttgcgagcg gaacgcttgg gcgacattga cagcgagttc
     5581 tatctctatg cagagaccaa tatgcagagc attcggaccg agattgagaa aatcaagcca
     5641 gatttcctga ttatcgactc tatccagacc attatgagtc ctgacatctc cagcgtgcaa
     5701 ggctctgtca gtcaggtacg tgaagtgacc aatgagctca tgcagattgc caagaccaac
     5761 aatatcgcaa cctttatcgt cggccacatg accaaggaag gaaccttggc tggaccgcgg
     5821 accttggagc acatggtaga caccgttctc tattttgaag gcgagcggca gcacaccttc
     5881 cgtatcttgc gggcggtcaa aaatcgcttc ggctccacca atgaaatcgg catttttgaa
     5941 atgcagtcgc agggcttggt cgaagtcctc aatccaagtg aggtctttct ggaagagcgt
     6001 ctggacggag cgactggctc ggctattgtc gtgaccatgg agggtacccg cccaatcctt
     6061 gcggaagtgc aggctctggt gacgccgact atgtttggca atgccaagcg gaccacgaca
     6121 ggactggatt tcaaccgtgc tagcttgatt atggcggttt tggaaaaacg ggcaggcctg
     6181 ctgctccaaa accaagacgc ctacctcaaa tcagcaggcg gtgtcaaact ggatgagcca
     6241 gctattgacc tggcagtcgc agttgccctt gcttccagtt acaaggacaa gccaaccaac
     6301 ccacaagagt gctttatggg cgaaatcggt ctgacagggg aaatccgccg cgtcaatcgt
     6361 attgaacaac ggattaacga agccgccaaa ttgggcttta ccaaggtcta tgcccccaaa
     6421 aattccctga caggtatcaa ggtgcccaag gaaatcaccg ttatcggcgt gaccaccatt
     6481 ggcgaagtct tgcagaaagt attcaactga tgaaatcatt cgggagttac agctagtcgc
     6541 tcctcttttt gcgacaaata gtcgggaatg tgataagcta ggtctaacct atttctgaaa
     6601 atttcagaaa ttctcatcag acaaggaggt cctatgtctt attttcaaaa ctttatgaag
     6661 gccaacaagg cctatgttga cctgcatggt gattaccatt tgcctcttcg tccaaagacc
     6721 aaggtggcta tcgtgacctg tatggactca cggcttcacg tggcgcaggc cttaggcttg
     6781 gctctggggg atgctcacat tctgcggaat gcgggtgggc gcgtgacaga agacatgatt
     6841 cgctcgctag tcatttccca gcagcagctc ggtacatggg aaatcgttgt cctccaccat
     6901 acagactgcg gtgcacagac ctttaccaat gaagaatttg cagtccaact caagcgagat
     6961 ttgggagtgg atgtggctgg tcaggacttt cttcctttta cagacattga agaaagcgtg
     7021 cgggaggata ttgctctctt gaaacaatct ccgctcatac ctgacgacgt tgaaatttct
     7081 ggtgcggttt atgatgtgga tacgggtcgt ataacagaag ttatatagga atgctcagga
     7141 agttcggttt ttcctgtaaa ttttatctga atgaccggga aatccttgac aagttttttt
     7201 gaatgagata aaattgtatt atcacaacag aacaaatgaa gagataaatg atacttggtt
     7261 tattttagct tgttctaggt ttattatggc tatcctgtgg ttaacaggac ctttcgtaaa
     7321 aaataggagt caactatgtc agacaatcgg atgaaatata ctatcgatag taatatgcag
     7381 tttcctttgg tggaaatcgc cttggaagct ggtgaatcag cttatattca acaggggagc
     7441 atggtctacc atacgccgag tgtgaccttg aataccaagc tcaatgcgcg tggtggttca
     7501 ggttttggta aattgatggg ggccatcggt cggtcaatgg tatcaggcga atctatgttt
     7561 atcacgcaag ccatttccaa tagtgacgat ggaaaaattg cacttgcgcc ttcaacgcca
     7621 ggtcaggtta ttgccttgga acttggtgca gagcaatatc gactaaatga tggtgccttc
     7681 cttgcccttg acggttctgc ccagtataaa atggaacgcc agagtgttgg gaaagctttc
     7741 tttggtggtc agggtggact ctttgtgatg actacagagg gccatggcac acttttggcg
     7801 aatgcgtttg gttctattaa gaagctaact ttggatggtg gaagtatcac cattgacaat
     7861 gctcatgtgg ttgcttggag tcgtgatttg gactacaata tccatatgga aaatggtttc
     7921 ctccaatcta tcggtacagg tgaaggaatc gttaatacct ttactggtta tggagaaatc
     7981 tatgtacaga gtttgaacat tgagaccttt gctcaggtca ttggcaatca tattgtcggt
     8041 gcaggtggtg atggtggtgg tggaagcaca tcgttgctgg atgcgatttt ttaagaagaa
     8101 aaactctgca attttcaaaa tcatataata aaaataaagt ccctcgcgta atgcaaggga
     8161 cttttcttag tttatttcta ccacttacct gtctaatttt gccacttact gaaatgccct
     8221 tgtaattgga tgtcgaactg gtataataga gctatcaaaa aggagggagc tatgaaagtt
     8281 aggattgaat ttgatgacag cttagatcag gttgaagttg ttatccgaac cagccagctg
     8341 ggaccagaga ttgaacagat tcagcaagct ttgcaacaag ttagtcgtcc ctcgcttgtt
     8401 ttttacaagg ggagcagcga gtattttctt tcattggggg acatactttt ctttgaaacg
     8461 gatggaacca agatttttgc tcatacaggc gatgatgcct acgaggttaa gatgaaactc
     8521 tatgaacttg aggagcattt gcccatctac ttttgtaggg tagctaagtc aaccattgtc
     8581 aatagcaagt tagtctattc gctaaataag tccttctcgg gcaccagtcg gatttccttc
     8641 tataagactc acaaggaagt ccacgtgtcg cggcattatt atcatttatt aaaagaaaag
     8701 ttacaggaaa tgaggtagga agatgaaacg tttattaatt ggagctgcag ttataggact
     8761 ggcggttttg gtcttgttga gggagtcatt gggtttgcat ttggcaatgc ccttttggac
     8821 cactgtctgg tttgtattaa cctttgtgac aggttttcac cgcttggtaa agttggattg
     8881 gcttgccagt atcttttgtt tcggcctagc ttttatagct gccaactctg tctatgaatg
     8941 ggtggagttt gggacttgga acatgtttct gtcgcttgtc ttactctgtc ttggcttgaa
     9001 actaattttt aaaccaagga agcgcagact ggctcatgga gttgtcacag gggtgattgg
     9061 cgataaggga cgcgatacag cttttggttc ctcgactcga tacatccatg aggaaaattt
     9121 tatccatgat agtgtggatg tagcctttgg atctagtaca gtctattttg atcaggcggt
     9181 gattctgggt aataaggcag attttcatat cgatgcggcc ttctcaaata tcacactcta
     9241 tctgcctgct gactggcaag cggttgtaga gttggatagc gccatgtcaa caactaacaa
     9301 ctacgcatct gagccaaaag aaaagattct cttggtgacg ggtgatatgg cattttctac
     9361 attaaatatt tactctatgt aaaagaataa tcgcagagga aggtctatcc aggctcctct
     9421 gtaggacaaa aaatcagaat attctgaaaa ttaatcaaaa gaaagggatt atcatgaaaa
     9481 agattttgaa aaatgctact tacctatggg tactgactgc ggatatgttg tccaattttg
     9541 gcgatgtggt ctattatctg gcattgatga actatgtttt actggtgccc aacagtcgtc
     9601 tggctctggc gatcgtgacc ttctcggaaa tcttccctag ctttatgggg ctctttacgg
     9661 gctatctagc agacaagacg gtcaataaaa tcagcaccat caagctgacc ttactctttc
     9721 gtgtccttct ctacctcatc ctcggattct gcatgggctt tgagccagcc ctctggattg
     9781 tcgtagtggc agctagcttc aatgtctttg cagacttcgc tggcttctat gaaaacggcc
     9841 tctatacacc tctgggatta cgcgtagcgc ccaaagaaga gcgggagcag tactcggcct
     9901 ttcgccagac cgtgaccagc ctcctcaaca tcgcctttca ggccctctct gccctcttgg
     9961 tcggcctcct ctcctaccaa aacctggcct ttctcaacgc cggcaccttt ttagcctccc
    10021 ttctcatcat gcagctgctg acgccagcct ttcgcaaact cctgacggag cagcctttga
    10081 aaatagcgga gcagccgaac cagactgagc caaaaaccaa gggaccaggc attctagctt
    10141 ctttcaagca agcaatcgtg gagctgcgca agatacccga gttccgcctg gtcctgatta
    10201 ccaaccctct tatcaacgcc tgtggagcga ttctctatcc tattctggtc ctgctgatta
    10261 gcgaagaccc aggcctcgtc ttcctcaatg ttgaaacaac ccttgccctg accattctga
    10321 tcttctttat cggacatatt ctgggctcga ccttagtctt tacccttttc aaaaatacca
    10381 gcatggtgac gctggaagtg gcagccactt tctctcttct tggcgttttt gtcggaatgt
    10441 tgcttcatca actgccaatt attttcttct tccttactac aatgggaatt agttctggag
    10501 ctagtggacc taagtttaac gctaagtttg tcaattctat gccagaggag cagttggcga
    10561 ccattggcgg agcggtatca acctatttta tgctaggtca agcctttact cgactgttgg
    10621 tttcgggttt ggtcttaatc ttgactgtca atcagattag cggacttttc ctagctgcaa
    10681 ctggtttgtt agtcctctat gtcttctact ggctggcacg taaccaaaaa acacctcaaa
    10741 atcagtctgt ttagactgat ttttctgttt tcttatgcat atctatgcta taatgttctt
    10801 gattgaaatt ttacaggaga gaaacatgac taaaccaatt cgtgtgcgtt acgcaccaag
    10861 tccaacggga cttttgcata tcggaaatgc ccgtacagca ttgtttaact atctttttgc
    10921 ccgtcatcat ggcggtactt tcctcattcg tatcgaggat acagaccgca agcgccatgt
    10981 ggaagacggc gagcgttctc aacttgaaaa cctgcgttgg ttgggtattg actgggatga
    11041 gagtccagaa acccatgaga actaccgtca gtctgagcgt ttggatattt accaaaagta
    11101 tgttgatcag ctcttggcag aaggcaaggc ctacaagtct tatgtgaccg aagaagagtt
    11161 ggcggcggag cgtgagcgtc aggaagctgc gggcgaaaca cctcgctaca tcaacgaata
    11221 ccttggtatg tctgaggatg aaaaaactgc ctacatcgca gagcgtgagg cggctggcat
    11281 tgtcccaacg gtccgcttgg ctgtcaacga agctggtatc tacaagtgga acgacatagt
    11341 taagggtgag atcgagtttg aaggtggcaa catcggtggt gactgggtta tccagaaacg
    11401 tgacggctac ccaacctaca actttgccgt ggtcattgat gattatctca tgaaaatctc
    11461 gcacgttatc cgtggggatg accacattgc caacacaccc aagcagctca tggtctatga
    11521 agcacttggt tgggaagcgc cagaatttgg tcacatgacg cttattatca attctgaaac
    11581 aggtaaaaag ttgtctaaac gtgatactaa cacccttcag ttcatcgaag attaccgccg
    11641 taaaggttac atgcctgagg ctgtcttcaa ctttatcggt cttttgggtt ggaacccggg
    11701 tggtgaagag gaaatcttct ctcgtgagca atttatccaa ctcttcgatg agaaccgtct
    11761 cagcaagtca cccgctgcct ttgaccagaa gaaaatggac tggatgagca atgagtacat
    11821 caaaaatgct gatttagaaa ctattttcaa ccttgctaag ccattcttgg aagaagcggg
    11881 gcgtttgaca gacaaggcag aaaaattggt ggaactttac aagccacaga tgtcatctgc
    11941 ggatgaaatc gttggtttga cagacctttt cttctctgat ttcccagaat tgactgcgga
    12001 agaaaaagaa gtcatggcag gcgaaacggt tccaactgtt ctcaacgccc tcaaggaaaa
    12061 attggaagcc atgacggacg aagatttcca accagataac atcttcccac aaatcaaggc
    12121 tgttcaaaaa gaaacaggca tcaagggcaa aaacctcttc atgccaatcc gtatcgctgt
    12181 ttcaggcgaa atgcatggac ctgagttgcc aaatactatt tacctgctcg gccgtgaaaa
    12241 atccatccag catattgaca atatgttgaa gagtttgtaa tgaaataatc cccactgtca
    12301 tatggcggtg gggatttgtc atagtttgaa gctataacac ctggattgaa aacgatataa
    12361 ccagtttttg aaaatccatg gtatgataga ataatcacaa gaatttagga gagtttatgg
    12421 aaaatcataa ttttgaaaat caagggacct ttaaccgcga gatgaacagt cgtcatttgc
    12481 agatgttgtc catcggcggg gttatcggga caggattgtt tttgagttca ggctatacca
    12541 ttgcacaggc tggtccattt ggagctgttg cagcctatct tttcggagct gttatggtct
    12601 atttggttat gttttctttg ggtgagcttt cggtagccat gccagtcaca ggttcttttc
    12661 atacctatgc gaccaagttt atcagtcctg gaacaggatt tatggtggcc tggatgtatt
    12721 ggctttgttg ggtagtcgct ctagcttctc agttcgttgg agcagcacag cttatgcaac
    12781 gctggtttcc tagtgtaccg atttggattt ttgcgacgat ttttgcagtt attgtctttg
    12841 ggctaaatac cctttctgtt ggttggtttg ccaaggcgga ggatgcactc tcgtctatca
    12901 aggtctatgc catagcagcc tttattgtgc ttgggacttt agctattttt ggtattttgc
    12961 catttgaggg aaccaatgct gcgccgctct ttactaatat tacagcccaa ggtttacttc
    13021 ctaacggcct agttgggttg atttcagtta tgctgtcggt taactatgcc ttttcaggtg
    13081 tggaaatgat cggaattgcc gctggagaga ctgacaatcc taagaaagcc gtgccacaag
    13141 ccatcaagtc aacaatcggt ctcttggtca tcttcttcgt cttgaccatt gtagtcttgg
    13201 cagccctact tcctatgtca gaagcaggtg tgacagaagc gccattcgta cttgtattgg
    13261 ataaaatcgg ttttccttac gctgcagata ttatgaactt tattatcttg acggctattt
    13321 tatcggcctc tacatcaggg ctatacgctt caagccgtat gctttggtct ttggcaaatg
    13381 aaggcatgat tagcaaggaa ttggtaaaaa ttaataaaca cggtgttcca atgcgtggca
    13441 tgatcttgtc catgattggt gttgtgattg ccttggttgc gtcaatttat gcagaagata
    13501 ctatcttcct tgctctggtt tccattgctg gttttgcagt tgtgattgct tggttggcca
    13561 ttccattggc acaaatcggt ttccgacgtg aatttttgaa gaatcatagc gaagatgaat
    13621 tggaatacaa gacacccttc tcaccaacct tgccgtggat tacggttgtt ttgttggtta
    13681 tttccatcat cggaatcggt tgggatcctt ctcagcgtgc cggtctttac tttggtgtgc
    13741 cattcatgat tggctgctat atttatcact acatccgctt caagaagtgg taaggagaaa
    13801 ctagtatggg tcgttttaaa gaactattag aacaaaagga atacatcatt ttacacggtg
    13861 ctcttgggac ggaattggaa tttcgaggtc atgatgtatc aggtaagctc tggtcagcca
    13921 agtatctttt ggagaatccc cagtatatca aggatatcca caaggattat attcgtgccg
    13981 gagcagactt ggtcacgact tcaacctatc aggcaacctt tgaaggatta gcagaagttg
    14041 gtttgtcaca agcagaggct gaagaactca ttcgcttgac cgttgatttg gccaaggaag
    14101 cgcgtgatga ggtttgggca gaattgtctg aagctgaaaa agtacaacga acctatcctc
    14161 tcatctcagg tgacgtgggt ccctacgcag cctatttggc gaacggtgct gaatatacag
    14221 gcgattatgg caacattagt ctgtcagaat taaaagattt ccaccgtcgc agaattgaac
    14281 tcctcttaga acaggaggct gaactcttag ccttggaaac catcccaaat gttcttgaag
    14341 cacaagcctt agtagagttg ctggcagagg attttccaga ggctgaagcc tatattagtt
    14401 tcacctcaca agacggtcag tcgatttctg acggaacgtc tattgaaaaa atagcagagc
    14461 tggtcaacag cagtgagcag attttggcgg ttggtcttaa ctgtacggct ccctcgctct
    14521 atccagcctt tctcagtcag ttgagagaaa aaacggataa accatttgtc acctatccga
    14581 attctgggga agtctatgat ggagccactc aaacttggaa ggaaaaggca gacgacagcc
    14641 attctcttct ggacaacaca cttgaatggc acgaactggg tgccaaggta gttggaggtt
    14701 gttgccgaac ccgaccagcc gatattgctg acctagttgc aggtttgaaa taaaaggagc
    14761 cccgctgtcc tgtgacggcg gggatttgtc tgttagggga atttagcttt ctaaaaacag
    14821 cctctccaca tagtctttct gccttggaat gactagctct gtttccagga aatctttcaa
    14881 attttcttgt tgcacccaga tataattgct ggtttcgttg gcttggagtt ggatagcaac
    14941 tttgtcccag tcggtttcag cccagtagca gtggaaaatg cactggtcgt catgggcaac
    15001 aaagtgttta tggtggcgta gttggtcagc tgtcagctca atgcctgtct cttcgcggac
    15061 ttcgcgcaaa atggcctgct ctgctatttc tccaaacaaa gccgaacctc ctgctgtcgc
    15121 ttcataatag tcagggtagg agggtttggt gctgtcgcgt ttcatgaaga gggtgctgcc
    15181 gtcgtggtgg cggatgatgc actcgacgac taggtggtag aggccgtcgg gaatggattc
    15241 tccgcgtgtg agggtgtggt cggtcaagtg accgtcggct gtgtaggcat tccagatttc
    15301 catagcttgc tccttttcta tccttctatt atagcatagg aagttttcct gtgagcttgt
    15361 acggacaagt gtgtggtata atgggcagac gaaagaaaag gagaaattta tgcaacctat
    15421 tattcctcat ctctggtatg atacagaggc aaaagaagcg gtggcttttt atgtggacct
    15481 ctttggtggc aatgttgact ggacctacac gattacggat acgccttctg gtgattcgga
    15541 tttgattcag tttcaactgg gggatatgac cttggcggct attagtgcgg gtccatactt
    15601 tacgctcaat gagtccatgt cccttatggt caatgtagcc gacaaggatg aagtgacacg
    15661 tttgtaccaa gccttgtcag aaggcggtcg tattctcatg cctttgggag aatatccttt
    15721 cagcccttac tatgtctggt tggaagaccg ctttggtctg tcttggcaac tgtcttatgc
    15781 accggacttg gacaagcctt atcagtttga catctgcctg ctcttctcgc aggaacaggt
    15841 cggtttggcc cagcctatgt tggactacta caaggacaag ctccctcagg ctagtgtcgg
    15901 tcaactttcc tactacggtg aaggggaggc tgctgttgag gctgccaaac tgaattatgc
    15961 ggaacttctt gtcgctggac agaaaatgat tgttatggac cacggctacg gtggcgtggc
    16021 ttctttcaac gaagccttct cattcatggt ctatgtagac agtcaggaag aagcggagag
    16081 ctggtatgaa aaagtgtcgg cagttccaga agcggagatt tgcggttggg ccaaggacca
    16141 gtttgggatt tcttggcaga tcgtgccgcg tattttgatg gaagcatacg atacggctaa
    16201 cccagaaaag gtcaaggcag tcaatgcggc tgtgatgacc atgaaacgtt tggacattgc
    16261 ggctattcaa gcattgctaa actagcagat gataacggag actgttctgc agtttccgtt
    16321 tttgggttga ggaaaggttg atttacagga attttgatat aatggaaaaa agtgtacgaa
    16381 aggaatgtgt atgaaagcaa cagaacgacg taagaaaatc ctatcccttt tacgagaaag
    16441 cccctatccc cttgcagcta attatctggc gaaagaattt ggagtgagtc gacaagtaat
    16501 tgttggagat gtagccttgc ttcgtgcgga gggagaagct gtcttggcaa ctccgagagg
    16561 gtacttactc caatcttctt tgccatctac tgaaggagcc tacattcgaa agatagcttg
    16621 tcaacatggt ccagaagagg tagaaaaaga attgacaatc ttgctagagg gtggagctca
    16681 aatactagat gttgaaattg agcatcccat ttacggctta ttatcaggca agctgaatat
    16741 tgcaagttta gaagataggg atcatttttt ggatgcctta ggtcaatacc aaggtgtgtt
    16801 actgagtaat ttaacagaag gagttcatac acatacagtc tctttcccat ctgtgcaagc
    16861 ctataatgaa ctttcagcag ctttaaaaca tgcaggtatt ttactagaaa attaataaat
    16921 cttacaggcg tcttgacacc tgtaaggttt tgttttataa tcaaaccaat agaaagagag
    16981 gtgcctaatg tcccaattaa cactatcatc taaaaattca gttaagcagc tatcaattag
    17041 tgcaatttta accgcatttg ccattttaat acctttaatg atgccgatta aaatcattat
    17101 tggcccagca tcctatacac ttgctagtca cattcctttg tttatagcca tgtttatttc
    17161 accagctact gctatttttg ttgctttagg ttctagttta ggctttttcc tcgccggttt
    17221 tccaatcgtt attgtatttc gggcgcttac gcacctgttc ttccttacct taggtgcggt
    17281 cttggtcaag cgttttccga ttctcatgga ttctaagcgc tttttactat taggaattgg
    17341 gcttaatctc ctgcatggtc taggagaata tattgtggtg atggtgctta cttcggggca
    17401 acaaacttct gctacctact ggataacgat gcttggcttg gtgggtgttg gctcggctat
    17461 tcatggattg cttgatttta gtttagctta ttatttctgg aaaattttaa aagaacggaa
    17521 aatttatcaa ccataatcag ttatgatgag gaatatattt tagaagctgg agaatattct
    17581 ctagcttttt ttggaaattt ttctggaaat gtacgatatt tattcatttt ttaagaaaat
    17641 ttgcataaat atgttgcaaa aaagtataaa tatacactat aatagtcact aagttttatt
    17701 tgctaatata tatagaaatg agaaagttta tgacaaaaga aaaattaatt ttggcctatt
    17761 ctggtggact tgatacttca gttgcgattg cttggttgaa gaaagactat gatgtcattg
    17821 cggtttgtat ggatgttggt gaagggaaaa atctcgaatt tattcatgac aaggcccttt
    17881 ccatcggtgc aattgaatcg catgttttgg atgtgaaaga agaatttgct caagaatacg
    17941 ttttgcctgc cctacaagcc catgcctact atgagcaaaa atatccgctg gtatcggctc
    18001 tcagccgtcc cttgatttcc aaaaagttgg tggaaatggc tcataagaca ggagcaacca
    18061 ctatcgccca cggctgtact ggtaagggaa atgaccaggt gcggtttgag gtagccattg
    18121 cagccctgga tccaagcttg aaagtcgtgg ctcctgtccg tgaatggaag tgggcgcgtg
    18181 aagaagaaat catcttcgcc aaggaaaatg gtgttccagt tcctgccgat ctggacagtc
    18241 cttactcagt cgaccaaaac ctctggggtc gtgccaatga gtgtggtgtc ttggaaaatc
    18301 catggaatga agcgccagaa gatacttttg gcatcactac ttctccagaa aatgcaccag
    18361 atactcccga gtatgtcgat attgagttta aagcaggtat tcctgttgct gtaaatggtg
    18421 aaaagttaag tcttgctaat ctcattcaaa gactcaatgt cattgctggt aaacatggtg
    18481 tgggtcggat tgaccacgtg gaaaatcgtt tagtcggaat caagtcacgg gaaatttacg
    18541 agtgcccagg agctattacc cttctgacag cccacaagga aattgaagat ttgaccctgg
    18601 tacgggaagt atcgcatttc aaaccgattg tttcaaatga actctctaac ttgatttaca
    18661 atggtttgtg gttcaatcca gcaacagatg ccttgaaggc ctatcttgct cagacccagg
    18721 cagttgttaa tggcaccgca aaagtgaaat tgtataaggg gtcagccaaa gtagttgctc
    18781 ggaaatctcc aaattccctt tatgacgaag atttggcaac ctataccagt gcagatacct
    18841 ttgatcaaga tgcggcagtc ggtttcatca agctttgggg attgccaacc aaggtcaatg
    18901 cggaaattca taaaaagagc tagaaagtag gagcctatgg aagcaaagaa attatgggga
    18961 ggtcgctttg aagccagtct tgaggaatgg gttgaagaat tcggagcctc cattcgcttt
    19021 gaccaaaaat tggccaagta tgatattcaa ggctcactgg cccatgtcaa gatgctgggg
    19081 caaactagga ttatctctca agctgaggct caggtcattc aagctggtct ggaagaattg
    19141 ctagaggagt atgaggctgg caagctggta tttgatattc gaaacgaaga cattcacatg
    19201 aatattgaaa gtctattgac ggagaaaata ggctcagttg caggcaaact ccatacagct
    19261 cgttctcgta acgaccaagt ggctacggat atgcaccttt atttgaagga tacactcttt
    19321 caagttgtag acaaattgac caacctacgt cagattttag tagaccttgc acaggagcat
    19381 gtggaaacaa tcatgcccgg ctatacccac ttgcaacatg cccagcccat tagttttgct
    19441 cagcacttgt tagcctatta caacatgttc agccgagaca gtgagcgctt tgcattcaac
    19501 atgcagcata caaatgtatc cccacttggt gcggcggcct tggcagggac gacctttccg
    19561 attgaccgtc agatgacgtc tgatttgatg ggatttgcca agccctatag taattctctt
    19621 gatgctgtgt ctgaccgtga ttttatcttg gaatttctgt caaatgccag tatcctcatg
    19681 atgcacatgt cgcgtttgtg tgaagaaatc attaactggt gttcatatga ataccaattt
    19741 gtcaccctat ccgatacctt ttcaacaggt tcttccatca tgcctcagaa gaaaaatcca
    19801 gatatggctg agctgattcg ggggaaaaca ggtagagttt atgggaactt agttggccta
    19861 ctgacagtca tgaaatccct gcctttaacc tataataaag acttacagga agacaaggaa
    19921 ggcatgtttg acacggcaga aacagttttg atttcaattg atattttggc gggtatgctg
    19981 aaaacgatga cggttcataa ggaaaggatg gctcaatcga cagagaagga cttttcaaat
    20041 gctacagagt tggctgatta tttggctagt aaaggtctgc ccttccgcca agcgcatgag
    20101 attgttggaa aactggtctt ggagtgtagc aaggcaggac actatctcca ggatgtatca
    20161 tttgagacct atcaggctat ttcgcctctt attcaagcag atatttatga tgccttgtcc
    20221 tccaaagttg ctgttagtcg tagaaattcc cttggcggga caggttttga atcgattgca
    20281 gaccagttga aaagtgccaa agaggaaatt cagaacgcaa aaagcctata aacggtatgt
    20341 ttattggctt ttttgaattt tgtggtataa tagaagtaat tttgaaagat ggagtggcag
    20401 tttgaaaaaa agctatcgtg tcaagcgtga acgagatttt aatgacattt ttacaaaagg
    20461 aaacaatgtc gccaatcgga ggtttgttgt ctaccgatta cctaaagagc aaaagcattt
    20521 ccgagtaggt ttatctgtca gcaaaaaatt gggaaacgct gtcatgcgaa ataagattaa
    20581 gcgcaggatt cgtcacatct taattgaatg ccaacatcaa ctggtagcag atgactttgt
    20641 tatcattgct cgaaaaggtg tagaggaatt gtcctatcaa gaaatgaagc aaaacctcat
    20701 ccatgttttg aaactagcta aactatacca ggaaggtgtt gtgattgaaa aagaaagtta
    20761 aatgggcagg tctactggta gcatctctaa ttgttttaac agcctgcgga acagggccag
    20821 tgaccagtca atctacagat gcgtgggata gattaattta ctggtttgcc agcattattc
    20881 agttcctatc tatcaacggt caaattggaa tcggtattat actttttacc attttaattc
    20941 gaacccttct gttgccgttg ttccaaatac agatgaattc ctcacggaag atgcaggagc
    21001 ttcaacctca gctgaaaaag ttgcaagcgg agtatccagg aacggatatg gaaagtcgcc
    21061 agcagcttta tgaagcaacg caagctctct acaaagagaa tggcgtcagc atgagagcgt
    21121 ccatgattcc gctctttatt caaatgccaa tccttttggc cctctttcaa gctctgacac
    21181 gtgttgaagc cttgaaagta ggtcacttcc tttggttaaa tcttggggag ccggatccgt
    21241 tctttatttt gccgattcta gctgcagtgt ttacattcct cagctcatgg ttgaccaata
    21301 aatcagcaat tgagaagaat atggctatga caattatgac ctatgtcatg cccgtgatga
    21361 tctttttctt tgctgtggca gctgctagtg gggtggcttt gtattggaca gtgtcaaatg
    21421 cctatcaggt tgctcaaacc ttggtgttca ataatccgtt taaaataata gcagagcgtc
    21481 aagcgaaaat tgatgctgaa aaagagcgtc aggcaaaaat ccgacgggca cagaaaaaag
    21541 cacagaaaaa gaaataggaa aactaggaga gagaagatga aatttacagg agcaagtgtt
    21601 gaagaggcca tccagaatgg cttggtagag ctgaatattc ctcgaaaaaa agcacatatt
    21661 actgtggttg cgcgtgagaa aaaaggtttc cttggtttcg gtaaaaagcc agcgattgtg
    21721 gatattgatg tcatcaatga aacaacggtt gttaaggcta atcagaaagc agttcgtggc
    21781 gttccaagtg aaattaatga cctcaatgaa ccagtaaaaa gcgtttcaga ggctacgatt
    21841 gacctaggaa aagttgttgc agcggtgaaa gaatttgaaa agtctggtca aacgcttgat
    21901 gatgatatta aagcgcagat cttgaaaaat gaaaaagaag cgacaacgat tttggaagaa
    21961 acaggtcgga ttgaaattct ttcagaggat ttactaacta ctacagatgc aacaacatct
    22021 gctaaggaag acgtaaatca agaagtcatc tcagaaaatc aagcagataa ttttgctgat
    22081 ttagatatta agattgagcc ccagtatgat attgaacaag ttgtttcgga agtgacagct
    22141 tatgtacaag aaattctgga tgatatggat gttgaggcgc gtattgatac aagtcataat
    22201 cgccgtacaa tcaatattca agtggatacc aatgaaccag gtcgtgttat cggttatcac
    22261 ggaaaagttt tgaaagcctt gcaacttttg gctcagaact tcttatacaa ccgttatgag
    22321 cgtaatttct atatcacaat caatgtgaat gattatgtag aacaccgcgc agaggttctt
    22381 caaggctacg cacaaaaatt ggcagaacgt gttttggcag agcaggaagc ctaccataca
    22441 gatccgatgt caagtagcga acgtaaaatt atccaccgca ttatctctaa aatggatggt
    22501 ttgacaagtt attcagaagg tagcgagccg aaccgatatg tcgttgtaga tattgaagga
    22561 aatcatgatt aaaaagaggc tagtcctctt ttttcaatga ttttctgatt ctttcctaaa
    22621 agtatggcag aatagcttga caaacgaaca gaatttatat aaaatagttt ggtatgttta
    22681 gtaactgatc aaaactagcc ggctaaacga atacaagaat ctaagaggag gtattcatcg
    22741 tgaaacgtac ttttcaacca agtaaaatcc gtcgcgcgcg taaacacggt ttccgtagcc
    22801 gtatggcaac taaaaacggc cgtcgcgtgt tagctgctcg tcgccgtaag ggacgtaaag
    22861 ttcttacagt agcataagaa gatgaaaaga gaagccagca gaaactcgag tctgctggtt
    22921 tttttcttct cataagaatc ttctgaaata tgttacaata gtaggaaaga aagtgatgga
    22981 acgatgatac aaatttttga tacccatacc cacctcaacg tagagcagtt tgacggtcgg
    23041 gtccaagaag aattagactt tgccaaggag atgggggtca ccctccacaa tgtggtcggt
    23101 tttgaccgtg caaccattga caaggctatg gagcttgctg accagcaccc tgaaatttat
    23161 ctgacactgg gctggcatcc cacagaggct ggcacttatg acgaggaagt ggaaaactat
    23221 ctgctcaaag ccctccagca tcccaaggtc attgccctgg gagagattgg actggattac
    23281 tactggatga cggcggataa ggaaatccag gctcgtgttt tcaagcgaca gatggagctg
    23341 gccaagcagt tggatttgcc ctttgtggtt catactcgcg atgctttgga agatacttac
    23401 cagatcatca aggaagtcgg cgtcggtccg cgtggaggca tcatgcattc cttctctggc
    23461 actctggagg aggctcaagc tttcatggac ctgggcatgc acatctcctt ctcgggagtg
    23521 gtgaccttca aaaaagccgt tgaacttcag gaagcggcgc aagcattgcc cttagaaaaa
    23581 atcctggtcg aaacggacgc accctacctg gcgcctgttc ccaagcgtgg tcgggaaaat
    23641 cgcaccggct acaccagata tgtggtggat atgctggccc agcttcgcaa ccagtcggtc
    23701 gaagaagtgg cggctgcgac ctacgagaat gcaaggagtt tgttcagaat tgactcagaa
    23761 aattaagata caagaagtcc tcgttgttga aggcaaggac gacacggcaa acttgaagcg
    23821 gttttacgag gtggatacct acgaaaccag aggctctgcc atatcagacg atgacttgga
    23881 acgcatcgag aaactccatg acctgcgtgg cgtgattatc tttactgacc cagactacaa
    23941 tggcgagcgg attcgaaaaa tcattataca ggccattccc acggtcaaac acgctttttt
    24001 acagcgggac gaggctgccc ccaagtccaa aacaaaaggg cggtccttgg gcattgagca
    24061 cgccagcttt gaagacttgg aaaaggccct agcaggcgta cgtggtcatt acgatgatga
    24121 aaataacttt gatattagcc agaagaccct gattcggcta gggttgctta tgggtggcga
    24181 cagtcgcaag cggagggagt atctgggaga gaagctccgc atcggctact gcaacggcaa
    24241 acaactcctc aaacgattgg aattgtttgg gataagtttg gcggaggttg aggaggctat
    24301 ggagagctat catggatagg gtctacgctg ttaagtgctt ggttaaaaac gagtttgaac
    24361 cttcttatga aaattattca tcttatgaag aagtgaccta cttgctgccg gctgatgtcc
    24421 ttgtttggga ggatgagcag gttgataaga acaaactagc agactatttg cttggtttag
    24481 ttgaagatgg ctatgtcaat gcggatggta tttggaagca gagccgtttg tttcatattg
    24541 ccggtgtgca agaaatggac gacagggtag agtttgatgg actagccgtg gaagtctatc
    24601 gctggtttta caattttgaa cgtccagtta ctgaggaaga atttttgaat ctctattatt
    24661 ttgatgattt ggggagatag gcaatctaga gcggaaatat tactatttct gcttttttga
    24721 aaattgctag cggtgtctat ttgtgttaaa atatagaaaa ctaggaggtg gactagattg
    24781 ataactataa ataaagatgc ccaagtaaat tttaaaactg attccagact tttagaaaaa
    24841 gccaaggaag tatttgctat gaaccagctg gatttgactg ctggttttaa cctcttcttg
    24901 caaaatatcg ctgtaaaaaa tgagttgcca attctgacag aagaagagtt ggaaagagaa
    24961 gagttgtttt tacagttaca gaaggaaatc caggaaaacc aacaggcgat tgaggcaggt
    25021 cacgggatca gcctagaaag tgtcaaagag aagtatggaa tttgagtctt attcagtgat
    25081 acttgctcca gcagtggaga aggaattggc agttatttac gcctattttt cggaacagtt
    25141 ctcagaagaa attgccaaaa gacgaattgg gatgattgtc gaagcattag agagtttgca
    25201 aatttttcct gaacgtggtt ttaacgccga taaccgtttt ggtaagcaga tagacccgcc
    25261 tcatctaacc cgaggctatg tcgttggaaa agactacatc gccctctatc gcgtagtgaa
    25321 aaatgaagtt cgagttggtc atctttttgc gaccaagagt gattatgtga agttgttgaa
    25381 gtgagagagc atgagtagga cagagcaagt catcctaacc aatatgtgca tgattacaga
    25441 cggtcagcag gtattagttc aggataggaa ttcaaagaaa tggcctggtg tgactttccc
    25501 tgggggccat gtcgagccaa atgagtcaat tatttcctcc gtcattcgtg aaatcaagga
    25561 agaaacgggc ttgacggtat ccaatctcga actctgtggc attcaaaact ggacggatcc
    25621 tactgaccat tatcgctatc tggtattttg ctacaaaacc agttattttt caggttttat
    25681 ccaatcttct gatgagggcg aggtcttctg gattgaccgt gcagaattga agaatctcca
    25741 acttgctgac ggttttgaaa ccatgttgga aatctttgaa cagccgcagc tgacggagaa
    25801 tttttactgg tttgaagacg gcgaatggaa ggtggagaat cgttaaagag ttgtacaata
    25861 agtttgacaa ctcttttttt ctatgctata gtaagcctag aaatgatgag aggtattgct
    25921 tatggaagct attgtatatt cccattttcg aaatcactta aaggactata tgaaaaaggt
    25981 caatgacgag tttgaacctt tggtcgtggt taataaaaat ccagaggaag atattgttgt
    26041 actctcaaag agtgagtggg atagtttaca agaaaccctc gctgttgctc ggaacactta
    26101 tctgtctcaa aaagtcctac gtggtatggc taaagtcaaa acgggacaaa cccaagaacg
    26161 aaacctgata gaggcggact aacatgggaa tccattttac agacgacgcc tgggaagact
    26221 atctttattg gcagggtcag gataagaaaa cactgaagag aatcaataag attatccagg
    26281 atatgcagcg acatcctttt gaaggcattg ccaaaccaga acctttgaag tatgattatc
    26341 aaggtgcctg gtctcggaga attgatgcgg agaatcggtt gatttatatg gtggaagctg
    26401 atcggttgtg catcctgtcg ctaaaggatc attataggtg agggggatta acaaatgaaa
    26461 aaagtcgtcc tccttcgagg tgttacccct gttggcaaga ataaaattcc caagatgtct
    26521 tacttggcgg aaattttgac ggaagctggt ttaacttctg tccaaaccta tattcaaagc
    26581 ggaaatgttg tttgtgaaac agatatatta gatgaagaac tcagtcggct tatccatcaa
    26641 accattaaag aaaaaatagg tgcagagtta gcgatcattg tcaaacatca gatggagtta
    26701 acacaagcag ttgctgaaaa ttcttttggt gagggctatg atccttctcg tgttcatttg
    26761 gtctttacca atgatgagat aaatggtgaa aaattaaaca aattattgca ccaagacttt
    26821 ggcgatgagg agttgcgtct gggaagtcaa tgtctataca tgtatcttcc gagagatgct
    26881 cgaaagaaaa aactaaatac caattattta gaaaaacagc tggacattac agcgacgatg
    26941 agaaaactaa gtgttatttc acgattgagt gaaatggcga aataaaaaac aagaaagaac
    27001 acacatgaga attgcagaca aaaacgttac tcgtgccgtc cttgaacgcc acgggtttac
    27061 ctttaagaaa tccttcggtc aaaatttttt gactgatacc aatattttac agaagattgt
    27121 ggacacggca gagattgacc gaaatgtcaa tgtcatcgag attggtcctg gaatcggggc
    27181 cttgaccgag tttttggcgg agaatgccgc tgaggtcttg gcttttgaga ttgacgaccg
    27241 cctgattccg attttggcgg acaccttggg tcgctttgac aatgtgaccg tggtcaacca
    27301 agacatcctc aagaccgacc tgcagaccca gattcagaac tttaagaacc ctgatttgcc
    27361 catcaaggtc gtggccaacc tgccctacta catcaccacc tctatcctca tgcacctgat
    27421 tgagagcaag attcccttca gcgagttcgt ggtcatgatg cagcgggagg tggccgaccg
    27481 catttctgct gagccaaaca ccaaggctta cggaagcctg tccattgcgg tccagtacta
    27541 catgactgcc aaggtggcct ttatcgtgcc tcgcaccgtc tttgtgcctg caccaaacgt
    27601 ggactccgcc attctcaaaa tggtccgccg cgagcaacct ctggtgagcg tcaaagacga
    27661 agattttttc ttccgagtgt ccaaggccag ctttgtgcat cgccgcaaga ccctgtggaa
    27721 caacctgacc aaccatttcg gcaaatccga agaagtcaag gacaagctga cgcaggcact
    27781 tggcatggca gagctggaag ccagtgttcg tggcgaagca ctttccatgg ctgacttcgc
    27841 acgtttgtct gacagtcttc aggaagttgg tttataagca agtattgatt gcggagaaat
    27901 ctgcaatcaa tatttatttt aatggaaaat tgttttcctg tttgccttgt tcgttgacag
    27961 tggggggaaa gcttgttata ctgggagttg ataaatttta aggaattatt gtctgcaaat
    28021 gagcagaata gtaagaaccc gtattcacag ttcagcactt ctacttaagg atagttttta
    28081 agctagtcat cgttagtttt ttcaaagtac agtcagtatt ctctcaataa aactgccttg
    28141 attagcgaaa aactatctct tattgataat cacttcactt ctgagtacag gttcttacaa
    28201 aaacaagaga ggggttccct ctttttttat gaaggtatct tatgttaaaa aaattactga
    28261 aaaagcatcc agatattgtt gcagtaactg tattttttct tttttcgctc acccttctat
    28321 tgccacagat tttgacaaaa gcagtggtga caggagacga tattgttttt cattataatc
    28381 gtttttatga tacagctata caaattaagt caggagattt ttcttatata atgagcttgc
    28441 atggctatca gcaatctgga aggattgtca atgctctata tggtccatat ctagcctatt
    28501 tgcaaggagc cttgctgttg ttggccggaa cttggtatcg ataccaacta ctgtctaatc
    28561 ttcttttagg agttttgagt gccacttcgc tttattttct aatgcgagaa gtgaaagtac
    28621 tctattctct atctgttggg ttatccatgt ttttcgcgac tacctactct gttcaatact
    28681 ggtgggtagc tcaaggattt tcaagttggg gagtggcctt atttccgctt tgtttgattc
    28741 cagcagttcg attcctaaaa actggtaaag ttcctatttt tctgatggca ggagctgtag
    28801 ggttaatgtt gcagatacac atgctgtcgg ctctgtttct catcttagcc tatgcaattc
    28861 ttttttcaat tggttggtta aaatcgcaag acaaatggaa cgtaatgaaa gatgtactgt
    28921 tttcggttgg agtttttctg attttaactg taaatatctg gttaccctta ttatatgtaa
    28981 atgcaacaaa tgaattagca gcaccattta taaacaaaaa gtttattcag tcaacagtta
    29041 cctggtctaa ggcttatttc ttatactttc catactctct accaatcatt tttgcaacct
    29101 ctctttattt tatgctgaaa aaatggaaga agcaatcggt gatattgagg ggtctgacag
    29161 taacttttct ggtatttttt attttttcaa caaatctttt tccgtggcaa ctatttgctg
    29221 gtaaaggtat tggattagtg gatttaatcc aatttccctt tagattcttt ttgtatgcta
    29281 atgctttact tctgacgatt gttggtcttc aattaacaga ttacgaagta cgtaaaaagt
    29341 tgtttttggg gttgacaatc ttatctacca taattggtgt tggttttact tgggatcaat
    29401 ataatcaagc agtcaatgac cagtacaaca aagcagaatt cttacaagat atgcttcata
    29461 ctactctata cggaacaacg gaagaattac gtgcatcctt gcattcaaaa aatttaggtg
    29521 agtttgttca actggctcag aaatcaactc ccgactatgt gccggtgtta tctgaaaaag
    29581 aagagaatgt tcgtgcggta aatgaggcta aatctcgtta tgatcgttac cgtgaccaga
    29641 ttattttacc taaccagcaa tttaataagc aagtttttgg ggatagctta aaaataagtt
    29701 ggtcggcaaa tcaatcagag gaaatccaaa taccgattgt tatttaccga gatagtgaat
    29761 tgacattgaa tggaaagagg ttagggaaga tggattatta tctttccact attggtgtgc
    29821 caacggttac cagccaaaaa gggaagaaca ccctaatcct ctcctataag caacaatggt
    29881 ggttattgcc agttatcttt atcagtttga ctggctggat actttggtcg atttattata
    29941 cctttatcta ccgaaaatca aatatttcct aagagagaaa tgctatgaaa caaatcaaac
    30001 tcaaggcaac caagcaattt attctggtca tggtaatgac cgtcttgctg gctatggggc
    30061 gagccctttt actgagtgat gtatcttttc cactctggtt tattcccttg cccttgattg
    30121 cctatcttat ttttacattt tatgtattgg tcttgcttga taaatatgag aaatttataa
    30181 agaccaaaac ctttgccaag tatgtcggct attttctagg ttttctatat cttatcaacc
    30241 tggtctatcg gctcaatgcc aagaagtatc aaccctggaa tattttccgg aataatctct
    30301 ttcaatttga gcttctattg atgttggctc ttcctgtatt gttggcattt ttatggcgga
    30361 agaagacggg aattcgagaa aaattaagcc agtggtcagc caatcacttg gtaccagatg
    30421 gctatttgct cttgaccagc ttactttctc tcagtccact agctatatct tattggaaag
    30481 atagccatta tgagagtttg gttgagaaag gttcttacat agagtttttc agccagacac
    30541 ccttgtttgc acctatccat tttataggga cctacatttt tcttcgctat cttcataagg
    30601 catttgtaga gtttaaggcc aatcgaacca atgtctacag catgctcttt atcagtttgg
    30661 cactggctac gctatcgcat attggttatc aggcttctat ggctggagcg actggttctt
    30721 atttcacacg tcatctcttt ccaggggcta ttgtcttcca gattgcctgc ctctttttcc
    30781 tcaatgtcat cattagccta gttatcaacc gccaaatctt atctgttgcc gtgattgcta
    30841 gtctaaacgt cattttggtt acggccaatt ttctcaaatt ccgctaccgt tcggagccat
    30901 tgacccccaa tgatttcaaa tgggtcggga acttggggat gattctcagc tttatcagtc
    30961 tacgtgttgt cttggtatcg ctcgtcttta tagtcctcct tgtgtttatc taccgacgta
    31021 ttcacaagaa gtacttccaa ggaaggattg tcgcttctat ctggaaaagg ctggcaggaa
    31081 tttcagtcat cgtatccttg attttaggaa tgggctgggc aattcgcaat gaaaaagacc
    31141 ataagattgc tggctggatt cctattcttt ctcaggttaa taactggcgg aatgtagatt
    31201 ggaagggcta cgcctttgtg gctcgttatc gcactctttc attcctctgg ttgcagcaac
    31261 tcagcaagac cagtatggaa atgcctgaga attactctga gaagaccatg aaggccattg
    31321 tgaagaagta taccgccttg gctgaggaaa tcaatgcaga acggacaggt caattgactg
    31381 accagacggt tatctacatt cttagtgaga gtttggctga cccgcgtcgg attccaggtg
    31441 taacccttag tcaaaatgtc cttccaaata ttgagtacat catgagccag actaccagtg
    31501 gcttgatgaa gagtgaccac tatggtggtg gtacggctaa tatcgaattt caggtctata
    31561 gtggtctgcc cttctacaat tacagctcat ccatttcttc agtctatctg gatgtggcgc
    31621 caaatatgaa gaagttgcca agtatcagtg acctctatcc agcagataat cgtattgcca
    31681 tccatcctta ctacgatacc agttacaacc gaaattctat ctataagcag ctggggattg
    31741 agcaattcta cactctcaat agtgccaagt atcctcttac tgtgacggct gaggattatc
    31801 aggggaattt tgtcagtgac aagaagacct atgacttgat tttggatcag gtacgttctg
    31861 ccgataccag ctttgtgtcg gctattacca tgcagaacca tgttcagtgg aattctctag
    31921 agcctgcagg tataatagca tcgggtgagg gcttcacggc tgaggaaaat gaaaacttga
    31981 ccagctatgt tcgcctccta tcctttacgg atcaggcaac aagggatttt ctagaccagc
    32041 ttaagacctt ggataagaaa gtgacagttg ttttttacgg ggaccatttg ccaggtttgt
    32101 atccagagtc agctttcgtg acggacccaa gtgcgcagta taagacagat tatttcgttt
    32161 ggagcaattt tgatacagcg aaatacaatt atgagctagt taactctagc gacatgaatg
    32221 cactgatgct ggagacgacc aataacaagg tcagtcctta ctatgccctc ttgacagaag
    32281 tacttcataa ggaccgagta ggacaggctg agcgagatgc gaaagttgca gaagaactca
    32341 aactggtcca atatgaccta tctacaggaa aaggatacct tttgaaatac aaagattttt
    32401 tcaaagtagc gactgaaacg acagaataaa atcacgacca agtcagatag ctggcttggt
    32461 ttttctttat gtgaaaatgg acacaaatat gggaaggagt ggtataataa aggtgtttat
    32521 acacttcaaa aatcaaaatt atccgttgtc aagagtcttg atgaatggaa aacttttcag
    32581 cctgttacct taaaataaga aagtaacagt gttctatcgt cggcttgaag acgcaaacat
    32641 tgttttgtat tttccacctt caactatctg gaagatagtt gaaggtggtc tactt
//
LOCUS       DBNFCO010000013        32044 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.013, whole genome shotgun sequence.
ACCESSION   DBNFCO010000013 DBNFCO010000000
VERSION     DBNFCO010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 32044)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32044)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32044
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.013"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            83..2068
                     /locus_tag="AC1PIV_000538"
     CDS             83..2068
                     /locus_tag="AC1PIV_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012774933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HIP6611586.1"
                     /translation="MKKVFTYLSTFSVCLFCIWLVSLQLDSLIYHYYPSVSILSRGEE
                     VTYEEVSDALTNLAEKENSLIAKTITETDDSGRTTTSYDVFGKGELPQGLVKADRLVA
                     SQANLAENYYVVKGNLDIKVVENVLQSLGLVDSYIYRPTLLNSLSLFLGRGAPSLGLI
                     IFILTNLALTVVGQIVYLRSAGIEMLSGVRSWQIASRFLRVDGRDIALATGGALVFGL
                     IAILILGWPMVYYRFVAIGIAFYACLLFFLSLSTSIGFMIALNISQLQKLIKGALPLK
                     AIFAILLVGQCLAVCIISIGASRTLTYVGVLHTLTIGEKAWQERQDVFSLSLNREAFI
                     ADEAMAQQQRMAWSHVILESYAKNNVMLVQHHLRHNTIKEHTIIESSKEIPLERVLYV
                     TPNYIQSEGGLYDFNQLEEIKQLGKGEIALLLPKSLQNDASVYQAYFEDMVGKLLADG
                     EGSISLHSNVYYISDEKRWFIYNHTPINYEQFLQAPLIVVLSPESFEETSYFWENALP
                     DFVFFKDKEMLEQLLDKYNLQNTIGSLLSSKQHYNTLRKNVQLEILMTLSPTILGIFT
                     SILLFNTMNLLYFETFKREIAIKRIAGMGFIELHGSYLGEQVGSALIGMGLAMFMTKS
                     VIVSLGVVVALLINSWMLLNNQAKREEKIQLSVLNGR"
     gene            2088..4073
                     /locus_tag="AC1PIV_000539"
     CDS             2088..4073
                     /locus_tag="AC1PIV_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012774934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HIP6611587.1"
                     /translation="MKGKFVLVSTIILAVFMIWLGVSQKETMLVHYYPSVTTLSVSED
                     VTYSDVRQRLEDYSQQTDSVIARRVIEPSKSGGRTFSYDNFSQSPLPRGLEEFQASEK
                     VESALLTKYFIFQGKATVEELRSLLVSLGLDEVQIRKPSTIATLLVFLTQGGQFLAVL
                     VFLITYMALVVIANVRQLRTAGIRLIAGDSRWHLFLLSLQENAKEIALTIPFAVLPAV
                     GLAYLVGLDGYSVYYLVAALVGYHFLLGLIVLFFAATFTLAIRTYHFLPLLKGKMPLQ
                     GILTIMVMGQMLALLVVSFGMAQTVYYSGIWQEYQAGAQQWENEGDYYSLAWNISADG
                     RSGLNSPENWYPLLRQALEEDGALFVKSNLNAYLMGFQLEDGTRLDSYHPAGNTLYVS
                     PNYLQIQDVDLAEGEVALPLQEGEFQLLLPEKLRPESDAYLHLYQDYINRMVRPANQA
                     RSATIKGKVAYLKNGQKQFIYNHRSGQHVQYLTDPILVVLAPSSLGKESADFWLNEVD
                     SSMLFKNRDKLLRELKARNLFQFVNEVRSSSSLFTELLDRIRIETISTSMGAILGIVT
                     SIVLFNTMNLLYFEEFKREIVIKEIAGMGFLGIHKKYLTLQLLSLLLALGASMVVTGH
                     IFISSISFALFMVNALCLLRWQARKEGAWNVRILKGA"
     gene            4075..4707
                     /locus_tag="AC1PIV_000540"
     CDS             4075..4707
                     /locus_tag="AC1PIV_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002941042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIP6611588.1"
                     /translation="MFSVQSIQKKFGKRSLFSDVTLDLQAGKVYALIGASGSGKTTLL
                     NILAKLESYDAGDILYKGKDLKKLKPHLFFREELGYLFQNFGLLESQTIKENLDLGLI
                     SQKLSKDERKSRQEAALDAVGLSYLDLSQPIYELSGGEAQRVALAKVILKNPPLILAD
                     EPTAALDPKSSQEIMDILLSLKSPDRLIVIATHNPLIWERADLIIKMEDL"
     regulatory      4920..5024
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            5131..6465
                     /locus_tag="AC1PIV_000541"
     CDS             5131..6465
                     /locus_tag="AC1PIV_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009909199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/glycine:cation symporter family protein"
                     /protein_id="HIP6611589.1"
                     /translation="MLELFKAINNLVWGPPLLLLLVGTGVYFTLRLGVFQIGKLPTAF
                     RLIFSSDQSGQGDVSSFAALCTALAATVGTGNIVGVATAITTGGPGALFWMWVAAFFG
                     MATKYAEGFLAIKYRTKDANGQAAGGPMHYITLGMGQKWKPLAVFFAISGVLVALLGI
                     GTFSQVNSITASLETSFGLEPPLVSVITAISIAFVVFGGIEKISDVSTKIVPFMAILY
                     ILASITVLAVHWDQLLPTLALVFKSAFTPAAAVGGFAGATVQQAIQRGIARGVFSNES
                     GLGSAPIAAAAAKSDNPVEQGLISMTGTFIDTLIICTLTGFTILVTDQWSVEGLAGAP
                     LTQAAFATVFGNTGSIALTISLVLFAFTTILGWSYYGERCIEFLFGTKSILPYRLVFV
                     AMVALGGFLKLDLIWTIADIVNGLMALPNLIALLALSPVIIKETRQYFAKKK"
     gene            6530..7378
                     /locus_tag="AC1PIV_000542"
     CDS             6530..7378
                     /locus_tag="AC1PIV_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HIP6611590.1"
                     /translation="MNDFITKYLSQFNIEAIVTAGLNKVLSLVLLFVAFYIIKKIAKA
                     SVKKVLVPSLKVSTQDIGRQKTISRLVESILNYLLYFILIYCILSILGLPVSSLLAGA
                     GIAGVAVGLGAQGFLSDLVNGFFILIERQFDVGDVVKLTNGPITISGTIVSMGIRTTQ
                     VRDADGTLHFIPNRNILVVSNQSRGDMRAQIDIPLKFNTDLEQVYRVIEEVNLREISN
                     FDQITGVTVLGPQNAISGQFVFRVNLFVANGQQNKIYHQFFGFYQDALRQAGIDLPSS
                     GPTVLK"
     gene            7389..7976
                     /locus_tag="AC1PIV_000543"
     CDS             7389..7976
                     /locus_tag="AC1PIV_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HIP6611591.1"
                     /translation="MQTKDFVVENGQMYYKKKPLHKQPLFWTTIAGAVLSFILGVTCF
                     IFMIGLSSANFDNWDTGSDGYIDETVEYTEYQVGDSVDFSNGLHVTVTSMGKDDSIEL
                     VDSYYSTAYVVEMEVENSTAKELYFDEYYFSLMDPVSQIPFTLDLRTYDVNLVEKLKP
                     GEKVQVKLIYGIDNETNFGFTYEDAMWTELVAEGI"
     gene            complement(8212..9558)
                     /gene="gdhA"
                     /locus_tag="AC1PIV_000544"
     CDS             complement(8212..9558)
                     /gene="gdhA"
                     /locus_tag="AC1PIV_000544"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HIP6611592.1"
                     /translation="MSNAKAYIQASFEAVKARNPHETEFLQAVEELFSTLEPVFEAHP
                     EYIEENILARIVEPERIISFRVPWTDKDGNVQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQSILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEIMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYMYGQYKRLRQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     FTDNMLAANGKSFKDQTVLISGSGNVAQYAVQKATELGAKVISVSDSNGYIIDETGID
                     FDLLVDIKEKRRARLTEYAAEKSTAKYFKGSVWNYDGKADIALPCATQNEINGKQAAA
                     LVKNGVYCVAEGANMPSDLDAIKVYKENGVLYGLAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMANIFNTAKETAEKYDLGTDYLAGANIAAFEQIADSMIAQGLV"
     gene            9780..10715
                     /locus_tag="AC1PIV_000545"
     CDS             9780..10715
                     /locus_tag="AC1PIV_000545"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006597158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HIP6611593.1"
                     /translation="MVSTVTTLGGFTFDNCLMNAAGVWCMTKEELDAVKNSKAGTFVT
                     KTATLDYRAGNPEPRYQNVPLGSINSMGLPNQGLAYYLDYLLELQETEPERTFVLSVV
                     GMSPDETHEILRTVEASDFKGLTELNLSCPNVPGKPQIAYDFETTETILQEVFTYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNQFPLKFVNCVNSIGNGLYIKDESVVIKPKNGFGGI
                     GGEYIKPTALANVHAFYQRLKPEIQIVGTGGILTGRDAFEHILCGASMVQVGTTLQKE
                     GVAAFGRITAELQAIMAEKGYETIEDFRGKLQQDD"
     gene            11048..12280
                     /locus_tag="AC1PIV_000546"
     CDS             11048..12280
                     /locus_tag="AC1PIV_000546"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0045227 - capsule polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HIP6611594.1"
                     /translation="MERRANYIRRKRYASYRTKMHLFFICGLATIILAIIIVSEHLVP
                     RLNQASESMHSDNSVRIMAHGDLLYHLPILRGAEQPDGSYDFSENFTYVKPWIEQADF
                     AIADFEGTISPDIELAGYPLFNAPAIVANNIHDAGYDLVDLAHNHILDSHLSGLISTV
                     NTFRDAGVDTVGVYAEGNRATAPLYIREVNGIRIAVLAYAYGFNGMEALLSQEEYDAY
                     LSDFDKEKMRAEIERAEKEADITIVMPQTGVEYQLEPTEEQTSLYHQMIDWGADIVLG
                     GHPHVVEPTEILEKDGQRKLIIYSMGNFLSNQRIESMEDTPNAQWTERGVLMDLTIQK
                     ENGQTSIQTAQAHPTWVNRLSKGTYSTDGYEQFSYQTYILEDWVAGGRYYGQLDLDTQ
                     ARVDTAYQEMKDFVNLVW"
     gene            12292..13119
                     /locus_tag="AC1PIV_000547"
     CDS             12292..13119
                     /locus_tag="AC1PIV_000547"
                     /EC_number="3.-.-.-"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012774938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HIP6611595.1"
                     /translation="MIVRLIATDMDGTFLDGQGNFDRERFSRVLDQLDQKKIPFVIAS
                     GNGIGRLLQLCQGFEDRLIFVADNGAHVYQNGKTVIRRAIQQVEVEAILHFFKGRWAD
                     VCLMLSNDGNIYMQAGAGMPFAGTDLPIELAQMAAFQNRVTYLDNLSAYPVSESIHKV
                     GLWVPEARVESITEAFNQGFHGQLVAVTSGYGSVDILPQGIHKAWGLEQVLTGLDIEP
                     EQVMAFGDSDNDIELLSYVGYSYAMENATDKVKAVAKYMAPSHLEAGVLQVIEEYIL"
     gene            complement(13168..13950)
                     /locus_tag="AC1PIV_000548"
     CDS             complement(13168..13950)
                     /locus_tag="AC1PIV_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIP6611596.1"
                     /translation="MKKYISLYLYNIKVYMMAQMSFRVDFFIGLFSSLIEQIVYLIFL
                     NILFGNIKEIAGFNYGQMLFIYGIATVGRSIHLIFFDNLWMFGSRYIRQGEFERLLLM
                     PVNPLFQLICERIQPQGIGTTLIGSLALVQASNELGMEWSLGKLALLIFIAICIGLLY
                     AAIQLGPTALAFWIVESFPLTMGIFALNQMAQYPLNIYPKIIQILLIFVFPYAFTAYF
                     PALYFLDLSMWGLALPLVVVVLFSINYNLFRYGMTKFTSVGN"
     gene            complement(13952..14731)
                     /locus_tag="AC1PIV_000549"
     CDS             complement(13952..14731)
                     /locus_tag="AC1PIV_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002941063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIP6611597.1"
                     /translation="MRKYLYMTRLTMMNAMQYKAFFLATFVSLAVKILVALYVWKTIF
                     FTQSEVNGFTLQTFTTYIIFANLLASLNSFSLGEDLSYSILKGSIAGEFLRPYSFILA
                     LFFKDLGNKLLELIKFAIVFIGILLVHQDFYLPDGKTILLFLVSSILGMFIVQLLDMA
                     FGFLAFFTVNAWGVMLLRMGLFNLASGALLPLSFYPQAVENFLKLLPYNYAVNVPVSI
                     LLGQESDLTALGLQVIWIPILACFIAALWSQAKRRIVIFGG"
     gene            complement(14724..15707)
                     /locus_tag="AC1PIV_000550"
     CDS             complement(14724..15707)
                     /locus_tag="AC1PIV_000550"
                     /EC_number="7.5.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002941065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIP6611598.1"
                     /translation="MIQAEHLSKTYSIIDKEVGLKGSIKAFFKPKKKSIPAVQDISLQ
                     VGKGKIIGYIGSNGSGKSTTIKMLTGVLFPDQGQVRINGLNPQENRKAVNKQIGVLFG
                     QKSHLDWNLPVQESFILHAKIYDVPDKVFKERLAVLIELLDLADIMKQPIRNLSLGQR
                     VRCEFAAIFIHQPAVVFLDEPTIGLDASVKETIRSFIRYMNQEYQTTFLITSHDMKDI
                     ESLCERIFIIDKGKKVYDGSLTVLKERFSTVKTILFSTEKPIEKDLQLEGWEFIRKDD
                     FHFEIHYQSKVWTSAQVIEQVFNHYSIEDVTMKELEIETMVRQIYEEGIHA"
     gene            complement(15792..16325)
                     /locus_tag="AC1PIV_000551"
     CDS             complement(15792..16325)
                     /locus_tag="AC1PIV_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HIP6611599.1"
                     /translation="MRTDSRKERTRQAILEAMVTCLESQGFNDITTTHLAQTAGISRS
                     SFYTHYKDKYELIDSYQQGLFHKLEAIFDHYDGNRQSSFLEIFELLYREKLLSALLTH
                     NGTQEIQNFLINKVRLLVANDLAERLGKENLSQLEKEYSSIYFSHAFFGIMQVWIKNG
                     KQESPQYMTDFLIKMLP"
     gene            16451..18910
                     /locus_tag="AC1PIV_000552"
     CDS             16451..18910
                     /locus_tag="AC1PIV_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012774941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HIP6611600.1"
                     /translation="MLQKVKNIFKKPMTLITILGIACVPALYNISFLTSMWDPYGRLD
                     QLPVAVVNQDQSASFQDKTLTIGDDMVDNMKESKSLDFHFVSEKNAEKGLEEGDYYMV
                     ITLPEDLSEKATSLLTNQPEPITISYQTSKGHSFVASKMGESAMEKLKTSVSETITKT
                     YTTAVFDSMREIQTGMIEAADGSQKLTNGASQLESGSQTLSNGLTTLTTSGQVLVTGA
                     NQLATGVVSYTDGVNQAATGSQTLSSGLTIYTNGVASLVSGAEQLNANSSQLITGVGQ
                     LQSGASQVEQLVTGANQLQAGLEQLANSTSLSAEQSSQIQALLTGLPQLQVAINQLND
                     SLSSIGGLAVDNSTLSSLLTEMGAQAQGLLTAAQADKTASIEALQTTATYQNLTADQQ
                     AELVGALQNSPSATATVAQTILDQLSQLSQTLSSLQSLSGMATQMNQLQSAVGQINTA
                     ANQALPGATTAIESLSSGLSQVNTALNQQVLPGTQTLTSGVSQLQTQLSSGASQLMFG
                     VTAYTAGVAQLAAGGAQLVANNSSIQSGGGQLTSGLATLASNSSQLVSGSEQLASGSQ
                     QLIAGADQLASGGQALTSGISSLRTGSETLTNSLSSASQQLSVVSVEDKNAQAVSQPV
                     TLEHSDQDDVKTNGVGMAPYMVSVALMVAALSANVIFVKHIDNRSYKNRWDWAKGKLL
                     LNGIIASLAAVILYGVLRLIGIEPAHPMATLGIILLASWTFMALVTALVGWNNRFGSF
                     ASLIILLLQLGSSAGTYPIELSPRFFQVIQPYLPMTYSVSSLRQTISMVGNSSHQVWM
                     LSLFLVGFMGLGLLIYNQKDE"
     gene            complement(18960..20018)
                     /locus_tag="AC1PIV_000553"
     CDS             complement(18960..20018)
                     /locus_tag="AC1PIV_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat-containing
                     protein"
                     /protein_id="HIP6611601.1"
                     /translation="MKKKLTIAIIIGFVSLIAGLILAGIGFFTGGITRLEEVAAPTEV
                     HKTFTDLNTIKIDFIPHSVYIKESSDNNYHVTYANSDNNIQNPLKLSEKDGVLTLSAQ
                     ELEFAIEGIMQYLGESLAQRRINVFSVTIEVPKGKTLDKLEGHNLHFYDFGGFTIENI
                     HIKEANLSGGVTLDKVTIDSGQIEAGYFQATQSTLKDMHINLQGSSVRLYETSLENVT
                     IEGYSQLDSRQTTLLGDNRFTPSDTYSSTTFLDVTDKSLADSNLLITNQIDKKKLVEA
                     QGYYYEDGNDLGEMVNQDPYLKERLGEVGIFTSDKYTKFPVKTENDLQTLTLENKGSK
                     NKLTIEATNATINLGTPK"
     gene            complement(20015..20770)
                     /locus_tag="AC1PIV_000554"
     CDS             complement(20015..20770)
                     /locus_tag="AC1PIV_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HIP6611602.1"
                     /translation="MTRTEYMEQLEKYLKKLPHKEYFEAISFFNEYFDEVGPERETEI
                     IEELGSPKEAASELINNMLNKQIQEEKDQQEPIQLNWKLWVGLGALSMTGLFSFFLLF
                     IMGEFIGVIPLFATLILGAFFLGRYFRNFSQTKRTLWLAILAVISLPIAIPLLLILLA
                     SLLGLVALILALIVGAFVLGVGLLTSGGYLIWEAFSLMSEGFNIFLMGFGSGLSLIGG
                     AILIYILTGFFAYWSWRLVKACFKWILKRGKRA"
     gene            complement(20757..21083)
                     /locus_tag="AC1PIV_000555"
     CDS             complement(20757..21083)
                     /locus_tag="AC1PIV_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HIP6611603.1"
                     /translation="MHFPVPAVLTEFLIMAILESDDSYGYEICQTIKLIANIKESALY
                     PILKRLEQNDFLTTYSQEYQGRMRKYYSLTQLGHEELVRLKDDWDTYTNTINGIIEGS
                     VRHDKN"
     gene            21392..21772
                     /locus_tag="AC1PIV_000556"
     CDS             21392..21772
                     /locus_tag="AC1PIV_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HIP6611604.1"
                     /translation="MKLYVQFMIILVFSFLGEAISTIFHLPIPGSIIGLILLFLALEF
                     KLIRLRHIHTVGNFLLANMTILFLPAAVGIMERFDAIKDYLLPIIVVILGAIFLNILV
                     IGFVVQFVKQKFEGDYIDAEGNHD"
     gene            21765..22460
                     /locus_tag="AC1PIV_000557"
     CDS             21765..22460
                     /locus_tag="AC1PIV_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HIP6611605.1"
                     /translation="MTELFSNPIFGIMLSIAAYLIGMLIYRRFPHPITTPLLVATGLI
                     IVFLKMTGISYKEYYAGGSYLNMLIVPSTVALGIPLYRSFHLMKHHIRSILLGIFVAC
                     IVNTVFTALIAKWFGMDFFLAISLFPKSVTTAMAVGITDKMQGIATVTLVVVVATGIL
                     TSVLGPVFLKLLKIEDPVAVGLALGGTGHAIGTGTAIKCGHTQGAMAGLAIGITGIMY
                     VVISPIVAQIILQ"
     gene            complement(22493..23293)
                     /locus_tag="AC1PIV_000558"
     CDS             complement(22493..23293)
                     /locus_tag="AC1PIV_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HIP6611606.1"
                     /translation="MGANQETLMYTLEKSIKKKADLFEHSFSAYAVRSILASLYLGLG
                     IVISLYTADKLNHVAEGLGKFSYGLMFGWGLLMILYMNAELGTSNMMYMTVASHRKTI
                     PTKTALKMLATCILFNFVGAVLVCYLVSLTLPYQHVDAHSYLFEATVAKLSKTPLTQF
                     IEGIFANIVVNIGVFTFLRIKDDAGRLISVIFIIFIFAFLGYEHVIANFSLFSLAFFA
                     NGGPVEGMTLLSVLSNFLFSGLGNYVGGGLFIGLLYSWLNNQSKLYVD"
     gene            23434..24279
                     /gene="gla"
                     /locus_tag="AC1PIV_000559"
     CDS             23434..24279
                     /gene="gla"
                     /locus_tag="AC1PIV_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aquaglyceroporin Gla"
                     /protein_id="HIP6611607.1"
                     /translation="MDVTWTVKYITEFLATALLIIIGNGTVANVDLKGTKGNNSGWIL
                     IAIGYGLAVMMPALMFGNVSGNHINPAFTLGLAVSGLFPWAHVAQYIVAQLLGAMFGQ
                     LVVVAVYKPYFLKTENSNHILGSFSTISALDNGTKESRKAATTNGFLNEFVGSFVLFF
                     GALALTKHFFGSELVGKLIEQGYDKTVAETMTAPYTSGSIAVAHLGIGFLVMALVAAL
                     GGPTGPGLNPARDLGPRIVHALLPKSVLGENKADSKWWYAWVGVCAPIIASIAAVALF
                     KFLYL"
     gene            24408..25940
                     /locus_tag="AC1PIV_000560"
     CDS             24408..25940
                     /locus_tag="AC1PIV_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase HerA-like domain-containing protein"
                     /protein_id="HIP6611608.1"
                     /translation="MSDVIAFGYGSSRAKMQLKRLNRHGIIAGATGTGKTVTLKVLAE
                     QLSDAGIPVFLSDIKGDLNSLVAANTKEIDPSRLEKTHYLDYSPVGYPVELWDVLGEN
                     GTPIRMTISELGPVLLTRLLGLNDTQESILNIVFSVADERGLLLIDLMDLRAMLNFVA
                     ENAAELSQYYGNIPARSVGAILRSLVVLEQQGGKIFFGEPSLDIADLMRTAEDGRGVI
                     NVLQATQLFNQPTLYSTVLLSLLSELYEVLPEVGDLDKPKMVFFFDEAHVLFKDAPKV
                     LLEKIELIVRLIRSKGVGVFFVTQNPTDIPDSVAAQLGNRIQHGLRAFTPKELKTVAT
                     VAETFRQEGDEDLAKVIQELQVGEAVVSTLQADGTPSFADRVLIYPPKSMLGTVEPSA
                     LLSVINNSPLMEKYADAVNRESAHEQILAMTEAKEAELIKKAEQAEAEKQAEKEAKAA
                     AKMEEKAQKEAAKTAQKTSQPASRKTDSMMDRFTKNLMSQVGREVGRVVTRGIMGMLK
                     GK"
     gene            26052..26660
                     /locus_tag="AC1PIV_000561"
     CDS             26052..26660
                     /locus_tag="AC1PIV_000561"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016817 - hydrolase activity, acting on
                     acid anhydrides [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0009132 - nucleoside diphosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HIP6611609.1"
                     /translation="MTDQLQALLKDYQPQPLGEKRSYAVFLPLVWSDNQWQVLYEIRS
                     ESISQPGEVSFPGGGVEVGETPQQAAVREVMEELNIQPEQIDILGEIDYLVLECSTVH
                     CFVGRLNLDWTTILPNEEVARIFTVPLSTLLTTQPVYYQLDSQIVPDCDFPFERLRGG
                     VDYPFSHHKRSVPFYENLSENIWGMTAQFTHRFTEIVKSNLS"
     gene            26950..29247
                     /locus_tag="AC1PIV_000562"
     CDS             26950..29247
                     /locus_tag="AC1PIV_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HIP6611610.1"
                     /translation="MSKQKVVSSLLLSTVVLGGLAFYSTTTVKAESLEPDVTSVNASD
                     ATNKPVVPNEEGGDFLAEEELEDDDTLEEELNEKAEEVTEPSSPEALLQPRAMMSDSE
                     TSGMEEIPMNDEPSDNTEEKVEKQQSPLIQTSNADYKSGKDQEKLRTSVSINLLKAEE
                     GQIQWKVTFDTSEWSFNVKHGGVYFILPNGLDLTKIVDNNQHDITASFPTDINDYRNS
                     GQEKYRFFSSKQGLDNENGFNSQWNWSAGQANPSETVNSWKSGNRLSKIYFINQITDT
                     TELTYTLTAKVTEPNQQSFPLLAVMKSFTYTNSKSTEVTSLGAREITLEKEKTLPPKE
                     NPKPEPEAPKPDAPQAPSAPESPTEEPKKEDAPQTPQAPSTPEKQPEVPESPNPETPD
                     APSTPKDEPQAPSIPEEKPQVPEEPKQEAPSAPSTPEKQPEAPESPTEEPKKEDAPAP
                     STPEKQPEVPESPNPETPDAPSTPKDEPQVPSIPEEQPKETPAPEEPKKEDTPQTPQA
                     PSTPKEEAPKEEVPTPPAPSVPEEQPKETPTPEVPKQEDVQPEAPKSDKVESDKQMPE
                     TKKPDMKQPKADDMPKEQKPKADEPKAEQPQMDKPQMEAPKKDSEAPKSDKVETDKQL
                     PETKQPDMKQPKADDMPKEQKPKADEPKAEQPQMDKPQMEAPKKDSEAPKSDKVETDK
                     PMPETKQPDMKQPKADKPEAEKAQMPRTEGMKPESKASMMPKAEAPKATLPNTGEASS
                     AIGWLGGALATLATGLYLFKNKKEE"
     gene            29682..30401
                     /locus_tag="AC1PIV_000563"
     CDS             29682..30401
                     /locus_tag="AC1PIV_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HIP6611611.1"
                     /translation="MSKQKVVTNLLLSTAVLGGFLICHAPSVSAETGNLQEIPTESAT
                     VSSENQTATAVDGISPTDNQLPTSEEGDKQAPEEKLVSSDSTREESATQVATDPDAPS
                     QSLSVSGAEISTADSNIQQAEEKLIQESNYYRFDTHQGEQIRKAVSIEKISADNDEIK
                     WKVTFDRKNWTFSGEGSGYYFILPKGLQLTKIIDSQSEEDIFNKFPKDVNSEANSGGQ
                     PYRFFSREKNANNDERSFESQ"
     gene            30531..31721
                     /locus_tag="AC1PIV_000564"
     CDS             30531..31721
                     /locus_tag="AC1PIV_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HIP6611612.1"
                     /translation="MTNREMQTFPVLAVVKNFKERIFFSRDEITSAAGLRLKVSESAK
                     PNNEGITIIGDSSPESDRTPEPRGDRTPDIDVPKAEVPKVEQPKPKAPEVQLPAPKAP
                     ESVPPKVMPPAPKVPDVKTPKVEYPDTDAPEIESPKAPETERPEVLPPTPKVPEVEVP
                     KVIPPTSKVPEAELPKVEQPKPKVPEVHLPAPKSPETEPPKVMSPAPKVPDVKTPKEA
                     PLPPKTPGVEVPKVIPPTPKAPEVEVPKVTPPTSKVPEVETPKVEQPKPKVPEVHLPA
                     PKSPEVEVPKVTPPTSKIPDVKTPKSPEVAHPEVEKPAGIQPEKGQPEVNKPNIIHSE
                     VLQSEVKKTESGVSMAPKVGIQKETLPNTGETSNTLVWLGGALATLASSLYLFKQHRQ
                     REEE"
BASE COUNT         9503 a         6170 c         7209 g         9162 t
ORIGIN      
        1 aaaacatgtt gattttggtt acgggttcta atgataggga ggtggtggag tccacctcct
       61 ttttgtgcaa atggggttcg ttatgaaaaa agtatttact tatttatcta cttttagcgt
      121 ctgtctcttc tgtatatggt tagtgagtct gcaactcgat tctttaattt atcattacta
      181 tccatcggtt tccatattaa gtcgagggga agaagtgacc tatgaagaag tgtcggatgc
      241 cctgacaaat ttagctgaaa aggaaaatag tctaattgct aagacaataa cagaaacaga
      301 tgatagtggg cgaactacta ccagttatga tgtttttggg aagggggagc ttccacaggg
      361 cttggtcaaa gcggataggt tagtagctag tcaggccaac ttagctgaaa attactatgt
      421 tgtaaaaggt aatctggaca tcaaagtggt agaaaacgtc ttacagtcac tgggattggt
      481 ggatagctat atttatagac cgaccctatt aaacagttta agtctatttc ttggtagggg
      541 agctccgagc ttaggcctta ttatctttat actcaccaat cttgcattga cagtagttgg
      601 gcagattgtc tacttgcggt cggcaggtat agagatgctt tcaggggtga ggagttggca
      661 gattgctagt cgttttttaa gagtggatgg aagagatata gcattggcta caggaggagc
      721 gcttgttttt ggattaattg ctattttaat tttgggttgg ccaatggtat attatcgttt
      781 tgtagcaatc ggtatcgcct tttatgcttg tttgcttttt ttcctatctt tatcgacaag
      841 tattggattc atgattgcat taaacatttc tcagttacaa aagctaatta agggagcttt
      901 gcctctcaag gcgatttttg ctattttact agtaggtcag tgtttagcgg tttgcatcat
      961 ctctattggt gctagtcgaa cgttgacata tgttggagtt ctccatacac taacgatagg
     1021 agaaaaggct tggcaagaaa gacaagatgt ttttagtctg tctttgaatc gtgaagcatt
     1081 catagctgat gaagcgatgg cccagcaaca aagaatggct tggtctcatg taattttaga
     1141 atcatatgcg aaaaataatg taatgttagt ccagcaccat ttacggcata acacaataaa
     1201 agaacatacc atcattgaat ccagcaagga aattcctcta gaaagggtgc tgtatgtgac
     1261 gccgaattat atacaatcag aaggtggact gtacgatttc aatcagctgg aagagataaa
     1321 gcaattaggt aaaggagaaa ttgcattatt attaccaaag agtttgcaaa atgatgcgag
     1381 tgtttaccaa gcgtattttg aggacatggt aggaaaattg cttgcggatg gagaaggatc
     1441 cataagtttg cattcaaatg tttattacat ttccgatgag aagcgatggt tcatttacaa
     1501 tcataccccg ataaattatg agcaattttt acaggctccg ttgattgttg ttctatcacc
     1561 tgaaagtttt gaagaaacgt cctatttttg ggaaaatgcg ttaccagatt ttgtattttt
     1621 caaagataaa gagatgctgg aacaactgtt ggacaaatac aatttacaaa acacaatagg
     1681 tagcttgtta tctagcaagc aacattacaa caccctgaga aaaaatgttc aacttgaaat
     1741 tcttatgacc ctatctccga caatccttgg aatattcact tccatactat tgttcaatac
     1801 gatgaatctt ctatactttg agaccttcaa aagagaaata gccatcaagc ggatagcagg
     1861 gatgggtttt atcgaattgc atggttctta tctaggagaa caagtcggct ccgctcttat
     1921 tgggatgggt ttggcaatgt ttatgacaaa gtcagttatt gttagcctag gagtagttgt
     1981 ggctttgttg ataaatagtt ggatgttact gaacaatcaa gcgaaaaggg aagaaaaaat
     2041 ccagttgagt gtattaaatg gcagatagtt aatgaggtga agttagaatg aaaggaaaat
     2101 ttgtacttgt atcgacgatc attctagccg tctttatgat ttggttgggc gtcagtcaaa
     2161 aggagactat gctagttcat tattatcctt ctgtgactac tttgtcggta tctgaggacg
     2221 tgacatattc agatgtacga cagcgattag aagactattc tcaacagacg gatagtgtca
     2281 ttgccagacg agtgattgag ccaagtaaat caggtggacg taccttttct tatgataatt
     2341 ttagtcaatc tcccctacca agaggactag aggaatttca ggcatcagaa aaggtggagt
     2401 ctgcactttt aaccaaatat tttattttcc aagggaaagc gacggtagag gagcttcggt
     2461 ctcttcttgt ttcgcttgga cttgatgaag ttcagattcg gaagccttcg actattgcta
     2521 ctttactcgt atttctgacc caaggtggtc aattcttagc cgtactggtc tttcttatta
     2581 cgtatatggc tttggtcgtg attgctaatg taaggcagtt gcgtacagca ggtatccgtt
     2641 tgattgcagg ggattcgcgc tggcatttat ttctactatc tctacaggaa aatgcgaaag
     2701 agatagctct aactatccca tttgcggttc ttccagcagt tggactggcc tacctcgttg
     2761 gattagatgg ctattctgtc tactatctgg tcgcagctct agtgggctat catttcttgc
     2821 ttggtttgat tgtccttttt ttcgctgcta catttacctt ggccattcga acctatcact
     2881 ttttaccctt gttaaaaggg aagatgcccc tgcaagggat cctgaccatt atggttatgg
     2941 gacaaatgct ggctctattg gtggtgtcat ttgggatggc tcaaaccgtc tattattcag
     3001 ggatttggca ggaatatcaa gcaggtgccc agcagtggga gaatgaaggg gattactata
     3061 gtttagcttg gaatatttct gcggatggtc gctcaggact aaattcgcct gaaaattggt
     3121 atcctttact aaggcaagct ttggaggaag acggcgcact ctttgtcaaa agtaatttga
     3181 atgcctattt aatgggcttc caactggaag atggaacacg ccttgacagc taccatccag
     3241 ctggaaacac cctctacgtt agtccaaatt atttgcagat acaggatgta gacttagcag
     3301 aaggagaagt agcgctccct ttacaagaag gagaatttca acttctgttg cctgaaaaat
     3361 tgcgccctga aagcgatgct tatctccatc tttaccaaga ttatatcaat cgtatggtta
     3421 gacctgctaa tcaagcacgc tcagctacca ttaagggaaa agttgcctat ttaaaaaatg
     3481 ggcagaagca gtttatctac aatcatcgtt ctggtcaaca tgtgcaatac ctgacagacc
     3541 ctattttagt tgtgctggca ccgtcaagtc tgggaaaaga atctgctgac ttttggttga
     3601 atgaagtaga tagcagtatg ctatttaaaa acagagataa acttttacgt gaattgaagg
     3661 caagaaattt gtttcagttt gtcaatgaag tgagaagtag ttcttccctc tttacggaac
     3721 ttttagatcg tattcggata gagaccattt caacatctat gggtgccatt ttagggattg
     3781 tgacatcaat tgtcctgttt aataccatga atcttctata ctttgaagaa tttaaacgtg
     3841 agattgtcat caaggaaatt gcagggatgg gtttcttggg aatccataag aaatacctaa
     3901 cgcttcaact gctttctctc ttgttggctc ttggagcaag tatggtagta acaggtcaca
     3961 tttttataag tagcatcagt tttgccttgt ttatggtcaa tgccctctgt ttattgaggt
     4021 ggcaggcgag gaaagaagga gcttggaatg tccgtatttt gaaaggagcc tagtatgttt
     4081 tctgtccaat caattcaaaa gaaatttggg aagcgcagct tgttttctga tgtaacacta
     4141 gacttgcagg ctggaaaggt ctatgccttg ataggtgcca gtggtagcgg aaaaacgacc
     4201 ttgctgaata ttttagccaa gttggagtcc tatgatgcag gtgacattct ctacaaggga
     4261 aaggatttga aaaagttgaa gccccatctc ttttttaggg aggaattagg ctatctcttt
     4321 cagaattttg gtcttttaga aagtcagaca atcaaagaaa atctggattt gggactgatt
     4381 agtcagaaat tgtccaaaga cgaaaggaaa tcgaggcagg aagcggcact tgatgcagtt
     4441 ggtctgtctt atctggacct gtcccagcct atctatgaac tctcaggagg ggaagcccag
     4501 cgggtagctc ttgctaaagt catcctgaaa aatcctccat tgattttagc agatgagccg
     4561 acggctgcct tggatcctaa gagctcccaa gaaattatgg atattttgtt atccttgaag
     4621 agcccagatc ggttaattgt gattgcgacc cataatcctt tgatttggga gcgagcagac
     4681 cttatcataa aaatggaaga cttgtaaaaa ttcatactct tcgaaaatca aaattatccg
     4741 ttgtcaactt accttgatga actccagttc tatcttcggc ttcgtttcct aggctacttt
     4801 tgattttcat tgagtatcag aaaatattct tgattttttc gtgaaattag attaaaataa
     4861 aactagataa aactgaataa ccggttgata ttgggtagaa gggaaactga ctgttcaatg
     4921 gacggaactc tggagagacc attttggcac cgaaggggca aggtagtcct gcttggaaaa
     4981 gtagagctac tgaaactctc aggtaaaagg acagagcgtt gaaaaatagg ctttttctgt
     5041 atttttcacg ttgattctag aggttgaagt gttcagcctc tttttgtttt tccggcagct
     5101 ttatcgggtt agaaacgctt aggaggaact atgttagaac tatttaaggc tatcaacaat
     5161 cttgtttggg gaccgcccct cttgttacta ttggtcggaa cgggtgtcta ttttacccta
     5221 cggttgggag tatttcagat tggcaaattg ccgacggctt ttcgtctgat tttctccagt
     5281 gaccagtctg gtcagggaga tgtgtccagt tttgcggctc tgtgtacggc tttagcagcg
     5341 acagttggta caggaaatat cgtcggagtt gcgacagcta ttactacagg tggtcctggg
     5401 gctcttttct ggatgtgggt tgcggccttt ttcggaatgg caaccaagta tgcggaagga
     5461 tttttagcga ttaaataccg aaccaaggat gccaacggtc aagcggcagg tggacctatg
     5521 cattatatca ccttggggat gggacagaag tggaaaccct tggcagtttt ctttgctatt
     5581 tcaggtgtat tagtagctct cttggggatt ggaacttttt cgcaagttaa ttccatcact
     5641 gcttctttgg aaacgagttt tggattggaa ccgccacttg tcagtgtaat aacggctatt
     5701 tcaattgcct tcgttgtttt tggtgggatt gaaaaaatct ctgacgtttc gaccaaaatt
     5761 gttcctttca tggcgatttt gtatatctta gcaagtatta ctgtcttggc cgtgcattgg
     5821 gatcaactct tgccaaccct ggccttagtt ttcaaatctg cctttactcc agcagcggct
     5881 gtgggcggtt ttgcaggtgc gactgtgcaa caagcaattc agcgtgggat tgcgcgtggg
     5941 gttttctcaa atgaatctgg tttgggttcg gcgcctattg ctgctgcggc tgccaagtct
     6001 gataatccag ttgaacaggg cttgatttct atgacgggta cctttattga tacacttatc
     6061 atctgtacct taacgggttt tacgattcta gtaactgacc agtggtcggt agagggcttg
     6121 gcaggtgctc ctcttactca ggcagctttt gcaacagttt ttggcaatac aggatctatt
     6181 gccttgacga ttagtttggt actttttgct tttacaacta ttctcggatg gtcttactat
     6241 ggtgaacgct gtatcgaatt cctctttggc accaagtcta tcttgcctta ccgtctggtc
     6301 tttgtagcta tggttgcctt gggtggtttc ctcaaactag acttgatttg gaccatcgca
     6361 gatattgtga acgggctcat ggcactacca aacttgatcg ccttactagc tctctctcct
     6421 gttatcatca aggagacacg ccagtatttt gcaaagaaga aataagataa aagtcagcca
     6481 cttggctgtc tttttgttct tttagggtgt tttctgctat aattatctca tgaatgattt
     6541 tattaccaag tatttgtctc aatttaatat tgaggccatt gtgacagcag gtctaaataa
     6601 ggttttatcg cttgttttac tctttgttgc attttacatt atcaagaaga tagccaaagc
     6661 ttctgtgaaa aaggttttgg ttccctctct aaaggtatct acccaagaca ttggtcgtca
     6721 gaagaccatc agtcgtctgg tggaaagcat cctaaattac ctactctact ttatccttat
     6781 ctactgtatt ttgagtatcc tcggtttacc ggtatccagt cttcttgcag gagccgggat
     6841 tgctggggta gctgttgggc tgggcgcaca aggttttctc tcagacttgg tcaatggatt
     6901 ctttatctta attgaacgac agtttgacgt cggagatgtg gttaagttaa ccaacgggcc
     6961 cattaccatt tcaggaacca tcgttagcat gggaatccga acaacacaag tacgtgatgc
     7021 agatgggaca ttgcatttta ttcccaatcg caatattcta gtggtgtcca atcagtcaag
     7081 aggggacatg cgtgctcaaa tcgatattcc gctcaaattt aataccgatt tggaacaagt
     7141 ctatcgcgta atagaagagg tcaatttgag agaaatcagc aattttgacc agattacagg
     7201 tgtgactgta ttaggtcccc aaaacgctat ttcgggacag tttgtatttc gtgttaatct
     7261 tttcgtagcc aacggtcaac agaacaagat ctatcatcaa ttctttggtt tttatcaaga
     7321 tgctctgcgt caagcaggaa tagatttacc ttcaagtggg ccaactgttt taaaataagg
     7381 agtttattat gcaaacaaaa gattttgtcg ttgaaaatgg gcagatgtat tataagaaga
     7441 aacccttgca caaacagcct ctcttttgga cgaccattgc tggtgccgtc ctctccttca
     7501 tcctaggagt aacctgtttt atttttatga tcggcctaag ctcagcaaat tttgataatt
     7561 gggatacagg tagtgacgga tacattgatg agactgtgga atacacagag tatcaagttg
     7621 gtgactcagt tgatttttct aacggtcttc atgtaacagt aacatctatg ggcaaagacg
     7681 atagcataga actagtggat agctactaca gcacagctta tgttgttgaa atggaagttg
     7741 aaaattcgac cgcaaaagag ctctattttg atgaatacta tttcagtctc atggatcccg
     7801 ttagtcagat tccctttacc ctggatttgc ggacctatga tgtgaatcta gttgaaaagt
     7861 tgaagccagg agagaaagta caagtaaaac ttatctacgg tatagataat gaaacaaact
     7921 ttggttttac ctacgaagat gccatgtgga cggaattagt cgcagaaggt atctaattgc
     7981 tgtagaaaaa gttttaaata ttgcacaatt ttgcggtttt ataacgcccc ttggttcaga
     8041 ttgttcggct tggtaattgt actatatccg acttatctgt tatttttaca tttaaaaaag
     8101 gagaatatgt ttatccactg ttctcctctt cttttaatga aaaatacccc caaaattagc
     8161 acgtcaattt tgggggcgtt tttattatag tttagtaaac taaaagtaag cttataccaa
     8221 accttgggca atcatgctat ccgcaatttg ttcaaaggct gcgatgttag cacctgcaag
     8281 gtagtctgta ccaaggtcgt atttttcagc agtttctttg gctgtgttga agatgttggc
     8341 catgatgtct ttaagacggc cgtctacttc ttcacgagtc catgacaagc gaaggctgtt
     8401 ttgactcatt tcaagggcag atacagctac accaccagcg ttggcagctt ttgcgagtcc
     8461 gtagagaacg ccattttcct tgtagacttt gatggcatca aggtcagatg gcatgttggc
     8521 accttcagcc acacagtaca cgccattttt tacaagggca gcagcttgtt tgccgttgat
     8581 ctcattttga gtcgcacatg gaagggcaat atcagccttg ccatcgtagt tccatacaga
     8641 acctttgaag tacttagcag ttgatttttc tgcagcgtat tctgtcaaac gagcgcggcg
     8701 tttttctttg atgtccacca agaggtcgaa gtcgatacca gtttcgtcaa tgatgtaacc
     8761 atttgagtct gaaacagaaa taacttttgc accaagttca gtcgcttttt gaacagcata
     8821 ttgggcaacg ttaccagaac ctgagataag gacagtttgg tctttgaagg atttaccgtt
     8881 tgctgccaac atgttatcag tgaagtaaac caaaccgtaa ccagttgctt ctgggcggat
     8941 caatgaacca ccgaagccaa gaggtttacc agtcaagaca cctgcatcaa actggcggag
     9001 gcgtttgtat tgaccgtaca tgtaaccgat ctcacgacca ccgacaccga tgtcaccagc
     9061 agggacgtca agtgaaggtc cgatgtgttt ttgcaattca gtcatgaagc tttggcagaa
     9121 gcgcatgatt tcagcatcag tttttccttt aggatcaaag tctgaaccac ctttaccacc
     9181 gccgattgga agaccagtca agacgttttt gaagatttgc tcaaaaccga ggaacttcaa
     9241 gatggattgg tttacagttg ggtggaagcg aagaccgcct ttataaggac ctacagctga
     9301 gttgaactga acacggtagc cacggttgac ttgaacattt ccatctttat ctgtccatgg
     9361 aacacggaag ctgatgatac gctcaggctc aacgatacga gccaagatgt tttcttcgat
     9421 gtattctggg tgtgcttcaa aaacaggctc aagtgtagag aagagctctt ctacagcttg
     9481 gaggaattct gtttcatgtg ggttgcgggc tttgactgct tcaaaagaag cttggatgta
     9541 agctttggca tttgacatgg gatcacctga tttctttttt atttattaaa ttgtctgaca
     9601 atttaattta tctgataatt attatagcac catgattttt aaatgtaaag aagaaaatgt
     9661 aagaatttaa aaaaattaat aaatttttat tgcaaaatcc gaatgttagt agtaaatgaa
     9721 gaaaatccgt ttgtttctta tgatataatc aagaaagaat gacctatatg gaggataaga
     9781 tggtttcaac agtaacgaca ctcggtggat ttacctttga taattgtttg atgaatgcag
     9841 caggggtttg gtgcatgacc aaggaagaat tggatgcggt taagaactcg aaggcgggga
     9901 cttttgtaac aaaaacagca accttggact atcgcgcggg taatccagaa ccacgttatc
     9961 agaatgttcc gcttggttct atcaattcga tgggcttgcc aaatcagggc ttggcttact
    10021 atttggatta tctactagaa ttgcaggaaa cggagccaga acgcacattt gttttatctg
    10081 tagttggaat gtcgcctgat gagactcatg aaattttgag aactgtagaa gccagtgatt
    10141 ttaaggggct gacagagtta aatctttctt gtcccaatgt ccctggaaaa ccgcagattg
    10201 cctatgattt tgaaacgaca gaaaccatct tgcaggaggt cttcacttac tttaccaaac
    10261 cactcggtat taagttacca ccttatttcg atattgtgca ttttgaccaa gcagcagcga
    10321 ttttcaacca gtttcctttg aagtttgtca actgtgtcaa ttcgattgga aatggtcttt
    10381 atatcaagga tgagtcagtt gtcatcaagc ctaaaaatgg ttttggtggt atcggtggag
    10441 agtatatcaa gccgactgct cttgccaatg tccacgcttt ttaccaacgc ttgaaaccgg
    10501 agattcaaat tgttgggact ggtggcatct tgacaggtcg ggatgccttc gaacacattc
    10561 tctgtggtgc cagcatggtt caagttggaa caaccctgca aaaggaaggt gtggcagcct
    10621 ttggacgcat tacggctgaa ttgcaggcca tcatggctga aaaaggctac gagaccattg
    10681 aagattttcg tggcaagcta cagcaagatg actgagatca tctgttgaag acataaaaag
    10741 aagctaacat tgtactgttc tcccagatag tcttttaggg agtcgcgagg ggataatgtt
    10801 agctcttttt aaatggtctg tgaagatcgg tctgataatc gtttgaggaa tggaatacat
    10861 agtcagaaac atatatttgt gagatggaat tctgatttta tttagatttt ttagcaaaaa
    10921 tatcgtatac taatattaga acctctattt ataagtgatg tgcttttatg gaagaaatag
    10981 ttttttgagg gactgctgac tgtattttga acaaaggttc ttaagtaggg agtatgaggg
    11041 taaaggtatg gagagaaggg cgaactatat tcgcagaaaa cgatatgcgt cctatcggac
    11101 aaagatgcat ttgtttttta tttgtggctt agcgactatt atcttggcga ttattattgt
    11161 aagcgagcac ctagttccta ggctgaatca ggcctcagaa tcaatgcact cagataattc
    11221 tgttcgcatc atggctcatg gggatttgct ctatcacttg cctattcttc gaggagcaga
    11281 acagccagat ggaagttacg atttttctga gaattttacc tacgtaaagc cctggataga
    11341 acaggctgat ttcgctatcg cagactttga agggaccatt tctccagata tcgaattagc
    11401 aggttaccca ctttttaatg cgcctgccat tgtcgccaac aatatccatg atgcaggcta
    11461 cgatttggtg gacttagccc acaatcatat cttggactca catctatcag ggctgatttc
    11521 cactgtcaat acatttagag atgcaggtgt ggatacagtc ggtgtctacg ccgaaggcaa
    11581 tcgggcaact gcaccactct acattcggga agtcaatggt atccgtatag ctgtcctagc
    11641 ctatgcttac ggtttcaatg ggatggaggc tttgctgagt caggaggaat atgatgccta
    11701 tttatcggat tttgataaag aaaagatgcg ggcagagatt gagcgagctg agaaagaggc
    11761 agatattacc atcgtcatgc ctcagacggg tgtagaatac cagttggagc ctacggagga
    11821 acagaccagt ttgtaccatc aaatgattga ttggggagca gacatcgttc ttggtgggca
    11881 tccgcatgta gtcgagccga cggaaattct tgagaaagat ggtcagagaa aattaatcat
    11941 ctattctatg gggaattttc tatccaatca gcgtatcgaa agtatggaag ataccccaaa
    12001 tgcccagtgg acagaaagag gtgtcttgat ggaccttact attcagaaag agaatgggca
    12061 aacaagtatt caaacggctc aagcccatcc aacctgggtc aatcgccttt caaaagggac
    12121 ttattcaaca gatggatacg aacaattttc ctaccagact tacattttgg aagactgggt
    12181 cgctggtggt cgatactatg gacaattgga tctagataca caggcgcgtg tggatacagc
    12241 ctatcaagaa atgaaagact ttgtcaattt ggtatggtga ggagagagaa gatgatagtt
    12301 cgattaattg caacagacat ggatgggacc tttttagatg gtcaggggaa ttttgataga
    12361 gagcgatttt cacgggtctt ggatcaacta gatcagaaaa agattccttt tgttatcgct
    12421 agtggtaatg gaattgggcg attactacaa ttatgccaag gatttgaaga cagattaatc
    12481 tttgtagcgg ataatggagc ccatgtgtat caaaatggca agacagtaat tcgtcgggct
    12541 attcagcaag tggaagtcga agcaatactg cattttttca aaggccgttg ggcggatgta
    12601 tgtctgatgt tgtcgaacga tggaaatatt tatatgcagg ctggggcagg tatgccgttt
    12661 gcaggaactg atttgccaat agaactagct cagatggctg ccttccaaaa tcgtgtgaca
    12721 tatttagaca accttagtgc ctatccagtt tcagagtcaa tacacaaggt tggtctctgg
    12781 gttcctgaag cgcgtgtaga atcgataacg gaagccttta atcagggttt tcacggtcag
    12841 ttggtggctg taaccagtgg ttatggttcc gttgacattc taccgcaggg tatccataag
    12901 gcttggggct tggaacaggt tttgaccggt ctagatatcg aacctgaaca ggtaatggcc
    12961 ttcggtgatt cagacaatga tattgagtta ttgtcctatg ttgggtattc ctatgccatg
    13021 gaaaatgcga cagacaaggt caaggcggtt gccaaataca tggctccaag ccatttggaa
    13081 gctggtgtgc ttcaggtcat tgaagaatat atcttataag tatatagaaa aaagctagtg
    13141 ctctcaatcc agagaatgct agctctttta atttccaacg ctggtgaact tggtcatacc
    13201 atagcggaag aggttataat tgatggaaaa taggaccact accaccagag gcaacgccag
    13261 tccccacata gacaagtcta ggaagtagag agcagggaag taggcggtaa aggcgtaggg
    13321 gaaaacaaaa atcagcagga tttgaatgat ttttggatag atattgagtg ggtattgagc
    13381 catctgattg agggcgaaaa ttcccatagt caaaggaaat gattccacaa tccaaaatgc
    13441 tagagcagtt ggaccgagct gaatggctgc atagagtagg ccgatacaaa tggcaataaa
    13501 gattagtaag gctagttttc caagactcca ttccatgcct agctcatttg aagcttggac
    13561 tagtgcaagg gaaccgatga gggttgttcc gattccttgt ggctggattc gttcacagat
    13621 aagttgaaaa agtgggttca caggcatgag gaggaggcgt tcaaattcgc cttgtcggat
    13681 gtagcgactg ccaaacatcc agagattgtc aaagaatatc aggtgaatgg agcgtccgac
    13741 ggtcgctatt ccatagataa aaagcatttg accgtagttg aaaccagcga tttccttgat
    13801 atttccaaag agaatattga ggaaaatcag gtagacaatt tgttcaatca aagaggagaa
    13861 aagcccgatg aagaagtcca cccgaaagga catctgggcc atcatgtaga ccttgatgtt
    13921 atagagatag aggctgatat atttcttcat gttaacctcc aaaaatgaca atacgacgct
    13981 tggcttggga ccaaagagca gcaatgaagc aggctaggat gggtatccat ataacttgca
    14041 atcccaaagc agttagatcg ctttcctgtc ccaataaaat ggaaactgga acgttaaccg
    14101 cataattata gggaaggagc ttcaaaaagt tttccacagc ctgtggatag aagctgagtg
    14161 gcaaaagcgc tccagaagct agattgaaaa gtcccattct cagaagcatg actccccagg
    14221 cattgaccgt aaaaaatgct aagaagccaa aagccatatc cagtaattga acgataaaca
    14281 tccctaggat ggagctgact agaaagagca aaatagtttt tccgtcaggt agataaaaat
    14341 cctgatgaac aagtaagatg ccgataaata cgatagcaaa ttttatcagt tccaagagct
    14401 tatttccaag gtctttgaaa aagagagcta ggataaagga atagggtctg agaaattctc
    14461 cagcaatgct tccttttaaa atgctgtagg ataaatcttc tccgagtgag aaagaattta
    14521 aactggctag tagattagca aagatgatat atgtagtaaa ggtttgtagg gtaaagccat
    14581 tgacttctga ttgagtgaag aaaatggttt tccagacata gagagctacc aaaatcttca
    14641 ctgccagtga aacgaaggtc gctagaaaga aagccttata ctgcatagca ttcatcatgg
    14701 tcaggcgggt catgtagaga tatttacgca tggataccct cctcataaat ctgacggacc
    14761 atggtttcaa tttccaattc cttcatggtg acatcttcaa ttgaataatg attgaaaact
    14821 tgctcaatca cctgggcgct ggtccagacc ttgctttggt agtggatttc aaagtgaaaa
    14881 tcatctttac gaataaattc ccagccctcc aattgcaaat ctttttcaat tggtttttct
    14941 gtggagaaga gaatggtctt gactgtggaa aagcgttctt tgaggacggt cagtgaacca
    15001 tcgtagacct tcttgccctt atcaatgata aaaatccgct cacagaggct ctcgatgtcc
    15061 ttcatatcat gggaagtaat caaaaaggtg gtctggtatt cttgattcat atagcggatg
    15121 aaggagcgaa tggtctcctt gacgctggca tccaagccga tggttggttc gtccaaaaaa
    15181 acaacggcag gctggtggat aaagatagcc gcaaattcac agcgaactcg ttggccgagt
    15241 gacagattac ggattggttg cttcataata tcagccaagt ccaatagctc aatcaagaca
    15301 gccaatcgct ctttgaatac cttatctgga acatcataaa tttttgcgtg aaggataaaa
    15361 gattcttgga caggtaagtt ccaatccaag tgagattttt gtccaaagag aacgccgatt
    15421 tgcttattga cagctttgcg gttttcttgt ggattgagtc cgttgatacg aacctgtcct
    15481 tggtctggga agaggactcc agtaagcatt ttgatggtgg tggatttacc agaaccgttg
    15541 gagccgatat agccgatgat ttttcctttt cctacctgta aggaaatgtc ttgaacagca
    15601 gggattgact ttttctttgg cttgaaaaag gccttgatag agccttttag accgacttcc
    15661 ttatcaatga ttgaataggt ttttgaaaga tgttctgcct gaatcatatc ataatctcct
    15721 atttgaaaac gtttgcgtaa gataaggata ttataacata ttccccagaa agtggcggta
    15781 aaaagtcgcc tttaaggtaa catttttatt agaaaatcgg tcatatattg aggagattct
    15841 tgcttaccat ttttaatcca tacctgcatg ataccgaaga aggcatgtga aaaatagatg
    15901 ctgctgtatt ctttttccag ttgtgataaa ttctcttttc ctaagcgctc cgctaaatca
    15961 ttggcaacaa gaagtcggac tttattgata agaaaatttt ggatttcttg agttccgtta
    16021 tgggtcagta gggcagaaag caatttttca cgatagagca actcgaaaat ttctaaaaat
    16081 gatgattggc gattgccatc ataatggtca aatatagcct ctaatttgtg aaaaagtccc
    16141 tgttgatagg agtcgattaa ttcatattta tccttataat gggtataaaa actggaacga
    16201 ctgataccag cagtctgggc taggtgtgtt gttgtaatgt cattaaatcc ttgtgattcc
    16261 aggcaggtta ccatggcttc taaaattgcc tgtcgagttc gttctttccg actatctgtt
    16321 ctcataattt ctccttttga acatttttag acacagtgtc taaaaacagt tcttctgact
    16381 tgattttgaa attgatactt gtataatgta ttttatcagt ttttggacag tatgtctaaa
    16441 ggagttgctt atgttacaaa aagtaaagaa tattttcaaa aaaccaatga ccttgattac
    16501 cattctaggt attgcctgtg tcccagcttt gtataatatt agttttctaa cttctatgtg
    16561 ggatccatac ggccgactag accagctgcc tgtagcagtt gtcaatcaag accagtcggc
    16621 gagctttcaa gataaaaccc tcacaattgg tgatgatatg gtggacaata tgaaagagag
    16681 caaaagtctg gatttccact ttgtatcaga aaagaatgcg gagaaaggct tggaagaagg
    16741 ggactactat atggtcatca ctctaccaga agatttatca gaaaaagcaa ccagtctctt
    16801 gacgaatcag cctgaaccga taacgatttc ttatcaaacc tccaaaggtc atagctttgt
    16861 tgcttctaag atgggcgaat cagctatgga gaaattaaag acatctgttt cagagacaat
    16921 taccaaaacc tacacgactg ccgtttttga tagtatgaga gaaattcaaa ccggcatgat
    16981 cgaggcggca gatggtagcc aaaaattaac aaatggagct agtcaattgg agtcaggcag
    17041 ccaaacactt tcaaatggac tgactacttt aacgacttcg ggtcaagtac tcgtgacagg
    17101 agcaaaccaa ttggccaccg gagttgtgtc ttatacagat ggagtcaatc aggctgcaac
    17161 aggcagtcaa acactgtcca gtggcttaac gatttacaca aatggggtag cgagtcttgt
    17221 ttcaggtgcg gagcaattaa atgccaattc ctctcagctc atcactgggg tgggacaatt
    17281 gcaatcagga gcaagccagg ttgaacaact tgtaacggga gccaatcaat tgcaggcagg
    17341 cttggaacaa ctcgctaatt caactagttt gtctgctgaa cagtctagtc agatacaagc
    17401 actcttgaca gggcttccac agttgcaggt ggctatcaat caattaaatg acagcctatc
    17461 aagtatcgga ggacttgcag ttgataactc tactctatct agcctcttga cggagatggg
    17521 ggctcaggct caaggcttgt tgacagcagc ccaagctgat aaaacagcca gcatcgaagc
    17581 cttgcaaacc acggctacct atcaaaactt gacagctgat cagcaagctg aattggttgg
    17641 tgccctccaa aattcacctt cggcaacagc gacagtagcc caaacgattt tggatcaatt
    17701 gtctcagctc agtcaaaccc tttctagcct acaaagtctt tctggcatgg caacacaaat
    17761 gaaccagcta caatcagctg tcggtcagat taacacggct gccaatcaag cattgccagg
    17821 agctacaaca gccattgaaa gcctatcaag tggcttgagt caggtcaaca cagctttgaa
    17881 ccagcaagtt ctaccaggaa ctcaaacctt gacgagtggt gtgagtcaac ttcaaacgca
    17941 actgtcaagc ggagcgagtc aactcatgtt tggagtaaca gcctataccg caggtgttgc
    18001 tcaattagca gcaggtggag cccagttggt tgcgaataat agtagtatcc aatctggggg
    18061 tggccagcta acatcaggat tggcaacctt ggcatccaac tccagtcaac ttgtcagcgg
    18121 ttcagaacaa ctggcttctg gtagtcagca attaattgct ggtgcggatc aattagctag
    18181 tggtggccaa gccttgacaa gcggtatttc tagtcttcgt acaggtagtg agaccctaac
    18241 gaattcactc agctcagcca gtcaacaact atcagtcgtc tctgtagaag acaaaaatgc
    18301 acaagcagtt tctcaaccag tcaccttgga acacagtgac caagatgatg tgaagaccaa
    18361 cggtgtcgga atggctcctt acatggtatc agtcgcactg atggttgcag ccttatcagc
    18421 gaatgttatt tttgtcaaac acattgataa tcgctcctac aagaatcgtt gggactgggc
    18481 caaaggaaaa ctcttgctca atggtatcat tgccagccta gcagcagtga ttctgtacgg
    18541 tgttcttcgc ttgattggaa tcgaaccagc tcatccaatg gcaaccttgg gaataatcct
    18601 cttagcctct tggaccttca tggccctcgt tacagccttg gtgggctgga acaatcgttt
    18661 cggatccttc gcaagtttaa ttatcttgtt actacagctt ggatcaagcg caggtaccta
    18721 tccaattgaa ctcagcccac gcttcttcca agtcattcag ccctatcttc caatgaccta
    18781 ttctgtttca agtcttcgtc aaaccatttc tatggttgga aatagtagtc atcaagtttg
    18841 gatgctaagt ctcttcttag taggctttat gggactaggt ctcttgattt ataatcaaaa
    18901 agatgaataa gaataaaacc aactgctcca tgtgaacagt tggtttttgg ttgatgtggt
    18961 tatttggggg tccctaaatt gattgtcgca ttggtggctt caatggtcag tttgttcttg
    19021 ctacctttgt tttctagggt tagggtctgt agatcgtttt cagtcttgac agggaatttg
    19081 gtgtacttat cgctagtgaa aataccgact tcccctagtc gctcttttaa gtaagggtct
    19141 tggttaacca tctctcccaa atcattccca tcttcatagt agtaaccttg ggcttctact
    19201 aattttttct tgtcgatctg gttggtgatg agcaagttgc tatctgccag gctcttgtcc
    19261 gtcacatcca aaaatgtcgt agaggagtag gtgtcggatg gagtgaaacg attatcgcca
    19321 agaagagtcg tttgtctgct atccagctgg ctatagccct cgatggtcac attttccaaa
    19381 ctggtttcat acaggcggac gctgcttccc tgtaggttga tgtgcatatc ttttagagtg
    19441 gattgtgtcg cttggaagta gcctgcttca atctgaccgc tgtcaatagt caccttgtca
    19501 agagtgacac caccagacag atttgcctct ttgatatgga tattctcaat cgtgaaaccg
    19561 ccaaaatcat agaagtggag attgtgtccc tctaatttat ccagtgtctt ccctttaggc
    19621 acttcaatgg tgacggagaa gacattgata cgacgctggg ccaagctttc tcccagatac
    19681 tgcatgattc cctcaatggc aaattctagt tcctgtgcag agagggttaa gacgccgtct
    19741 ttctcactga gttttagagg gttttggata ttgttgtcgg agttggcata ggtcacatga
    19801 tagttgttat cactagactc tttgatgtag acgctgtggg ggataaaatc aattttaatg
    19861 gtattcaaat ctgtgaaggt cttatggact tccgtcggag cagcaacctc ttctaagcgg
    19921 gttatgcctc cggtgaaaaa tccaatgcca gctagaatta agcctgcaat caggctgaca
    19981 aagccgataa taatggcgat ggtaagtttc tttttcatgc tcgtttacct cgtttcaaaa
    20041 tccatttgaa gcaagccttg accagtcgcc aagaccagta ggcaaaaaat ccagtcaaga
    20101 tgtagatgag aatagctccg ccaatcaaag acaaacctga cccaaacccc atgaggaaga
    20161 tattgaaacc ttctgacata aggctaaagg cttcccaaat tagatagcca ccgctggtga
    20221 gaagtccgac acccaaaaca aaggcaccga caatgagggc caagatgagc gccaccaatc
    20281 ccaatagact agctaggaga atgagcaaaa gtggaatggc gataggcagg gaaatgacag
    20341 ctaggatagc caaccagagc gttcgttttg tttggctaaa attacggaag tagcgaccga
    20401 ggaaaaaagc gccgaggata agagtcgcaa acagaggaat gactccgata aactctccca
    20461 tgataaagag taggaagaaa gagaagagac ctgtcatact taaggctccc agaccaaccc
    20521 agagtttcca gttgagttga ataggttctt gttgatcctt ctcctcctgg atttgcttgt
    20581 tgagcatgtt gttaatgagt tcgctggcag cttcttttgg ggaaccaagt tcttctataa
    20641 tttctgtttc acgctctggt ccaacctcgt caaaatactc attaaagaag ctgatggctt
    20701 caaagtattc tttgtggggc agttttttga gatatttttc taactgctcc atatattcag
    20761 ttcttgtcat ggcggacgct cccttctatg atgccgttta tcgtgtttgt ataggtatcc
    20821 cagtcatctt tgagtcggac caattcttcg tgacctaact gagttaggct ataatacttt
    20881 cgcatacgac cctgatattc ttgggaataa gtagtcaaaa agtcattttg ctccaatcgt
    20941 tttaggatgg gatagagggc ggactccttg atgttggcaa ttaatttaat ggtctgacag
    21001 atttcatagc cataagaatc atcggattcc aaaatagcca tgatgagaaa ttctgtcagc
    21061 actgcgggga ctggaaaatg cataggacgc tcctttcctt tgttgttagt taggttcggt
    21121 tttgatatat agtgttcggt tgcatatatc aaatttttct atatattaaa tatacaccta
    21181 caaaaataaa ttgtcaagtg attatgtgca aaataaataa aataacttaa gaccaaatag
    21241 cttaggacaa atttttaagg tgtaaacgtt ttatagcctt gaaaaataat ttcagagtag
    21301 taaacttaat aacagtacta acattaaggg attttctgga ctaaaagaga atgacctcag
    21361 atggattagt agtatttaag gtggtgtaaa gatgaaacta tatgttcagt ttatgattat
    21421 tctggtattt tcatttttag gggaagctat ttcgactatt tttcatcttc ctattccggg
    21481 aagtattatt ggcttaatcc tcctattttt agccctagag ttcaaattga ttcgtcttcg
    21541 ccatattcat acggttggga attttttgct ggctaacatg accattcttt ttttgcctgc
    21601 agcagtgggc attatggaga gatttgatgc aattaaagat tatttacttc ctattatcgt
    21661 cgtcatttta ggcgccattt ttttaaatat cttagtaatt ggttttgttg ttcaatttgt
    21721 gaagcaaaag tttgaaggcg actacattga tgcggaggga aatcatgact gaactttttt
    21781 ccaatcctat ttttggtatt atgttatcaa ttgcagcata tttaattgga atgctgattt
    21841 atcggagatt tcctcatcca atcacaaccc cactgttggt agctacagga ttgattattg
    21901 tctttttaaa aatgacaggt atttcctata aggaatatta tgcaggaggg tcctatctaa
    21961 atatgcttat tgtgccttca acagtagctc tgggtattcc tttgtatcgt tctttccatc
    22021 taatgaaaca tcacattcga agtattcttt tgggaatttt tgttgcctgt attgtcaata
    22081 ctgtctttac tgccctaatt gcaaaatggt ttgggatgga tttttttcta gcaatctctc
    22141 tttttccaaa atcagtcacc actgctatgg ctgttggtat tactgataaa atgcaaggaa
    22201 tagcaacagt tactcttgta gtcgttgttg caacaggaat tctgacaagt gttcttggtc
    22261 cagtcttttt aaagctacta aaaattgaag acccggtagc tgttggtctt gctttgggag
    22321 gaacaggaca tgccattgga acgggtacag cgataaaatg tggacataca caaggagcga
    22381 tggctggctt ggctattggg attacaggca tcatgtatgt ggtgattagt ccaatagttg
    22441 cgcagattat cttacaataa aaaactacga ttggaattcc aaccgtagtt ttttagtcta
    22501 cataaagttt ggattgatta ttcaaccaac tataaagaag tccgataaag agaccgcctc
    22561 ccacgtagtt tcctaatcca gaaaagagga aattgcttag tacacttaat agagtcattc
    22621 cctcaactgg tccaccattt gcaaaaaagg ccagggagaa gagtgaaaag ttcgcaatga
    22681 cgtgctcata tcccaagaaa gcaaagataa agatgatgaa aataacggaa atgagacgtc
    22741 cagcgtcatc tttgatgcgt aagaaggtaa atacgccgat attcacgaca atattagcaa
    22801 aaattccttc aataaattga gtcaaaggtg tctttgaaag cttggccacc gttgcttcaa
    22861 ataggtagct gtgagcatca acgtgctgat aaggcagagt cagtgagacc aagtaacaaa
    22921 caaggacagc accgacaaag ttgaaaagga tacaggttgc caacatcttg agggctgttt
    22981 tagtaggaat cgtttttcga tggctggcta ctgtcatata catcatgttg gatgttccaa
    23041 gttcggcatt catatataaa atcatgagta gcccccaacc aaacatcaac ccatagctaa
    23101 atttcccgag tccttctgcg acatggttga gtttgtctgc tgtataaaga gaaatgacaa
    23161 tccccaatcc taaataaaga ctggctagta ttgatcgtac agcgtaggca gaaaaactgt
    23221 gttcaaacaa atctgctttt ttcttgatac tcttttcaag tgtatacatt aatgtctctt
    23281 ggttagctcc catcctaatc tccttactga atctactact ttttcgagta aacgttttct
    23341 ttttatcgaa tggctttact ttgtttatta tacttgataa aatggttgtt gtccaaaaaa
    23401 aattcaactt ttgaaaggaa atataagaaa aatatggatg ttacatggac agtgaaatat
    23461 atcactgaat ttttagcgac tgcactcctt attatcattg gtaatggtac agttgcaaac
    23521 gttgatttaa aaggcacaaa aggaaacaac tctggttgga ttctcattgc gattggctat
    23581 ggtttggcag ttatgatgcc agcattgatg tttggtaacg tttctggtaa ccatatcaac
    23641 ccagccttca cacttggttt ggctgtttca ggtctcttcc cttgggctca cgttgctcaa
    23701 tacattgttg cccaattgtt aggtgcaatg tttggtcagt tagtggttgt agcagtgtat
    23761 aaaccttact tcttgaaaac tgaaaattct aaccatattc ttggctcatt ctcaactatc
    23821 agtgcgcttg ataacggaac gaaagaaagc cgtaaagctg cgacaactaa tggtttcttg
    23881 aatgagttcg ttggttcatt tgtattgttc ttcggtgccc ttgctttgac caaacatttc
    23941 tttggttcag agttggttgg taaattgatt gaacagggct atgataaaac agtcgctgag
    24001 acaatgactg ctccatatac ttcaggttca attgcagttg cccacttagg cattggtttc
    24061 ctagttatgg ctcttgttgc cgctcttggt ggtccaacag gtcctggtct taacccagcg
    24121 cgtgaccttg gtccacgtat cgtccatgcc cttcttccaa aatctgttct tggtgaaaac
    24181 aaggctgatt caaaatggtg gtatgcttgg gttggtgtat gtgctccaat tatcgcatca
    24241 attgccgctg ttgcactttt caaattcttg tatctataat atagagaacc cgtttcgtcg
    24301 ggtttttctt tttctcttgg tatatcctat ataaagttgt ctgctctgct attttcctaa
    24361 aagttatgct acaataagga tagaaaaatc ggaaaagagg ctagaatatg tcagatgtta
    24421 ttgcttttgg ctatggaagc agtcgagcga agatgcagct caagcggctc aatcgtcatg
    24481 gaatcatcgc aggtgcgaca ggtacaggga agaccgtgac cttaaaggtc ttggcagagc
    24541 agttgagtga tgcgggaatt cccgtctttc tatcggacat caagggtgat ttgaatagtt
    24601 tggttgcggc caataccaag gagattgatc ctagtcgtct agagaagact cattatcttg
    24661 actatagccc agtcggttat ccagttgagt tgtgggatgt cttgggggaa aatgggactc
    24721 ctatccgcat gactatttca gagctgggac ctgtcctact gacacgtttg ttgggcttga
    24781 atgatactca ggagtccatc ctgaatattg ttttcagcgt ggcagacgag cgtggtctgc
    24841 tcttgattga tttgatggac ttgcgggcta tgttaaactt tgtggctgaa aatgcggcag
    24901 agctgagcca gtattatgga aatattccag ctcgttcggt cggtgctatc ttgcgtagtc
    24961 tggttgtttt ggagcaacaa ggtggtaaga ttttcttcgg tgagccaagc cttgatattg
    25021 ctgatttgat gcgtacggca gaagatggtc gtggtgttat taacgtcctt caagctactc
    25081 agctatttaa tcagccaaca ttatattcaa cggttcttct cagcctctta tcagaactct
    25141 atgaagtctt gcctgaggtg ggcgatttgg acaagcctaa gatggtcttc ttctttgacg
    25201 aggctcatgt tctcttcaaa gatgctccaa aagttcttct tgaaaagatt gaattgattg
    25261 tccgtttgat tcgttcaaaa ggtgtaggtg tcttctttgt aacgcagaat ccgacggata
    25321 ttcctgatag cgtggcagcc cagttgggta accgcatcca acatggtctt cgcgccttta
    25381 caccaaaaga gctcaagaca gttgctactg tcgctgaaac cttccgtcaa gaaggtgatg
    25441 aggatttggc caaggtcatt caggagttgc aagtggggga agctgttgtg tctacccttc
    25501 aagcagatgg tacaccaagc tttgcggatc gggttttgat ttatccacca aagagtatgc
    25561 tgggaacggt ggagccaagc gccctcttgt cagttatcaa taattctcct ttgatggaaa
    25621 aatatgctga cgcggtcaat cgtgaatcag cccatgagca gattttagcc atgacagagg
    25681 ctaaagaagc cgaactcatc aaaaaagcag agcaggccga ggcggaaaaa caggcagaaa
    25741 aagaagctaa ggcagccgca aaaatggaag agaaagccca gaaagaagca gctaaaactg
    25801 cacaaaaaac tagtcagcca gccagtcgca aaacagactc tatgatggat cgttttacca
    25861 agaacctgat gagtcaggtc ggacgggaag ttgggcgcgt ggtaactcgt ggcattatgg
    25921 gcatgttaaa agggaaataa acgactagac tgggaaggaa acttctcagt tttttatcta
    25981 gacaaagttc ttgccagatg ccacaaaatt cgttaaaata aacacaaatc actagttagt
    26041 aaggagttgc catgactgat caattgcagg cattattgaa agactatcag ccccagccat
    26101 tgggtgaaaa acgttcttat gcagttttct tgcccttagt ctggtcagac aatcagtggc
    26161 aggtcttata tgagattcgg agcgagtcca tttctcaacc gggagaagtt tcctttccag
    26221 gtggcggagt agaggtagga gaaacgccac agcaagcggc cgttcgggag gttatggagg
    26281 aactaaatat tcaacctgaa caaattgata tactcggaga aattgattat ttggttttgg
    26341 agtgctcaac cgttcattgc ttcgttggac ggttaaatct tgattggacg actatccttc
    26401 ctaatgaaga ggttgctcgg atatttacag tgcctctatc aactctatta acaactcagc
    26461 cagtctatta tcaactggat tcacagattg tcccagattg tgactttccc tttgaacgtt
    26521 tgagaggtgg ggttgactat cctttcagtc atcacaaacg ctcggttccc ttttatgaaa
    26581 atctatcaga aaatatctgg ggaatgaccg cccaatttac ccatcggttt acggaaatag
    26641 tgaaaagtaa tctatcgtga aatgataggt tatttttggg aggaaaaacc agcctttgcg
    26701 atatgtatca acgaaaaaaa tggagacaaa gctcaatgtg aaccaatgta tataaaaaca
    26761 caaaaaaaac agatgcatgg cagataaaag atagctatgg ctggtatact tggtacggtc
    26821 catattttga agtaccatca tctatccagg aatgcgacaa cattcatgta aacgcattca
    26881 gtgcttgttg tcatttccag taggtgagtg ggaaaatgta taaatctata ttttaagaag
    26941 gagccaatta tgagcaagca gaaagttgtg tccagtttat tattaagcac agtcgtatta
    27001 gggggattag ccttttattc aacgacaacg gttaaagcag aatcgctaga accagatgtt
    27061 acatcagtta atgcaagcga tgctactaat aaaccggtag taccaaatga agagggaggc
    27121 gactttttag ctgaagagga gcttgaagat gatgacactt tggaagaaga attaaatgag
    27181 aaagccgaag aggttactga gccatcttca cctgaagcac ttctccaacc tcgtgcgatg
    27241 atgagtgatt ctgaaactag tggtatggaa gaaattccga tgaatgatga accttcagat
    27301 aatacggaag aaaaggtaga gaagcaacag tcgccattaa ttcaaacctc aaatgcagat
    27361 tataaaagtg gtaaagatca agagaaactt aggacatcag tatctataaa tctgttgaag
    27421 gcggaagaag gtcagattca gtggaaagta acttttgata caagcgaatg gtcttttaat
    27481 gttaaacatg ggggtgttta ttttattctt ccaaatggtt tggacttaac aaagattgtt
    27541 gataataatc aacatgatat aacagcctcc ttccctacgg atattaatga ttacagaaat
    27601 tctggtcaag aaaaatatcg tttctttagt agtaaacaag gtcttgacaa cgaaaatggt
    27661 tttaattctc aatggaactg gtctgctggt caagctaatc ctagtgaaac agtaaacagt
    27721 tggaaatcag gcaatcgttt gtctaagatt tatttcataa atcaaataac agatactacc
    27781 gaattgacct atactttaac tgctaaggta actgaaccaa atcagcaatc attccctctt
    27841 ctggcagtga tgaagagctt tacgtataca aactctaaga gtacagaggt tacttcgcta
    27901 ggtgcacgtg agattaccct tgagaaagaa aaaactctac cacctaagga gaatccaaaa
    27961 ccagagccag aagctccaaa accagacgct ccacaagcgc catcagcacc ggaatctcca
    28021 acggaagaac ctaagaagga agacgctccg caaacaccac aagcgccatc gactccggaa
    28081 aaacaaccag aagtaccgga atcaccaaac ccagagacac cagacgcgcc atcgactcca
    28141 aaagatgaac cgcaggctcc atcaattcca gaagaaaaac cacaagtacc ggaagagcca
    28201 aaacaagagg ctccatcagc tccgtcaact ccggaaaaac aaccagaagc accggaatct
    28261 ccaacggaag aacctaagaa ggaagacgct ccagcgccat cgactccgga aaaacaacca
    28321 gaagtaccgg aatcaccaaa cccagagaca ccagacgcgc catcgactcc aaaagatgag
    28381 ccgcaagttc catcaatccc agaggagcaa ccaaaagaga ctccagcgcc agaagaacct
    28441 aagaaggaag atactccgca aacaccacaa gcgccatcaa ctcctaaaga ggaagcaccg
    28501 aaggaagaag ttccaacacc accggctcca tcagtaccag aagagcaacc aaaagaaact
    28561 ccaacaccag aagttccaaa acaagaagat gttcaaccgg aagcgccaaa atctgataaa
    28621 gtagaatctg acaaacaaat gccagaaact aagaaaccag atatgaagca accgaaggca
    28681 gacgacatgc ctaaggaaca aaagccgaaa gccgacgagc caaaggcaga gcaaccacaa
    28741 atggacaaac cacaaatgga agctcctaag aaagattcgg aagcgccaaa atctgataaa
    28801 gtagaaactg acaagcaatt gccagaaact aagcaaccag atatgaagca accgaaggca
    28861 gacgacatgc ctaaggaaca aaaaccgaaa gccgacgagc caaaggcaga gcaaccacaa
    28921 atggacaaac cacaaatgga agctcctaag aaagattcgg aagcaccaaa atctgataaa
    28981 gtagaaactg acaaaccaat gccagaaact aaacaaccag atatgaagca accgaaggca
    29041 gataaaccag aagcagagaa agctcaaatg ccacggacag agggtatgaa gcctgaatct
    29101 aaggcttcaa tgatgccaaa agcagaggca ccaaaagcaa ctttgccaaa tacaggcgaa
    29161 gcaagtagcg caataggctg gctaggtggt gctttagcca ctcttgccac aggcttgtat
    29221 ctattcaaaa acaaaaaaga agaatagtca ttattgaata agatataaga acttccctct
    29281 tctaagttca taaaagactc cagatcatcg ctgtagaagc cttggtttgg agtctttttg
    29341 ttaaatattc ttagaaaata acaaaataga taaatattag ataccctcta gaaaaaattt
    29401 agtttaggat gttatactaa cgctaaaaca ataatatcaa tttttgaaaa tactagattg
    29461 gaataaaaat ctaatcgcca tattttagaa cctgtactta caagtaaaga gcttttatgt
    29521 aagagatagt ttttcgctaa tcaagttaat tttttgaggg aatgctggct gtattttgaa
    29581 aaaacgaacg atgagtagct taaaaatgcc ttagatggga gtgctaacct gtaaatacag
    29641 gttcttagta aattgaagta aatagagtaa aggagcacat tatgagcaaa caaaaagttg
    29701 tgacaaatct attgcttagt acagctgtac taggtggttt tctaatatgt cacgcaccat
    29761 ctgtaagcgc agaaacaggc aatcttcaag aaatacctac tgaatctgct acggttagct
    29821 cagaaaatca aactgcgacc gcagtcgatg gaatttcacc tacggataac caattaccta
    29881 cgtcagaaga gggtgataaa caggctccag aagaaaaact agtttctagc gattctacga
    29941 gagaagaaag tgctacgcag gtagcgacag atccggatgc accatctcaa tcattaagtg
    30001 tgtcaggggc ggaaatttca acggcagatt caaatattca acaagccgaa gagaaactga
    30061 ttcaagaatc gaattattat agatttgaca cgcatcaagg tgaacagatt aggaaggcag
    30121 tatctataga aaaaatatcg gcagataatg acgaaattaa gtggaaagta acttttgata
    30181 gaaaaaattg gacctttagt ggagagggga gtggctatta ctttattctt ccaaaaggct
    30241 tacaattaac caaaattatt gatagccagt ctgaagagga tattttcaat aagttcccta
    30301 aggatgtcaa tagtgaggca aattctggcg ggcagccgta tcgctttttt agtagagaaa
    30361 aaaatgctaa taatgatgag cgtagttttg aaagtcagtg aggttggtct gttggacgtg
    30421 taggaggaga gctagaaaaa tggaaggaag aaagttccag catctatttt ctacaagtac
    30481 agcgagattc cgttgctaaa gaaaaagcga catatgaact gacggcacag gtgacaaatc
    30541 gagaaatgca gactttcccg gttttagctg tggtgaagaa ttttaaagag cgaatatttt
    30601 tctccagaga tgagattact tctgctgctg gtttgagatt aaaggtatcg gaaagtgcta
    30661 agccaaataa tgaagggatt actattatcg gagattcatc tccagaaagc gacaggactc
    30721 ctgaaccgcg gggagatagg actccggata tagatgtacc aaaggcagag gttccaaaag
    30781 ttgagcaacc aaaaccaaag gcccctgaag ttcaactgcc tgctcctaag gctccggaat
    30841 ctgtgccacc aaaagtaatg cctccagccc ccaaagttcc agacgttaag acgccaaaag
    30901 ttgagtaccc tgatacagat gctcctgaga ttgagtcacc aaaagctcct gaaactgaac
    30961 gaccagaagt cttaccaccg acgccaaaag tcccagaagt tgaggttccg aaagtaattc
    31021 caccgacctc aaaagttcca gaagctgagc taccgaaagt tgagcagcca aaaccgaagg
    31081 ttccagaagt tcaccttcct gctcctaagt ctccggaaac tgagccaccc aaagtaatgt
    31141 ccccagcccc caaagttcca gacgttaaga cgccaaaaga ggcgcctctg ccaccaaaaa
    31201 ctccgggcgt tgaggttccg aaagtaattc caccgacccc aaaagcccca gaagttgagg
    31261 ttccgaaagt aacaccaccg acctcgaaag ttccagaagt tgagacaccg aaagttgagc
    31321 agccaaaacc gaaggttcca gaagttcacc ttcctgctcc taagtctcca gaagttgagg
    31381 ttccgaaagt aacaccacca acctcaaaaa ttccagacgt taagacgcca aaatctccgg
    31441 aagttgcgca cccagaagtt gagaaacccg ccggaatcca accagaaaag ggtcaacctg
    31501 aggttaataa acccaatatt atccattcgg aggtgcttca atccgaagtt aagaaaacgg
    31561 aatctggagt ttcaatggct ccaaaggtag gaatacaaaa agagacttta ccaaatacgg
    31621 gtgaaacgag caacacccta gtatggctag gtggtgctct agctaccctt gcatcaagtt
    31681 tgtatctttt caaacaacac aggcaaagag aagaggaatg attttacgct aatgctatat
    31741 ttttggaacg ccaataaggc ttatctacca tggactaaga aaatttagaa cagttgtaaa
    31801 tagaaaacgt tccaaaatct gaactgcacc ccaaaagtta gaggtgaaat ctaatttttg
    31861 aggtgctttt cttgtaaggt caagacacaa agacaagatt gaaatttatc gtttgcaatg
    31921 atatgaagga gttggttata tattttgttt tatcaatact agtttgaatg ttattcgaga
    31981 atttgtagga cattctgagg atggtaagga gatagtgaaa atctatcttc atgtaataca
    32041 aaaa
//
LOCUS       DBNFCO010000014        32039 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.014, whole genome shotgun sequence.
ACCESSION   DBNFCO010000014 DBNFCO010000000
VERSION     DBNFCO010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 32039)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32039)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32039
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.014"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            92..1465
                     /gene="mnmE"
                     /locus_tag="AC1PIV_000565"
     CDS             92..1465
                     /gene="mnmE"
                     /locus_tag="AC1PIV_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HIP6611613.1"
                     /translation="MITKEFDTITAISTPLGEGAIGIVRLSGTDAFAIASTVFKGKDL
                     ATVPSHSLNYGHAIDPATGQVLDEVMIGAMRSPKTFTREDVIEINTHGGIAVTNEILQ
                     LLIRQGARMAEPGEFTKRAFLNGRVDLTQAEAVMDVIRAKTDKAMHNAVRQLDGSLSQ
                     LINDTRQEILNTLAQVEVNIDYPEYDDVEEATTELVREKTLQFQALLENLLRTARRGK
                     ILREGIATAIIGRPNVGKSSLLNNLLREEKAIVTDIAGTTRDVIEEYVNIKGVPLKLI
                     DTAGIRETDDIVEKIGVERSKKALEEADLILLVLNASEPLTEQDRNLLAISDMANRIV
                     LLNKTDLEEQIEVDQLPEDVIRISVLQNQNIDQIEEKINQLFFENAGLVEQDATYLSN
                     SRHISLIEQAVQSLHAVNDGLKVGMPVDLLQVDLTRCWQILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            1577..2653
                     /locus_tag="AC1PIV_000566"
     CDS             1577..2653
                     /locus_tag="AC1PIV_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611614.1"
                     /translation="MKKLLICIVLLSCLVFPFIGWKLYAYQHNTITLTSEADFYLIYP
                     GKVETFQLNGQEPQLLHTQKMNSQGYFGSGENYVIDNRYLVFANDQQKFINDNLISID
                     FNTGTVLRKPSQYSSYISGTDGQDFYTVGPYHILAQFDRNFDTIQTHVLNDDFIPSAP
                     VMVDQTSVYLTGFVKDFTQEGPEENVLIVFDKKDFSKQEVFKYDNTIATGEGLWVNGT
                     IYLPNLGKKTSEYTEIEQSSELLTFDTKTKTFSSVTLEHPSPSTLHALKDQKLLLIEH
                     QNGMFSPISFTIYNTQTGQESYHRLDELNPRPYYIDHVRQLDGNRLLLILAGKALIYD
                     WQAKKVLSQTILSEDYVSGVWVND"
     gene            complement(2775..3083)
                     /locus_tag="AC1PIV_000567"
     CDS             complement(2775..3083)
                     /locus_tag="AC1PIV_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009910392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611615.1"
                     /translation="MKMFRNSKKSKLFIQKINELLSDSELKLSKALKFQLLEAMELCE
                     KGSKISYLSYKIYPWVLEELALNRIQSDKLKMFKRYLEQERWKYYFGSALGMAFTSIR
                     "
     gene            complement(3166..4635)
                     /locus_tag="AC1PIV_000568"
     CDS             complement(3166..4635)
                     /locus_tag="AC1PIV_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0016600 - flotillin complex [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HIP6611616.1"
                     /translation="MDFGFDILAIMIPIIVVVLFVLLFVFGYVSAKPNEAIVITGLGK
                     PRTLIGRSGFMIPFIEKRSYISIEQFSTDVQTTDFVPTLDFINVKADAVVKVKVGVSD
                     ELLNAAAQNFLNWKTADISASIQDVLEGNLREIIGQMELRDMVNNRQAFAEKVQSNAA
                     PDLAKMGLEIIAFTVQSFTDDNDVIKNLGIDNIVTIQKDAANARAKAEREQAEVRARE
                     DKAANDARVAADLEIAKKQNELAIEQANLKRRSDVQLAQANAAYGIEEQAQRKEIERA
                     TAEANIVKQQKEAEVKAEEVKVREQELSATIRKQAEAEKYARQQAAEADLIERQRKAE
                     AELYETQREAEAQKARAEAAKYAAEQEAAGIEAKGRAEAEAIRLKLEAEAEGLSKKAD
                     AMAKFNDAAVTEMVVNVLPEIAKNIAAPLGNVDKITMYGEGNASKMVGDLMTTMDKTT
                     EGLGLNVRDLISATLTGRAMSTGLLTAQETKEVEGDKEK"
     gene            complement(4647..5228)
                     /locus_tag="AC1PIV_000569"
     CDS             complement(4647..5228)
                     /locus_tag="AC1PIV_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HIP6611617.1"
                     /translation="MKKRWLVILIPVLALLFLGMGAVGQYNGLVDSYAEVENAQANVD
                     TQLQRRYDLIPNVVAAVKGAMEHEEEIFTAIAEARAKIGSSQVGTSDYNQAQSQLDSA
                     VSRLLVVAENYPQLTANQQVSDLITELEGTENRILVARKDYNAVATTYNKKIKRFPTS
                     IYAGLFGYEKVELFQATNDAATTVPSVDLSDKE"
     gene            complement(5301..6077)
                     /locus_tag="AC1PIV_000570"
     CDS             complement(5301..6077)
                     /locus_tag="AC1PIV_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HIP6611618.1"
                     /translation="MRKWKKIIIGCFAILTVCLLFAPTLARANQIPDRPTGTTVVDET
                     QLLSSETIAEIDQLNRSWASTEQALQVGVYVTESLSSDIESLANETFRHWQVGFARTD
                     NGVLLVVAIADRAFRIETSDNAATVLTDVEAKDILENAREFFRQEDYSRGISYIVNSI
                     GDRFYGTSIGKNQLAAIEEGTSEKDDGFWLFLIVILIAILFGIIDKSSRGGGGPGNLL
                     WMLVDDHHHYHNHHSSNSSSSSFGGGSWSGGGGGGASSGW"
     gene            complement(6149..6727)
                     /locus_tag="AC1PIV_000571"
     CDS             complement(6149..6727)
                     /locus_tag="AC1PIV_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HIP6611619.1"
                     /translation="MELADIRQAIIEDVANRDFTNKGIAPLFQAPSTAKILIIGQAPG
                     LKTQEKGRLFDDASGSNLRQWLGVDRQTFYESGHFAILPMDFYYPGKGKSGDLPPRKD
                     FAPKWHPLIMKQLPQIELTILVGNYAQTYYLEKSQRNLTERVKHADDYLPTYFPLPHP
                     SPRNNIWQAKHPWFVEQTLPILKNNINILLGK"
     gene            complement(6714..7172)
                     /locus_tag="AC1PIV_000572"
     CDS             complement(6714..7172)
                     /locus_tag="AC1PIV_000572"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIP6611620.1"
                     /translation="MELKELYFSDMEMVKELFLSVFSQEPWNDDWSDEEQLDCYIGDL
                     LGHSRALCFGLFDQEKLIGLSLGYIRYWYEGTEYRIEEFCISRDYQGQGHGASLLADI
                     EKQLADRKIVHILLQTERNLLAYSFYKKCVFRALEEDVTIVKKVGHHGTC"
     gene            complement(7213..8613)
                     /gene="pepV"
                     /locus_tag="AC1PIV_000573"
     CDS             complement(7213..8613)
                     /gene="pepV"
                     /locus_tag="AC1PIV_000573"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HIP6611621.1"
                     /translation="MTVNFRAEFDKRKDEFLADLFDLLRINSERDDSQADAQHPFGPG
                     PVRALDKFLEIAQRDGYPTKNVDNYAGHFEFGEGDEVLGIFGHLDVVPAGSGWNTDPY
                     EPQIIDGKLFARGSSDDKGPTMACYYGLKIIKELGLSTSKKVRFIVGTDEESGWADMD
                     YYFEHVGLPLPDFGFSPDAEFPIINGEKGNITAYLHFAGENSGAAKLHSFTGGLRENM
                     VPESATAIISGDLADLDSKLVDFTAAYGIKADAETLENGQVQVTVIGKSAHGSTPEEG
                     VNGATYLAKFLSQFAFDEAAKAYLDLAGQVLLEDHDAKKLGVAIYDEQMGALSMNAGV
                     FKFDETSSDNTIALNFRYPKNTNPETIKAGLEKLGVEAVSLSEHGHTPHYCPIDDPMV
                     ATLLSVYEKHTGLKGHEQVIGGGTFGRLLKRGVAYGAMFPGDVNTMHQANEFIEVEQL
                     YRAAAIYAEAIYELIK"
     gene            complement(8714..9919)
                     /gene="sstT"
                     /locus_tag="AC1PIV_000574"
     CDS             complement(8714..9919)
                     /gene="sstT"
                     /locus_tag="AC1PIV_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0015826 - threonine transport [Evidence
                     IEA];
                     GO_process: GO:0032329 - serine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HIP6611622.1"
                     /translation="MNKIISVWKKMNLIRKIGIGVVLGVLLGLIAPKITVIALFGSLF
                     VGALKAIAPLLVLTLVAHALSQAPAGQKSNMRTVICLYLFGTFAAAFIAVGASYLFPI
                     KLVLSTTTTTDITPPQGIAEVFQDLLLKVVDNPINALATANYIGVLTWAAVFGLAFRH
                     ASKTTKDLLQSTAEVISKVVGWIIGLAPFGIMGLVFDTIANNGLTALKDYGLLLLLLV
                     GSMIFVALVVNPLIAFLVMKKNPYPLVFECLRVSGVTAFFTRSSAANIPVNMQLCKRL
                     GVDPDTYSVSIPLGATINMAGAAITINILTMAAVHTLGISVDFSSALLLSVVASLSAA
                     GASGVAGGSLLLIPVACSLFGIPNELAMQVVGVGFVVGVIQDSCETALNSSTDVLFTV
                     VAERSAWKK"
     gene            complement(10290..10658)
                     /locus_tag="AC1PIV_000575"
     CDS             complement(10290..10658)
                     /locus_tag="AC1PIV_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611623.1"
                     /translation="MKITTPSRKTQTANTANARLGIYRNTYDLVGRQFLMVSNSINLY
                     GRWEYEYGTITEVRYDGLLQTNITGVKGQSGSPVVVDGRIIGVVSNIDSNSKIVITPL
                     TTEMKTQLFDKNGIKNIDIY"
     gene            complement(10698..10835)
                     /locus_tag="AC1PIV_000576"
     CDS             complement(10698..10835)
                     /locus_tag="AC1PIV_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611624.1"
                     /translation="MADDGTGRVTSQTWSGNAVWGDASPYYELSEIKRTNPFNPFIQM
                     P"
     gene            complement(10871..11068)
                     /locus_tag="AC1PIV_000577"
     CDS             complement(10871..11068)
                     /locus_tag="AC1PIV_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611625.1"
                     /translation="MKTKLLLGVALLSVGLSVAPPTIVEVEAQTTHVSDPALRNSYPY
                     NLSHYLEVNVGSGQTKKVQLF"
     gene            complement(11246..12022)
                     /locus_tag="AC1PIV_000578"
     CDS             complement(11246..12022)
                     /locus_tag="AC1PIV_000578"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HIP6611626.1"
                     /translation="MTDYVNYNQERWNRVSARQGNAYTVPLSHEEFLVAKDKPLSVSL
                     TVGKTVPLDWFEKAKGKKLLGLACGGGQQGPISAAHSYETTILDFSKEQLDKDRLVAE
                     RENLDLQTVQADMTQAFPFEDESFDIIFCPVSNIYIEDLANMWQESYRVLKKGGLLMV
                     GYMNPWIYVFDADDVWEHPDKTLVPKYSLPFNARQLEEAGQITIDPEYGYEFSHTLEE
                     QIAGQLRAGFAMIDFYESKDSRNRLTQFASDYLANLSIKW"
     gene            complement(12153..13697)
                     /locus_tag="AC1PIV_000579"
     CDS             complement(12153..13697)
                     /locus_tag="AC1PIV_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000025412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HIP6611627.1"
                     /translation="MSILEVKNLSHGFGDRAIFENVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGQLQPDEGKVEWSRYVTAGYLDQHAKLEKGQSVRDVLRTAFDELFKTEARIN
                     DIYMSMAEEGADMDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDYGMDKDVT
                     ELSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQLLTRYTGDYYQFQEVHAMKRAQLEAAYERQQKEIADLQDFVN
                     RNKARVATRNMAMSRQKKLDKMEIIELQAEKPKPSFDFKMARTPSRFIFQTTDLEIGY
                     DRVLTRKPLNLTFERNQKIAIVGANGIGKSTLLKSLLGIIPPLGGSVERGEYLELGYF
                     EQEVAGGNRQTPLEVVWDAFPALNQAEVRAALARCGLTSKHIESQIQVLSGGEQAKVR
                     FCLLMNRENNVLVLDEPTNHLDVDAKDELKRALQAYKGSILMVCHEPDFYEGWVDDVW
                     DFNDLT"
     gene            complement(13861..15210)
                     /gene="glmM"
                     /locus_tag="AC1PIV_000580"
     CDS             complement(13861..15210)
                     /gene="glmM"
                     /locus_tag="AC1PIV_000580"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HIP6611628.1"
                     /translation="MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETDVPRV
                     FVARDTRISGQMLEAALIAGLLSVGIHVYKLGVLATPGVAHLVKTEKASAGVMISASH
                     NPAQDNGIKFFAGDGFKLDDALEAEIEALLDAEEDTLPRPSAQGLGDVVEYPEGLRKY
                     QQFLVSTGTDLDGMKVALDTANGAAATSARQIFVDLGADLTVMAEKPDGLNINEGVGS
                     THPEKLQELVKETGSQIGLAFDGDSDRLIAVDENGVLVDGDRIMYIVGKYLADRGLLA
                     KNTIVTTVMSNLGFHKALDREGIEKAVTAVGDRYVVEEMRKEGYNVGGEQSGHVILMD
                     YNTTGDGQLTAVQLTKIMKETGKKLSELAAEVTIYPQKLVNIRVENSMKDKAMEVPAI
                     AAIIEKMEAEMAGNGRILVRPSGTEPLLRVMAEAPTDAEVDYYVDTIADVVRAEIGS"
     gene            complement(15223..15927)
                     /locus_tag="AC1PIV_000581"
     CDS             complement(15223..15927)
                     /locus_tag="AC1PIV_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CdaR family protein"
                     /protein_id="HIP6611629.1"
                     /translation="MNDKFKAVGHLALSIFLALLLFFYATTTNYKNSESAAQNTESET
                     YVHTLSNVPIEIEYDTNKYFISGFSSTVAVELRGSNRVLLQRESDESTRTFQVTADLR
                     ELSDGTQTVKLQLTNLPAGVSATLAPDAITVKIGKKVSKAFPVAGRVYSNQLAEGYSL
                     SKVSVNVDTVKVTTDEETMAKIDRVEAVAMDVSNLSENYSGTAKLQAVDSDGNVLPVV
                     LSQTEANMQIILTKTK"
     gene            complement(15920..16771)
                     /gene="cdaA"
                     /locus_tag="AC1PIV_000582"
     CDS             complement(15920..16771)
                     /gene="cdaA"
                     /locus_tag="AC1PIV_000582"
                     /EC_number="2.7.7.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004016 - adenylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0006171 - cAMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diadenylate cyclase CdaA"
                     /protein_id="HIP6611630.1"
                     /translation="MLNLNQLLDTGYWSSLIASPWTALLHLIDISIVVYLIYNFSKSI
                     AGTKIMTLIRGVFLFIIVQIIASLFGLQTIAWLINQVITYGVIAAVVIFAPELRAMLE
                     KLGRTTQIFGTNTVSAEEKLIVAFLKSVAYMSPRKIGALVAVEQAQTLQEYRATGIPL
                     NADISQELLINIFIPNTPLHDGAVIVKEDKVAVACAYLPLSESAGISKEFGTRHRAAI
                     GLSEVSDAFVFIVSEETGSISIARNGIFKHDLTLDEFEAELRATFISENVEKKSIWKR
                     LGGGKHE"
     gene            16953..18296
                     /gene="murT"
                     /locus_tag="AC1PIV_000583"
     CDS             16953..18296
                     /gene="murT"
                     /locus_tag="AC1PIV_000583"
                     /EC_number="6.3.5.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016881 - acid-amino acid ligase activity
                     [Evidence IEA];
                     GO_function: GO:0140282 - carbon-nitrogen ligase activity
                     on lipid II [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II isoglutaminyl synthase subunit MurT"
                     /protein_id="HIP6611631.1"
                     /translation="MKINTALGILAGKSSQFILKKLGRGTTLPGKIALKFDKHILDSL
                     AKDYEVVVVTGTNGKTLTTALTVGILQEAFGEITTNTSGANMITGITATFLSAKKNKN
                     GKKIAVLEIDEASLARVTDFIKPSLIVFTNIFRDQMDRYGEIYTTYQMILDGAAKAPQ
                     ATILANGDSPLFNSTNVINPVKYYGFATEEHEPRLAHYNTEGVLCPHCHQIIQYKLNT
                     YANLGSYICTNCGFSRPELDYKLTKLKEITNTSSTFVIDGQDYKINIGGLYNIYNALA
                     AVSVAEFFGVSPEKIKAGFDKSKAVFGRQETFKLGDKDCTLVLIKNPVGATQAIEMMK
                     LAPYDFSLSVLLNANYADGIDTSWIWDADFEQITQMDIPQVFAGGVRSSEIARRLRVT
                     GYPENQITETPKLEDIMTLIEQSSSQHAYILATYTAMLEFRDLLAQRQAVGKEMK"
     gene            18296..19084
                     /gene="gatD"
                     /locus_tag="AC1PIV_000584"
     CDS             18296..19084
                     /gene="gatD"
                     /locus_tag="AC1PIV_000584"
                     /EC_number="6.3.5.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0140282 - carbon-nitrogen ligase activity
                     on lipid II [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II isoglutaminyl synthase subunit GatD"
                     /protein_id="HIP6611632.1"
                     /translation="MVYTSLKSPEKDYTYDLHIAHLYGDLMNTYGDNGNILMLKYVAE
                     KLGARVQVDIVSLTDEFDKNFYDIAFFGGGQDYEQSILAKDLPTKKDSLADFIENDGV
                     MLAICGGFQLLGQYYIEAGGRKIDGLGIMGHYTLNQTNNRYIGDIKIHNDEFNETYYG
                     FENHQGRTFLADNQKPLGKVVYGNGNNKEDGGEGLHYKNTFGSYFHGPILSRNANLAY
                     RLVTTALRKKYGQDIQLASYADILSKEVAEEYGDVKSKAEFDTQ"
     gene            complement(19224..20051)
                     /locus_tag="AC1PIV_000585"
     CDS             complement(19224..20051)
                     /locus_tag="AC1PIV_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative RNA methyltransferase"
                     /protein_id="HIP6611633.1"
                     /translation="MTKHQRFANSDQFFACPHCGQALGLDLNSLRCPNRHTFDIAKQG
                     YVNLAPQVKQSANYHKSSFENRQAFLEAGYYDHLYEALEEKIAELGLRSVLDIGCGEG
                     FYSRKLAEKMDLDILAFDISKDSILLAARTDRTKSVKWFVGDLTKLPIQDKTIDGILD
                     IFSPANYQEFARVLKAGGAILKLVPGPNHLKELRHLAKDQLRKESYDNQDIVDHFKSY
                     MGQVEQEVVSRTLPIGIEQARILADMTPLFFQVDQSKLDLSQLTEITVEGLLLIGSI"
     gene            complement(20053..20529)
                     /locus_tag="AC1PIV_000586"
     CDS             complement(20053..20529)
                     /locus_tag="AC1PIV_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIP6611634.1"
                     /translation="MNFGQQIKDLRKKKGLTQEQFALKLNVTRQAVSNWENDKNLPDL
                     ELLILMSSVFSISLDQLILGGTDMNNMTEKLVKDGREGRRTQMHLTITIIGSFLMLLG
                     FVCFVIKANSVEYIDAEGILHENFYLIPVGYLLVFTGALATLLSGLALHRFRKEHK"
     gene            complement(20967..22865)
                     /locus_tag="AC1PIV_000587"
     CDS             complement(20967..22865)
                     /locus_tag="AC1PIV_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HIP6611635.1"
                     /translation="MIILSGNKIERSFAGEVLFNNINIQVDERDRIALVGKNGAGKST
                     LLKILVGEEAATSGEISTKRDLSLSYLAQDSCFESENTIYDEMLHVFDDLRMTEKRLR
                     SMEEQMGSLSGNELDQLMKTYDSLSEEFRLAGGFSYEADIRAILNGFKFDQTMWDMKI
                     SELSGGQNTRLALAKMLLESPELLVLDEPTNHLDIDTIAWLENYLVHYKGALIIVSHD
                     RYFLDKVATLTLDLTKHSLDRYVGNYSQFVELKEQKLQTELQNYEKQQKEIAKLEDFV
                     QKNIVRASTTKRAQARRKQLEKMDRLDKPTTGQKSANMTFQSDKTSGNIVLTVENAAV
                     GYDGNILSQPISIDQRKLDAIAIVGPNGIGKTTLLKSIVGALPFIKGEAWLGANVEVG
                     YYDQTQSALTPSNTVLEELWSAFPTTPEVEIRNRLGAFLFSGDDVKKSVSMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     KVLEISETGSTLYLGDYDYYLEKKAELEAEAQPDQLESTSQSAGAMDYQAQKENQKEQ
                     RKLARRIEQIEAEIDSIENRLNELNQAMLETNDIGQLTDYQKEIDQLTSQQESLMEEW
                     EELSEQMG"
     gene            complement(22966..23331)
                     /locus_tag="AC1PIV_000588"
     CDS             complement(22966..23331)
                     /locus_tag="AC1PIV_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611636.1"
                     /translation="MLRTITNTIKRYPEQALLFLYNAGIFAWMQSTSHSIMEQIGIDS
                     NWFDKIPEPIKAWTGASLESMQTLLNSSAWGWLIVSMILMLVIRFVKGLIKFVIMLII
                     IGGGLYLLWQNKELLSGLV"
     gene            complement(23342..24001)
                     /locus_tag="AC1PIV_000589"
     CDS             complement(23342..24001)
                     /locus_tag="AC1PIV_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M57 family metalloprotease"
                     /protein_id="HIP6611637.1"
                     /translation="MKLIGNILRWIWRTFWGLIWLSMVLLACGLGLLFYFQQEAAPQM
                     LQTLPQEVQLMVKGQSEVTTDTVNTADHGRWESNTATVYIETQNPTFVAAYETAIANW
                     NATGAFTFVMTSDPNQADIIATEMNDGNTQAAGEANSTTNLLTNYYSSVTVCLNSFYL
                     LNDQYGYDMDRIIHTAEHELGHAIGLDHEDSQTSVMESAGSNHGIQQADIDAVLALYS
                     E"
     gene            complement(24067..24843)
                     /locus_tag="AC1PIV_000590"
     CDS             complement(24067..24843)
                     /locus_tag="AC1PIV_000590"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HIP6611638.1"
                     /translation="MAIMKIEYHSEALDMSRQVTVLYPDRNRVENPDDNDIPVLYLLH
                     GMGGNQDSWLNRSTIERLVRYTNLIVVMVNTDKAWYTNTTYGMNYYDAIAIELPQILK
                     RFFPNMSDKREKNFIAGLSMGGYGTFKIAMMTNRFSHAASLSGALYFDFDNPAAAELG
                     SLSYWQGVFGDISDKQNPNNLLEIAKQSDKKTKFYAWCGEEDFLFEGHQKAVEELKEL
                     GFDIEASFGPGKHEWYYWNQQIEKVLAWLPIDFKLEERLS"
     gene            complement(24908..26569)
                     /locus_tag="AC1PIV_000591"
     CDS             complement(24908..26569)
                     /locus_tag="AC1PIV_000591"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004521 - RNA endonuclease activity
                     [Evidence IEA];
                     GO_function: GO:0004534 - 5'-3' RNA exonuclease activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HIP6611639.1"
                     /translation="MSTIKIMALGGVRENGKNLYIAEVNEHIFVLDAGAKYPENEQLG
                     VDVVVPNFDYLEENKHRVAGVFLSHGHADAIGALPYLLEKVKVPVFGSHLTIELAKLL
                     VKGNNATKKFNDFHVINAETEIDFGDSVVSFFQTTHSIPESLGIVVKTDEGNIVYTGD
                     FKFDQAADKFYRTDFGRLAEIGNEGVLALLSDSANADSNVQVASMHEAGEEILNTIAD
                     CDGRVIVAAVASNIVRIQQIFDAAEATGRRVVLTGHDVENIVRTAIQLKKLRLVSERL
                     LVKPKDMNKYEDHELIILETGRMGEPLNGLRKMSIGRHRYVEIKEGDLVYIVTTPSIS
                     KEAVVARVENLIYKAGGTVKSITKNLRVSGHGNARDLQLMLNIMKPKYLFPVQGEYRQ
                     LDAHAKAALEIGMYPENIIIVKRGDVMAFEEGDFVHSGAVPAGDVMIDGNAMGDVGNI
                     VLRDRKILSEDGIFIVAITVNRREKKIISKAKVNTRGFVYVKKSKDILREASELVNTT
                     VENYFTKDSFDWAELKSAVRDDLAKFLFDQTKRRPAILPVIMEVK"
     gene            complement(26959..27363)
                     /locus_tag="AC1PIV_000592"
     CDS             complement(26959..27363)
                     /locus_tag="AC1PIV_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HIP6611640.1"
                     /translation="MRKCLAICSLLCCLFLVGCRTGAAYQAEIEPMEQSELYTEKEIE
                     AAILVVQDYFDHHFNSCKLLTIGYSGDNEKEFDEWAEHYGAEEAIILTSSFKVAAEGA
                     EPTLEPNSTHTDWKWILVRNVGGKWEHKGHGY"
     gene            complement(27369..27854)
                     /locus_tag="AC1PIV_000593"
     CDS             complement(27369..27854)
                     /locus_tag="AC1PIV_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HIP6611641.1"
                     /translation="MDKLVFESLADLGMDYTIVEHPPALTTEEADRYIEGVEGVRTKS
                     MFLTNKKKTAFYLLIMDDQKQLDMDQFRDLVGANRIRMASSDSLMEKMHLPAGAVSVF
                     GLLHNVDKDIQVFFDKEILSEPILTFHPNVNTKTIFVKTEDVLRFVEEIGFSATIVDW
                     G"
     gene            complement(28037..28795)
                     /locus_tag="AC1PIV_000594"
     CDS             complement(28037..28795)
                     /locus_tag="AC1PIV_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIP6611642.1"
                     /translation="MKAIVELKNATKVVTNGFDEERVILDNVNLTIYQGDFITILGGN
                     GAGKSTLFNVIAGTLPLTSGSVHILGEDVTNWPAEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKYRGEGRGLLPRRLAQQTEEFAQLLPRVGNGLEKHLDTPAGLLSGGQRQAL
                     SLLMASLKQPELLLLDEHTAALDPKTSQSLMQLTDELIETKGMTALMVTHQMEDALRH
                     GNRLIVMKNGQIIQDQTAEEKSKMKLEDYYKLFD"
     gene            complement(28792..29658)
                     /locus_tag="AC1PIV_000595"
     CDS             complement(28792..29658)
                     /locus_tag="AC1PIV_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002902146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIP6611643.1"
                     /translation="MIVSTVSQALLWAVLGLGIFVTFRILNFPDMTTEGSFPLGGAVA
                     VTLLTQGVHPILATLAAVLVGCLAGFVTGLLYTKGKIPTLLAGILVMSSCHSVILFIM
                     GRANLGLLNTKRLQDFLPFSEQVNGLLLGLGSLAVVIGALMFFLYTRLGQAFIATGDN
                     PDMARSFGINTSRMELLGLVLSNGIIALAGALIAQQEGYADVSRGIGVIVVGMASLII
                     GEVIYGNLTMLERFLAIVVGAIFYQFLILVVISLGINTSYLRIFSAMILATCLMVPEL
                     KNKLLKGASLSR"
     gene            complement(29681..30682)
                     /gene="trpX"
                     /locus_tag="AC1PIV_000596"
     CDS             complement(29681..30682)
                     /gene="trpX"
                     /locus_tag="AC1PIV_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan ABC transporter substrate-binding
                     protein"
                     /protein_id="HIP6611644.1"
                     /translation="MLKNKNLLATIVALTVMVVAALFMTQKEQNNSSTSTEKVKIGVL
                     QFVTHDSLDEIYKGIKAGLEEGGYTTTDNLEIDFMNAEGDQSQVQTMSKKLVDNGNEL
                     LIGIATPAAQGLANATTELPIIMGAVTDPVGANLVTDLKNPGGNITGVSDQTPVADAV
                     SLIKEITPDAKTIGVLYSSNEDNSKIQVAEFKAAAEEAGYTVLEYAVASSNEIAATVE
                     VASSKADVLFTPVDNTVASAFSTVVSVANKTKTPIFTSVEDMVEGGGIASVTLSQYDL
                     GVATGKMAAKILDGANPADTPVQIFNEGTVVVNQKVAKELGITLSDDVISKASKVIE"
     gene            complement(31439..>32039)
                     /locus_tag="AC1PIV_000597"
     CDS             complement(31439..>32039)
                     /locus_tag="AC1PIV_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HIP6611645.1"
                     /translation="NGIKITFVEGDEELLKNNTVDFLSFSYYMSITQAADPSKYSSGK
                     GNILGGLVNPYLEASDWGWQIDPIGLRLTLNRYYNRYQIPLFIVENGLGAKDQLVKDE
                     AGGLTVHDDYRIQYMQEHLLQVAEAIQDGVEVMGYTSWGCIDCVSMSTAQLSKRYGLI
                     YVDRNDDGSGSLTRYRKKSFYWYKEVIQSNGSILSNSSK"
BASE COUNT         9041 a         7649 c         6205 g         9144 t
ORIGIN      
        1 taaatatatt tacatcccca tccctcatct gtgctttttt catcattcca tgatacacta
       61 atagataaga caattttaga aagaaagata tatgattacc aaagaattcg acaccattac
      121 cgctatttcc acccctctcg gtgagggcgc tatcgggatt gtccgcctat ctgggacgga
      181 cgcttttgcc attgccagca cggttttcaa gggcaaggac ttggcgactg tacccagcca
      241 cagcctcaac tacggtcatg ccattgatcc tgcaacgggt caagtgctgg acgaggttat
      301 gattggagcc atgcgttctc caaagacctt cacccgcgaa gatgtcatcg agattaacac
      361 ccacggaggc atcgccgtta ccaacgaaat cctccagctc ctcattcgcc aaggggctcg
      421 aatggctgag ccgggtgaat ttaccaagcg ggcctttctc aatggtcgtg tggatttgac
      481 ccaggccgaa gccgtcatgg atgttatccg cgctaagacc gacaaggcca tgcataatgc
      541 cgtccgccag cttgacggct ccctctccca gctcatcaac gacacgcgcc aggagattct
      601 caacacactg gctcaggtcg aggtcaacat cgactacccc gagtacgacg acgtcgagga
      661 ggcgacgaca gagctggtcc gtgagaagac cctccagttc caagctcttt tggaaaatct
      721 cctccgcact gcccgccgtg gaaaaatcct gcgtgaaggc atcgcaaccg ctattatcgg
      781 tcgtccaaat gtgggaaaat ccagcctgct caataacctc ctccgcgagg aaaaagccat
      841 cgttacagac atcgcaggaa caacccgtga cgttatcgaa gaatacgtca acatcaaggg
      901 cgtccccctc aagctgattg atacagcagg tatccgtgaa acagacgaca tcgttgaaaa
      961 aattggtgtg gaacggtcca aaaaagctct tgaggaggcc gacctgatcc tgctagtcct
     1021 caacgcatct gagcccctga ccgagcaaga ccgcaatctc ctagccattt ccgatatggc
     1081 caaccgcatc gtcctgctca acaagaccga cctggaagag cagattgaag tagaccaact
     1141 gcctgaggat gtcattcgca tttccgtctt gcaaaaccag aacatcgatc agattgaaga
     1201 aaaaatcaat caactcttct ttgaaaatgc tggtctggta gagcaagatg ccacctacct
     1261 ctccaattct cgtcatattt ccctcattga gcaagccgtt caaagcctac atgctgtcaa
     1321 tgacggactg aaagtgggca tgccagtaga cttgttacag gttgacctga cacgctgttg
     1381 gcaaattttg ggagaaataa caggtgatgc tgctccagat gaactcatta cccaactctt
     1441 tagccaattc tgtcttggaa aataagaaca aaagtcatgt aagaaaactt gcatgacttt
     1501 atttgtatat taacacataa tttcttgtct aagatgacaa atttagatat actaaacagt
     1561 gaaaggcggc attcccatga aaaaacttct tatttgtatt gtccttctat cctgtcttgt
     1621 ctttccattt atcggctgga aactatatgc ctatcagcac aatacgatca cattaacgtc
     1681 ggaagctgat ttttacttga tttatcctgg caaggtcgag acttttcagc taaatgggca
     1741 agagcctcaa ctccttcata cacagaaaat gaattctcaa gggtattttg gctctggtga
     1801 aaattatgtc atagacaatc ggtatctagt ctttgccaac gatcagcaaa aattcattaa
     1861 cgacaatctg atatccatcg atttcaatac tggcactgtc ttgcgaaagc caagtcagta
     1921 tagtagctat atcagtggta cagatggaca agacttttat acagtggggc cctatcacat
     1981 actagcgcaa tttgacagga attttgatac tattcaaacc cacgttttaa acgatgactt
     2041 catcccaagt gctccagtca tggtagacca aacgtcagtc tatttaactg gttttgtgaa
     2101 agattttacc caagaaggac ccgaagaaaa tgtcttgatt gtatttgata agaaagattt
     2161 ttcaaaacaa gaggtattca agtacgacaa taccattgcc acaggagaag ggctttgggt
     2221 caatggaacc atctatctcc caaatttagg gaaaaaaaca agtgagtata cggaaattga
     2281 acagtcatcc gaactcctaa cctttgatac aaaaacaaaa acattttcgt cagtaacttt
     2341 agaacacccc tcaccaagca cactacatgc tctcaaagac cagaagcttc tcctcatcga
     2401 acatcaaaat ggtatgttta gcccgatctc atttaccatt tataataccc aaacaggtca
     2461 agagagctac catcgtctag acgagcttaa tcctcgtcct tattatattg accatgtccg
     2521 ccaactagac ggtaacagat tattattgat tctggctggt aaggcactca tctatgactg
     2581 gcaagcaaaa aaagttttaa gccaaactat tctatctgag gattatgtta gcggggtgtg
     2641 ggtaaatgac tgataaacaa aaacgaatct caataaagat tgtaaaagtc ccaagatgac
     2701 tctttcttgg gactttcgca tattctatcg aagttgcaca gcacaatcaa tgtacttata
     2761 aatcctagga accactatct aatcgaagta aacgccattc ccaaagcaga accaaaataa
     2821 tatttccacc tttcttgctc taaatagcgc ttaaacatct ttaatttatc cgattgaatc
     2881 ctattcaaag ctagttcttc caatacccat ggataaattt tatacgaaag atagctaatc
     2941 ttactacctt tttcacacaa ctccattgct tccaacaact ggaatttcaa tgctttgctc
     3001 aactttaatt ctgaatcaga taatagttca tttatttttt gtataaacaa cttacttttt
     3061 ttactgtttc taaacatttt catcttcgta gggatttctg aaacaatcat gcgatggaaa
     3121 tgatggtgca aacctactca gtcacccatc tcttccaact gcttattatt tttctttgtc
     3181 cccttccact tcttttgttt cttgggcagt cagtaaacct gttgacatgg cacgaccagt
     3241 tagggttgcg ctgattaaat cacggacatt gagtcctaga ccttctgttg tcttgtccat
     3301 ggtcgtcatc aggtctccca ccatttttga ggcattccct tcgccgtaca tggtaatctt
     3361 atcaacattt ccaagtggtg ctgcaatatt cttggcgatt tctggaagaa cattaaccac
     3421 catttctgtc accgctgcat cattaaactt agccatggca tccgccttct tgctgagtcc
     3481 ttctgcctcg gcttcgagtt tcaaacggat ggcttctgct tcggcacgtc ctttggcctc
     3541 aatacctgcc gcttcttgct ccgcagcata cttggcagct tctgcacgcg ctttttgagc
     3601 ttccgcttca cgctgcgttt cgtagagttc tgcttctgcc ttgcgttgac gttcaatcaa
     3661 atctgcttct gcagcttgtt ggcgagcgta tttttctgcc tctgcctgtt tgcggatagt
     3721 agctgagagc tcttgttcac ggaccttaac ttcctctgct tttacttctg cttctttttg
     3781 ttgcttgaca atattggctt cagcagttgc acgctcgatt tctttccgtt gagcttgctc
     3841 ctcaatgcca taggctgcgt ttgcctgtgc cagttggaca tcggaccgac gttttagatt
     3901 agcttgctca atagctagtt cattctgttt cttggcgatt tctaagtctg cagcaacacg
     3961 cgcatcatta gccgccttat cctcacgggc acggacttct gcttgttccc gctctgcttt
     4021 ggcgcgagca tttgcggcat ccttctggat ggtcacaata ttgtcaatac ccaagttttt
     4081 aatgacatcg ttgtcatctg tgaaggattg aaccgtaaag gcaatgattt ccagccccat
     4141 tttagccaag tcaggagctg cgttggattg gactttttct gcaaaagcct ggcggttatt
     4201 gaccatgtct cgcagttcca tctgaccaat gatttcacgc agatttcctt ccaagacatc
     4261 ttgaatagag gcagaaatat ctgcagtttt ccagttaagg aagttttgag ctgccgcatt
     4321 gagcaattca tcggataccc caacctttac ttttacgacc gcgtcagctt ttacgttgat
     4381 aaaatcaaga gtcggcacaa aatctgtggt ctgcacatct gttgaaaact gctcaataga
     4441 gatataggag cgtttttcga taaagggaat cataaaacca gaacgaccaa ttaaggtccg
     4501 aggtttgccc aagccggtaa tgacaatcgc ttcgttaggc ttagcagaca cataaccaaa
     4561 tacaaacaat aaaacaaata gtacaacaac aataattggt atcataattg ccaatatatc
     4621 aaatccaaag tccatattta tctcctttat tccttatcac tcaaatccac acttggcacg
     4681 gttgtcgccg catcatttgt tgcttggaag agctctactt tttcatatcc gaatagacct
     4741 gcatagatgg aggtcgggaa ccgcttgatt tttttattgt aggtagttgc taccgcatta
     4801 tagtctttac gggctaccag tatccgattt tccgtacctt caagctctgt tatcaggtca
     4861 gatacctgtt ggttggctgt caattgagga taattctcag ccactaccaa caatctagac
     4921 actgccgaat ccagctgact ttgtgcctga ttgtagtcgc tggttcctac ttgactggag
     4981 ccgattttag cacgcgcttc tgcaatagca gtaaatattt cttcctcgtg ttccatggcg
     5041 cctttgacag ctgcgactac attgggtatc aagtcatagc gacgttgcaa ctgtgtgtct
     5101 acattggctt gcgcattttc aacctcagca taactgtcaa ctaagccatt gtattgccca
     5161 actgctccca ttcctaaaaa cagcagagct aggactggaa tgagaataac caaccatctc
     5221 tttttcataa gatttccttt ctaactacga ttaaacattc gtaaaaaagc aaacaactat
     5281 cagaagcctt atacgatgcc ttaccatcca gaagaggctc cgccaccgcc gcctcctgac
     5341 caactacctc cgccaaaact agacgatgag gaattagacg agtgatgatt gtgatagtga
     5401 tgatgatcat caaccaacat ccagagtaga ttgcctggac ctccaccacc acgactagat
     5461 ttgtcaatga taccaaatag gatagcgatc agaataacta tgagaaacag ccagaagccg
     5521 tcatccttct cacttgtacc ttcttctata gcagctaact gatttttacc aatgcttgta
     5581 ccataaaatc tatccccaat ggagttgacg atataggaaa ttcctctact gtagtcttcc
     5641 tgtcgaaaga attcccttgc attctctaaa atatccttgg cttccacatc tgtcaacacc
     5701 gttgcagcat tgtctgaggt ttctatccga aatgctctgt cagctatggc aaccactaaa
     5761 agaactccgt tgtccgttct tgcaaaaccg acctgccagt gacgaaaggt ttcattagcc
     5821 aaactttcaa tatcactgga cagactttct gttacataaa caccaacctg taaagcttgc
     5881 tcggtgcttg cccaacttcg attgagttga tcaatttctg caatggtctc actcgagagt
     5941 aactgcgtct catccactac cgttgtacct gtggggcggt ctgggatctg atttgctcta
     6001 gctagtgtgg gtgcaaatag caagcaaacc gttagaatag cgaaacagcc gatgataatt
     6061 tttttccatt ttctcatcag aacacctcct tcgatgaaca aagataagaa aaatttatta
     6121 ggtatatata tacaattata tcatattatc attttcccaa caatatattt atgttgtttt
     6181 tcagtatcgg tagagtctgt tcaacaaacc aaggatgttt agcttgccag atattgtttc
     6241 taggtgatgg atggggcaaa ggaaaatagg tgggtaggta atcatctgca tgtttcactc
     6301 tctccgtcag gttcctttgg gatttttcca aataataagt ttgagcataa ttgcctacca
     6361 atatggtcag ctcaatctgg gggagttgct tcataatgag tgggtgccat ttgggcgcaa
     6421 aatccttgcg aggcggcaaa tccccagact tcccttttcc tggataatag aaatccatag
     6481 gaagaatggc aaaatgaccc gattcataaa aagtctgtcg atccacgccc aaccattgac
     6541 gaaggttgct accactggcg tcgtcaaata aacgcccttt ttcctgggtt ttcaagccag
     6601 gtgcctgtcc aataatgaga atttttgcgg tcgaaggggc ttggaaaagg ggagctattc
     6661 ccttgttcgt aaaatctcgg ttagcaacat cctcaatgat ggcttgacga atatcagcaa
     6721 gttccatgat gtcctacttt cttgactatg gtcacatctt cttctaaggc tcggaaaacg
     6781 cattttttgt agaaagaata ggctaaaagg ttgcgttcgg tttgcagaag aatatgaaca
     6841 atctttctat cagctaactg cttctcaata tcagctaata aactagcacc atgtccttgc
     6901 ccttggtaat cacgggaaat acagaactct tcaattcgat actctgttcc ctcataccaa
     6961 tagcgaatgt aaccaagtga cagccctatc aatttttctt ggtcaaacaa gccaaaacag
     7021 agtgctcttg agtgtcccag taaatcgcct atgtagcaat ctaattgttc ctcatctgac
     7081 caatcatcat tccaaggttc ttggctgaaa acagataaaa ataattcttt aaccatttcc
     7141 atgtctgaaa aataaagttc tttcagttcc atatttcctc ctaaaaaaga cgggcgtacc
     7201 cgtcttcatg tattacttaa tgagttcgta gatagcttct gcataaatgg cagcggcgcg
     7261 gtagagttgc tcaacttcga taaattcgtt ggcttggtgc atggtgttga catcgcctgg
     7321 gaacatagct ccgtaggcaa ccccgcgttt gagcaagcgt ccgaatgtac cacctccgat
     7381 aacttgttcg tgacctttca agcctgtgtg tttttcataa acagacaaga gggttgcgac
     7441 cattgggtca tcgattgggc aataatgtgg agtatggcca tgctcagaca ggctaacagc
     7501 ttccacgccc agtttttcca aaccagcctt gatggtttca gggttggtat tttttggata
     7561 acggaagttg agggcaatgg tattgtctga tgaagtttcg tcaaatttga aaacaccagc
     7621 gttcatagaa agagctccca tttgctcatc gtagatggct acgccgagtt ttttagcgtc
     7681 atggtcttcc agaaggactt gacctgccaa atccaaatag gctttggctg cttcgtcaaa
     7741 ggcgaattgg ctgaggaatt ttgccaagta ggttgctccg ttgacccctt cttctggggt
     7801 tgaaccgtgg gctgattttc cgatgacggt gacttgaact tgaccgtttt caagggtttc
     7861 cgcatcagct tttatgccat aggctgctgt gaaatctact aacttgctgt ccagatctgc
     7921 taggtcgcca gagataatag ctgtcgcaga ttcaggcacc atgttctcac gcaggccgcc
     7981 tgtgaaggaa tgcagtttag cagctccgct attttccccc gcaaaatgaa gataagctgt
     8041 gatattgccc ttttctccgt tgataatcgg gaactcagcg tctggagaga atccgaaatc
     8101 tggcagggga aggccgacgt gctcgaagta gtaatccatg tccgcccagc ctgactcttc
     8161 gtcggtaccg acgatgaagc ggactttttt agaggtcgaa aggcccaact ccttgatgat
     8221 tttcaagccg tagtagcaag ccatggtcgg tcccttgtcg tcagaagatc cgcgggcaaa
     8281 gagcttgccg tcaatgattt gcggctcgta tggatcagtg ttccaaccgc ttcctgctgg
     8341 caccacgtcc aagtgaccga agataccgag gacttcgtca ccctcgccaa attcaaagtg
     8401 acctgcgtag ttgtcaacgt tcttggttgg ataaccatca cgctgagcaa tttctagaaa
     8461 cttatccaag gcacgcactg gtccaggtcc aaatgggtgt tgggcatctg cctggctatc
     8521 gtcacgctca gaattgatgc ggaggaggtc aaagaggtcc gctagaaact catctttgcg
     8581 tttgtcaaac tctgctctaa aatttactgt catatgttct ccttttcagt atcaaagtaa
     8641 gtctatttta tcacaaaatg aaagagattt cacaagtaaa gcgaagaaaa aaagttggtc
     8701 tcccaacttc tttctatttt ttccaagcag atcgttctgc tacaactgta aacaaaacat
     8761 cagttgatga gttgagggct gtttcacaag agtcctgaat cactccgacc acaaatccga
     8821 ctccaactac ttgcatggct aactcatttg gaataccaaa aagactacat gctactggga
     8881 tgaggagaag cgaaccacct gctaccccag atgctcctgc tgctgatagt gatgcaacaa
     8941 cggataaaag aagagctgag ctgaaatcaa cactaatgcc aagtgtatga acagctgcca
     9001 ttgttaaaat attaatcgta atagccgcgc cagccatatt aattgtggca ccgagcggaa
     9061 tggatactga gtatgtatct ggatccactc ctaaacgttt gcagagctgc atattgacag
     9121 ggatattagc tgctgaactt cttgtaaaaa atgccgtaac cccactaact cgaagacatt
     9181 caaataccag cgggtacgga tttttcttca ttacaagaaa agcaatcaag ggattgacaa
     9241 caagcgcgac aaaaatcatg cttccaacca agagtaagag cagtaaacca tagtctttta
     9301 aagctgtcag accattattt gcaatggtat cgaaaaccaa gcccatgata ccaaatggtg
     9361 ccagaccaat aatccatcct acaactttag aaatcacttc cgccgtagat tgcaataaat
     9421 cttttgttgt cttgcttgca tgacgaaagg ccaagccaaa cactgccgcc catgtcaaaa
     9481 caccaatata attagccgtt gcaagagcat tgattggatt gtcaacgacc ttcaacaaga
     9541 ggtcttggaa tacttcagca atcccttgtg gaggagtaat gtccgtagtc gttgtagtag
     9601 aaagaaccag tttaataggg aataaatagc ttgctcctac agcaatgaag gccgccgcaa
     9661 aagtgccaaa tagatacaag caaataactg tcctcatatt cgatttttga ccagcaggag
     9721 cttgtgatag agcatgtgca actagtgtca gaaccaaaag aggggctata gctttcaatg
     9781 ctcctacaaa tagactacca aagagagcaa tgaccgttat tttgggagca attaagccta
     9841 gtaacactcc caaaacaaca ccaattccga tttttcggat taaattcatt tttttccata
     9901 cagatattat tttattcact catttacctc caaacaaaca tttttcaatc atagcagaaa
     9961 aatccagtca ggtcaatagc cttggcttct aaaatctatt ttctgcatga tgcaatctat
    10021 gtgtggcgcc cattttttta cgaataaata tgcatctgta atcaaaataa aatactttat
    10081 aagctttatc tacttactgc ccagacctca acgatttacg caatcatttt gttacctaaa
    10141 cagctaactc cactacttac ttttatttca aatgatagct aggtaacact gacctgtaat
    10201 ttttctttat gtgcgaaaaa tgtgttagga ttgcaatgaa aagccctgcc ttatcagtaa
    10261 agcaggactt tgatggctca agaatatcgc tagtaaatat caatattttt gataccattc
    10321 ttatcaaata attgtgtttt catctccgta gtcaacggag taataacgat ttttgaatta
    10381 gaatcaatat tggatacgac accgataatg cgaccgtcta caacgacagg tgacccggat
    10441 tgccccttaa cacctgtgat attggtttga agcaaaccgt cataacggac ttccgtaatg
    10501 gttccatatt cgtattccca acgtccgtag agattaatgc tgttgctgac cattagaaat
    10561 tgtcggccaa ctaggtcata ggtgttacgg taaattccta gccgagcatt tgccgtattg
    10621 gctgtctgtg tttttctgct aggggtggtg attttcacaa gggctacgtc tcgactagca
    10681 tcccatgttc caccatatca tggcatctga atgaagggat tgaagggatt ggttctctta
    10741 atttctgaca gttcatagta tggtgaagca tcgccccaaa cagcatttcc agaccaagtt
    10801 tggctggtca cacgtccagt cccatcatct gccactacgt gaactgcggt taataaagta
    10861 ttcggagcta ttagaatagc tgaacttttt tggtttgacc ggaaccaaca tttacttcca
    10921 aataatgaga taaattatat ggataactat tgcgtagagc tggatctgaa acgtgagtcg
    10981 tctgtgcttc aacctctact attgtaggag gagctaccga tagaccgaca ctaagaaggg
    11041 ctacgccaag cagtaatttc gttttcattt gaaaacctct tgttttttct ttcattatat
    11101 caatcctaat tataaagtgc aagcgtttcc aagtgttttt tgttcaacaa tttaggctct
    11161 tctcatccat tgacaatagc tcaaaaatag gaccagtgct tatctaacta gccctgttaa
    11221 aatactttct gtcagaagta tttgcctacc actttatcga taaattcgct aggtaatctg
    11281 aggcaaattg agtcaagcga ttgcgactgt ctttggattc ataaaaatca atcatggcaa
    11341 aaccagctcg taattgccca gcaatctgtt cttctaaggt gtggctaaat tcatagccat
    11401 attctggatc aatcgtaatt tgtcctgctt cttctaattg tcgtgcgttg aaaggcaggc
    11461 tgtactttgg aaccaaggtt ttgtctggat gctcccaaac atcatcagca tcaaagacat
    11521 aaatccaagg gttcatataa ccgaccatga gcagaccacc ttttttcaaa acccgataag
    11581 actcctgcca catattggcc aaatcttcga tataaatatt tgaaaccgga caaaagatga
    11641 tgtcaaaact ctcgtcttca aaaggaaagg cttgtgtcat atctgcctgg accgtttgca
    11701 aatccagatt ttctcgctca gcaactagcc tatccttgtc caactgttcc ttggagaagt
    11761 ccaaaatagt tgtctcatag ctatgagccg cagaaattgg tccctgttga ccaccaccac
    11821 aggccaaacc cagcaatttc ttacctttgg ctttttcaaa ccagtcaagc ggtactgtct
    11881 ttccaaccgt caaagaaacg gataagggct tatctttggc aacaagaaat tcctcatgac
    11941 tgagcggaac tgtataggca tttccctgtc tagctgaaac ccgattccaa cgttcttgat
    12001 tgtagtttac ataatctgtc atttttcttt cctcgcttga ggcctagcca atatgacctc
    12061 gttctgttct tttcattttt cacctccttt actatgctaa ttctattatg gcataaagaa
    12121 agagaaaaag ctacctatcg atagctttta gtctacgtca agtcgttaaa atcccagaca
    12181 tcgtccaccc agccttcata gaaatcaggc tcgtggcaga ccatgagaat tgagccctta
    12241 taggcttgaa gggcacgttt gagttcatcc ttggcatcca catccaagtg gttagtcggc
    12301 tcgtcgagaa ccaggacatt gttttcacgg ttcataagca aacagaagcg aactttggcc
    12361 tgctcaccac ctgaaagaac ttgaatttgg ctttcgatat gcttggaagt cagaccacaa
    12421 cgagccaagg ctgcccgcac ttctgcttga ttgagggctg gaaaggcatc ccaaacgact
    12481 tccagtgggg tctgacgatt gccgccagct acttcttgtt caaaataacc gagttccaga
    12541 tactccccac gctccacaga gccaccgagc ggtggaataa tccccagcaa acttttaaga
    12601 agagtagatt taccgatacc gttggcaccg acaatggcaa tcttctggtt gcgttcaaag
    12661 gtcagattga gcggcttacg ggtcaggaca cggtcgtaac caatctccaa gtcagtcgtc
    12721 tggaagataa agcggcttgg cgtccgagcc attttgaaat caaatgatgg ctttggtttc
    12781 tctgcttgaa gttcaataat ctccatcttg tccaatttct tctgacggga catggccatg
    12841 tttcgtgtcg caactcgggc cttattacgg ttaacgaagt cctgcaagtc tgcgatttcc
    12901 ttctgctggc gctcataggc cgcctccaac tgagcccgct tcatagcatg tacttcttgg
    12961 aattggtagt aatcccctgt gtaacgggtt aagagttgat tttccacatg gtagacaatg
    13021 tttatcacat cattcaggaa aggaatgtca tgcgaaatca agacaaaggc attttcatag
    13081 ttctgcaagt agcgtttgag ccagtcaata tgctctgcat ccaagtagtt ggtcggctca
    13141 tccagaagca agatgtcagg cttttccaag agcaattttg caagaagaac tttagtccgt
    13201 tgtccccctg ataactccgt aacatccttg tccatgccat aatccatgac accaagcgca
    13261 cgcgccactt cgtcaatctt ggcatcaagc gtatagaaat cacggctttc cagacggtct
    13321 tgcagctcac caacctcttc catgagggca tccatatcgg caccctcttc tgccatagac
    13381 atgtaaatgt cattgatacg agcttctgtc ttgaagagtt catcgaatgc tgtccgcaag
    13441 acatcacgga ctgattgacc cttttctagt ttagcatgct ggtctaaata acctgccgtt
    13501 acataacgtg accattcaac cttaccttca tctggctgca attgacctgt cacgatggac
    13561 atgaaggtcg atttcccttc accatttgca ccgacaagtc cgatatgttc ccctttcaag
    13621 agacggaagg agacattttc aaaaattgcg cggtcaccaa acccatgact taaattcttt
    13681 acttctaaaa tactcataat ttcctcacaa catcaaagaa ctggagtaac caaactccag
    13741 tttttacttt tattctcgca gtattgagcg gaacttcttc gcctatcagc tgtgaaattc
    13801 ctactcaacc ttgcgggggt tagacaacaa aatcaaactc tacgagttac tgatttctgt
    13861 ctaactccca atttccgcac gaaccacatc ggcaatggtg tccacgtagt aatcgacttc
    13921 agcatccgtt ggcgcttctg ccatgacacg caagaggggc tcagtaccac ttgggcgaac
    13981 caagatacga ccgttgccag ccatttctgc ttccattttt tcaatgatag ctgcaatagc
    14041 aggcacttcc attgccttgt ccttcatgct attttccaca cgaatattga ccaatttttg
    14101 tgggtaaatg gtcacttctg ctgccaattc tgacaacttc ttaccagttt ctttcatgat
    14161 tttggtcaat tgcacagcgg tcaactggcc gtcgcctgtg gtgttataat ccatcagaat
    14221 cacatgtcct gactgctcac caccgacatt gtagccttcc ttgcgcattt cttcaaccac
    14281 ataacggtca ccaactgcgg tcacagcttt ttcaatccct tcacggtcca aagccttatg
    14341 gaaaccaagg ttagacataa ctgtggtcac aattgtattt ttggccaata gacctcgatc
    14401 agcaaggtat ttaccaacga tgtacatgat gcggtcgcca tctaccaaaa caccattttc
    14461 atcgacggca atcaagcggt cactgtcacc atcaaaggca agtccaattt gactacctgt
    14521 ttctttgacc agttcttgca atttttcagg atgagttgaa ccaacaccct cattgatatt
    14581 caaaccgtct ggcttttcag ccattactgt caaatctgct cccaaatcta caaaaatttg
    14641 acgtgcagat gttgcagcag caccattagc tgtatcaagt gcaactttca taccgtccaa
    14701 atctgtacca gttgatacca agaattgctg gtacttacgt agaccttctg gatattctac
    14761 cacatctcct aaaccttgag cagatgggcg tggcaatgtg tcttcctcag cgtcaagaag
    14821 agcctcaatt tccgcttcca atgcatcatc caatttgaaa ccatcaccag caaagaattt
    14881 gataccgtta tcttgcgctg ggttatgact tgcagaaatc atgacacctg cacttgcttt
    14941 ttcagttttg actaggtggg caacacccgg tgtcgccaaa actcccaatt tatacacatg
    15001 aatccctact gatagaagtc ctgcaatcaa ggcagcctct aacatttgac ctgagatacg
    15061 tgtgtcacgc gccacaaaga cacgaggaac atctgtctca tgctggctaa ggacataacc
    15121 tccaaaacga cccaatttga atgctaattc tggcgttaat tctacgtttg cttctccacg
    15181 gactccgtcc gtaccaaaat atttacccat tttcataacc tcttattttg tttttgtaag
    15241 tataatttgc atatttgctt ccgtctgaga cagtacaact ggcaagacat tgccgtcgct
    15301 atctacagcc tgtaatttag ctgtaccact ataattctca gacagattgc tcacatccat
    15361 cgcaacagct tcgacccgat caatcttagc cattgtttct tcatccgttg tcactttaac
    15421 ggtatctacg ttgactgaaa ccttagacag actgtaacct tctgccaatt gattactata
    15481 gactcgacct gctactggga atgccttgct aactttttta ccaatcttga cggtaatcgc
    15541 atcaggtgct agtgtcgcac tcactccagc cggcaaattg gtcaattgta gcttgacagt
    15601 ctgtgtccca tcactcaact ctctcaaatc cgcagtcact tgaaaagtcc gagttgactc
    15661 atctgattct ctctgtagga gaacacgatt agagcccctt aattcaactg ccaccgtcga
    15721 agaaaatccg gaaataaaat acttgtttgt atcatattca atctcaatcg gtacattgct
    15781 cagtgtgtga acataggttt ctgactccgt gttctgtgca gctgattctg aatttttata
    15841 gttggtggtt gttgcataga aaaagagcaa caatgctaga aaaatagata aggctaagtg
    15901 acctacagct ttaaacttat cattcatgtt tgccacctcc taatcgcttc cagatggact
    15961 tcttctctac attttcagaa ataaaagtcg ctcgcaactc tgcttcaaac tcatccaaag
    16021 tcaaatcatg tttaaatatc ccgtttcgtg caatagagat actgccagtt tcttcagaaa
    16081 caataaatac aaacgcatca gatacctccg ataagccaat ggctgcacga tgtcgtgttc
    16141 caaattcctt tgaaattcct gcgctctctg acaggggcaa ataagcacaa gcaacagcta
    16201 ccttgtcttc cttgacaatt acagccccat catgtagcgg tgtattcggg atgaaaatat
    16261 ttattaacaa ttcctgagat atatccgcat tgagtggaat ccccgttgct ctatattctt
    16321 gcaatgtttg ggcttgttct actgccacaa gtgcaccaat tttacgcgga gacatataag
    16381 caaccgattt gagaaaagca acaattaact tttcttctgc actcactgta tttgtcccaa
    16441 aaatctgagt tgttctaccg agtttttcaa gcatagcgcg caactctggt gcaaaaataa
    16501 ctactgctgc aataacccca tacgtgatta cttgattaat cagccaagca atcgtctgca
    16561 gaccgaataa actagctata atctgaacaa taatgaagag aaaaacccct cgaatcaatg
    16621 tcataatttt agtacctgca atagacttac taaaattata aatcaaataa acaactatac
    16681 taatatcaat taggtgcaac agtgcggtcc aaggactggc tatcaaactc gaccaatacc
    16741 ctgtatccag taactggttt aggtttaaca tatcattctc atactttcta actcatacat
    16801 agtaatgtac tcattatacc atattttttc cccttttctt tagaaaatag tgaccttcct
    16861 gttaaaaata ttacagattt actgcaggaa tatatcatgt tccaacatac tccattctag
    16921 aaaatcccca acctttatga taaaatagtc ccatgaaaat aaatacagct ttgggtattc
    16981 tagcaggaaa aagttcccag ttcattttga aaaaactagg acgtggtact accctacctg
    17041 gaaaaattgc cctcaaattc gataaacata ttttagatag tttggctaag gattatgaag
    17101 tcgttgttgt gacaggtact aacggaaaga ctctgaccac cgccctgaca gttggtatcc
    17161 tccaagaagc ctttggcgaa atcacgacca ataccagcgg tgccaatatg atcacaggaa
    17221 ttacggcaac ctttttgtct gccaagaaaa ataaaaacgg caagaagatt gccgtcttgg
    17281 agattgacga agcaagtctt gcccgtgtaa ccgactttat aaagcctagt ctgattgtct
    17341 ttaccaatat cttccgtgac cagatggacc gctacggtga gatttatacc acctaccaga
    17401 tgattttgga cggggctgca aaagctccgc aggcaactat tttggccaat ggtgatagtc
    17461 cacttttcaa ctcaacgaac gttatcaatc cagtaaaata ctacggtttt gcgacggaag
    17521 agcatgagcc acgtctggcc cattacaata ccgaaggcgt tctctgtcct cattgccacc
    17581 agattatcca gtacaagctc aatacctacg ccaacttggg tagctacatc tgtaccaact
    17641 gtggctttag ccgacctgaa ctggactaca agttgaccaa actaaaagaa atcaccaata
    17701 cttcttctac ctttgtcatt gacggtcagg attataagat taacatcgga ggcctctaca
    17761 acatctacaa tgccctagca gctgtcagcg tagcagaatt tttcggcgta tctcctgaaa
    17821 aaatcaaggc aggatttgac aaatcaaagg cagtcttcgg tcgccaagaa acatttaagt
    17881 tgggtgataa agattgtaca ttggtcttga ttaaaaaccc tgtcggtgca acccaggcta
    17941 ttgaaatgat gaaactggct ccatacgatt ttagcctgtc cgtccttctc aatgccaact
    18001 acgctgacgg aattgatacc agctggattt gggatgctga ctttgaacaa atcacccaaa
    18061 tggacattcc acaagtcttt gcaggcggtg ttcgttcgtc tgaaattgcc cgtcgcctcc
    18121 gtgtgactgg ctatcctgag aaccagatta ctgaaacacc aaaactagaa gacatcatga
    18181 ccttgattga gcaatcgagt agtcagcatg cttatatttt agctacttat acagctatgc
    18241 tcgaattccg tgacctgctg gctcaacgcc aagccgttgg aaaggagatg aaataatggt
    18301 ctatacgtca ttaaaaagtc ctgaaaaaga ctacacttac gatctccaca tcgcccacct
    18361 ctacggtgat ttgatgaaca cctacggtga caatggcaat atcctcatgc ttaagtatgt
    18421 ggctgaaaag ctgggggctc gtgtccaggt ggacatcgtt tccctgacag atgaatttga
    18481 caaaaatttc tacgacatcg cctttttcgg cggtggacag gactatgaac aatccattct
    18541 tgctaaggat ttaccgacaa aaaaagacag cctagcagac tttatcgaaa acgatggcgt
    18601 catgctagct atctgcggtg gcttccagtt gctcggtcaa tattatattg aagctggcgg
    18661 tcgcaagatt gacggtctag gaatcatggg ccactacacc ctcaaccaga ccaataaccg
    18721 ctacatcggt gacatcaaaa ttcacaatga tgagttcaac gaaacctact acggttttga
    18781 aaaccaccaa gggcgtactt tcctagctga caaccaaaaa ccgctgggca aggttgtcta
    18841 cggcaatggc aataacaagg aagacggcgg cgaaggtctg cactacaaaa acaccttcgg
    18901 tagctacttc cacggaccaa tcttatcccg caatgccaac ctggcctacc gcctggtcac
    18961 tactgccctc cgcaaaaaat acggacaaga catccaactt gccagctacg ccgacatcct
    19021 cagcaaagaa gtcgctgaag aatacggcga tgtaaaaagc aaggcagaat ttgatactca
    19081 atgaaaatca gaatcagact aggcgacgca gatgcagata gaactgaagt tcatcaaatc
    19141 aagtcaacaa cgtctgactt tgattttcga agagtatgag aaataaagca aaaccgcttc
    19201 tgatatccag aggcggtttt attttatata cttccaatca aaagtaagcc ctccaccgtt
    19261 atctccgtca attgactcaa atccagcttg gactggtcca cttggaaaaa gaggggtgtc
    19321 atgtctgcca aaatacgagc ctgctctata ccaatcggca gggtccggct gaccacctct
    19381 tgctccacct gtcccatgta agacttgaaa tggtccacga tatcttggtt gtcataggac
    19441 tccttgcgga gttggtcttt ggctaaatgg cggagctcct tgaggtgatt ggggcctggg
    19501 actagtttga gaatagcccc accagctttc agcactctgg caaattcctg ataattggct
    19561 ggggagaaga tgtccaagat cccgtcgatg gtcttgtctt gaatgggcaa cttggtcaag
    19621 tcaccgacaa accatttgac cgacttggtc ctgtctgttc tggctgctag gagaatagaa
    19681 tccttagaaa tatcaaaagc aagaatgtcc aagtccattt tctcggctaa tttacgggaa
    19741 taaaagccct ctccacagcc gatgtccaag acagaccgca atcccagctc tgctattttt
    19801 tcctccaaag cctcgtagag atgatcgtaa tagcccgcct ctaaaaaggc ctgacggttt
    19861 tcaaagctag acttgtggta gttggcggac tgcttgacct ggggtgccag gttgacgtag
    19921 ccctgcttgg caatgtcgaa ggtgtggcgg ttggggcagc gaaggctgtt gaggtcaaga
    19981 ccaagagcct gcccacaatg tggacaggcg aaaaattggt cgctattggc aaaacgttgg
    20041 tgtttggtca tcttatttgt gttcttttct aaagcggtgc agggctagtc ctgataggag
    20101 cgtggcaagg gctcctgtaa agaccagcaa gtagccgact ggaatgagat aaaaattttc
    20161 atgcagaatg ccctcggcat caatatactc gaccgagttt gccttgatga caaagcagac
    20221 gaagccgaga agcatgagaa aactaccaat aatggtaatg gtcaggtgca tctgggtacg
    20281 gcggccttca cgaccgtctt ttacaagttt ttctgtcatg ttgttcatat cagttcctcc
    20341 taagataagt tgatctaagg agatcgaaaa gacagaggac atgagaatca agagctccaa
    20401 atcaggtaga ttcttgtcat tttcccagtt ggaaacagcc tgcctggtca cattgagttt
    20461 gagggcaaac tgttcctgag tcaaaccttt cttttttcgt aagtctttga tttgctgtcc
    20521 aaagttcatt tctttctcct ttctgggagc gggacagaac tcgaaaaatg aaaaaaagtt
    20581 cgtcaacaat ttttcgtttt aagttgttga gctgaaacag tctatcccca gactgtttca
    20641 ctcccacccc cgcacagctt aaactgtctg ggggacagtt taaggttggg aataaagcga
    20701 acaaagttcg caacattcgt taggccagat ttgaagtgtg caacacgaac aaatctgcca
    20761 atcaaccact gcgctgagat gttgacacca ccttcgagaa gtgatgctaa tctctatact
    20821 gatcttagct tgtcggtcga tgttttccaa gaaagactgg cttgctctgg acttttttag
    20881 cgaaaagtgg tcgttctaac tccgcaagac tggcttgcaa gcttgttcta tcaagggttt
    20941 gagcctcttg tcaacttgct gtcaacctag cccatctgct cagataattc ttcccattct
    21001 tccatgagac tttcttgttg gctggtcagt tggtcgattt ctttctggta atcggtcaac
    21061 tggccgatgt cgttggtttc tagcatggct tggttgagct cgttcaggcg gttttcgatg
    21121 ctatcgattt ctgcctcgat ttgctcgatg cggcgggcta gtttgcgttg ctctttttgg
    21181 ttttcctttt gggcttggta gtccatggct ccagctgatt ggctggtact ttctagctgg
    21241 tcaggctggg cttctgcttc cagctctgct tttttctcca aataataatc atagtcgccc
    21301 aaatagagcg tggagccagt ttccgagatt tccagcacct tggtggcgac gcggttgatg
    21361 aaatagcggt cgtggctgac aaaaagcagg gtgccgtcaa agtcgatgag ggcattttcc
    21421 aagacctcct tgctgtcgat atccaagtgg ttggtcggct catcaaggat gaggaagttg
    21481 ttgttttcca tggacagctt ggcgaggagc agtcgggctt tttccccacc cgatagcatg
    21541 gaaacggact ttttgacatc atctcctgag aaaaggaaag ctccaaggcg attgcggatt
    21601 tccacttcag gtgtagtcgg aaaggcggac cagagctcct ctaagaccgt attggaaggt
    21661 gtcagggccg actgggtctg gtcatagtag cccacttcca cattggcacc gagccaggct
    21721 tcccctttga taaatggcag agctccgacg atggatttga gcagggttgt ttttccgatt
    21781 ccattcggac cgacaatggc aatggcatcg agtttccgtt ggtcaataga aatgggctgg
    21841 gaaagaatgt ttccatcgta acccaccgca gcattttcca ctgtcaagac gatattgcca
    21901 gaagtcttgt ccgactggaa ggtcatattg gcagacttct gaccagttgt cggcttgtcc
    21961 aatcgatcca tcttttccaa ctgcttgcgt ctagcctgag cgcgcttggt ggtcgaagca
    22021 cggacaatat ttttctggac aaagtcttct agtttggcaa tttccttctg ctgcttttca
    22081 tagttttgca attctgtttg taacttctgc tctttgagct caacaaactg agaataattg
    22141 cccacatagc gatccaagga atgcttggtc aaatccagtg tcagtgtcgc caccttgtcc
    22201 aagaaatagc ggtcatggct gacaataatc aaagctccct tgtaatgcac taggtagttt
    22261 tccagccaag caatcgtgtc gatgtctagg tggttggtcg gctcgtccag gaccaataac
    22321 tctgggcttt caagaagcat ttttgccaga gcaagtcgag tattctgacc acctgagagt
    22381 tcggagatct tcatgtccca catggtctgg tcaaacttga aaccattcaa aatagcacgg
    22441 atgtctgcct catagctaaa accacctgcc agacgaaatt cctccgacag actatcatag
    22501 gtcttcatga gctggtcgag ttcattacca gaaagactgc ccatttgctc ttccatagat
    22561 cgcaggcgtt tctccgtcat ccgcagatcg tcaaagacat ggagcatttc atcgtaaatg
    22621 gtattttccg actcaaaaca gctgtcctgt gccaggtaag aaagggacaa atctcgcttg
    22681 gtagaaatct cgccgctagt cgctgcttct tctccgacaa ggattttaag caaggtggac
    22741 ttacctgccc cattttttcc gacaagagca atccgatccc gctcatccac ttgaatgttg
    22801 atattgttaa ataaaacttc gcccgcaaat gagcgttcaa tcttgtttcc acttaaaata
    22861 atcataaaaa tattgtacca taatttaggg taacagtgcg gaatcctttt tctgatttca
    22921 gcaaaaaaca gcgactttac cgtcactgtc cttctcaaaa aatatttaga ccaaaccgct
    22981 aagcaattcc ttattctgcc agagtagata aagaccaccg ccgataataa tcagcataat
    23041 gacaaactta atcaagccct taacaaagcg gatgaccaac atcaatatca tagatacaat
    23101 cagccatccc caagcagaag aattgagtaa ggtttgcata ctctctagac ttgcacctgt
    23161 ccaggcctta attggttcag ggattttatc aaaccagttg ctatctatac cgatttgttc
    23221 cataatcgaa tgactggtag actgcatcca tgcaaaaatt ccagcattat agagaaagag
    23281 cagagcttgc tcaggataac gttttattgt gtttgtaatt gttcgaagca tattttccct
    23341 tctattctga atacaaggca aggaccgcat caatatctgc ctgctggata ccatgattag
    23401 aacctgccga ttccataaca gaggtctgac tatcttcatg atctaggcca atagcatggc
    23461 ccaattcatg ctcagctgta tggataattc tatccatatc ataaccatat tggtcgttta
    23521 ataaataaaa actattcaga cacaccgtta ccgagctata ataattcgtc aataaattag
    23581 tcgttgaatt ggcctcacct gctgcctggg tatttccatc attcatctca gtagcaataa
    23641 tatcagcctg atttggatca cttgtcatca caaaagtaaa tgcccctgtc gcattccaat
    23701 ttgcaatggc tgtttcatag gcagctacaa atgttggatt ctgagtttca atgtaaacag
    23761 tcgcagtatt gctttcccat cgaccatgat cggctgtatt gaccgtatca gtcgtcactt
    23821 cagactgtcc tttaaccatc agttgcactt cttgaggtag agtttgtaac atctgaggcg
    23881 ctgcttcctg ttgaaaatag aataatagac ctagaccaca agccaataac accattgata
    23941 accaaatcag accccaaaat gtccgccaaa tccaccgtag aatatttcca ataagtttca
    24001 tagactatac ctctttctag aaataggttt tagtatagcc ataatttctg aaacttttct
    24061 taaaaactag gacaatcttt cttccaattt gaaatcaatt ggcaaccaag ccaatacttt
    24121 ctcaatctgc tgattccagt agtaccactc atgtttacca ggtccgaaac ttgcctctat
    24181 atcaaatccc agctctttca actcctcaac tgccttttga tgcccttcaa agagaaaatc
    24241 ttcctcacca caccaggcat aaaatttggt ctttttatcg gattgtttag caatttctaa
    24301 caaattattt ggattctgtt tatcagaaat atcaccaaat actccttgcc aatacgaaag
    24361 acttcccaat tctgctgccg ctggattatc aaaatcaaaa tacaatgcgc ctgaaagcga
    24421 agctgcgtgt gaaaagcgat tggtcatcat ggcaatcttg aaagtcccat atccccccat
    24481 agacaaacca gcaatgaaat tcttctcccg cttgtcagac atatttggga aaaaccgctt
    24541 gaggatttga ggcaactcaa tcgctatggc atcataataa ttcataccat aggtggtatt
    24601 ggtgtaccaa gccttatccg tattaaccat aacaacaatc aaattagtat aacgaaccaa
    24661 gcgttcaatt gtagaccgat tgagccagga atcctggttt cctcccatac cgtgcaaaag
    24721 atataggaca ggaatgtcgt tgtcatcggg attttccaca cgatttcgat ctggatataa
    24781 aaccgtaacc tgtctagaca tatctagagc ttctgagtgg tattcaattt tcattattgc
    24841 cataaatctt ctccttatgg taaagagcct gagtttccct cggctcttct tatgtatata
    24901 aatcagctta cttgacttcc ataatcaccg gcaaaatagc tgggcgacgt ttggtttggt
    24961 caaagaggaa ttttgctaaa tcatcgcgaa cagcactctt aagctctgcc cagtcaaagc
    25021 tatcctttgt aaagtaattt tccaccgttg tattcaccaa ttctgatgcc tcacgcaaga
    25081 tgtccttgct ctttttcacg tagacaaaac cacgagtatt gaccttggct ttagaaatga
    25141 tttttttctc acggcggttg acagtgatag ccacgataaa gataccgtct tctgagagga
    25201 tcttacggtc acgaaggacg atatttccaa catcgcccat ggcatttccg tcaatcatga
    25261 catcaccagc cggaaccgct ccgctatgga caaaatcccc ctcttcaaaa gccatgacat
    25321 ccccacgctt aacgatgata atgttttctg gatacatacc gatttcaagc gcagccttag
    25381 cgtgagcatc caattgacga tactcccctt gaactgggaa aagatattta ggcttcatga
    25441 tgttgagcat gagctgcaaa tcacgcgcat tcccatgccc agagacgcga agattctttg
    25501 tgatagattt tacggtacca ccagccttgt aaatcaagtt ctccacacga gcaacaaccg
    25561 cttcttttga aatacttgga gtggtaacaa tataaactag atcaccttct ttgatttcaa
    25621 catagcgatg tctaccgata gacattttac gcaatccatt taacggctcg cccatacgac
    25681 cagtttctaa aataatcaat tcatggtctt catacttgtt catatccttt ggttttacca
    25741 acaagcgttc gctgaccaaa cgaagttttt tcaattgaat cgctgttcgg acaatgtttt
    25801 ccacatcatg tcctgtcaat acgacacgac gaccagttgc ttctgccgcg tcaaaaatct
    25861 gttgaatacg tacaatattg ctggcaactg ctgccacaat aacacgcccg tcacagtcag
    25921 caatcgtatt gagaatttcc tccccagcct catgcatgct cgctacttga acattgctat
    25981 ctgcattagc tgagtctgac aagagggcca acacaccttc gttaccgatt tcagccaatc
    26041 gcccaaaatc cgtacgataa aacttatctg ccgcctggtc aaacttaaag tcacctgtgt
    26101 agacaatatt tccttcatcc gtcttaacga caattcctaa actctctgga atagagtggg
    26161 tcgtctgaaa gaaagatacc actgaatccc cgaaatcaat ttccgtttca gcattgataa
    26221 catggaaatc attaaatttc ttagtagcat tattcccctt gacaagtagc ttagccaatt
    26281 cgatagtcaa gtgcgaacca aatactggca ctttcacttt ctccaagaga taaggaagcg
    26341 ctccgatagc atctgcatgc ccgtgagata aaaagacccc tgctacacga tgcttatttt
    26401 cttccaaata atcgaaattt gggacgacta catccacacc taactgttca ttctcaggat
    26461 actttgcccc tgcatccaaa acaaaaatat gttcattcac ttcggcaatg tacaggtttt
    26521 ttccattttc ccgcacaccc ccaagagcca taattttaat tgtactcatc tttactcctt
    26581 ttggacatcc cacaggtgtc cattttattt ttcttaccaa cggtccttgg gagctccaag
    26641 tcgaattaca gtctgctatt tatcgtcatt tagtttttct tttattactt cgacgtaaga
    26701 ggaaactccg tttccttatt tctaacttca aacactccac tggactgttt gaactcgcct
    26761 tgcctgattg aaacagtctg ggggactgtt tcaagtcaat gcctagaaac aagaaaacat
    26821 tgagtcatgc ctgcagctcg ttgcctagta ctaaaagtaa actaaaagac tatattttag
    26881 ctatcgcttc tattatacat tttttcaaga aaatttacaa aaaactccgc tgaaaatcaa
    26941 cgaagttcta catatacatt agtaaccatg tcccttatgt tcccacttac caccaacatt
    27001 ccgcactaaa atccatttcc aatccgtatg agtactatta ggctctaagg tgggctctgc
    27061 cccctcagct gctaccttaa aagacgaagt taggataata gcttcctctg caccatagtg
    27121 ctccgcccac tcatcaaatt ccttttcatt atcaccactg taaccgatag tcagcaattt
    27181 acaactgtta aaatggtgat caaagtaatc ttgaactaca agaatagccg cctcaatctc
    27241 tttttccgta tacaattctg attgttccat cggttcaatc tctgcctgat aagctgctcc
    27301 tgtccgacat cctaccaaaa aaaggcaaca caacagacta caaatagcta aacattttct
    27361 catctttgtt acccccagtc aacaatcgtt gctgaaaagc caatctcttc gacaaaacgt
    27421 aatacatcct ccgttttgac aaaaattgtt ttcgtattaa cattggggtg gaaggttaga
    27481 atgggttcgg ataggatttc tttatcaaaa aagacttgaa tatccttatc aacattatgt
    27541 aacaagccaa aaacagatac cgcacccgca ggcaagtgca ttttttccat caagctatca
    27601 ctcgaggcca tccgaatgcg gttggctccc accaaatcac gaaattggtc catatccagc
    27661 tgcttctggt catccatgat cagtaaataa aatgcagtct ttttcttatt agtcagaaac
    27721 atggacttgg tccgtactcc ttctacccct tcaatgtaac ggtctgcttc ctcagttgtc
    27781 agagctggtg gatgctctac aatggtgtag tccattccta agtcagctaa gctttcaaaa
    27841 accaatttat ccatgacagc acctcttgat atatttagta tattatactg ctttttaact
    27901 aaaaattcaa aggataataa aagcctggat tactccagac tttagacctg tattcacaag
    27961 tgatctgttt gatataagat tcagttttag ccaaaaccaa acttagttgg aagttgcgaa
    28021 ctatccacac aggttcttaa tcaaacaact tataataatc ttccagtttc atcttggatt
    28081 tttcttcagc cgtttggtcc tgaataatct gaccattttt catgacaatc aagcgattac
    28141 cgtgacgcag agcatcttcc atctggtgag tgaccatgag ggccgtcatt cccttggtct
    28201 caatcaactc gtccgttaat tgcatcaagg attggctggt cttagggtca agggctgcag
    28261 tatgctcatc caagagtaaa agttcaggct gtttcaaact cgccatcaac aaactcaatg
    28321 cctgacgttg accacctgat aaaagtcctg ctggcgtgtc cagatgtttt tctagaccat
    28381 ttcccactct cggcaaaagc tgggcaaatt cttccgtctg ttgggccaat ctgcgtggca
    28441 gtaagccccg tccctcgcca cggtacttag ctatcagtag attttctgcc accgtcatcc
    28501 gtggcgctgt acccatttta ggatcttgga aaacacgtga caaatactta gcacgttttt
    28561 ctgcaggcca attggtcacg tcctcaccaa gaatatggac tgaaccacta gtcaagggta
    28621 gggttccagc aatgacatta aagagggttg acttcccagc cccattgcca cctaaaatgg
    28681 taataaaatc accctggtag atggtcagat tgacattgtc caaaatcaca cgttcttcat
    28741 caaaaccgtt tgtcaccacc ttggtggcat tttttaattc aacaattgct ttcatcgtga
    28801 cagactggct cctttcagaa gtttattttt caactcagga accatgaggc aagttgccag
    28861 aatcatggcc gagaaaatac ggaggtagct ggtattgatc ccgagggaaa tgaccaccaa
    28921 aattaagaac tgatagaaaa tcgctccgac aacaatggcc aagaatcgtt ctaacatagt
    28981 aaggttacca taaattacct caccgataat cagactagcc ataccgacca caatgactcc
    29041 aataccacgc gacacatccg catagccttc ttgttgtgca atcaaggcac ctgcaagagc
    29101 gatgatccca tttgaaagaa caaggcctag caactccatt cgacttgtat tgataccaaa
    29161 actgcgtgcc atatctggat tatcccctgt tgcaataaag gcctgtccaa ggcgagtata
    29221 gaggaagaac atcaaggcac caatcaccac cgctaggcta cctagaccta gcaagagacc
    29281 attgacttgc tcagaaaaag gaaggaaatc ttgtaaacgt ttggtattca gtaagcctag
    29341 atttgcccta cccatgataa atagaatgac agagtgacag gaagacatga ccaagatacc
    29401 agctagaaga gtgggaattt tccccttggt ataaagcaag cctgtgacaa agcccgccaa
    29461 acagccaaca agaactgctg ctagagtagc caagatagga tgaactcctt gcgtcaataa
    29521 ggtaacagca accgctcctc caagcgggaa agacccctct gtcgtcatat caggaaaatt
    29581 cagaatccga aaggtaacga atattcccaa acctagtaca gcccataaaa gagcctgtga
    29641 aactgttgat acaatcatat ttttcctttt ctcttatctc ttattcgata accttgcttg
    29701 ctttactaat cacatcatct gacaaggtaa ttcctaattc tttagcaact ttttggttga
    29761 caacaacggt accctcgtta aagatttgta caggtgtatc cgctggattg gcaccatcaa
    29821 gaattttcgc agccatctta ccagttgcca cacccaagtc atattggcta agggtaacag
    29881 atgcgatacc tccaccttct accatgtctt ctacgctagt gaaaatcgga gttttggttt
    29941 tatttgccac agatacgaca gttgaaaatg ctgaggcaac tgtgttgtct actggtgtaa
    30001 agagaacatc tgctttacta cttgcgacct ctactgtcgc tgcaatttca ttactagaag
    30061 caactgcata ttcaagaaca gtatagccag cctcttctgc tgctgcctta aattccgcta
    30121 cttgaatttt tgaattgtcc tcatttgaag aatagaggac accgatagtt ttagcgtctg
    30181 gtgtaatttc tttaatgaga gaaactgcgt ctgctactgg tgtttggtca gatacccctg
    30241 taatatttcc accaggattt ttcaaatccg tcaccaggtt ggctccgact ggatctgtta
    30301 cagcccccat gataatgggt aattctgtgg ttgcattggc aagaccttgt gcagcaggtg
    30361 ttgcgatacc aatcaataat tcattgccat tgtccaccaa ttttttactc atggtttgaa
    30421 cttgggattg atcaccctca gcattcataa aatcaatttc taaattatcc gttgtggtat
    30481 aaccaccttc ttcaagtcct gccttgattc ccttataaat ctcatctagt gaatcatggg
    30541 ttacaaactg aagaacccct atcttaactt tctccgttga tgtagatgaa ttgttctgct
    30601 ctttctgtgt cataaacaaa gcagcaacta ccataacagt aagggcaaca attgtagcaa
    30661 gtaaattttt atttttcaac atattcattc tcctcgtaaa atacacaata tacaatttct
    30721 acgtcatcaa tatattatcc caccatcgcc atcgtttcat catgattacc tcgttttgtt
    30781 aataattgtc aaagtagatt gcttttagat aaggaacgga ggcgcagaca taactcaagt
    30841 taggcaagcc gaacgtgacg caatataaaa gcactctacg aagacaatgg aaaagccccc
    30901 gcaggaaaaa acaacctgcg agggcgtcaa tgacacggtg ccacctcact tatgggaatt
    30961 gtctagaatc ctcccatatc tcatctcctc taacaaggag ttgcactgta aggtgtgcgg
    31021 accgaactat cattgtttta agttcattta cgtgactgtt ttggctagtt acttcgttaa
    31081 ctctccttgc tataccgcca gtataagctg cgtcgacctg cctcgtactc agccaaaaca
    31141 gtctacgcaa agtatgctat accaaacaat ccttgtgaat ttagggcatt ttaggactag
    31201 gcagtcgggt gaaggcagta ctggtggtac ggcaagcacg actaacgacg tcataaaata
    31261 gacataaatg cacatcagcc catttcataa aactccgcca cccgttctca gcaccacagg
    31321 ctccctgaag acttctgctt tactacttct tctgattaca gatgattata cggtatccat
    31381 cagtctttgt caatactttt gattaaattt tctgaaaact ttttaatacc ttaagagtct
    31441 attttgagct attgctcagg atactgccat tggattgaat aacttcttta taccagtaaa
    31501 atgatttctt tctatatcta gttagactgc cacttccatc atcatttcta tcaacataaa
    31561 ttagtccata tcttttagat aattgtgcgg tagacataga tacacaatca atacagcccc
    31621 aagaagtata acccatgact tctacgccat cctgtatcgc ctccgcaact tgtaaaaggt
    31681 gttcttgcat gtattgaatt cgataatcgt catgaacagt caaaccacca gcctcatcct
    31741 tgactagctg atctttagct cccaaaccat tttcaacaat gaataaagga atctggtatc
    31801 gattataata acgatttagt gtcaatctta aaccaattgg atcaatctgc caaccccaat
    31861 cagaagcttc taaataagga ttgaccaaac cacccaagat atttcctttt ccagatgaat
    31921 attttgatgg atctgctgcc tgagtaatac tcatataata actgaaggag agaaaatcaa
    31981 ccgtattatt ttttaataac tcttcatcac cttccacgaa agtaatcttt atgccattt
//
LOCUS       DBNFCO010000015        30616 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.015, whole genome shotgun sequence.
ACCESSION   DBNFCO010000015 DBNFCO010000000
VERSION     DBNFCO010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 30616)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30616)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30616
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.015"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            160..285
                     /gene="dltX"
                     /locus_tag="AC1PIV_000598"
     CDS             160..285
                     /gene="dltX"
                     /locus_tag="AC1PIV_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HIP6611646.1"
                     /translation="MQHPVVRFICRTLFYFFILLLLLYLYSYLDIGQGGFIYNEF"
     gene            302..1837
                     /gene="dltA"
                     /locus_tag="AC1PIV_000599"
     CDS             302..1837
                     /gene="dltA"
                     /locus_tag="AC1PIV_000599"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047473 - D-alanine [D-alanyl carrier
                     protein] ligase activity [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HIP6611647.1"
                     /translation="MISSMLERVEHFATENPDYPVYHYLGQLYSYGDLKADSDSLAAH
                     IDSLDLPANSPVLVFGGQEYQMLAIFVALTKAGHPYIPVDSHSALDRIEAILEIAEPS
                     LVFAVADFPLETSLPVLGLSEVEAIFEKKSTYQLIHPVSEDDTYYIIFTSGTTGKPKG
                     VQISHDNLLSFTNWMIRDKEFALPERPQMLAQPSYSFDLSVMYWAPTLALGGTLFALP
                     KELTLDFKTLFAAIQTLPFKIWTSTPSFVDMALLSREFDGEHLPDLTHFYFDGEELTV
                     KTAQKLRERFPKAVIVNAYGPTEATVALSAVAITDEMLVNYKRLPIGYTKPDSPTFIL
                     DEDGQVVPNGQQGEIVVSGPAVSKGYLNNPERTEAAFFQFDGLQAYHTGDLGVMTDEG
                     LLLYGGRMDFQIKYNGYRIELEEVAQHLNKSTYIEAAVAVPRYNADHKVQNLLAYVVP
                     KAGIMEQFDRELELTKVIKQELKERMMDYMMPSKFIYRDSLPLTANGKIDIKGLIAEV
                     NAQ"
     gene            1834..3075
                     /gene="dltB"
                     /locus_tag="AC1PIV_000600"
     CDS             1834..3075
                     /gene="dltB"
                     /locus_tag="AC1PIV_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0070395 - lipoteichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HIP6611648.1"
                     /translation="MMEFFKQLPQLEPYGNPLYFFYLVLALVPIFIGLFFKKRFPLYE
                     TGVSLAFIVLMFTGTKTMQLLSLLAYIIWQTMLIFFYKHYRQRANQSWVFYLIVCLAV
                     FPLTWVKLAPTFSQHGAIFGFLGISYLTFRSVGMVIEMRDGLLTEFSLGSFLRFLLFM
                     PTISSGPIDRYRRFTEDYKQIPERTELLNMLDQTVHYIMMGFLYKFILAYFIGHTLLE
                     PLKAVALDQGGWFNLPTIGVMYLYGFELFFDFAGYSMFAIGISNLMGIRCPINFDQPF
                     KSRDLKEFWNRWHISLSFWFRDFVFMRLVKTLLKHKVFKNRNTVSNVAYLLNMLLMGL
                     WHGVTWYYIAYGLFHALGLIINDAWIRKKKSINLARKKAGQEPLPDNRWTSFAGMFVT
                     FHTVMFSFLIFSGFLDKLWFK"
     gene            3118..3357
                     /gene="dltC"
                     /locus_tag="AC1PIV_000601"
     CDS             3118..3357
                     /gene="dltC"
                     /locus_tag="AC1PIV_000601"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036370 - D-alanyl carrier activity
                     [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HIP6611649.1"
                     /translation="MDVKETILNIIEELFMEDVSEMMDEDLFDAGVLDSMGTVELIVE
                     LESRFNITVPVSEFGREDWNTANKIISGVVELMHA"
     gene            3350..4615
                     /gene="dltD"
                     /locus_tag="AC1PIV_000602"
     CDS             3350..4615
                     /gene="dltD"
                     /locus_tag="AC1PIV_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070394 - lipoteichoic acid metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HIP6611650.1"
                     /translation="MRKQLWQIFGPVICATFLVILTLLFFPSSSRSNFKEEKQDAVAL
                     SYISFKSKYKKNRALGDKNHRFVPFFGSSEWSRFDSMHPSVLADAYQREYTPYLLGQR
                     GAASLTQYFGMQQIGAHLKNSQAIYVVSPQWFSPKGASSKAFEQYFSSDQATHFLQTS
                     AKDDYDRYAAKRFLELKSDCSLTGMFQKVASGKELSKWDREQLNWQAYLLEKQDALFS
                     RFADSGSNLGLVETEAMKLPETFSYDRLSKVANEDGSRSTQSNDFQIDDRFYRNRLQS
                     KIKKLKQSQTKISYLQSPEYNDFQLVLNEFAKHQTDVLFVIPPVNERWMNYTGLNKDM
                     YRATVAKIKYQLTSQGFNHIADLSEQGGIDYFMQDTIHIGWQGWLELDKYVHPFLTEQ
                     QAPVHYQLKKEFLTSEWAAYKGDLNLFLK"
     gene            complement(4704..5819)
                     /locus_tag="AC1PIV_000603"
     CDS             complement(4704..5819)
                     /locus_tag="AC1PIV_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low temperature requirement protein A"
                     /protein_id="HIP6611651.1"
                     /translation="MSEITAKRVSNYELFYDLVFVLATSSLTGLLHGNHIGFKEVTTF
                     ITTNLIIMTLWMNETIYLNKYGERDFLDIFTIIPSMYLIGNMSLNFSNDFAQTALPFN
                     TFLTLSYVIILLQYYLRGRRIGFNEDIKATLQMLATYIVVFAGATLLVIFKLWTNDER
                     MLIVYIIPFLISFFFQKRMSHDPINFPHMVERCQLITIITFGEIVIAIIKNYPLLELP
                     LEGILLFFAMATLFIFYISQTYLTIDHHRKADATVLLYAHLVIVLGLNFFTVAMELFP
                     SHHNDLALPMLIVGNLIFYSGILSTSFYNQQVHQVGRRGLFIYALILLIGNVALLLDG
                     HSNILLFVILNLLSHAMVAYHVIRFGKANHSLLGEDM"
     gene            complement(5892..6848)
                     /locus_tag="AC1PIV_000604"
     CDS             complement(5892..6848)
                     /locus_tag="AC1PIV_000604"
                     /EC_number="1.8.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004364 - glutathione transferase activity
                     [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase family protein"
                     /protein_id="HIP6611652.1"
                     /translation="MGLLQDGKWVDQWYDTKSTGGKFIRSVTQFRNWITPDGQAGPTG
                     EGGFKAESGRYHLYISLACPWASRTLIMRKLKGLEDHISLSVVHPLMLENGWTFEDGP
                     GVIKDTLFNSDYLYQVYLKADPHYSGRVTVPVLWDKKTNTIVSNESAEIMRMFNSAFN
                     DITGNYDDYYPANLQAEIDAMNDFVYPNINNGVYKAGFSTSQAVYEKEVKNLFAALDK
                     LEEHLADKNYLVGNQLTEADIRLFTTLVRFDPVYFGHFKCNIKALVDYPNLWNYTKRI
                     YNHAGIAETVDFDHIKQHYYGSHKTINPTGIVPVGPDLDWTL"
     gene            6987..7703
                     /locus_tag="AC1PIV_000605"
     CDS             6987..7703
                     /locus_tag="AC1PIV_000605"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002282339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_function: GO:0140098 - catalytic activity, acting on
                     RNA [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HIP6611653.1"
                     /translation="MRLDKCLEKAKVGSRKQVKKLFKAQQIKINGQAAQSLSQIVDPE
                     LQTIQVSGKKVALEGSAYYLLHKPAGVVSAVTDQEHQTVIDLISPQDSREGLYPVGRL
                     DRDTEGLVLITNNGPLGYRMLHPSHHVDKVYYVEVNGCLAEDASKFFASGVTFLDGTR
                     CQPADLTVLEASLDHSRATIKLAEGKFHQVKKMFLAYGVKVTYLKRISFGGFELGDLE
                     RGTYRQLTPNEMEHLFTYFD"
     gene            7717..8196
                     /locus_tag="AC1PIV_000606"
     CDS             7717..8196
                     /locus_tag="AC1PIV_000606"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004602 - glutathione peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0043295 - glutathione binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HIP6611654.1"
                     /translation="MSIYDFTVQKQDGTDQSMAEYQGQVLLIVNTAPGCGLAPQYKEL
                     QELYDSYKDNGFVVLDFPCNQFLNQAPGSAEDINQICSLNYGTTFPRFAKIAVNGSEA
                     SPLYRYLKKEKSTLLGGRIEWNFTKFLVDRQGRVVKRYLPTTSPLKLKEDIELYLEK"
     gene            complement(8215..9216)
                     /locus_tag="AC1PIV_000607"
     CDS             complement(8215..9216)
                     /locus_tag="AC1PIV_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HIP6611655.1"
                     /translation="MIRHHNYLKIFTFLLILLFIIFLLSLSIGYSNSSFSDFIDIMSG
                     RASSSTLLIIGRIRLPRIIASIIGGASLALAGLLLQTLTRNPLADSGILGINAGAGLV
                     VALFVGLSSKISPVLLSLMPLFAMMGGGLTIFLVYWIARKKLYGIHPARLIITGVGIS
                     SMLSGIMVSIISQLDDFKMEYIVQWLSGRVNGGDWKTIAIYTPLLLLVWMATFSRSRS
                     LNIMNLNDQTAMALGLHLQRERRITLILATALASLSVILVGNITFVGLIAGHIVRKWL
                     GNDHRVIIPATMIIGSFILLLADTIGRVLLVGTGIPTGIIVSLIGAPYFLWLLKQEG"
     gene            complement(9213..10238)
                     /locus_tag="AC1PIV_000608"
     CDS             complement(9213..10238)
                     /locus_tag="AC1PIV_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002941649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HIP6611656.1"
                     /translation="MNKLVSSRYPKTKPKNIWLVFFIICLSFIAGVYLSLRFGAISYS
                     HQQLIETLKHPLTNSSAQDVIIDLRLPRMVAAILVGAAMAQAGAMMQGITRNPIADPG
                     LLGINAGAGLALIVAYALFGGLHYSQILLICLLGSCLAAGLVFGLAYQVQKGYNQLRL
                     ILSGAMVASLFSAIGQAITIYFDLSTAVIGWQAGGLVQVNWKMLAIIAPLIIIGLILA
                     QLFSHQLTILSLNETVAKNLGQRTLLMTLVLLGIVLLLSASAVALVGSLSFIGLIIPH
                     FIRMFTGKNYKLLLPLTAFAGASFLIWVDLVCRSINPPVETPISAVISIIGLPCFLWL
                     IRKEKHF"
     gene            complement(10252..11181)
                     /locus_tag="AC1PIV_000609"
     CDS             complement(10252..11181)
                     /locus_tag="AC1PIV_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HIP6611657.1"
                     /translation="MKKFLAIFSLFVGLVFLTACSTSSSSTDVELSSMPKIEGITYHG
                     DIPKNPKKVVNFAYSYTGYLLQLGIDVSSYSLDLEKNSPVFGDKLKDVPQLTTADTEA
                     IAAQKPDVILVFSGDDNLETLKEIAPVIEITYGKSDYLKMLTDIGQIFGKEKEAQAWL
                     DQWDKKVTTAKEELKGLIDTSSTFTVMDFFDKNIFLYGNNFGRGGELIYRALGFAAPA
                     KVQEDIINKEGWFGVSQEALPEYVGDYVLVNVNDKTKEAAASLKESDIWKNLPAVKNG
                     HVIEIDYNLFYFSDPMSLDLQIDAFVSEIQKLQ"
     gene            complement(11194..11979)
                     /locus_tag="AC1PIV_000610"
     CDS             complement(11194..11979)
                     /locus_tag="AC1PIV_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIP6611658.1"
                     /translation="MSSIQAENIQVSYDNRIIIDELSTSIPKGSITTIIGANGCGKST
                     LLKALTRIIPVQEGAIYLDGQAISQLPTKEVAKKLALLPQVLEATEGISVYELVSYGR
                     FPHQNGLGHLTDQDREKINWALEVTRTAPYARLPVDDLSGGQRQRVWIAMALAQDTDT
                     IFLDEPTTYLDLNHQLEVLELLKELNQSRQKTIVMVLHDVNLSARFSDYMIAMKEGDI
                     RYHGSVSNMMTTEILRDIFSIEPQLMQVAGQDYPILLTYDLKK"
     gene            complement(12131..13576)
                     /locus_tag="AC1PIV_000611"
     CDS             complement(12131..13576)
                     /locus_tag="AC1PIV_000611"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013990079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HIP6611659.1"
                     /translation="MITIERVLEILKADANFRHIKQNDQTDSTWTDVQFDALSYDSRT
                     VSPMTLFFAKGLAFKKEFLEKAIEAGLAFYVSEINYEVGIPAIIVHDIKQAMSLIAME
                     FHGHPQKQLKLLAFTGTKGKTTAAYFAFNILKQSKKPAMLSTMNTTLDGKTFFKSTLT
                     TPESLDLFAMMAEAVKNGMTHLIMEVSSQAYLVKRVYGLTFDVGVFLNISPDHIGPIE
                     HPTFEDYFYHKRLLMDNSRAVIVNAGMDHFEVVKEQVSSKDHDFYGPTSENQISQSAG
                     FDFTATGKLAGHYDIQLIGGFNQENAIAAGLACLRLGASLEDIHTGIAQTNVPGRMEV
                     LTQQNGAKVFVDYAHNGDSVKKLIDVVLEHQTGKVFLILGAPGNKGESRRKDFGLLLN
                     DYPQIEVILTADDPNREDPAAIAEQIRAHMTRTSNFILDREEAIRTAMSQTSSPKDAV
                     IIAGKGADAYQIVNGEKAAYDGDLEVAKQYL"
     gene            13723..14472
                     /locus_tag="AC1PIV_000612"
     CDS             13723..14472
                     /locus_tag="AC1PIV_000612"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HIP6611660.1"
                     /translation="MFYSYLRTLLTFLLWAINGNIHYHDREKILPQEENYILIAPHKT
                     FWDPVFLGYAAAPKQFIFMAKKELFKDRGFGWWISKCGAFPIDRDNPGMAAIKYPVNM
                     LKKSDRSLVMFPSGSRHSSELKGGVAVIAKSAKVKLMPATYVGPMTIKGLLAGERIDV
                     AFGNPIDVSDIKRMDDAGTAEVTSRIEAEFKRLDDHAASFQTKKKPNILTYIYRIPVL
                     LLVALILGLTYAFSYIASFFWQPSTQLDKNK"
     gene            14535..15197
                     /locus_tag="AC1PIV_000613"
     CDS             14535..15197
                     /locus_tag="AC1PIV_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HIP6611661.1"
                     /translation="MDTIKTYIEMLKEYKWQIALPAVAGLLMATFLIFSQPAKSDQTG
                     LTDFPQTEQASSSQEQTEETSTEESEELSQLTVDVKGAVEKPGLYTLEAGARVNDAVE
                     AAGGLTSQADPKSINLAQKLSDEAVVYVASKDENISVVASTTASSAMSPEEKSTSLVN
                     LNTATEADLQTISGIGAKRAADIIAYREANGGFKSVNDLNNVSGIGDKTMESIRPYVT
                     VE"
     gene            15181..17418
                     /locus_tag="AC1PIV_000614"
     CDS             15181..17418
                     /locus_tag="AC1PIV_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0009290 - DNA import into cell involved in
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HIP6611662.1"
                     /translation="MSRLSKLPCQPVHLAVLAVAAYFAVHSFSLLTMCLLSLVLAVFG
                     VRQGKTVFLKTLPLLTLCGLFFGCQKVQWERAAQSAPEQVTTVQVIPDTIDINGDSLS
                     FRGRADGQNYQVFYKLTSQEEQTYFQNLADLVQLEVEAEVSLPAGQRNFKGFDYQAYL
                     KTQGIYRTVKLTAIKKIVPVQSWNVFDWLSTWRRQALVYVKTNFPAPMSHYMTGLLFG
                     ELDSDFDQMSDLYSSLGIIHLFALSGMQVGFFIDKFRWILLRLGLTKETVDKLQIPFS
                     LVYAGLTGFSVSVVRSLVQKILGNLGLRKLDNFAVTVFICLLILPRFLLTAGGVLTFT
                     YAFLLTVFDFEDLGQVKKAAVESLSISLGILPVLMTYFYAFQPLSILLTFVFSFVFDV
                     LLLPGLSVIFLLSPVVKMTWVNGFFVFMEKIIVWVADLGLRPWILGKPSELVLLLLLV
                     SLFLLYDFHRRKKWLLGLSLVLALLFFITKHPLENEVTVLDIGQGDSIFLRDMRGRTV
                     LIDVGGRVDFAAKEAWQERSRQANAERTLIPYLHSRGVDRIDSLVLTHTDTDHVGDVL
                     EVAKQVQIGRIVVSPGSLTVPDFVATLKKINVPVHVVKVGDRLPIFDSYLEVLYPDGT
                     GDGGNNDSIVLYGRLLETNFLFTGDLEQGELDLIETYPNLPVDVLKAGHHGSKGSSYP
                     EFLDHIGAKIALVSAGENNRYKHPHQETLERFDSRNIQVYRTDQQGAIRFRGWKEWKI
                     ETVRR"
     gene            17435..17560
                     /locus_tag="AC1PIV_000615"
                     /pseudo
     CDS             17435..17560
                     /locus_tag="AC1PIV_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987985.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
     gene            17743..18399
                     /locus_tag="AC1PIV_000616"
     CDS             17743..18399
                     /locus_tag="AC1PIV_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HIP6611663.1"
                     /translation="MSVKDFMTRKVVYISPDTTVAHAADIMREQDLHRLPVIENDKLV
                     GLVTEGTIAEASPSKATSLSIYEMNYLLNKTKVKDVMIKNVITVSGYASLEDAAYLMY
                     KNKVGILPVVDNGQLYGVITDRDIFAAFLHVSGYGEEGVRARFLVENKAGELEKIIRL
                     VADKDYNIVSTVQLATKSGKVVIEVQIDGKVDVEEVRTLFEGAGIQVDSLVPTVAKNI
                     "
     gene            18493..19320
                     /locus_tag="AC1PIV_000617"
     CDS             18493..19320
                     /locus_tag="AC1PIV_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611664.1"
                     /translation="MGHKYKKYKKYGKNNSGLVALLVLLAIGFVMSFWYILLPTGLLI
                     GYFYKREAIQRFLNRDSIKRLQVLALSIRSGYEKHQELLVENGEDKVVLQLRNRLLGQ
                     LFELDQLYQKFGKYLNGYESKEVVDTLQLKYHLKLPEAKTEKNTDTQVSTGGNAVMDE
                     QGMIADLAPEILETYCNIQRDNLVILEKLEKATDKREELTAIHEANMNRFNDILQGYL
                     KIKKSPKDYFNAEERLVQAKSAMEMFDKDLDDTIKQFNEADMKDFEVSLRMMKREEE"
     gene            19326..20597
                     /locus_tag="AC1PIV_000618"
     CDS             19326..20597
                     /locus_tag="AC1PIV_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HIP6611665.1"
                     /translation="MSGFNFDIDQIANNSLSTKDKTTELIQATPTGDNSKVSFLAQLT
                     PEQQTGIRAKAPQLVDNFLANQNVLLDFGKEAVEEVNATVNHILSEQKKIEIPQVDEL
                     LANTNRELNGFVAKYKDISTTAELEKKPGFFQHLFKQTKNDLQEFYFDSQTIEKKMDS
                     MAASVVKQEEVLARNIVSAELLIENNTKSIENLVGVIAFIEATGQEAAQRAKAEQERL
                     AGLQPTTVDYQVASEKLARVTEVANILEQQHSEYMSRLYVAWTTTPQMRNLVKVSSDM
                     KQRLGMLRRNTIPTMKLSIAQLGILQQSIKSSQTADAIVNANNAALQMLADTSKEAIP
                     MMERTAQNPTLSVASVTKLAESLVAQNNGIIAAIDEGRQKRRELEAAIVRSAETINDS
                     VKLRDQKIIAALLEQGKEAQSEAEQPLETNQ"
     gene            complement(20634..21500)
                     /locus_tag="AC1PIV_000619"
     CDS             complement(20634..21500)
                     /locus_tag="AC1PIV_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HIP6611666.1"
                     /translation="MVRLKNILLILLGAGLFAFGLNYLIMPNRLFEGGATGLTLIIYY
                     LFHIQPWIMNIVINIPLFILGWKILGKKTLYLSILGTFSVTFWLAIFEKIHFSINLQQ
                     DLILVSILGGILMGLGLGTIFRAGGTTGGSDIIARIGHKFLPYSIGQIILAVDILILT
                     LIVIVFKDLRTVLYTLMMVAIASKVIDFVTEGGYGSKGVMIVSQKSDQLAQAIDCEIE
                     RGVTFIKAQGFYSKADVNMIYSVIYKSQLQEMKELIHRIDPHAFITITDAHEVLGEGF
                     TLDRDKKPIERH"
     gene            21675..22313
                     /gene="tmk"
                     /locus_tag="AC1PIV_000620"
     CDS             21675..22313
                     /gene="tmk"
                     /locus_tag="AC1PIV_000620"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004798 - dTMP kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006233 - dTDP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HIP6611667.1"
                     /translation="MRNGFFITFEGPDGAGKTTVLQQLLPALQELGPEVVTTREPGGV
                     AIAEEIRNIILNPANTAMDDKTELLLFIAARRQHLKEKILPPLAQGKLLLIDRFIDSS
                     IAYQGFGRGLDIGDIHWLNQFATDGLKPDLTLYFDIDTEEGLARIARNADRDVDRLDM
                     EKADMHRRVRQGYLSILEQEPERFVKIDASQPLEAVVANALAVIKKRFAERT"
     gene            22310..23194
                     /locus_tag="AC1PIV_000621"
     CDS             22310..23194
                     /locus_tag="AC1PIV_000621"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HIP6611668.1"
                     /translation="MKIEELRNLQPYVFQRFVTILEQRRLAHAYLFSGDFASFDIAIF
                     LSQSLFCQEKEGILPCQKCRSCRLIEANEFSDLTVIAPQGNVIKTDTIRELVKNFSQS
                     GFESNKQVFIIRDAEKMHANAANSLLKVIEEPQSAIHIFLLTNQEEAVLPTIKSRTQI
                     IGFPKNIPAMERMLEEEGLLKTQANLLAQLVSSQEEAKKLAENKNFLDLMGQAKKFTD
                     LLLVEPTRAYLQVGILVSLAVEKAEQGRLFDLLSLILSEKMMESANVREKMDAVLKAK
                     KMWQANVSLQNSLEYITL"
     gene            23214..23531
                     /gene="yabA"
                     /locus_tag="AC1PIV_000622"
     CDS             23214..23531
                     /gene="yabA"
                     /locus_tag="AC1PIV_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HIP6611669.1"
                     /translation="MDKKEIFDALDDFSQNLLTTLAEVDAIKKHLQGVIDENTTLRLE
                     NSKLRERLEKEDKTGHKSSNFGKENLENIYEDGFHICTFSYGQRRDNDEPCMFCVELL
                     NRD"
     gene            23533..24396
                     /gene="rsmI"
                     /locus_tag="AC1PIV_000623"
     CDS             23533..24396
                     /gene="rsmI"
                     /locus_tag="AC1PIV_000623"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HIP6611670.1"
                     /translation="MKVQKSFKGQTSFGTLYLVPTPIGNLQDMTFRAVQILKEVDIIA
                     AEDTRNTGLLLKHFEVETKQISFHEHNAHEKIPVLIDWLKSGQSIAQVSDAGLPSISD
                     PGHDLVGAAIAEDIPVVALPGASAGITALIASGLAPQPHIFYGFLPRKSGQQKEFFQE
                     KKTYPETQIFYESPYRVADTLENMLTVYGDRQVTVVRELTKLYEEYQRGSISELLEYL
                     EENPLKGECLIIVEGAGEEVYPSADEVDLKAEVEREIASGIKPNQAIKEVAKRYQLKK
                     QEVYDIYHGLG"
     gene            24866..25957
                     /gene="serC"
                     /locus_tag="AC1PIV_000624"
     CDS             24866..25957
                     /gene="serC"
                     /locus_tag="AC1PIV_000624"
                     /EC_number="2.6.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0004648 -
                     O-phospho-L-serine:2-oxoglutarate aminotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006564 - L-serine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoserine/phosphohydroxythreonine
                     transaminase"
                     /protein_id="HIP6611671.1"
                     /translation="MTIYNFSAGPAVLPKPVLERAQAEFLDYNGSGMSVLEMSHRSKD
                     FDDIIKGAEATLRELMAIPDNYKVIFLQGGASLEFTMIPLNFAQGKKAYYLVGGSWGK
                     KAYTEAVKLSKTIAFEPILLGSTEDITYAELPTFDKNDIDPTAAYVHLTTNNTIEGTA
                     VYDIPDTNGVPVIADMSSNILAARYNVEDFAMIYAGAQKNIGPAGVTVVIVREDFLND
                     QPMLSSMLDYRIQAENDSLYNTPPAYSIYISKLVFEWVKEIGGVDEMEKINREKSGLL
                     YDYIDQSNFYTNPVRKKEERSVANIPFVSPSEELDAKFVKEATAAGFKNIKGHRSVGG
                     MRASLYNAFPRQGVVELIEFMKKFAVENA"
     gene            25957..26514
                     /locus_tag="AC1PIV_000625"
     CDS             25957..26514
                     /locus_tag="AC1PIV_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIP6611672.1"
                     /translation="MEIRLAHPNEMEAIVNILEDARAFLATSGINQWQGEYPNKENIF
                     DDILSGRGYVGLVDGKVAAYAAVHRGQEAEYEAIYEGKWQHNHPVYTTFHRIAAADEF
                     RGQGIIQTFLQGLIEGQKGPDFRCDTHEQNKTIQHILKKLGYVYCGKVPIDGERLAYQ
                     KIKQKSERSLYQEISEDDRWLLGNN"
     gene            26568..27749
                     /locus_tag="AC1PIV_000626"
     CDS             26568..27749
                     /locus_tag="AC1PIV_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HIP6611673.1"
                     /translation="MVFSVRTFNNINQIGLKELGNKFQIDGDHAANPDAFIIRSENLH
                     GFDFPENLKAIARAGAGTNNIPIEEATEKGIVVFNTPGANANAVKEAVIASILLSARD
                     YIGATAWANTLSGDDVPKQVEAGKKQFAGTEISGKTLGVIGLGAIGARIANDARRLGM
                     NVLGYDPYVSVETAWTISSHVKRVDDLKEIFTNADYITVHVPLTDKTRGLFNADSFCQ
                     MRKGTTLINFARGELVNNADLFEAIEAGVIKNYITDFGTEEVLNKDNIIVFPHVGGST
                     EEAELNCAIAAGQTIRRFMETGEIINSVNFPNVKQFLDAPYRITLINKNIPNMVATIT
                     TAVSELGINIDNIINKSKGDYAYTLLDLDEADKVKIEQLVAKFEATDAIVKVRVIQNK
                     N"
     gene            27752..28258
                     /locus_tag="AC1PIV_000627"
     CDS             27752..28258
                     /locus_tag="AC1PIV_000627"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HIP6611674.1"
                     /translation="MLYKQVYHSPLGPMSLIASDKGLRGAWFEGQKYFERGLNEKAIL
                     ASHPILDQTARLLDQYFSGDQVDFSNLPLEAVGTNFQEHVWQLLKIIPMGQTTTYGQL
                     AQQLGLRSGQAVGGAVGRNPYSIIVPCHRVLNQKGQLTGYAGGLDKKIWLLRHENPEF
                     EVKDDFIL"
     gene            28242..28595
                     /locus_tag="AC1PIV_000628"
     CDS             28242..28595
                     /locus_tag="AC1PIV_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HIP6611675.1"
                     /translation="MILFYEYPKCSTCRAAKAELKSLGLEFEAIDIKSTPPSAEEIKA
                     WMEATGLELKKYFNTSGNSYRELGLKDKFDSLSLEQALNLLANDGMLIKRPLLIQDGK
                     ILQIGYRTKYENLGL"
     gene            complement(28612..29511)
                     /locus_tag="AC1PIV_000629"
     CDS             complement(28612..29511)
                     /locus_tag="AC1PIV_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HIP6611676.1"
                     /translation="MDHKIIERKSLTVSSVVNGLSGLAGIAVYIMTDLNALLLDGVFS
                     LIAFISSLVAVYISKNSHRKTETFPQGLYFLEPLYAIMKSLATLLLLVFAVLETSATA
                     FAYFVHGIGHQMTTGPVLPYTITMFFVCMGLYLYNRHMSAKVNHLSTIILAEAKGNLV
                     DGLISGAIGIAILLLYLVPINSWFGFLHYTGDFFLTLALAIISFKEPWNLLVASFKEL
                     ANGTIHFPEIHDSIYQLLEPYLKEDSNDVEIHIFKQGMKIRVKINLHNVHHEIIQKLL
                     EDKPQMLYLLKKHHEYISIEYAL"
     gene            complement(29698..30525)
                     /locus_tag="AC1PIV_000630"
     CDS             complement(29698..30525)
                     /locus_tag="AC1PIV_000630"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HIP6611677.1"
                     /translation="MKLISWNIDSLNAALTAESPRALLSRAVIDTLVTEDADIIAIQE
                     TKLSDKGPTKKHLEILESYFPGYANTWRSSVEPARKGYAGTLFLYKNHLTPTITFPEI
                     GAPTTMDSEGRIITLEFDDFYVTQVYTPNAGDGLKRLADRQIWDVQYADYLAKLDSHK
                     PVLATGDYNVAHKEIDLANPASNRQSPGFTDEERQGFTNLLAKGFTDTFRHLHGDVLN
                     AYTWWAQRSRTSKINNTGWRIDYWLVSDRIADKVSKSDMIDSGARQDHTPIVMEISF"
BASE COUNT         9059 a         5720 c         6935 g         8902 t
ORIGIN      
        1 tttagtgaaa aaagaaataa attgacaaaa ttatggtaaa atataggttg atttaaaatt
       61 aatcatctaa tgaatggaat gagttcgaag taagtcaaga ttgactagac attgtattta
      121 aagcaattcg caggaataag agatggaagg agatagaaca tgcaacatcc agttgtacga
      181 tttatctgta gaaccctgtt ctattttttt atattgttac tacttttgta tctgtatagt
      241 tatttagaca ttggacaggg aggatttatc tataatgagt tttaaagagg agagtataaa
      301 aatgattagc agtatgttag agcgggtaga gcattttgcg acagaaaatc ctgactaccc
      361 tgtttaccat tatctaggac agttgtatag ttatggggat ttaaaggcag attcagattc
      421 tttagcagcc catattgata gtttggattt accagcaaac tctcctgtcc ttgtttttgg
      481 cggacaggag taccagatgt tggcaatctt tgtagcctta accaaggctg gccatccgta
      541 tatccctgta gatagtcatt ctgctttgga tcggattgaa gctattctgg aaatagcaga
      601 gccgagtttg gtgtttgcgg tagcagactt tccgctagag acaagtttgc cagtgcttgg
      661 tttgtctgaa gttgaagcca tttttgagaa gaagtcgact tatcagttga tacatcctgt
      721 aagcgaagat gatacctact atattatctt cacttctggg acaacgggta aaccaaaagg
      781 agtgcaaatt tcgcatgaca atttgctcag ctttactaac tggatgataa gggataagga
      841 gtttgcgcta ccagagcgac cgcaaatgtt agctcaacct tcctattcgt ttgacttgtc
      901 ggttatgtat tgggctccga cgcttgccct tggtgggacc ttatttgctc taccgaaaga
      961 gttgactttg gattttaaga ctttatttgc agctattcaa actttgccat ttaagatttg
     1021 gacttcgaca ccatcatttg tagatatggc tttgctatct cgtgagtttg atggggaaca
     1081 tttaccagat ttgacgcatt tctattttga cggagaggag ttaactgtaa aaacagctca
     1141 gaagctccgc gaacgttttc caaaagctgt gattgttaac gcttatggac cgaccgaagc
     1201 tacagtcgcc ttatcagcag ttgccatcac tgatgagatg ctggtgaatt ataaacgttt
     1261 gccgattggt tataccaaac cagactcgcc aacttttatt ttggatgagg atggtcaagt
     1321 agtaccgaat ggtcaacagg gagaaattgt tgtatcaggt cctgctgtct ctaaaggata
     1381 tttgaataat cctgagagaa ccgaggcggc atttttccag tttgacggct tacaggccta
     1441 tcatactggg gatttgggtg taatgacaga tgaaggtctg ttactctatg gtgggcgtat
     1501 ggatttccaa attaaatata atggttatcg tatcgagttg gaagaagttg cccaacacct
     1561 aaataaatca acctatattg aggctgcggt ggctgttcca cgttataatg ctgaccataa
     1621 agtgcaaaat ctgttagctt atgttgtccc taaagcaggg attatggagc agttcgatcg
     1681 agagttggag ttaaccaagg tcatcaagca ggagttaaaa gaacggatga tggattatat
     1741 gatgccttcg aagtttattt atcgagacag tcttcctttg actgcaaatg ggaagattga
     1801 tattaagggg ttgatcgctg aggtgaatgc tcaatgatgg agttttttaa acagctacct
     1861 cagttagagc cttatggaaa tccattgtac tttttctatc tagtcttggc gctagtacca
     1921 atttttatag gactcttttt taaaaaacgt ttccccttgt atgaaacagg tgttagttta
     1981 gccttcattg tcttgatgtt tacaggtaca aagacaatgc aattgctgtc tttattggcc
     2041 tatattattt ggcagacaat gttgattttt ttctacaagc attatcgtca acgggcaaat
     2101 caaagctggg tcttctatct aatcgtgtgt ttagctgttt ttccgttgac ttgggtaaag
     2161 ttggcaccga cttttagtca gcatggggca attttcggtt ttttaggtat ttcttattta
     2221 acgtttcggt cggtcggaat ggtgattgaa atgcgggacg gtttactaac ggaatttagt
     2281 ttgggaagtt ttttgcgatt tttgctattt atgccaacta tttcgagtgg ccctattgat
     2341 cgttatagac ggtttacgga agattacaaa caaattcctg agcgaactga gttattaaat
     2401 atgctcgatc agactgtgca ttatattatg atgggcttct tatataagtt tattctagcc
     2461 tattttatcg ggcatacttt actggagcct ttaaaggcag tagccttgga tcaaggtgga
     2521 tggtttaact tacctactat tggagttatg tatctttatg gttttgaatt attctttgac
     2581 tttgcaggct attccatgtt tgccataggt atttccaatc ttatgggtat tcgctgccca
     2641 attaactttg atcaaccgtt caaatcgcgt gatcttaagg agttttggaa tcgatggcat
     2701 atcagcttat ctttttggtt ccgtgatttc gtcttcatgc gtctggttaa gactttgttg
     2761 aaacataagg ttttcaaaaa tcgaaatacg gtatctaatg ttgcctatct gctaaatatg
     2821 ctcttgatgg gcttgtggca tggtgtaaca tggtattata ttgcatatgg tctctttcat
     2881 gctttggggt tgatcatcaa tgatgcttgg attcgtaaga agaaatcaat taatttagct
     2941 cgaaaaaaag ctgggcaaga accattgccg gataatcgtt ggacgagttt cgctggtatg
     3001 tttgtgacct tccatacggt catgttctct ttcttgatat tttcaggatt tttagataaa
     3061 ttgtggttca agtagacaat aggtaacgat tgtatgaatc gtagaaagga ataaaaaatg
     3121 gatgtaaaag aaacaatatt gaatattatc gaagaattat ttatggaaga tgtatctgaa
     3181 atgatggatg aagacctatt tgatgcgggt gttttggata gtatgggaac tgtagaactt
     3241 attgtggagt tagaaagtcg ttttaatatt acagttccag tttcagagtt tggtcgtgaa
     3301 gattggaata cagctaacaa aatcatttct ggtgttgtgg agttgatgca tgcgtaagca
     3361 attgtggcag atttttggac ctgtgatttg tgcaacgttt ttagttattc tcacgttgtt
     3421 gtttttcccg agttcttctc ggtcaaattt caaagaagaa aaacaagatg cagtagcatt
     3481 gtcttatatt agttttaaga gcaaatataa gaaaaatagg gctctgggag ataaaaatca
     3541 tcgttttgtt cctttctttg ggtcaagtga atggtcacgt tttgatagta tgcatccgtc
     3601 agtgttggca gatgcctatc agagagagta tactccctat ttgttaggac aacgtggtgc
     3661 agcttcgctg acacaatatt ttggcatgca acagattggg gcacatttaa aaaatagtca
     3721 ggctatctat gttgtttctc ctcaatggtt ttcacccaaa ggggcatcat ctaaggcatt
     3781 tgaacaatat tttagtagtg atcaagccac tcattttctg caaacaagtg ctaaggatga
     3841 ctatgataga tatgcagcaa agcgtttctt agagcttaaa tcagactgta gtttgacagg
     3901 aatgtttcaa aaagtagcta gtggtaagga attgtcgaaa tgggatagag agcagttgaa
     3961 ctggcaagcc tatttattag aaaagcaaga tgccttattt agtcgctttg ctgattctgg
     4021 tagtaattta ggattggtag aaacggaagc gatgaaactt ccagagactt tttcctatga
     4081 ccgcttgagt aaagtggcta atgaggacgg gagtcgttct actcaatcaa atgatttcca
     4141 aattgatgat aggttttata gaaatcgtct tcagtcaaaa atcaaaaaac tcaaacaatc
     4201 ccagacaaaa atatcttatc tgcaatcacc ggagtacaat gattttcagc tggttttgaa
     4261 tgaatttgct aaacatcaga ctgatgtgct atttgtaatt cccccggtta atgaacgttg
     4321 gatgaactac actggtctca ataaagatat gtatcgggca acagtagcaa agattaagta
     4381 ccagttgacc agtcaaggtt tcaatcatat tgctgatttg tcggagcagg gggggataga
     4441 ttattttatg caagatacga tccacatcgg ttggcaaggc tggctggagc ttgataagta
     4501 tgtccaccca ttcttgacag aacaacaagc acctgttcat tatcagttaa aaaaagaatt
     4561 tttaacttcc gaatgggctg catataaggg agatttaaac ttatttttga aatagttaga
     4621 tacagttata ataaaaagca agaaggcttt gaattaggaa gtctccttgc ttttttgttc
     4681 ttttactgta ataaactgaa tgattacata tcttctccca acaaactgtg gttggctttg
     4741 ccgaagcgaa taacatgata ggcaaccata gcgtgtgaga gcaggtttaa gataacaaat
     4801 agtaggatat ttgaatgacc atccagcaat aaggcaacat ttccaattag taaaatgaga
     4861 gcatagatga acagccctct cctgccaact tgatggactt gttgattata gaaggaggtc
     4921 gaaaggatac cactatagaa gataaggttt cctacaatca gcatgggcaa ggccaaatca
     4981 ttatgatgac tagggaaaag ctccattgcc actgtgaaga aattcaagcc aagaacaatt
     5041 accaagtgag cgtatagcag aacagtcgca tctgccttgc ggtgatggtc gatagtgaga
     5101 taggtttgag aaatatagaa gatgaacaga gtcgccattg cgaagaagag gaggattcct
     5161 tccaaaggaa gttctagaag cgggtaattt ttgataatag ctatgacgat ctcaccgaaa
     5221 gtgataatgg taatcagctg gcaacgttcc accatgtgtg ggaagttgat ggggtcatga
     5281 ctcattctct tttggaagaa gaaggaaatc aagaagggaa taatatagac aatcagcatc
     5341 cgttcatcat tggtccatag cttgaagatg accaacaagg ttgcaccggc aaagacaaca
     5401 atataagtcg ccagcatctg caaggttgcc ttgatgtcct cattaaagcc aatccgtctt
     5461 cctcttaagt aatattgtag gagaataatg acataagaca aggttaaaaa ggtgttaaat
     5521 ggcagagctg tttgtgcaaa atcgttgcta aaattaagtg acatatttcc aatcagatac
     5581 atggatggaa taatggtgaa aatatccaga aaatcccgtt cgccgtattt attgagatag
     5641 atggtttcat tcatccacaa ggtcataata atcaagtttg tagtgataaa tgttgtaact
     5701 tccttgaaac cgatgtggtt cccatgtagc aagccagtca gtgaagaagt ggccaggaca
     5761 aagaccagat cataaaataa ttcataattg gaaacacgtt ttgctgtaat ttcagacatg
     5821 tcaatctcct tttaaaaaaa tctgaaatat tataccatac gaaaagggag gatgtcatct
     5881 ctctttatat cttatagtgt ccagtccaag tctggtccga ctgggacaat acctgttggg
     5941 ttaatggttt tgtggctacc gtagtagtgc tgtttgatat ggtcaaagtc aaccgtctct
     6001 gcaatgccag catggttgta aatccgtttg gtataattcc acaagtttgg ataatcaacc
     6061 aaggccttga tattgcattt gaaatgccca aagtaaacag gatcgaatcg caccaaagtg
     6121 gtaaagagtc gaatatcagc ctctgtcagc tgattgccaa ccagatagtt cttatcagcc
     6181 aaatgctctt ctagtttatc caaggcagca aaaaggttct tgacctcttt ttcatagact
     6241 gcctgactgg ttgaaaaacc tgccttgtag actccgttgt tgatgtttgg atagacaaaa
     6301 tcattcatgg catcaatctc ggcttgcagg tttgctggat aatagtcatc gtaatttcca
     6361 gtaatatcat taaaagcaga gttaaacatg cgcatgattt cagccgattc attgctgacg
     6421 atggtattgg ttttcttatc ccacaagaca ggcacggtca cccgaccaga atagtgtgga
     6481 tcagccttca aatagacctg atagagataa tcgctgttaa agagggtatc cttgataaca
     6541 ccaggaccat cttcaaatgt ccagccattt tctaacatga ggggatgaac gacagacaag
     6601 gaaatatggt cttccaagcc cttcaatttt cgcataatca aggtccgact agcccaagga
     6661 caagccagag aaatatagag gtggtagcga ccagactcag ccttaaaacc accctctcct
     6721 gttgggcctg cctgtccgtc tggcgtaatc cagttgcgaa attgtgtgac gctacgaata
     6781 aacttaccgc ctgttgactt ggtgtcatac cattgatcca cccatttgcc atcttgtaaa
     6841 agtcccatga attttctccc ttactgaaaa aatgggaaat ccaataggat gattggattt
     6901 cctttgtaaa aaaatatatc actaactagt attataaact tttttcaaaa agagtcaagc
     6961 tatatgattt gtgataaaat agtcccatga gattggacaa atgtttagag aaagccaaag
     7021 ttggctcgcg taagcaagtt aaaaaacttt tcaaagccca gcaaatcaag attaacggac
     7081 aagcagctca aagcctaagc cagattgttg acccagagtt acaaactatc caagtttcgg
     7141 gtaaaaaagt tgccttagaa ggttccgcct attatttgct ccataaacca gcaggagtcg
     7201 tttctgccgt gacagaccag gagcatcaga cagtcatcga cttgatttct ccgcaagaca
     7261 gtagggaagg tctctaccca gtcggtcgcc tggacaggga taccgaaggc ctagtcctca
     7321 ttaccaacaa tggtccgctc ggttatcgca tgctccatcc cagccaccat gtggacaagg
     7381 tctactatgt ggaggtaaat ggatgcttgg ctgaggatgc ttcaaaattt tttgcctcag
     7441 gtgttacttt cttggatgga acacggtgtc agcctgcaga tttgactgtc ttggaggctt
     7501 ctttggacca tagcagagcg accatcaagc tggcagaagg taagtttcat caggtcaaaa
     7561 agatgttttt agcctatggt gtcaaggtca cttatctcaa gcggatttcc tttggtggtt
     7621 ttgaactggg ggatttggaa cgaggtacat acagacaact cacaccaaat gaaatggaac
     7681 atttattcac ttattttgac tagaggagga tatataatga gcatttatga ttttacagta
     7741 caaaaacaag atggcacaga ccagtccatg gctgagtatc aaggacaagt tttacttata
     7801 gtcaatacag cgccaggttg tggattggca ccacaataca aggaactaca ggagctatat
     7861 gatagctata aagacaacgg ttttgtagtg ttggatttcc cttgtaatca atttttaaat
     7921 caggctcccg gttctgcgga agacatcaat cagatctgta gcttgaatta tggtacaact
     7981 tttcctcgtt ttgctaaaat tgctgtgaat ggatctgaag ctagtccgct atatcgctat
     8041 cttaagaaag aaaaatcaac cttattagga ggtcgaattg agtggaattt taccaagttt
     8101 ttggtggata gacaagggcg tgtggtcaaa cgatatttac caacaactag tccattaaaa
     8161 cttaaagagg atattgaact ttacctagaa aaataacaag aaggctggag tcatctagcc
     8221 ttcttgtttt agtaaccaca gaaaataggg agcgccgata agggagacaa tgatgccggt
     8281 tgggatgcct gttccgacaa gtagtactcg tcctatggta tccgctagaa gtagaatgaa
     8341 gcttcctatt atcatagtag ctggaatgat gacacgatgg tcatttccta accatttgcg
     8401 cactatgtga ccagcaatga gaccaacgaa ggtgatatta ccaactaaaa tgacactaag
     8461 agaggctagg gcggtagcca atatcaaggt aatccgcctt tcacgctgta agtggagccc
     8521 caaagccatg gctgtctggt cgtttagatt cataatattg agtgagcgac ttcgactaaa
     8581 cgttgccatc cacaccaata gaagaagagg agtatagatt gcgatagttt tccaatctcc
     8641 accatttact cgaccgctga gccactggac aatgtattcc atcttaaagt catctaattg
     8701 gctgatgatg ctgaccatga taccagacag catgctcgaa attccaactc ccgtgataat
     8761 taagcgtgca ggatggatac cgtacagctt cttacgtgca atccagtaaa ctagaaaaat
     8821 ggttaatcca ccgcccatca tagcaaatag aggcatgaga ctcaataaga cagggctgat
     8881 ttttgaagag agaccgacaa atagtgccac aacaagacca gctcctgcgt tgattcctaa
     8941 tattccagaa tctgccagag gattgcgggt caaagtttgt agcaacaaac ccgccaaagc
     9001 cagagaagcc cctccgataa tggaggcgat tattctaggt aagcgaattc gtccaatgat
     9061 aagtagagtc gatgaactgg cacgcccact catgatgtcg atgaaatccg aaaaggatga
     9121 attgctatag ccgatagata aggaaagtag gaaaatgata aataaaagga ttagcaggaa
     9181 tgtgaatatt tttagatagt tgtgatgtct tatcaaaagt gtttctcctt tctaatcaac
     9241 cataggaagc aagggagacc aatgatactg atgactgcgc taatgggagt ttcaacaggt
     9301 ggattgatag aacggcaaac caaatctacc cagatgagga aactagcccc tgcaaaggca
     9361 gttaatggca agagtagctt gtaatttttc cctgtaaaca tgcggataaa gtgaggaata
     9421 atgagcccga taaaagaaag tgagcccaca agagctaccg cagaagctga gagtagaagg
     9481 acaattccca acaaaaccaa ggtcatcagt aaggttcgtt gacctagatt tttagcaacg
     9541 gtttcgttga gactcaggat ggtcagctga tgcgaaaaga gttgagcaag gatgaggccg
     9601 atgatgataa gaggagcaat gatggccagc atcttccagt ttacctgtac caatccccca
     9661 gcttgccagc caatcactgc agttgataaa tcaaagtaga tagtaatagc ttgaccaata
     9721 gcagaaaata gacttgctac catggcgcca gataaaatta aacgtagttg attgtagcct
     9781 ttttgcacct gataagctag accaaagact aggccggctg ccagacagga gcccagtaaa
     9841 catattaata aaatttgact gtagtgcaaa ccaccgaaca gagcataggc aacaatgaga
     9901 gcaagtcctg ctccagcatt gattcctaat aagccaggat cggcaatcgg attgcgtgta
     9961 attccttgca tcattgcccc agcttgggcc atggcagctc ctaccaagat ggcggctacc
    10021 attctaggca agcgtaaatc gatgataaca tcctgagcgg aagaatttgt cagtggatgc
    10081 tttagggttt ctatcagttg ttggtggcta taagaaatag ctccaaagcg taaactaaga
    10141 tagactccag ctatgaaaga aagacagatg atgaaaaaaa caagccaaat attctttggc
    10201 tttgttttgg gataacgaga acttactagt ttgttcatat atccagtcct tttactgaag
    10261 tttttgaatt tctgagacaa aggcgtcaat ttgtaaatct aaagacatcg gatcggagaa
    10321 gtagaagagg ttatagtcta tctcgatgac gtgaccattc tttacagcag gtagattttt
    10381 ccaaatatca ctttctttga gagaggcagc tgcttctttt gttttatcat tgacgttaac
    10441 aaggacatag tcgccaacat attctggaag agcttcttga gataccccaa accagccttc
    10501 tttattgatg atgtcttctt gaacctttgc aggagcggca aaaccgagag cgcgatagat
    10561 taattctcca ccacgaccaa agttattacc ataaaggaag atgttcttat cgaagaagtc
    10621 catgacagta aatgttgaac ttgtatcaat caatcctttc aattcctctt ttgcagtagt
    10681 aactttctta tcccattgat ctaaccaggc ttgtgcttcc ttttcttttc caaaaatctg
    10741 accaatatct gtcagcattt tcaagtagtc actctttcca taagtgattt caataactgg
    10801 agcaatttct ttcagtgttt ctaagttatc atcaccagaa aatactagaa tgacatctgg
    10861 cttttgtgcg gcaatcgctt ctgtatctgc tgttgttaat tgtggaacat cctttagttt
    10921 gtctccaaag acgggactat ttttctctaa atctagacta tagctagata catcaattcc
    10981 taattgtaag agatagcctg tgtaagagta agcaaagttg acaacttttt taggattttt
    11041 tggaatgtca ccgtggtaag taatgccttc aatctttggc atgctagaca gttctacgtc
    11101 tgttgaagag gaagaggtag agcaagctgt taagaaaacc agcccaacaa ataaactaaa
    11161 aatagctaaa aactttttca ttttttctcc ttattatttt tttaaatcgt aagttagcaa
    11221 aatagggtaa tcttgaccag caacctgcat caattgaggt tcaatgctaa aaatgtccct
    11281 aagtatctca gttgtcatca tattggacac agatccatgg tagcgaatat ctccctcttt
    11341 catggcaatc atataatctg aaaatcgagc tgataaattg acatcgtgaa ggaccatcac
    11401 aatggttttc tgtcggcttt gattcagttc ttttaaaagt tctaagactt ccaattgatg
    11461 attgagatca agataggttg ttggttcatc taagaaaatg gtatccgtat cttgggcaag
    11521 tgccatcgca atccaaaccc gttgcctctg accacctgat aaatcatcaa ctggtaacct
    11581 agcgtaggga gcggtccggg tgacttccaa ggcccagttg attttctctc tatcctgatc
    11641 agtgagatgt cccagcccat tttgatgcgg aaagcgacca taggagacca gttcataaac
    11701 ggaaatccct tctgtcgctt ctaagacctg agggagcagg gccaattttt ttgcaacttc
    11761 tttggttggc agttgtgaaa tggcttgtcc atctagatag atagcccctt cttgaacagg
    11821 aataatcctt gtcaacgcct taagcaaggt cgattttcca cagccattgg caccaatgat
    11881 tgtcgttata cttccttttg gaatacttgt tgataattca tcaataataa tccgattgtc
    11941 gtaagagact tggatatttt ccgcttgaat cgaagacaca aactcctcct ttccagaata
    12001 tgattcatta ataatttgtt ccgaccagta ttatatcaaa aaaatttacc aaaacaaaga
    12061 gttttctgaa aattttaatt taatgagaat cgttataaaa aagtccttgt ttgtgaacaa
    12121 ggaccgtatg ttacaaatat tgttttgcta cttccaaatc accgtcatag gcggcctttt
    12181 cgccgtttac aatctggtag gcatcggctc ccttgcctgc gatgatgacg gcatctttcg
    12241 gagagcttgt ctgactcatg gctgtgcgaa tggcttcttc ccggtccaag ataaagttgc
    12301 ttgtacgggt catgtgggca cggatttgtt cagcaatagc agctgggtct tcacggttgg
    12361 ggtcatcagc tgtcagaatc acctcaatct gcggatagtc attgagcaga agaccgaagt
    12421 ctttgcggcg actttctccc ttgttaccag gagctcccaa aatcaaaaat accttgcctg
    12481 tctggtgctc taagacgaca tcaatcagct tcttgacact atcgccgtta tgggcgtagt
    12541 ccacgaatac cttggcaccg ttttgctggg tcaggacttc catacgacca gggacattgg
    12601 tttgggcaat ccctgtgtga atatcttcca gacttgctcc caaacggaga caggccagtc
    12661 ctgctgcgat ggcattttct tggttgaagc caccgatcag ctggatgtcg taatggccag
    12721 ccaatttgcc agtcgctgta aaatcaaaac ctgctgactg actaatctgg ttttcagaag
    12781 tcggcccata aaagtcatgg tctttggagc tgacttgctc tttcacgact tcaaaatggt
    12841 ccattccagc attgacaatg accgctctgc tattgtccat caaaaggcgc ttgtgataga
    12901 aatagtcctc aaaggtcgga tgctcaatgg ggccgatgtg gtcggggctg atgttgagga
    12961 agacaccgac gtcaaaggtc agcccgtaaa cccgcttgac caagtaagcc tggctggaca
    13021 cctccataat caagtgggtc atgccgttct tgaccgcctc cgccatcatg gcaaagaggt
    13081 ccagactttc gggcgtggtc agggtggact tgaagaaggt cttaccgtcc agcgtggtgt
    13141 tcatggtcga aagcatggca ggtttcttgc tctgtttaag gatgttaaaa gcaaaataag
    13201 ccgccgttgt tttacccttg gtgccggtga aggccaggag tttgagctgt ttctggggat
    13261 gaccatgaaa ttccatggca atcaggctca tagcctgctt gatgtcgtgg acgatgatag
    13321 caggaatgcc gacctcatag ttgatttcag acacgtaaaa agccagtccg gcctcgatag
    13381 ctttttccag aaattccttt ttaaaggcca aacccttggc aaaaaagagg gtcattgggc
    13441 taacagtccg gctgtcatag ctgagagcgt caaactggac atccgtccat gtgctgtcag
    13501 tttggtcatt ctgtttgata tggcggaagt tagcatccgc cttcaatatt tctaatacac
    13561 gttcaattgt aatcatgctt ctattgtaaa cctatcgagg atatttgaca agtctgggat
    13621 atgtaaatag tgggtatttt gaccgtaaat ttgaatgaat atgacatttc gccctgaagc
    13681 aaatttgtgc tataatagga gggattgaaa aaggagaagt ttatgtttta ttcttatcta
    13741 cgaacactat taacattctt gttgtgggcc atcaatggca atattcacta tcatgataga
    13801 gagaagattt tgccacagga ggaaaattat attcttatcg ctccgcacaa aaccttctgg
    13861 gatccagtct ttcttgggta cgcagctgct cccaagcagt tcatctttat ggctaaaaaa
    13921 gaactcttca aagaccgcgg ttttggttgg tggatttcaa aatgtggagc ctttccaatt
    13981 gaccgtgaca atcctggcat ggcagccatc aagtatccag ttaacatgtt gaaaaaaagt
    14041 gaccgttcgc tggtcatgtt tccttctgga agtcgtcatt catctgagct aaaaggtggt
    14101 gtggcggtca tcgccaagtc agccaaggtc aaactcatgc cagctaccta tgtgggtccc
    14161 atgactatca aggggctctt agctggtgag cgaatcgatg tggcttttgg aaatcctatc
    14221 gatgtttcgg acatcaagcg tatggatgat gcaggtacag cagaagtaac tagccgaatt
    14281 gaggctgagt tcaaacgctt agatgaccat gcggcatctt tccaaaccaa gaaaaaacca
    14341 aatatcttga cttatatcta tcgtatccca gttcttttgc tggttgctct tatcttggga
    14401 ttgacctatg cctttagcta tattgccagc ttcttctggc aaccaagtac tcagttggat
    14461 aaaaataagt aaatgaaact cgcagcttgc gggttttttg tattttttac gaactatata
    14521 ggtggaggta atttatggat acgattaaaa cttatataga aatgcttaaa gaatacaagt
    14581 ggcaaattgc tctgccagca gtggctggct tgctaatggc gacgttttta atattcagcc
    14641 aacctgctaa gtctgatcaa acaggactga cagattttcc tcaaaccgag caagcttcta
    14701 gcagtcagga gcagacggag gaaaccagta cagaagagag tgaggagctc agccagctaa
    14761 ccgttgatgt caaaggagcg gtggaaaagc ctgggttata tactttagaa gctggtgcgc
    14821 gtgtcaatga cgcagttgaa gcagctggcg gcttgaccag tcaggcagac cccaagtcta
    14881 tcaatctggc tcagaagctc agcgatgagg cggtggtcta tgtagccagc aaggacgaaa
    14941 acatctcggt ggtggccagc acgactgcca gctctgctat gtctccagaa gaaaaaagca
    15001 ccagtctggt caatctgaat acggcgactg aggcggactt gcagaccatt tcgggtatcg
    15061 gtgccaagcg ggcggcggac attatcgcct atcgtgaggc aaacggtggc ttcaagtcgg
    15121 tgaacgacct caacaatgtt tcgggcattg gcgacaagac catggaaagc attcggcctt
    15181 atgtcacggt tgagtaagct cccctgccag cccgttcacc tggcagtctt ggcggtggca
    15241 gcttactttg cagtccactc tttttccctc ttgacaatgt gcctgctcag cttggtgtta
    15301 gctgtctttg gtgttcggca aggtaagaca gttttcctca aaacgctgcc gcttctaacc
    15361 ctgtgtggtc tctttttcgg atgccaaaag gtccaatggg agcgggcagc tcagtcagcc
    15421 ccagagcaag tgacgactgt gcaggtcatt ccagatacca tagacatcaa tggcgacagc
    15481 ttgtcttttc gtggtcgggc tgatggacaa aactatcagg ttttctacaa attaaccagt
    15541 caggaggagc agacctattt tcaaaatctg gcagacctgg tccagctaga agtggaagca
    15601 gaggtcagcc tgccagctgg tcagcggaat ttcaagggct ttgactatca ggcctatctg
    15661 aaaacacagg gcatctatcg gactgtcaag ctaacggcga ttaagaagat tgtccctgtc
    15721 cagtcttgga atgtttttga ctggctgtca acttggcgga ggcaggcctt ggtctatgtc
    15781 aaaaccaatt ttccggctcc catgagtcac tacatgacag ggcttttgtt tggggagctg
    15841 gatagtgatt ttgaccagat gagtgacctc tattccagtc taggaatcat tcatctcttt
    15901 gccctgtctg gtatgcaggt gggctttttc atcgacaagt ttcgttggat tttgttgcgt
    15961 ctgggcttga ccaaggaaac agtggataag ttacaaattc ccttttccct tgtctatgct
    16021 ggtttgacag gcttttctgt gtcggtggtg cggtccttgg tccaaaaaat tctgggtaat
    16081 ctaggcttgc ggaagttgga taattttgcg gtgacggtct ttatctgtct gttgatactg
    16141 ccccgatttt tactgacagc aggaggagtg ctgactttta cttatgcttt cttgctgacg
    16201 gtctttgatt ttgaggattt ggggcaggtc aaaaaggctg cggtggagag cctcagtatt
    16261 tcactgggaa ttttgccggt gcttatgacc tatttctatg cctttcagcc tctatctatc
    16321 ctcttgacct ttgtcttttc ctttgtcttt gatgtcctac tcttgccagg tttgtcagtc
    16381 atttttctcc tgtcgccagt tgtcaagatg acttgggtca acggattttt cgtctttatg
    16441 gagaaaatca ttgtctgggt ggctgatttg ggattgcggc cttggatact gggcaagccg
    16501 tctgagctgg tcctcttgct tttgctggtc agcctcttct tgctctacga tttccacagg
    16561 agaaagaaat ggcttctagg actgagcttg gtcctcgctc tgctattttt catcaccaaa
    16621 cacccgctgg aaaatgaggt gacggtgctg gacatcgggc agggggacag catctttttg
    16681 cgggatatgc gggggcggac ggttctgatt gatgtaggcg gacgagtcga tttcgcggcc
    16741 aaggaagcgt ggcaggagcg gtctcggcag gcaaatgcag agcggacttt gattccctat
    16801 ctgcatagtc ggggtgtgga taggattgat agtttagtcc tgacccacac cgacacagac
    16861 catgtggggg atgtgctgga agtggcgaag caggtccaga ttggtcggat tgtcgtgtcg
    16921 ccgggaagtc tgacggtgcc tgactttgta gcgaccttga aaaaaatcaa tgttcctgtc
    16981 catgtggtaa aagtgggcga ccgcctacca atttttgact cctatctgga ggtcctctat
    17041 ccagacggga caggcgacgg tggcaataat gactccattg tcctttacgg tcgcttgttg
    17101 gaaactaact ttctctttac aggagacctg gagcaagggg agttggactt gatagaaacc
    17161 tatcccaacc tgcctgtcga tgtcctcaaa gccggtcacc atggctccaa aggctcttct
    17221 tatcctgaat ttttagacca tatcggtgcc aagattgcct tggtatctgc tggagaaaac
    17281 aaccgctaca agcatcctca ccaagaaacc ttggaacgat ttgacagccg gaatatccaa
    17341 gtctatcgca cagaccagca aggagccatt cgcttccgag gttggaagga gtggaagatt
    17401 gagacggtga ggaggtaaaa tgataaatcc tatgcactta tggttctata gtttcaaagt
    17461 ttatgtgctc gctgccttat ctggctatat tctgcactat gttactacgc cagcttctgt
    17521 taacgacttc aaagaggttg ctgccttatt ggaaagatgc taacaatctg tgattgtagc
    17581 agatttgggc tatctcagtc agcagtcttg ctcattccat tgtatttcaa atagtctata
    17641 ttttgaattt aagaattgat tttcatttct tttcattaaa tattgaaatc gttttcgaat
    17701 ttgtggtata ataaagtatg atttaccaaa ggaggaagtc ctatgtctgt taaagatttt
    17761 atgacccgta aagttgttta tatttcacca gatacaaccg ttgcacacgc tgcagatatt
    17821 atgcgtgaac aggatttgca ccgtctacct gttattgaaa atgataagtt ggttggtttg
    17881 gtcactgagg gaacgatcgc agaagctagt ccatcgaagg caactagcct atctatttac
    17941 gagatgaact accttttgaa taagactaag gtcaaggatg tgatgattaa gaatgttatc
    18001 acagtctcag gttatgctag tcttgaagat gctgcttatc tcatgtataa aaacaaagtg
    18061 gggattcttc cagttgttga caacggtcaa ctatatgggg tcattactga tcgtgatatt
    18121 tttgcagctt ttcttcatgt ctcaggttat ggagaagaag gagtacgcgc tcggttcctt
    18181 gttgaaaata aggcagggga gttagaaaaa attattcgat tggtggcaga taaggattat
    18241 aatattgtat ctactgtgca acttgctacc aagtccggaa aagttgtcat cgaagtgcag
    18301 attgacggaa aagttgatgt tgaagaagtt cgaactcttt tcgaaggtgc aggtatccaa
    18361 gtggatagct tggttccgac tgttgctaaa aatatttaaa aaccgagatt tctcggtttt
    18421 tttctttagc tatcattcta gtattttagg ggaatgtgat ataataaagt atatcatgtg
    18481 tgaggaggct ctatggggca caaatataaa aagtataaga aatatggtaa aaataattca
    18541 ggacttgtgg ccctccttgt tttattggca atcggttttg tcatgagttt ctggtatatc
    18601 ttattgccca ctgggctctt aattggctat ttttacaaga gagaggctat ccagcgtttt
    18661 ttgaatagag attctataaa acgcttgcaa gtattagcgc tatctattcg ttcgggctat
    18721 gaaaagcatc aagagctctt ggtggaaaat ggtgaggata aggttgtatt acagttgaga
    18781 aacagactgt taggacaatt atttgaatta gatcagctct atcaaaaatt tggaaaatat
    18841 ctgaatggat atgaaagtaa agaagttgta gataccttgc aactaaaata tcatttaaaa
    18901 ctgccagaag ctaaaacaga aaaaaatact gacacacagg tttctactgg tggtaatgct
    18961 gtgatggatg aacaaggcat gatagcggat ttagctcctg aaattctaga aacctattgt
    19021 aatattcaaa gagacaatct tgttattctt gaaaagctgg aaaaggcgac agataagcgg
    19081 gaagaattga cagctatcca tgaggccaat atgaatcggt ttaacgatat tttacagggt
    19141 tatttgaaaa tcaaaaaatc accgaaagat tattttaacg cagaagaacg attggtgcag
    19201 gcaaaatcag ccatggaaat gtttgataag gatttggatg ataccatcaa acaatttaac
    19261 gaagcggata tgaaagattt tgaagtcagt ctgcgtatga tgaaaagaga agaggaatag
    19321 agaagatgtc aggatttaat ttcgatattg atcagattgc taataatagt ttatcaacca
    19381 aagataagac aacagagctt attcaagcga ctccgactgg agataattca aaagtgtctt
    19441 tcttggcaca gttgacaccg gaacaacaaa caggtattcg tgccaaggct ccccaattgg
    19501 tggataattt cttagctaat caaaatgtcc tcttggattt tggtaaggaa gcggtagaag
    19561 aagtcaatgc cacggtcaat cacattttgt cagaacagaa gaagattgaa attccacagg
    19621 tcgatgagct tttggccaat accaaccgtg aattgaatgg ttttgtggct aagtataagg
    19681 acatttccac aactgctgaa ttagaaaaga aacctggttt cttccaacac ctgttcaagc
    19741 agaccaaaaa tgatttgcag gaattttatt tcgattcgca gaccattgaa aagaaaatgg
    19801 atagcatggc agccagtgtg gtcaagcagg aagaggtgtt ggcgcgcaat attgtttctg
    19861 cagagctttt gattgaaaat aataccaagt ctatcgagaa tttggtgggg gtcatcgcct
    19921 ttattgaagc gactggtcaa gaggctgccc agcgagcaaa agcagagcaa gaacgcttgg
    19981 caggtctgca accaactacg gtagattatc aagtagcttc tgagaagttg gcacgtgtaa
    20041 cagaggttgc taatatcctc gaacaacaac attctgagta tatgagtcgc ttgtatgtcg
    20101 cgtggacaac gacaccgcag atgcgtaatc tggtcaaggt ttcttcggat atgaaacagc
    20161 gccttgggat gttacgtcgc aatactattc caacaatgaa attgtccatt gcacagttgg
    20221 gcatcttaca acaatctatc aagtctagcc agacggcaga tgcgattgtc aatgctaata
    20281 atgctgccct tcaaatgctt gcggatacat caaaagaagc catcccgatg atggaacgca
    20341 cagctcagaa tccgaccctt tcagtagcat ctgttaccaa attggcagaa agtttggttg
    20401 cccaaaataa tggcattatt gcagctatag atgaagggcg tcagaaacgt cgtgagttgg
    20461 aggcagctat tgtacggtca gcagagacta tcaacgattc tgttaagcta cgcgatcaaa
    20521 aaatcattgc tgctttgctg gagcaaggca aagaagcaca gtctgaggca gagcaaccac
    20581 ttgaaaccaa tcaataatat aaaacctgca gttcagcgaa actgcaggtt tgtttaatgg
    20641 cgttctattg gttttttatc tcgatctaaa gtaaatccct caccgagtac ttcatgtgcg
    20701 tctgtaatgg tgataaatgc gtgggggtca atacgatgaa taagctcctt catctcttgg
    20761 agttggctct tatatatgac cgagtaaatc atgttgacat cggctttgct gtagaaacct
    20821 tgtgctttga taaaggtgac accacgctcg atttcacaat caatagcctg agccaattgg
    20881 tcagattttt gagaaacaat cataacaccc ttgctaccat atccgccctc cgtgacaaaa
    20941 tcaataacct tggaagcaat agcaaccatc attaaagtat agagaactgt tcggaggtct
    21001 ttaaaaacaa taacaatcag agttaggatg aggatgtcaa ctgcaagaat gatttgtcca
    21061 atggagtaag gtaggaattt atgacctata cgagcaataa tatcgcttcc cccagtcgtt
    21121 ccgccagcac ggaagatggt tcctaatcct agtcccataa gaatcccacc caggatacta
    21181 acgagtatca aatcttgttg tagattgatt gaaaaatgga ttttttcaaa aatggccaac
    21241 caaaaggtaa cgctaaaggt tcctaagata ctgagataga gagtcttctt tccgagtatt
    21301 ttccacccga ggatgaacaa tggaatatta atcacaatgt tcattatcca aggttgaata
    21361 tgaaaaaggt agtaaataat cagcgtcaat ccagttgcgc caccctcgaa tagacgattg
    21421 ggcatgatta aataatttag cccaaaggca aatagccctg caccaagcaa aataagtaaa
    21481 atatttttca aacgaaccat aagcatctcc gaatatgtgt atatatcaat tttaaaagat
    21541 tttctcctta aaaacaagtc aattttcaag tgattttttg actaattttt ggtaaaatgg
    21601 aatgaatatc taagaaccag tcttcacaag tgaagtgctg aactgtgcat actggtacta
    21661 agagcgaggg aaagatgaga aacggttttt ttattacatt tgaaggtccg gatggggcag
    21721 ggaaaacaac ggtattgcaa cagttattgc cagccttgca ggaattgggg ccagaagtag
    21781 tcacaactag agagccaggt ggggtggcta ttgcagaaga aattcgtaat attattctga
    21841 atcctgcaaa tacagcgatg gatgataaga cggagctgtt attgtttatt gcagcacgac
    21901 gtcagcattt gaaagagaag attcttccac ccttggcaca ggggaagttg ctcttgattg
    21961 atcgttttat cgattcctct attgcctatc aaggatttgg acgggggttg gatataggtg
    22021 acattcattg gctcaaccag tttgcaacag atggtttaaa gccagattta actctctatt
    22081 ttgatattga tacagaagag gggctggctc gaattgcccg caatgctgac cgtgatgtgg
    22141 atcgcttgga tatggaaaaa gcagatatgc atagacgggt gcgtcaaggc tatcttagta
    22201 ttttagagca ggaaccagag cggtttgtaa agattgatgc cagccagcca ctagaggctg
    22261 ttgttgcaaa tgctctggcg gtcattaaga aacggtttgc agaaagaaca tgaagattga
    22321 agaacttaga aacttacaac cctatgtatt tcaacgtttt gtgacaattt tagagcagag
    22381 acgtttggca catgcctatt tattttcagg tgactttgct agttttgata tagcaatttt
    22441 tctcagtcaa tcgttatttt gtcaggagaa agaaggcatc cttccttgtc agaagtgtcg
    22501 gtcttgtcgt ctaattgaag caaatgagtt ttcagatctt actgttattg caccgcaggg
    22561 aaatgttatc aaaacagata cgatacgtga attagttaag aatttttcac aatctggatt
    22621 tgaatccaat aagcaggttt tcattattcg tgatgctgag aaaatgcatg ctaacgcagc
    22681 caactctttg ctaaaagtga ttgaagaacc tcagtcagcc attcacatct tcttattgac
    22741 caatcaggaa gaagctgtcc ttcctactat caagagtcgg acacagatta taggttttcc
    22801 taaaaatatt ccagctatgg agcgaatgtt agaagaggag ggcttgttaa aaacacaagc
    22861 gaatctctta gctcaactgg tttcaagtca agaagaagcg aaaaagttag cagaaaataa
    22921 aaacttttta gatttgatgg gacaggcaaa gaaatttaca gacttgctct tggtggagcc
    22981 tacacgtgct tatttgcaag ttggaatcct agtgtcttta gctgtggaaa aagctgagca
    23041 gggacgtttg tttgaccttc tgagtctgat attatctgag aaaatgatgg aatcggcaaa
    23101 cgtacgtgaa aaaatggatg ctgttcttaa ggctaagaag atgtggcagg caaacgtaag
    23161 tctacaaaat agtctagagt atataactct gtaaaataaa agaaagggag ataatggata
    23221 aaaaagaaat ttttgatgcc ctagatgatt tttcgcagaa tcttctaacc acgttggcag
    23281 aagtggatgc tatcaaaaag catttacagg gagttattga tgaaaatacg accctccgct
    23341 tggaaaattc caagttgcgc gaacgtttgg aaaaagaaga taagacaggc cataaatctt
    23401 ccaactttgg taaggagaat ttggagaata tttacgaaga tggtttccat atttgtacct
    23461 tctcttatgg tcaacgtagg gataatgatg aaccttgtat gttctgtgta gaattattga
    23521 atcgagatta ggatgaaagt acaaaaatca tttaagggac agacgagttt tgggacttta
    23581 tatctggtgc caacgcctat tggaaactta caggatatga catttcgagc tgttcagatt
    23641 ttgaaagaag tggatataat tgcagcggaa gatacgagaa atacaggcct cctactcaaa
    23701 cattttgaag tagaaaccaa gcaaatatcc tttcatgaac acaatgccca tgaaaaaatt
    23761 ccagttttga ttgattggct caaatctggt cagtccattg cgcaagtttc tgatgcaggc
    23821 ctgccttcca tttcggatcc tggtcatgac ctggtagggg cagcgattgc ggaggatatt
    23881 cctgttgtag cacttccagg agcatcggcg ggaattacag ccttgattgc atctggtttg
    23941 gcaccccagc cacatatttt ttatggattt ttaccgagaa aatcggggca gcaaaaagaa
    24001 ttttttcaag aaaaaaagac ctatcctgag acgcaaattt tctatgaatc tccatatcgt
    24061 gtggcagata ccttagaaaa tatgttgaca gtttatggtg atcgtcaggt aacggttgtt
    24121 cgagaattga ccaagttata cgaagaatac cagagaggga gcatttccga attactagag
    24181 tatttggaag aaaatccact taagggagaa tgcttgatta ttgtcgaggg tgctggtgaa
    24241 gaagtctatc cttctgctga tgaagtggac ttgaaggctg aggtagaaag ggaaattgca
    24301 agtggcataa aacctaatca ggctatcaaa gaagtggcca aacgctacca actcaaaaaa
    24361 caagaagtat acgatatata tcatggacta ggttaagacc tagttttttt gtatgtttat
    24421 gcaagcttat actcttcgga aatcaaaatt atccgttgtc aagagccttg atgagtgaaa
    24481 agctccagtg gatcttttca gcctgttacc ttgaaatgag aaagtaacag agttctatct
    24541 tcggcttaat gacgcgaaca cagttctcta tacttccagc cttcaactat atcccagcta
    24601 agctactttt gattttcatt gagtattaat atgcagatag caattggtga cactccccaa
    24661 acagtcaaat ctggtcataa aattttcatt gaaacctgat aaatccctgt gaggcaagcg
    24721 cctcgtttat ggctaaaagt aagaggtgct ttagaaagta gaataaatat aagaaatccg
    24781 aatattttta caaaataatc atatttcatg gaattgtctg aatatttgtg atataatgaa
    24841 cagactaact taatggaggg attttatgac aatctacaac ttctctgcag gtcctgcagt
    24901 attgccaaaa ccagtacttg aacgcgccca agctgaattc ttggactaca atggttcggg
    24961 aatgagcgtt ttggagatgt cgcatcgctc caaggacttc gatgatatta ttaaaggtgc
    25021 tgaggcaacg cttcgtgaat tgatggccat tccagataat tacaaggtta ttttcttgca
    25081 aggtggagct tctttggaat tcacaatgat tccccttaac ttcgctcaag gcaagaaagc
    25141 ctactatctt gtaggtggct catggggtaa aaaagcctat actgaggctg tgaagctgtc
    25201 taaaacaatt gcctttgaac caattttgct tggatcaacg gaagatatta cctatgcaga
    25261 attgccaacc ttcgataaaa atgatattga tccaactgct gcttacgtgc atttgacaac
    25321 aaataacact attgaaggaa cagcagttta tgatattcct gacaccaatg gtgtgccagt
    25381 cattgctgat atgtcttcaa acatcttagc ggctcgctat aatgttgaag attttgccat
    25441 gatttatgct ggtgctcaga aaaatattgg tcctgctggt gtgacggtgg tgattgttcg
    25501 tgaggacttc ctcaatgatc aaccaatgct ttcaagcatg ttggactacc gtattcaagc
    25561 agaaaatgac tctctttata atacgccacc agcttattct atctatattt ctaaactcgt
    25621 ctttgaatgg gtaaaagaaa ttggtggtgt tgatgagatg gagaaaatca accgtgaaaa
    25681 atctgggttg ctttatgact atatcgacca gtctaatttc tatacaaacc ctgttcgtaa
    25741 aaaagaagag cgttcagtag cgaacattcc ttttgtctca ccaagtgaag aattagatgc
    25801 taaatttgtc aaagaagcaa cagcagctgg ttttaaaaac atcaaaggtc accgttcagt
    25861 aggtgggatg cgggcgtcgc tctataatgc tttcccacgt caaggtgtgg ttgaattgat
    25921 tgaattcatg aaaaaatttg cagtggagaa tgcttaatgg aaattagatt agcacatcca
    25981 aatgagatgg aggctattgt caatattctt gaagatgctc gtgcatttct agcaacctcc
    26041 ggtatcaatc aatggcaggg agagtatcct aataaagaga atatttttga tgacattctt
    26101 tctggcagag gttacgttgg tctagttgac ggtaaggtgg cagcttatgc cgccgttcat
    26161 cgtggtcaag aagcagaata tgaggccata tatgaaggaa aatggcagca caatcatcct
    26221 gtatatacaa catttcatag aattgcagca gctgacgaat ttcgtggtca aggaatcata
    26281 caaacttttt tgcaaggttt aattgaaggt caaaaaggac cggatttccg ctgtgatacc
    26341 cacgagcaga ataagacaat acagcacatt ctaaaaaaat tgggctatgt ctattgtggt
    26401 aaagtcccaa tagatggaga acgtctagcc tatcaaaaaa tcaagcaaaa gagcgagcgg
    26461 agtctttacc aggaaatcag tgaagacgac cgttggttac tcggaaataa ttaatgaaat
    26521 aaagaaagaa aaggcggcag ctattccgcc tttttaggta aaaataaatg gtatttagcg
    26581 tacgtacttt taacaatatc aatcaaattg gtcttaagga attaggcaat aaattccaga
    26641 ttgacggaga tcatgcagca aatccagatg cctttattat tcgatctgaa aatttgcatg
    26701 gatttgattt tcctgaaaat ctaaaagcta ttgcccgtgc tggtgcaggg actaacaata
    26761 ttccaatcga agaggcaaca gagaaaggta ttgttgtctt taacactcca ggtgccaatg
    26821 ccaatgccgt aaaagaggca gtcattgctt ccatcctctt gtcagcacgt gactatatcg
    26881 gagcgactgc atgggcaaat acattgtcag gagatgatgt acctaagcag gttgaagcag
    26941 gtaaaaagca gtttgctggg acagaaattt caggtaagac tcttggtgtt atcggacttg
    27001 gtgctatcgg tgcgcgtatt gccaacgatg cccgccgttt gggaatgaat gttctcggtt
    27061 acgaccctta tgtatcagta gaaactgcat ggaccatttc aagccatgtc aaacgcgtgg
    27121 atgacttgaa agaaatcttt accaatgcgg actacattac tgttcatgtt cctttgacag
    27181 ataagacacg aggacttttc aatgcggata gcttttgtca aatgagaaaa ggaacaacct
    27241 tgataaactt tgcacgcggt gaattggtta ataatgctga tttgtttgaa gcaattgagg
    27301 caggagttat caagaactat atcacggatt ttgggacaga agaagtgctc aacaaggaca
    27361 acattatcgt cttcccgcac gttggtgggt caacagagga agcagagctc aactgtgcca
    27421 ttgctgcagg tcagaccatt cgtcgtttta tggagacggg tgaaattatc aactcagtta
    27481 acttcccaaa tgtgaaacaa ttcctagatg caccgtatcg tattaccttg attaataaga
    27541 atattcctaa tatggtggca acgatcacaa cggctgtatc tgagttggga atcaatatcg
    27601 ataatatcat caataagtct aaaggtgact atgcctatac tttacttgat ttggatgaag
    27661 cggataaagt gaaaattgag cagttggttg ctaaatttga agcaacggat gcaattgtca
    27721 aagtgcgtgt cattcagaat aaaaactaat catgctgtat aaacaagtct atcacagtcc
    27781 acttggcccc atgtcattaa ttgctagtga taagggatta agaggggcct ggtttgaggg
    27841 acaaaaatat tttgaacgag gcttgaatga gaaagctatt ttagcctccc atcccatttt
    27901 agaccagaca gctcgattgc ttgaccagta tttttcaggg gatcaggtgg acttttcaaa
    27961 ccttccatta gaagctgtgg gaacaaattt ccaagagcat gtctggcaat tattgaagat
    28021 tattccgatg ggtcagacga ctacctatgg acaactggct cagcaactgg gccttcgttc
    28081 tggtcaggca gtaggaggag cagttgggcg taatccttat tctattattg ttccttgtca
    28141 ccgagttctc aatcagaaag gacagttgac aggttatgca ggtggactgg ataagaaaat
    28201 ctggctcttg cgacatgaga atccagaatt tgaggtgaaa gatgatttta ttttatgagt
    28261 atccaaaatg ttcgacttgc cgagcagcaa aggcggagct gaagagtttg ggattggaat
    28321 ttgaagctat tgacattaag tcaacaccgc ctagtgctga agagataaaa gcttggatgg
    28381 aggcgacggg actagaattg aaaaagtatt ttaatacttc tgggaatagc tatcgtgaat
    28441 taggcttgaa agataagttt gatagtctta gcttggagca ggcacttaat cttctagcta
    28501 atgatggtat gctgattaag cgtcccctac tgattcagga tggtaaaatc ttacagattg
    28561 gctatcgaac aaaatacgaa aatctcggtt tataagccga gattttgttt attatagtgc
    28621 atattctatt gaaatatatt catgatgttt tttcaaaaga tagagcatct gaggcttatc
    28681 ttctaagagt ttttggataa tttcgtgatg gacattgtgg agattgattt taacgcgaat
    28741 cttcatgcct tgtttgaaaa tatggatttc gacatcattg ctatcttcct ttaagtaagg
    28801 ctccaatagc tgatagatag aatcatgtat ctcagggaaa tggatcgttc cgttggcgag
    28861 ttccttgaaa gatgccacta ataagttcca aggttcctta aatgaaatga ttgctagtgc
    28921 tagtgtcaaa aagaagtcgc cagtataatg caggaagccg aaccaagagt tgataggaac
    28981 aagatagagc agaagaattg caattccaat tgcacctgaa atgagtccgt ctacaaggtt
    29041 gccttttgct tctgctaata tgatagtaga cagatgattg actttggcac tcatatggcg
    29101 gttgtatagg taaagcccca tacagacaaa aaacatggtt atggtataag ggagaacggg
    29161 acctgtagtc atttgatgac cgattccatg aacaaagtaa gcaaaggctg tcgcgcttgt
    29221 ttcaagtaca gcaaatacaa ggagtagtag agttgcgaga gatttcatga tagcgtagag
    29281 aggttctaga aagtatagtc cttgaggaaa agtctcggtt ttccgatggc tatttttcga
    29341 tatgtaaact gcaactaagg acgaaataaa tgctattaga gaaaagactc cgtctaggag
    29401 gagggcgttt aggtcagtca tgatataaac ggcaatacct gctagtccag ataaaccgtt
    29461 cacaacagag gaaacagtta gagatttgcg ttcgataatt ttgtggtcca taatccctcc
    29521 ttttaatata tatctatata tttattttac cacaaaatga caccgttttc aaattgagcg
    29581 gattaaaaca aggtagagtg ataagaaata aaggctcaaa acccttgcaa tagatctacg
    29641 ggttttaagc ctttaatatc tgttatctga taattgaaat caggttaatt tccactgtta
    29701 gaatgaaatc tccatcacaa ttggtgtatg gtcctgacga gcaccggagt caatcatatc
    29761 tgacttactt actttgtcgg cgatgcggtc gctgacaagc cagtaatcaa ttctccagcc
    29821 tgtattgttg attttactgg tgcggctacg ttgtgcccac caagtatagg cgttgagaac
    29881 atcaccgtgc aagtggcgga aggtatcagt aaaaccttta gctagaagat ttgtaaaacc
    29941 ttgacgttct tcatctgtaa atcctggaga ttgacggtta cttgcgggat tagcaaggtc
    30001 aatttccttg tgagcaacgt tgtagtcacc tgttgcaaga acaggtttgt ggctatcaag
    30061 ttttgctaag tagtcagcat actgtacatc ccagatttga cggtcagcaa gccgtttcaa
    30121 gccatcacca gcatttggcg tataaacttg tgtgacatag aagtcatcaa attctagcgt
    30181 gatgatacgc ccttcagaat ccatggttgt tggagcacca atctcaggaa aggttatggt
    30241 tggagttaga tggtttttgt agaggaagag tgtaccagca tagcctttgc gagctggttc
    30301 tacagatgaa cgccaggtat tggcatatcc agggaagtag ctttccaaaa tttctagatg
    30361 ctttttagtc ggtcccttat ctgacaattt tgtctcttga atggcgataa tatcagcgtc
    30421 ttctgtcaca agtgtatcga tgactgcgcg tgataatagg gcgcgaggag actctgcagt
    30481 caatgcagcg ttaagagaat caatgttcca agaaatgagt ttcataattt tccttttcta
    30541 gtctgttact gttttacatt ataccaaaaa taaaagttgc aggcgaatat ggaaacttga
    30601 aaaaaatttt ataatt
//
LOCUS       DBNFCO010000016        30504 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.016, whole genome shotgun sequence.
ACCESSION   DBNFCO010000016 DBNFCO010000000
VERSION     DBNFCO010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 30504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30504
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.016"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            <1..239
                     /locus_tag="AC1PIV_000631"
     CDS             <1..239
                     /locus_tag="AC1PIV_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HIP6611678.1"
                     /translation="NRLKKHMFWIGLISLVLMLVDNVLFCYFNIECSRTLNQIEQTIC
                     IILSILVFLGVLNNKPDVKVEDIMKNGMSSKNQK"
     gene            590..1345
                     /gene="ldcB"
                     /locus_tag="AC1PIV_000632"
     CDS             590..1345
                     /gene="ldcB"
                     /locus_tag="AC1PIV_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase LdcB/DacB"
                     /protein_id="HIP6611679.1"
                     /translation="MIMKRTILLCLPTILLLAACHQNINQANTTKNSSTVVSTTSSQS
                     ASTTSEQSTSSSTSAETNQEVTSTETQVNFNGSYYSVQGKYGEVIIVNKKHPLAADYA
                     PGENPEALAAFQRLIADMQALGFGISNNYSGFRSYETQSSLYQSYVNQEGQAAADRYS
                     ARAGYSEHQTGLAFDLLDTSGNLLEEPNASQWLATNAHLYGFVVRYLPGKESSTGYMA
                     ESWHVRYIGQEATDIYNSGLTLEEYFGVPGGDY"
     gene            1434..1877
                     /locus_tag="AC1PIV_000633"
     CDS             1434..1877
                     /locus_tag="AC1PIV_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HIP6611680.1"
                     /translation="MLKAMEVYLVTNGNGLEAIEFYKNALGATVEQVNLFKDFLPDCP
                     AELENYVMNAQFRLNGQRFMLSDNNPEMPYTVGDNITVALITDDAETAQELYSKLSVD
                     ATAINMELQAVPWSPAYGNVTDKFGISWQINAEVEGYGQEYYAEN"
     gene            complement(1905..3515)
                     /locus_tag="AC1PIV_000634"
     CDS             complement(1905..3515)
                     /locus_tag="AC1PIV_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HIP6611681.1"
                     /translation="MSKSIIWELVKINILYSNPQLLASVKKKQSKRKDASFSAYKSVL
                     LQQVFMVLSFGLLYSVFFMGVDYSQSIGFFSLQLALFTIIAIVYGFTGFFSVFYDSKD
                     TKLYLALPLKPQEVFLAKILSAQGMVLPFLMPCLSLLLITYWQIGGPLLALASIPSFL
                     ILWILVNLVNLIIMHFVGEVLTKSPRKTLISTILMTGSSLLAFAALMFLQSQQTVSLE
                     SGGFVDFPIIPIFAGFHYLVSHTISLETLLHFGLPFILMFGLITFAFKTVIPNYFNQV
                     LAIENASTKRTNNAKSAKIPSNLNQALVKHHLSTLKDSNLMVQTMIQPIIMGVALFPS
                     FSRFTENGGLSSVEWDFFGIALLAGFLLGSLFAGSTTFIGVAMSLEKENYHFIRTLPI
                     SFKKFIIQKFWVLAAVQFALPTLLYFALALGFMKVKLILAVFFTVGIIISALLTGQIY
                     YWRDQRLLMLNWQNSNQLFGRGAGQWLIAGSIIGTMFLGAIILVVSIILAGTIGAAYV
                     SSALMTLLFVLSAALQLYIYKAYWQKLK"
     gene            complement(3512..4255)
                     /locus_tag="AC1PIV_000635"
     CDS             complement(3512..4255)
                     /locus_tag="AC1PIV_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIP6611682.1"
                     /translation="MIQFDHITKTYGETIALDDLNLTIESGEIFGLIGHNGAGKTTTI
                     SLLTSIIEASYGTISVDGLNLEENRDEVKKRIAYVPDSPDIFLHLTAFEYWHFMGKVY
                     GVEKDTVDDRIAKLSSLFDMTARQHEPIDSFSHGMRQKTIIIGALIPNPDIWILDEPL
                     TGLDPQASFDLKQMMKEHAQSGHTVLFSTHVLSVAEQLCDRIAILRKGQLIFVGSLDE
                     LKSQYPDKDLETIYLELAGRQQVKAGEEV"
     gene            4495..6279
                     /gene="uvrC"
                     /locus_tag="AC1PIV_000636"
     CDS             4495..6279
                     /gene="uvrC"
                     /locus_tag="AC1PIV_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HIP6611683.1"
                     /translation="MNDLIKHKLELLPDSPGCYLHKNKYGKIIYVGKAKNLRNRVRSY
                     FRGAHDTKTEALVAEIADFEFIVTDSNIEALLLEINLIQENKPRYNIMLKDDKSYPFI
                     KITKERHPRLLITRQIKKDGGQYFGPYPDVGAANQTLKLLERLYPFRKCKLPENKYCL
                     YYHLGQCLAHGDNMPSLSDYDKMAKEVAQFLTGHDDKIIKEVQDKMKAAAGNLEFEKA
                     AEYRDVLQSISTLRTKQRVMAHDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERNVNL
                     FPYYNDAGEDFLTYIGQFYRDQQHLIPSEVLIPQDIDQEAVEALVDTKVIKPQRGEKK
                     QLINLATKNARVSLEQKFNLLEKNLEKTYGAVENIGQLLGIPTPVRIEAFDNSNIMGT
                     SPVSAMVVFENGVPNKKEYRKYKINTVEGPDDYASMREVLQRRYSRVLRDGLTPPDLI
                     IIDGGQGQVNVAKQVIEQELGMSIPIAGLQKNDKHQTHELLFGNPLEVVELPRNSQEF
                     FLLHRIQDEVHRFAIEFHRQVRSKNSFSSKLDGIEGLGPKRKQTLMKHFKSIGNIQSA
                     SLQEIAEAGVPYKVAEKVKESLSSKDEI"
     gene            6336..6464
                     /locus_tag="AC1PIV_000637"
     CDS             6336..6464
                     /locus_tag="AC1PIV_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HIP6611684.1"
                     /translation="MAFGEEKHKKTTFEKVTLVIVVVMVVATLAGLILPAINALMN"
     gene            6668..7981
                     /gene="obgE"
                     /locus_tag="AC1PIV_000638"
     CDS             6668..7981
                     /gene="obgE"
                     /locus_tag="AC1PIV_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HIP6611685.1"
                     /translation="MSMFLDTAKIKVKAGKGGDGMVAFRREKYVPNGGPWGGDGGHGG
                     NVVFVVDEGLRTLMDFRYNRRFKADDGEKGMTKGMHGRGAEDLIVRVPQGTTVRDADT
                     GKIITDLVENGQEFVIAHGGRGGRGNIRFATPKNPAPEISENGEPGEERNLELELKVL
                     ADVGLVGFPSVGKSTLLSVITAAKPKIGAYHFTTIVPNLGMVRTKSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHVLDMSASEGRDPYEDYVAINNELETYNLRLME
                     RPQIIVANKMDMPEAEEHLEEFKKKLATNYDEFEELPQIFPISGIAHQGLENLLEATA
                     ELLEKTPEFLLYDESDFQEEEAYYGFNPDEPEFAISRADDASWILSGDKLEKLFTMTN
                     FDRDESVMKFARQLRGMGVDEALRARGAKDGDIVRIGKFEFEFVD"
     gene            8355..8519
                     /locus_tag="AC1PIV_000639"
     CDS             8355..8519
                     /locus_tag="AC1PIV_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611686.1"
                     /translation="MGDKPISFKDKYGNFVSAADVWNAEKLEELFNRLNPNRKLRLER
                     ERLAREQEKE"
     gene            8883..12653
                     /locus_tag="AC1PIV_000640"
     CDS             8883..12653
                     /locus_tag="AC1PIV_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HIP6611687.1"
                     /translation="MRRSNKKSFDWYGTKQQFSIRKYHFGAASVLLGVSLVLGAGAQV
                     VKADETVASSEPTIASSVAPASTEAVAEEAEKTNAENTSAVATTSTEVEKAKAVLEQV
                     TSESPLLAGLGQKELAKTEDATLAKAIEDAQTKLAAAKAILADSEATVEQVEAQVAAV
                     KVANEALGNELQKYTVDGLLTAALDTVAPDTTASTLKVGDGEGTLLDSTTTATPSMAE
                     PNGAAIAPHTLRTQDGIKATSEPNWYTFESYDLYSYNKNMASSTYKGAEVDAYIRYSL
                     DNDSSTTAVLAELVSRTTGDVLEKYTIEPGESVTFSHPTKVNANNSNITVTYDTSLAS
                     ANTPGALKFSANDDVYSTIIVPAYQINTTRYVTESGKVLATYGLQTIAGQVVTPSSVR
                     VFTGYDYVATTTKAVQGPYPKGTVYLAGTVQKDTVQYKVIREIVENDQAVLKFYYLDP
                     TYKGEVDWRGTDTTGFIELLTTSPTTYKVGTIYDYNINSKITAPFTIDPTKNVMVFKE
                     SEQNEQGSKYRVIAQWSGDETTKGIYGKIYIATQVWTTKLGTNEWGWFDYSDDQAGIK
                     FNNKGFWPAGVQNTLRNATPATAVETTYIYKESSKYGDVIVEYYDTDGKQIVNSVVDT
                     PKSALGTEYNTDVDRRPASLVAADGTVYFYKEVKSDSAKTTGTVVAGTTTVKYVYEKA
                     GSVNVNFVDINGKVIKAPVSDEKDAKPGYNYDTDLDQKLASITFEGKEYKLVPAGDYP
                     VGKVGKGNNLIEVGNNTAKGIDPTTGKIEAGVNKEVTYVYRAVTGSVVVNYKDTEGNV
                     IKDPETDVSDAPVGDAYTTTDKKPNEIITKDGSRYVLVPSKTDGEENGKVIEGTITVT
                     YVYQKVANWIPEIPNVPETDRPKVPYPFDPTEPDEPIDPTTPGTNGEVPNIPYVPGYT
                     PVDPKDNTPLKPIDPNDPGKGYVPPTPENPGVDTPIPYVPVKKVVTNHVDEEGNPIAP
                     QEEGTKPNKSIPGYEFTGKTVTDEDGNTTHIYKKTPEVKNGTVVVNYVTEDGTVIKEP
                     VTDTPTSPEGTPYDTTDNKPKTITFKGEEYELVRVDGTENGKVVEGETVVTYVYRKVE
                     TPAKKVVTNHVDEEGNPVAPQEEGTKPNKSIPGYEFTGKTVTDEDGNTTHIYKKTPAK
                     KVVTNHVDEEGNPIAPQEDGTTPKRQISGYEYVRTVVDEEGNTTHIYRKLSNKPTTPE
                     KETPAKPQAGKTASGKAQLPNTGEASSVAGALGTAMLVATLAFARKRRRNED"
     gene            12944..16210
                     /gene="rexB"
                     /locus_tag="AC1PIV_000641"
     CDS             12944..16210
                     /gene="rexB"
                     /locus_tag="AC1PIV_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HIP6611688.1"
                     /translation="MKLVYTDIRNPLTQYLTEQTATFAEQGKRVFYIAPNSLSFEMER
                     KVLEYLPEQATFDIIVTRFGQLARYLMIDRKEAGQPLDDVGLAMIFFRVLSQFEDGDL
                     KVYGRLQTDFGFINQLVALYKELQRANMSILDLEAMESPDKQADLVKIFLAVTDILSK
                     EGFEHQSKLAQLTGLVETGQLDEQLKNIVLVVDGFSRFSAEEEALVSALNERVSEILI
                     GVYASKKAVQATYAEGNVYQANVDFLRQLSAQFQTKATYIGQEPVLDSIGKFSKNMEA
                     YYDYSGTMIDLTPADQEKIQLWEVVNQKEEVEQVATAIRQHVHQGARYKDILLLLGDV
                     DSYKLQIGKIFDKYDIPYYFGKAEEMSHHPLVHFVESLERLRRYRFRAEDLLNLLKSG
                     LYASISQKELDLFESYILFADMKGQAAFSRAFSVNGRADYDAEVIKEKRLVYDLTVLE
                     PLRAKIMEPLNQLFKAGPQSGTALLEKFMAFLEAIDLPKNMEKMSRNLSEVEQEKEEQ
                     VWKSFTHLLENFHQIFGKEKLKMDDFLAILQAGMQASHYRTVPATVDVVNVKSYDLIE
                     PHTAKYVYAIGMGQSNFPKVAKNTSLLTEEEMEKVNLVSASSSRFDLVSRENIKKNHA
                     AMMSLLNSATEQLVISTPQIYNEGEDSLSPYIKILQKMGLKSEERGRIKTLSPQDIGH
                     YKSLLSRLIESERPSLETEEWEGQRAFWTVLVRHLKKKLESQSIEIPTITGDIASKQL
                     SDETLAALYPEDKPLNLSASSLTNFYNNQYLYFVRNVLRLREQESIHPTAFQHGLFLH
                     RIFERVVMDQSELDFDQKVDKAILRTRDEAEFAMFYNQDADARYTEEVLDKIARSSAT
                     ILRDNDLVEIDGQEKSFRQDKALVFDLQNGKSVHVNGTIDRLDTLQINQAVGVVDYKS
                     SDQSFSVGDFYNGLKPQLVTYLAALQELDETKDKPVFGAMYLHLQDPIIKLKDTKNLE
                     QLEGAANTSLVYKGLFLKEESLGLNHFYQTRNQLYTEDEFAVLLNHNQELYKQAAMDI
                     LAGRFAINPYTKDGRSVAGEQLKAITGFEADRHMGMARRLVKEAKRQDWMERMKGGQD
                     "
     gene            16210..19860
                     /gene="addA"
                     /locus_tag="AC1PIV_000642"
     CDS             16210..19860
                     /gene="addA"
                     /locus_tag="AC1PIV_000642"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HIP6611689.1"
                     /translation="MAFEQFLSAEEIKAVQLAEAHSDKQQKRTAEQIEAIYTHGQNVL
                     VSASAGSGKTFVMVQRILDKLKRGIGIDQLFISTFTVKAAGELKERIEKKLNETIAET
                     TDMELRRHLSAQLADLTKADIGTMDSFTQKLVTTYGYSLGISPQFRILQDETEKASLK
                     KEVFDQLFADYLEEDENGAFRKLVRNFSGNRKDNSGFRQVVYQVHDFSQSTSSPTKWL
                     KEQAVQADLYSQERIEQMLEQGFKEKVLDKLYQAADFFRYHVEWGRNDFGSAKYFANV
                     EEVLDLLTGLDSLDQKDLMERVERILLINNQSRGKGLTNANRPKDEHLIAFKEEYNAG
                     KSQIISELRDLGQEVYELTLLKDYQVQALPLLILLRDFVLDFSQAYLDVKIKEAAFEF
                     GDIGHFAIRILEENADIRQFFQEKYHEVMVDEYQDNNHSQERMLDLLSNGHNRFMVGD
                     IKQSIYRFRQADPMIFQEKFELYQANPQSGKLILLKENFRSQIEVLEATNAIFTRLMD
                     RQVGEIKYDDTHSLVAGSPGQKIAQPKNEMEYLIYDQQDSANSSTDAEEETPLTAGEI
                     EVVAKEIIRLHNEEGADFKDITLLVQKRTHNDLIMSIFEKHGIPIVADGGAASYLQSL
                     EVMIMLDTLRVINNPLNDYALVALLKSPMFRFDEDELTRISLQAGTGFFYQKMEIAQQ
                     ASGQHPELMSEKLKKKITDFLSILENWRAYAKLHSIYDMIWKMFNEKFYYDYVGALPN
                     GSKRQANLYALGLRANQFEKTGYKGLSRFIAMIDRALANDKDLADVQEFLPQNAVQLM
                     TIHKSKGLEFKYVFLMNIDKRFNLEDHYQSVIISRKNGLGIQYLADMKDKVNSPLPQV
                     RVLMNTLPYQNNLQELKIANLSEQMRLLYVALTRAEKKLYLVGKGNADKLAEKYDGKK
                     ENGVLAQSTRESMATFQDWILAIDEAFSGEDLHFKKVFVTDEDLTEEKIGKLTLKSKL
                     EDASLKDIRQSEDIAQALDQLSSVQELNERYKAAIELPSLRTPSQIKKLYEPILEQEG
                     MEVMEKYQPKRTFNLPDFSKKPKITGAQVGSAVHELMQRLDLSWLVTEDTVRAALEAV
                     HAEQAIKDKINVQMILDFFDTDLGREILANTDKLHREAPFASLQTDSVSQENFVLRGI
                     IDGYLLYDDHIVLFDYKTDKYDQPIQLSQRYQAQMQLYAEALKKAYKIDRVDCHLILL
                     GGERIEVVEVNI"
     gene            complement(19982..20626)
                     /gene="plsY"
                     /locus_tag="AC1PIV_000643"
     CDS             complement(19982..20626)
                     /gene="plsY"
                     /locus_tag="AC1PIV_000643"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HIP6611690.1"
                     /translation="MLVNLILLFIAYLLGSIPSGLWIGQTFFNINIREHGSGNTGTTN
                     TFRILGPKAGTIVFVIDFLKGTLAALLPLIFHAQGISPIVFGLMAVLGHTFPIFAQFK
                     GGKAVATSAGMLLGVAPAFCLYLVLIFASSLYLTSMVSFSSVLAAALAILGALLFPAI
                     GIILPSYDWLFTVIIVFLGSFVIIRHKENIQRILKKEENLVPFGLNLTKQKKRV"
     gene            20769..22712
                     /gene="parE"
                     /locus_tag="AC1PIV_000644"
     CDS             20769..22712
                     /gene="parE"
                     /locus_tag="AC1PIV_000644"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HIP6611691.1"
                     /translation="MAKKEIDINNYNDDAIQVLEGLDAVRKRPGMYIGSTDGNGLHHM
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLSVSDRGRGMPVGMHATGKPTVEVIFTVL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFEQGGKPVTTLE
                     KIGTAPKSKTGTKVTFMPDDTIFSTTDFKFNTIAERLKESAFLLKQVTMTLTDERTGE
                     QEEYHYENGVQDFVSYLNEDKETLTPVLYFEGEDAGFQVQVAMQYNDGYSDNILSFVN
                     NVRTKDGGTHETGLKLAITKAMNDYARKTNLLKEKDKNLEGSDYREGLSAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVSDKLTFFLLENGELASNLVRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVINTAKAKMADILKNEEINTMIYTIGAGVGSDFTIEDVNYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGRVYIALPPLYKMSKGKGKAEKIAYAWSDGELED
                     LRKDFGKGFILQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVSVLMGD
                     KVEPRRKWIEDNVKFTLEESTVF"
     gene            22742..23554
                     /locus_tag="AC1PIV_000645"
     CDS             22742..23554
                     /locus_tag="AC1PIV_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATPase"
                     /protein_id="HIP6611692.1"
                     /translation="MKLQIWNESYSLQWKGTYFLALSDYPNIQDWELEKIVAFLAYEK
                     LYGRETLIDCEDKVMLEQLVYLSCCSPTAFPFTPSKKIVASTYDVGGNYVYSDFLSHT
                     CTVETAQEIFMSGQLLSAVRAFNKTHQELVQDNRNAAGDPEDYFDYVMLGWSNTSSGY
                     RLAMERLLGREPTEEELGNSFIPGVSFHFKYDDIVNADGYVFDGYHPAKVRDCLSLKY
                     LFACIVPSSEKSHFETIIPLDMSSKVYYLDYGQDGMADWSQKVYQFVENIAN"
     gene            23607..23711
                     /locus_tag="AC1PIV_000646"
                     /pseudo
     CDS             23607..23711
                     /locus_tag="AC1PIV_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935482.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
     gene            23735..24341
                     /gene="fic"
                     /locus_tag="AC1PIV_000647"
                     /pseudo
     CDS             23735..24341
                     /gene="fic"
                     /locus_tag="AC1PIV_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395946.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_function: GO:0070733 - AMPylase activity [Evidence
                     IEA];
                     GO_process: GO:0018117 - protein adenylylation [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="protein adenylyltransferase Fic"
     gene            24374..24877
                     /locus_tag="AC1PIV_000648"
     CDS             24374..24877
                     /locus_tag="AC1PIV_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YkvA family protein"
                     /protein_id="HIP6611693.1"
                     /translation="MPLRVKLTDRFQKRLSEWARKRKPFKNKQELEEKFGQALKIWQS
                     SKTRQHAENLLSEQGKLEHFLHSTERKLSRMPFGGDKFAAIPGLISMVRSYIRRDYSK
                     LPKATILAIIGALIYFFSPIDALPDFILGAGLLDDAFVLNACLKLIKTDVDDFRSWQA
                     SQWKAEE"
     gene            24880..25332
                     /locus_tag="AC1PIV_000649"
     CDS             24880..25332
                     /locus_tag="AC1PIV_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611694.1"
                     /translation="MIKFLRKKPTIEQLKKVPYASQYTEVLRSIWRADVPKYGISSTL
                     QGELLRQLEKLRWEAQANGNVNWCEEHSNYCRFIKETLYKGKLLSSQQKQELVLIMDY
                     LKSCGEYAQAYQENLIDDEELEIEKLAYVDDNLYDRVGDMIAFFYQRT"
     gene            25533..27986
                     /gene="parC"
                     /locus_tag="AC1PIV_000650"
     CDS             25533..27986
                     /gene="parC"
                     /locus_tag="AC1PIV_000650"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HIP6611695.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQERALPDIRDGLKPVQRRI
                     LYSMNKDGNTFDKGYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQDWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEMAGYLLADIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGATGISAGYATDIPPHNLAEVIDAVVYMIDHPTAKLEKLMEFLPGPDFPTGAI
                     IQGADEIKKAYETGKGRVVVRSRCEIEQLKAGKKQIVITEIPYEVNKAVLVKKIDDVR
                     VNNKVPGIAEVRDESDRTGLRIAIELKKDSDEQTILNYLYKYTDLQINYNFNMVAIDN
                     FTPRQVGLQKILSSYIAHRREIIIARSKFDKEKAEKRLHIVEGLIRVVSILDEVIALI
                     RASENKADAKENLKISYEFSEEQAEAIVTLQLYRLTNTDIVTLENEEAALREQIQTLA
                     AIIGDERTMFNLMKKELREVKKQFGNPRLSELQDQAETIEIDTASLIVEEETFVSVTK
                     AGYIKRTSPRSFNASTLEEMGKRDDDQLIFLQNAKTTQHLLLFTNLGNVIYRPVHELT
                     DIRWKDIGEHLSQTLMNFDTNEEIIFAELVENFEEGTYFAVTKYGQIKRVERKEFTPW
                     RTYKSKSTKYAKLKDAEDVVITVSPVVLDDIMLMTEKGYALRFNIEEVPIIGAKAAGV
                     KAVNLKDEDVVAAAFISNTNSVYLLTQRGSLKRMATEEIPVTSRAKRGLQVLRELKAK
                     PHRVFAAGPVLTDQGDFDLFSTANEDDTTSQILHVQSKTGKLYEVDVTQLSLSERTSN
                     GSFISDTISDEEVFRAWID"
     gene            28049..28666
                     /locus_tag="AC1PIV_000651"
     CDS             28049..28666
                     /locus_tag="AC1PIV_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4230 domain-containing protein"
                     /protein_id="HIP6611696.1"
                     /translation="MKIIKLFFSIKVYLWLVLSFLLLLCGVWGYGYISGEKSNQQEVS
                     VHAAIESVEQVNELVFLNTAVQKIVTAKNYTVLFGQEMPFSEKSALLIIKYKAKFGIK
                     SPVSIEHLSENRYKITLPAFEVIGLELDAEEPYTLYDKSGEILSFATEEIDTAQLITD
                     EFQSVEQEKFLADYQEDIKESAKNYYQNLFSAISPEIQLEFVFKE"
     gene            28777..29799
                     /locus_tag="AC1PIV_000652"
     CDS             28777..29799
                     /locus_tag="AC1PIV_000652"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HIP6611697.1"
                     /translation="MTVNIDWENLGFSYMKLPYRFIAHFKNSQWSEGQLTEDAELHIS
                     ESSPALHYGQQAFEGLKAYRTKDGKLQLFRPDQNAERLQRTADRLLMEPVPTDLFIKA
                     CKEVVKANADYVPPYGTGGTLYLRPLLIGVGDIIGVKPAEEYIFTVFAMPVGNYFKGG
                     LAPTNFLIQDKYDRAAPNGTGAAKVGGNYAASLLPGQYAKKQGFSDVIYLDPATHTKI
                     EEVGSANFFGITADNEFVTPISPSILPSITKYSLLYLAEHRLGMKAVEREVLVEELDQ
                     FVEAGACGTAAVISPIGGIQIADKLHVFHSETEVGPVTRKLYEELTGIQFGDIEAPEG
                     WIVEVD"
     gene            29866..30099
                     /locus_tag="AC1PIV_000653"
     CDS             29866..30099
                     /locus_tag="AC1PIV_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HIP6611698.1"
                     /translation="MSKKDKKIEIQIEDSKVLVNREEFPGYRLVIGKKVIGEIAELAE
                     NNFAVIKNGNTESFYKKLEKAVGNIIENYNLSH"
     gene            30151..30231
                     /locus_tag="AC1PIV_000654"
     tRNA            30151..30231
                     /locus_tag="AC1PIV_000654"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:30185..30187,aa:Tyr,seq:gta)
BASE COUNT         9344 a         5851 c         6976 g         8333 t
ORIGIN      
        1 agaatcgttt aaaaaaacat atgttttgga ttggactcat ttcgttggta ttgatgctcg
       61 ttgataatgt cctattttgt tattttaata ttgaatgtag tcgtacctta aaccaaatcg
      121 agcagacgat ttgtatcatc cttagcattc ttgtattttt aggagtgcta aataataaac
      181 cggatgtgaa ggtagaagac atcatgaaaa acggtatgtc atctaaaaat caaaaataat
      241 gtttgtttag aaactactga tgaggtatct agttgtactt acagttcagt atctctagct
      301 aagatggatt tttcaaaata tagtcagtat ctcctaaaaa actattttgt atataaatca
      361 ctttacttgt gaatacgact atttaacatc atatatgtcc accagtcgaa aggctggtgt
      421 ttctatttat gacatgtatg ttatcaggaa tgccactatt tgaaaggaaa agaatcgaga
      481 gaaattcaat gaatactaaa aatatcaata gtagttaaaa tcataagccg tcattagacg
      541 gggtcttatg attgtgctac aatagacata attataagag aacggggtga tgataatgaa
      601 acgtactatt ctattatgct tgccgacaat actgttacta gcagcatgtc atcaaaatat
      661 aaatcaggcc aatactacaa aaaattcgtc aacagttgtt tcgactactt caagtcagtc
      721 tgcttcaaca acttcggagc agtcaacaag cagctctaca tcggcggaaa cgaatcaaga
      781 agtaacaagt acagagactc aggtaaattt taacggttcc tattatagtg tacaaggaaa
      841 atatggcgaa gtgattattg taaataaaaa gcatccgctt gcagctgatt atgcaccggg
      901 cgaaaatcct gaagccttag cagcttttca acgattaata gcagatatgc aggcgctagg
      961 atttggtatc tccaataact atagtggatt tcgttcctat gaaactcagt caagtctcta
     1021 ccagtcttat gtaaatcagg aaggacaagc agcggcagat aggtattctg caagagctgg
     1081 atatagtgaa catcagacag gattagcctt tgatttattg gatacaagtg gtaatttatt
     1141 agaagagcct aatgcttctc agtggttggc tacgaatgca catctatatg gctttgttgt
     1201 ccgctatctt ccaggaaaag agtctagcac aggctatatg gcagaatcct ggcatgtgcg
     1261 atatattggt caagaagcga cagatattta caattcaggc ttgaccttgg aagaatattt
     1321 tggtgtacca ggtggagact actaatttta catttagtca gaaataagtc gaaaaatttg
     1381 tccgtataac taactcgtga tataataaac catcataatt ttggaggtcc atcatgctta
     1441 aagcaatgga agtatacttg gttactaatg gtaatggttt ggaagccatc gagttttata
     1501 aaaatgctct tggggcaaca gtggagcaag taaatctatt taaagatttc ttaccagact
     1561 gccctgctga actagaaaat tacgtaatga atgcacagtt tcgtttgaat ggtcagcgtt
     1621 ttatgttgtc agacaacaac ccagaaatgc cttatacagt aggtgacaat attacagttg
     1681 cgcttatcac agacgatgct gagacagcgc aggaactata cagcaagtta tccgtagatg
     1741 caactgctat caatatggaa cttcaagcag ttccttggtc tcctgcctat ggtaatgtaa
     1801 cagacaagtt tggtatctct tggcaaatca atgctgaagt agaaggctac ggtcaggaat
     1861 attacgcaga aaactaaaat agattggaca aggccttgtc caatctattt tagtttttgc
     1921 caataagctt tgtagatata aagttgaaga gcagcagata gaacaaatag taaggtcatc
     1981 aaggctgagc ttacataagc tgcaccaata gtgccagcta atatgatgct gacaactaga
     2041 ataatggctc cgagaaacat tgttcctatg atcgatccag caatcaacca ttgacccgct
     2101 ccgcgaccaa ataactggtt actattttgc cagttgagca tgaggagtcg ctggtcacgc
     2161 cagtaataaa tctgaccagt tagcagggct gaaatgatga tgccgactgt aaagaagact
     2221 gctagaatga gtttgacttt catgaaacct agagccaaag caaagtaaag tagagttggt
     2281 agtgcgaatt gtaccgcagc caatacccag aatttttgga tgataaattt tttgaaacta
     2341 ataggaagcg ttcgaatgaa atgataattt tccttttcca atgacatggc tactccgatg
     2401 aaggttgtag aaccagcaaa tagactgcca agcaagaatc cagctaatag agcaatacca
     2461 aagaaatccc attcaactga acttagacca ccattctccg tgaaacggct aaaacttgga
     2521 aaaagtgcca cccccatgat gataggctgt atcatggttt ggaccatgag gttgctatct
     2581 ttaagagtag ataggtggtg tttcactaaa gcctgattga gattgctagg aatcttggca
     2641 gacttagcat tattggtccg ttttgtcgaa gcattttcaa tcgccaaaac ttgattaaag
     2701 tagttgggaa tgacagtttt aaacgcaaac gtaataagtc caaacatcaa aatgaaagga
     2761 agtccaaaat gaaggagtgt ttctagtgat atagtatggc tgaccaagta atggaatcca
     2821 gcaaatatag gtatgatagg aaaatcaaca aagccaccgg attcgagtga aacggtctgc
     2881 tgggattgca ggaacatgag cgcagcaaaa gccagcaagg aagaacctgt catcaggatt
     2941 gtagaaatca atgttttacg agggcttttt gtcagaactt ccccaacaaa gtgcatgata
     3001 atcagattga ctaaattaac taaaatccag agaatcaaaa aggaaggaat ggaagctaag
     3061 gcgaggagcg gaccgccaat ttgccagtaa gtgattagaa gtaaagacag acacggcatg
     3121 aggaagggta ggaccatccc ttgtgcagag aggattttag cgaggaagac ttcttgtggc
     3181 ttcaggggaa gtgctaaata caattttgta tccttactat cgtagaaaac ggagaagaaa
     3241 cctgtaaaac cgtagacaat ggcaataatg gtaaagagcg ctagttgcag agaaaagaaa
     3301 ccgatagact gactataatc tactcccatg aaaaagacag agtagagaag tccgaaactc
     3361 aaaaccataa atacttgttg caagaggaca cttttatagg ctgaaaagga ggcgtctttg
     3421 cgcttacttt gtttcttctt gacggaagct agaagttgag ggttggaata aagaatatta
     3481 atctttacta gttcccaaat gatggattta ctcatacttc ctcacctgcc ttcacttgtt
     3541 ggcgtccagc taattccaaa tagatggtct ccaaatcttt atctggatac tgtgatttga
     3601 gttcatcaag acttcctacg aaaatgagtt gcccttttcg gagaatagca atgcggtcac
     3661 agagttgttc agccactgaa aggacgtgtg tagaaaatag aacggtgtga ccagattgag
     3721 catgttcttt catcatttgt tttaggtcga aagaggcctg aggatccagt ccagttaggg
     3781 gttcatccaa aatccaaata tcagggttag ggatcaatgc accaataata atggttttct
     3841 gacgcatacc atgtgaaaaa ctgtcaatag gctcatgttg gcgcgctgtc atatcaaata
     3901 gactagatag tttagcgata cggtcatcaa ctgtatcctt ttctacacca tagaccttgc
     3961 ccataaagtg ccagtattca aatgctgtta agtgtaggaa gatgtctggc gaatctggaa
     4021 cataggctat ccgttttttg acttcatcgc ggttctcctc taggtttaaa ccatcaacag
     4081 agatagttcc ataactggct tcgattatcg aagtcagtag actgattgtc gttgtttttc
     4141 ctgccccatt gtgaccaatt aaaccgaaaa tctcgccgct ttcaattgtc aaatttaggt
     4201 catcaagtgc gattgtttcg ccgtatgttt ttgtgatatg gtcaaattgt atcatagtaa
     4261 cctccttgtt attcgtgaac taaaagtagg ggcttgctag gtattccaag ccttattcca
     4321 ctgttcttcg aataatatat acaattaatt acatttatta tactgctgaa ttagtacaaa
     4381 agcaatagtt tctatcaata tttttgtagt atggatgcgg atatattgca agaagtcgag
     4441 tgtaaaatgg aatgcaataa gctcgattat cagaaaattt gctataatag atctatgaac
     4501 gatttgatca agcataaatt ggagttacta ccagatagcc ctggctgtta cctccataaa
     4561 aacaagtacg gtaagattat ctatgtgggc aaggccaaaa acctacgcaa tcgggtgcgg
     4621 tcttattttc gtggtgccca tgataccaag acagaggctc tagtggctga aattgccgat
     4681 tttgaattta tcgtgacgga ttccaacatc gaggccctct tgctagaaat caatctgatt
     4741 caggaaaaca agccacgcta taacatcatg ctcaaggatg acaagtctta tcccttcatc
     4801 aagattacca aggaacgtca tccacggctg ctcattactc ggcagattaa gaaggatggt
     4861 ggtcagtatt ttggtcccta tccagatgtg ggtgcggcca accagaccct caaactattg
     4921 gagcgcctct atcctttccg caagtgtaaa ttgcctgaga acaagtattg tctttattat
     4981 catttggggc aatgtttggc tcatggagac aatatgccca gcctgtctga ctatgacaag
     5041 atggccaagg aagtggccca gttcttgaca ggtcatgatg ataagattat caaggaagtg
     5101 caggacaaga tgaaggcagc tgctggcaat ttggaatttg aaaaggctgc ggaataccgg
     5161 gatgtcctcc aatccatttc aaccctgcgg accaagcaac gtgtgatggc tcatgacttg
     5221 cagaatcgag atgtctttgg ctactacgta gacaagggct ggatgtgtgt gcaggttttc
     5281 tttgttcggc aggggaaact gattgagcgg aatgtcaatc tttttccata ctataatgat
     5341 gcgggcgaag actttttgac ctacatcggt cagttttaca gggaccagca acatttgatt
     5401 ccctcagagg tcttgatacc gcaggatatt gaccaagaag ccgtagaagc tctggtagat
     5461 accaaggtca tcaagcccca gcgtggcgag aagaagcaac tcatcaatct ggcaaccaag
     5521 aatgcgcgtg tcagtctgga gcagaagttt aatcttttgg agaaaaatct ggagaagacc
     5581 tacggtgcgg tggagaatat cggtcagctt ttggggattc cgacgcctgt gcggattgag
     5641 gctttcgata actccaatat tatggggact agtcctgtgt cggctatggt tgtctttgaa
     5701 aatggggtgc ctaataaaaa agaataccgc aagtacaaga ttaatacggt tgagggaccg
     5761 gatgactatg cttccatgcg ggaagttttg cagcggcggt acagtcgggt gctgcgggac
     5821 ggtttgacac cgcctgattt gattatcatt gacggtggtc aggggcaggt caatgtcgcc
     5881 aagcaggtca tcgagcagga gttgggtatg tccattccca ttgcaggttt gcagaagaat
     5941 gacaagcacc agacacacga attgctcttt ggtaatccgc tggaagtagt tgagttgcct
     6001 cgcaattcac aggaattttt cctcctgcat cggattcaag atgaggttca ccgctttgct
     6061 attgagtttc atcgtcaggt tcggtcaaaa aattccttct catccaaatt ggacggcata
     6121 gaaggcttgg gaccaaaacg caagcagact ttgatgaagc atttcaagtc tattggcaat
     6181 atccagtcgg ccagtctaca agaaatcgca gaagcaggag tgccgtataa agtagcggaa
     6241 aaggtcaagg aaagcctttc ttcaaaggat gagatttgaa aacattccca taatgtgtta
     6301 gaataaacta tcaatgacta aataaggaga aagtaatggc ttttggtgaa gaaaaacaca
     6361 aaaaaacaac atttgagaaa gtgactttag taatcgttgt cgtgatggtt gtagcgacat
     6421 tggctggctt gattttacca gctattaatg cattgatgaa ttaagaacct gtattcactg
     6481 ttcagcactt ctatactaag gctagttttt aagcactcat cgttagtttt tttcaaaata
     6541 cagtcagtat tttgaaaaaa ccaccttgat tggctaaaaa cgatttctta tatataagca
     6601 cttcgcttgt gaatacaggt ctaaaacgct tttaagcgtt tttttctagg aaagaatagg
     6661 gtaaattatg agtatgtttt tagatactgc caagattaag gtcaaggcag ggaaaggtgg
     6721 cgacgggatg gtcgccttcc gccgtgaaaa gtatgtacct aatggcggtc cttggggcgg
     6781 tgatggtggt catggtggaa atgttgtctt cgttgtagat gaaggcttgc ggaccttgat
     6841 ggacttccgt tacaatcgtc gctttaaggc tgatgatggt gaaaaaggga tgaccaaagg
     6901 tatgcacggt cgaggagcgg aagatttaat tgttcgtgta ccgcagggaa caactgtgcg
     6961 tgacgctgat acaggtaaaa tcattacaga cctggttgag aatgggcagg aatttgtcat
     7021 tgcccacggt ggtcgtggtg gtcgtggaaa tattcgtttt gcgacaccta agaatccagc
     7081 gcctgagatt tctgaaaatg gagaaccagg tgaggagcgc aatcttgaat tagaattgaa
     7141 agtgttggct gatgtaggcc ttgtaggttt cccatcagtt ggaaaatcaa cgcttctcag
     7201 tgttattaca gcagctaaac ctaaaattgg tgcctaccat tttacaacca ttgtgccaaa
     7261 tttgggaatg gttcggacca agtctggtga gtcatttgca gtggctgatt tgcctggctt
     7321 gattgaaggt gctagtcaag gtgttggatt gggaacgcaa ttcctacgtc atattgagcg
     7381 gacacgtgtt atcttgcatg ttttggatat gtcagcaagt gaaggtcgtg atccttacga
     7441 ggactatgta gccatcaaca atgaattgga aacctataat cttcgtttaa tggagcgccc
     7501 tcaaattatt gttgccaaca agatggacat gccagaggca gaagaacatt tggaagagtt
     7561 caagaaaaaa ttggcaacca actatgatga gtttgaagaa ttgccacaga ttttcccaat
     7621 ttctggtatt gctcaccaag gtctggaaaa tctactagaa gctacagctg agttgcttga
     7681 gaaaacgcca gaattcttgc tctacgacga atcagatttc caagaagaag aggcttacta
     7741 tggctttaac ccagatgaac cagaatttgc aatcagtcgt gcagacgatg caagttggat
     7801 tctatctggt gacaagctgg aaaagctctt caccatgacc aacttcgatc gcgacgaatc
     7861 tgtcatgaaa tttgctcgtc agttacgtgg aatgggtgtc gatgaagccc tccgtgcgcg
     7921 tggtgccaaa gacggcgaca tcgtccgtat tggcaagttc gaatttgagt tcgttgatta
     7981 acgtagcagt ttgactgcaa gttaacttgc tagttaaact acgccaagtc ctatgggatc
     8041 ttggctagct accttactaa cttcacccaa atggtggtat caaccatttg ggttccgtgt
     8101 cgtaactttg gaatcacatc aaaatcctaa aggacttgat gtgatacggt agccgctatg
     8161 gcggactacc taccaacctt actaattccg cacaggcagt ggtatcgact gcctgtactc
     8221 catatcgtaa cctgtccggt aagttagtct agtatgaact tagaaattcg agagcagact
     8281 atagctttac aaatttcgtt cagttggtga cagtcgtttg tgagcaatct taaaaaaaat
     8341 agttggaggt ctgtatgggt gataagccaa tatccttcaa ggataagtat ggaaattttg
     8401 tctcagcagc cgatgtttgg aatgctgaaa aattagaaga actctttaac aggctcaatc
     8461 ccaatcgcaa actccgtttg gaacgtgagc gtttggcaag agagcaagaa aaggaataac
     8521 gtcaaaatct gcttgttgta tcagaaaaca ggcagatttt tttaaaattt attgactatt
     8581 tattattggt tatatgtata agaatacaag atatggagct aatatttttg cggtgtcggt
     8641 aattttatag aaattctcaa aagtgaaatt tcttaaaaaa tatgtaaaaa ctatgaatat
     8701 actggtttct tcttgaattg aagcgaattc ataatgtttt tttgaggaat tttataatat
     8761 tacttggcat ttaaagttat ttgtagtata atacctcgaa tgattgcggg agttttcaag
     8821 gctttgatac aaagagtaga aaatttgtgt aattaaatta atatttatat gggggatttt
     8881 ttatgcgtag atcaaataaa aaatcatttg actggtacgg tacgaaacaa caattttcga
     8941 ttcgtaagta tcattttggg gcagcaagcg ttttgcttgg tgtgtcgtta gttttaggtg
     9001 ctggtgcaca ggttgttaag gctgatgaaa ctgttgcttc atcagaacca actattgcca
     9061 gtagtgtagc gcctgcttca acagaagcgg ttgcagaaga agcagaaaaa acaaatgctg
     9121 aaaatacgag tgcagtagct acgacttcaa cagaagttga aaaagcgaaa gctgttcttg
     9181 aacaggtaac atcagaatca ccacttttgg ctggtcttgg tcaaaaagag ttggctaaaa
     9241 ctgaagatgc aactcttgca aaagctatag aggatgctca aacaaaactt gcagcagcta
     9301 aggcaatttt ggctgactca gaagcaactg ttgagcaagt tgaagcgcaa gtcgcagcgg
     9361 ttaaagtagc caacgaggcg ctagggaatg aattgcaaaa atacactgta gatggtctct
     9421 tgacagcggc tcttgataca gtagcacctg atacaactgc atcaacattg aaagttggtg
     9481 atggcgaagg tacccttcta gatagcacta caacagcaac gccttcaatg gctgagccaa
     9541 atggtgcagc aattgctcca catacacttc gaactcaaga tggaattaaa gcgacatcag
     9601 agccaaattg gtatactttt gaatcgtacg atttgtactc atataataaa aatatggcta
     9661 gctcaactta taaaggagct gaagttgatg cctacattcg ttactctttg gataatgatt
     9721 cgtcaacaac tgctgtttta gcagagttgg taagtaggac aactggtgat gtgttagaga
     9781 aatatacgat tgaaccgggc gagagtgtta cgttttcaca tccgacaaaa gttaatgcta
     9841 ataatagcaa tataactgtg acttatgata cctcattagc ttctgctaat actcctggag
     9901 cattgaaatt ctctgctaat gatgatgttt attcaacaat tattgtacct gcttatcaga
     9961 ttaatacaac tcgttacgtc actgaaagtg gcaaagtttt ggcaacctat ggtcttcaaa
    10021 ctattgcagg acaggtagtt actccatctt ctgttcgtgt atttactggg tatgattatg
    10081 tggcaactac aactaaagcc gttcaaggtc catatccaaa gggaacggta taccttgctg
    10141 gtacggttca aaaggataca gtacaatata aagttattcg tgaaattgtg gagaacgacc
    10201 aagcagttct taaattctat tatttagatc ctacctataa gggtgaagta gattggagag
    10261 gaactgatac gactgggttt attgagttgc ttacaacttc cccaacaacc tataaagttg
    10321 gtactatata cgattacaat attaattcaa aaattacagc tccatttact attgatccta
    10381 ccaagaatgt tatggttttc aaggaaagtg aacagaacga gcaaggtagc aaatatcgcg
    10441 tcattgctca atggtcagga gatgaaacca ctaaaggtat atatggaaaa atctatatcg
    10501 ctactcaggt ttggacgact aaattgggaa caaacgagtg gggatggttt gactattctg
    10561 atgaccaagc tggtataaaa tttaataaca aaggtttttg gccggcaggt gttcaaaata
    10621 cacttcgaaa tgctactcca gctacagctg tagagactac ttatatctac aaagaaagtt
    10681 ccaagtatgg tgatgtcatt gttgagtact acgatactga cggaaaacaa attgtaaatt
    10741 cagttgtaga tactcctaag tcagctcttg gcacagagta taatacagat gtggaccgta
    10801 gaccagccag cttggttgct gctgatggga cagtctactt ctacaaagaa gttaagtctg
    10861 attcagctaa gacaaccggt acagtagttg caggtacgac aactgttaag tatgtttacg
    10921 aaaaagctgg tagcgttaat gttaacttcg ttgacatcaa tggtaaagta atcaaagctc
    10981 ctgtttcaga tgaaaaagat gcgaaacctg gttacaatta tgataccgac ttggatcaga
    11041 aattagcttc catcactttt gaaggcaagg aatacaaact tgttcctgct ggtgattatc
    11101 cggttggtaa agttggcaag ggaaataact tgattgaagt tggtaataat actgcgaaag
    11161 gtattgaccc aacaacaggc aaaattgaag ccggtgttaa caaagaagtt acctatgtct
    11221 atagagcagt gacaggttct gtagttgtaa attacaaaga tacagaaggt aatgtgatta
    11281 aagatccaga aacggatgtg tctgatgcac cggttggaga tgcttatact acaactgaca
    11341 agaaaccaaa cgaaatcatc acaaaagatg gatcacgcta tgttcttgtt ccatctaaga
    11401 cagatggtga ggaaaatggt aaagttatcg aaggaacaat cacagtaact tatgtttacc
    11461 agaaagttgc aaactggatt ccagagattc caaatgtacc agaaacagac cgtccaaaag
    11521 taccttaccc atttgaccca acagagccag acgagccaat cgatccaacg acaccaggaa
    11581 caaatggcga ggttccaaat attccttacg ttccaggata tacaccggtt gatcctaagg
    11641 ataacacgcc gttgaaacca attgatccaa atgatccagg taagggttat gtaccaccaa
    11701 caccagaaaa tccaggtgtt gatacaccaa ttccttatgt tccagttaaa aaagtcgtaa
    11761 ctaaccacgt tgatgaagag ggtaacccta ttgcaccgca agaagaggga acaaaaccaa
    11821 acaaatcaat cccaggttac gagttcacag gtaaaactgt tactgacgaa gatggcaaca
    11881 caactcacat ctacaagaaa acaccagaag ttaagaatgg tacagttgtt gttaactatg
    11941 taacagaaga tggcacagtt atcaaggaac ctgtaacaga tacaccaact tctccagaag
    12001 gcacaccata cgacactaca gacaacaaac ctaagacaat cactttcaaa ggtgaagagt
    12061 atgaattggt tcgtgttgac ggtacagaaa acggtaaagt tgtagaaggt gaaacagttg
    12121 tgacttacgt ttaccgtaaa gtcgaaacac ctgctaagaa agttgtaact aaccacgttg
    12181 atgaagaggg taaccctgtt gcgccgcaag aagagggaac aaaaccaaac aaatcaatcc
    12241 caggttacga atttacaggt aaaactgtta ctgacgaaga tggcaacaca actcacatct
    12301 acaagaaaac acctgctaag aaagttgtga ctaaccacgt tgatgaagaa ggtaacccta
    12361 ttgctccaca agaggatggg acaacaccaa aacgtcaaat ttcaggttac gagtatgtgc
    12421 gtactgtagt tgatgaagaa ggtaacacga cacatattta tcgcaaactt tctaataaac
    12481 caacaacacc tgagaaggaa actcctgcaa aacctcaagc aggtaaaacc gcttcaggta
    12541 aagctcaatt gccaaatact ggtgaggctt catctgtggc aggtgcgctt ggtacagcaa
    12601 tgcttgtcgc aacacttgcg tttgcaagaa aacgtcgtcg taacgaagat tagtcaaaat
    12661 tctttataca gactttattc ccccacatag aaagtataag aattgtacgt aacatgcagg
    12721 attgcctttc cgaaaaaatg aggctgggca aaaagtccag agttacatct tagagttcgc
    12781 tccatttcca acctccaaca gtcactactc tgactgttgg agctgtgtgg gggtgggaga
    12841 cgagctcttt ttttattcgg tcgagttctt tctcgctccc atttttttgt cttattttga
    12901 tatactagat atagtatatt caacgaaagc atgagaattt gatatgaaat tagtctatac
    12961 agatattcgc aatcctctga cgcagtattt gacagaacag acagcaacat ttgccgagca
    13021 gggcaaacgt gttttttata ttgctccaaa ctctctatcc tttgagatgg aacgcaaggt
    13081 cttggaatac ctgcctgaac aggcaacttt tgatattatc gtgacccgtt ttgggcaatt
    13141 ggcccgctat ttgatgattg ataggaaaga agcaggtcaa ccgctggatg atgttggtct
    13201 ggcaatgatt ttctttcgtg ttctatcgca atttgaagat ggcgacttga aagtctatgg
    13261 tcgtttacag acagattttg gtttcattaa ccagctagtt gctttataca aagaattgca
    13321 acgggcaaat atgtctattt tggacttgga agccatggag tcaccagata agcaggctga
    13381 tttggtaaag atttttctgg ctgtaacaga cattttgtcc aaagaaggct ttgagcatca
    13441 gtctaagtta gcacagttga ctggcttggt agaaactggt cagttggatg agcagttgaa
    13501 gaacattgtg ctggtggtag acggattttc tcgtttttcg gcagaagaag aagctttagt
    13561 aagtgcttta aatgaacggg tgtcggaaat cctgattggt gtatatgcca gcaagaaagc
    13621 tgtgcaagcc acctatgcgg aaggcaacgt ctatcaagcc aacgttgact ttttacgtca
    13681 gttatcagcg cagttccaga ctaaggcaac ttatattggt caagagccgg tcttggacag
    13741 tatcggtaaa ttttcaaaga atatggaagc ctattatgac tacagcggga ccatgataga
    13801 cttgactcca gcagaccaag aaaaaatcca actctgggag gttgttaacc aaaaagaaga
    13861 agtggagcaa gttgcgactg caattcgtca gcatgtgcat caaggtgctc gctataaaga
    13921 catcttgttg ctcttgggtg acgtggatag ctacaagttg cagattggca agatttttga
    13981 caagtatgac attccttact atttcggtaa ggcagaggag atgagtcatc atccgttggt
    14041 ccattttgtg gagtccttgg agcgcttgcg tcgctatcgt tttcgtgcgg aagacctgct
    14101 caatctcctc aaatctggtt tgtacgccag catttcccaa aaggagctgg acctatttga
    14161 gtcttacatc ctttttgcgg atatgaaggg gcaggctgct ttttcgaggg ctttttcggt
    14221 caatggcaga gcagactatg atgctgaagt catcaaggag aaaaggcttg tctatgattt
    14281 gactgtcttg gaacccctac gtgctaagat tatggaacct ttgaaccagc tgtttaaggc
    14341 tggaccacaa tctggaactg ccttgcttga gaaatttatg gcatttttgg aggcaattga
    14401 tcttcctaaa aatatggaaa aaatgtctcg aaatttgagt gaagtagagc aagaaaaaga
    14461 agagcaggtc tggaaaagtt ttacccatct tcttgagaat tttcatcaga ttttcggaaa
    14521 agaaaagttg aaaatggatg attttctggc tattttacag gctggaatgc aggccagcca
    14581 ctatcgtacc gttcctgcaa cagttgatgt ggtcaatgtc aaatcctatg atttgatcga
    14641 gccgcacact gcaaagtatg tttatgctat cggaatgggt cagtcaaatt ttccaaaagt
    14701 tgccaagaat accagtctat tgacagaaga agagatggaa aaagtcaatc ttgtctcggc
    14761 tagttcctca cgtttcgatt tggtcagccg agagaatatc aagaagaacc atgctgctat
    14821 gatgtctctg cttaattctg cgacggaaca gttagtcatt tctactcctc agatttataa
    14881 cgaaggcgaa gatagtctct ccccatatat caagattctc caaaaaatgg ggttgaaatc
    14941 cgaagaacgt ggtcggatta aaacacttag tccacaagac atcggtcact acaagagtct
    15001 cttatcccgt ttgattgagt cggaaagacc aagccttgaa acagaggagt gggaagggca
    15061 gagggccttc tggacagtct tggttcgcca tttgaagaag aaattggagt cgcaaagcat
    15121 tgaaattccg accattactg gtgatattgc ttctaaacaa ctttcagatg aaaccttggc
    15181 tgctttatat ccagaggata agccgctcaa tctttctgca tccagcttga ccaatttcta
    15241 caataaccaa tatctttact ttgtccgtaa tgttcttcgc ctgcgggaac aggaatccat
    15301 ccatccgact gcctttcagc atggtttgtt cttgcatcgg atttttgaac gagtggtcat
    15361 ggaccaatct gagctagatt ttgatcaaaa agtggacaag gcaattctgc gtacgcgtga
    15421 cgaggcagaa tttgctatgt tttataacca ggatgcggat gctcgttata cggaggaggt
    15481 gctggataag attgctcgtt ccagtgcgac tattttgcgg gataatgatt tggttgaaat
    15541 tgatggccag gaaaagagtt tccgtcagga taaggcgctg gtttttgacc ttcaaaatgg
    15601 caagagtgtg catgtaaatg gtaccattga ccgcttggat accttacaaa tcaatcaggc
    15661 tgtcggtgtt gtggattaca agtccagcga ccaatctttt tcagttgggg atttttataa
    15721 tggtctcaaa cctcagttgg tgacctactt ggcagcctta caagagctgg atgaaaccaa
    15781 ggataaacct gtttttgggg ctatgtattt gcatttgcag gatccgatta tcaaattaaa
    15841 agacacgaag aatttagaac agctagaagg agctgccaat actagcttgg tttacaaggg
    15901 gcttttcttg aaggaggaaa gtctggggct caatcatttt tatcagactc gtaaccaact
    15961 ctacacggaa gatgagtttg cggttttatt gaaccacaac caagaactat acaaacaagc
    16021 tgccatggac attctggctg gtcgctttgc tattaaccct tataccaaag atgggcgttc
    16081 ggtggcaggt gagcagctga aggcaatcac tggttttgag gcggatcggc acatgggcat
    16141 ggcacggcgg ttggtcaaag aggccaagcg tcaagattgg atggaacgaa tgaaaggagg
    16201 tcaggactaa tggcttttga acaattttta agcgcggaag aaatcaaggc tgtgcagctg
    16261 gcggaagccc attctgataa gcagcaaaaa cgcacagctg agcagattga agctatctac
    16321 acgcacggtc agaatgttct ggtctctgca tcggctgggt caggaaagac tttcgtcatg
    16381 gttcaacgga ttttggataa gttgaagcgt ggtataggga ttgaccagct ctttatctcg
    16441 acctttacag tcaaggcggc tggtgaattg aaggagcgga ttgagaaaaa gctcaatgaa
    16501 actattgcgg agacgaccga tatggaattg cgtcggcatt tgtcggccca gttggcagat
    16561 ttgactaagg cggatattgg gaccatggac tcctttacgc agaaattggt gaccacctat
    16621 ggttatagcc ttggtatttc tccgcagttt cggattttac aggatgagac tgaaaaagcg
    16681 agtctgaaaa aagaggtttt tgaccagctc tttgcagatt atcttgaaga ggatgaaaat
    16741 ggtgcattcc gcaaactggt tcgcaatttt tcgggcaacc gcaaggataa tagtggtttc
    16801 cgtcaggttg tttatcaggt gcatgatttt agccaatcga cgagcagtcc aactaaatgg
    16861 ctgaaagaac aggctgttca agctgatttg tacagtcaag agcgtataga gcagatgcta
    16921 gagcaaggct ttaaggaaaa agtgttagac aagctctatc aagctgcaga tttcttccgc
    16981 taccatgtgg aatggggcag aaatgacttt gggtctgcta aatattttgc aaatgtggaa
    17041 gaagtcttgg atttgttgac aggtttagat agtctggacc agaaggactt gatggaacgg
    17101 gttgaaagaa ttcttctcat caataatcag tccagaggca agggcctgac caatgccaat
    17161 cgaccaaaag atgagcattt gatagccttt aaagaagaat acaatgctgg taagagccag
    17221 attatctcag aactacgaga tttgggtcag gaagtttatg aattgaccct gctgaaagac
    17281 tatcaggttc aagctttgcc actactgata ttattacgtg actttgtctt ggatttttcg
    17341 caggcttatc tggatgtcaa aatcaaggaa gcagcctttg aatttggcga cattgggcat
    17401 ttcgctattc gtattttaga agaaaatgcg gacattcgcc agtttttcca agagaaatat
    17461 cacgaagtca tggtggacga gtaccaggat aacaaccata gccaagagcg aatgctggac
    17521 ctgctgtcta acggtcacaa ccgctttatg gtgggtgata ttaagcagtc catctatcga
    17581 ttccgtcagg cggatccgat gattttccaa gagaaatttg aactgtatca ggcaaatcct
    17641 cagtctggga aattgatttt gctcaaggaa aatttccgta gtcagattga agtcttggag
    17701 gcaacaaatg ctattttcac gcgcctgatg gaccgtcaag taggggaaat caagtatgac
    17761 gacacccaca gtctagtggc tggtagtcct ggtcaaaaaa ttgcccagcc caagaatgag
    17821 atggaatact tgatttacga tcagcaggat agcgcaaact cttcaacaga tgctgaggaa
    17881 gaaacacctc tgactgctgg tgaaattgag gtcgttgcaa aagagattat tcgtcttcac
    17941 aatgaagaag gagcagactt caaggacatc actctcttgg tacaaaagcg gacgcacaat
    18001 gacctcatta tgtccatttt tgaaaaacat gggattccaa ttgtggcaga tggcggagca
    18061 gcctcctatc tgcaatcttt agaagtcatg atcatgctgg ataccttgcg ggttatcaat
    18121 aatccactca atgactatgc cttggttgcc ctgcttaaat cacctatgtt ccgattcgat
    18181 gaagatgaac tgacacggat ttccttgcag gccgggacag gtttctttta ccagaaaatg
    18241 gaaatagccc agcaagcaag tgggcaacat cctgaactga tgtcagaaaa gttgaagaag
    18301 aaaatcacgg atttcttgtc tattttggaa aattggcgtg cctatgccaa actgcattct
    18361 atttatgaca tgatttggaa gatgttcaat gaaaaattct actatgacta tgtcggtgcg
    18421 cttccaaatg gcagcaagcg tcaggccaat ctatacgcac ttggtctgcg tgccaaccag
    18481 tttgaaaaaa caggctacaa gggattgtct cgcttcatcg ccatgattga tcgtgcctta
    18541 gcaaatgaca aggacttggc agatgtacaa gagtttctac cgcaaaatgc tgtacagctt
    18601 atgactattc acaagtcaaa aggtttggag ttcaagtatg tcttcctcat gaacatcgat
    18661 aagcgattta acttggaaga ccattaccaa tcagtcatca tcagccggaa aaatggtcta
    18721 ggtatccaat atttagcaga tatgaaagat aaggtaaata gcccattacc tcaggtgcga
    18781 gtcttaatga acaccctccc ttatcaaaat aatctccaag agctaaaaat tgccaatctt
    18841 tcggaacaaa tgcggttgct ttatgttgca ctaacacgtg ctgagaagaa gctgtatctg
    18901 gttggaaagg gtaatgctga caagttagct gaaaaatacg atggcaaaaa ggaaaatggc
    18961 gtactagccc aatcaactcg tgaaagtatg gcgaccttcc aagactggat tctagccatt
    19021 gatgaggcct tctcaggaga agacttgcac ttcaagaaag tctttgtgac ggatgaggat
    19081 ttgacagagg agaagattgg taaacttaca ttgaagagta agctagaaga cgccagcctt
    19141 aaagatattc gtcaatcaga agacatcgcc caggccttgg accagttgtc ttctgtccaa
    19201 gagttgaacg aacgctataa ggctgctata gaattgccaa gtttacggac tccaagtcaa
    19261 atcaagaagc tctatgagcc tattttggaa caagaaggca tggaagttat ggaaaaatac
    19321 cagcccaaac ggaccttcaa cttgccagat ttctccaaga aaccaaaaat cactggagcc
    19381 caagtcggtt cagcagtgca tgaactcatg caacgcttgg atctgtcttg gttggtgaca
    19441 gaagatacgg taagagcagc cctagaagct gttcatgctg agcaagcgat taaagataaa
    19501 atcaatgttc agatgatttt ggatttcttt gatacagact taggaagaga aattctagcc
    19561 aatacggaca aactccaccg agaagctcca tttgcaagtt tgcagacaga ttctgtatct
    19621 caggaaaact ttgtccttcg tgggattatc gatggctacc tactgtatga tgatcatatt
    19681 gtcctctttg attacaagac agacaaatat gaccaaccaa tccaactcag ccaacgttac
    19741 caagctcaaa tgcaactcta tgcggaggca ttgaaaaaag cctacaagat agatcgtgta
    19801 gactgccatt tgattttgct tggtggggag agaatagaag tggtcgaagt caacatatag
    19861 tcatttagtt tttcttttat tacttcgtta actcgctttg ccgtactcca gtactgtctg
    19921 cagctcgttg cctagtacta aaagtaaact aaaagactat aaataaatta aaagcgagtg
    19981 gttaaactcg ctttttctgt ttggttagat tgagtccgaa tgggacaagg ttctcttctt
    20041 ttttcaaaat ccgctggata ttttccttgt gacggatgat gacaaaactg ccaagaaaga
    20101 cgataatcac tgtaaagagc cagtcgtagc ttggcaggat gattcctatt gctggaaata
    20161 gcagagctcc taagattgct aaagctgctg ctaagacgct agagaaggaa accatggacg
    20221 tcaagtagag tgaactggca aagattagaa cgagatagag gcaaaaagca ggtgcgacgc
    20281 ccagaagcat accagcagat gttgcaaccg cctttccacc tttgaattgg gcaaagatag
    20341 ggaaagtgtg tcccagtaca gccattaacc caaatacaat cggagaaatt ccttgggcat
    20401 gaaagatcag cggaagcaag gctgccaacg ttcccttgag aaaatcaatt acaaatacaa
    20461 tcgtaccagc ctttggacct aaaatacgga atgtgttggt tgttccagta tttcccgaac
    20521 catgctcacg aatgttgata ttgaaaaaag tttgacctat ccaaagtcct gacgggatag
    20581 atcccaacaa atatgcaata aatagtaaaa taagattgac taacatgttt tcattatagc
    20641 atattttcat ctaatttagt ccaaaatctt attttgtgag ctgtctcagc cgataggtaa
    20701 cagaaatatt ttgcaaaaat gctaaaaaac ttgtaatata gaaaggatga taagtatgga
    20761 ggtcagtttt ggctaagaaa gagattgata taaataatta caatgacgat gccattcagg
    20821 tattggaagg gctagatgcc gttcgcaaac gccctggtat gtacatcggc tccacagacg
    20881 gaaatggctt gcaccacatg gtctgggaga ttgtcgataa cgctgtcgat gaagccctgt
    20941 ctggtttcgg tgaccgaatt gacgtgacta ttaacaagga cggtagtctg tccgtttccg
    21001 accgtggacg cgggatgccc gttggtatgc atgcaacagg caagccaaca gttgaagtca
    21061 tcttcaccgt tctccacgca ggtggtaagt tcggtcaagg tggctacaag acttcaggtg
    21121 gtctccacgg ggttggttct tcggtggtca atgccctgtc cagctggttg gaagttgaga
    21181 ttacccgtga cggagctgtt tacaagcaac ggtttgagca gggcggaaag ccagtcacga
    21241 ccctagagaa gattggtacc gctccaaaat caaaaacagg tacaaaagtt acctttatgc
    21301 ctgacgatac catcttctca acgacggatt tcaagttcaa caccattgcc gaacgcctga
    21361 aagaatcagc cttcttgctc aagcaagtca ccatgactct gacagatgag cgaacaggtg
    21421 agcaggagga gtatcactat gaaaatggcg ttcaggactt tgtatcctac ctcaacgaag
    21481 acaaggaaac tctgacacct gtcctttatt ttgaaggaga agatgctggt ttccaagtcc
    21541 aagttgctat gcagtacaac gacggctatt cagacaatat cctgtctttt gtcaacaacg
    21601 ttcggaccaa ggacggcggt acccacgaaa caggtctcaa actagccatt accaaggcca
    21661 tgaacgacta tgctcgtaag accaacttac tcaaggaaaa ggacaagaac ttggaaggct
    21721 ctgactaccg tgaaggtttg tctgcggtcc tctctatcct tgtgccagaa gagcatttgc
    21781 agtttgaagg acagaccaag gacaagctgg gtagcccgct tgctcgccct gtggtggacg
    21841 gcattgtgtc ggacaagctg accttcttcc ttttggaaaa tggcgagcta gcatctaatc
    21901 tagttcgtaa agccattaag gcgcgtgacg cccgagaggc tgcgcgtaag gcgcgtgacg
    21961 aatcccgaaa cggtaagaaa aacaagaagg ataagggcct tttgtcaggg aaattaaccc
    22021 cagcccagtc caaaaatcca gccaaaaatg aactctatct ggtcgaggga gattcggccg
    22081 gaggttctgc caaacaaggc cgtgaccgca agtttcaagc cattctacct ttgcgtggta
    22141 aggttatcaa taccgccaag gcaaaaatgg cggacatcct caaaaacgaa gaaatcaata
    22201 ccatgattta caccattggt gcaggtgttg ggtcggattt cactatcgaa gatgtcaact
    22261 atgacaagat tattatcatg accgatgcgg acacggacgg tgctcacatt cagaccctct
    22321 tgctgacctt cttctatcgc tatatgcgac cgctagtaga ggcaggccgg gtttatatcg
    22381 cccttccgcc gctctacaag atgtccaaag gcaagggaaa ggcagaaaag attgcttatg
    22441 cttggtctga tggagaatta gaagatctcc gcaaggattt tggcaagggc tttatcctcc
    22501 agcgctacaa ggggcttggt gagatgaatg ccgatcagct ctgggaaacg accatgaacc
    22561 ctgaaacccg taccctcatc cgtgtcacca ttgaagacct agcccgtgct gaacgccgtg
    22621 tgtctgtcct catgggcgac aaggtcgagc cacgtcgcaa gtggattgaa gacaatgtga
    22681 agtttacctt ggaagagagt acggtgtttt agaaattgaa atacaattgt aagactacgt
    22741 tatgaaatta caaatttgga atgaatctta tagtctccaa tggaagggaa cctattttct
    22801 tgctttgtct gactatccta atattcaaga ttgggaatta gagaaaattg tagctttttt
    22861 agcttatgag aaactttacg gcagagagac gctaatagat tgtgaagaca aagtaatgct
    22921 tgaacaactt gtctatttat cttgttgctc acccactgca tttccattta ctccttcgaa
    22981 aaagattgtg gcctcaacat atgatgttgg tggtaattac gtttattcgg attttttaag
    23041 tcatacgtgt actgtcgaaa ctgcacaaga gattttcatg agtggtcaat tattgtccgc
    23101 tgttcgtgcg ttcaacaaaa ctcatcaaga actcgttcag gataatcgaa acgcagcagg
    23161 tgatccagaa gattattttg attatgtcat gctaggttgg tcaaatacaa gttctggcta
    23221 cagacttgca atggaaagat tactaggtag agaaccaaca gaggaagagt tggggaattc
    23281 ttttattcca ggcgtaagtt ttcattttaa gtacgacgat atagtcaatg cagatggtta
    23341 tgtttttgat ggataccacc ctgcaaaggt cagggattgt ttaagtttga aatatttgtt
    23401 tgcctgtatt gttccttcaa gtgaaaaatc tcattttgag acaattattc ccctagatat
    23461 gtcttcaaaa gtttattatt tagactatgg tcaggatggg atggcagatt ggtcccaaaa
    23521 ggtctatcaa tttgttgaaa atatagcaaa ctaatactat aaactattca attcgatgat
    23581 ttgtgatagg aatcgattgt tcctaacgcc gtgtatctgt ctttatgggc gacaaggtcg
    23641 agccacgccg caagttgatt gaagacaatg ttaagtttac cttggaggaa tcgacagctt
    23701 ttactaaata atctcaggga agttgaggtg ccatatggtt ttagaaaata aattggagat
    23761 tgaaaattcg gctgaattag cccgtcttga agaacaaatc agcaagaaaa aagcagctca
    23821 actgttcgaa aatggtcagt tattccagat agaagttgga acctttgccg gtttggcaca
    23881 cattcatcaa gctttatttg aggatattta cgactttgca ggtaagattc gtgatgtcaa
    23941 cattgccaac caaagataat tttcaattcg ctccacgtat ctttcttgag cagtctttgg
    24001 cctatatcga caagctacct cacgaaacct ttgatgaaat cgttgaaaaa tatgcagata
    24061 tgaacattgc acatccattc cgagaaggaa atggacgcag tatgcgtatc tggttggatt
    24121 gtatgctacg ggatagtttg ggtagggttg ttgactggaa tagcattgat aaagatgaat
    24181 atttcaatgc aatggttaga agccatgtgt caacaggaga gcttaaatat ctgttattgc
    24241 aagccttaac ggaagatctt ggtcaggcta cttatttcaa gggcatcgac cattcttatt
    24301 actatgaggg ttacaaccta tatcgtattg aggatttgta aatctagcat aaacaaatga
    24361 tgtgaggtgt tttatgccac taagagtaaa attaactgac cgttttcaaa aacggttgtc
    24421 tgaatgggca cgaaagcgca agccatttaa aaacaaacag gagttggaag agaaatttgg
    24481 ccaagcattg aagatttggc aatcttccaa aactcggcaa catgcagaaa acttgctatc
    24541 tgagcaagga aaattagaac attttttaca tagcacggaa cggaaactgt ctcgtatgcc
    24601 ttttggcgga gataagtttg cggctattcc aggcttgatt tccatggtgc gaagctatat
    24661 ccgtagagat tacagcaagt tacccaaagc gacaatcctc gcaattatag gtgctttgat
    24721 ttattttttc agtcctattg atgccttacc agatttcatc cttggagcag gtctacttga
    24781 cgatgccttt gtccttaatg cctgtttgaa attaatcaaa acagatgtcg atgactttag
    24841 aagctggcaa gcaagccagt ggaaggcgga agagtagcta tgataaagtt tttaagaaaa
    24901 aagccaacta tcgagcaact taagaaagtt ccttatgctt ctcagtatac agaggttcta
    24961 cgttcaattt ggcgagcaga tgtgcctaaa tacgggattt cttctacttt acaaggtgaa
    25021 ttacttcgac aattagaaaa acttcgctgg gaagctcaag caaatggcaa tgtcaattgg
    25081 tgtgaagagc actcaaacta ctgtcgattc ataaaggaga ctctctataa aggaaaactc
    25141 ctttcttctc aacagaagca agagttagtt ttaataatgg attatctaaa atcgtgtggt
    25201 gaatatgctc aagcttatca agaaaatttg attgatgatg aggaattaga aattgagaaa
    25261 ttagcatatg ttgatgacaa tctttatgat agagtagggg atatgattgc tttcttttat
    25321 cagagaactt aggtaaagaa ctaatgttta gttaaggata tcgcaacaga aattgctata
    25381 taagctctct tccgttccca ctacttaagg tgattatcaa aaaagtaaaa aagaaagaaa
    25441 atttaacttc ccaccaagaa acaaagaaag gaatgttcgg ttagtagaaa taactgaaca
    25501 cgggactgaa tcgtcccttt gtatcttaat ttatgtcaaa cattcaaaac atgtcccttg
    25561 aggacatcat gggagagcgt tttggtcgct actccaaata cattattcag gagcgggccc
    25621 tgccggacat tcgtgacggt ctcaagcccg tgcaacgtcg gattctttat tctatgaata
    25681 aggacggcaa cacttttgac aagggttacc gtaagtctgc caagtcagtc ggaaatatca
    25741 tggggaattt ccacccgcac ggtgattcct ctatttatga tgccatggtc cgcatgagtc
    25801 aggactggaa gaaccgcgag attttggtgg agatgcacgg aaacaacggt tccatggacg
    25861 gcgatccgcc agcagctatg cgttacaccg aggctcgcct ttcggaaatg gctggctatc
    25921 tcttggctga catcgagaaa aagaccgtac catttgcctg gaactttgac gatacggaaa
    25981 aagaacccac tgtgctacca gctgccttcc ctaatctctt ggtcaatgga gcgacaggaa
    26041 tttcagcagg gtacgcgact gacatcccgc cgcataatct agcggaggtc atcgatgccg
    26101 ttgtctacat gattgatcat ccaacagcta agttagaaaa gttgatggag ttcttgcctg
    26161 gaccagactt cccaacaggt gccattatcc aaggggctga cgaaatcaag aaagcctatg
    26221 aaactggtaa gggccgtgtc gttgtccgta gccgttgtga aatcgagcaa ctcaaggctg
    26281 gtaagaaaca gattgtcatt actgagattc cgtatgaagt caacaaggct gttttggtca
    26341 agaagattga tgatgtccgt gttaacaaca aggtgcctgg tattgccgag gtgcgtgatg
    26401 agtcagatcg gacaggtctg cggattgcca ttgagctgaa aaaagatagc gatgagcaaa
    26461 ccattctcaa ctacctctac aaatacaccg acctacaaat caattacaac tttaacatgg
    26521 tggcgattga taatttcaca ccgcgtcagg ttggcttgca gaagattctg tccagctaca
    26581 tcgcccaccg ccgtgagatt atcattgccc gttctaagtt tgacaaggaa aaagcagaga
    26641 aacgccttca catcgtagag ggtttaatcc gcgtcgtttc cattttggac gaggttattg
    26701 cccttattcg tgcttctgaa aacaaggcgg atgctaagga aaacctgaaa atcagctatg
    26761 agttcagcga ggagcaggca gaagcaatcg tgaccttgca actctaccgc ttgaccaata
    26821 ccgacattgt gaccttggaa aatgaagaag cagccctacg cgagcagatt cagaccttgg
    26881 cagctattat cggcgatgag cggaccatgt tcaatcttat gaagaaggaa ctgcgtgagg
    26941 tcaagaagca gttcggcaat cctcgtttga gtgaattgca ggatcaggca gaaacgattg
    27001 agattgatac tgccagtctg attgtcgagg aagaaacttt tgtcagcgtg accaaggcag
    27061 gttacatcaa acggacaagt cctcgttctt tcaatgcctc aacgcttgaa gaaatgggta
    27121 agcgggatga tgaccagctg attttcttgc agaatgccaa gacaactcag cacctcttgc
    27181 tttttaccaa tcttggaaat gttatctacc gacctgttca tgagttgaca gatattcgtt
    27241 ggaaggacat tggtgaacac ctgagccaga ctctcatgaa ctttgatacc aatgaagaga
    27301 ttatcttcgc tgaattggta gagaattttg aagaggggac ttatttcgcg gtgaccaaat
    27361 acggtcaaat caagcgtgtg gagcggaagg agttcacgcc atggcggact tacaagtcca
    27421 agtcaaccaa gtatgccaaa ctcaaagatg cagaggatgt ggttattact gtatcgcctg
    27481 tagtcttgga tgacatcatg ctcatgacag aaaagggcta cgctctgcga tttaacatcg
    27541 aagaagtgcc aatcatcggt gccaaggcgg ccggtgtcaa ggcggttaac ctcaaggacg
    27601 aggatgtggt ggctgcggcc tttatcagca ataccaactc cgtctatctc ctgacccagc
    27661 gtggtagcct taagcggatg gcgacggagg aaatccctgt gaccagccgt gccaagcgtg
    27721 gtttgcaggt gcttcgcgaa ctcaaggcta agcctcaccg tgtctttgcg gcaggtccag
    27781 tcttgacgga tcagggtgat tttgatctct ttagcacggc aaatgaagat gatacgacaa
    27841 gtcaaatcct tcacgtgcag tccaaaacag gcaaactcta tgaggttgat gtgacccagc
    27901 ttagcctgtc tgaacgcact agcaacggta gcttcatttc ggataccatt tccgatgaag
    27961 aagtcttcag agcctggata gactaaaaaa gatgaaaaga ttgctcgcaa agaagtcttt
    28021 ttgctatact gtagaggagg taaatgctat gaaaattatc aaattatttt tcagtataaa
    28081 agtctatcta tggcttgttc tgtccttcct tctgttattg tgtggtgtat ggggatacgg
    28141 ctacatctct ggtgaaaaga gtaatcagca ggaagtgagt gtccatgcgg ctattgagtc
    28201 tgtcgagcaa gtcaatgaat tggtatttct aaatacagct gtccagaaaa ttgtgaccgc
    28261 taaaaactac acggtcttat ttggtcaaga aatgcccttc tcagaaaaat cagccctctt
    28321 aattatcaag tacaaagcaa aatttggtat caaaagtcct gtatccattg aacatctttc
    28381 tgaaaatcgg tacaaaatta cccttccagc ctttgaagtc attggattgg aattagatgc
    28441 agaagaacct tataccttat atgataagag tggtgagata ctgagttttg cgacagaaga
    28501 aatcgatact gcccaactca tcacagatga atttcagtcg gtagagcaag aaaagttttt
    28561 agcagattat caggaagaca taaaagagtc agccaaaaac tactatcaaa atttatttag
    28621 tgctatctca cctgaaattc aactagaatt tgtttttaaa gagtaagagt ctggtttacc
    28681 aggctttttc ttatattcac aaaattttct gaatttttaa ttgaaaatca ctttcaaaag
    28741 tagtaaaata ttaaaaaatg aatttggaga aactatatga cagtgaacat tgactgggaa
    28801 aaccttggtt tttcttatat gaaactacct taccgcttca tcgctcattt caaaaacagc
    28861 caatggtctg aagggcagtt gaccgaagat gcggaattgc acatttcaga aagctcacca
    28921 gcccttcact atggccagca ggcttttgaa ggccttaaag cctatcgtac caaggatgga
    28981 aaactccagc tctttcgtcc agaccaaaac gctgagcgcc tgcaacggac agctgaccgc
    29041 ttgctcatgg agcctgtacc gacggatctt ttcatcaagg cttgtaaaga agtggtcaaa
    29101 gccaatgcag actacgttcc tccctatgga actggtggga ccctttatct ccgtccgctc
    29161 ctgattggtg tcggcgacat catcggcgtc aaacctgcgg aagagtacat tttcacagtt
    29221 tttgccatgc cggttggtaa ctatttcaaa ggcggcctgg ctccgaccaa cttcctcatc
    29281 caagacaagt acgaccgtgc ggcaccaaat ggaacagggg cagccaaggt tggtggtaac
    29341 tacgcggcgt cgctcttacc gggccaatat gccaaaaagc agggcttctc agatgtcatc
    29401 tacctggatc cagctaccca caccaagatt gaagaagtgg ggtctgctaa tttctttggt
    29461 atcacagctg ataacgagtt tgtcacaccg atttcaccat caatcttgcc gtctattacc
    29521 aagtattctc tcttgtactt ggcagagcat cgtctgggta tgaaggctgt ggagcgtgaa
    29581 gtccttgtcg aagaattaga ccagtttgtc gaagcaggag cttgcggaac agctgcagtt
    29641 atctcaccaa ttggtggtat ccagattgca gacaaactcc atgttttcca tagtgaaaca
    29701 gaagtaggac ctgtcactcg taaattgtat gaagaattaa caggtatcca gtttggtgat
    29761 attgaagcgc cagaaggttg gattgtcgaa gtagattaat ttcagaaggc ttgcacttgc
    29821 aagctcttct ctttttttgt agaatagtaa aagtgaggtt tgaaaatgag taaaaaagat
    29881 aaaaaaattg aaattcagat tgaagatagc aaagttcttg tcaatagaga agagttccct
    29941 ggctaccgcc ttgttatagg taaaaaagta attggagaaa ttgcagaatt ggctgaaaat
    30001 aactttgcag ttattaaaaa cggaaatacc gaaagctttt acaaaaaatt agaaaaagca
    30061 gtcggaaata ttattgaaaa ttataattta agtcactaaa agacttgtaa tagtcgctat
    30121 tttatgttag aatagtgact gttagtgtac ggagagatag cgaagaggct aaacgcggcg
    30181 gactgtaaat ccgctccttc gggttcgggg gttcgaatcc ctctctctcc attgaacagg
    30241 atacaaagga cgttaagaaa tccgtacgaa aataggaaat tgacgcagtg tgctaaacac
    30301 acagggaagt ttatcttttt cactaggatt ttagtccgtg ttcaactaag atacgagata
    30361 tgttctggtt taccagaaat ttctgtagaa aattaggaga ctgacgctga gtgttaacac
    30421 tcaaggaagg ctatctattt ttctaagaaa ttaatctcga gttcaatttc ttatgattag
    30481 taaataaatg aattgtatct attt
//
LOCUS       DBNFCO010000017        29199 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.017, whole genome shotgun sequence.
ACCESSION   DBNFCO010000017 DBNFCO010000000
VERSION     DBNFCO010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 29199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29199
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.017"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            1..104
                     /locus_tag="AC1PIV_000655"
                     /pseudo
     CDS             1..104
                     /locus_tag="AC1PIV_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355409.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
     gene            122..3856
                     /locus_tag="AC1PIV_000656"
                     /pseudo
     CDS             122..3856
                     /locus_tag="AC1PIV_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167702.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005509 - calcium ion binding [Evidence
                     IEA];
                     GO_process: GO:0018262 - isopeptide cross-linking
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SspB-related isopeptide-forming adhesin"
     gene            3857..4048
                     /locus_tag="AC1PIV_000657"
     CDS             3857..4048
                     /locus_tag="AC1PIV_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-binding protein"
                     /protein_id="HIP6611699.1"
                     /translation="MNPKSIYEKDSDQDGLTDAQELAFGTNPQSVDTDGDGQADLEEL
                     QSGHSPLVPQKELCDGLEL"
     gene            4032..4583
                     /locus_tag="AC1PIV_000658"
     CDS             4032..4583
                     /locus_tag="AC1PIV_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611700.1"
                     /translation="MAWNFDTMKEALSEMEKVDYQEFIKAFLSLELSISDRTILNQVY
                     QDYMDEDDLSLISDELRVKVDSYQDEVQADMTDILEKLYRTGEGSSFIMDLMSSNSLS
                     DTLEQYEVLDSDDYSPLSLETLQAMIQQDLAISSQDYFGDLVHLALQKDLLDQKSHFL
                     QHYVATVMEGIPQERDQRALVLD"
     gene            4632..10580
                     /locus_tag="AC1PIV_000659"
     CDS             4632..10580
                     /locus_tag="AC1PIV_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0140658 - ATP-dependent chromatin
                     remodeler activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2-related protein"
                     /protein_id="HIP6611701.1"
                     /translation="MNQEVLLQMMRATIPRDRALLEAFLYYQAEHFDEEWDSLIRQFL
                     SNRQANISPVQVLHFETDVSAFVQASPYDNAHDLLTYTQVFGQTGLQKLDKLSPSEKD
                     LVIEVALFNLATRFQLLDSNGHYQTISPDSLLQKSRGANLVNVYRVANNLADRISRDI
                     EQFLLTYEPELETRADKTVLENEETGDEHKVSSNQAIPFREDGSLIIASLDVDLSQLN
                     VQTGKTSHLPAYEELLLQRKFEILTYFDHIRNERSKVPSFKRGDFDTEMEMTPIFEGK
                     ELLTYLEADGSPYELKRTLTTVEEKELEKIGQAIRIENQEKLTQLGIELSQFDPDRVG
                     ILLDAAGRYRLKNADLALLGGYPKASVTQLALATELLQMGLSHEKVEFFFGSQLSLEE
                     LRQVAYAFLHEELSREDAEQFEKDKGNQPDLTLRDWKSKLEKAERKEVVDEEFVENPL
                     VQRVLDTYPLGSLVSYKGQDFEVVSVSDARLNGLIRIELVNDFSDIIEQNPVLYVRTW
                     EEVSQALHQPKAEPQTELEEADQELNLFSFLEEEPVQSIGLLEPDGSEKGHNDTDLEE
                     TDNQIPEEEVVETIPEIPVTDFYFPEDMTDFYPKTARDKVETNIAAIRLVKTLETGRR
                     QASTSEQELLAKYVGWGGLANDFFDDYNPKFSKEREELKSIVTDKEYSDMKQSSLTAY
                     YTDPALIRQMWDKLERDGFTGGKILDPSMGTGNFFAAMPKHLREKSELYGVELDTITG
                     AIAKHLHPNSHIEIKGFETVAFNDNSFDLVISNVPFANIRIADNRYDKPYMIHDYFVK
                     KSLDLVHDGGQVAIISSTGTMDKRTENILQDIRETTEFLGGVRLPDSAFKAIAGTSVT
                     TDMLFFQKHLNKEYVADDSAFSGSIRYDKDSRIWLNLYFDGEYNSQVLGTYEVRNFNG
                     GTLSVKGTSDDLIASVEAALHQVKAPREIDRNEVIINPDVLIKQVIDTSIPAEMRENL
                     GQYSFGYQGSTVYYRDNKGIRVGTKTEEISYYVDEEGNFKAWDTKHSQKQIDRFNALE
                     VTDNTALDVYVTDDAAKRGQFKGYYKKTVFYEAPLSDKEVARIKGMVDIRNAYQEVIA
                     IQRYYDYDKKTFNHLLGKLNRSYDSFVKRYGYLNSAVNRNLFDSDDKYSLLASLEDES
                     PVPSGNSVIYTKSLAFEKALVRPKKEVKKVHTALDALNSSLADGRGVDFDYMMSIYQV
                     ESKMNLIEELGDLIMPDPEKYLNGELTYVSRLDFLSGDVVTKLEVVDLFVKQDNQDFN
                     WSHYAGLLEAIKPARITLADIDYRIGSRWIPLSVYGKFAQETFMGNAYELSDQEVATV
                     LEVSPIDGVITYQSKFAYTYSNAMDRSLGVPASRYDSGRKIFENLLNSNQPTITKQIV
                     EGDKKKNVTDVEKTTVLRAKETHLQEFFQDFVARYPEVQQMIEDTYNSLYNRTVSKTY
                     DGSHLTIDGLAQNISLRPHQKNAIQRIVEEKRALLAHEVGSGKTLTMLGAGFKLKELG
                     MVHKPLYVVPSSLTAQFGQEIMKFFPTKKVYVTTKKDFAKAKRKQFVSRIITGDYDAI
                     VIGDSQFEKIPMSREKQVTYINDKLEQLREIKLGSDSDYTVKEAERSIKGLEHQLEEL
                     QKLERDTFIEFENLGIDFLFVDEAHHFKNIRPITGLGNVAGITNTTSKKNVDMEMKVR
                     QVQAEHGDRNVVFATGTPVSNSISELFTMMNYIQPDVLERYQVSNFDSWVGAFGNIEN
                     SMELAPTGDKYQPKKRFKKFVNLPELMRIYKETADIQTSDMLDLPVPEAKIIAVESEL
                     TQAQKYYLEELVERSDAIKSGSVAPSRDNMLKITGEARKLAIDMRLIDPAYTLSDNQK
                     ILQVVDNVERIYREGENEKATQMIFSDIGTPKSKEEGFDVYNELKDLLVDRGIPKEAI
                     AFVHDANTDDKKNSLSRKVNSGEVRILMASTEKGGTGLNVQSRMKAVHHLDVPWRPSD
                     VGRILRTFKIKKNVEVTDNGKDNF"
     gene            10561..10935
                     /locus_tag="AC1PIV_000660"
     CDS             10561..10935
                     /locus_tag="AC1PIV_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001129922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TnpV protein"
                     /protein_id="HIP6611702.1"
                     /translation="MAKTIFEEMGGKYERQGDYLIPCLTVPAEEEQPIGIWGQRHLDY
                     LKHHCKVTYTNLLTSGRLNAYLADIDRQAQERFERLIEGMKQAQGITEQLKAENALEW
                     TGCLNNIRACAREIVEKEIIFA"
     gene            11302..13221
                     /gene="tet(O)"
                     /locus_tag="AC1PIV_000661"
     CDS             11302..13221
                     /gene="tet(O)"
                     /locus_tag="AC1PIV_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032490535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(O)"
                     /protein_id="HIP6611703.1"
                     /translation="MKIINLGILAHVDAGKTTLTESLLYTSGAIAEPGSVDKGTTRTD
                     TMNLERQRGITIQTAVTSFQWEDVKVNIIDTPGHMDFLAEVYRSLSVLDGAVLLVSAK
                     DGIQAQTRILFHALQTMKIPTIFFINKIDQEGIDLPMVYQEMKAKLSSEIIVKQKVGQ
                     HPHINVTDNDDMEQWDAVIMGNDELLEKYMSGKPFKMSELEQEENRRFQNGTLFPVYH
                     GSAKNNLGIRQLIEVIASKFYSSTPEGQSELCGQVFKIEYSEKRRRFVYVRIYSGTLH
                     LRDVIKISEKEKIKITEMCVPTNGELYSSDTACSGDIVILPNDVLQLNSILGNEMLLP
                     QRKFIENPLPMLQTTIAVKKSEQREILLGALTEISDGDPLLKYYVDTTTHEIILSFLG
                     NVQMEVICAILEEKYHVEAEIKEPTVIYMERPLRKAEYTIHIEVPPNPFWASVGLSIE
                     PLPIGSGVQYESRVSLGYLNQSFQNAVMEGVLYGCEQGLYGWKVTDCKICFEYGLYYS
                     PVSTPADFRLLSPIVLEQALKKAGTELLEPYLHFEIYAPQEYLSRAYHDAPRYCADIV
                     STQVKNDEVILKGEIPARCIQEYRNDLTYFTNGQGVCLTELKGYQPAIGKFICQPRRP
                     NSRIDKVRHMFHKLA"
     gene            13276..13446
                     /locus_tag="AC1PIV_000662"
     CDS             13276..13446
                     /locus_tag="AC1PIV_000662"
                     /inference="COORDINATES: protein motif:HMM:NF025568.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HIP6611704.1"
                     /translation="MKCEWILCPVCGSKTHNKIRKDTVLENYPLYCPKCRQESLIKVD
                     NLKITVIKEPDA"
     gene            14038..14445
                     /locus_tag="AC1PIV_000663"
     CDS             14038..14445
                     /locus_tag="AC1PIV_000663"
                     /inference="COORDINATES: protein motif:HMM:TIGR02937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed RNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HIP6611705.1"
                     /translation="MDKLFIPVQGCLLEVVREQYADFYRDRERWRYLQKLDARNSLLS
                     LDGFTDSEGNPLDFIADEAADIAETVVNAVMVDRLKAALPLLSDSEQELIQAIFFDGL
                     SEREVGARLGITQSVVNKRKARILRKLRKIIEN"
     gene            14540..14965
                     /locus_tag="AC1PIV_000664"
     CDS             14540..14965
                     /locus_tag="AC1PIV_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HIP6611706.1"
                     /translation="MAYNHGREDRKWRIWKEAEEKLLRECGVDEVTIEQIRIADRADF
                     NSNRRFYRWTNDVAEYLEDMADRERQAEVNTVAELLDEIESENLYQVLVTVDGRTLKI
                     VLLKMQGYSTKEIAPLVHLTTGAIYARLDHLRKKLRKIL"
     gene            15049..15522
                     /locus_tag="AC1PIV_000665"
     CDS             15049..15522
                     /locus_tag="AC1PIV_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-like helix-turn-helix DNA-binding
                     protein"
                     /protein_id="HIP6611707.1"
                     /translation="MAYKAKAYTLREESTESGIRYFISFKDGQGEHHELEVSEQLFFE
                     FRQMERRNRNLLQWDERHREFSEVWDETLNRRALKLPKSIEEQMIEAERAELLCKAVD
                     RLPEIQRRRFLLYYEYEFNFYQIAAMEHCTASAIQKSVAVAKKKVKAEMRKYLQP"
     gene            15676..16700
                     /locus_tag="AC1PIV_000666"
                     /pseudo
     CDS             15676..16700
                     /locus_tag="AC1PIV_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015521636.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
     gene            17226..18191
                     /gene="mobV"
                     /locus_tag="AC1PIV_000667"
     CDS             17226..18191
                     /gene="mobV"
                     /locus_tag="AC1PIV_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /protein_id="HIP6611708.1"
                     /translation="MPYAILRFQKRKAGGVAACERHNERKKEAYKSNPDIDMERSKNN
                     YHLVAPPKYTYKKEINRKVAEAGCRTRKDSVMMVETLITASPEFMNQLPPEEQKAYFT
                     MALDFISERVGEQNILSAVVHMDERTPHMHLCFVPITPDNKLSAKTILGNQKSLSEWQ
                     TAYHERMSSRWNQLERGQSSMETKRKHVPTWLYKLGGRLDKQYGEIVSALSDINAFNA
                     GKKRDKALELVAAWLPEVEKFSKEIGRQQAYIDSLKEQIGQEADYAGRMRDEKYEQEL
                     KVQKANQRIFELQRTNEQMGRLLSKIPPEVLEELQRTGRNKSRER"
     gene            18199..19053
                     /locus_tag="AC1PIV_000668"
     CDS             18199..19053
                     /locus_tag="AC1PIV_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002596257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HIP6611709.1"
                     /translation="MKKQDFKVLKTKDLYPFPDNPFHVVEDETLSELAESIKEFGIVT
                     PIITRPKEDGNGYEVIAGQRRVRASELAGINTVPAFVLPLDRDRAIITLVDSNLQREN
                     ILPSERAFAYRMKSEAMKRQGFRTDLTSSQVVTKLRTDDKVAQGFGVGRMTVQRFIRL
                     TELIPPILQMVDEGKIALTPAVELSFLKKDEQENLFATMESEEATPSLSQAQRMKSMS
                     QSGQLDMDMIFSIMTEEKGNQKETLKINTSKLKKYFPKDTTPKQMEETIIRLLERELQ
                     RKRSRDSR"
     gene            19130..19360
                     /locus_tag="AC1PIV_000669"
     CDS             19130..19360
                     /locus_tag="AC1PIV_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HIP6611710.1"
                     /translation="MKEIQYEIVKEIAVLSASDSGYTKEINLISWNGREPKYDIRSFS
                     PNREKCGKGITLNADEAAALLEALQKEVNSGD"
     gene            19431..19622
                     /locus_tag="AC1PIV_000670"
     CDS             19431..19622
                     /locus_tag="AC1PIV_000670"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611711.1"
                     /translation="MGEDRKTTGRRKRIVPKGQVQMIISREYIGTQTVAEAFVPIISE
                     DIRKKIAEGDTFDNEGLSA"
     gene            19676..21559
                     /locus_tag="AC1PIV_000671"
     CDS             19676..21559
                     /locus_tag="AC1PIV_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HIP6611712.1"
                     /translation="MAGIRTENKIYEVGIYCRLSKDDGTDNESASIATQKSILTDYVK
                     RQGWHLAKTYVDDGYSGTNFQRPSFQNMIKDIENGLINCVITKDLSRLGRNYLDCGLY
                     LEVFFPEHNVRYIAVNDGVDTLNKSAMDITPFRNILNEMYSADVSVKIKSAYRARFQQ
                     GKFMGTTAPYGYVKDPADHNHLLIDDKVAHVVREIFDLALAGNGIAKIRKHINKQHIL
                     RPAAYAVEQGATGYERYFEDNEENRYIWSENSVRGILRSPIYAGNLAGYKRIAANMKS
                     KKRPSKLPEEWEVIPDTHEGIVTQEEFDTVQQLMTSRRREQNAGGFENIFSGVIKCAD
                     CGYAMRAASANRRKRPDIIDCVQYTCNNYGRYGNVMCTAHSIEARDLFNAVLADINRF
                     ADMAVNDEKAVRAIERRLTETDQSRAKSLEKEKKKLNKRLAELDRLFSSLYEDKVMER
                     ITERNFEMMSGKYQKEQLEIEARLKEVTETLNDSYEKSQGVRDFLSLIRNYQGLKELD
                     ATIINALIDKILVSEREKLADGTVRQEIKIYYKFIGFVGELHITPTKRWTALKPKNCT
                     VCGVEYVPSSGISKYCPACAKRIQREKSNESKRRSRERNRRACIELSAKNDRLTLSSE
                     MDD"
     gene            21526..22485
                     /locus_tag="AC1PIV_000672"
                     /pseudo
     CDS             21526..22485
                     /locus_tag="AC1PIV_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001071192.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            22556..22855
                     /locus_tag="AC1PIV_000673"
     CDS             22556..22855
                     /locus_tag="AC1PIV_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000194854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5962 family protein"
                     /protein_id="HIP6611713.1"
                     /translation="MGQTVEEMRYQLEEWLSQGFTSSEDRANYQTLKEQYEDETFDYS
                     FSRREITGQLEIIITSRENDFPSLDKVTKAEYLDLVAQLDDLDKRQADYYRKQLA"
     gene            22869..23159
                     /locus_tag="AC1PIV_000674"
     CDS             22869..23159
                     /locus_tag="AC1PIV_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000893084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5966 family protein"
                     /protein_id="HIP6611714.1"
                     /translation="MLEQILQSLLIIAAIGLMLFVLYRIVKVSGALFLIGLISGLVFI
                     EIYGIYLFFTERHLYSEDLAANGIWSFTGFYIALNLFLAISLSMRWWRNRIV"
     gene            23254..23892
                     /locus_tag="AC1PIV_000675"
     CDS             23254..23892
                     /locus_tag="AC1PIV_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HIP6611715.1"
                     /translation="MLNKVKARFLIGLGGLIAVSFMVMIGYTIGSQTISKQTENQIRA
                     EANKLVSKKKQEERATVLSDELVNEFLTQYFTKVQLGENNARIKPYMTDSAFSEEEAN
                     QNKAINQVYKDYMLDYRFESASIYVNTESNVALAEVTYQVTYVSDLSEQQQRTSQTET
                     KTVMLSYSKVSDKLLVNQLTIWNGKLEDMKEATDGANSSIPTIQGTTTSENN"
     gene            23932..25032
                     /locus_tag="AC1PIV_000676"
     CDS             23932..25032
                     /locus_tag="AC1PIV_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HIP6611716.1"
                     /translation="MTRIKAVKQKAILDVAESLGYSFRRLSGHIYEHPDHDSFRIFAD
                     TNTFKWFSRDIQGDVIDFVQLVAGVTFKEAVSYLETGDFEQAKLIEETYQPFQYYLHE
                     EPFQQARTYLQVVRGLSDQTINTFGRQGLLAHATYQSEPVLVLKSYDHNGTLQAASLQ
                     GLVKNEEKHDRGYLKKIMKGSHGYVGISFDIGNPKRLIFCESVIDMMSYYQLYQKQLS
                     DVRLISMEGLKLSVIAYQTLRLAAEEQGKLAFLDTVNPSRLSHYLQAIQETTTFFQTH
                     SNALTLAVDNDEAGREFCQKLSDKGLPLSQDLPPLQGLETKLDWNDIVKRQKELSLRD
                     LIQSAQTKVIRDHPPPKREHTFDVITKSSPLS"
     gene            25060..25287
                     /locus_tag="AC1PIV_000677"
     CDS             25060..25287
                     /locus_tag="AC1PIV_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002943342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5965 family protein"
                     /protein_id="HIP6611717.1"
                     /translation="MSVIERLAEKVARQEEKVSRETEKLEHYRDQLQTAMYSTFIKRQ
                     QSSQLSFHEALEQAFGKETTLHPNYRNEDTE"
     gene            25284..25673
                     /locus_tag="AC1PIV_000678"
     CDS             25284..25673
                     /locus_tag="AC1PIV_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5945 family protein"
                     /protein_id="HIP6611718.1"
                     /translation="MSKTWNFDQPLDDVKPTSSHEERAKIAALFHKQDEKPIEEVDYV
                     AAFEQQQKESESKDVQTHESKVKQSQPKKVNITSDYKQHLADTIAQNNKDISACQKQI
                     EELHQLIDEKKIQNKKLQAISVAIDDL"
     gene            25723..26013
                     /locus_tag="AC1PIV_000679"
     CDS             25723..26013
                     /locus_tag="AC1PIV_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000667954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611719.1"
                     /translation="MKFFQKKKQNQDQFKRLIHRLSEMSDSELTKVEQLLDVVFDSSF
                     KSSERVEISRDIITDEEQILDKSIQEAKNKLNTEQLEKRIEEFKQSKKPKNG"
     gene            26083..26559
                     /gene="pezA"
                     /locus_tag="AC1PIV_000680"
     CDS             26083..26559
                     /gene="pezA"
                     /locus_tag="AC1PIV_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013851913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin PezA"
                     /protein_id="HIP6611720.1"
                     /translation="MIGDNIKSLRRTHDLTQPEFAKMVGISRNSLSRYENGTSTVSTE
                     LIDRICQKFNVSYVDIVGEDKMLTPVEDYHLTLKVEVIKERGAAILSKLYRYQDSQDI
                     VFDDESNPWILMSDDLAELINTKIYLVATFDEIERYNGYLDGIERMLDMVHHRVVA"
     gene            26559..27326
                     /gene="pezT"
                     /locus_tag="AC1PIV_000681"
     CDS             26559..27326
                     /gene="pezT"
                     /locus_tag="AC1PIV_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system toxin PezT"
                     /protein_id="HIP6611721.1"
                     /translation="MRLEEFSEAEFQKALQRTIRALTRGKTIPDQPKAILLGGQSGAG
                     KTTIHRIKQKEFQGNIIIIDGDSYRSQHPNYLALQEKYGKDSVDYTKGFAGKMVEQLV
                     DELSTQGYHLLIEGTLRTTQVPRQTAQLLSSKGYQVSLAVIGTKPELSYLSTLIRYEE
                     LYAIDPTQARATPKEHHDGIVENLVDNLRELESENLFDQIQIYQRDRTCIYDSETAEG
                     SAAEVLQECLFGKWSKVEEEMVKESELLLKELLEKNK"
     gene            27327..>29199
                     /locus_tag="AC1PIV_000682"
     CDS             27327..>29199
                     /locus_tag="AC1PIV_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spaf_1101 family AAA-like ATPase"
                     /protein_id="HIP6611722.1"
                     /translation="MILKIIFFWGLELRGFNNKIKSVYRELTNTKEKFGSFHKTLIHL
                     HTPVSYDYKLFSSWTSTKYRKSTEDELFDIFFKNKKIKVDKTKFFGSFDKVIFSSPKE
                     YISFLLLAEAILKNEIEIVVVTDHNTTKGIKKLQTAVSIITRTYPTYNIHPHILHGVE
                     ISAADKLHIVCIYDHEKESWVNQWLCENIISEKDGSYQHSLTIMKDFNNQNIINYIAH
                     FNSYNILKKGSHLSGAYKRQVFTKENTRFIGVKNINSVEGSKNRLLTDFNCEPNFLLD
                     NDSHDIDSVGKNNMWIKGGKISFKMFQEALLDYTVSVSLFEPNFEQKSYIKGLYIQSR
                     GGDRSFLTGDKLEKDRDFFLTFSPSMNCLIGGRGTGKSTLIDMLQFVLSQDCDKQSKL
                     EFLCNHANAFVLYVLEDAEYIIEVSLPDVLQENRDNILQYYGQNRENRYGYPYNYNSD
                     SIKEWTRSQYTKVYKVEGKFFKLVDKTRILEKMFDRRYSVNELVRTADGEKITEFISD
                     LMLKNKNLPRPNYGLRTQTLESFEAKLQELDKYRRVRKDSILKIIDDFNQTQVGKLRI
                     CYEQIDRWEVPDFESTLFKSNSTLNFSFENYRISKRDVADILYLVYQELGIKGFVNVI
                     "
BASE COUNT         9413 a         5553 c         6718 g         7515 t
ORIGIN      
        1 tgaagaatta agacgtattt taaacaataa aaatgaagca attattatct tgaataatta
       61 ctttaaaggt ggtgttggaa agtccaaatt atcgactatg attttgattt atatcaaata
      121 gaatctcaat aacggtgagc cacaagcaca acatggagca attacccgaa atcctaatca
      181 aatcatttca actggcgatg ccatgctggg tggctactca agaatattgg attcaacagg
      241 attctttgtc tatgatagct tcaaaacagg tgagaccctt agttttaact atcaaaatct
      301 tcaacatgca cgatttgatg gtaaaaagat tagtcgagtg acttacgata ttaccaacct
      361 tgtatcacct gctggaacca atgccgtgaa attggttgta ccaaacgatc ccacagaggg
      421 ctttattgcc tatcgaaatg acggaaacgg tgactggcga acagacaaga tggagtttcg
      481 tgtagttgct aagtatttct tggaagacgg ttcacaagtt accttctcca aagaaaagcc
      541 aggagtcttc acacattctt ccctcaatca taatgacatt ggtctagaat atgtcaaaga
      601 tacttctggg aaatttgtgc cgattaatgg ttctaccgtt caagtgacta atgaaggtct
      661 agcacgttct ttgggttcca accgtgcaag tgatttgaat ttacctgagg aatgggatac
      721 cacatcaagt cgttatgctt ataaaggagc aattgtctca acagttacat caggaaatac
      781 ctacacagtc acctttggcc aaggcgatat gccacagaat gttggattgt cttactggtt
      841 tgccttaaat accctaccag ttgcacgtac agtgacacct tatagtccca aacctcatgt
      901 agcggtggaa cttgaacccg ttccagaacc tattacggta acaccagatg tctttactcc
      961 taaaacattt acaccagaaa agcctgtaac cttcacgcca aagcctttgg atgaagtagt
     1021 gcagcctaat ctgaccttga ctaaggtaac cttacctgtc aaacctattc caaaagaact
     1081 tccaacgcca ccacaagtac caactgtcca ttatcatgcg taccgtttga cgacaactcc
     1141 agagattatg aaagaagtgg tcaatagtga ccaagctaat cttcatgaga aaactgtcgc
     1201 aaaagattca acggtgattt atcccttaac agttgatgcc ttatcgccca atcgtgccca
     1261 aacgactagt ctcatttttg aggactactt gcctgctggt tacctctttg ataaggaaac
     1321 aacacaaaaa gagaatggaa actatgtcct tagctttgat gagactaaga attttgtgac
     1381 cttaaccgca aaggataact tgttgcagga ggtaaataaa gatttaacca aggtttatca
     1441 actgaacgct ccaaaactct atggttctgt tcaaaatgat ggggcaacct attccaatag
     1501 ttacaaactc cttttgaaca agggcacaac caatgcttac acagtcactt caaatgttgt
     1561 aacggttcgt acaccaggtg atggggagac aaccacactc attacaccag ataaaaacaa
     1621 tgaaaatgcg gatggtgtcc tcattaatga catggtcgta gcctttggca caaccaacca
     1681 ctaccgattg atttgggatt tggaccagta taagggagat cgttctgcta aagagacaat
     1741 tgcacgaggc ttcttctttg tggacgatta cccagaggaa gtgcttgata tggtggaaaa
     1801 tggcacgggt gttacaaccc ttgatggtca gaaggtatca ggaataacgg ttaaaaacta
     1861 tgcttcccta aatgaagcac ctaaagacct tcaagataaa ttagctcgtg ctaagattac
     1921 accgacaggt gcctttcaag tctttttgcc ggatgacaac caagcctttt atgaccagta
     1981 tgttcaaact ggaatatctt tagctttact gaccaaaatg acagttaaag atagtctcta
     2041 tggtcagaca aagacctatg caaacaaggc ttatcaagtt gatttcggca atggctatga
     2101 aaccaaggaa gtgaccaaca cccttgtttc tccagaaccc aagaaacaaa acctcaataa
     2161 agacaaagta gacatcaatg ggaagcccat gctagtggga actcaaaatc actatactct
     2221 ctcatgggat ttggaccaat accgagggat taaagcagac aactctcagg tttcacaagg
     2281 tttttacttt gtggatgatt atccagaaga agttttattg ccggatgaag cagctattca
     2341 gtttgtcaca tctgatggca aaacagtttc aggaatcacg gtgaagtctt attctcaatt
     2401 atcagaagct cctaaatctt tacaaacagc cctttccaaa caaaaaattc agcctaaagg
     2461 agcttttcaa gttttcatgc ctgaggaccc acaagctttt tttgaatctt atgtgaccaa
     2521 gggggagaat attaccattg tcactccgat gacagttttg gaaaccatgc ttaattcagg
     2581 gaagtcttat gaaaacgtgg cctatcaggt ggattttggc caagcttatg aaaccaaaac
     2641 ggtgaccaat tttgtcccta aagtaactcc acataagtct aataccaacc aagaaggtat
     2701 ttcaattgat ggaaagactg ttcttccgaa tacggtcaat tattacaaaa ttgtcttgga
     2761 ttacagtcaa tacaaggaca tggtcgtgac ggatgatgtt cttgccaagg gattttacat
     2821 ggtagacgat tacccagaag aagcccttac cctaattcct gatggcattc aagttttgga
     2881 taaggatggc aatcgtgtat ctggtatctc tgtcagcacc tacgctagtt tgtcagaagc
     2941 tccgaaagtc gtccaagatg ccatggctaa acgtcagttt acacctaaag gagccattca
     3001 ggtccttagt agcgatgatc ccaaaacctt ttatgatacc tatgtgaaga ctggtcaaac
     3061 cttagttgtc acgcttccga tgacggtaaa aaatgagttg accaaaacag gtggtcagta
     3121 tgaaaataca gcctatcaga ttgattttgg cttggcctat gtcacggaag cagtagttaa
     3181 taatgttcca aaattagacc cacaaaaaga tgtggtaatc gacttgtctc ataaagatgc
     3241 cagccttgac gggaaagaag tggccttgca tcaaaccttt aactatcgct tggttggagc
     3301 attgattcca agcaatcgtg cgactgattt atttgaatat ggttttgaag ataactatga
     3361 tgaaaagcat gatgagtata atggtgttta tcgcagctat ctgatgaagg atgtcatcct
     3421 caaagacggt tctgtattaa aagaggggac agaagtcacg aaatatacct tgcaacaggt
     3481 ggatacagaa aatggcctag tgtcaatttc atttgataaa tccttcttag agactatctc
     3541 tgatgattca gcttttcagg cagatgttta cctgcagatg aaacggattg cgactggtca
     3601 ggtggagaat acctaccttc atacagtgaa tggctatgtc atcagctcaa atacagttgt
     3661 aacatataca cctcaacctg aacaaccaag tccaaatcaa cccacaccac ctcaaccacc
     3721 aattgagact attgaagcgc ctgtttcagc aagcattttg ccaaatacag gggaacagga
     3781 atcccttttg ggcttgattg gagctggtat tctacttggt acggcttatg gactgaagaa
     3841 aaaggaggag aagtagatga atccaaaaag catttatgaa aaggattcag accaggatgg
     3901 tctgacagat gctcaggaac tggctttcgg aaccaatccg cagtctgttg acacagatgg
     3961 tgatggtcaa gctgatttag aagagctaca atctggacat tcaccattag tcccacaaaa
     4021 ggagttgtgt gatggcttgg aactttgaca ccatgaaaga ggctttgtct gaaatggaga
     4081 aggtcgatta ccaagagttt atcaaagcct ttctctcttt ggaattaagt atttctgata
     4141 gaacaatcct caatcaggtt tatcaagatt acatggatga ggatgaccta tccttgatta
     4201 gtgatgagct acgagttaaa gttgatagtt atcaggatga agtacaggca gatatgactg
     4261 acattctaga aaagttgtac cgaacaggtg aaggctctag ttttattatg gatttaatgt
     4321 cctcaaatag tctctcagac accttggaac agtatgaggt tttggatagt gacgattatt
     4381 caccacttag ccttgaaacc ttacaggcca tgatccaaca ggacttagct atttccagtc
     4441 aggattattt tggagatctg gttcaccttg ccttgcaaaa agatttacta gaccagaaaa
     4501 gtcatttctt acaacactat gtggcaactg taatggaagg tattccacaa gaaagagacc
     4561 aacgagcctt ggtcctagat taacgcaaag ggctgagaaa aactctcagc ccttttaaaa
     4621 tgggagggaa aatgaatcaa gaagtcttac tacaaatgat gagagccacc attcctcgtg
     4681 atagagccct gcttgaggca tttttatatt accaagcaga gcattttgat gaggagtggg
     4741 atagtcttat tcgtcagttt ttatccaata ggcaagcaaa catcagccct gttcaggtac
     4801 ttcactttga gacagatgtt tcagcttttg tccaggctag tccttatgat aatgctcatg
     4861 atctattgac ctatacacaa gtattcggcc aaactggtct ccaaaaactc gacaaactat
     4921 cgccgtctga aaaagacttg gtgattgaag tggccttgtt caatctggcc actcgttttc
     4981 aactattaga ctcaaatgga cactaccaaa ctatttcacc agattctctc ttacaaaaga
     5041 gtaggggagc taatttggtc aatgtttatc gtgtggctaa taatttagcg gatcgaatca
     5101 gccgagatat tgaacagttt ctcttgactt acgagcctga gcttgaaaca agagctgata
     5161 aaactgttct agaaaatgaa gaaactggtg atgagcacaa agtgagtagt aatcaagcaa
     5221 taccatttag agaagatggc tctctcatca ttgctagttt ggatgtagat ttgtctcaac
     5281 tgaatgttca aacaggaaaa accagtcatc tgccagctta tgaagagttg ttattacaac
     5341 gtaaatttga gattctaaca tattttgacc atattcgaaa tgaacgttcc aaagtcccaa
     5401 gttttaaacg aggtgatttt gatactgaga tggaaatgac accaatcttt gagggcaagg
     5461 agttacttac ctatctagaa gctgatggca gtccctatga gctgaaacga acgctgacta
     5521 cagtcgaaga aaaggaatta gaaaaaattg gacaagccat taggatagaa aatcaagaaa
     5581 aattgactca gctagggatt gagctatctc agtttgaccc agaccgagtc ggtattttat
     5641 tggatgcggc aggtcgttat cgtttaaaaa atgcggacct tgctttacta ggtggttatc
     5701 ccaaagcctc ggtaactcaa ctagcccttg cgacagaact actccaaatg ggactaagtc
     5761 atgaaaaggt tgaatttttc tttggtagcc agctttccct tgaagagttg cgacaagttg
     5821 cttacgcctt tttacacgaa gaactcagca gagaagatgc ggagcaattt gaaaaagata
     5881 aaggtaatca gccagattta accctcagag attggaagag caagctagag aaagctgaga
     5941 gaaaagaagt agttgatgaa gaatttgtgg aaaatccact agtccagaga gtattggaca
     6001 cttatcctct ggggtcattg gtttcctata agggacagga ctttgaggtc gtgtcggtca
     6061 gtgatgctcg attgaacggt ttgattcgga ttgagttagt caatgacttt tcggatatca
     6121 ttgaacaaaa tccagttctt tatgtgagga cctgggaaga agtcagtcag gcacttcatc
     6181 agccaaaggc agaaccacaa acagagttag aagaagcgga ccaagaacta aatctttttt
     6241 catttctgga agaggagcca gttcagagta ttggactatt ggaaccagat ggttcagaaa
     6301 aaggtcataa cgatactgat cttgaagaaa cagataatca aattcctgaa gaggaagtcg
     6361 tcgaaacaat tccagagatt ccagtaacgg acttttattt tccagaagat atgacggact
     6421 tttatcctaa gactgctaga gataaggttg agacaaacat tgcggccatt cgtttggtta
     6481 aaacacttga aacgggacgc cgtcaggcaa gtacaagtga acaagaactc cttgccaagt
     6541 atgtgggctg gggtggacta gccaatgatt tctttgatga ctataatcca aaattttcta
     6601 aggaacgaga agaactgaaa agcatagtca cagataaaga gtattcggat atgaaacagt
     6661 cctctctgac agcctattac acagacccag ccctgatccg tcagatgtgg gataagttgg
     6721 aaagagatgg ctttacaggt ggcaaaatcc tagatccttc catgggaaca gggaattttt
     6781 ttgcagcaat gcccaaacac ttaagagaaa agagtgagtt atatggtgta gagttagaca
     6841 ccatcacagg agctatagcc aaacaccttc atcccaatag tcacattgaa attaagggct
     6901 ttgagacggt agcttttaac gacaatagtt ttgatttggt gatttcaaat gtgccgtttg
     6961 ccaatatacg aattgcggat aacaggtacg ataagcctta catgattcat gactactttg
     7021 tcaaaaagtc acttgatttg gtccatgatg gtggacaagt agcgattatc tcttccacag
     7081 gaactatgga taagcgaaca gaaaatattt tacaagatat tcgtgagaca actgaatttc
     7141 ttggtggggt tcgactgcct gattctgcct ttaaggccat tgcgggaacg agtgtcacaa
     7201 cggatatgtt attcttccag aaacacctga acaaggaata tgtggcagac gactcagcct
     7261 tttcaggttc cattcgctat gacaaggata gtcgcatttg gctcaatctt tactttgatg
     7321 gagaatacaa tagccaagtg ctaggaacct acgaggtcag gaattttaac ggaggaacac
     7381 tttctgttaa ggggactagt gatgacttga ttgcaagtgt tgaagcagct ctacatcaag
     7441 taaaagcccc aagagagatt gatagaaatg aggtcatcat taatccagat gtgttgatca
     7501 aacaagtcat tgatacctcc attccagctg aaatgaggga gaatctgggt cagtacagtt
     7561 ttggttacca gggttctaca gtttactatc gagataataa aggcattcga gtcggaacca
     7621 agacggaaga aatcagttac tatgtcgatg aagagggcaa cttcaaagca tgggacacca
     7681 aacattctca aaagcagatt gatcgcttta atgccttaga agtgactgat aacactgctc
     7741 tggatgtcta tgtgacagat gatgcagcca aacgtggtca gtttaaggga tattataaaa
     7801 agacagtttt ctatgaagct cctttgtctg ataaagaagt ggcacgaatc aaaggaatgg
     7861 tcgatattcg caatgcttac caagaagtca ttgccattca acgctattat gactatgata
     7921 agaagacctt taaccacttg ttaggtaaac tcaatcgtag ctatgatagc tttgtcaaac
     7981 gctatgggta tttgaatagt gctgtgaacc gcaatctttt tgatagtgat gacaagtatt
     8041 cgcttcttgc tagtttggaa gatgaaagtc cggttccaag tggaaactcc gttatctaca
     8101 ccaagtccct tgcttttgaa aaggctctgg tgcgtcctaa aaaagaggtt aaaaaggtac
     8161 atactgccct tgatgcctta aattcgagct tggctgatgg tcgaggtgtt gatttcgatt
     8221 atatgatgtc tatctatcag gttgaatcga agatgaactt gattgaggag ttaggtgacc
     8281 tcattatgcc tgatcctgag aagtatttga atggggagct gacctatgtt tctcgcctag
     8341 actttctgtc aggtgatgtc gttaccaagt tagaagtggt ggacctattt gtcaaacaag
     8401 acaatcagga ctttaactgg tcacattatg cgggacttct agaagctatc aaaccagccc
     8461 gtattacttt ggcagacatt gattatcgaa tcggttcacg ctggattcct ttgtctgttt
     8521 atggaaaatt tgcccaagaa acctttatgg ggaatgccta tgaattatcg gaccaagaag
     8581 tagcgacagt cctagaagtc agtcccattg acggggttat cacttaccaa tctaagtttg
     8641 cctacaccta ttccaacgca atggatagga gtttaggtgt ccctgcttca cgctatgata
     8701 gtggtcgaaa aatcttcgaa aatctcctga attccaatca accaacgatc acaaaacaaa
     8761 ttgttgaagg ggataagaaa aagaatgtga cggatgtaga gaaaacaacg gtcctgcgtg
     8821 ccaaggaaac acacctacag gaattctttc aagattttgt agcaaggtat ccagaagtcc
     8881 aacagatgat tgaagacacc tataacagtc tctataatcg tacagtatca aagacctatg
     8941 atggtagtca tttaaccatt gatggacttg cccagaatat ctccttacgt cctcaccaaa
     9001 agaatgccat tcaacgaatt gtggaggaaa aacgtgccct actagcccac gaggtagggt
     9061 caggaaaaac cttgaccatg cttggagctg gtttcaagtt gaaagaatta gggatggtgc
     9121 ataaacctct ctatgtggtt ccttctagtt tgactgccca gtttggtcaa gaaatcatga
     9181 aatttttccc taccaagaaa gtctatgtga ctactaagaa agactttgcc aaagccaaac
     9241 gtaagcagtt tgtgtctcgg attattacag gggactatga tgccattgtc attggggatt
     9301 cccagtttga gaaaataccg atgagtcgtg aaaaacaggt cacctatatc aatgacaaac
     9361 ttgagcaact cagagaaatt aaactaggaa gtgactctga ttacacggtg aaagaagcgg
     9421 aacgttcgat taagggattg gaacaccagt tggaagaact ccaaaaacta gagcgagata
     9481 cctttattga atttgaaaat cttggaattg attttctttt tgtggatgag gctcatcact
     9541 tcaagaatat ccgtccaatc actggacttg ggaatgtcgc gggaatcacc aatactactt
     9601 caaaaaagaa cgtagacatg gagatgaagg tgagacaggt tcaggcagaa catggagata
     9661 gaaatgtcgt ttttgcgaca ggaacgccag tttctaactc tattagtgaa cttttcacca
     9721 tgatgaatta cattcaacct gatgttttag agcgatacca ggtatccaat tttgattcat
     9781 gggttggggc ttttgggaat attgaaaact ccatggaact agccccgaca ggtgataaat
     9841 accaacctaa gaaacggttt aagaaatttg tcaacttgcc tgaactcatg cgaatctata
     9901 aggaaactgc cgatattcag acctcagata tgctcgactt acctgtacct gaagctaaga
     9961 ttattgcggt ggaaagcgag ttaacgcaag ctcagaaata ctatttagaa gagctggtag
    10021 agcgttcaga cgctatcaag tcaggtagtg ttgctccaag tagagataac atgcttaaga
    10081 taactggaga agccagaaaa ctagccattg acatgcgtct cattgatcct gcttacacct
    10141 tgtctgacaa tcagaagatt cttcaagtag tggacaatgt ggaacgcatt taccgtgagg
    10201 gagaaaatga gaaagctacc cagatgattt tctcagatat tggaacgcct aagagtaagg
    10261 aagaaggctt tgatgtttac aatgaattga aagacctttt agtggataga gggattccca
    10321 aagaagcaat agcctttgtc catgacgcta atacggatga caagaaaaac tctctgtcac
    10381 gcaaggtcaa tagtggagaa gtacggattc tcatggcttc gacagaaaaa gggggaacag
    10441 gattaaacgt ccagtctcgc atgaaagctg tccaccattt agacgttccc tggaggccct
    10501 cagatgtagg acggattttg cggacattca aaataaaaaa gaatgtggag gtaacagaca
    10561 atggcaaaga caatttttga ggaaatgggc ggcaaatacg aaaggcaagg cgattattta
    10621 ataccgtgct taactgtacc cgccgaagaa gaacagccga taggcatctg gggacagcgg
    10681 catttggatt atctgaagca tcactgcaaa gttacataca ccaatcttct tacaagcggc
    10741 agacttaacg cttaccttgc cgacattgac agacaggcac aggaacgctt tgaaaggctc
    10801 atagagggta tgaaacaggc acagggcata acggaacagc taaaggcaga aaacgcctta
    10861 gaatggacag gatgcctcaa taacataagg gcttgtgcga gggagattgt ggaaaaggaa
    10921 attatttttg cataaacaga tgattagtgg cagggggaaa tcctgccgct ttttctgctt
    10981 tagtttgtca gcttgacaaa taaagggtta aggaatataa ttagattcag tattatacaa
    11041 ggagttaata aatatgcggc aaggtattct taaataaact gtcaatttga tagtgggaac
    11101 aaaaagtagc agtcccgttt cacttttaat atggggctta gttttttgta cccagtttaa
    11161 gaatactttt atcatgtaat tttatatgcc cgaaaacata taagtgtttt ggggctattg
    11221 gagttattta cccagtgata ggagtattta tcactgggta tttttatgcc cttttttggg
    11281 tgttgatagg aggaaaatca catgaaaata attaacttag gcattctggc tcacgttgac
    11341 gcaggaaaga caacattaac ggagagttta ttgtatacca gtggtgcaat tgcagaacca
    11401 gggagcgtag ataaaggcac aacaaggaca gatacaatga atttggagcg tcaaagggga
    11461 atcactatcc agacagcagt gacatctttt cagtgggagg atgtaaaagt caacattata
    11521 gatacgccag gccatatgga ttttttggcg gaagtatacc gttctttatc cgtattagac
    11581 ggagcagtat tattagtttc tgcaaaggat ggcatacagg cacagacccg tatactgttt
    11641 catgcactac agacaatgaa gattccgaca atttttttca tcaataaaat tgaccaagag
    11701 gggattgatt tgccaatggt atatcaagaa atgaaagcaa agctttcttc ggaaattata
    11761 gtgaagcaaa aggttgggca gcatccccat ataaatgtaa cggacaatga cgatatggaa
    11821 cagtgggatg cggtaattat gggaaacgat gaactattag agaaatatat gtcagggaaa
    11881 ccgtttaaaa tgtcagaact ggaacaggaa gaaaacagga gattccaaaa cggaacgtta
    11941 tttcccgttt atcacggaag tgctaaaaac aatctgggga ttcggcagct tatagaagtg
    12001 attgccagta agttttattc atcaacgcct gaaggtcaat ctgaactatg cgggcaggtt
    12061 tttaagattg aatattcaga gaaaaggcgg cgttttgttt atgtgcgtat atatagcgga
    12121 acattgcatt tgagggatgt tattaaaata tctgaaaaag agaaaataaa aatcacagag
    12181 atgtgtgttc cgacaaacgg tgaattatat tcatccgata cagcctgctc tggtgatatt
    12241 gtaattttac caaatgatgt tttgcagcta aacagtattt tggggaacga aatgctgttg
    12301 ccgcagagaa aatttattga aaatcctctc cctatgctcc aaacaacgat tgcagtaaag
    12361 aaatctgaac agcgggaaat attgcttggg gcacttacag aaatttcaga tggcgaccct
    12421 cttttaaaat attatgtgga tactacaacg catgagatta tactttcttt tttggggaat
    12481 gtgcagatgg aagtcatttg tgccatcctt gaggaaaaat accatgtgga ggcagaaata
    12541 aaagagccta ctgttatata tatggaaaga ccgcttagaa aagcagaata taccatccac
    12601 atagaagtcc cgccaaatcc tttctgggct tctgtcgggt tgtccataga gccgctccct
    12661 attggaagcg gagtgcagta tgaaagcaga gtttcacttg gatatttaaa ccaatcgttc
    12721 caaaatgcgg ttatggaggg ggttctttat ggctgcgagc aggggctgta tggatggaaa
    12781 gtgacagact gtaaaatctg ttttgaatat ggattgtatt atagtcctgt aagtaccccc
    12841 gcagactttc ggctgctttc ccctatcgta ttggagcagg ctttaaaaaa agcagggaca
    12901 gaactattag agccatatct ccactttgaa atttatgcac cgcaggaata tctctcacgg
    12961 gcgtatcatg atgccccaag gtattgtgca gatattgtaa gtactcaggt aaagaatgac
    13021 gaggtcattc tgaaaggaga aatccctgcc agatgtattc aagaatacag gaacgattta
    13081 acttatttca caaatgggca gggagtctgc ttgacagagt taaaaggata ccagccagct
    13141 attggtaaat ttatttgcca accccgccgc ccgaatagcc gtatagataa ggttcggcat
    13201 atgttccaca agttagctta acagcttgca aaagtcatat aaaatgagat ttgaaaggat
    13261 tagagactaa ttatgatgaa atgcgaatgg atattgtgtc ctgtttgtgg gagcaaaacc
    13321 cataataaaa ttaggaagga cactgttttg gagaattatc ccctttattg tccaaaatgc
    13381 agacaagaaa gcttgattaa agttgacaac ttgaagataa ctgtcatcaa agagccagac
    13441 gcttaagacg catagccgat gaaattgtgg aacaattcac gaatcatcgg ctctttttgt
    13501 ttcgtatttg aaagaacaaa ctcaccaaat aaaaaaaacg atattcgggt gggttatttt
    13561 gttataccct aaattaccct ctgaatttgt ttttaaattt ggagggattt ttttatgttc
    13621 ttttttcggg cggttattca tctgctcata cgaagtaaaa tttatcaata catagcatat
    13681 cagagaatgg caggaaacca gttaaaaaaa tttctgccag tgcagcggta cttctcacct
    13741 tgaaagtgga agtacaatct ccatacaaca gaatttgtat ttcccataac cgtgaaggtc
    13801 acagagcctt tgcggttttt cttttgtcgt tttttgttgg aaagtgccgc agggctgttt
    13861 ctggtgtgcg ttgccgctcc ccgcctctcc atctggattt ttacatttca aaaattcaga
    13921 ttggaggtat tagcggtgaa atacgcacca agaaaagtat atatcaaaga aagcggcggc
    13981 tatgtggaac tgtcctatac ggatttctgc cgccgcaggc aagccgacaa gggatatatg
    14041 gacaagctgt ttatccccgt ccaaggttgt ctgcttgaag tcgtaaggga gcaatatgcg
    14101 gacttctacc gtgacaggga gcggtggcgt tacctgcaaa aattagatgc gaggaacagc
    14161 ctgctatctc tggacggatt tacggacagc gaggggaatc ctctggactt tatcgctgat
    14221 gaagcggcgg acattgcgga aaccgttgtc aatgctgtta tggtggacag gctgaaagcc
    14281 gccctgcctt tgttgtcgga tagtgagcag gagttgatac aggcaatctt ttttgacgga
    14341 ctttccgagc gtgaagtcgg ggcgaggtta ggcataaccc agagcgttgt gaacaaacgc
    14401 aaagccagaa tcctaagaaa actaagaaag ataatagaaa attaaaattt aaggcgttca
    14461 gcccccttgt tttttccttt gggaaaatga gggggctttt ctctgccctc tcaatcaatt
    14521 ctgattggag gaagaaagaa tggcatacaa ccacggacgg gaggacagga aatggcgtat
    14581 ctggaaagaa gcggaggaaa agctgctgcg tgagtgcggc gttgatgaag tgaccattga
    14641 gcagatacgc atagcggaca gggcagactt caattccaac aggcggtttt accgatggac
    14701 gaatgacgtt gcggaatacc ttgaggacat ggcagacagg gagcggcaag cggaggtgaa
    14761 tacagttgcg gagttactgg acgagattga gagcgaaaat ctctatcaag tattagtcac
    14821 ggtggacggg cgtaccttga aaatcgtcct gctgaaaatg caggggtatt ccacaaagga
    14881 gattgcccca cttgtgcatt tgacgactgg tgccatctat gcgaggttag accatctgcg
    14941 gaagaagctt cggaaaattt tgtaagcgtc taatacatcc cattattctg cgggctactg
    15001 ggtggggagt ggaatctccc cgcttatttt tggcaggagg aaaacgggat ggcatataaa
    15061 gctaaggcgt acacgcttcg ggaggaatcc acggaaagcg gtataaggta ttttatcagt
    15121 tttaaggacg ggcaggggga acaccacgaa ctggaagtat ccgagcagtt attctttgaa
    15181 tttcggcaga tggaacgcag gaacaggaat cttctccaat gggacgagcg gcacagggag
    15241 ttttcggaag tatgggacga aacgctgaac aggcgggcgt taaagctgcc taagagcatt
    15301 gaggaacaaa tgattgaagc agaacgggcg gaactgctct gtaaggcggt tgacagactg
    15361 ccagagatac aaaggcgacg tttcctgctc tactacgagt atgagttcaa tttttaccaa
    15421 atcgccgcta tggagcattg caccgcttct gcaatacaga aatccgttgc tgttgcaaag
    15481 aagaaagtaa aagcggaaat gaggaaatat ctccaaccat gaccgacacc gcccgaaaaa
    15541 gaaatctgtt ttttatttgt gtgggattgg cggtattaca tactctcact tttttcgtgg
    15601 gagtaaatct atttttaagg aggtcaacgc ctatgtgcaa caaaaacaag ataactgccc
    15661 gaaaggagga aacccatgca gaagttacag acagtcaacg ccgaaacgct cctttatgag
    15721 ccgcttgaga agccgtcctt tgtggtggac agccttatcc ccacaggctt gtcgctgttc
    15781 tgcggctcac agaagatagg caagagctgg ctcatgctga agctgtgctt atgcgtgtcg
    15841 cagggaatcc ccttatggga catgacgaca atggagggcg atgtgcttta cctctgcctt
    15901 gaggacacgt tctgccgcat acaggacagg ctgttccgtt tgacggacga agcgagcggg
    15961 cggcttcatt ttgccgtggc aagctgcaag ctgtcagacg gtcttatcgt gcagcttgag
    16021 gattatctga aagactatcc agacagcagg ctcattgtca ttgatacctt gcagaaagtc
    16081 cgtacagctt caaaagacaa cgcctatgca agcgactatg gggacatctc cctaatcaaa
    16141 gattttgccg acaggcactc tctggcggtc attgtcgtac accacatccg aaagcagaat
    16201 gacagcgatg tgttcaacaa ggtgtctggg acgacaggct taacggggag tgcggacgct
    16261 acctttgttc tggaaaagga gaaacgggca tctgacaccg ccaagctgta tgtaacgggc
    16321 agggacacgc cctatcagga atacacgctc cgtttccgtg attgcagttg ggaacttgtg
    16381 gagaggaaaa cgcaggagca gcttgcgaaa gaaacgatac cagatgtcct ttttcggttg
    16441 gtggatttta tgagggataa ggaagaatgg gcaggcacgg caacggagct gttagccgct
    16501 atgggggaaa cggaaaccat acccacggtg attacgaaat ggctgaatga atatcacacc
    16561 acatttttaa gcgagaaccg tatctgctac cagtacagcc gcaggaaaga cggcaggcag
    16621 attgcccttg caaggagggc gggtgacagc ggtgacggcg gtgacagcga tattgggata
    16681 ccccctgtta ctgtcattga cgcttaaagc catgtaaagt tggcggctct gccctgcggg
    16741 tgacagcggt gacggcagtg acagtgattt taggataccc tgccgctgtc atccctacgg
    16801 gagaacaccc cgcaaacgca aaatgcaggc gtgggattca cccgcccttt tcgggcgtgt
    16861 aaaatcaccc ctgcggtcag aaaaatctct ccgatttttc cgactgcgtt tacagggtgt
    16921 aacacactac actttgccct gcaaagagcc gtgtgccaga cgttccctct ggactccctt
    16981 atggcaggtc ttacgccctg ctatcctacg ccttgcggct tcggataaaa gaacggcggc
    17041 atgacggtta cagctcttgc gagggagtat cccaaaaaca ccgtcaccat cgtcatgacc
    17101 gtcatgcagg ggataagggt gacagttacg gcaatcggca gggggcatcc caaaactgcc
    17161 gtcaccaccg tcaccgctgt cacccaaagg gcagttaccc gccgaagaaa ggaagatgat
    17221 ggattatgcc ctatgcaatc ctgcgtttcc agaaacgcaa agcgggcggc gttgcggctt
    17281 gcgaacgcca caacgagcgg aagaaagaag cctacaaaag caacccagat atcgacatgg
    17341 aacgctctaa aaataactat catcttgtcg caccgccaaa gtacacctat aagaaagaaa
    17401 ttaaccgaaa ggtagccgaa gcagggtgca ggacaaggaa agacagcgtg atgatggtgg
    17461 aaacgctcat cacggcttca ccagaattta tgaaccagtt accgcccgaa gaacagaaag
    17521 cgtattttac gatggctctg gatttcattt cggagcgtgt cggggagcag aatatcctct
    17581 ccgcagtcgt ccacatggac gagagaacgc cccatatgca cctctgcttt gtgccgatta
    17641 caccagacaa taagctgtcc gccaaaacaa ttttaggcaa tcaaaagagc ctgtcggagt
    17701 ggcagaccgc ctaccatgag cggatgtcct cacgttggaa tcagcttgag agaggtcaat
    17761 cttcgatgga aaccaagcgg aaacacgtcc ccacatggct ctataagttg ggcggcaggc
    17821 ttgataagca gtatggggaa atcgtgtctg ccctgtccga catcaacgcc tttaacgcag
    17881 ggaaaaagcg tgacaaggct ctggaactgg ttgccgcatg gctgcccgaa gtggagaaat
    17941 tctctaagga aatcggcaga cagcaggcgt atatcgacag cttaaaggag caaatcgggc
    18001 aggaagccga ctatgcaggg cgtatgcgtg atgaaaagta cgagcaggaa ttaaaggtgc
    18061 agaaagccaa ccagaggata tttgaattgc agagaaccaa cgagcagatg gggcggctgc
    18121 tctcaaagat accgccagaa gtgttggaag aattacagag aacaggcaga aacaaatcaa
    18181 gagaaaggta aaaagtgaat gaagaaacag gattttaagg tgttaaagac caaagattta
    18241 tacccgtttc ccgacaatcc gtttcatgtt gtggaggatg aaacgctgtc agagttagcg
    18301 gaaagcatca aggaatttgg cattgtcacg ccgataatca cacgcccgaa agaggacggg
    18361 aacggttatg aagtgattgc ggggcagcgg cgtgtccgtg cgtccgaact tgcaggtata
    18421 aataccgtgc ctgcatttgt cctgccctta gaccgtgacc gagccatcat cacccttgta
    18481 gacagtaatt tacagcgtga aaatatcctg ccatcggagc gggcgtttgc ctacaggatg
    18541 aaatccgaag ccatgaagcg gcagggtttc cgcacagact taacctcgtc acaagttgtg
    18601 acgaagttgc ggacggacga caaagtggca cagggcttcg gcgtgggcag gatgaccgtc
    18661 cagcgtttta tccgcctgac ggaactgata ccgccgattt tgcagatggt ggacgagggg
    18721 aaaatcgccc tcacacctgc ggtggaactg tcctttttga agaaagacga gcaggaaaat
    18781 ctctttgcca cgatggagag cgaagaagca acgccctcac tctcacaggc acagcggatg
    18841 aaaagcatga gccagagcgg gcagcttgac atggatatga tattttccat tatgacggag
    18901 gaaaagggaa accagaaaga aaccttgaaa atcaacacaa gcaaactgaa aaaatacttt
    18961 ccgaaggaca caacgccgaa gcagatggag gaaaccatca tccgacttct ggaacgtgag
    19021 ttgcagagaa aacggagcag ggacagccgc taaccttctt ttttcgggaa gtaaatgcag
    19081 gaatttggaa cagaagaaag acagaatttt aaggagaatg aggtaaggaa tgaaagaaat
    19141 ccagtatgag attgtaaagg aaatcgccgt attgtctgcg agtgacagcg gctacacaaa
    19201 ggaaatcaat cttatttcat ggaacgggag agagccgaaa tatgacatcc gcagcttttc
    19261 cccgaaccgt gagaagtgcg gaaagggtat cacgttgaac gctgatgaag cagcggcact
    19321 ccttgaagca ttacagaaag aagtaaacag cggggattga tggtatctga ttgacagggc
    19381 ggggcgtttc cagacgttct cctgccctgt ctggaaagga agatttaagt atgggcgagg
    19441 ataggaaaac aactggaaga agaaagcgta ttgtgccaaa agggcaagta caaatgatta
    19501 tcagtcgaga atatatcggc acacagaccg ttgcagaagc gtttgtcccg attatctccg
    19561 aggatattcg gaagaagatt gccgagggcg acaccttcga caatgagggg ctgtccgctt
    19621 agaatgtacg caatggaaca tgaaaacgtt aggacagata tggaggtttt acagtatggc
    19681 aggaataaga acggagaaca agatttatga agtcggcatt tactgccgct tatcaaagga
    19741 cgatggcacg gataacgaga gtgcgagcat tgcgacacaa aaatccatcc tcacggatta
    19801 tgtgaaaagg cagggatggc atttagcaaa aacgtatgtt gacgatggct actctggaac
    19861 aaatttccaa agaccaagtt tccagaatat gattaaggac attgaaaacg ggctgataaa
    19921 ctgcgtgatt acaaaagatt tatcccgtct ggggaggaac tatcttgatt gtgggttata
    19981 tctggaagtc tttttcccag agcataacgt gaggtatata gcggtcaatg acggcgtgga
    20041 caccttaaac aaatccgcta tggacatcac gcctttccgc aacatcctaa acgaaatgta
    20101 ttctgccgat gtgtcagtca agataaaatc ggcgtaccgt gcgaggtttc agcaggggaa
    20161 attcatggga acaacagccc cttatggcta tgtcaaagac cctgccgacc acaaccatct
    20221 gctgatagat gacaaagttg cccatgtggt aagggagata ttcgaccttg cgttagcggg
    20281 caacggcatc gccaaaatcc gcaagcacat caacaaacag catatcctac gccctgccgc
    20341 ttatgcggtg gagcaagggg caacaggcta tgagcggtac tttgaggata acgaggaaaa
    20401 ccgttatatt tggagcgaga acagcgtgag gggcatttta agaagcccga tatatgcggg
    20461 caaccttgca ggctacaagc ggattgcagc caacatgaaa agcaagaaac gcccctctaa
    20521 gctgcccgaa gaatgggaag tgataccaga cacccatgag gggatagtca cgcaggagga
    20581 atttgacacc gtacagcagc ttatgacgag ccgcaggcgg gagcagaacg cagggggatt
    20641 tgagaatatc ttttcgggcg ttatcaagtg tgcggactgc ggctatgcga tgcgggcggc
    20701 gagtgccaac aggaggaaac gccccgacat catcgactgc gtacaataca cctgcaataa
    20761 ttatggcaga tatggcaatg ttatgtgtac cgcacacagc attgaagcga gggacttatt
    20821 caatgccgtc cttgccgaca tcaaccgctt tgcggatatg gcggtcaatg atgaaaaggc
    20881 ggtcagagcc atagaaaggc ggctcacgga aacagaccag agcagggcga aatcattaga
    20941 gaaagaaaag aagaagctga acaaacgcct tgcggagctt gacaggctgt tttcctctct
    21001 ctatgaggac aaggtaatgg agcgtatcac ggagcggaat tttgagatga tgtcggggaa
    21061 ataccagaaa gagcagcttg aaattgaagc acggctgaaa gaggtaacgg aaacgctcaa
    21121 tgacagctat gagaaatcgc agggcgtgag ggactttcta tccctaatcc gcaactatca
    21181 ggggctgaaa gagttggacg caaccatcat aaacgcactc atagacaaga tacttgtttc
    21241 ggaacgtgag aaacttgcgg acgggacagt aaggcaggaa atcaagattt actataaatt
    21301 catcggcttt gtcggtgaat tacatatcac acccacaaag cggtggacgg cgttaaagcc
    21361 taaaaattgt acggtgtgcg gtgttgaata cgtccccagc tctggaatat caaagtattg
    21421 tcccgcttgt gctaagagga tacagaggga gaaatcaaac gagagcaaac gcaggagtag
    21481 ggagaggaac cgaagggcat gtattgaact gtccgcaaaa aatgaccgac tgacattgtc
    21541 cagcgaaatg gacgactaat tcgacaagga aacatgcacc aggaggtaga tatttatcac
    21601 tatattacta aagggagctt cgacaattac ctatggcaga cacaggagaa taagctaaag
    21661 tatatcaccc agataatgac ctcaaaagat cctgtgagat cagctgaaga cattgatgaa
    21721 caaaccatga ctgcctcaga ctttaaggcc ttggcaactg ggaaccctta tctcaaactc
    21781 aaaatggagt tggaaaatga actgacagtt ttagagaatc aaaaacgagc ctttaatcgc
    21841 tccaaagacg agtatcgcca taccatttcc tatagcgaga agcacctccc tatcatggaa
    21901 aaacggttga gtcaatatga taaagatatt gcccaatctt tggcaacaaa gtcgcaagat
    21961 tttgtcatgc gatttgacaa tcaagcaatg gataatcgtg ctgaagctgg ggactatctg
    22021 cgaaaactca ttacctataa ccgctcagag accaaggaag ttaaaacact tgccaacttt
    22081 agaggatttg atttgaaaat gacaacacga gctcctagtg agcccatgcc agagactgtc
    22141 tctttaatga ttgtaggaga taaccagtat actgtcgccc ttgatttgaa atcagacgtg
    22201 ggaaccattc aacggattag caatgccatt gaccatatta tagatgacca agaaaagacg
    22261 cacgagctgg taaaggattt aaaagataag ctacgagtag ccaaagtaga agttgaaaaa
    22321 gcctttccaa aggaagagga ctatcagctt gtaaaggcta agtatgatgt tttagctccc
    22381 ttggttgaaa aagaagcaga gattgaggag atagatgcag ctttggccaa gtttagtgaa
    22441 gatacaacac cccaaaagaa gcaacaaata gcacttgaga tataagaaaa aaggctgaca
    22501 aataattttg aacgcggtaa aatgaagtta agaaatcaca taaggagaat agatcatggg
    22561 ccaaacagta gaagaaatgc gttatcaact agaagaatgg ttgtcacaag gctttacgag
    22621 ttcagaagat agggcaaact accaaacttt aaaggaacag tatgaagatg agacctttga
    22681 ttacagtttt tcaaggcgtg aaattactgg acagctggaa atcatcatca caagtcgtga
    22741 gaatgatttt ccaagcttag ataaggtgac gaaggcagaa taccttgatt tggttgccca
    22801 acttgatgat ttagacaaga gacaggctga ctattatcgc aagcaattag cctagaaaga
    22861 ggtgtaagat gttggagcaa attctacaaa gccttttgat tatcgcagca ataggactga
    22921 tgttgtttgt cctttatcgg attgtgaaag tttcaggtgc tttatttctt atcggactca
    22981 tcagtggatt agtctttatt gaaatatatg gaatttacct attcttcaca gaaagacacc
    23041 tatattcaga agatttagca gctaatggca tatggagttt cactggattt tatattgcat
    23101 tgaatttatt tcttgctatt agcttaagta tgaggtggtg gagaaataga atcgtttaac
    23161 atggggatta cctactggta gtcctttttc ttgtgataaa atctccaagc taatcttgat
    23221 atgatgaagc tatcactaat agaggagtaa gccatgttaa ataaagtgaa agctcgattt
    23281 ctgattggat taggaggttt aatcgcagtc agttttatgg tcatgattgg ctacacgatt
    23341 ggctcacaaa ccatttcaaa gcaaacagag aaccaaatac gagcagaagc caataaactt
    23401 gtgtcaaaga aaaagcagga ggaaagagcg acagtcctat cagatgagct tgtcaatgaa
    23461 tttctcactc aatatttcac caaggtccag ctgggtgaaa ataacgctcg tatcaaaccc
    23521 tacatgacgg actcggcatt ttcagaagag gaagcaaatc agaataaagc gatcaatcaa
    23581 gtttataaag actatatgct tgactaccga tttgaatcag ccagtatcta tgtcaataca
    23641 gaaagtaatg ttgcacttgc ggaagttacc tatcaagtga cctatgtatc tgatttgagt
    23701 gagcaacaac agcgaacctc tcaaacagaa accaagacgg ttatgttatc ctactccaaa
    23761 gtttccgaca agctcctggt taatcagttg accatttgga atggaaaact agaggacatg
    23821 aaagaagcca cagatggtgc aaattccagc ataccaacga tccaaggaac tacgacaagc
    23881 gagaacaact agcaggagac agtcttctgc tttttttgat agggagacaa aatgacacga
    23941 attaaagcag taaaacaaaa ggccatttta gatgtggctg aaagtctggg ttattccttc
    24001 agacgtttat caggacacat ttatgaacac ccagaccatg attcctttcg gatttttgcc
    24061 gataccaata ctttcaaatg gttttcaaga gatatacaag gggatgtaat tgactttgtt
    24121 caattagtag caggcgttac tttcaaagag gctgtatctt atcttgaaac tggagatttt
    24181 gaacaagcta agttgataga agaaacttat caaccatttc aatactattt gcatgaagaa
    24241 ccctttcagc aagcacgtac ttacttgcaa gtcgtccgtg gcctaagtga tcagactatt
    24301 aatacctttg gcagacaagg attgcttgct cacgctactt atcaatcgga gcccgtatta
    24361 gtgttaaaaa gctatgacca caacgggacc ttacaggccg caagccttca aggtctcgtc
    24421 aaaaatgaag aaaaacacga tcgaggttat ctcaaaaaaa tcatgaaagg atctcatggc
    24481 tatgtcggta ttagtttcga tattgggaat cctaagcgac tcattttttg tgaatcagtt
    24541 atcgatatga tgagttatta tcagctttac caaaagcaat tatccgatgt tcgcctgatt
    24601 tcaatggaag gtttaaaact ttctgtgatt gcttatcaga ccttgcgtct agcagcagag
    24661 gaacagggga aattggcatt tctagataca gtaaatccaa gcagacttag tcattatctt
    24721 caggcaatac aagagacgac aaccttcttc caaactcatt caaatgcatt aacattggct
    24781 gttgataacg atgaggcagg aagagaattt tgtcagaaac tgtcagataa aggacttccg
    24841 ctttctcaag atttaccacc attgcaagga cttgaaacaa agttagattg gaatgatatt
    24901 gtgaaacgac aaaaggaatt atctttaaga gatcttatcc agtcagccca aacaaaagtc
    24961 attagagatc atcctccacc taaacgagag cacacttttg atgtgataac aaaatcaagt
    25021 ccgctatcat aatctagaat gtgacaagga ggacacccta tgagtgtgat tgaacgtctg
    25081 gctgaaaaag tagctagaca agaagaaaag gtctcacgtg agacggagaa attggaacac
    25141 tatcgtgacc aactacaaac agctatgtac agtaccttta tcaaacggca acaatctagt
    25201 cagttgtcat ttcatgaagc actagagcaa gcctttggta aagaaaccac actacaccca
    25261 aattacagaa atgaggatac agaatgagta aaacatggaa ttttgatcag ccactagatg
    25321 atgtgaaacc aacatcatcc catgaagaac gagcaaaaat tgcagcactt ttccataaac
    25381 aagatgaaaa accaattgaa gaagtagact atgtggctgc ttttgaacag caacaaaagg
    25441 agtcagaatc taaagatgta cagacgcacg aatcaaaagt taaacaaagc cagccgaaga
    25501 aagtaaatat cacaagcgac tataaacaac acttggcaga cactattgca caaaacaaca
    25561 aggatatttc agcctgtcaa aagcaaattg aagaacttca tcaattgatt gatgaaaaga
    25621 aaatccaaaa taaaaagttg caggctattt cagtagccat tgatgattta taagtcaggt
    25681 agtcctatgc gggctacctt tttataattg aaggagaaga taatgaaatt ttttcaaaag
    25741 aaaaaacaga accaggatca atttaaacga ctgattcatc gactatcaga gatgtcagat
    25801 agtgaactaa ccaaagtaga gcaactccta gatgtggtct ttgattcaag tttcaagtct
    25861 agtgagagag tggaaatatc tagggacatt ataaccgatg aggaacaaat tcttgataag
    25921 tcaatccaag aagcgaaaaa taaactgaat actgagcagt tggagaagcg aatagaggag
    25981 tttaagcaat cgaagaaacc taaaaacgga taatgcacca aatatggtgc gttatccgtt
    26041 ttttatggta taatgaaagc aaatatgagg aggtctttat ctatgatcgg agacaatata
    26101 aaatcactac gccgaacaca cgatttaaca cagccagaat ttgcgaaaat ggttgggatt
    26161 tcacgcaata gcctgagtcg ctacgaaaat ggtaccagca ctgtttcaac tgaactcatc
    26221 gaccgtattt gtcagaaatt taacgtttct tatgtcgata ttgtaggaga ggacaagatg
    26281 ttaacacctg tcgaagatta ccatctgact ttaaaagtag aagtgataaa agaacgtgga
    26341 gcagccattt tatcaaagct ttatagatac caggatagtc aagatattgt ttttgatgat
    26401 gaatctaatc cttggatttt gatgagtgat gacttggccg aattgatcaa tacgaaaatt
    26461 taccttgtcg ctactttcga tgaaatagag cgttacaatg gctatttaga tggtatagag
    26521 cggatgttag acatggtgca tcatcgggtg gtggcttaat gagactggaa gaatttagtg
    26581 aggctgagtt tcagaaggcc ttgcagcgaa ccattcgggc cttaacccga ggaaagacga
    26641 ttccagatca accgaaagct attttgcttg gtggacaaag cggagcaggt aagacgacta
    26701 ttcatcgtat caagcaaaag gaatttcaag gtaatatcat tattatcgat ggtgacagct
    26761 accgttctca gcatcccaat tacttagccc tgcaagaaaa gtatggcaag gatagcgtgg
    26821 actataccaa gggatttgca ggaaaaatgg tagaacagtt ggttgatgaa ctcagtacgc
    26881 aaggctacca tttgctgatt gagggaacct tgcgaactac tcaagttcct cgtcagactg
    26941 ctcaattatt atcttctaaa ggttaccaag tttccttagc agtgattggt accaaaccag
    27001 agctttctta tctcagcacc ttgattcgtt acgaagagct ttatgccatc gatccgactc
    27061 aggctagagc aacaccaaaa gaacaccacg atgggattgt tgagaacttg gttgataact
    27121 tgagggagtt agaaagtgaa aatctctttg accagattca aatttatcaa agagatagaa
    27181 cttgtatcta tgattctgaa actgctgaag gttccgcagc agaagtgcta caagaatgcc
    27241 tatttggaaa atggagcaag gtagaggagg agatggtgaa ggagagtgaa ctcctactta
    27301 aggaattact tgagaaaaat aaataattga ttttaaagat aatatttttt tgggggttag
    27361 aattgcgagg atttaataat aagataaaat ctgtttatcg agaattaaca aataccaaag
    27421 agaaattcgg tagttttcat aagaccttga ttcatttaca tacacctgtt tcttatgatt
    27481 ataagctatt ttcgagctgg acttcaacga aatatagaaa aagtacagaa gatgaattat
    27541 ttgatatatt tttcaaaaat aagaaaatca aagttgataa aacaaaattt tttggtagct
    27601 ttgataaagt tatcttttct agcccaaaag agtacattag ttttcttttg ttagcagaag
    27661 ctatcttaaa aaatgaaata gaaatagttg tagtaactga tcataatact accaaaggta
    27721 ttaaaaaact tcaaacagca gtttcaatta taacgagaac ctatccgact tataatatac
    27781 atcctcatat tttacatgga gtagaaatta gtgcagcaga taagttacat attgtttgta
    27841 tatacgatca tgaaaaagaa tcttgggtta atcaatggtt atgtgaaaat attataagtg
    27901 aaaaagatgg aagttatcag cattcgttga ctatcatgaa agattttaat aatcaaaaca
    27961 taattaacta cattgctcat ttcaatagtt ataatatttt gaaaaaaggt tctcacttgt
    28021 cgggtgcata taagagacaa gtttttacaa aagaaaatac acgatttatt ggtgtaaaaa
    28081 atataaattc tgttgaagga tcgaaaaatc gtttattgac agattttaat tgtgaaccaa
    28141 attttttatt agataatgat tcacatgata ttgattcagt cggaaagaat aatatgtgga
    28201 taaaaggtgg aaagatttct tttaaaatgt tccaagaagc tttgcttgat tacactgtat
    28261 cagtaagttt atttgaacca aattttgaac aaaagtctta cataaaaggt ttatacattc
    28321 aaagtcgtgg aggcgataga agttttctta caggtgataa gttagaaaaa gatagagact
    28381 tctttttaac attctcacca tctatgaact gtttaattgg agggagaggt acagggaaaa
    28441 gtacactaat agatatgtta caatttgtac tttctcagga ttgcgacaag cagagtaaat
    28501 tagaattcct atgtaaccat gcaaatgctt ttgtactcta tgttttagag gatgctgaat
    28561 atatcattga ggttagtttg ccagatgtct tgcaggaaaa tagggacaat atcttacaat
    28621 attatgggca aaatcgtgag aataggtatg gatatcctta taactacaat tctgactcta
    28681 tcaaagagtg gacacgctct caatatacga aagtatacaa agttgaggga aaatttttca
    28741 aattagttga taaaactaga atattagaaa aaatgtttga taggagatat tctgttaatg
    28801 agttggttag aacagcggat ggagaaaaaa ttacagaatt tatttccgac ttaatgctaa
    28861 aaaataaaaa tttaccgaga ccaaactatg gtttaagaac tcagactcta gaatcattcg
    28921 aagctaaact acaggaactt gataaatata ggagagttcg taaggattca atactcaaaa
    28981 taattgatga tttcaatcaa actcaagttg gtaagttaag aatctgttat gagcaaattg
    29041 atagatggga agtaccagat tttgaaagca ctcttttcaa aagtaattca actctcaatt
    29101 tctcatttga aaattataga attagtaagc gggatgttgc agatattcta taccttgttt
    29161 atcaggagtt aggaataaaa ggatttgtta acgttattt
//
LOCUS       DBNFCO010000018        27835 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.018, whole genome shotgun sequence.
ACCESSION   DBNFCO010000018 DBNFCO010000000
VERSION     DBNFCO010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 27835)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27835)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27835
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.018"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            39..854
                     /locus_tag="AC1PIV_000683"
     CDS             39..854
                     /locus_tag="AC1PIV_000683"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HIP6611723.1"
                     /translation="MNQQFSLDQFSLKGKIALVTGASYGIGFAIASAYAKAGATIVFN
                     DINQELVDRGMAAYKAAGINAHGYVCDVTDEDGIQAMVAQIESEVGIIDILVNNAGII
                     RRVPMIEMTAAQFRQVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRETV
                     SAYAAAKGGLKMLTKNIASEYGEANIQCNGIGPGYIATPQTAPLRELQKDGSRHPFDQ
                     FIIAKTPAARWGEAEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPEA"
     gene            905..1546
                     /locus_tag="AC1PIV_000684"
     CDS             905..1546
                     /locus_tag="AC1PIV_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HIP6611724.1"
                     /translation="MKIALINENSQAAKNSLIFETLKSVTDAKGYHVFNYGMYGKEGE
                     SQLTYVQNGLLASILLVSKAADFVITGCGTGVGAMLAANSFPGVVCGFAVDPTDAYLF
                     SQINGGNALSLPFAKGFGWGAELNLKLLFERLFAEEMGGGYPRERVIPEQRNARILNE
                     MKAVTYKDLLTVLQEIDQDFLKETISGEHFQEYFFANCQDESIATYLKTVLES"
     gene            1563..2564
                     /locus_tag="AC1PIV_000685"
     CDS             1563..2564
                     /locus_tag="AC1PIV_000685"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HIP6611725.1"
                     /translation="MKKVLLIGEPLIRITPTNYQELTDGVESRVFFGGSEINVACNLQ
                     GFGCETKLLTALPQGSLGNRFLDFLDGKGIDTSSVQRKGERVGVYYMEAGFGCRSSQV
                     YYDRGQSSLEAIQVDHFDMEQLFLEVGLVHFSGITVAIGSAVRAWLVQVLKEAKRRKI
                     PISMDLNWRSKMIGLRDAKKVFSQFATYADYCFGLEPIMANEKDWELFERDTATVHTI
                     RERMQTLKEAYKFQAIFHTIRQTDELGRNLYKAYGLADEFCCSQELKTQVLQRVGSGD
                     AFVAGALYKLLEGTSLKAILDFAVASGTYKCSIEGDHMRQSLRKVESLLEGKNDIIR"
     gene            2575..3216
                     /locus_tag="AC1PIV_000686"
     CDS             2575..3216
                     /locus_tag="AC1PIV_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HIP6611726.1"
                     /translation="MSPSQIISKLKEQGLVVVVRGDDKEVGFKTAQACIAGGITAIEV
                     AYTNPDANMIITELSRCHKDDVSVLIGAGTVLDSVTARQAIMAGASYIVSPSFNIEVA
                     KICHLYAVPYLPGCMTLTEITNALEAGCEMVKLFPGSVLGANYITAIKGPLPHVSIMV
                     TGGVKLNNVSEWFNAGATVLGIGGEFNQLATKGEFGTIQELASSYTSVRDKMK"
     gene            3503..3937
                     /locus_tag="AC1PIV_000687"
     CDS             3503..3937
                     /locus_tag="AC1PIV_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HIP6611727.1"
                     /translation="MIKVIVVAHGQFASGILTSLKLIAGEVENIEAIDFSEGMSAQEL
                     KARIKSAILGEREVLILTDLLGGTPFKVSVELATEQKEQNVVVLSGLNLAMILEANFS
                     RLTDDLEQLVGKLITTSKDGIVDSVSLLAEDNHDEELFEDGI"
     gene            3949..5139
                     /locus_tag="AC1PIV_000688"
     CDS             3949..5139
                     /locus_tag="AC1PIV_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HIP6611728.1"
                     /translation="MIKDVLIESIAKKREFRNSTLLSKKEVVAAIELAIQQLVINCEY
                     FGESFPTPATFDNHYPKMDNTEWTNGFWTGALWLGHEYSLNNEMKALAKKNTTSFLER
                     VKQRIELDHHDLGFLYSPSTVADYKLTGSKEALEASLLAADKLMERYQEKGGFIQAWG
                     QLGKAEDYRLIIDCLLNLQLLFFAYEETGEQKYYDVALSHFYASVNTVIRDDASTFHT
                     YYFDPETGKPLKGVTRQGFSDDSSWARGQSWGIYGIPLAYRKIKDPACLNLFKGVTNY
                     FLNRLPEDNVSYWDLIFNDGSGHARDSSATAIAVCGIHEMLKYLPEVDEDKETYKYAM
                     HTMLRSLIDNYANRELAPGRPLLLHGVYSWHSGKGVNEGNTWGDYYYLEALLRFYKDW
                     ELYW"
     gene            5149..5640
                     /locus_tag="AC1PIV_000689"
     CDS             5149..5640
                     /locus_tag="AC1PIV_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HIP6611729.1"
                     /translation="MATPNIVMARIDERLIHGQGQLWVKSLGCNTVIVANDKVSEDKI
                     QQTLMKTVIPDSVAMRFFSLQKVIDVIHKANPAQTIFLVIKDLQDALALVKGGVPITE
                     LNIGNIHNAPGKMQVTRSIFFGSEDKAIVRELNDVYKIRFNTKTTPSGNDGAVEVNIL
                     DYI"
     gene            5659..6435
                     /locus_tag="AC1PIV_000690"
     CDS             5659..6435
                     /locus_tag="AC1PIV_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HIP6611730.1"
                     /translation="MTISLIQAALIGLWTAFCFSGLLLGLYTNRCIVLSFGVGIILGD
                     LPTALAMGAISELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVTPEAALALST
                     PIAVGIQFLQTSAYTLHAGAPESAIKHLRAGNLSKFKRVANGTVITFAFLGFALGFLG
                     AYSMDTLLKLVEMIPPVLLTGLSVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLQLPVIGIAIVGSIFALKEFFNKPEQVAVKQEEAHDDWI"
     gene            6422..7237
                     /locus_tag="AC1PIV_000691"
     CDS             6422..7237
                     /locus_tag="AC1PIV_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000147944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HIP6611731.1"
                     /translation="MTGSKLTKKDYLNTSLRAFFLQNGFNYSNYQGIGYANVMYPAFK
                     KHFGDDKEGLTKALEENCEFYNTNPHFLPFITSLHLVMLENDLPEEETRGIKMALMGP
                     LAGIGDSLSQFVLAPLLSTIAASLAGQGLVMGPILFFLGMNIILTSIKLLTGLYGYKF
                     GTSVIDKLSDQMATISKVANIIGVTVISGLAVTFVKISVPITFAAGELTEGADQKIVT
                     IQGMLDKIAPALLPALFTILVYYLIKNKKWTTYKLVILTVIIGILGSWLGILA"
     gene            7244..7552
                     /locus_tag="AC1PIV_000692"
     CDS             7244..7552
                     /locus_tag="AC1PIV_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HIP6611732.1"
                     /translation="MEQQTLYYVLIILVALSTILPVLTSYVNRKRQQKALEEQLEKRQ
                     RYLSTLQAGDEVILFSGLHGKIIKLTDSLVELQIAEGVLVYVEKESIMGKAKELLFTK
                     "
     gene            7649..11170
                     /gene="hylA"
                     /locus_tag="AC1PIV_000693"
                     /pseudo
     CDS             7649..11170
                     /gene="hylA"
                     /locus_tag="AC1PIV_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936069.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronate lyase"
     gene            11430..13406
                     /locus_tag="AC1PIV_000694"
     CDS             11430..13406
                     /locus_tag="AC1PIV_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009910066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heparinase II/III domain-containing protein"
                     /protein_id="HIP6611733.1"
                     /translation="MNFEEWIWALPSLSSFGEAIEKGLVMQTIFGKIVANQSAESVKT
                     YILNQQDAAYKELLLSCQNLLNDIFIFEDNWDMEPCSVGYHLAPLDWTADCHGDEEWT
                     FMLNRQEYLWKLVLAYLVEKDSRYMEQVKRFIFSWIEQVTDWYPKRTSSRTLDTAIRC
                     LSWLNILPFLIDWGGLSEAERSQLLVSIQKQLSYLHSHYRAKDTLSNWGIFQTGAMLL
                     AHAYIGDQVDLVELHHFARQEIEEQIQTQILEDGTQFEQSFLYHVEVYKLLLGLAFSL
                     PDYRKQWTSILKKMADYVLQMTGPDGKSVALGDSDVHCTSDILQMTAIFFEDGTYLVD
                     NSKLDLGVLFLVGENGLRIFEHLTAQSSSSGGQHFSESGHSIVKEVDSYLCFKAGPMG
                     SAHSHSDQNSLCFYHKGQPIVIDSGRFSYRECEERYLLKSAWAHSTCILDDNAPGQIK
                     GSWEYDTYPQFISHSYKGFEHCHWMQGIYQAQTSQGLPYWHKRQLLMVGGDLLLIVDS
                     VDCSGQHELISQLILDERVKIGEERLNDLRLYSQKDFEIQKTVRSPRYNQLVETNKLV
                     KKESFQDRLVTFTLLADEAIRVKQLPVYQTDYHLIESGLAFSCQGKGLNILLVVSDND
                     ICKGEKLLQVAGYKLRGKCLVVDRDKRQVVRLKN"
     gene            13503..14504
                     /locus_tag="AC1PIV_000695"
     CDS             13503..14504
                     /locus_tag="AC1PIV_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HIP6611734.1"
                     /translation="MSEKFTIKDIAELAQTSKTTVSFYLNGKYEKMSKETRERIERVI
                     RETDYKPSVVARSLNSKNTKLIGVLIGDITNTFSNQIVKGIEEEAHKSGYQVIIGNSN
                     YNQESEDKYIESMLMLGVDGFIIQPTSHFRKYSRIIEDKKKHMVFFDSQLYEHRTSWI
                     KTNNYDAVYDATQLCVENGYQKFILITADISRLSTRIERATGFMDALLDCKQSYQDLT
                     IADENTDIEEIKCFLQGVVNPQEKTLVFVPNCWALPLVFNAMKELKYDFPQVGLLGFD
                     NTEWTNFSSPTISTIVQPAFEEGCQATRMLINQIEGGNQVGRQQVLDCTVHWKDSTF"
     gene            complement(14940..15899)
                     /gene="nrdF"
                     /locus_tag="AC1PIV_000696"
     CDS             complement(14940..15899)
                     /gene="nrdF"
                     /locus_tag="AC1PIV_000696"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HIP6611735.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLTAEEKDLVGKVFGGLTLLDTLQSETGVQALRNDIRTPHEEAVYNNIQFMESVHAK
                     SYSSIFSTLNTKSEIEDIFEWTNSNEYLQRKAKIINEIYETGTPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELSEEEQDKLR
                     DWMYDLLYQLYENEEGYTRSLYDAVGWTEEVLTFLRYNANKALMNLGQDPLFPDSADD
                     VNPIIMNGISTGTSNHDFFSQVGNGYLLGEVEAMTDDDYLYGL"
     gene            complement(15926..16120)
                     /locus_tag="AC1PIV_000697"
     CDS             complement(15926..16120)
                     /locus_tag="AC1PIV_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611736.1"
                     /translation="MFGFGKTKQENKKLKRENNVLKKAYSQTKKENNKLKKTSDRLAA
                     DGLRHGSPEAGKYLVGKRKK"
     gene            complement(16166..18325)
                     /gene="nrdE"
                     /locus_tag="AC1PIV_000698"
     CDS             complement(16166..18325)
                     /gene="nrdE"
                     /locus_tag="AC1PIV_000698"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HIP6611737.1"
                     /translation="MSLKELGDVSYFRLNNEINRPVNGQIPLHKDQEAVKAFFTENVL
                     PNTKQFDSILDKIAYLLEENYLEKEFLDQYSPEFIIKIDQFLKDQNFRFKSFMAAYKF
                     YNQYALKTNDGAYYLESMEDRVLFNALYFAEGDEELALNLANEMIHLRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGISLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLDVFHPDIISFLSTKKENADEKVR
                     VKTLSLGITVPDKFYELARKNEDMYLFSPYSVELEYGVPYSYLDITEKYDELVANPRI
                     RKTKIKARDLETEISKLQQESGYPYVINIDTANRSNPVDGKIIMSNLCSEILQVQTPS
                     ILNDSQEYLSMGTDVSCNLGSTNIVNLMKSPDFGRSVRTMTRALTYVTDHSHISAVPS
                     IEAGNSQAHSIGLGAMGLHSYLAQNLIDYGSKTAVEFTNIYFMLLNYWTLVESNNIAR
                     ERKATFHNFDKSKYADGTYFDKYVTGDYQPQSDRVKELFEGIFIPSGQDWAELREKVM
                     ADGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLTTETI
                     PFYKSAYDMDMRKVIDVYAAATEHVDQGLSLTLFLRSELPKELYEWKKENKQTTRDLS
                     ILRNYAFNKGIKSIYYIRTFTDDGEEVGANQCESCVI"
     gene            complement(18358..18576)
                     /gene="nrdH"
                     /locus_tag="AC1PIV_000699"
     CDS             complement(18358..18576)
                     /gene="nrdH"
                     /locus_tag="AC1PIV_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HIP6611738.1"
                     /translation="MVTIYSKNDCVQCKMTKKFLDQHSVDYKEINLDEQPEFIDHVQG
                     LGFSAAPVIETENDVFSGFQPGKLKALV"
     gene            18963..21632
                     /gene="acnA"
                     /locus_tag="AC1PIV_000700"
     CDS             18963..21632
                     /gene="acnA"
                     /locus_tag="AC1PIV_000700"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003994 - aconitate hydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aconitate hydratase AcnA"
                     /protein_id="HIP6611739.1"
                     /translation="MEKTQRKRLFYKGEEYSYYALESISMEEKVDIHSLPYTIRILLE
                     SLLRKEDGVDVTKNHIMELLHYQAASPKGEIPFKPSRVILQDFTGVPVVVDLASMRDA
                     VVKAGGNPELINPEIPVDLVIDHSVQVDFFGTEDALEKNIALEFERNNERYEFLKWAE
                     NSFENYRAVPPATGIIHQVNIEFLSDVIINKDGLLYPDSMFGTDSHTTMINGIGVLGW
                     GVGGIEAEAAMLGEASYFPVPEVIGVRLDGQLPKVATATDLALKVTQLLRQENVVGKF
                     VEFFGPGLSSLTLADRATVSNMAPEYGATCGYFPIDGETLHYMRLTNRSEEHVELTEA
                     YAKANYLFYDAERFPSYSKVLELDLSTVVPSISGPKRPQDLIELTDAKAEFQASLIRE
                     VGVRGFGLEEAELDKTASVKYVEGDEQIQTGHVAIAAITSCTNTSNPYVLLAAGLLAK
                     NAVEKGLAVSKTVKTSLAPGSKVVTGYLKKSGLQTYLDTLGFNLVGYGCTTCIGNSGD
                     LCPEVAEAIKEEDLLVSAVLSGNRNFEGRINPLVKANFLASPPIVVAYAIAGNMNVDL
                     TRDPLGYDEKQQAVYLADIMPSREEVDDYIERYVTRDLYKEEYQQVFTDSQAWNAIET
                     KINKNYNWNSSSTYIQNPPYFDNMQADLSIKPLENLSVLAKFGDSVTTDHISPAGNIA
                     RLSPAARYLEENGIVYKDFNSYGSRRGNHEVMIRGTFANIRIKNELADGKIGGWTRVG
                     EEILPIYDAAMRYKEVGVGSIVIAGKDYGMGSSRDWAAKGSSLLGVKAVLAESFERIH
                     RSNLVMMGVLPLQFLEGQSAESLGLTGHESYTIDLPEDVGVGQIVTVHAQTDDVTKEF
                     QALVRFDAEADIRYYRHGGILPMVVRKKLGGKV"
     gene            21629..22747
                     /locus_tag="AC1PIV_000701"
     CDS             21629..22747
                     /locus_tag="AC1PIV_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate synthase"
                     /protein_id="HIP6611740.1"
                     /translation="MTETNGLKDAIACDTRISAIENDRLSYAGYDIAELMENNASFEE
                     VIYLLWNLHLPTQIELNYFEKSLRKEYAISDAVEQCILIQSRRHLHPMSVLRSTVSLL
                     GVYNVHAEENSLEALYEQSIQIMAKVPTIIATFARLRRGLVPIEPRSDLGFAANFLYM
                     LNGEEPSDLQIKAFNKALVLHADHELNASTFAARVTASTLTDLYSCVTTAIGTLKGSL
                     HGGANERVFDMLLAIRESGDTERYLQKKLDSKEKIMGFGHRVYKTVDPRQEYLKEMAR
                     DLTFGTDDEAFYRLSEEVESFIKTKKGLIPNVDFYSATVYHVLGIDSDIFTLIFAMSR
                     MAGWIAHVQEQRKNNKLIRPRSSYLGGRNLVYIPIGKR"
     gene            22750..23931
                     /gene="icd"
                     /locus_tag="AC1PIV_000702"
     CDS             22750..23931
                     /gene="icd"
                     /locus_tag="AC1PIV_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019780541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004450 - isocitrate dehydrogenase (NADP+)
                     activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent isocitrate dehydrogenase"
                     /protein_id="HIP6611741.1"
                     /translation="MAEKILMREGRLIVPDCPVIPYIEGDGIGRDIWSVSQKVIDAAV
                     KKAYAGQRSIQWREVFAGEKAYELMGTSLPNETLEIIREHLVAIKGPLGTPIGKGHRS
                     LNVALRQELDLYACVRPIRYFKGVPSPLKEPEKTDITIFRENTEDIYAGIEWEAGSDE
                     VAKVISFLQEEMGVVNIRFPESSSIGIKPISEEGSKRLIRSAIEYALEHQLKMVTLVH
                     KGNIQKFTEGGFRKWGYELAKEEFATELAEGTLVVNDIIADNFLQQILLAPENFQVVA
                     LTNLNGDYASDALAAQVGGIGISPGANINYQTGHAIFEATHGTAPDIAGKDLANPCSL
                     LLSACMMLEYIGWKEAAVLIIQALEDAFINKNVTLDFAKILDVAHQSTSQFSEVLIDS
                     I"
     gene            24087..24350
                     /locus_tag="AC1PIV_000703"
     CDS             24087..24350
                     /locus_tag="AC1PIV_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HIP6611742.1"
                     /translation="MASKDFHIVAETGIHARPATLLVQTASKFASDITLNYKEKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAITETMEKEGLA"
     gene            24355..26088
                     /gene="ptsP"
                     /locus_tag="AC1PIV_000704"
     CDS             24355..26088
                     /gene="ptsP"
                     /locus_tag="AC1PIV_000704"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HIP6611743.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETVTVEDTNAEEARL
                     DAALEASQNELSVIRENAVASLGEEAAAVFDAHLMVLADPEMIGQIKETIRAKKTNAE
                     TGLKEVTDMFIAIFEGMEDNPYMQERAADIRDVAKRVLAHLLGVRLPNPATIDEESIV
                     IAHDLTPSDTAQLNKQLVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     VLAVNGITGDVVINPSEEVIAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNDNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDLPHEMNPFLGFRALRISISETGNQMFRTQLRALLRSSVHGKLRI
                     MFPMVALLTEFRAAKAILDEEKANLLAEGVAVADDIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYAHRALTECATAEEV
                     LELQKEYVDFD"
     gene            complement(26170..27657)
                     /locus_tag="AC1PIV_000705"
     CDS             complement(26170..27657)
                     /locus_tag="AC1PIV_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HIP6611744.1"
                     /translation="MKKIAFDSTKYLNLQRDHILERIAQFEGKLYMEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKDQVEIVIAINASNIEHSKARGDLGISYDQEVFRLIDTF
                     NDIDIYVGSVVITQYRNQPAADAFRKQLEKHGIKSYLHYPIKGYPSDIDHIISPEGMG
                     KNDYIETSRNLVVVTAPGPGSGKLATCISQLYHDQLHGVTSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDLNMIDPFHLQTYGKTAVNYNRDIEVFPVLNRTFERILNKSPYA
                     SPTDMGVNMVGYSIVDEEAAIEASKQEIIRRYYQTLVDFKAERVSEQAVKKIELLMNE
                     VGVTPADRKVVIAAREKAELTTSPALAIQLPTGEIVTGKTSDLLKPTATVLLNAIKQI
                     ANIDDETLLIEPNYIRPIQELKADYLDKTNTRLDASEILNALAITAQDSPLAARAMKE
                     LGQLNGSEAHSTVILSDEDKSVLRKLGINLTFDPIYQHNKFYQKN"
BASE COUNT         8253 a         4934 c         6449 g         8199 t
ORIGIN      
        1 aaacgcttta caaattaaaa tacaagggag ttacgaatat gaatcagcaa ttttcattgg
       61 atcaattttc tctaaaggga aaaattgctt tggtaacagg ggcgtcgtat gggattggct
      121 ttgcgattgc atcggcctat gcaaaagcag gggcgacaat tgtttttaat gatattaatc
      181 aagagttggt tgatagagga atggcagcct ataaggcagc tggtattaat gcgcatggct
      241 atgtttgcga tgtgactgat gaagatggaa tacaggctat ggttgctcaa attgaatcag
      301 aagttggaat tattgatatt ctagtgaata atgctggtat tattcgtagg gttccaatga
      361 ttgaaatgac agcggctcaa tttcgccaag ttattgatat tgacctaaat gctccgttta
      421 ttgtttctaa agcggttatt ccatctatga ttaaaaaggg gcatgggaag attatcaata
      481 tttgttccat gatgagtgag ttaggacgag aaacagtgtc tgcttatgca gcggctaagg
      541 gtgggcttaa gatgttgacg aagaatattg cttcggaata cggtgaagca aatatacaat
      601 gtaacggcat tggtcctggg tatattgcaa ctccacaaac agctccgtta cgtgaactcc
      661 agaaggatgg ttctcgtcat ccatttgatc aatttattat cgcgaagacc cctgcagctc
      721 gttggggtga agctgaggat ttgatgggtc cagcagtctt tttagcaagt gatgctagta
      781 attttgtgaa tgggcacatt ctttatgttg atggaggaat tctcgcttac attggtaaac
      841 agccggaagc gtaataaacg aattaacaaa tttaacaaat tttgatataa gaagggaaaa
      901 aacgatgaaa attgcactta ttaatgaaaa tagtcaggct gctaaaaata gtcttatttt
      961 tgaaacattg aagtcagtaa cagatgctaa agggtatcat gtttttaact atggaatgta
     1021 tggtaaagag ggagaaagtc agttgactta tgtacaaaat ggtctgttgg cttcaatcct
     1081 tctagttagt aaggcagcgg attttgttat tacaggttgt ggcacggggg taggtgccat
     1141 gttggcggct aatagttttc caggggtagt ttgtggcttc gcggtagatc cgacggatgc
     1201 atacctcttt tcacagataa atggaggaaa tgctttgtct ctgccatttg caaagggatt
     1261 cggttgggga gctgaattaa atctcaaatt actttttgag cgactgtttg cagaggaaat
     1321 ggggggcgga tatccccgtg aacgcgttat tccagaacaa cgaaatgctc gtattttgaa
     1381 tgaaatgaaa gcagtcacct ataaagactt actgacagta cttcaggaaa ttgatcaaga
     1441 ttttttgaaa gaaactattt caggtgaaca tttccaagaa tatttctttg ccaactgtca
     1501 ggacgagtca attgcaacat atttaaaaac agtattagaa agttaaagag tggggggcgg
     1561 ttatgaagaa ggtattactg attggtgaac ctttaattcg cattacacca acaaattatc
     1621 aagaattgac agatggtgta gaaagtcgtg tgttttttgg aggttcagaa atcaatgtcg
     1681 cttgtaatct tcaaggattt ggatgtgaaa ccaagctttt gaccgcacta ccacaaggct
     1741 ctctaggtaa tagattttta gatttcttag atgggaaagg gattgatact tccagtgttc
     1801 aacgtaaggg ggaacgtgtg ggggtatact acatggaagc aggatttggt tgccgttcta
     1861 gtcaagtcta ctatgatcgt ggccagtcta gtttggaagc tattcaagtc gatcattttg
     1921 atatggaaca attattttta gaggttgggt tggttcactt tagtggtatc accgtggcta
     1981 ttggttcagc tgttagggca tggcttgttc aagtattaaa agaagcaaag cgtcgtaaaa
     2041 ttccgatttc gatggatctt aattggcgtt ctaagatgat tggattaaga gatgcaaaaa
     2101 aagtgttctc gcaatttgcg acctatgcag actattgttt tggtctggaa cctattatgg
     2161 ctaatgaaaa agattgggaa ttatttgaaa gagatacggc tactgtccat acaataagag
     2221 aacggatgca aactttaaag gaagcctata agttccaagc aattttccat acgattaggc
     2281 agacagatga actaggcaga aatttgtata aggcttacgg attggctgat gaattttgtt
     2341 gctctcaaga attgaaaact caggtgttac aacgtgttgg cagtggtgat gcgtttgttg
     2401 ctggggcatt atataaattg ttagagggga cgtcgttaaa ggctatttta gattttgcag
     2461 ttgctagtgg aacttataaa tgtagcatag aaggggatca catgcggcaa tctcttagaa
     2521 aagttgagtc tttattagag gggaaaaatg acattatacg ataaaggaga aaaaatgagt
     2581 ccatcacaaa ttatttcaaa attgaaggag caagggcttg ttgtagtcgt tagaggagat
     2641 gacaaagaag tcggatttaa gacggcacag gcctgtattg caggaggaat tacagctata
     2701 gaggttgctt atacaaatcc tgacgcgaat atgattatta cagaacttag tcgatgccat
     2761 aaagatgatg tttctgtttt aattggggct ggaacggttc tagattcagt aacggcacgg
     2821 caagccatta tggcaggagc aagttatatt gtttcaccat cttttaatat agaagttgca
     2881 aaaatctgtc atctttatgc agtgccatat cttccgggct gtatgacttt aacggagatt
     2941 acaaatgctt tggaagcagg ctgtgaaatg gttaaactgt ttcctggtag tgttttgggg
     3001 gcaaactaca ttactgcaat caaaggacca ttaccgcatg tttcaatcat ggtaaccggt
     3061 ggagtaaagc ttaataatgt ttcagaatgg tttaacgctg gtgcaactgt tcttggtatc
     3121 ggtggggaat ttaatcaatt agctactaaa ggagagttcg gtacaattca agaattagcg
     3181 tcctcttata caagtgttag agataagatg aagtagttta tttcaaaata aggactgtat
     3241 ttttaacgtt ttcactttct cctgcctcca acggggttga atgtgggaga aagtgagatg
     3301 ttacagggga aattttgaac ggaaacatgg agatatttgg tactcctgtt tatgaaaaga
     3361 gggagctgga gaatattttt taaataaaag tccaacgaaa tataaaacgc ttacattttt
     3421 ttataaaatc tattgacaag tggttgtcaa tagtctacaa tacaaagtgt aggtaaaccg
     3481 gtaaagttaa aaggagagaa ttatgattaa agtgattgtc gttgctcatg gacagtttgc
     3541 tagtgggatt cttacttcac taaagttaat tgcaggagag gtggagaata ttgaggcaat
     3601 tgattttagt gaaggaatgt cggcgcaaga actaaaagca cgcatcaaat cagctatatt
     3661 aggcgaaaga gaagttttga ttttaactga tttactagga ggtacgcctt ttaaagttag
     3721 tgtagaatta gcaacagaac agaaagagca gaatgttgtc gttctttcag gtttaaatct
     3781 tgcgatgatt ttggaagcga atttttcacg gttaacagat gatttagaac aattggttgg
     3841 taaattgatt accacctcta aagatggaat cgttgattcg gtcagtctgt tagcagagga
     3901 taaccatgat gaagagttat ttgaagatgg tatatgaggg agaaatgcat gattaaggat
     3961 gttttgattg agtcaattgc taaaaaaaga gagtttagaa attccactct attgagtaag
     4021 aaagaagttg tggctgcaat agaattggcg attcaacaac ttgttatcaa ttgtgaatat
     4081 tttggtgaat cgttcccgac tccggccaca tttgataacc attatccaaa gatggataat
     4141 acagagtgga caaatggttt ttggacgggc gcgctttggt taggacatga gtattctttg
     4201 aacaatgaaa tgaaagcgtt agcaaaaaag aatacgacat ctttcttgga acgtgtcaaa
     4261 caaagaattg aattagatca tcatgatttg ggatttctgt attcaccatc aacggtagct
     4321 gattataaat tgacaggtag taaagaggct ttagaggctt cgctcttggc tgctgataaa
     4381 ttaatggagc gctatcaaga aaagggaggt tttattcagg cctgggggca acttggtaaa
     4441 gcagaagatt atcggttgat tattgattgt ttgctgaatt tacaattact tttctttgct
     4501 tatgaggaga caggtgagca gaaatattat gatgtagctc ttagtcattt ctacgcttct
     4561 gttaatacag ttattcgaga tgatgcttca acatttcata cctattactt tgaccctgaa
     4621 acaggaaaac cgctcaaagg ggttacccga caaggattta gtgatgactc ttcctgggcg
     4681 cgtggtcaat cttggggtat ttacggtatt ccgttagctt accgtaaaat taaagatccc
     4741 gcatgtttaa atttgtttaa aggagtaacc aactactttc ttaatcgttt gccagaggat
     4801 aacgtttcct attgggattt aatttttaat gatggtagtg ggcacgctcg tgattcttct
     4861 gcgacagcaa tagcggtttg tggtattcac gagatgctta aatatttgcc agaagttgat
     4921 gaggacaagg aaacttataa atatgctatg cacacgatgc tacggtcctt gattgataac
     4981 tatgctaatc gtgagttagc tccaggtcgt ccattgcttt tacatggggt ctactcttgg
     5041 cattcaggaa aaggtgtcaa tgaaggaaat acttggggcg attattatta cttagaagct
     5101 ttgcttcgtt tttataaaga ttgggaatta tattggtagg aggttaaaat ggcaacacca
     5161 aatattgtaa tggctcgtat tgatgagcga ctaattcatg gacagggaca actatgggtt
     5221 aaatccttag gttgtaatac tgtcatcgtg gcaaatgata aggttagtga agataagatt
     5281 cagcagacat taatgaaaac ggttattcca gattcagtag ctatgcgttt cttctctttg
     5341 cagaaagtga ttgatgtgat tcataaggct aatcctgctc aaactatttt cttagttatt
     5401 aaagatttgc aagatgcact agctttggtt aaagggggag taccaatcac agaattaaat
     5461 attggaaata ttcataatgc gcctggaaaa atgcaagtaa cacggtctat cttttttggt
     5521 tcagaagata aggctatagt gagagagttg aacgatgttt ataagattcg cttcaacaca
     5581 aagacaacgc cttctggtaa tgatggggca gttgaagtta atatattgga ttatatttaa
     5641 aaaataagga gaattatcat gacgatcagt ctaattcaag cagctcttat tggtctgtgg
     5701 acagctttct gttttagcgg tctattattg gggctttaca caaaccgatg tatcgtgctt
     5761 tcttttgggg tcggaatcat tttaggagat ctaccaacgg ctttagctat gggtgctatc
     5821 agtgagctgg catacatggg atttggtgtt ggtgctgggg ggaccgttcc tccaaatcca
     5881 atcggacctg gtatttttgg tactttgatg gctattacaa gtgctggaaa agtaacacca
     5941 gaagcagctt tagcactttc aacacctatt gcggtaggta ttcaattctt acaaacttca
     6001 gcatatactt tacatgcggg tgctccagaa tcagctatca aacatcttcg tgcaggaaac
     6061 ctttctaaat ttaaacgtgt tgcaaatggt acagtgatta ctttcgcctt tttaggattt
     6121 gctcttggtt tcttgggtgc ctattcaatg gatactcttt tgaaattggt tgaaatgatt
     6181 ccaccagtat tattaaccgg attgagtgta gcaggtaaga tgcttccagc tatcggtttt
     6241 gcaatgattt tgtctgtaat ggctaagaaa gaattgatcc cgtttgtatt gcttggctat
     6301 gtttgtgcag cttatctaca actgcctgta attggtatcg caattgtcgg tagtatcttt
     6361 gcacttaaag aattctttaa taaaccagaa caagtggcag tgaaacagga ggaagcacac
     6421 gatgactgga tctaaactaa ctaaaaaaga ttatctcaac acttctttac gggccttctt
     6481 cttgcagaat ggtttcaatt acagtaatta tcaagggatt ggctatgcaa atgtcatgta
     6541 tccagctttt aagaagcatt ttggtgacga caaagaagga ttaactaaag ctttagaaga
     6601 aaactgtgag ttttacaata ccaatccaca ttttcttcca ttcattacta gtcttcattt
     6661 ggtcatgtta gaaaatgatc tcccagaaga agagactcgt gggattaaga tggctctgat
     6721 ggggccgttg gcaggaattg gtgactcact ttcacaattt gtattagccc cacttttatc
     6781 tacgattgct gcctctctag caggtcaagg actggttatg ggaccgattc ttttcttcct
     6841 tggaatgaac attatcttga cctctatcaa gttgttgact ggtttgtatg gctataaatt
     6901 tggtaccagc gtgattgata agttgagtga ccaaatggca acaatttcta aggtagccaa
     6961 tatcatcggt gtgacagtta tctctggttt agcagtaacc tttgtaaaaa tttcggtgcc
     7021 aattaccttt gcggcgggtg aattgacaga aggagcagat cagaaaattg tgaccatcca
     7081 gggaatgctc gataagattg cccctgcatt gcttccagcc ttgtttacga ttttggttta
     7141 ctatctcatc aagaacaaga aatggacaac ctacaaacta gttatcctga cagttatcat
     7201 cggtattttg ggtagctggc tgggcatcct tgcataagcg cctatggaac aacaaactct
     7261 ctactatgta ctaattattt tagtagctct atcgaccata cttcctgtac tcacttctta
     7321 tgtcaatcgt aagcgacaac aaaaagcact tgaggagcaa ctggaaaaac gccaacgcta
     7381 cttatcaacc ttacaggctg gagatgaggt tatcctcttc tctgggctgc atgggaaaat
     7441 catcaaacta acagacagct tggtagaatt gcagattgca gaaggtgttc ttgtttacgt
     7501 tgaaaaagag tcgattatgg gaaaagccaa agaactactt tttacgaagt agttcttctt
     7561 tcttgcctcc gcaaggaagc ggttgcagga ttaaaattat acccctggga cattgttttg
     7621 ccccgcataa aaaggaaagg aaacaccaat gggatttttt atcagtcaaa gcaagcagca
     7681 ttacggcatc cggaaatata aggtgggtgt ctgctccgcc cttatcgcgc tgtctatctt
     7741 gggaacaagg gttgcagcca atcaactgcc aagtacagaa acagctagtc cacaaagcag
     7801 tcagttagtg gaaacaactc cagaaacgac agaagcagtt aatcttacga cagaagcagt
     7861 aatgacaagc gaggtcagct ctgaggttag tcctgttaca tcaacagaaa cccagccttc
     7921 aagcaccgct gcagaaactc ttgctagtcc gcaagctgtt caggcgacaa aagaagaaga
     7981 gaagaaccta gtagccaacg gggagttcgc cagtacaaca gcagcatcag gaaattgggc
     8041 agatccggca gctacaaact gggaaacatg gattcctgca aatgtgaaga aagaaaacgg
     8101 acaggttcgc attgatgagg gacggctgca tatctcttca acagctagct atcgagtggc
     8161 agtgcaccaa acagtggatg tagatcctaa caagcgctat ctctttagct ataatgtaga
     8221 aaccaaggac ctgaaaggga gcggtgttcg tgttcgcttg cgtagtttga ctgcagaagg
     8281 taaggacttg agtccacaag aatttgccta tacaccttat aaaaatggaa gtcaagcgga
     8341 gcacatagag cagatcttga cggtatctcc ggaaactcgt aaattgaagg tggaactgtt
     8401 ttttgagaat agtgtcggcc aagcctggct ggataacatc tcgctggtcg aatacgtaga
     8461 aaagacacca gaaacaccag agccaagcct agaacttgtc caacctgaaa cagggcaaat
     8521 aagtcttgcc agcaacaagg tctacctgcc tgttcggcca gacctgacct atcggattgc
     8581 ggatgcggct gtggccatag tagagaaaaa tatgattcgt ccgcttgcgg ctggaaagac
     8641 tcaggtagat gtttatgata aagacaccaa actatctagt ttcgagctga cagttacgga
     8701 gcatcaagca acagtctttg ataccttaag gaacaactgg gaagatattt ctttagccaa
     8761 taaacgctac caatctaacg atactcagat gaaagccttt ctagggcgtt tagatgccgg
     8821 cgtagcttct tctcttaaaa aatgggttga accaacaaat cagggcaaaa cgattttcaa
     8881 cgatattgac tttagtaaat ccagccatct gacaacggtc tatcgccgct tggagcagat
     8941 ggctcaagta gttgagaatc cagactcagc ctattaccac gaccgctcac ttatcgattt
     9001 ggtcagaaaa ggaatgaact ggctttacac caatgtttat aatgaaaata agtcaattga
     9061 tgggaattgg tgggattatg aaattggaac tccgcgtgcg gttgtcaaca ccttgatcta
     9121 catgcatccc tactttagtc aggaggagat tctaacctat accaaaccga tttcaaaatt
     9181 tgtaccagat ccaaccacta tatccgtaaa acattgacca atccagtccc agcagttggc
     9241 ggtaatcaga cggatttgag caaggtggcc atcttggaag gtgctcttcg cgaagatgct
     9301 gaccgtgtga gggctggtgc acaaggtttg acaacgataa tgaaatttgt agataaggga
     9361 gagggcttct acaaggatgg ctcctttatc gaccacacca atgttgccta cacaggggcg
     9421 tatggaaatg tccttattga aggtttttca cagttactac cggttattca gccaacggag
     9481 tttgccctca aggaagaaca gaccaacatt ctttatgaat ggattgaaaa agcctttatg
     9541 ccaatattgg ttcgcggtga actgatggat atgacccgcg gtcgttccat cagtcgggca
     9601 actggtgaat cacatgttca ggctatggag attttaaggt ctttggtccg cattgcagaa
     9661 tcggctcagc ctgagcaaaa aaaacaaact tctctccttt gttaaggcac agctgacctc
     9721 tgataccttc tatgacagct accgcagcct caaatcctat aaggatattg atttggtcaa
     9781 caagctttta gctgataatc aaatccctgc tgaagtagat aaagattata ttgcagcctt
     9841 caacaatatg gataagtttg tttatcgaag cgctcaagaa ggctttacct ttgccttgtc
     9901 tatgtactct tctaaaactc aaaactatga agatatgaac aatgaaaacc gcaagggttg
     9961 gtatacagca gatggcatgg tttacctcta caatgatgat ttgagtcatt acagtaacca
    10021 ctactgggca acagttgacc cgtatcgctt accgggaacg acaacgacca aggacaaacg
    10081 agaagatggc agtggcgagg taactcttgc aagtgacttt gttggagcaa gccagttagg
    10141 caaccgctta gcgacgattg caatgaattt caacaactgg aacaatagtc tgactgctcg
    10201 taaggcttgg attgttctgg gaaataagat tgttttccta ggtactgata tacagcatca
    10261 atctgctcaa ggcgccgtga caacgattga aaatcgtaaa ctcttgaccg gagaaaaata
    10321 tagctattac ataaatggcc agccagttga tttgtccaaa gaagtagtga cagataagac
    10381 tcaatccttt tacatgacca atggcaagga caaccagtcc atcggttacg tcttcttgaa
    10441 ccaactgccg acctatgcca aattagacca gtgaactggc aaatggagtg acatcaacta
    10501 caaccagtcg aaagaagaag tgagcaattc ctttgttagc ctatggcatg aacatgcaca
    10561 gacttcaagt aactatgctt acgtccttgt tccaaaccaa tctatggaaa aagtgaatca
    10621 ggtggctgct agtgtgaaat tgcttcatca agacagggat ttgcaagtgg tatacgacca
    10681 agaacagaat gtctggggcg ttgtgaaata cacggataca gcctacaagc tgacagatga
    10741 tattacctta acagattccg gtttgtatac cattcagaaa gtcgaaggtg gctatcgcat
    10801 cgccttttac aatccgtcta cccgaaccgt aaagaatggc attgagttga caaaggcagg
    10861 ttctagtctg actgttgaga tggagccaac tgcggcttat ccatccactg tctggaaggt
    10921 tactatgcca gaaggttctg ataaacaaac tggaagtgtc gaaaaaacag aaaaagaaga
    10981 aaaacaactc aaggaaaacc aaccaagtcc agaggtgaaa caagtggttc atcatgctgc
    11041 cgaaaaaaca aagtcgagta agccccgtct gccccagaca ggagaagaag caagtttagg
    11101 tcttggtttc ttaggtttgc taaccttggg ggcagtggtg gatttcaagt gtcgcagatc
    11161 gcactcctaa atgaaattcg tgggtgaagg gggagcggga aagaactcga ctagtcaaaa
    11221 aagagttcgt caacaagtct ttatttctag ttgttgagct gaaacagtct atccccagac
    11281 tgtttcactc ccacccccgc atagttgatt agatcagatt cggagtatga aatacgaatt
    11341 gctgaaattt gttttggaac tcctatctcc aacctttagc agtccactga actgttaaag
    11401 ccaatcaatc actgcgctga gatattgata tgaactttga ggagtggatc tgggctttgc
    11461 ccagcctctc ttcttttgga gaagcgatag agaaaggact tgttatgcaa acaatattcg
    11521 gcaaaatagt agccaatcag tcagcagagt cggtcaaaac ctatattctc aatcaacaag
    11581 atgcagctta taaagagctt ctcctttctt gtcaaaattt attaaatgat atttttatct
    11641 ttgaagacaa ttgggatatg gaaccttgtt cagtcgggta tcatcttgct cctcttgact
    11701 ggacagccga ctgccatggg gatgaggaat ggacctttat gctcaatcgg caggaatact
    11761 tgtggaaatt agttttggcc tatctggttg aaaaagattc gcgctacatg gagcaggtta
    11821 aacggtttat ctttagttgg atagaacaag tgacagattg gtatcctaaa agaacgagca
    11881 gtcgcacctt agatacggct atccgctgtc taagctggct caatattctc ccatttttaa
    11941 ttgattgggg cggactaagt gaagctgagc gtagccaact gttagtatcc attcaaaaac
    12001 aattatctta ccttcacagt cattaccgtg ccaaagatac gttgagtaat tggggaattt
    12061 tccagactgg cgcaatgctc ttggcccatg cttatatcgg cgatcaggtg gatttagtag
    12121 agcttcacca ttttgctcgt caggaaatcg aagagcaaat tcaaactcag atattggaag
    12181 atggaactca gtttgagcag tcttttctct accatgtgga agtttataaa ctcttgctag
    12241 gactagcttt cagcttgcca gattatcgaa aacagtggac atctattttg aaaaaaatgg
    12301 cagactatgt cttacagatg acggggccag atggcaaaag tgtggctctt ggcgatagcg
    12361 atgttcattg tacttctgac atcttacaga tgactgcgat tttctttgaa gatggcacct
    12421 acctagtaga taattccaag ctagatttag gcgttctctt cttggtcgga gaaaatggct
    12481 tgcgcatatt tgaacacttg accgctcaat ccagctcgtc agggggacag catttttctg
    12541 aatccggtca cagtattgtc aaagaagtgg acagctattt atgtttcaag gccggtccca
    12601 tgggaagtgc ccacagccac tctgaccaaa atagcttgtg cttttaccac aaaggacaac
    12661 caatcgtaat tgacagcggt cgtttcagct accgtgaatg cgaggagcgc tacttgctta
    12721 aaagcgcttg ggctcacagc acttgtatcc ttgatgacaa tgctccaggg cagataaagg
    12781 gttcatggga atatgacacg tatcctcagt ttattagtca cagttataag ggttttgaac
    12841 actgtcattg gatgcagggc atttatcagg ctcagaccag ccaaggcttg ccttactggc
    12901 ataaacgaca gctccttatg gttggaggcg atttattgct gatagtggat agcgttgatt
    12961 gctcaggcca gcatgagttg atcagtcaat tgattttaga tgaaagagtc aagattggag
    13021 aagagcggtt aaatgatctt cggctatata gtcaaaagga ttttgaaatc cagaaaaccg
    13081 tgcgttctcc tcgatacaac caactagtag agaccaataa actggtcaaa aaagagagtt
    13141 ttcaagatag attagttaca tttactctat tagcagatga agcaattcgt gtcaagcaat
    13201 tgccagttta ccaaacagac tatcatttga tagaaagcgg tttggctttt agctgtcaag
    13261 gaaagggact gaatattctg ttagtggttt ctgataatga tatatgtaag ggagagaaat
    13321 tgcttcaagt ggctggttat aagttgagag gtaagtgctt agtagtggat agggataaga
    13381 gacaagttgt ccgactcaaa aattagaagg gacagaaaaa aatacagtca tttctgtgca
    13441 aaataactga taaagtacgg atagtatgat agaataaagt aactaaagga ggtatcggta
    13501 aggtgtcaga gaagtttacc atcaaagata ttgcagaact ggctcagact tcaaaaacaa
    13561 cagtttcctt ttacttaaat ggtaaatatg aaaagatgtc caaagagaca cgcgaaagaa
    13621 ttgagagagt cattcgcgaa acagactata aacccagcgt tgttgcgcgg agcctaaatt
    13681 caaaaaatac taagttgatt ggagtattga ttggtgatat tacaaataca ttttccaatc
    13741 aaattgtcaa aggtatagaa gaagaagcgc ataagagtgg ctatcaagtt atcatcggaa
    13801 acagcaatta caatcaagaa agcgaagata agtatattga gagtatgctg atgttgggtg
    13861 tagatggttt tattattcag ccgacatcgc attttagaaa atattcgcgc attattgagg
    13921 ataagaaaaa gcatatggtt ttctttgata gtcagcttta cgaacaccgt accagttgga
    13981 ttaagacaaa taattatgat gctgtctatg atgcaactca actatgtgta gaaaatggtt
    14041 atcaaaaatt tattcttatt acagctgaca ttagtcgctt aagtacacgg attgaacgag
    14101 ctacagggtt tatggatgct ctgttagatt gtaaacaaag ttatcaagat ttaacaattg
    14161 cagatgaaaa tacggacata gaggaaatta aatgttttct tcaaggggtg gtaaatcctc
    14221 aggaaaagac cctagtattc gttccgaatt gctgggcgtt acctttagtt tttaatgcta
    14281 tgaaagaact taaatatgac tttcctcagg ttggtctttt ggggtttgac aatactgaat
    14341 ggacaaattt ttcatcccct actatctcta ccattgttca acccgccttt gaagaagggt
    14401 gtcaggcaac aaggatgctg atcaatcaga ttgagggcgg aaaccaagtg ggacgacaac
    14461 aggttttaga ttgcacagtt cattggaaag attctacatt ctaagttaag tcaaatttta
    14521 cttcttagga agaggagcag aacgaagtag aatattctga ttgagagctc actgaaaccc
    14581 tccttgaatc gcctaatata tacaaaaaat aggaattttc ccttaactgg tgggagaatt
    14641 cctattttta tgccaatctc atcgagatga tatattaaca ttatatacga ttttaaactc
    14701 aacagatttc tatagtcttt tagtactagg caatgagctg cagacagtac tggagtgccg
    14761 cacagttgat taggttggat ttagagtgta aaacacgaac aaatccgcca atcaaccact
    14821 gcgctgagat gttgacacga actctaagaa gtggcgctgg gctttttgcc cagcctcacg
    14881 tcaaagataa acaaaatgac tataaaacgg aaaaatagaa atgatatttt tcctaagatc
    14941 tacaacccat ataaataatc atcatctgtc atagcttcca cttcaccaag aagatagccg
    15001 ttaccgactt gggagaagaa gtcgtggtta gatgtaccgg ttgagatacc gttcatgatg
    15061 attgggttga catcatctgc tgaatctggg aagagtggat cttgtcccaa gttcatgagg
    15121 gctttgttgg cgttgtaacg aaggaaagtc aagacttcct cagtccagcc aactgcatca
    15181 tagagggagc gtgtatagcc ctcttcattt tcgtaaagtt ggtagagcag gtcgtacatc
    15241 cagtcgcgaa gtttgtcctg ttcttcctct gataattcat tgaaaccaag ctggaacttg
    15301 tagccaatgt aggtaccgtg cacagattcg tcacggataa tcagtttgat gatttctgca
    15361 acgttggcca gtttgttatt cccaaggtag tagagtggcg tgaagaaacc agagtagaag
    15421 aggaaggttt caaggaatac gctggctact ttcttttcaa gtggtgtacc tgtttcgtag
    15481 atttcattga taatctttgc cttgcgttgc aaatattcgt tgctgttggt ccattcaaag
    15541 atgtcttcaa tctcagactt ggtattcaag gttgagaaga tagaagagta agatttggcg
    15601 tgaacagact ccatgaattg aatattgttg taaacagctt cttcatgggg tgtgcgaatg
    15661 tcattgcgga gggcttggac acctgtttca gattgaaggg tatccaagag ggtcaatccg
    15721 ccaaagacct taccaaccag gtctttttct tcagcagtaa gtttacgcca gtcatccaag
    15781 tcgtttgata aaggaatacg tgtatcgagc cagaattgct cagtcaactt ttcccaagtt
    15841 gacttgtcaa taacatcctc aatggcgttc cagtttatgg ctttgtagta ggtttccata
    15901 ttactttctt tcgttttatc aataattatt ttttgcgttt tccgactaag tattttcctg
    15961 cttcaggact accgtggcgt aatccatccg cagctagtcg gtcgctcgtt tttttgagct
    16021 tattattttc ttttttagtt tgtgaataag ctttttttag tacgttattt tctcttttta
    16081 attttttatt ttcttgtttt gttttaccaa atccaaacat aaaaaacctc cagaaatatt
    16141 gaatagcttt attttagtct gtaaatcaga ttacacaact ttcacattgg tttgcgccga
    16201 cttcttcgcc gtcatcggta aaggtacgga tgtagtagat agacttgata cctttgttga
    16261 aggcgtagtt acgaaggata gagaggtcac gtgtagtttg tttgttctct tttttccatt
    16321 catagagttc ttttgggagc tcgctgcgga ggaagagggt gagggacaaa ccttggtcaa
    16381 cgtgttctgt tgcggcagca tagacatcaa tgaccttgcg catatccata tcgtaggcag
    16441 atttatagaa tggaatggtt tctgttgtca agccagctgc tggatagtag attttaccga
    16501 ttttcttctc ttggcgttct tcaatccgtt gtgtgattgg gtgaattgaa gcagaaacgt
    16561 cgttgatata agagatagaa ccgttaggtg caacagctag acggttttga tgatagagac
    16621 catctgccat taccttttca cgaagctccg cccaatcttg tccacttgga atgaaaattc
    16681 cttcaaatag ttctttgaca cggtcagatt gtggttggta gtctccggtc acgtatttat
    16741 cgaaataagt gccgtctgcg tattttgatt tgtcaaaatt atggaaggtt gccttgcgtt
    16801 cacgggcaat gttatttgat tctaccaaag tccagtagtt gaggagcatg aagtagatgt
    16861 tggtaaattc tacagcagtt tttgaaccgt aatcaatcaa gttctgagcc aagtaagaat
    16921 gaagtcccat agctccaaga ccgattgaat gcgcttgact gtttcctgct tcaatagatg
    16981 gtacagctga aatgtgtgaa tgatctgtga cataagtcaa agcacgagtc atggtacgga
    17041 cagaacgtcc aaaatcaggc gacttcatca agttaacgat attggttgaa ccgaggttac
    17101 atgaaacatc agtacccatg ctcaagtatt cttgcgaatc attaagaatg cttggtgttt
    17161 gaacttgaag gatttccgaa cagaggtttg acatgataat cttgccgtca acagggttgc
    17221 tacggttagc tgtatcgatg ttgataacgt atggatagcc agactcttgt tggagtttgg
    17281 aaatttctgt ttccaagtca cgtgccttga tttttgtctt acggatacgt gggtttgcta
    17341 ccaactcgtc gtatttttct gtgatgtcaa ggtagctata agggacaccg tattccaact
    17401 caactgagta tgggctgaag aggtacatat cttcgttttt acgtgccaat tcgtagaatt
    17461 tatcaggaac agtaataccg agtgataagg tcttcacgcg aactttctca tcggcatttt
    17521 ctttcttagt cgaaaggaag gaaataatat ctgggtggaa aacatcaaga taaacgacac
    17581 cagccccttg gcgttgccca agctggttag aataggagaa gctgtcttcg aagagtttca
    17641 taacaggaac aaccccagaa gctgccccct catagccctt gattggagca cctgcctcac
    17701 gcaagttgct aagggaaata ccaacaccac caccgatacg ggacaattgc agagcagagt
    17761 tgatagaacg tccgatcgag ttcatatcgt cagtgacttg aatgaggaaa cacgatacca
    17821 actcaccacg acgggcacgg cctgcgttga ggaaagacgg tgttgctggc tggtaacgaa
    17881 gatgaatcat ttcgttggcc aggtttagtg ctaattcttc gtcgccctca gcaaaataca
    17941 aggcgttgaa gagaacgcga tcttccatac tttccaagta gtaagccccg tcgttggttt
    18001 taagggcata ctggttgtag aacttgtaag cagccatgaa agacttgaag cggaaatttt
    18061 ggtctttcaa gaattgatcg attttgatga taaattctgg actgtattgg tccaaaaact
    18121 ctttttcgag gtaattttct tctaatagat aagcaatctt gtctaaaata ctatcaaatt
    18181 gcttggtatt tgggaggacg ttttctgtaa agaaggcctt aaccgcttct tggtccttgt
    18241 ggagaggaat ttgtccattg acaggacggt tgatttcgtt atttaaacgg aagtaggaca
    18301 catcgcctag ctcttttaaa ctcatagtcg caatctcttt ctataaacag tagggagtta
    18361 aaccaaggct tttagttttc ctggttgaaa acctgagaaa acatcatttt cagtttcgat
    18421 aacaggtgca gctgagaaac cgagaccttg tacgtgatcg ataaattcag gctgttcatc
    18481 tagattgatt tctttataat ctacactatg ttggtccaag aatttcttgg tcattttaca
    18541 ctgtacacaa tcattttttg aatagatcgt taccattcaa tttctccttt gtccatgagg
    18601 gattaataaa aaatcccaat tttgttacca atctaggata caagatttta aggttaaagt
    18661 caagaaggaa gtttatttaa aatcacaaaa tatagtgcac aatattttca taagacacca
    18721 tatattgtac atccgtccaa tgctgccaag tcgaaaaata gcgtttacat agctgtttct
    18781 atttagtttg ataaccctaa caatctctcg gtaaagtata aatcagcttt tttacaaatg
    18841 tcataatatt ttgaaggaaa taaacgatgt tacaaaatat aacatttatg gttatacatg
    18901 tattgaatat atattacctt ttgtactata ctattcaata atgtcgaaag aggttataaa
    18961 atatggaaaa aacacagaga aagcgcttgt tttataaagg ggaagaatat tcatattatg
    19021 cattggagtc gatttcaatg gaagaaaaag tggatattca ttcacttccc tatactattc
    19081 gtattttatt agagagtctt ttaagaaaag aagatggtgt ggatgttaca aaaaatcaca
    19141 taatggagtt gcttcattat caggctgcct ctcctaaagg ggaaattcct tttaaaccta
    19201 gtcgtgttat tttgcaagat tttacaggtg ttcctgttgt ggtagattta gcctccatgc
    19261 gtgatgcggt ggtgaaagca ggtggaaacc ctgaattgat taacccagaa attccagtgg
    19321 atttagtcat cgaccactct gttcaagttg atttttttgg gactgaagat gctctggaga
    19381 aaaatattgc cttagagttc gaaagaaata atgaacgcta tgaatttctg aaatgggcag
    19441 agaattcctt tgaaaattat cgcgctgtgc ctccagcaac aggaattatc catcaggtaa
    19501 acattgaatt tctaagcgat gttattatca acaaggatgg tttgctttat ccagattcta
    19561 tgtttggtac agacagtcat acgaccatga ttaatggtat tggtgtactt ggttggggtg
    19621 taggtggtat tgaggcggaa gctgcaatgt tgggtgaagc atcttatttt cccgttcctg
    19681 aggtgattgg tgttcgccta gatgggcaat tgcctaaggt tgccactgca acggatttgg
    19741 cgcttaaggt cactcaactt ctacgtcagg aaaatgtagt tgggaagttt gtcgaatttt
    19801 ttggaccagg tttatcttct cttacattag cggatcgagc aactgtttcc aatatggctc
    19861 cagaatacgg tgcgacttgt ggctatttcc cgatcgatgg agaaacttta cattatatga
    19921 gattgaccaa ccgttcggag gagcacgtgg agttgacaga agcctatgct aaggctaatt
    19981 atttattcta tgatgctgaa cgttttccgt cttatagcaa ggttttagaa ttggatttat
    20041 cgacagtagt cccatctatt tctggtccta aaagaccaca ggatttgata gaattaacag
    20101 atgcaaaagc agagtttcag gctagtttaa tacgtgaagt aggcgtgcgt ggatttggtt
    20161 tggaggaagc agagttagat aaaacagcct cggttaagta tgttgaagga gatgagcaaa
    20221 ttcaaacagg tcatgttgct attgcggcga ttacctcgtg tacaaatacc tccaatccgt
    20281 atgtcctttt ggcggcagga ttactggcga aaaatgcggt agaaaaaggt ttggcagttt
    20341 ctaagacggt caagacgtca ttggcaccag gctcaaaagt agtgactggc tatttgaaaa
    20401 aatcaggttt gcagacctat ctagatacct tagggttcaa tttggttggt tatggttgta
    20461 caacttgtat cggtaactca ggtgatctgt gtcctgaagt ggcggaggcg attaaggaag
    20521 aagatttatt ggtttctgcg gtattatctg gaaatcgtaa ctttgaagga cggattaatc
    20581 cgttggtaaa agctaatttc ttagcgagtc caccgattgt agttgcctat gctattgcgg
    20641 gaaatatgaa tgtagattta acaagggatc cgctggggta tgatgagaag caacaagctg
    20701 tctaccttgc ggacattatg ccaagtcgtg aggaggtaga cgactacatt gagcgttatg
    20761 tgactcgtga cctttataag gaagaatacc aacaggtatt tacagatagt caggcttgga
    20821 atgcgattga aacaaaaata aataagaatt acaattggaa ttcatcttct acctatattc
    20881 aaaatccgcc ctattttgac aacatgcagg cagatttatc cataaaacca ctggaaaatt
    20941 tatctgtttt ggctaaattt ggcgattctg taacgacaga tcatatttcc ccggcaggga
    21001 atattgcacg attgagtcca gccgctcgtt atctcgaaga gaatggcatt gtttataagg
    21061 attttaattc ttatggaagt cgtcgtggaa atcacgaagt catgatacgt gggacttttg
    21121 caaatattcg tataaagaat gagctggcag atggaaaaat tggtggttgg acaagagttg
    21181 gcgaagagat tcttcctatc tatgatgcgg ctatgagata taaggaagtt ggtgtcggta
    21241 gtattgttat tgctggtaaa gactatggga tggggtcaag ccgtgactgg gcagcgaaag
    21301 gttcaagttt acttggtgtg aaggctgttc ttgctgagtc atttgagcgg attcaccgtt
    21361 caaacttagt gatgatgggt gttcttcctt tacaattttt agaaggtcag tcggcagaaa
    21421 gtcttggctt gactggacat gaaagctata caattgattt gccagaagat gtcggtgttg
    21481 gtcaaattgt aacagtccat gcgcaaacag acgatgttac aaaggagttt caagctctgg
    21541 tgcggtttga tgcagaagcg gatattcgtt attatcgcca cggaggtatt ttacctatgg
    21601 tagtaagaaa gaaattagga ggaaaggtat gacagaaacg aatgggttaa aagatgcgat
    21661 tgcctgtgat acgcgaatca gtgcaattga aaatgaccgc ttgtcctatg cagggtatga
    21721 catcgctgaa ctgatggaga ataacgcttc ttttgaggaa gtcatctatc ttctgtggaa
    21781 cctgcatttg ccaactcaga ttgaattaaa ttattttgag aaaagcctgc gaaaagaata
    21841 tgcgatttca gatgcggtag agcaatgtat tctgattcaa tcacggcgac atttgcatcc
    21901 aatgagcgtg ttgcgttcga cagtatctct ccttggagta tataatgtac acgctgaaga
    21961 gaattcgtta gaggctttgt atgaacaatc tattcagatt atggccaagg ttccgacgat
    22021 tattgcaaca tttgctcggt tgagacgcgg attggttcca attgaaccgc ggtctgatct
    22081 gggttttgcg gcgaattttc tttatatgct gaatggtgag gagccgagtg atttacaaat
    22141 caaagcgttt aacaaagctt tggtgcttca tgctgatcat gaattgaatg catctacttt
    22201 tgctgcgcgt gtcacggcat caacgttaac ggatttatat tcttgtgtca ccacggcaat
    22261 tgggactctg aaaggctcat tgcatggtgg tgcaaatgaa cgagtgtttg acatgttgtt
    22321 ggctattcgt gagagtggtg ataccgagag atatttgcag aagaagctgg attcgaagga
    22381 aaaaattatg ggatttggcc atcgagtcta taaaacggtt gatcctcgcc aagagtattt
    22441 gaaggagatg gcgcgtgatt tgacattcgg aacagacgat gaagcgtttt atagattgtc
    22501 agaggaagta gaaagcttta ttaaaaccaa aaaaggttta attccaaacg tagattttta
    22561 ttcggcgaca gtttaccatg tgctaggtat tgatagtgat atttttacat tgatttttgc
    22621 aatgagccgt atggcggggt ggattgcaca tgtccaggaa caacggaaaa ataataaatt
    22681 gattcgtccg cgctcttcct acttaggtgg taggaatttg gtttacatcc cgattggaaa
    22741 gaggtaaata tggcagaaaa aatcctaatg agagagggac ggttaattgt cccagattgt
    22801 cccgttattc cctatattga aggagatggt attggcaggg atatttggtc agtcagtcaa
    22861 aaagttattg atgctgcagt gaaaaaagcc tatgcaggtc aacgttctat tcagtggagg
    22921 gaggtttttg caggagaaaa ggcttatgaa ttaatgggaa cttctttgcc gaatgagaca
    22981 ctggaaataa ttcgtgagca tttagttgca atcaaaggtc ccttggggac gccgattggg
    23041 aaaggtcatc gttctcttaa tgttgcactt cgtcaagaat tagatttgta tgcctgtgtg
    23101 cgtccgattc gctattttaa gggagtgcca agtccgctga aagagcctga aaagacggat
    23161 attactattt ttcgtgaaaa tacagaagat atttatgcag gtattgaatg ggaggctggt
    23221 tcagatgaag ttgccaaagt catttccttt ctgcaagaag aaatgggagt ggtaaatatc
    23281 cgttttccag aatcttcaag tattggtatc aaaccgattt cggaagaagg gagtaaacgc
    23341 ctcattcgct ctgcaataga atatgcccta gaacatcaat tgaagatggt gaccttagtt
    23401 cataagggaa atattcaaaa gtttacagaa ggtggcttcc gcaagtgggg ttatgaattg
    23461 gcgaaagaag aatttgctac agaacttgca gaggggactt tggtagtaaa tgacattatt
    23521 gcggataact ttctgcagca gattttattg gcgccggaaa acttccaggt ggttgctctt
    23581 acaaatctaa atggagatta tgcatcagat gctcttgcgg ctcaggtcgg aggaataggc
    23641 atctcaccgg gtgctaacat taattatcag acaggtcatg ctatctttga agcgacacat
    23701 ggaactgctc ctgatattgc aggaaaggat ttggctaatc catgttctct cttgctttcg
    23761 gcttgtatga tgttggaata tattggctgg aaagaagcgg ctgttttaat tattcaggcc
    23821 ttggaagacg cttttataaa taaaaatgtt acgcttgatt ttgctaaaat tttggacgtt
    23881 gctcatcaat ctactagtca attttcagaa gttctaatag attctattta atgaagaaaa
    23941 agtaaaatga acctctcttt ttatgacgga aacatgaaag aaaggtaaaa aaatcttgaa
    24001 aatgatttca aaaagtggta taatgtcctt tgtaagggtt atcacaaata actcgcaatt
    24061 ttgtaaaaat aaaggagaat ccaaatatgg cttcaaaaga cttccacatt gtggcagaaa
    24121 caggtatcca cgcacgtcca gcaactttgc ttgtgcaaac agctagtaaa tttgcttcag
    24181 acatcacttt gaactacaaa gaaaagtctg ttaaccttaa atctatcatg ggtgttatga
    24241 gtcttggtgt tggtcaaggc gctgacgtaa caatctctgc tgaaggtgct gatgctgacg
    24301 acgcaatcgc agctatcact gaaacaatgg aaaaagaagg attggcataa gaatatgaca
    24361 gaaatgctta aaggaatcgc agcatcagat ggtgttgctg ttgctaaggc atatctactc
    24421 gttcagccag atttgtcctt cgaaactgtt acagttgaag atacaaatgc agaggaagct
    24481 cgtttggatg ctgctctaga agcatctcaa aacgagcttt ctgttattcg tgagaacgca
    24541 gtagctagcc taggtgaaga ggccgcagcc gtatttgatg cacacttgat ggttcttgct
    24601 gatccagaaa tgattggtca gattaaggaa acaattcgtg cgaagaaaac aaacgctgag
    24661 actggtttga aagaagttac ggatatgttt atcgctatct ttgaaggtat ggaagataac
    24721 ccatacatgc aagagcgtgc cgcagatatt cgtgacgtag ccaaacgtgt attggcacac
    24781 ttgcttggtg ttcgcttgcc aaacccagca actatcgacg aagagtcaat cgttatcgca
    24841 catgacttga caccttcaga tacagcgcaa ttaaacaaac agttggtaaa agctttcgta
    24901 acgaacattg gtggtcgtac aagtcactca gctatcatgg ctcgtacact tgaaattgct
    24961 gctgttttgg ggacaaataa cattactgaa atcgttaaag acggtgatgt attggctgtt
    25021 aacggtatca caggtgacgt agtgattaac ccttctgaag aagtgattgc agaatttaaa
    25081 gcagctggtg aagcttatgc taaacaaaaa gctgaatggg ctcttttgaa agatgctcaa
    25141 acagttacag ctgacggcaa acactttgaa ttggcagcaa atattggtac accaaaagac
    25201 gttgaaggtg taaatgataa cggtgcagaa gcagttggtc tttaccgtac agagttcttg
    25261 tatatggact cacaagactt cccaactgaa gacgagcaat atgaagctta caaggctgtt
    25321 cttgaaggta tgaatggcaa gcctgttgtg gttcgtacaa tggatattgg tggtgataag
    25381 gaacttcctt acttcgatct tccacacgaa atgaacccat tccttggttt ccgtgccctt
    25441 cgtatctcta tctctgagac tggtaaccaa atgttccgca ctcagttgcg tgcccttctt
    25501 cgttcatcag tacatggtaa acttcgtatc atgttcccaa tggttgcctt gttgactgaa
    25561 ttccgtgcag caaaagcaat ccttgatgaa gaaaaagcaa acttgttggc tgaaggtgta
    25621 gcagttgcgg atgatatcca agttggtatc atgattgaaa tccctgcagc agcaatgctt
    25681 gcagaccaat ttgccaaaga agttgacttc ttctcaatcg gtacgaacga ccttatccag
    25741 tacacaatgg ctgcagaccg tatgaatgaa caagtttcat acctctacca accatataac
    25801 ccatcaatcc ttcgcttgat taacaatgtt atcaaggctg cacacgcaga aggtaaatgg
    25861 gctggtatgt gtggtgagat ggctggtgat caacaagctg ttccacttct tgtaggtatg
    25921 ggcttggatg agttctctat gagtgcaaca tctgtacttc gtacacgtag ccttatgaag
    25981 aaacttgata cagctaagat ggaagaatat gctcaccgtg ccttgacaga atgtgcaacg
    26041 gcagaagaag ttcttgaact tcaaaaagag tatgttgatt tcgattaatc gttgaaaaaa
    26101 gcagggaatt gaatccttgc ttttttactg ttcacaaaaa gacttgtcgg agcaagtctt
    26161 tttgtgtgct tagtttttct gataaaattt attgtgttgg tagatagggt caaaggtaag
    26221 attgatgcct aatttacgaa ggacactctt gtcttcatca gataggataa cagtcgagtg
    26281 ggcttcgcta ccatttaatt ggcctaattc tttcatggca cgtgcagcaa gagggctatc
    26341 ttgtgcagtg atggcaaggg cgttaagaat ctcacttgca tcgagtcgtg tattggtctt
    26401 atccagataa tctgccttca attcttgaat tggacggatg tagtttggtt cgatgagaag
    26461 tgtttcatca tcgatgttag caatttgctt gatggcattg agaaggacag ttgcagttgg
    26521 cttgaggagg tcggatgtct tacctgttac aatctctcca gttggcaact gaatagcaag
    26581 ggcagggcta gttgtcagct ctgctttttc gcgcgcagcg ataacaacct tacgatctgc
    26641 tggcgtcaca ccgacttcat tcatgaggag ttcaatcttt ttaactgctt gctcgctcac
    26701 ccgctctgct ttgaaatcaa ccaaggtctg gtagtagcgg cggatgattt cttgcttgga
    26761 tgcttcgatc gcagcctctt cgtccacgat ggaatagccc accatgttaa cgcccatgtc
    26821 tgtcggtgag gcgtatggtg atttgttcaa aatacgttca aaggtacggt tgaggacagg
    26881 gaagacctcg atgtcacggt tgtagttgac cgcagttttg ccgtaagttt gcagatggaa
    26941 ggggtcaatc atgttgaggt cgtccaggtc ggcagttgct gcttcatagg ccaagttaac
    27001 gggatggtgg agtggtaagt tccacactgg gaaggtttca aacttggcat agcctgatgt
    27061 tactccatgc aattggtcgt ggtaaagttg ggagatacag gtcgccaatt tacctgaacc
    27121 aggtccaggt gcggtgacaa cgacgagatt gcgactagtt tcaatgtagt catttttgcc
    27181 cataccttct ggtgaaatga tgtggtcgat atcagaagga taacccttga ttggatagtg
    27241 gagataggac ttgataccat gtttttccaa ctgtttgcgg aaggcgtctg cggctggttg
    27301 gttgcggtat tgggtaatga ccacagaacc aacataaata tcaatatcat tgaaggtgtc
    27361 aatcaagcgg aagacttctt ggtcataaga aatacccaag tcaccacgtg ccttagaatg
    27421 ttcgatgttg cttgcattga tggcgatgac gatttctact tggtctttta actcttggag
    27481 gagtttgatt ttgttatctg gttcatagcc aggtaaaaca cgggctgcgt ggaaatcttc
    27541 caacattttt ccgccaaatt ccatatagag cttgccttca aattgggcaa tacgctctaa
    27601 aatatggtca cgttgcaaat tcaaatattt agttgaatca aatgcgattt ttttcataaa
    27661 tatgtcctcc aaatgtgtat taatctctgg gaaaacaaaa aatagctccc taaaactagg
    27721 gagccttttc tccgacctct caaaagaggt gcccgaacaa tactataaca aactgtgcta
    27781 atcttgtcaa gaaaaagtca gacagaagaa aaattaaaca agtgtttaaa aaaat
//
LOCUS       DBNFCO010000019        27827 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.019, whole genome shotgun sequence.
ACCESSION   DBNFCO010000019 DBNFCO010000000
VERSION     DBNFCO010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 27827)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27827)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27827
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.019"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(80..1249)
                     /locus_tag="AC1PIV_000706"
     CDS             complement(80..1249)
                     /locus_tag="AC1PIV_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HIP6611745.1"
                     /translation="MFRLAKEELEKLGAIITATEIYQQPGLWKEAYQLYFDQLEKIES
                     FLKSIKEKHDFVHVVFTGAGTSDFVGQSIANYLNQVNDLKHIRFSAIGTVELVSRPHD
                     YLQADVPTVLVSFARSGNSPESVAAVEVAKQLVDKLYQVTITCAPEGKLALAAEGDAE
                     NLLLLQPAGSNDKGFAMTGSYSCMALTALLVFSSASQEEKAAWVEIIARLGQDVLDRE
                     DYVQDLINLDFERVIYLGSGGFYGLAHEAQLKILELTAGKIATMYESPLGFRHGPKSF
                     INEKTLIFLFASNDAYTRQYDVDLLNEVHGDGIAERIVALSADKLVGTEAANFVLAEG
                     GADLPDVFLTFPYILFAQTVSIMAAIKCNNLPDTPSPTGTVNRVVQGVIIHPLEK"
     gene            1516..1815
                     /locus_tag="AC1PIV_000707"
     CDS             1516..1815
                     /locus_tag="AC1PIV_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HIP6611746.1"
                     /translation="MMNMQNMMRQAQKLQKQMEKSQAELAATQFTGSSVQDLVTATFT
                     GDKKLVSIDFKADVVDADDLETLQEMTIQAVNAALTKVDEATQKKLGAFAGKLPF"
     gene            complement(1859..3619)
                     /locus_tag="AC1PIV_000708"
     CDS             complement(1859..3619)
                     /locus_tag="AC1PIV_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HIP6611747.1"
                     /translation="MKKIQREFQKIYYNLDKILLLFFTLFTFMEFVWIPLNSWISEGL
                     LAMTGHAYLSPTNLLSVFAENLLVTGLFILLFFVNIAIAYLELALLFTGVWQLLDEKV
                     KHLTDYLRDVRDSMVAIIRHSSLPKVLFLLFYSVILLPFLRRVLNIYYFNKIVVPQFI
                     VDYLSNTVWLGILILIFLLLFFWLAARFMYALPNIYFEHRGVKESIAYSWEKTRGRKQ
                     IGSLFRLIWLVTFPVLLFTGVGGLFYLVQLLAEHFVPSASYWLAVVCYALLKLAYYGV
                     VALFMMGFVSLLTGKQLPIYRRKRLRHHLRLAILLVSGLVFGTQGALALYFPFDTLPV
                     TISHRGVDDGNAVQNSIEALEKTSQLKPDYIEMDVQETKDGQFIVMHDTDLLALTGNP
                     GGTHDYTLAELTGMTASENGMAAPVPSFDEYLEKADELGQKLLVEIKVTKADSPKLTQ
                     NFLKKYGQRLIAKGHQMQSLDYRTIIEIKQYSEKLVSFFILPFNSIYPTTVADGYTME
                     YTSLDQNFMTKSWIRGKSVYAWTPNEEESMTKMLLLQVDGIITDNMTDLQSLMEEMKE
                     NRRYPDLFFQQFQSLIYNFE"
     gene            complement(3810..4736)
                     /locus_tag="AC1PIV_000709"
     CDS             complement(3810..4736)
                     /locus_tag="AC1PIV_000709"
                     /EC_number="2.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012774920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HIP6611748.1"
                     /translation="MRQTKEMRLVYSDFLAQVGQEDTTIAAIEADLSSSMATNKLSSV
                     LGGRYVNVGIMEQEMVGVAAGLSLLGYKPYIHTFGPFASRRVYDQVFISLAYAQLNAT
                     IVGSDAGVSAEMNGGTHMPFEELGLMRLIPKARVYEVSDDVLFQAVLKETIKVDGLKY
                     IRTIRKAPTPIYQGGEDFSKGYCVLRQGEDMTLLASGIMVEQALKAADQLEAQGVSVQ
                     VIDLFRIKPIHEDISALLSGRPVLTVENHNRIGGLGSSICELMATDLTTPVHRIGIEE
                     SFGQVGQQAYLMDVYGLTAEYIVKQAQLMLQQ"
     gene            complement(4733..5581)
                     /locus_tag="AC1PIV_000710"
     CDS             complement(4733..5581)
                     /locus_tag="AC1PIV_000710"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HIP6611749.1"
                     /translation="MTSGTADLKRFAKEIRYHTLATLNQLGFGHYGGSLSIVEVLAAL
                     YGEILDIRVQNFSSKERDHFILSKGHAGPALYSTLYLKGFFDRDFLLSLNQNGTHLPS
                     HPDRNLTPGVDMTTGSLGQGMSVATGVAYGKKIEQSPYYTYTLVGDGELNEGQCWEAA
                     QFAAHHELSKMILFVDDNKKQLDGRTHDICQTFDFVEKFQAFGWESVRVNGADIDAII
                     NAILTMKSSKSPQPKCIVLDTTKGQGVTFLEELESNHHLRLSGQLREDLEQVTLVLAR
                     ELEVTE"
     gene            complement(5583..6929)
                     /locus_tag="AC1PIV_000711"
     CDS             complement(5583..6929)
                     /locus_tag="AC1PIV_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HIP6611750.1"
                     /translation="MILDFLIDIAKTPAILVALIAILGLALQKKPAADLVKGGLKTFV
                     GFIVVGGGANIIVGSLEPFGQMFEQAFNLKGVVPNNEAIVAMALDKYGTATSLIMLLG
                     MVFNIAIARFTRFKYIFLTGHHTLYMACMIAVIMSVAGFTSVGLIVMGGLALGLIMTL
                     SPAFVQKYMIQLTGNDHVALGHFSALGYWLSGVVGGLVGDKSKSTEDINFPKGLAFLR
                     DSTVSIAISMSLIYMIVALFAGGDYIKENLSGGTNSMIYALTLGGTFAAGVFVILSGV
                     RLILAEIVPAFKGISEKLVPNSKPALDCPVVYPYAPNAVLIGFISSFAGGIVSMIILA
                     LTGGVVILPGVVPHFFCGATAGVMGNASGGVRGAVCGAFMQGVLISFLPVFLLPVLGD
                     LGFAGSTFSDADFGLSGIFLGVLAKNGGILTVSVGIFAVLALMLGLSLVKKEQKEG"
     gene            complement(6983..7267)
                     /locus_tag="AC1PIV_000712"
     CDS             complement(6983..7267)
                     /locus_tag="AC1PIV_000712"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HIP6611751.1"
                     /translation="MLRIGTACGSGLGSSFMVQMNIESILRDLGVSDVHVEHYDLGGA
                     NPSEADVWIVGRDLADSATHLGDVRILNSIIDMNELRELVTAICQEKGLV"
     gene            complement(7269..9311)
                     /locus_tag="AC1PIV_000713"
     CDS             complement(7269..9311)
                     /locus_tag="AC1PIV_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HIP6611752.1"
                     /translation="MVDNRTMAILMELFATRKESLYELSIQTGIEKEQLHSNLELVNQ
                     LLQEHSFPQIQYKDSEFVISTELYNQKESVFSLFRNRQIYLSQEERQLLIYLYTFIRK
                     EFVSNVHYQELLSVSRNTTLTDIKNVKELCLDFQVRLEYTRAKGYHLIGREEDKHRLA
                     LYALSNCLQSSIGVWALDYILKSWGEENPIEELKIVSQQACNYYKVSALEERLDEYLY
                     FLIFLFIRQARVGNRINWNFEGKGGFVKDFLQRLWKLLRLKSTSTLELNAATQEYLSH
                     LLQGCLEGESGEKDDLFYHLTVEIVEEMERLSLITFEHRSEMIEGLQRHLIPAYYRLT
                     SRLVNVNSYTETIKEEHADLFYLVKKALRPLEEHLGFTIPDSEVSYFVIHFGGYIEAG
                     QQRSYRYRALVVCPNGVSSSLIVKENLRQLFPNIYFADTHSLQDWKMLDMTDYDMVFG
                     TIKLNIELPFFLVSQLMTSNHKKELFHLVNQHFPNAAYFPIEIEQLLSLVGKHATIHQ
                     EQALKYELVQFLNQRSHEQRGRSPMLEELITKETFQWSEEVLDWQKAVALAARPLVDK
                     GAIETRYIDAMIAKVEEFGPFIDLGKGIAIPHARPEDGVNEVGMSMLVLDKPVYLLDD
                     PSHEIRLFICIAAVDNQTHLRALSHLTKILREEENIQQLVGTKEFADVQHLLKEEQ"
     gene            complement(9579..10073)
                     /locus_tag="AC1PIV_000714"
     CDS             complement(9579..10073)
                     /locus_tag="AC1PIV_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019783378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HIP6611753.1"
                     /translation="MGIEKTVSELAEILGVSRQAMNNRVKSLPEEFVDKNDKGVTVVN
                     RAGLIKLEEIYKTTIFEDEPISDEVKHRELMEILVDEKNAEIIRLYSQLKAKDKQLAE
                     KDEQLKVKDVQIAEKDKQLDQQQQLTLKAMADKEVLKLELDEVKAQAEEVQAKGFFAR
                     LFGK"
     gene            complement(10243..11643)
                     /locus_tag="AC1PIV_000715"
     CDS             complement(10243..11643)
                     /locus_tag="AC1PIV_000715"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HIP6611754.1"
                     /translation="MVTEQREYRFPEGFLWGSSTSGPQSEGSVAGDGKGWNNWDYWYS
                     QEPELFHQQIGPEQTSTFYEHFQSDLDLLVETCHSIFRTSIQWSRLIPEGIGEVNPQA
                     VEFYRAVFAGIRERGIKLLVNLYHFDLPYVLQEKGGWENKEIVWAYEAYARQCFSLFG
                     DLVDHWITFNEPIVPVECGYLGSYHYPCKVDAKAAVVVAYHTQLASSLAVRACHQLHP
                     DHKISIVLNLTPAYPRSQSPEDLQAARIAELFQTRSFLDPSVLGQYPRELVDILEKHG
                     LRPETTEEELTIIKENRVDFLGVNYYQPLRVQAPSEDGWNGEPTFLSQYFQPYDKPDK
                     KINPHRGWEIYEEGLYDIAKNIQENYGNIEWLVTENGMGVEGEGVFEENGMIQDDYRI
                     HFMEDHLIQLHRGIDEGANCKGYMVWTFIDCWSWLNTYKNRYGLVSLDLQTQKRTVKK
                     SGYWFKQVSAKNGFIR"
     gene            11881..13056
                     /locus_tag="AC1PIV_000716"
     CDS             11881..13056
                     /locus_tag="AC1PIV_000716"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HIP6611755.1"
                     /translation="MNTVDTIIIGAGPAGMMAAISSSFYGKKTLLLEKNKRLGKKLSG
                     TGGGRCNVTNNGTLEDLLAGIPGNGRFLYSVFSQFDNHDIMNFFQENGVKLKVEDHGR
                     VFPTTDRSQTIIKCLEMKMLENGVDIRTGTEVVSVRKMDDLFHVKTSEEVFTAPQLIV
                     TTGGKTYPSTGSTGFGHDIARHFKLEVTEIEAAESPVLTDFPHKKLQGISLDDVTLTY
                     GKHVITHDLLFTHFGLSGPAALRLSSFVKGGETAFLDVLPTHSDQDLFEHLEKNREKS
                     VKNTLSELMPDRLADFFAENYDSKVKQVSQKDLTELVTLLKVLPIKITGKMSLAKSFV
                     TKGGVDLKEINPKTLESKKVPGLHFAGEVLDINAHTGGFNITYCLATGWVAGSSYSS"
     gene            13412..14110
                     /locus_tag="AC1PIV_000717"
     CDS             13412..14110
                     /locus_tag="AC1PIV_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HIP6611756.1"
                     /translation="MQLKLSSISKKFDHKSILEDASFQFEQGKIYGLLGRNGAGKTTL
                     FNCIARNLTLDNGSIQFVKGEETLDYDNTDIGFTQTYPQLPAFMTAYEFVRFYMDIHK
                     DKLKSPRSPEEWLNLVGIGEEDQHRLLKDFSHGMQNKVQLLLSLIVQPPVLLLDEPLT
                     SFDPVAAHEFKQLIREAKKDSVIIFSTHILQLAQDLCDEIVLLHHQELQAVPSDKLHD
                     PDFEQEVVALLTAD"
     gene            14120..15742
                     /locus_tag="AC1PIV_000718"
     CDS             14120..15742
                     /locus_tag="AC1PIV_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611757.1"
                     /translation="MKTILRYSWYQEKYNLHRSVNGFFYYLRKLPLVGKCIPESIFKS
                     YSFKSSLFLVLHILSIPSRFLIKGFWLLFHFYHASFWMNMLVNGELTFWKILPNTWLL
                     GFMFWLLFVGLSYRLGKSLDPVISKADREFMQNFSLSQSSFLQSQLFIEPILTTIYYL
                     PASTIFCMITKEWLVFPIGLMTVLAGHLAGHALNRLLFERRIFSRRNSWHAWLWIAFV
                     FVLYVLAIVFRNQLSSGMLVPILLVQPFLIWFSYGYLKQQTNHLDYLSYCMDESLQMD
                     KKLFEMTKGNEYTRQGLQMQAKLNAKTGKDLSHLSGMTYLNALLFDRYKKVLYKKVQN
                     WVLAVVVILAALEGIRYFLDPFTFTEAYLLQFLPLSFMIMYVASSGKVVAQMVFVNCD
                     ISMLHYPFYREAKTIIAGFNYRFLQTCKLNLIFATSLFLAIMVLGRFAFSLETILLTA
                     LLLISLTALFSFHDLFIYYILQPFTNDMDVVNPLYKFLSGALYWVAYLNTRINVGSHT
                     YILLVSLAMIAYVSIGYWILLKKAPQTFRLKA"
     gene            complement(15962..16522)
                     /locus_tag="AC1PIV_000719"
     CDS             complement(15962..16522)
                     /locus_tag="AC1PIV_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HIP6611758.1"
                     /translation="MTIKYPDGTIDLLSPVEVVKQADKTAPTVANDGKGNIVIVPSEK
                     AVELVVSYVDNNGKSQTVVVTKGTDGLWTASNTVVIVDPVTGQVIVPGSVIKPGTVVT
                     AYSKDEVGNSSDSAEAEVVAVDENNSAAGVKVKSVTTNANNVEKKAKQLPNTGEEANS
                     ATSLGLVALGLGLALLAAKRRRDEEA"
     gene            complement(16556..17119)
                     /locus_tag="AC1PIV_000720"
     CDS             complement(16556..17119)
                     /locus_tag="AC1PIV_000720"
                     /inference="COORDINATES: protein motif:HMM:NF019202.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HIP6611759.1"
                     /translation="MAQDVLDAAKQDAKNKIAKESDAAKSAIDANPNLTDAEKESAKK
                     AVDADAKAATDAIDASTSPVEAQSAEDKGVGAIAKDILDAAKQDAKNKIAKEAESAKS
                     VIDSNPNLTDAAKEAAKSEIDKAVEEAIVLINGVRTYQELEKIKLPMAALIKPAAKVT
                     PVVDPNNLTEKEIARIKAFLKENNNLP"
     gene            complement(17125..19656)
                     /locus_tag="AC1PIV_000721"
     CDS             complement(17125..19656)
                     /locus_tag="AC1PIV_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015445096.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HIP6611760.1"
                     /translation="MSYKDMFRKEQRFSFRKFSFGLASAVIANVILGGAIANSPVVHA
                     NTVTEAETAVAPANQDLGNETKTEEEPKEPIEAVRTDMENRAAEILPEALNASVTNQA
                     PVIPTIGDLPKDASGQNVHGKATDNKIYRVVYVFGNVAGTTETEDGKQNVAPTFNRND
                     ATKTFPITDPDSDIQTISYEVPADIASYTLDDPNSIVTNGTSPGPVSYLDGPNGSATL
                     TQDGYLTGSFPWGAGDLAGRRIKVTDATGNTTKSNPFYMVAYTVKPVDDKPLAVSNSS
                     ELTEQAIFDKLVVDKSAKTTSNSALVIDSSNYKHSIAGYRTVNSDGTKTETVEETNLS
                     DFPTEGKYEVRVKTTNVYGQTIYNWIPVNAYKLDTAKDAEIRKYTDNQAPIHAIMQIG
                     QAGEKAAVILKDIPSDFSIENFNLKDGVADELAKRNLEFVRNDAVATTDTDGDGAKEG
                     IVGYIQPKTGGANSGVATYTGSNNLTYGFTYKAVETKDKANATEAKTLELDYTILFID
                     TKAPVMTPKSEYIRFVGEEYTVSVPGTDNAFLNTGKLNGTLSILKDGESGSLVSSDLG
                     TNTKITSELDPTGATANQGDDGQSSTKFNVKITGTGPATEGTGTYKLRVGEDNYPFGP
                     EGKLVDGNKPENVGLTSVKVTFVKHATVSTPVSVENPANLTPEEKAAVIAQIKKDNAD
                     NERLKGLPDSAFTVNSDGTVSVDYSAGGVNVDGATDIIKNATTNLADTRNEAKAEIDT
                     KLAEHKKAIEAKRDEAFSKIDDDISLRAEQRQAAKDAVAAAAGDALKELDNKATEAKE
                     KIDKATTASEINDAKTNGEINLDSAEAVGEKAINQSKRNRQRTKA"
     gene            complement(20119..21141)
                     /locus_tag="AC1PIV_000722"
     CDS             complement(20119..21141)
                     /locus_tag="AC1PIV_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family protein"
                     /protein_id="HIP6611761.1"
                     /translation="MVKENAKGVGLCFLLALVGQWLGHLFPLVGGPVFALLIGMGLYP
                     YFSSKNAFQSGLTFTSKKILQYAVICLGFGLNLSAVLAVGRQSLPIILSTISFALILA
                     FLMWKILPISSHLATLIGVGTSICGGSAIAATAPIIQADDEDVAQAISVIFLFNVLAA
                     LVFPSLATWLGFSTDSGQAFGMFAGTAVNDTSSVTAAASTWDSLYGLGSQTLDTAVTV
                     KLTRTLAIIPITTVLAIWQTRGKGLKADKKSLLAGFPTFILYFILASLITTIAGGFGI
                     GADWFAPLKSLSKFFICMAMVAIGLRTNVFALVKNGRAALMVGLVCWLGVTVLTLVWQ
                     AILGIW"
     gene            complement(21151..21474)
                     /locus_tag="AC1PIV_000723"
     CDS             complement(21151..21474)
                     /locus_tag="AC1PIV_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012774916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HIP6611762.1"
                     /translation="MIKTNILLIILMAALVTWVPRVLPFVLTQNKSLPPKLVKFLSFL
                     PITIIFALTLSSIMDEKVGSLPSFLPVESLAILPTFFVVLKTKNILLAVLVGVVTTAL
                     LRLIF"
     gene            complement(21461..22162)
                     /locus_tag="AC1PIV_000724"
     CDS             complement(21461..22162)
                     /locus_tag="AC1PIV_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HIP6611763.1"
                     /translation="MKKYAFREGMRDAIPTVLGYASIGLACGVVSVNSGISTVEMGLM
                     SLLIYAGSAQFVMCAMIFAGAPLLSIAVTVFFVNLRNFLMCLHATTIFQGNRLGSNIL
                     IGSFVTDESYAVLLRKQIEHHTITPEWMYGNNFASYASWVTFTTLGNLIGGLIPNPEQ
                     FGLDFALVAMFVGIFAGQLEAMVRTIPLKKIGLILLAVGLAYIGLSMMVSSYVAVLLA
                     TLLGCFVGVMIDDKN"
     gene            complement(22437..24638)
                     /locus_tag="AC1PIV_000725"
     CDS             complement(22437..24638)
                     /locus_tag="AC1PIV_000725"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004557 - alpha-galactosidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA];
                     GO_process: GO:0000272 - polysaccharide catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HIP6611764.1"
                     /translation="MGIIFHEKTKEFHLYNEFISYVLTVLPNGHIGSLYYGKRVTETA
                     SYQYVREDEYRALTSFVEDDDRFFSLQYANPEFACYGTTDYFSPTFELVQKDGSSLSH
                     FVYQGHAIYAGRSALKGLPHLYLDEEGQADSLDIYLLDEDSQTRLVLSYTIFRDYPAV
                     TRSARFEQLGEKSVCLNRALSMTLCLPDMDYDWLHLDGAWGRERHLQLSPLHQGCQSI
                     YSLKGASSAEHNPFMALKRPTADEQQGEVLGFSLVYSGNFLAQVDVSSFQKTRVSMGI
                     HPERFSWTLDKGEEFQTPEVVMVYSEHGLNGMSQTYHRLFQKHLVRGYWRDRERPVLL
                     NNWEAMSFDFDEETILSLAKEAAGLGVELFVMDDGWFGKRNHDRAGLGDWTVNREKLP
                     SGLTGIIDQVHAMGMKFGLWIEPEMVNRDSELYRAHPDWIFHHPQHSQSHGRHQYTLD
                     LSREDVYQNIHDQLHRLLAEHDIDYIKWDMNRYMTEVFTCTREADRQGETFHRYILNL
                     YRLYDSLIAAFPTVLFESCSSGGARFDPGMLYYAPQTWVSDDTDAMERLKIQYGTSMV
                     YPLNSMGCHVSASPNQQLGRATPLNTRANVAFFGSFGYELDLFECSQEELEEMKEQIA
                     FYKTHRKIFQQGIFTRLKSPFDGEITAWQVQSSDGQQVIVGYYRRLTTANLSYQRLYL
                     QGLEEEAVYHLDGEVYTGSQLMHTGLSIRHGDHVGDNKDFTSCLMVLQKQQ"
     gene            complement(24648..25478)
                     /locus_tag="AC1PIV_000726"
     CDS             complement(24648..25478)
                     /locus_tag="AC1PIV_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HIP6611765.1"
                     /translation="MKQSAFKSTIWMHAFLILVAMGMLIPFVWMVLTSFKTVTESTQM
                     NPFHFLPSNWMVSNYTEAIRTNNFPILYLNTILMMLWRIFSSVMFSAMAAYAFARLEF
                     PGRNFLFGLVLFQMMVPPQLFVIPQYLMIDQLGMRNTIFALVFPGIVSAFGTFLLRQF
                     FMGLPKELEESAKLDGCNIGQTFFKVMLPLAKSGLIALAIFTALFAFKDLLWPLIINS
                     EADKATLSSALSKIQGAYAVNYPQLMAASVLAIWPMLVLYVIFQKQFIQGIATSGGKL
                     "
     gene            complement(25489..26382)
                     /locus_tag="AC1PIV_000727"
     CDS             complement(25489..26382)
                     /locus_tag="AC1PIV_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HIP6611766.1"
                     /translation="MFRKKGSLNEAIWGWGMVAPTIIGLIVLNIIPIFQTMKMSFHKS
                     GDFGKGDIFVGLANYQRMLGDAQVWQATWNTLKYTILVVPATVALAMLLAVLLNSKIK
                     GKHIYRTIFFLPMVAAPAAVTMVWKWLYNTDFGLINYILRRLGLGAVNWIEDPKIALY
                     SIALIGIWSTVGYSMILILAGLQEIPTDFYEAARIDGASPAKQFFSITLPLVSPTLFF
                     VVVTSVIQSMQVFDVIYMMEDVRSPAYDKTVSLVYLFYNNSFKYSDKGYGSTIVMLLL
                     LIILVITFVQMKVQKKWVHYR"
     gene            complement(26451..27725)
                     /locus_tag="AC1PIV_000728"
     CDS             complement(26451..27725)
                     /locus_tag="AC1PIV_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HIP6611767.1"
                     /translation="MKKIGRYVTLLAAAGLLAACSTSTESSKTTGGSSSGKTEISYAI
                     WDSGQEPGLRKIADEFEKKNPDIKINIQVSDWDSYWTMLEAGATGGSLPDTFWMHSNE
                     IYRYGSNEMLLPLDEYLAKSEDAKLANFPDGLNEIYNINGKQYAIPKDFDTIGLWYNK
                     KLFDEAGIPYPDDTWDWNKLKEVAKKLTKPDGSQYGFGAGLSNQEGYYNFIYQNGGKV
                     ITDDLKSGYADPKTIEALDYYFSFVKEKISPAITVDKERAEAFQNGQVAMSVFGSWNL
                     SGFTANDYIRENADVAVLPKGPDGTRATIFNGLGHAIAATTKHPDAAWKWVEYLSSKE
                     AQEMQATLGVAISAYKGAADTWVDSNKNFTIKNYVDMVDYAQIRPYSQTTIKWEDKAY
                     ELLKPAYLGEKATEEAAKETADMMNAELATEK"
BASE COUNT         8132 a         6536 c         5200 g         7959 t
ORIGIN      
        1 attcaggtgg tcggatgtgt tttttatgtg ttaaaactct accgaatagc tctgtttctt
       61 catcgttgaa tgcatctgcc tatttttcta aaggatggat gataacacct tgcaccacac
      121 ggttgacggt gcctgttgga gatggtgtat ctggcaagtt gttgcactta atggctgcca
      181 taatagatac cgtttgggca aagaggatgt aagggaaggt taggaagaca tctggcagat
      241 ctgctccgcc ttctgccaag acaaagttgg ctgcttctgt accgactaac ttatcagccg
      301 acaatgccac tatccgctct gctatgccat caccatgaac ttcattaagc aagtccacat
      361 catactgacg agtgtaggca tcgtttgagg caaagaggaa aatcaaggtc ttttcattga
      421 tgaaggattt tggtccatga cggaaaccga gtggtgactc gtacatggtc gcaatcttac
      481 ctgctgtcaa ttccagaatt ttcaactgag cttcgtgggc aagaccatag aaaccacctg
      541 aaccgaggta aatcactcgc tcaaaatcaa ggttaatcaa gtcttgcacg tagtcttcac
      601 ggtccaaaac atcttgacct agacgggcaa tgatctcaac ccaagcagct ttttcttctt
      661 gactggctga cgagaagacg aggagggctg tcagagccat acagctgtaa gaacctgtca
      721 tggcaaagcc cttatcgttt gatccagccg gttgcaagag caggagattt tcagcatctc
      781 cttcagccgc tagtgccaac ttaccttcgg gtgcacaggt aatggtcact tgatacaatt
      841 tatctaccaa ttgcttagcg acttcaactg ctgccacact ttctggtgaa ttccctgaac
      901 gggcaaagga taccaaaacc gttggcacat ctgcctgtaa atagtcatgt gggcgactaa
      961 ccagctccac tgtaccaatg gcagaaaaac gaatgtgttt caagtcattg acttggttga
     1021 ggtagttggc aatactttgc ccaacaaagt cagaagtccc tgcacctgta aaaacaacgt
     1081 gaacaaagtc atgtttttcc ttgattgatt ttagaaaact ctcgattttt tccaattggt
     1141 caaaatagag ttgatacgct tccttccata agcctggctg ttggtaaatt tcggtcgccg
     1201 taataatagc tcccaacttt tcaagttctt cttttgctaa acggaacata gctcctcctc
     1261 cgtgatttct ggttataacc agtttttctt atattatagc gaatttatcc ctcaaagtca
     1321 atttaaaata gattaatatg tcaaatttat atccgatatt gctgactata acttatttta
     1381 agaaggtagc attatctaca taaaacatgt tataatattt actacccctc tgcctttgaa
     1441 aaagtttaac ataaggcaag gaaaatttac aaacagggtc taaccccttg atacgaaagg
     1501 aatcttaaaa atcttatgat gaacatgcaa aacatgatgc gccaagctca aaaacttcaa
     1561 aaacaaatgg agaagagtca agctgagttg gctgctactc aatttactgg tagctctgta
     1621 caagacttgg ttactgctac ttttactgga gataagaaat tggtttctat cgacttcaag
     1681 gctgatgttg tggatgcaga cgaccttgaa accttgcaag aaatgacaat ccaagccgtc
     1741 aacgctgcac ttacaaaagt tgacgaggca actcagaaaa aactaggtgc ctttgcaggt
     1801 aaattacctt tttaagacag aaaagacgcg attgggccag gccctcgcgt ctctttgttt
     1861 attcaaaatt ataaatcaaa gactgaaatt gctggaaaaa gaggtctgga tagcgtcgat
     1921 tctctttcat ttcctccatc agactttgga ggtcggtcat gttgtcagtg atgataccgt
     1981 ccacttgtag cagcaacatc ttggtcatac tctcttcttc attcggtgtc caagcataaa
     2041 ccgacttccc tcgaatccaa gacttggtca taaaattttg atccagcgag gtatactcca
     2101 tagtatagcc gtcagcaacc gtcgtcggat aaattgaatt gaacggaaga ataaagaagg
     2161 atactaattt ctcgctatac tgctttattt cgataatagt acggtaatct aatgattgca
     2221 tctggtgtcc tttggcaatc aaacgttgac cgtatttttt taagaaattc tgggtgagtt
     2281 ttggcgaatc tgccttggtc actttaattt ctaccaataa tttctgtccc agctcatccg
     2341 ctttttcaag atattcatca aaagaaggaa ctggagctgc catgccgttt tctgatgcag
     2401 tcatccctgt caactctgca agagtatagt catgtgtacc tccgggattg cccgtcaaag
     2461 ccaataaatc cgtatcatgc atgacaataa actgaccatc cttcgtctcc tgaacatcca
     2521 tctcaatata atctggcttg agctgagagg ttttctctag ggcctcgata gagttctgga
     2581 cagcattgcc gtcatcgaca cctcggtgag aaatggtaac cggcagagtg tcaaagggaa
     2641 agtagagggc aagcgctcct tgggtaccga acaccagacc agatacgagc aaaatggcta
     2701 gtcgaaggtg atgacggagg cgtttacggc ggtagattgg tagttgtttt cctgttagga
     2761 ggctgacaaa tcccatcatg aagagtgcaa ctactccgta gtaggctaat tttagaagtg
     2821 cgtaacagac aactgccagc cagtaagaag cacttggtac aaaatgctct gctaacagtt
     2881 gcacaagata gaatagtcct cctactcctg taaataggag aactggaaaa gtaaccaacc
     2941 aaattagacg gaacaatgaa ccgatctgct ttctgcctct ggtcttctcc caagaataag
     3001 cgatagactc cttcacaccc ctgtgttcaa aataaatgtt tggcagagcg tacatgaagc
     3061 gtgccgcaag ccagaagaac aagaggagga aaatcaaaat caatattcct agccagactg
     3121 tgttggatag gtaatctacg ataaattggg gcactacgat tttattaaaa taatagatat
     3181 ttaatactcg gcgtaaaaat ggaagaagaa taactgagta aaagagcaga aatagaacct
     3241 ttggtaggct actgtgacgg ataatcgcca ccatactatc tcgtacatcc cgtaaatagt
     3301 cggtgaggtg cttgactttt tcatccaaca gttgccaaac ccctgtgaac aatagagcta
     3361 attctagata ggcaatggca atgttgacaa aaaagaggag aataaacaag cctgtcacga
     3421 gcagattttc agcaaacacc gacaacaaat tcgtcggtga aaggtaggca tgccctgtca
     3481 tagctaagag tccctcagaa atccatgaat tgagcggtat ccaaacaaat tccataaagg
     3541 taaacagggt aaagaagagc aagagaatct tgtctaagtt gtaatatatt ttttgaaatt
     3601 cacgttgtat ctttttcatg attctagtgt cccatattct agcaagaatt gcaagccttc
     3661 atcaaggatg gaagattgtg aaagcaatga atgaagtata gaaaaaatca agttcctaag
     3721 tggagcttga tttcttacat ttgatttgct ttcctatttc caagccaaag taaatcgaaa
     3781 ggctacataa aatacgaatc actatctcac tattgttgta acattaattg tgcttgttta
     3841 acaatatatt ctgctgtcaa accatataca tccattaagt aagcttgttg cccaacttga
     3901 ccaaaagatt cctcaatacc aattcgatgt actggggtcg ttaaatctgt agccattaat
     3961 tcacaaatgc tactacctag gccaccaatt cgattatgat tttctacagt taatactggc
     4021 cttcctgata atagagctga tatgtcttca tgaattggtt tgatacgaaa aagatcaatg
     4081 acttgaacag atactccttg agcctctaac tgatccgccg cctttaatgc ctgctctacc
     4141 ataataccac tcgcaagcaa ggtcatatcc tccccttgcc taaggacaca gtagcctttg
     4201 ctaaaatctt ctccaccttg ataaataggc gttggcgctt tccgaatggt acgaatgtac
     4261 ttcaacccgt ctaccttgat ggtttcttta agaacagctt gaaacaggac atcgtcactg
     4321 acctcataaa cacgcgcttt tggaatgagc cgcattaagc ccagctcctc aaacggcatg
     4381 tgagtcccac cattcatctc cgctgatacc cccgcatccg accctacaat cgtggcattg
     4441 agctgggcat aagctagaga gataaacacc tgatcataga ctctacgact agcaaatggt
     4501 ccgaaggtat gaatgtatgg cttgtatcct agaagagata atccagctgc tacccctacc
     4561 atttcctgct ccatgatacc tacattgaca tagcgtcccc ccagaacaga ggacaatttg
     4621 ttggtagcca ttgaactgga taaatctgct tcaatagctg ctatggttgt gtcttcctgc
     4681 cctacctgag ctagaaaatc actataaacc agtcgcatct cctttgtctg tctcattccg
     4741 tcacctccaa ctctctcgct aaaacaagtg ttacttgctc taaatcttcc cgtaattgac
     4801 ccgacaaacg caaatggtga ttgctttcta attcttctaa gaaggtaact ccctgcccct
     4861 tagtagtatc aagaacgata cattttggtt gaggagactt acttgacttc attgttagaa
     4921 tagcatttat aatagcatct atatcggcac cattcacacg cactgattcc caaccaaaag
     4981 cctgaaattt ttcaacaaaa tcaaaggttt ggcaaatatc atgggtacga ccgtctagtt
     5041 gttttttatt gtcatccaca aacagaatca ttttcgatag ttcgtggtgg gctgcaaact
     5101 gagctgcttc ccagcattga ccttcattca attccccgtc ccctaccaga gtataggtat
     5161 agtacggtga ctgttctatc ttcttaccat aagcaacacc tgtcgcgaca ctcatccctt
     5221 gccccaacga acccgttgtc atatccaccc ctggcgttaa gtttcggtca gggtgtgaag
     5281 gcaaatgtgt tccattttga tttagcgaca agagaaaatc tctatcaaag aagcctttca
     5341 aatacaacgt actataaagt gctggacctg catgtccctt agacagaata aagtgatccc
     5401 gctccttaga agagaaattc tggacacgaa tgtccagaat ttctccatat agagcagcca
     5461 acacttctac gattgataag ctaccaccat aatgaccgaa tcctaattga ttcaaagtcg
     5521 ccaaggtatg gtagcgaatt tctttggcaa atcgtttcaa atcagctgta ccactagtca
     5581 tattatcctt ctttctgttc ttttttcacc aatgacaatc caagcatcaa agccaagaca
     5641 gcaaagatac caaccgaaac tgtgaggata ccgccattct tagctagcac tcccaggaaa
     5701 ataccagaaa gaccaaagtc tgcatctgag aaagttgaac cagcaaaacc aaggtctccc
     5761 aaaacaggaa gtaagaatac aggtaagaaa ctaatgagaa ccccttgcat aaaagcacca
     5821 caaactgcgc cacgaacacc acctgacgca tttcccatga cccctgcagt tgctccacag
     5881 aagaagtgtg gtacgacacc tggaaggata acgacaccgc cagtcaaggc aagaataatc
     5941 atgctgacaa taccacctgc aaaactagag ataaagccaa tcaacacggc gtttggtgca
     6001 taaggataaa caactggaca gtctagggct ggtttggaat tcggaaccaa cttctctgaa
     6061 attcctttga aggctggaac aatttccgct aaaattaagc gtacaccaga taagataaca
     6121 aaaacacctg ctgcaaaagt tccacctagg gtcaaggcgt aaatcatgct gttagtacca
     6181 ccactaaggt tttccttaat ataatcaccg cctgcaaaca aagccacaat catgtaaatc
     6241 aaggacatag aaatggcaat gctgacagtt gaatcacgca agaatgccaa acctttaggg
     6301 aaattaatat cctcagtaga cttagactta tcaccgacca aaccgcctac tacaccactc
     6361 aaccagtaac caagtgcact gaagtgacct agggcgacat gatcatttcc tgtcaattga
     6421 atcatgtatt tttgaacgaa ggctggggag agtgtcataa tcagacctaa agccaaccca
     6481 cccatcacaa ttaggccgac agaagtgaat cctgcaacac tcatgataac tgcaatcata
     6541 caggccatat atagtgtgtg gtgtcctgtc aagaaaatat atttaaagcg tgtaaagcgg
     6601 gcaatagcaa tattgaagac cattccaagc aacataatca aggatgtagc agttccatac
     6661 ttatccaaag ccatcgctac aatagcttca ttatttggaa caaccccttt caagttgaaa
     6721 gcttgttcaa acatttgacc aaatggctca agcgagccaa caataatatt cgctccgcca
     6781 ccaacaacaa taaaaccaac aaaagttttc aagcccccct taactaaatc tgctgcaggc
     6841 tttttctgta aggctaaacc tagaatagca atgagagcaa ccagaattgc cggagtttta
     6901 gcaatatcaa tgagaaaatc caatatcatt ttctgtctcc tttataattt tatctttgcg
     6961 ggtcatcccc tgtgtatacg atttaaacca aacctttttc ttggcagata gccgtgacaa
     7021 gttccctcaa ctcattcata tcaataatac tattcaatat tcgaacatct cctaaatgag
     7081 ttgcagaatc agccaggtca cgtccgacaa tccacacatc tgcttcactc ggattggcac
     7141 cacctagatc ataatgctcc acatgaacat ctgatacacc taaatctcgc aaaatggatt
     7201 caatattcat ttgaaccata aagctagagc ctaaacctga accacaggct gttccaattc
     7261 gtaacatatt actgttcctc ctttaataaa tgttgtacgt cggcgaattc tttggtgccg
     7321 acaagttgtt gaatattttc ttcttctcgc aaaatttttg tcaaatgcga gagtgctctg
     7381 agatgggttt gattatccac ggctgcaata caaatgaaca gccgaatttc atgactaggg
     7441 tcatccaata gataaactgg cttatccaat accaacattg acatccctac ctcattaacc
     7501 ccatcttctg gtcgtgcatg tggaatcgca attcctttac ctaggtcaat aaaaggacca
     7561 aactcttcta ccttcgctat catagcatca atatatcgag tttctatagc tcctttatct
     7621 accagaggtc gtgcagccag ggcaactgct ttttgccagt ctaaaacttc ctcagaccat
     7681 tgaaaggtct cttttgtaat caattcttct aacataggac tccttcccct ttgctcatgg
     7741 gagcgttgat tgagaaactg caccaattca tattttaaag cctgctcctg atgaatggtt
     7801 gcatgtttcc caacaagtga taataactgc tcaatctcaa tcggaaaata agccgcattt
     7861 gggaaatgct gattaaccaa atgaaataat tcttttttat gattagaggt catcagctgg
     7921 gataccaaga aaaatggtag ctctatattc agcttgatag ttccaaatac catgtcatag
     7981 tctgtcatgt ctagcatctt ccaatcctgt aaggaatggg tatcggcaaa atagatatta
     8041 ggaaatagtt gccgtagatt ttcttttaca atcagcgaag agctcactcc atttgggcaa
     8101 acaaccaagg cccgataacg atatgaacgt tgttgacctg cttcgatgta gccaccaaag
     8161 tggatgacaa aataagatac ctcactatct ggtatagtaa aacctagatg ctcttccaaa
     8221 ggtcgcaaag ctttttttac aagatagaac aagtcggcat gctcttcttt gatggtttca
     8281 gtatatgaat tgacatttac caaacgagat gttaaacggt agtaagcagg aattaggtga
     8341 cgttgcaaac cttcaatcat ttccgagcga tgttcaaaag taattaagga caaacgttcc
     8401 atctcttcca ctatttctac agtcaagtgg taaaatagat catccttttc tccgctctca
     8461 ccttctaagc atccttgcag taaatgtgac agatactctt gtgtcgcagc atttaattct
     8521 aatgtgctag tactttttaa acgtaataat ttccaaaggc gttgcagaaa atcttttaca
     8581 aaccctccct ttccttcaaa attccagtta atacggttgc caacacgcgc ctgacggata
     8641 aataaaaata tcaaaaaata caaatattca tccaatctct cttctaaagc tgagacttta
     8701 taataattgc aagcttgttg actcactatt ttcaattctt caataggatt ttcctcaccc
     8761 caagatttaa gaatataatc caaagcccac acaccaatcg aagactgcaa acaattactg
     8821 agtgcataaa gcgccaagcg atgtttatct tcttctcgac caattagatg atagcctttc
     8881 gccctcgtat attccaatcg tacttgaaag tccaagcaaa gttcctttac attcttaata
     8941 tccgtcaatg ttgtgttacg gctcacactc aataattctt ggtagtgaac gtttgataca
     9001 aattcttttc ggataaaggt ataaagatag ataagaagct gtctttcttc ttgcgaaaga
     9061 tagatctggc gattgcgaaa gagcgaaaat acactttctt tttgattgta aagctccgta
     9121 gaaataacaa actcgctatc tttgtattgt atctgcggga aggaatgttc ttgcaacaat
     9181 tgattgacta gttccaaatt agaatgtagc tgctcctttt caattcctgt ttgaatacta
     9241 agttcgtaca aactttcttt tcgagtcgca aacaattcca tcagaatcgc catggtacga
     9301 ttatcaacca tattttcctc cttgtcttaa ttgtatccct tttcatttct gatttctaga
     9361 gtctttgagc ccaattaata taatgaaaaa taaaaattca attgtgctca ctacttaaac
     9421 taaaaaagat tggttcccac caatcttttt atatcacata tcattttcca gtttttagct
     9481 cgggctgaaa cagtctatcc ccaggctgtt tcactccccc ggacctttat tcgctctctt
     9541 gttttcaagc tcatgataaa aaggtccccc ggaccttttt atttcccaaa taaacgtgca
     9601 aagaagcctt tagcttgcac ttcttctgcc tgtgctttaa cttcgtccaa ttccaacttg
     9661 agaacttcct tatcggccat agcttttagt gtcaattgct gttgctgatc caactgttta
     9721 tccttctcag caatctgcac atctttaacc ttgagttgtt catctttttc ggcaagttgc
     9781 ttatctttag cttttaattg actatataag cgaatgattt cagcattttt ctcgtcaact
     9841 aaaatttcca tcaattcacg atgcttgact tcatcactaa tcggctcatc ttcaaaaatg
     9901 gttgttttgt agatttcctc caacttaatc aagccagcac gatttacaac ggtcacaccc
     9961 ttgtcatttt tatctacaaa ttcttcagga agtgatttga cacgattatt catagcctgc
    10021 cggctcactc ctaaaatttc agctaactca ctgactgttt tttcgattcc cataatatcc
    10081 tcggtactta catttctcat agtttgtatc attaaaatat taccacagaa ccctatccct
    10141 gtcaaatcta ggggaatttc cttaccaagc attagtgaat aatcacaaac ctcaaaagca
    10201 tcttatctca atgcaatgtt atgcagaaac gaaatataca ttctatctaa taaaaccatt
    10261 tttagcactc acttgcttga accaatatcc agattttttg acagtacgct tctgagtttg
    10321 aaggtcaagc gagaccaaac cgtatcggtt cttataggta tttaaccaag accagcagtc
    10381 aataaaggtc cagaccatat agcccttaca gttcgcccct tcatcaatac ctcgatggag
    10441 ctgaatcaaa tggtcttcca tgaagtgaat ccgatagtca tcctgaatca tgccattttc
    10501 ttcaaaaaca ccctcccctt cgactcccat gccgttctca gttaccaacc attcgatatt
    10561 tccatagttt tcctggatat ttttagcaat atcgtacagc ccttcttcgt aaatttccca
    10621 gcctctatgg ggattgattt tcttgtcagg cttatcataa ggctggaaat attgggatag
    10681 gaaagtaggc tctccgttcc atccatcttc tgaaggagcc tgcacgcgca ggggctggta
    10741 ataattcacc cccaggaagt caaccctatt ttctttgata atggtcaatt cctcctctgt
    10801 ggtttctgga cgtaaaccgt gtttttcaag aatgtcaacc agctccctcg ggtattgtcc
    10861 caaaacggat ggatccaaaa agcttctcgt ttgaaatagc tcagcaatcc gtgctgcctg
    10921 taaatcttct ggactctgac ttcttggata ggcaggagta agattgagaa caatggaaat
    10981 tttgtggtct gggtgtagtt ggtgacaggc ccgaactgcc aaagaactgg ctaattgcgt
    11041 atgatacgct acgaccacag ctgcctttgc atccaccttg caaggataat gatagcttcc
    11101 tagatagcca cattctactg gaacaatggg ttcattaaag gtaatccaat gatccaccaa
    11161 atccccaaag aggctgaaac actggcgagc ataagcctca taggcccaga caatctcctt
    11221 attttcccag cccccttttt cctgtaagac ataaggcaaa tcgaaatgat aaagattgac
    11281 caaaagcttt atcccacgct ctcgaatacc tgcaaataca gccctataaa actccacagc
    11341 ttgcggattg acctcgccta tcccttccgg aatcagacgt gaccactgta tagaggtgcg
    11401 aaaaatacta tgacatgttt ccaccaacaa atccaaatct gactggaaat gttcatagaa
    11461 agtcgatgtt tgttccggtc ctatttgctg gtgaaagagc tcaggttcct gactgtacca
    11521 gtaatcccag ttattccacc cctttccatc accagctaca cttccttcac tttgaggccc
    11581 tgaagtggag gatccccaca aaaaaccttc tggaaaacga tactctcttt gctcagttac
    11641 cattcttcta cctactttct ttcatgctac agacggagtt gttagaacct ggtttcacaa
    11701 tgcagtttcc acaaaattac tttgcttgta catacaggct cctgataaaa actaatttcc
    11761 cttagtttaa gtatactccc ctaacccgtc aatggtcttc cgcaatctca aggaaaaact
    11821 ccacaaatca tagcaaagac tcaaactact ttcttgatga aaatatgata caataaaggc
    11881 atgaatacag tagataccat tattatcgga gcggggcctg ctggcatgat ggccgccatt
    11941 tcttctagtt tttatggcaa gaagaccctg cttctcgaaa aaaacaagcg tttgggcaag
    12001 aaactatctg gcacaggcgg cggacgttgc aatgtgacca acaacggcac actggaagac
    12061 ttgctggcag gcattcctgg caatggccgc tttctgtaca gcgtcttttc tcagtttgac
    12121 aaccatgaca tcatgaattt ctttcaggaa aacggggtca agctcaaggt ggaggaccac
    12181 ggccgtgtct ttccaaccac cgaccgctcc cagaccatta tcaagtgcct ggagatgaaa
    12241 atgttggaaa atggcgtgga catccgtaca ggaactgagg tggtgtccgt ccgcaagatg
    12301 gatgacctct tccatgtcaa gaccagcgag gaagtcttta cagctcccca gctgattgtc
    12361 accaccggtg gcaagaccta tccttccacc ggatcgactg gttttggaca cgacattgcc
    12421 cgccacttca agctggaagt cacggagatt gaagccgctg aaagccccgt cctgaccgac
    12481 ttcccccaca agaagctcca aggaatttcc ctggacgacg tcaccctgac ctacggcaag
    12541 cacgtcatca cccacgacct gctctttacc cactttggcc tgtcgggacc cgctgctctt
    12601 cgcttgtcca gttttgtcaa aggcggcgaa accgcatttc tcgatgtatt gccgacccat
    12661 tctgaccaag acctgtttga acatttagaa aagaacaggg aaaaatccgt taagaatacc
    12721 ctttctgaac tcatgccaga ccgtctagca gactttttcg ctgaaaacta cgatagcaag
    12781 gtcaagcaag tttcccaaaa agacctgact gaactggtca ccctcctcaa agtcttacct
    12841 atcaagatta caggcaagat gtccctggcc aagtcctttg tgaccaaggg aggcgttgac
    12901 ctcaaggaaa tcaatcccaa aaccttagaa agcaagaagg tgcctggtct ccactttgct
    12961 ggtgaggtct tggacatcaa cgcccacacc ggtggcttta acattaccta ctgccttgcg
    13021 actggctggg tggctggtag ttcctactct tcataaatca aactcagacg ttgttgactt
    13081 gatttgatga gtgtaaagct ccagtggagc tttacagcct gctacacgaa aataaaaggt
    13141 acagcgttct atctacatct aatggcacga actttgttcc cctatctcca acctccaaag
    13201 gttccccgaa cctttttgta gcgaactttg ttcgccttat ctccaacctc caaaggttcc
    13261 ccgaaccttt ggagctagtc tgagttcgat tttctttgag tagtacacta ctaattattt
    13321 aatgactgaa aaattcaagc aaaaactgct tgaatttttt tgttttttat tgtatgataa
    13381 aaccataaca atataacaaa ggagattggc tatgcaactg aaactgtctt ctatttctaa
    13441 aaaatttgat cacaagagta ttctggagga tgccagtttt caatttgaac aaggcaagat
    13501 ttacggcttg ctaggacgga acggggctgg taagacaacc ttgtttaact gcattgcccg
    13561 taatctgacc ttggataatg gctcgattca gtttgtgaaa ggcgaagaaa ctcttgacta
    13621 cgataatacg gacatcggct ttacccagac ctatccacaa ctacctgcct ttatgacagc
    13681 ctatgagttt gtccgcttct atatggacat tcataaggat aaactcaaat ctcctcgcag
    13741 tccagaagaa tggctaaact tggtcggtat tggagaagaa gaccagcacc gtctgctcaa
    13801 ggatttttcc catggtatgc agaacaaggt ccagctactc ctgtccctga ttgtccagcc
    13861 acctgtcctt ctcttagatg agccgctgac ttcctttgac cctgtggctg cccacgagtt
    13921 caaacagctg attcgggagg ctaaaaagga ttccgttatt atcttttcaa cccatatctt
    13981 acaactggct caagacctct gtgacgagat tgttttgctc catcaccaag aattgcaagc
    14041 agttccgagc gacaaactcc atgatcctga cttcgaacag gaagtagttg ccttgctgac
    14101 agcagattag gagaaaccta tgaaaacaat attacgttat tcttggtatc aggaaaaata
    14161 taacctccat cggtcagtca atggattctt ctactatctt cggaaactgc cgcttgtggg
    14221 aaagtgcatt ccagagagta ttttcaagtc ttacagcttt aagtctagtc tctttttggt
    14281 cctgcacatc ttatccatcc ccagtcgctt cctgatcaag ggcttctggt tgctctttca
    14341 tttctaccat gcttctttct ggatgaatat gctagtcaat ggggagctga ccttttggaa
    14401 aattctccca aacacttggc tccttggctt tatgttctgg cttttgtttg tcggactaag
    14461 ctatcgtttg gggaagagct tagaccctgt tatctctaaa gcagatcgag aatttatgca
    14521 gaatttcagc ctgtcacaat ccagctttct tcaaagccaa ctttttatcg agcctatcct
    14581 gaccactatt tactacctgc cagcctcaac cattttttgc atgataacca aggagtggtt
    14641 agtttttcct attggtttga tgacagtgct ggcaggtcat ctagctggcc atgccctcaa
    14701 tcgtctgctc tttgaacgtc gtatcttttc ccgtcgcaat tcgtggcatg cttggctatg
    14761 gatcgcgttt gtttttgttt tatatgtttt ggctattgtc ttccgtaatc agctctcctc
    14821 aggcatgcta gtccctatcc tgcttgtcca accatttctg atttggttta gctatggtta
    14881 tttgaagcaa caaaccaacc acctagacta tctttcctac tgtatggacg agtccttgca
    14941 aatggataag aaactttttg agatgaccaa gggaaatgaa tacactcgcc agggtttgca
    15001 gatgcaggca aaactcaatg cgaaaacagg aaaggacctg tcccacctgt ctggcatgac
    15061 ctacttaaat gctctgctat ttgaccgcta caaaaaagtc ctctataaga aggtgcagaa
    15121 ctgggtcttg gcagtagtcg tgattctggc agccctggag gggattcgtt actttttaga
    15181 tccgtttacc tttacggaag cctacttgct ccaattccta ccgctttcct tcatgattat
    15241 gtacgtagct tcgtcgggca aggtggtggc tcagatggtc tttgttaact gcgatatttc
    15301 catgcttcac tatcccttct atcgagaagc caagactatt atcgctggtt ttaactaccg
    15361 atttttgcag acctgcaagc tcaatctcat ctttgcgacc agcctctttt tggctatcat
    15421 ggtgctgggg cggtttgcct ttagtttgga aaccattcta ctaactgccc tgctcctcat
    15481 cagtctgacc gctctctttt ccttccacga tctctttatc tactatatcc tccagccttt
    15541 taccaatgac atggatgtgg tcaatcccct ctataaattt cttagcggtg ctctctactg
    15601 ggtggcctat ctcaacaccc gaatcaatgt aggtagccac acctatatcc tgctggtttc
    15661 cctagctatg attgcctatg ttagcatcgg ttactggatt ttattgaaaa aagctccgca
    15721 gacttttaga ttaaaagcat gaaaaacagc ctctcgcaag agaaggctgt tttttaggta
    15781 tgacgagcat gtcgtatcaa aaaaatccaa agtcgaatga ctttggattt tgggggttcg
    15841 atagataata actgatacct accaatcata gcgagggaat ttccttgcta tgaaagagta
    15901 tcatactact atcttctagg aaaattgcgg cttccaaaag agttctgagg aagagcttat
    15961 cttaagcttc ttcgtctctt cttctctttg ctgcaagaag tgctaatccg agtccaagag
    16021 ctactaatcc gagtgaagtt gctgaatttg cttcctcacc agtattcggt aattgcttag
    16081 ctttcttctc aacattatta gcatttgtag taactgattt aactttcact cctgctgcag
    16141 aattattttc gtctactgct acaacttcag cttctgctga atcagaacta tttccaacct
    16201 cgtctttaga gtatgctgta acaactgtac ctggcttaat aacagaacct ggaacgatta
    16261 cttgcccagt cacagggtcc acaatcacca ctgtattact tgctgtccat aaaccatccg
    16321 tacctttcgt aacaactaca gtttgcgact taccattgtt atctacgtat gaaacaacaa
    16381 gctcaacagc tttttcagac ggtacaatca caatattacc tttgccatca tttgcgaccg
    16441 taggagcagt tttatctgcc tgcttcacaa cttctactgg tgatagcaaa tcaatagttc
    16501 catctggata tttaattgtc actgaagcat ctttagaaac attaatctct gttccttatg
    16561 ggaggttatt gttctcttta aggaatgcct tgatacgagc aatttctttt tcagtcaagt
    16621 tatttggatc aaccactggt gttactttcg cagctggttt aattagagct gccattggaa
    16681 gtttgatttt ttccaactct tgataagttc taacaccatt gattaaaaca atcgcttcct
    16741 caacagcttt atcaatttca gatttagccg cttccttagc tgcatctgtc aagttcggat
    16801 tggagtcaat gactgactta gcggattctg cctctttagc aatcttgttc ttagcatctt
    16861 gtttcgcggc atcaagaatg tctttggcga tggcgcctac gcctttgtcc tctgccgatt
    16921 gcgcttcgac tggacttgtt gaagcatcaa ttgcatctgt cgcagcttta gcatctgcat
    16981 ctaccgcttt cttagctgat tccttctctg catctgtcaa gtttggattc gcgtcaatgg
    17041 ctgacttagc agcgtcggat tctttagcaa tcttattctt agcatcttgt ttcgctgcgt
    17101 caagaacatc ttgggcgatt gaacctacgc ctttgtcctc tgccgattgc gcttcgactg
    17161 gttaatagct ttttcgccta ctgcttctgc actgtccaga ttaatctcac cattagtctt
    17221 agcatcattg atttctgagg ccgtcgtagc tttatcaatt ttttcttttg cttctgtcgc
    17281 cttgttgtct aattctttca aagcatcccc agcagctgca gcaacggcat ccttagcagc
    17341 ctgtctctgt tctgctctca aggaaatgtc atcatcaatt ttagaaaacg cttcatcccg
    17401 ttttgcttcg atagcttttt tatgttcagc taattttgtg tcgatttctg cttttgcttc
    17461 attccgtgta tctgccaagt ttgtggtagc attcttaata atgtctgtcg caccatcaac
    17521 attgacacca ccggcactgt agtcaactga cacagtacca tctgagttaa ctgtaaatgc
    17581 tgaatctggc aagcccttca atctttcgtt gtctgcgttg tctttcttga tttgagcaat
    17641 aactgcggct ttttcttctg gcgttaagtt agctggattt tcaacagaaa ctggtgttga
    17701 caccgtagca tgttttacga aggtaacttt tacagatgtc aaacctacat tttctggttt
    17761 atttccatca acaagtttcc cctctggacc aaaaggatag ttatcttctc caacacgaag
    17821 cttataagtg ccggtacctt ctgtagcagg tccggtacct gtaatcttaa cgttaaactt
    17881 agttgaagat tgaccgtcat ctccttggtt tgcagttgct cccgtaggat ccagttctga
    17941 agtaatctta gtgtttgtac ctaagtctga tgatacaaga gaacctgact ctccatcttt
    18001 caaaattgag agagttccat ttagtttgcc ggtattaagg aaggcgttat ccgtacctgg
    18061 gacgctaacc gtatactctt caccaacaaa acggatgtac tctgatttag gtgtcatgac
    18121 tggtgcttta gtatctatga ataagatggt gtaatctaat tcgagagttt tagcctctgt
    18181 ggcattcgcc ttatcttttg tctcaacagc tttgtaagtg aagccataag taagattatt
    18241 tgatcctgta taagtggcta ccccactgtt tgcaccgcca gtttttggtt gaatatatcc
    18301 aacaattcct tctttggcgc catctccatc agtatcagtt gtcgccactg catcatttct
    18361 tacaaattcc aagttacgtt tagcaagctc atctgctaca ccatctttca aattgaagtt
    18421 ttcaatactg aaatcggatg gaatatcctt caatataact gctgcctttt ctccagcttg
    18481 accaatttgc attatagcat gaattggggc ttggttgtct gtatacttcc gaatttcagc
    18541 atccttcgct gtgtccaact tataggcatt tacaggaatc cagttgtaga tagtttgacc
    18601 gtaaacattg gttgttttta ctcgaacttc gtatttacct tcagttggga aatcagatag
    18661 atttgtttcc tctactgttt ctgtttttgt gccatcagaa tttacggtac gataacctgc
    18721 aattgaatgt ttgtagttgc tagaatcaat tacaagagcg ctatttgaag ttgttttagc
    18781 agacttatcg acaaccaact tatcaaaaat agcctgttcc gtcagctcag aagagtttga
    18841 tactgctaga ggtttatcat ctactggctt gactgtatat gcaaccatat agaacggatt
    18901 actcttagta gtattaccag tggcatccgt cactttaatc cgacgaccag ctaggtctcc
    18961 tgctccccaa gggaaacttc ctgttagata accatcttgt gtgagagtgg ctgacccatt
    19021 tggaccatct aagtaagata ctggaccagg tgaggtgcca ttagtaacaa ttgagtttgg
    19081 atcatccaag gtatagcttg caatatcagc tggaacttcg tatgaaatag tttgaatgtc
    19141 gctatctgga tctgtgattg gaaaagtttt agttgcatca tttctgttaa atgttggagc
    19201 aacattttgt ttaccatctt ctgtctccgt agtccctgct acattaccaa aaacgtatac
    19261 aacacgataa atcttattat ccgttgcctt accatgaaca ttctgaccac tcgcatcttt
    19321 aggaagatct ccaatagtcg gaataactgg tgcttggttt gttacactag cattcagcgc
    19381 ctccggcaag atttcagctg cacggttttc catgtccgtg cgaactgctt cgattggttc
    19441 cttgggttct tcttccgttt tagtctcatt tccaaggtct tggttagctg gtgctacagc
    19501 tgtctctgct tctgtcactg tgttagcatg aacaacaggg ctgtttgcga ttgctcctcc
    19561 caaaataacg tttgcaatga ctgccgaagc tagaccaaag ctaaatttac gaaaagaaaa
    19621 acgttgttct tttctgaaca tatctttata agacatgata tcctcctata ttttactggc
    19681 gaatgccatc atttctggtt cctgtaacac catgtacaaa aacacacctc ctgctttaaa
    19741 aacttagcag aaggataccc agtagattat ttattttaaa gtagacagaa tgttttcatc
    19801 cagagtatat aaaatttcta cttgaatacc gtcaccatta tactccttat gcctcaaaga
    19861 tacaagaaaa aatctgttat ttttgaggtt tttttgaaaa atttactgaa aatctatcat
    19921 atttatataa aggaagacaa atatcgtgta aacagcctac ttaaaaagac aattcaatta
    19981 cattttaaac aaaactaact agttttaagt tgttcaacgg tactaaaaac cgaacgacaa
    20041 aaagccctgc ggcactgcga tttacttctc aaaaattgtt tgaaatagga aatgatgtct
    20101 ttcccactca catttctctt accaaatccc caaaatcgct tgccagacca gtgtcaacac
    20161 cgtcactccc agccagcaaa ccagaccaac catgagagcc gctctgccat ttttcaccaa
    20221 ggcaaacaca ttggtccgca aaccaatcgc caccatagcc atacaaatga aaaatttaga
    20281 gagggacttc aacggagcaa accaatctgc ccctatacca aatccacccg ctatcgttgt
    20341 gattagacta gctaagataa aatacaagat aaaggtcgga aaacctgcca agagggactt
    20401 cttgtctgcc ttgagaccct ttcctcgggt ttgccaaatt gctaaaaccg ttgtaatcgg
    20461 gataatggct aaagttcgtg ttagcttaac cgtcactgct gtatctaagg tctgactgcc
    20521 tagaccatat aagctatccc aagtcgaagc cgctgctgtc acagaggagg tgtcattgac
    20581 cgccgttccg gcgaacatcc caaaggcctg acccgaatca gtcgaaaacc caagccaagt
    20641 tgccagacta ggaaagacca aagccgccaa gacattgaag agaaagatga ccgagattgc
    20701 ttgtgccaca tcctcatcat ctgcctgaat aatgggagca gtcgccgcaa tggcagagcc
    20761 tccacagata gaggtaccta cgccaatcaa ggttgccaga tgagatgaaa tgggcaagat
    20821 tttccacatc agaaatgcca aaatcaaagc aaaactaatg gtcgaaagaa taattggaag
    20881 agattgacgc ccaactgcca agaccgctga taagtttaat ccaaatccca aacaaatcac
    20941 agcatactgt aaaattttct tggaagtaaa ggttaagcct gactgaaatg catttttact
    21001 tgaaaaatag ggatacagac ccatcccaat tagaagggca aaaacaggcc cacctacaag
    21061 tggaaataaa tgacctaacc actgacccac caaagccaaa aggaaacaaa gtccgacacc
    21121 tttggcattt tcttttacca taaaaacctc ctaaaatatc aaacgtaata acgcggttgt
    21181 aacaacgcca accaagactg ctaaaaggat attttttgtt ttcaaaacca caaaaaatgt
    21241 cggaagaata gctaagcttt ccacagggag aaaacttggc aaggagccaa ctttctcatc
    21301 cataatactg gagagggtca atgcaaaaat gatagtgatt ggcaaaaagc tgaggaattt
    21361 caccaacttt ggagggagag atttattttg cgtcaggaca aaaggcagga cgcgtggcac
    21421 ccaggtcacc agggccgcca ttagaataat cagtaaaatg ttagttttta tcatcaatca
    21481 tcacccccac aaagcaacct agtagtgtcg ccaagagcac tgccacatag gacgacacca
    21541 tcatagacag accgatatag gccagaccga ctgccagcag aattaagcca atttttttca
    21601 gcggaatggt ccgaaccata gcctctaact gacctgcaaa aataccgaca aacatagcaa
    21661 ccaaggcaaa gtccaatcca aactgctcag gatttggaat gagaccacca atcagattgc
    21721 cgagagtcgt gaatgtaacc caagaggcat agcttgcaaa attatttccg tacatccatt
    21781 ctggagtaat ggtatgatgc tcaatctgct tacgcaaaag aactgcatag gattcatccg
    21841 tcacaaagga tcctatcaag atattcgacc ctaaacgatt tccttgaaaa atagttgtcg
    21901 catgcaagca catcagaaaa ttacgcaggt tgacaaagaa aacggttact gcaatggata
    21961 acaaaggcgc acctgcaaaa atcatggcac acatgacaaa ttgagcactc ccggcataga
    22021 ttaataggct catcagcccc atctccacag tagaaatgcc cgaattaacc gatacgactc
    22081 cgcaggctag accaatactg gcatagccca atacagtggg aatggcatcg cgcatccctt
    22141 cacgaaaagc atatttcttc attcattatc tcccttcccc tcactaattg attgaagaat
    22201 tattctctca ttttctcaca ttgcaacccg tttttcaaga attcttatat ctaatactca
    22261 atgaaaatca aaagtagcct aggaaacgaa gccgaagata gaactggagt tcatcaaggc
    22321 aagttgacaa cggataattt tgattttcga agagtataag tagaggtctt gcccttattg
    22381 atgtactttc tgcataaaat agacccagcc gatagctggg cctaggaata gggatgctac
    22441 tgttgtttct gaaggaccat caaacaagaa gtaaagtcct tattgtctcc aacatggtcc
    22501 ccatgtcgaa tcgacaaacc tgtatgcatt aattggctac cagtataaac ttctccatca
    22561 aggtgataga ccgcttcctc ttccaatccc tgcaaataca agcgttgata ggagagatta
    22621 gccgttgtca accgacgata ataacccacg atgacttgct gaccatccga ggattggacc
    22681 tgccaagccg ttatttctcc atcgaatgga cttttcagac gagtgaaaat accctgttgg
    22741 aaaatcttac ggtgagtctt gtaaaaggca atctgctctt tcatctcttc caactcttct
    22801 tggctacact caaacaaatc caattcatag ccaaaacttc caaagaatgc aacattggca
    22861 cgtgtgttta gtggagtagc acgccccaac tgctgatttg gactagctga cacatggcaa
    22921 cccatactat tcaaaggata gaccatgctc gttccatatt ggattttcaa gcgttccatg
    22981 gcgtccgtgt catcgctgac ccaggtttgc ggtgcatagt agagcatccc tggatcaaat
    23041 ctagctccac cacttgaaca agattcgaat aagactgtcg gaaaagctgc tatcaggcta
    23101 tcatataaac ggtagagatt gagaatatag cgatggaagg tctcaccttg tcgatccgcc
    23161 tcccgtgtac atgtaaagac ctctgtcata tagcgattca tgtcccactt gatataatca
    23221 atatcatgct cagccaacag ccgatggagt tggtcatgaa tattttgata aacatcctcc
    23281 ctcgacaaat ccagcgtata ttggtggcgt ccgtgcgatt gactatgctg aggatgatgg
    23341 aaaatccagt ctggatgcgc tcggtaaagc tcgctgtccc tattgaccat ttcaggttcg
    23401 atccaaagtc caaatttcat tcccatagca tgaacttggt caataatccc tgtcaagcca
    23461 cttggtaatt tctctcggtt gaccgtccaa tctcccaagc ctgctcggtc atggtttcgc
    23521 ttgccaaacc aaccatcatc catgacaaag agttcaacac caagacctgc agcctctttg
    23581 gccaaggaaa gaattgtttc ctcatcaaaa tcaaaactca tggcttccca gttattcaag
    23641 agaacaggtc gttctctatc acgccaatag ccacgtacca gatgtttttg gaagaggcgg
    23701 tgataggttt ggctcatgcc attcaaacca tgctcgctat aaaccataac aacctcaggc
    23761 gtctggaact cttctccctt atctaatgtc caagaaaaac gctcaggatg gattcccata
    23821 ctcactcttg ttttttggaa agaactcaca tccacctgcg ccaaaaagtt tccgctatag
    23881 acgagcgaga agcctagtac ctctccctgt tgctcatccg cagttgggcg tttcaaagcc
    23941 ataaagggat tgtgctccgc actactagcc cctttgagac tgtaaataga ctgacaacct
    24001 tgatgaagag gcgatagttg cagatgccgc tcacgccccc aagccccatc caaatgcaac
    24061 caatcatagt ccatatcagg cagacaaagt gtcatactca aggcacggtt caaacagaca
    24121 gatttttctc cgagttgttc aaaacgagca gagcgagtca ccgctggata atctcgaaaa
    24181 atcgtataag acaagaccag ccgggtctgc gaatcttcat ccaacaaata aatatccaaa
    24241 ctatctgcct gtccctcctc atccagatag agatgaggaa gacccttcaa agccgatcgc
    24301 ccagcataaa tcgcatgacc ttgatacaca aagtgcgata gactgctacc atccttctgc
    24361 accaactcaa aagtcggaga aaaatagtcc gttgtaccat aacaagcaaa ttcaggattg
    24421 gcatattgga gcgaaaagaa acggtcatcg tcttctacaa aggaagtcaa agcacgatac
    24481 tcatcttcac gtacatactg ataagaagct gtttctgtta cacgctttcc ataatacaaa
    24541 ctaccaatat gaccattagg caagaccgtc aacacatagc taataaactc attgtaaaga
    24601 tggaattcct ttgtcttttc atgaaagata attcccattg tagcctccta taattttcca
    24661 ccagatgtcg caatcccttg gatgaactgc ttctggaata tcacatacag taccaacatc
    24721 ggccaaatag ccaaaacact tgcagccatg agctgaggat agttaacagc gtaagctccc
    24781 tgaatcttag aaagtgcgct agatagggta gccttgtcag cctctgagtt gataatcaat
    24841 ggccacagca aatccttgaa agcaaacaaa gccgtaaaaa tcgctaaggc aatcaagcca
    24901 gacttggcca atggcaacat gaccttaaag aaggtctgcc cgatattaca accatccaat
    24961 ttcgcagact cctccaattc ttttggaagc cccatgaaaa attgacggag caagaatgtc
    25021 ccaaaggcac tgacaattcc tgggaatacc agagcaaaaa tcgtattgcg cataccaagt
    25081 tggtcaatca tcaaatactg aggaatgacg aataactgag gtggcaccat catttgaaag
    25141 aggaccagac caaacaagaa attccgccca ggaaactcca gtcgagcaaa ggcataagct
    25201 gccatagctg aaaacataac cgagctaaag atacgccata acatcatcaa aatggtgttc
    25261 agatagagta tcggaaaatt attagtccga atagcctccg tataattgct caccatccag
    25321 ttacttggta aaaagtggaa aggattcatc tgagtggatt cggttaccgt tttaaaagac
    25381 gtcaacacca tccaaacaaa tgggatcagc atgcccattg ccactaaaat caagaaggca
    25441 tgcatccaga ttgttgattt aaaagctgat tgtttcacat gaacctcctt aacggtaatg
    25501 cacccatttt ttctgtacct tcatctgaac gaaagtaatg acaagaataa tcaataacaa
    25561 caacatgaca atggtggagc catagccctt atccgaatat ttaaaggaat tattgtaaaa
    25621 cagataaacc agagatactg tcttatcata ggcaggacta cgaacatcct ccatcatata
    25681 gataacatca aagacttgca tggattgaat gacactggtt accacaacaa agaacagggt
    25741 tggtgaaacc aatggcaggg taatggagaa aaattgcttg gccggactag ctccatcaat
    25801 gcgagctgcc tcataaaaat ccgttggaat ttcttgcaaa ccagctaaaa ttaaaatcat
    25861 actatagcca accgtactcc aaattccaat caaagcgatt gagtatagag caatctttgg
    25921 atcttcaatc cagttcacag cacccagtcc caaacgacgc aagatatagt taatcaagcc
    25981 gaagtccgta ttgtagagcc atttccaaac catggtcacc gcggctggtg ctgccaccat
    26041 aggcaagaaa aaaatggttc gataaatatg cttaccttta atcttagaat taagcaaaac
    26101 tgcaagcaac atggccaagg caacggtagc cggaacaact agaatcgtat atttcaaggt
    26161 attccatgtc gcctgccaca cttgcgcatc ccctaacatg cgttggtaat ttgccaagcc
    26221 gacaaagatg tcacctttgc cgaaatctcc actcttatga aaactcatct tcatggtttg
    26281 gaaaatagga ataatattga gcacgattaa tccaataatg gtcggtgcta ccattcccca
    26341 tccccaaatt gcctcattta aacttccttt ttttcggaac atcttatccc catccttctt
    26401 cattttaata agaaggtccg gggaagaatc aacttcccaa gacctcctac ctatttttca
    26461 gttgctaatt cagcattcat catatcagct gtttctttgg cagcttcttc agttgctttt
    26521 tctccaagat aagcaggttt caatagctca taagccttat cttcccactt gatggttgtt
    26581 tgtgaatatg gacgaatctg tgcataatcc accatgtcaa cataattctt gatagtaaag
    26641 tttttgtttg aatctaccca agtatctgcc gcgcctttat aagccgagat tgccacacca
    26701 agtgttgcct gcatttcttg tgcctctttt gagctgaggt attcaaccca tttccaagca
    26761 gcatctggat gtttagtggt agcagcaatg gcatgaccca atccattaaa gatggttgca
    26821 cgagttccat ctggaccttt tggcaaaaca gctacatcag cattttcacg aatgtagtca
    26881 ttagcagtga aaccagataa attccaagaa ccgaagacgc tcatagccac ttgaccgttt
    26941 tggaatgctt cggcccgctc tttatctact gtaatagccg gtgaaatttt ttctttgaca
    27001 aagctaaagt agtaatccaa agcctcaatg gtcttaggat cagcatagcc tgatttcaaa
    27061 tcatcagtaa taaccttacc accattttga tagataaagt tgtagtagcc ctcttggtta
    27121 ctcaaaccag caccgaaacc atactgacta ccatctggct tggtcaattt cttcgctact
    27181 tctttcaact tattccaatc ccaagtatca tctggatatg gaatgcctgc ttcgtcaaat
    27241 aattttttat tgtaccaaag accgattgta tcgaaatctt ttggaatagc gtactgctta
    27301 ccatttatgt tgtagatttc attcaaacca tctgggaaat tagctagttt ggcatcttca
    27361 ctcttggcta agtattcatc caatggcaat agcatttcat tggaaccata gcgataaatc
    27421 tcatttgaat gcatccagaa ggtatcaggc aatgaaccac ctgtcgcacc agcttctaac
    27481 atggtccagt aggaatccca gtccgatact tgaatattga ttttaatatc tggattcttt
    27541 ttctcaaact catccgcaat ctttctcaaa ccaggctctt gaccagaatc ccaaatagca
    27601 taggatattt ctgtctttcc tgaactactt cctcccgtag ttttgctaga ctcagtcgaa
    27661 gtagaacacg ctgccagcag gcctgcagcc gcaagcaagg taacatagcg accaattttc
    27721 ttcatgataa tactcctttt cttttgtcga atacgtcgac gaactttgtt atttctacta
    27781 taactataac atgtaagcgc tttataatca aataggaata tttgaca
//
LOCUS       DBNFCO010000020        27816 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.020, whole genome shotgun sequence.
ACCESSION   DBNFCO010000020 DBNFCO010000000
VERSION     DBNFCO010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 27816)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27816)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27816
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.020"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(223..711)
                     /locus_tag="AC1PIV_000729"
     CDS             complement(223..711)
                     /locus_tag="AC1PIV_000729"
                     /inference="COORDINATES: protein motif:HMM:NF015734.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PASTA domain-containing protein"
                     /protein_id="HIP6611768.1"
                     /translation="MAPQVVPNVVGKSQENATQILQTAGFSIGTITQEYSSSVTAGQV
                     ISTDPVANTELAKGSIINLVISKGKELIMPDLTSGNYTYSQARSQLQALGVNAESIEK
                     QEDRSYYSTTSDIVIGQYPAAGATIDGTVTLYVSVASTRTSSDSSAGSSTSTSTSTGS
                     GQ"
     gene            complement(688..2217)
                     /gene="pknB"
                     /locus_tag="AC1PIV_000730"
                     /pseudo
     CDS             complement(688..2217)
                     /gene="pknB"
                     /locus_tag="AC1PIV_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893497.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004672 - protein kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
     gene            complement(2217..2954)
                     /locus_tag="AC1PIV_000731"
     CDS             complement(2217..2954)
                     /locus_tag="AC1PIV_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HIP6611769.1"
                     /translation="MEIALLTDVGQKRSNNQDYINRYKNRAGIDLVVLADGMGGHRAG
                     HIASEMAATDLGAAWVDTQLVTLNDVREWMVAIIDAENQKIHELGQTEEYKGMGTTLE
                     AVVVIDNQMIYAHVGDSRVGLIRDGEYTRLTNDHSLVGALVRAGQLTEEEAQRHPQKN
                     IVTQSIGQAEPIEPDIALKTLEVGDYVLINSDGLTNMIPTEDIRDIVLSDVSIESKVE
                     TLVRFANNAGGLDNITVGLLHITEEAR"
     gene            complement(2992..4305)
                     /gene="rsmB"
                     /locus_tag="AC1PIV_000732"
     CDS             complement(2992..4305)
                     /gene="rsmB"
                     /locus_tag="AC1PIV_000732"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HIP6611770.1"
                     /translation="MVINKHETARSLALSVLEQVFDQGAYSNIALNKALESSRLSAQD
                     KGLATELVYGTVSRKITLEWYLAHFIEDREKLDTWVYYLLMLSLYQLVYLDKLPTHAV
                     VNEAVNIAKRKPGTDKFVNAILRKLSQDSLPKPADIKRKNKRLSVQYSVPVWLVQTLI
                     AEYGDERAEKIFQSLHDRNKASVRVTDGQQVERLAEELGAQHSQLSPVGLVKPHGHFA
                     GTDYFKEGLITIQDETSQLVAPTLDIQGDEIILDACAAPGGKTCHMASYLTDGKVYAL
                     DLYDHKLNLIEENARRLGLADKIETKGLDASRVHEEFGPDTFDKILVDAPCSGIGLIR
                     RKPDIRYNKASMDFDSLKTIQLQILDSVCQSLKIGGIITYSTCTIIAKENQEVIQEFL
                     QNHPNFEQVTLEHPQTDIMVDGCLLITPEQYKTDGFFIGQLRRKS"
     gene            complement(4292..5230)
                     /gene="fmt"
                     /locus_tag="AC1PIV_000733"
     CDS             complement(4292..5230)
                     /gene="fmt"
                     /locus_tag="AC1PIV_000733"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HIP6611771.1"
                     /translation="MTKLIFMGTPAFSATVLRGLLADGNYNILAVVTQPDRAVGRKKV
                     IQMTPVKEVALEYNLPVYQPEKLSGSQEMDELMNLGADGIVTAAFGQFLPTKLLNSVD
                     FAVNVHASLLPKYRGGAPIHYALINGDERAGVTIMEMVKEMDAGDMISSDSIAIEESD
                     NVGTLFEKLAVVGRDLLLQTLPAYIAGDLKPVAQNPEQVTFSPNIQPEEEVLDWNKTA
                     RQLFNQIRGMYPWPVAHTYWQGERFKIQEAVEAEGEGSVGRVIARSKKELIIATGQGA
                     LSLKTVQPAGKPKMTIADFLNGAGRDIAVGDQFGDQ"
     gene            complement(5362..7752)
                     /locus_tag="AC1PIV_000734"
     CDS             complement(5362..7752)
                     /locus_tag="AC1PIV_000734"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HIP6611772.1"
                     /translation="MLAQIIVDVPLMQTDQAYSYRVPAELEEGLKVGVRVHVPFGKGN
                     RLIQGIVVDLIDEDDENSLQDLKELAEVLDYSPVLNQEQFWLADQMRKSVFSYKITLL
                     KSMLPSLLNSTYDKLIRPGIGLEMAEQISLFGDKEQIRFSDLDVTEQGKIMRLAQSGK
                     ILVDYVAKDKKQIKTEKWYRVCLEKLREADISNRAKKRQQLREFLLEQSEDQLLSNLK
                     SDYSADTLRYFQEKGYIEVWEEEVSRTQGVFDKVEKTQALDLNPEQAIAVREIVASIG
                     QESQTFLLQGVTGSGKTEVYLQVIDRVLKMGKTAIMLVPEISLTPQMTNRFISRFGQQ
                     VAILHSGLSDGEKYDEWRKIEAGNAQVVVGARSAIFAPLTNLGVIIIDEEHEATYKQD
                     SNPRYHARDVAKLRADYNRATLVLGSATPSLETRARASRGVYGRLTLNQRANPLARIP
                     EVEVVDFRDYIGQQEASNFTPVLIEKIREKLARKEQVVLMLNRRGYSSFVMCRDCGSV
                     DQCPNCDISLTLHMDTKTMNCHYCGFQKGIPQTCPNCQSRSIRYYGTGTQKAYDELQE
                     LLPEARILRMDVDTTKKKGAHEDLLERFGRGEADILLGTQMIAKGLDFPNVTLVGVLN
                     ADTALNLPDFRSSERTFQLLTQVAGRAGRADKEGEVLIQTYNPNHYAIAFAKEQDYEG
                     FYRYEMDIRKNLGYPPYYFTVGLTFSHKSEEFVVKKAYETVAFLRQHLTDAIQILGPT
                     PKPIARTHNLYHYQIILKYRHEDRLEEVLNQILDWTQERENQDLRLIIDNEPQNMM"
     gene            complement(7945..8259)
                     /gene="rpoZ"
                     /locus_tag="AC1PIV_000735"
     CDS             complement(7945..8259)
                     /gene="rpoZ"
                     /locus_tag="AC1PIV_000735"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed RNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HIP6611773.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAKPTQEFTSV
                     KSTLRALEEIESGNVVIHPDPEAKREAVRRRAEEAKRLAEEEERKIKAQIAKEKEEGE
                     KI"
     gene            complement(8283..8909)
                     /gene="gmk"
                     /locus_tag="AC1PIV_000736"
     CDS             complement(8283..8909)
                     /gene="gmk"
                     /locus_tag="AC1PIV_000736"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012774981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - guanylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HIP6611774.1"
                     /translation="MKERGLLIVFSGPSGVGKGTVRKEIFESSDNKFEYSVSMTTRPQ
                     RPGEVDGVDYFFRSREEFEDLIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDGVFIFLTPPDLEELQDRLIGRGTDSEEVIAQRIERAKEEIALM
                     REYDYAVVNDEVPLAAERVKRIIEAEHFRVDRVIGRYDEMIREQIVER"
     gene            complement(9064..10677)
                     /locus_tag="AC1PIV_000737"
     CDS             complement(9064..10677)
                     /locus_tag="AC1PIV_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HIP6611775.1"
                     /translation="MNIITVVVTLVSALIGLVLGYFAISLKMKSAKETAELTLLNAEQ
                     EASNVRGRAEEQAEVILKTAERDRQTLKKELLLEAKEEARKYREEIAEEFKSERQELK
                     QIESRLTERATSLDRKDDNLTNKEKTLEQKEQSLTDKAKHIDEREQEVVKLEEQKALE
                     LERVAALSQEEAKEIILTDTRDKLTHEIATRIKEAEREVKERSDKMAKDLLAQAMQRI
                     SGEYVAEQTITSVHLPDDAMKGRIIGREGRNIRTFESLTGIDVIIDDTPEVVVLSGFD
                     PIRREIARMTMETLLQDGRIHPARIEELVEKHRVEMDNRIREYGEAAAYEVGAPNLHP
                     DLIKIMGRLHFRTSYGQNVLRHSIEVAKLAGVLAAELGENVNLARRAGFLHDVGKAID
                     REVDGSHVEIGTELAKKYKENPIVINAIASHHGDVEATSTIAVIVAAADALSAARPGS
                     RRESMEAYIKRLQDLEEIANSFEGIKQSYAIQAGREIRIIVHPNKVTDDQITILAHDV
                     REKIENNLDYPGNIKITVIRETRATDVAK"
     gene            10807..11289
                     /locus_tag="AC1PIV_000738"
     CDS             10807..11289
                     /locus_tag="AC1PIV_000738"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002885585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HIP6611776.1"
                     /translation="MKKEVTVESFELDHTIVKAPYIRLISEEVGPKGDIITNFDIRLI
                     QPNENAMDTAGLHTIEHLLAKLIRQRIDGLIDCSPFGCRTGFHMIMWGKQDSEKIAQV
                     IKSSLEEIAEGITWEDVPGTTIESCGNYKDHSLHSAKEWAKLILSQGISTDAFERKPI
                     "
     gene            complement(11672..13126)
                     /locus_tag="AC1PIV_000739"
     CDS             complement(11672..13126)
                     /locus_tag="AC1PIV_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division site-positioning protein MapZ
                     family protein"
                     /protein_id="HIP6611777.1"
                     /translation="MGEKNSHHLPLDEEKVLDFEVAKDLTIEEAVKKHKEIEAGVTED
                     DGLLDRYIKQHRAEIESQKFETKINHLPLVEVADEEKNQGHESAEEVEANESSLTEVS
                     EEIAPIVEELSVTPMETLEETVIASTVAMEGLSSVADDSSLELEEDETEDLDHSEGAD
                     RDQKKKFYFWSAVGLSMIGVMATALVWMNSVNKSNTATSSSSTSTSQTSSTASSSTDA
                     NVTAFEQLYNSFFTDSSLTKLKNSEFGKLAELKVLLEKLDKNSDSYTKAKEQYDHLEK
                     AIAAIQAINGQFDKEVVVNGEIDTTATVKSGESLSATTTGISAVDSLLASVVNFGRSQ
                     QEVASATVASEAAVTRNQGADETVSTGVPATTEVASTTVSGSTTDFGIAVPAGVVLQR
                     DRSRVPYNQAMIDDVNNEAWNFNPGILENIVTISQQRGYITGNQYILEKVNIINGNGY
                     YNMFKPDGTYLFSINCKTGYFVGNGAGHSDALDY"
     gene            complement(13136..14302)
                     /locus_tag="AC1PIV_000740"
     CDS             complement(13136..14302)
                     /locus_tag="AC1PIV_000740"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="THUMP domain-containing class I SAM-dependent
                     RNA methyltransferase"
                     /protein_id="HIP6611778.1"
                     /translation="MKKQFELIATAAAGLEAVVGREIRNLGYECQVENGRVRFQGDVK
                     SIIETNIWLRSADRIKIIVGQFPAKTFEELFQGVFNLDWENYLPLGCKFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHFSRPEGVPLQEMGAEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRVEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAAMLAKN
                     IAPGLKRSFAFEEWPWVEDQLVVALRKEAQASIKTDLVLDITGSDIDARMIEIAKKNA
                     FAAGVEQDIVFKQMRVQDLRTDKINGVIISNPPYGERLLDDEAIVTLYREMGETFEPL
                     KTWSKFILTSDELFETRFGQQADKKRKLYNGTLKVDLYQFFGQRVKRQVQEVQG"
     gene            complement(14356..14720)
                     /gene="rnpB"
                     /locus_tag="AC1PIV_000741"
     ncRNA           complement(14356..14720)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="AC1PIV_000741"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(14859..15194)
                     /gene="gpsB"
                     /locus_tag="AC1PIV_000742"
     CDS             complement(14859..15194)
                     /gene="gpsB"
                     /locus_tag="AC1PIV_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HIP6611779.1"
                     /translation="MASIKFTTKDIFEQDFKIGFRGYDQDEVNDFLDDIMKDYDAYEA
                     IIKELKGEIARLKAQAANSPKTTLPTEESNDVLRTERPSSATNFDILRRLNRLEKEVF
                     GKQIVQDQE"
     gene            complement(15265..15804)
                     /locus_tag="AC1PIV_000743"
     CDS             complement(15265..15804)
                     /locus_tag="AC1PIV_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HIP6611780.1"
                     /translation="MDTKSLLVTGYRHTDLGIFSEKDPRLHIIKSAIRRNFIRFLEEG
                     VSWFILTGQLGFEYWSLEVLEDLRAEGYQLSIATIFPFENHGEQWNEANQAKLARFKQ
                     VDFVKYAYPRYENPGQFRDYNQFLLDNTTGCYLFYDSENETNLKYLYHMVLKKEGYNR
                     KTLTFEELNEEAENFSNSE"
     gene            15870..16487
                     /gene="recU"
                     /locus_tag="AC1PIV_000744"
     CDS             15870..16487
                     /gene="recU"
                     /locus_tag="AC1PIV_000744"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HIP6611781.1"
                     /translation="MVNYPHKVSKKINRTSPISSQRVNFANRGMSFEAAINDSNQYYL
                     AHDIAVIHKKPTPVQIVKVDYPKRSRAKIVEAYFRQASTTDYSGVFKRHYIDFEAKET
                     RQKASMPMKNFHAHQIEHMKQVVKQGGICFVLLHFSTLKETYLLPATHLIEFYQVDMG
                     SKSMPLTFIRQYGFEIQMGRFPSIPYLEIVEKNLLGGESFENYNN"
     gene            16468..18642
                     /gene="pbp1a"
                     /locus_tag="AC1PIV_000745"
     CDS             16468..18642
                     /gene="pbp1a"
                     /locus_tag="AC1PIV_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP1A"
                     /protein_id="HIP6611782.1"
                     /translation="MKTTTIKKALLITANILLAGAIIACLAGAALVVYYIQSAPELTE
                     ESLTATVSSKIYDKNGNLIADLGAEKRSSAKTEEIPTDLVNAIVAIEDQRFFNHRGVD
                     VIRIAGSLINNLSGGRLQGGSTLDQQFIKLTYFSTSVEDQNLKRKIQEAWLATQLERR
                     NTKQEILTYYINKVYMSNGNYGMKTAALAFYGKELKDLTLPQLALLAGMPQAPNQYDP
                     YTNPEDAKARRDLVLAEMLEEKYIDNTQYEQAVLTPVTDGLQPLSNAAAYPAYMDNYL
                     KQVVEEVEAKTGYNLLTTGMDVYTNVDPAAQQQLWNIYNTDMYVSYPDDLLQVASTVV
                     DVSNGKVVAQLGGRKQETNVSFGTNQAVETNRDFGSTMKPITDYAPAFENGIYTSTAD
                     LILDGPYNYPGTPTPVNNWDKQYYGNISVKTAIQYSRNVTAVKALEATGLENALKFLN
                     SVGINYPDIHYSNAISSNTSDTSSKYGASSEKMAAAYAAFANGGTYYAPQYVNKIVFS
                     DGTVTEYAPKGTKVMSAETAYMMTDMMKAVMSYGYGLNASVSGVPMAGKTGTSNYTDS
                     ETDTILASIPEANYSYMVVPDENFVGYSSQYAMAVWTGYTNRMTPILDNSMRIATDVY
                     HNMMLFMHSDYTATDWEMPSGLVRYGSNYYLRGSRSLSNAYNTYTSSSTSSSSSTETS
                     ETTEATTTSSETSSGTATETATSSTETATTGNNPATGQTDGQ"
     gene            18701..19414
                     /gene="rsmG"
                     /locus_tag="AC1PIV_000746"
     CDS             18701..19414
                     /gene="rsmG"
                     /locus_tag="AC1PIV_000746"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA];
                     GO_process: GO:0046118 - 7-methylguanosine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HIP6611783.1"
                     /translation="MKPEVFYKTLADQGIQLTDQQKHQFHRYFQLLVEWNEKINLTAI
                     TEESEVYLKHFYDSIAPLLQGHIQNEPLRLLDIGAGAGFPSLPMKIIFPQLDVTIIDS
                     LNKRINFLHLLAEELELEGVHFYHGRAEDFAQDKNFRAQFDLVTARAVARMQILSELT
                     IPYLKLHGKLIALKASSAEDELTQAKNALNLLFAKVIENHDYTLPNGDPRTLTIVEKK
                     KETPNKFPRKAGMPNKRPL"
     gene            complement(19456..19659)
                     /locus_tag="AC1PIV_000747"
     CDS             complement(19456..19659)
                     /locus_tag="AC1PIV_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HIP6611784.1"
                     /translation="MVQGTVKWFNAEKGFGFIAQENGPDVFAHFSEIQSNGFKSLEDG
                     QKVTFEVEQGQRGLQATNITKIG"
     gene            complement(19819..20652)
                     /locus_tag="AC1PIV_000748"
     CDS             complement(19819..20652)
                     /locus_tag="AC1PIV_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     component T family protein"
                     /protein_id="HIP6611785.1"
                     /translation="MSQQKLIGYHPGTGLIHSLSAVSKLLFFLIVSILAMITYDTRLI
                     LFIAVFSLALFKMSGIRYKEISLVLILTIIFAAMNALMVHLFAPRYGVELYGADTPLL
                     SGLGVYSLTSQQAFYLVNLLLKYFCTVPLAIIFLMTTHPSQFASSLNQIGVSYKVAYA
                     VSLTMRYIPDIQEEFYTIRMSQEARGLELSKKGKLMDRIKGNLSLVIPLIFSSLERID
                     TISTAMELRRFGKNKKRTWYTQQPLQRIDYAVLLFILALVVVTIYLFFVNQGRFYNPW
                     R"
     gene            complement(20649..22322)
                     /locus_tag="AC1PIV_000749"
     CDS             complement(20649..22322)
                     /locus_tag="AC1PIV_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIP6611786.1"
                     /translation="MKKIIEFKDFTFKYQAQQEPTLKDIQLTIYQGEKVLIIGPSGSG
                     KSTIGQCLNGIIPNIYKGEHSGSLLLDGQEAFNLSVYDKSLLVSTVLQDTDGQFIGLS
                     VAEDLAFALENDMESQVVMKQKVGDWAERLSLTDLLAHRPQDLSGGQKQRVSLGGVLI
                     DESPILLFDEPLANLDPKSGQDTIDLIDRLHKQEGTTTIIIEHRLEDVLYRQVDRVVL
                     INDGRILFNGGPDDLLRTSLLQENGIREPLYLSTLRALGYPIAQAERLSSVWEIDIEA
                     LNIASLPTLHFENGEKEALLEVKHLYFSYPNKQVLTDIQLTIHKGERLAIVGKNGAGK
                     STLAKVLCGFIQGEGEILWKGQSIKEDSVKERAERIGYVLQNPNQMISQTMIFDEVAL
                     GLRMRGVTEEEIEHRVHHILKVCGLYPFRNWPISALSYGQKKRVTIASILVLNPEIIL
                     LDEPTAGQDQRHYREMMEFLDQLNAQGHTIVMITHDMQLMLDYSDRAVVVVDGQIIED
                     ASPAEILSDDTVIERANLKETSIFHLAERVGVNPLELTTFYMQEERRGR"
     gene            complement(22440..22682)
                     /locus_tag="AC1PIV_000750"
     CDS             complement(22440..22682)
                     /locus_tag="AC1PIV_000750"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HIP6611787.1"
                     /translation="MPKGGNLILMQADSFAQRVPFQVVASGNEVLISLNVASREEVDR
                     IIERVEANGGQITGCPTDARGFYGASFTDLDGIILM"
     gene            complement(23009..23992)
                     /locus_tag="AC1PIV_000751"
     CDS             complement(23009..23992)
                     /locus_tag="AC1PIV_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HIP6611788.1"
                     /translation="MSKDIRVLLYYKYVPIENAKEYAAEHLAFCKSIGLKGRILIADE
                     GINGTVSGDYETTQKYMDYVHANPLFSDLWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDIDPLVTTGAYLSPKEFKEALLDEDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVRGELWDGKMYVFDERIAVDVNHVNPVVVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEHKYVRGCSAECRAHERNRYISENGLTRQEWAERLEAIGETLTPANA"
     gene            complement(24205..25125)
                     /locus_tag="AC1PIV_000752"
     CDS             complement(24205..25125)
                     /locus_tag="AC1PIV_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611789.1"
                     /translation="MVWTEEKLGPIIHSILNPDEEVLSLYQSKTTKSIYGCILWNNYY
                     YKVFRVSNHPSQSTYKQPTFYDFHGEFYMKGAIRTYLYHTNSWYELSKQGYYLLLFFQ
                     KLWDEKQEVEASWQNGRMQIRLVVEEEGWQVHYRFPDNQAREVERLLGSGMLVAIRSS
                     RNFIKIRTSRFVAPYIALIKQRQLYRKKPSKAMLQWEKYQSQLIEIQRTYRLVEESAP
                     QTFFGHWLNKVQLYLCSAIASYWEEVIKGVEWQEAREIKEQRKAEKPHNPIEDKWKEN
                     IARRHKRKMDQLIGHDTLEKLRQLKTELDD"
     gene            complement(25233..25778)
                     /locus_tag="AC1PIV_000753"
     CDS             complement(25233..25778)
                     /locus_tag="AC1PIV_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HIP6611790.1"
                     /translation="MKNNSIKTVVATGIGAALFVVIGHLINIPTFVPNTSIQLQYAVQ
                     SLLAVVFGPVVGFLVGFIGHTLKDSLTYGPWWSWILASGVFGLVVGLTKKRLRIQEGI
                     FEGKDILFFNLVQIAANVLAWGVIAPVLDILIYSEAANKVFAQGLVAGIANSITIAIA
                     GTLLLVVYAKSQTKTGSLSKD"
     gene            complement(25799..26647)
                     /locus_tag="AC1PIV_000754"
     CDS             complement(25799..26647)
                     /locus_tag="AC1PIV_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SAM hydrolase/SAM-dependent halogenase family
                     protein"
                     /protein_id="HIP6611791.1"
                     /translation="MSNNLLVLQSDFGLVDGAVSAMIGVALQESRDLVVHHLTHDITP
                     YNIFEGSYRLFQTVEYWPEGTTFVSVVDPGVGSKRKSVVALTEQNHYIVTPDNGTLSF
                     IKKYVGIKAVREISEVANRRANTEHSYTFHGRDVYAYTGAKLASGHISFEEVGPELSV
                     DKIVEIPTVPTEVGSDYVKGAIDILDVRFGSLWTSITREEFYTLQPQFEDRFEVTIYN
                     NDMLVYQNQVTYGKSFADVRIGQPLIYINSLYRVGVAINQGSFAKAYNVGVGQNWHIE
                     IKRISN"
     gene            complement(27011..27727)
                     /locus_tag="AC1PIV_000755"
     CDS             complement(27011..27727)
                     /locus_tag="AC1PIV_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HIP6611792.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPETN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFVEGRYEGFGPNGSMIIVDTLTSN
                     VNRTAANVRSAFGKNGGNMGASGSVSFMFDKKGVVVFAGDDADAIFELLLEADVEVDD
                     VEAEDGTITVYTAPTDLHKAIVALKESGIQEFNVTELEMIPQSEVSLEGDDLATFEKL
                     YDALEDDEDVQKIYTNVDGF"
BASE COUNT         8031 a         6462 c         4992 g         8331 t
ORIGIN      
        1 aaagtagcct aggaaacgaa gtcgaagata gaactggagt tcatcaaggc aagttgacaa
       61 cggataattt tgattttcga agagtataaa tgagctttaa tttgatctag catgactttt
      121 ccccttttat ttttagtgta acataaaaaa actaacccat cacaaaatgt gataggttag
      181 ataacttaat gacattgggt atctccccaa ccttattcat ctttattgtc cgctacctgt
      241 tgaagtactt gtacttgtgg aacttcctgc tgaagaatcg ctactggttc tggttgatgc
      301 aacagagaca tacaaggtaa ctgttccatc aattgttgct ccagcagcag gatattgtcc
      361 aatgacgatg tcacttgtcg ttgaataata gcttctatct tcttgttttt caatactttc
      421 cgcattgaca cccaaggctt gtaattgact acgcgcctgt gaataggtgt aattgccaga
      481 tgttaaatca ggcataatca attcttttcc ttttgaaata actagattga tgatagaacc
      541 ttttgccaac tctgtattgg caacgggatc tgtgctgata acctgacctg cagtaacaga
      601 tgagctatat tcctgagtaa tggttccaat gctgaagcct gctgtctgaa gaatttgagt
      661 agcattctcc tgactttttc caacaacgtt tggaacaact tgtggcgcca ctcctttgga
      721 aacgtaaagg gtaatttttg cacccttctc agcagaacta tttgctcctg gatctgtttt
      781 gataacgagt ccttgggcaa ctttttcgct atattcttct tttattgtca cttggaaacc
      841 aagggcctcc aattcctgcc gcgcagtatc agactcctta tccaccacat ctggaataga
      901 tgccagcgca gccgttgcta ctacaatatc aatcttactc ccttgacgtc tggtcgtctt
      961 tgcagccgga gaggtccgta ttaccaagcc ttcatctaca gtcgctgtcg cttcttctgt
     1021 gatatttcca acttccaatc ctgccacttc aatcatttct gtagcttttt caacggtttg
     1081 accagataca tcagggactg taactgttcg tggagtgttg aaaaacatga gtccagccgc
     1141 tatgactgtt aacaaaatag ctcctatcaa gactttgtag cgtgtacgta tgcctggcct
     1201 tggttttgaa acaggcttat ttcccgactt cgccacttct ttcttaccag accccttatc
     1261 cgtcgcagaa acttgagcag aactgtttgt atgcggtact ttcgtttcaa cattggcttg
     1321 ggagagtttc ggcaaggttt ttgtatcaac cttgttccct tctagttcaa ccctgggttc
     1381 attctgacga tccatggata gagccgaagc taaatctgca tacatttctg caaccgactt
     1441 atagcgctcg tttaattttt ttgccgttgc ttttagtaca acattttcta aggcctgagg
     1501 tacgttggca ttctcttctc taacagatgg gagaggtttt tggaaatgct gaagagcgat
     1561 cgtcacagca ctgtctccat catagggaat gcgacccgtc aacatttcaa aaaggatgat
     1621 tcccatcgca taaatatcac tttgaatggt cgctttcgaa ccacgcgcct gctcaggtga
     1681 aagatagtga acagaaccca acatggagtt ggtttgtgtc aaactcgttt cagcaaaggc
     1741 aactgcaata ccaaagtctg ttactttagc gactccattg gaagtcaaaa ggacgttctg
     1801 aggtttcaaa tctcgatgga caattcctct cgtgtgcgcc atgcgcatag caaggagaat
     1861 ctgtcccata attcgcaccg caacatcgtt ggaaagtggt gcattttctt ttatataacg
     1921 ttttaaatcg aggccattga catattccat agccagatac tgttgaccat cttcttcacc
     1981 gatgtccgaa atacgaacga tattgggatg gtcaagttct gccatggcac gcgcttcacg
     2041 ttgaaaacgc tggatagcaa tttgatctgt ctgatagttg gtccgaagaa ctttaacagc
     2101 aacctcttct ccatctaaaa tcaaatctct tgctaggtaa acatctgcca taccgcctcg
     2161 accaatttgc cgaacgattc gataccgacc ggcaaagatc ttaccgattt gaatcattac
     2221 ctagcctcct ccgtaatgtg aagcaaacct actgtaatat tatctagacc gcctgcatta
     2281 ttggcaaaac gtacaagtgt ttctaccttg ctttcaattg aaacatcact caatacaata
     2341 tcacgaatgt cctcggttgg tatcatattg gttaagccat cgctgttaat aaggacataa
     2401 tctccaacct caagagtttt caaagcaatg tctggttcaa ttggttcggc ttgtccaatg
     2461 gactgcgtta caatattttt ttgaggatga cgctgtgctt cttcttctgt gagctgacca
     2521 gctcgaacaa gggcacctac cagcgaatgg tcgttagtta gacgtgtata ttcgccatct
     2581 ctaatcaatc caactcgtga atctccaaca tgggcataga tcatttgatt gtcgatgaca
     2641 acaactgcct caagagttgt tcccatcccc ttgtattctt ctgtctgtcc aagttcatga
     2701 atcttttggt tttcagcatc aatgattgca accatccatt cacggacatc attcaaagtc
     2761 actaattgag tatcaaccca agcagctccc aaatctgttg ctgccatctc actagcaata
     2821 tggccggcac ggtgaccacc cattccatca gctaacacga ccaaatcaat ccctgcgcgg
     2881 tttttgtagc gattgatata gtcttggttg ttcgaacgtt tctgtcctac atcagtaagt
     2941 aatgcaattt ccataatttt tatcgttgct aagcaacttc ctcctcttat tctaggattt
     3001 tcgtctaagt tgaccgatga aaaagccatc tgtcttatac tgttcagggg ttatcaacaa
     3061 gcaaccatcc accataatat ctgtttgagg gtgttctagt gtcacctgtt caaaattggg
     3121 atggttttgc agaaattctt gaataacctc ttggttttcc ttagcaataa tcgtacatgt
     3181 gctataggtt attataccac caattttcaa gctttggcaa acactgtcca gtatctgcaa
     3241 ctggatagtc tttagagaat caaaatccat cgatgcctta ttataacgaa tatctggctt
     3301 acggcggatg agtccaatac ctgaacaagg ggcatccact aggattttat caaaggtatc
     3361 tggaccaaat tcctcatgaa cacgactggc gtccagacct ttggtctcaa tcttatctgc
     3421 taggcctaaa cgacgtgcgt tttcttcaat caggtttagt ttatgatcat ataaatccaa
     3481 cgcataaact tttccatccg taagatagct tgccatatga caggtctttc cacccggagc
     3541 cgcacaggca tccaagatga tttcatctcc ttgaatatcc aaagtcggag ctaccaattg
     3601 actggtttca tcttgaatag tgatgagtcc ttccttgaaa taatctgtcc ccgcaaagtg
     3661 tccatgaggc ttaaccaacc caactggtga taactgcgag tgttgagcgc ctagctcctc
     3721 tgccaatcgc tccacttgtt gaccatctgt cacacgtaca ctggccttat tccgatcatg
     3781 taaactttgg aaaatcttct ctgcacgttc atcgccatat tctgcaatca gggtttggac
     3841 caaccaaact ggcacagaat actgaacgga tagacgtttg ttctttcttt taatatctgc
     3901 tggtttcggc aaggaatcct gactaagctt acgcaaaatg gcattaacaa atttgtcagt
     3961 tccaggcttt cgcttggcaa tattaactgc ctcattgaca actgcgtggg taggcaattt
     4021 gtccaaatat accaactggt agaggctcaa catgaggaga tagtagaccc aagtgtccaa
     4081 cttttcccta tcttcgataa aatgtgccaa ataccactct agggtaattt tacgagaaac
     4141 cgtcccataa accaattcgg tcgccaagcc cttgtcctgt gctgataaac gagaagattc
     4201 tagagcctta ttgagagcga tgttcgagta agcaccttga tcaaagactt gttccaatac
     4261 agataaggct agacttcttg ctgtttcatg tttattgatc accaaattga tctcctactg
     4321 caatatctcg acctgcacca tttaaaaagt ctgcaatggt catttttggc ttaccagctg
     4381 gctggacagt tttcagagaa agggctccct gacctgtcgc aatgatcaat tctttcttgc
     4441 ttcgagcaat aacccgacca actgatcctt caccttctgc ttctacagct tcttgaattt
     4501 taaaccgttc gccttgccaa taggtgtggg caacgggcca cgggtacata ccgcgaatct
     4561 gattaaatag ttgacgagct gtcttattcc aatccagtac ctcttcttct ggctggatat
     4621 ttggtgagaa ggttacctgt tctggatttt gagcgactgg tttcaagtca ccagcaatat
     4681 aggctggtaa ggtttgtaat aataaatctc gaccaacaac agccaacttt tcaaacaagg
     4741 tgccgacatt gtcgctttct tcaatagcaa tgctatcgct ggaaatcatg tcaccggcat
     4801 ccatttcctt gaccatttcc atgatggtta caccggcacg ttcatcaccg ttaatcaaag
     4861 cgtaatggat aggggcaccg ccacggtatt taggaagaag agaagcatga acattgaccg
     4921 caaagtcaac tgagttcaat aatttggttg gtaggaattg cccaaaagct gccgtcacaa
     4981 tcccatctgc tcctaaattc atcagctcat ccatttcttg acttccagat agcttctctg
     5041 gttgatagac tggtaaattg tattccaagg ctacttcttt cacaggtgtc atttggatga
     5101 ctttttttcg tccaacagct cggtctggct gggttacaac tgccagtatg ttataattcc
     5161 catcagctaa gagccctctt aagaccgtcg ctgaaaacgc tggcgttccc ataaaaatca
     5221 actttgtcat attcgtgttc tcatctcctt ttcattttct gattcatatc aattatacta
     5281 tcccctaatt atatcatttt tgcttatttt ttccttaatc aaaggttctt aaaacaaaaa
     5341 aatgcaaggt caatagtgac ctcacatcat attctgcggt tcattgtcaa taatcagtcg
     5401 caaatcttga ttttctctct cctgtgtcca atccaaaatc tgattcaata cctcttccaa
     5461 acggtcttca tgccggtatt tcaagatgat ctggtagtgg tagagattat gagttctggc
     5521 aataggcttg ggcgtcggtc ccaagatttg aattgcatct gttaagtgtt gacggagaaa
     5581 ggctacagtt tcataggctt ttttcacgac aaattcttct gacttgtgcg aaaaggttag
     5641 acccaccgta aaatagtaag gtggatagcc aagatttttc cgaatgtcca tctcataacg
     5701 atagaaacct tcatagtcct gctctttggc aaaagcaatg gcataatgat tggggttata
     5761 ggtctggatc aggacctctc cttccttatc agctcgacca gcccgaccag ctacctgagt
     5821 tagcaactgg aaggtccgct cagaagaccg aaaatcaggc aaattcagag ccgtatccgc
     5881 attgagcacc ccaactaggg tcacatttgg aaaatccaag cccttggcaa tcatctgagt
     5941 tcccagaaga atatccgctt cgcctcgacc aaaccgttcg agcaagtcct catgagcacc
     6001 ttttttcttg gtagtatcca catccatacg caaaattcta gcttctggca agagctcctg
     6061 caattcatcg taggcctttt gcgtacccgt cccataataa cgaatagaac gactttgaca
     6121 gtttggacag gtctgaggaa tccccttttg aaaaccacaa taatggcaat tcatcgtttt
     6181 tgtatccatg tgaagcgtta gggaaatatc acaattggga cactggtcaa cactcccaca
     6241 atcacgacac atgacaaaag aagaataacc acgcctattc aacataagaa cgacctgttc
     6301 cttacgagcc aatttttctc ttatcttttc aatcagaaca ggggtaaaat tactagcctc
     6361 ctgctgaccg atataatcac ggaaatccac aacttccact tctggaatac gagccaaggg
     6421 attggccctc tggttaagag tcagtcttcc atagactcct cgactagccc gagcccgtgt
     6481 ttcaagactc ggcgtagcag accccaagac cagggtcgct cgattatagt ctgcccgcaa
     6541 ctttgccaca tcacgcgcat ggtagcgtgg attgctgtcc tgcttgtagg tcgcttcatg
     6601 ctcctcatca atgatgataa cacccaagtt tgtcaaaggg gcaaaaatgg ccgaacgggc
     6661 cccgacaacc acctgggcat tccccgcctc aatcttccgc cactcatcat acttctctcc
     6721 atcagacaga ccggagtgaa gaatcgcgac ctgctgacca aaacgagaaa taaaacgatt
     6781 ggtcatctga ggggtcaagg aaatttcagg caccagcata atagccgttt tccccatctt
     6841 caagacccta tcaataacct ggagatagac ttccgtcttc ccagaacctg tcactccttg
     6901 cagtagaaat gtctgacttt cctgaccgat agaggctaca atctcccgaa ccgcaatggc
     6961 ctgctctgga ttcaaatcca aggcctgcgt tttttctacc ttatcaaaaa caccctgagt
     7021 ccgcgacact tcctcttccc agacttctat atagcctttt tcttggaaat agcggagcgt
     7081 atcagctgaa tagtccgatt ttaggtttga aaggagctgg tcttccgact gttccagaag
     7141 aaattccctt aactgctgcc gttttttagc ccgattgctg atgtctgctt ctcgtaattt
     7201 ctccagacaa actcggtacc atttttctgt cttgatttgc ttcttatcct tggccacata
     7261 gtctaccaag atttttcctg actgggccag acgcatgatt ttcccttgct ctgtcacgtc
     7321 caagtcagaa aaacgaatct gctccttatc accaaacaga ctaatctgct ctgccatttc
     7381 caaaccaatc cctggacgga tcaatttgtc ataggtcgaa ttgagcaagc tgggtagcat
     7441 ggattttaag agagtaattt tataggagaa gaccgacttt ctcatctggt ccgccaacca
     7501 aaattgctct tgattgagaa caggactata gtccaaaacc tcggcaagct ctttcaagtc
     7561 ttgtaagcta ttttcatcat cttcatcaat caaatcaact acaatccctt gaatcagccg
     7621 atttccctta ccaaagggta catggacacg cacgccaacc ttgagcccct cttccaactc
     7681 agctggaact cgataggaat aagcttgatc tgtctgcatc aaagggacgt ctacaataat
     7741 ctgtgctaac ataccatctc gatttatttt accttctaat atcacgactg atgcgaacaa
     7801 ggttcacttt atgtataacc ttcaactatt agttggagca aatattaaaa gataaactaa
     7861 atgacctgcc tcctttctgt caaaactttc atcattccga aagtgaaaag aaacccggat
     7921 ggcaatccca accgagtctt gtatctaaat cttttcgcct tcttcttttt ctttagcaat
     7981 ttgagctttg attttacgct cttcttcttc cgccaaacgt ttagcctctt cggcacggcg
     8041 acgaacagcc tcacgtttcg cttctgggtc tggatggatg actacattac ctgattcaat
     8101 ttcttccaag gcgcgtaggg tggatttcac tgaggtgaat tcttgagttg gtttggcacc
     8161 tgcttccaat tcatgggcac gcttagcctc aagaataacc aaagaatact tagatggtac
     8221 cttatccaac aaggtatcaa ttgacggctt caacatcata atgcgattct ctcttctttc
     8281 ttttatcgtt ctactatctg ttcacgaatc atttcatcgt agcgaccaat cactcggtct
     8341 acacggaaat gttctgcttc gattatacgc ttgacacgct cagcagccaa cggaacttca
     8401 tcgttcacaa ctgcataatc atactcacgc atcaaggcaa tctcttcctt ggcacgttcg
     8461 atacgttgag caataacttc ctcactatcc gttccgcgac caatcaagcg atcttgcaac
     8521 tcctccaagt caggtggtgt caagaaaatg aacaccccat ctggaacctt tttcttcact
     8581 tggagggcac cctgtacttc aatttctaaa aagacatcaa ttcccttatc aagagtttca
     8641 ttgacatagg tcagaggtgt tccatagtaa tttccaacgt actctgcata ttccaacatt
     8701 tgaccctggc gaatcaaatc ttcaaattcc tcacgactac ggaagaaata gtcaactcca
     8761 tcaacttctc ccggtctctg tggacgtgtc gtcatggata cagaatattc aaatttatta
     8821 tcagagcttt caaaaatttc ctttcgaact gttccttttc caacaccaga tggaccagaa
     8881 aagacaatga gtaagcctcg ctctttcatg atatctcctt ttaaatcttt cattctagtg
     8941 taacaaaatt tagcatgaat ttcaactgct tttaaatacg attaaaatat tttctatttt
     9001 ctattcccaa cccaaaacga actttgagcc agtagaaaaa gagcccttcg gactcttcta
     9061 catttactta gcaacatctg ttgctcttgt ttcacggata actgtgattt tgatatttcc
     9121 tggataatcc agattatttt caattttctc acgaacatca tgggccaaga tggtaatctg
     9181 atcatcagtg accttgttag gatgaacgat aatccgaatt tcacgaccag cctgaatagc
     9241 ataggattgt ttaatccctt caaaactgtt ggcgatttct tccaagtctt gcagacgttt
     9301 gatgtaggct tccatagatt cacgacgtga acctggacga gcagcgctca gagcatctgc
     9361 cgcagccaca atgactgcaa tagtacttgt tgcttctaca tcgccatggt gactagcaat
     9421 cgcattgata acaattggat tctctttata tttcttagct aattctgtac cgatttcaac
     9481 gtggcttcca tccacctcac ggtcaatagc tttaccaacg tcatgtagga aaccagctcg
     9541 acgtgccaaa ttcacattct cgcccaattc agcagcaagt acacctgcta atttagcaac
     9601 ttcgattgag tggcgaagaa cattttgtcc ataagaggta cggaaatgca aacgccccat
     9661 gattttaatc aagtctggat gaaggtttgg tgccccaact tcataagcag cagcttcccc
     9721 gtactcacga atacggttat ccatctctac acgatgtttc tcaaccaact cctcaatacg
     9781 agctggatga atacgaccat cttgaagcaa ggtctccatg gtcatacggg caatctcacg
     9841 gcgaatcgga tcaaaacctg atagaacaac cacttctggt gtatcatcaa tgataacatc
     9901 gatacctgtg agactttcaa aggtacgaat atttcgaccc tcacgtccaa taatccgtcc
     9961 cttcatcgca tcatccggta aatgaaccga tgtaatcgtc tgctcagcca catattcacc
    10021 tgatatgcgt tgcatcgctt gggctaacaa gtcctttgcc attttgtcag aacgttcttt
    10081 tacttcacgc tctgcttcct tgatacgagt cgcaatttca tgcgtcagtt tatcacgtgt
    10141 atcggtaagg atgatttcct tcgcctcttc ttgactgagg gccgccactc gttctaactc
    10201 caaagctttt tgttcttcga gttttacaac ttcttgttca cgctcatcaa tgtgcttagc
    10261 tttatcggtc agactttgtt ccttttgttc caaagtcttt tccttgttgg tcaaattatc
    10321 gtctttgcgg tccaaactgg tcgcacgctc tgtcaagcgt gattcgattt gcttcaactc
    10381 ttgacgttct gacttaaatt cttctgcaat ttcttctcgg tacttacgag cttcttcctt
    10441 agcttccaag agtaattctt ttttcaaggt ctggcgatcg cgctcagctg tttttagaat
    10501 aacctcagct tgctcttctg ctcgaccacg aacattacta gcttcttgtt ctgcgtttaa
    10561 aagtgtcaat tctgcagttt cttttgcaga tttcatcttc aaagaaatgg caaagtaacc
    10621 taatactaaa ccaatgagag cagaaacaag tgtcactact actgtaatga tattcatatt
    10681 tctacctctt tttttataat tcgattttca caaaatctgt atctatttta tcatatttga
    10741 aacgatttca caattccaaa ttgtcaaata tggtataata aattcatcac ttatttggag
    10801 gaaaccatga aaaaagaagt cactgtcgaa agcttcgagc tagaccacac tattgtaaaa
    10861 gcaccttaca tccgcttaat ttctgaagaa gtcggaccaa aaggagacat tattacaaac
    10921 tttgatattc gccttatcca acccaacgaa aatgcaatgg atacagctgg tctacatacc
    10981 atcgagcatc tattagctaa actaattcgc cagcgcatcg atgggctaat cgactgctct
    11041 cctttcgggt gtcggacagg tttccacatg attatgtggg gaaaacaaga ctctgaaaag
    11101 attgctcaag tcatcaagtc gagtttggaa gaaattgcag aaggcatcac ttgggaggat
    11161 gttcctggga caaccattga atcatgtggt aactacaaag accacagcct tcattcagct
    11221 aaagaatggg ccaaactaat cctttctcag ggaatctcta cagatgcctt tgaaagaaaa
    11281 ccaatctaac aaaaaaagcg gatacaccgc tcagaacgta gacaaactcc taaaaatata
    11341 taaaattgaa gaagtttgcg aaagatagca aatcattaaa ctcttagaaa cattgatatt
    11401 tcggcgtttc tgagagtttt tttatagtcg aatgaattag ctttcagaca aggaaccgag
    11461 gtgcaggttg ctagcacagc ctagtggctg tgctaggttg gagatataac ttgcaaagca
    11521 agtcacttct gcagagtacg gcaagccgaa agtgacgatg tatcaaagtt aattcaaatg
    11581 actatatttt caacacaaag aaaaaagatt gaaggaaatt gtccaaaatg aactttttct
    11641 tcaatccgaa gcagataaac cgcttttttg tttaataatc caaggcatca gaatgaccag
    11701 caccattacc gacaaagtag cctgtcttac aatttataga gaacaagtag gtcccatctg
    11761 gtttaaacat attgtagtag ccattgccgt tgataatatt aactttttcc aagatatatt
    11821 gattgcctgt tatataccca cgttgttgcg agatagtcac aatattttca agaatacctg
    11881 gattgaaatt ccatgcttca ttgtttacat catcaatcat cgcttgatta taaggaacac
    11941 gactgcggtc acgttgcaag acgacaccag ctggcacggc aataccaaag tcggttgttg
    12001 agcctgaaac cgttgttgaa gcgacttctg ttgtcgctgg tacaccagta gatacagttt
    12061 catcagcacc ttggtttctt gtaactgcag cctcacttgc taccgtagcc gaagcgactt
    12121 cctgttgtga acgaccaaaa ttcacgaccg atgccaatag actgtcaacc gcactaatcc
    12181 ctgtcgttgt cgcagaaaga gattctcctg atttaaccgt cgccgttgta tcaatttcac
    12241 cattaacaac gacttcttta tcaaactgac cattaatggc ctgaatggct gcaatggctt
    12301 tttcaagatg atcatactgt tctttagctt tggtataact gtccgaattc ttatccaatt
    12361 tttccaacag cactttcagt tctgctaatt taccaaactc tgaatttttt agcttggtca
    12421 aactactatc cgtaaagaaa ctattataga gctgttcaaa agctgtcaca ttcgcatctg
    12481 tcgaacttga tgctgttgat gacgtctggc ttgtacttgt tgaacttgaa gaagtcgcag
    12541 tattcgattt gttaaccgaa ttcatccaaa ccagcgccgt cgccattaca ccaatcattg
    12601 aaagccctac tgctgaccag aagtaaaatt tctttttctg atccctatct gcgccctcac
    12661 tatggtccaa gtcttcggtt tcatcttctt ccaattctaa actagaatca tctgccactg
    12721 aagataaccc ctccattgct acggtacttg caatcactgt ttcttccaag gtttccatcg
    12781 gagttaccga aagttcttct acaataggag caatctcctc actaacttcc gtaagagaag
    12841 actcatttgc ttctacctct tccgcgcttt catgtccttg atttttttcc tcatcagcca
    12901 cctcaactaa aggaagatga ttgattttgg tttcaaattt ttgagattca atttctgcgc
    12961 ggtgttgctt gatgtaacga tccaagagac catcatcttc tgtcacaccc gcttcaatct
    13021 ccttatgttt tttgactgct tcttcgattg ttaaatcttt cgccacttca aaatctaaaa
    13081 ctttctcctc atccaaagga agatgatgac tatttttttc tcccacgatg tcctcctatc
    13141 cttgcacttc ttgcacttga cgtttcactc gttgaccaaa aaattgataa agatccactt
    13201 ttagggtccc attatacagt ttgcgcttct tatccgcttg ctgtccaaaa cgggtttcaa
    13261 acaactcatc actagttaga ataaacttag accatgtttt gagtggttca aaagtctccc
    13321 ccatttctcg atacagggta acaatggctt catcatccaa caaacgttct ccgtaaggtg
    13381 gattagaaat aatgacacca ttaattttat ctgtacgcaa gtcttgcaca cgcatttgct
    13441 tgaaaacaat atcctgctca actcctgccg caaatgcatt cttcttcgca atttcaatca
    13501 tacgagcatc aatatctgat ccagtaatat ctaataccaa atctgttttg atagaagctt
    13561 gtgcttcttt gcgtaatgca accaccaatt gatcctcaac ccacggccat tcctcaaatg
    13621 caaaacttct cttcaaacct ggggctatat ttttagccaa catagctgcc tcaatacaga
    13681 aagttcccga tccgcaagta gggtcaataa gcggtttatc tggataccaa ttcgataatt
    13741 gcaaaatagc agctgccata ttttctttga ttggtgcgcc acctttttcc acccgataac
    13801 cacgtttgaa caaactagaa cctgtcgtat caatcatgac tgtcgccaca tctttcaaaa
    13861 tcgacacttc aattttaaac tctgccccca tctcttgcaa gggaacccct tcgggacgag
    13921 agaagtgttt ctgcagtttc tttacaactg ctttcttaga aatagcctgc acacttggtt
    13981 cattatgcaa tttcgatttg acacatttgg ccttggaaat ggggaacttg cagcctagag
    14041 gcaagtaatt ttcccaatcc aagttaaaaa ctccttggaa caactcttca aaagtctttg
    14101 ctggaaattg tccaacaatg attttaattc tatctgctga acgcagccag atattggttt
    14161 cgataatgga ttttacatct ccttggaatc taacacggcc attttccact tggcattcat
    14221 agccgagatt acgaatttct cgacccacaa ccgcttccag accagctgct gccgttgcaa
    14281 tcaactcaaa ttgttttttc atttttttcc tctacaataa aagctagcag agctagctac
    14341 ctattttatg caattttctg taagccatgt tttgttccag tggtactagg ttctaccacc
    14401 ttcgataatc atctgtctac tgtctaaaca gtcaggattt ctgttcattt ccatccatcc
    14461 catgccccga ccaaagtttg ggttgctagc ttgaggggtt taccgcgttc cattttttac
    14521 gtttccataa aaacttcgtc actgtggcac tttcagatct actctgacat atcaaaagac
    14581 ttagccattt taaccgccgt aacgcccaag ggcgtcccta ggcttattga ttcgcctagc
    14641 acaaacacta ctggcatctc agccagtgct agcatggact ttcctcatgg tagaaaacta
    14701 ccacgcgatt atccaaaaat tgcaccttaa ttatcttaga agttgtatct acaaagcaag
    14761 ccactttaaa tcaaggaata tctctgacac aaatacagaa tgtatttgtg cacaagaaaa
    14821 taactgcgaa taaagtgtca gtttaggtgt acaattttct attcttgatc ctgaacgatt
    14881 tgttttccaa atacttcttt ctccagacga ttcagacggc ggagaatatc aaagtttgtc
    14941 gctgaagatg gacgttctgt acgcaataca tcgttcgatt cttcagtagg aagagttgtt
    15001 ttgggagaat ttgctgcctg cgctttcaat cgagcaattt cgccttttaa ttccttgata
    15061 atcgcttcat aagcatcata gtctttcata atatcatcaa gaaaatcgtt cacttcatct
    15121 tgatcatagc cacgaaaacc aattttaaaa tcttgctcga aaatatcttt tgtcgtaaat
    15181 ttaatacttg ccatctctct ctccctaatc taaaacgtca ctactcctat tatattaaaa
    15241 aaaataggga aaaatcaagt caaatcactc agaatttgaa aaattttcag cctcctcatt
    15301 caattcctca aaggtaagcg tttttctatt atatccttct ttctttaaga ccatgtgata
    15361 taaatatttc aaattggttt cattttcaga atcgtaaaac aaataacaac ctgtcgtatt
    15421 atccagtaaa aactggttat agtctctaaa ttgccctggg ttttcatagc gtggataggc
    15481 atactttaca aaatcaacct gcttaaaccg tgctaacttt gcttggttag cctcattcca
    15541 ctgttcgcca tgattttcaa atggaaatat tgttgcaata ctcagttgat acccctcggc
    15601 tcgcaaatct tctaagactt ctaaggacca gtattcaaaa cccaattgac ctgtcagtat
    15661 aaaccaacta acaccctctt ctaaaaaacg aataaaattc ctacgaattg cagatttaat
    15721 aatgtgcagt cgaggatctt tttctgaaaa aattcccagg tctgtatgtc tataacctgt
    15781 taccaaaagg ctcttagtat ccatttcttg tactcttttc gctaattatg gtataatatg
    15841 ctgatattat tttatcaaga aggagttcta tggtcaatta tcctcataag gtgtcaaaaa
    15901 aaatcaatag aaccagtcct atttcatccc agcgagtaaa ctttgctaat cgcggaatgt
    15961 cttttgaggc cgctatcaac gatagcaatc aatattacct tgcgcacgat attgctgtca
    16021 ttcacaagaa gccaactccc gtgcaaattg taaaagttga ttaccccaaa cggagccgtg
    16081 ctaagattgt cgaagcatac tttcgacagg catctaccac agactactct ggtgttttta
    16141 aaagacatta tattgatttt gaagcgaaag agacacgcca aaaagcatcc atgcccatga
    16201 aaaattttca tgcgcatcag attgaacaca tgaaacaggt tgttaaacaa ggtggtattt
    16261 gttttgtcct tcttcacttt tcaacattaa aagaaaccta tctcttgcca gccactcatt
    16321 tgatcgaatt ttatcaagta gacatgggta gtaagtcgat gcctctaacc tttattcgac
    16381 aatacggctt tgagattcaa atggggcgtt tccccagcat cccatatctg gaaatcgttg
    16441 aaaaaaatct attaggtggt gaatcttttg aaaactacaa caattaaaaa agctcttcta
    16501 atcactgcaa atattttact tgcgggggct atcattgcct gcctggccgg agctgcattg
    16561 gttgtttact acatccaaag cgctccagaa ttgacagaag aatctttgac agcaactgtg
    16621 tcaagtaaaa tttatgataa gaacggaaat cttattgcag atttaggagc agaaaaacgt
    16681 tcgagtgcca agactgaaga aattccaaca gacttggtaa atgcgattgt cgcaatcgaa
    16741 gaccaacgtt tcttcaatca tagaggagtt gacgtgattc gtattgcagg ttccctgatt
    16801 aataacttga gcggaggacg tttgcagggt ggctcgacac ttgaccagca gtttatcaag
    16861 ctgacttatt tctcgacatc cgtagaagat caaaatctaa aacggaaaat tcaagaggct
    16921 tggctagcta ctcaattgga acgtcgcaat accaaacaag agattttgac ctactacatc
    16981 aacaaggtgt atatgtcaaa cggtaattac ggtatgaaga ctgctgctct tgctttttat
    17041 ggaaaagagt taaaagattt gactcttcct caattagctc ttttagcagg aatgccccaa
    17101 gcgccaaacc aatatgatcc ttataccaat ccagaagatg caaaagcacg tcgcgatttg
    17161 gtattggctg agatgctgga agaaaagtac attgataata cccagtatga acaagctgtt
    17221 ctaacacctg taacagatgg tttgcaacca ctatctaatg cagctgctta tcctgcttat
    17281 atggacaact atctgaaaca agtcgttgaa gaagttgaag caaaaacagg ttacaacttg
    17341 ctgacaacag ggatggatgt ctatacgaac gtcgatcctg ccgcccagca gcaactttgg
    17401 aatatctaca atacagatat gtatgtcagc tatccagatg atttattgca ggtagcttca
    17461 acggttgtgg atgtttctaa tggtaaagtc gttgcgcaat tagggggtcg taaacaagaa
    17521 acaaacgtct catttggtac caaccaagcc gttgaaacca accgtgactt cggttctaca
    17581 atgaagccaa tcacagacta tgctcctgct tttgaaaacg gcatttatac atctacagca
    17641 gatttaatct tagacggtcc ttataactat cctggtacac caactcctgt caataactgg
    17701 gataaacaat actacggtaa tatctctgtt aagactgcca ttcagtattc tcgaaatgtt
    17761 accgccgtta aagcattgga agctacgggc ttagaaaatg ccttgaaatt tttgaatagc
    17821 gttggtatca attatccaga tattcattac tctaatgcta tttcaagtaa tacatccgat
    17881 actagcagta agtatggagc aagtagtgaa aaaatggctg ctgcctacgc tgcttttgcc
    17941 aatggtggta cttactacgc tccacagtat gtcaataaaa ttgtctttag tgatggaaca
    18001 gtaacagaat atgctcctaa agggaccaaa gtcatgtctg ccgaaacagc ctacatgatg
    18061 accgacatga tgaaggctgt tatgtcttac ggttatggat taaacgcttc tgttagtggt
    18121 gttcctatgg ccggtaaaac aggtacatca aactataccg atagcgaaac ggatactatt
    18181 ctagcttcaa ttccagaagc aaattatagc tacatggtcg ttcctgatga aaacttcgtt
    18241 ggatattcta gtcagtacgc aatggctgtt tggaccggat ataccaatcg tatgactcct
    18301 atccttgata acagcatgcg aattgcaaca gatgtctacc acaatatgat gctctttatg
    18361 cattcggact atacagctac cgattgggag atgccaagcg gactcgtacg ttacggttcc
    18421 aactactatc tcagaggtag tcgctcactc tccaatgctt ataatactta cactagctct
    18481 agtacaagtt cttctagttc gactgaaact agtgaaacaa ccgaagcgac gacaacatca
    18541 agcgaaacat catctggaac tgcaaccgag actgcaactt cttcaactga aactgcaaca
    18601 acaggaaaca atcccgcaac gggacagaca gatggtcaat aagaaaattc ccagactctt
    18661 ctgggttttt cttttgctta aattatgata agataagatt atgaaacctg aagtatttta
    18721 taaaaccttg gcagaccaag gtattcaatt aactgaccaa caaaaacacc aatttcatcg
    18781 ctatttccaa ctattagtgg aatggaatga aaaaatcaat ctgacagcta ttaccgagga
    18841 aagcgaagtc tatctgaagc atttctacga ttctatcgct ccactcctgc aaggccatat
    18901 tcagaacgaa cctcttcggc ttttagatat tggagctgga gctggatttc ctagcctacc
    18961 tatgaagatc atctttccgc aactagatgt taccatcatt gattctctta ataaacgaat
    19021 taacttttta catttgcttg ccgaagaact agagcttgaa ggtgttcatt tctatcatgg
    19081 tcgtgcagaa gactttgcac aagataagaa cttccgtgca caatttgacc ttgtcacagc
    19141 acgcgcagtt gcccgcatgc agattctttc tgaattgact attccttatt tgaagctcca
    19201 cggaaaatta atcgcactta aggcgtccag cgcagaagat gaattgaccc aagcaaaaaa
    19261 cgcactcaat ctcctcttcg caaaagtcat cgaaaaccac gactatactc ttccaaatgg
    19321 cgaccctcga acattgacca tcgtcgaaaa gaaaaaggaa actccaaata agtttccacg
    19381 caaagctggt atgccaaata aaagacccct ttaaacataa gaagagcgag tttcactaag
    19441 aaacccgctc ttttattatc caatttttgt aatattggtt gcttgaagac cacgttggcc
    19501 ttgctccact tcaaatgtca ctttttgacc atcttccaac gatttgaaac cattagactg
    19561 aatttcagaa aagtgtgcaa atacatctgg accgttttct tgagcaataa aaccaaatcc
    19621 cttttctgca ttaaaccatt taactgtacc ttgtaccatt tgtgttacct ctttttattt
    19681 atttgtaaaa cttatcaaga ggaaaaacaa aagatgaaac tgatacttaa actctaaatt
    19741 tatttacatt ccctactgta acagtatatt tcctatatgt caacgataaa gggttgataa
    19801 gtccaataaa ctcaataatc atcgccacgg attatagaat cgcccctgat taacaaaaaa
    19861 tagatagatt gtcaccacta ctagagcaag aataaatagc aagacagcgt aatctattct
    19921 ctgtagaggc tgttgggtat accatgttct ttttttattt tttccaaaac gtcgcaattc
    19981 catagccgtt gaaatcgtat caatcctctc caaggagctg aaaatcagag gaatgacaag
    20041 ggatagattc ccttttatac gatccatcaa ttttcctttc ttagacaatt ccaaaccacg
    20101 cgcttcttga gacattcgaa tcgtataaaa ctcttcttga atatctggaa tataacgcat
    20161 ggtcaaactg acggcgtaag caactttgta ggatacccca atttgattca agctggaagc
    20221 aaactggcta ggatgagtgg tcatgagaaa gataatcgct aaaggaactg tacaaaaata
    20281 cttcaagaga agattcacca gataaaatgc ttgctgactc gtcaaggaat aaactcccag
    20341 acctgatagc aagggagtgt ctgctccgta aagttccact ccataccgtg gtgcaaacaa
    20401 gtgaaccatc agggcattca ttgcagcaaa aatgattgtc agaattaaaa caagagagat
    20461 ttctttataa cgaatccctg acattttaaa caaggctaga gaaaatactg cgataaaaag
    20521 aatcaagcgg gtatcgtaag taatcatagc aagaatggaa actatgagaa aaaagagtaa
    20581 tttactgaca gccgataaac tatgaatcaa gccagttcct ggatggtaac caattagttt
    20641 ttgttgactc atcttcctct cctttcttcc tgcatataaa acgtcgttaa ttctaaggga
    20701 ttaactccca ccctctccgc caagtgaaaa attgatgttt cttttaaatt ggctcgctca
    20761 atcaccgtat catcagataa aatttctgct ggactggcat cttcaataat ctgcccatcc
    20821 accacaacaa cagctctatc tgaataatct agcatgagtt gcatgtcatg ggtaatcatg
    20881 acaatggtgt gcccttgagc atttaattga tccaaaaact ccatcatttc ccgataatgt
    20941 cgttgatctt gtcctgctgt tggctcatct agcaaaataa tttctggatt gagaaccaag
    21001 atagatgcta tcgttacccg ttttttctgc ccataggaaa gtgccgaaat cggccaatta
    21061 cgaaacggat acaggccaca tactttcaag atatggtgaa ctcggtgttc aatttcttct
    21121 tctgtcaccc ctcgcatgcg caaaccaaga gcaacctcat caaagatcat cgtttggcta
    21181 atcatttggt tgggattctg aagaacataa ccaatccgtt ctgctcgctc tttgacagaa
    21241 tcttctttga ttgactgccc cttccagaga atctcaccct caccctgaat aaaaccacaa
    21301 agcacctttg ctaaagtaga tttcccagca ccattttttc caacaatagc tagacgttcc
    21361 cccttatgaa tcgtcagttg aatgtctgta agaacttgtt tgttaggata ggaaaaataa
    21421 agatgcttga cttctaacaa agcctctttc tctccatttt caaagtgtag agtcggtagg
    21481 gatgctatat tcaaagcctc aatatcaatt tcccaaactg aagagaggcg ttctgcctgc
    21541 gcaatcggat atcctaaggc gcgaagagtc gatagatata agggttcacg gatgccgttt
    21601 tcctgtaaca atgaggtacg taataaatca tccggtcctc cattgaacaa aatccgacca
    21661 tcattaatca atacaactcg gtccacctga cgatacagta cgtcctctaa acggtgttcg
    21721 ataataatgg ttgtggtccc ttcttgcttg tgcagacggt caatcaaatc aatcgtatct
    21781 tggcccgatt tggggtctaa attagcaagt ggctcatcaa acaacaaaat aggactctca
    21841 tcaataagaa ctccgcccag actgacacgt tgcttttgac ctccagataa atcttgtggt
    21901 cgatgtgcca gcaaatcggt caaagacagt ctttctgccc aatctcctac tttttgcttc
    21961 atcaccacct ggctttccat gtcgttttcc aaagcaaaag ctaggtcctc ggcaactgat
    22021 aagccaatga attgaccatc tgtatcttgg agaaccgttg atacgagcaa ggacttatca
    22081 taaactgaaa gattaaatgc ttcctgacca tccaatagta aacttccgct atgttctccc
    22141 ttgtaaatat tgggaataat accattaaga cattgtccaa tcgtcgactt tcctgaacca
    22201 gatgggccaa taatcagaac tttctctccc tgataaatcg ttaactgaat atcttttaaa
    22261 gtgggttcct gttgcgcttg gtatttaaat gtaaaatctt taaactcaat gatttttttc
    22321 ataggactat tatagcgtaa attgactctg aaaaaaagga agaatcatca gtttctccct
    22381 tttcaaataa gttcatctat gattctagag cagatgaatt ctaacttcct acatcacaat
    22441 cacattaaaa tgataccatc aaggtccgta aaacttgctc cataaaagcc acgggcatct
    22501 gtcgggcatc ctgtaatttg cccgccattt gcttcaacac gctcgataat tctatctact
    22561 tcttccctac tcgccacatt aagcgaaatc aagacttcat tgccactcgc tactacctga
    22621 aatggtacgc gttgagcaaa gctatctgcc tgcatcaaaa tcaagttgcc acccttaggc
    22681 aaagtcgcag acttaatatc tccaaacgtc gcaactgcaa aaccgattgc ttcataaaac
    22741 cgaccagcta ttcaaggtct gctactgcta atactcaatg aaaatcaaaa gtgaccgagg
    22801 aaacgaagcc gaagatagaa ctgaagttca tcaaggcaag ttgacaacgg ataatgttga
    22861 ttttcgaagg ggataagttc atccaaaatg acttcatctc cttctctttt ctaattgata
    22921 ggcttcgtat agaatggact gaaaaaatat aaagaattct gattgcacaa aaaaattgca
    22981 ctgatttttc aatgcaattt tggtattact aagcatttgc tggagtaaga gtttccccaa
    23041 tcgcttccaa gcgttctgcc cattcttgac gagtcaagcc gttttcagag atgtaacggt
    23101 tgcgctcatg agcacggcat tcagctgaac agccacgaac atacttgtgc tcattctctt
    23161 ctgatgtcaa aatacgacgg ttacagaatg gattgccaca gttgacatag cgctcacatg
    23221 gtgtgccatc gaaccagtcc ttaccaacga caactgggtt aacatggtta acatcgaccg
    23281 cgatacgctc gtcaaagaca tacatcttcc catcccacaa ttcaccacga acttctgggt
    23341 ctttaccata ggttgcgata ccaccgtgga gctgaccgac atccttgtag ccttcacgaa
    23401 ccatccagcc tgagaatttt tcacagcgaa caccaccagt acaataaaca actacgcgct
    23461 tgtccatgaa tttctctttg ttatcacgga cccattgtgg caactcacgg aagttgcgga
    23521 tgtctggacg gatcgcacca cggaagtgac caaggtcata ctcatagtca ttgcgtgtat
    23581 ccaaaacaac tgtatcttcg tccaagagag cttctttgaa ctcttttggt gataggtagg
    23641 cacctgttgt cacgagtggg tcaatatcgt tgtcaaagtc gttgtcttct aaaccaaggt
    23701 gaacaatttc ttttttataa cgaacaaaca ttttcttgaa agcttgctca ttttcttcat
    23761 caatcttaaa ccacaaatcg ctgaacaatg ggtttgcatg aacgtagtcc atgtactttt
    23821 gagttgtttc atagtcacca gaaacagtac cgttgattcc ctcatcagca atcaaaatac
    23881 gtccttttag tccgatagac ttacagaaag ctagatgctc agcagcatat tctttggcat
    23941 tttcaattgg aacatacttg taatagagta gaacgcgaat atcttttgac atagtgtctc
    24001 cttttcaatc tttgcaatag atgataaaac tctgtcattt ctaataaatg ataccttacg
    24061 tattatatcg tttagcccct caaaagacaa aaatctgaac tgaaaattta gaacctgtat
    24121 tcgcaggttc agtgcttata tgtaaaaaaa tacggtaaca tgaatgacat gctactgcat
    24181 ttattgaagg ttcgctataa cttcttagtc gtctaattct gttttcagtt gtcggagttt
    24241 ttccaaggta tcatgtccga taagttggtc catttttcgc ttatggcgtc tagcaatatt
    24301 ttccttccat ttatcttcaa taggattatg tggcttctcg gctttccttt gctctttgat
    24361 ttctcttgcc tcctgccact ccactccttt aataacttct tcccaatagc tggcaatggc
    24421 agagcagaga tagagttgga ccttattcaa ccagtgtcca aaaaaagttt gcggagcact
    24481 ttcctccact agccgatagg tcctttggat ttcaataagt tgactttggt atttttccca
    24541 ctggagcata gctttactcg gcttttttcg ataaagttga cgctgtttga ttagagctat
    24601 atacggtgca acaaaacgac tcgtccgtat cttgataaaa tttctggagg agcgaatggc
    24661 caccagcatg cctgagccca ataagcgttc aacctccctt gcctgattat ctggaaaacg
    24721 gtaatgaact tgccacccct cttcttcaac cactaagcga atctgcatcc taccattttg
    24781 ccaactcgcc tccacctctt gcttttcatc ccataacttt tgaaaaaaga gaagaaggta
    24841 atagccttgt ttactaagtt cataccaact gttcgtgtga taaaggtagg tccgaatcgc
    24901 tcctttcata taaaattcgc catggaaatc ataaaaagtc ggctgtttat atgtagattg
    24961 tgatgggtgg ttactaactc gaaaaacctt ataataataa ttattccaaa gaatacatcc
    25021 ataaattgat ttcgtcgttt tcgattgata aagacttaaa acttcctcgt caggattgag
    25081 tatagaatga ataatcggtc ccaacttttc ttctgtccag accatacttc tccccttgaa
    25141 cacatgtttt tgtttgtttt atattattat atcatatatg tattttttgg tattgaaaaa
    25201 accctagaat tttttctagg gaaaataaaa acttaatctt tagacaaact acctgtcttc
    25261 gtttgagatt ttgcataaac aaccaaaagg agtgtccctg caatagcaat tgtaatactg
    25321 tttgcaatac ctgctacaag tccctgtgca aagaccttat tcgccgcctc actatagata
    25381 agaatatcta aaactggggc aatgactccc caagcaagca cattcgccgc aatctgaaca
    25441 aggttaaaga aaagaatatc cttcccttca aaaatccctt cttgaatacg cagacgtttt
    25501 ttggtaagac caacaaccaa accaaagacc cctgatgcca aaatccatga ccaccatgga
    25561 ccgtaagtca acgaatcctt aagcgtgtgc ccaatgaaac cgaccaagaa gccaaccaca
    25621 ggaccaaata caactgccaa tagcgattga acagcgtatt gaagctggat agaagtattt
    25681 gggacaaagg ttggaatatt gattaaatga ccaataacca caaagagggc tgcgccgata
    25741 ccagtagcaa cgactgtttt gattgaatta tttttcataa ctatctccta aaatttcttt
    25801 aattactaat acgtttgatt tcaatatgcc agttttgacc tacaccgaca ttataagcct
    25861 tggcaaatga gccctgatta atcgcaacac ctacacgata gagggaattg atataaatca
    25921 atggctgtcc gatacgtaca tccgcaaagg acttgccata ggttacttgg ttttgataca
    25981 caagcatgtc gttattgtat atggtcactt caaagcgatc ttcaaactgc ggttgcaagg
    26041 tgtaaaattc ttccctcgta atcgaggtcc aaagcgagcc aaatcgaaca tccagaatat
    26101 caattgcacc ttttacatag tccgaaccaa cttccgttgg gactgttgga atttccacaa
    26161 tcttatccac gcttaattct ggaccaactt cttcaaagct aatgtgtcca gaagccaatt
    26221 tagctcccgt ataggcataa acatctcgac catggaaggt gtacgaatgt tctgtattgg
    26281 cacggcgatt ggccacctct gaaatttctc gaaccgcctt tatccccaca tattttttga
    26341 tgaaggatag cgtcccatta tctggcgtta caatgtagtg attttgttcg gtcaaagcta
    26401 ctacactctt acgttttgaa ccaactcccg gatcgacaac cgaaacaaat gttgttccct
    26461 ccggccagta ttcgaccgtt tgaaagaggc gatatgaacc ctcaaagata ttgtacggag
    26521 taatatcatg agttagatgg tgaacaacta aatctctcga ttcttggaga gcaacaccaa
    26581 tcatcgctga aactgcacca tcaactaaac caaaatctga ttgtaaaaca agtaaattat
    26641 ttgacataca ttctcctaat cttattaccg ttctatgata acagaaaacc cgtgaccatt
    26701 caaatagata tttccaaagc ctggctatag tttttcctta tacctcatct atcaagcact
    26761 ctactatcag ccaccgaaaa ctccgcaaat ttttccatcg taccttattc aaacttaagc
    26821 taaaatatcc ccacttctct agttccaacc aactatcgtc tttgagcaat tggatacaaa
    26881 gaaaactgcc taacggcagt tccaatctcc aaccttctag gacgtcccac gtacaatgag
    26941 aatcgtctac cgacgattcc aatctccaac cttttaatat aaaaaaagtg ctactagcac
    27001 tttttttata ttaaaaccca tctacatttg tgtagatttt ttggacgtct tcgtcgtctt
    27061 ctagggcatc gtagagtttt tcaaatgttg cgaggtcatc gccttcaagt gatacttctg
    27121 attgtgggat catttcaagt tcagtgacgt tgaactcttg gattcctgat tctttaagtg
    27181 ccacgattgc cttgtgcaaa tcagttggag ctgtatagac agtgattgtg ccgtcttctg
    27241 cttctacgtc atccacttcg acatctgctt caaggagcaa ttcgaagatc gcatctgcat
    27301 catcaccagc aaagacaacc acaccttttt tatcaaacat gaatgataca gaaccagatg
    27361 cacccatgtt accgccgttt ttaccaaaag cagaacgcac gttagctgcc gtacggttta
    27421 cgtttgatgt caaagtatca acgataatca tagaaccatt tggtccaaag ccttcgtaac
    27481 gaccttccac gaaggtttcg tctgtgtttc cttttgcctt gtcaatggcc ttgtcaatga
    27541 tgtgttttgg aacctgcgct tgcttagcac ggtcgataac aaatttcagc gctgagtttg
    27601 tttctggatc tgggtcaccc tttttcgctg ctacatagat ttcaacacca aatttggcgt
    27661 aaacttttga gttagcaccg tcttttgcgg ttttcttggc tacaatattg gcccatttac
    27721 gtcccatggg gaacctccta cattttataa aatcgcttta ttataccata aatggcaagg
    27781 attgagaaga tttttaaaat cttcttcact atacag
//
LOCUS       DBNFCO010000021        27567 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.021, whole genome shotgun sequence.
ACCESSION   DBNFCO010000021 DBNFCO010000000
VERSION     DBNFCO010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 27567)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27567)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27567
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.021"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            47..958
                     /gene="murQ"
                     /locus_tag="AC1PIV_000756"
     CDS             47..958
                     /gene="murQ"
                     /locus_tag="AC1PIV_000756"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016835 - carbon-oxygen lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009254 - peptidoglycan turnover [Evidence
                     IEA];
                     GO_process: GO:0046348 - amino sugar catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HIP6611793.1"
                     /translation="MDIERLNTEQSNPDSFAIETMSIGEITAYINREDGLVALAVQRI
                     LPQINAVIEIVVDCLKKDGRLIYVGAGTSGRLGVLDASECPPTFGVSPELVQGLIAGG
                     NGAVRAAKEGAEDNRAAAVEDLQQIGISAKDVVIGLAASGRTPYVLEAVTYAREIGAK
                     TASISCVQDAEISPLVDAPIEVLVGPEVVTGSSRMKAGTAQKMILNMISTTSMIQLGK
                     VFRGFMVDVQPTNQKLIQRAKRIICETTGCTEMEAEHIFQQANQDVKLAILMQLSQLD
                     QIEAKKLLENYHNHISFAIQSILDKEN"
     gene            960..2387
                     /locus_tag="AC1PIV_000757"
     CDS             960..2387
                     /locus_tag="AC1PIV_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HIP6611794.1"
                     /translation="MKNTKDVAKQVLENVGGRENILGNAVCMTRLRLQLRDDKLVHLD
                     SLKNIEGVLGVVEADTLQIVFGPGTVTKVGQAFSELTGISLGSVEEDYTTADVAATNK
                     RINKEKYDKPVQRFLQKIANIFIPILPGIIAAGLINGITNVINVSTGNAFAMEWWYQC
                     IRTMSWGLFTFLPIYVGMNAAKEFKGSPILGAMAGAMSVAVPSMPLLTVVDDKSILLP
                     FVDKAFSPSAGGLLAALFVGIFFAFLERNIRKYMPSFLDTFLTPLCTVILGGLVALLV
                     IQPLGEVLTTAIYSGLNFVYEKLGIVGGYILSAGFLPLVSVGLHQALTPIHVLLNDPS
                     GPTGGINYLLPILMMAGGGQVGAGLALFLKTKNKKLKQLTRDSIPVGILGIGEPMMYA
                     VTLPLGKPFLTACLGSGFGGILAVLFHLGTVSQGVSGLFGLLIMVPGSQLQFVIAMLA
                     AYVGGFVLTWFFGVDEDRIETVYGS"
     gene            2377..3195
                     /locus_tag="AC1PIV_000758"
     CDS             2377..3195
                     /locus_tag="AC1PIV_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MupG family TIM beta-alpha barrel fold protein"
                     /protein_id="HIP6611795.1"
                     /translation="MEVNDFFSRFGFSLYLSNSFANSEKWFIEYQNAGFSFVFSSLNI
                     NEEEKGDEKIRHIVTKCQREGLTLIVDINQDSLKRYGNEGIKKLGIKALRIDDGITIE
                     VMKSLSEDFLLVLNASTLSDDFLRKMMDVGIEKTKVLACHNYYPKPYTGLGGSSVRDL
                     NSRLHSCGIKVITFIPGDNKRFPLFEGLPTVEEHRALPPIQAALDCLMCCESDYVCIG
                     DNALSSASLERFSYLTKGIIALSAQFPKQLKGMNFENRIDAVNMSYVLAIQGLS"
     gene            3207..3407
                     /locus_tag="AC1PIV_000759"
     CDS             3207..3407
                     /locus_tag="AC1PIV_000759"
                     /inference="COORDINATES: protein motif:HMM:NF017701.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar glycosidase domain-containing
                     protein"
                     /protein_id="HIP6611796.1"
                     /translation="MQGPASHRKRGDIVLANEQFLRYQSELEICLVDLPQDDRQMVVG
                     HVHESDVPLLDFVKHPFHFTFI"
     gene            complement(3490..4017)
                     /locus_tag="AC1PIV_000760"
     CDS             complement(3490..4017)
                     /locus_tag="AC1PIV_000760"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIP6611797.1"
                     /translation="METCHLVVPSLKWKNQILAYKEAFSNEHLHGGGKLQQFEAVEEW
                     LEHIKAVSSYGTNHTERSPSSTFLCIREKDQQMVGICTIRHDLNHEHLKNYIGHIGYS
                     IHPEERRKGYATEQLRIALLEAKKLGIAQVLITAADWNIASQKTILANGGVYEDTRID
                     PNSSERMLRYWIENL"
     gene            4219..6438
                     /gene="pnp"
                     /locus_tag="AC1PIV_000761"
     CDS             4219..6438
                     /gene="pnp"
                     /locus_tag="AC1PIV_000761"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HIP6611798.1"
                     /translation="MSKQVFETVFAGKKLVVETGQVAKQANGAVVVRYGDSTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGWMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDPDASAPMAAMFGSSLALAISDIPFNGPIAGVQVGYVNGELI
                     INPDQAQQEASLLELTVAGNKDAINMVESGAKELSEEVMLEALLKGHAAIQELLDFQN
                     QIVAAVGKEKADVELLQVDPELQAEIVAAYNDDLKKAVQVEEKLAREDATNAVRETVI
                     ATYEEKYAEHEEFDRIMRDVHEILELMEHTEVRRLITEDKVRPDGRRVDEIRPLDAEV
                     DFLPNVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDDEYKKRFLHHYNFPQYSVGS
                     TGRYGAPGRREIGHGALGERALEQVLPSLEDFPYAIRLVAEVLESNGSSSQASITAGT
                     LALMAGGVPIKAPVAGIAMGLISDGTNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIDGITPQILEEALAQAKKARFEILDVIEATIPEVRPDLAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEDGLVAIFSPDRAAIERTKEIIAGLVREAKV
                     DEVFQAKVVRLEKFGAFVNLFDKTDALVHVSEMAWTRVNKPEDLVEVGDVVDVKVIKI
                     DDKGRIDASMKALLPKPEGYVEPEKRERSEKPRRHKEHKEKKDNNFGEFKFHKVDKK"
     gene            6494..7111
                     /gene="cysE"
                     /locus_tag="AC1PIV_000762"
     CDS             6494..7111
                     /gene="cysE"
                     /locus_tag="AC1PIV_000762"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HIP6611799.1"
                     /translation="MGWWKDTIEIVKEKDPAARNSLEVLLTYPGVKALAAHRLSHWMW
                     QNGFKLLARMHSQFWRFWTNIEIHPGAEIASGVFIDHGAGLVIGETAIVESGVMLYHG
                     VTLGGTGKDTGKRHPTVRKGALVSAHAQVIGPVEIGENAKVGAAAVVLADVPADVTVV
                     GMPAKIVRVHGQKDEKIIHDMEDGREHYTTKLAELREASHRSSHL"
     gene            7126..7899
                     /locus_tag="AC1PIV_000763"
     CDS             7126..7899
                     /locus_tag="AC1PIV_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HIP6611800.1"
                     /translation="MLLEEFENTSAVIEPTDKAIRGGGEVCETMIFSFNGEIVDRVSQ
                     LAESREGGHLQTLNGRHPWYILERDGLQVAVMLAVIGAPMAVGHLEELKACGFENFIV
                     LGSCGVLDKSLAADKIILPSSALRDEGTGYHYAPASEEISYDPALLLTMEKALDQAGI
                     EHVRAKTWTTDAFFRETAAKVKRRLAAGAMVVDMEASAIMAWANFRQAKVYQFFYTAD
                     YVDHHKNEWDARREERMADSMTFFEVAMAIARKLESRSC"
     gene            8089..9432
                     /gene="cysS"
                     /locus_tag="AC1PIV_000764"
     CDS             8089..9432
                     /gene="cysS"
                     /locus_tag="AC1PIV_000764"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000591125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HIP6611801.1"
                     /translation="MIKIYDTMTRSLRDFVPLEEGKVKMYVCGPTVYNYIHIGNARSV
                     VAFDTIRRYFEYRGYDVTYISNFTDVDDKIIKAANEAGMTTKELSDKFIAAFKEDVTK
                     LGVKPATKNPRVIDYMDEIIDFVQVLIDKGYAYEAAGDVYFRVEKVENYARLANKTLS
                     DLEVGASGRVEGEGQLKEHPFDFALWKTAKSGEVSWGSPWGAGRPGWHIECSVMATEI
                     LGATIDIHGGGADLEFPHHTNEIAQSECKTGQTFANYWMHNAMLNINDEKMSKSLGNF
                     LTAHDMLEQIDGQVLRFFLATQHYRRPLNYTEKAISDAEINLKYLKNTYTQPVQNSVD
                     KSALELHLAAFEAAMDDDFNAANGITAIFDFAKWINSGNYDETVKEAFGKMLAVFGIV
                     FEEEVLDSEIEALIAERQAARANRDFATADRIRDELAAQGIKLLDTKDGVRWTRD"
     gene            9425..9823
                     /locus_tag="AC1PIV_000765"
     CDS             9425..9823
                     /locus_tag="AC1PIV_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HIP6611802.1"
                     /translation="MTKAVDVNLINGIALAFEGDAVYSMYIRRHLIFKGLTKPNKLHG
                     EANKYVSAKAQAGLISALLEAQLLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGF
                     EAVLGYLHMTEQMERLDELVGWCIKFVENN"
     gene            10069..14544
                     /locus_tag="AC1PIV_000766"
     CDS             10069..14544
                     /locus_tag="AC1PIV_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033925 - mannosyl-glycoprotein
                     endo-beta-N-acetylglucosaminidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HIP6611803.1"
                     /translation="MTKCDFDKRQRFGIRKFTIGACSVLIGATLFGTQVSADQLENVD
                     SLSEPAVELSSVVNEHVEKTEAEEGMSPISADEKAVTEELNGEASVSDSREEKLPSAP
                     SDNPENKLEDTEEAEDKEVDSSDSGLLLSDFPQVEDQGIRPKEIKFDNWDQVLAWEPG
                     ARPDDDLNRASVELVERFRGHVVNERANENAKVEALSNTNSKAKDHASVGGEEFKAYA
                     FDYWQYIDSMVFWEGLIPSPDVIDAGHRNGVPVLGTIFYNWSSSIEDQEKFVSSMRQD
                     PDGSFPVARKLVDMAKYYGFDGYFINQETTGGLVQPLGETMRNFMLYTKEYAESIGYP
                     ITYSWYDAMTYEYGRYHEDGLGEYNYPFMEKEGDKVPADHFFANFNWTRAKNNYSIEV
                     AKRIGRNPFDIFAGFELQRGGSYKTQINWDALFDENGKLKLSLGLFAPDTITSLGATG
                     EDYHENENIFFTGYQGDPTKQKPSDKNWYGLANLIADKTAITSSNFNSSFNTGHGKKW
                     FVDGKVAKDGEWNYRSVSGILPTWRWWIEASGEKLAAAYDFDDAYNGGNSLRFTGDLE
                     KDGKQEIKLYSTKIPLSETSRLRVAHKGGQGANISLALALEPDYQFANKEAWRLLKLS
                     GDWQDQTFDLSSLAGKTVYGIQVVVENEAALSDFDFRLGQLAIYDQENSPTAPKDGQV
                     LAKRLKNAQDAEAVISFTGTDDADYYEVYAQVDGQWKLLTGSSNTRIYLPQLVRSAQA
                     EGRTQALKVHAVGKNGLRSEAGEFIFDWEMTVKDTSLPKPSAENIVLGAEVIGSSFAK
                     KEGGEGIEGMLNGTITSLSDKWSSHQLSGHVDIRLTQPRTVVRWAMDHAGAGGESVND
                     GLMNTKDFDLYYKNENGDWVLAKEVRGNRDHVTDIVLDKPIRAQEWRLDVLTSDNGTP
                     WKAIRIYNWRMYEELDMETPNIPMTHAVARHLGNHQIQVGFKDVPANRKIALYSSPDA
                     VKPLAELETTESGNLIFDPIRFESLPEFIYYRTLEEGKDWSNLLAIRVPQGEKVVKAM
                     EWIAPLEKKVYRQGSPLSLAGAQFRVVFEGDWPAERVNTTNPAVTVRGFDPQKLGEQT
                     LTVSYLGETLAQPLMVYVVEDIAQGEKKAVGLEIQQLPKVQYVVGDDLDVTNGRFAII
                     YDDESTQSFSLTEAGVEIVGFDSRKEGRQSLGLRYAGLETSFDVLVSPKPIVNDEYLK
                     QKIAEIEALQTQTAYLYSSEQTQLALQTALEEAKSVVADTNRTVEQVEAAQTLLEKQL
                     GELDGEKLYQADLGRLNQLIQEVKGIDRPINSSELSSLLEKTEKILGSDSIRPDEMKE
                     LLSEWTDLFEQSSLVTHVGTRDSMESKNLLAPEKPRMDLTYELVPRQIITQTSTDLPL
                     GKERIVQEGADGQMMIAHLVYSDGRRELYSRIVADESQPKIVEVGSGLPIQQEKTLMV
                     ENSLQVEKQIRDASLQKSGLPQTGDTYQEKYVFLGLIGVALAGLSQLAKLRKQGE"
     gene            complement(14596..16725)
                     /locus_tag="AC1PIV_000767"
     CDS             complement(14596..16725)
                     /locus_tag="AC1PIV_000767"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HIP6611804.1"
                     /translation="MYTSIVSTIDTRYGTYNSHAFSNGNTLPLIGVPFGMNYFAPQTS
                     DQTGNWWFNPYEPVYQGIRLTHQPSPWLGDFASLLLTPVTGELSRDSLFHRQSSYQLD
                     QAIFRPDLLQLQSNRYRLISRLAPSRYGASFEIASFANQPIGMVFYSSGKSIYRLLNP
                     HQLLIQIFQVSACQSPDFCMYALLEFEEEITECYHLVKDRKIAKTEVVGEDLHLRINF
                     SSTSIKGRLATSFISPEQAAFLLKDVPDFLQAQKQAENTWNQLLGRIQIRDKKTEDIN
                     FFYHCLYRCLLYPQTFYEPNPDGQAIHFDPISNQAKLGKFFTNNGYWDTFRSSYPLLS
                     LIYPDYLEEFLHGILQHYRDTGFLPKWLSPDERGIMPGTLVDGVIADAACKGLVPDLM
                     EDFLQAMIETSQKTDADQRYGRHGSQIYRQLGYLPLDFNESVSHSLDYAYSDWAISQV
                     AEKLRQDQLAKQYAQMCLGYRQLFDSQTGLMRAKDRQKQFRADFSPLSWGRDYAECSA
                     LQATLSVFHDIDGLIELMGGKEAFTNYLIQLCNQEPYFSPEQYGYEIHEMSEMAQVNL
                     GQLAISNQPSFHIPYLFQWSTKPEYTSLLIHKIRQTAFKTGFQAYPGDEDNGSLSAWY
                     IFSCLGFYPVCPGKADYQIGLPHFKEVDLLLADQHKLTISTPKSDANFQFVKQVSLDK
                     QVVQTIKHDQLIKSNCLEFDLSILPSN"
     gene            16972..18258
                     /locus_tag="AC1PIV_000768"
     CDS             16972..18258
                     /locus_tag="AC1PIV_000768"
                     /EC_number="3.2.1.163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004559 - alpha-mannosidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HIP6611805.1"
                     /translation="MFYTKEIIENWLTGIQKKTADHPSWGSVFERCYTDTLDRTISQL
                     EDGTTFVLTGDIPAMWLRDSTAQVKPYLALARKDEKLRQMIVGLVERQMAFILMDPYA
                     NAFNQAANGRGHQTDHTQIGPWIWERKYEVDSLCYPLQLAYLLWKATGETSHFNQTFF
                     GAAEKIVQLWKLEQHHENSPYSFERDTDRLEDTLTHQGKGAPCAYTGMTWSGFRPSDD
                     ACIYPYLIPSNMFAVVVLGYLGEIAEQFASEEFSDLAEGARRLAQEIDQGIRTFGLTK
                     NQAGETIFAYEVDGLGNQSIMDDPNVPSLLAAPYLGYCQKDDPIYLATRRTILSQENP
                     YYYEGDYAAGLGSSHTFYRYIWPIALAIQGLTTDDKEEKARLLDTMVACDGGTGLMHE
                     SFHVDDPTLYSREWFSWANMMFCELVLDYYDIRPEE"
     gene            18260..20932
                     /locus_tag="AC1PIV_000769"
     CDS             18260..20932
                     /locus_tag="AC1PIV_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HIP6611806.1"
                     /translation="MGKETVHIISHSHWDREWYLPLEEHRMRLVELFDDLFDLFETDP
                     EFRSFHLDGQTIVLDDYLEIRPQNRELLKKYIQDGRLIIGPFYILQDDYLITSEANMR
                     NTLLGHLESKKWGRAPKIGYYPDTFGNMGQAPQLLRQAGIDVALFGRGVKPVGFDNQV
                     LGDDQFQSTFSEMIWEGADGSQVLGILFANWYSNGNEIPVDEEEARVFWEKKLADVRK
                     YASTSHYLLMNGCDHQPVQKNLSQALRLARKLYPDIDFVHSSFEEYIAAVKEELPVDL
                     SRVKGELISQETDGWYTLANTASSRIYLKQANDQASQLLEQVVEPLVVMTGDKVPRDE
                     LRYAWKLLLQNAPHDSICGCSVDQVHSEMETRFKKVKQVAHFLSQRSLDRWEKQVDSS
                     QLDGLLFTVFNTTACRQTQLVEVDLLVEQEDFRDGQLEQHFQSMAAISLPALGLFTSQ
                     GQEVEATIEDLGVNFRYDLPKDAFRSANFARQIRVRFVVENQAPFSWQTYQVKPIGDT
                     RVNSSLSEQFENDYYRINVMDGQLLLEDKRTGQAYKDWLRFEDCGDLGNEYIFMAPKN
                     DQPIYGQIEYFGLVYQTEAVSIAKVMHRLQLPVAMETSLEDEQKRLVEFKHRTSQRSQ
                     EKKDLLLTTYLTLYRHQSQIRIQTDFHNQIKDHRLRAVFDIGIEAENHLADSIFEVVE
                     RPNQPHPAWENPSNPQRHRSFISLSDGRQAMTVSSKGLHEYEILDKGKIALTLLRATG
                     ELGDWGYFPTPEAQCLRECQLDYAFEICPVEEGFASFQRAQAFQGHLLTKQLTSHSGH
                     LPCDHQFLSHPALEEDRLCVTSLKVAETSDRILLRYYNMSQEQLAGWSEWTEGVDLLE
                     EPLEDLPARIGSQAIRTEVVGHHGKEKEHGSSLF"
     gene            20913..21779
                     /locus_tag="AC1PIV_000770"
     CDS             20913..21779
                     /locus_tag="AC1PIV_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HIP6611807.1"
                     /translation="MVVACFDIGGTGIKAALIGSDKQINYRQEWKTPSSLAELLALMD
                     SVIQPVDGLEAISLSIPGAVDLETGVIQGLSAVPYIHGVSWYELLSQYGCPVYLENDA
                     NCVGLSELAVDDQLSTFACVVCGTGIGGALIVDRKLIRGKQGFGGEFGYMLIATGKGP
                     LKNWSQLASTGSLVRQVASQYEEAVEDWNGKRIFELAEQGDEVCQLAIEEMTRNLAYG
                     ILNISYFLEPEVLAIGGSISQNPVFIQAIQEQLEAIQKEYPEEFPYLPAIRACHYQQD
                     ANLMGAYMKTLQ"
     gene            21789..23672
                     /locus_tag="AC1PIV_000771"
     CDS             21789..23672
                     /locus_tag="AC1PIV_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HIP6611808.1"
                     /translation="MMLQINHSLRQSEGVLEEICSSLGLDCQLELEVGGKESLRIEGS
                     AGSYRIRAPKEHMIYRGLLVLASQLAQGETDIQILERPAYRQLGFMEDCSRNAVLTVE
                     ASKILIRQLALIGYSHFQLYMEDTYQLRDEPYFGYFRGAYTKEELQAIEEECHRYGME
                     FIPCIQTLAHLIAYLKWNISSIQAIRDVDNILLIGDERTYALIDKMFEALSHLKTRTI
                     NIGMDEAHLVGLGQYLNQHGYQKRSLIMCQHLERVLDIADKYGFHCSMWSDMFFQLLT
                     ASKDYTGQLEIDSEIQAYLDRLKDRVTLIYWDYYQTSRESYGQKLASHQQLGDQIAFA
                     SGAWKWIGFTPDNDFSMRIAPKAHAACQEYGVQEVTVTAWGDNGGECATFSILPSLHA
                     WAELQYRGNLGCLAEHFYQLHQVSLDDFLQLDLPNKTPSHPGPGHHGFNPSRYILYQD
                     ILCPLLQEHIDAEKDNAFYQELAPRLAEIGSRAKGYAYLFDTQAKLCQVLATKAAISV
                     GIRQAYQEGNRQVLAEKVDGLQQLRIDLESFYQALSYQWMVEKKVFGLDTVDIRLGGL
                     DTRIRRAIQRLQAYLNNEVPKLDELEVPILPYDDFHQDKGFIATTANQWQIIATASTI
                     YTT"
     gene            23874..24803
                     /locus_tag="AC1PIV_000772"
     CDS             23874..24803
                     /locus_tag="AC1PIV_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIP6611809.1"
                     /translation="MKDLIKNLKQNAIFFLMVLPGVIWLILFFYIPVFGNVIAFKDYR
                     HTGNGFWDSLIQSKWIGLDNFKFLFQSSDAYIITRNTILYNLGFIVLGLIFAVGIAII
                     FSEMRSKKLVKIYQTTTLFPYFLSWVIISFFVYAFLSPDKGLINNILKGMGMDPINWY
                     STPTYWPFILLFLGIWKGLGYNSIIYYATIMGIDPTYYEAAIVDGATKWQRIRYVTLP
                     QLMPLMTILTILAVGNIFRADFGLFYQIPKNSGPLFNVTQVLDTYVYRGIAGTGDIGM
                     AIAAGLYQSVVGCILVVVTNLIVRRFDKESALF"
     gene            24813..25736
                     /locus_tag="AC1PIV_000773"
     CDS             24813..25736
                     /locus_tag="AC1PIV_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HIP6611810.1"
                     /translation="MKKKKQITSVSIHSFSKKTDLFFSSLLGIFALSCTLPFIFVIII
                     SMTDETSLAINGYSFWPEQWSLAGYEYLFQLKDQILQALFITFFVTIVGTSLNVFFTV
                     LYAYAISRNSFRYRRFFTLMALFTMLFSAGTIPTYIVMTSFLNLKDTVAALILPMLLS
                     PFNIMVMRSFFRKTISESIIESARIDGASEFRIFFQICLPLTLPGIATIALFTALAFW
                     NDWYNALLYIQSDNLFPLQYLLMKIQANIQYLSENAAAAAAMSSEVAGALPKEATRMA
                     IVVVSTLPIACLYPFFQRYFVKGLTIGGVKE"
     gene            25806..27287
                     /locus_tag="AC1PIV_000774"
     CDS             25806..27287
                     /locus_tag="AC1PIV_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HIP6611811.1"
                     /translation="MKTWKKFAYSCVTLASAAALAACGSLTGNKTASSSTTTEDGLTN
                     ILMYQIGDAPKNIDVLLENANKIIEKEAGAHLDIKYISWGDYKDKMAIITSSGEEYDI
                     AFADNYIINAQKGAYADLTELYKKEGKALYDIIDPAYIKGNTIDGKIYAVPVIGNVAS
                     QQMLSFNQDMVDKYGFDISKVDSYDDVESMLATIKEKEADVTPFAWVKSSKPSTDGLE
                     YPAGNELPFAIDLKGDTTKVVNPFEVDRHMDNLRTIHKYYKAGYIMADAATTDATFSL
                     DVANWFVREETQGPADFGDSLLSTVAGYKITSKPITSAYKTSGSTQVANFVISKTSKN
                     KEKAMEVLTLINTNPELLNGLVFGPEGVNWEKDPSAENRIKLLDGYKGDTRMSAWNTG
                     NSQILYITDKVTDEDVKKAEELLAGAEESPLLGFNFNADAVKTEITSIQNIMSQYAAS
                     INTGTVDPDVAVPEMLKKLEAEESYKKVKEEMQKQYDEFLANK"
BASE COUNT         7881 a         5325 c         6730 g         7631 t
ORIGIN      
        1 taatacgatt atagcaaacg tttacaaaaa aagaaaggag aataagatgg atattgaacg
       61 attgaataca gagcagtcca atccagactc atttgctatt gagacaatgt ctatcgggga
      121 aatcaccgcc tacattaatc gtgaagatgg cctggttgct ttagctgtac aacgtatact
      181 gccccaaatt aatgcagtaa tagaaatagt cgttgactgc ttgaaaaagg atggtagact
      241 gatctatgtc ggagcgggaa cctcaggaag gctaggagtt ttggatgctt cggagtgtcc
      301 gccgactttt ggagtttctc cagagttagt acaaggactt attgctggag gaaatggagc
      361 tgtacgtgcc gccaaagagg gggcagagga taaccgagca gcagctgtag aggatctgca
      421 acaaattggt atatcggcga aggatgtggt tatcgggctt gctgcttcag gcaggactcc
      481 atatgtcctt gaggcagtca catatgctcg tgaaattgga gcaaagacgg ccagtatttc
      541 ctgtgtacaa gatgcggaaa tctccccatt ggtagatgct ccgattgaag tattggttgg
      601 accagaggtt gtaacgggat ctagtcgaat gaaagctggg acagctcaaa aaatgattct
      661 gaatatgatt tctaccacct cgatgataca actaggaaaa gtttttcgag gattcatggt
      721 agatgtgcaa ccgaccaatc aaaaactgat tcaacgagca aaaagaatta tttgtgaaac
      781 aactggctgt acagagatgg aggcggaaca tatttttcaa caagccaacc aagacgtgaa
      841 attagccatc ttgatgcagt tgagtcaact tgatcaaata gaggcaaaaa aacttctgga
      901 aaactatcat aatcacattt catttgcaat tcaatcaatt ttggataagg agaattaaaa
      961 tgaaaaatac gaaagatgtt gcaaagcaag ttcttgaaaa tgttggtggc agggaaaata
     1021 tcctagggaa tgcagtttgt atgacacgac ttcgtttaca gttacgagat gacaagctgg
     1081 ttcaccttga tagtctcaaa aacatagaag gggttttggg agttgttgag gcagatacac
     1141 ttcaaattgt ttttgggcct ggaacagtga caaaggttgg ccaagcattt tcagaactga
     1201 caggtatatc attgggaagt gttgaagaag attacacaac agcggatgtt gctgctacaa
     1261 ataaaaggat aaataaagag aagtacgaca agccagttca acgattcttg caaaaaattg
     1321 ctaatatttt tatacctata ttacctggta taattgcggc aggtttgata aatgggatta
     1381 caaatgtcat taatgtatca accgggaatg cttttgcaat ggaatggtgg tatcaatgta
     1441 ttaggactat gagttgggga ctctttactt ttttgccaat ctatgttgga atgaatgcgg
     1501 cgaaagaatt taaaggaagt ccgattttgg gagcaatggc cggagctatg tctgtggcag
     1561 ttccttcaat gcctttgttg acagtagtgg atgacaaatc aattttatta ccttttgtgg
     1621 acaaggcatt ctcacctagt gcaggcggtt tgttagcggc tctatttgtt gggattttct
     1681 ttgcatttct agaaagaaat atccgaaaat atatgccaag ttttttagac acttttttga
     1741 ctcctctttg tacagtaata ttgggtggtc tggttgcttt gttagtcatt cagcctcttg
     1801 gagaagtgtt aaccacagct atttatagtg gattaaattt tgtatatgag aagctaggta
     1861 tagtaggtgg gtatattttg tcagcaggct tcttaccatt ggtatcagtt ggactacacc
     1921 aagcattgac tccaatacat gttttgttga atgatccatc tgggccaaca ggtggtataa
     1981 attatctctt gcctattttg atgatggcag gtggtggaca agtcggggct ggtttagcac
     2041 tctttttgaa aacaaaaaat aaaaagttga aacaactaac acgagattct attccagtcg
     2101 gaatcttggg aattggtgaa ccgatgatgt acgccgtcac tttgccattg ggcaaacctt
     2161 tcctaaccgc ttgtttaggt tcaggttttg gcggtatttt ggcagtgtta ttccatttag
     2221 ggactgtatc tcaaggagtt tctggtttgt ttggactgtt aatcatggta cctggaagcc
     2281 aactgcaatt tgttatagcg atgctggctg catatgtagg tggttttgta ctaacttggt
     2341 tctttggtgt ggatgaagat agaattgaga ccgtatatgg aagttaatga ttttttcagt
     2401 cgtttcggtt tttcactcta tttatctaac tcatttgcta attcggaaaa gtggtttata
     2461 gaatatcaaa atgcaggatt ttcctttgtt ttctcttcgc ttaatataaa tgaagaagag
     2521 aagggagacg aaaagattcg tcatattgta acaaaatgtc aacgagaagg gctgaccttg
     2581 attgtggata tcaatcaaga tagtttgaag cgatatggga atgaagggat taaaaagctc
     2641 ggtattaaag cacttaggat tgatgatgga attactattg aagtcatgaa atcattgtcg
     2701 gaagactttt tacttgtctt aaatgcatct acattgtcag atgatttttt aaggaagatg
     2761 atggacgttg gtattgagaa aacaaaagtt ttggcatgtc ataattatta tcctaagcct
     2821 tatacaggtt tagggggaag tagtgtccgt gacctaaata gtcggctaca ctcttgtgga
     2881 ataaaagtca tcacctttat tcctggagat aacaagcgtt ttccgctttt tgaaggactt
     2941 ccaaccgttg aagaacatag agcgttgcct ccaattcaag ccgcactcga ttgtttgatg
     3001 tgttgtgaaa gtgattatgt ttgtattggg gataatgcct tatcgagtgc ttcattagaa
     3061 agattttcat atttgacaaa gggtataata gccttatcag cgcagtttcc aaagcaattg
     3121 aagggaatga atttcgaaaa tagaattgat gcagtgaata tgtcatacgt gctagccatt
     3181 caagggctca gttaaaagga tatgcaattc aagggccagc aagtcatcga aaacgaggag
     3241 atattgttct tgctaatgaa cagtttcttc gttatcaatc agaactagaa atttgtttgg
     3301 tcgacttgcc tcaggacgac cgccaaatgg ttgttggcca tgtccatgaa agcgatgtcc
     3361 ctttgttaga ttttgtgaaa catccatttc attttacctt tatataaaac gagtatttgg
     3421 tctgagagtt caataatcgg taacttaaaa aagcctccaa acgatttagt atcattggag
     3481 gtttttatat tacaaatttt caatccaata tcggagcata cgctcgctac tattagggtc
     3541 aatacgggta tcctcataaa ctccaccatt tgcaaggatg gtcttttgag aggcaatatt
     3601 ccaatctgca gcggtgatta agacttgggc aattcccaat tttttagctt ccagcagggc
     3661 aattcgtagt tgttcagtcg catagccttt tcttcgctct tctgggtgaa tagaatagcc
     3721 gatatgacca atataattct ttaaatgctc gtgattaaga tcgtggcgaa tagtgcaaat
     3781 gccaaccatc tgttgatctt tttcacgaat acaaagaaat gtagaagaag gagaacgttc
     3841 tgtatgattt gtcccataag atgacacagc tttaatgtgt tctagccatt cctcaactgc
     3901 ttcaaattgt tgcagtttgc caccaccatg aagatgttca ttgctaaatg cttctttata
     3961 ggctaggatt tggttcttcc attttaaact aggaactaca agatggcaag tttccatttt
     4021 ctacctccaa ctattttgaa tagtttatca tgagtatgtt ttcttgtcaa aaatagtttc
     4081 aggcctttat ttctacctaa aatatgataa aataaggagt atgcgtggtt ttgtgcaaaa
     4141 gagagtgaaa caagcttgtt tgattgtctt ttgtagaaaa cacgcaagaa aaatttcaga
     4201 aaaaatagga gacaattaat gtcaaaacaa gtatttgaaa cggtttttgc tggcaaaaaa
     4261 ttggtcgttg aaacaggtca agttgccaaa caagccaacg gtgcggttgt cgttcgctac
     4321 ggtgattcca cagttcttac agcggcagtt atgtcaaaaa aaatggcgac gggagacttc
     4381 ttccccctcc aagtcaacta tgaagagaaa atgtacgctg ctgggaaatt cccaggtggc
     4441 tggatgaagc gtgaaggtcg tccgtcaact gatgcgacct tgacagctcg tttgattgat
     4501 cgtccgattc gtccaatgtt tgcggaaggt ttccgtaacg aagttcaagt catcaacaca
     4561 gtgctttctt atgatccaga tgcatctgct ccaatggcag ccatgtttgg ttcctcattg
     4621 gcattagcga tctcagacat tccattcaat ggtccaattg ctggtgttca ggttggttat
     4681 gttaatggcg aattgattat taacccagat caagctcaac aagaagcctc ccttttagaa
     4741 ttgacagttg ctggtaacaa agacgctatc aacatggttg aatcgggtgc caaagaatta
     4801 tcagaagaag tgatgttgga agcactcttg aaaggtcatg cggccattca agaactcttg
     4861 gatttccaaa atcaaatcgt ggcagcagtt ggtaaggaaa aagcagatgt ggagcttctt
     4921 caagtggacc cagaattgca ggctgagatt gttgcagctt acaatgacga tttgaaaaaa
     4981 gcggtgcagg ttgaagaaaa attggcccgt gaagatgcga ccaatgccgt tcgcgagact
     5041 gtcattgcaa cttacgaaga aaaatacgct gagcacgaag aatttgaccg tatcatgcgt
     5101 gatgtccatg aaatcttgga actcatggag catacagaag ttcgtcgttt gattactgaa
     5161 gacaaggtcc gtccagatgg tcgccgtgtt gatgagattc gtcctttgga tgcagaagta
     5221 gacttcttgc caaatgttca cggctcaggt ctctttaccc gtggtcaaac gcaagccctc
     5281 tctgtcttga ccttggcacc aatgggagaa acccaaatca tcgacggttt ggatgatgag
     5341 tacaagaaac gcttcttgca tcactacaat ttcccgcaat actcagttgg ctcaactggt
     5401 cgttacggtg caccaggtcg tcgtgagatt ggtcacggtg ctctcggtga gcgcgctctt
     5461 gagcaagtct tgcctagctt ggaagacttc ccttacgcta tccgcttggt agcagaagtc
     5521 ttggagtcaa acggttcttc ttcacaggca tctatcacag ctgggaccct tgcccttatg
     5581 gcaggtggtg tgccaatcaa ggcacccgtt gcagggattg ctatgggtct gatctcagat
     5641 ggtaccaatt acaccgtctt gaccgatatt caaggtcttg aggatcactt cggcgacatg
     5701 gacttcaagg tagctggtac tcgtgacggt atcacagccc ttcaaatgga tattaaaatt
     5761 gacggtatca caccacaaat cttggaagaa gccttggcac aagctaagaa ggcacgtttt
     5821 gaaatccttg atgtcatcga agcgactatc ccagaagttc gtcctgactt ggcaccaact
     5881 gcaccgaaga ttgacactat caagattgat gtggacaaga tcaagattgt cataggtaag
     5941 ggtggtgaaa ccattgataa gattattgca gaaactggcg tgaaaattga tatcgacgaa
     6001 gacggtcttg tggcgatctt ctcaccagac cgtgctgcaa ttgagcgcac aaaagaaatc
     6061 atcgctggtc ttgtccgtga agcaaaagtg gacgaagtct tccaagcaaa agtggttcgt
     6121 ttggagaaat tcggtgcctt tgtcaacctt tttgacaaga ccgatgccct cgtccacgtt
     6181 tctgaaatgg cttggacacg tgtcaataaa ccagaagatt tggttgaggt tggcgatgtt
     6241 gtagatgtta aggtgataaa aattgatgat aagggacgta ttgatgcttc tatgaaagct
     6301 cttctaccaa aaccagaagg ctacgtggaa ccagaaaaac gtgaacgttc agaaaaacct
     6361 cgtcgtcata aagaacacaa agagaaaaaa gataataact ttggtgaatt taaatttcat
     6421 aaagtagata aaaaataatg gtgaagtagg caagtcccga aatggacttg tcttctcgct
     6481 agaaggagaa gtcatgggtt ggtggaagga taccatagaa attgtaaaag aaaaagatcc
     6541 ggcagcacgg aactccttgg aagtcctttt gacctaccca ggagtcaagg cactggctgc
     6601 tcatcgtctc tctcactgga tgtggcaaaa tggttttaaa ttattagctc ggatgcacag
     6661 tcagttttgg cgtttttgga ccaacattga aattcatcca ggtgcagaaa ttgcctcggg
     6721 agtctttatt gatcatggcg cgggattggt aattggtgag actgcaattg tcgaatctgg
     6781 tgtaatgtta taccatggag taactcttgg aggaacaggc aaggatacag ggaagcgcca
     6841 tccaacagtt cgaaaagggg cactcgtttc tgctcatgcc caggtgattg gcccagttga
     6901 aatcggagaa aatgcgaaag taggtgctgc tgctgttgtc ctagccgatg ttccagcaga
     6961 tgtgacagtg gtcggtatgc cggctaaaat cgtccgtgtt catggtcaaa aagatgagaa
     7021 gatcattcat gacatggaag atggtcgtga acactacacg acaaaattag cagagttgag
     7081 agaagccagc catcgttcgt cgcatttgta ggaaagaagg ctgatatgct actagaagaa
     7141 tttgaaaaca cctctgcagt tattgaacca acggacaagg ctatccgtgg tggtggagag
     7201 gtatgtgaga cgatgatttt ctccttcaat ggagaaatcg tggaccgagt aagtcagcta
     7261 gctgaaagca gggaaggtgg tcatcttcag acgttaaatg gtcgccatcc ttggtatatt
     7321 ttggaaagag atggactgca ggttgcggtc atgttggcag taatcggtgc tccaatggca
     7381 gttggtcatc tggaagagct gaaagcctgt ggctttgaga attttatcgt tctgggttct
     7441 tgtggggtgc tggataagtc gctcgctgcg gataagatca tccttcctag ctctgctctt
     7501 cgggacgagg gaactggtta ccactacgca cctgctagcg aggaaatcag ctatgaccct
     7561 gctctgctat taaccatgga aaaggccttg gaccaagcgg gaatcgagca cgtgcgggct
     7621 aagacctgga ccacggacgc tttctttcgg gaaacagctg ccaaggtcaa gcgtcgccta
     7681 gccgctggtg ccatggtggt cgatatggaa gcttctgcta tcatggcctg ggcaaacttt
     7741 cgtcaggcca aggtctacca atttttctac acggcagact atgtggacca ccacaagaat
     7801 gaatgggatg cccgtcgaga ggaacggatg gctgacagta tgaccttctt tgaagtggcc
     7861 atggccattg caagaaaatt agaaagtaga tcatgttaaa aaaattagta agacaaaact
     7921 ggccttatgt gttgaccgcc atcgctggga caatcatgtt tatccttaaa ttctcccaag
     7981 gaagctggca ggtagggatg atttggttgg ccgcgacagc ttattggcta gtaaaattgt
     8041 atcaaaagta tcaagtccta aagaatactc agaagtaatg gagaaactat gattaaaatt
     8101 tacgatacca tgactcgcag tctgcgtgac tttgtgccct tggaagaggg taaggtcaag
     8161 atgtatgttt gcggtccgac ggtttacaac tatatccata tcggtaatgc ccgtagtgtc
     8221 gtggcttttg ataccatccg ccgctatttt gaataccgtg gctatgatgt gacctacatc
     8281 tcaaacttta cggatgtgga tgacaagatt atcaaagctg ctaatgaagc aggcatgaca
     8341 accaaggaac tgtctgataa atttatcgca gctttcaagg aagatgtgac aaaactgggt
     8401 gtcaagccag ctaccaaaaa tcctcgcgtt atcgactaca tggatgaaat catcgatttt
     8461 gtgcaggtct tgattgacaa gggttacgcc tatgaagcgg ctggcgatgt ttattttcgt
     8521 gtggaaaagg tggagaatta tgctcgtttg gccaacaaaa ccctatctga cttggaggtt
     8581 ggggcttctg gtcgtgttga gggagaaggt caattgaaag aacatccttt cgattttgcc
     8641 ctgtggaaaa ctgccaagtc aggcgaagtt tcttggggaa gtccttgggg agcgggtcgt
     8701 ccaggttggc atatcgagtg ttcggtcatg gcgacagaga ttttgggagc taccatcgat
     8761 attcacggtg gtggtgcgga cttggaattt cctcaccata ccaatgaaat cgcccagtct
     8821 gagtgcaaaa caggtcaaac ctttgccaac tactggatgc acaatgccat gctcaacatc
     8881 aatgatgaga agatgtccaa gtccttgggc aatttcctga cagcccatga tatgttggaa
     8941 caaattgatg gtcaggtctt gcgcttcttc ctagccaccc agcactaccg ccgtccactc
     9001 aactacactg agaaggctat ttcagatgcg gaaatcaatc tcaaatatct aaaaaatact
     9061 tatacacaac ctgtgcaaaa ctctgtggat aagtcagctc ttgaattaca tctggcggcc
     9121 tttgaagcag ccatggatga tgatttcaac gcagcaaacg ggattacggc tatctttgac
     9181 tttgccaaat ggatcaactc aggcaactac gatgaaactg taaaagaagc ctttggcaag
     9241 atgctcgccg tctttggtat tgtttttgaa gaagaagtct tggacagcga gattgaagcc
     9301 ttgatagcag aacgtcaagc agcgcgtgcc aatcgggact ttgcgacggc tgaccgtatt
     9361 cgtgatgaat tggcagctca gggcatcaag ctcttggata ccaaggatgg tgtgaggtgg
     9421 acacgtgact aaggcagtag atgtcaatct catcaatgga attgctctgg cttttgaagg
     9481 ggatgctgtc tattccatgt atatcagacg gcacttgatt ttcaagggac tgaccaagcc
     9541 taacaaattg catggcgagg ctaacaaata cgtctcggcc aaggctcagg caggcttgat
     9601 ttctgccctc ttagaagctc agctattgac cgaaaaagag gaagaaatct acaagcgggg
     9661 gcgcaatacc aatagccata ccaaggccaa gaatgcggac gtggtcacct atcggatgtc
     9721 cacaggcttt gaggcggtct tgggctacct gcacatgaca gagcagatgg aacgcctgga
     9781 tgaactggta ggttggtgta ttaagtttgt agaaaataat taacgaagac aacgaggagg
     9841 gaaacttcct cttttttgtt ttctctaaac taaagttctt tttatctgat ttaaagaagg
     9901 gaaccatgag ggcttgaagg tcatattttt cctctgtaca atggaattaa taaaacctga
     9961 taaacttcgt gtgatagctg ttctatcaaa ggtagcatgt gccaactatg atctggaaag
    10021 gaggaaattg agaacagctg ttgcactaca attgtgtagg aggaaaatat gacaaaatgt
    10081 gatttcgaca aacgtcagcg attcggtatt cgaaaattta caataggtgc ttgttctgtt
    10141 ttgattggtg cgaccttatt tggaacacag gtttctgcgg accagctaga aaatgtggac
    10201 agcttgtcag agccagctgt tgaactctct tccgtagtga acgaacatgt ggaaaagacc
    10261 gaagctgaag aaggaatgtc accaatttca gcagacgaga aagcggtgac cgaagagttg
    10321 aatggagaag catctgtatc agatagtaga gaagaaaaac tgccttcagc tccgtctgat
    10381 aatccagaaa ataaactaga ggatacagag gaagcggaag ataaagaggt agattcttca
    10441 gattctggtc tgttgctttc agattttcct caggtagagg atcaaggaat tcgtccgaaa
    10501 gagattaagt ttgacaactg ggatcaggtg cttgcttggg agccgggtgc tcgtccagat
    10561 gatgatttga accgcgcttc tgtagagttg gttgagcgct ttagagggca cgtcgtcaat
    10621 gagagagcca atgagaatgc aaaggtagaa gctctttcaa ataccaactc taaggcgaaa
    10681 gaccatgcct ctgttggggg agaagagttt aaagcctatg cctttgatta ctggcagtat
    10741 attgattcaa tggtattttg ggaaggcttg attcctagcc cagacgtcat tgatgctgga
    10801 caccgtaatg gtgtgcctgt tttgggaacg attttctaca attggtccag tagtattgaa
    10861 gatcaagaga agtttgtatc ttctatgaga caggatcctg atggaagttt tcctgttgct
    10921 cgtaagttgg tagatatggc taaatactac ggtttcgatg gttatttcat aaatcaagag
    10981 actacaggag gcttggttca accactaggg gaaacaatga gaaacttcat gctctatacc
    11041 aaggaatatg cagaatcgat tggttatccg ataacgtatt cttggtatga tgccatgacc
    11101 tacgaatatg gtcgctatca cgaagatggt ttgggtgagt acaactatcc gtttatggaa
    11161 aaggaaggag acaaggtccc tgcggatcat ttctttgcga attttaactg gacacgggcc
    11221 aaaaataact attcaatcga agtggcgaaa cgaatcggtc gaaatccatt tgatattttt
    11281 gctggatttg aattgcaacg gggaggctct tacaaaacgc aaattaactg ggatgctctg
    11341 tttgatgaaa acgggaaatt gaaattatca ctcggtctgt ttgcgccaga taccattaca
    11401 agtttgggtg cgacgggtga ggattatcat gagaatgaga atatcttctt tacaggctat
    11461 caaggtgatc caaccaaaca gaaaccttcg gataaaaatt ggtatggctt ggccaatctc
    11521 attgcggata agacggctat tacaagcagt aatttcaata gttcctttaa tacagggcac
    11581 gggaaaaaat ggtttgtaga tggcaaggtt gccaaagatg gggaatggaa ttatcgttct
    11641 gtgtctggta ttttaccaac ctggcggtgg tggattgaag caagtggtga aaagcttgct
    11701 gcggcttatg attttgatga tgcctataat gggggcaact ctcttcgttt tacaggcgat
    11761 ttggaaaaag atggtaagca ggaaattaag ttgtattcca ccaagattcc tctatcagaa
    11821 acaagtcgtt tacgggttgc gcacaaagga gggcaaggtg caaatatctc cctagctcta
    11881 gcgcttgaac cagattatca atttgcgaat aaagaagcgt ggcgcttgct taaactatca
    11941 ggagattggc aagatcagac ctttgattta tctagtttgg caggaaagac agtgtacggt
    12001 atccaagtgg ttgttgaaaa tgaagcagcg ctgtcagatt ttgattttcg tttagggcag
    12061 ttggctattt atgaccaaga aaattcacct actgcaccga aagatggcca agtccttgct
    12121 aagcgattga agaatgccca agatgctgaa gctgtgatta gctttacagg gacagatgat
    12181 gcagactatt atgaagtata tgcgcaggtt gacggacagt ggaaattgct gacaggttct
    12241 tctaatacaa ggatttacct ccctcaacta gttcgttctg cacaggcaga aggtcgaacc
    12301 caagctttga aagttcatgc cgttgggaaa aatggtttgc gttcggaagc aggggagttt
    12361 atctttgatt gggagatgac ggtgaaagat actagccttc ctaaaccatc ggcagaaaac
    12421 attgttctcg gagcagaagt catcggttca agttttgcta aaaaagaagg tggagaaggc
    12481 attgagggca tgttgaatgg gaccattacc agtttgtcag ataaatggtc ttcccatcaa
    12541 ttgagtggcc atgtagatat tcgtttgacc caacctcgga cagtcgtgcg atgggctatg
    12601 gatcatgctg gtgcaggtgg tgaatcggtc aatgatggct taatgaacac caaggatttc
    12661 gatctctatt ataaaaatga gaatggtgat tgggtgttag ccaaagaagt tcgtggcaat
    12721 cgtgatcatg tgacagacat cgtattggac aagccaattc gagcgcagga atggcgtttg
    12781 gatgtcttga cttctgataa tggtactcct tggaaggcca ttcgtattta taattggcgt
    12841 atgtatgaag aattggacat ggagacacca aatattccga tgacccatgc tgttgctcgc
    12901 catctcggta atcatcagat tcaagtaggt ttcaaggatg tccctgccaa tcggaaaata
    12961 gcgctttatt ctagtccaga tgccgtaaaa ccactagcag aattggaaac gacagagtca
    13021 ggaaatctta tattcgaccc gattcgcttt gagtccctgc ctgagttcat ttactaccgt
    13081 actctggagg aaggaaagga ttggagcaat ctattggcca ttcgcgttcc gcaaggtgaa
    13141 aaagtcgtga aagcgatgga atggatagct cccctagaga aaaaagttta ccgacaaggt
    13201 agtcctttat cgcttgcagg agcacaattc cgtgtagttt ttgaaggaga ttggcctgct
    13261 gaacgggtga ataccaccaa tccggcagtt acagtaaggg gatttgatcc gcaaaaatta
    13321 ggtgaacaaa cattgaccgt ttcctatcta ggagaaacac ttgctcagcc actgatggta
    13381 tatgttgttg aagatatagc ccagggtgag aaaaaagcag tcggtctaga aatccaacag
    13441 ttaccaaaag tgcagtatgt tgtaggagat gatttggatg tcacaaatgg tcgatttgct
    13501 attatctatg acgatgagtc aactcagtcc ttctctttga cagaagctgg agtagaaatt
    13561 gttggtttcg attcccgtaa agaggggcgt cagagcctag gtttgcggta tgctggtttg
    13621 gagacttcat ttgatgtcct tgtttcaccg aagccaatcg tcaatgatga gtatctaaag
    13681 cagaaaatag cagaaattga ggctctacaa acccaaacag cctatctcta ttctagtgag
    13741 cagacacaac ttgccttgca aacagccttg gaagaagcta agtctgtggt agcagatacc
    13801 aatcggacag tcgagcaggt tgaagccgct caaactcttt tagagaaaca gttaggagag
    13861 ctggatgggg agaaacttta ccaagcagat cttgggcgtc tcaatcagct aatccaagag
    13921 gtgaaaggaa tagatagacc tataaattct tctgagctaa gttctttact tgaaaaaact
    13981 gagaaaattt tgggttcgga tagtattcgt ccagatgaga tgaaggagct gctcagtgaa
    14041 tggactgatt tgtttgaaca gtctagtctg gtaactcatg tcggtacaag agattcgatg
    14101 gagtctaaga atttactagc tcctgaaaaa ccgagaatgg atttgaccta tgagctggtg
    14161 ccgagacaaa tcatcacaca gaccagcact gatttgccac tgggcaaaga gcgaattgtt
    14221 caggaggggg ctgatggtca aatgatgata gctcacctag tctatagtga tggccgtcgc
    14281 gagctgtatt cacgaatagt tgctgatgag agtcagccga aaatagtgga ggtcggcagc
    14341 ggtttgccta tccagcaaga gaagacttta atggtggaaa atagcctgca ggttgaaaag
    14401 cagatcagag atgcttctct gcagaagagt ggtcttccac aaactggtga tacctatcag
    14461 gagaagtatg tctttcttgg gttaattggt gtggctttgg ctggcctatc tcagttagct
    14521 aagcttagaa agcaaggtga ataaaagaaa tagtcaggct tggtcctgac tatttctttt
    14581 gtttgtagaa gctggttagt tacttggtaa tatagatagg tcaaattcta ggcagtttga
    14641 ttttatcagt tggtcatgtt tgatggtttg gacgacttgt ttgtctaatg aaacttgctt
    14701 gacaaactgg aaatttgcat cgctttttgg agtagaaatg gtcagcttgt gttgatctgc
    14761 aagtagcaag tctacttcct taaaatgcgg tagtccgatt tggtagtcag cttttccggg
    14821 acagacagga tagaagccta gacaggagaa aatataccag gctgaaaggc taccgttatc
    14881 ctcgtcacct ggataggctt gaaaacctgt cttgaaagct gtttgtctga ttttgtgaat
    14941 gagtagacta gtgtattccg gttttgtaga ccattggaaa agataaggga tatggaagct
    15001 cggttgattt gaaatagcaa gctgaccgag attgacttgc gccatttccg acatttcgtg
    15061 gatttcgtag ccgtattgtt caggtgagaa atagggctcc tgattacaga gctggattag
    15121 atagttggtg aaggcttctt ttccgcccat caattctatc agtccatcga tgtcatgaaa
    15181 gacggacagg gttgcctgta gggcagaaca ttcggcatag tctcttcccc aacttagagg
    15241 ggaaaaatct gctcggaatt gtttctgtct atccttggca cgcatgagac ctgtttggct
    15301 atcgaataac tgtcggtagc cgaggcacat ttgagcgtat tgcttagcca gttggtcctg
    15361 cctcagtttt tctgctactt ggctgatagc ccaatcactg taggcataat caagagaatg
    15421 gctcacagat tcgttgaaat cgagagggag atagcctaat tggcggtaaa tctgactacc
    15481 atggcggccg taacgttgat ccgcatcggt cttttgactg gtttcaatca tggcttggag
    15541 aaaatcttcc atcaaatcag gaacaagtcc cttgcaggcc gcatcagcaa tgactccatc
    15601 cacaagagtt cctggcatga taccgcgctc gtctggcgat agccatttgg gtaaaaatcc
    15661 agtatctcga tagtgttgga gaatgccgtg gagaaactct tccaaataat ctgggtagat
    15721 aagtgaaagc aggggataag aagagcggaa ggtatcccag tagccgttgt tggtgaaaaa
    15781 cttacctagc ttggcctgat tgctgatagg gtcgaaatga atggcttgtc cgtcaggatt
    15841 aggttcgtag aaagtttgtg gatagaggag gcaacggtag aggcagtggt agaagaagtt
    15901 aatgtcctct gtttttttgt cacgaatctg aatacgtcct aagagctgat tccaggtgtt
    15961 ttctgcttgt ttttgggctt gaaggaagtc aggaacatct tttaatagaa aggcggcttg
    16021 ctcagggctg ataaaagagg tagccaaacg ccccttgata gaagtgcttg agaagttgat
    16081 gcgaaggtgc aaatcttctc ccaccacttc cgttttagct atcttgcgat ccttgaccag
    16141 atgataacat tctgttattt cctcttcaaa ttctaggaga gcatacatgc agaaatcagg
    16201 ggattggcag gcgctgacct gaaaaatctg aatgagcaat tggtgaggat tgagcagtcg
    16261 ataaatggat tttccagatg aatagaagac cattccgata ggctggttag caaaagacgc
    16321 tatctcaaaa ctggctccgt atcggctggg agctaaacgg cttatcaagc gatagcgatt
    16381 ggattgtaat tgaaggagat caggtcggaa aatagcctga tccagttggt agctagattg
    16441 acggtgaaag aggctatctc ggcttaattc gcctgtgaca ggcgtcaata ggagggaggc
    16501 aaaatctccc aaccaaggac tgggttgatg ggttaagcga atgccctgat agacaggttc
    16561 atagggattg aaccaccagt ttccagtctg gtcgctggtc tggggagcaa aataattcat
    16621 gccgaaaggg acccctatca atggcagggt gtttccgttt gaaaaggcat gtgagttata
    16681 agtaccatag cgggtgtcaa tggttgaaac aatggaggta tacataggct atccttttct
    16741 ttttttattg ataataagtg gtgttctcct tattatatag agaatgggaa agaaaggaaa
    16801 tcgttttccg aaactggcaa tatttgtgta aaaatgcgtt taatttgtgt ataggatttg
    16861 catatagaat tgtatagact gatactagga accttgtgtc taatgaaaat tatatggatt
    16921 tgccagatag aggttggaag aactctgagc aaaggataaa aaggagaaat catgttttac
    16981 acaaaagaaa tcatagagaa ctggctgaca ggcattcaga agaaaacagc agaccaccca
    17041 agttggggga gtgtatttga aaggtgttat acggatacgc ttgataggac cattagtcag
    17101 ctggaagatg ggactacttt tgtcttaacg ggggatattc cagccatgtg gttaagggac
    17161 tcgacagccc aggtcaaacc ctatttagct ttggctagaa aagatgagaa attacgccag
    17221 atgattgtag gtctggtaga gaggcaaatg gcctttattt tgatggatcc ttatgccaat
    17281 gcctttaatc aggcagctaa tgggcggggg caccagaccg accacactca gataggcccc
    17341 tggatttggg agcgaaaata tgaggtggat tccctctgct atccccttca attagcctat
    17401 ctactttgga aagcgacagg ggaaaccagt cattttaacc agaccttctt tggggcagct
    17461 gaaaaaattg ttcaactctg gaaattggag cagcaccatg aaaactcccc ttatagtttt
    17521 gaacgggata cagaccggct agaggatacc ctcacgcacc aaggaaaagg ggctccctgc
    17581 gcctatacag ggatgacttg gtctggtttt cgtccaagcg atgacgcctg tatctaccct
    17641 tacctcatcc cctccaacat gtttgcggtc gtcgtcttgg gttatttagg agaaatagca
    17701 gagcagtttg caagtgagga attctcagat ttggctgaag gtgccagacg gttggcgcag
    17761 gaaattgacc aggggattcg gaccttcggg ctgaccaaga atcaggcggg agaaactatt
    17821 tttgcctatg aagtggacgg attgggcaat cagtctatca tggatgaccc aaatgtcccg
    17881 agtttgctgg cggctcccta tctaggatac tgtcagaaag atgatcccat ctatttggca
    17941 acccgtcgga ctattttaag tcaagaaaat ccctattact acgagggaga ctatgctgcg
    18001 ggtcttggtt ccagtcatac cttctatcgc tatatctggc cgattgcctt ggctattcaa
    18061 ggattgacaa cggatgacaa ggaagaaaaa gcgcgcttgc tggataccat ggtagcctgt
    18121 gatggcggta ctgggctgat gcacgagagt ttccatgtgg atgatccgac gctttactct
    18181 agagagtggt tctcctgggc aaatatgatg ttttgcgaat tggttttaga ttattatgat
    18241 atacgaccgg aggaataaaa tgggaaaaga aacggttcat attatttcac atagccactg
    18301 ggatagggag tggtatcttc ctttggaaga acatcggatg cgcttagtag agctatttga
    18361 tgacctgttt gacttatttg aaacagatcc tgagtttagg agttttcatc tagatggaca
    18421 gaccattgtc ctagatgact atctggaaat tcgtccgcag aatcgagagt tattgaagaa
    18481 atatattcaa gacggtcggc tgattattgg tcccttttac atcttgcagg atgattacct
    18541 catcaccagc gaggccaata tgcgaaatac ccttctgggt catttggaaa gcaagaagtg
    18601 gggacgggct ccgaagattg gttattatcc agatactttc ggcaatatgg gacaggctcc
    18661 tcagctactg cgtcaggctg gtatagatgt ggccttgttt ggtcgtgggg tcaaaccagt
    18721 tggctttgat aatcaggttc tgggagatga ccaattccag tccactttct cggagatgat
    18781 ttgggagggg gcagatggca gtcaggttct gggcatttta tttgctaact ggtacagcaa
    18841 tggcaatgaa atcccagttg atgaggagga agcacgtgtt ttctgggaga aaaaattggc
    18901 agatgttcgc aaatacgctt caacctccca ctatctgctg atgaatggct gtgaccacca
    18961 gcctgtccag aaaaatctca gccaagcatt acgactggcc cgaaaactgt atccagatat
    19021 agactttgtt cattcaagct ttgaagaata tatcgcagct gtcaaggaag agttaccagt
    19081 agacctcagt cgtgtcaagg gagaattgat tagccaggaa acggatggct ggtacacctt
    19141 ggcaaatacg gcttcttcga gaatttatct caagcaggcc aatgaccaag ccagtcagct
    19201 cttggaacaa gttgtagaac ccttggtggt aatgacagga gataaggtgc ccagagatga
    19261 gttgcgctat gcctggaaac tcttgttgca gaatgcccct catgatagca tctgtggttg
    19321 tagcgtagac caggtgcata gtgagatgga aacccgcttt aagaaggtca agcaagtcgc
    19381 tcatttcttg agccagcgct ccctagacag gtgggaaaag caggtggatt ctagccaatt
    19441 agacggctta ctatttacgg ttttcaatac tacagcctgc cgacaaaccc agttagtgga
    19501 ggttgatttg cttgttgaac aggaggattt ccgagatggg cagttagaac aacactttca
    19561 atccatggca gctatttctc tgccagcctt gggcctcttt accagtcaag gccaagaggt
    19621 agaagctacc attgaagatc taggtgtcaa cttccgctac gatttaccaa aagatgcttt
    19681 tcgctctgcc aattttgccc gccagattcg tgtccgcttt gtagtggaaa atcaagcacc
    19741 attttcatgg cagacctatc aagtcaagcc gattggtgac actagggtga atagcagttt
    19801 aagtgaacag ttcgagaatg attattaccg tatcaatgtg atggatggtc agctcttgct
    19861 agaagataag agaacgggtc aagcctataa agactggcta cggtttgaag attgtggaga
    19921 tttgggcaat gaatatatct tcatggcgcc taagaatgac caaccgatct atggtcagat
    19981 agagtacttc ggtcttgtct accaaacaga agcggtcagc attgccaagg tcatgcaccg
    20041 tctgcagctg cctgtagcta tggaaacaag tctggaagat gaacagaagc gcctggtaga
    20101 atttaaacat cgaacatctc aaaggagtca ggaaaagaaa gacctgctcc ttaccaccta
    20161 tctgacactc taccgccacc aatcccaaat tcgcatccag accgatttcc acaaccaaat
    20221 caaggaccat cgcttgcgag cagtctttga tattggaata gaagctgaga accacttggc
    20281 ggattccatc tttgaagtcg ttgaacgtcc aaatcagcca catccagcct gggaaaatcc
    20341 gtccaatcct cagcgtcatc gcagttttat tagtctatca gatggtcgac aagccatgac
    20401 cgtttcgagt aagggcctac atgagtatga aatcctagac aagggaaaaa tagctcttac
    20461 cttgcttcgt gcgactggag agctgggaga ttggggctac ttcccaacac cagaagccca
    20521 gtgtttgagg gaatgtcagt tggactatgc ctttgaaatt tgcccagtag aggaaggttt
    20581 tgccagcttc caaagagcgc aggccttcca aggacacttg ctaactaaac agttgactag
    20641 ccatagtggg catctgccgt gtgatcatca gtttttgagc catccagcac tggaagagga
    20701 ccgcttatgc gtgacttctt tgaaggtggc agagacttcg gaccgcattc tgctccgtta
    20761 ctacaatatg agtcaggagc agttagcagg ttggagcgag tggactgagg gggttgattt
    20821 gctagaagaa ccactagagg atttgccggc taggattggg tcacaggcaa tccgaacaga
    20881 ggtcgttggt catcatggaa aggagaaaga acatggtagt agcctgtttt gacattggtg
    20941 gtacgggaat aaaggcggcc ctgattggtt cagataagca gataaactat aggcaggaat
    21001 ggaaaacgcc atctagttta gcggaattgt tggcgcttat ggacagtgtt attcagccgg
    21061 tagacggctt ggaggctatt tccctcagta tacctggagc ggtagacctt gaaacaggtg
    21121 tcatccaggg gctgagtgcc gttccttata tccatggtgt atcttggtat gagctattaa
    21181 gtcagtatgg ctgtcctgtt tatttggaaa atgatgccaa ttgtgtcggt ctgagtgaat
    21241 tggctgttga tgaccagtta tcgacttttg cctgtgtcgt ctgtggtacg ggtatcggtg
    21301 gtgccttgat tgtggataga aaactcatcc gagggaaaca aggtttcggt ggcgaatttg
    21361 gctatatgct gattgctact ggaaagggac ctctaaaaaa ctggtcccaa cttgcttcta
    21421 ctggaagttt ggtcagacag gttgctagtc agtatgagga agctgtggaa gattggaacg
    21481 gcaagcggat ttttgagcta gcagaacagg gagatgaggt atgtcaatta gccattgaag
    21541 aaatgacacg caatctggcc tatggcattt taaatatctc ctatttcctg gaaccagaag
    21601 tgctggctat aggtggctct atcagccaga atccagtctt tatccaagct attcaggagc
    21661 aactagaggc tattcaaaag gaatatccag aagaatttcc ttatctacct gccattcgtg
    21721 cctgccacta ccagcaggat gccaatctca tgggtgctta tatgaagacc ctacaataag
    21781 gagaaatgat gatgttacag ataaaccatt cgttacggca gtcggagggg gtcttggaag
    21841 agatttgttc ctcgcttggc ttggattgcc agttagaact tgaagtcggt ggcaaggaga
    21901 gtttgcggat tgaaggttca gcaggttctt accgtatccg tgcgcctaaa gaacacatga
    21961 tttatcgagg cttgcttgtt ttggctagtc agttggctca gggtgagacc gacatacaga
    22021 ttctagaaag acctgcctat cgtcaactcg gttttatgga agattgttct cgaaatgctg
    22081 tcctgacggt tgaagccagt aaaatcttga ttagacaatt ggccttgata ggctacagcc
    22141 atttccagct ttacatggaa gatacctacc aactacgtga tgaaccctat tttggttatt
    22201 tccgaggggc ctatacaaaa gaagaattgc aggctattga ggaggagtgc caccgttacg
    22261 gtatggaatt tattccctgt atccagacct tggcccatct gatcgcctac ctcaaatgga
    22321 acatttcatc tattcaggcc attcgagatg tggataatat tctcttgatt ggggatgaga
    22381 ggacctatgc cttgattgat aagatgtttg aggctttgtc ccatctgaaa acacggacca
    22441 ttaacatcgg tatggatgag gctcacttgg tcgggctggg tcaatacctc aatcaacacg
    22501 gctatcagaa acgaagtctg attatgtgcc aacacttgga acgggtcttg gatattgctg
    22561 acaagtacgg cttccattgt agtatgtgga gcgatatgtt cttccagttg ttgacagcga
    22621 gtaaggatta tactggtcag ttggaaattg attcggaaat tcaggcttat ttggatcgtc
    22681 tcaaggacag agtgaccttg atttattggg attactatca gactagtcgt gagagctatg
    22741 gtcaaaaact agctagtcat cagcagttgg gagatcagat tgcctttgca agtggtgcct
    22801 ggaagtggat tggttttact cctgataatg atttcagtat gcggattgca ccaaaagcac
    22861 atgctgcctg ccaagagtat ggcgtccaag aagtgacggt gaccgcttgg ggagataatg
    22921 gtggagaatg cgcaaccttt tcgatcttgc cgagtcttca tgcctgggca gaactccagt
    22981 accgaggaaa tttgggctgt ctggctgagc atttctatca actacaccaa gtttccctag
    23041 atgacttcct gcaattggat ttgccaaata agacacctag tcacccaggt ccaggtcatc
    23101 acggtttcaa tcccagtcgc tacattttgt atcaggatat tctctgcccc ttgctgcaag
    23161 agcatattga tgccgaaaaa gacaatgcct tttatcagga attagcgcct agattggcag
    23221 agattggaag ccgagccaag ggctatgcct atctctttga tactcaggct aagttgtgtc
    23281 aggttttagc gaccaaggcg gctatttcag taggtattcg tcaggcctat caggaaggaa
    23341 atcgtcaggt cttggcagag aaagttgacg gtttgcagca actaagaata gatctggaaa
    23401 gcttctatca ggcacttagc taccaatgga tggtagagaa gaaggtgttt ggtctggata
    23461 cggtggacat tcgcctaggg ggattggata cccgcattcg ccgagcaatc cagcggttgc
    23521 aagcctatct gaacaatgaa gtacctaaac tagatgaact agaagtgcca attctccctt
    23581 acgatgactt ccatcaggac aagggattta ttgcgacaac tgccaaccaa tggcagatta
    23641 ttgcgacggc ttcaaccatc tatacgacct agtagttctc gagctcgaaa gggctcaatt
    23701 ttttatgcaa attttgatta gcaacccaga ttttctttgt tttttacaga aggtatatcg
    23761 gttgttatat acacctataa tttgtagaat tttgcctata atgtggcaat tcacagttgg
    23821 cccaatcagg agtaaactaa taatgtaaag gttcataata gaaaggagct atgatgaaag
    23881 acctcataaa aaatctaaaa caaaatgcca tttttttcct aatggtattg ccaggagtca
    23941 tctggctcat tctatttttc tatattccag tatttggcaa tgtgattgct tttaaggact
    24001 atcgccatac aggtaatggc ttttgggata gtctcataca aagtaagtgg ataggattgg
    24061 ataattttaa atttctattt caatcatccg atgcctatat catcacaaga aataccatcc
    24121 tatataatct tggttttatc gtactcggac tgatttttgc agtaggtatt gccattatct
    24181 ttagtgagat gcggtcgaag aagctggtaa agatctatca gaccacaacc ttgttccctt
    24241 atttcctttc ttgggtcatt atcagtttct tcgtttacgc atttttgagt ccagataaag
    24301 gattgataaa caatattctc aaaggaatgg ggatggatcc catcaactgg tacagcacac
    24361 caacctattg gcccttcatc ttgcttttct taggaatttg gaaaggtttg ggctataaca
    24421 gtattattta ttatgcaacc attatgggca ttgacccaac ctactatgaa gctgcgattg
    24481 tggatggagc gaccaaatgg caacgcatcc gctatgtcac ccttcctcag ttaatgcctc
    24541 tgatgactat tttaacgatt ctggctgtcg gaaatatctt ccgagcagac tttggccttt
    24601 tctatcaaat tccgaaaaat tcaggtcctc tcttcaatgt gactcaggtc cttgatacct
    24661 acgtttatcg tggaattgca ggaacagggg acatcggtat ggctatcgcg gcaggtctct
    24721 atcagtctgt tgtcggctgt atcttggtgg tagtgaccaa cctgattgtt cgtcgctttg
    24781 ataaggaatc agccttattc taggagggga gtatgaaaaa aaagaaacaa atcacttctg
    24841 tttctattca ttcatttagt aagaaaacag atctattttt ctcaagttta ctagggatat
    24901 ttgccctatc ttgtaccctt cccttcatat ttgttatcat catttctatg acagatgaga
    24961 caagcttggc tatcaacggc tattctttct ggccagagca atggagtttg gcaggttatg
    25021 aatatctctt tcaattaaaa gatcagattc tccaagccct ctttatcacc ttctttgtga
    25081 ccattgtagg gacgagcctg aatgtcttct tcaccgttct ttacgcctat gccatttcga
    25141 gaaacagttt cagatacaga cgatttttta ccctgatggc tctctttacc atgctgttta
    25201 gcgcagggac cattccaacc tatatcgtta tgacctcgtt tttaaatctc aaagatacag
    25261 tggcagcctt gattctacct atgctgctat ctcctttcaa tatcatggtg atgaggtcct
    25321 tctttagaaa gactatttct gagtctatta tcgaatctgc caggattgac ggggccagtg
    25381 aatttcggat tttcttccaa atctgcttgc cactaaccct accaggtatc gcaacaatcg
    25441 ctctctttac agccctcgct ttttggaatg actggtacaa cgctctcctc tatatccaga
    25501 gcgataacct cttccctctc caatacctgc tgatgaaaat tcaagcaaac attcaatatc
    25561 tctctgaaaa tgctgccgca gcagcggcca tgtcctcaga agttgcaggg gcccttccca
    25621 aagaagcaac acgtatggct attgtggtcg tatcgactct accaattgcc tgtctctatc
    25681 ctttcttcca acgttacttt gtcaaaggtt tgacaattgg cggagtcaag gagtagagac
    25741 atcactctat cttaacaatc gtattccata cttcattatc taaaaaaata gaaaggaaca
    25801 gccaaatgaa aacatggaaa aaatttgcct actcctgcgt gacacttgcg tccgcagctg
    25861 cccttgccgc ttgtggtagt ctgactggaa ataagaccgc atcaagtagc actacaacag
    25921 aagatggatt gacaaacatc ctcatgtatc aaatcggaga cgcaccgaaa aacatcgatg
    25981 ttcttttgga aaatgccaat aagattatcg aaaaagaagc aggggcccat ctagacatca
    26041 agtatatctc atggggggac tataaagata aaatggccat tattacctca tctggtgagg
    26101 aatatgatat tgcctttgca gacaactata ttatcaatgc gcaaaaagga gcttatgctg
    26161 atttaacaga actttacaag aaagaaggca aggccctcta tgacattatt gaccctgcct
    26221 atatcaaagg aaataccatc gacggaaaaa tctacgcagt ccctgtcatc ggtaacgtag
    26281 ctagtcaaca gatgctttcc ttcaaccaag acatggttga taagtatggt tttgacattt
    26341 ctaaagtaga tagctacgat gatgtggaaa gcatgttggc aaccatcaaa gaaaaagaag
    26401 cagatgtaac accatttgcc tgggtaaaat ctagcaaacc ctcaacagac ggcttggaat
    26461 atccagctgg gaatgagtta ccatttgcta tcgacttgaa aggcgacact acaaaagtgg
    26521 taaacccatt tgaagtggac cgtcacatgg ataaccttcg taccattcac aaatactata
    26581 aggctggcta cattatggca gatgcagcga ctactgacgc aaccttctca cttgatgtag
    26641 caaactggtt cgttcgtgaa gaaacacaag gaccagctga ctttggcgat agcctccttt
    26701 caacagttgc aggctataag attacttcta aaccaatcac atctgcctat aagacaagcg
    26761 gatctaccca agtagcaaac tttgtcattt caaaaacatc taagaacaaa gaaaaagcta
    26821 tggaagtatt gacccttatc aatacaaatc cagaattgct gaacggcttg gtatttggtc
    26881 cagagggagt caactgggaa aaagacccaa gtgctgaaaa tcgtatcaag ttgttggatg
    26941 gttacaaagg cgatactcgt atgtcagctt ggaacacagg taacagccaa attctctaca
    27001 tcactgacaa ggtaacagat gaagatgtga aaaaagcaga agaattgctg gcaggtgcag
    27061 aagagtctcc acttcttggc ttcaacttca atgctgatgc agttaagact gaaattacaa
    27121 gtatccaaaa tatcatgagc caatatgcag caagtatcaa tactggtact gtggatcctg
    27181 atgttgctgt tccagaaatg ctgaaaaaat tggaagcaga agaatcctac aaaaaagtaa
    27241 aagaagaaat gcaaaaacaa tacgatgagt ttttagcaaa taaataatac gatacaggtg
    27301 atgaagtgtg aaaagaggga gtgggaaaga actcgactgg tctaaaaaaa gttcgtcaac
    27361 aatttttcgt tttaagttgt tgagctgaaa cagtctatcc ccatactgtt tcactcccac
    27421 ccccgcacag ctcaaactgt ctgggagaca gtttgaggtt ggagatgaag cgaattctgt
    27481 tcgcatcagt cgtataggtc ggatttggag tgtaaaacac gaacaaatct gccaatcaac
    27541 cactgcgatg agatgtcgac acgaact
//
LOCUS       DBNFCO010000022        26873 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.022, whole genome shotgun sequence.
ACCESSION   DBNFCO010000022 DBNFCO010000000
VERSION     DBNFCO010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 26873)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26873)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26873
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.022"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(<1..285)
                     /locus_tag="AC1PIV_000775"
     CDS             complement(<1..285)
                     /locus_tag="AC1PIV_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HIP6611812.1"
                     /translation="MRVVFGIDVSKASSEVAILVNGEKVHNYTMSNDAIGFSRLLGDL
                     KTVHKPEIIFEATGVYSRRLQAFLDEHGYAYTRLNPLEAKKQLDSLRVRKT"
     gene            619..984
                     /locus_tag="AC1PIV_000776"
     CDS             619..984
                     /locus_tag="AC1PIV_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HIP6611813.1"
                     /translation="MTVKINTKDGQIELTDDVIATVVGGATTEIFGVVGMASKSAIKD
                     NFQALLRKENYSKGVVIKTLEDGRIAVDVYTVMSYGVKISEVSRNIQERVKFNLENQL
                     GISVDAVNVFIQNIKVVGE"
     gene            987..2651
                     /locus_tag="AC1PIV_000777"
     CDS             987..2651
                     /locus_tag="AC1PIV_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004193336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HIP6611814.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTITNGAKEVADKSASTVGEVAQILSKGLLMGARGNSGVITSQLFRGFGQSVKGKVE
                     LDGKDLAQAFQHGVEVAYKAVMKPVEGTILTVSRGAATAALKKAEETDDAVEVMRATL
                     DGANRALKKTPEMLPVLKEVGVVDSGGQGLVYIYEGFLSALTGEYIASEDFEATPAVM
                     SEMINAEHHKSVAGHVATEDITFGYCTEIMVALRQGPTYVKDFDYEEFRNYLNDLGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQAGLQYGSLVKVKVDNMREQHEAQVEKVESFQKPA
                     EQKEYAIIAVAAGEGLTEIFKSQGVDYVISGGQTMNPSTEDFVNAIELVNARNVILLP
                     NNKNILMAAQTAAEVAEVAVKVVETKTLPQGFTSLLAFDPSRDLESNFEAMTASLAEV
                     KSGSVTTAVRDTTIDGLEIHENDNLGMVDGKIVVSNPDMMETLVATFDKMLDEDSEIV
                     TIYIGEDGNEELAQTLAEQLEEQFEDVEVEIHQGNQPVYPYLFSVE"
     gene            2752..3192
                     /gene="tsaE"
                     /locus_tag="AC1PIV_000778"
     CDS             2752..3192
                     /gene="tsaE"
                     /locus_tag="AC1PIV_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HIP6611815.1"
                     /translation="MYSQNENELIAIGERIGKACKPNQVLVLSGDLGAGKTTLTKGLA
                     KGLKIEQMIKSPTYTIVREYEGAMPLYHLDVYRIGDDPDSIDLDDFLYGGGLTVIEWG
                     ELLDVSLFDDYLLIRIEKEGDGRRLTVESHGAQSSDLAKEFQNV"
     gene            3185..3712
                     /locus_tag="AC1PIV_000779"
     CDS             3185..3712
                     /locus_tag="AC1PIV_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HIP6611816.1"
                     /translation="MSEKEVYFSEAEPADAAAFIDFMNQVARETDYLVMDETGFRFSV
                     DEIETIFDAGIENPRELCLLAKVGSEVVGAISVKSSKQFRISHIGNIFIAVKKAYWGH
                     GIGTILLEEVLHWAEEMDVLKRLELTVQVRNQAAVHLYQKLGFNIEGTQIGGARTDEG
                     EWLDLYYMGKLIGEV"
     gene            3709..4902
                     /locus_tag="AC1PIV_000780"
     CDS             3709..4902
                     /locus_tag="AC1PIV_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HIP6611817.1"
                     /translation="MTIGKKIFLMSLAIIGLTVGAGLIYGASLLNFSTDAISKTFKQL
                     DGEEKITPIDATEPLTILLMGVDMDQATRGGDWEGGRSDSMILVTVNPKTKETNMMSL
                     TRDIMVEIAEANGESSGTVEKLNHSYSYGQAPMAIATIEKMMDINIDRYIEINMDGLV
                     ELVDAVGGIEVNNTLGFPISISEHEPAYTSIVQPGKQLVNGDQALVYARMRYDDPEGD
                     IGRQRRQREVITAIIKKLLQLDGFTQYKKILTAISNNMRTNIEISPVTIPNLLGYKDS
                     VSKLNSYQLRGVDQMVDAIYYQLPTSTHLLEMQNVLKKSIGLEEKTDLVTNVKVYEGQ
                     MGLPSPINVYDAYTNLLLLEASPWAESLDPEIGSPSATTTVTTEEQVTDFSTEPVLGD
                     ENGAQ"
     gene            complement(5011..5313)
                     /locus_tag="AC1PIV_000781"
     CDS             complement(5011..5313)
                     /locus_tag="AC1PIV_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein"
                     /protein_id="HIP6611818.1"
                     /translation="MKLRNIILAVSAATASFLAVTHRDKITKEIKETKQLLSDIQLSK
                     DNIQEQLAIIQSFQEPLQEMASDLQYKTRVYQQSIAGNLEEIQQILKKYQNENNTP"
     gene            complement(5315..5728)
                     /locus_tag="AC1PIV_000782"
     CDS             complement(5315..5728)
                     /locus_tag="AC1PIV_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HIP6611819.1"
                     /translation="MSDCIFCKIISGEIPASKVYEDDQVLAFLDITQVTKGHTLVVPK
                     KHYRNVLDMDEEAAATLFSVVPTIARQLKEKLRASGLNIVNNNEEAAGQTVFHTHIHL
                     LPRFNNQDGLSIQFKANAPDFPALAQLAQELYLGE"
     gene            5791..6525
                     /locus_tag="AC1PIV_000783"
     CDS             5791..6525
                     /locus_tag="AC1PIV_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIP6611820.1"
                     /translation="MLEVKNVTGGYVNIPVLKDVSFTVEDGQLVGLIGLNGAGKSTTI
                     KEIIGLLTPYQGQIVIDGLTLLQGAENYRKKIGFIPETPSLYEELTLKEHLEVVAMAY
                     DLSWEQAWGRVEHLLKLFRLDEKLDWFPVNFSKGMKQKVMIICAFMVEPSLLIVDEPF
                     LGLDPVAISDLIALLGEEKSKGTSILMSTHVLDSAEKMCDSFVILHQGQVRATGNLEE
                     LQSAFGMDGASLNEIYLALTQEGVAG"
     gene            6522..7562
                     /locus_tag="AC1PIV_000784"
     CDS             6522..7562
                     /locus_tag="AC1PIV_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIP6611821.1"
                     /translation="MKELFQQRRLDFLNRCSKYLRYVLNDHFVLVLMVLLGFLSLQYR
                     QLLLSFPENPLPIVLVVIAISLLVLLSGRIATYLEEADQIFLLTKEKDILQGLEVAAR
                     RTVLFWSSIQVVVQLVLLPIYLKLGLPVWMIVSGLLTLLVLKCLFVKRQLVAYQSQGV
                     LDWSKAIQDEQKRKQSILRFFALFTTVKGIGTTVKPRSYLNGILRLVKSRQTWFYLYL
                     RAFLRSGDYLGLTIRLLLLAILSLFAIEESWLSIGLVLVFHYLLVFQLLGLYKHYDYQ
                     YITQLYPLEKDSKKIGLQNLLRVILYSLLVVELGFALLFSKENAMVVVLLLVGIFLHE
                     IYLPLKLKKLID"
     gene            7612..8406
                     /gene="ccrZ"
                     /locus_tag="AC1PIV_000785"
     CDS             7612..8406
                     /gene="ccrZ"
                     /locus_tag="AC1PIV_000785"
                     /EC_number="2.7.1.15"
                     /EC_number="2.7.1.229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004747 - ribokinase activity [Evidence
                     IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0051726 - regulation of cell cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell cycle regulator CcrZ"
                     /protein_id="HIP6611822.1"
                     /translation="MQFDTSGLQLQSIAGNSGKAFKGLRSDGTPVFVKYEMPPIVSAL
                     AREQITPPVLSANREVGMGHRVEQEWLNGRTLERQDMTSKQIRQILVRMHYSRILLNQ
                     ALQMNYTYMEPQDLVYRWQKEAPTRLGQNSYLQSICQDLLNNLPRFRQEVATFVHGDL
                     HHSNWVETTSGLVYLTDWETACVTDRMLDVAYILTHYIPRQSWEEWLRAYGYKYNSTV
                     LNKVYWYGQLGYLNQIAKHVESYNVLAANKEIYALRQFRQSFYKEV"
     gene            8403..9041
                     /gene="trmB"
                     /locus_tag="AC1PIV_000786"
     CDS             8403..9041
                     /gene="trmB"
                     /locus_tag="AC1PIV_000786"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HIP6611823.1"
                     /translation="MRVRNRKGASELLANNPQYVISNPEECKGKWAEIFGNNNPIHIE
                     VGSGKGRFVTGMAAQNPDINYIGIDIQMTVLSYALDRVLEAGLPNIKLLQVDGSSLTN
                     YFAPAEIDQLYLNFSDPWPKKRHEKRRLTYKSFLDTYKEILPEKGEIHFKTDNRGLFE
                     YSLASFSQYGMVLKQVWLDLHADGLEGNVMTEYEEKFSNKGQVIYRVEAQFQ"
     gene            9612..10082
                     /gene="rimP"
                     /locus_tag="AC1PIV_000787"
     CDS             9612..10082
                     /gene="rimP"
                     /locus_tag="AC1PIV_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HIP6611824.1"
                     /translation="MSSIIELVTAAITPAIQTPYELVDVEYGKMGGDYVLSIFVDKEG
                     GISLQDTADLSEKISPILDTIKPDPFPDQYMLEVTSPGLERPLKTADAVEKAVGKYIH
                     VKLYQAIDKIKVFEGTLLSFDGTDLIMEYMDKTRKKEVTIPYQTVAKARLAVKL"
     gene            10156..11298
                     /gene="nusA"
                     /locus_tag="AC1PIV_000788"
     CDS             10156..11298
                     /gene="nusA"
                     /locus_tag="AC1PIV_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HIP6611825.1"
                     /translation="MSKEMLEAFRILEEDMGINKADIIDAVTESLRSAYKRRYGQSES
                     AVIEFDEKKGDFHVFTVREVVDEVFDSRLEISLKDALAISSAYEMGDKIKFQEDPAEF
                     GRVAAQSAKQTIMEKMRKQKRAITFNTYKQHENEIMSGTVERFDNRFIYVNLGTIEAQ
                     LSKQDQIPGEVFQSHDRIEVYVYKVEDNGRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGSNIKKITSKFHPARYDAKNDR
                     MIPTEENIDVIEWVADEAEFIYNALAPAEVDQVLFDTEDGKHATVVVPDDKLSLAIGR
                     RGQNVRLAAHLTGFRIDIKSASEYEAFEATQYATDEVVEEVAEEQE"
     gene            11315..11611
                     /gene="rnpM"
                     /locus_tag="AC1PIV_000789"
                     /gene_synonym="ylxR"
     CDS             11315..11611
                     /gene="rnpM"
                     /locus_tag="AC1PIV_000789"
                     /gene_synonym="ylxR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase P modulator RnpM"
                     /protein_id="HIP6611826.1"
                     /translation="MAKARKIPLRKSVVSGEIIDKRDLLRIVKNKEGQVFIDPTGKAN
                     GRGAYIKLDNDEASQAKKRRVFDRSFSMEVAEEFYDELIAYVDHKIKRRELGLE"
     gene            11568..11906
                     /locus_tag="AC1PIV_000790"
     CDS             11568..11906
                     /locus_tag="AC1PIV_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HIP6611827.1"
                     /translation="MLIIRSRGENLDSNKRQQILNLLGLAQRAGRLVSGEDLVVEAIQ
                     KGQAKLVFLAEDAAGNLSKKVTDKSHTYQVEVVTVFSTLELSAAVGKARKVLAVTDAG
                     FTKKMRSIME"
     gene            11924..14746
                     /gene="infB"
                     /locus_tag="AC1PIV_000791"
     CDS             11924..14746
                     /gene="infB"
                     /locus_tag="AC1PIV_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HIP6611828.1"
                     /translation="MSKKRLNEIARELGVSSKEVVAKAQELGFEVKSHASSVDEASAK
                     RLAESFGGQKSEATKVAAKVSKPEKVDETPKVETAKVEKAKETQPVVKEEVAASAVQS
                     ASHRPQSRNFKAEREARAKEQAAKRAQNQGKGGQAKSDQDRRDNRQLGQGRSNNERND
                     RRDNRRDQRPEERKDNRFGDRRDNRDNRRQDNRSGRLARFEQREAAKPAGPKIDFKAR
                     AAALKAEQNAEYARTSEERFRQAQEAKKQPKKPKEIKFEEPVVESKPFVKPALVASVP
                     EQVAETTVDTRRKKQARPDKKRDFNSDEEDGPRKQQRNRNSQNQVRNQRTSNWNNNKK
                     NKKGKANQPAKPVTERKFHELPTEFEYTAGMTVAEIAKRIKREPAEIVKKLFLMGVMA
                     TQNQSLDGDTIELLMVDYGIEAKEKVEVDNADIERFFVEEGYLNEEEMTERPPVVTIM
                     GHVDHGKTTLLDTLRNSRVATGEAGGITQHIGAYQIEEAGKKITFLDTPGHAAFTSMR
                     ARGASVTDLTILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGE
                     LAEHGVISTAWGGESEFVEISAKFNQNIDELLETVLLVAEIQELKADPTVRAIGTVIE
                     AHLDKGKGAVATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKTAGPSTPVSIT
                     GLNETPMAGDHFAVYEDEKSARAAGEERAKRALLKQRQATQRVSLENLFDTLKAGEVK
                     SVNVIIKADVQGSVEALASSLQKIEVEGVRVNIVHSAVGAINESDITLAEASNALVIG
                     FNVRPTAEARSQAEADDVEVRLHSIIYKVIEEMEDAMKGMLDPEYEEKIIGEAIIRET
                     FKVSKVGTIGGFMVVRGKVTRDSSVRVIRDGVVVFDGKLASLKRYKDDVKEVGNAQEG
                     GLMIENYNDLKVDDTIEAYIMEEIKK"
     gene            14902..15255
                     /gene="rbfA"
                     /locus_tag="AC1PIV_000792"
     CDS             14902..15255
                     /gene="rbfA"
                     /locus_tag="AC1PIV_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HIP6611829.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMVGD
                     LSTAKVYYTIMSNLASDNQKAQTGLEKATGTIKRELGRKLTLYKIPDLVFEKDQSIEY
                     GNKIDQMLRALDQKD"
     gene            15537..16208
                     /locus_tag="AC1PIV_000793"
     CDS             15537..16208
                     /locus_tag="AC1PIV_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HIP6611830.1"
                     /translation="MKIFISKLMLVSTVVLLAACQSNQVKGGESSSSSASSQVSDGSS
                     LQQASTIASSSETQASSVTTPELSEVYQSVIDRYQANMGQPAEAINQDEASSYLSLLT
                     SQGQEYSGIFYSLYDVNHDGTEELLLALDKSGEYVLIDLYTQLADESLRLVDNFRNLG
                     FEIGPDALLRPLQDGTYLFEGAGVFRIYQYNAMIPGLKRISESDTNPETSPLLELKSL
                     HWVKL"
     gene            16373..17527
                     /locus_tag="AC1PIV_000794"
     CDS             16373..17527
                     /locus_tag="AC1PIV_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate-binding domain-containing protein"
                     /protein_id="HIP6611831.1"
                     /translation="MKTNLKKLLYSGVTLMSLGVLAACSSTSSSTTTSSSAATSQTSV
                     ATTSNNSTSSDSSSSTIDWSALPTTEVKLSNDGLKITEGGTYILTGSTTAGVTVETDA
                     NVRIILAGAEISSSDTAAINVINADNVELEIKDGTTNTVKDTSNHTDTNIEGAIHVEA
                     DLTITGNGSLTVEGNFQDGIVSTDDLVVNSGNITVTAVDDGIRGKDSLTINGGTINVT
                     AGGDGIKSTNDTDTTKGYTTITGGEITVTAGDDGIKAETALTIDGGTITVSESAEALE
                     GTNITINGGTLDVYGSDDAINAASTTSSEIFIKVTGGDLKVAVGSGDTDAFDANGDIY
                     ISGGTIDVTAQSAFDFDGTAELTGGTVTVNGEQITQITATGPGAGGHGGW"
     gene            complement(17563..18222)
                     /locus_tag="AC1PIV_000795"
     CDS             complement(17563..18222)
                     /locus_tag="AC1PIV_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trimeric intracellular cation channel family
                     protein"
                     /protein_id="HIP6611832.1"
                     /translation="MEFDLFLMICNYIGTIAFAVSGAVKGFKKKLDIFGISLLGIITA
                     VGGGIIRDTMANRIPAALTDPTAIYLSLGVAISMYLIVINLKQDKPLDKKMIHFLSQT
                     NLIFDAIGLAIFALIGASTGISLQLNALTSGILAALTGVGGGITRDLLVNETPIVLKE
                     DVYAVLAFFSGVLYHLCVVNWKLPQIPTFITIFTISLIIRLLVIKYKINLPNMESKRK
                     V"
     gene            18455..19423
                     /locus_tag="AC1PIV_000796"
     CDS             18455..19423
                     /locus_tag="AC1PIV_000796"
                     /EC_number="1.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016624 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, disulfide as
                     acceptor [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HIP6611833.1"
                     /translation="MVSITKEQHLDMFLKMQQIRDVDMKLNKLVRRGFVQGMTHFSVG
                     EEAAAVGPIAGLTDEDIIFSHHRGHGHVIAKGIDINGMMAELAGKATGTSKGRGGSMH
                     LANVEKGNFGSNGIVGGGYALAVGAALTQQYLGTDNIVIAFSGDSATNEGSFHESMNL
                     AAVWNLPVIFFITNNRYGISTDISYSTKIPHLYQRAAAYGIPGHYVEDGNDVIAVYEK
                     MQEVIEYVRAGKGPAMVEVESYRWFGHSTADAGVYRTKEEVNEWKAKDPLKKYRKYLT
                     ENKIATDEELDAIEAQVAEQVEASVKFAQESPDPDISVAYEDVFVD"
     gene            19710..20705
                     /locus_tag="AC1PIV_000797"
     CDS             19710..20705
                     /locus_tag="AC1PIV_000797"
                     /EC_number="1.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HIP6611834.1"
                     /translation="MAETKVMALREAINLAQSEEMRKDEKVFLMGEDVGIYGGDFGTS
                     VGMLDEFGPKRVRDTPISEAAIAGSAVGAAQTGLRPIVDLTFMDFITIALDAIVNQAA
                     KTNYMFGGGLKTPVTFRVASGSGIGSAAQHSQSLEAWLTHIPGIKVVAPGTANDAKGL
                     LKSSILDNNPVIFLEPKALYGKKEEVNLDPDFYIPLGKGEIKREGTDVTIISYGRMLE
                     RALKAAEEVAAEGISVEVVDPRTLIPLDKELIIESVKKTGKVILVNDAYKTGGFIGEI
                     ASIITESEAFDYLDAPIIRIASDDVPVPYANILENAVLPNVEKIKAAIYKQVNKG"
     gene            21046..22434
                     /locus_tag="AC1PIV_000798"
     CDS             21046..22434
                     /locus_tag="AC1PIV_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002885106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045254 - pyruvate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006086 - pyruvate decarboxylation to
                     acetyl-CoA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HIP6611835.1"
                     /translation="MAIEIIMPKLGVDMQEGEIIEWKKQEGDFVNEGDVILEMMSDKT
                     SMELEAEESGVLLKIVHGNGATVPVTEVIAYIGAEGETVEAGASSAPAVEPAAAIEEV
                     PAGRTPVIVAPATAAKPQGSGKVRATPAARKLARELGIDLGLVPGTGANGRVHKVDVE
                     DFKGAAPKATPLAARIAADQGVDLSTLTGSGVNGKIVKNDVLAVLAPVAVETAAPVPK
                     AEEKPAKELPEGVEIIKMSPMRKAISKGMVNSYLTAPTFTLNYDIDMTNLMALRKQVL
                     EPIMNKTGLKVTFTDLIGLAVVRTLMKEEHRYMNASLINDAQEIELHKFVNLGIAVGL
                     DDGLVVPVVHGADKMSLSDFVVASKDVIKKAQSGKLKGAEMSGSTFSITNLGMFGTKT
                     FNPIINQPNSAILGVASTVQTPVVIDGEIKIRPIMALCLTIDHRIIDGMNGAKFMVDL
                     KNLLENPLELLI"
     gene            22708..24468
                     /gene="lpdA"
                     /locus_tag="AC1PIV_000799"
     CDS             22708..24468
                     /gene="lpdA"
                     /locus_tag="AC1PIV_000799"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     (NADH) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HIP6611836.1"
                     /translation="MAIEIIMPKLGVDMQEGEIIEWKKQEGDFVNEGDVILEMMSDKT
                     SMELEAEESGVLLKIVHGNGATVPVTEVIAYLGAEGESVEVGAALAPAEVAQATADLK
                     AAGLEVPATPAAAPQAPKAELAADEYDMVVVGGGPAGYYAAIRGAQLGGKIAIVEKSE
                     FGGTCLNKGCIPTKTYLKNAEILDGLKIAAERGINLASTNYTVDMDKTVDFKNKVVKT
                     LTGGVQGLLKANKVTIFNGLGQVNPDKTVVIGDKVIKGRSIILATGSKVSRINIPGID
                     SKLVLTSDDILDLREIPKSLTVMGGGVVGVELGLVYASYGTEVTVVEMADRIIPGMDR
                     EVSVELQKVLSKKGMKFLTSVGVSEIVEANNQLTIKLNDGSEIVSEKALLSIGRVPQL
                     AGLENLNLELDRGRIKVNEYQETSIPGIYAPGDVNGTKMLAHAAYRMGEVAAENAIHG
                     NHHKAKLDFTPAAVYTHPEIAMVGLTEDQAIEKYGKENILIGRNSFTGNGRAIASNEA
                     HGFVKVIADKKYHEILGVHIIGPVAAEMINEAATIMESELTVDDVAASIHGHPTFSEV
                     MYEAFLDVLGVAIHNPPKRK"
     gene            complement(24520..25710)
                     /locus_tag="AC1PIV_000800"
     CDS             complement(24520..25710)
                     /locus_tag="AC1PIV_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6688 domain-containing protein"
                     /protein_id="HIP6611837.1"
                     /translation="MSKHLKSFLIFYLAASIFLPFMWFINAPLICFVLPLYLTWKNIR
                     HFWDLLKKQLKEYSFWINDGLIFFLGTGLSWLALEMAQVVYVDWPETLVNNQIHSPMQ
                     TEAWSGQFFLLLLGVLAYLVLNIFQTKLLPPLLTVLLISCLYPSFVFAVLWTIQLSSL
                     IETDFFTYCYLCLVPFNICLIYSRTILQTIQLWQAELAKQSNPRFPRLSALLQKSLSL
                     PIWLLFFSLPYLAVLGSYLILFGQKPDQLLQMWTETSDWALSEKISPPNAFYDEHYLC
                     TVGAAGHRKLVKPIRMGERHGHRVVVNRQLQIANAFEQILEERCPRLHRCVRSNYDRY
                     GYPISKHIRKAWQADLIYLIMKPAEWLFLIVIYLHDRQPENRIAVQYLPLSKNLLPQE
                     NTSN"
     gene            25840..26829
                     /locus_tag="AC1PIV_000801"
     CDS             25840..26829
                     /locus_tag="AC1PIV_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014677692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HIP6611838.1"
                     /translation="MKYIVNNSNDPAYNIALEAYAFKELTDIDEIFILWINEPAIIIG
                     KHQNAIEEINKEFTDEKGIHVVRRLSGGGAVYHDLNNLNYTIISNKADEGAFDFKTFS
                     KPVIDTLATLGVEANFTGRNDLEIDGKKICGNAQAYAKGRMMHHGCLLFDVDMSVLAS
                     ALKVSKDKIESKGVKSVRARVTNINNELPDKMTVLEFKDAILNQMKQEYPEMDEYVLT
                     EDDLARIQEIRDSQFATWDWTYGQTPEYTVERSVRYPAGKITTYIKAEKSVIESIKIY
                     GDFFGIGDVADVEDLLVGTRYEYADVLAKLQEIDTTHYFSRMTTEEVAKAIVA"
BASE COUNT         8145 a         4945 c         6305 g         7478 t
ORIGIN      
        1 tgttttccgc acacgcaagc tatccagttg cttcttggct tctaagggat tgagtcgtgt
       61 ataagcgtag ccatgttcat ccagaaaagc ttgaagacga cgagaataga cgcctgttgc
      121 ttcaaagatg atttctggct tgtggacggt tttcaaatcg ccaagtagcc gagaaaagcc
      181 aatggcatca ttggacatgg tgtagttatg taccttctcg ccgttgacta gaatggccac
      241 ttctgaactt gccttactca catcaatccc aaaaactact cgcatgatat tacctctttg
      301 tcttgaatga ttccttgttt tagtgatgtc attttcaata ctcgacgtct ggcgtcccac
      361 atactttgat aacattcttt ctaaaacagg tgtcttgcca gtttttgttg cgacgtctag
      421 cgtcaaaaga gttctcgact taacaagaca cctctacttt atcataaaga aaaagtagtg
      481 agtactttct cccgtcggag atttcctcac tactaatctt agtatgtttt tgtaaaatcc
      541 gatgtaacaa gcttgttttt tacagaaagc agaaaatgtg gtaaaatgga gtgataaaac
      601 tatttgaggt aacgaattat gactgttaaa atcaatacta aagacggcca aatcgaattg
      661 actgatgacg tgattgccac agttgttggc ggtgctacga ctgagatttt cggtgttgtt
      721 gggatggcta gtaagtctgc gatcaaggat aattttcaag cacttttgag aaaagaaaat
      781 tattctaaag gtgttgtgat taagaccttg gaagatggtc gcattgcagt cgatgtttat
      841 actgtgatga gctacggtgt aaaaatcagt gaagtatctc gcaacatcca agaacgcgtt
      901 aagttcaact tggaaaatca actaggtatc tctgtagatg ccgtcaatgt ctttatccaa
      961 aatatcaaag tcgtaggaga ataattgtgt ctaaaattac aactagttta tttcaagaaa
     1021 tggtgcaggc agcatcaact cgtctgaata aacaagccga atatgtgaac tcactcaatg
     1081 ttttcccagt tccggatggg gatactggta ccaacatggg gatgactatt accaatggtg
     1141 ctaaagaagt agcagataag tctgcttcta ctgttggaga agttgcgcaa attctttcta
     1201 agggcttgtt gatgggagct cgtggaaact caggtgttat tacgtcgcaa ttgttccgcg
     1261 gttttggtca atctgttaaa ggcaaggttg aattggacgg taaggatttg gcgcaagcct
     1321 ttcaacatgg tgtagaagtg gcttataaag ccgttatgaa gccagttgaa ggaacaattc
     1381 ttactgtttc gcgtggggca gccactgccg ctttgaaaaa ggcagaagag actgatgatg
     1441 cggttgaggt catgcgtgcc actcttgacg gtgctaatcg tgctcttaag aaaacgccag
     1501 agatgcttcc agtcttgaag gaagttggtg ttgtcgattc aggtggacaa ggtcttgttt
     1561 acatttatga aggcttcttg tcagctttga cgggtgagta tattgcttcg gaagattttg
     1621 aggcgacacc tgctgttatg tctgaaatga tcaatgctga gcaccacaag tcagttgcag
     1681 gtcatgtagc gactgaagat attacctttg gttactgtac agaaatcatg gtagctcttc
     1741 gccaggggcc tacttatgtc aaggactttg attatgaaga attccgtaac taccttaacg
     1801 accttgggga ttccctcctt gtggtcaacg atgatgaaat cgttaaagtc catgtccata
     1861 cagaagatcc aggtttggtc atgcaagcgg gtcttcaata tggtagcttg gtcaaggtaa
     1921 aagtggacaa tatgcgtgag caacatgaag ctcaggttga gaaagtagaa agtttccaaa
     1981 aaccggctga acaaaaagag tatgctatta ttgcggtagc tgctggggaa ggtttgacag
     2041 aaatcttcaa atcacaaggc gttgactatg tgatttcagg tggtcagacc atgaacccat
     2101 caacagaaga ttttgtcaat gctattgaat tggtcaatgc ccgcaatgtc atcttgttgc
     2161 caaacaacaa aaatatcttg atggctgctc agacggctgc tgaggttgca gaagttgcgg
     2221 ttaaggttgt ggaaactaag accctaccac aaggttttac tagcttgctt gcttttgatc
     2281 caagtcgtga tttggaaagc aactttgaag cgatgacggc atctctcgca gaggtgaaaa
     2341 gtggtagcgt gacaactgcg gtccgcgata caaccattga cggtcttgaa atccatgaga
     2401 atgacaacct tggtatggtt gatggcaaga ttgtggtttc taatccagat atgatggaga
     2461 cacttgtggc tacctttgat aaaatgttgg atgaagacag cgaaatcgtg actatctaca
     2521 tcggtgaaga tggtaatgaa gaattggctc aaactcttgc tgaacagcta gaagaacaat
     2581 ttgaagatgt tgaggtcgaa atccatcaag gaaatcaacc agtctatcca tatcttttca
     2641 gcgtagaata aacaaaatcg caggctctgg cttgcgattt tttctgtcga cttgtctaca
     2701 atttccagta gacctatgac aaactactgg ggctatggta taattaaaga catgtatagt
     2761 cagaatgaaa atgaattgat tgccattggt gagagaattg gaaaggcctg taagccaaat
     2821 caagttctag tattatcagg ggatttgggt gctgggaaaa caactctgac caagggtttg
     2881 gccaaggggt taaaaattga acagatgatt aagagtccta cttatacgat tgttcgagag
     2941 tatgaggggg ccatgccgct ctatcactta gatgtttatc gaattggaga tgaccctgac
     3001 tcgattgatt tggatgattt tctctatgga ggaggtctaa cggttatcga gtggggagaa
     3061 ttactggatg tcagtctatt tgatgactat ttgctcattc gtatagagaa agagggagat
     3121 ggtcgacgat tgacagtcga atctcatgga gctcaaagta gcgatttagc gaaggagttc
     3181 caaaatgtct gaaaaagaag tgtattttag tgaagctgaa ccagctgatg cagcagcttt
     3241 tattgatttt atgaatcaag ttgctagaga aacggattat ctagtcatgg atgagactgg
     3301 ttttcgattt agtgttgatg aaatagagac catcttcgac gcagggatcg aaaatcctcg
     3361 tgaattgtgc ctgttggcta aggttggttc ggaagtcgtc ggcgcaattt ctgttaagtc
     3421 ctctaagcag tttcgcatta gccatatcgg aaatattttt attgcagtaa aaaaagccta
     3481 ctggggtcac ggtataggga cgattttact ggaggaagta ttgcattggg cagaggaaat
     3541 ggatgtattg aagcgtttgg aattaacggt tcaggttcgc aatcaggcgg cagtacattt
     3601 ataccaaaaa ctaggattca acattgaagg aacccagata ggtggggcta gaacagatga
     3661 aggagaatgg cttgatcttt attatatggg caagttaatt ggtgaagtat gacaattgga
     3721 aaaaaaatat tcttaatgtc tttggctatt attggtttaa cagtaggtgc cggcttaata
     3781 tatggagcca gcttgttaaa tttttctacg gatgctattt cgaaaacatt taagcagcta
     3841 gatggagaag aaaaaataac tccgattgat gcgacagagc ccctaactat cctactgatg
     3901 ggggtggata tggaccaagc gacccgcggg ggagattggg agggtggccg tagtgattcg
     3961 atgattttgg taactgttaa tcccaagact aaggaaacca atatgatgag cttgactcgt
     4021 gatattatgg ttgagattgc agaagcgaat ggggagtctt caggaacggt tgaaaaacta
     4081 aatcattctt atagctacgg acaggcacca atggccattg ccacgatcga aaagatgatg
     4141 gatattaaca ttgaccgtta tatcgaaata aatatggatg gtctggttga gcttgttgat
     4201 gcggttggag gtattgaggt aaacaatact cttggcttcc ctatatccat ttcggaacat
     4261 gagcctgcct acacctctat tgtccagccg gggaaacagt tggtaaatgg ggatcaggcg
     4321 ctggtttatg ctcggatgcg ctatgatgat cctgaggggg atattggtcg tcagagacgt
     4381 caacgtgaag ttataacggc tattataaaa aaactccttc agttagacgg ttttacccag
     4441 tataagaaga ttctgactgc catttctaat aatatgcgaa ccaacattga gattagtcct
     4501 gtaacaattc caaatctctt ggggtacaag gactctgtct ccaagttgaa ttcctatcag
     4561 ttgcgcggtg tggatcaaat ggttgatgca atctattatc aattaccaac cagtacacat
     4621 ctattggaaa tgcaaaatgt tctgaaaaaa tctatcggct tagaagaaaa gaccgactta
     4681 gtcacaaacg tgaaggtcta cgaaggacag atgggattgc caagtccaat aaacgtttat
     4741 gatgcatata caaatctctt gctgttagaa gcaagtccat gggcagaaag cttggatcca
     4801 gaaataggga gtccatcggc tactacgact gtgacaacag aagagcaggt aaccgatttt
     4861 tcaacagagc cagtactcgg tgatgaaaac ggggcacaat aatgtagtca ttagtttttc
     4921 ttttattact ttgacgagcg agtactaaaa gcctataaaa atagaggttg ttttcaacct
     4981 ctatttttat atatttggaa attccagatg ttagggagtg ttattctcat tctggtattt
     5041 tttgagaatc tgttggattt cttccaagtt tcctgcaata ctttgctgat agactcgagt
     5101 cttatattgt aagtcagaag ccatttcctg caagggctct tgaaaacttt ggataatggc
     5161 aagttgttcc tgaatattgt ccttgctcag ttgaatatct gatagaagtt gtttggtttc
     5221 ctttatttct ttggtaattt tatcccgatg cgtgactgca aggaagctgg cggtagcggc
     5281 gcttacggct aaaatgatat tacgaagttt catattattc tcctagatag agctcttgtg
     5341 ccagttgagc cagggctggg aagtcagggg cgttggcttt aaattgaatg ctcaatccat
     5401 cttgattgtt aaagcgtggt aagagatgga tgtgtgtatg aaagacggtt tgcccagcgg
     5461 cctcctcgtt attattaacg atgtttagac cgctagctct aagtttttct tttaactgac
     5521 gagcgatggt tggcacaaca gaaaagagtg tggctgcagc ttcttcatcc atgtcaagca
     5581 cgtttcggta gtgtttttta gggacaacca atgtgtgtcc ttttgtgacc tgagtgatgt
     5641 ctaaaaaggc taatacttgg tcatcttcgt agacttttga agctggtatt tctccagaaa
     5701 taattttgca aaaaatacaa tccgacataa tggcaacctc tttctaggat ttttgttata
     5761 ataattatat caaattatag gaagaaatgt atgttagaag taaaaaatgt aactggagga
     5821 tatgtcaata tcccagtttt gaaagatgta tcttttaccg ttgaggatgg tcaattagtt
     5881 ggtctaattg gtttaaatgg tgcagggaaa tcaacgacta ttaaggaaat tatcggtctt
     5941 ttgacaccct atcaaggaca gattgtaatt gacggcctaa ctttgctaca aggggctgaa
     6001 aattatcgga agaaaattgg gtttatccct gaaacaccaa gtttgtatga agaactaacc
     6061 ctcaaagagc acttggaagt ggtagcaatg gcctatgatt tatcctggga gcaagcttgg
     6121 ggacgtgttg agcacttgtt aaaactgttt cgcttggatg agaaattgga ctggtttcct
     6181 gtcaattttt caaagggaat gaagcagaag gtcatgatta tttgtgcttt tatggtggag
     6241 ccgagtctgt tgattgttga tgagcctttt ctgggattag accctgtggc tatctctgat
     6301 ttaatcgctc ttttggggga agaaaaatct aagggcactt caatcctcat gtccactcac
     6361 gttcttgact cagctgagaa aatgtgcgac tcttttgtga ttttacatca gggacaggtc
     6421 cgtgcaactg gaaatttgga ggagctacaa agcgcatttg gtatggatgg tgcaagtctg
     6481 aatgaaattt atctggcctt gacgcaagaa ggagtggctg gatgaaagaa ttgtttcaac
     6541 aacgccgact agatttttta aatcgttgtt ccaagtatct gcgctatgtt ctgaatgacc
     6601 attttgtttt ggttctcatg gttttattag gctttttgag tttgcaatat cgtcaattat
     6661 tgttgtcatt ccctgagaat ccgttgccga ttgttttggt ggttattgca atcagtctac
     6721 tggtgctatt gtccggaaga attgcgactt atttagaaga agctgatcaa atcttcctat
     6781 tgaccaagga aaaagacatt ctgcaaggac tcgaggttgc agccagacgc acggtcttgt
     6841 tttggtcctc tatacaggtg gtggttcagc ttgttttgtt accaatctat ttgaaactgg
     6901 gtttaccggt gtggatgatt gtatctggtc ttcttacttt gttggtttta aaatgtcttt
     6961 ttgtcaagcg ccaattagtg gcttatcagt cacagggagt attggactgg tctaaggcta
     7021 ttcaagatga acaaaaaagg aaacagtcta ttttacgttt ctttgcctta tttacaacgg
     7081 ttaaaggaat cggtacgact gttaaaccga gaagctatct caatggaatc ttgcgtctcg
     7141 tcaagtcgag acagacttgg ttttatctct acttacgggc tttcttgcgt tcaggagact
     7201 acttgggctt gacgatacgt ctactgttgt tggcgatttt gtccctattt gccattgaag
     7261 aatcgtggtt atccatcggc ctagttttag tctttcatta tttgcttgtc ttccagttgt
     7321 tggggcttta caagcattat gattatcaat atataacaca actgtatcct ctggagaaag
     7381 attccaagaa aattggtctt cagaatttgc ttagagtgat tttatatagt ctattagtag
     7441 tggaattggg ctttgctctg ctattttcta aagagaatgc gatggtagtc gtcttacttc
     7501 tcgtggggat tttcttgcat gaaatatatt tgcctctaaa attaaaaaaa ttgattgact
     7561 aaatagacga aaattagtaa aatagtaagg aatttttaaa ggaggaaagg catgcagttt
     7621 gataccagtg ggctacaatt acagtctatt gcaggaaata gtggcaaagc gtttaaaggc
     7681 ctacggtcag acggaacgcc agtctttgtg aagtatgaga tgcctccgat agtgtctgct
     7741 cttgcgcgtg agcaaattac accacccgtt ttgtcagcaa atcgtgaagt aggaatgggg
     7801 catcgtgtag agcaggagtg gttgaatggt cgtaccttgg agcgtcaaga tatgactagt
     7861 aaacagattc gtcaaatact ggtgagaatg cactattctc gcattttgct caatcaggct
     7921 ttgcagatga attataccta tatggaacct caggatttgg tttatcgttg gcaaaaagag
     7981 gcaccaacta gattgggaca gaattcttat ctgcaatcta tctgtcaaga tttattgaat
     8041 aatctaccaa gattccgtca agaggtggca acatttgttc atggagattt gcatcatagt
     8101 aactgggtag aaacgacgtc tggtttggtg tatttgacag attgggagac cgcttgtgta
     8161 acggatcgga tgttggatgt tgcctatatt ttgacgcatt atattcctcg tcagtcctgg
     8221 gaagagtggc ttcgggctta tggctacaaa tataacagca cagtattaaa taaggtttat
     8281 tggtatggcc agcttggcta tctaaaccaa atagctaagc atgtagaaag ctacaatgtt
     8341 ttggctgcaa ataaagaaat ttatgctcta cggcaattcc gtcagagttt ctataaggaa
     8401 gtatgagagt tagaaatcgt aagggagcga gtgagcttct agcaaacaat ccccagtatg
     8461 ttatctccaa tccagaggag tgtaagggga aatgggcaga gatttttgga aacaataatc
     8521 ctatccacat agaagttggt tctggtaaag gtcgctttgt cactggtatg gctgcgcaaa
     8581 atccagatat taactatatt ggtattgata ttcagatgac cgtgttaagc tatgccttgg
     8641 accgtgtgct tgaagctggt ttaccaaata taaaattatt gcaggtggat ggttcgagtt
     8701 tgaccaacta ttttgcaccg gcagaaatag atcagcttta tctgaatttt tcagatccat
     8761 ggcctaagaa acgtcatgag aaacgccgtt tgacctacaa gtcattcttg gatacctaca
     8821 aggaaatcct acctgagaag ggagaaatcc acttcaaaac agataatcgt ggtctgtttg
     8881 agtatagcct ggctagtttt tctcaatatg gcatggtctt gaagcaggtt tggctagatt
     8941 tgcatgcgga tggtttggaa ggtaacgtta tgacagagta tgaggagaaa ttctcaaaca
     9001 agggtcaagt catctatcgt gtggaagcac agtttcaata attcccttag tggaaaatga
     9061 ggagaggtct aacagagacc tttttccttt gtcgaataaa ctatagtcat tcagtttttc
     9121 ttttattact tcgacgtaag aggaaattcc gtttccttat ttctaagttc aaacactcca
     9181 ctggattgtt tgaattcgct ttgccgtact cttcaggggt gacttgctcc gcaagggcta
     9241 tctccaacct tgcacagtca ctcgactgta caagctgtct gcagctattg aagtgaactt
     9301 gcttcgccct atctccaacc tccaaaggtt ccccaaacct ttggagagag tactaaaagt
     9361 aaactaaaag attataaatg tctataatcc atcgttttcc tttacaaata gggatagata
     9421 tgatagaata atggaagtga ataatgagaa aaggggttgg cgtcagtcaa ccctttccct
     9481 gtacacggat ttctgtatat agaatgaatg atagtacaag ggagtttact gtcaaaggaa
     9541 atagagagtc ctggatagtg cgaactattt gagtaatgta tttctagcga ctgtaaaaat
     9601 aggaggtgtt tatgtcatca attattgaat tggtcacagc agcaattacc cccgctattc
     9661 aaactcctta cgagttggta gatgtggaat atggtaaaat gggcggtgac tatgtcctat
     9721 cgatttttgt cgataaggag ggtggaattt cccttcaaga tacggcagat ttatccgaaa
     9781 agatcagtcc gattttggac actatcaaac cagacccatt tccagaccaa tacatgctgg
     9841 aggtaacaag tccaggtttg gaacgtcctt taaaaacggc agatgctgtt gagaaggcgg
     9901 ttggaaagta catccatgtc aaactctatc aggcaattga taaaatcaag gtttttgaag
     9961 gaacgttgct ctcctttgat ggaacagacc tgattatgga gtatatggat aaaactcgta
    10021 agaaggaagt aactattcct taccagacgg tggctaaggc ccgtttggct gttaagttat
    10081 aatgctcttt catgagtatt ttataaagat attagacttt aagaaaggac cttttgagcg
    10141 caaaaggaaa acaacatgag taaagaaatg ctagaagcct tccgtatttt agaggaagac
    10201 atgggtatta acaaagcgga tatcattgat gcagttacag agtcgcttcg ttcagcttat
    10261 aaacgccgtt atggtcaatc agaatcagca gtgattgaat ttgacgagaa aaaaggcgat
    10321 ttccatgtat ttactgttcg tgaagtagta gatgaagtat ttgatagccg actagaaatt
    10381 agtctaaaag atgccttggc tatttcatca gcttatgaaa tgggtgacaa aattaaattc
    10441 caagaagacc cagcggaatt tggacgtgta gctgctcaat cagctaaaca gaccatcatg
    10501 gaaaagatgc gcaaacaaaa gcgtgccatt accttcaata cctacaagca acatgaaaat
    10561 gagattatgt caggtacggt agagcgtttt gataatcgct ttatctatgt caaccttggt
    10621 acgattgaag cacaattgtc aaaacaagac caaattcctg gtgaggtttt ccaatctcat
    10681 gatcgcatcg aagtctatgt ctacaaggta gaagacaatg gtcgtggtgt taacgtattt
    10741 gtcagccgta gccatccaga aatgatcaaa cgtctcatgg aacaggaaat tccagaagta
    10801 tacgatggaa cagttgaaat catgagtgtt gcccgtgaag ctggagaccg tacgaaagtg
    10861 gctgttcgta gccataatcc aaacgtagat gctattggta ctatcgttgg tcgtggtggt
    10921 tcaaatatta agaaaatcac tagcaaattc cacccagctc gttatgatgc taagaatgac
    10981 cgtatgattc ctactgagga aaatattgac gttatcgagt gggtagcaga tgaagcggaa
    11041 tttatctaca atgcccttgc acctgctgaa gttgaccaag tattgtttga cacggaagat
    11101 gggaaacatg ctacagtcgt tgtaccagat gataagttgt cattggcaat tggtcgtcgt
    11161 ggtcaaaacg ttcgtttggc agcgcatttg acaggattcc gtatcgacat caagtcagca
    11221 tcggagtatg aagcttttga agcaactcaa tatgcaacag acgaagttgt agaagaagtc
    11281 gcagaagaac aagaataagg caaaaggagc aaccatggca aaagctagaa aaataccctt
    11341 gcgcaagtct gtggtgtccg gtgaaatcat cgacaaacgg gatttgctcc gtattgtaaa
    11401 aaataaagaa ggtcaagtat ttatcgatcc aacaggcaag gcaaatggtc gtggagctta
    11461 catcaagctt gacaatgatg aggcaagcca agctaagaaa cgtcgtgtct tcgatcgttc
    11521 ctttagtatg gaagtggccg aagaatttta cgatgaatta attgcctatg ttgatcataa
    11581 gatcaagagg agagaacttg gactcgaata agagacagca aatcttaaat ttattaggtt
    11641 tggcccagcg agctggtcgc ctggtttcgg gtgaggacct ggttgttgaa gctattcaaa
    11701 aagggcaggc aaagttggtg tttttagccg aagatgctgc tggaaattta agtaaaaaag
    11761 taacagataa aagtcatacc tatcaagtag aagttgtaac agtgttttca acactggaat
    11821 tgagtgcagc tgtcggcaag gctagaaaag ttcttgcagt gacagacgct ggatttacaa
    11881 agaagatgag gtctattatg gaatagaaca ggaggacaag gcattgtcta agaagagatt
    11941 gaatgaaata gcccgtgaat taggcgtaag cagtaaggaa gttgttgcta aggctcaaga
    12001 attgggtttt gaagtcaaaa gtcatgcttc aagcgtagat gaagcaagtg ctaaacgcct
    12061 tgcagaaagc tttgggggac aaaaatcaga ggcaactaaa gttgcggcaa aagttagcaa
    12121 gcctgagaag gttgatgaaa ctccaaaagt ggaaacagct aaggtagaaa aagctaagga
    12181 aacacagcca gtagtaaaag aagaagttgc ggcaagtgca gtacaatcag cttcacatcg
    12241 tccacagagt cgaaacttta aggcagagcg tgaagcacgg gccaaagagc aggctgctaa
    12301 gcgagctcag aatcaaggaa aaggtggtca agctaaatct gatcaggacc gtcgtgacaa
    12361 ccgtcaacta ggtcagggac gttcaaacaa tgagcgaaat gatcgccgcg acaatcgtcg
    12421 tgaccagcgt ccagaagagc ggaaagacaa ccgatttgga gaccgtcgcg ataatcgaga
    12481 caaccgtcgt caggacaatc gttcaggtcg gttagctcgc tttgaacaaa gagaggctgc
    12541 aaaaccagca ggacctaaaa ttgacttcaa agcgcgtgct gctgctttga aagcagaaca
    12601 aaatgcggag tatgctcgta ccagtgaaga acgttttcgt caggctcagg aagctaaaaa
    12661 gcaacctaag aagccaaaag aaattaagtt tgaagaaccg gttgtggaaa gcaaaccatt
    12721 tgtgaaacct gcacttgttg catcggtacc agagcaagtt gcagaaacta ctgtagatac
    12781 ccgtcgtaag aaacaagctc gaccagataa aaaacgtgac tttaatagtg acgaagaaga
    12841 tggtccacgg aaacaacaaa gaaatcgaaa tagtcaaaat caagtgagaa atcaaagaac
    12901 aagtaactgg aataacaaca agaaaaataa aaaaggcaag gctaaccaac ctgccaaacc
    12961 tgtcacagaa cgcaagttcc acgaattgcc aactgaattt gaatatactg ctggcatgac
    13021 cgtcgcagaa attgcaaaac gaatcaaacg tgaacctgct gaaattgtga aaaaactctt
    13081 ccttatggga gttatggcga ctcaaaacca atctttggat ggagatacta tcgaactcct
    13141 catggttgat tatggtattg aagcgaaaga aaaggtagag gtcgataacg cagatattga
    13201 gcgtttcttc gtagaagagg gctacctcaa tgaagaagag atgacagaac gcccacctgt
    13261 tgtgactatc atgggacacg ttgaccatgg taaaacaacc ttgttggaca ccctacgtaa
    13321 ttctcgtgtt gctactggag aagctggagg tatcacacag catatcggtg cctaccaaat
    13381 tgaggaagct ggtaagaaaa ttaccttctt ggatactcca ggacacgcgg cctttacttc
    13441 tatgcgtgca cgtggtgcat ctgttaccga cttgaccatc ctagttgttg cagcagatga
    13501 tggtgtcatg ccgcaaacga ttgaggctat caaccactca aaagcagcta atgtgccgat
    13561 cattgtagct atcaacaaga ttgacaagcc aggtgcaaac ccagagcgtg tcatcggtga
    13621 attggctgag cacggtgtta tctcaaccgc ttggggtgga gaatctgaat ttgtagaaat
    13681 ctcagctaag tttaaccaaa acattgatga attgttggaa actgttcttt tggttgctga
    13741 aatccaagaa ctgaaggcag acccaactgt tcgtgcgatt ggtacagtta tcgaagctca
    13801 tttggataaa gggaaaggtg cggttgcaac cctcctcgtt caacaaggga cacttaatgt
    13861 tcaagaccca atcgttgtcg gaaatacctt cggacgtgtt cgtgccatga caaatgacct
    13921 tggtcgtcgt gttaaaactg ctggtccatc tacaccggta tctattactg gtttgaacga
    13981 aacgccaatg gctggcgacc atttcgcggt ttatgaagat gaaaaatcag ctcgtgcagc
    14041 aggtgaagaa cgtgctaaac gtgctcttct taaacagcgt caagcaacgc aacgagttag
    14101 tcttgaaaac ctctttgata cccttaaagc aggtgaggtt aagtcagtta atgtgattat
    14161 caaggccgac gtacaaggtt ctgttgaagc tcttgcatca tcgcttcaaa agattgaagt
    14221 agagggagta cgtgtcaata tcgtccactc tgcagttggt gctatcaatg aatcagatat
    14281 tactcttgcg gaagcttcaa atgctcttgt gattggtttc aacgttcgtc caacagctga
    14341 agcgcgtagc caagctgaag cagatgatgt tgaagtacgt cttcacagca tcatttacaa
    14401 ggttatcgaa gagatggaag atgccatgaa aggtatgctt gatccagaat atgaagaaaa
    14461 aatcattggt gaggcaatca ttcgtgaaac cttcaaggta tccaaagttg gaacaatcgg
    14521 tggtttcatg gtcgtacgtg gtaaggttac ccgtgattca agtgttcgag ttatccgtga
    14581 tggtgttgta gtatttgatg gtaaactagc tagtttgaaa cgctataaag atgacgtgaa
    14641 agaagttggt aatgcccaag agggtggttt gatgattgag aactacaacg acttgaaagt
    14701 tgatgatacc attgaagctt acatcatgga agaaatcaaa aaataatatt ttctcactgt
    14761 caaagtcata gacaagtgat tttgtcgagg aagtgacaat ttaatagatt ttagtaggtt
    14821 ttaaagcaat agtttttaat ctacttggat tattcaagct ggggaaactc agcttttcta
    14881 tcatctaaga aaggaaagaa tatggcgaat cattttcgta cagaccgtgt cgggatggaa
    14941 atcaagcgcg aagtcaatga gattttgcaa aagaaagttc gtgatccacg tgtgcaggga
    15001 gtgactatta cagatgttca gatggtcggc gatttgtcaa cggccaaggt ttattacaca
    15061 atcatgagta atttggcatc cgataatcaa aaagcacaaa cgggtcttga aaaagcaacg
    15121 ggaaccatta agagagaact tggtcgtaag ttaactcttt ataaaattcc ggatttggtc
    15181 tttgaaaaag accaatcaat tgagtacggc aataaaattg accaaatgtt gcgtgctctt
    15241 gatcagaaag attaacaaca aaagtcggat ggcaacattc ggctttttct ggctcggatg
    15301 ctttgtccat atatggtggc gtttacaagc cctcggaaag atgttatact aatactcaat
    15361 gaaaatcaaa agtagactag gaaacgaagt cgaagataga actctgttac tatcttattt
    15421 catggtaaca ggctgaaaac ctccactgga gcttttcact catcaaggca agttgacaac
    15481 ggataatttt gattttcgaa gagtataaga ccaaagatag agcacaggag gaagttatga
    15541 aaatatttat tagtaaactg atgttagtgt ccacggttgt actattagct gcttgtcagt
    15601 ctaatcaggt aaaaggtggt gagagttcta gttctagtgc ttcaagccaa gtttcagatg
    15661 gttctagttt gcagcaagcg tcaacaatag catctagctc cgagacgcaa gcatcctcag
    15721 tgaccactcc tgagctaagt gaagtatacc aatcagttat tgatcgttat caagcgaata
    15781 tgggtcagcc tgctgaggca attaatcagg atgaggccag tagctatctg agcttattaa
    15841 ctagccaggg gcaagaatac agtggaatat tttatagttt gtatgatgtt aaccatgatg
    15901 gtacagagga gctgcttcta gctttggaca agtcgggaga atatgtctta attgaccttt
    15961 atactcagct tgccgatgag agtctacgtt tggtggataa tttccgcaat cttggatttg
    16021 aaattggacc ggacgcccta cttcgtcctt tacaggatgg aacatactta tttgaaggag
    16081 ctggtgtttt tcgcatttat caatacaatg cgatgattcc aggtttaaaa cggatttctg
    16141 aatcagatac caatcctgaa acttctccct tgcttgagtt gaaaagcttg cattgggtta
    16201 agctatagat tttatcaatg attattccta ggctgggttt cccggccttt tgtagttcct
    16261 aagaagttta agttttcttt tggcaatctt taatctttct tttaggaagg aaaggtaaac
    16321 taggagcata tcaggaaggg atacgacttc ctaaagaaaa ggaatctaca ttatgaaaac
    16381 aaatcttaaa aaattacttt actctggtgt tactcttatg agccttggtg tcttagcagc
    16441 atgttcatct acttcaagtt caacgactac ttcaagctca gcagcaacta gtcagacaag
    16501 tgtagcgaca acttcaaata atagcacttc atcagattca agttcgtcaa ctattgactg
    16561 gtcagccctt ccaacgacag aagtgaagct ttcaaatgat ggcttgaaaa ttactgaggg
    16621 tggaacctat attttaactg gttcaacaac agctggtgta acggttgaaa cagatgccaa
    16681 tgttcgcatc attctagcag gtgctgagat ttcaagttca gatacagcag caatcaatgt
    16741 tattaatgct gacaatgttg aattggaaat caaagatggt acgacgaata cagtgaaaga
    16801 taccagcaat catacagaca ccaatattga aggggctatc catgttgaag ctgatttgac
    16861 catcactggt aatggtagcc tgaccgttga aggcaacttc caagatggca tcgtatcgac
    16921 agatgacctt gtcgtgaatt caggaaatat taccgtcact gcagtggatg atggtatccg
    16981 tggtaaggat tcattgacaa tcaatggtgg tacaatcaat gtaacagcag gtggtgatgg
    17041 tatcaagtct acaaatgata cagatactac caaaggttat acaactatca caggtggtga
    17101 aattactgta acagcaggtg atgatggtat taaagcggag acggctttga caattgacgg
    17161 aggtaccatt acagtatcag aatcagcaga agccttggaa ggaactaata tcactatcaa
    17221 tggtggtaca ttagatgtct atggttcaga tgatgctatt aatgcggcaa gtacaacatc
    17281 atcagaaatc ttcatcaagg taactggcgg tgacttgaaa gtagctgtag gtagtggaga
    17341 tacggatgcc tttgatgcta atggagacat ttatatctca ggtggtacaa ttgatgtaac
    17401 agctcaatct gcttttgact tcgacggaac tgctgaattg acaggaggta ctgtgacagt
    17461 taacggtgag cagattactc aaatcacagc aacaggacca ggtgctggtg gccacggtgg
    17521 ctggtaatca ataataatac aaaaaggtct gagttgacga actcagacct ttcgtttgct
    17581 ttccatattg ggaagattga ttttgtattt aattaccaat aatcgaatga ttaaagaaat
    17641 ggtaaaaata gtgatgaagg ttggaatttg tggtaatttc caatttacaa cgcaaagatg
    17701 atagaggact ccagagaaaa atgcaaggac agcatagaca tcttctttaa gaacaatggg
    17761 tgtttcattg acgagtaaat cacgggtgat tccgcctccg acacctgtca aagctgccag
    17821 aataccactg gttagagcgt ttagttggag agagatgcca gtactggctc caatgagggc
    17881 gaagatggct agaccgatcg catcaaagat aaggtttgtc tgggaaagga aatgaatcat
    17941 cttcttatca agtggtttgt cctgctttag attgataaca atcaagtaca tgctaatcgc
    18001 tactccgaga gataaataga tggctgtagg atcagtcaag gcggcaggaa tgcgattggc
    18061 catcgtatct cgaataattc ccccaccaac ggcggtaatg ataccgagca agctaattcc
    18121 aaaaatatct aactttttct taaatccttt tacggccccc gaaacagcaa atgcgatagt
    18181 gcctatgtag ttacaaatca taagaaataa atcgaattcc ataagaacct ccgtacctat
    18241 attaacagaa agaaagacgg cgtgcaagct tatttcaaag tttgtgaaaa aagtttcaaa
    18301 caagtaaagt gaatctttta atgatttgtg aaaaaacgca ctaaatcaag gttttcacaa
    18361 aaatttctgt aaaaagaaaa cggttcaatt acttgccatt tgtgaaatat tggtctatca
    18421 tagtacagaa agagaaaaac ctttggagga aattatggta tctatcacaa aagaacaaca
    18481 tttggacatg ttcttgaaaa tgcaacaaat ccgtgatgtt gacatgaaat taaacaaatt
    18541 agtgcgtcgc ggtttcgtac aaggtatgac tcacttctca gtcggtgaag aagctgcggc
    18601 tgttggacct attgctggat tgacagatga ggacatcatc ttctcacacc accgtggtca
    18661 cggtcacgtt attgcaaaag gtattgacat caacggcatg atggctgagc ttgctggtaa
    18721 ggcaacaggt acatctaaag gtcgtggtgg ttcgatgcac ttggctaacg ttgaaaaagg
    18781 aaactttggt tcaaacggta tcgtaggtgg tggttatgcc cttgcggtgg gtgcggccct
    18841 tacgcaacaa tacctcggta cagataacat tgttattgcc ttctcaggtg attcggctac
    18901 taacgaaggt tccttccacg aatcaatgaa cttggcagct gtttggaact tgccagttat
    18961 cttcttcatt acaaacaacc gttacggtat ttcaactgac atttcttatt ctactaagat
    19021 tcctcacctc taccaacgtg ctgctgcata cggtattcca ggtcattatg ttgaggatgg
    19081 taacgacgtt attgctgttt atgaaaaaat gcaagaagtc atcgagtacg ttcgtgcagg
    19141 taaaggtcca gccatggtcg aagttgaatc ataccgctgg tttggtcact caactgccga
    19201 tgcaggtgtt taccgtacta aagaagaagt caatgagtgg aaagcaaaag acccacttaa
    19261 gaaataccgc aaatacttga cagaaaacaa gattgcgaca gacgaagaat tggatgccat
    19321 cgaagcacaa gtcgcagaac aagtagaagc atctgtgaaa ttcgcacaag aaagcccaga
    19381 tccagacatc tcagtagctt atgaggatgt gtttgtagac tagggtgtga ggacgttaaa
    19441 gaggcacaga aaaattagag agtcagctag tgatgtggac atcactaatg gctcatctat
    19501 ttttccaagc ctctagtcag aacctaacta caaacgtaag aagtttgact aagctctaaa
    19561 tagcaagtca aactagggtg gactacctac tcaagttcga gtacaattct aaggtgtctt
    19621 aagctgggac aataaacaat tacatcgtag taattgtttg gttttcctta gttcagtata
    19681 gataaattga tataaattag gagtaaaaaa tggctgaaac aaaagtaatg gccttgcgtg
    19741 aagcgattaa cttggctcaa agcgaagaaa tgcgtaagga tgaaaaagta ttcttgatgg
    19801 gtgaagacgt cggtatctac ggcggtgact ttggtacatc tgttggtatg ttggacgagt
    19861 ttggtccaaa acgcgttcgc gacacgccta tctctgaggc tgcaatcgct ggttctgcgg
    19921 ttggtgcagc tcaaacaggt cttcgtccaa tcgttgactt gactttcatg gacttcatca
    19981 caattgccct tgatgcaatt gttaaccagg ctgccaaaac caactacatg tttggtggtg
    20041 gtttgaaaac acctgtaact ttccgtgtgg cttcaggttc aggtatcggt tcagcagcac
    20101 agcactcaca gtctcttgaa gcttggttga ctcacattcc aggtatcaag gtggttgcac
    20161 ctggtactgc taacgatgca aaaggtcttc tgaaatcatc tatccttgac aacaacccag
    20221 ttatcttctt ggagccaaaa gctctttacg gtaaaaaaga agaagtgaac ttggatccag
    20281 atttctacat tccacttggt aagggtgaaa tcaaacgtga aggtactgat gtaaccatta
    20341 tttcatacgg tcgtatgttg gaacgtgcct tgaaagcggc tgaagaagtg gctgctgaag
    20401 gtatcagcgt agaagtggtt gacccacgta cccttatccc attggataaa gaattgatca
    20461 tcgaatctgt gaagaaaact ggtaaggtta tcttggttaa cgatgcttac aaaacaggtg
    20521 gtttcatcgg tgaaatcgca tcaatcatca cagaaagcga agcctttgac tacttggatg
    20581 caccaatcat ccgtatcgct tcagacgatg taccagttcc ttacgcaaac attcttgaaa
    20641 acgcagtatt gccaaacgta gagaaaatca aagcggcaat ctataagcaa gtaaacaagg
    20701 gttaatttta tcgtcatcca cttatctttt ctggctgtgt tgatttggct tgcctaacgt
    20761 aagttatgcc tgcaccaaat cgccttgtca gaaaagcaat cggaaagacg ataaccctaa
    20821 tatgctagaa ataaaatgtt ctagcatgac taagaatgct tggaaaagaa ttgagccgct
    20881 tcgattatcg aagtctggtt tggttcttga caaggtaaga aactgaaaga aaggaattga
    20941 acccgtccgg aaaactcgga aaaaagataa atcgttacga aaatcaggat tttctacgat
    21001 ttcctatttt tcattcgttt tctgttcgga cttggtatct taataatggc tattgaaatc
    21061 attatgccta agctcggtgt ggacatgcaa gaaggtgaaa tcatcgagtg gaaaaaacaa
    21121 gagggcgatt ttgtcaacga aggcgacgtc atcttggaaa tgatgtctga caagaccagc
    21181 atggagctgg aagcagaaga gtcaggcgtc ctattgaaaa ttgttcacgg aaacggtgct
    21241 accgttcctg taacagaagt tattgcctac atcggtgctg aaggtgaaac ggttgaagcc
    21301 ggcgcttcat ctgctcctgc tgttgaacca gcagcggcta ttgaagaagt acctgcgggt
    21361 cgtacaccag taatcgttgc tcctgcaact gctgccaaac cacaaggtag tggcaaggtg
    21421 cgtgcaacgc cagctgcgcg taaattggcg cgtgagcttg gaatcgactt gggtcttgtt
    21481 ccaggaacag gtgctaacgg tcgtgtccac aaggttgacg tcgaagactt caagggagca
    21541 gctccaaaag caactccgct tgcagcccgt attgcagcag accaaggtgt tgacttgtca
    21601 acccttacag gttcaggtgt caacggtaag attgtcaaga acgacgttct tgcagtactt
    21661 gctcctgtag ctgtagaaac tgctgctcca gtaccaaaag cagaagaaaa accagctaaa
    21721 gaattgccag aaggcgttga aatcatcaag atgagcccaa tgcgtaaggc gatttcaaaa
    21781 ggtatggtca actcttactt gactgctccg acatttacac ttaactacga tattgacatg
    21841 accaacctca tggcacttcg taagcaagtc cttgagccaa tcatgaacaa gactggtttg
    21901 aaagtaacct ttacagactt gatcggtctt gcggttgttc gtactttgat gaaagaagaa
    21961 caccgttaca tgaacgcatc tttgattaac gatgcacaag aaatcgaatt acacaagttc
    22021 gtcaaccttg gtatcgcagt gggtctagat gatggcttgg tggttccagt tgttcacggc
    22081 gcagataaga tgagcttgtc tgactttgtg gtggcttcga aagatgtcat caagaaggct
    22141 caatctggta agttgaaggg ggctgaaatg tcaggttcga ccttctctat caccaacttg
    22201 ggtatgtttg gtactaaaac ctttaaccca atcatcaacc aaccaaactc agcaatcctt
    22261 ggtgtagcat caactgttca aacaccagtt gttattgacg gcgaaatcaa gatccgtcca
    22321 atcatggcac tctgcttaac catcgaccac cgtatcattg atggtatgaa tggtgctaag
    22381 ttcatggttg acttgaagaa cttgctggaa aacccattgg aattgttgat ctgagataag
    22441 atgcaaaagg cgttaagaaa aacgtatgaa aataggaaat caacgatgtg ctttgaggca
    22501 cgaggcgatt tatctttttc aataggtttt tagcctgtgc tcaatttggt aaagagaaaa
    22561 aataaagaaa gggaataaga gcgagagagt tttagcaatt gaacccgagc ggaaagctcg
    22621 gaaaaaagat aaatcgttta gaaaatcagg attttctacg atttcctatt tttcagtcgc
    22681 tttctcttcg ctcttggtat cttaactatg gcaattgaaa ttattatgcc gaaacttggt
    22741 gtagatatgc aagaaggcga aatcatcgag tggaaaaaac aagagggcga ttttgtcaac
    22801 gaaggcgatg ttatcttgga gatgatgtca gataagacaa gtatggaatt ggaagcggaa
    22861 gaatcaggtg ttcttttgaa aatcgttcat ggcaacggtg caacagttcc tgtaacagaa
    22921 gtcattgcct accttggtgc agaaggcgaa tcagttgaag tgggtgctgc actagctcca
    22981 gctgaggttg ctcaagcaac tgctgacttg aaagcagctg gtttggaagt tcctgcaaca
    23041 cctgcagcag ctccacaagc tcctaaggct gaattggcag cagacgagta tgacatggtt
    23101 gttgtcggtg gtggtcctgc tggttactac gctgctatcc gcggtgctca attgggcggt
    23161 aaaatcgcta tcgttgagaa atcagaattt ggcggtacct gcttgaacaa gggttgtatc
    23221 ccaactaaga cttacctcaa aaacgctgaa atccttgacg gcttgaagat tgcggctgag
    23281 cgtggtatca accttgcttc aacaaactat accgttgata tggacaagac agttgacttc
    23341 aagaacaagg ttgtgaagac attgactggt ggcgttcaag gtctcttgaa agctaacaag
    23401 gtaacaatct tcaacggtct tggtcaagtg aatcctgaca agactgttgt catcggcgac
    23461 aaggtcatca aaggtcgtag catcatcctt gcaacaggtt ctaaagtatc acgcatcaat
    23521 atcccaggta ttgattctaa gttggtattg acttctgatg atatccttga cttgcgtgaa
    23581 attcctaagt cacttactgt tatgggtggt ggcgtagtcg gtgtagaact tggtttggtt
    23641 tacgcatcat acggcacaga agtaaccgtt gttgaaatgg ctgaccgtat cattccaggt
    23701 atggaccgcg aagtgtctgt tgaattgcaa aaagtccttt ctaagaaagg tatgaaattc
    23761 ttgacatctg ttggtgtatc tgaaatcgtc gaagccaaca accaattgac aatcaagttg
    23821 aatgacggct cagaaatcgt ttctgaaaaa gcccttcttt caatcggtcg tgtaccacaa
    23881 ttggctggtc ttgaaaatct taaccttgaa ctagaccgcg gtcgtatcaa ggttaacgaa
    23941 taccaagaaa catcaatccc aggtatctac gcaccaggtg atgtcaacgg tactaagatg
    24001 ttggctcacg ctgcttaccg tatgggtgaa gtggcagctg aaaatgccat ccatggtaac
    24061 caccacaagg ctaaattaga cttcacacca gcagcggttt acacacaccc agaaatcgct
    24121 atggttggtt tgacagaaga ccaagctatc gagaaatacg gtaaagaaaa catccttatc
    24181 ggtcgcaata gcttcactgg taacggtcgt gctattgctt ctaacgaagc ccatggtttc
    24241 gtaaaagtta tcgctgataa gaaataccat gaaatccttg gggttcacat catcggtcca
    24301 gttgcagctg aaatgatcaa cgaagcagca actatcatgg aatctgaatt gactgttgat
    24361 gatgtggcag catcaatcca cggtcaccca accttctcag aggttatgta tgaagccttt
    24421 cttgatgttc ttggtgttgc aatccacaac ccaccaaaac gcaaataata agctaagcaa
    24481 aaagaaagtc catgtggctt tcttttttgt gatatattac taattgctag tattttcttg
    24541 tggtaataga ttttttgata gcggcaaata ctgaacagca atgcgatttt ctggctgacg
    24601 atcgtgcaga tagatgacga tgaggaagag ccattcggct ggtttcatga tcagatagat
    24661 cagatccgcc tgccaagctt tgcgaatatg tttggaaatg ggatagccat accggtcgta
    24721 gttggaacga acgcaacgat gcaggcgtgg acatctttct tctaaaattt gttcaaaagc
    24781 attggcaatt tgtagctgac gattgaccac cacacgatgt ccatggcgtt cccccatacg
    24841 aatgggtttg accagtttac ggtgaccagc agcccccact gtacaaagat agtgttcatc
    24901 atagaatgcg tttggtgggg agattttttc cgacaaggcc caatcactgg tttccgtcca
    24961 catctgaagt agctggtcag gtttttgacc aaagagaatg agataggagc caagaactgc
    25021 aagataggga agactgaaga agaggagcca aattggcaga gaaaggcttt tttgcaggag
    25081 agcagaaagt ctaggaaagc gtgggttgct ctgcttggct aattctgctt gccacagttg
    25141 aatggtttgt aaaattgtcc gactgtaaat gagacaaata ttgaaaggaa ccaaacacag
    25201 gtagcagtag gtgaagaaat ctgtttcaat caaactagaa agttgtatag tccacaaaac
    25261 agcaaagaca aaacttggat ataggcagct gatgaggagg accgttagga gaggggggag
    25321 gagcttagtt tggaagatgt ttagcaccaa ataagctaaa acacccaaaa ggagtaggaa
    25381 aaactgccct gaccaggctt cggtctgcat tgggctgtgg atctggttat taaccaaggt
    25441 ttctggccaa tcgacgtaaa caacttgagc catttcaaga gccaaccaac ttagccctgt
    25501 tcctaaaaag aaaatcaaac catcgttaat ccaaaaacta tactctttta actgtttttt
    25561 caaaaggtcc caaaaatggc ggatgttttt ccaggtcaga taaagaggaa gtacaaagca
    25621 gataagtggc gcattgataa accacataaa aggaagaaag atgcttgcgg ctagataaaa
    25681 gatcaaaaat gattttaagt gtttgctcat gaaaacctcc ttttatagcc taccatcatt
    25741 tttgagaaaa ttcaagaatg gacaagaaga gtttcaatac ttgtcttttg ttatcgtttc
    25801 cactataata aaaattagtt aacaataaag gagttttgca tgaaatacat tgtaaataac
    25861 agcaatgacc cagcttataa cattgccctc gaagcctatg ccttcaagga attaacagat
    25921 attgacgaaa tttttattct ctggatcaat gagcctgcca tcattatcgg taagcaccag
    25981 aatgctattg aagaaatcaa caaggaattc acagacgaaa agggcatcca tgttgttcgc
    26041 cgtctgtcag gtggtggcgc agtttatcac gacctaaata acctcaacta tactattatt
    26101 tcaaataagg cagacgaggg agcctttgac ttcaaaacct tctccaaacc tgtgattgat
    26161 acccttgcaa cactgggtgt agaggccaat ttcaccggtc gtaatgacct ggaaatcgac
    26221 ggaaagaaaa tctgtggtaa cgcccaagcc tatgccaaag gtcgcatgat gcaccacggt
    26281 tgcttgctct ttgatgtgga tatgtcagtc ctcgcaagtg ccctcaaggt cagcaaagac
    26341 aaaatcgagt ccaaaggtgt taaatccgtt cgtgcccgtg tgaccaacat taacaacgag
    26401 ttgccagata agatgaccgt tctggagttc aaggatgcca tcctcaacca aatgaagcaa
    26461 gaatatccag aaatggatga atatgtgttg actgaggatg atttggctcg aatccaagaa
    26521 atccgtgatt cgcagtttgc aacatgggat tggacctacg gtcaaacacc agaatacact
    26581 gtggagcgca gcgttcgtta cccggctggt aaaatcacaa cctatatcaa ggctgaaaaa
    26641 tctgtcatcg aatccatcaa gatttacggt gacttcttcg gtattgggga tgtagctgat
    26701 gttgaagact tactagttgg tacacgttat gaatatgcgg atgtacttgc taaacttcaa
    26761 gagattgata ctactcatta tttctcgcgt atgacaacag aagaagtcgc aaaagcgatt
    26821 gtagcttaat tcatagggct gccctttgtt tgggcagtct ttattttttg tga
//
LOCUS       DBNFCO010000023        26743 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.023, whole genome shotgun sequence.
ACCESSION   DBNFCO010000023 DBNFCO010000000
VERSION     DBNFCO010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 26743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26743
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.023"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            221..2746
                     /gene="secA"
                     /locus_tag="AC1PIV_000802"
     CDS             221..2746
                     /gene="secA"
                     /locus_tag="AC1PIV_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HIP6611839.1"
                     /translation="MVTNVLRSLIENDKGELRKLEKMADKVFSYADEMEALTDEQLQA
                     KTAEFKERYNNGESLDDLLYEAYAVVREGARRVLGLYPYKVQVMGGIVLHNGDVPEMR
                     TGEGKTLTATMPVYLNALSGQGVHVVTVNEYLSTRDATEMGELYSWLGLSVGINLAAK
                     SPLEKREAYNCDITYSTNSEIGFDYLRDNMVVRAEDMVQRPLNYALVDEVDSILIDEA
                     RTPLIVSGAQGSETNQLYFLADNLVKSLTTEDYIIDIPSKTIGLSDSGIDKAEKFFKL
                     DNLYDIENVAITHFLDNALRANYIMTYDIDYLVNEDQEVMIIDPFTGRTMEGRRYSDG
                     LHQAIEAKEGVPVQNESKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVV
                     PIPTNRPIARVDHEDLLYPSLEYKFNAVIADVKRRYEKGQPVLVGTVAVETSDLISQK
                     LVAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGPGVRELGGLC
                     VIGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERIKVFMERMNLT
                     EEESVIKSKMLTRQVESAQKRVEGNNYDSRKQVLQYDDVMREQREIIYRQRQDVITAD
                     RDLAPEIKAMMKRTIERQVAGHFLGSKDEAIDGIIKFAHANLVEDDTLSKATFEAMNQ
                     KEIVEELYERALRVYDSQVKKLRDEERVREFQKVLILRVVDNKWTDHIDALDQLRNAV
                     SLRGYAQNNPIVEYQSEAFTMFNDMIGAIEFEVTRLMMKAQIHDNIERERTSQEAHTT
                     AVKNIMPNQSHAIQENVSFEGVDRNDPCPCQSGKKFKNCHGRK"
     gene            2861..3220
                     /gene="acpS"
                     /locus_tag="AC1PIV_000803"
     CDS             2861..3220
                     /gene="acpS"
                     /locus_tag="AC1PIV_000803"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HIP6611840.1"
                     /translation="MIVGHGIDLQEMEAIESARIKHQGFPKKILTEKEFERYQSLSGR
                     RQLEYLAGRWSAKEALTKALGTGIGKIGFHDIEILNTSKGVPYVTKSPFDGNIWLSIS
                     HSGNFVQASVILEEKDD"
     gene            3213..4316
                     /gene="alr"
                     /locus_tag="AC1PIV_000804"
     CDS             3213..4316
                     /gene="alr"
                     /locus_tag="AC1PIV_000804"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011226530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HIP6611841.1"
                     /translation="MIESEHRPTQIRVNLDAIAENFEQVMTNLPPKTEAFAVVKANAY
                     GHGAVAVAKKLSSQAAGFCVSNLDEALELRKAGIEHPILILGVVPVRFLPVAHQLNIS
                     VTVASLDWLQDAKDLEADLSGLTVHLKLDTGMGRIGFRKIADLLQAIAILEELEYDIE
                     GVYTHFATADEVEQAHFESQLSVFKEFLDVLPITPRWIHASNSATSIWHADTVFNLVR
                     LGNILYGLNPSGRVLELPFGVQPALSLVSEIVHVKQVEAGTTIGYGATYHSTDSEWIA
                     TVPIGYADGLVRSLQGLSVLVDGQACEIVGRISMDQITIRLPRAYPLGQKVTLIGQDG
                     DKTISVQEWADRIGTINYEVVCLLTDRLPRIFE"
     gene            complement(5255..6610)
                     /locus_tag="AC1PIV_000805"
     CDS             complement(5255..6610)
                     /locus_tag="AC1PIV_000805"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HIP6611842.1"
                     /translation="MKVIKFGGSSLASAGQLEKVFNIVQSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYKEYVNGKDVTASQEWIINRYQAMVDELGFTANSMKKIADSIISLAS
                     LPIDDNEFLYDAFLAAGEDNNAKLIAEYFTHRGLPARYVHPKKAGIIVSSEPGNARIL
                     PSSYDKIEELRDTDEVLIIPGFFGVTVDNQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIKNPHSIKELTYREMRELAYAGFSVLHDEALLPAYRGRIPLVIKN
                     TNNPTHPGTRIVHKHTEQTVPVVGIAADDGFVSINLSKYLMNREVGFGRKVLQILEDL
                     NIRWEHMPTGIDDLSIVVRERELTPIKEEEILRQLNTKMEVDKAEIEHGLSIIMIVGE
                     NMKSHVGVTATATTALSKQNVNLAMISQGASEVSVMFVVKTEEKKRALHALYEAFFNE
                     Q"
     gene            6787..7428
                     /locus_tag="AC1PIV_000806"
     CDS             6787..7428
                     /locus_tag="AC1PIV_000806"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HIP6611843.1"
                     /translation="MVKAIIFDMDGVLFDTETFYFQRRADFLATKGLSVDHLDPSIFV
                     GGRASQIWQRILGDDYDNWDVPALEEEYRVYKEKRPTPYAERIFPEVKAVLERLTIQG
                     IPVVLASNTDRSEIERALLDAGIRFHFSHVFSAMDCEAPKPDPTVYMKAASATGVAKS
                     DILVFEDSAKGIEAAKKAGLTVWAIRDQHYGIDQSKADKLVDNLEDAFDLLRF"
     gene            7864..8655
                     /locus_tag="AC1PIV_000807"
     CDS             7864..8655
                     /locus_tag="AC1PIV_000807"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HIP6611844.1"
                     /translation="MAYQTIRYEVIDSVAILTLNRPEVANGFNIPMCEEILEAIRLAE
                     GDASVKILQIQAQGSIFSVGGDLVEMKRAVDDDDIASLVKIAELVNDISFAMKKLSKV
                     VIMVTDGAVAGAAANMAVAADFVIASSKTKFIQAFVGVGLAPDAGGLFLLSRAIGANR
                     ASHLAMTGEGLSADKALEYGIIYKLAEPEKLEKTVAQVIKKLLRGSVNSYAAIKQLTW
                     ESQFKDWESYRRLELDLQETLAYKEDFKEGVRAHAERRRPVFTGD"
     gene            8735..9169
                     /locus_tag="AC1PIV_000808"
     CDS             8735..9169
                     /locus_tag="AC1PIV_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HIP6611845.1"
                     /translation="MEDPKVNEYLTAIFNNVLVIEETSLRGSRFNDISIKEMHTIDVI
                     GSIDGATPSDVARTLMVTLGTVTTSLNNLERKGYVERIRSTKDRRVVHLYLTKKGRLV
                     YRLHQRFHNEMVKQITDGMDDAEYQVMKKGLMKLYHFLEDLK"
     gene            9166..10143
                     /locus_tag="AC1PIV_000809"
     CDS             9166..10143
                     /locus_tag="AC1PIV_000809"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HIP6611846.1"
                     /translation="MRNHAKISQVAHYLPKKIVTNDDLAQRMETSDEWIRSRTGIGQR
                     HIVTGETTSDLASQVARKLLEKSQLDASEIDFIIVATITPDASMPSTAAMVQAAIGAK
                     NAFAYDLVAACSGFVFALSTAEKLLASGVYKRGLVIGAETLSRSVDWSDRSTAVLFGD
                     GAGGVLLEACEQPTFLAEILRTDGGRGASLTAGIDQKETPFSTQSCQQPFIQMEGRAI
                     FEFATRDVTATMAELLEQADMTVDCVDYFLLHQANIRILDKMARKLGVAREKFPANMD
                     KYGNTSAASLPILLSECVESGMLRLDGSQTILMAGFGGGLTWGTLLLQL"
     gene            10203..10427
                     /locus_tag="AC1PIV_000810"
     CDS             10203..10427
                     /locus_tag="AC1PIV_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000035 - acyl binding [Evidence IEA];
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HIP6611847.1"
                     /translation="MAVFEKVQEIIVEELGKDAEEVTLTTTFEDLDADSLDLFQVISE
                     IEDAFDIQIDTEEGLTTVGDLVAYVEEKTK"
     gene            10600..11565
                     /gene="fabK"
                     /locus_tag="AC1PIV_000811"
     CDS             10600..11565
                     /gene="fabK"
                     /locus_tag="AC1PIV_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018580 - nitronate monooxygenase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HIP6611848.1"
                     /translation="MKTKITELLDIKYPIFQGGMAWVADGDLAGAVSNAGGLGIIGGG
                     NAPKEVVKANIDKVKSITDKPFGVNIMLLSPFADDIVDLVIEEGVKVVTTGAGNPGKY
                     MERLHAAGITVIPVVPSVALAKRMEKLGVDAVIAEGMEAGGHIGKLTTMTLVRQVVEA
                     VSIPVIAAGGIADGAGAAAAFMLGAEAVQVGTRFVVATESNAHQAYKEKVLKAKDIDT
                     TVSASIVGHPVRAIKNKLSSAYAAAEKDFLAGKISADAIEELGAGALRNAVVDGDVTN
                     GSVMAGQIAGLVSKEESCEDILKDIYYGAAKVIREEASRWASVGE"
     gene            11567..12487
                     /gene="fabD"
                     /locus_tag="AC1PIV_000812"
     CDS             11567..12487
                     /gene="fabD"
                     /locus_tag="AC1PIV_000812"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HIP6611849.1"
                     /translation="MTKTAFLFAGQGSQTVGMARDLYEYYPIVRETFDQASQILGYDI
                     RDLIDNQEDKLHQTRYTQPAILTTSVAIFRLLEEEGIQPDMVAGLSLGEYSALVASGA
                     LAFEDAIALIAKRGEYMELAAPAGTGKMVAVLNTDVNLIEEICATVTSGIVSPANYNT
                     PAQIVIGGEVAAVDEAVELLKEAGVKRMIPLNVSGPFHTALLRPASEQLAQALEQVEL
                     ADFQVELVGNTEAEVMKKEDIKSLLPRQVMEPVRFYESIATMQEAGVTNFIEIGPGKV
                     LSGFVKKIDKTAHVVAIEDIEGLQIVLNKS"
     gene            12497..13231
                     /gene="fabG"
                     /locus_tag="AC1PIV_000813"
     CDS             12497..13231
                     /gene="fabG"
                     /locus_tag="AC1PIV_000813"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011225529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HIP6611850.1"
                     /translation="MELTNKNVFVTGSSRGIGLAIAHKFASLGANVVLNGRGQLGQDL
                     LDSFADYGVKVLAISGDISSAQDAKRMVAEAIETLGSVDILVNNAGITKDGMALRMTE
                     EDFDTVLKVNLTGTFNMTQAVLKPMTKAREGAIINLSSVSGLIGNAGQANYSASKAGV
                     IGFTKAIAREVAGRNVRVNAIAPGFIQSDMTDVLSDKIKEAMTAQIPMKRFGATEEVA
                     DVAVFLAKQEYLTGQVIAVDGGLTMQ"
     gene            13257..14492
                     /gene="fabF"
                     /locus_tag="AC1PIV_000814"
     CDS             13257..14492
                     /gene="fabF"
                     /locus_tag="AC1PIV_000814"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HIP6611851.1"
                     /translation="MTKLNRVVVTGYGLTSPIGNTPEEFWNSLKAGKIGIGKITKFDT
                     SEYSVHNAAELKDFPFDKYFVKKDTNRYDNYSLYALYAAKEAIANAQLDTETVDSDRF
                     GVILSTGIGGILEIEEQVARMNEKGPKRIRPMALPKALPNMAAGNIAMQVGANGVCKC
                     IITACASSNDALGEAFREIKFGFQDVMLAGGAEAAITPFAIGGFQALTAMSTTEDPER
                     ASIPFDKDRNGFVMGEGSAVLVLESLEHAEARGATILAEIVGYGNTCDAYHMTSPHPE
                     GLGAIKAMKLAISEAGLEPADIDYINAHGTSTPANEKGESQAIVSVFGKNTPVSSTKS
                     FTGHLLGAAGAVEAAAVIEAMRHSYAPKTAGTTELSEDIEADVIYGQGRDMEIRHAIS
                     NTFGFGGHNSVIAFKRWEA"
     gene            14493..14969
                     /gene="accB"
                     /locus_tag="AC1PIV_000815"
     CDS             14493..14969
                     /gene="accB"
                     /locus_tag="AC1PIV_000815"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HIP6611852.1"
                     /translation="MNITEIKDLMSQFDQSSLREFSYSNAGEILHFSKNQQATVAPSP
                     AVEAPLAPVTPASPAPVPAVEMSEPAPAEAGASPVAEGAVVESPLVGVAYLSPAPDKP
                     AFVAVGDTVKKGQTLMIIEAMKVMNEVPADRDGVVTEILVANQDVVEFGQGLVRIK"
     gene            14966..15388
                     /gene="fabZ"
                     /locus_tag="AC1PIV_000816"
     CDS             14966..15388
                     /gene="fabZ"
                     /locus_tag="AC1PIV_000816"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002922202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0019171 -
                     (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HIP6611853.1"
                     /translation="MIDILKIKEALPHLYPMLLVDRVLEVSEDEIVALKNVTINEPFF
                     NGHFPDYPVMPGVLIMEALAQTAGVLELSKEENKGKLVFYAGMDKVKFKKQVVPGDQL
                     IMTAKFVKRRGTIAVVEAKAEVEGKLAASGTLTFAIGK"
     gene            15682..17055
                     /locus_tag="AC1PIV_000817"
     CDS             15682..17055
                     /locus_tag="AC1PIV_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HIP6611854.1"
                     /translation="MFEKILIANRGEIAVRIIRSARELGIATVAVYSEADKEALHTML
                     ADEAVCIGPARSTDSYLNMQAVISAAVVTGAQAIHPGFGFLSENSKFATLCEEVGIKF
                     IGPSGTVMDTMGDKINARAEMVKAQVPVIPGSDGEVLTSQEALEIAEKIGYPVMLKAS
                     AGGGGKGIRKVEKAEDLVPAFESASSEAKAAFDNGAMYIERVVYPARHIEVQILADQH
                     GHVIHLGERDCSLQRNNQKVLEEAPSIAIGQTMRERIGQAAVRAAQSVGYENAGTIEF
                     LLDEAKGEFYFMEMNTRVQVEHPVTEFVTGVDIVKEQIKIAAGQELSVRQEDVKITGH
                     AIECRINAENPAFNFAPSPGKISTLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKVI
                     VHGENRFEALMKMQRALYELEIDGVVTNTDFQLDLISDKRVVAGDYDTAYLMEEFLPR
                     YQEDLKK"
     gene            17070..17936
                     /gene="accD"
                     /locus_tag="AC1PIV_000818"
     CDS             17070..17936
                     /gene="accD"
                     /locus_tag="AC1PIV_000818"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HIP6611855.1"
                     /translation="MALFRKKDKYIRINPNRSRIESAPQAKPEVPDELFSKCPACKVI
                     LYKNDLGLEKTCQHCSYNFRITAQERRALTVDEGSFEELFTGIETTNPLDFPNYLEKL
                     AATRQKTGLDEAVLTGKATIGGQPVALGIMDSHFIMASMGTVVGEKITRLFELAIEER
                     LPVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTVLTDPTTGGVTASFA
                     MEGDIILAEPQTLVGFAGRRVIESTVRENLPDDFQKAEFLQEHGFVDAIVKRQDLPAT
                     ISRLLRMHGGVR"
     gene            17933..18706
                     /locus_tag="AC1PIV_000819"
     CDS             17933..18706
                     /locus_tag="AC1PIV_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HIP6611856.1"
                     /translation="MTSDVARMIRLARDQARLTTLDYATQLFDDFIELHGDRNFRDDE
                     AVVGGIGFLAGQPVTVIGIQKGKNLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPV
                     VTFINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVAD
                     QVWMLENSMYAVLSPEGFASILWKDGSRAMEAAELMKITSYELEKLQVVDRVVLENGR
                     ATKEVLSDIKDNLVSQLAQLQALPLEQLLENRYQRFRKY"
     gene            18770..19243
                     /locus_tag="AC1PIV_000820"
     CDS             18770..19243
                     /locus_tag="AC1PIV_000820"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIP6611857.1"
                     /translation="MLVKADLSNAEELLPIQHRAFAALYKTYQDQYNPAIETMDYFQS
                     RFARPNCSYYKIIEEEHTVGLVRTTVAEDAEQGWLGLIGIDPDHRGKGYGHKAMLELE
                     SLYPTVRRWVLCTVLQESKLVSFYEKLGYKAIKTEPEQEGMDMVYMEKWIGDSDA"
     gene            19236..19868
                     /locus_tag="AC1PIV_000821"
     CDS             19236..19868
                     /locus_tag="AC1PIV_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611858.1"
                     /translation="MLEQCRRYLDYQGVHYCKPEKAGALAGDMIALKNVAQAARKEFQ
                     TLSLVLAEHVSPFVPERVSQWMNQAQICRPHFWTYYRFPSASLTDSALAIRLYGKGTE
                     AGISVEVSFIERKKVETSLLQQNRVLNCSIAAPLYYWVQEGQVFYRLDGTEENRQSLL
                     QAVEAGRIRKVLVKYDVPFRTVASEEELLERLIQGFSLLEPYLKMTHLAK"
     gene            20046..20291
                     /locus_tag="AC1PIV_000822"
     CDS             20046..20291
                     /locus_tag="AC1PIV_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611859.1"
                     /translation="MEKLGQSLKWLGRKIWLLLRIFGLLVLAVLPDLILEGSKSQVTL
                     VIVGLMTLGLLVFFWWRAEKMICQSGTLTFLLGTVWR"
     gene            20312..20704
                     /locus_tag="AC1PIV_000823"
     CDS             20312..20704
                     /locus_tag="AC1PIV_000823"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamic
                     endopeptidase"
                     /protein_id="HIP6611860.1"
                     /translation="MQLTDMLGYYLLELQGVTTTENDASIIEFLKGVPFRLALLTTAF
                     LPAVVEEVIFRGYFFKKLFGSQVLLGIVVSSLVFGSFHGPTDLGSWLIDAGSGIILSL
                     LYYKSRYLIYPIIVHLVNNFIATVFYYI"
     gene            complement(20758..21684)
                     /locus_tag="AC1PIV_000824"
     CDS             complement(20758..21684)
                     /locus_tag="AC1PIV_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HIP6611861.1"
                     /translation="MNLSKEKLLFHHYYANWLRIYKEGAIREVTLKKYRMTLQWLIRL
                     APSLLLEDLNRVRYQELINSYAKTHERQTTMDFHHQLKGAILDAVDEGIIERDPTRKV
                     IIKGRLPRKKKTKYLNQFELHQLIQELRLGEELNWDWLILLIAKTGIRFSEALALTTQ
                     DFDFHRQLLTIDKTWNYKGDGGFLPTKNKSSIRKIQLDWQTSTQFANLLQHTQPDDLL
                     FVKKERIYNSTINAILEKRCLSANLPVVTIHALRHTHASILLFAGVSIASVARRLGHA
                     SITTTQKTYLHIIRELENQDVDLIMRSLSGLC"
     gene            21805..22383
                     /locus_tag="AC1PIV_000825"
     CDS             21805..22383
                     /locus_tag="AC1PIV_000825"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HIP6611862.1"
                     /translation="MKLEELALFMGGSLQVRLDTTSWEDARDYILYNQQHHQLDGYEV
                     IEEEVIDSRTVTTDREVTLLEEGDLLFSLLSGKAVLVRAEHAGLLYTQNYIKIEPIAK
                     LDKAFLLYLINESSAIRRQFYQSLQGSEVMKYTVKQLKSLQLGALPPLDSQQKLGKIY
                     LDGLALRQKRQAYAQGDFLRLTYLLKEVYSHE"
     gene            22376..25582
                     /locus_tag="AC1PIV_000826"
     CDS             22376..25582
                     /locus_tag="AC1PIV_000826"
                     /EC_number="3.1.21.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009035 - type I site-specific
                     deoxyribonuclease activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HIP6611863.1"
                     /translation="MNELAFETELIQYITTGTITQPEHLEGLEWSVSDSSTLYAVKSK
                     LWTYEPGIKTTEQLWENFRNILWQHNQHRLDKPLSDTEFAQVKQIISDLKTPYEAGQF
                     LYGISGVSELEITLDDGRHTFLTVFDQRKIGGGDTVYQVVNQIRRTPKIPGRRECIFD
                     TTLLINGLPIIQIEEKKDTVDVDKALNQMHQYIQERQYTDIFSTLQILVAIAPNNVRY
                     MANTTAEKFNKDFAFHWQRKSDGSKVRNWKDFADSMLSIPMAHQMATNYMILDGTPQK
                     QMLKVMRPYQVYATHAVIEGIKKVDFELGCNKVGYIWHTTGSGKTITSFKTAWLASRM
                     PKVDKVVFLVDRIALTNQTKDDYLAYDPEAGENSFGSIRETQNTTALARQLTSKDSGI
                     IVTSVQKLDTLVKRKSFKSPDKHIVFIVDEAHRSTGGDSFAGIQKAFKKAAWIGYTGT
                     PNLDDTGASLQTQDIFGPLLHAYTIKNAISDRNVLGFKVDFETTIDQEKLKTTYLPDF
                     YRQKYPKWTSAQIEEKIANLSPDDMDDAVTSSVYDENPEHVRLVVEDVFKHWANRSGS
                     GRYNALFTTHVGGGRASTPMAMMYFREFQRINQLHREQGGLVLKVGLTFALNTQNNDS
                     MVESNTGLLEAITIYNTEFGTSFGLSDVAAYTEDLISRLNRTAQDKNYLDLVIVVDQL
                     LTGFNAPELNTLYVDRTLKGASLIQAYSRTNRVEDMDKKPFGRVVNYRWPAHNEKLMN
                     QALAIYADDSAANLSDAEQKNNNEKNGLVAKPFKEVFAEVKQTVDQLRELTGDFNDIP
                     KSEKKREAMLELLRAYNQGLSKLKQYQPEEVDGVIEGFDYNQPDRFIESLGMSVEEEK
                     LLTTVLANELKRTLAKEQKVSIHQIELKMTHIKEVTIDYDKLTELVELLLNQVHEEKM
                     VEAAATRDELDRFASGLEDLNYADQIRQTGDAIYRGDFPTQDMNFAYPVKGIDSQKII
                     QEASHVYIDKKLFAFRIQWGLTEHIRNQELRELLTRHRYGQNDLDDTGHLRTLIKEAS
                     RDYQTWAEGDAVKGLSKIQYRNQLRQALYDLADDLVGQ"
     gene            25690..>26743
                     /locus_tag="AC1PIV_000827"
     CDS             25690..>26743
                     /locus_tag="AC1PIV_000827"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HIP6611864.1"
                     /translation="MTKEKSTVPRLRFPGFTDAWKQRKLGEVADFSIKTNSLSRDKLS
                     SYFYEVQNIHYGDILTKYDAILDVCNKELPSIIGSTISDFADALLSEGDIVFADAAED
                     STVGKAIEVRNFKGKNVVSGLHTIVARPKVSYAPYYLGYLINSTAYHNQILPLMQGTK
                     VSSISKANLKSTTVVFPTLPEQEAIGSFFSDLDQLITLHQRKLDDVKELKKALLQKMF
                     PKGNGNDFPELRFPEFTDAWKQRKLGEFMKESKILGSKGDIARKLTVRLWGRGVVSKK
                     EIYSGSSATQYYIRKSGQFIYGKLDFLNQAFGIIPPELDGYESTLDSPAFDLLKGING
                     QFLLEFVSRKEFYYYQG"
BASE COUNT         7770 a         5051 c         6412 g         7510 t
ORIGIN      
        1 atttctaaat ctccgatata tcgcagattc ctcatttaaa attttataaa tttttcacct
       61 cctaggagtt attgtgacta ggaggtgttt tgtggtaaaa atagtaatat taagctagca
      121 ttttcattta tttaggctgt atcctagtgc caaaccttga aaattgccta gttttctgct
      181 acaatatatt attgactaaa actgaaatag gatgaaatgt atggtaacaa atgtacttcg
      241 ttctctcatt gaaaatgata agggagagct aagaaaactt gagaaaatgg cagacaaggt
      301 cttctcgtat gccgatgaaa tggaagcgct gactgatgaa cagttgcaag ctaagacagc
      361 agaatttaag gagcgctaca ataacggtga atccctcgac gatcttttgt acgaagctta
      421 tgcggtagtc cgtgaaggag ctcgacgtgt cttgggtctc tatccctaca aggttcaggt
      481 tatgggagga atcgttcttc acaacggtga cgttccagaa atgcgtacag gtgaaggtaa
      541 aactctgact gcaacgatgc ctgtttattt gaatgccttg tctggtcaag gtgttcacgt
      601 agtgacggtt aacgagtatc tttctacccg tgatgcgact gaaatgggtg aattgtattc
      661 atggcttggt ctatcagttg gtatcaactt agctgctaaa tcacccttgg aaaaacgtga
      721 ggcctataac tgcgatatta cttattcgac caactcagag attggttttg actatctccg
      781 agacaatatg gttgttcgcg cagaagacat ggttcaacgt cctctcaatt atgccttggt
      841 cgatgaagtt gactcaatct tgattgatga agctcgtacg ccgttgattg tatctggtgc
      901 acaaggttcg gaaacaaacc agttgtattt cttggcagat aatcttgtta aatctttgac
      961 aacagaagat tacatcattg acattccatc taaaacgatt ggactgtctg attcaggtat
     1021 tgacaaagca gagaaattct tcaagttaga taacctctac gatattgaaa atgtagccat
     1081 tacccatttc ttggataatg cacttcgtgc caactacatc atgacctatg atattgacta
     1141 tctggtcaat gaagaccaag aggtcatgat tatcgatcca tttacaggtc gtacgatgga
     1201 aggtcgtcgt tattctgatg gacttcacca agccatcgaa gctaaggaag gtgtaccggt
     1261 tcaaaacgag tctaagacaa gtgcctctat tacctaccaa aaccttttcc gtatgtataa
     1321 aaagttatcg gggatgacgg gtactggtaa aacagaagag gaagaattcc gtgaaatcta
     1381 caacatccgt gttgtaccaa ttccaaccaa ccgtccaatc gcgcgtgttg accacgaaga
     1441 tttactctat ccaagtctag aatacaaatt taatgccgtt attgctgatg tgaagagacg
     1501 ctatgagaaa gggcaacctg tcttggtcgg tacagttgcg gttgaaactt ctgatttgat
     1561 ttctcaaaaa ttggtagctg caggtgtccc tcacgaagta ttgaatgcta aaaaccacta
     1621 tcgtgaagca cagattatta tgaatgctgg tcagcgtggt gcggtcacta ttgcgaccaa
     1681 catggcggga cgcggtaccg atattaagtt aggtccaggt gtacgtgaac ttggtgggtt
     1741 gtgtgttatt ggtactgagc gccatgaaag tcgtcgtatt gataaccagc ttcgtggacg
     1801 ttcaggtcgt caaggggacc caggtgaatc acaattctat ctatctctcg aagatgactt
     1861 gatgaaacgc tttggttcag aacgcatcaa agtatttatg gagcgtatga atctaacaga
     1921 agaagagtcc gttatcaagt ctaaaatgtt gacacgtcaa gttgaatctg ctcagaagcg
     1981 tgtggaaggg aacaactacg actcacgtaa acaagtcctt caatatgacg atgtgatgcg
     2041 tgagcaacgt gaaatcatct atcgccaacg ccaggatgtt attactgctg accgtgattt
     2101 ggctcctgaa atcaaagcga tgatgaaacg gacgattgaa cgccaagttg cgggtcactt
     2161 ccttggttcg aaagatgaag ctattgatgg tattatcaaa tttgcgcatg caaatctcgt
     2221 tgaagatgat accttgagta aagctacttt tgaagcaatg aatcagaaag agattgtcga
     2281 agagctctat gaacgtgctt tgagagtcta tgattcgcaa gtgaaaaaat tacgcgatga
     2341 agaacgtgta cgcgaattcc agaaagttct tatccttcgt gttgtggata acaaatggac
     2401 agaccatatt gatgccttgg atcaattgcg caatgcagtc agtcttcgtg gatacgctca
     2461 aaacaatcca atcgttgaat atcaatcaga agcatttact atgttcaacg atatgattgg
     2521 ggctatcgag tttgaagtaa cccgcttgat gatgaaggcg caaattcatg acaatattga
     2581 gcgtgagcgt acaagtcaag aagcacatac gacagctgtt aagaatatta tgccgaacca
     2641 atcgcatgca attcaggaga atgtatcttt tgaaggtgtt gatcgtaacg atccatgccc
     2701 atgccagtct ggtaagaaat ttaaaaattg tcacggccgt aaataggaat gacgcgtgga
     2761 ctggacggct gtccagtcct tttgcaattt ttagacaagt cactagagtc agttcgttta
     2821 ttttaataaa tgaagtgact atgcaaaagg agaccgatta atgatagtag gacatggcat
     2881 tgaccttcag gagatggagg cgattgaaag tgccagaatc aaacaccaag ggtttcccaa
     2941 aaagattctc acagagaaag aatttgaacg gtatcaaagt ctgtccggtc gccgtcagct
     3001 agaatattta gctggacgtt ggtcagccaa agaagcactg accaaggcct tggggacagg
     3061 cattggtaag ataggatttc atgatattga aattctgaat accagcaaag gagttcccta
     3121 tgtgacgaag agtccctttg atgggaatat ttggctcagc attagccatt caggaaattt
     3181 tgtacaagct agtgtgattt tggaggagaa agatgattga aagtgaacat cgacccacgc
     3241 aaattcgggt taacttagat gcgattgcgg aaaatttcga gcaagtaatg accaacttgc
     3301 cccctaagac tgaagcattt gctgttgtta aggcgaatgc ttatggtcat ggagctgttg
     3361 cggtagcgaa aaagttatcc agtcaagcag ctggtttttg tgtttcgaat ttggatgaag
     3421 cattagagtt acgtaaagcg ggtatcgagc atcctatctt gattttagga gtggttcctg
     3481 tacgtttttt accagtagct catcaactca atatcagtgt gacagttgcc agtctggact
     3541 ggttgcaaga tgcaaaagac ttagaggctg atttatctgg tctaactgtc catcttaagc
     3601 tggatacagg tatggggcgg attggtttta gaaaaatagc cgatttgcta caagcgattg
     3661 ctatccttga agaattagag tatgacatcg aaggagtcta tactcatttt gctactgcgg
     3721 atgaggttga acaggcgcac ttcgagagtc aactgtctgt ttttaaagaa tttttggatg
     3781 ttctaccaat tactccgcgc tggattcatg ccagcaattc agcaacaagc atttggcatg
     3841 ctgatacagt atttaacctg gttcgtttgg gaaacattct ttatggactt aatccaagtg
     3901 gacgagtact agaactcccg tttggtgttc aaccagcctt atctctcgta tctgaaattg
     3961 ttcatgtaaa gcaggttgaa gctggcacaa caattggcta tggagctact tatcacagca
     4021 ccgattcaga atggattgcg accgttccga taggatatgc agatggtctc gtacgaagct
     4081 tacaaggctt atcagtccta gtcgatgggc aggcctgtga aattgtaggg cgtatttcga
     4141 tggaccagat caccattcgt ttacctcgtg cttatccact tggtcaaaaa gtcaccctaa
     4201 tcggtcaaga tggagataaa acgatctctg ttcaggagtg ggctgatcgc atcggaacca
     4261 taaattacga ggtggtttgt cttttgacag atcgtctacc tcgaattttt gagtaaacgt
     4321 gatgataatc cgcttctttc actaaaatag aaggctaaaa tattagagaa gtgttgccta
     4381 gagattgtct ataatacaaa tatcgtcatt tagttgcctt ttattacttt gacaatcgag
     4441 gaaatatcgt ttccatattt ccaacttcaa acactccacc ggattgtttg aactcgcctt
     4501 gcctgatttt gtaaaagtga cttgctttgc aagtattatc tcccaccttg cacagtccat
     4561 tgactgtgca agcaatctgg gggatacgaa tagtccagtg gactattcgt acctgagcct
     4621 gaaaacaaaa aagcgaagta catcagctgg tcacctagaa ataagaaagc attgagttat
     4681 gcctgtggct tttgatgagg ctgggcaaaa agtccaggac cactactcag agttcgtgtc
     4741 aacatctcag cgcagtggtt gattggcata tttgttcgtg ttttgcactc caaatctggc
     4801 ctaatcaact gtgcgggggg tgggaagacg aactcttttt atcttggtcg agttctttcc
     4861 cactcccttt gtccccagtc tccaactatc tcccagatag ttggagcgag tactaaaagt
     4921 aaactaaaag actataatga ggctggtcaa aaagtccaat actcttcgaa aatcaaaatt
     4981 atccgttgtc aacttgcctt gatgaactcc agttctatct tcgacttcgt ttcctaggct
     5041 acttttgatt ttcattgagt ataaaaaata aaaaatagct tagaattgca tcgtcagaaa
     5101 cgttgattct aagctatttt tgtttattca aattttaatt ggtactcaat gaaaattaaa
     5161 atcagactag ctccaatgga gcttgacact catcaaatca agtcaacaac gtctggtttt
     5221 gattttcgaa gagtatgaag cgacctcgtt gtgattattg ctcgttaaaa aaagcttcat
     5281 agagtgcgtg cagggcgcgt ttcttttctt cggttttgac aacgaacata acagaaactt
     5341 cactggctcc ctgtgaaatc attgccaagt tgacgttttg tttagagagg gcagtggtag
     5401 cggtagctgt tacaccgaca tggctcttca tattttcacc aacaatcatg ataatagata
     5461 aaccatgttc gatttcggcc ttgtcaactt ccattttcgt attgagttga cgaaggatct
     5521 cttcttcctt gataggagtc aattcacgct cacggactac gatggataaa tcgtcaatac
     5581 cggtcggcat gtgctcccag cgaatattga gatcttcgag aatttgcaat accttgcgac
     5641 caaaaccaac ttcacggttc atcaagtatt tggacaagtt aatgctgaca aaaccatcgt
     5701 ctgcagcaat accgacaaca ggaactgttt gctcggtatg tttgtgtaca attcgggtac
     5761 cagggtgagt tgggttattg gtgtttttga taaccaatgg aattcgtccg cgataggcag
     5821 gaaggagggc ttcatcgtgg aggacggaga aacctgcata agctaattct cgcatttcac
     5881 gataggtcaa ttctttgatt gaatgtggat ttttaatgat gccaggatgg gctgcaaaaa
     5941 taccatcgac atctgtaaag ttttcataga ggtcagcctt gaccccggca gcaatgatgg
     6001 aacctgtaat gtccgatcca cctcgtgaga aggtacaaat ctggttatca acagttacac
     6061 cgaaaaatcc tgggataatg agtacttcat ctgtatcacg aagctcttcg attttgtcat
     6121 aacttgaagg caaaatgcga gcatttcctg gttcggagct gacaataata ccagcttttt
     6181 taggatggac atagcgtgca ggcaatcctc tgtgggtaaa atattcggca atcaatttgg
     6241 cattattatc ttcaccagct gctaagaatg cgtcgtaaag gaattcgtta tcatcaattg
     6301 gtaggctggc caaagagatg atgctgtctg cgattttctt catgctgtta gctgtgaaac
     6361 caagttcgtc aaccattgct tgataacggt tgatgatcca ttcttgactg gcagtcacat
     6421 cttttccgtt aacatattct ttataatatt taatcaacgc atcagtaact ttagtatcct
     6481 cggcattgcg ttttccaggt gcagacacca caacaaagcg acgttctgaa tcagattgaa
     6541 caatattgaa aactttttct aactgtccag ctgaagcaag tgagcttccc ccaaatttaa
     6601 taactttcat tctcatctcc ttggatattt ttttctatta tagcagaatg atatgaaatt
     6661 gtcagtatgt tcagacaaat cttgccaaga attttatcga aaaacgaaca agagacaagt
     6721 atgaaaattt cagaaaaaca tttttttctt tcaactgtgt tacaattaaa gtaataggag
     6781 gcgagtatgg taaaagcaat tattttcgac atggatggtg tactttttga tacagaaaca
     6841 ttctattttc aacgtcgagc ggatttttta gcgacaaaag gtttatcggt tgatcatttg
     6901 gatccatcta tatttgtcgg cggaagagct agtcaaattt ggcaacggat tttaggggat
     6961 gattatgata actgggatgt ccctgccttg gaagaagaat atcgtgtgta taaagaaaag
     7021 cgaccaaccc cttatgcaga gaggattttt cctgaagtta aagcggtatt ggagagacta
     7081 actatccaag gtattcctgt agttttggct tcaaataccg accgttcaga aatcgaacgt
     7141 gctctactag atgctggtat acgctttcac tttagtcatg ttttctcagc gatggattgt
     7201 gaggccccaa agccagatcc cacagtttat atgaaagcag ctagtgcaac aggagtagct
     7261 aaatcggaca ttttagtatt tgaagatagt gcgaagggga ttgaagcggc taaaaaagca
     7321 ggtttgacag tttgggctat tcgagaccag cattatggaa ttgatcagtc gaaagcagac
     7381 aaattggtag acaatcttga agatgccttt gacttattgc gattttaaga aatattatat
     7441 tgtagtccaa gcatcagttc tcgtgaaaaa tggtatttct agctcagaat ccagttaaat
     7501 cttccaaaag tattaacgtg aaaaaatgaa agttgtaaat taaacttaga gcctataatt
     7561 tacagttcag acttgcatat tgaggttgtt ttttcaaaat acagtcagta tttcccgcaa
     7621 aactaccttg atgagtgaaa aagccaaggc gctttgcgtg tgaatataga ttcttagaca
     7681 cgttattttc tagcatatct aaattttata ttgcgatgat ggcctccatc tttttcggac
     7741 gtcacacttt ccttgctaga aaaaagtgac aattttaaaa actatgttac aatggaaaac
     7801 aagaaattga agtttgatat tcaaatcttt taattatcaa actattttga aaggagcaag
     7861 agaatggcct atcaaacaat tcgttatgaa gtaattgatt ccgtagcgat tctaacttta
     7921 aacagaccgg aagtggcaaa tggttttaat attcctatgt gtgaagaaat cttagaagca
     7981 atccgccttg cagaagggga tgcctccgtc aaaattttac aaattcaagc acagggttcc
     8041 attttctccg tgggtggaga tttagttgag atgaagcgtg cagttgatga tgatgatatt
     8101 gcttctttgg taaaaatagc agagctggtg aatgatattt cgtttgcgat gaagaaattg
     8161 tctaaagtag tcattatggt gacagatggg gcagtggctg gagccgcggc taatatggca
     8221 gtggcagctg attttgttat tgcctccagc aagacaaaat tcatccaagc ctttgtaggc
     8281 gttggacttg cgccggatgc gggggggctc tttctactga gtcgtgctat tggggctaat
     8341 cgtgctagtc acttggcgat gactggagag ggcttatcag cggataaggc tttagaatat
     8401 gggattattt ataaattggc agagccagaa aaactagaaa agacggttgc ccaggtcata
     8461 aaaaaactct tgcgaggctc agtaaattct tatgcagcaa tcaaacaatt gacatgggaa
     8521 agtcaattta aagactggga gtcttatcgc cgattggagc tggatttaca agaaacatta
     8581 gcctataaag aggattttaa agagggagtt cgagcgcatg cagaacgacg tagaccagtg
     8641 tttacgggag attaattttt aaattagtaa aaaatgtttg acaatcaaag ttttatggtt
     8701 tatactttga ctatcaaagt aaaggaggcc tgttttggaa gatccaaaag taaatgaata
     8761 tctaacggcc atttttaaca atgtgttggt gattgaagaa acaagtctgc gtggtagccg
     8821 attcaatgat atttcgatta aggaaatgca cacgattgat gtgataggaa gtattgatgg
     8881 agctactccg agtgatgttg ctcggacttt gatggtaacc ttaggtactg ttacaactag
     8941 cttgaacaat ttggaaagaa aaggatatgt tgagcgtatt cgttcgacca aagatcggcg
     9001 agttgttcat ctctatctga ccaaaaaagg tcgactggtc tatcgtttgc atcaacgatt
     9061 tcacaatgaa atggtgaaac agattacaga tggtatggat gatgcagagt atcaggtaat
     9121 gaagaaagga ctcatgaaac tctatcactt cttggaggat ttgaaatgag aaaccatgct
     9181 aaaatcagtc aggtggccca ctatcttccg aagaagattg tgaccaatga tgatttggct
     9241 caacgaatgg agaccagtga tgagtggatt cgtagccgta caggtatcgg tcaacggcac
     9301 attgttactg gagagacgac gagtgatttg gctagtcaag tggctagaaa attactggaa
     9361 aagtctcagc tagatgctag tgaaattgac ttcatcatcg tagcaacgat tactccagat
     9421 gcttcaatgc catctacagc agctatggtt caagcagcaa ttggcgcgaa aaacgctttc
     9481 gcctatgatc tcgttgcagc ttgttcagga tttgtttttg cgctatcaac agcggaaaaa
     9541 ttgcttgctt caggagtcta taagagagga cttgtcattg gtgcagagac cctatctagg
     9601 tctgtcgact ggtcggatcg atcaacggct gttttatttg gagatggtgc tggaggagtt
     9661 ttgctggaag cgtgtgaaca accgaccttt ttagcagaaa tcttgcgaac ggatggcggt
     9721 cgaggtgcta gtctgacagc agggatagac cagaaagaga cgccattctc gacacaaagc
     9781 tgtcagcaac cctttatcca aatggagggc agagctatat ttgaatttgc tacgagggat
     9841 gttacggcaa ccatggcaga gctgctagaa caagctgata tgactgtgga ttgcgttgat
     9901 tatttcttgc tccaccaagc caatatacgt atcctggata agatggctcg taaattggga
     9961 gtggcgcgtg aaaaatttcc agcaaatatg gataaatatg gcaataccag tgcagcaagt
    10021 cttcctattc tcttatcaga atgtgtagag agcggaatgt tgcgattgga tggaagccag
    10081 actattctca tggctggttt cggtggaggc ctcacatggg gaactctact cttacaactt
    10141 tagttaattc cttgccctag gcaagattaa aatattttat tttacaaaag gagacacata
    10201 tcatggcagt atttgaaaaa gtacaggaaa tcatcgttga agaattgggt aaggatgctg
    10261 aagaagtaac tcttacaaca acctttgagg atttggacgc agattcattg gatcttttcc
    10321 aagttatctc tgaaatcgaa gatgcattcg acatccaaat cgacactgaa gaaggtttga
    10381 ctactgtagg cgatttggtt gcttatgttg aagaaaaaac aaaataatga ctgttaagga
    10441 gagtgctatg tagcattttt cttaagttaa atactttgat aatcaaaata ttgaaatatc
    10501 aaactatttt ttgagtgagg gggggcaacc cttcacttgt ttacctaatg atttgatatt
    10561 caaatgatta ggtaagcaag aaaaaaagat gagggaatta tgaagacgaa aataacagaa
    10621 ttgctcgata ttaagtatcc aatttttcaa ggtggtatgg cttgggtagc tgatggagat
    10681 ttggctggtg ccgtatctaa tgcaggtggt ctaggaatca tcggtggagg aaatgctccc
    10741 aaagaggtgg tcaaggcaaa tattgacaag gttaaatcta tcacggacaa acctttcggt
    10801 gtcaatatca tgcttttgtc tccttttgcg gatgacattg ttgacttggt catcgaagaa
    10861 ggtgtgaaag ttgtcaccac aggagcagga aatccaggga agtatatgga gcgtctccat
    10921 gctgcaggga ttacagttat tcctgttgta ccgagtgtag cccttgctaa acgcatggaa
    10981 aaattagggg tagatgctgt tattgctgaa ggtatggaag ccggaggtca tattggtaaa
    11041 ttgaccacca tgaccttggt tcgtcaggtt gttgaagctg tatctattcc tgttattgct
    11101 gctggaggta ttgcagatgg tgcaggtgca gcggcagcct ttatgttggg agcagaagcg
    11161 gtgcaagttg gaactcgttt tgtagtagct acagagtcca atgcccatca ggcttataag
    11221 gaaaaagttt taaaagctaa ggatattgat acaactgtat cagcttctat tgttggacat
    11281 cctgtgagag ccatcaagaa taagttgtca tctgcttatg cagctgcaga gaaagatttc
    11341 ttggcaggta aaatttcggc agatgctatt gaagagcttg gtgcgggagc acttcgcaat
    11401 gcagttgttg atggtgatgt aacaaatggc tccgtaatgg ctggtcaaat tgctggtcta
    11461 gtttctaaag aagaatcttg tgaagatatt ttgaaagata tctattatgg agcagccaaa
    11521 gtgattagag aagaggcaag ccgttgggct tcggttggag aataggatga caaagacagc
    11581 ttttcttttt gcaggtcaag ggtctcagac agtggggatg gctcgcgacc tttacgaata
    11641 ttacccgata gttagagaaa cgtttgacca ggctagtcag attctggggt atgacattcg
    11701 cgacctaatt gacaatcaag aggataaatt acatcagact cgctataccc aacctgctat
    11761 tttgaccact tctgtggcta tttttcgact gctggaagaa gagggaatac aacccgacat
    11821 ggtagctggt ctatccttgg gagaatattc agctctggtg gcatcgggag ctttggcctt
    11881 tgaagatgcg attgccctga ttgctaagcg tggtgaatat atggaactgg ctgcgccagc
    11941 agggactggt aagatggttg ctgttctcaa cacagatgtc aacttgattg aagaaatctg
    12001 tgcgactgtt acctctggga ttgtttcccc agccaactac aacacaccag cccaaatcgt
    12061 catcggaggc gaggtggctg cagtggatga ggcggttgaa ttgctgaagg aagcaggtgt
    12121 caagcggatg attccgctca atgtatctgg cccctttcac acggctctcc tgcgaccagc
    12181 gtcggagcaa ttggctcagg ccttggagca ggtggaactt gcggacttcc aagtagagtt
    12241 ggtcggtaat acggaagccg aggttatgaa aaaagaggac atcaagtccc tcttgccccg
    12301 tcaagtgatg gaaccagttc gtttctatga gtcaatcgca accatgcagg aagctggtgt
    12361 gactaacttt attgaaatcg gtccaggtaa agtcttatca ggatttgtca agaaaatcga
    12421 taagacggcg catgttgtag caattgaaga tatagagggg ctacaaatag tattaaacaa
    12481 atcatgagga ggaatcatgg aattaacaaa taaaaatgtt tttgtaacag gttcaagtcg
    12541 aggaatcggt ttggctattg ctcataaatt tgccagttta ggagcaaatg tcgttcttaa
    12601 tggtcgtggt cagctaggtc aggacttgct ggatagcttt gcagattacg gtgtgaaagt
    12661 cctagctatt tcaggagata tttcaagcgc gcaagatgcc aaacgaatgg tggcagaagc
    12721 catcgaaaca ctcggtagcg tcgatatttt ggtcaacaat gcagggatta ccaaagatgg
    12781 aatggctctt cgtatgacag aagaggattt tgatacggtt ctgaaggtaa atcttactgg
    12841 aacttttaat atgacgcagg ctgttttgaa accaatgaca aaggctcgtg agggtgctat
    12901 tatcaatcta tcaagtgtat ctggcttgat tggaaatgct ggacaggcca actattctgc
    12961 ttctaaggca ggtgtgattg gatttactaa agccattgcc cgtgaggttg ctgggcgaaa
    13021 tgttcgtgtc aatgcgattg cgccgggctt tatccaatct gatatgacag atgttttatc
    13081 tgacaagatt aaagaagcta tgactgcaca aattccgatg aaacgctttg gtgcgacaga
    13141 agaagtagct gatgttgcag tgtttcttgc caagcaagaa tatctaacag gacaggtgat
    13201 tgcggttgac ggcggcttga ccatgcagta agtttcctaa tgagaaagga ctgaaaatga
    13261 caaaattaaa tcgtgtagta gtaacaggct acggtctgac atctccaatc ggaaatacgc
    13321 cagaggagtt ctggaatagt ttgaaggctg ggaaaattgg gatcggaaag attaccaagt
    13381 ttgataccag tgaatattcg gtccataatg ctgcggaatt aaaagatttt ccttttgaca
    13441 aatatttcgt gaaaaaggat acaaatcgct acgataatta ctcgctctat gcactctatg
    13501 cagctaaaga agcgattgct aatgcacagc tggatacaga gacagtggat agtgaccgtt
    13561 ttggtgttat cttatcaaca ggtatcggtg gtattttgga aattgaagag caagttgctc
    13621 gtatgaatga aaaaggtcca aaacgcattc gtcccatggc tcttccaaag gccctgccaa
    13681 atatggcggc tggaaatatt gctatgcagg tcggtgcaaa tggcgtctgc aagtgcatca
    13741 tcacagcctg cgcttcatca aatgatgctt taggggaagc cttccgtgaa atcaagtttg
    13801 gtttccaaga tgtgatgctg gctggcggag cagaggcagc cattactccg tttgcaatcg
    13861 gtggtttcca agctttaaca gctatgtcga ctactgagga tccagaacgt gcgtctattc
    13921 catttgacaa ggaccgcaat ggttttgtca tgggagaggg ttccgcggtt ttagtattgg
    13981 aaagtttgga acacgcagag gcgcgtggag cgacgatttt ggcggaaatc gttggttatg
    14041 gaaatacttg cgatgcttac cacatgactt ctccgcatcc agaaggtctg ggtgctatta
    14101 aggccatgaa gttggccatt tcagaagcag gtttagagcc agctgatatt gactacatca
    14161 atgcccatgg cacttcgaca ccggctaatg aaaaagggga aagccaagct attgtatccg
    14221 tattcggcaa gaacacgcca gtttcttcca ccaagtcctt cacagggcac ttgttggggg
    14281 cggcgggtgc agttgaggcg gcagctgtca ttgaggctat gcgtcattct tatgcaccaa
    14341 agacagctgg tacgacagaa ttatctgaag atattgaagc ggatgtcatt tatggacagg
    14401 ggcgtgatat ggaaatccgt catgccattt caaatacatt tggctttggt gggcataatt
    14461 cagtcatcgc tttcaaacgt tgggaggcct aagtgaatat tacagaaatt aaggacctga
    14521 tgagtcagtt tgaccagtca agtttgcgag aattttcgta tagcaatgct ggggagatct
    14581 tgcatttcag taaaaaccag caggcgacag tggctccgag tccagcggta gaagctccgc
    14641 ttgccccagt aactcctgca agcccagccc ctgtgccagc agttgaaatg agtgagccag
    14701 ctccagcaga agcaggtgcc agccccgtgg cagaaggtgc ggtagtggaa agccccttgg
    14761 tcggcgtggc ttatttgtcc ccagcccctg acaagccagc ctttgtggca gttggggata
    14821 cggttaaaaa aggccagacc ctcatgatta tcgaagccat gaaggtcatg aacgaagtac
    14881 cagctgaccg tgacggtgtg gtcacagaga ttttggtggc caaccaagat gttgtagaat
    14941 ttggacaagg attggtacgc atcaaatgat tgatattttg aaaattaaag aggcgcttcc
    15001 tcatctctat cctatgctct tggtcgatcg tgtccttgaa gtatcggaag atgagattgt
    15061 tgccctcaaa aatgtgacca ttaatgagcc cttcttcaat gggcatttcc cagactatcc
    15121 tgtcatgcca ggtgttctca tcatggaggc tttggcacaa accgcaggtg tcttggagtt
    15181 atccaaggaa gaaaacaagg gcaagctggt cttttatgcc ggtatggaca aggttaaatt
    15241 taagaagcaa gttgtacctg gtgaccagtt aatcatgacc gctaaatttg tcaaacgccg
    15301 tggaaccatt gcggtcgttg aggcaaaggc agaggtggaa ggaaaactgg ctgcgtcggg
    15361 gacgttgact tttgctattg gaaaataata ctcttcgaaa atcaaactca gccgttgttg
    15421 acttgatttg atgagtgtca agctccagtg gagcttgaca gcctgctacc ataagataag
    15481 aaagtagcag gagtatatct gctcttggag aaacgaactt cgttcgctct atctccaacc
    15541 tccaaagctt tcccaaacct ttggagctag cctgattttg attttcattg agtatgaatc
    15601 ggtccgttat tttgcaaact agttaagggc tgagcttgtg ataaataatt attctatgtt
    15661 aaaaaggaga taggattcat catgtttgag aagattttga ttgctaatcg tggtgagatt
    15721 gcggtgcgga tcattcgttc ggccagagag ttggggattg cgacggtggc tgtctattca
    15781 gaggctgaca aggaagctct ccacaccatg ttggcagatg aggctgtctg tatcggccca
    15841 gcccgttcga cagactccta tctcaatatg caggcagtca tctcggcggc tgttgtgaca
    15901 ggtgcccagg ccattcatcc tggctttgga tttttgagtg aaaactccaa attcgccacc
    15961 ctctgtgaag aggttggtat caagttcatc ggaccttctg ggacggttat ggataccatg
    16021 ggcgataaaa tcaacgcgcg ggcggagatg gttaaggctc aagtgcctgt tattccaggc
    16081 tctgacggtg aagttttgac cagtcaagaa gcccttgaaa tcgctgaaaa gattggctac
    16141 cctgtcatgc tcaaggcatc ggcaggtggt ggcggtaagg ggattcgtaa ggtggaaaaa
    16201 gctgaagacc tagtgcctgc cttcgaatcg gcttccagcg aagccaaagc agcctttgat
    16261 aacggagcta tgtatataga gcgtgttgtc tatccagctc gccatatcga agtacagatt
    16321 ttggcggatc agcatggtca tgtcattcat ttgggagaac gggattgttc ccttcaacgc
    16381 aataaccaaa aagttttaga agaagctccg tcaattgcta tcggtcagac catgcgggaa
    16441 cgtatcggtc aagcagcagt gcgggctgcc cagtcagttg gatatgaaaa tgcaggaacc
    16501 attgagtttc ttttggacga agccaagggc gaattttact tcatggaaat gaacacacgg
    16561 gtgcaggtgg aacatcctgt taccgaattt gtcaccggtg tggacattgt caaggagcaa
    16621 atcaagattg cggctggtca ggaactcagt gtccgccaag aagatgtgaa gattactggt
    16681 catgccattg aatgccgcat caatgctgaa aatccagcct tcaacttcgc cccaagtcca
    16741 ggtaagattt ccactctcta cctgccaagt ggtggcgttg gtttgcgtgt agattcagct
    16801 gtttatccag gctacaccat tccgccttac tatgattcta tgattgccaa ggtcatcgtg
    16861 catggggaaa atcgttttga agccctgatg aagatgcagc gagccctcta cgaattggaa
    16921 attgacggag tggtgaccaa tacggacttc cagctggact tgatttccga caagcgagtg
    16981 gtggctggtg attatgacac tgcctacctc atggaagaat ttttaccccg ctatcaagaa
    17041 gatctaaaaa agtaaactag gagaatgcta tggctttgtt tcgcaaaaag gacaaatata
    17101 tccgcatcaa tcccaatcgt tcgcggatag agtcagcacc tcaagcaaag ccagaggtgc
    17161 cagatgaact cttttctaaa tgtcctgctt gtaaggtcat cctttacaag aatgatttag
    17221 gattagagaa aacctgtcaa cactgttcct ataattttcg gattacagcc caggaacgcc
    17281 gggctttgac agttgatgaa ggatcgtttg aggaattgtt tacagggatt gaaacaacta
    17341 atccgctgga cttccccaat tatttagaga aattagcagc cacccgtcaa aaaacgggct
    17401 tggatgaagc tgttttgaca ggcaaggcga caatcggcgg tcagccagtt gcccttggaa
    17461 tcatggattc tcactttatc atggcttcaa tgggcacagt ggtcggtgag aaaattaccc
    17521 gcctctttga gttggcgatt gaagagcgtt tgccagtcgt cctctttacc gcatctggcg
    17581 gtgctcggat gcaggaaggc atcatgagcc tgatgcaaat ggccaagatt tctgcagccg
    17641 tgaaacgcca ttccaatgct ggcctctttt acctgacggt cttgacagac cccacaacag
    17701 gaggtgtgac agctagtttt gccatggaag gcgatattat cctagctgag ccgcagacct
    17761 tggttggttt tgcaggacga cgggttattg agtcaaccgt tcgggaaaat ctgcctgacg
    17821 atttccagaa ggctgaattt ttacaggaac acggctttgt cgatgctatt gtcaaacgcc
    17881 aggacttgcc agcgaccatc agtcgcttgc tgagaatgca tggaggtgtc agatgaccag
    17941 tgatgtagca cgtatgatcc gtttggcacg tgaccaagct cgcctgacga ccttggacta
    18001 tgccacacaa ctctttgatg actttatcga attgcacggt gatcgcaatt tccgtgatga
    18061 cgaagctgta gtgggtggca tcggctttct agcaggtcag ccggtgacag ttatcggtat
    18121 ccaaaaaggg aagaaccttc aggacaacct caaacggaat ttcggtcagc cccacccaga
    18181 aggctaccgc aaggcccttc gccttatgaa gcaggcggaa aagtttggtc gccctgttgt
    18241 cacttttatc aataccgccg gagcctaccc aggcgtcggt gctgaggagc gtggacaggg
    18301 cgaggccatt gcccgcaacc tcatggagat gagtgacctc aaggtgccta ttatcgctat
    18361 tatcatcgga gagggcggct ctggtggagc tctggctcta gcggtggcag accaggtctg
    18421 gatgctggaa aactccatgt acgccgtcct cagccccgaa ggtttcgcct ctatcctctg
    18481 gaaagacggc agtcgagcca tggaagcggc agaactcatg aagatcactt cttatgagtt
    18541 ggagaaactc caagtggtcg atagggtggt tttggaaaat ggcagagcga ccaaggaagt
    18601 cttgtctgat atcaaggaca acctggtcag tcagttggct caactacaag ccttaccact
    18661 tgaacaacta ctcgaaaacc gctatcaacg ctttagaaaa tactaggaag acctagtatt
    18721 tttttgatag atttgataca atggataaaa taatttcagg aggttttcca tgttagtaaa
    18781 agcagatcta tcaaacgcag aagaattgct acctattcag caccgagcat ttgcggcttt
    18841 atataaaacc tatcaggacc agtacaaccc tgccattgaa actatggact atttccaatc
    18901 acgctttgca cgaccaaatt gtagctatta caagattatc gaggaagagc acacagtcgg
    18961 actagtacgg acaacggtcg ctgaagacgc tgaacagggc tggctaggct tgattggtat
    19021 tgatccagac cacagaggaa aaggctatgg tcacaaggct atgctcgaat tggaaagcct
    19081 ttatccgaca gttagacgct gggttctctg cacggttttg caggagtcta aattagtttc
    19141 tttctacgaa aagctcggct acaaggccat caaaacagag cctgaacaag aaggcatgga
    19201 tatggtctat atggagaagt ggataggaga ttcagatgct tgaacagtgt cgcagatacc
    19261 tggattatca aggagttcat tattgcaagc ctgaaaaagc aggagctttg gcaggcgata
    19321 tgatagcctt aaaaaatgta gcacaggcag cacgcaagga gtttcagaca ttaagtttag
    19381 tcttagctga gcacgtcagt ccctttgtgc ctgagagggt cagtcaatgg atgaatcaag
    19441 cccaaatttg cagaccacat ttttggacct attaccgttt tccctctgct agtctaacgg
    19501 actcggctct tgctattcgt ttgtatggta agggaactga agcagggatt tcagtagaag
    19561 tcagttttat tgaacgaaag aaagtggaga cctctctgct tcagcaaaat cgtgttctga
    19621 actgctcgat tgcggcaccg ctttattatt gggtgcaaga gggacaggta ttttatcgcc
    19681 tggacggaac ggaggagaat agacagagcc tattacaagc cgttgaagca ggacggattc
    19741 gtaaagtatt ggtcaagtat gatgtaccgt ttagaaccgt tgcctccgag gaggaactgc
    19801 tggaacgctt gattcagggc ttttctctac tagagcccta cttgaagatg acacacctcg
    19861 ctaaataatc agtggggtga tggcaacaaa catcgtaagg gtatttgttt tttagtgtat
    19921 attgacaaat tcattgaatt tttgtaaaac tgtatcacaa caacagaaca gtttgattga
    19981 cattacgtga aatcctataa tagattgaag gcactctata tgatgaagcg gaagaggaga
    20041 agagtatgga gaaactaggt caaagtttga aatggcttgg tcggaagatt tggctattat
    20101 taaggatttt tggtctctta gtgcttgctg tccttccgga tctgattttg gaagggtcca
    20161 aatcgcaagt caccttggta atagttgggc tgatgacact tggactttta gtctttttct
    20221 ggtggcgggc tgaaaaaatg atctgccagt ctgggaccct aacattctta cttgggacgg
    20281 tctggcgata gttatattag cctttgctat catgcagttg acggatatgc ttggttatta
    20341 tttgttggaa ttgcagggtg ttaccacaac agaaaacgat gcttcgatta tagaattttt
    20401 gaagggagtt ccttttagac tggcactctt gacaacagca tttttgccag cagttgtaga
    20461 agaagtcata tttcgaggct acttctttaa gaaattattt ggatcacagg ttttgttagg
    20521 aatagttgtt tcaagcctcg tttttggctc ctttcatggt ccaacagact taggctcttg
    20581 gttgattgat gctggcagtg gtattatttt gtctctcctc tattacaaga gtagatactt
    20641 aatctatcca ataatcgtac acttggtgaa caatttcatt gcaacagttt tttactatat
    20701 ataagaaaag acggttccat acggattcgt cttttgctat aagtagaaac atggaattta
    20761 acaaagtccg gagagtgacc gcataattaa atcaacatct tggttttcca actcacgaat
    20821 gatatgaaga taggttttct gggtcgttgt tatgcttgca tgaccaagtc gtctagcaac
    20881 acttgcgata gagaccccgg caaataataa aatagatgca tgggtgtgtc gcagggcgtg
    20941 aatggtgacg acaggaagat ttgcacttag gcaacgcttt tcaagaatgg cattgatggt
    21001 agagttgtaa atccgctctt tcttcacgaa aagtaggtca tcaggttggg tgtgctgtaa
    21061 taagttggcg aattgggtgc tggtttgcca gtcgagttgg atttttcgaa ttgaagattt
    21121 attttttgta ggtaaaaatc cgccgtctcc tttataattc catgttttat caatggtcaa
    21181 tagctgtcgg tgaaaatcaa aatcttgagt agtgagagca agggcttcgg agaatcgaat
    21241 acctgtttta gcaatcaata agatgagcca atcccaattc agctcctctc cgagacgtaa
    21301 ttcttgtatc aactgatgaa gttcaaattg gttgaggtat tttgtctttt tctttcgagg
    21361 aagtcttcct ttgataatca ccttacgtgt cggatctcgt tcaataattc cttcatctac
    21421 agcatctaaa atagctcctt tcaactggtg atgaaaatcc atggttgtct gtcgttcatg
    21481 tgttttagca tagctgttaa tcaattcttg gtaacgaacc cgattcaaat cttccaacaa
    21541 cagactagga gctagcctga taagccactg caatgtcatt ctatatttct tgagagtgac
    21601 ttctcgaatg gctccttcct tgtaaatccg aagccaattt gcataatagt gatggaaaag
    21661 caatttttct tttgataagt tcatggcaga acctcctttt ttaatttttg taaattacat
    21721 aatttattga caggtttctg agaagatgct atacttagtt tatcaaaaaa tgtaattatg
    21781 aaaaatttca aagaaaggga aattatgaaa ctagaagaat tggctctctt tatgggaggt
    21841 agtttacagg ttcgcttgga tactactagc tgggaagatg ctagagacta tatcctctac
    21901 aatcagcaac atcatcaatt ggatggttat gaggtgatag aagaagaagt gatagatagt
    21961 cggaccgtga cgacagatag agaagtgacc ttgctcgagg agggagactt actctttagt
    22021 ttactatcgg ggaaggctgt tttagtgaga gcggagcacg caggcttact ctatacacag
    22081 aactatatca aaattgagcc cattgcaaag ctggataagg ccttcttact gtatctgatc
    22141 aatgaatcct cggctattag acggcagttt taccaaagct tacaggggag tgaggtaatg
    22201 aaatatacag tcaagcaact gaaaagttta cagctaggtg ccttgcctcc tttagatagt
    22261 cagcagaaac taggaaagat ttatttagat ggattagcct tacggcagaa gcggcaagct
    22321 tatgcgcaag gagatttttt acgactaaca tatttgttaa aggaggttta ctcacatgaa
    22381 tgaattagca tttgaaacag aattgattca gtatattacg acagggacta ttacacaacc
    22441 ggagcaccta gaaggtttag aatggtctgt tagtgattct tcgaccttgt atgcagtcaa
    22501 atctaaactg tggacttatg agccgggtat caagacaacg gagcaattat gggaaaattt
    22561 tcgtaatatt ctctggcaac acaaccaaca tcgattggac aaacccttga gcgataccga
    22621 gtttgctcaa gtcaagcaga ttatttcaga tctgaagaca ccttatgagg ctggccagtt
    22681 tttatatgga attagcggtg tttccgaatt ggaaattacg cttgatgatg gacggcatac
    22741 atttttgaca gtattcgacc aacgtaagat aggcggtggg gacactgtct accaagtggt
    22801 gaaccaaatt cgtaggactc ctaaaatccc tggacgacga gaatgtatat tcgatacaac
    22861 cttgttgatt aatggcttac ctattattca gattgaagag aaaaaggata cggtagatgt
    22921 ggacaaggca ttgaaccaaa tgcaccaata tatccaggaa cggcaatata cggatatttt
    22981 ttctaccttg cagattctag tcgctatcgc ccccaacaat gttcgctata tggccaatac
    23041 cactgcggaa aaatttaata aggactttgc tttccactgg cagcgtaaat ctgacggtag
    23101 taaggttcgg aattggaaag actttgcgga ttccatgctc agcattccta tggcccatca
    23161 gatggcgacc aactacatga tcttagacgg gacaccgcag aaacaaatgc tgaaagtcat
    23221 gcgtccctat caagtttacg ccactcatgc ggtcattgag gggataaaaa aagtcgattt
    23281 tgaactaggc tgtaacaagg ttggctacat ctggcatacg acaggctcag ggaagacgat
    23341 cactagtttt aaaacagctt ggctggcaag tcgaatgccc aaggtagaca aggttgtctt
    23401 tctagtggat cgtatcgcat tgaccaatca gactaaggat gattatctgg cttatgatcc
    23461 agaagctggg gagaatagtt ttggcagtat tcgagaaact caaaatacca cagccttggc
    23521 acggcagttg actagtaagg atagtgggat tatcgttact tctgtgcaaa aattggatac
    23581 actggtgaag agaaaatcct tcaaatcacc agataagcat atcgtgttta tcgttgacga
    23641 agctcatcgc tcaactggtg gagatagttt tgcagggatt caaaaggcct ttaagaaagc
    23701 ggcttggatt ggctatacag gaactcccaa cttagatgat acaggtgcta gtctgcagac
    23761 gcaagatatt tttggccctc ttcttcatgc ctacactatt aaaaatgcca ttagtgaccg
    23821 caatgtacta gggtttaagg tagattttga gacaaccatc gatcaggaaa aactaaaaac
    23881 aacttactta ccagattttt atcggcaaaa atacccgaag tggacaagtg cacagattga
    23941 agaaaaaatt gccaatctaa gtccagatga tatggatgat gcggtgactt ctagcgtcta
    24001 tgatgaaaat ccagagcatg ttcgattggt agtcgaagat gtcttcaaac actgggcaaa
    24061 tcgctctggc agtggtcgtt acaatgcctt gttcaccacc cacgtaggtg gaggcagggc
    24121 ctccacaccc atggctatga tgtatttccg agagtttcaa cgaatcaatc aactacatcg
    24181 agagcaagga ggtctggtct tgaaggtggg attgaccttt gccttgaata ctcaaaataa
    24241 tgatagcatg gtcgagtcaa atactggttt gcttgaagct attacgatct ataacacaga
    24301 atttgggacg tcctttggct tgtcagatgt tgctgcgtat acagaggacc tgattagtcg
    24361 cctcaataga acagctcagg acaagaacta cttagatttg gtgattgtcg tggatcagtt
    24421 attgacaggt ttcaatgctc ctgagctcaa tactctttat gttgaccgaa cccttaaagg
    24481 agccagtctt attcaggcct attctcgtac caatcgtgtg gaggatatgg ataaaaaacc
    24541 ttttggacgg gtggtcaatt accgctggcc agctcataat gagaaattga tgaatcaggc
    24601 cttggccatc tatgcagatg atagtgctgc taatttatca gatgcggaac aaaaaaataa
    24661 caatgaaaaa aatggactgg tggctaagcc tttcaaggaa gtatttgctg aagtcaaaca
    24721 aacggtcgac caattgagag agttgacggg tgatttcaat gatattccga agtctgagaa
    24781 aaagcgtgag gctatgttag aattgctccg tgcttacaat caaggactgt ctaagctcaa
    24841 acagtatcag ccagaggagg ttgatggggt gattgaagga tttgattaca atcagccgga
    24901 ccgctttatt gaaagtttgg gaatgtctgt agaggaagaa aaacttttga cgacggtctt
    24961 agccaacgaa ttgaaacgaa ccttggcgaa agagcaaaaa gttagcattc accaaattga
    25021 actcaagatg actcacatca aggaagtgac aattgactac gataaattga ccgaactggt
    25081 tgagctcttg ctgaatcagg ttcacgaaga gaagatggta gaagccgcag ctaccaggga
    25141 tgaattggat agatttgcaa gcggtttgga agacctcaac tatgctgatc agatccgtca
    25201 aacaggggat gcaatctatc gaggtgattt tccgacacaa gatatgaact ttgcttatcc
    25261 agtcaagggg attgatagtc agaagattat ccaagaagct tcgcatgttt acattgacaa
    25321 gaagctcttt gctttccgaa tccaatgggg cttgacggaa catatccgca accaagaact
    25381 acgagagttg ttgacgagac atcgatatgg tcagaatgac ttggatgata ccggacactt
    25441 acgtaccttg ataaaagaag ctagtcgcga ttaccagacc tgggcagaag gtgatgctgt
    25501 taaaggcttg agcaagattc agtaccgcaa tcagttgaga caagcactat atgatttggc
    25561 cgacgacttg gttggtcaat aggttgcgat tttgttggat gatagcgtat aatagaatgg
    25621 aaatcgtccg aaaaattgca aaaataactt tcagaaatag aacaaaaaga gagtagaaaa
    25681 ggagggacta tgacaaaaga aaaatcaacc gtaccacgat tgcgcttccc cggattcacg
    25741 gacgcttgga aacagcgtaa gttgggggag gtggcggact tttccataaa aacaaactca
    25801 ctttctagag ataagttatc atcgtatttt tatgaagttc agaacattca ttatggggat
    25861 attttaacaa aatatgatgc tattttagat gtatgtaaca aagaacttcc atcaattatt
    25921 ggaagtacga tttcagactt tgcagatgct ttacttagtg aaggagatat tgttttcgcg
    25981 gatgcggcag aagactcgac tgttgggaaa gctattgaag ttcgaaattt taagggtaag
    26041 aatgttgttt ctggtttaca tacgatagtt gctaggccga aagtttctta tgccccctac
    26101 tatttaggtt atctaattaa ttcaactgca taccataatc aaattttacc tttaatgcag
    26161 gggacaaaag tgagctcaat tagtaaggct aatttaaaat ccacgacagt agtgttcccc
    26221 accctccctg aacaagaagc catcggcagc ttcttctccg acctagatca gcttattact
    26281 cttcatcagc gaaaattaga tgatgttaaa gaattgaaga aggctttgtt acagaaaatg
    26341 tttccgaaag ggaatggaaa cgattttcct gagctaagat tcccagaatt tacggacgct
    26401 tggaaacagc gtaagttggg ggagtttatg aaagaaagta aaattttagg tagtaaagga
    26461 gatatagcaa ggaagttaac tgtaagatta tgggggagag gagttgtttc caagaaagaa
    26521 atttatagtg gtagttcagc tacacagtat tatataagaa aatcaggcca gtttatatat
    26581 gggaaattag actttttaaa tcaagctttt ggaattattc caccagaact tgatggttat
    26641 gaatcaactc ttgattcgcc tgcttttgat ttattgaaag ggataaacgg gcaatttctg
    26701 ttagaatttg tatctcgcaa agaattttat tattatcaag gaa
//
LOCUS       DBNFCO010000024        26024 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.024, whole genome shotgun sequence.
ACCESSION   DBNFCO010000024 DBNFCO010000000
VERSION     DBNFCO010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 26024)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26024)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26024
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.024"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(14..1042)
                     /locus_tag="AC1PIV_000828"
     CDS             complement(14..1042)
                     /locus_tag="AC1PIV_000828"
                     /EC_number="2.7.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HIP6611865.1"
                     /translation="MQASSRSLRLMGTIIETKIWHPDAEPILDQVEELLYLYKDRFSA
                     NDLTSELMEVNLNAGVQAVPVADDLYELIKLGKEHSLAEGSFLNITIGPLVQSWRIGF
                     SDAKLPTQEMISEKLQLINPRDIELDDEEQTVYLKKEGMAIDLGALAKGYVADKIVDF
                     LKRIGVAAGLINLGGNVLTFGQAPHNADGYWRIGIQDPQKPRGENALVLKIGEESVVT
                     SGIYERTLTVNGKTYHHILSPETGYPMESQLASLTIVSKQSVDGEIWTTRLFGQEITR
                     IYKMVEETDGIEAVLIGLDGRILVTSGLSEKVLAGEERISDSLGSPSRGGFGARVTSD
                     LASGASVL"
     gene            complement(1029..1973)
                     /locus_tag="AC1PIV_000829"
     CDS             complement(1029..1973)
                     /locus_tag="AC1PIV_000829"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HIP6611866.1"
                     /translation="MTIYSKIIEKIHEYDTIIIHRHKRPDPDAIGSQVGLQKLLQKSF
                     PGKTIKVTGFEEPNLAWMAGMDEVADQDYQGALVIVTDTANTARVDDDRYAQGDFLIK
                     IDHHPNEEPYGDLLWVNTEASSCSEMITELAIQCQLELDGEIARLLYAGIVGDTGRFL
                     YPATSSRTFEIVARLRQEDFDFARMSRQMDTIDFKIAKLTGYVYDNLEVDEHGAARVI
                     LTQDILEKYGVTDADTSFIVGAPGRIGIVQSWGIFVKQTDGNYRVRLRSKYLPINEIA
                     KRHDGGGHPLASGANSYSLSENEQIYQEIQEVVRNASK"
     gene            2068..2529
                     /locus_tag="AC1PIV_000830"
     CDS             2068..2529
                     /locus_tag="AC1PIV_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HIP6611867.1"
                     /translation="MALAKIVYASMTGNTEEIADIVASKLEELGLEVQVHECTTIETE
                     EILDADLIVVASYTYSYGGDGELPDEIVDFYADLADLDLTGKVYGVCGSGDTFYDDFC
                     SAVDDFDVMLGSRGATKGAENVKVDLAAEDEDIVNLEQFATDLVAKLDTMN"
     gene            2670..2939
                     /gene="rpsN"
                     /locus_tag="AC1PIV_000831"
     CDS             2670..2939
                     /gene="rpsN"
                     /locus_tag="AC1PIV_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HIP6611868.1"
                     /translation="MAKKSKMARYQRQLELIERYADLRKSLKEKGDYQALRKLPRDSN
                     PNRLKYRDKTDGRPHAYMRKFGVSRITFRELAHLGQLPGVKKASW"
     gene            3021..3299
                     /locus_tag="AC1PIV_000832"
     CDS             3021..3299
                     /locus_tag="AC1PIV_000832"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HIP6611869.1"
                     /translation="MNLDCIREQINTIDSQLVELLEKRMELVDQVTAYKRATGKPVLD
                     TSRENAVLERVGKLVQKDDYRSAIQATFSDIMAQSRTYQSSKLANHEQ"
     gene            3289..4503
                     /locus_tag="AC1PIV_000833"
     CDS             3289..4503
                     /locus_tag="AC1PIV_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009910467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005247 - voltage-gated chloride channel
                     activity [Evidence IEA];
                     GO_process: GO:0006821 - chloride transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HIP6611870.1"
                     /translation="MSNKMKHAIQLLFFSSLIGVGAGIITTLFGKILLGIGDLRSEYF
                     TYLIPFLPLAGVLIVFIYQKWGREVQAGMGLVFKAGQGEKAQISPVLIPLIISTTWLS
                     HLVGASVGREGVAVQLGASLSHWLQKHGFTHLPKDMITKIGMAAGFAGLFQTPWAAGF
                     FAIEVLIVGQYSWTSLPYCLVAAFTASTTSHLLGLEKFSHTIATTSFYFTDSFKWLFI
                     ALCFGFIGNLFALFLAQAKSISTRWLPNPYIKIAIMGVGLTVLLFFFHQGRYTGLGTN
                     LIDASLAGEQVFAFDWLLKLLLTCLCLAAGFQGGEVTPLFAIGASSGAVLAGLLGLPT
                     ELVAALGYCAVFGTATNTLLAPLFISYEVFGANILPYAIPVLAIAYLINRKQTIYGQQ
                     LRKFNNAKKPII"
     gene            complement(4524..4595)
                     /locus_tag="AC1PIV_000834"
     tRNA            complement(4524..4595)
                     /locus_tag="AC1PIV_000834"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(4560..4562),aa:Arg,seq:cct)
     gene            complement(4791..6815)
                     /locus_tag="AC1PIV_000835"
     CDS             complement(4791..6815)
                     /locus_tag="AC1PIV_000835"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface-anchored 5'-nucleotidase"
                     /protein_id="HIP6611871.1"
                     /translation="MKKNIRLKSSILALVAGFSVIATQAVLADELAVQIMGVNDFHGA
                     LDMTGTARLEGETVRNAGTAALLDAYMDDSQAEFEETAAETETPAESIRVQAGDMVGA
                     SPSNSGLLQDEPTVKVFNKMDVEYGTLGNHEFDEGLDEYNRIMTGEAPKKGQFNEIVD
                     NYTREAAKQEIVIANVIDKETGEIPYGWKPYAIKTIPVNDKEAKIGFIGVVTTEIPNL
                     VLKKNYEQYTFLNEAETIAKYARELAEKGVNAIVVLAHVPATSKDGVAAGEAADMIAK
                     LNEIYPEHSVDLVFAGHNHVYTNGTTGKTLIVQATSQGKAYADVRAVYDTDIADFKAV
                     PTAKIIAVAPGQKTPSPEIQAIVDEANTIVKKVTEQKIATASQATDISREVNEFKESA
                     VGNLVTSAQLAIAKKSGYDVDFAMTNDGGIRADLKVQEDGTVTWGAAQAVQPFGNILQ
                     VVQMTGEQIYTALNQQYDEGEKYFLQMSGIKYIYTKADNPTEENPYKVVKAFKEDGTE
                     IVPTETYTLVINDFLFGGGDGFSIFKEAKLIGAINPDTEVFVEYLTDLEKAGQTISAT
                     IPGRKAFVEKYVEEPKAEEKEDNAGTTTDVKTPEKANDGGDSVTNQKATEQPAPSGSM
                     APISNKKTEKASGNQTLPNTGQEALGSLLISLGGLVSLGMAVSVRRKEGE"
     gene            complement(7077..7682)
                     /gene="sodA"
                     /locus_tag="AC1PIV_000836"
     CDS             complement(7077..7682)
                     /gene="sodA"
                     /locus_tag="AC1PIV_000836"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase SodA"
                     /protein_id="HIP6611872.1"
                     /translation="MTIILPDLPYAYDALEPHIDAETMTLHHDKHHATYVANANAALE
                     KHPEIGEDLVALLSDVEQIPSDIRQALINNGGGHLNHALFWELLSPEKTEISAELAAD
                     IDATFGSFDAFKEAFTAAATTRFGSGWAFLVVNKEGKLEVISTANQDTPIMQGLKPIL
                     ALDVWEHAYYLNYRNVRPNYIKAFFEVINWDKVNELYKAAK"
     gene            complement(7795..8826)
                     /gene="holA"
                     /locus_tag="AC1PIV_000837"
     CDS             complement(7795..8826)
                     /gene="holA"
                     /locus_tag="AC1PIV_000837"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HIP6611873.1"
                     /translation="MTVIEQIEKLKKEKLELLTVLCGEDIGQYQIAKDLLLRKLHFDA
                     ADLGFAYFDMSEADYHQVDLDLVSLPFFSDEKVVILDYFADLTTDKKRHLTDDELKQF
                     EAYLENPVETTRLVILAPGKLDSKRRLVKLLKRDGLVLEANPLKEMDLKNHFQKEIMR
                     LGLQMGGEVFQYLLEKSNFDFAEISKNLAFLQSYKGKETIEISDIDAAIPKTLQDNIF
                     DLTQLILQSKVDDARNLVCDLRLQGEEEVKLIAIMLTQFRTYLQVQILLEQGRGEQQI
                     VAELSTIMGRKVNPYQVKYALRDSRHLSIGFLKKVVKLLIDTDFQIKTGQFDKDYLFD
                     LLLLKIATT"
     gene            complement(8977..9567)
                     /locus_tag="AC1PIV_000838"
     CDS             complement(8977..9567)
                     /locus_tag="AC1PIV_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015445299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611874.1"
                     /translation="MKLRKVSFILVTFVIGLLSLSSVKAETSIFVPVGQQNVPGVKVA
                     PFRTGSDSIHVHVGSFGYVATYINGERLKVEPVKHELKCPSYTTENCQTREWYTSGER
                     ADGSGDYVVKLNKKLEEGDVVTLKFADDGNLYFGQLVYKSEKKRVEQNQKEQEDEYAD
                     ALFKRSIEEEENKTWRDRIKDTFQDTWWNFKGWWNS"
     gene            complement(9675..10430)
                     /locus_tag="AC1PIV_000839"
     CDS             complement(9675..10430)
                     /locus_tag="AC1PIV_000839"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0052693 - epoxyqueuosine reductase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HIP6611875.1"
                     /translation="MIKVEEILSTLSPNQKVNYDKVFQKMASTWQEAGLRPNILMHVC
                     CAPCSTYTLEYLTQYADVTIYFANSNIHPKAEYQRRAAVTAQFVKEFNQKTGQSVGYL
                     EADYSPQEFFKKTQHLANEPEGGDRCKVCYDYRLDKTAEKAVELGFDYFGSALTISPH
                     KNSQTINAVGIEVQKLYDTQYLPSDFKKNGGYQRSVQMCEEYDIYRQCYCGCVYGANA
                     QGVNLIQVKKEALEFLKTHRDYSHIPFKVLDKN"
     gene            complement(10860..11570)
                     /locus_tag="AC1PIV_000840"
     CDS             complement(10860..11570)
                     /locus_tag="AC1PIV_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIP6611876.1"
                     /translation="MAMLEVKNLSVNYGVIEAVKDVSFEVNEGEVVTLIGANGAGKTS
                     ILRTISGLVRPSAGTISFLGNEIQKVPARKIVADGLSQVPEGRHVFAGLTVMENLEMG
                     AFLHNNREENQANLRKIFARFPRLEERKNQDAATLSGGEQQMLAMGRALMSQPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAIADRGYVLETGKVVLSG
                     TGKELLASEEVKKAYLGG"
     gene            complement(11570..12334)
                     /locus_tag="AC1PIV_000841"
     CDS             complement(11570..12334)
                     /locus_tag="AC1PIV_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIP6611877.1"
                     /translation="MALLEVKDLTKNFGGLTAVGDVTMELHEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTISLAGTILNGKAPSKIASLGLGRTFQNIRLFKNMTVLENVLIG
                     LGNHGKSEVFASFFRLPAFYKNEEALKTKAIELLKIFDLDGDADTLAKNLPYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTQLIRKIKEEFGITIILIEHDMSLVMEV
                     TERIYVLEYGRLIAHGTPEEIRNNKRVIEAYLGGEA"
     gene            complement(12334..13281)
                     /locus_tag="AC1PIV_000842"
     CDS             complement(12334..13281)
                     /locus_tag="AC1PIV_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HIP6611878.1"
                     /translation="MKQNLKVNAIWLAILLAGFGLIQGLVSAGILNFYYIQIVQQIGI
                     QIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAVGILGKMMPTYGGFAIALIVGMLISG
                     AVALLVGIPTLRLKGDYLAIATLGVAEIIRILIINGGSVTNGAAGIMSIPLFTSWPLV
                     YIFVIITTLVTVNFLRSPMGRATISVREDEIAAESVGVNPTFVKVSAFVFGAMTAAIA
                     GGLHAGYVGTIVPKDFAFMTSVNVLIIIVLGGLGSITGTFVAAIVLGILNVFLKSYSD
                     ISMIIYSLALILLMIFRPGGLLGTKEFSVAALLKKKEVK"
     gene            complement(13284..14171)
                     /locus_tag="AC1PIV_000843"
     CDS             complement(13284..14171)
                     /locus_tag="AC1PIV_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HIP6611879.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDLYMMGA
                     FMGYFLLNNLTFIADGGTRFFVALILAMVGTAILGVVIEFLAYRPLRNSTRIAALITA
                     IGVSFFLEYTMIKFFTADVKAFPQAIEAVTFNLGPVSVTNIQLIILGVSLALMVALQL
                     IVKRTKMGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLLGLYYNQIE
                     PLMGMTPGLKAFVAAVLGGIGIIPGAALGGFVIGIIETFTYVIEFDTFRDAIVYTVLI
                     IILLVRPSGILGKNVKEKV"
     gene            complement(14387..15556)
                     /locus_tag="AC1PIV_000844"
     CDS             complement(14387..15556)
                     /locus_tag="AC1PIV_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HIP6611880.1"
                     /translation="MKTRKFAVALATFASAALLAACGNVSTTNTSAAGSSVGDTFKIG
                     YNLELSGAVSSYGQTEEKGANLAVKEINAAGGIDGKKIEVITKDNKSETAEAATVATS
                     LASEGANVVIGPATSGASAASIPALTSAGVPMITPSGTQTTLVVNDKGEVQEYFFRTT
                     FTDGYQGQIMAKYATENLSAKKVVLYFDNSSDYGKGVAEAFKKAYTGEIVSEITFASG
                     DKDFQAALTKLKDKEFDAIIMPGYYNETGTIVKQARGLGIDKPILGSDGFDSPQFTEL
                     ATASAASNVYYLSGFVTSASEKAKAFYDAYVKEYNEEPSMFSALAYDSVYMAAEAAKG
                     AADSAAVKANLAALKDFKGVTGTMSVDKEHNVIKSVYVVSLTNGEESSVDTISID"
     gene            complement(15687..15959)
                     /locus_tag="AC1PIV_000845"
     CDS             complement(15687..15959)
                     /locus_tag="AC1PIV_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HIP6611881.1"
                     /translation="MFEKKNRTCLTVYLHYNRDARKLSQYGDIVYHSKRLRYVLVYMD
                     QELVEATILKLKKERFVKKVVPSYIKELDQNFVGNLWRDEEPSVVG"
     gene            complement(16086..16697)
                     /locus_tag="AC1PIV_000846"
     CDS             complement(16086..16697)
                     /locus_tag="AC1PIV_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HIP6611882.1"
                     /translation="MSKRSNFMIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDN
                     MANSIIAQLLFLDAQDPTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGTAA
                     SMGTIIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNKLEKI
                     LADNSGKTVKQIHKDAERDYWMSAEETLAYGFIDQIMDNTKVK"
     gene            complement(16793..17422)
                     /gene="upp"
                     /locus_tag="AC1PIV_000847"
     CDS             complement(16793..17422)
                     /gene="upp"
                     /locus_tag="AC1PIV_000847"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HIP6611883.1"
                     /translation="MGKFQVISHPLIQHKLSILRRTSTSTKDFRELVNEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQIAGKKLAIVPILRAGVGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRHIFVVDPMLATGGSAILAVDSLKKRGASNIKFVAL
                     VSAPEGVKALQDAHPDIDIYTAALDEKLNEKGYIVPGLGDAGDRLFGTK"
     gene            complement(17502..19118)
                     /locus_tag="AC1PIV_000848"
     CDS             complement(17502..19118)
                     /locus_tag="AC1PIV_000848"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_function: GO:0004556 - alpha-amylase activity [Evidence
                     IEA];
                     GO_function: GO:0004574 - oligo-1,6-glucosidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009311 - oligosaccharide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HIP6611884.1"
                     /translation="MPEIQKTDWWKKSVIYQIYPRSFQDSNGDGVGDIRGIISRLDYL
                     HELGIDAIWLSPVYQSPMDDNGYDISDYQGIAPEFGTMEDMEELIAEGHKRNIKIIMD
                     LVLNHTSDEHFWFQEALKGPDNPYYDYYVWADEPNELRSTFSGSAWEYVPHLNKYYLH
                     QFSVKQPDLNWKNPALKQEIWDMINFWIEKGVGGFRLDVIDLIGKEPEKLITADGPTL
                     HPLIQELNEKTFGAYDLVTVGETWSANPENAQLYSHPDRKEFSMIFQFEHVGLDQQEG
                     KEKWDLAPLDPARLHKVLSKWQTELVGKGWNSLFWNNHDLPRAISRFGDDRPAFRELS
                     GKMLAIYLHFMSGTPYIYQGEEIGMINTPITDISQADDIETRRMYAERIENGFTKEEL
                     ITSINAKGRDNARRPMQWTEAEGAGFSTGQAWLALGDTVKDINVEKALADKQSLFYTY
                     QKLIALRKEYPCMSEGKYEVMETGNSSVMAYRKYDEQDDFIILVNFSSQEQAYTIAVE
                     EYSIFMNNYENEEAINKGMLRPFEAIVFKK"
     gene            complement(19191..20639)
                     /gene="gtfA"
                     /locus_tag="AC1PIV_000849"
     CDS             complement(19191..20639)
                     /gene="gtfA"
                     /locus_tag="AC1PIV_000849"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004645 - 1,4-alpha-oligoglucan
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HIP6611885.1"
                     /translation="MKIKNQAMLITYSDSLGKNLKDLKKVLEGPLKDVVGGIHILPFF
                     PSSGDRGFAPMDYTKVDPAFGDWSDIEALSKDYYLMFDFMINHISAKSPYFLDFLEKK
                     DESAYADLFIRYKNFWPNGEPTQEDVDLIYKRKPRAPYRIATFADGSEEKVWCTFDEQ
                     QIDLDVTTETTRRFIQENLEQLAEHGASIIRLDAFAYANKKIGTNCFFVEPDIWEMLH
                     FPRQLLAPKDVEILPEIHEHYTIQQKIAEQDYYVYDFALPMLVLHALYSGHVNRLVHW
                     MEICPRKQFTTLDTHDGIGVVDVKDLLTDEETEETREALYAQGANVKKIYSTEAYNNL
                     DIYQINCTYYSALGNNDQAYLLARVLQCFAPGIPQIYYVGLLAGENDIELLESSKEGR
                     NINRHYYDLEEIEQEVQRPVVQSLFKLLKFRNTSPAFDGEFSVKMLDETSMEIFWNNQ
                     DAGVSARLTANLKEKSFEIVEIEEGKITTIEL"
     gene            complement(20710..21540)
                     /locus_tag="AC1PIV_000850"
     CDS             complement(20710..21540)
                     /locus_tag="AC1PIV_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HIP6611886.1"
                     /translation="MNTQKQKNWWVYLVLFSGILFMFIPLLVTIISSFKPTKEITSNF
                     FGLPENFTLNNYERLFNDGIVQYFGNSALITIVAVGLILLVIPMAAFAVARQMKRQTV
                     FNFIYFFLIIGIFVPFQVIMLPMTKLMSSLGLNNIVGLIILYLTYAVPQALFLYVGYI
                     KTIVPEEMDEAAAIDGCDKFTMYWKIIFPLMKPMHATVLIINALWVWNDFLLPLLVLN
                     RDQSMWTLPLFQYNYQGMYFSDYGPSFASYVVGIIPILLVYLIFQKHIISGMTSGSVK
                     "
     gene            complement(21551..22423)
                     /locus_tag="AC1PIV_000851"
     CDS             complement(21551..22423)
                     /locus_tag="AC1PIV_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HIP6611887.1"
                     /translation="MNQKGFIAKYWPYLFVAIPIGLQLIFFFYPLFTGIYYSLTDWNG
                     LTSDFKLIGIQNYLDILKNPDFYTSMTFTIIFTIGLVIGEIVIGIWLASLLNRKIKAV
                     GFFRTWYFFPAVLSTVTLGLIFVQLFNYGFTQIGEILHIDWLMENLLVQENTVIPAVL
                     FVALWQGLAMPVIIFLSGLQSIPEDVKEAAAIDGASRSQQFFNIELPFLLPSISMVFI
                     LAMKSGLTAFDLIFALTSGGPDGKTESLGLLVYNYAFVDNKFSYANALAVVLFIFIIV
                     ISLIQMRISKKFEI"
     gene            complement(22558..23793)
                     /locus_tag="AC1PIV_000852"
     CDS             complement(22558..23793)
                     /locus_tag="AC1PIV_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HIP6611888.1"
                     /translation="MKMKTFLKCASVCAFASFLVACGNASSSDKVEIEYFSQKPEMQA
                     TLQEIIDDFEKENPTIDVKFSNVPDAGTVLKTRMANNEAPDVINIYPQNADFKAYAAD
                     GRFLEIGDDAGLNHLKDGAVTPYLVNEKNYTLPLTANAYGIYYNKDKFKELGLEVPTT
                     YAEFVALVDKIKADGSAAPFALSLNDAWSLNGYHQLAWVTVAGGFDGAEDILIRSAKG
                     AIQDDATTKAVLERLQLLKDNGQKGATGALYADAVAAFAAGDALMLPQGTWAATAVNQ
                     QEPEFEYGMFTFPGDKEGGDYTIGAADLALSISADTEHPEESKKFLEYLSRPEVIQKY
                     YDVDGSPTSVEGVDTEGKFEETAGVTQYAFTDKHVVWLQSEWESEEEFWNITVEMVKN
                     PNSAELVKKLNAFFDPMKK"
     gene            complement(23806..25980)
                     /locus_tag="AC1PIV_000853"
     CDS             complement(23806..25980)
                     /locus_tag="AC1PIV_000853"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_function: GO:0004557 - alpha-galactosidase activity
                     [Evidence IEA];
                     GO_process: GO:0016052 - carbohydrate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HIP6611889.1"
                     /translation="MNVIEIYNEKQIFHLKTREFSYIIQVLETGDLVHRYFGKKIEKF
                     SDGNKITYLDRSFSPSPITGDRTYSLDVLPLEYSSNGLGDFRTSALDVRNEFGVTLDL
                     KYKEYRLYKGKKELRGLPASFGNQEEVESLEIDLYDQLTDITVTLQYSVFEEASYLAR
                     SATIQTGKYPCKLEKVLSATLDFPHQDFIVHSLAGRYAYEKEWTQTPLTKGQYSIGSI
                     RGASSHSRTPFLALVSPDASEDKGDVYAAHLVYSGNFTAFVETTAMETSRLGLGLESH
                     YFSWQLDKDDRFQTPEVLLSYTDKGFTGMTQNSHHFITKHLIRSSFVNKPRPILINNW
                     EATYFEFTEEKILQLAQVASRAGIELFVLDDGWFGKRNNDESSLGDWKVNLDKLPNGL
                     NGLAERINELGMKFGLWFEPEMISIDSDLYREHPDWAIRTEGRLPIYSREQLVLDLTK
                     QEVCDYIIDSVSSILESANISYVKWDMNRNITNIPEGLANDQRFEFHHRYMLGLYRVL
                     DHLTKRFPDILFESCAGGGGRNDLGIMYYMPQAWASDDTDAIERLSIQEGTSLIYPPS
                     SIGAHVSAVPNHQVGRITPLATRGNVAMMGGAFGYELDLTKLSEKELDEISQQIETYH
                     SIRETIQFGQLYRLKKTSNTWAANYVSQDKNQVVFTFVKILAKPEAPLLHVRLKGLDP
                     DALYECPQLGETFYGDELMNIGLTMPHVQKDYFSVQYIFNKI"
BASE COUNT         7678 a         5679 c         4725 g         7942 t
ORIGIN      
        1 atattttttc aagttatagt acagaagcac ctgaagcaag gtcagaagtt actctggcgc
       61 caaatccccc tcttgaagga ctgcccaagc tatcagaaat tctttcttca ccagcaagaa
      121 ctttctcaga aagccctgag gtcactagaa tcctgccatc cagcccaatc agaaccgctt
      181 cgataccatc agtttcttct accatcttat aaatccgagt tatttcttga ccaaacagtc
      241 gagtcgtcca aatctcacca tcaacagatt gtttggacac aatggtcaaa ctagccagct
      301 gcgactccat tggatagccg gtctcaggac tcaaaatatg atgataggtc tttccattca
      361 cggtaagggt tctttcgtaa ataccagagg tgacaaccga ttcttctcct attttgagga
      421 cgagggcatt ttcaccacgt ggtttctgag gatcctgtat accaattcgc caataaccat
      481 ctgcattgtg aggagcttga ccaaaggtca ggacgttgcc acccagatta atcagcccag
      541 ctgccacacc tattcttttc aagaagtcaa caatcttatc tgctacatat cctttagcaa
      601 gagcacccag atcaatcgcc ataccttctt ttttcaaata gactgtctgc tcctcatcat
      661 ctaattcgat gtcccttgga ttgatgagct ggagtttttc actgatcatt tcttgggttg
      721 gaagtttggc atcgctaaat ccaatccgcc aactttgcac aaggggaccg atggtaatat
      781 tcaaaaaaga tccctcagcc agactgtgtt ctttgcccaa ttttatcaat tcatacaggt
      841 catcggcaac tggaactgct tgaacaccag cgtttagatt gacctccatc aattctgaag
      901 tcaaatcatt ggcagaaaac cggtctttat aaagataaag tagctcttcg acctgatcta
      961 aaattggttc tgcatctgga tgccatattt tcgtttcaat gatggttccc attagacgaa
     1021 gggaacggct acttgcttgc attcctcact acctcttgga tttcttggta tatttgctca
     1081 ttttcggata gtgaataaga gttagcacca cttgctagtg ggtggccacc gccatcatgg
     1141 cgtttggcaa tctcgttgat tggaagatac ttactgcgca aacggactct gtaatttccg
     1201 tcagtttgtt tcacaaaaat cccccaagat tgaacgattc caatccgtcc tggagcccca
     1261 acgataaagg aagtgtccgc atcggtcacc ccgtattttt cgagaatgtc ctgtgtcaaa
     1321 ataacacgcg ccgcaccatg ttcatccact tccaagttgt cgtagacgta acctgtcaac
     1381 ttggcaatct tgaaatcaat ggtatccatc tggcgagaca tccttgcaaa gtcaaaatct
     1441 tcttggcgga gacgagcaac aatctcaaag gtgcgcgagc tggttgccgg atagagaaag
     1501 cggcctgtat cgcccacaat tcctgcatag agtagacgag caatctctcc atcgagttcc
     1561 agttggcatt ggatggctag ttctgtaatc atttcactgc aagaactagc ttccgtattg
     1621 acccagagca ggtcaccata aggctcttca ttggggtgat gatcgatttt aatcaagaaa
     1681 tctccttgag catagcggtc gtcatccaca cgcgccgtat tggcagtgtc tgtcacgata
     1741 accaaagctc cttgataatc ttggtctgca acttcatcca ttcctgccat ccaagcaaga
     1801 tttggttcct caaaaccggt taccttgatg gtttttccag gaaaactctt ctgtaagagt
     1861 ttctgcaagc caacttgact accaatggca tccggatctg gtcgtttatg tcggtgaata
     1921 ataatcgtgt cgtattcgtg aattttttca ataattttac tgtaaattgt catagcaact
     1981 ccttttcatc attttagcat aaacttcccc ttttgaaaat gatgggagtg tggtataatg
     2041 gaattactat gtaatttgga ggaaattatg gcactagcaa aaatagttta cgctagtatg
     2101 actggtaaca cagaagaaat tgctgacatc gtcgccagta agctagaaga gttaggtttg
     2161 gaagtacagg ttcacgaatg tacgactatt gaaaccgaag aaatcttgga tgcggacctc
     2221 atcgtggtag ccagctacac ctattcttac ggtggagacg gtgagcttcc agatgaaatt
     2281 gttgatttct atgctgacct agctgactta gatttgaccg gtaaggtcta cggtgtttgt
     2341 ggttctggcg ataccttcta tgatgacttc tgtagtgcag tagacgactt cgatgtcatg
     2401 ttgggttcac gtggtgcaac taagggtgcc gaaaatgtta aggtagatct tgccgctgaa
     2461 gatgaggata ttgttaacct tgagcaattc gcgacagacc ttgttgctaa actagataca
     2521 atgaattaac tgacaaacag actggcttat caataggtct agtctgtttt cttttagcct
     2581 tttattaaga ttgtacacct attgcttgca atcttaatag ttttgatata taattaactg
     2641 gttaattttt ttgaaaaaag gagaatttta tggctaaaaa atcaaaaatg gcacgctatc
     2701 agagacaatt ggagttaatc gagcgctatg cggatttacg taaaagtctc aaagaaaaag
     2761 gtgactatca agcacttcga aaattgcctc gcgactcaaa tccaaatcga ctgaaatacc
     2821 gcgacaagac cgatggccgt ccgcatgctt atatgcgaaa attcggtgtg agtcggatta
     2881 ccttccgtga attagcccat cttggtcaac ttcctggggt aaaaaaagca agttggtaac
     2941 ttcctcaaac aaggctagta ttctgccttg ttttttgcta tactaaaaaa caactgaaac
     3001 aatatacgga ggtttataag atgaatttgg attgcatccg cgaacagatt aacacgattg
     3061 atagccaatt ggttgaacta cttgaaaaac gaatggagtt ggtcgaccaa gttacagcct
     3121 ataaacgagc aacaggtaag cctgttttgg ataccagccg agaaaatgct gtccttgaaa
     3181 gagtcggaaa attagttcaa aaggatgatt accgctctgc cattcaagca acctttagcg
     3241 atattatggc ccaatcaaga acctatcaat cttccaaatt agcgaatcat gagcaataag
     3301 atgaaacatg ccatccaact ccttttcttt tccagcttaa ttggagtcgg tgcaggaata
     3361 atcaccacac tttttgggaa aattctacta gggattggag acttacggtc tgaatatttt
     3421 acatatctaa tcccctttct gccacttgca ggtgtgttga ttgttttcat ttatcaaaaa
     3481 tgggggaggg aagtccaagc aggtatgggc ttagtcttca aagctggaca aggggagaaa
     3541 gcgcaaattt ctccagttct cattccactc atcatctcta caacttggct cagtcacctt
     3601 gtcggtgctt ccgttggtcg cgaaggtgta gctgtccaac ttggagccag tctctcacac
     3661 tggttacaaa aacatggttt cacacacttg cccaaagata tgataacaaa gattggtatg
     3721 gccgcaggtt ttgcagggtt atttcaaaca ccatgggctg ctggtttctt tgccattgaa
     3781 gttttaatcg ttggccaata ttcttggact agtctcccct attgtctagt tgccgctttc
     3841 acggcttcta ctacttccca tttactggga ttggagaaat tttcgcatac catcgctact
     3901 acctcattct attttacaga tagttttaaa tggctattta ttgccctttg cttcggtttc
     3961 atcggcaatt tatttgcttt gtttctggcg caagcaaaaa gcatctcaac tcgatggctt
     4021 ccaaatcctt acattaaaat agctatcatg ggagttggac tgaccgttct actatttttc
     4081 ttccatcaag gtcgttatac tggtctagga accaatttga tcgatgccag tttagctggg
     4141 gaacaggtgt ttgctttcga ttggctacta aaactcctac taacctgtct ttgtttggct
     4201 gcaggttttc aagggggcga agttactccg ctctttgcga ttggggcaag ttctggggct
     4261 gttttagcag gattactagg tctaccaact gaacttgttg cagcccttgg gtattgtgcc
     4321 gtatttggaa cagccaccaa taccttactg gctcctctct tcattagtta tgaagtcttc
     4381 ggcgctaata tcctgcccta tgctattcct gtacttgcca tagcttatct tataaacaga
     4441 aaacagacta tttatggaca gcagttgagg aaattcaata atgcaaaaaa gcctatcatc
     4501 taggcttttt cgtatactct tcatctcccc tgcaggaatc gaacctgcaa ctaattctta
     4561 ggaggaattt gttatatcca tttaactaag ggaagtctgc ttctctattg taccccagaa
     4621 gagagcagat tgcaagagca aggttatata agttttttca aatctttaca aaaagcagaa
     4681 cctactctaa gatgaaacac aattgttttt atgtatttct ctcataatag tctctaaaag
     4741 aagtaattct aaaatgtact tcgaaagttt gtcgttttta tgcttgattc ctactcccct
     4801 tccttacgtc tcactgagac agccattccg agtgaaacta agccacccaa gctaataaga
     4861 agtgagccta gggcttcttg accggtattt ggaagtgttt gatttcctga tgctttttca
     4921 gttttcttat ttgaaatagg agccatactt ccagatggtg ccggttgctc ggttgctttc
     4981 tgatttgtta cactatcgcc accgtcattt gctttctcag gtgttttcac atcagtagtt
     5041 gtcccagcat tatcttcttt ttcttctgct tttggttctt ctacgtactt ctctacaaat
     5101 gcttttctac ctggaattgt tgcactaatg gtttgacctg ctttttctaa atcagtcaag
     5161 tactccacaa atacttctgt atctggattg atagcaccaa tcagtttagc ttctttgaaa
     5221 atcgagaagc catccccacc accaaataag aagtcgttga tgacaagtgt ataggtttct
     5281 gtcggaacaa tctccgtccc atcttctttg aaggctttaa caaccttata aggattttct
     5341 tccgttggat tgtcagcctt cgtgtagata tatttaattc cagacatttg aaggaaatat
     5401 ttttcacctt catcatattg ttgatttaag gctgtataaa tctgctcacc tgtcatttga
     5461 acgacttgta ggatattccc aaatggttga acagcttgtg ctgctcccca agtaactgtt
     5521 ccatcttctt ggaccttcaa atctgcccga atcccgccat cgtttgtcat tgcaaagtca
     5581 acatcataac ccgatttctt agcgatagct aattgagccg atgttactag attacctaca
     5641 gcactttctt taaattcatt cacttcgcgt gaaatatctg tcgcttgact agctgtagca
     5701 attttttgct cagttacttt tttaacaatg gtatttgcct catctacaat tgcctgaatt
     5761 tccggacttg gtgttttctg ccctggtgct actgcaataa ttttcgcagt cggaacagct
     5821 ttaaagtcgg caatatctgt atcataaaca gccctaacat ctgcgtaagc cttaccttgt
     5881 gaggtagctt gaacaatcaa ggttttgccc gttgtaccgt ttgtatagac atggttatgg
     5941 ccagcaaata caaggtcaac tgagtgttca ggatagattt catttagctt agcaatcata
     6001 tctgcagctt caccagcagc cacaccatcc ttgcttgtag ccggaacgtg agccagtaca
     6061 actatcgcat ttacaccttt ttcagctaat tcacgcgcat atttagcaat cgtctctgcc
     6121 tcattcaaaa aagtgtactg ctcatagttt ttcttcaaaa caagattagg aatttctgtc
     6181 gtaactacac caataaagcc aatcttagct tctttatcat tcacgggaat agtcttaata
     6241 gcgtagggct tccaaccata cggaatttca cctgtttctt tgtcaataac gttagcaata
     6301 acaatctcct gtttagcagc ttcacgagta taattatcta caatctcatt aaactgacct
     6361 ttttttggag cttcaccagt catgatacgg ttatactcat caagtccctc atcaaactca
     6421 tggttcccca aagttccgta ttcaacatcc attttattaa agacttttac agttggttca
     6481 tcttgcaaaa gtccagaatt cgatggactt gcaccaacca tatccccagc ttgaacacgg
     6541 atagactctg caggtgtctc tgtttctgct gctgtttctt caaattctgc ttgtgaatca
     6601 tccatgtaag catcaagtaa agcggcagtt cctgcattac gaactgtttc cccttccaat
     6661 cgcgctgtcc ccgtcatatc aagcgcacca tggaaatcat taactcccat aatttggaca
     6721 gctaattcat ctgctaaaac agcttgtgtt gcaataacgc taaaaccagc tacaagagct
     6781 agtatactgc ttttcaaccg aatattcttt ttcataagca aaacaatgct ccttctattt
     6841 ttttcatatt gacatatcta taataatcct tttcttacgg cttttcaata tcaaatcagt
     6901 catttataac aaaaaattat aaaaatattc gtttattctt acttttacat catttttctg
     6961 aaaatatctt gtcattttta tctataatac gaaaattccc cttcttccct tacacaattc
     7021 tctccaaaat actcctcaca actaaaaaat ctcttccaaa cggaagagaa ctgttcttat
     7081 ttagctgctt tataaagttc gttaaccttg tcccagttga ttacttcaaa gaaggctttg
     7141 atgtagtttg gacggacatt gcggtagtta aggtagtaag catgttccca aacgtccaat
     7201 gccaagattg gtttcaaacc ttgcatgatt ggtgtgtctt ggttagcagt tgagataact
     7261 tccaacttgc cttctttatt aacaaccaag aaagcccaac ctgaaccgaa acgagttgtt
     7321 gctgctgcag tgaaggcttc tttgaaagca tcaaatgaac caaaggttgc atcaatatct
     7381 gctgccaatt ctgctgaaat ttctgttttt tcaggtgaaa gcaattccca gaaaagagca
     7441 tggttcaaat gaccaccacc gttgttgatc aaagcttggc ggatgtctga aggaatttgc
     7501 tccacatctg acaaaagagc taccaagtct tcgccaattt caggatgttt ttcaagtgct
     7561 gcattagcat ttgcaacata agtcgcatgg tgcttatcgt ggtgaagggt cattgtttct
     7621 gcatcaatat gtggttccaa ggcatcgtat gcgtatggaa ggtctggtaa aataattgtc
     7681 attttcgttt tctcctatac taagtgatag ttctattcta ctccaatgtg agagcctttt
     7741 caatttattt gtctgaaacc acggttgacc ctcaatctaa gaatactctt tttactatgt
     7801 agtcgcgatt tttaataata gcaaatcaaa taaataatcc ttatcaaatt ggccggtttt
     7861 aatttgaaaa tctgtatcga ttaggagctt gacgactttt ttcaaaaatc caatggacag
     7921 atggcgtgaa tcacgcaaag catactttac ttggtatgga ttcaccttac gccccataat
     7981 agttgataac tcagctacta tctgctgttc ccctcggcct tgctctagta gtatttgcac
     8041 ttgtagatag gttcgaaatt gggttaacat gatggcaatc aacttaacct cttcctcccc
     8101 ttgcaaccgc aagtcacaaa ctaagttgcg agcatcgtct accttggatt gtagaattaa
     8161 ctgtgttaaa tcaaagatat tatcttgtag tgtttttggg atagccgcat caatatctga
     8221 aatttcaatc gtctcttttc ccttataaga ttgaagaaag gctaggttct tactgatttc
     8281 tgcaaaatca aaattggact tttctaaaag atattgaaaa acctctcctc ccatctgcaa
     8341 tccaagacgc attatctcct tttggaaatg atttttcaaa tccatctcct tcagaggatt
     8401 ggcttctaat actagtccat ctcgtttgag gagtttgacc agacggcgct tactgtccaa
     8461 cttacccggt gctagaatga ccaaacgtgt tgtttcgaca ggattttcca aataggcctc
     8521 aaactgtttg agttcatcat ctgtcaaatg ccgtttttta tctgtcgtta aatctgcaaa
     8581 ataatcaaga atcactactt tttcatctga aaagaaggga agagaaacta ggtccaagtc
     8641 tacctgatga taatcagcct ccgacatatc aaaataggca aaacctaaat ctgccgcatc
     8701 aaaatgaagc ttccgcagaa gtaagtcttt cgctatttgg tattgtccga tgtcttcacc
     8761 gcataaaacg gtcagaagct ctaatttctc tttttttaat ttttcaatct gttcaattac
     8821 tgtcataaaa acctcaaaat tcttttctca ttgtaccaca aaaagagcct agacataaag
     8881 tctggactct ttcattgaaa tttatatcag gaaggtagga aaaaattaat tgataatcac
     8941 tccaaatgac ctatttccca aatagcagtt cctttgttag ctattccacc atcctttgaa
     9001 attccaccaa gtatcttgaa aagtatcctt tatccgatct ctccaagtct tattttcttc
     9061 ttcctcaata gaacgtttga acaaggcatc tgcgtactca tcctcttgtt ccttttgatt
     9121 ctgttcaact cgtttctttt cgcttttata tactaattga ccaaaataca aattcccatc
     9181 gtctgcaaat tttaatgtaa caacatcacc ttcttcgagt ttcttattca attttacaac
     9241 ataatctcca ctgccgtccg cacgttcccc acttgtatac cactctctag tttggcaatt
     9301 ctctgtagta taactcggac acttgagttc atgctttaca ggctcgacct tcaatcgttc
     9361 tccatttata tatgtagcga cataaccaaa tgagccaaca tggacatgaa tagagtctga
     9421 accagttcta aaaggagcta cttttacccc cggaacattc tgttgaccta ctggtacaaa
     9481 tattgaagtc tccgccttta cacttgataa cgatagtaaa ccgatgacaa aggtaactaa
     9541 aataaatgat acttttctca atttcatttt gcttttctcc tagtagtaca atacattaac
     9601 cggaattagt atataccaat ttcatagaga aagcaagaaa aaacgctcct taagtaaaaa
     9661 ctaaactcaa aaactcaatt cttatccagc accttgaaag gaatgtggga ataatctctg
     9721 tgcgttttta aaaattccaa ggcttctttt tttacctgta tgagattaac accttgggca
     9781 ttggctccat agacacagcc acaatagcac tggcgataaa tgtcatactc ttcacacatt
     9841 tgaactgaac gctgatagcc tccatttttc ttaaagtcac tcggaagata ctgggtatcg
     9901 tataatttct gcacctcaat cccaacagca ttgatggtct gcgaattctt atgtggactg
     9961 attgtcaaag ccgaaccaaa atagtcaaaa ccaagctcaa ctgccttctc cgcagtctta
    10021 tccaaccgat aatcatagca aaccttacac cgatctcctc cctctggctc attggcgaga
    10081 tgctgagttt tcttgaaaaa ttcctgaggg ctatagtcag cttctaggta gcctactgac
    10141 tgtccagttt tctgattaaa ttctttgaca aactgggccg tcacggctgc ccgccgctgg
    10201 tactccgcct ttggatgaat attggaattc gcaaaataga tggttacatc tgcatattga
    10261 gtcaagtact ccaatgtata ggtcgagcat ggggcacaac agacatgcat gagaatgttc
    10321 ggtcgaagcc ccgcttcctg ccacgtgctt gccatttttt gaaacacttt atcatagtta
    10381 accttttgat tcggtgatag agtcgataaa atctcttcaa ctttaatcat acaaacctcc
    10441 aaatatacat tcattatact atatttgaag cctactgcat agatagtaat aacgagggag
    10501 agcgcttgat aaggatccct atttccaact taaaaaggtc cctcggacct tgatataaag
    10561 aaaaacgcct gccgacgttt ctcatctcca gcttaaaacg tggggtaacc cacttgtaaa
    10621 gaaaaccgct taccagcggt tctcatttcc aacctaaaac aacccgtcag gttggggaca
    10681 aaccagcaac atgcattgct ggttttccta tctcccgatt aaaacagcct atccgaatat
    10741 aaaaaaactg cctgccggca gttctcattt tcaacttaaa acgtggggta acccacttat
    10801 aaagaaaacc gcttaccagc ggttctcatt tccaacctaa aaaggtcccc cggacctttt
    10861 tagccaccca gatatgcttt tttgacttct tctgaggcga ggagttcttt tcctgttcct
    10921 gagaggacaa cttttcctgt ttctagaaca tagccacgat cggcaatagc gagagctttg
    10981 ttggcatttt gctcaatcaa gaggacagtt gttccttgtt tttgaatatc ttggatgata
    11041 tcaaaaattt cttggataaa gatcggagcc aagcccattg atggttcatc aaggagcaag
    11101 agctttggtt ggctcattag ggcacgtccc atggccaaca tctgttgctc cccacctgaa
    11161 agggtagctg catcctggtt tttacgttct tccaaacgtg gaaaacgagc aaagattttt
    11221 ctcaagtttg cttggttttc ttcacgattg ttgtgaagga aggcacccat ttccaagttt
    11281 tccataacag tcaagcctgc aaaaacatga cgaccttctg gaacttgtga taaaccgtcc
    11341 gccacgattt tacgagcagg aactttttga atctcatttc caaggaaaga aatcgttcca
    11401 gctgatggac gaacaagccc tgaaatagta cgaaggatag aggttttacc agcaccatta
    11461 gcgccgataa gggttacaac ttcaccttca ttaacctcaa agctaacatc tttaacagct
    11521 tcgataacac cgtagttaac ggaaagattt tttacttcta acattgccat taagcttcac
    11581 ctccaaggta ggcttcaatt acacgcttgt tattacgaat ttcttctggt gtaccatggg
    11641 caatcaaacg accgtactcc aatacgtata tccgctccgt cacttccata accaagctca
    11701 tatcgtgttc aatcaagatg atagtaatgc caaattcttc tttgatttta cggatgagtt
    11761 gggtcaattc tgccgtttct tgtgggttca taccagccgc tggctcatcc aagaaaagaa
    11821 ttttcggttc agtcgcaagg gcacgaacga tttccaaacg tcgttgttga ccgtaaggaa
    11881 ggtttttagc taatgtatct gcatctccat ccaaatcgaa gattttcaaa agttcaatcg
    11941 cttttgtttt caacgcttct tcattcttat agaatgctgg aagacggaag aaacttgcaa
    12001 atacttctga tttaccatgg ttgccaagac caatcaaaac attttccaaa acggtcatat
    12061 ttttgaacaa acgaatgttc tggaaagtac gacctagacc aagcgaagca atttttgatg
    12121 gtgctttacc gttcaaaata gtccctgcca gagaaattgt cccctcgctt ggctcataaa
    12181 cacctgttaa gaggttgaaa agagtcgttt taccagcacc gtttggaccg ataagaccaa
    12241 ccaattcccc ttcatgaagt tccatggtca cgtcaccaac ggcagtcagg ccaccgaagt
    12301 tcttggttaa atcttttact tcaagtaatg ccattactta acctccttct tcttgagtag
    12361 agccgctacg ctgaattcct tagttcccaa aagacctcca ggacggaaaa tcatcaagag
    12421 aataagagct aatgaataga taatcattga aatatcagag taactcttga ggaatacgtt
    12481 caaaatacca agtacaatgg ctgctacaaa ggtacctgtg atagagccca aaccacccaa
    12541 tacaatgata atcaaaacgt taacagaggt cataaaggca aagtctttcg gaacaattgt
    12601 cccaacgtat cctgcatgga gaccacctgc aatggctgcc gtcatggcac caaatacaaa
    12661 ggctgaaacc ttaacaaatg ttggattgac acctacagat tctgccgcaa tttcatcctc
    12721 acgaacagaa attgtagcac gtcccatcgg actgcgcaaa aagttaactg tcaccaaggt
    12781 tgtgatgatt acaaaaatat aaactaaagg ccagcttgta aagagtggta tagacataat
    12841 acctgctgca ccattcgtta cactaccacc attgataatt aaaatacgaa taatctctgc
    12901 aacaccaaga gtcgcaattg caaggtagtc acctttcaaa cgaagggttg gaataccgac
    12961 taaaagagct actgcacctg agattaacat cccaacaatc aaggcgatag caaatccacc
    13021 ataagtcggc atcattttcc caagaatacc tactgcataa gcaccaatag ccataaaacc
    13081 agcatgacca agtgaaaatt gacctgagaa accgacaatc aagtttaaac caactgccaa
    13141 gataatttga ataccgattt gctgaacaat ctggatgtag taaaaattca gaatccctgc
    13201 tgatacaaga ccttgaataa gtccaaaacc agccaataag atagccaacc aaatcgcatt
    13261 aacttttaaa ttttgcttca tggttacacc ttctctttca catttttacc aagaatacca
    13321 cttggacgca ccaagaggat gatgatcaaa acagtatata cgatcgcatc gcggaaagta
    13381 tcgaattcaa tcacataggt gaatgtttcg atgataccga taacgaagcc accaagcgct
    13441 gcacctggaa taataccgat accgcccaat actgccgcaa caaaggcttt cagacctggc
    13501 gtcatcccca tcaaaggctc aatctggttg tagtagagac ctaggagaac acccgcagca
    13561 cccgcaagag ctgacccaag agcaaaagta aagctgattg tacggtttac attgatcccc
    13621 ataagctgag ctgcatcgct atctacagag accgcacgca tggctttccc catttttgta
    13681 cgtttgacaa ttaattgaag tgcaaccatc aacgcaagcg atacaccaag aataatcaac
    13741 tggatattcg taacagaaac tggaccaagg ttaaaagtca cagcttcgat tgcttgtgga
    13801 aaggctttta cgtctgctgt aaagaattta atcatagtgt attctaagaa gaaggataca
    13861 ccgatagccg taatcaaagc tgctatacgc gttgaattac gcaaaggacg ataggctaaa
    13921 aactctataa ctacaccgag aatagccgtc cctaccatcg ctagaatgag agcaacaaag
    13981 aaacgcgttc caccatctgc aataaaagtt aaattattta ataggaagta ccccataaaa
    14041 gcacccatca tatacaaatc accatgggcg aagttaatga gtttgataat tccgtacacc
    14101 atggtataac caagggccaa aagggcataa acagaaccaa gaatcaaacc attgacaagt
    14161 tgttgaagca taggttcacc aatctttcta aatatttttc gagctcaata gcattgttac
    14221 attatacaaa attttctgaa aataagcaag ttagacagag agtttaatca ttaaaattac
    14281 agaaaattta accaacccaa atttaaccaa attttatatc cgcatgtata ctattctata
    14341 cattctgaca agtgaaaaag agggaattcc ctcttttcat ccactattag tcaatagaga
    14401 tagtatctac agatgattct tctccgtttg ttaaactaac aacataaact gatttaatga
    14461 cattgtgctc tttgtcaaca gacattgtac cagtcacacc tttaaagtct ttcagagctg
    14521 caagattagc cttcactgct gctgaatcag ctgcaccttt tgctgcttct gctgccatgt
    14581 aaaccgagtc gtaagctaaa gctgagaaca ttgatggctc ttcattgtat tctttcacat
    14641 aggcatcata gaatgctttt gctttttcgc ttgctgatgt tacaaatcca gaaaggtagt
    14701 aaacatttga tgctgctgat gcagttgcca attcagtaaa ttgtggtgag tcaaaaccat
    14761 ctgaaccaag aattggcttg tcaataccca aaccgcgtgc ttgcttcaca attgtacctg
    14821 tttcattgta gtaaccaggc atgatgatcg catcaaattc cttatctttc aattttgtca
    14881 aagcagcttg gaaatcttta tcgccagaag caaatgtgat ttctgaaacg atttctcctg
    14941 tgtatgcttt cttgaacgcc tctgctacac ccttaccata atcagaagag ttgtcaaagt
    15001 aaagaacaac tttcttagct gacaagttct cagtagcgta tttagccata atttgacctt
    15061 gatacccatc tgtaaaggtt gtacggaaga agtattcttg gacctcacct ttatcgttca
    15121 caaccaaggt tgtttgagtt cctgaaggag taatcatagg aacaccagca gatgtcaatg
    15181 ctggaataga ggctgctgaa gctcctgatg tagcagggcc aatcacaacg tttgcccctt
    15241 cacttgccaa gcttgttgca acagtagctg cctctgctgt ttcagacttg ttgtcttttg
    15301 tgatcacttc gatttttttg ccgtcaatac cacctgcagc attgatttct ttcacggcaa
    15361 ggttggcacc tttttcctct gtttgaccat aagatgaaac agcacctgac aactccaagt
    15421 tgtagccgat tttaaatgta tcacctacag aagaacctgc ggctgaagta ttggttgtcg
    15481 aaacattacc acatgcagcg agtagagctg cagaggcaaa tgtagcaagc gctactgcaa
    15541 attttcttgt tttcatgaaa actccttaaa tctttcttaa attttacgat gtatctaata
    15601 tactgaatta tctgaaaatt gtcaacaaaa aagaaaaaaa ttttaaaata aaaaattagc
    15661 agggaataca tacctgctaa ttccgactat cctacgactg atggttcttc atctctccat
    15721 agattaccta caaagttttg gtctaattcc ttaatgtatg aaggaaccac tttttttaca
    15781 aaacgttcct ttttcaattt taatatggta gcttctacta gttcttgatc catatacacc
    15841 aaaacatatc gcaagcgttt ggaatggtaa acaatatctc catattggct gagtttacgt
    15901 gcatcacgat tgtagtgtaa atagacagtt aagcaagtgc gatttttctt ctcaaacatg
    15961 tcttctcctc taaaaattct ctttctatat tataccgttt tcaatgataa atgaaaagct
    16021 ccaactacct gtaaaagagt tggagctaat aggaatagtc agtactatta catatttgtc
    16081 actgcttatt tgacttttgt attgtccata atctggtcaa taaatccgta agccaaggtt
    16141 tcttcagctg acatccagta atcacgttcc gcatccttgt ggatttgctt gactgtctta
    16201 cctgagttgt ctgccaagat tttttctagc ttattacgtg tttttaatag gtgttctgca
    16261 gcaatagcca tatctgtttg ctgagtacca ccaccagttc cacccattgg ctggtgaatc
    16321 atgtactctg catttggcaa catgaaacgt ttgcccttgg caccgcttga tgcaatgatg
    16381 gttcccatgc tcgcagctgt tcccataacg atggtttgaa catcagcttt aatgaaattc
    16441 atcgtgtcta caatggcaag acctgctgac accgatcctc ctggcgtatt aacatagagg
    16501 taaatatcct ttgtagggtc ttgggcatca aggaaaagca attgtgcaat gatagagttt
    16561 gccatgttgt cctcaactgg tcctgtcaac atgataatac ggtctttcaa aaggcgtgag
    16621 taaatatcat aagaacgctc accacggcta gtttgttcaa taactactgg aatcataaaa
    16681 ttactccttt tcgagatttt ctgtacccat tatatataaa tagtcaaaat tggtcaaata
    16741 aaaaacacga tttcaggaaa tgaaaaagaa accagcagag ctgatttctt aattattttg
    16801 taccgaacaa gcggtcacct gcatctccca aacctggtac gatgtagcct ttttcattga
    16861 gtttttcatc caaagctgct gtataaatat caatgtctgg atgtgcatct tgaagagctt
    16921 ttacaccttc tggagctgaa acaagagcaa caaatttgat atttgaagca ccacgttttt
    16981 tcaatgaatc aactgcaaga atagctgaac cacctgtagc aagcattgga tcaactacaa
    17041 aaatatgacg ttgatcaatg tcttctggta atttcacaag atactcaacg ggttgaaggg
    17101 tttcttcatc gcggtacata ccgatgtgac caactttagc tgctggtacc aagcttagca
    17161 aaccatcaac cataccaaca cctgcacgaa gaattggtac gatagctaat tttttacctg
    17221 caatttgttt ctgaactgtt ttagtgattg gcgtttcaat ctccacatct tcaagtggca
    17281 agtcacgcaa aacttcgtaa cccatcagca tcgcgatttc attaaccaac tcacgaaaat
    17341 cctttgttga agtagatgta cgacgaagga tagacaactt atgctgaatg agtgggtgtg
    17401 aaatgacttg gaatttcccc atgatgataa aacctctctt ttttgttttt tctattttac
    17461 caaaaaaatt gaaaaaatgc ttgagaatat ggcaaattta tttatttttt gaaaacgata
    17521 gcttcaaaag gtctcaacat ccctttatta atcgcctctt cgttttcata attgttcatg
    17581 aaaatagaat attcttccac agctatagta taagcctgtt cctggcttga aaagtttacc
    17641 aatatgatga aatcatcctg ttcatcatat ttacggtagg ccattaccga gctatttcca
    17701 gtctccatca cttcatattt tccttcagac atacaaggat actctttccg aagagcaatt
    17761 aatttttgat aggtataaaa aagtgattgt ttgtctgcaa gtgctttttc aacattgatg
    17821 tctttgacag tatctcccaa agccagccag gcttgacctg tactgaagcc tgctccttct
    17881 gcctctgtcc attgcattgg acgacgagca ttatctcgac ctttggcatt tatagaagta
    17941 atcaattcct ccttggtgaa gccattttca atccgttccg catacatgcg acgtgtttca
    18001 atatcgtccg cttggctaat atctgtaatt ggcgtattaa tcataccaat ttcctcacct
    18061 tggtagatat aaggtgtccc tgacataaaa tgaagataga tagccaacat tttaccactt
    18121 agttcacgaa atgcaggtcg atcatcaccg aagcgagaaa tggcacgagg taaatcgtgg
    18181 ttattccaga aaagcgagtt ccagccttta ccaaccagtt cagtctgcca tttggagaga
    18241 accttatgca aacgtgctgg atcaagcggt gccaaatccc acttttcttt cccttcctgc
    18301 tgatcaagtc cgacatgttc aaattggaaa atcatcgaaa attcttttct gtcagggtgt
    18361 gaatataact gagcattttc tggattggca ctccatgtct ccccaacagt cactaagtcg
    18421 taagcaccaa aggttttctc atttaattcc tgaataagag gatgaagagt cggtccatcg
    18481 gctgtaatta atttttctgg ttcttttcca atcaaatcaa tcacatctag cctgaaaccg
    18541 ccgacacctt tttcaatcca aaaattgatc atgtcccaga tttcttgttt cagagcagga
    18601 tttttccagt tcagatctgg ttgcttaaca gagaattggt ggagatagta tttgttcaga
    18661 tgtggaacgt attcccaagc agagcctgag aaggtcgagc gtaattcatt cggttcatca
    18721 gcccaaacat aataatcata atagggatta tctggtcctt tgagggcttc ttgaaaccag
    18781 aagtgttcat ccgaggtatg attgagcact aaatccatga ttattttgat attgcgctta
    18841 tggccttctg caatcagctc ttccatatct tccatggtcc caaattctgg agcaattcct
    18901 tggtagtcac tgatgtcgta accattgtca tccatggggg actgataaac aggactgagc
    18961 caaatagcat caattccaag ctcatggaga taatctaatc ggctgataat ccctcgaata
    19021 tcccctactc catctccatt tgaatcttga aaactacgag gataaatttg gtaaatgacg
    19081 gacttcttcc accaatctgt tttttgtatt tctggcattt gattgatcct ttctgtacaa
    19141 tcttattaat gtaagaaaaa gaggtgtccc cctctttcta tataatcata ttataactca
    19201 attgtggtaa tttttccctc ttcaatttca acaatttcaa aggatttttc ttttaggttt
    19261 gctgttagac gggcagacac ccctgcatct tgattattcc agaaaatttc catacttgtt
    19321 tcatccaaca tcttaacaga gaactccccg tcgaaagctg gacttgtatt gcggaattta
    19381 aggagtttga acaaggattg tacaactggc cgttgcactt cctgctcaat ttcttccaaa
    19441 tcatagtaat ggcgattgat attgcgccct tccttacttg attctaaaag ttcaatatca
    19501 ttttcgcctg ctagtaaacc aacataataa atctgtggaa tacctggtgc aaagcattgg
    19561 agaacacgcg ccaatagata agcttgatca ttattgccaa gagcagaata ataagtacag
    19621 ttaatctgat aaatatccaa attattatag gcttctgtac tataaatttt cttcacattg
    19681 gcaccttgtg catacaaggc ttcacgggtc tcctctgtct cctcatccgt cagcaaatcc
    19741 ttaacatcca caacaccgat tccatcatgt gtatcaagag ttgtaaattg cttgcgaggg
    19801 caaatctcca tccagtgaac caggcgattg acatgaccag aatacaaagc gtggagaact
    19861 agcattggca aggcaaaatc ataaacataa taatcttgct cggcaatttt ctgctgaatg
    19921 gtgtagtgtt catgaatttc tggtaagatt tctacatctt ttggtgccaa taactgacgt
    19981 ggaaaatgga gcatttccca aatatcaggc tccacaaaga aacaattggt tccgattttt
    20041 ttattggcat aagcaaaggc gtccaaacga ataatcgaag caccatgctc tgccaactgt
    20101 tccaaatttt cttggatgaa acgacgggtt gtctccgttg tcacatctaa atcaatctgc
    20161 tgttcatcaa aggtacacca caccttctct tcactaccat cagcaaatgt tgcaattcga
    20221 taaggtgcgc gaggtttacg cttataaatc aaatcaacat cttcttgcgt tggctcacca
    20281 tttggccaaa agtttttata acgaataaac aaatccgcat aagctgattc atctttcttt
    20341 tcaagaaaat caaggaaata aggagatttt gctgaaatat gattgatcat aaaatcaaac
    20401 atgaggtaat agtctttgct tagtgcttca atatctgacc aatctccaaa tgcagggtcc
    20461 acctttgtat aatccattgg cgcaaaccca cggtcacctg atgatgggaa aaacggcaga
    20521 atatggatac ctcccacaac atcctttaac ggcccctcaa gaactttttt caaatcctta
    20581 agattcttgc ctaaactatc cgaataggta attaacatag cttgattttt aattttcata
    20641 gactttctcc tttgtaagcc ttttcttttt tgttatttta taaaaggttg aactagtcaa
    20701 ccttagtaat tatttgacag aaccacttgt catacctgaa ataatatgtt tttggaagat
    20761 gaggtaaaca agtaagattg ggataattcc tacaacatag gatgcaaatg atgggccata
    20821 gtcactaaaa tacatacctt ggtagttgta ttggaaaaga ggtaaagtcc acatgctttg
    20881 atcacggttc aatactagca aaggcaagag gaaatcattc cagacccaga gggcattgat
    20941 aatcaaaaca gttgcatgca tgggtttcat gagtgggaaa atgattttcc agtacatggt
    21001 aaatttatca cagccatcaa tagctgccgc ttcatccatt tcttcaggaa caatggtctt
    21061 aatatagccg acgtagagga agagggcctg aggaactgca taggtcaaat atagaataat
    21121 caaaccgaca atattgttca aaccaaggct tgacattaat ttggtcattg ggagcataat
    21181 cacttggaaa ggtacaaaaa tcccaataat caagaaaaag tagataaagt taaacactgt
    21241 ctggcgtttc atttgacggg ctacggcgaa agctgccatt ggaataacaa gtagaatcaa
    21301 gccaacagct acaatcgtaa tcaaggcaga attgccaaaa tattgtacaa ttccatcatt
    21361 aaacaagcgt tcgtagttat ttaaggtgaa attttcagga agaccaaaga aattgctggt
    21421 aatttccttg gttggtttga atgagctgat aatggtcacg agtagcggaa taaacatgaa
    21481 caatatccca ctaaagagaa ctaagtaaac ccaccaattt ttctgttttt gagtattcat
    21541 gtctgtcctc ctaaatttca aatttcttcg aaattctcat ctgaatcaat gagatgacaa
    21601 taatgaagat gaagagtact acagccaaag cattggcata agagaatttg ttgtctacaa
    21661 aggcatagtt gtaaacgagt aaacccaagg attctgtttt gccgtctggg ccaccacttg
    21721 tcagtgcaaa gataaggtca aatgctgtca aacctgactt cattgccaag atgaaaacca
    21781 tactgataga tggtaataag aatggaagct caatgttgaa gaactgttga gaacgacttg
    21841 caccatcaat agctgctgct tccttcacat cttctggaat actttgtaag ccagacagga
    21901 agatgatgac tggcatagcc aatccttgcc agagagccac aaaaagtaca gctggaataa
    21961 cagtattttc ttgtaccaat aagttttcca tcaaccaatc gatatgaagg atttctccaa
    22021 tctgtgtaaa accatagttg aacaattgga caaaaatcaa tcctaaagtg actgtggata
    22081 gcactgctgg gaagaaatac caagttctaa agaaaccaac tgctttaatc ttacgattga
    22141 ggagactagc caaccaaatc cctataacaa tttctccgat gaccaaacca atggtgaaga
    22201 taatggtaaa agtcatggaa gtataaaaat caggattttt taaaatatct aagtaattct
    22261 gaataccgat tagtttgaaa tcagatgtca atccattcca atccgtcaag ctataataga
    22321 tacctgtaaa tagaggatag aagaaaaaga ttaactgtaa gccaattggt atggcaacaa
    22381 atagataggg ccaatatttg gcaataaatc ctttttgatt catcatggta ctcctttttg
    22441 ataaagttat agttgcttag tctcagttca aggaatccca tagggttact aaaactgaca
    22501 ctaggcaact ataaggaggc taggctacaa ctagcccctg cttatagttt tcctggatta
    22561 ttttttcatt ggatcaaaga atgcgttcag ttttttcact aattctgctg agttaggatt
    22621 tttaaccatt tcaacagtga tgttccagaa ctcctcttct gattcccatt cagattgcaa
    22681 ccaaactacg tgtttgtcag tgaaggcata ttgtgtcact ccagcagttt cttcaaactt
    22741 accttctgta tctacacctt caactgaagt tggtgagcca tctacatcat agtatttctg
    22801 gataacttct ggacgagaga ggtattctag gaatttttta gactcttctg ggtgctctgt
    22861 atctgctgaa atagatagtg caagatcagc tgcaccgatg gtatagtcgc caccttcttt
    22921 atcaccaggg aatgtaaaca taccatattc aaattctggt tcttgttggt ttacagctgt
    22981 agctgcccat gtaccttgtg gaagcatgag agcatcaccc gctgcaaagg ctgccaccgc
    23041 atctgcatag agcgcgcctg tcgccccttt ttgtccattg tctttcaaca attgcaagcg
    23101 ttctaaaact gcttttgttg tagcatcatc ttgaatcgct ccctttgcac tacgaatcag
    23161 aatatcttct gcaccatcaa atccacccgc aacagttacc caagctaact gatggtagcc
    23221 gttcaatgac caagcatcgt tcaatgaaag agcaaacggt gctgcactgc catcagcctt
    23281 gattttgtct accaaagcca caaattctgc ataggtagtt ggaacttcga gccccaattc
    23341 tttgaactta tccttattat agtaaattcc gtaggcatta gctgtcaaag gaagggtata
    23401 atttttttcg ttaacaagat atggtgttac agcaccatct ttcaaatgat ttaatcctgc
    23461 atcatcacca atttctagga aacgaccatc cgctgcgtat gctttgaagt ccgcattttg
    23521 tggataaatg ttgatgacat ctggcgcttc gttatttgcc atacgggttt tcagaacagt
    23581 tcctgcatct ggtacatttg aaaatttaac atcaatcgta ggattttcct tttcgaaatc
    23641 atcaataatt tcctgaaggg tagcttgcat ttctggtttt tgtgaaaaat attctatttc
    23701 taccttatcg ctactacttg cattcccaca agcaaccaaa aagctggcaa aagcacaaac
    23761 cgatgcacat tttaaaaatg ttttcatttt cattataaaa tcctcctaga ttttgttaaa
    23821 aatatattgt acactaaaat aatctttttg aacatgtggc attgtaagac caatgttcat
    23881 cagttcatcc ccgtagaatg tctctcctaa ttgtgggcat tcatacaagg catctgggtc
    23941 taaccccttc aaccgaacat gaagcaaagg cgcttctggc ttggcaagaa tttttacaaa
    24001 tgtaaagacc acttgattct tatcttgact aacataattg gcagcccagg tattgctcgt
    24061 ctttttcaga cggtagagct gaccgaattg tatagtttca cgaatggagt gataggtttc
    24121 gatttgctga ctgatttcat ccaattcctt ttccgaaagt ttcgttaaat ccagctcgta
    24181 accaaatgct cctcccatca tagccacatt gcctcgtgta gcaagaggtg tgatccgacc
    24241 aacctgatgg tttggaacgg cagaaacgtg tgcaccaatt gaggaagggg gataaatcaa
    24301 actagtacct tcttgaatag ataagcgctc aatcgcatct gtatcatcac ttgcccaagc
    24361 ttgcggcata taatacatga ttcccaaatc attacgacct ccaccgcctg cacaggattc
    24421 gaaaagaata tccgggaacc gctttgtaag gtggtctaat acacggtaga gacctagcat
    24481 gtaacgatgg tggaactcaa agcgctggtc atttgctaaa ccttcaggaa tattggtgat
    24541 attacggttc atatcccatt ttacataaga aatattggct gattctaata tggaagagac
    24601 gctatcaatg atgtagtcac agacttcctg cttggtcaaa tccaaaacta attgttctcg
    24661 gctgtagatt ggtaagcgtc cttctgtccg aattgcccaa tcaggatgct cacgataaag
    24721 atcgctatca atagaaatca tctctggttc aaaccacaat ccgaatttca taccaagctc
    24781 atttattcgc tctgctaaac cattcaaacc atttggcaac ttatccaaat tgactttcca
    24841 atcgcccaat gaactttcat cattgtttcg tttaccaaac caaccatcat ccagaacaaa
    24901 caattcaata ccagctcgac ttgcaacctg agctaactgt aaaatctttt cttctgtaaa
    24961 ttcaaaatag gtcgcttccc agttgttgat taaaatgggt cttggtttgt ttacaaacga
    25021 tgatcgaatg aggtgttttg tgataaagtg atgactattt tgtgtcatgc cagtaaatcc
    25081 tttatcagta tatgataaga gaacttctgg agtttgaaac cggtcatcct tatccaattg
    25141 ccatgagaaa tagtgacttt ccaatcctag tcccaaacga ctggtttcca tggctgtcgt
    25201 ttcgacaaat gctgtaaagt tgccgctata aacaaggtgg gctgcataaa catcgccctt
    25261 gtcctcactt gcatcgggtg aaactagtgc taaaaagggt gttcttgagt gacttgaagc
    25321 acctcgaatg ctaccaatcg aatactgacc ttttgtcaat ggggtctgtg tccactcttt
    25381 ttcataagca taacgtcctg ccaagctgtg aacaatgaaa tcctgatgtg gaaaatcaag
    25441 cgttgcagac aagaccttct ctagtttgca tggatatttg ccagtttgaa ttgtagctga
    25501 ccgtgcgaga taggaagctt cttcaaaaac agaatactga agagttacgg taatatctgt
    25561 caactgatcg taaagatcaa tttcaagact ctctacctct tcttgatttc caaaacttgc
    25621 tggtaatccc ctcagttctt ttttcccctt gtataatcga tactctttgt attttaggtc
    25681 aagagtgact ccaaattcat tccgaacatc taatgctgag gttctaaaat ctcccagacc
    25741 attgctggaa tattcgagtg ggaggacatc caatgagtat gtcctatccc cagtaattgg
    25801 actcggagaa aacgatcgat ctaaatatgt tattttgttt ccatcgctaa atttttcgat
    25861 ttttttccca aaataacgat gaaccagatc gcctgtttcc aatacttgga tgatataaga
    25921 gaattctctt gttttcaggt gaaaaatctg tttttcatta taaatctcaa tcacattcat
    25981 ctctcctatc tcttctttat ggtcttattg tacaaaatga aaac
//
LOCUS       DBNFCO010000025        25540 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.025, whole genome shotgun sequence.
ACCESSION   DBNFCO010000025 DBNFCO010000000
VERSION     DBNFCO010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 25540)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25540)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25540
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.025"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            155..1360
                     /gene="rpsA"
                     /locus_tag="AC1PIV_000854"
     CDS             155..1360
                     /gene="rpsA"
                     /locus_tag="AC1PIV_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HIP6611890.1"
                     /translation="MNEFEDLLNSVSEVTPGDVVTAEVLTVDAGQANVAISGTGVEGV
                     LTLRELTNDRDADINDLVKVGETLELLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKVTRAVKGGLAVEFEGLRGFIPASMIDSRFTRNTERFVGQEFDAKIKE
                     VDPAENRFILSRRDVVEAAAAAARAEVFGKLAVGEVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSAVTVGEEVEVKVLAIDEVEGRVSLSLKATQPGPWDGVEQKL
                     VAGDVIEGKVKRLTDFGAFVEVLPGIDGLVHISQISHKRVENPKDALSVGQEVTVKVL
                     EVNAADERVSLSIKALEERPAAVEGEEKAEKRAPRPRRQKREEKRDYELPETQSGFSM
                     ADLFGDIEL"
     gene            1398..1469
                     /locus_tag="AC1PIV_000855"
     tRNA            1398..1469
                     /locus_tag="AC1PIV_000855"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1431..1433,aa:Arg,seq:ccg)
     gene            1531..2559
                     /locus_tag="AC1PIV_000856"
     CDS             1531..2559
                     /locus_tag="AC1PIV_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016503195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004793 - threonine aldolase activity
                     [Evidence IEA];
                     GO_process: GO:0006567 - threonine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine aldolase family protein"
                     /protein_id="HIP6611891.1"
                     /translation="MLHFENDYNKGAHPALLEALVASNQEGLSGYGTDKYTESAIEKI
                     RLATDCPHAQVTFLAGGTQTNQIVISSMLASYEGVIAADTGHIAVHEAGAIEFTGHKV
                     LALPHTDGKLVASEVENYISDFYADANHAHMVHPGMVYISHPTEYGTLYSKSELEALS
                     TVCRHHNIPLFLDGARLGYGLAARDTDLDLKTIAELTDVFYIGGTKLGALMGEALVFT
                     KNNQPKNFVSIVKHHSALLAKGRVTGIQFDCLFTDDLYLELGRHAIAMAEQLTQILEE
                     KGFQFYLKSPTNQQFVIVKNEELTRLTEVGIAYGFWEKYDDSHSIIRFATSWSTSQAD
                     IDALRNRL"
     gene            complement(2578..2961)
                     /locus_tag="AC1PIV_000857"
     CDS             complement(2578..2961)
                     /locus_tag="AC1PIV_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611892.1"
                     /translation="MKYVILKTPIFVWLLIFALIQIFALSSFLPEPFDTRSLLPMGVL
                     TGCSIRVSSEVKDQDGQYAPFKYLWWVILGWTVIGILFGITIKAPLELHIALIVHAIA
                     GGIGYRLIERYAVYRYHYLQTKKKG"
     gene            complement(3022..3435)
                     /locus_tag="AC1PIV_000858"
     CDS             complement(3022..3435)
                     /locus_tag="AC1PIV_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6556 family protein"
                     /protein_id="HIP6611893.1"
                     /translation="MNTRKNTNKKPAGLTNFQKYLTFIGSILGIITACITIYTFTAKP
                     ATSSTSPSTTISSSSATSPSQSSSDNPLTEVQDSTSSSSETTSSTQTETSSLVESTVS
                     SSSTETSATQALETRTETSTDTEVTSGASETTSNQ"
     gene            3548..4690
                     /locus_tag="AC1PIV_000859"
     CDS             3548..4690
                     /locus_tag="AC1PIV_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018543459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HIP6611894.1"
                     /translation="MIYFDNAATTQVYPEVLKTYTEVATKIWGNPSSLHSLGSQATRI
                     LEASRKQIAELLGQDSKEIFFTSGGTEGDNWVIKGVAFEKAHLGKHIIVSAIEHPAVK
                     ESALWLKTQGFEVDLAPVNAQGFVDVSALESLIRPDTTLVSIMAVNNEIGAIQPIQEI
                     SQLLADKPTISFHVDAVQAIGKVPTERYLTDRVDFASFSGHKFHSVRGVGFVYIKAGK
                     KIAPLLTGGGQESDKRSTTENVAGIAATAKALRLTLDKAADSQKRLAAMKQILVDELG
                     KYDDVTVFSGLEDFVPSIVTFGIKNIRGEVIVHAFEDHQIYISTTSACSSKAGKPAGT
                     LIAMGVPQKLAQTAVRISLDDDNDMGQIEQFLTIFKQIYQNTQKVR"
     gene            4692..5909
                     /gene="thiI"
                     /locus_tag="AC1PIV_000860"
     CDS             4692..5909
                     /gene="thiI"
                     /locus_tag="AC1PIV_000860"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140741 - tRNA-uracil-4 sulfurtransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uracil 4-sulfurtransferase ThiI"
                     /protein_id="HIP6611895.1"
                     /translation="MNYSEIMIRYGELSTKGKNKMRFVNKLRNNIKHVLSVYPEVTVY
                     FDRDRGHVYLNGADYQEVSASLKKIFGIQNFAPSYKIEKSVPALKEAVVEIMQTIYKE
                     GMTFKIAARRSDHSFELDSRDLNQVLGDAVFTAIPNVQVQMKSPDITLRVEIRPDAAY
                     ISHEEIKGAGGLPVGTSGKGTLMLSGGIDSPVAGYLALKRGVEIEALHFASPPYTSPG
                     ALKKAHDLTRKLTAFGGNITFIEVPFTEIQEEIKEKAPEAYLMTLTRRFMMRITDRVR
                     EERGAMVIINGESLGQVASQTLESMQAINAVTNTPVIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNVEQYEARMDVEGLVERAVAGIIVTEITPKEE
                     VKDEVDSLIEDLL"
     gene            6028..7356
                     /gene="brnQ"
                     /locus_tag="AC1PIV_000861"
     CDS             6028..7356
                     /gene="brnQ"
                     /locus_tag="AC1PIV_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HIP6611896.1"
                     /translation="MMKKGALTGLLLFGMFFGAGNLIFPPALGVLSGENFWPAILGFV
                     VSGVGIAVIALIVGTLNPKGYVHEISRKISPTFATIYLVALYLAIGPFFAIPRTATTS
                     FEIGIAPLLGDANLGLWLFGFTALYFVAAYLIALNPSQILNSIGRILTPVFAILIVIL
                     VVLGIVKYGSTSPLPASEAYSAGQAFGTGFIEGYNTLDALASIAFSVVAVNTLKQLGF
                     SSKREYVSTIWSVGLVVALAFSALYVGLAFLGNHFPVPADVLASDTNKGVYILSQATQ
                     AIFGPGAQIFLAAMVIVTCFTTTAGLIVSSGEFFAERFPRFSYKVYATIFTLIGFGIA
                     NLGLNNIITFSVPVLLVLYPITICIVLITIVNKFVPLSTYGMQLTVGLVTALSLVEVL
                     AGQFNWTAVSKIISALPLAGQSLAWLLPALVGIVLSLFLPNKQESEVFEM"
     misc_feature    7423..7511
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            7547..7861
                     /gene="rplU"
                     /locus_tag="AC1PIV_000862"
     CDS             7547..7861
                     /gene="rplU"
                     /locus_tag="AC1PIV_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HIP6611897.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAIYVEKLNVEAGQEVTFEEVVLVG
                     GEKTVVGTPLVAGATVVGTVEKQGKQKKVVTFKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     gene            7908..8201
                     /gene="rpmA"
                     /locus_tag="AC1PIV_000863"
     CDS             7908..8201
                     /gene="rpmA"
                     /locus_tag="AC1PIV_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HIP6611898.1"
                     /translation="MLNLNLANLQFMAHKKGGGSTSNGRDSQAKRLGAKAADGQTVSG
                     GSILYRQRGTKIYPGANVGRGGDDTLYAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            8393..8551
                     /locus_tag="AC1PIV_000864"
     CDS             8393..8551
                     /locus_tag="AC1PIV_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIP6611899.1"
                     /translation="MFRGSGMGSNLVKLVIDDLANRNSKAFQIAVEEEKLGTWKLYKK
                     LVLKNRTG"
     gene            8634..9548
                     /locus_tag="AC1PIV_000865"
     CDS             8634..9548
                     /locus_tag="AC1PIV_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HIP6611900.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISIRDLEKELG
                     FQIFSRTSSGTFLTQKGMEFYEKAQALVKGFDQFEHLYLQPEEGEKTFSISSQHYDFL
                     PPLITEFSRSHPQYPHFRIFESTTVQILDEVAQGYSELGIIYLNERNTKGIMQKLDKL
                     HLQAVDLSAFQTHIYLREDHPLTKKAEIDPVDLVGLPTVRFTQEKEAYLYYSENLIDT
                     SDSSVVFDVTDRATLNGILERTDAYATGSGYLDDESVNGITVIPLKGKVDNRMVYVKR
                     ANDELSSCAKDFIETMQAYFDKKKDENA"
     gene            9541..10005
                     /gene="lspA"
                     /locus_tag="AC1PIV_000866"
     CDS             9541..10005
                     /gene="lspA"
                     /locus_tag="AC1PIV_000866"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HIP6611901.1"
                     /translation="MRKIGFPFLMVVLIGLDQFVKAWTVANIELDTVTEFIPGLMSLA
                     YLRNYGAAWSILQNQQWFFTIMTIVAVTGLVWYYIKQIKGNIWTLFSLSLMIAGALGN
                     FIDRLRLGYVVDMFHLDFISFPVFNVADVCLTVGVGILFICIMKEESNGSKS"
     gene            9989..10882
                     /locus_tag="AC1PIV_000867"
     CDS             9989..10882
                     /locus_tag="AC1PIV_000867"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HIP6611902.1"
                     /translation="MEVRVEVGGIRLDKALSDLTDLSRSVANEQIKAGQVLVNGQPKK
                     AKYSVQVGDVLTYQIPEVEEIDYVAEDIPLEIVFQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALLYHVKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHTKLAAELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKEAVTRFQVLERFGDYTLV
                     ELTLETGRTHQIRVHMAYIGHPVAGDEAYGPRKTLKGHGQFLHARTLGFTHPRTGEVV
                     EFTAEAPAIFQEALEKLRKAE"
     gene            10963..11301
                     /locus_tag="AC1PIV_000868"
     CDS             10963..11301
                     /locus_tag="AC1PIV_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein YjdM"
                     /protein_id="HIP6611903.1"
                     /translation="METLPNCPKCNSEYVYEDGALLVCPECAYEWNPADVAEEESGPV
                     AIDANGNRLADGDTVTLIKDLKVKGAPKDLKQGTRVKGIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVKKI"
     gene            11349..11996
                     /locus_tag="AC1PIV_000869"
     CDS             11349..11996
                     /locus_tag="AC1PIV_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HIP6611904.1"
                     /translation="MKHQSILFYSRCLLAILAITGTALEIIKYCIGMLMYYTVQSNLL
                     VSLFAVYMVYAMSKGVDLQTSRFLRIKAAVTMSIMITCVVYHFMLAPLADDFWRLENL
                     LCHYIVPLYFLLDTLIVDRQQQYKWFDPIWWTLLPVLYMIFGLVNGLFIKIPIPDAKD
                     SPFAYFFLNVPKYGWTYVLTYAGVIFVAYLVCGFLLAGLKSINLKTSLSFGKNSQ"
     gene            12195..12716
                     /gene="pyrR"
                     /locus_tag="AC1PIV_000870"
     CDS             12195..12716
                     /gene="pyrR"
                     /locus_tag="AC1PIV_000870"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HIP6611905.1"
                     /translation="MKTKEIVDDMTMKRAITRITYEIIERNKNLDNIVLAGIKTRGVF
                     IAKRIQERLKQLEGIDVPLGELDTKPFRDDMKVEDDTTNMTANVNDRDVILVDDVLYT
                     GRTIRAAIDNIVSLGRPARVSLAVLVDRGHRELPIRADYVGKNIPTSRSEEIIVHMAE
                     IDGQDAVLLVEGA"
     gene            12772..13695
                     /locus_tag="AC1PIV_000871"
     CDS             12772..13695
                     /locus_tag="AC1PIV_000871"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002889464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0016597 - amino acid binding [Evidence
                     IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HIP6611906.1"
                     /translation="MTITNGKVSLKHLVTMETLSNEEVLGLIQRGIAFKRGEKVELDR
                     KYYASNLFFEDSTRTHKSFEMAELRLDMGMIDFDARTSSVNKGETLCDTILTMSALGV
                     DICVIRHSEVDYYKQLIDSPTIQTSIVNGGDGSGQHPSQSLLDLMTIYEEFGTFDGLK
                     IAIAGDITHSRVAKSNMQILKRLGAEIFFAGPEEWYAEEFDVYGQHLNIDDIVETVDV
                     LMLLRVQHERHDGDGGFSKETYNRLHGLTEERYKRLKDTAIVMHPAPVNRDVEIDDSL
                     VEAPKSRIVRQMQNGVFVRMAILEAIVNGKA"
     gene            13943..15022
                     /locus_tag="AC1PIV_000872"
     CDS             13943..15022
                     /locus_tag="AC1PIV_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl phosphate synthase small subunit"
                     /protein_id="HIP6611907.1"
                     /translation="MSKRRLILENGTIFEGEAFGADIDVTGELVFSTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDFESIKPTCKGVVVSEWARRASNWRNQMTLDEFLK
                     AKKIPAISGIDTRALTKIIRQHGTMKATLANVGDSVEHLTDQLRATILPTNNIQQVST
                     KTAYPAPGVGRSVVLVDFGLKHSILRELAKRDCNVTVVPYDTTAEEILALNPDGVMLS
                     NGPGNPDDVPEALDMIRGILGKIPIFGICMGHQLFAKANGATTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVAREDLPECLMITHEEINDKSVEGVRHKYYPGFSVQFHPDA
                     APGPHDASYLFDEFMELMDSFKKGQ"
     gene            15382..18561
                     /gene="carB"
                     /locus_tag="AC1PIV_000873"
     CDS             15382..18561
                     /gene="carB"
                     /locus_tag="AC1PIV_000873"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HIP6611908.1"
                     /translation="MPKRTDIKKIMVIGSGPIVIGQAAEFDYAGTQACLALKEEGYSV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDAFLPTLGGQTGLNMAMEL
                     SKAGILDELGVELLGTKLSAIDQAEDRDLFKQLMEDLNQPIPESTIVTTVDEALEFAA
                     EIGYPVIVRPAFTLGGTGGGMCANEEELREIAENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDAADNALVVCNMENFDPVGIHTGDSIVFAPTQTLSDIENQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEM
                     VNPVTGTTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVYHNEMPELSQVTDDQLVEKIVKAQDDRLFYLSEALRRGYTVEELAQ
                     LTKIDLFFLDKLLHILEIEQELATNFDNIDLLKKAKKYGFADRKIAELWGRTESYIRQ
                     LRTEHKIVPVYKMVDTCAAEFESATPYFYSTYEWENESIRSEKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTEFSVSDKLYFEPLTLEDVLNVIDL
                     EKPKGVIVQFGGQTAINLAEPLAKAGIPILGTQVADLDRAEDRDLFEKALKDLGIPQP
                     PGQTATNEEEALEAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPEH
                     PVLVDSYIVGRECEVDAISDGKDVLIPGIMEHIERAGVHSGDSMAVYPPQTLSKEVQA
                     TIADYTKRLAIGLNCIGMMNIQFIIKDETVYVIEVNPRASRTVPFLSKVTDIPMAQVA
                     TKLILGQSLAELGYQDGLYPESNQVHVKAPVFSFTKLAKVDSLLGPEMKSTGEIMGSD
                     LTLEKALYKAFEASYQHLAEFGNVVFTIADEDKEEVLGLAQRFYELGYGLLATAGTAT
                     FLTENGLAVTTVGKLGDDSCPDIPSLVRAGKVQAIINTVGKKRVADGDGQVIRSSAIE
                     GGIPLFTALDTAEAMVKVLESRSFMTQAI"
     gene            18625..19380
                     /locus_tag="AC1PIV_000874"
     CDS             18625..19380
                     /locus_tag="AC1PIV_000874"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008990 - rRNA
                     (guanine-N2-)-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HIP6611909.1"
                     /translation="MIVTTSLGMDEGLVYRARRIASELGIEYKERKKQSVGKMLGTYE
                     AVLVLYKDKLILEQRGGQVLFFHPDTAMLRIKSGRDPLLELLGKEKQSIIDCTMGLGS
                     DSIVLASAGHRVTALESSKLVHFIVSRGLQDFDSGLQEVNRAMKSIQTIWTDSLTYLK
                     GQIDKSVDVIYFDPMFSEEIKESQNLSGLSTLADRSRLTEEIVSEAKRVARKKLIIKA
                     HFRDQVFEEFGFKRHVRPNQKFHYGEIILEEEV"
     gene            19377..20024
                     /gene="pcp"
                     /locus_tag="AC1PIV_000875"
     CDS             19377..20024
                     /gene="pcp"
                     /locus_tag="AC1PIV_000875"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HIP6611910.1"
                     /translation="MKIIVTGFDPFGGEPINPALETIKSLPKTIAGAEIILVEIPTVF
                     DKAADVLEEKMAEHLPDAVLCIGQAGGRVDLTPERIAINQDDARIPDNEGQQPIDRTI
                     REDGQPAYFSTLPIKAMVEAIHRIGLPASVSNTAGTFVCNHLMYQALYLAEKQFPKTK
                     AGFLHIPFLPEQVVDKPGLASMSLNDIVRGVEVAIGAIVEYRDKEDIKKGGGSTH"
     gene            20024..20332
                     /locus_tag="AC1PIV_000876"
     CDS             20024..20332
                     /locus_tag="AC1PIV_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4298 domain-containing protein"
                     /protein_id="HIP6611911.1"
                     /translation="MKNIMEARKRVEEMEKIFNRQLELNQSLSDSMAQLNQEQSTYLQ
                     LLDYYQSQTYMEDLDLSNKGYFNGIPCGVLSEDGVYNLLFDRTNLASQLRELADMLEQ
                     "
     gene            20456..20728
                     /gene="rpsP"
                     /locus_tag="AC1PIV_000877"
     CDS             20456..20728
                     /gene="rpsP"
                     /locus_tag="AC1PIV_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HIP6611912.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRAPRDGRFIETVGTYNPLL
                     AENSVTLKEERVLEWLAKGAQPSDTVRSLLSNAGVLKKFHEQKFSK"
     gene            20750..20992
                     /locus_tag="AC1PIV_000878"
     CDS             20750..20992
                     /locus_tag="AC1PIV_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HIP6611913.1"
                     /translation="MDMIENLIIAIVKPLISQPDSLTIKIVDTPEFLEYHLDLDQSDI
                     GRIIGRKGRTISAIRTIVYSVPTSDKKVRLVIDEKE"
     gene            21068..22804
                     /locus_tag="AC1PIV_000879"
     CDS             21068..22804
                     /locus_tag="AC1PIV_000879"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIP6611914.1"
                     /translation="MNLIWTYLKKYPKWIALDLLGAFLFVVVNLGLPTFLARMIDQGI
                     TKNDVSQLYFWAGMMGLIVLLGIVGRVTLAYAAGKLTTNIVKDIRNDLYEKIQDYSHH
                     EYEQIGVSSLVARMTNDAFVLMQFSEMVLKLGIITPLMMIASVIMTLVTSPSLAWTVA
                     VAMPFLVFVIFYVATKTRPLSEKQQKRLDTINQYVRENLMGLRVIRAFTREEFQEERF
                     ESVNEEYTDISKKLFNLTGLTEPLFVQIIIAMIVAIVWFALDPLKTGSLQIGDLVAFI
                     EYSFHALFSFLLFANLFNMYPRMSVSSQRIQEVLDMPISISKNEDGITETDTRGYLEF
                     ENVTFAYPGETESPVLHNISFKAKPGETIAFIGSTGSGKSSLVNLIPRFYDVTLGRIL
                     VDGVDVRRYNLKALRSKIGFIPQKALLFTGTIAENLKYGKMDASLAELHDATDVAQAK
                     EFIESKEEKFDTHLAEGGSNLSGGQKQRLSIARAIVKQPDIYIFDDSFSALDYKTDAI
                     LRSRLKEVTENATVLIVAQRVGTIMDADQIIVLNEGEIVGRGTHNELMESNEIYREIA
                     NSQLNRQSLTEE"
     gene            22813..24582
                     /locus_tag="AC1PIV_000880"
     CDS             22813..24582
                     /locus_tag="AC1PIV_000880"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIP6611915.1"
                     /translation="MKNRSVFTRVWDYLRRYKSSVFLAVFLKTISAVMNALEPFVLGL
                     IITELTKNLLDIANGVEGAQINYSYIAIMLAIYALRALLYEIGAYGSNYFMTKAVQGA
                     TKELRQDLSHKINKIPVSYFDKHQYGDLLGRFTSDVETVSNALQQSFLQLVNAVLTLS
                     LAIFMCFWLDVSLALVVVTLVPVTYFGSKFVMGKSQPYFKQQADALGRLNGFVQENLT
                     GFNVLKLYGREEISTEEFRQITADLQEVGFKASFMSGLLMPLVHGFSNIAYVVVALLS
                     GLKVLAGTLTVGNMQAFVQYVWQISQPVQTLTQLAPQLQSAKSSLERIFSVLDELDEE
                     DANALELTAGLTGQVSFEQVEFGYSEDKPLIRNFNLDVKPGEMVAIVGPTGAGKTTLI
                     NLLMRFYDVTSGAIKVDGQDIQNLSRQSYRSQFGMVLQDAWLYEGTIKENLRFGRLDA
                     TDEEIVEAAKAANVDHFIRTLPGGYNMEMNQESSNISQGQKQLLTIARALLADPAILI
                     LDEATSSVDTRLELLIQKAMKRLMKGRTSFVIAHRLSTIQEADKILVLKDGQIIEQGN
                     HESLLADKGFYYNLYQSQFSESK"
     gene            complement(24639..>25540)
                     /locus_tag="AC1PIV_000881"
     CDS             complement(24639..>25540)
                     /locus_tag="AC1PIV_000881"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HIP6611916.1"
                     /translation="RSRTQKKQLVPMLLGIALLVVTLLSIFLIFLKQPSKQQSDSKAS
                     TVETTTTSSVITSESSEVQTEIIWEQQTEPIKLPILMYHAIHVMAPEEEANANLIVDP
                     TTFESHLKALQDAGYYTLSPEEAYKVLTENVLPAGKKVVWLTFDDSLWDFYSYAYPLL
                     KQYQMKATNNVITGFTEYGQAGHLTLDQIKEMQTAGLSFQGHTVNHPDLEYSSIEDQT
                     NELTSSKAYLDSQLNQETIAIAYPGGRYSADTVALTEQAGYKLGVTTNNGLASASDGL
                     LTLNRVRILPTTTAEGLLSEISY"
BASE COUNT         7192 a         4767 c         5978 g         7603 t
ORIGIN      
        1 tcatgcgttg gttcgaatcc agctacccca gtaaaggtac tagatatagt ctagttcgtc
       61 aaagatgtct aattgttgtt gtccttgcgt gtgccttaaa taaaatatat tttatgttgg
      121 gtcgaaagac ctgattgtcg gaggtttttt tataatgaac gaatttgaag atttgttgaa
      181 cagtgtaagc gaagttacac ctggtgatgt ggtaactgca gaagtattga cagttgatgc
      241 tggtcaagca aacgtagcta tctcaggtac tggtgttgaa ggcgtattga ctcttcgtga
      301 gttgactaac gaccgtgatg ctgatatcaa cgaccttgta aaagttggtg aaacacttga
      361 attgttagta cttcgccaag ttgttggtaa agatacagac actgttactt atcttgtatc
      421 taaaaaacgt ttggaagcac gtaaagcatg ggacaagctt gttggtcgtg aagaagaagt
      481 tgttacagtt aaagtaactc gtgccgttaa aggtggtctt gcagttgaat ttgaaggtct
      541 tcgtggtttc atcccagctt caatgatcga cagccgtttc actcgtaaca ctgagcgttt
      601 tgtaggtcaa gaatttgatg ctaaaatcaa agaagttgat cctgctgaga accgtttcat
      661 cttgtcacgt cgtgacgttg ttgaagctgc agctgcagct gcacgtgctg aagtattcgg
      721 taaattggca gttggtgaag ttgtgactgg taaagttgca cgtatcacaa gcttcggtgc
      781 attcatcgac cttggtggtg tagatggttt ggtacacttg actgaattgt ctcacgagcg
      841 taacgtatct cctaaatcag ctgtaacagt tggtgaagaa gttgaagtta aagttcttgc
      901 aatcgatgaa gttgaaggtc gcgtatcatt gtcattgaaa gctacacagc ctggtccatg
      961 ggatggcgtt gagcaaaaat tggtagctgg tgatgtaatc gaaggtaaag taaaacgctt
     1021 gactgacttc ggtgctttcg ttgaagtatt gccaggtatc gatggtttgg tacacatttc
     1081 acaaatttca cacaaacgtg ttgaaaatcc aaaagacgct ttgtcagtag gtcaagaagt
     1141 aactgttaaa gttcttgaag tgaacgcagc tgatgagcgt gtatcacttt ctatcaaagc
     1201 tttggaagag cgtccagcag cagttgaagg tgaagaaaaa gctgaaaaac gtgctccacg
     1261 tccacgtcgt caaaaacgtg aagaaaaacg tgattacgaa ttgccagaaa ctcaatctgg
     1321 tttctcaatg gctgatcttt tcggtgacat tgaattgtaa ttcatataaa aacttgcctt
     1381 gtgcaagttt ttcctttcca cccttagtgt aatggatatc acgtaagatt ccggttcttg
     1441 agatgggggt tcgattccct cagggtggac taaattgaaa agcctgcatt aacaggcttt
     1501 tttgttatat tatatcaagg aggctatgat atgttacatt ttgaaaatga ctataacaaa
     1561 ggtgcccatc ccgccttgct agaagcctta gttgcaagca accaagaagg tttatctgga
     1621 tatggcactg ataaatatac tgaatctgct atcgaaaaaa tcagacttgc tacggactgt
     1681 cctcatgcac aagttacgtt tttagcaggt ggcacgcaga ccaatcaaat tgtcatttcg
     1741 tctatgttag cttcctatga aggagtcatt gcagcggata ctggtcatat tgcagttcat
     1801 gaagcagggg caattgaatt tacaggccat aaggtgttgg ccttaccgca tacggatggc
     1861 aaacttgtcg caagtgaagt tgagaactat atttccgatt tctacgcaga tgctaatcat
     1921 gctcacatgg ttcatccagg aatggtttat atttcccatc caacagagta tggtacactt
     1981 tatagcaagt cagagttaga agccttgtca acagtttgtc gtcatcataa catcccgctt
     2041 tttttagatg gagctcgttt gggttatggt cttgctgcac gcgatacgga tcttgatttg
     2101 aagacaattg cagagctgac agatgttttc tacattggtg ggacaaaact cggtgccttg
     2161 atgggggaag ctttggtatt tacaaagaac aaccagccta agaatttcgt atcgattgtc
     2221 aaacaccata gtgccttgtt ggcgaaagga agagtgacag gtatccagtt tgattgctta
     2281 tttactgatg acttgtatct tgaattgggg cgtcatgcta tagcaatggc agagcaactg
     2341 acccagattt tggaagagaa aggctttcaa ttctatctca aatccccgac caatcagcaa
     2401 tttgttattg ttaagaatga agaattgact agattgacag aagttggaat tgcctatggc
     2461 ttctgggaga aatacgacga tagccacagt atcatccgct ttgcgaccag ctggtcaact
     2521 agtcaagcgg atattgatgc gttaaggaat agattataat taataaaaaa gaaagggtta
     2581 gcctttcttt ttagtttgta aataatgata gcgataaact gcataacgtt caataaggcg
     2641 gtagcctatt ccccctgcga ttgcatgtac aatcagggca atgtgcaatt ctagtggtgc
     2701 ttttatagtg ataccaaata gaataccgat tacagtccat cctagtatca cccaccataa
     2761 gtacttaaat ggagcatact gaccatcctg gtctttaact tcactggaaa ccctgattga
     2821 acaaccggtc aatactccca tggggagcaa tgaacgagta tcaaatggtt ctggtaaaaa
     2881 tgacgataag gcgaagattt gtataagcgc aaaaatcagt agccaaacga aaatcggcgt
     2941 ttttagaatg acgtatttca tattgcacac ctcttgaaat tagtatatca aatccaagaa
     3001 tgtaaaacaa atatttttgt gctattgatt agaagtcgtt tcggatgccc cactagttac
     3061 ctctgtatca gtactggttt ctgtccttgt ctccaaagct tgggtagcag acgtttctgt
     3121 agacgaggaa gagacagtcg actctactaa agagctggtc tcggtttggg ttgaggatgt
     3181 tgtttcggag cttgaacttg ttgaatcttg tacttctgtt aatggattgt cgcttgatga
     3241 ttggctgggg ctagtggcgc tggatgatga aatggtagta cttggagatg ttgaggatgt
     3301 tgcaggtttt gctgtaaagg tgtagatagt gatgcaggca gtgataatcc ctaaaataga
     3361 cccgataaag gttaaatatt tttgaaaatt agttaaacca gccggttttt tatttgtatt
     3421 cttacgtgta ttcatgatgt acctccacct ttagtttaag ataggaagtt taaaactatc
     3481 ttaaagattg ccgaaaggca tgaaaacatg ataaaatagg actattgcaa taaaaggaat
     3541 ataaaaaatg atttattttg ataatgcggc aacgacacag gtctatccag aagttctcaa
     3601 gacctatacg gaagtggcga caaaaatctg gggaaacccc tctagcctcc atagtctagg
     3661 cagtcaggca acccgtattt tggaagcatc tcgcaagcaa atcgcagaat tgcttggcca
     3721 ggatagcaaa gaaatctttt tcacctcagg tggtacggaa ggtgacaact gggtcatcaa
     3781 gggagtggca tttgaaaagg cacacctggg caagcacatc atcgtttcgg ctatcgaaca
     3841 cccagccgta aaagaatctg cgctttggct caaaacgcaa ggttttgagg ttgatttggc
     3901 tccggtcaat gcccaaggtt ttgttgatgt ttcagcctta gaaagcttga ttcgtccaga
     3961 taccacactg gtttctatca tggccgtcaa caatgaaatt ggtgctattc agcccattca
     4021 ggaaatatct caactgttag ctgataagcc aaccatctca ttccatgtgg atgcggtgca
     4081 ggctatcggc aaagtgccga cggaacggta tttgacagac cgagttgatt ttgccagttt
     4141 ttcaggtcac aaattccact ctgtcagagg agtaggtttc gtctatatca aagctggcaa
     4201 gaaaatcgct ccgctattga cagggggagg acaggaaagc gataaacgct caaccacgga
     4261 aaatgtggct ggcattgctg cgacagctaa ggcgctccgc ttgaccttgg acaaggcagc
     4321 agatagccaa aagcgactgg cagccatgaa gcagatcctt gtggatgaat tgggcaaata
     4381 cgacgatgtg acagtttttt ctgggctaga ggactttgtg cccagtattg taactttcgg
     4441 aattaaaaac atccgtggcg aggtcattgt ccatgccttt gaagaccacc agatttacat
     4501 ttcgacaacc tcagcctgct cgtccaaggc tggaaaaccg gctggaaccc taattgctat
     4561 gggggttccg cagaagttgg ctcaaactgc cgtccgtatc agcttggatg atgacaacga
     4621 tatggggcaa atcgaacaat tcctcacgat tttcaaacaa atttatcaaa acacacagaa
     4681 agtaaggtag aatgaactat tcagaaatta tgattcgcta tggcgaattg tcaactaaag
     4741 ggaaaaacaa gatgcggttt gtcaacaaac tccgcaataa tatcaagcat gtcctttctg
     4801 tttacccaga agtgaccgtt tattttgacc gtgaccgtgg tcatgtctat ttgaatgggg
     4861 cggattatca ggaagtttca gcttctttga agaagatttt tgggatccaa aatttcgcac
     4921 cgtcttataa gattgaaaag tctgttccag ctttgaaaga agcggttgtg gaaataatgc
     4981 agaccattta caaggaaggg atgaccttca agattgctgc gcgtcgtagt gatcacagtt
     5041 ttgaattgga cagccgtgac cttaaccaag tccttggaga tgcggttttt acagctattc
     5101 caaatgtaca ggtacagatg aagtcaccag atattacctt gcgagtggaa atccgtcctg
     5161 atgctgctta tatttctcat gaagaaatca agggggcagg cggtctgcca gttggaacat
     5221 ctggaaaagg aacgcttatg ttatcaggtg gtattgattc gcctgttgcg ggctatttag
     5281 cactgaaacg tggggttgaa atcgaagccc tgcactttgc aagtccgcct tatactagcc
     5341 cgggtgcgct taaaaaagcc catgatttga ctcgcaaatt gactgccttt ggtggtaata
     5401 tcacctttat tgaagtgccg tttacagaaa ttcaggaaga aatcaaggaa aaggcacctg
     5461 aagcttattt gatgaccttg acacgtcgct tcatgatgcg gattacagac cgagtacggg
     5521 aagagcgtgg tgccatggtt attatcaatg gtgaaagtct aggacaagtg gcaagtcaga
     5581 ccctggaatc catgcaggct atcaatgcgg tgacaaatac acctgttatc cgtccagtcg
     5641 ttaccatgga caagttggaa atcattgata ttgcacaaga aattgatacc tttgatattt
     5701 ccatccagcc atttgaggat tgctgtacca tctttgcccc tgaccgtcca aaaactaacc
     5761 ctaaaatcaa aaatgtcgag caatacgagg ctcgaatgga tgtagaaggc ttggtggaac
     5821 gagctgtggc tgggattatc gtaactgaaa tcacaccgaa agaagaagtg aaagacgaag
     5881 tggatagttt aattgaagac ttactgtaga attcaattgt tttggcatac atttaaatcc
     5941 agctattgct ggatttttta atacgaatcg ttcggaaaaa tcgaatttgt atgatataat
     6001 aagacttcag aaaaaaacaa aggagttatt atgaaaaaag gagcactaac aggattactc
     6061 ctgtttggta tgttttttgg tgcaggaaac ttgattttcc cacctgcact tggtgtctta
     6121 tctggtgaga atttctggcc tgctatttta ggatttgtcg tttcgggtgt cggtattgca
     6181 gtcattgccc tgattgtcgg aacattgaac cccaaaggtt atgtacatga gatttctcgc
     6241 aagatttcac cgacttttgc aacgatttat cttgttgcct tgtatttggc gattggtcct
     6301 ttctttgcca ttccgcgtac agctacaacg tcctttgaaa ttggtattgc gccattattg
     6361 ggcgatgcga atctcggtct ttggttgttt ggctttacag ctctatactt tgtggcagct
     6421 tatctgattg ccctcaatcc atctcaaatc ttaaatagta tcggacgtat tttaacccct
     6481 gtttttgcga ttttgattgt gattttggtg gtgcttggta ttgttaagta cggatcaaca
     6541 agtccgttac cagcttcgga agcttactca gcaggacagg catttggtac aggatttatc
     6601 gagggataca atacactcga cgcacttgct tctattgctt ttagtgtcgt agcagtaaat
     6661 accttgaaac aacttggttt ctcaagcaaa agggaatatg tatcaactat ttggtctgtt
     6721 ggcttagttg tagccttggc attctcagct ctatatgttg gtttggcttt tttaggaaat
     6781 cattttcctg tgcctgcgga tgttttggct tccgatacca acaagggtgt ttacattctt
     6841 tcgcaagcaa cacaggctat ttttggacca ggtgcacaaa ttttcttagc tgctatggtt
     6901 atcgttactt gctttacgac gacggctggc ttgattgttt cttcaggtga atttttcgct
     6961 gagcgtttcc cacgttttag ctacaaagta tatgcgacta tctttacctt gattggcttt
     7021 gggattgcca acctcggttt gaacaatatc atcaccttct ctgttccagt tcttttggtt
     7081 ctctatccaa tcactatctg tattgtcttg attaccattg ttaacaaatt tgtaccgctt
     7141 tcgacttatg gtatgcaatt aactgtggga cttgtgacag ctttgtcatt ggtagaagtg
     7201 ttagcaggac aattcaactg gactgctgtt tcaaaaatca tctcagctct gccattggca
     7261 ggacaatcat tagcatggtt attaccagct cttgtcggaa tcgtcctctc tctattctta
     7321 ccaaacaagc aggagagcga agtttttgaa atgtaaaaaa atgatacaaa acacttgcat
     7381 ttgcaggtgt ttttgttata ataggactgt tgactatgca cacatcctgt gcaaccgcac
     7441 gaatgccgtt ctttcgttga gagtagagta agtggttcgt cccacggtac taggcgagtc
     7501 ttcacatcaa attcgggtaa gacccaaaaa tcataggagg tgcataatga gcacatatgc
     7561 aatcattaaa actggcggca aacaagttaa agttgaagtc ggtcaagcta tctacgttga
     7621 aaaattgaac gttgaagcag gtcaagaagt tactttcgaa gaagtagttc ttgttggtgg
     7681 tgagaaaact gttgtgggta ctccactcgt agcaggcgct actgttgttg gtactgttga
     7741 aaaacaaggt aaacagaaaa aagttgttac cttcaagtac aaacctaaaa aaggtagcca
     7801 ccgcaaacaa ggtcaccgtc aaccttacac aaaagttgtt atcaacgcta tcaacgctta
     7861 atcgcgtagc ttgaagcaat cattacagaa attcggagga ataacatatg ttaaacttga
     7921 atcttgctaa cttgcaattt atggcccaca aaaaaggtgg aggttcaacg tcaaacggtc
     7981 gtgactcaca agcgaaacgc cttggtgcga aagctgctga cggccaaact gtatcaggtg
     8041 gttcaatcct ttaccgccaa cgtggtacaa aaatctatcc aggagctaac gtaggtcgtg
     8101 gtggagatga cactctttac gctaaagtag aaggcgttgt acgcttcgaa cgtaaaggtc
     8161 gcgataagaa acaagtatct gtttatccaa tcgcaaaata agtctgaaaa tggctttaca
     8221 ataggctttc cgagttgttt tcggagagtc ttttttgtaa tttgattttg ctatttttaa
     8281 aagtgtacga tagaagtgat ttaagacggc aatatcttct ctataggata aaaatatttt
     8341 gccatctgca ctgttgcgct gcctataagt tctacgttca gtagtagatg aaatgttcag
     8401 aggaagtggt atgggttcca acttagtaaa attagtcatt gatgatttgg cgaacagaaa
     8461 ttccaaagcc tttcaaattg cagttgaaga agagaaattg ggaacctgga agttatacaa
     8521 gaaattagtt ttgaagaaca ggacgggcta gtctatttgc gaaaacgcaa gagttcagca
     8581 aattcttgct ttttttgata taatggtaga agcagtttta agaggtatca ggtatgaata
     8641 ttcaacaatt acgctacgtt gtagccattg caaacagtgg tacatttcga gaggcggctg
     8701 agaaaatgta tgtgtcccag cctagtttgt ccatttccat tcgtgatttg gaaaaagagt
     8761 taggttttca aatttttagc cgaactagtt caggaacttt tttgacacaa aaagggatgg
     8821 aattctatga gaaagctcag gctttagtta agggatttga tcagtttgag catctctatt
     8881 tgcaacctga ggaaggtgag aagacttttt caatttcaag tcagcattat gattttcttc
     8941 ccccattgat tacggagttc tctcgtagcc acccgcagta ccctcatttt cgcatttttg
     9001 aatctactac agtacagatt ttagatgagg ttgctcaagg ttatagcgag cttggtatta
     9061 tttatttgaa cgagagaaat acaaaaggaa tcatgcagaa attggataaa cttcacttgc
     9121 aagctgtaga tttgtctgca tttcagactc atatctacct tcgtgaagat catcctttga
     9181 caaagaaagc tgagattgat ccagtagatt tggtaggtct acctaccgta cggttcactc
     9241 aagaaaaaga ggcttatctt tattattccg agaacttgat tgatacgtcg gattcctcgg
     9301 tggtgtttga tgtgacagac cgtgctactt tgaatggaat tttggagcgt acggatgcct
     9361 atgcaactgg ttcgggctat cttgatgacg agagtgtcaa tggcattacc gtaattcctc
     9421 tcaaaggaaa ggtagacaat cgcatggtct acgttaaacg agctaatgat gaacttagtt
     9481 cttgtgccaa agactttatt gaaaccatgc aggcatattt tgataagaag aaggatgaaa
     9541 atgcgtaaaa ttggatttcc atttttgatg gtagtattaa ttggtttgga ccagtttgta
     9601 aaagcttgga cagttgccaa tattgaatta gatacggtaa cggaatttat accaggattg
     9661 atgagcttag cttatctaag aaattatggt gctgcctggt cgattttaca aaatcagcag
     9721 tggtttttca cgataatgac aattgttgct gtgacaggcc tagtgtggta ctatatcaaa
     9781 cagattaagg gcaatatctg gactttattc agtctgtctt tgatgattgc tggtgctctt
     9841 ggaaatttta ttgatcgtct tagattggga tatgtggtgg acatgtttca cttggatttt
     9901 attagtttcc ctgtatttaa tgtagcagat gtttgtctga cagttggtgt aggtatttta
     9961 tttatttgta ttatgaaaga agagagtaat ggaagtaaga gttgaggttg gtggtattcg
    10021 tttggataag gcattgtcag atttgacgga tttgtctcgt tcggttgcaa atgagcagat
    10081 taaggctggt caggttttgg tcaatggaca gcctaaaaaa gctaaatata gtgtgcaggt
    10141 tggggatgtt ctaacctatc aaattccaga agtagaagaa atcgactatg ttgctgagga
    10201 tattccttta gagattgtct ttcaggacga ggatgttgct gttgtaaata aacctcaagg
    10261 gatggtcgtt catccgtcgg ctggtcacac gtctggaacg ttagttaatg ctctccttta
    10321 tcacgtaaaa gatttgtcag gcatcaatgg tgtcttgcga ccaggtattg tccatcggat
    10381 tgacaaggat acatctggct tgctcatgat tgctaaaaac gatgatgccc atacaaagct
    10441 tgctgctgaa ttgaaagata agaaatccct tcgtaagtat tgggccattg tacacggcaa
    10501 tctaccaaac gatcgcggag taattgaggc gccgattggt cgttctgaaa aagaccgcaa
    10561 gaaacaagcg gtgactgcca aagggaaaga agcggtgaca cgttttcagg ttctggagcg
    10621 ttttggtgac tacactttgg tggaattgac cttggaaaca ggacgaactc accaaattcg
    10681 cgtccacatg gcttatattg gtcatccggt tgcgggtgat gaagcttacg gcccaaggaa
    10741 aacactaaaa gggcatggcc aatttcttca tgccagaacg cttggattta cccatccgag
    10801 aactggtgag gttgttgaat ttacggcaga agcgccagct atttttcagg aggcacttga
    10861 aaaactgcgc aaggctgaat aatagtatga aaaccttatc atcttgccca ttttttcaac
    10921 aaatgctata ctagaacatg aaaaatgtta aggagagtaa gaatggaaac tttaccaaat
    10981 tgtccaaaat gtaattctga atatgtctat gaagacggtg ccctcttggt ttgccctgag
    11041 tgtgcatacg aatggaaccc agcagatgta gctgaggaag aaagtggacc tgttgcaatt
    11101 gatgctaacg gtaatcgttt ggcggacggc gatactgtga cgcttatcaa agatttgaaa
    11161 gtgaaagggg cgcctaagga ccttaaacaa ggtacacgtg ttaaaggcat ccgtatcgtt
    11221 gaaggtgatc acaatattga ttgtaaaatc gatggtttcg gtgccatgaa gttgaaatct
    11281 gaatttgtta agaaaatcta agagagagga ctggttaacc agtcttttcc tgtttttgaa
    11341 aggatattat gaaacatcaa agtattttgt tttacagtag atgcctgtta gctattttag
    11401 ccatcacagg taccgcctta gaaatcatta aatattgtat cgggatgctc atgtattata
    11461 cggtacaatc taatttatta gtatctctgt tcgctgtcta tatggtctat gccatgagta
    11521 agggtgtgga tttacagacg tcacgttttc ttcggataaa ggctgctgta accatgtcta
    11581 tcatgattac ctgtgtagtc tatcacttta tgttggcacc tttggcagac gatttctggc
    11641 gacttgaaaa tctactctgc cattatattg ttcccttata ttttttgtta gataccctaa
    11701 tagtagatcg tcagcaacag tacaagtggt ttgacccgat ttggtggacg cttttgcctg
    11761 ttctttacat gatttttggt ctagtgaatg gtcttttcat aaaaattcca atcccagatg
    11821 ctaaggacag tccttttgct tatttctttc tcaatgtccc taagtatggt tggacctatg
    11881 ttttgactta tgctggagtc atctttgtcg cctatctagt ctgcggtttt ctattggcgg
    11941 gactaaaatc cataaacctt aagacttcat tgtcttttgg aaaaaattct cagtaaaatc
    12001 cgataatttc tatatttttt cagaaaaaaa ttgtcaaggc tgagatttta tgctatactc
    12061 tgcttaataa atcctttaaa acctgtccag agaggcagac aaggagtcgg atgttaagca
    12121 ggttggttct aactagccta tattttcata gtctccttgt ataaggagac tttttctata
    12181 cttttggagg tcttatgaag acaaaagaaa tcgttgacga tatgactatg aaacgggcaa
    12241 tcacccgcat cacttatgaa attatcgaac ggaataagaa tttggataat attgtccttg
    12301 cagggattaa aacacggggt gttttcattg caaagaggat tcaggagaga cttaagcaat
    12361 tagagggtat cgacgttccg ttgggtgagt tggataccaa accgtttcga gatgacatga
    12421 aggtagaaga tgatacgaca aatatgactg ccaatgtcaa cgatcgtgat gttatattag
    12481 tagatgatgt gctttataca ggacgaacta ttcgtgctgc tattgacaac atagtgtcct
    12541 tgggccgtcc agctcgtgtt agtttagcgg tacttgtgga tcgtggacac agggagttgc
    12601 ctattcgagc agattatgtt gggaagaata tcccaactag ccgttctgaa gaaatcattg
    12661 tgcacatggc tgaaatcgat ggtcaagacg ctgttcttct ggttgaaggt gcatagtcgc
    12721 ttcgtttaca aattctcatt ctacatctag atcataaagg taggtatcat catgacaatt
    12781 acaaatggta aagtttcact caaacacttg gttacaatgg agaccctctc aaatgaagaa
    12841 gtattgggac tcattcaacg tggtattgct tttaaacgcg gtgaaaaggt agagttagat
    12901 cggaagtact atgcttctaa ccttttcttt gaggattcaa ctcggacgca taagtctttt
    12961 gaaatggcag agcttcgttt ggatatggga atgattgact ttgatgctcg taccagctca
    13021 gtcaataagg gtgaaacctt gtgtgatacc attttgacca tgtcggcact tggggtagac
    13081 atctgcgtga ttcgtcactc ggaagtggat tattacaagc aattgattga tagtcctacc
    13141 attcagactt caattgtcaa tggtggtgat ggttcaggtc aacacccaag ccaatcccta
    13201 cttgatttga tgactattta tgaagaattt ggaacttttg acggcttgaa gattgccatt
    13261 gcaggtgata ttacacactc acgggttgct aagtccaata tgcaaatttt gaagcgtctg
    13321 ggagctgaga ttttctttgc tggaccggag gaatggtacg cagaggaatt tgacgtctat
    13381 ggtcagcatt tgaatattga tgatattgtg gaaacggtag atgtactgat gttgctccgt
    13441 gtgcaacacg agcgtcatga tggtgatggt ggtttttcta aagaaactta taaccgtttg
    13501 catggtttaa cagaggagcg ctacaaacgc ttgaaagata ctgcaattgt tatgcatcct
    13561 gcccctgtta accgcgatgt tgagattgat gattctctag ttgaagcacc caaatcacgt
    13621 attgtccgtc aaatgcagaa tggtgtattt gtccggatgg cgattttgga agcaattgtc
    13681 aatggcaagg cttaaaagta agctgttcag gtatcttaga actgagcagt tagaaatttg
    13741 ttagacttat cttatttaat gtcgcccaga gaggcgacga atagaaagga gaaggtacag
    13801 gttcgagtaa gatttgattt ttatattcga acacgcccta aggactgtgt gaaaaagata
    13861 aatatcgact tgacgcctat agcgtcggcg ccgaatttcc tattttcact ttgtcctttt
    13921 aacgggcttt gtatcataga ttatgtcaaa aagacgttta attttggaaa atggcactat
    13981 ttttgagggg gaggccttcg gtgctgatat tgatgtgact ggtgagttgg ttttctcaac
    14041 tgggatgaca ggttatcagg aatccatcac ggaccagtct tataatggtc agattttaac
    14101 ctttacctat cccttggtag gaaattacgg gattaaccgt gatgatttcg agtcgatcaa
    14161 accgacttgt aagggagtgg ttgttagcga gtgggctcgt cgagcaagta attggcgtaa
    14221 ccagatgact ttggatgaat ttttaaaggc taagaaaatt ccagcaattt ctggaattga
    14281 cacacgcgcc ctaactaaaa ttattcgtca gcacgggacc atgaaggcga cattggcaaa
    14341 tgttggtgat tccgttgagc atttgacaga ccagttgaga gcgactattt tgccaaccaa
    14401 caacatccag caagtatcga caaaaacagc ctatcctgca cctggagttg gacgtagtgt
    14461 tgttttggtt gattttggat tgaaacattc tattcttaga gagttagcca agcgtgattg
    14521 caatgtgaca gttgtccctt atgatacgac tgctgaagaa attcttgccc tcaatccaga
    14581 cggtgtcatg ctttcaaacg gtcctggtaa cccagatgat gttccagaag ctttggacat
    14641 gattcggggc attctcggaa aaattccaat ttttggtatc tgtatggggc accaactctt
    14701 tgctaaagca aatggggcaa cgacttataa aatgaagttt ggtcaccgtg gtttcaacca
    14761 tgctgttcgt gaaattgcga caggtcgagt ggactttacc agtcagaacc acggttatgc
    14821 agtggctcgt gaagatttac ctgaatgttt aatgattact catgaagaaa tcaatgacaa
    14881 atcagtagaa ggggtacgcc acaagtacta tccaggtttc tctgttcaat tccacccaga
    14941 tgctgcacct ggtccacatg atgccagcta tttgtttgac gaatttatgg aattgatgga
    15001 ttcgtttaaa aaagggcagt aaggtttaac tactatcgag ctaaacctta ctgcgtcggt
    15061 cagagcaagt cggacttcat gctaacgcat gtgtcctcct acgcaaagtc caatgggacc
    15121 tttgctaact ctgacactag tttagaattt caattattat cgaattgaga ttctaaacgt
    15181 cggacttatc ttatttaatg tcgctcagag aggcgacgaa tagaaaggag aaggtacagg
    15241 ttcgaataag atttgatttt catattcgaa cacgccctaa ggactgtgcg aaaaagataa
    15301 acgtcgtctt gatgcttgaa gcatcagcgt cgtgtttcct attttcgctt tgtcctctta
    15361 acgggctttg tatcatacat tatgccaaaa cgtacggata ttaagaaaat aatggtgatt
    15421 gggtctggtc cgattgtgat tggtcaggct gcggagtttg attatgctgg gactcaggct
    15481 tgtttagcct tgaaggaaga aggttacagt gtggtcttgg tcaattcaaa ccctgcgacc
    15541 attatgacag acaaggaaat agcagacaag gtttatattg agccaattac gcttgaattt
    15601 gtcacacgga ttttacggaa ggagcgtcca gatgctttct tgccaactct tggtggtcag
    15661 actggtctca acatggccat ggaattgtct aaggctggta ttttagatga gcttggagtt
    15721 gagttgttgg gaactaaact gtctgcaatt gatcaggcag aggaccgcga cctcttcaaa
    15781 caactcatgg aagatctcaa tcagcctatt cctgagtcaa cgattgtgac aacagttgat
    15841 gaggctttgg aatttgctgc tgaaattggt tatcctgtca ttgttcgacc agccttcacg
    15901 ctgggtggta ctggcggtgg tatgtgtgcc aatgaagaag aactacgtga aatagcagaa
    15961 aatggtctaa aattgtcacc agtgactcag tgtttgattg agcgttccat tgctggtttc
    16021 aaagaaattg aatacgaagt gatgcgggat gcggctgaca atgccttggt cgtatgtaac
    16081 atggaaaact ttgaccctgt gggaattcat acaggagatt ctatcgtatt tgccccaacg
    16141 cagacgcttt cggatattga aaaccagatg ttgcgtgatg ccagtctcag cattattcgc
    16201 gccctcaaaa tcgaaggtgg ctgtaatgtg cagttggcat tggatccaca tagtttcaaa
    16261 tattatgtca ttgaagtaaa cccacgtgtg tcccgttcgt ctgccttggc atccaaagcg
    16321 acaggttatc ctattgccaa attggcagca aaaattgcgg ttggcttgac cttggatgaa
    16381 atggtgaacc ctgttacagg aacaacctat gccatgtttg aaccagctct tgactacgtt
    16441 gtggcaaaaa ttccacgttt cccatttgat aagtttgaaa aaggggaacg ccgccttgga
    16501 acgcagatga aggcaactgg ggaggtcatg gccattgggc gtaatatcga agaaagtctg
    16561 ctcaaggcct gccgttcttt agaaatcggt gtttaccaca atgaaatgcc agaactcagc
    16621 caagtgacag atgaccaatt ggttgaaaag attgtcaagg cacaggatga tcgactcttc
    16681 tatctttcag aagcccttcg acgtggctat accgtagaag aactggctca attgacgaag
    16741 attgatcttt tcttccttga taagctgctt catatcttag aaatcgagca ggaattggca
    16801 acgaattttg ataatattga tttattgaaa aaagccaaga aatacggttt tgcagaccgc
    16861 aagattgcgg aactctgggg acggacagaa tcctacattc gtcaactgcg gacagaacac
    16921 aagattgtcc ccgtttacaa gatggtagat acttgtgcgg ctgagtttga aagtgctaca
    16981 ccttatttct attcaactta tgagtgggaa aatgagtcca tccgttcgga gaaagaatct
    17041 gttttggtgc tgggttctgg tccaattcgt atcggacagg gtgtggagtt tgactatgcg
    17101 acggtacatt ctgtcaaggc cattcaggca gctggctacg aggccattat tatgaactca
    17161 aaccctgaaa ctgtgtcaac tgagttttcg gtttcggaca agctttattt cgagccgttg
    17221 accttggaag atgttttgaa tgtgatcgac cttgagaaac caaaaggggt tatcgttcag
    17281 ttcggtggcc agacggctat caatttggca gagccattgg ccaaagcagg cattccaatc
    17341 ttggggacac aggtggcgga tttggataga gctgaagaca gggatttatt tgaaaaagcc
    17401 ctgaaagacc tagggattcc acagccacca ggccaaaccg caaccaacga agaggaagct
    17461 cttgaagcgg cccgcaaaat tggtttcccg gtacttgttc gtccatcata tgttttgggc
    17521 ggtcgtgcta tggagattgt cgaaaatgaa gaggacttac gttcttatat gagaactgcg
    17581 gtcaaggctt cgccagagca cccagttttg gtggattctt acatcgtcgg tcgtgagtgt
    17641 gaagtggatg ctatttcaga tggtaaggat gtcttgattc cgggtattat ggagcatatc
    17701 gagcgcgctg gggttcactc aggtgactcg atggccgttt atccgccaca aaccttgtcc
    17761 aaagaagtgc aggcgaccat tgcagactac accaaacgct tggcaatcgg tctcaactgt
    17821 atcggtatga tgaatatcca gtttatcatc aaggatgaaa cggtctatgt gattgaggtc
    17881 aatcctcgtg ccagtcgtac ggttccattc ttgtccaaag tcacagacat tccaatggct
    17941 caggttgcaa ccaaattgat tttgggacaa agccttgcgg aacttggcta ccaagacggt
    18001 ctttatcctg agagcaacca agtgcacgtc aaggcaccgg tcttctcgtt cacgaaacta
    18061 gctaaagttg acagtttgtt aggaccagag atgaagtcaa ccggtgagat tatggggtca
    18121 gacttgacac tggaaaaagc gctttataag gctttcgagg caagttatca gcacctggct
    18181 gagtttggca acgttgtctt taccattgcg gatgaagaca aggaagaagt gcttggtctg
    18241 gctcaacgtt tctatgaact tggttatggc ctactggcca cggcaggaac agccaccttt
    18301 ctaacagaaa atggacttgc tgtaacaact gttggtaaat taggcgatga ttcctgtcca
    18361 gatattccta gtcttgttcg ggcaggtaag gttcaggcta ttatcaatac ggttggtaaa
    18421 aaacgggtgg cagatggtga cggtcaagtc attcgaagct ctgctattga aggaggaatt
    18481 ccgctcttta cggccctcga tacagcagaa gctatggtca aagtgctgga gagtcgtagc
    18541 ttcatgacac aggctatata gaagatacta tcaggatgag ctttgaattc gtcctgattt
    18601 tttgatatac tgaagagtat gaaaatgatt gtaacaacta gtcttgggat ggatgagggg
    18661 ctggtctata gggctagacg gattgccagt gaactgggaa ttgaatacaa ggaaagaaag
    18721 aagcagtcgg ttggaaaaat gttaggtacc tacgaggctg tcttggttct ttataaggat
    18781 aaattgatac tagagcagag gggtgggcag gttttatttt tccacccaga tactgccatg
    18841 ttgcggatta agtctggaag agatccgctt ttagaattac ttggaaaaga aaaacaatca
    18901 ataatagact gtactatggg cttgggatct gatagcattg tgttagcaag tgccggtcat
    18961 cgggtgacag ccttggaaag ttctaagcta gtgcacttta ttgtgagtcg aggtttacag
    19021 gattttgata gtgggctgca agaggtcaat cgagccatga aatctattca gacaatttgg
    19081 acagatagtt tgacttattt gaaagggcaa atagataagt ctgttgatgt catttacttt
    19141 gatcccatgt tttcagaaga aatcaaggaa tcacaaaatc tttctggctt gtctactttg
    19201 gctgacagaa gccgtttaac ggaggaaatt gtatctgagg ctaaacgagt agctaggaag
    19261 aaattgataa taaaggctca ttttcgagat caggtctttg aagaatttgg ctttaaacgt
    19321 catgtcagac ccaatcaaaa atttcactac ggagaaatta ttttggagga ggaagtatga
    19381 aaatcatcgt aacaggcttt gatccctttg gcggcgagcc tattaaccca gccttggaaa
    19441 caatcaaatc tctacctaag accattgctg gtgcagagat tattcttgta gagattccga
    19501 ctgtttttga caaggctgcg gatgttttag aggagaaaat ggcagaacat ttacctgatg
    19561 cggtactatg tattggtcag gctggtgggc gagttgattt aactcctgag cgtatagcca
    19621 ttaaccaaga tgatgcacgc attccagaca atgaggggca acagccgatt gatagaacga
    19681 ttcgagaaga tggtcagcct gcttatttct ccaccttacc catcaaagca atggttgaag
    19741 ctattcatag gattgggctt ccagcttctg tttctaatac tgctgggacc tttgtctgca
    19801 accatctcat gtatcaagct ctttacttgg cggagaaaca atttccaaag actaaggcag
    19861 gctttctcca tattcccttc ttgccagagc aggttgtcga caaaccagga ctggcttcca
    19921 tgtctttgaa cgatattgta agaggagttg aagtagctat aggagcgatt gttgaatata
    19981 gggataaaga ggatattaaa aagggtggtg gcagtacaca ctgatgaaaa atattatgga
    20041 agcaagaaaa cgtgtagagg aaatggaaaa aatatttaac agacagctag agctgaacca
    20101 gtccctttcc gatagtatgg cacaactcaa ccaggaacaa tcgacttatt tacagttatt
    20161 agattattac cagagccaga cctatatgga agatcttgat ttatctaata agggttattt
    20221 caatggtatt ccttgcggag tattgagtga agatggagtc tataatttac tgtttgaccg
    20281 tacaaatcta gcaagtcaac tgagagaact agcagatatg ctcgaacaat aaatttttta
    20341 aaacctgtca agtttttttc ttgacaccct gttaaagtgt ggtataatag aacatgtgct
    20401 aaatagctct gctatttcac cgaataaaaa tacaaagaaa agagaacatt taaaaatggc
    20461 agtaaaaatc cgtttgactc gtatgggttc taaaaagaaa cctttctacc gtatcaacgt
    20521 tgcagactca cgtgcaccac gtgatggtcg tttcatcgaa actgttggta cttacaaccc
    20581 acttttggct gaaaactcag taactcttaa agaagagcgt gtacttgagt ggttggcaaa
    20641 aggtgcacaa ccatctgata cagttcgtag ccttctttca aacgctggcg tattgaagaa
    20701 attccacgaa caaaaattct ctaagtaaga acagtaagcg agaacactta tggacatgat
    20761 tgaaaatctc attattgcga ttgtgaaacc tttgatttca cagcctgata gcttgacaat
    20821 aaaaattgtt gatacacctg aattcttgga atatcatttg gatttggatc aatctgatat
    20881 tggacgtatc attggtagaa aaggacgcac aatttctgca atcagaacga ttgtctattc
    20941 tgttccaaca agtgataaaa aagttcgttt agtgatcgac gagaaagaat agaaagtcac
    21001 cgtttggtgg cttttaacgt tgacaaaggg gcctagcccc tttttaacat atagaaagga
    21061 agaaatgatg aatctgattt ggacctattt gaaaaaatat cctaagtgga ttgccttaga
    21121 cttgttgggg gccttcttat ttgtagtggt aaacttaggc ttgccgactt ttttggctag
    21181 gatgattgac caaggaatta caaagaacga tgttagtcag ctctatttct gggcggggat
    21241 gatgggattg attgtcctgc tcgggattgt tggtcgagtg acacttgcct atgcagctgg
    21301 aaagttaact acaaatatcg tcaaggatat tcgaaatgat ctgtatgaga aaattcagga
    21361 ctattctcat catgaatatg agcagattgg tgtttcttct ctagttgctc gtatgacaaa
    21421 tgatgctttt gttctcatgc aattctctga aatggtctta aaactaggta ttattacccc
    21481 cttgatgatg attgcttctg tcatcatgac cttggtaacc agtccgagct tagcctggac
    21541 agtagcagta gccatgccgt ttctagtttt tgttattttc tatgtggcaa caaaaactcg
    21601 tcctctctct gaaaaacaac aaaaacgttt ggatacgatc aaccaatatg ttcgtgaaaa
    21661 tctcatgggc ttacgtgtca ttcgtgcctt tactcgtgag gagtttcaag aggagcgctt
    21721 tgagtcggtc aatgaggaat ataccgatat ttccaaaaag ctctttaatc tgactggatt
    21781 gacagagcct ctctttgtcc agattatcat tgctatgatt gtggccattg tctggtttgc
    21841 tttggatccc ttgaaaacag gcagtctgca aatcggtgat ttggtagcct ttatcgaata
    21901 tagtttccac gcgcttttct ctttcttgct ctttgctaac ttgtttaaca tgtatccacg
    21961 tatgtcggta tcgagccaac ggattcagga agtcttggac atgcccattt ccatttctaa
    22021 gaatgaagac ggcataactg aaacagatac tcgtggttat ttggaatttg aaaatgtaac
    22081 ttttgcctac cctggtgaaa cggaatcgcc tgtgctgcac aatatttcct tcaaagctaa
    22141 gcctggtgaa acgattgcct ttattggttc aacaggttct ggtaagtctt ccttggtcaa
    22201 cttgattcca cgtttctatg atgtgacact tggtcgtatc ttggtggacg gtgtggatgt
    22261 cagacgctac aatctaaagg cactccgcag caagattggc tttattccgc agaaagctct
    22321 gctatttacc ggaactatcg cggaaaactt aaagtacggt aagatggatg ctagtcttgc
    22381 agaacttcat gatgcgacgg atgtggctca ggctaaggag tttatcgaga gtaaggaaga
    22441 aaaattcgac acccatctag cagaaggtgg aagcaacctg tcaggcgggc aaaagcaacg
    22501 tttgtccatt gcacgtgcta ttgtcaaaca gccggatatt tacatttttg atgattcttt
    22561 ctcagccttg gattataaga cggatgcgat tttgaggagt cgtttgaagg aagtgacgga
    22621 aaatgcgacg gtgctaattg tggcccaacg tgtcggaacc attatggatg ctgaccagat
    22681 tatcgtgctg aacgaaggtg aaatcgttgg ccgcggcacc cacaatgaat tgatggaaag
    22741 caatgagatt tatcgagaaa tcgccaattc tcagcttaac cgtcaatcgt taacagaaga
    22801 ataggaggaa ttatgaagaa tagatcagta tttacccgtg tttgggacta tttgcgtcgt
    22861 tacaaatctt ctgtattttt agctgttttt ctaaagacca tcagtgcagt tatgaatgcc
    22921 ttggagccct ttgtactggg gcttatcatt acagaattga ccaagaatct gttggatatt
    22981 gctaatggag tagaaggagc gcagattaac tattcctaca ttgccatcat gcttgccatc
    23041 tatgcccttc gcgcccttct atatgaaatc ggtgcctacg gttctaacta ttttatgacc
    23101 aaggcagtgc agggagcaac taaggaacta cgtcaggatt tgagtcacaa aattaacaaa
    23161 attcctgttt cttactttga taagcaccag tatggtgatt tactcggacg ttttacaagc
    23221 gatgtggaga ctgtttcaaa cgccctgcaa caaagttttc tccagctagt caatgccgtt
    23281 ctgaccctct ctctagccat tttcatgtgt ttctggttgg atgtatccct agcacttgta
    23341 gtcgtaacct tggttccagt gacttatttt ggttctaagt ttgtcatggg caaatcccag
    23401 ccatatttca agcagcaggc tgatgcccta ggtcgtttga acggctttgt ccaagaaaat
    23461 ctgactggtt ttaacgttct caaactctac ggccgtgaag aaatttctac agaagagttt
    23521 cgccagatta ccgcagattt gcaggaagtt ggtttcaagg ctagtttcat gtctggtttg
    23581 ctcatgcccc tggtacacgg cttctcaaat atcgcctatg ttgtcgtcgc cctgctatct
    23641 ggattgaaag ttcttgcagg tacattgacg gtgggtaata tgcaggcctt cgtccaatac
    23701 gtctggcaga tttctcagcc agtccaaacc ttgacccagt tggcaccaca gttacagtct
    23761 gccaaatctt cccttgaacg catcttttca gtcctagatg agcttgatga agaagacgcc
    23821 aatgcgctgg agttgacagc tggtttgacc ggacaagtca gctttgaaca ggtcgaattt
    23881 ggctattcag aagacaagcc gcttatccgt aactttaatc ttgatgttaa gccaggtgaa
    23941 atggttgcta tcgttggtcc aacaggggca ggtaagacaa cccttatcaa cttgctcatg
    24001 cgtttctatg atgtcacatc aggtgctatc aaggtagatg ggcaggatat tcaaaatctt
    24061 tcacgtcaat cctaccgtag tcaatttggt atggtcttgc aggatgcttg gctctatgaa
    24121 gggaccatca aggaaaacct acgttttgga cgtctggatg cgacggatga ggaaattgtg
    24181 gaggctgcta aagctgccaa cgttgaccac tttatccgta ccctgcctgg cggttataat
    24241 atggaaatga accaggaatc cagcaatatt tcccaaggtc agaaacagct tttgaccatt
    24301 gcacgtgcct tgttggcgga tcctgctatt ctgattcttg acgaagcgac ttcttcagtt
    24361 gatacccgtt tggaactctt gattcaaaag gccatgaaac ggttgatgaa agggcggaca
    24421 agtttcgtca tcgctcatcg cttatctacc attcaggaag ctgataagat tttggtcttg
    24481 aaagatggac agattatcga acaaggtaac catgaaagtc ttttggcaga caaaggtttc
    24541 tattataatc tttatcaaag ccagtttagt gaatccaaat aaaaaacgaa ctcccttgtc
    24601 agtgacaggg agttttctca tatacatgtt tgtgaaaatt aataggaaat ttcggataat
    24661 agtccctcag cggtagtggt tgggaggatg cggacacgat tgagagtcag taatccgtca
    24721 ctagcagaag ccaagccgtt gttagtagtc acaccaagtt tgtagccagc ttgttcagtt
    24781 aaggctacgg tatctgctga gtatcgtcca ccagggtagg cgatagcgat ggtttcctga
    24841 tttaattggc tgtcaagata ggctttagag gaagtaagtt catttgtttg atcctcgata
    24901 gaactatact ctaaatcagg gtggttgacg gtatgccctt gaaaggagag ccctgcggtc
    24961 tgcatttcct tgatttgatc aagagtaagg tgccctgctt gtccatattc agtaaatcct
    25021 gtaatgacat tgttggttgc tttcatttga tattgcttaa gcaatgggta ggcataacta
    25081 taaaaatccc agaggctatc gtcaaaggtt agccagacaa cctttttgcc agcaggaagg
    25141 acattttctg tcaatacctt ataagcctct tcaggtgata aagtatagta acctgcatct
    25201 tgcaatgctt ttagatgact ttcgaaagtc gttggatcta cgataagatt cgcattagct
    25261 tcttcctcag gagccattac gtgaatggca tgatacatga ggattggaag tttgataggt
    25321 tcagtttgtt gttcccaaat gatttctgtt tgtacttcac tactttctga agttataaca
    25381 cttgaagtgg ttgttgtctc taccgttgaa gctttggaat cactttgttg cttagatggc
    25441 tgttttagaa agattagaaa aatagatagt agagtcacta ctaataatgc gatgccaagt
    25501 agcattggca caagttgttt cttttgtgtg cggcttcgac
//
LOCUS       DBNFCO010000026        23613 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.026, whole genome shotgun sequence.
ACCESSION   DBNFCO010000026 DBNFCO010000000
VERSION     DBNFCO010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 23613)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23613)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23613
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.026"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            <1..1287
                     /locus_tag="AC1PIV_000882"
     CDS             <1..1287
                     /locus_tag="AC1PIV_000882"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HIP6611917.1"
                     /translation="VHNYVHVDHELIYKLINTKEFQRLRRIKQLGTTSYTFHGGEHSR
                     FSHCLGAYEIARRITQKFEDKYPQIWDTNESLLTMVAALLHDVGHGAYSHTFERLFDT
                     DHEEMTCAIITSPETEINALLKQVSPEFPDKVASVIKHTYPNKQVVQLISSQIDVDRM
                     DYLLRDSYFTGANYGEFDLTRILRVIRPTENGIAFKESGMHAVEDYVLSRYQMYMQVY
                     FHPASRSMEVLLQNLLNRAKLLYTGEQEFFARTSPRLLPFFEHRIRLTDYLSLDDGVM
                     NTYFQSWIDGPDRILSDLAQRYINRKVLKSITFKAEEEEALDRLRSLVADVGFDPEYY
                     TAIHHNFDLPYDIYRPNAEKKRTQIEIYRKDETLVELSSLSPIVHSLSGTIHGDSRFY
                     FPKEMLEETGIFAPQIADFNSHIHNDHFIIGESNEH"
     gene            1277..2086
                     /gene="yidA"
                     /locus_tag="AC1PIV_000883"
     CDS             1277..2086
                     /gene="yidA"
                     /locus_tag="AC1PIV_000883"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HIP6611918.1"
                     /translation="MSIKLVAIDIDGTLLNSQHQITAEVHSTIQEAKKAGVKIVIATG
                     RPISGVQAILEELNLTEAGDYVITFNGGLVQDAATGEDIVKDTLTYEDYLDIESAARK
                     LKLPMHASTKEGIYTANRNIGKYTIYESTLVSAPIFYRTPEEMADKEIIKTMMVDEPE
                     ILDAAIPLLPTILTEKYNVAKSAPFYLEITPKTVNKGQAIIHLAEKLGLTMDQTMAIG
                     DQENDRPMLEVVGNPVVMENGNPELKKIAKYITKSNDESGVAHAFREWVLK"
     gene            complement(2139..2891)
                     /gene="tpiA"
                     /locus_tag="AC1PIV_000884"
     CDS             complement(2139..2891)
                     /gene="tpiA"
                     /locus_tag="AC1PIV_000884"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HIP6611919.1"
                     /translation="MSRKPIIAGNWKMNKNPQEAQAFVEAIAGKLPAGDKIEAAIAAP
                     AVDLNALLWFAKDSELKVAAQNCYFEDAGAFTGETSPKVLAEMGVNYVVIGHSERRDY
                     FHETDEDINKKAHAIFRNGLTPIICCGESLETYEAGKAVEFVGAQVSAALKDLTADQV
                     ASLVIAYEPIWAIGTGKSATKDDAQNMCKAVRDVVAADFGQEVADKVRVQYGGSVNPS
                     NVAEYMACPDVDGALVGGASLEAESFLALLNF"
     gene            complement(3066..4262)
                     /gene="tuf"
                     /locus_tag="AC1PIV_000885"
     CDS             complement(3066..4262)
                     /gene="tuf"
                     /locus_tag="AC1PIV_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HIP6611920.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGTVRVNDEIEIVGLQEEKSKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVISKPGSINPHTKFKGEVYILTKEEGGRHTPFFDNYRPQ
                     FYFRTTDVTGSIKLPEGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(4618..5589)
                     /locus_tag="AC1PIV_000886"
     CDS             complement(4618..5589)
                     /locus_tag="AC1PIV_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009909491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti sigma factor C-terminal domain-containing
                     protein"
                     /protein_id="HIP6611921.1"
                     /translation="MTMKTFEEVTKKSKRKNLWKTVGLSSFIGFILLLIGIQTVKIIV
                     GAREGSENWKQIILMEISYPNIKHDGIKIQSTSYVSGKLYCNLYKDLAGVPMAFGQHE
                     IYYDLFDRHYDFAQHIPGNTFKYLYDFTTNTKIPVFYNRKKSVWSVQDIANELHYLKD
                     MSGQLVEVAISFDKKYSLAEIKQMIPSNLKQNWYWIGTEGKQNTHYYRPEQLLGLDPE
                     DIQLVFSDMPGDYMTGMDFMKEFLESGDQKRAQYLDIPVDDLQAFVDKFGDTDFTKQE
                     EIDKLEFAGIILTGKAEDFAQLEGKDWIYSSSIGASIPIQPYYQLHH"
     gene            complement(5570..6073)
                     /locus_tag="AC1PIV_000887"
     CDS             complement(5570..6073)
                     /locus_tag="AC1PIV_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HIP6611922.1"
                     /translation="MSIKLDQYEKEVIGIAEEISYYLQKSGANYADSQDIAQDILVKI
                     LEAELVLPFEKLRAWLYRSAVRAYIDKYRRDKRYHEILQKEFFTPENFLVYDQEDYEE
                     LYQAVADLPEKYQQVIDLYYFQDMSIKEIAHILGAGQSWVKISLHRGRKQLRKILEER
                     GYDYEDF"
     gene            complement(6188..8884)
                     /gene="ppc"
                     /locus_tag="AC1PIV_000888"
     CDS             complement(6188..8884)
                     /gene="ppc"
                     /locus_tag="AC1PIV_000888"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008964 - phosphoenolpyruvate carboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA];
                     GO_process: GO:0015977 - carbon fixation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HIP6611923.1"
                     /translation="MAIQKLENYNNKEAIREEVTILTSILEEVAAQMMPAETFAKIVE
                     LSQLSRQDDYQALIAIISQLNNDELAVISRYFAVLPLLINISEDVDLAYEINHQNNID
                     QDYLGKISTTIDMVSKQENAAEILEKLNVVPVLTAHPTQVQRQSMLDLTKHIHELLRR
                     YRDVKLGLLNKNKWEDELRCYIEIIMQTDMIREKKLKVTNEITNVMEYYNSSFIKAVT
                     KLQREYKRLAAEKGIVLNNPRPITMGMWIGGDRDGNPFVTAETLKLSALTQCEVIMNY
                     YDEQLYKLYRNFSLSTSIVNVSTAVKMLADLSEDSSVYRENEPYRRAFHYIQMKLANT
                     RDYLVHNKPSDVRYSNVAEFKADLLAIKQSLVENKSMALLKGDFTELLEAVEAFGFYL
                     ASIDMRQDSSIHEASVAELLASARIVEDYSSLSEEAKCHVLLKQLETDPRILSATHMP
                     KSEQLEKELAIFAAARELKDKLGEEIIKQHIISHSESVSDLLELAVLLKEVGLVDVDK
                     ARVQIVPLFETIEDLDNAPDTMRQYLQLDLAKRWIAGNKYYQEIMLGYSDSNKDGGYL
                     SSGWTLYKAQNELTQIGQDYGVNITFFHGRGGTVGRGGGPSYDAITSQPFGSIKDRLR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSATLDRMVTQMITDPNEIDGYRETMDEIVSDS
                     YRIYRDLVFNNPHFYDYFFAASPIREVSSLNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QNRVMLPGWYGVGSSFKRFIDKHPDNLSKLQKMYESWPFFRSLLSNVDMVLSKSNMNI
                     AFEYAKMCESEEVRNIFHVILDEWQLTKEIILSIEQNDELLAELPFLKASLDYRMPYF
                     NVLNYIQIELIHRLRRGELSKEQENLIHITINGVATGLRNSG"
     gene            complement(8905..10119)
                     /gene="ftsW"
                     /locus_tag="AC1PIV_000889"
     CDS             complement(8905..10119)
                     /gene="ftsW"
                     /locus_tag="AC1PIV_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division peptidoglycan polymerase FtsW"
                     /protein_id="HIP6611924.1"
                     /translation="MKIDKRQLLNYSILIPYLILSVIGLVMVYSTTSATQIINGGNPF
                     RTVINQAGFWIVSLVAIYTIYRMKLSFLRKKAVIYSVILVEVFLLAISRLFPPINGAH
                     GWIPLPIAGTLQPAEYLKLIIIWYLAHEFAKQQADIRTYDYVSLIKGSWIPKEFTDWR
                     VVSLLLLGLVATLPDLGNATIIVLIMVVMISVSGIAYRWFSTAVLGIVAASTVILGTI
                     RILGVETVEKIPLFGYIARRFAAYFDPFGNATNSGLQLTHSYYAMSNGGWLGRGLGNS
                     IEKKGYLPEAHTDFAFSIVIEELGFVGASLILALLFFLIIRIIIVGVRARSPFNAMMA
                     LGMAGMLLIQTFVNIGGISGIIPATGVTFPFLSQGGSSLLIISIGIGFVLNIDASEKR
                     RLIEEEIERTLI"
     gene            complement(10256..10621)
                     /locus_tag="AC1PIV_000890"
     CDS             complement(10256..10621)
                     /locus_tag="AC1PIV_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HIP6611925.1"
                     /translation="MKKISIMLMVVFSLFLAACTNTTEKQNNSAIEVTLQITTKDKEN
                     RQEVTAEEGDSVMDVLKEHHDIVEDNGLITEIDGVSQDTSTNTYWMYKVNGQMADKGA
                     KDLTVANGDEIEFYLETFE"
     gene            complement(10618..11037)
                     /locus_tag="AC1PIV_000891"
     CDS             complement(10618..11037)
                     /locus_tag="AC1PIV_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase YidC"
                     /protein_id="HIP6611926.1"
                     /translation="MHDKSEKVRRVSQLVVLSYFSLLESWILMILVMVGSGLLFGFGT
                     VVLWQVLSFAFIQFIWWLAIGPFIKKENIPLWLQSLLAGILVFLYGLTISFLSATQFG
                     TSPIVFWLNGLVFDSLHATSTVLFYPIIDYIFRRFYK"
     gene            11150..12004
                     /locus_tag="AC1PIV_000892"
     CDS             11150..12004
                     /locus_tag="AC1PIV_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HIP6611927.1"
                     /translation="MRKKLNPMIVVGFFLSFFALIFITGVTGNTVNKTEVANEPAVTQ
                     SNTSTSSKTTNSSSSYYIANALEMKPIIDVSAWQRPSEIDYDTLSKNISGAIVRIQSG
                     SHTKNENTATDKNGLDKSFDTHIKEFQARNIPVAVYAYVTGNSIENMREEARSFYKAA
                     NKYKPTFYWLDVEEYTMDDMNAGVEAFRKELETLGAKNIGIYVGTYFMEDHSINVDKF
                     DAIWIPTYGDDSGYYNAAPNTDLNYDLHQYTSRGYVNGFEHHLDLNIITTLKDPNEVY
                     QKLFTTPE"
     regulatory      12028..12123
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            12182..12730
                     /gene="thiT"
                     /locus_tag="AC1PIV_000893"
     CDS             12182..12730
                     /gene="thiT"
                     /locus_tag="AC1PIV_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015234 - thiamine transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015888 - thiamine transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HIP6611928.1"
                     /translation="MPTSKLPILAEVAIFSAIALVFDKIPLFTMPQGGSVSLVMLPIL
                     LLALRHGLGVGVLTGGIVGTIQLFYGGYFLNVFQVFLDYAFSYAGIGLAGLVAPTLSK
                     QNNLKNATLIITLASFLGGSIRLLATFLSGIIFYADYAPDGMPVWFYSFTYNISYILP
                     STAIASILLILLYRARPGFYNL"
     gene            12833..13675
                     /locus_tag="AC1PIV_000894"
     CDS             12833..13675
                     /locus_tag="AC1PIV_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HIP6611929.1"
                     /translation="MASWISRIIKGMIIALGFILPGVSGGVLAAILGIYERLIGFLAN
                     IRKDFKENFLYFVPVGIGGILGIALFSFPVEFLLQHFQVPVLWAFAGAIVGTIPSLLK
                     ESTQKSKRDSIDLAWLIGTFIISGLLLYNLSDLVGTLPATFASFVLAGALIALGVLVP
                     GLSPSNLLLILGIYTPMLNGFKSLDLFGTFLPIAIGGVLAMVAFSKAMDHALKVYHSR
                     VYHFIIGIVSSSTLLILIPQASNKESISYAGANFVTWIAAIVLFILGAWLGLWMSKLE
                     EKYK"
     gene            13675..14157
                     /locus_tag="AC1PIV_000895"
     CDS             13675..14157
                     /locus_tag="AC1PIV_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA deacylase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HIP6611930.1"
                     /translation="MAKKVKIKKTLVDQILDKAKINHDSLVLNAFEGQLPPGIEEHEI
                     YKTLALTGDKTGPIIGIIPITEHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNFPIYIDQSALELGHLIVSAGEIGRSIRIDSQVLADFVKADFADLIEGRD
                     "
     gene            14160..14786
                     /locus_tag="AC1PIV_000896"
     CDS             14160..14786
                     /locus_tag="AC1PIV_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HIP6611931.1"
                     /translation="MKIYFVRHGKTEWNLEGRFQGYSGDSALLPESYQDLEKLGKYLA
                     EIPFDAIYSSDLQRAHSTAVEIAKANHHCQTVLTTQQLREWNFGTLEGSKMAIFRAIY
                     PKQAWALKHNLALFNNDLFEAESVRQVTQRMVDFVQSLKGQDMETVLIVSHGAFLTAS
                     IHRLLGFPPAQLRHRGGLDNASVTILETSDFENFTELAWNDTSYKAKQ"
     gene            14889..16379
                     /gene="lysS"
                     /locus_tag="AC1PIV_000897"
     CDS             14889..16379
                     /gene="lysS"
                     /locus_tag="AC1PIV_000897"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HIP6611932.1"
                     /translation="MSTEHFEELNDQQIVRREKMTALAEQGIDPFGKRFERSANSAEL
                     KAQYEDKSKEDLEELGQTAIIAGRIMTKRGKGKAGFAHIQDREGQIQIYVRKDDVSEE
                     NYEIFKKADLGDFIGVEGDVFKTNVGELSIHARKLTHLSKALRPLPEKFHGLTDIETR
                     YRKRYLDLITNRESFDRFVTRSKIISEIRRYLDGLGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADYQDIMDLTEGIIQHTAKAVVGDGPVTYQGTEIAIHEPFKRIHMVDAIKEQTGVD
                     FWQEMSFEEAKALAAEHKVPVEKHHTEVGQIINSFFEEYVEATLIQPTFVYGHPVAVS
                     PLAKKNDEDPRFTDRFELFIMTKEYGNAFTELNDPIDQLERFEAQAKAKELGDDEATG
                     VDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(16967..18031)
                     /locus_tag="AC1PIV_000898"
     CDS             complement(16967..18031)
                     /locus_tag="AC1PIV_000898"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HIP6611933.1"
                     /translation="MVELGISTFGETTPLEKTGETYSHDERIRQLVKEIELADAVGLD
                     VYGIGEHHREDFAVSAPEIVLAAGAVNTKHIKLTSAVSILSSMDPVRLYQQYTTIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLHDYEELFDEKLDMLLEIGKETNLKWDGHFTQSV
                     DNKPVYPRPVQEDFPIWVATGGNVESTIKIAKKGLPIVYAVIGAGAHRFKPLVDAYRK
                     VARNSGHDPKKTKVAAHSWGWIADDHDKAVEEYYHPTKVITDNIAKDRPHWSEMTKAQ
                     YLYSLTDEGATIVGDPKRVAEKIIKTIETLDLDRFFLHLPIGSMPHEDVLRAIELYGK
                     EVVPIVRDYFAKKEENQSQD"
     gene            complement(18157..19404)
                     /locus_tag="AC1PIV_000899"
     CDS             complement(18157..19404)
                     /locus_tag="AC1PIV_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIP6611934.1"
                     /translation="MENWKFALKSIMAHKMRSLLTMLGIIIGVAAVVIIVAMGTGVAK
                     SIEKSLAGDQNNVQVYFTAFSSSGTAFGPFGTASTEEPILEEEPDLTDSTLKGLLEID
                     GVSNYYSSISNIAEVRSGNKKAENVTITGVSQNFFAVKEYEILAGRQFTANDYSRFSR
                     MIMLDTALAEKLFGSIENSLNQTISVNSNAYLVIGVYKDPKAGTAIYGMNSGGNAVMT
                     NTQLAAETGMKENSQIFVHVEDVTRATEVGKAAADYLTKATGLKEARYEIYDMSAMLE
                     EFKSQMSGVTLFIGAVAGISLLVGGIGVMNIMLVSVTERTREIGLRKALGATRGNILI
                     QFLIEAMVLTTLGGAIGLAIAQTIVFLLNVSKALGERIAAEISIPVVLGSLAFSAVVG
                     IVFGVLPANKASKLDPIEALRYE"
     gene            complement(19405..20100)
                     /locus_tag="AC1PIV_000900"
     CDS             complement(19405..20100)
                     /locus_tag="AC1PIV_000900"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIP6611935.1"
                     /translation="MKNQLIRLTSINKSYKNGDQELRVLKNIDLEVEEGEFLAIMGPS
                     GSGKSTLMNIIGLLDRFSSGNYWLEGEEVSQLSEKKLAQVRNDQIGFVFQQFFLLSKL
                     NALQNVELPLIYAGVPSSKRKELAKQYLEKVELAERMTHLPSELSGGQKQRVAIARAL
                     VNTPAIILADEPTGALDTKTGEQIMQLLTELNNEGKTIIMVTHEPEIAAYAKRKIVLR
                     DGVITEDSRREGV"
     gene            complement(20081..21238)
                     /locus_tag="AC1PIV_000901"
     CDS             complement(20081..21238)
                     /locus_tag="AC1PIV_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HIP6611936.1"
                     /translation="MLKTKKAKIALFGGLGVVAVALVGGALIFSNMLTSPSSSEDVAM
                     SMTYTVAKEGSIASSTLLTGTITAADEQYVYYDPSKGDLSEVLVAPGAKVEVGTPLIR
                     YDATELQSALDTAVRGRDKIGRQIADLRTNGQTVQTTGDAETDAAATATAQRSVDMQL
                     ADLNDSYADAQAAVDKAYTALTEATVTSTVAGTVVEVNKAVSKNSTSSQTVVHIVNQG
                     SLQVTGSLTEYDLANIAVDQEVKLTSKVYPDKTWTGKITYISNYPSSNQAGAATTGTS
                     GSGAKYPFKAALTSELGELKQGFSVNIEVVNTSKNILIPVSAVVPEEDKNYVWTLVDG
                     KAKKVEVTLGNADALNQEVTAGIAAGDKVITIPTPNLEDGKEVEANEEPAY"
     gene            21452..22801
                     /gene="gorA"
                     /locus_tag="AC1PIV_000902"
     CDS             21452..22801
                     /gene="gorA"
                     /locus_tag="AC1PIV_000902"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004362 - glutathione-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HIP6611937.1"
                     /translation="MKVFDIIAIGGGSGGIATMNRAAMYGAKAAVIEGSYLGGTCVNL
                     GCVPKKIMWYGSQVAEAIQHYGPEYGFTSQEVTFDFATLRKNREAYIERSRASYGNTF
                     NNNEVEVIQGFARFVDNQTVEVNGELIRAKHIVITTGAKPVVPAIPGSELGIVSDDVF
                     AWEELPSSVAVIGAGYIAVEMAGLLHGLGVQTDLFVRGNRPLRSFDTYIVDALMEEMQ
                     RTNLPLHTGKTPVSLEKTDDGQIQINFADGSNHIAQKVLWAIGRKPNIDKLNLKATSV
                     QLTSSGHISVNEYQETAVPGIYALGDVTGEKELTPVAIKAGRLLAERLFNNKPTAKMD
                     YTTIPTVVFSHPAIGTVGLTEDEAITQYGQDNVKVYTSAFTSMYTALENNRQMAKFKL
                     VTVGENEKVVGLHGIGYGVDEMIQGFSVAIKMGATKEEFDAVVAIHPTGSEEFVTMR"
     gene            complement(22851..23588)
                     /locus_tag="AC1PIV_000903"
     CDS             complement(22851..23588)
                     /locus_tag="AC1PIV_000903"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016812 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds, in cyclic amides
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclase family protein"
                     /protein_id="HIP6611938.1"
                     /translation="MTELLDIYRTLKSKTWVDLTHQINEKSPHFPALPALEKKALFTH
                     KDGFFVEQFTVVGQYGTHIDPPIHFVEGARYLDEIDLKDLLLPLYVIDKSAAVIENND
                     YEITKQDILDFEAEYGPIAPKSFVAFRSDLSKRWPSQDAIRNLDEDGVQRTPGWSHEA
                     LEYLIEERQVKAVGHETLDTDSGVSAAKHGGSLSEEYYLLSKDIYQLEVLANLDQVPP
                     TGALISIAFPHWEKASGSPVRAIAILP"
BASE COUNT         6974 a         5213 c         4473 g         6953 t
ORIGIN      
        1 gttcataact atgtacatgt tgatcatgag ctgatttata aacttatcaa tacaaaagaa
       61 tttcagcgac tacgccgcat caagcaacta gggactactt cctatacctt ccatggtggc
      121 gagcatagcc gcttttcgca ctgccttggc gcctacgaaa tcgccagacg gattactcaa
      181 aaatttgaag acaagtatcc acaaatctgg gatacaaatg agtccctact gaccatggtt
      241 gctgcgctac tccatgatgt cggacacgga gcctattctc ataccttcga gcgtctattt
      301 gatacagacc atgaggaaat gacctgtgct attattacta gtccagaaac ggaaatcaat
      361 gctctgttga aacaagtttc acctgagttt ccagacaagg ttgctagtgt tatcaaacac
      421 acctatccaa ataaacaggt cgttcaactc atttcgagcc agattgatgt tgaccggatg
      481 gattatctat tacgagattc ctacttcaca ggtgcgaact atggtgaatt tgacctaact
      541 aggatattac gtgtcattcg cccgacagaa aatggaattg ccttcaaaga atctggtatg
      601 catgcagtag aagactacgt tctcagccgc taccagatgt acatgcaagt ctattttcat
      661 ccagcaagcc gctctatgga agtcctattg cagaatttac tcaatcgtgc caaactacta
      721 tatactggtg aacaggagtt ttttgcacga acttcacctc ggctattacc tttttttgag
      781 catcgtatcc gtctaaccga ctacctcagt ctggatgatg gagttatgaa tacttacttt
      841 caatcatgga tagatggacc agatcgtata ttatctgact tagcccagcg ctatatcaat
      901 aggaaagtgc tcaaatccat cactttcaag gccgaagaag aggaagcttt ggaccgcctg
      961 cgtagcctgg tcgcagacgt cgggtttgac ccagaatact atactgctat tcaccacaac
     1021 tttgatttgc cgtatgacat ttaccgaccg aatgcagaaa agaaacggac tcaaattgag
     1081 atttatcgca aagatgaaac cttggtagaa ctatcctctc tatcaccaat tgtccattcc
     1141 ttatcaggca caatccatgg cgatagccgc ttctatttcc caaaagaaat gttagaagaa
     1201 acaggaattt tcgcacctca aatagctgat tttaacagcc acatacataa cgatcatttt
     1261 ataattggag aatcaaatga gcattaaact tgtcgccatc gatattgatg gtacactact
     1321 aaatagtcaa caccaaatta cagctgaagt acactcaaca atccaagaag caaaaaaagc
     1381 aggcgttaaa attgttattg ctactggtcg ccccatttcc ggtgttcaag caattttaga
     1441 agaactcaat cttacagaag caggtgacta cgtcatcact tttaacggtg gcttagtcca
     1501 agatgcagca actggtgagg atattgtcaa agataccttg acttatgagg attatctcga
     1561 catcgaatct gctgcccgta aactcaagct cccaatgcat gccagcacca aggaaggtat
     1621 ctatactgcc aaccgtaaca tcggtaaata caccatttac gaatccacac tagtaagtgc
     1681 acccattttc tatcgcactc ctgaagaaat ggctgacaag gaaatcatca aaacaatgat
     1741 ggttgatgag ccagaaattc ttgatgctgc tattccactt ctaccgacca tcttgactga
     1801 gaagtacaac gtagcaaaat cagcaccatt ttatttggaa atcaccccta aaactgttaa
     1861 caagggacaa gctatcattc atctagctga gaagcttgga ctaactatgg atcaaaccat
     1921 ggccatcggt gaccaagaaa atgaccgtcc aatgttggaa gttgttggta atcctgttgt
     1981 catggaaaac ggaaatcctg aattgaagaa aatcgccaaa tacattacga aatcaaatga
     2041 tgagagcggt gtagcccacg cttttagaga atgggtactg aagtagcctc ttaaaatatc
     2101 aaaaaagcat cgaattcaaa atccgatgct ttttgttatt agaagttcaa caaagccaag
     2161 aagctttctg cttcaagtga tgcaccacca acaagcgcac cgtcaacgtc tggacatgcc
     2221 atgtattcag caacgtttga tgggtttaca gaaccaccgt attgaacgcg aactttgtct
     2281 gcaacttctt gaccgaaatc agcagcaaca acgtcacgaa cagctttaca catgttttgt
     2341 gcatcatctt tagtagctga tttaccagta ccgattgccc agattggctc ataagcaata
     2401 acaagtgatg ctacttgatc agcagtcaag tctttcaaag ctgcagaaac ttgagcacct
     2461 acaaattcta ctgctttacc agcttcgtaa gtttcaagtg actcaccaca acagatgatt
     2521 ggagtcaaac cgttacggaa gattgcatga gcttttttat taatatcttc atcagtttcg
     2581 tggaagtaat cacgacgctc tgagtgaccg ataacaacat agttaacacc catttcagcc
     2641 aatacttttg gagatgtttc accagtgaag gcaccagcat cttcaaagta gcagttttga
     2701 gcagcaactt tcaattcaga atctttagcg aaccataaga gagcgttcaa atctacagct
     2761 ggagctgcga tagctgcttc aattttgtcg cctgcaggca attttcctgc aattgcctca
     2821 acgaaagctt gtgcttcttg aggatttttg ttcattttcc agttaccggc aatgattggt
     2881 ttacgtgaca tttcacttac ctcttctata tttattttac aaggtacatt atagcataaa
     2941 cttagctaag attaaagaat ttctgtgcat tttatgaata cttacagaaa aactctctac
     3001 ccgaaagtag agagttacaa ttaagttgtc tgactataat tgttatttct gggaactcaa
     3061 tcgaattaag cttcgatttc tgtaaccata cctgaaccaa cagtacgtcc accttcacgg
     3121 atagagaaag tagtaccttg ttcaacggcg attgggtgga tcaattcaac gtcgatagta
     3181 acgttatcac caggcattac catttcagta ccttctggca atttgattga accagttacg
     3241 tcagttgtac ggaagtagaa ctgtggacgg tagttgtcga agaatggagt gtgacgtcca
     3301 ccttcttctt tagtaaggat gtaaacttca cctttgaatt tagtgtgtgg gttgatagaa
     3361 cctggtttag agataacttg accacgttcg atttcatcac gttgtacacc acgaagaagc
     3421 acaccaacgt tatcgccggc aagaccttcg tcaagttgtt tacggaacat ttcaacacca
     3481 gtaacaactg ctttagattt ttcttcttga agaccaacga tttcgatttc gtcgttgaca
     3541 cgaacagtac cacggtcgat acgtcctgaa gctacagtac cacgaccagt gattgagaat
     3601 acgtcctcga ctggaagcaa caatggtttg tcagtgtcgc gttctggttc tggaatgtac
     3661 tcatcaacag tgttcatcaa ttccataacg atgtcttcgt acttagagtc accttcaaga
     3721 gctttaagag ctgaaccttg gataactgga agatcatcac ctgggaaatc gtattctgaa
     3781 agaaggtcac ggatttccat ttcaaccaac tcaagcaatt cttcatcgtc aaccaagtca
     3841 actttgttca tgaagacgat aaggtgttta acaccaacct gacgtgaaag aaggatgtgc
     3901 tcacgagttt gtggcattgg accgtcagtt gaagctacta caaggatcgc accgtccatc
     3961 tgagcagcac cagtgatcat gtttttaacg tagtccgcgt gtcctggagc gtcgatgtga
     4021 gcatagtgac gtttttcagt ttcgtactca acgtgtgcag tgttgatagt gataccgcgc
     4081 tcgcgctctt ctggagcagc atcgatagac gcatagtctt taggttggtt aactgatgaa
     4141 ggcaagcgac gtgccaatac agttgtgata gctgctgtca aagtagtttt accgtggtca
     4201 acgtgtccaa ttgtaccaat gttaacgtgt ggtttactac gatcgtattt ttcttttgcc
     4261 attttggtaa aagcctccaa taaaatatat tttatagata gacagtaggc aatacagtct
     4321 aactttacct tactattcta tcaaattgta gcagaattgc aagcattttc tatcgttttt
     4381 tattttatcc attttctgca agggctatta gcttcgctta taactttttt tatcatccca
     4441 ttttaaccta ttactcaact aaaaacacct catttccgta agaatattga tgttaccata
     4501 gctacaaggt gccacaaata cgagaccact gcgacagacc tttctccatt cagttatcct
     4561 acgactccct gacaagcctc ttgctatagg tgttgaaaat atattgacta ttttcactta
     4621 atgatgcagt tgataataag gctgaatagg aatggacgcg ccaatactag aagaataaat
     4681 ccagtccttg ccttccaact gggcaaagtc ttctgctttt cctgttagga taatgcctgc
     4741 aaattctagc ttatcaatct cttcttgttt agtaaagtct gtatcgccaa atttgtcaac
     4801 aaaggcttgc aagtcatcca caggtatgtc cagatactgc gctcgtttct gatctcccga
     4861 ttctaagaac tctttcataa agtccatacc tgtcatatag tctccaggca tatccgaaaa
     4921 gactagttga atatcctctg gatctaaccc caaaagctgc tctggacgat agtaatgggt
     4981 attctgcttc ccttctgtcc ctatccaata ccaattttgc ttgagattgc tgggaatcat
     5041 ttgcttgatt tctgccaaac tatacttctt atcaaaggaa atagccactt ctactagctg
     5101 cccactcatg tctttaagat aatgcaattc attggcaatg tcttgaacac tccaaacgga
     5161 cttttttcta ttgtaaaaaa caggtatctt ggtattggtt gtgaaatcat atagatattt
     5221 gaaggtattc ccgggtatat gctgagcaaa atcatagtga cgatcaaaca ggtcatagta
     5281 aatttcgtgc tgaccaaaag ccataggaac accagctaga tccttatata aattgcagta
     5341 aagtttccca gaaacataac tcgtgctttg gattttaata ccgtcatgtt ttatatttgg
     5401 ataagagatt tccattaaaa taatttgttt ccaattctca ctaccttctc gtgcaccgac
     5461 aattattttt acagtttgaa tgccaatcaa caataagata aagccgatga acgatgatag
     5521 tccaactgtc ttccataaat ttttccgctt actctttttt gtcacctctt caaaagtctt
     5581 catagtcata tcctctctct tctagtattt tccttaactg cttgcgtcct cggtgaaggc
     5641 tgattttcac ccaactttga ccagcaccta aaatatgcgc aatctctttg atactcatat
     5701 cttggaagta gtataagtca atcacttgct ggtatttttc tggcaggtct gcaacagctt
     5761 gatagagttc ctcataatct tcttggtcat agaccaaaaa attttcaggt gtaaaaaact
     5821 ccttttgtaa aatttcatgg tagcgcttgt ctcgcctgta tttgtcaatg taagcccgaa
     5881 ctgcagaacg gtaaagccaa gctcttagtt tttcgaaagg aaggacaagc tctgcttcta
     5941 aaattttcac tagtatatcc tgtgcgatgt cctgactatc tgcatagttg gcgccagatt
     6001 tttgtagata gtaggaaatc tcctcagcaa taccaatgac ttctttttca tattgatcaa
     6061 gtttgatact catctcctcc tttcactaat agaacgaata agggatgatt tggttacact
     6121 ttcttatgat tattatatat ttttatcagc aaaaaaaaca acctccgaag aagttgtttt
     6181 atgcctatta acctgagttg cgcaaacctg tcgccacacc attgatggta atatgaatga
     6241 gattctcttg ttctttgctc aattctccac gacgaagacg atgaattaat tcaatctgaa
     6301 tatagttgag cacattaaaa taaggcatgc gataatcaag actagctttt agaaacggta
     6361 gttctgctaa aagctcatca ttttgctcga ttgacaaaat aatttctttg gtcaactgcc
     6421 attcatctaa aatgacatgg aagatatttc gtacctcttc gctttcacac attttagcat
     6481 attcaaatgc gatattcata ttggatttag acaataccat atccacgttt gatagaagtg
     6541 aacggaagaa tggccaagat tcatacattt tttgtaactt agacaaatta tcagggtgct
     6601 tatcaataaa gcgtttgaaa cttgaaccaa ctccatacca ccctggcaac atgacacggt
     6661 tttgtgacca agagaatacc catgggatcg cacgcaaacc accgatttct gtgatggttt
     6721 ttcgagccgc aggacgtgag ccaatgttca gacttgatac ttcacgaatt ggactagcgg
     6781 caaagaaata atcataaaaa tgtggattgt tgaatacaag atctctataa atacgatagc
     6841 tatctgatac aatttcatcc atggtttcgc gatagccatc gatttcattt ggatcggtaa
     6901 tcatttgtgt gaccatacgg tcaagcgttg cagataccag catttctaaa ttatagtagg
     6961 ctgcgtcttt gttaccgtat ttattgccta tcacttcgcc ttgttctgtc aaacgaagcc
     7021 ggtccttgat ggaaccaaat ggctgagatg taatcgcatc ataggaagga ccaccaccac
     7081 gaccaacagt acctccacga ccgtggaaga aggtgatgtt tactccgtag tcttgaccaa
     7141 tttgcgtcaa ttcattctgt gctttgtaga gtgtccagcc ggaggatagg tagccaccat
     7201 ccttgttgga atctgagtag ccaagcatga tttcttggta gtatttattg cctgcaatcc
     7261 aacgtttcgc taaatctaat tgcagatatt gacgcatggt atcaggtgca ttatctaaat
     7321 cctcgattgt ctcaaaaagt ggaacaatct gaacacgggc cttatcgaca tctactagac
     7381 caacttcttt taataggaca gctaattcca gtaaatcaga aacactctcc gagtgtgaaa
     7441 taatatgttg cttgatgatt tcctcaccta gcttatcttt caattcacgt gcagcagcaa
     7501 agattgccaa ttctttttct aattgttctg actttggcat gtgcgttgca gaaagaatgc
     7561 gtggatctgt ttccaactgt ttcaaaagaa catggcattt agcttcctca gataaactgg
     7621 agtagtcttc tacgatacga gcagaggcca ataactccgc aacacttgct tcatgaatag
     7681 aagagtcttg gcgcatatcg atactagcta ggtagaaacc aaacgcttca accgcttcaa
     7741 gcaattctgt aaaatcacct ttcaatagcg ccatagattt attttcgacc aaagattgtt
     7801 tgatggctaa taaatcagct ttaaactcgg ctacattact atagcgaaca tctgacggct
     7861 tattgtgaac taaataatct cttgtatttg caagtttcat ctgaatatag tgaaaagcac
     7921 gacgataagg ctcattttca cggtagacag aactatcttc agataaatcc gccagcatct
     7981 taaccgctgt agatacattt acaatggaag ttgagagcga aaaattccga tagagtttat
     8041 agagttgctc atcgtaataa ttcataatga cttcacactg agtcaaggct gacagcttca
     8101 aggtctctgc agtaacaaat ggatttccat cacggtctcc cccaatccac atacccattg
     8161 taattggacg aggattattt aagacgattc ctttctcagc ggccaaacgt ttgtattccc
     8221 gctgcaactt agtgacagcc ttaataaagg aagaattgta atactccata acgtttgtga
     8281 tttcgttggt taccttcaac ttcttctcac gaatcatatc cgtctgcatg ataatttcaa
     8341 tgtaacaacg gagctcatct tcccatttgt ttttattgag caagcccaat tttacatcgc
     8401 gataacgacg aagcaactca tgaatatgct tggttaaatc aagcatagac tggcgttgaa
     8461 cctgagtagg atgggctgtc aagactggaa caacattcaa cttttcaagg atttcagctg
     8521 cattttcttg tttggaaacc atatcaattg ttgttgaaat cttaccaaga taatcttgat
     8581 caatattgtt ttgatggttg atttcatagg ccaagtcaac atcttctgat atattaatca
     8641 aaagtggcaa aacagcaaag tatcgagaaa taaccgctag ttcatcatta ttcaactgac
     8701 tgataatagc aatcaatgcc tgataatcat cttgacgaga caattgagat agttctacaa
     8761 ttttagcaaa agtctctgca ggcatcattt gggctgctac ttcttccaaa atagatgtta
     8821 gaatcgttac ttcttcacgg attgcttcct tgttgttata gttttctaat ttttgaatag
     8881 ccatctccta cctctttcct atctctaaat tagcgtacgc tctatttctt cttcaattaa
     8941 tcgacgtttt tcactagcat caatattcaa aacaaaccct atcccgatgg aaataatcaa
     9001 gagactcgat ccaccctgtg acaagaaggg gaaagttacc cccgttgcag gaataattcc
     9061 tgaaattcct ccgatattga caaatgtttg aatcagaagc atacctgcca ttccaagtgc
     9121 catcatcgca ttaaatggac tacgagcacg gacgcctaca ataataattc gaataatcaa
     9181 aaagaacaat aaggctagaa ttaaactagc tccaacaaaa ccgagttctt caatgacaat
     9241 cgaaaacgca aagtcggtgt gggcctctgg tagatacccc tttttctcaa tcgaatttcc
     9301 caaaccacgt ccaagccatc caccgttact catcgcatag taagaatgag tcaattgaag
     9361 acctgagttg gtggcattac caaatggatc aaaataggca gcaaaacgac gagcaatata
     9421 accaaagagc ggaatttttt ccaccgtttc tacacccaaa atacgaatcg tccctagaat
     9481 aactgttgag gcggccacaa ttcctaaaac cgctgttgaa aaccagcgat aggcaatccc
     9541 actcacacta atcatcacga ccataatcag cacaataatc gtcgcatttc ccaagtccgg
     9601 cagtgtcgca actagaccta ggaggagcag actgaccacc cgccaatctg taaactcttt
     9661 cggaatccaa cttcctttaa tcaacgatac atagtcataa gtccgaatat ccgcctgttg
     9721 ttttgcaaac tcatgtgcca gataccaaat gataattaat ttcaaatatt ctgccggctg
     9781 caaggttcct gcgattggca gaggaatcca tccatgagcc ccgttaatcg gaggaaacaa
     9841 ccgagaaata gctaacagaa atacttctac caaaataacc gaatagataa cggctttctt
     9901 gcgtaaaaaa cttaatttca tacgataaat cgtatagatt gctaccaagc tgacaatcca
     9961 gaatcctgcc tggttaatca ctgttctaaa tggatttcca ccattaataa tttgcgtagc
    10021 actggttgtc gaatagacca tgaccaaccc aatcaccgat aagatgagat agggaatcag
    10081 tatggaataa ttcaacaact ggcgtttgtc aatcttcatt gcttatccaa ccttcttcga
    10141 gtatagctct tattatagca tactttgtat aaaaatactt atcactttct aagttgctct
    10201 gcaaacattc ggaactgact tttgtcgaca agaaaaaggc cgaagccttt catatctatt
    10261 caaatgtttc aagataaaat tcaatttcat ccccattcgc aactgtaagg tctttcgccc
    10321 ctttatcagc catttggcca ttaactttat acatccagta tgtattggta ctcgtatctt
    10381 ggctaacacc atcaatttct gttatcaaac cattgtcttc tacaatgtca tgatgttctt
    10441 taagcacatc catgacacta tcaccttctt ccgcagtgac ttcctgacga ttctctttgt
    10501 ccttggttgt aatctgcaaa gtgacttcga tagccgagtt gttctgtttc tcggtagtgt
    10561 ttgtacaagc agccaagaag agcgagaaga caaccatcaa cataatacta atttttttca
    10621 tttataaaat ctcctaaaaa tataatcaat aattggataa aacaaaactg ttgaagtagc
    10681 gtgtaaacta tcaaagacta aaccattaag ccaaaagacg ataggagaag tcccaaactg
    10741 tgtagcagat aaaaaactta tcgttagccc atacaaaaag acaagaatcc ccgccagaag
    10801 actctgtagc cacaagggaa tgttctcttt tttgataaaa ggaccgattg ccaaccacca
    10861 tataaattgg ataaaagcaa aactaagaac ttgccacaaa acaactgtgc caaatccaaa
    10921 aagcaagcca ctccctacca tcactagtat catcaatatc cagctctcca gcaaactgaa
    10981 ataggacaga acaactagct gactaacacg tcttactttt tcacttttgt catgcatacc
    11041 aatttagcct accctattcc ctttattatg tcaagttcag ataatctttt actatttctt
    11101 gaatcgtatt tttttgattt tttcatgatt ttacggtaga attgaggaga tgagaaagaa
    11161 actaaatccg atgattgttg ttggtttttt cctatccttc tttgctctta ttttcatcac
    11221 tggggtgact ggaaatactg taaataagac ggaggtagct aacgaacccg cagtcacaca
    11281 atcaaacacc agtacaagtt ctaaaacaac aaattctagt tcgagttatt acattgcaaa
    11341 tgcgctcgaa atgaaaccta tcatcgacgt ttctgcttgg cagagaccgt ctgaaattga
    11401 ctacgatacc cttagcaaaa acatttctgg cgccatcgtt cgtattcaaa gtggatcaca
    11461 cactaaaaac gaaaatactg cgactgataa aaatgggtta gataaatcct ttgataccca
    11521 tattaaagaa tttcaagcaa gaaatatacc tgttgctgtc tatgcctatg tcacgggaaa
    11581 tagtattgag aacatgcgag aggaagctcg aagcttttat aaggccgcaa ataagtacaa
    11641 gccaaccttc tattggttag acgtcgaaga atataccatg gatgatatga atgctggagt
    11701 ggaggctttt cgaaaagagt tagaaactct cggcgctaaa aacattggaa tttacgtcgg
    11761 aacctatttc atggaagacc acagcatcaa tgtggataaa tttgacgcta tttggattcc
    11821 tacatacggt gatgattctg gctactacaa tgccgctcca aatactgact tgaactacga
    11881 tcttcaccaa tatacctcac gtggttatgt aaacggcttt gagcaccacc tagacctcaa
    11941 cattattact accctgaagg atcctaatga agtttatcag aaactattta caacacccga
    12001 ataaaatgat acaatttcac taattacata tacacaaagg agtgcttcgg ctgagatcgc
    12061 aactgcgaaa tcctcgaacc tgatctagtt aaaactagcg taggaattgt gtgctttata
    12121 gaatgatact atactctgct ataaacactc ctttgttgac catctacaaa ggagtctttt
    12181 tatgcccaca tcaaaattac ccatcctagc tgaagttgct atcttttctg ccattgccct
    12241 cgtctttgac aaaatcccgc tctttacaat gccccaaggt ggatctgtgt ctttagtcat
    12301 gcttccaatc ttactgcttg ctctgcgcca cggactaggg gtaggagttc ttactggtgg
    12361 tattgtagga accattcaac ttttctacgg tggctacttc ctaaacgttt ttcaagtttt
    12421 tctcgactac gcattttctt acgccggaat tggtttagca ggtttagtgg cacccaccct
    12481 atccaaacaa aacaatctaa aaaatgctac tctcatcatt actctggcta gttttctagg
    12541 aggaagcatc cgattgttag ccaccttctt atcaggaatt attttctacg cagactacgc
    12601 tccagatggt atgcctgtct ggttctattc ctttacctac aatatcagct atattcttcc
    12661 ttccacagca attgcctcta ttctgctcat tttactctat agagcaagac caggttttta
    12721 caatctttaa ccaaaactgc ctgctggatt ttatctaaca ggcagtcttt ttaattattt
    12781 ttacttgctt tatgctataa taggaacgtt ataatacatt ttggaggaaa ttatggcttc
    12841 ttggatttca agaattatta aaggtatgat tatcgcactc ggctttatct tacctggtgt
    12901 ctctgggggg gtactcgctg ctatcctcgg aatctatgag cgactaattg gatttttagc
    12961 aaatattcga aaagatttca aggaaaactt tctttatttt gttcctgtag gaattggtgg
    13021 aattttggga atcgcacttt tctctttccc tgtagaattt ttattgcaac atttccaagt
    13081 cccagttttg tgggcctttg cgggagcaat cgtgggaacg attcctagcc tacttaaaga
    13141 atcaactcaa aagagcaaac gagatagcat tgatttggct tggttgattg ggacattcat
    13201 tatttctggc ctcctacttt acaatttgag cgatcttgtc gggacacttc cagctacttt
    13261 tgctagtttt gtattggcag gtgccttgat tgctttaggg gtacttgttc ctggactcag
    13321 cccttcaaac ttactattga ttttgggtat ctacacgcca atgctaaatg gtttcaaatc
    13381 acttgatcta ttcggtacct tcctaccaat cgcaatcggt ggcgttcttg caatggttgc
    13441 attttcaaaa gcaatggacc acgctctgaa agtataccat tcacgtgttt atcactttat
    13501 tattggtatc gtttcatctt ctactctcct aattttgatt ccacaagcaa gtaataaaga
    13561 gtctatttcc tatgctggcg ctaactttgt tacatggatt gctgctattg tcctatttat
    13621 actaggagca tggttagggc tttggatgag taaacttgag gaaaaatata aataatggca
    13681 aaaaaggtta aaataaagaa aaccttggtg gaccaaatat tggacaaggc taagatcaat
    13741 catgatagcc ttgttttaaa tgccttcgaa ggtcaacttc caccaggaat tgaagaacac
    13801 gaaatttaca aaacactggc attaactgga gataaaactg gaccaattat cggcattatc
    13861 ccaatcacag aacacctgtc tgagaaaaaa ttagccaaga tctctggcaa taaaaaagtg
    13921 agtatgattc cgcaaaagga cttggaaaag acaactggct acatccatgg tgccaacaat
    13981 cccgtaggca ttcgtcagaa gcataatttc ccaatctaca ttgatcaatc tgcccttgaa
    14041 ctcggtcact tgattgtctc tgctggagaa attggtcggt cgattcgaat tgacagtcag
    14101 gtattagctg attttgtaaa agctgacttt gccgatttga tcgaggggag ggactagact
    14161 tgaaaatcta ctttgtccgt cacggtaaga ccgaatggaa tttggaggga cgctttcaag
    14221 gctattctgg agattcagct ctcttgcctg aatcttatca ggatttagaa aaactaggca
    14281 aataccttgc tgaaatcccc tttgatgcta tttattctag tgatttgcag cgcgcacata
    14341 gcactgccgt agaaattgcc aaagccaatc accattgcca aaccgttcta accacgcaac
    14401 aattacgtga atggaatttt ggaacgctgg aaggaagcaa gatggcaatt tttcgtgcca
    14461 tctatcccaa acaagcctgg gcactcaaac ataatctagc actttttaac aatgacttat
    14521 ttgaagctga gagcgttcgc caggtaactc aacgaatggt ggactttgtc caatcgctga
    14581 aagggcaaga catggaaaca gtcctcatcg tcagccatgg tgcttttcta accgcttcta
    14641 tccatcgcct acttggtttt ccaccagccc aactgcgtca ccgaggtggt ttggataatg
    14701 catcggttac tattttagaa acaagcgatt tcgaaaactt tacagaatta gcttggaatg
    14761 ataccagcta taaagcaaaa cagtagaatt ttctgctgtt ttttcctatc ctattagcaa
    14821 tttatactga ttttttctct cttctatgat aaaatagaaa taacagactt tggaggaata
    14881 aaatttttat gtcaactgaa cattttgaag aattaaatga ccaacagatt gtccgtcgtg
    14941 agaaaatgac ggctcttgct gaacaaggca ttgacccatt tggaaaacgt tttgagcgtt
    15001 ctgccaactc agctgaattg aaggcccagt acgaagacaa atcaaaagaa gacttggaag
    15061 aattagggca aacagcaatc attgcaggtc gtattatgac caagcgtggt aagggtaagg
    15121 caggttttgc tcacattcaa gaccgcgaag gccagattca gatctacgtt cgtaaggatg
    15181 atgttagcga agaaaactat gaaatcttca aaaaagcaga cctaggtgac tttatcggtg
    15241 tcgagggaga tgtcttcaag acaaacgttg gtgagttgtc tatccatgct cgcaagttga
    15301 ctcacttgtc taaagcgctc cgcccattgc cagaaaaatt ccacggtttg acagacatcg
    15361 agacccgcta ccgcaaacgt tatttggact tgattactaa ccgcgagagc tttgatcgct
    15421 ttgtgacccg ctcaaaaatt atctcagaaa tccgccgtta ccttgacgga cttggtttct
    15481 tggaagtgga aacaccagtt cttcacaacg aagctggtgg tgctgcagct cgtccattca
    15541 tcacccacca caatgcccaa aacattgaca tggtccttcg tatcgcgaca gaactccacc
    15601 tcaaacgcct gattgtcggc ggtatggaac gcgtttatga aatcggccgc atcttccgta
    15661 acgaaggtat ggatgcgacc cacaaccctg agttcacttc cattgaggtt taccaagctt
    15721 atgcagacta ccaagacatc atggacttga ccgaaggtat tatccagcac actgccaagg
    15781 ctgttgtcgg tgatggtccg gtgacttatc agggcactga aattgctatc cacgagccat
    15841 tcaagcgtat ccacatggtt gacgctatta aggaacaaac tggcgtggac ttctggcaag
    15901 agatgagctt cgaggaagca aaagcccttg cagctgagca caaggtccct gtggaaaaac
    15961 accatacaga agttggtcaa atcatcaaca gcttctttga agaatacgtt gaagcaactc
    16021 ttatccaacc aacctttgtc tatggtcacc cagtagccgt atctccactg gctaagaaaa
    16081 acgatgaaga cccacgcttc acagatcgct tcgagctctt catcatgacc aaggaatacg
    16141 gaaatgcctt tacagaattg aacgacccaa tcgaccaatt ggaacgcttt gaagcccaag
    16201 ccaaggctaa agaactcggt gacgacgaag cgacaggcgt tgactacgac tacatcgaag
    16261 ccctcgaata cggtatgcca ccaacaggtg gacttggaat cggtatcgac cgcctctgca
    16321 tgctcttgac agatacaact actattcggg atgtgttgct attccctact atgaagtaag
    16381 caagagtagc ttgctaggtt tgttttcact aggatgttca aatcgctctc cagtttcttg
    16441 gcgattggct gaaaaggtct accagacctt ctcactcccg acgatgaaat aaaaattaca
    16501 aactgtttaa caccgttacg taaaacactc ttggaaattc caagagtgtt tttgcattca
    16561 aaaatcccaa ccacatggtc aggtttttca ggagattatg aaaaatattt aggattggga
    16621 gtgggaaaga actcaaataa tcatagagag ttcgtcaaca agttcatatt tccagttgtt
    16681 gagctgaaac agtctatccc cagactgttt cactcccacc cccgcacagc tccaaaggtt
    16741 tggggaacct ttggaggtcg gagatagagc gaacagagtt cgctacagaa cagtcagaat
    16801 agtgactgtt ggaggtcgga aataaagcga acaccgttcg cttcagccgt agaggaagat
    16861 gtggagtgta aaacacgaac aaatcttcca atcaaccact gcgctgagat gttgactcca
    16921 ctttagagaa gtgaggctat tataacgtcc catccttttt atctcatcag tcctgggact
    16981 gattctcttc tttttttgca aaataatctc ggacaattgg cacaacttct tttccgtaga
    17041 gttcgatagc acggaggaca tcttcatgtg gcattgagcc gattgggaga tggaggaaga
    17101 aacggtccaa gtcaagtgtt tcaatagtct tgataatttt ttcagcaact cgttttggat
    17161 ctccgacgat ggttgctcct tcgtctgtca gagagtagag atattgcgcc ttggtcatct
    17221 cgctccaatg tgggcggtct ttggcaatat tgtccgtaat tactttagtt ggatgatagt
    17281 attcttccac agccttgtca tggtcgtctg caatccaacc ccaagaatgg gctgcaactt
    17341 tcgttttctt tggatcatga cctgagttgc gagcaacctt gcgataagca tcgactaaag
    17401 gtttaaagcg atgggcacct gcaccaatga ctgcatacac gattggcagg cctttcttag
    17461 caatcttgat ggtggactct acattgcccc cagttgcaac ccagatcgga aaatcttcct
    17521 gaacaggacg tggatagact ggcttattat cgactgactg ggtaaaatgc ccatcccact
    17581 tgagattggt ttccttgccg atttccagaa gcatatctag cttttcatcg aagagttctt
    17641 catagtcgtg gagatcatag ccaaacaagg ggaatgactc cgtaaaggaa ccacgacccg
    17701 ccatgatttc cgctctgcca tttgacaaag catcaatggt ggtgtactgc tgatagagcc
    17761 ttacaggatc catggaggaa aggattgaaa ctgctgatgt tagcttgata tgcttggtat
    17821 tgacggcacc agctgccagc acaatctcag gtgcagaaac cgcaaaatct tctcggtgat
    17881 gctccccaat cccataaaca tcaagtccca ccgcatcagc tagttcgatt tctttgacta
    17941 gctggcgaat ccgctcgtcg tggctgtaag tttcccctgt tttttctagt ggagttgttt
    18001 cgccaaatgt tgaaatacct aattctacca tgatgtgttc tcctttgaaa tcactatttc
    18061 ttaattgatg cgtttatttt atcgctaatt agtgataaat tcaattaatt tgctcaaaaa
    18121 ataaaacgac taggaaaacc taatcgtttc aatagattat tcatagcgca aagcttcaat
    18181 tggatcaagc ttagatgctt tgttggcagg tagtacgcca aatacaatac caactactgc
    18241 tgagaaagcc agactaccta acacaacagg aattgaaatt tcagcagcta ttctttcgcc
    18301 caacgccttg ctcacattga gcaagaaaac tattgtctga gcgattgcga gaccaattgc
    18361 tccaccaaga gtggtcaaga ccatggcttc tatcaagaat tgaatcaaga tatttcctct
    18421 agttgctcca agcgcttttc gaagaccgat ttcacgagtc cgctcagtta ctgataccag
    18481 catgatattc atgacaccga taccaccaac tagcaaggag atacctgcaa cagcaccgat
    18541 aaacaatgta acgccagaca tttgagattt aaactcctcc aacatagctg acatatcata
    18601 aatctcgtat ctcgcttctt tcaatccagt cgctttagtc aggtaatctg cagcagcctt
    18661 cccaacttct gttgcccgag taacatcttc aacatggaca aagatttgag aattttcttt
    18721 catgcctgtt tcagcagcta gctgcgtatt agtcatgacg gcatttccac ctgaattcat
    18781 tccataaata gctgtgcctg ctttcggatc tttgtagacc cctattacta gataggcatt
    18841 gctattaaca ctaatcgtct gattgagaga gttctctata gaaccaaata acttctctgc
    18901 taatgccgta tctaacataa tcatacgtga aaaacgacta tagtcgttag ctgtaaactg
    18961 acgaccagct aaaatctcat actctttcac agcaaagaaa ttctggctaa caccagtaat
    19021 agtgacattc tctgcttttt tattgcccga tctgacttca gctatgttgc tgatgctgga
    19081 gtaatagttt gatacgccat caatctctag cagtcctttt aaagtagaat ccgtcaaatc
    19141 cggctcttcc tctaaaattg gttcttctgt cgacgctgtg ccaaacggac cgaaagctgt
    19201 acctgaactg gagaaagcag taaagtaaac ctgaacatta ttttgatcac cagctagaga
    19261 cttttctatg cttttggcca cccctgttcc catggcgaca ataatgacaa ctgcagccac
    19321 accaatgatg atacctaaca tagtaaggag cgatctcatt ttatgagcca taatagattt
    19381 gagggcgaat ttccaatttt ccatctaaac tccctccctt cgactatctt cagtgatcac
    19441 tccatcacgt agaacgattt ttcgttttgc gtaggcagca atctcaggct catgcgtaac
    19501 catgataatg gtctttcctt cattattcaa ctccgtcaga agttgcataa tctgctcacc
    19561 tgtcttggta tctagagccc ctgtaggttc atccgctaaa ataatagctg gggtattgac
    19621 tagtgcacga gcaatagcta cccgttgttt ttgaccacca gacaattctg atggtaaatg
    19681 cgtcatccgc tctgccaact caactttttc aagatactgt tttgctagtt ccttacgttt
    19741 gcttgatgga actccagcat aaatcaaggg taattctaca ttttgaaggg cgttaagttt
    19801 cgataagagg aaaaattgtt gaaagacgaa accgatttgg tcattccgaa cctgagctaa
    19861 ttttttctca gaaagttgac tgacttcttc accttccagc caatagtttc ctgaactgaa
    19921 acgatccaaa agcccaataa tgttcatcaa ggttgatttc cctgaaccag agggccccat
    19981 aatggcaaga aattctccct cttccacctc taaatcaata ttctttaaaa ctcggagttc
    20041 ttgatcacca tttttgtagg atttattgat acttgttagt ctaataagct ggttcttcat
    20101 tggcttcaac ctctttgcca tcttcgagat tcggagttgg aatggtaata accttatctc
    20161 ctgctgctat accagcggtc acttcctggt tcaaagcatc tgcgttcccc agagtaactt
    20221 ctactttctt agctttccca tcaaccaagg tccacacata gtttttatct tcttctggca
    20281 caactgcgga caccggaatt aaaatgtttt tacttgtatt gacaacctca atatttacag
    20341 aaaatccttg tttcaactca cctaattcac tagttaaagc tgccttaaat ggatatttgg
    20401 cacctgaacc actggttcct gttgtagcag caccagcttg attactagat ggatagtttg
    20461 aaatataggt aattttcccc gtccaagtct tatcgggata taccttgcta gtcagcttga
    20521 cctcttgatc cactgcaatg ttagccaaat cgtattctgt caaactacct gttacttgca
    20581 aactaccttg atttacaatg tgtacaactg tttggctcga tgtagaattc ttagaaacag
    20641 ccttattcac ctcaacaact gtaccagcaa cggtactagt tactgtcgct tctgttaagg
    20701 ctgtatatgc tttatcaacc gcagcttgag catctgcgta tgaatcattc aagtctgcca
    20761 actgcatatc tactgaacgt tgtgcagtag cagttgctgc agcatctgtt tctgcatcac
    20821 cagttgtttg aacagtctga ccgttggttc ttaagtctgc aatttggcga ccaatcttat
    20881 cacgaccacg aacagcagta tccaaagcag actgtaattc tgtagcatca tagcgaatca
    20941 aaggggtacc tacttcgacc ttagcacctg gagcaaccaa aacctcactc aaatctccct
    21001 tagaaggatc atagtaaaca tactgctcgt ctgctgctgt aatcgttcct gtaagtagcg
    21061 ttgaggaagc aattgagcct tctttagcaa cagtataggt catactcatg gctacatctt
    21121 ctgaagatga tggtgatgtt agcatattgc taaaaatcaa agccccacct actaaggcaa
    21181 ctgcgaccac tccaagacca ccaaacaaag caatttttgc tttctttgtt tttaacataa
    21241 caaactcctt ttctttacaa aacataccta tttgtgttgt ctatataata cacaaataca
    21301 agaacaaatg caagtttttt cctaactatt ttataaaaag ttcggcaatt ttcccactta
    21361 catttttgta aggtgacgta gcagattttt gattgacata caaaaaagcg ttacaatgaa
    21421 tataattatt gacctttatt ggaggaaatt tatgaaagtg tttgatatta tcgctatcgg
    21481 tggtgggagc ggaggcatcg ctaccatgaa ccgagctgct atgtacggtg ccaaggcagc
    21541 agttattgag ggaagctatc taggagggac ttgtgttaac cttggctgtg tacccaaaaa
    21601 aattatgtgg tacggctctc aggtagcaga agccattcag cattatggac ctgaatatgg
    21661 atttactagc caagaagtga cctttgattt tgccaccttg cgtaaaaatc gcgaagccta
    21721 tattgagcgt tcacgcgcat cctacggtaa tacttttaac aataacgaag tagaagttat
    21781 ccagggtttc gcacgttttg tggataatca aacggttgaa gtcaatggtg aactgattcg
    21841 tgcaaaacac attgtcatca caactggcgc caaaccggta gtccctgcta ttcctggtag
    21901 tgagctaggg attgtatctg acgatgtctt tgcatgggaa gaattaccct cttctgtggc
    21961 tgtgattggt gctggttata tcgctgtgga aatggccggt ctcctacatg gactcggtgt
    22021 ccaaactgac ctatttgttc gtggtaatcg ccctcttcgt agctttgata cctacattgt
    22081 tgatgccttg atggaagaaa tgcaacgtac caaccttcca ctccataccg ggaaaactcc
    22141 tgtcagtctt gaaaaaactg atgatggaca aatccagatt aactttgctg acggtagtaa
    22201 ccatattgct cagaaggtcc tttgggcaat tggacgtaaa ccaaatattg acaaactcaa
    22261 cctgaaagca actagtgttc aacttacttc ttcaggacat atttctgtca atgaatacca
    22321 agaaacagct gtaccaggca tctatgccct cggtgatgta actggtgaaa aagaattaac
    22381 acccgttgca atcaaggcag gtcgcctttt ggcagaacgt ttatttaaca ataaaccaac
    22441 cgcaaaaatg gattacacaa ccatcccaac tgtcgtcttt tctcaccccg ctatcggaac
    22501 cgttggtcta actgaggacg aagcgattac ccaatacggt caggacaatg taaaagtcta
    22561 tacttcagcc tttacttcta tgtacactgc cctagaaaac aatcgccaaa tggctaagtt
    22621 taaattagta actgtgggag aaaatgaaaa agtcgttgga ctgcacggca ttggctatgg
    22681 tgtcgatgaa atgattcaag gattctcagt tgctatcaaa atgggagcta caaaagaaga
    22741 atttgatgcc gttgtcgcca tccatccgac aggttctgaa gaatttgtta ctatgcgtta
    22801 actcaattga aaaagtccag acatgaaggt cagcactgtc tggacttttt ttatggtaat
    22861 atggcaattg ctcgcactgg tgaacccgaa gccttctccc aatgaggaaa agcgattgaa
    22921 atcaatgcac ctgttggcgg tacctgatcc aagtttgcca atacttccaa ctgataaata
    22981 tcttttgata ggagatagta ttcttctgat aaacttcctc cgtgtttggc tgcagatact
    23041 cctgaatcgg tatccaatgt ttcatgacca actgctttca cctgacgttc ttcaatcaaa
    23101 tattctagag cttcatgact ccatcctggt gtacgttgaa ctccatcttc gtctagatta
    23161 cgaatggcat cttgactagg ccagcgcttt gacaaatccg aacgaaaggc aacaaaagat
    23221 tttggcgcta tcggaccata ttcagcctca aagtctaaaa tatcctgctt agttatctca
    23281 tagtcattat tttctataac agcagctgat ttatcaataa cgtagagtgg caggagtaaa
    23341 tctttcaaat caatctcatc aagataacga gccccttcta caaaatgaat cggaggatca
    23401 atatgggttc cgtactgccc cacaaccgta aattgttcga caaagaagcc atccttatga
    23461 gtaaataggg ctttcttttc gagagctggt agcgcaggga aatgcgggct cttttcattg
    23521 atttggtgag tcaagtctac ccaagtttta gatttaagag tacggtaaat atcaagtaat
    23581 tctgtcatag aaattctcac tttctttttt tat
//
LOCUS       DBNFCO010000027        22585 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.027, whole genome shotgun sequence.
ACCESSION   DBNFCO010000027 DBNFCO010000000
VERSION     DBNFCO010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 22585)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22585)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22585
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.027"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            1..778
                     /locus_tag="AC1PIV_000904"
                     /pseudo
     CDS             1..778
                     /locus_tag="AC1PIV_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935295.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(987..1889)
                     /locus_tag="AC1PIV_000905"
     CDS             complement(987..1889)
                     /locus_tag="AC1PIV_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIP6611939.1"
                     /translation="MSKENKKQVQSASTPPGGFRVIAREFMKDRLALTSLIILVTVLL
                     AVFIGALLLNQEQVMKVNLLGRYLEPGVDGYILGTDEGGKDIFGQLIIGARNSIIIGF
                     TITIITSIVGISVGLISGYYGGRLDGFLMRIVDFIMILPVTMLIIVFVTVIKNYTIYH
                     FILIMSAFYWTAKARLFRTRTLSEASLDYVNASKTLGTSDFMIMFREILPNLSSLIIV
                     NLTLNFAGNIGIEASLTYLGFGLPSTVPSLGTLIANARNADILENKTWIWLPAAIFIL
                     VMMLCINYVGQAFQRAADAKQRLG"
     gene            complement(1903..2859)
                     /gene="opp4B"
                     /locus_tag="AC1PIV_000906"
     CDS             complement(1903..2859)
                     /gene="opp4B"
                     /locus_tag="AC1PIV_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease"
                     /protein_id="HIP6611940.1"
                     /translation="MWKTVLRRLLMMIPQIIILSVIAFFVAKMMPGDPFTGLIDPNID
                     PAIIEQKRIAAGYYDPIPVQYFRWVGNLLQGDFGQSVIFKQPVVDVIMQRLNNTIGLS
                     LLTMVLTYLIALPLGMIAGRYQNSLADKIIGVYNFLTFSTPTFVFAILMLWMFGFSLG
                     WFPTRGSISGGVEGFAATLSRLHHMILPAITMAILSTTVTIQYLRTGIIDAKSQDYVR
                     TARAKGVPERVVYNRHIFRNSILPIASFLGYELTGLIGGSIFIENIFTYPGIGQLFFN
                     SISSRDYSVILALLLVFGMGTLLGTLISDIIMSIVDPRIRVK"
     gene            complement(2861..3802)
                     /locus_tag="AC1PIV_000907"
     CDS             complement(2861..3802)
                     /locus_tag="AC1PIV_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HIP6611941.1"
                     /translation="MGFIEVKDLKVHYPIRSGFFNRVTDHVYAVDGVNIEFEEGKTYG
                     LVGESGSGKSTIGKAIIGLERATSGQIIYEGQDVTNKSRGKKGNFNRDVQMIFQDSLS
                     SFNPKKRILDIIAEPIRNFDRLSPDEEKKKVLQLLDTIGLNEEALIKYPHEFSGGQRQ
                     RIGVARALASNPRLIIADEPVSALDLSVQAQVLNYMKRIQDEFKLSYLFISHDLGVVQ
                     HMCDELFIMYRGRFVETGNKNDIYNNPQHIYTKRLLSAIPTIDPLNRLKNKEKRLAAE
                     KEYQEMQGQYYDENGRVYDLRSFSETHQVALPEGGQN"
     gene            complement(3805..4803)
                     /locus_tag="AC1PIV_000908"
     CDS             complement(3805..4803)
                     /locus_tag="AC1PIV_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIP6611942.1"
                     /translation="MATEKPLLDIKDLHVGFRIGDDYFDAVDGVDISLQKNEILAIVG
                     ESGCGKSTLATTIMGLHNPLNTKITGSIQYNDMELIGMDEAKYNTVRGNDIGMIFQDP
                     LASLNPLMTIGAQIDEALFYHTDLDANARTERVLELLAQVGIPNPKRTFKQYPHELSG
                     GMRQRIIIAMALSCKPPIIIADEPTTALDVTIQAQILDLLNDIQAETGSGIILITHDL
                     GVVAETADRVAVMYGGQFVEVAPVEELFTNPKHPYTRSLLKSNPQSGSEGGDLHVIEG
                     IVPPITKMVRKGCRFAPRIPWIGAEAHEENPSMHEVGPNHFVRCTCHETFYFEGEA"
     gene            complement(5180..6970)
                     /locus_tag="AC1PIV_000909"
     CDS             complement(5180..6970)
                     /locus_tag="AC1PIV_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014917310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HIP6611943.1"
                     /translation="MKKTTKLFALAGVTLLSASVLAACGSKQSGAAKQELSFPAEVKQ
                     DGTAVADAQLKYAWVSPTTSSGLLIDELTENTTDSTFGGMVDISMFGYDGERKLDDSG
                     LAKAEFDVKGKKITVSLTGKDYKWSDGESFTINDYIFTIKSMASKDYTGIRFDDKFLN
                     IEGMQEFVDGKASDISGIKKVDDYTVELTVKEMSPSMMYAGGDVPAYIQPEHIYKDIP
                     VADWEKSEYSRTAKLVGMGPWKIKEIVNGESITYVPNEYFFKGTKPKTSSLKIDIVSP
                     DTIVSEMKAGNYDIAEMPVDQLDSYKDASNLNIVGQLESSYEYISFNFGKYDEAAGKN
                     VMDENAKMNDVKLRQAIAYAIDTKTAGKSLYNGLYHPAKSLIISFFGDIHDSELEGYS
                     YNPEKAKKLLDEAGYKDVDGDGIREGKDGKAFKITFAARKRTEANEALVQQYIAWWKE
                     VGLNVELYTGRTVEGKSFYNSVQANDAAIDMYAGGWSTGYDPNPSGLWGPIAAFNMSR
                     FVSDENTKLLEAISSAESFDDKKNVENYKAWQKYAHEQAFAIPTFESEKITAVNKRVK
                     SYDTKYGSASGTGLAYEGIELTADKGVVAE"
     gene            7183..8424
                     /gene="pbp3"
                     /locus_tag="AC1PIV_000910"
     CDS             7183..8424
                     /gene="pbp3"
                     /locus_tag="AC1PIV_000910"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase PBP3"
                     /protein_id="HIP6611944.1"
                     /translation="MRKLLLTLTTILAVFLTSTPILAEDFSVAAKHAIAVEVSSGKIL
                     YEQDAETKASIASISKTLSIYLVYEALAKGEITLDTMVDISDYPYSLTSNTELSNVNL
                     DERSYSVRDLLNASLITSSNSAIIALAEKIAGSEAAFVDRMKAKVQEWGITDTKIVNV
                     SGLDNTDLGENIYPGSSPEDVNMFSALDVAIIARRLILDYPQVLDITSLNAYDFGGYT
                     YYSTNQMLSDGTHARGGVDGLKTGTSNSAGSSFLATTQQAGMRIITVVLNANDGLTSP
                     ENRFVATNDLMNYVYSNFSLVTLVKKSEAFGDSKIKVFNGEKETSPVVAAADLTVVQR
                     NQTDNVPTATFTTDIKEIDAPLKAGTLVSKLQLKDQDLIGKGYISEQTGVDMIIPSDM
                     KEASWPFSWWNQFVRYVNEKL"
     gene            complement(8677..10092)
                     /gene="sufB"
                     /locus_tag="AC1PIV_000911"
     CDS             complement(8677..10092)
                     /gene="sufB"
                     /locus_tag="AC1PIV_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HIP6611945.1"
                     /translation="MSEERIEPTPIDLGEYKFGFHDENVELVASTGKGLNEEVIREMS
                     RIKGEPEWMLEFRLKSYETFKKMPMQTWGADLSELDFDDIVYYQKPSDKPARSWDDVP
                     DKIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEYDKHGIIFTDTDTALKEHP
                     ELFKKYFGKLVPPSDNKLAALNSAVWSGGTFIYVPKGVKLDIPLQTYFRINNEGTGQF
                     ERTLIIVDEGASVHYVEGCTAPTYSTASLHAAIVEIIAHEGAYMRYTTIQNWSDNVYN
                     LVTKRARAEKNATVEWIDGNLGAKTTMKYPAVYLEGEGARGTMLSIAFANKGQVQDTG
                     AKMIHNAPRTSSSIVSKSIARGGGEVNYRGQVTFAKNSAKSISHIECDTIIMDDISKS
                     DTIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKEL
                     PMEYAVELNRLIAYEMEGSVG"
     gene            complement(10442..10882)
                     /gene="sufU"
                     /locus_tag="AC1PIV_000912"
     CDS             complement(10442..10882)
                     /gene="sufU"
                     /locus_tag="AC1PIV_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly sulfur transfer protein
                     SufU"
                     /protein_id="HIP6611946.1"
                     /translation="MALSRLDSLYMAVVSEHSKSPRHRGSLDGVEKLELHNPTCGDVI
                     ELSVKIEKDVITDIAFDGVGCTISTASASMMTEAVLGKEISQIQELAEIFSQMVRGQE
                     DPRQKELGDASLLAGVAKFPQRIKCATLPWNALKKALSLRSSAE"
     gene            complement(10869..12092)
                     /locus_tag="AC1PIV_000913"
     CDS             complement(10869..12092)
                     /locus_tag="AC1PIV_000913"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006534 - cysteine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HIP6611947.1"
                     /translation="MDLERIRKEFSILDQVVNDEPLVYLDNAATTQKPQQVLDVLADY
                     YQKDNANVHRGVHTLSERATTRYEAARQKVADFIQAKSSKEILFTRGTTTSLNWVAQF
                     AKEILQPDQEVIISVQEHHSNIIPWQQACQQTGAKLRYVTLKDGELDMDHLRSLLSSK
                     TKFVSLAHVSNVLGGVVPIGEIAELVHQVGAYLVVDGAQSVPHMGVNVQELDVDFYAF
                     SGHKMLGPTGIGILYGKEELLNLMSPVEFGGEMIDFVYEQSATWKELPWKFEAGTPNI
                     AGAIGLGAAIDYLTEIGMDAIQAHEAELVDYVFPKLQAIPGLTIYGSQDLSKRTGVIA
                     FNLDDLHPHDVATALDYEGVAVRAGHHCAQPLLRYLQVPATVRASFYIYNTKADCDKL
                     VEAIIKTKEFFNGPI"
     gene            complement(12096..13358)
                     /gene="sufD"
                     /locus_tag="AC1PIV_000914"
     CDS             complement(12096..13358)
                     /gene="sufD"
                     /locus_tag="AC1PIV_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HIP6611948.1"
                     /translation="MTKEKIQEFSALQAEPTWLTDLRLKAFDKIAELDLPVIERVKFH
                     RWNLGDGSLATNDEIGAVPDFTAIGDNPMLVQVGSQTILEQLPVALVEKGVVFTDFAS
                     AMDVIPDVLEKYLGAAVAYDEHKLAAYNTAYFNATAVLYVPDNVEIDQPVEALFYQDS
                     TSPVAFNKRVLIIAGKNAKLNYLERFESLGDGAATTSANIVVEVIALAGSQIKFAAID
                     RLGKHLDTYLNRRGYLGNDATIDWAIGLLNEGNVVADLDSELKGNGSHANLKVVGLSS
                     GRQVQGVDTRVTNYGHNSVGHILQHGVILESGTLTFNGIGHIVRGAKGADAQQESRVL
                     MLSDKARSDANPILLIDENEVTAGHAASIGQVDPEDMYYLMSRGLDRATAERLVVRGF
                     LGSVITEIPVKEVRDQLIAVIEEKLTKR"
     gene            complement(13375..14148)
                     /gene="sufC"
                     /locus_tag="AC1PIV_000915"
     CDS             complement(13375..14148)
                     /gene="sufC"
                     /locus_tag="AC1PIV_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HIP6611949.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPSYEVTQGEILFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDEDKISVRDFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGINAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAQRLEKEGYVQVAAELGIDYKEDDI"
     gene            complement(14701..15873)
                     /locus_tag="AC1PIV_000916"
     CDS             complement(14701..15873)
                     /locus_tag="AC1PIV_000916"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0070085 - glycosylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HIP6611950.1"
                     /translation="MIPFALKYIMVIITTMVISAIATPLVRFMSLRVGAVDNPNARRI
                     NKVPMPSAGGLAIFVAFTISVLWFLPGIVTRVNYHGTYLHYIWPLVLASSIIVLTGFI
                     DDVKELKPAPKMFGILAAATIIWIFTEFRFDSFKIPFGGPFLQFPVWLSFLLTVLWIV
                     SITNAVNLIDGLDGLVSGVSIISLTTMGIVSYFFLHDSNIFLTLTIFVLVAAIVGFLP
                     YNYNPAIIYLGDTGALFIGFMIGVLSLQGLKNSTAVAVVTPMIILGVPITDTVVAIIR
                     RKLSGQKIYEADKMHLHHRLLSLGLTHRGTVLVIYAISFLFSLTSLLLNVSSRIGGIL
                     LLVTMGLGIEILCELIGIFGINRTPLLNLLRFIGNSSYRQEKIAKYKKCCEEKKRK"
     gene            complement(15870..16592)
                     /gene="mecA"
                     /locus_tag="AC1PIV_000917"
     CDS             complement(15870..16592)
                     /gene="mecA"
                     /locus_tag="AC1PIV_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HIP6611951.1"
                     /translation="MKVKQISDSTLKITIKLDDLEERGMELSDFLIPQEKTEEFFYTV
                     LDELDLPMTFRESGMLSFRVTPKPDRVDIFVTKSDLDQNLNFDEFTDLSELGDVASMT
                     PDEFFKSLEQTVREKSAPDATAVRHLEEVEQEEEADEEEQERYIYYILEFPTIEDLFT
                     FVGTVDYPVEESELYKMDGHYYLTVLINVENRSKQYPGYILSRMLEFTNDTKLTRPAL
                     QEHGTLMLPLAAIEELRKVPTV"
     gene            complement(16720..17556)
                     /locus_tag="AC1PIV_000918"
     CDS             complement(16720..17556)
                     /locus_tag="AC1PIV_000918"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HIP6611952.1"
                     /translation="MLLELLKAIFLGIIEGVTEWLPVSSTGHLILVQEFVKLNQSKNF
                     LEMFNIVIQLGAILAVMTIYFKKLNPFQPGKTKRDIQLTWQLWAKVVIACIPSILIAV
                     PLDNWFEAHFNFMVPIAIALIVYGIAFIWIENRNRGIEPQVTDLAKMSYKTALLIGCF
                     QVLSIVPGTSRSGATILGAIILGTSRSVAADFTFFLGIPTMFGYSGLKAVKYFLDGNS
                     LNMEQVWILLVASVTAYLVSLVVIRFLTDFVKKHDFTVFGYYRIILGAILLVYAFITF
                     LF"
     gene            17683..19248
                     /locus_tag="AC1PIV_000919"
     CDS             17683..19248
                     /locus_tag="AC1PIV_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HIP6611953.1"
                     /translation="MKRKLSIFLLTLIAVFSVTTGVRADEYLRVGMEAAYAPFNWTQE
                     DDSNSAVPIEGTNQFANGYDVQVAKKIAASMDKELLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTEERKKEIAFSDSYYTSIPTLVVRSDSQYANATSLEDFAGAKITAQQGVYLYD
                     LIDQIEGANKQTAMGDFSQIRQALESGIIDAYVSERPEGRTAEAANKAFKMVELADSF
                     ETNAEDVTIAVGMRKDDERIAQVNEVLATISEEEQIALMDDMIENQPVEEASEGETPS
                     FFAQVWNIVVNNWQQLLRGTGMTLLISILGTIIGTAIGLLIGVFRTAPKAANKALAIG
                     QKVLGWIINIYIEIFRGTPMIVQSMVIYYGTAQAFGLNLDRTLAAIFIVSINTGAYMS
                     EIVRGGIFAVDKGQFEAATALGFTHNQTMRKIVLPQVIRNILPATGNEFVINIKDTSV
                     LNVISVVELYFSGNTVATQTYQYFQTFTVIAIIYFILTFTVTRILRAVEKYFDTDTYT
                     TGANQMQVEVPHD"
     gene            19241..19984
                     /locus_tag="AC1PIV_000920"
     CDS             19241..19984
                     /locus_tag="AC1PIV_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015424 - ABC-type amino acid transporter
                     activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HIP6611954.1"
                     /translation="MTKNVILEIKNLKKSYGQNQVLKDISISVEKGEVISIIGSSGSG
                     KSTFLRSINLLETPTEGQILYHGQDVLAKGYDLTTYREKLGMVFQSFNLFNNLNVLEN
                     AIVAQTTVLKRDRAEAEKIAKENLNKVGMTEQYWQAKPSQLSGGQKQRVAIARALSVD
                     PEVILFDEPTSALDPEMVGEVLKTMQDLAKSGLTMLIVTHEMEFARDVSDRVIFMDKG
                     VIAEEGSPQQIFENPQEERTREFLQRFLG"
     gene            complement(20110..20319)
                     /locus_tag="AC1PIV_000921"
     CDS             complement(20110..20319)
                     /locus_tag="AC1PIV_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009910800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611955.1"
                     /translation="MTSYEKVAAVVGWVREKKITGYRISKETNAREMSVIALAQGRAK
                     IDNISFATALGLIDFYDKNHKKFEN"
     gene            complement(20405..21307)
                     /locus_tag="AC1PIV_000922"
     CDS             complement(20405..21307)
                     /locus_tag="AC1PIV_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HIP6611956.1"
                     /translation="MVFGPIVFIGSFLFFVLIALILIASGLYVVKQQTVAIIERFGKY
                     QKTSTSGINFKIPFGVDVIAARIQLRMLQSEIVVETKTQDNVFVTMNVATQYRVNENN
                     VTDAYYKLMHPEAQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQKQVAEEMSTYG
                     YVIVKTLITKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRL
                     HGVGIAQQRKAIVDGLADSIRELKESNVSLSEEQIMSILLTNQYLDTLNNFAQGGNQT
                     IFLPGNPEGVEDIRTQILSSLRAK"
     gene            complement(21317..22567)
                     /gene="ilvA"
                     /locus_tag="AC1PIV_000923"
     CDS             complement(21317..22567)
                     /gene="ilvA"
                     /locus_tag="AC1PIV_000923"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019322143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004794 - threonine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HIP6611957.1"
                     /translation="MITAKNVEQAYSVLKRVVVRTPLDYSRYLSEKYGATIYLKRENE
                     QRVRSFKIRGAYYAISQLTDDEKSRGVVCASAGNHAQGVAYTCQEMQIPATIFMPITT
                     PQQKIGQVKFFGGDYVEIRLVGDTFDESAKAAQDYTQESGKTFIDPFDDENVQAGQGT
                     VAYEILEEAEEQTISFDQILVPIGGGGLVAGVSAYLKEHAPEIKIVGVEASGARSMKA
                     AFDKGRPVKLDQIDKFADGIAVQKVGKSTYEVARKYVDRLIGVDEGWISGTILDLYSK
                     LGIVAEPAGAATIAALEVVKDQIKGQTICCIISGGNNDINRMPEMEERALIYEGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRANKGTGPVLIGIALGDKTDYTQFI
                     SRLEEFDPQYINLHENDSLYKMLV"
BASE COUNT         6648 a         5138 c         4327 g         6472 t
ORIGIN      
        1 attgttcgag ctaaaaaccg cctgcacaag gtcttacagg tcactttccc tgaattggaa
       61 aatatcttgt caacaccatc tggcgaacaa tactggaact tagttatagc ttttccttgc
      121 aaggacttcg tgcttgagtt aagcaatgat gaactctcaa agagcatccg tctgtccact
      181 tcaaaacgga tttctgataa gcgtgtggct tacttagcag aaaagcttat agcactagct
      241 aatcaatctt attgtgccgt caagaaaacc tctccaatac tggaagaggt ccgttactat
      301 gcaaagactt tatgaacaga gacaagctgt cttagacgaa atggtggaac tagctcagcc
      361 attacctgaa tatgacattc tgctctctat tcctggaata gctgagacta ctgcaacaag
      421 tattattggt gaactgggag atattcgccg ttttcagtca gccaaccaaa tcaatgcctt
      481 tatcggtatt gacctgagac actatgaatc tggtaacttc ctcgctaagg aacacattac
      541 caagcgtggc aatccctacg ctagaaagat tctgttcaaa tgcattcaca atatcgcttc
      601 agccagtcat accaatcctt gccatatcgc agacttttat gagaaacgaa aaagacaatc
      661 gcaaacgact tcaacgaagt cgcacacgat tgcctccata catcgtctca ttcggacaat
      721 gtattacctc attatgcata acaaacttta cgattacgct tcaactcaaa atcggtaaaa
      781 ctgtttatgc catatcattg taacacctta tcaaaaaatt tcaacataag gtgttggttt
      841 tgtatgcact ttttacacta aaatttagtc caaaataaaa caatttcctt attttgacta
      901 ttgaactcaa aatatttttc gtcaaatacc ttgatggact tgacaaatag tagaaaaaag
      961 agttcccaaa ggaacccttt tcacaattaa cctaaacgct gcttagcatc tgctgcacgt
     1021 tggaaagctt gtccgacata gttgatacag agcatcatca caaggatgaa gatggctgct
     1081 ggcaaccaaa tccatgtctt gttttccaaa atatctgcat tgcgagcatt ggcaatcaag
     1141 gtacccaaac ttggtactgt cgatggcaga ccgaaaccaa gataagtcaa cgaagcctcg
     1201 ataccgatat ttcccgcaaa gttcaaggtc aagttaacga taatcaatga acttaagttt
     1261 ggtaaaattt cacggaacat aatcataaag tcgcttgttc ccaatgtttt tgatgcattt
     1321 acatagtcca aacttgcctc tgacaaagtc cttgtacgga atagacgagc cttggccgtc
     1381 caataaaagg cactcatgat gagaatgaaa tgatagattg tatagttctt gataactgtc
     1441 acgaaaacaa taatcaacat tgtcaccggc aaaatcatga tgaaatcgac aatacgcatc
     1501 aagaatccat ctaaacgacc gccataataa ccagaaatca gaccgacaga aatcccgaca
     1561 atacttgtaa taatcgtaat ggtaaaaccg ataatgattg agttacgagc gccgataatc
     1621 agctgaccaa agatatcttt accaccttca tctgtcccca agatatagcc gtcaacacct
     1681 ggttccaagt aacgtcccaa aaggttgact ttcataactt gttcttgatt caacagaagt
     1741 gcaccgataa agactgctaa gagaaccgtc actaagataa ttaatgaggt caatgcaagt
     1801 cgatctttca taaactcccg cgcgatgaca cggaagccac ctggaggagt tgaagcagat
     1861 tgtacttgtt ttttattttc tttactcacc ttactcctcc ttctatttca cacggatacg
     1921 tggatccacg atactcatga taatatctga aatcaatgtc cccaacaaag tacccatacc
     1981 aaataccaac aataaagcta agataacact atagtcacga ctagaaatag agttaaagaa
     2041 taactgaccg atacctgggt aagtgaaaat attttcaata aagatagaac caccaattaa
     2101 tcctgtcaat tcatagccca agaaagatgc gattggtaaa atcgaattac ggaaaatatg
     2161 acggttataa acaactctct caggaacacc tttggcacga gctgtacgaa catagtcctg
     2221 actcttagca tcaataatcc ccgtacggag atattgaata gtaactgttg ttgacaaaat
     2281 agccattgta atcgctggca gaatcatatg gtgtaaacga ctgagagtcg ctgcaaatcc
     2341 ttccacacct ccactaatcg aaccacgcgt cgggaaccag cccaaactaa agccaaacat
     2401 ccagagcatg agaatggcaa aaacgaaagt tggagttgaa aatgtcaaga agttatacac
     2461 gccaatgatt ttatctgcaa gtgagttttg ataacgacct gcaatcatac ccaatggaag
     2521 tgcaatcaaa taagtcaata ccatcgtcaa gagggataat ccaattgtat tattcaagcg
     2581 ctgcatgatg acatcaacaa ctggttgttt aaaaataaca ctctgaccaa aatctccttg
     2641 caaaagattg cctacccagc ggaaatactg aacagggatt gggtcatagt aacctgccgc
     2701 aatccgtttt tgttcaatga ttgctggatc aatattgggg tcaatcaatc ctgtaaaggg
     2761 atcccccggc atcatcttcg caacaaagaa cgcaatgaca ctcaaaataa taatctgcgg
     2821 aatcatcatg agtaaacgac gtaatactgt tttccacatc ttagttctga cctccttctg
     2881 gaagggctac ttgatgagtt tctgagaagg atctcaaatc gtacacacga ccgttttcat
     2941 catagtattg accttgcatt tcttgatatt ctttttcagc agccaaacgc ttttctttat
     3001 tcttcaatcg attgagtggg tcaatcgttg gaatagctga caacaaacgt ttagtataaa
     3061 tgtgttgtgg attattataa atatcgttct tatttcctgt ttctacgaaa cgtccgcgat
     3121 acatgatgaa caattcatca cacatgtgtt gcacaacacc gaggtcatgg gaaataaaga
     3181 gatagctgag cttaaactca tcttggatac gtttcatata attcaagacc tgtgcctgca
     3241 cagacaaatc caaggcagaa accggctcat ctgcaataat caaacgagga ttactagcca
     3301 aagcacgagc aacaccgata cgttggcgtt gaccacctga gaattcgtga ggatacttaa
     3361 tcagagcttc ttcatttaga ccgattgtat ccaagagttg aagaactttt ttcttttctt
     3421 catctggaga taaacggtca aagttacgaa ttggttctgc aatgatgtcc aagatacgtt
     3481 ttttcgggtt gaaacttgaa agagaatctt ggaaaatcat ttgaacatca cgattaaagt
     3541 ttcctttttt accacgtgat ttgttggtta catcttgtcc ttcatagata atctgaccag
     3601 aagtggcacg ctctaaaccg ataattgcct taccaatggt tgatttccca gaacctgact
     3661 cacctaccaa accataggtt tttccttctt caaactcaat attaacacca tccacagcat
     3721 agacatggtc cgtcacacgg ttaaagaagc cactacgaat tggataatgg acttttaaat
     3781 cttttacttc aataaatccc actattaggc ctccccttca aaatagaatg tctcatggca
     3841 ggtacaacga acaaagtgat ttggacctac ctcgtgcatg ctcggattct cttcatgagc
     3901 ctctgctcca atccacggaa tacgcggagc aaaacggcaa cctttacgaa ccatttttgt
     3961 aatcggcggc acaatacctt caataacatg aagatcgcct ccttcgctac ctgattgagg
     4021 atttgacttc aagagcgaac gtgtatatgg atgtttagga ttggtaaaca attcttctac
     4081 tggcgctact tcgacaaact gaccaccgta catgaccgcc acacgatcag cagtttctgc
     4141 aactactccc aagtcatggg taatcaaaat aataccagaa cctgtctccg cttgaatatc
     4201 atttaagaga tccaagattt gtgcttgaat tgtaacatcc aaggctgttg taggttcgtc
     4261 cgcaataata attggcggtt tacaagacaa ggccatcgca ataatgatac gctgacgcat
     4321 accacctgaa agctcatgtg gatactgttt aaatgtccgc ttaggatttg gaatacctac
     4381 ctgagccaag agttccaaaa ctcgctctgt acgagcattg gcatccaaat cagtatgata
     4441 gaacagtgcc tcatcaatct gtgcaccaat cgtcatcaat ggatttagag aagctaaggg
     4501 atcttggaaa atcataccaa tatcattacc acgtactgta ttgtacttag cttcatccat
     4561 gccaatcaat tccatatcat tgtactggat gcttcctgtg attttggtat tcaaagggtt
     4621 atgcaagccc atgatggtcg ttgccaaagt tgattttcca cagccagatt cccctacaat
     4681 tgccaaaatt tcattttttt gcaatgagat gtcaacaccg tcaacagcgt caaaataatc
     4741 atctccaata cggaaaccga cgtgtaaatc tttaatgtct aaaagcggtt tttcggtagc
     4801 cacgcttttt cctcctttat gtgccagcta atcaagctca atcaattcaa tagccttacg
     4861 attatcaagt tcatataacg tttgattaac tgactttata taactactct agaataacat
     4921 atttctacca aattatcgtt tgatagcgat tacccagaag taaaaaatgt acctatatcc
     4981 aatcataaat caagaccatc cctatcactg tctcaattag gaattgagta ggttaatgtt
     5041 cttcatcttg agtttttgtt agtagggact catttttgtg tactgagtct actataccac
     5101 aattatctga aaattccaat agcaatctga aaaaagccaa tcaaattggc tttttcagat
     5161 tctattgtct tctaacaaat tattctgcca ctacaccctt atcagctgtc aattcgatac
     5221 cctcataagc aagacctgta cccgaagctg agccgtattt tgtatcatag cttttcacac
     5281 gtttattaac agcagtaatt ttttctgact caaacgttgg aatagcaaat gcttgctcgt
     5341 gagcatattt ttgccaagcc ttatagttct caacgttttt cttatcatca aacgactctg
     5401 ctgagctgat agcttccaat aacttggtgt tttcatcgga cacgaaacgt gacatattga
     5461 aggctgcgat aggcccccat agaccacttg ggtttggatc gtaacctgtt gaccatccac
     5521 cagcatacat atcaatagca gcatcattag cctgaactga gttatagaac gacttacctt
     5581 caactgtacg tcctgtgtaa agttcgacat tcaagccaac ttctttccac caagcaatgt
     5641 attgttgtac aagcgcttcg ttagcttcag tacgtttacg agccgcaaag gtaatcttga
     5701 atgccttacc atctttgcct tcacggatac catcaccatc tacatctttg tagccagctt
     5761 catccaaaag ctttttcgct ttttcaggat tgtatgaata gccttccaac tctgaatcat
     5821 gaatatcgcc gaagaatgag ataatcaatg attttgcagg gtggtaaaga ccgttgtata
     5881 atgacttacc agctgtcttg gtatcaatcg cataggcaat cgcttgacga agtttcacat
     5941 cattcatctt ggcattttca tccataacgt tcttaccagc tgcttcgtca tatttaccaa
     6001 aattaaacga gatatactca taagacgact ctaactgacc aacgatattc aagttagaag
     6061 catccttata tgaatctaac tgatcaaccg gcatttctgc gatatcataa ttccccgctt
     6121 tcatttcaga aacaatagta tcaggagata cgatgtcaat cttcaatgag cttgtttttg
     6181 gtttcgtacc cttgaagaag tattcgtttg gtacgtaagt gatagactca ccattgacga
     6241 tttccttaat cttccacggc cccataccaa caagcttcgc agtacgtgag tattcgctct
     6301 tttcccagtc tgcaacaggg atgtctttat agatgtgttc tggttggata taggctggga
     6361 catcaccacc tgcatacatc attgaaggtg acatttcttt tacagttaat tctactgtat
     6421 agtcatcaac tttcttaata ccagagatgt ctgatgcttt tccatcaaca aattcttgca
     6481 taccttcaat attcaagaat ttatcatcaa aacgaatacc tgtatagtct ttgcttgcca
     6541 tcgacttaat tgtaaagatg tagtcgttga ttgtgaatga ctcaccatct gaccacttgt
     6601 aatccttacc agtcaagctg actgtgattt tcttgccttt tacatcaaat tcagccttgg
     6661 caagacctga gtcgtccaac ttacgttctc cgtcgtaacc gaacattgaa atatcaacca
     6721 taccaccaaa tgttgaatca gtagtattct cagtcaactc atcaattaaa agacctgatg
     6781 aagttgtagg agatacccaa gcatatttca attgagcatc tgcgactgct gttccatctt
     6841 gttttacttc agccgggaat gacaattcct gttttgctgc acctgattgt tttgaaccac
     6901 atgctgcaag aacagatgct gaaaggagag tcacacctgc aagtgcaaaa agtttcgttg
     6961 tctttttcat aaaacacctc tgttttcttt ttgtttgaca cttattacta tgtcttataa
     7021 aaatcattat atcataaatt tttcttaaat aaagtctttt tgtcagaaaa ttttgtaaaa
     7081 acatattttt tcatcatttt ctcatttttt acatgttttt tccaaatttt tctcacattt
     7141 cttgtgatat aatagaataa aataccccaa aaaggaatga ttatgcgtaa acttttacta
     7201 acactcacta caatccttgc tgttttttta acttccacac ctattttggc agaagatttt
     7261 tctgttgcag ccaagcatgc tatcgcggtt gaagtaagta gcggcaaaat cttgtatgag
     7321 caagatgccg aaaccaaagc aagcattgct tctatcagta agacattgag catttacctg
     7381 gtctacgaag cactggcaaa gggggaaatc actttagata ctatggtaga tatttctgat
     7441 tatccctata gcctcacttc taatactgaa ttaagcaatg tcaatctaga tgaacgctcc
     7501 tattctgtaa gagacctatt aaacgcttct ttaataacat catccaacag tgctattatt
     7561 gctctggcag aaaaaatagc cggtagcgaa gctgcattcg tggatcgaat gaaggcaaaa
     7621 gtccaagaat ggggaattac cgatacaaaa attgtcaatg tatccgggct agataatacc
     7681 gacttgggtg aaaatattta tccaggttcc agtcctgaag atgtaaatat gttttcagcc
     7741 ctagatgttg ctatcatcgc aagacgatta atactcgact atcctcaggt actcgacatt
     7801 acctcgctaa acgcctacga ttttggcggc tacacttact atagtaccaa ccaaatgctg
     7861 agcgacggca ctcacgctcg tggaggggtg gacggcttaa aaacagggac ctcaaactcg
     7921 gctggttcaa gttttcttgc aacaactcaa caagctggta tgcgcattat cacagtagta
     7981 ttgaatgcca atgatgggct gacctctcca gaaaatcgct ttgtcgcgac aaatgatttg
     8041 atgaactatg tttattctaa cttttcgctt gttacactag taaaaaaaag tgaagccttt
     8101 ggagatagta agataaaggt tttcaacggt gaaaaagaaa caagtcctgt tgttgcagca
     8161 gcagatttaa ctgttgttca acgaaatcaa actgataatg tccccaccgc aactttcaca
     8221 acggatatca aagaaattga tgctcccctc aaagcaggga ccttggtcag caaactacaa
     8281 ctgaaagatc aagatctcat tggaaaaggt tatatttccg agcaaactgg tgtcgatatg
     8341 attatcccta gcgatatgaa agaagcatcc tggccattct cttggtggaa tcaatttgtc
     8401 cgctatgtca atgaaaaatt ataaaaaaat agtatgtcga acgattttcg acatactatt
     8461 tttttattgt agagtgacaa ccgctactcc ttatctccag cctcggttgg agagtgagtt
     8521 ggtgagagtt cctgacagaa aatgacgagc gtggaaggta acaattccat tcgtcaattt
     8581 ataaagaaga gctactgccg tcgctcctca tctcctactt cagtggggag tttgacgggc
     8641 ttgaacagct ttaaagctgt tcaagttcgc ggcaaactat cccactgaac cctccatctc
     8701 ataggcaatc agtctgttga gttcgactgc gtattccatt gggagttctt ttgtgaatgg
     8761 ttcaacaaag cccatgacaa tcatctctgt agcttcggac tcggacaagc cacggctcat
     8821 gaggtagtag agctgttctt ctgagatttt tgatactttg gcttcgtgtt cgagggccac
     8881 ttgtgagttg tggatttcat taaatggaat ggtatctgat ttggaaatat catccataat
     8941 aatggtgtca cactcaatgt ggctgataga cttggctgag tttttcgcaa aagtgacttg
     9001 accacggtag ttgacttctc caccaccacg ggcaatggat ttggacacga tagaagatga
     9061 ggtgcgtggg gcgttgtgaa tcatcttagc accggtatcc tgtacctgac ccttgttggc
     9121 aaaggcaatg gacaacatgg ttccacgtgc cccttcacct tctaggtaaa ccgctgggta
     9181 tttcatggtc gtcttggcac cgaggttgcc gtcaatccac tcaactgtgg catttttctc
     9241 ggcacgggca cgcttggtta ccaagttata gacattgtct gaccagttct gaatggtggt
     9301 ataacgcata taggcacctt cgtgggcgat gatttccaca atcgctgcat gaagacttgc
     9361 cgttgagtag gtcggtgccg tacagccttc tacgtagtga acacttgccc cttcatctac
     9421 gatgatgagg gtgcgttcaa actgacctgt tccttcattg ttgatacgga agtaggtttg
     9481 gagtggaata tccagcttga caccttttgg tacatagatg aaggttccac ctgaccaaac
     9541 cgctgagttg agggcagcta gtttattatc tgacggcgga acaagttttc caaagtattt
     9601 tttgaagagt tctggatgtt ccttgagagc cgtgtcggta tccgtaaaga taatgccatg
     9661 cttgtcgtac tcttccttca tgttgtggta gaccacttct gattcatact gggcagaagc
     9721 acctgctagg taggcacgct cggcctctgg aataccgatg cgttcaaagg tttccttgat
     9781 tttgtctggt acatcatccc agctgcgtgc tggcttatct gacggttttt ggtaatagac
     9841 aatgtcatca aaatccagct cagacaagtc ggctccccaa gtctgcatcg gcattttctt
     9901 gaaggtttcg taggatttca aacggaattc caacatccat tcaggctcgc ctttgatacg
     9961 ggacatttca cgaatgactt cttcgttcaa acccttacct gtcgaagcca ccagttccac
    10021 gttctcgtca tggaaaccga atttgtattc tccaagatca atcggggttg gttcaattct
    10081 ttcttctgac ataatataag atactaagcc ccttaagaaa gcaaatgaaa aacaggaaat
    10141 cgacttcgtg tgcaaacaca cgcggagatt tatctttttt caaaagcttt tagggcgagt
    10201 tcaatttcat ttccaatcag aaactgaaca atcctttctg tatgattttc atttttgttt
    10261 attcgatgat gctcagtaag catcttcact tcgttcgatt gctttcttca agacactaaa
    10321 cttggttgga actaaagttc ctaaccaagt aacgcaaggt tctaatcaac cttgctaagt
    10381 ggcttactaa ttggctgatt ttggtaatat cgaccaaaat cgctcatgtc gcagttaccc
    10441 ttcattcagc actggaacga agtgacagtg ctttcttcag ggcattccac ggtaatgtgg
    10501 cacatttgat gcgttggggg aatttggcaa cacctgcgag gagggaggcg tctcccagtt
    10561 ccttctggcg tgggtcttct tgacctcgga ccatttgtga gaagatttct gctagttctt
    10621 gaatctgact gatttctttg ccaagcactg cttcagtcat catagaagct gatgcggttg
    10681 aaatggtgca gccaacgccg tcaaaagcaa tatcggtaat cacatctttt tcaatcttga
    10741 cggacaattc aatcacatcg ccacaggttg ggttgtggag ttctaacttt tccactccgt
    10801 ccaagcttcc gcgatgacga ggcgacttgg agtgttcaga cacaactgcc atataaagag
    10861 agtctaatct agatagggcc attgaaaaac tcctttgtct tgatgattgc ctcgaccaac
    10921 ttatcacagt cagccttggt attgtaaatg taaaaacttg ctcgtacagt agcaggcacc
    10981 tgcaaatatc tgagaagcgg ttgggcacaa tggtggcctg cccgcacagc aacaccttca
    11041 tagtccagag cagttgccac atcgtgtgga tgcaagtcgt ccaagttaaa ggcaataact
    11101 cccgtccgct tggacagatc ctgactgcca taaatggtca agcctggaat agcctgcaat
    11161 tttggaaaga catagtcaac cagttctgcc tcgtgggcct ggatagcgtc cataccaatt
    11221 tcggtcaggt aatcaatggc cgctcccaga ccaatcgcac ctgcaatatt gggcgttcct
    11281 gcctcaaact tccaaggcaa ttccttccaa gtagctgact gctcatagac aaagtcaatc
    11341 atttcaccgc cgaattcaac tggcgacatg agattgagca attcttcctt gccgtagaga
    11401 atgccaattc ctgtcggtcc caacatttta tgacctgaaa aggcatagaa atccacgtct
    11461 aattcttgca cgttgacgcc catgtgggga actgactggg ctccgtccac caccaagtag
    11521 gcaccgactt gatgcaccag ctctgctatt tccccaatag gaaccacgcc acctaggaca
    11581 ttggatacgt gggccaggga gacgaacttg gtcttagaag atagtagcga ccgcagatgg
    11641 tccatgtcta gctcgccgtc ttttagggtc acatagcgga gcttagcacc cgtttgctga
    11701 caggcttgct gccaagggat gatattggag tggtgctctt ggaccgagat gatcacttcc
    11761 tggtctggct ggagaatttc ctttgcaaac tgagccaccc agttaagact agtggtcgtt
    11821 cctctggtaa agagaatttc cttgctagac ttggcctgaa taaaatctgc caccttctgc
    11881 ctagccgcct cgtagcgagt agttgcccgt tccgaaaggg tgtgaacgcc acggtggaca
    11941 ttggcattgt ccttctggta ataatccgcc agcacatcta gtacctgctg cggtttttga
    12001 gtggtcgccg cattgtccaa atagaccagc ggctcatcgt taacaacttg gtctaggatt
    12061 gaaaattcct tgcgaatgcg ttccaaatcc atatcttatc tctttgttag tttttcttca
    12121 atcacggcaa tcagttggtc acgaacttcc ttaacaggaa tttctgtgat aacagagcct
    12181 aggaaaccac gaacaaccaa gcgttcagct gttgctcggt ccagaccacg actcatgagg
    12241 tagtacatgt cttctggatc cacctgaccg attgaggctg cgtgtccagc tgtgacctca
    12301 ttctcatcga taaggagaat tgggttagca tctgagcgag ccttatcaga caacatgagg
    12361 acacggcttt cctgctgggc atccgctcct ttagcaccgc ggacaatgtg tccgatgcca
    12421 ttgaaggtca aggttccact ttctaagata accccatgtt gcaggatgtg accgaccgaa
    12481 ttatgaccgt agttggtcac gcgcgtatcc acaccttgga cctgacgacc tgatgacagt
    12541 ccgacaactt tgaggttggc atggctaccg tttcctttta attcgctgtc caaatcggca
    12601 accacatttc cttcgttgag cagaccaatc gcccagtcaa tcgttgcatc gtttccgaga
    12661 tagccgcgac ggttgaggta ggtatccaaa tgcttgccaa ggcggtcaat ggccgcaaac
    12721 ttgatttggc taccagcaag ggcgattact tccacgacaa tattggctga agtcgttgct
    12781 gcgccgtcgc ccaaactttc aaagcgttct agataattaa gcttggcatt ttttccagcg
    12841 atgatgagga cacgtttatt aaaagcaact ggactagtgc tgtcttggta gaaaagggcc
    12901 tcaactggct ggtcgatttc aacattatct ggcacgtaga ggacagctgt tgcgttaaaa
    12961 taggctgtgt tataggcggc taatttgtgt tcatcgtagg ctacggcagc gccgagatac
    13021 ttttcaagta catctggaat gacatccata gccgatgcga agtcagtaaa gactacacct
    13081 ttctctacaa gggcaaccgg caactgttct agaatcgttt ggctgccaac ttgaaccaac
    13141 ataggattgt caccgatagc tgtaaaatct ggaactgccc cgatttcatc atttgtagct
    13201 aggcttccgt cacctagatt ccaacggtga aacttgaccc gctcgataac cggcaagtcc
    13261 agctctgcta ttttgtcaaa agccttaaga cgcaggtctg tcaaccaagt tggttctgcc
    13321 tgcaaggctg aaaattcttg aatcttttct ttggtcatag cttcctccaa agacttaaat
    13381 gtcatcttct ttgtagtcga tgccaagctc tgctgcgact tggacataac cttctttttc
    13441 caagcgttgt gccaattctg gtccgcctga cagaacaaca cgaccttcca tcatgacatg
    13501 gacaacatca ggagtgatgt agttgagcaa gcgttggtag tgagtaataa tcatggcacc
    13561 aaagccttca ccacgcatag catttatccc ctttgacacg actttaaggg catcgatgtc
    13621 caaacctgag tcaatctcat caagaagggc aaaagttggt tccaacatga gtaattgcag
    13681 aatctcattg cgttttttct caccacctga gaaaccttcg ttgaggtagc gctctgccat
    13741 ttcctctttc atgttaagga gctccatctt ttcatccaac ttagtaatga aatcacgaac
    13801 agaaatcttg tcttcgtctt ccttaccagc gttcattgcg gcacgaagaa attccgcatt
    13861 agtaatccct ggaatttctg acgggtattg catagccaag aaaagaccca tacgggcacg
    13921 ttcatcgact tctaattcta aaatattgac accgtcaaac agaatctcac cttgggtaac
    13981 ttcataactt ggattcccca tgatggctgc tgaaagggtg gatttccctg ttccgttcgg
    14041 tcccatgatg gctgcaattt cacctgtttt aagggtcaaa ttcacaccct tcaagatttc
    14101 tttgccttca atttccacat gaaggtcttt gatttctaat actgacatgc tgtgctcctt
    14161 ttcatttttg tcctcttcaa aaaccacatt aactgaccaa gctaactaga tacaccgata
    14221 agactcaact ttggcagtgg ggaaagagct cgaccattca tagaagagtc cgtcaacaag
    14281 tcctagtttt aagttgttga gctgggagtg ggaaagaact cgaccatcca tagaagagtt
    14341 cgttttccca cccccgcaca gttgattagg tcagatttgg agtgtaaaac acgaacaaat
    14401 ctgccaatca accactactg cgctaagatg ttgacactaa cgttgagaag cggtacaggg
    14461 cttgagccca gcttcactcc actggactgt taaacccaat caaccactac tgcgctgaga
    14521 tgttgacgct aactttgaga agtgatgcgg ggcttgagcc cagcctcttt tcttgttaat
    14581 gatgattttc agagagtgtt aatctataaa atagtctttt ctgacaattt taattaacca
    14641 tatccactat attatatcaa aaaaagagcc tgacggctct tatcttgttt agaaagattc
    14701 ttattttctt tttttctctt cacagcactt tttatacttt gcgatttttt cttgacggta
    14761 actactatta ccaataaacc gaagaagatt gagcaatgga gttctattaa taccaaagat
    14821 gccaatcaat tcacagagaa tctcaatccc cagtcccatg gtcaccaata ggagaatccc
    14881 ccctattcta ctcgaaacat tgagcaaaag agaggtcagg gagaataaga aagagatggc
    14941 gtaaatcacc aagactgtgc cacgatgagt aagtcccaga gagagcaagc gatgatgcag
    15001 atgcatctta tctgcttcat agattttttg cccagacaat tttcgacgaa tgatggctac
    15061 tacagtatcc gtaataggca ctccaagaat aatcatcgga gtaaccactg caacagctgt
    15121 cgaatttttc agtccttgaa gggacaagac tccaatcata aacccgatga agagggcacc
    15181 tgtatcgcca agataaatga tagcaggatt atagttatac ggtaaaaaac ctacaatcgc
    15241 cgcaaccaaa acaaagatgg ttaaggtcaa aaaaatattg ctatcatgca aaaagaaata
    15301 agacacaatt cccatcgttg tcagggaaat aatcgatact cccgaaacca gaccatccag
    15361 accatcaatc aagttgactg cattcgtaat ggaaacaatc caaaggaccg ttaatagaaa
    15421 agagagccag acaggaaatt gaaggaaagg tcctccaaaa ggaatcttaa agctatcaaa
    15481 acgaaattcc gtaaaaatcc aaataatcgt cgctgcagct agaataccaa acattttagg
    15541 agcaggcttt aactccttga catcatcaat gaatcccgta agaacgataa tgctggatgc
    15601 taggaccagg ggccagatat aatgcaagta agtgccatgg taattgacac gggtaacaat
    15661 tcctggtaaa aaccatagga cagaaatggt aaatgccaca aagatagcca gacctcccgc
    15721 tgaaggcatg ggcaccttat ttattcgccg tgcattggga ttatcaactg ctccaaccct
    15781 cagggacata aaacgaacca agggggtcgc aatggctgat atgaccatgg ttgtaataat
    15841 gaccattatg tattttagag caaaaggaat catactgtcg gaaccttcct aagctcctca
    15901 attgccgcaa gcggaagcat caaagttccg tgttcttgta aagcaggtct ggtcaactta
    15961 gtatcattgg taaattccaa cattcttgag agaatgtagc ctggatactg cttggaacga
    16021 ttttctacat tgataagaac tgtcaagtag tagtgaccat ccattttata taattccgat
    16081 tcttctactg gataatcaac cgtaccaaca aaagtaaaca gatcctctat cgttggaaat
    16141 tccaaaatat agtaaatata gcgctcctgc tcctcttcat ctgcttcttc ctcttgctct
    16201 acctcttcca aatgacgaac agctgttgca tccggtgcac ttttctcacg aacggtttgc
    16261 tccaaactct tgaaaaactc atctggagtc atacttgcga catcaccaag ttccgacaaa
    16321 tctgtaaatt catcaaaatt caagttctga tccaaatcag atttggtaac aaagatgtcc
    16381 acccgatctg gcttcggagt cacacgaaaa ctcagcatac cgctttctcg gaaagtcatt
    16441 ggtaaatcca attcatccaa aacagtgtaa aagaactcct ctgtcttttc ttgcggaatg
    16501 agaaagtccg aaagttccat tcctctctct tccaaatcat ctaattttat agtgattttc
    16561 aaggttgaat cactaatttg ctttactttc ataactacct cattcattga ttcatcaatt
    16621 ttttaaaatt gattgatcat tttcaatact catacatatc ttccaccatt atactaaaac
    16681 caagctcgaa agacaaaaga aaagcaggtc tccctgctct taaaataaaa atgtgataaa
    16741 ggcataaacc aataaaatcg cccctaaaat gatgcggtag taaccaaaga ccgtgaaatc
    16801 atgtttttta acaaagtctg tcaagaaacg aataacaact aaggatacca agtaagccgt
    16861 cacactagcg actagcaaga tccatacctg ctccatattc aggctattgc catctaagaa
    16921 atatttaaca gccttcaaac cactataacc aaacatggtt ggaatcccaa ggaagaaggt
    16981 aaaatctgcc gccacagatc ggctggtccc caaaataatc gctcccagaa tggtcgcacc
    17041 tgagcgacta gtccccggaa cgatgcttaa gacctggaaa cacccaatca acaaggcagt
    17101 tttataagac attttcgcta agtccgtcac ctgtggctct atacctctgt tacggttctc
    17161 aatccaaata aaggcaatac cgtagacaat caaagcaatc gcaatcggta ccataaaatt
    17221 gaaatgtgct tcaaaccaat tatccaacgg gactgcaatt aggatggacg gaatacaggc
    17281 aatgacaacc ttggcccaca attgccaagt caattgaata tcacgcttgg tttttccagg
    17341 ctgaaatgga ttcaattttt taaagtaaat agtcataact gctagaattg ctcctagctg
    17401 aatgacaata ttaaacattt ctaggaagtt cttactttgg tttaatttca cgaactcttg
    17461 aaccaaaatc aaatgccccg ttgaagaaac tggcaaccat tccgttaccc cttcaatgat
    17521 tcctaaaaat atagccttca acaattccaa tagcataaaa agctcctttt catcaattct
    17581 ctacattata tcataaaaaa actccctatt catagtacaa ggatattgaa atttgtcaga
    17641 atttttaata aaatggtgta atagcatttt aaaggagaca ctatgaaacg taaactcagt
    17701 atatttctgc tgaccctaat cgctgttttt tctgtaacaa caggggttcg ggcagacgaa
    17761 tacctgcggg tcggtatgga agctgcctat gcaccattta actggaccca agaagatgat
    17821 agcaacagtg ccgttcctat tgagggaacc aatcaatttg ccaacggata tgatgttcag
    17881 gttgcaaaaa aaatcgctgc atccatggat aaagaactct tggttgttaa aaccaagtgg
    17941 gaaggcttgg tccctgctct tacatctggt aaaatcgata tgattatcgc cggtatgagc
    18001 ccgacagaag agcgcaagaa agaaatcgcc ttctcagata gctactacac ttcaattcct
    18061 accctggttg ttcgttctga tagtcagtac gcaaacgcaa ccagcttgga agattttgct
    18121 ggcgcaaaaa tcactgccca gcaaggggtt tacctctatg atttgattga ccaaattgaa
    18181 ggggctaaca aacagactgc catgggagat ttctcacaaa tccgtcaagc tttagaatct
    18241 ggcattatag acgcctatgt ttctgaacgt ccagaaggtc gtacagcaga agctgcaaat
    18301 aaagctttca aaatggttga attggcagac agttttgaaa ccaatgccga agacgtgacc
    18361 attgctgtcg gtatgcgcaa agatgacgag cgtatcgctc aggtcaacga agtcttagca
    18421 actatttcag aagaagagca aatcgcactt atggatgata tgattgaaaa ccagcccgtt
    18481 gaagaagcca gcgagggcga aacacctagt ttcttcgccc aagtttggaa tattgttgtt
    18541 aacaactggc aacaacttct gcgtggaact gggatgacat tactcatttc catcctcggt
    18601 acaattatcg gtactgctat cggtctcctc atcggtgtct tccgtacagc tccaaaagca
    18661 gcaaacaagg cgcttgctat tggtcaaaaa gtgctcggtt ggattatcaa tatctacatc
    18721 gaaattttcc gtggtacgcc gatgattgta caatccatgg ttatttacta tggtaccgcc
    18781 caagcattcg gactcaatct tgaccgcaca cttgccgcta tcttcattgt atccatcaac
    18841 acaggtgcct acatgagtga gattgtccgc ggtggtatct ttgccgtcga taagggccaa
    18901 tttgaagctg ctactgctct cggatttacc cataatcaga ccatgcgtaa gattgtcctt
    18961 ccacaggtta ttcgtaacat cttaccagcg actggtaatg aatttgtcat caatatcaaa
    19021 gatacttctg tattgaacgt tatctcagtt gttgagctct atttctcagg aaatactgtc
    19081 gcaacccaaa cctatcaata tttccaaacc tttacggtta ttgctattat ctacttcatc
    19141 ctaaccttta ctgtgacacg tatcttacgc gcagttgaaa agtattttga tacagataca
    19201 tacacaacag gtgcaaacca aatgcaagtc gaggtgccac atgactaaaa atgtaattct
    19261 tgaaatcaaa aatctaaaga aatcatacgg acaaaatcaa gtcctcaaag acatctctat
    19321 tagcgttgaa aagggcgagg ttatctcaat catcggttca tctggttcgg ggaaatcaac
    19381 cttcctccga tctatcaacc ttttggaaac accaacagaa ggacagattc tataccacgg
    19441 acaagatgtt ttggctaaag gatatgattt gacgacttac cgtgaaaaac taggtatggt
    19501 attccaatcc ttcaaccttt tcaacaatct aaatgtattg gaaaatgcca ttgtagcaca
    19561 aactacggta ctgaaacgag atcgagctga ggcagagaaa atcgccaaag aaaatctcaa
    19621 caaggttggc atgaccgaac agtactggca agccaaacca agtcaactct ctggtggaca
    19681 gaaacaacgc gtggccattg cacgtgccct atctgttgac ccagaagtta tcctctttga
    19741 tgagccgact tctgctctcg atccagagat ggtcggggaa gttctcaaaa ccatgcaaga
    19801 tttggcaaaa tcaggattga cgatgcttat cgtaactcac gaaatggaat ttgcccgtga
    19861 cgtatctgac cgcgttatct ttatggataa gggtgtcatc gccgaagaag gcagccctca
    19921 acaaatcttt gaaaatccac aggaagaacg cacacgtgaa ttccttcagc gttttcttgg
    19981 ataaactcaa tctattccat agaagactat tacttaccag tttcaaagct ggtaagtttt
    20041 tttagactaa aaaaaagagg aattcgtaaa attcctcttt ttggacatct ctaaatgaaa
    20101 ccatttagat tagttttcaa atttcttgtg gtttttgtcg taaaaatcaa tcaaacccaa
    20161 ggcagttgca aatgaaatat tgtcaatctt agcgcgacct tgtgcaagag cgataactga
    20221 catttcacga gcatttgttt ccttactgat acggtaacct gtgattttct tttcacgaac
    20281 ccagccgaca acagcggcta ctttttcgta actagtcatt agaaacccct ttctttttta
    20341 ttcgtgcaat ttagtataat atgttttaac ctattttgtc aagtaaaatg ttcgtttttt
    20401 accatcattt tgccctaaga gatgatagta tttgcgtcct tatgtcttcg accccctccg
    20461 gattccccgg aaggaagata gtttgattac ctccttgtgc aaaattattg agagtatcca
    20521 agtattggtt ggtcagcaag atagacataa tctgctcttc agataggcta acatttgatt
    20581 ctttcagttc acgaatcgaa tctgccagtc cgtctacaat cgccttacgt tgttgtgcaa
    20641 tacctacacc atgcaagcga tccttttcag cttctgcttc tgctgctgtg acaattttta
    20701 tcttgtcagc ttctgccaat tcttgggccg caacccgttt ccgttgagct gcgttaattt
    20761 cattcataga ttgcttaacc tcggcgtctg gctctacctt ggtaattaag gttttgacaa
    20821 taacataacc gtaggttgac atttcttctg ctacttgttt ttgtacctca agtgcaatct
    20881 catccttttt ctcgaagagc tcatccagtg tcaatttagg cacagatgaa cgcagggcat
    20941 cttcaatata ggacttaatc tgtgcttctg ggtgcatgag cttgtaatag gcatccgtca
    21001 cattattttc atttactcga tattgagttg ccacattcat tgtgacaaaa acgttatcct
    21061 gcgtcttggt ttctaccaca atttcacttt gcaacatccg taattgaatg cgggctgcga
    21121 tgacatcgac tccaaatggt attttaaagt taatacctga agtagatgtt ttttggtatt
    21181 tcccaaagcg ctcaataata gcgaccgtct gctgcttgac aacgtatagc cctgaagcaa
    21241 tcaaaatcaa agcaatcagt acaaagaaca agaaactacc aataaaaaca attggaccaa
    21301 acaccataat gacctcctaa actagcattt tataaagcga atcattttca tgaagattga
    21361 tgtactgggg atcaaactct tccaagcgag aaataaactg cgtataatct gttttatctc
    21421 ctagggcaat accgattaga accggtcctg ttcccttatt ggcacgtttg atatattcaa
    21481 aacgagtaat atcatcattt ggccctagaa tatcatttac aaattcacga agagcccctg
    21541 gacgttgtgg aaaattaaca acaaagtagt gtttaattcc ctcgtagata agcgcacgtt
    21601 cctccatttc cggcatcctg ttgatgtcgt tattaccacc agaaatgata caacaaatgg
    21661 tttgcccctt gatttggtcc ttgactacct caagagctgc aatcgttgct gctcctgctg
    21721 gctcagcaac aatacccagc ttagaataga ggtctaaaat agtcccggaa atccaccctt
    21781 catccacacc aatcaggcga tctacgtatt tccgagccac ttcgtaggtc gacttaccga
    21841 ctttctgtac cgcaataccg tcagcaaatt tatcaatttg gtctaattta accggacgac
    21901 ctttatcaaa agccgctttc attgaccgtg ccccacttgc ttcaacacca acaatcttaa
    21961 tttcaggtgc atgttctttc agataggccg aaacgcctgc aaccagacca cctcctccta
    22021 tgggaactaa aatttggtca aaactaatgg tttgctcttc cgcttcttcc aagatttcat
    22081 aggctactgt tccctgacca gcctgcacat tttcatcatc gaatgggtct ataaatgttt
    22141 tcccactttc ctgagtataa tcttgtgctg ccttggctga ctcatcgaag gtatcaccta
    22201 cgagccgaat ctctacataa tctcctccga aaaatttaac ctgccctatt ttttgttgcg
    22261 gagttgtaat gggcataaaa atcgtagcag gaatttgcat ttcctgacag gtgtaggcca
    22321 caccttgagc atggtttccg gccgaagcac agaccactcc gcgtgacttc tcatcatctg
    22381 tcaattgtga aatagcataa taggctcctc gaattttaaa agagcgaaca cgctgttcat
    22441 tttctctttt taaataaata gttgcaccat atttttccga caagtatcga ctataatcca
    22501 agggggtacg tactaccacg cgcttaagaa cggagtatgc ttgttctaca ttttttgctg
    22561 taatcatagt tccattaatt tcttt
//
LOCUS       DBNFCO010000028        22400 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.028, whole genome shotgun sequence.
ACCESSION   DBNFCO010000028 DBNFCO010000000
VERSION     DBNFCO010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 22400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22400
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.028"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(32..970)
                     /gene="msrB"
                     /locus_tag="AC1PIV_000924"
     CDS             complement(32..970)
                     /gene="msrB"
                     /locus_tag="AC1PIV_000924"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002941039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HIP6611958.1"
                     /translation="MKEIYLAGGCFWGMEGYFSQIDGILDTSVGYANGQVETTNYQLL
                     KQTDHAETLYLAYDETRINLREILLYYFRVIDPFSVNQQGPDKGRQYRTGIYYTDEAD
                     LPTIEQVMTEQSQLFGGRPLAVEVEPLAHYIPAEDYHQDYLKKNPQGYCHIDLGQAKI
                     PLIDVADYQKPDQQVLKDSLTDLQYQVTQEAATERPFENEFWNSEQAGIYVDITTGEP
                     LFLSTDKFDSGCGWPSFTKPISKEVATYFQDKSHGMNRIEVRSRAGHAHLGHVFDDGP
                     RDKGGLRYCINSAALRFIPREEMEEAGYGLFLDLLK"
     gene            complement(1010..2539)
                     /locus_tag="AC1PIV_000925"
     CDS             complement(1010..2539)
                     /locus_tag="AC1PIV_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HIP6611959.1"
                     /translation="MSTISYKPLNLYRQFKTAAQEFPNVAIYFDKPYASFPELGLENT
                     YQTVFEAIQKRAAQFAAAGIGYGDKVILYKSPAFDTYLLAVAVTALGAVPVMISYHLP
                     SSNLDVFAERLEKSFIVYDQETEERVAGMTRTDLVTKIFLPQVLVQEAVAFEENLLPE
                     DVIQYMTHTSGTTGVPKLICHTAQTMGWRVAWQQTIFDKMTERGLLAFHISPVHSRYN
                     IGVSSAIGLGFPLYPLSSARKDDVERALALHRPSALETHPNNFVQWARLAKEKPEVFS
                     SIRYYHSTFDAINIGTLRAFLEASKEQDPVFMQVYGQSECGPMILRYHRLENLGTVSG
                     RDMGIGLEGYTEARITDAQGNPLPAGENGHIQFLSKGRAVTYYKEDARFQDNVYGAWW
                     DSGDYGCMTPEGTLLLKDRQVDLIEHIDSNLALEDLLLDKLDFLSEVVIIRDVNGAPQ
                     PIIALAEDAEMNWEAWWAMVADLPLLKEPILMAYDDIPRTATMKVQRLKMEAEMKEKN
                     L"
     gene            complement(2807..3121)
                     /gene="trxA"
                     /locus_tag="AC1PIV_000926"
     CDS             complement(2807..3121)
                     /gene="trxA"
                     /locus_tag="AC1PIV_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002941035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HIP6611960.1"
                     /translation="MVQVITDANFEVETQEGVVLVDFWAPWCGPCRMQAPILEQLADE
                     VDEDELRIYKMDVDENPNTARQFGIMSIPTLLFKKDGQVVKQVAGVHTKDQIKAILAE
                     IG"
     gene            complement(3328..3981)
                     /locus_tag="AC1PIV_000927"
     CDS             complement(3328..3981)
                     /locus_tag="AC1PIV_000927"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIP6611961.1"
                     /translation="MIIRKYQTSDEKGWVYCKALSYLFSPFFDDRETEKPELMTDVYD
                     HRVEWVAEVDGQIVGLIDIDIYTEECSQSYIYAPSKRTAYFTNLAVHPDFQGQGIAQA
                     LFEKAEQELRAQGVEKLAIFTREDDAANHLYQKWGGEVVCSDYLVVGAPQDVPTFRFG
                     IDLERGRLSFSDMEGQPVPYYLREGVYVVSEEAGLDLFDIEDVYQELTYVVDLTEKS"
     gene            complement(4005..6338)
                     /locus_tag="AC1PIV_000928"
     CDS             complement(4005..6338)
                     /locus_tag="AC1PIV_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009659728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0045910 - negative regulation of DNA
                     recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HIP6611962.1"
                     /translation="MNNKIIETLEFHKVRQKIEPYLLTEQGFEELRQLEPMVEVHRIQ
                     QAFDELTDIAQIFVENPYFSLAATSDIGPAMRRLELDTDLNIAELLAVKKVLEVSKSL
                     LDFYGNLENVSLSQLDKLFEKIELFPHLQGSLQSINDAGFVEDFASEKLARIRRKIRE
                     AEDQVRQVMQDILKTKGDMLSDSILASRNGRNVLPVKNTYRNKIAGVVHDISASGSTV
                     YIEPRAVVTLNEEISHLRAEERHELNRILQELSDMLRPHGGVIRNNAWLIGHIDFVRA
                     KHLFARDHQAVVPKLSEKQDIALLNVRHPLIAKPVPNDLYFGSQLTAIVITGPNTGGK
                     TIMLKTLGLTHLMAQSGLPILADKGSRVAIFKEIFADIGDEQSIEQSLSTFSSHMTHT
                     VEILRAADQDSLILFDELGAGTDPQEGASLAMAILDDLRLRGIKTMATTHYPELKAYG
                     IETSGIENASMEFDSNSLRPTYKFMQGVPGRSNAFEIARRLGLSDIIIQSAQSWTDTD
                     SDVNRIIEKLESQTVESRQRLDKIRDVEQENYKMNRALRKLYDELNRERENELNKARL
                     EAKEIVDMALAESEDILKNLHAAASLKPHQIIEAKAELKKLAPEVVDLSKNKVLKKAK
                     IKREAKVGDDIIVTAYGQRGTLTNQLKDGRWEAQVGLIKMTLAKDEFELVKAEKAEQP
                     KKRQVHTVKRANVRGPKARLDLRGKRYEEAMMELDEFIDQALLNNLAQVDIVHGIGTG
                     VIREGVTKYLRRNKQIKEFGYAPQNAGGSGCTIVTFK"
     gene            complement(6489..7037)
                     /locus_tag="AC1PIV_000929"
     CDS             complement(6489..7037)
                     /locus_tag="AC1PIV_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HIP6611963.1"
                     /translation="MISLAIILILAWSFYIGYSRGLVLQAFYSMGSIIALVVATATYK
                     KLASFLYLWVPFANATQGSSNYYFDEKYLFDLDMVFYAGLAFLLIYVLVYAIVRFIGI
                     FVHLLEAFNPDTKTTNLISGALAVLVTFISLQIVMVLLSTIPLAMIQDKLHSSFLANI
                     MIQYTPFTSSFLKSLWLSNIAG"
     gene            complement(7034..7345)
                     /locus_tag="AC1PIV_000930"
     CDS             complement(7034..7345)
                     /locus_tag="AC1PIV_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611964.1"
                     /translation="MANLNRYKFTFGEKQLTLTTEHDNLFMEEIERIAQEKYQAIKEK
                     MPTADPETLALLLAINALSVQLTREMAFEQKEQELASVKEKVLKKNVTLIDLDELEDK
                     V"
     gene            complement(7403..8116)
                     /gene="treR"
                     /locus_tag="AC1PIV_000931"
     CDS             complement(7403..8116)
                     /gene="treR"
                     /locus_tag="AC1PIV_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012774930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HIP6611965.1"
                     /translation="MKKYQEIYNDLKEKIRTNVYPAESSLPTEQQLQEIYGVSRDTVR
                     KALAILTEGGLIQKVQGRGSMVLKQEILNFPVSGLTSYQELTNVLQLSTKTDVVSLDM
                     ITVNSSLSHLTGFEPYSKVWKVVRTRSIDGKVSVVDTDYLAVDVVPELTTAIAEKSIY
                     EYLENKLGLDIAYAQKEITVEPTNREERELMQSKDDYLVLIKSRVYLGDTQQFQYTES
                     KHKIDKFRFVDFARRKHSL"
     gene            8350..10344
                     /gene="treP"
                     /locus_tag="AC1PIV_000932"
     CDS             8350..10344
                     /gene="treP"
                     /locus_tag="AC1PIV_000932"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015574 - trehalose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015771 - trehalose transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HIP6611966.1"
                     /translation="MGKFEKEAKQLLEAIGGKENVNAVTHCATRMRFVLADEKKANVK
                     VIEDIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNAI
                     QRVMTMLAEIFTPIIPALIVGGLILGFRNVLEGVQMEWLGQAMKDGQLVFDADGNPVW
                     NTIVQVSPFWNGVNHFLWLPGEAIFHFLPVGITWSVSRKMGTSQILGIVLGICLVSPQ
                     LLNAYAVPGTDAATIASDWSWNFGAFSIARIGYQAQVIPALLAGLALSYLEIFWRKVV
                     PEVVSMIFVPFLSLLPAIILAHTVLGPIGWTIGQWLSTVVLAGLTGPLKWLFGAVFGA
                     LYAPFVITGLHHMTNAIDTQLIADAGGTGLWPMIALSNIAQGSAVFAYFLMNRKNEKE
                     AQVSLPATISAYLGVTEPALFGVNVKYIYPFVAAMIGSSIAGLLSVTFNIQAASIGIG
                     GLPGILSIKAEYWGAFFMTMVVAIVVPMILTAVFKRTGAFSKKEETVEEVVAPTEAVV
                     ETGAAIELISPLTGQTKELSQATDPVFASGVMGQGVLIDPSEGILVAPVDGEVSVLFP
                     TNHAVGITATNGVELLMHIGMDTVGLEGKGFTAHVKQGDKVKAGDKLISFDIDVIKAA
                     GLIAETPVIVTNQTDFDTQVIGNLPRAISQGEAILTVTKN"
     gene            10425..12050
                     /gene="treC"
                     /locus_tag="AC1PIV_000933"
     CDS             10425..12050
                     /gene="treC"
                     /locus_tag="AC1PIV_000933"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009909185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008788 - alpha,alpha-phosphotrehalase
                     activity [Evidence IEA];
                     GO_process: GO:0005991 - trehalose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HIP6611967.1"
                     /translation="MTIDKRKVVYQIYPKSYKDTTGNGVGDLRGIIEKLPYLKELGID
                     MIWLNPFYPSPQRDNGYDISDYTAVNPDFGTMADFEEMVTVGKELGIEFMLDMVLNHC
                     STDHEWFQKALAGDKYYQDFFILRDQPTDWVSKFGGNAWAPFGDTGKYYLHLFDVTQA
                     DLNWRNPHIREELFKVVNFWKDKGVKGFRFDVINLIGKDEVLEDCPINDGKPAYTDRP
                     ITHDYLKMMNNATFGSEKGFMTVGEMSATTIENCILYTAPERKELSMAFNFHHLKVDY
                     KDGQKWTIMDFDFEELKHLFHTWGEEMSVGNGWNALFYNNHDQPRALNRFVDVENFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMDDYVDVESINAYQMLLDQGHTPK
                     QAFKIIQAKSRDNSRTPMQWDASDNAGFSTGTPWLKAGKSYQTINVEQEKTGPIFTFY
                     QELIRLRKELPLISEGDYKAAYKDSQKVYAFERLLNDEKLLVLNNFFAEEVELDLADD
                     YAHGQVLISNYPDNKLGKKIILKPYQALAIQVK"
     gene            complement(12464..13435)
                     /locus_tag="AC1PIV_000934"
     CDS             complement(12464..13435)
                     /locus_tag="AC1PIV_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012774929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HIP6611968.1"
                     /translation="MKNNKKMLYTSSLALSLFSTGMISTNVLAIEWAPRTVSEISPEI
                     VQEEGMMTYTVQYGDTLSAIASAMNIDMDLLAKINQIADINLIFPDTVLTTTVDQNNQ
                     VTQVEIEAPVQGNTNETVQATVDLTTNQVTVEDTVVPLDQISSVTDSAPVEEVVEQPV
                     AEAPVVEAPVEEVVEQPVVEAPVEEVVEQPVVETPQVTALSTTTTSTSAYDVGLQPQV
                     AAFRAEVANAFGITSFSGYRPGDSGDHGKGLAIDFMVPESSALGDQVAAYAVANLASK
                     NINYIIWKQRFYAPYDSIYGPAYTWNLMPDRGSITENHYDHVHVSFN"
     gene            complement(13844..14827)
                     /locus_tag="AC1PIV_000935"
     CDS             complement(13844..14827)
                     /locus_tag="AC1PIV_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012774928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family protein"
                     /protein_id="HIP6611969.1"
                     /translation="MEVQMKYKWATLGTGVIANELVQALQAMGGNLYSVANRTYDKGV
                     EFAQKYGIEKVYREIDEVFEDPEVDIIYISTPHNTHINYLRKALKAGKHVLCEKSITL
                     NSEELAEAIQLAEENQVVLAEAMTIFHMPIYRQLSEVVASGKLGELKMIQMNFGSYKE
                     YDMTNRFFNKNLAGGALLDIGVYALSFVRWFMIEKPNQVLSQVKLAPTGVDEQVGILL
                     SNDAGEMATIALTLHAKQPKRGTIAYDKGYIELYEYPRGQKAVITYTEDGSQEVIEAG
                     ETAKALSYEVADMEKAVAGIENTMHLAYTQDVMEIMTQLRKEWGLVYPEEM"
     gene            14912..15802
                     /gene="rnhC"
                     /locus_tag="AC1PIV_000936"
     CDS             14912..15802
                     /gene="rnhC"
                     /locus_tag="AC1PIV_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002941569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA];
                     GO_process: GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HIP6611970.1"
                     /translation="MNTVVLKASAQQKQAMMAHYDRYRQTSKNPYIEAFFKLTGASLS
                     IYTSGKVVFQGEMAEQEASRWGYEPESSGQATIPGQNLPMIGTDEVGNGSYFGGLAVV
                     AGFVRPEDHSFLKSLGVDDSKKMTDQKICQIAPLLKEKIPHQALLLSPKKYNEVIEQG
                     YNAVSVKVALHNQAIFLLLQKGVQPEKIVIDAFTSSQNYQKYLKKEANQFANPVTLEE
                     KAEGRYLAVAVSSIIARSMFLENLVQLGQLVGMHLPSGAGSKSDQVAASILKQYGMAG
                     LNQTAKLHFANTQKAQKLLK"
     gene            15812..16441
                     /gene="lepB"
                     /locus_tag="AC1PIV_000937"
     CDS             15812..16441
                     /gene="lepB"
                     /locus_tag="AC1PIV_000937"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HIP6611971.1"
                     /translation="MGAIQKTKRSPLVAFLAEWGIFLLFMAAFFASRYFIWNPVSVDG
                     HSMDPTLQHQEKLIMLKTSSIDRFDIVVASETDSDGKEKLIVKRVIGMPGDTIRYEND
                     VLYVNDQKVDEPYLDEYLAAFQKDKLQEVYSYNKQFQAVAQSAEAFTQDANGYVDFTV
                     TVPEGQYYLMGDDRLVSLDSRSVGTFSRENIKGEVVFRMWPLNRIGTVD"
     gene            16682..19171
                     /gene="recD2"
                     /locus_tag="AC1PIV_000938"
     CDS             16682..19171
                     /gene="recD2"
                     /locus_tag="AC1PIV_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0043139 - 5'-3' DNA helicase activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SF1B family DNA helicase RecD2"
                     /protein_id="HIP6611972.1"
                     /translation="MNEVYFTGTIDRIIFENPSNFYKILLLEIEETDADYDDYEIIVT
                     GTIADVIEGEDYRFYGNLVTHPKYGQQLQISRYERSKPTSAGLVKYFSSEHFKGIGRK
                     TAEKIVELYGEDTIDKILAEPEKLTQITGLSSKNMQAFVEKLRLNYGTELILAKLAEY
                     GIPNKLAFQIQDQYKEKTLQIIEENPYQLVEDVQGLGFTIADRIAENLGIASDSPQRF
                     RAGMLFSLIHRSMETGDTYVEARDLLEATLELLEKSRHTELDPAAVAKELTGLIADDK
                     VQQEGTKIFDNSLYFAEHGIHTNLTRLMGKNGFKPFPRADVEAAIAELESISSLTYDN
                     IQKEAIVQAITNPLFILTGGPGTGKTTVINGIIAVYAILHKIDLTRNREECPVLLAAP
                     TGRATRRMNELTGLPSATIHRHLGLVEGQEESYRDDYLDADFIIVDEFSMVDTWLANQ
                     LFQNISSQTQVLIVGDAEQLPSVSPGQVLADLLKIDKLPSITLERIYRQSDDSTIVTL
                     ASQIRQGALPSDFREKKADRSYFEAQNEQIPALIERIVGAAIKSGIPANEVQILAPMY
                     RGAAGIDQLNTMTQALLNPLEEGELEFLHNEQAFRQGDRVIHLVNDAEANVFNGDLGY
                     ITDLLPAKYTDSKQDEITINFDGSEVTYPRNEWYKITLAYAMSIHKSQGSEFQVVILP
                     ITRTSHRMLQRNLVYTAITRSKSKLILLGEISAFDYAVKNAGTVRKTYLVPRFQGEMA
                     EQESKESLIKKDESKTATTTQTQPPTQPDRKEQVKVVKENNQQLSLLDQDQPEKTSPQ
                     PTEYILTVDNLLTIDPMIGIEQADIEEFFKA"
     gene            complement(19210..21279)
                     /locus_tag="AC1PIV_000939"
                     /pseudo
     CDS             complement(19210..21279)
                     /locus_tag="AC1PIV_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636049.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
     gene            complement(21462..22271)
                     /locus_tag="AC1PIV_000940"
     CDS             complement(21462..22271)
                     /locus_tag="AC1PIV_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate isomerase"
                     /protein_id="HIP6611973.1"
                     /translation="MIEYYNFSKSELENHSRIPLIIKKNNEEIFISLALEMVELIKEN
                     NKKNEKTVIICPVGPVGHYPHFVRLVNQFKIDLSDVWFINMDEYLSEDLHWIDVVHPL
                     SFRGFMQKTVYSQIHPTLIMPEEQRIFPDPLDIDLISNKIKELGKIDLCIGGIGLNGH
                     IAFNEPDSTLTVQEFLKLESRVLPISVETKVMNCLTELKGAVEEVPNYCVTIGMSEIF
                     QAKKIRLAVFRDWHHAVIRKTVCSKPDTGFPSTLMQIHTNCSIYLNESLAN"
BASE COUNT         6329 a         5219 c         4562 g         6290 t
ORIGIN      
        1 ctttgcgaat agactttctg cgttcataaa tttatttaag caaatccaaa aacaggccat
       61 atcctgcttc ttccatttcc tctctcggta tgaaacgaag ggctgctgag ttgatacagt
      121 aacggagacc acctttatca cgcggtccgt catcaaagac atgacctaaa tgagcatgac
      181 cagcccgact acggacttcg atacggttca tgccgtggga cttatcttgg aaataagtcg
      241 caacttcttt gctgattggt ttggtaaagg agggccagcc gcagcctgag tcgaatttgt
      301 ccgtcgagag aaagagtggc tcgccagtcg taatatcgac gtagatgcca gcttgttcac
      361 tattccaaaa ctcattttcg aagggtcttt ccgtcgcagc ttcttgagtg acttgatact
      421 ggaggtcggt caagctgtct tttaagactt gctggtctgg cttttggtag tccgcaacat
      481 caatcagagg gatttttgcc tgcccaagat cgatatggca gtacccttgg ggatttttct
      541 tcaaataatc ctgatggtag tcttcggcgg gaatgtaatg tgcgagtggc tccacttcaa
      601 cagctagggg gcgtccacca aagagctggg actgctccgt catgacctgc tcgatggtcg
      661 gcaaatcagc ctcatctgtg taatagatac cagtccgata ctggcgaccc ttgtcaggtc
      721 cctgctgatt gacagagaaa ggatcaatga cgcggaaata gtagaggaga atttcccgca
      781 aattgatacg agtctcatca taggctagat agagcgtctc tgcgtggtct gtttgtttga
      841 ggagttgata attggtcgtc tccacctgtc cattggcata gccaacgctg gtgtcaagaa
      901 taccatcgat ctgggaaaag tagccttcca ttccccagaa acaaccgcct gctagataaa
      961 tttctttcat gtgaactcct tcttatctgc aagcgtggtt tcgtcactct tacagatttt
     1021 tttctttcat ttctgcttcc attttgaggc gttgaacctt catagtcgca gtacgtggaa
     1081 tgtcgtcata agccatcaag atgggctctt tcaatagtgg taggtctgca accatggccc
     1141 accaagcttc ccagttcatc tcagcatctt ctgccagagc gataatcggc tgcggtgcac
     1201 cattgacatc gcggataatc acgacttctg ataaaaagtc caatttatcc aacaataagt
     1261 cttccaaggc aaggttgctg tcgatgtgct caatgaggtc aacctgacgg tcttttagaa
     1321 gaagcgtgcc ctctggagtc atgcagccgt agtcaccact atcccaccaa gcaccgtaca
     1381 cattatcttg gaagcgggca tcttctttgt agtaagtcac agcacggcct tttgacagga
     1441 actggatatg cccgttttct ccagctggga gaggattccc ttgggcatct gtgatacgtg
     1501 cttctgtgta accttccaga ccaatcccca tatctcgtcc gctaactgtt cctaggtttt
     1561 ccaagcgatg gtaacgtaaa atcattggac cacattcact ttgaccataa acctgcataa
     1621 agactggatc ttgctcttta gaagcctcca agaaggcgcg aagcgtacca atattgatag
     1681 catcaaaggt tgaatggtaa taacgaatgc tactaaagac ctctggtttt tccttggcca
     1741 atcttgccca ttggacaaag ttattaggat gggtttccag agcacttgga cgatgaagag
     1801 caagtgcccg ttcaacatca tcttttcttg cagaagaaag tgggtagagg gggaatccta
     1861 acccaatcgc cgacgacacg ccgatattat agcgtgaatg tacaggggag atatggaagg
     1921 ccagcaagcc tctctccgtc atcttgtcaa aaatagtttg ttgccaagct actcgccagc
     1981 ccatggtctg tgctgtatgg cagattagtt ttggaacacc tgtcgtccct gaagtatgag
     2041 tcatgtattg aatgacatct tctggcagga gattttcttc aaaagcaact gcttcttgca
     2101 ctaggacttg gggtaaaaat atctttgtga ccaggtcagt tcgagtcatt cctgctacac
     2161 gttcttctgt ttcttggtcg tagacaatga aagacttttc caatcgctcc gcaaacacat
     2221 ctaaattcga agatggcaaa tggtaggaaa tcataacagg aacagcaccc aatgccgtta
     2281 ccgctactgc taacaaatag gtatcaaagg ctggactctt atatagaatt accttgtccc
     2341 catagccaat acctgctgct gcaaattggg cagctctttt ttgaatagct tcaaaaactg
     2401 tttgataggt attttccaat cctaattcag ggaaagatgc gtagggtttg tcaaaataaa
     2461 tggcaacatt tggaaactct tgagccgctg ttttaaactg acgatagaga tttaatggtt
     2521 tgtaactaat agttgacata tctaaccttt ctaaaatgac aatgataagg ttattataac
     2581 atcttgtgcc aaccttcaca atcttatatc ttagcaaata tcgtcattta gtttttcttt
     2641 tattacttcg acgagctagg aaatatcgtt tctatatttc caacctccca ctatctccca
     2701 gatagttgga gcaaatacta aaagactata ttagaaaata atcacaaaag taagtctgat
     2761 tataaaaaaa gcaagtagtc gatccaccac ttgctttcat tttcaattaa ccaatctctg
     2821 ccaagatagc tttgatttga tctttcgtgt ggacaccagc aacttgtttc acaacctgtc
     2881 catctttttt gaacaaaaga gttgggatag acatgatacc aaactgacga gctgtgtttg
     2941 gattctcatc aacatccatc ttgtaaatac gcaattcatc ttcgtccact tcatctgcca
     3001 attgctccaa aattggtgct tgcatacgac aaggaccaca ccatggtgcc caaaagtcaa
     3061 caaggactac gccttcttgt gtttcaactt caaagtttgc atctgtaata acttgaacca
     3121 taattttctc cgtttctgtt tttctactat cattctacac caaaaaaaaa cagaaagcga
     3181 atttttgcta cgggatgaag catgagataa acgtacctat aagaatttca gttgtaaaaa
     3241 ataggtatag ctaaactaga ccgcaggagg acgagggggg aatcacgtac cagattcatt
     3301 tacaaaaaga aaaaagttga aaatgtttca acttttttct gttaaatcca ccacataggt
     3361 taattcttga tagacatctt ctatgtcaaa gagatccaag ccagcttctt cgctgactac
     3421 ataaacacct tctctcaaat agtagggaac tggctgacct tccatatctg aaaaggacaa
     3481 tctacctcgc tctaaatcaa ttccaaagcg gaaggttgga acatcttgtg gcgctccgac
     3541 cactagataa tccgaacaga ctacctcacc accccatttc tgatataaat ggttggctgc
     3601 atcatcctca cgagtaaaga tggctagttt ctctacacct tgcgctctca actcctgctc
     3661 tgctttttca aaaagcgcct gggcaatgcc ctgcccttga aaatcagggt ggactgctag
     3721 gttagtaaaa taagctgttc gcttacttgg tgcgtaaata taagactggc tgcactcctc
     3781 agtgtaaata tcgatgtcga ttagaccaac aatttgtcca tctacttcag ccacccattc
     3841 cacacgatga tcataaacgt ctgtcattag ttcgggcttc tctgtttctc tatcatcaaa
     3901 gaatggagag aagaggtagc tgagtgcctt acagtaaacc cagccttttt catcactggt
     3961 ttgatatttt ctgataatca taagaatctc ccatcggttg attgctattt aaacgtcaca
     4021 atagtacagc ctgatccacc tgcattttgt ggggcatagc cgaactcctt gatctgcttg
     4081 ttgcggcgta ggtacttggt caccccttct cggatgactc cagtaccaat accgtggaca
     4141 atatcgactt gggctaggtt attgagaagg gcctggtcga taaattcatc cagctccatc
     4201 atagcctctt cgtaacgttt gccacggaga tctaagcggg cttttggtcc tcgtacattg
     4261 gcacgtttga ctgtgtgaac ctggcgtttc ttaggctgct ctgccttttc cgccttgact
     4321 aactcaaact catctttagc caaggtcatc ttaatcaagc caacctgagc ttcccaacgc
     4381 ccgtccttga gctgattggt caaggtcccg cgttgtccat aagctgtaac gataatgtca
     4441 tcgcccacct tggcttccct cttaatttta gctttcttca gaaccttgtt tttagacaga
     4501 tccaccactt caggcgccaa ctttttcagc tctgccttgg cttcgataat ctgatggggc
     4561 ttaagactag ctgcagcatg gagatttttg agaatatcct cgctttctgc caatgccata
     4621 tctacaattt ccttggcttc caagcgtgcc ttgttgagct cattttcccg ctcacgattg
     4681 agctcgtcat agagcttgcg gagggctcgg ttcatcttgt aattttcttg ctccacatca
     4741 cgaatcttat ccagacgttg acgactttca accgtctgac tttccaattt ctcgataatg
     4801 cggttcacat cgctatctgt atccgtccaa gattgggctg actggataat aatatcagat
     4861 agaccaagac ggcgggcaat ttcaaaggca ttggagcgac caggaacacc ctgcataaac
     4921 ttataggtcg gacgcaggct attgctatca aactccatgc tggcattttc aataccagag
     4981 gtttctatcc cgtaggcctt aagctcaggg tagtgggtgg tcgccatggt cttgatcccc
     5041 cgcagacgaa ggtcatccaa aatagccata gccaaagacg caccctcctg cggatctgtc
     5101 ccagctccca actcgtcaaa gagaatgaga gaatcttgat cagctgctct taaaatttcc
     5161 accgtgtggg tcatgtgact ggagaaggtt gataaactct gctcaatcga ctgttcatcc
     5221 ccaatatccg caaaaatttc tttgaagata gctacccgac tgcccttatc agccaagata
     5281 ggcaaaccag actgggccat cagatgggtc aatcccaagg tcttaagcat gatggtctta
     5341 ccacctgtgt tgggacctgt tatcacgata gccgtcaact gactaccgaa ataaaggtca
     5401 tttggtacag gcttagcaat gagcggatgc cgaacgttga gaagggcaat atcctgcttc
     5461 tcagatagtt tgggtacaac tgcttgatga tcacgcgcaa agagatgctt agcacggacg
     5521 aaatcaatat gtccgataag ccaggcattg ttacgaatca cgccaccatg cggacggagc
     5581 atatccgaca attcctgcaa gatacggttg agctcatggc gttcttctgc acgtaggtga
     5641 ctgatttctt cgttcaaggt caccactgcc cgcggctcaa tataaacggt cgaacccgaa
     5701 gctgaaatgt catggacaac ccctgcaatc ttattgcgat aggtattttt aacaggaagg
     5761 acattgcgtc cattacggct tgccaaaatg ctatcggaca gcatgtcgcc cttggtcttc
     5821 aaaatatcct gcatgacctg acgaacttga tcttcagctt cacggatttt tcttcgaata
     5881 cgagccagct tttctgaggc aaaatcctct acaaaaccag catcattgat ggactggagg
     5941 gagccctgta aatgtggaaa aagctcaatc ttctcaaaga gtttatccaa ctggctaaga
     6001 ctgacatttt ccagatttcc ataaaaatcc aagagagatt tagaaacttc caagaccttt
     6061 ttaacagcta ataattcagc gatattgagg tctgtatcca attccaaacg acgcatggct
     6121 ggaccgatgt cactagtagc agccagactg aaatagggat tttccacaaa aatctgcgct
     6181 atgtctgtca actcgtcgaa ggcctgttgg atacgatgga cttccaccat gggctccaac
     6241 tgtcgtaatt cttcaaagcc ctgttccgtc aagagatagg gctcaatttt ttgtcttacc
     6301 ttgtgaaatt caagggtttc aataatttta ttattcatat attcctactt agtcttttcc
     6361 ttagctttat ctcattatca aaacaataaa agataaaaat atagtctttc ccactcatca
     6421 aatcaacaac gtctggtttt gattttcgaa gagtattata aatgacgata aaaaggataa
     6481 ggcctccctt accctgctat attactcaac cagagagatt ttaaaaagct actagtgaat
     6541 ggtgtgtact gaatcatgat gttggcaaga aaactactgt gcaatttatc ttgaatcatc
     6601 gctaacggaa tagttgatag caagaccatg acaatctgaa gagaaataaa agtcaccaag
     6661 acagccaagg cgccgcttat gagattggtc gtttttgtat caggattaaa agcctctaat
     6721 agatggacaa atattcctat gaaacgcaca atagcgtaaa ccaagacgta tatcaaaaga
     6781 aaggccaatc ccgcataaaa taccatatct aggtcaaaga gatatttctc atcaaaatag
     6841 tagttggagc tcccctgagt agcattggca aatggcaccc agagataaag gaaggatgcc
     6901 aattttttat aagtagccgt cgcaaccacc agggcaataa tacttcccat gctatagaag
     6961 gcctgtagaa ctagaccacg actgtagcca atgtagaaac tccatgccaa aatgagaata
     7021 attgctaatg aaatcatacc ttgtcctcaa gctcatctaa gtcaatcaag gtcacattct
     7081 ttttcaaaac cttttctttg acgcttgcaa gttcttgttc cttttgttca aatgccatct
     7141 cgcgcgttag ttgaacggat agagcattga ttgccaacaa aagcgcgagg gtttcagggt
     7201 ccgccgtcgg catcttttct ttgatggctt ggtatttttc ctgtgcaata cgctcaatct
     7261 cttccatgaa taaattatca tgctcagttg tcaaagttaa ttgcttctcg ccaaatgtaa
     7321 atttatatcg atttaagttt gccatatctt acctcttctt ctatctatta tagcgtaaaa
     7381 aacttgattt ggctaatctc tcctataaag aatgctttct acgagcaaaa tctacaaagc
     7441 ggaatttatc aattttatgc ttgctttctg tatattggaa ttgttgggta tcaccgagat
     7501 agacacgaga tttaatcaag accaaataat catccttcga ttgcattagc tcacgctctt
     7561 ctcgattggt cggctctacc gtaatctctt tttgtgcata agcaatatca aggcctaact
     7621 tattttctag gtattcgtag atggattttt cagcaatagc agttgtcaac tctggcacga
     7681 catcgacagc aagataatct gtatccacaa cggagacctt accgtcaatc gaacgtgtac
     7741 ggacaacttt ccacaccttg ctatacggct caaagcctgt caagtgcgaa aggctactat
     7801 taacggtaat catatctaag ctgacaacat ctgtcttggt agaaagctgg agaacatttg
     7861 tcaattcctg ataggaagtt aaacctgaaa ctgggaaatt gagaatttct tgcttaagga
     7921 ccattgaacc acgcccttgc actttttgaa tcaaacctcc ctcagtcaaa atcgccaacg
     7981 ccttacgaac cgtatcacga ctaacaccat agatttcctg aagctgctgt tctgtcggta
     8041 gggagctttc tgccggataa acatttgtcc gtattttttc ttttaagtca ttataaattt
     8101 cttggtattt tttcatcatt tcctcgcaaa ttcatctgtc aaataacata caactatcaa
     8161 cattataaca aaattcattt caaaattaaa aaaaactaag caaaaacgct tgcattattt
     8221 tttgaaatcg gatacaatga taacacaaaa gaaatttgtc cgtacaaatt tcaaaaaagg
     8281 acatgcttcg agagatgtct aaaaaatata gggtgacgga ttccataagc cgtctagaag
     8341 gaaaaatata tgggaaaatt tgaaaaagaa gccaaacagc tcctagaagc tattggcgga
     8401 aaagagaatg tcaatgcagt aacacactgt gcaacgcgca tgcgctttgt tcttgcagat
     8461 gagaaaaaag caaacgtaaa agtcatcgaa gacattccag cagtaaaagg aacatttacc
     8521 aacgctggtc aattccaagt catcatcggt aacgatgtac caatcttcta caatgacttt
     8581 acagctgtgt ctggtatcga aggcgtatca aaagaagctg caaagtcagc cgctaaaagt
     8641 aaccaaaatg ccatccaacg tgtcatgacc atgctggcgg aaatcttcac accgatcatt
     8701 cctgccctta tcgtcggcgg tttgattctc ggtttccgta acgtcttgga aggtgttcag
     8761 atggaatggc ttggacaagc tatgaaagat gggcagttgg tcttcgatgc tgatggtaac
     8821 cctgtatgga acaccatcgt tcaggtttct cctttctgga atggtgtcaa tcacttcctc
     8881 tggttgccag gtgaagccat cttccacttc ttgccagtag gtatcacttg gtccgtatct
     8941 cgtaaaatgg gaacttcaca aatccttggt atcgtccttg gtatctgttt ggtttctcct
     9001 cagttgctca acgcttatgc tgtacctggt acagatgcag caaccattgc cagcgactgg
     9061 tcttggaact tcggtgcatt tagtattgcc cgtatcggtt atcaagcgca agttatccct
     9121 gccctccttg ccggtttggc actgtcttac ctagaaatct tctggcgtaa ggttgttcca
     9181 gaagtggtct caatgatctt cgtaccattc ctatcacttc ttcctgcaat catcttggct
     9241 cacactgtcc ttggtcctat cggttggaca atcgggcaat ggttgtcaac agttgtatta
     9301 gctggtttga ctggcccatt gaaatggctc ttcggtgctg tattcggtgc cctttatgcg
     9361 ccattcgtta tcactggtct tcaccacatg accaacgcca tcgataccca attgattgcg
     9421 gatgctggtg gtactggtct ctggccaatg atcgcccttt ctaacattgc acaaggttct
     9481 gcagtatttg cttacttcct catgaaccgt aaaaatgaaa aagaggcaca agtttctctt
     9541 cctgcaacaa tttctgctta ccttggtgtt actgaaccag ccctctttgg tgtcaacgta
     9601 aaatacattt acccatttgt agctgctatg attggttcaa gtatcgcagg cttactctct
     9661 gtaaccttca acatccaagc agcttctatc ggtatcggtg gtcttccagg tatcttgtct
     9721 atcaaggctg aatactgggg tgcattcttt atgacaatgg ttgttgcgat tgttgtccca
     9781 atgattttga cagctgtttt caaacgtaca ggtgcatttt caaaaaaaga agaaactgtt
     9841 gaagaagttg tagctccaac tgaagcagtt gttgaaactg gcgctgctat cgaattgatt
     9901 agcccactta ctggtcaaac caaagaattg tcacaagcta ctgatcctgt atttgcatca
     9961 ggtgtcatgg gccaaggtgt ccttattgac ccgagcgaag gtatcttggt tgctccagtc
    10021 gatggtgaag tatctgtcct cttcccaact aaccatgctg ttggtatcac tgctacaaac
    10081 ggagttgagc tccttatgca cattggtatg gatactgttg gattggaagg caaaggcttc
    10141 acagctcacg tcaaacaagg cgacaaggta aaagctggtg ataaattgat tagctttgac
    10201 atcgatgtca tcaaggctgc tggtctcatc gctgaaacac cagttatcgt gaccaaccaa
    10261 actgactttg acactcaagt tatcggaaat cttcctcgtg ccatctcaca aggcgaagct
    10321 attctgacag ttacaaagaa ttaatgttct aggagggcgc aaggtaactt gcacctccta
    10381 tcattgctta tgcaagaagg aaaaatcaag aaagagagag caaaatgaca atagacaaac
    10441 gaaaggttgt ttatcaaatc tacccaaaat cttacaagga tacaactgga aatggtgtag
    10501 gggatttacg aggaattatt gaaaaactcc catatttaaa agagctaggt attgatatga
    10561 tttggctcaa tcccttctac ccaagtcctc agcgggacaa cggctatgat atttctgatt
    10621 atacagctgt caatcctgat tttggcacca tggctgactt tgaagaaatg gtgactgtcg
    10681 gcaaagaact aggcatcgaa ttcatgctag acatggtcct caatcactgc tcaaccgacc
    10741 acgaatggtt ccaaaaagcc cttgccggcg acaaatatta ccaagatttc tttatcctgc
    10801 gtgaccagcc aactgactgg gtgtccaagt ttggtggcaa tgcctgggct ccttttggag
    10861 atactgggaa atactacctc cacctctttg acgtgaccca agccgacctc aactggcgaa
    10921 atcctcatat ccgtgaagaa ctcttcaagg tggtcaactt ctggaaagac aagggtgtca
    10981 aaggcttccg cttcgacgtt attaacctga ttggtaagga cgaagtccta gaagattgcc
    11041 caattaatga cggcaagcca gcttacaccg accgcccgat tacccacgat tacctcaaga
    11101 tgatgaacaa tgctactttt ggtagtgaaa agggcttcat gaccgttggg gaaatgtctg
    11161 ccaccaccat tgaaaactgt atcctctaca cagctcctga acggaaagaa ttgtccatgg
    11221 ccttcaactt ccaccacttg aaagtggatt acaaggacgg gcaaaaatgg accatcatgg
    11281 actttgactt tgaagaactc aaacacctct tccacacttg gggtgaagaa atgtccgtcg
    11341 gaaatggctg gaacgccctt ttctacaaca accacgacca acctcgtgcc ctaaaccgct
    11401 ttgttgatgt ggagaatttc cgcaaggaag gagcaaccat gttggcagcc tctatccacc
    11461 tatcacgcgg cacaccttac atctacatgg gtgaggagat cggtatgatc gaccctgact
    11521 acgatagcat ggacgactac gtggacgtgg agtctatcaa tgcctaccag atgctcttgg
    11581 accaaggtca cacgcctaag caggccttca agattatcca ggccaagtcc cgtgacaatt
    11641 cccgcacccc gatgcaatgg gacgcttctg acaatgcagg cttctcaaca ggcactcctt
    11701 ggttgaaagc tggcaaatcc taccaaacga ttaacgttga acaggaaaaa acaggcccaa
    11761 tctttacctt ctaccaagaa ctcatccgcc tgcggaaaga actccctctg atttcagaag
    11821 gggactacaa ggcagcctac aaggatagcc agaaagtcta cgcctttgaa cgcttgctaa
    11881 atgacgaaaa actgttggtc ctcaacaatt tctttgcaga agaggtcgaa ttagacctgg
    11941 cagacgacta tgcccacggc caagtcctca tcagcaacta tcctgacaac aaactaggca
    12001 aaaaaatcat tctcaaacct taccaagcat tggcgattca agttaaataa acgataaaac
    12061 atccgaaaat aacactctac atgtcaattt taattttcct aaaattagaa cccgccttca
    12121 cagctcagta ggttacttgt gaaggcaagt tcttggttta aggtttcttt taggaatata
    12181 ttttagactg taatttgcgc acgaaacagc tatctggggg gagatagttg tttcttcttt
    12241 tatagtcatt tgaattaact ttgatacatc gtcactttcg gcttgccgta ctctacgaaa
    12301 gtgacttgtt tcgcaagtct tatttccaac ctagaacagc ctctaggctg ttctagctac
    12361 ctgcacctca gttccttgtc tgaaagttaa ttcattcgac tatattacta catataaagc
    12421 aataaccgtt tcagataagg ctgaaacggt tatttttgta agtctaatta aaagatacat
    12481 gcacatgatc gtagtggttt tctgtaatgc taccacggtc tggcatcagg ttccatgtat
    12541 aggctggacc atagatactg tcatacggcg catagaagcg ctgtttccaa atgatgtagt
    12601 tgatattttt agaagctaag tttgcaactg cataagccgc cacttgatct cctagagctg
    12661 agctctcagg caccataaag tcaattgcca atcccttacc atggtcgcca gaatcaccag
    12721 gacggtaacc tgagaaagaa gtaataccga aggcattagc tacttctgcg cggaaggctg
    12781 ctacctgagg ttgcaaaccg acatcataag cacttgtact tgttgtagtg gttgataggg
    12841 ctgtcacttg tggagtttca actacaggct gttctacaac ttcctctaca ggtgcctcaa
    12901 ctacaggctg ctctacaact tcctctacag gtgcctcaac cacaggtgct tctgctacag
    12961 gctgttctac aacttcctct acaggcgctg agtcggtaac tgatgaaatt tgatccaagg
    13021 gaacaaccgt atcctcaacc gttacttgat tggttgttag gtcaacagtt gcctgaacgg
    13081 tctcatttgt gtttccctga acaggagctt caatctcaac ctgagtcact tgattgtttt
    13141 ggtcaacagt cgtcgtcagt actgtatcag ggaaaatcaa gttgatatct gcaatttgat
    13201 ttattttcgc cagcaagtcc atatcaatat tcatagctga ggcgatggca gataaggtat
    13261 ctccatactg aacagtatag gtcatcattc cttcttcttg tacaatttct gggctaattt
    13321 cagaaacagt acgtggagcc cattcgatag ctaaaacatt tgtcgaaatc atccccgtac
    13381 taaagaggga aagagccaat gaagatgtgt ataacatctt cttattgttt ttcatgatgg
    13441 atgtttttct cttgcgacgc atatgttgtg gtttatttgt tctcttacgt ttcataatct
    13501 tattccttca ttatttttga gatggttcta tcttacctaa attaaatctg aaaaacaagc
    13561 cttcaaccgt tcttttaaat aaactgtctc cactatgtaa tcttaggact tttctgtcac
    13621 acaatcaata taaatgtcat ctgactgtca tattattagg taatactcaa tgaaaatcaa
    13681 aaacagactc ggaaacgcag atgcagatag aacaaaactt catcaaatca agtcaacaac
    13741 gtctggattt tcgaagacta taagtaaaaa ataagagtaa ggcagtaatc caacaattgg
    13801 ctactaactc actctcattt ctattttcgg attagtcaag atcctacatt tcttcaggat
    13861 aaaccaagcc ccattcttta cggagttggg tcatgatctc catgacatct tgggtgtagg
    13921 ctaggtgcat ggtgttttcg atgcctgcga cagctttttc catatccgcc acttcataag
    13981 aaagagcctt ggctgtctcg cccgcttcga ttacttcttg actaccgtct tcagtatagg
    14041 taatgactgc tttctgacca cgtgggtact cgtaaagctc gatgtagcct ttatcgtagg
    14101 caatagtgcc ccgttttggc tgtttggcat ggagggtcag ggcgatggtc gccatttctc
    14161 ctgcatcatt gctgagcaaa atccctacct gctcgtccac acctgtcgga gccaatttga
    14221 cctgagatag gacttgattt ggcttttcta tcataaacca acggacaaag gacagagcgt
    14281 agacaccaat atccaagagg gcaccgccgg ccaagttctt attgaaaaag cggttggtca
    14341 tgtcatattc cttgtagctg ccaaagttca tctgaatcat cttcaactct ccaagcttgc
    14401 cactggcaac cacttcgctc aactgacgat agattggcat gtggaaaatg gtcatggcct
    14461 ccgccaagac gacctgattt tcctcagcta attgaatagc ttctgctaat tcttctgaat
    14521 taagcgtaat agacttttca cagaggacat gctttccagc cttcaaggcc tttctcaaat
    14581 aattgatatg ggtattgtga ggcgtagaaa tatagataat gtctacttca ggatcctcaa
    14641 acacttcatc gatttctcga taaactttct cgatgccata tttttgcgca aattccacac
    14701 ccttgtcata ggtacggttg gctaccgaat aaagatttcc tcccatagcc tgcaaggcct
    14761 gaaccaattc gttggcaatg acacctgttc ccagagtcgc ccatttatac ttcatttgca
    14821 cttccatagt gtacctcact ttcttctacc attatagtaa attccaccct tttctgcaca
    14881 ctctaactag catttgtgtt acaataagaa catgaatacc gttgtactaa aggcatctgc
    14941 ccagcaaaaa caagccatga tggctcacta tgaccgctat cggcagacca gcaaaaatcc
    15001 ttacatagaa gcatttttca aactgaccgg tgcaagcctg tccatctaca cttctggaaa
    15061 agtcgttttt cagggggaaa tggcagagca ggaagcaagc cgttggggct atgagccaga
    15121 aagctctgga caggcgacca tacctggtca aaacctgccc atgattggta ccgatgaggt
    15181 tggaaacggg tcttattttg gaggtttggc agtcgttgct ggttttgtcc gcccagaaga
    15241 ccattccttt ctcaagtcgc ttggtgtcga tgattccaaa aaaatgacag accaaaaaat
    15301 ctgccaaatc gcccctctct taaaagagaa aatcccccac caagctctgc tattgtcacc
    15361 gaaaaaatac aacgaagtca tcgagcaagg ctacaatgcg gtgtctgtca aggtcgccct
    15421 acacaatcag gctattttcc tactcttgca aaagggtgtc cagcctgaga agattgtcat
    15481 tgacgccttc acttccagtc aaaattatca aaagtacttg aagaaggaag ccaaccaatt
    15541 tgccaacccc gtcactctag aagaaaaggc tgagggcagg tatctggctg tggcagtatc
    15601 ttctatcatt gcaagaagta tgtttttaga aaatcttgtc cagcttggtc aactagttgg
    15661 aatgcatctg ccgtctggtg cgggcagtaa atccgaccaa gtcgcagcaa gcatcttaaa
    15721 acaatatggt atggctggtc tcaaccaaac tgccaaactc cactttgcca atacgcaaaa
    15781 agcacaaaaa ttattgaaat gaggaaaaaa tatgggagca atccaaaaaa caaaacgctc
    15841 accactagtc gccttcttag ctgaatgggg catcttttta ctgtttatgg cagctttttt
    15901 tgccagtcgt tactttatct ggaatcctgt atctgtcgat ggccattcca tggacccaac
    15961 gcttcaacac caagaaaaac tcatcatgct caaaacatcc tctatcgacc gctttgatat
    16021 tgttgtagcc agcgaaacag acagcgatgg caaggaaaaa ctgattgtca aacgtgtgat
    16081 tggtatgcca ggtgacacca ttcgctacga aaacgatgtc ctctatgtta acgaccaaaa
    16141 agtggacgag ccttacttag atgaatatct agctgcattc caaaaagata aacttcaaga
    16201 agtctattct tataacaaac aattccaagc tgtggcccaa tctgctgaag ctttcacaca
    16261 agatgccaat ggttacgtag actttaccgt gacagtccca gaaggacaat actacctgat
    16321 gggagatgac cgccttgtct cactagatag tcgtagtgta ggaacatttt cccgtgaaaa
    16381 catcaaagga gaagttgtct ttcgcatgtg gcctctcaac cgtattggga ctgttgatta
    16441 atacaaacaa gtttggagca aaaagcacag caccacttct cagagttcgt gtcaacatcc
    16501 cagcgcagtg gttgattggg tttaacagtc cactggactg ttggagctgt gcgggttggg
    16561 agtaaaatag tccagtggac tattttagcc cgaacctgca tatttggaag tgaggggaac
    16621 tctttttggt ctatgcgagt tcttccccac tcccttttca ttattattgg aaataaactc
    16681 tatgaacgaa gtgtatttta ccggtactat tgaccggatt atttttgaaa atcctagtaa
    16741 tttttataaa atccttctcc ttgaaatcga ggagacagac gcagactatg atgactacga
    16801 aattattgtg accggaacga ttgccgatgt cattgaagga gaagactatc gtttctatgg
    16861 caatctggtc acccatccca agtatggtca gcagctgcaa atttcgcgtt acgaacgcag
    16921 caagcctacc tcagctggtc tggtcaagta tttctccagc gagcatttca agggaattgg
    16981 acgcaaaaca gctgaaaaaa tcgttgagct ctatggcgaa gataccattg ataagatttt
    17041 agctgaacct gaaaaactaa cccaaatcac aggcctatcc agcaagaaca tgcaggcatt
    17101 tgtcgaaaaa ctccgcctca attatggaac cgagttgatc ttggcaaaac tagccgagta
    17161 tggcattccc aataaattgg cctttcaaat ccaagaccag tataaggaaa aaacacttca
    17221 gattattgaa gaaaatccct atcaactggt cgaagatgtc caggggctcg gctttaccat
    17281 tgccgatagg attgcggaaa atctaggaat tgccagtgat tcaccccaac gttttcgggc
    17341 tggcatgctc tttagtctca ttcatcgctc catggaaaca ggcgatacct atgtggaggc
    17401 cagagacttg ctggaagcaa cccttgaact gctggaaaaa tcccgccata cagagctgga
    17461 ccccgctgct gttgccaaag aattgacggg actgattgca gacgacaagg tacagcaaga
    17521 aggcacaaag atttttgaca acagcctcta ctttgccgaa catggtatcc atacaaacct
    17581 aactcgcctg atgggaaaaa acggcttcaa gcccttccca cgcgcagacg tcgaggctgc
    17641 catagcagag ctggaaagca tatcttctct cacctacgat aacattcaaa aagaagccat
    17701 tgtccaagcc attaccaatc cgcttttcat tctgacaggc gggccaggga ctggaaaaac
    17761 aacggttatc aacggcatta tcgcagtcta tgctatcttg cataagattg acctgacgcg
    17821 aaaccgagaa gaatgcccag tcctcctagc cgctccaact ggacgagcaa ccagacggat
    17881 gaatgaattg acagggctgc cttccgccac catccaccgc catctcggtc tggtagaagg
    17941 acaggaggaa tcctaccgtg atgattattt ggatgccgac tttatcatcg tggatgagtt
    18001 ttctatggta gatacttggt tggcaaacca gctcttccag aatatctcct cccagaccca
    18061 agttctgatt gtcggcgatg ccgagcaatt gccttctgtc agccccggtc aagtacttgc
    18121 tgacctcttg aaaattgaca agctgcccag cattactcta gaacgtatct atcgtcaatc
    18181 cgatgattcg accattgtta ccctagccag ccagattcga cagggtgctc tgcctagcga
    18241 ttttcgtgag aaaaaggctg accgttccta ttttgaagcc cagaatgaac aaattccagc
    18301 cctgattgag cgcattgtcg gcgcagccat caagtcaggt attcctgcaa acgaggtaca
    18361 gatcctcgct cccatgtacc gtggggccgc aggcatcgac caactcaaca ctatgaccca
    18421 ggccctgctc aatccactgg aagagggaga gttagaattc ctgcataacg agcaagcctt
    18481 ccgccaaggc gaccgggtca ttcatttagt caacgatgcc gaggccaatg tcttcaatgg
    18541 tgatttaggc tacatcaccg acctccttcc tgccaagtac accgactcca agcaggacga
    18601 aattaccatc aacttcgacg gtagcgaggt cacctatccc cgaaacgaat ggtacaagat
    18661 taccctggcc tatgccatgt ccatccacaa gtcccaaggc agcgagtttc aggtagtcat
    18721 cctccccatc acccgcacca gccaccgtat gctccagcgc aatctggtct acaccgccat
    18781 cacccgctcc aagagcaagc tcatcctcct gggcgaaatc tccgccttcg actacgccgt
    18841 caaaaacgcc ggcaccgtcc gaaaaaccta tctggtccca cgtttccaag gggaaatggc
    18901 agagcaggaa agcaaggaaa gcctgattaa aaaagacgaa agcaaaacag ctacaaccac
    18961 gcaaacccag ccccctactc agccagacag aaaagaacag gttaaagtag tcaaagaaaa
    19021 caaccaacaa ctctcccttc ttgatcaaga ccagccagaa aaaacaagtc cccaacccac
    19081 agaatacatt ttgactgtag acaacctact aaccatcgac cccatgattg gcatagaaca
    19141 ggcagatatt gaagaatttt ttaaagcata aaaaccagca agtcagtaga tgaacaccgt
    19201 tatattcttt tatttgacag cctctaaagc tgctttataa tctgggtgtt cgttgacatt
    19261 gtctaggtat tctacgtaga cgatctcatt gtcggcatta aggacaaaga ccgcacgcgc
    19321 cagcaaattc cactcccgca tgagcacacc gtaggatttt ccaaaggcat ggtcatagta
    19381 atcagacagg gtgatgccat cccctaccat ggcgactgtc ttgccctgtt cttgtaagaa
    19441 cttgacttgg ttggccttgt catctggcag gacctgactg accacctgct caatgccgac
    19501 ttccttggca atagcctggg cagttttttc attatctcct gtcagcatga caacctctag
    19561 ttccatggtt tgcagagcct ggacagcctg acggctggtc tcttttactt tatcagcaat
    19621 ggcaatgact gctagtaatt cttgctggct ggctaggaaa acaggcgtct tagcttgatg
    19681 ggcaaatgtt tccgcaactg cacgtccttt ggaaacatca attccctgtt cccgcatcaa
    19741 ccgttcattt cccagataga tggtctgctc tgctattgtt accgaaagac cacgaccaga
    19801 aagtgcctga aaatcttggc tggcaagtaa gggaattgat tcctcttctg ctgaacgtaa
    19861 gagggcttga gccaatggat gctcggagta ttgttcactg cttgctgcca gttggagaac
    19921 ttgctcacga tttttagtag acaaaaggtg gatgtctgtc acttgtggct tgccctcagt
    19981 aatggtccca gtcttgtcga agacaatggt gttcacacct tgtagggttt taatagtttg
    20041 accagacttg aacaaaagac cattttctgc cccttttcca gtcccaacca tgatagcggt
    20101 tggtgtggca aggcccaaga cacacgggca ggcaatgaca aggacggaga tggtaatgga
    20161 aagtgagaac atctagggct cttgtcccaa gaagtaccaa gcaaggccag aaaggacggc
    20221 taatcccatt acaattggaa caaagactgc tgaaacgcgg tcagccaact gcgcaatcgg
    20281 agcttttgac ccctgtgctt cttccaccaa acgaataatt tgggacaatg tggtatctgc
    20341 tccaactttt gtcgcttcca tttggaaagc accatgttga ttgagagtcg caccaacgac
    20401 tgtatccccg atgttttttt aacaggcaaa ctttcccctg tcagcatgga ttcatcaatt
    20461 gtcgattggc cttctactat tatcccatca actggaatct gttcaccagg gcggacttga
    20521 aggacatctc ctactttgac ttggtctaag gggagggtca cttcttgacc ttcacagaga
    20581 acgcgtgcag ttttaggggc gagattcatc agtttactga tggcttctga agtacgctct
    20641 tttgataatg cctccatgta ttttccaaga gtgataaggg ttaaaataac agctgccgat
    20701 tcaaaataga gctcaggatg tccatgttgg gtggctactt ggttggtagc aatcaaaatc
    20761 gtcataatga tcccttgaaa caaggcagca cttgtcccaa cggcaatcaa actatccata
    20821 ttgggatgac cggcaaacag ggttttaaac cctttttgat aaaatgcacg accaacatat
    20881 aggactggta atacaagaat gagctgaact agggcaaaaa ctagcggctg gtgtaagata
    20941 gctggcaatg gcaatccccc acctggtaac ataggtccca ttgcaatgta gagtagtgga
    21001 agcgtgaaaa tggttgacca gataaatctg cgccataaat catttttgtg ttgttctttt
    21061 ccgcttggtt gagcttctga ctcttgtgtt tttggcagta ccgctttata acctgctttt
    21121 tcaacagctg tcgatatctg ataagctcag atgggctgga tcatactgaa tgtttgtttt
    21181 ttccgttgct agattcacac tggcgttttg tattccatct agcttattca aggctttctc
    21241 gactgtcaga gcacaggttg cgcaagtcat cccattgaca ttatagatgg atgttttcat
    21301 aatactgctc tccttttgac tacatttgca gtcaaatcac atgctttttg attacatttg
    21361 taaacgattt tgattaaaaa aatgagagaa tcctctctca ttaggtatct gatcaaaagg
    21421 gtaacagact tatatatgtt tcatatgtgt ttgaacatcc gttaatttgc taacgattca
    21481 tttagataga tagaacaatt tgtatggatt tgcattagag ttgatggaaa tccagtatct
    21541 ggcttagaac aaactgtttt acgtatgacc gcatgatgcc aatcacgaaa aacagcaagt
    21601 cgaatttttt tcgcttgaaa aatctcgctc attcctattg ttacacaata attaggcact
    21661 tcttctacag ccccttttaa ttccgtcaaa caattcataa cctttgtttc gacagagata
    21721 ggtaacactc gcgactctaa ttttaaaaat tcttgaactg ttaatgttga atccggttca
    21781 ttaaatgcaa tgtgcccatt taggccaatt ccaccaatac ataagtcgat tttacctaac
    21841 tctttgattt tatttgaaat caagtcaata tcaagaggat ctggaaaaat tctttgttct
    21901 tcaggcataa taagagttgg atgtatttga ctgtagacag ttttctgcat aaatcctcga
    21961 aaactaagag ggtggactac gtctatccaa tgtaaatctt ccgataaata ttcatccatg
    22021 tttataaacc aaacatcaga caaatcaatc ttaaattgat tcactaatct aacaaaatgg
    22081 ggataatgac caactggtcc aacaggacaa attatgacag ttttctcatt ttttttgtta
    22141 ttttctttta ttaattctac catttctaga gcaagtgaaa taaaaatttc ctcattattc
    22201 ttttttataa tcaatggaat tctactatgg ttttctaatt cacttttact aaaattgtaa
    22261 tattctatca tgcattacct catgtttcct tgaaaactat gaatgattat tgattcaatg
    22321 taacttttat tgaaaataaa atggctaatt gtgtttcaca agaattattt aatctccatt
    22381 aatatactat tcatttgatc
//
LOCUS       DBNFCO010000029        22305 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.029, whole genome shotgun sequence.
ACCESSION   DBNFCO010000029 DBNFCO010000000
VERSION     DBNFCO010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 22305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22305
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.029"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            43..648
                     /locus_tag="AC1PIV_000941"
     CDS             43..648
                     /locus_tag="AC1PIV_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HIP6611974.1"
                     /translation="MLGWLDRLFTLLFFLMKLSAIYLVLLLLGGVVLGISPANGTIVY
                     LYDNYHMDASKYNFREAFGYFKEHFIRLNLGLGLVFLLIGLLFSGIWLLIQLPQTWWM
                     PAVLITNAFGLFYIFALYALFLKLQVHFEFSLKTGLQLAAVSLFLDWKALVKFLLGSL
                     VCGVLLFKLPLILFFFLPVLWLLFLYDAFDPVYKKVDKDYL"
     gene            645..2294
                     /locus_tag="AC1PIV_000942"
     CDS             645..2294
                     /locus_tag="AC1PIV_000942"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIP6611975.1"
                     /translation="MKKVLIHTLLKSYSLLVIGIVIFFASILSYISWYQYDTNRIRIQ
                     QEVADGLKEELDYYQGRVGNYLADYITDRDRLDSLYHYFQLSPSQYQVWLLSHPHLMV
                     KRISLQDSVRTLYLYYPFVEGVDIAPMDANTVFVSTSDLKSGKKVTAENYKAPQHSIS
                     MTLFSPSTTEGIATIYVTIDADLLEQYIQRKTDLPMTVRVQDSLDREFYSLRPDVASP
                     PLSYRMSGDLQIAVGVDQQYAIEKVGSLVGIIFLGSSCLVALLLLVLRRVFKRYEVQV
                     LDIVDTMQQIRGEDRHLRLQTDNKEQEMYLISSEINQMLDAMDQSIQDIYRLQLAQKD
                     ANMRALQAQINPHFLYNTLEFFRMYAVSKQMDELGDMIYEFSSLLRSSVTQAKMTTVA
                     EELSFCEKHSYICQIRYPRSIAYAYQMDPGCERVEIPRFVIQPLVENYFVHGVDLKRK
                     DNALSVKALKHGQDMEILIRDNGKGMNAETLEAYKHLLASRELSQENRSQSIGLRNVH
                     ERLLLYFGDRYQIELDSKEGEGVTYSILFEGVFPRGDEHDA"
     gene            2284..3576
                     /locus_tag="AC1PIV_000943"
     CDS             2284..3576
                     /locus_tag="AC1PIV_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HIP6611976.1"
                     /translation="MMHKMLVVDDEYMILEGMKHLLPYHEYNVEIVYTAENAEEALDY
                     FSQHTVDLVLTDVSMPDMTGLEMVRRMKEQSSDTHIIIMSGFQEFEYARKAISLGAMD
                     YLLKPINKQELAKLLQQLPTLKKETDREYTKGFLAGTLTASEFLSHSQKTWFAARETP
                     NPMGYCREKNILHQVYYFQLTESRPEGSLYTEEVTPTMTIRQLIDKVERRLFYKQLSE
                     DLTATTTELYKDMEPLLRAGRLAKIVDVLPHLADKLRETTPAVYLTKQFFNQMMSDVF
                     YYFNEEDHQRLEDFYVKVEASRDLHQLMEYFCHYLKKISESSTYSPHIQEVVTIVRER
                     FAEELSLKDMSAHLYLNTVYLGQLIKKETGHTFAELLNHQRIKVAQQLLLNSQLGIEE
                     ICFQVGYTNVGYFYKIFKRICGESPKNYRQKIGQLQTE"
     gene            3589..4449
                     /locus_tag="AC1PIV_000944"
     CDS             3589..4449
                     /locus_tag="AC1PIV_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIP6611977.1"
                     /translation="MSKREELQHLFPKGRLVFEKTENGASIQLPLANQTWFSVDRKDL
                     TDREIELIDLLMNDSSAEQGHPWGRYFQGGGPLPQTLEKLQVIHAHVGHVSDEDGKVA
                     WLDMMAKLLPNLQGYYTGNGQDYLFILHQAPLFDVKEILRDTLATMEFDFGLRITLFL
                     GQIWPAKLVHSWPQLIEAEQSLFHHWRSSHHQSRLLTFGQLYLWAGQLHPVLREGLAS
                     LIAHQQLEKEIVALWQEGAVITKAAQSLYIHRNTLQYRLDKWFDWTGLQLKELTDLAV
                     CYMVIMDLSI"
     gene            4685..5815
                     /locus_tag="AC1PIV_000945"
     CDS             4685..5815
                     /locus_tag="AC1PIV_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIP6611978.1"
                     /translation="MVQLNLKNIYKKYPNSEHYSVEDFNLDIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGEAYIDGVLMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYSKDEIKKRVEEAAQILGLTEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRTEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRIEQIGSPEELYNRPVNKFVASFIGSPAMNFFTVTLQDGVLVGDGFKVELPEGR
                     RKHLEEKGYNGKSFTLGIRPEDIKASQLELDTYPSSIVEAEVVVSELLGAETMLYSKV
                     GSTEFVSRVDARDYHNPGDKVRLTFNLNKAHFFDDETSKAIV"
     gene            6103..6321
                     /locus_tag="AC1PIV_000946"
     CDS             6103..6321
                     /locus_tag="AC1PIV_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611979.1"
                     /translation="MKTLLKKIRLAALSILLYNLILILSIWLGKVSSKEEFMIAVAGN
                     AVMMGLSFVHLHNQVSDEFHGKVEEPSA"
     gene            complement(6318..7286)
                     /locus_tag="AC1PIV_000947"
     CDS             complement(6318..7286)
                     /locus_tag="AC1PIV_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HIP6611980.1"
                     /translation="MSLSLRTIKLIFATVLAIYLATVLGLSYTTAAGIIAILSVLDTR
                     KSSFKMARNRLFSTLLALTIAVLTFALFGFGIWTLGIYLALYVPLAYRFNWEAGIAPS
                     TVLVTHLLLEQDISLIFLGNELTLFLIGAGLALLFNLYMPSQEKKIQAYHDQVEDLLK
                     QILLRFEAFLLNGDGRNEAELITQLDKTLDEALKVVYLDRHNQLFQQTNYQVHYFEMR
                     AAQNKILRTMAGNINKCLLEGRENVILSSLFERAAQQLSRDNSAKELLLDIELFHATF
                     RERPLPQTREEFETRATLFQLLHDMEAFIRLKVDFYEVYKDQEPSI"
     gene            complement(7361..7750)
                     /locus_tag="AC1PIV_000948"
     CDS             complement(7361..7750)
                     /locus_tag="AC1PIV_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1761 domain-containing protein"
                     /protein_id="HIP6611981.1"
                     /translation="MTLIFGIVAGLIAFAIGGLWYGLIFRDAWIKASGIDMAKVEADR
                     QAGKNGQKEMVISLVIEVLTAVVVIFFIKTLGVSPLHAAGGMGVIAVLASLKNYVFEQ
                     RPINLILINESYKLVCYLVVGILALFA"
     gene            7945..9162
                     /locus_tag="AC1PIV_000949"
     CDS             7945..9162
                     /locus_tag="AC1PIV_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PASTA domain-containing protein"
                     /protein_id="HIP6611982.1"
                     /translation="MDQWMRDFEERQRHDELKQKMDAQTSAMNSQAIALQKQNNILQK
                     EHERQIEKEFKDRIFQLRLHLAQVTDESQRFVIQQMLSEAEEDYENYQREQAEKRLAD
                     AKRRKIWLIISSVVAVLGMAGLYFVYQDISQVTVPELYGIELSEAKDLLYEEGLKVGT
                     ITEVGGQSVQPGMVSVSSPSSGKKVKRGSAVNLIIAKNVDAKDTTVVEDSSTSEVATS
                     KTAGSSQASSQSQVGSAVQLFTVDIKKQGLVIRQEPSLSGEVVTNIEPGTYTIVETTQ
                     KEGHSWGRLKSGQGWISLTDLHNPVPQVDTKNLTTDQVKAWVMDDLFSRSVMIEKYRK
                     DQVVISVRMAEDGLVYADVTVPSDPNFEPRNWSYRINSRGELEASEYDTDPEQGGVNW
                     YVAQHYYLENSVN"
     gene            9218..9946
                     /gene="rlmB"
                     /locus_tag="AC1PIV_000950"
     CDS             9218..9946
                     /gene="rlmB"
                     /locus_tag="AC1PIV_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HIP6611983.1"
                     /translation="MEQNDIVYGVHAVVESLEANTGNKLYIQDDLRGKNVEKIKALAA
                     EKKVSISWTPKKTLSDMTEGAVHQGFVLRVSEFAYADLSVILEKAEQEDNPLILILDG
                     LTDPHNFGSILRTADATQVAGIIIPKHRAVGVTPVVAKTSTGAVAHVPIARVTNLSQT
                     LDKLKEAGFWVFGTDMNGTPSHKWNTAGKLALIIGNEGKGISSNIKKQVDEMITIPMK
                     GHVQSLNASVAAAVLMYEVFRKKI"
     gene            9947..10468
                     /locus_tag="AC1PIV_000951"
     CDS             9947..10468
                     /locus_tag="AC1PIV_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HIP6611984.1"
                     /translation="MKEKVLIVDGYNMIAFWQATKQDFKKGDLDAARTTLLRTLSHYA
                     AFEQIEVICVFDAHHVPGLRQQYDEFKVSVIFTEEEETADSYIERLSAQLNSDRRKQV
                     SVATSDLNEQWVVFSQGALRVSARELEERTKVIKKDLDKFVDQVELYTPRLNPWSDGN
                     FQALKEMMEEMKE"
     gene            10465..11328
                     /locus_tag="AC1PIV_000952"
     CDS             10465..11328
                     /locus_tag="AC1PIV_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HIP6611985.1"
                     /translation="MTFTIVTDSTSDLPISWVQENDVTVLGLTINLDGATYETVGENR
                     LTSADLLEKMASGSQPTTSQVNVGQFEEVFEAAAKEDHEVLYLAFSAALSGTYQSAVI
                     ARDMVMDQYPEAVITIVDTKAATIGEGYLVMKAVEARAAGKTLAETKAIVEDLVPRLR
                     TYLLVDDLNHLVRGGRLSKAAALIGGLVNIKPLLALNAEGKLEAIAKIRGRKKGIKEM
                     LNLTLDNLDHSTVMVAYTGDIEAAEGVKSSLLEDDRISDVLLTELGPVIATHTGTGVL
                     AILSIGTAMRA"
     gene            11793..12239
                     /gene="rplM"
                     /locus_tag="AC1PIV_000953"
     CDS             11793..12239
                     /gene="rplM"
                     /locus_tag="AC1PIV_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HIP6611986.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKSISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            12259..12651
                     /gene="rpsI"
                     /locus_tag="AC1PIV_000954"
     CDS             12259..12651
                     /gene="rpsI"
                     /locus_tag="AC1PIV_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HIP6611987.1"
                     /translation="MAQAQYTGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTQGSYDVFVNVNGGGYGGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            12964..13417
                     /locus_tag="AC1PIV_000955"
                     /pseudo
     CDS             12964..13417
                     /locus_tag="AC1PIV_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647366.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
     gene            13508..13849
                     /locus_tag="AC1PIV_000956"
     CDS             13508..13849
                     /locus_tag="AC1PIV_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HIP6611988.1"
                     /translation="MREDIQINERALILSDQLVEVLESIHDPEIELDIYNLGLVYEIH
                     LDETGFCKVVMTFTDAGCSCADTMPGELVAALKTIDGIEDAQVEIVWSPAWKMTRISR
                     LGRITLGISPK"
     gene            complement(13868..14263)
                     /locus_tag="AC1PIV_000957"
     CDS             complement(13868..14263)
                     /locus_tag="AC1PIV_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6176 family protein"
                     /protein_id="HIP6611989.1"
                     /translation="MKLNVELSRFRVKEGKTVQVDEWMAFLNEHMEDTLLTLEGEKMY
                     VETIFREVLDGREYLYWYSVQAEGGIEVEDSESYIDKKHLEYWEECIDPSYGMVDLDP
                     QVLMIPKPIYETMEELDRQYDDTFKKELQ"
     gene            complement(14314..16029)
                     /gene="ilvD"
                     /locus_tag="AC1PIV_000958"
     CDS             complement(14314..16029)
                     /gene="ilvD"
                     /locus_tag="AC1PIV_000958"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004160 - dihydroxy-acid dehydratase
                     activity [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HIP6611990.1"
                     /translation="MTDTNKLKDFRHRSSVYDSMVKSPNRAMLRATGMTDDSFEKPIV
                     GVISTWAENTPCNIHLHDFGKLAKEGVKEAGAWPVQYGTITVADGIAMGTPGMRFSLT
                     SRDIIADSIEAAMGGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAVFAYGGTIAPGNL
                     NGKDIDLVSVFEGIGKWNNGDLTAEEVRQIECNACPGPGGCGGMYTANTMATAIEVMG
                     MSIPGSSSHPAESPEKKADIEEAGRAVVRMLELGIKPSDIMTREAFEDAITVTMALGG
                     STNATLHLLAIAHAANVDLTLEDFNDFQERVPHLADLKPSGKYVFQDLYNVGGVPAVM
                     KYLLKNGFLHGDRITCTGKTVAENLKNFADLTPGQDVIMPLENPKRADGPLIILKGNL
                     APEGAVAKVSGVKVRNHTGPAKVFDSEEEAIEAVLTDEIVDGDVVVVRYVGPKGGPGM
                     PEMLSLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDLV
                     TVDQDTKEITMHVSDQEIEERKKTTVIPPLYSRGVLGKYAHTVSSASKGAVTDFWRPE
                     RTGKK"
     gene            complement(16190..16606)
                     /locus_tag="AC1PIV_000959"
     CDS             complement(16190..16606)
                     /locus_tag="AC1PIV_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611991.1"
                     /translation="MTLSTSVTNSTTRVSRTFISYLAITAFLFIFSRIYESLSYGEVS
                     VFMHYMFCVPLIGGAVLLGLLQLIPTLSRLSYNLWNSGVATITAGCLLRGIINLSGRS
                     TTLDQPYWYIGAAFLVLSLVGLFINPSANNHRKTTS"
     gene            complement(16581..17519)
                     /locus_tag="AC1PIV_000960"
     CDS             complement(16581..17519)
                     /locus_tag="AC1PIV_000960"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiester glycosidase family protein"
                     /protein_id="HIP6611992.1"
                     /translation="MKLLKKPFAYASIFGMLLTGGFTYSMLKTFVLSEAITTVAASNA
                     TSTSEQNTTTASSSTTATTATNVSTTDTSYTDDNIQINLETITTNNTTVYVADIQVSS
                     PEYLKTALAQNTYGTNVTAKTSETAAANNAILAVNGDYYGANSTGYVIKNGVLYRDTV
                     RDNAAYGDLAIYADGSFEVIYENEITAQELIDKGVVNLLAFDPSLVENGEIVVDTSTE
                     VGRAMSSNPRSAIGIIDENHYIIVVADGRTSESQGLSLYQLAEVMKQYGAQTAYNLDG
                     GGSSTLYFNGQVINNPTTNGNTISERAVSDIVYIGY"
     gene            complement(17506..18558)
                     /locus_tag="AC1PIV_000961"
     CDS             complement(17506..18558)
                     /locus_tag="AC1PIV_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014917313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HIP6611993.1"
                     /translation="MYYVVIPAYQPDEKLIQLLKIMKNRLNCQVIVVDDGSTGASKNI
                     LEIAKTYAIVLHHDVNKGKGQALRTAFSFIQDLRKPGVAVTADSDGQHAVNDIDRVAR
                     AAMNLPSRLILGVRQFTKDIPLRSRFGNKLTRVLFRLQTGVNVSDTQTGLRGFHTDLI
                     PFMLDIEGDHYEYKMNMLTQASQRYKITEVPIQTIYIDDNASSHFRPIKDGLLIYKNL
                     FKFALASFGGFLVDYGIYALALLLLTSLPTALRLLVANTIARICSATCNFALNKKLVF
                     NNEESIARTGVGYFTLALVLFLCDTALLYLFHQILGLNLYIVKLAVGIFLFLASWFIQ
                     KNIIFKERKSFSHEIA"
     gene            18783..20486
                     /locus_tag="AC1PIV_000962"
     CDS             18783..20486
                     /locus_tag="AC1PIV_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HIP6611994.1"
                     /translation="MQEIQLDQPRSGSYLILDTLHQLGVDLVFGYPGGAVLPLYDAIY
                     QYEGIQHILARHEQGAVHEAEGYAKSSGKVGVAIVTSGPGATNAITGIADAMGDSVPL
                     LVFTGQVATRGIGKDAFQEADVLGMTMPITKYNYQIRDTADIPRVITEALHIATTGRP
                     GPVVIDVPKDIQERVVDFYHDPTLHLPSYQPTIEPNGLQVKKILKQLSQAQKPVILAG
                     GGVNYADANKELVAFAERYRIPVVSTLLGLGAMPIEHELSLAMGGMHGSYAANMAMDQ
                     ADYIINIGARFDDRLTGNPTTYAPNATVAHIDIDPAEIGKVVKTAIPVVGDAKATLKA
                     LLALETVETGYADWTAQVLENKRRAPFWYDEDEKVIKPQAAIELIGQLTQGDAIVVTD
                     VGQHQMWAAQFYPYRHARQLVTSGGMGTMGFGIPAAIGAKLANPDKEVIIFVGDGGFQ
                     MTNQELAILNGYGVPIKVVLINNHSLGMVRQWQESFYEKRRSQSVFDDEPNFQLLAEA
                     YGISHYSFDNPATLSEDMKVILEDKPMLIEVHISNREHVQPMVPAGKSNAEMLGVKFN
                     A"
     gene            20479..20955
                     /gene="ilvN"
                     /locus_tag="AC1PIV_000963"
     CDS             20479..20955
                     /gene="ilvN"
                     /locus_tag="AC1PIV_000963"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1990610 - acetolactate synthase regulator
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HIP6611995.1"
                     /translation="MRRMLTAKLRNSSGVLNRFTGVLSRRQINIESISVGPTEVDGIS
                     RVTVIVDVVSHDEVEQIIKQLNRLIDVVRVRDLTDIPHLEREVILVKISAPPTKRAEI
                     LAIIQPFRANVVDVAPHSITIQMTGDGDKIDALLRVIQPYGIKNIARTGATGFSRD"
     gene            21096..22118
                     /gene="ilvC"
                     /locus_tag="AC1PIV_000964"
     CDS             21096..22118
                     /gene="ilvC"
                     /locus_tag="AC1PIV_000964"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HIP6611996.1"
                     /translation="MTVTMQYEKDVTVAALDGKRIAVIGYGSQGHAHAQNLRDTGHDV
                     IIGVRAGKSFDKAKEDGFETFEVAEAAKQADVIMILAPDEIQADLYNEEIAPNLEAGN
                     ALGFAHGFNVHFEFIKVPADVDVFMCAPKGPGHLVRRTFEEGFGVPALYAVYQDATGN
                     AKHIAMDWAKGVGSARVGLLETTFKEETEEDLFGEQAVLCGGLTALMQAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLVYEGGFKKMRQSISNTAEFGDYVSGPRVITDQVKENMK
                     AVLADIQSGKFANDFVNDYKAGRPRMEAYRKEAENLEIEKVGAELRKAMPFVGRNDDD
                     AFKIYN"
     gene            complement(22115..>22305)
                     /locus_tag="AC1PIV_000965"
     CDS             complement(22115..>22305)
                     /locus_tag="AC1PIV_000965"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6611997.1"
                     /translation="FYFFNVFMNEMGKRAGKNQLFYSFSEIGKKGNDIPSSANSNLKC
                     IAITQSKADYPPIHHDSV"
BASE COUNT         6504 a         4446 c         5145 g         6210 t
ORIGIN      
        1 accgattttt tgataaaata gataaaaaag gaggaatata caatgttagg gtggttagac
       61 aggcttttta ctcttctgtt cttcctcatg aaattgagtg ccatctattt ggttcttcta
      121 ttgctaggag gcgtagtgct gggcatttca ccagcaaatg gaacgatagt ttacctctac
      181 gataactatc atatggatgc atctaagtat aattttcgag aggcgtttgg ctattttaaa
      241 gagcatttta ttcggcttaa ccttggcctt ggtcttgtct tcttattgat tggtctttta
      301 tttagcggca tttggctctt gattcaattg ccccagacct ggtggatgcc agcagttctt
      361 attacaaatg cttttgggct tttctatatt tttgcactct atgctctctt tttaaaactt
      421 caagtacatt ttgaatttag tctaaaaaca ggcttacagt tggcggctgt ctcgcttttt
      481 cttgattgga aagccctggt caaatttttg ttaggcagtc tcgtctgtgg ggtcttgcta
      541 ttcaagcttc ccttgatttt attcttcttc ctaccggtcc tatggctctt gtttctctat
      601 gatgcctttg atccagttta taagaaagtt gacaaggatt acttatgaaa aaagttttaa
      661 ttcatactct tttgaaaagt tattctttat tagtgattgg gattgttatt ttctttgcca
      721 gtattctttc ctacatcagc tggtatcagt atgataccaa tcgcatccgc attcaacagg
      781 aagtagcaga tggtctaaaa gaggagttgg attattatca aggacgggtt gggaattatc
      841 tagcagacta cattacggac agggatcgtc tagacagcct ttatcactat tttcaattat
      901 ctccttctca gtaccaggtc tggttactga gtcacccaca cctgatggtc aaacggattt
      961 ccttgcagga ttctgttcgc actctctatc tctattatcc cttcgtagaa ggagtcgata
     1021 ttgctccgat ggatgcaaat actgtctttg tttctacctc tgacttaaag tctggtaaaa
     1081 aggtcacggc cgaaaattac aaggctccgc aacatagtat ttcgatgacc ttattttctc
     1141 catcgacaac agaaggtatt gcgaccatct atgtcaccat cgatgcggat ttgctcgaac
     1201 aatatattca acgtaagacg gatctcccca tgaccgttag agttcaagat tctctggatc
     1261 gggaatttta tagtctgcga ccagatgttg cctcacctcc gctctcctat cgaatgagtg
     1321 gggatttgca aattgcagtt ggagttgacc agcagtatgc tattgaaaaa gttggcagcc
     1381 tagtcggaat catttttcta ggaagtagtt gtctcgttgc tcttttacta ctggtcctga
     1441 gaagggtgtt taaacgatat gaagttcaag tactggacat tgttgatacc atgcaacaga
     1501 ttcgtggcga agacaggcat cttcgtctac agacggacaa taaagagcag gaaatgtatc
     1561 ttatttcatc agaaatcaat cagatgctgg atgctatgga ccagagtatt caagacatct
     1621 atcgcttgca gttagctcag aaagatgcca atatgcgagc cttacaagcc cagattaacc
     1681 cccattttct ctacaatacc ttggaatttt tccgtatgta tgcagtcagc aagcagatgg
     1741 atgagctagg ggatatgatt tatgaatttt caagcttgct tcgcagtagt gtgacacagg
     1801 caaaaatgac aacggtggca gaagaacttt cattttgcga aaaacatagc tacatttgtc
     1861 aaatccgcta tccccgttcc attgcctatg cctatcaaat ggatcctggg tgcgaaaggg
     1921 ttgaaattcc tcgttttgta atccagcctc tggtagaaaa ttattttgtc catggagtag
     1981 acctcaaacg aaaagacaat gcgcttagtg tcaaagctct caagcatgga caggatatgg
     2041 aaattctcat cagagataat ggtaagggaa tgaacgcaga aactctggaa gcctacaaac
     2101 acctcttggc aagtcgagaa ctgtcgcaag aaaatcggtc acaatcaatc ggattacgaa
     2161 acgttcacga gcggttactt ctctattttg gagaccgtta ccagatagaa ttagattcta
     2221 aagaagggga aggggtgaca tattcaatct tatttgaagg tgtcttcccc cgaggagatg
     2281 agcatgatgc ataagatgtt agtagttgat gacgaatata tgattttgga agggatgaag
     2341 catcttctcc cttatcatga atacaatgtc gagattgttt atacggcaga gaatgccgaa
     2401 gaagcgctgg attatttttc acagcatact gtggaccttg tcctaaccga tgtcagcatg
     2461 ccagatatga caggcctaga aatggttcga cgaatgaaag aacaatcgtc tgatacccat
     2521 attatcatca tgtctggttt tcaagaattc gaatatgccc gtaaagctat ctccctaggg
     2581 gcaatggatt atctccttaa gcccatcaat aaacaagaac tggctaagct gctccaacag
     2641 ctaccaacct tgaagaaaga gacagatagg gaatacacca agggcttctt ggcaggaacc
     2701 ctgacagcga gtgagttctt aagtcactcc cagaaaacat ggtttgccgc tagagagact
     2761 ccaaacccaa tgggctactg tcgtgaaaaa aatattttac atcaagtcta ctattttcag
     2821 ttgacagaaa gtcgaccaga gggtagtcta tatacagaag aagttacccc gacgatgacc
     2881 atacggcagt tgattgacaa ggtagagagg cgcttatttt ataagcaact atcagaagat
     2941 ctaacggcta ctaccactga actctataaa gatatggaac cgcttctacg tgcaggaaga
     3001 ttggcaaaaa tcgttgatgt tttaccacat ttggctgata aattacggga aaccactccg
     3061 gcagtctacc taacaaaaca attttttaat cagatgatgt cggatgtgtt ttactatttt
     3121 aatgaagaag accatcagcg cttggaagat ttctatgtaa aggtagaagc gagtcgagat
     3181 ttacatcaac taatggagta tttttgtcat tatctgaaaa aaatttccga gagttccact
     3241 tacagtccac atatacagga agtcgttacg attgttcgtg aacgctttgc agaggaactg
     3301 tctttgaaag atatgagtgc tcatctctac ctaaatacgg tttacctagg tcaacttatc
     3361 aaaaaagaga ccgggcatac ttttgcagaa ttgctcaatc atcagcgaat caaggtagcg
     3421 caacagcttc tcttgaacag tcagttggga atcgaagaaa tttgttttca agttggatat
     3481 acaaatgtcg gttacttcta taagattttt aaacgcattt gtggggaatc tcccaaaaat
     3541 taccgacaga aaatcggtca attacagaca gaatgagatg gaggcgagat gagcaaaagg
     3601 gaagaattgc agcacctatt tccaaaagga aggcttgtat ttgaaaagac agaaaacgga
     3661 gcaagtatcc agttgcctct ggctaatcaa acctggtttt ccgtcgatcg caaggatttg
     3721 acagatcgag aaatcgaact gattgacttg ctgatgaatg actcgagcgc agaacaaggt
     3781 catccttggg gacgctattt ccaaggggga ggtcctcttc cacaaacctt ggaaaaacta
     3841 caggttattc atgctcatgt aggccacgta tccgatgaag atggaaaggt agcctggctt
     3901 gatatgatgg ccaaactcct ccccaatctc caaggctact atacaggcaa tggacaagat
     3961 tacctgttca ttctacatca ggcacctctt tttgacgtca aagaaatact gcgtgacacc
     4021 cttgctacca tggagttcga ttttggtctg agaattacat tgtttttagg gcaaatctgg
     4081 ccagccaaat tggtacactc ttggccgcaa ttaatcgaag ctgaacaatc cctttttcac
     4141 cattggcgaa gcagccacca tcaatcacgg ttgcttacct tcggtcagct ctatctttgg
     4201 gcaggtcaac tccaccccgt tttgagagaa ggacttgcta gtttgattgc ccaccagcag
     4261 ctagaaaagg aaattgtagc tctttggcaa gaaggtgcgg tcataaccaa ggcagcccag
     4321 tctctctata tccatcgaaa tacgctacag tatcgcttgg acaaatggtt tgattggacg
     4381 ggattacagc tcaaggaatt gacggatttg gcagtttgct acatggttat catggattta
     4441 agtatctaat aggagctaat gatgagaaaa gcgttgtagc ctttgagaat gccacccatc
     4501 gcttcgtccc ttttctactg aaaatcccaa agggctcatt gaatttttgg aaagtaaact
     4561 atttcagtaa cacagtcttt tgtgcaactt gtacaaaaga ttgtgttctt tttgttcacc
     4621 ttgacctaga aaaataaagc gttttcattt acaataaaac tatcaaagaa agcgaggatt
     4681 gaacatggtt caattgaatt taaaaaatat ctataaaaaa tatccaaaca gcgagcacta
     4741 ctctgttgaa gactttaact tggacatcaa ggacaaggag tttatcgtat ttgtaggtcc
     4801 ttcaggatgt ggtaaatcaa caactcttcg tatgattgct ggtttggaag atatcacaga
     4861 aggggaagca tacatcgacg gcgttctcat gaatgatgtg gctccaaaag accgcgacat
     4921 tgccatggta ttccagaact atgccctcta cccacacatg actgtatttg acaacatggc
     4981 ctttggtttg aaattgcgta aatacagcaa ggatgaaatc aaaaaacgtg tagaagaagc
     5041 tgctcaaatt cttggtttga cagaattctt agaacgtaaa ccagctgacc tttcaggtgg
     5101 acaacgccaa cgtgttgcca tgggtcgtgc catcgttcgt gatgcaaaag tattcttgat
     5161 ggatgaacct ttgtcaaact tggatgcaaa actgcgtgta tccatgcgta cagagattgc
     5221 taaaatccac cgccgtatcg gtgcgacaac catctatgta acccacgacc aaacagaagc
     5281 tatgaccttg gcagaccgta tcgttatcat gtctgcaact aaaaacccag caggcacagg
     5341 tacaatcggt cgtatcgagc aaatcggtag cccagaagag ctctacaacc gccctgttaa
     5401 caagtttgtt gctagcttca tcggtagccc agctatgaac ttcttcacag ttacgcttca
     5461 agatggcgtt cttgttggag atggtttcaa ggtggagctt ccagaaggac gtcgcaaaca
     5521 cttggaagaa aaaggctata atggcaaatc atttaccctc ggtatccgtc cagaagacat
     5581 caaggcttct cagttggaat tggacactta tccatcttcc atcgtagaag cagaagtggt
     5641 tgtatcggag cttctcggtg cagaaaccat gctctactct aaagtaggta gcacagagtt
     5701 tgtatctcgc gttgatgcac gcgactacca caacccagga gacaaagttc gcttgacctt
     5761 caacctcaac aaagctcatt tctttgatga tgaaacaagc aaggcgattg tctaaccttt
     5821 ctaaaatcgt tcataaaaca cctgaccgct agatgaaaat ctggcggttt tttggggtta
     5881 agaacgcata aatacttgtt atttttatta aagaggctgg gcaaaaagcc cagttccact
     5941 tctcagagtt cgtgtcaaca tctcagcgca gtggttgatt ggcagatttg ttcgtgtttt
     6001 acactccaaa tctgacctaa tcaactgtgc gggggtggga aaacgaactc ttctatggat
     6061 ggtcgagttc tgtcccactc ccaacactta caggaggttc ctatgaagac actactgaaa
     6121 aaaattcgtt tggcagctct ttctatcctt ctttacaatc tcattttaat cctctccatt
     6181 tggctaggaa aggtatcttc caaggaagaa tttatgattg cagttgcagg gaatgcagtc
     6241 atgatgggcc tatctttcgt gcatttgcac aaccaagtat cagatgaatt tcatggaaaa
     6301 gtagaagaac cgtcggctta aattgacggt tcttggtctt tatagacttc ataaaaatca
     6361 accttgaggc gaataaaagc ttccatatca tgcaggagtt gaaagagggt agcacgggtt
     6421 tcaaattctt cccttgtttg tggcagaggt cgctcgcgga aggtggcatg gaatagttcg
     6481 atgtctagga gcagttcctt ggcggagttg tctcggctca gttgctgggc tgctcgctcg
     6541 aagaggctgg acaggatgac attttctctg ccttccagta aacacttgtt gatatttcct
     6601 gccatggttc gcaagatttt gttttgtgct gcccgcattt caaagtaatg gacctggtag
     6661 ttggtctgct ggaagagctg gttgtggcgg tctaggtaga cgaccttcag ggcctcatcc
     6721 aaggtcttat ccagctgcgt aatcaattct gcctcgtttc gtccgtcgcc gttgagcaga
     6781 aaggcttcaa agcggaggag aatctgcttg agtaggtctt cgacttggtc atggtaggcc
     6841 tggattttct tttcttgcga gggcatatag aggttgaaca agagtgccag tcctgcccca
     6901 atcagaaaaa gcgtcagctc atttcccaaa aaaatcagcg aaatatcttg ctctagcaag
     6961 agatgggtga cgaggacggt cgatggggcg atgccagcct cccagttgaa acggtaggcc
     7021 agagggacgt agagtgctag gtagatgccc agggtccaga tgccaaagcc aaagagggcg
     7081 aaggtcagga ctgctatggt cagggccagg agggtggaaa agaggcggtt gcgggccatt
     7141 ttgaagctgg acttgcgggt gtcgaggacg ctgagaatgg cgatgatgcc tgccgctgtc
     7201 gtataagaca ggcccagtac ggtcgctagg taaatagcca gaacggtggc aaatatcagt
     7261 ttgatggtgc ggagggagag ggacatgagg gctcctttgg ttttagtcta tttctattgt
     7321 atcataaaat aaaaacctcc taaggatagg agggaattac ttatgcaaat agagctagaa
     7381 taccgactac taggtagcag actagtttgt agctttcgtt gatgaggatg aggttgatag
     7441 gacgttgctc aaagacgtag tttttcaatg aagcaaggac cgcaattacg cccatgccac
     7501 cagctgcatg aagtggtgaa acaccgaggg tcttgatgaa gaaaataacc acaacagcag
     7561 tcagtacttc aatgacaagg gaaatcacca tttccttctg tccatttttg ccagcctgac
     7621 gatctgcttc taccttagcc atgtcaatgc ctgaagcctt gatccaagca tcgcggaaaa
     7681 tcaaaccata ccacaaacca ccaatagcaa aggcaatcag ccccgccaca attccaaaaa
     7741 taagtgtcat aaaatctcct ttttcgattc cgtttgtacg gacaaatagt agatgttaga
     7801 atatcatagg ctttactatt tgtcaaaagt tagattgaaa cggggtgaaa atgaggattg
     7861 acaaattaag gtgttatgct atactaaaat aaaatagatt ttatttgtag ataataacca
     7921 atattttatg aggagatgat tattatggat caatggatgc gagattttga agagcggcag
     7981 agacatgatg aattgaagca aaaaatggat gctcaaacct ctgctatgaa ctctcaagca
     8041 atagcacttc aaaaacaaaa taacattttg caaaaagagc atgagcgtca aattgaaaaa
     8101 gagtttaagg atagaatttt tcaattacga ttgcacttag cacaggttac ggatgagagt
     8161 caacgatttg tcatccagca aatgcttagc gaagctgagg aagattatga gaattatcaa
     8221 agagagcaag ctgagaaacg tttggcagac gcaaaaagac gaaagatatg gctaatcatt
     8281 tcaagtgttg tggctgtgtt aggaatggct ggcttatatt ttgtatacca agatatttct
     8341 caagttacag ttcctgaatt atatggtatt gagctatctg aagctaagga tttactgtat
     8401 gaagaggggt taaaagttgg tacaataaca gaagttggtg gacagtcagt tcagcctggg
     8461 atggttagtg tatcttctcc aagtagtggg aagaaggtaa agcggggaag tgcggttaac
     8521 ttaattattg ctaaaaatgt agatgcaaag gatactaccg tagttgagga tagttcaact
     8581 agtgaggtag ccactagtaa gactgctgga agttcgcaag cttctagcca gtctcaggta
     8641 ggtagcgccg ttcaattgtt tactgtggat attaaaaaac aaggactggt tattcgtcag
     8701 gaacctagtt tatctggaga agttgtgacc aatatagaac ctggaacgta cacgatagtt
     8761 gagacgactc aaaaggaagg acatagttgg ggcagattaa agtcaggaca gggttggatt
     8821 tcgttgacag atttgcataa tcctgtaccg caggttgata ccaaaaactt aacgacagat
     8881 caggtaaaag cttgggttat ggatgattta tttagccgta gcgtcatgat tgaaaagtat
     8941 cgaaaagacc aggttgtcat aagtgttcgt atggctgagg atggtttagt ttatgcagat
     9001 gtaactgtac catcagaccc taattttgag ccacgaaatt ggagttatcg gatcaatagt
     9061 cgtggggagt tggaagctag tgagtatgat acagatccgg aacaaggggg tgtcaactgg
     9121 tatgttgccc aacattatta tctggaaaac agtgtgaact aagaaagctg agaaattctc
     9181 ggctttttcc ttttcaaaaa tatgctataa taaaaccatg gaacagaatg atatcgtata
     9241 tggcgtacat gctgtggtgg agagtttgga ggctaacacc ggcaacaagc tctacatcca
     9301 ggatgatttg cgcggaaaaa atgttgaaaa aatcaaggcc ctggcggcag agaagaaggt
     9361 gtcgatttct tggacgccca agaagaccct gtctgacatg acagaaggtg ccgttcacca
     9421 aggctttgtc ctgcgggtct ctgagttcgc ctatgcggac ctgtcggtga ttctggaaaa
     9481 agcagagcag gaagacaatc ccctcattct catcttggac ggtctgacag acccccacaa
     9541 cttcggctcg attttgcgga ccgcagatgc cactcaggta gctggcatca tcattcccaa
     9601 gcaccgagca gttggcgtga cgcccgttgt ggcaaagacc tcaacaggtg cggtggccca
     9661 tgtcccaatc gcccgagtga ccaatcttag ccaaactctc gataagctca aggaggctgg
     9721 tttctgggta tttggcacgg atatgaacgg aactccaagc cacaagtgga atacagctgg
     9781 caaactagct cttattattg gcaacgaagg caagggcatc tccagcaata tcaaaaagca
     9841 ggtggatgag atgattacca ttcctatgaa gggccatgtc caatctctca acgccagcgt
     9901 agcagcagct gtgctgatgt acgaagtatt tcggaagaaa atctaaatga aagaaaaagt
     9961 tctcattgta gatggctaca acatgattgc cttttggcag gccaccaagc aagattttaa
    10021 aaagggagac ttggatgcgg ccagaacgac cttgcttcgc accttgtctc actacgcagc
    10081 ctttgaacag attgaggtga tttgtgtctt tgatgcccac catgtgccag gtcttcgcca
    10141 gcagtatgac gaattcaagg tatcggtcat ttttacagag gaggaagaga cggcagatag
    10201 ttatatcgaa cgactcagtg cccagctcaa tagtgaccgt cgcaagcagg tttccgtcgc
    10261 aaccagcgac ctcaacgaac aatgggtggt cttttcacaa ggggccttac gggtttcggc
    10321 gcgtgagtta gaggagagaa ccaaggtcat caaaaaggac ttggacaagt ttgtggacca
    10381 ggtagaactc tacaccccac ggctcaatcc ctggtcagat gggaattttc aagccttaaa
    10441 agaaatgatg gaggaaatga aagagtgaca tttacaatcg taaccgattc gacatcggat
    10501 ttgccaatca gctgggtcca agaaaacgat gtgaccgtgc ttggtttgac cattaaccta
    10561 gacggcgcaa cctatgaaac agtcggtgaa aaccgcttga cctctgcaga tttactggag
    10621 aaaatggctt ctggcagcca acccacgacc agtcaggtca atgttggtca gtttgaagaa
    10681 gtttttgaag cggcagccaa ggaagatcat gaggtgcttt atctcgcttt ctcagcagct
    10741 ctttcaggga cctaccagag tgcagttatt gcacgagata tggttatgga ccaatatcca
    10801 gaagcagtca tcaccatcgt tgatacaaag gcagcgacca ttggagaagg ctacttagtc
    10861 atgaaagccg ttgaggcacg tgctgcaggt aagactctgg cagaaaccaa ggcaatcgta
    10921 gaagatttgg tgccgcgttt acgaacctac ctcttggtcg atgaccttaa tcatttggtg
    10981 cgaggtggac gcttgtctaa agcggcagcc ctcattggtg gattggtcaa tatcaaacct
    11041 ctccttgcac tcaatgcgga agggaagtta gaagccattg ccaaaatccg tggtcgtaaa
    11101 aaaggaatta aggaaatgct gaacttgacc ttggacaact tggatcattc tacggtcatg
    11161 gtggcctata caggtgatat tgaggcggca gagggcgtca aatctagttt attggaagac
    11221 gaccgtattt ctgatgttct attgacagaa ttagggcctg tgattgccac tcatacaggg
    11281 acaggagtct tagctatttt atcaattggt acagcaatga gagcctagat tctaagggat
    11341 atttcttgta aagatgtgtc cctttttgtg tgatgacgac ttatgtagaa tagggtaatc
    11401 aaaaggaggt acgataatgc tcattgtcaa gttgttccaa ccagaagcct tggatggctg
    11461 aaactggtgt tttacaggtc ctctggtcta tacggtggat gaattggtct tggaagaatt
    11521 tgataaaacc tttccttata aggagaagct ggtcttgcct ggacaactag ggcagtaaga
    11581 aatttaaaat ggataaggct ttcattctca gcagctctgc tatctttcaa aaaataaaaa
    11641 aagtaaagta aaatagcttg acggacacta gtagatttga taaaatggta gatggtattg
    11701 tttaccccat ttgaaaggcc ccggaacctt ccaaataccc gcggaccgga acatccgccc
    11761 agtaaacaaa aacgattcgt ataggagaaa tcatgaacaa aacaacattt atggctaaac
    11821 caggccaagt tgaacgtaaa tggtatgtag tagacgctac tgatgtacct cttggacgcc
    11881 tttcagcagt agttgctagc gttcttcgtg gtaaaaacaa accaactttc acacctcaca
    11941 ctgatactgg tgacttcgtt atcgtaatca acgctgagaa agtgaaattg actggtaaaa
    12001 aagcaactga taagatctac tacactcact caaaccaccc aggtggcttg aaatcaatct
    12061 cagctggtga attgcgttct aaaaacgctg ttcgtttgat tgagaaatca gttaaaggta
    12121 tgcttccaca caacacactt ggtcgtgcac aaggcatgaa gttgaaagtg tttgtaggtg
    12181 ctgagcacac tcacgctgca caacaaccag aagtacttga tatttcaggt cttatctaag
    12241 ggaaaggacg taatctaaat ggcacaagca caatacacag gtactggtcg tcgtaaaaac
    12301 gcggttgcac gcgtacgttt ggtcccaggt actggtaaaa tcacagtaaa caaaaaagat
    12361 gtagaagagt acatcccaca tgctgacctt cgtttggtta tcaaccaacc attcgcagta
    12421 acttcaacac aaggttcata cgacgttttc gttaacgtga acggtggtgg ttacggtggt
    12481 caatcaggtg cgatccgtca cggtatcgcg cgtgcattgc ttcaagtaga cccagacttc
    12541 cgcgattcat tgaaacgcgc aggtcttctt acacgtgacg ctcgtatggt tgaacgtaag
    12601 aaaccaggtc ttaagaaagc acgtaaagca agccagttta gtaaacgtta atataccgca
    12661 atatatcaac gtttcaaagc actcaagagt cgctttttta taattaggta gtttttatag
    12721 ttacaacgga ttttgattga tgtcataatc ggttcagagt caaatccata ccaattggaa
    12781 atcaaaaggg ttcaggaacc tttgaaggtt gaaaatgaag caaacatagc taccttctta
    12841 aatggttccg tcagtaggga gttgttcatg aaacactttc actatttcta tcaatattcc
    12901 acttaacatt ttcgcttgtt tttgatatac tttagaaaat aggtgttttc aaggggtgat
    12961 accatggaac taaaagatat tatgcatatt ttggaagata tgaaggttgg ggtttttgct
    13021 actttggatg agtatggaaa tccacatgct cgtcatgctc atatcactgc agcaaacgaa
    13081 gaagggattt tctttatgac aagcccagaa acgcattttt atgatcaatt gatgggggat
    13141 caaagagttg cgatgacggc tatttctgag gaagggtacc ttatccaggt agtgcgtgtg
    13201 tgtagaaggg gctgctagac ctgtggagaa cgactatcta aagacagttt ttgcggataa
    13261 tccttattat caacatatct ataaagatga gtctagtgat acaatgcaag tatttcagat
    13321 ttatgctggt catggcttct atcatagctt gactcaaggt cataagtata tcttttctat
    13381 tggtcaaggt gagaattcag aggttcgtgc actttgaaaa ctagttgaaa acatttggta
    13441 agacaagtat atttcaaata attatgatac aatacttttt ataaatgttt taggagtgtt
    13501 tggataaatg agagaagata ttcagatcaa tgagcgagcc cttattttgt cagatcaatt
    13561 ggtggaggta ttggaatcca ttcacgaccc cgagattgag ttggatatat acaatttagg
    13621 acttgtctat gaaattcatc tagatgaaac cgggttttgt aaagtagtta tgacctttac
    13681 tgatgcaggt tgctcatgtg cagatacgat gcctggagag ttagtagcag ctttgaagac
    13741 tattgacgga atagaagatg ctcaggtcga gattgtttgg tctcctgctt ggaaaatgac
    13801 aagaattagt cgcttaggtc gaattactct ggggataagc cctaaataaa agagttgcag
    13861 ttttatttta ctgcagctct tttttaaacg tgtcatcgta ttgtctgtct aattcttcca
    13921 tcgtttcata aatgggtttg ggaatcataa ggacttgagg atccagatcg accataccat
    13981 agcttggatc aatgcattct tcccagtatt ctaaatgttt tttgtcgatg taggattctg
    14041 aatcttcgac ttcaatcccc ccttcggctt ggacagagta ccaatagagg tattcgcgtc
    14101 cgtccaatac ctcacggaag atggtttcga catacatttt ctctccttca agagtgagaa
    14161 gggtgtcttc catgtgctcg ttgagaaagg ccatccattc atctacttga acggttttgc
    14221 cttctttaac acgaaagcgg gagagttcga cgtttagttt cattttttct ccttttggaa
    14281 aaccctaccg cgaggacagg gtcgttgagt tccttatttt ttccccgtac gttctggtct
    14341 ccagaagtcg gtaacggctc ctttagaggc agaggataca gtgtgggcgt attttccgag
    14401 aacgccacga gagtagagtg gtggaataac agttgttttc ttgcgttctt cgatttcttg
    14461 gtcagaaacg tgcatggtga tttctttggt atcttgatca accgtcacca aatcaccagt
    14521 acggaggtag gcaattggcc caccatcctg agcttcaggt gcgatgtgtc ccacaaccag
    14581 tccataggta ccaccagaga aacgaccgtc tgttagaagg gctaccttgt caccttggcc
    14641 ttttccgaca atcatagaag aaagggacag catttcaggc ataccaggac cgccttttgg
    14701 tccaacatag cggacaacga ctacatcgcc atctacgatt tcgtcagtca agactgcttc
    14761 gatagcttct tcttcagaat caaagacctt ggctggacct gtatggttgc ggactttcac
    14821 accagaaacc ttggcaacgg caccttcagg agcaaggtta cctttcaaga taatcagagg
    14881 tccatccgct cgttttggat tttcaagtgg catgatgaca tcttgacctg gagtcaagtc
    14941 tgcaaaattc tttaggtttt cagcaacggt tttacctgta catgtgatgc ggtcgccatg
    15001 aaggaagccg tttttgagca agtatttcat aaccgcaggg acaccgccga cattatagag
    15061 gtcttggaaa acatatttac cagatggttt taagtcggcc aaatgaggca cacgctcttg
    15121 gaaatcgttg aaatcttcca aggtcaaatc aacgttggca gcatgggcaa tggccagcaa
    15181 gtgcagagta gcgttggttg agccgcccag agccattgtg actgtaatgg catcttcaaa
    15241 ggcttcacgc gtcataatgt cagatggttt gatgccaagt tctagcatgc gtacaacagc
    15301 acgaccagct tcttcaatat cagccttctt ctcaggagat tcagcagggt gagaagaaga
    15361 gccaggaata gacatgccca ttacctcaat ggcagtagcc atggtattgg cagtgtacat
    15421 accaccgcaa ccaccaggtc cagggcaagc attacactcg atttgacgaa cctcttcagc
    15481 agtcaagtca ccgttgttcc attttccgat tccttcgaag acagaaacca agtcaatatc
    15541 tttgccattg aggtttcctg gtgcgatggt tccaccgtag gcaaatacgg caggaatgtc
    15601 catattggcg atggcaatca tggaaccagg catgttttta tcacagccac cgattgcgac
    15661 aaaggcatcc acgttgtgcc ctcccatggc tgcctcaata gaatctgcaa tgatatcacg
    15721 tgaagtcaag gagaaacgca tgccaggagt tcccatagcg attccgtctg caacggtgat
    15781 ggtaccgtat tggacaggcc aggcacctgc ttccttgaca ccttctttgg ctaattttcc
    15841 aaagtcatga aggtggatgt tacagggtgt gttttcagcc catgtcgaaa taaccccaac
    15901 aataggcttt tcaaagctat catcggtcat acctgtggca cgcaacatag cacggttggg
    15961 ggatttgacc atcgaatcgt aaacagagct acgatgtcga aagtctttaa gtttgtttgt
    16021 atcggtcata attttcttct ccctatctta ttttacccat tatatcatag atatgaaaga
    16081 aacgataaaa gatttgataa acaattggaa atttccgaat ttttcaacaa tttattctac
    16141 agtaaaaggc acctaagaat gttaagtgcc cttataattt atttgtagat taagaggtcg
    16201 tttttcgatg attatttgcg gatggattga tgaaaagacc gactaacgat agaactagga
    16261 aggctgcgcc gatgtaccaa taaggttgat ctaaggtagt tgaacgtcca gataggttga
    16321 taatgcctcg gagaagacaa ccagctgtaa tagttgcaac gccagaattc cacaaattat
    16381 aagagagacg tgaaagagta ggtataagtt gcagcaaacc gagtagcaca gctccgccta
    16441 ttaatggtac acagaacata taatgcataa agacagagac ttcgccatag ctgagacttt
    16501 catagattcg actgaaaata aacaggaaag ctgttattgc taagtaggag ataaacgttc
    16561 ttgaaactct tgtagttgaa ttagtaaccg atgtagacaa tgtcactcac cgccctttct
    16621 gagatagtat ttccatttgt tgttgggttg ttaataactt gaccgttaaa ataaagagtg
    16681 gatgaaccac cgccatcaag gttgtaggca gtttgagcac catattgttt cataacttcg
    16741 gccaattgat atagagagag tccttggctt tcagacgtac gtccgtctgc tacgacgatg
    16801 atataatgat tttcatcgat aatcccgata gcagaacgag ggttggatga cattgcacgt
    16861 ccgacttctg ttgatgtatc aacgacaatt tcgccgtttt cgaccaatga tggatcaaat
    16921 gctaagaggt tgacaacgcc cttgtcaatc aattcttggg cggtaatctc attttcataa
    16981 atgacctcaa atgagccgtc tgcgtagatg gccaagtcgc cataagctgc attgtcccga
    17041 acggtgtctc gatacagaac cccattctta ataacataac cagttgaatt ggctccatag
    17101 tagtcaccat taaccgctag aatggcattg tttgctgccg cagtttcaga agttttagct
    17161 gttacgttcg tgccataggt attttgggct agagctgtct ttaaatactc tggagagctg
    17221 acttgaatat ctgcgacgta aacagttgtg ttgttggtag tgatggtctc taagttgatt
    17281 tggatattgt catcagtgta actagtatcc gttgtagaga cattcgttgc tgttgtggca
    17341 gtagtggaag acgaagctgt agttgtattc tgctcgctcg tagaagtagc attacttgca
    17401 gcaaccgttg tgatagcctc ggaaagcacg aaggttttta acatggagta agtaaaacct
    17461 cctgtcaaaa gcattccgaa gatggatgcg taggcaaagg gttttttaag caatttcatg
    17521 ggaaaatgat ttcctttctt taaagatgat atttttctga atgaaccaag aggctaggaa
    17581 aaggaagata ccaactgcaa gtttgacaat gtagaggttg agtcctagaa tttggtggaa
    17641 gagatatagg agggctgtat cgcaaaggaa gaggacaagg gctagtgtaa agtagcctac
    17701 gcctgttcgt gcgatgctct cttcattgtt aaagactaat ttcttattaa gtgcaaaatt
    17761 acaggtagcg ctacaaatgc gagcaatcgt gtttgcgacc aataagcgta gagcagttgg
    17821 taagctagtg agtagcaata aggcaagtgc atatattccg tagtcaacta gaaatccacc
    17881 aaaagatgcc agggcaaatt tgaagagatt cttgtaaatg agcagtccat cttttatggg
    17941 acgaaaatgc gaactggcat tatcatcgat ataaatagtt tgaattggaa cttccgtaat
    18001 tttatagcgt tgacttgcct gagttaacat gttcatcttg tactcgtagt ggtcgccttc
    18061 aatatctaac atgaatggaa ttaagtcagt atggaatcca cgcaagcctg tttgggtatc
    18121 ggacacattg acaccagttt gcaatctaaa caatactctg gttagtttgt taccaaatcg
    18181 gctacggagc gggatgtctt tagtaaattg acgaacacca aggatgaggc ggcttggtag
    18241 attcatggct gcgcgtgcga cacggtctat atcattcaca gcgtgttgac catctgaatc
    18301 agcggtaaca gcgacaccag gctttctcaa atcttggatg aaactaaagg ctgttcgtaa
    18361 ggcttggcct tttcctttat tgacatcatg gtggagaaca atggcatagg ttttggcgat
    18421 ttcaagaata tttttggatg cgccagtact accatcatcc acaacgatga cctgacaatt
    18481 tagcctgttt ttcattattt ttaatagttg gattaatttt tcatctggct ggtaagccgg
    18541 tatcactaca taatacatat cctaaacctc atttaatttt tttagtggaa ctactatact
    18601 gatgttttct gaaagcaagc tgaaaccaag ccagtcaagg gatttgctta agttttgctt
    18661 aagaaatgtt aggaaatagt taagaaaacg aacaaatgta ggaattttca gaaaatttct
    18721 tgacattcta cttccttgtg atattatagt agataacaaa tttgcagaga ggaggaatat
    18781 tcgtgcaaga aattcaacta gaccaaccac gttcggggtc ctatctcatt ttggacactc
    18841 tgcatcagct aggagtagac cttgtttttg gttatcctgg tggggcagtt ttgcctctat
    18901 atgatgctat ctatcaatat gagggaatcc agcatatttt ggctcgtcat gaacaaggag
    18961 cggtccacga ggccgaagga tacgctaaat catcaggaaa ggtgggcgta gccattgtaa
    19021 cctctggacc aggtgctacc aatgccatta ctgggattgc ggacgcaatg ggtgatagtg
    19081 ttcctctttt agtttttact ggtcaagtcg caacacgtgg tatcggtaaa gatgcttttc
    19141 aggaagcaga tgtcttgggg atgacaatgc cgattaccaa gtacaattac caaattcggg
    19201 atacggcaga tattcctaga gtcatcacag aagcactcca tattgcgaca acagggagac
    19261 caggtcccgt tgttattgat gttccaaaag atatccaaga aagagttgtt gatttttatc
    19321 atgacccaac tctacaccta ccaagttatc agccaacgat tgaaccaaat ggtttgcagg
    19381 ttaagaaaat tttgaaacag cttagccaag ctcaaaaacc agttatattg gctggtggtg
    19441 gtgtcaatta tgcagatgcc aataaagaat tagttgcctt tgcagagcgc taccgtattc
    19501 cagtagtttc aaccctcctt ggattaggtg caatgcccat tgagcatgaa ttatccttgg
    19561 ctatgggtgg tatgcacggt tcatacgctg ccaatatggc tatggatcag gctgattaca
    19621 ttatcaatat tggagcgcga ttcgatgacc gcctaacagg aaatccaaca acctatgcgc
    19681 caaatgcgac ggtagcacat attgatattg atcccgcaga aattggtaaa gttgtcaaaa
    19741 cggctattcc ggtagtgggc gacgctaagg caaccttgaa agctctgctt gctttagaaa
    19801 cagtcgaaac aggctatgct gattggacgg cacaagtatt ggaaaacaaa cgtcgggcac
    19861 cattttggta tgatgaagat gaaaaggtta ttaagccaca ggcggcaatt gaattaattg
    19921 gtcagttgac gcaaggggat gccattgtcg taacagacgt tggtcagcat caaatgtggg
    19981 ccgctcaatt ctacccctac agacatgcac gccaacttgt aacatctggt ggcatgggaa
    20041 ccatgggctt tggtattcct gcagctatcg gcgccaaatt agccaatcca gataaagaag
    20101 taatcatctt tgttggtgat ggcggcttcc aaatgaccaa ccaagaattg gctattttga
    20161 atggctatgg tgtaccgatt aaggttgtgt tgatcaataa ccactctctt ggaatggttc
    20221 gtcaatggca ggaatccttc tatgaaaagc gtcgtagcca atctgtcttt gacgatgaac
    20281 cgaatttcca attgttggca gaggcctacg gaattagtca ttatagtttt gacaatccag
    20341 cgactctaag tgaagatatg aaagttatct tagaagataa accaatgctc atagaggttc
    20401 atatttctaa tcgtgaacat gttcaaccga tggtgccagc aggtaagagc aatgcagaaa
    20461 tgttgggggt gaagttcaat gcgtagaatg ttaacagcta aattgcgaaa ttcatctggt
    20521 gttctgaatc gttttacagg tgtcctatct cgtcgccaaa tcaatattga gtccatctcc
    20581 gtcggcccaa cagaagtaga tggcatctca cgtgtgacgg tgattgtaga cgtggtcagt
    20641 cacgatgagg tcgaacaaat catcaaacag ctaaaccgct tgattgatgt ggtccgtgtc
    20701 cgtgatttga cggacattcc ccacttagag cgtgaggtga ttcttgttaa aatctcagct
    20761 ccgccaacaa aacgagcaga aattttagcg attatccaac cctttagagc aaatgttgtc
    20821 gatgtagcac ctcactccat taccattcaa atgacaggtg atggagataa gattgacgcc
    20881 ctcctgcgtg tgattcagcc ttatggcatc aagaatatcg caagaacggg tgcgactggc
    20941 tttagtagag actaatcctt ttcgataata agacctatcc tgcgttgatt tggcttgatg
    21001 gacgttagtt ctatcttcgc ctacatcgcc tagtctagcc ttcattttct ttgaacatcc
    21061 aaaactacaa ataaaaatag aaaagagaaa aaattatgac agtaacaatg caatatgaaa
    21121 aagatgtaac agtagcagca cttgacggta aacgtatcgc cgttatcggt tatggttcac
    21181 aaggtcatgc ccatgctcaa aacttgcgtg atacaggaca cgatgtcatc atcggtgtgc
    21241 gtgcaggtaa gtcatttgac aaggcaaaag aagatggttt tgaaactttt gaagtagcag
    21301 aagcagcaaa acaagcagat gttatcatga tcttggctcc agacgaaatc caagcagacc
    21361 tttacaatga agaaatcgct ccaaacttgg aagcgggcaa tgcccttggt tttgcccatg
    21421 gtttcaacgt tcattttgaa tttatcaagg taccagcaga tgtggatgtc ttcatgtgtg
    21481 caccaaaagg tccaggtcac ttggtccgcc gtacctttga agaaggtttt ggagtaccag
    21541 ccctctatgc tgtttaccaa gatgcaactg gcaatgcaaa acatattgcg atggactggg
    21601 caaaaggtgt tggttcagcc cgtgttggtc ttttggaaac aactttcaaa gaagagacag
    21661 aagaagattt gtttggtgag caagctgttc tctgcggtgg tttgacagcc cttatgcagg
    21721 caggttttga agtcttgaca gaagcaggtt atgcaccaga attggcttat ttcgaagttc
    21781 tccacgagat gaaactcatc gttgaccttg tctacgaagg tggctttaag aaaatgcgcc
    21841 aatctatctc aaacactgct gaatttggtg actatgtatc aggtccacgt gtgattacag
    21901 accaagtcaa agaaaacatg aaggcagtcc ttgcagatat tcaatctggt aaatttgcaa
    21961 atgactttgt aaatgactat aaagcaggcc gtccacgtat ggaagcttat cgtaaagaag
    22021 cagagaatct tgaaatcgaa aaagtaggtg cagagctccg caaagcaatg ccatttgtcg
    22081 gacgcaatga tgacgacgca ttcaaaatct ataattaaac actatcatgg tggataggag
    22141 gatagtcagc tttactttga gtgatggcaa tacatttaag gtttgagttg gcggatgagg
    22201 ggatgtcatt cccttttttc cctatctctg aaaatgaata aaagagctgg ttttttccgg
    22261 ctcttttgcc catttcattc atgaatacat taaaaaaata aaaaa
//
LOCUS       DBNFCO010000030        22110 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.030, whole genome shotgun sequence.
ACCESSION   DBNFCO010000030 DBNFCO010000000
VERSION     DBNFCO010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 22110)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22110)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22110
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.030"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(8..1612)
                     /locus_tag="AC1PIV_000966"
     CDS             complement(8..1612)
                     /locus_tag="AC1PIV_000966"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003883 - CTP synthase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006241 - CTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HIP6611998.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITDALKDKIKRAARTTDADVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGSDNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEQPAG
                     QGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNMQAQNMDQIVCDHLKLDVPPADMTE
                     WTAMVNKVLNLQKKVKIALVGKYVELQDAYISVVEALKHSGYANDAAIELDWVNANDL
                     TAENVAERLGQAQGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCVEFA
                     RHVLGLEGANSFELDPETKYPIIDIMRDQIGVEDLGGTLRLGLYPSKLKRGSKAAAAY
                     DNQEVVQRRHRHRYEFNNDFREQFEKAGFVFSGVSPDNRLVEIVEIPENKFFVACQYH
                     PELQSRPNRPEGLYTAFVSAAMENEK"
     gene            complement(1805..2386)
                     /gene="rpoE"
                     /locus_tag="AC1PIV_000967"
     CDS             complement(1805..2386)
                     /gene="rpoE"
                     /locus_tag="AC1PIV_000967"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed RNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HIP6611999.1"
                     /translation="MELNVFAGQEKSELSMIEVARAILEERGRDNEMYFNDLVNEIQN
                     YLEKSNSEIRAALPTFYSDLNVDGSFIPLGENKWGLRSWYAIDEIDEEVITLEEDDED
                     APKRKKKRVNAFMDGDDDAIDYGHDDPEDEDNYPGSVSSEYDDENPDDEKDEVESYDS
                     EINEIIPDDELDEEDVDLGEDDDEYSDEEVVDE"
     gene            complement(2513..5668)
                     /locus_tag="AC1PIV_000968"
     CDS             complement(2513..5668)
                     /locus_tag="AC1PIV_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HIP6612000.1"
                     /translation="MKKKAVVGSVAALVLGMSLCSYQLGRFQAMEEQKNRVSYIEDSQ
                     SVQTTVAEQLTPDQVSAKENIDAEQIVVKITDQGYVTSHGDHFHYYNGKVPFDAIFSE
                     ELVMKDPNYVLQDSHIINEVQDGYVIKVDGKYYLYLKDPSKHKNVRSKEEVERQKGIS
                     SADSKNQAAGNSKDGRYRTDDGYVFNPTDVIEDTGDGFIVPHGDHFHFIPKKDLSAAE
                     LKAAQDYWNQKGSVSSASGSQYGDRNNRAQQTTISAGQGQDLASLLAQLDATPLSQRH
                     VEADGLVFDPRTITKKTAAGVIVPHGDHYHFIPYSQMSPLEEKISRMIGVNGAGVSSG
                     AQASHSQHTLTQPNRPVTPIGTVTTQPVSPTQPVLPTQPKQSTGKVVSYKGRQIPAYG
                     KGLDGKAYFTSDGYTFSKDSITSVDDQGLIASHGDHFHYVGFGELEDFEIKQVEEWVN
                     EKAGKQVPPKTSEQVGNDAKPTTPSQGNDSKPVKPIQEENRPAFEYKQVTAKRKLAGK
                     VVYEMEVGGKTYTYGRDELDLMKISFAELTLAEKDKQYIFDIAPLAEGDLKPAMLVGM
                     DQIPMKGANATYDTGQSFIIPHIDHIHVLPYTWLSKEQIATIRYIMQHPEIRPSAWTT
                     SGHGDGEATDLVPPILNATPKANRLGLKNWQIIHTAEEVMDARAKGKFATNDGYIFSA
                     EDVLDPASFVFSQAFSLPRATGGSLRSISKKDLSKEELEAVQTLLDKRDAEELAKNVT
                     PIEKRAGLKNWQIVHSAEELAEAKAAGKYTTKDGYIFDPADLLDPKVKIGTDNYRIPR
                     VITDGYRRINKSDLNYLSELIPAEAMVAQREKSNSSLPSTPAPTETGASAGETTTPEQ
                     PQVAKETAEEIYNRVEAKKVVPFEALTYNAGYATEVRNGTLVIPHQDHYHYVSFKWFD
                     QGSARSPEGYSLEDFLATVKYYMTNPQERPVSDDGWGVFTPNTPSESTEETETEESDE
                     EIISEETEEIDEFTEELKRRAEEFGMDFKTFEQSLVTLSDRYKVSFEAFEYDAASKVV
                     RLVDKDGVKRTISLPSLEEQV"
     gene            complement(5702..6622)
                     /locus_tag="AC1PIV_000969"
     CDS             complement(5702..6622)
                     /locus_tag="AC1PIV_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter solute-binding protein,
                     Zn/Mn family"
                     /protein_id="HIP6612001.1"
                     /translation="MLKKVIRGCFVALFGFVLAACSAQKEASQVQPGMKIVTSFYPIY
                     SLVKEVSGNKNDVRMIGSRQGIHSYEPSAADIKAIYDADVFIYHSRILESWAGRLEPN
                     LQGSSVKVLEASTNLPLTKVPGLEDMEAGQGIDEASLYDPHTWLDPVLVGQEAVAIGE
                     LLAESDPKNADYYRQNAATLEGKAQKLADKYSPIFLKATSKTFVTQHTAFSYTAQRFG
                     LKQLGIAGVSEEEPSPRQLAEIKEFVDTYNVQTIFTEKGASDKLAKALASSTGVDLKV
                     LDPLEADPENNLTYLENLEQVLETLAQELK"
     gene            complement(6731..7615)
                     /locus_tag="AC1PIV_000970"
     CDS             complement(6731..7615)
                     /locus_tag="AC1PIV_000970"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HIP6612002.1"
                     /translation="MLQRNSLKNLVRPMQKWENVISVGGVVQVSQGVRITDGEVSHYQ
                     LPWSVLPCLQAIEYDCSFLGSRILLDYLQSNLIISGAFGLFYKEYVIAVGGYDRQTLG
                     EDMELVMKLHYFCRNNNIPYRICYETSAICWSQAPSSIGDLCKQRRRWFLGLYQCLKK
                     YRKMLSRVRFGAVGYFSYAYYMLFEFLAPFIETFGCFVILLSLIYHQLNISFFISLFF
                     LHSAFCSLITFASFLQRVYSQDLFIGPMDLCKAFLATLFRYFFLHWVLNIVRLTSFIG
                     YKKRKREWGEIKRVKQFV"
     gene            complement(7666..8949)
                     /gene="tig"
                     /locus_tag="AC1PIV_000971"
     CDS             complement(7666..8949)
                     /gene="tig"
                     /locus_tag="AC1PIV_000971"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HIP6612003.1"
                     /translation="MSVSFEAKETNRGVLTFTIGQDAIKPELDRVFNKVKKDINLPGF
                     RKGHLPRAVFNQKFGEEALYQDVVNALLPAAYEAAVAEAGLEVVAQPKIDVVSMEKGQ
                     DWTITAEVVTKPEVKLGDYKNLAVSVEATKEVTDEEVDAKIEAARNNLAELVIKEGPA
                     AEGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEAQLVGHAAGEEVNVEVT
                     FPEDYQAADLAGKQALFVTKIHEVKAKEVPALDDELAKDIDEEVETLDELKAKYRKEL
                     EASKEVAFDDAVESAALELAVENAEIVELPEEMIHEEVHRAINEFLGGMQQQGISPDM
                     YFQITGTTREDLHKQYEADAEKRTKTNLVVEAVAKAEGFEATEEEINKEIEDLAATYN
                     MEVAQVRSLLSPEMLKHDIAVKKAVEVITSTATVK"
     gene            complement(9171..10190)
                     /locus_tag="AC1PIV_000972"
     CDS             complement(9171..10190)
                     /locus_tag="AC1PIV_000972"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HIP6612004.1"
                     /translation="MKKFKKIILWTLGIVASLGIIAYVSVTNHPQLVVGVIQSFMYKE
                     SSPNSYSPLYDPIDGLKENGQYLKSEIAYSKDYPNSFLDITYPDQNLEADRPTLFYFH
                     GGGFFGGSKNMGAPLSASQATYLIDDIVSKGYNVVNVDYALVPDHHFPTPVIQMNQAI
                     AYMKEHAEEYHLNMDNVVLMGSSAGAIMAAQYGSVLANQEYAQLLNIEPSIAKEDVKA
                     LVIDDAPLDYAKFSLGTKILVGNYVSETIYLSEEEINAYNPISHVNKDYPASFLLGSE
                     DRTDMVSLNKALKQAGVENELVDPLAEEGLEKPHGFVANLRTDPVSAKAFERLMIFID
                     DRTKE"
     gene            complement(10297..11220)
                     /locus_tag="AC1PIV_000973"
     CDS             complement(10297..11220)
                     /locus_tag="AC1PIV_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050525 - cutinase activity [Evidence
                     IEA];
                     GO_function: GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chlorophyllase/cutinase-like alpha/beta fold
                     protein"
                     /protein_id="HIP6612005.1"
                     /translation="MKKVLIGIGILIACFGIGFLYLASKPSVASNYTEVVETGGAVEK
                     KYLGQGNYDVSYLEINALQNFKKYELYYPTNIETETRKFPVVIFSNGTGVRASKYASV
                     LKHLASWGFIVIGTEEEYSWNGFSSEMSLRLAIKLNDNKTVEGLKSNPFFSKVDLDKI
                     GLSGHSQGGVGVFNAVTEQKHGHMIKTIYAASPANLELSSNLEWDYDPSLISVPTFLV
                     SGTGGGYEDLVVSGKQLTQIYETLPATITKVMARRKEAGHGDMLRLPNGYMVAWFMWR
                     LQGAPEAETAFQGNSPEIVQNKLYQDQRIMN"
     gene            11361..11870
                     /locus_tag="AC1PIV_000974"
     CDS             11361..11870
                     /locus_tag="AC1PIV_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014917199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HIP6612006.1"
                     /translation="MERVKRKESLFVESVVEALWELLEDKSFEKISVSELVERAGIGR
                     VTFYRNFSNKEEVLERSFNLESQAWLTERQIDLSDWSDAHLLLALRQFFDFWYEQQDK
                     IRLLTANHLDYLLEEVLDRYFKEKLGDLTDDFHLQFIVGGFFRVLKTWVARGCKESPD
                     DIMRLMSEQ"
     gene            complement(12130..12579)
                     /locus_tag="AC1PIV_000975"
     CDS             complement(12130..12579)
                     /locus_tag="AC1PIV_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HIP6612007.1"
                     /translation="MQISNKFTIAIHALAFIHLFQDQQRVTSKVLANSIQANPVIIRS
                     VLSGLKEAGIVDAKQGSGGFRLAKTLDDISLYDIFVTVDNIDKKGLFNFHENPHPDCI
                     VGGNIHAAVDDKLVQVQTAMEKELKTMYMSDVLVDLEKAIEEKVKRT"
     gene            complement(12589..13764)
                     /locus_tag="AC1PIV_000976"
     CDS             complement(12589..13764)
                     /locus_tag="AC1PIV_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012774962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH:flavin oxidoreductase/NADH oxidase family
                     protein"
                     /protein_id="HIP6612008.1"
                     /translation="MTKILLENLQLPNGQVLDNRFFKSAMSETLADSQGAPSDDLIAL
                     YDFWAKQGVGVLVTGNVMVDGRYLGEPGNVVLDSDAHLAQFRKWAAVGKKNGVPIWLQ
                     LNHPGKQMYRSINQTPIAPSAIPISGGSASAFRPPREMTVFDIKEARDKFIAAGLRAK
                     AAGFTGVQLHAAHGYLTNQFLSPADNQRTDRYGGSLDNRMQFLVEVYQGLREKVGPDF
                     TIALKLNASDFKEEGFGFEDCKHVVKIMSDLGIDLIEISGGNYETPVFGSDYENGAGF
                     VTYALALADLTSVSIVSTGGFRKVTQMEEAIKDGVSMIGLARPFVLRPSLVNDYRQVG
                     DLQADGERTGRYILGGEELVLNSKGESVISYADYAIGMIDEIATGDHLKARISLVSE"
     gene            complement(13757..14626)
                     /locus_tag="AC1PIV_000977"
     CDS             complement(13757..14626)
                     /locus_tag="AC1PIV_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HIP6612009.1"
                     /translation="MPKTILITGSTDGIGKHLAMKLASEGHEVILHGRNSEKLRVALS
                     DIQLKTGSKKIHGYLADFSKLADVYRFSQEIKRDFEQIDVLLNNAGAYFGDARVATAE
                     NIEMTFMLSVQVPYILTTELLPLLEKAAGRVIHTSSLMHHFAQTRGLDFGLEQSYSAA
                     MAYNNAKLYTIWLAIAQAEALEKQGSSVTVNAYHPGLIATNLGNDGIKRNLRSRILTS
                     LMKPFSKDLDQGIETGYYLSLSPEVAGVSGRYFAEKRLANVSLKGFDLAKSQALLAYL
                     DKKIQVFKESYGD"
     gene            complement(14619..15464)
                     /locus_tag="AC1PIV_000978"
     CDS             complement(14619..15464)
                     /locus_tag="AC1PIV_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HIP6612010.1"
                     /translation="MSYITTKNQYITVSNNKIAYRELSKGKSDIPLVMLVHLAATLDN
                     WDPKLLDLLAEKHHVIILDLPGVGASQGKVAPTIPGMAEQAVAIIKALGHEKINLLGL
                     SMGGFIAQEIVRLDSQLVNRLILAGTGPRGGFEVDKVTGKTFRYMLKAGLERVDPKRY
                     IFYNHDEAGRLEAEKVLGRMGQRSAAHADKDMNVPGFLTQLKAIKRWGREPQDDMTFI
                     TQPTLIVNGDKDMQVPTENSYTMHEKIKNSQLIIYPNAGHGSIFQNAEEFSKALLAFL
                     EESNA"
     gene            complement(15490..16491)
                     /locus_tag="AC1PIV_000979"
     CDS             complement(15490..16491)
                     /locus_tag="AC1PIV_000979"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HIP6612011.1"
                     /translation="MKAAQHTSYNKNNIALNLTEIAKPQIKPNQVLVKVTAAGVNPLD
                     NMISRGDVKLIVPYKLPQTAGNEVVGLVEEVGSSVTTFAAGDRVFGRLPLDSIGAFAE
                     YVAVDAQALAKVPAYLTDEEAAAVPLTALTIMQALDLMGAQSGKTIFISGGTGGVGGM
                     AIPIAKAKGLTVITNGDGASAERVLSLGADRFIDYKTEDYTKTLSDVDYVLDTLGGAE
                     TEKQMSIMKKGGQLVSLRAMPNGEFAKRMNLPKWKQILFGLAGRSFDKMAKKYGVHYH
                     FIFVESNGRQLQEVADIFNKLEIKPSIDTVYPFEEVNAALDKVANGRSRGKTVLSFN"
     gene            complement(16571..17002)
                     /locus_tag="AC1PIV_000980"
     CDS             complement(16571..17002)
                     /locus_tag="AC1PIV_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HIP6612012.1"
                     /translation="MDTKFSVALHILTMISESKEILSSQALAESVGTNASYIRKVIAL
                     LKNAGLITSHQGRSGYQLSKSPKDISLLEIYLATQEVEHIRLFQIHQNANLSCPVGQH
                     IEGAMVPIFSSVEQELENQLSRQSLDNVITNLYQSAQVTRI"
     gene            complement(17283..18047)
                     /locus_tag="AC1PIV_000981"
     CDS             complement(17283..18047)
                     /locus_tag="AC1PIV_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612013.1"
                     /translation="MTKGYQQRFSLSILLWMRQDKARQEGMDYWSGGHAQIIAASPGL
                     LEYRQQHLSETEHSFWPKATGLETAVPEDRRIDGIAEVTYQKLLAPIGGRRQTALAFE
                     DEVNVFRRTLMHMGFPYSSRWYHTSTQAQTQLRDVLYFRRKDGVKSGSFKKFVQDGLA
                     SQLATISGVTEVRTQVYLPWNKATWNTPNVAHDNPKEDHLHASIIPGFADQAAREAFY
                     ANQAPQLNAEVVQYSSAVHAYHIEKTLPFVLDGKRM"
     gene            complement(18320..18934)
                     /locus_tag="AC1PIV_000982"
     CDS             complement(18320..18934)
                     /locus_tag="AC1PIV_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1349 domain-containing protein"
                     /protein_id="HIP6612014.1"
                     /translation="MKEFTVKDLVWTRPPRQFTISDEEVTITTHPQTDLWQKTYYHFV
                     NDNAPVLQMETEEDYFSFTVKTDFAGSHTRFDQCGIVLYQDSENWLKCSIEYENDDFQ
                     HLGSVVTNHGFSDWATTEVSSQIKSMWFRLSRRGADYCFENSEDGIHFKQMRVCHFHQ
                     GAGKIAFGLYACSPENSSFTARFTNMELSDCKWQAHDGQEPDEI"
     gene            complement(18934..19500)
                     /locus_tag="AC1PIV_000983"
     CDS             complement(18934..19500)
                     /locus_tag="AC1PIV_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HIP6612015.1"
                     /translation="MLLREIKDQTKQVVQEVLELSDLQKGQIFVLGLSSSEVIGGHIG
                     KNSSLEVGEVVVETILEILDQKGIYLAVQGCEHLNRALVVERELAIQKDLEIVNVLPT
                     LHAGGSGQLAAFKYMKDPVEVEFITAQAGVDIGDTAIGMHIKHVQVPIRPSLREIGQA
                     HVTALASRPKLIGGVRAAYQEDEIRKGS"
     gene            complement(19481..19966)
                     /locus_tag="AC1PIV_000984"
     CDS             complement(19481..19966)
                     /locus_tag="AC1PIV_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HIP6612016.1"
                     /translation="MRNKQTQELVLLAILTALSLVLAFVHVPTATGFVTLLDVGVYFT
                     AFYLGKKEGAIVGGLSGLLIDFLLGYPQWAFFSLVFHGAQGYFAGWTGKKRILGLVLA
                     TLSMVGGYYLASRLYFNDLKAIESVLSNTLQNTVGLVVGYVLAQAIERIGAVNHVIKG
                     N"
     gene            complement(19956..20717)
                     /locus_tag="AC1PIV_000985"
     CDS             complement(19956..20717)
                     /locus_tag="AC1PIV_000985"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004184219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HIP6612017.1"
                     /translation="MKTKYILALSGNDIFSGGGLHADLTTYTVHGLHGFVAVTCLTAM
                     TEKGFEVIPTETAVFAQQLASLKDVPFSAIKIGLLPSVEIAEQALEFIKTHQEIPVVL
                     DPVLVCKETHDTEVSQLRDEILKFLPYVSIITPNLAEAQLLLQKDIKTVEEMKQVAVV
                     LYDLGAKAVVIKGGNRLGGSEAVDVFYDGQEVVVLQSPLLSENNVGAGCTFASSIASQ
                     LLLGQEPLEAVRLSKDFVHAAIEKSDDYGVVQYEK"
     gene            complement(20707..21456)
                     /gene="truA"
                     /locus_tag="AC1PIV_000986"
     CDS             complement(20707..21456)
                     /gene="truA"
                     /locus_tag="AC1PIV_000986"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HIP6612018.1"
                     /translation="MTRYKAIISYDGHDFSGFQRQPHARTVQEEIEKTLVRLNSGQPV
                     TVHGAGRTDAGVHAYGQVIHFDLAGSRDVEKLRFALDTQTSEDIDVVSVEQVADDFHC
                     RYAKHSKTYEFLVDIGRPKNPMMRHYATFYPYDLDLSLIEEAIQDLVGTHDFTGFTAS
                     GTSVEDKVRTITVASMEYDQQRQFLIFTFSGNGFLYKQVRNMVGTLLKIGNGRMPVGQ
                     IKRILAEKDRGLAGPTAAGNGLYLKEIIYED"
     gene            21623..22078
                     /locus_tag="AC1PIV_000987"
     CDS             21623..22078
                     /locus_tag="AC1PIV_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HIP6612019.1"
                     /translation="MELHSHFNAENQTAFEHVIQHLKEKGIRITETRKAVVAYIIESD
                     DHPSAEMIYQDLIPNYPNMSLATVYNNLKLLLEEGFVTKLKRTNDNTTYYDFMGHEHL
                     NVICEVCGKITDFMDVEIPSLKKEAHTQTGYKITKEVLSIYGICPDCQN"
BASE COUNT         5970 a         5117 c         4362 g         6661 t
ORIGIN      
        1 gttatactta tttttcattc tccatagctg ctgaaacaaa ggctgtatac aaaccttcag
       61 ggcgattagg acgagattgt agttctggat ggtattggca ggcaacgaag aatttatttt
      121 ctggaatttc aacaatttct accaaacggt tgtctggtga cacgcctgag aaaacaaaac
      181 ctgctttttc aaattgttca cggaagtcat tattaaactc ataacgatga cgatggcgac
      241 gttgtacaac ttcttgatta tcataagcag ctgcagcctt ggagccacgt ttgagcttgc
      301 ttggataaag acctaaacgg agagttcctc ctaaatcttc cactccaatt tgatcacgca
      361 tgatgtcaat aattggatat tttgtttctg ggtctaattc aaagctgtta gcaccttcta
      421 aaccgagaac gtgacgtgca aattctacac aggtcagctg cattcccaag cagaccccta
      481 gcattggcac gtcattctca cgagcataac gaatggcttg tattttccct tctgtaccac
      541 gttgtccaaa gccaccagga acgataattc cttgtgcttg tcctagacgt tcagctacgt
      601 tttctgctgt caaatcattt gcattgaccc agtccaattc gatagcagca tcatttgcat
      661 atcctgagtg ttttagagct tcaactacag aaatataggc atcttgtaat tctacatact
      721 taccaactaa agcgattttt acttttttct ggagattaag aaccttgttt accatcgctg
      781 tccactctgt catatctgct ggaggtacgt cgagcttcaa gtgatcgcaa acaatttgat
      841 ccatgttctg tgcttgcata tttaatggga tttggtaaag atgttcgaca tccaaggact
      901 caataactgc ttctggagca acatcacaga attgtgccag tttattttta attccttgtc
      961 cagcaggctg ctctgtccga attaccaaca tgttgggctg aatacctaga ccacgcaact
     1021 cttttacaga atgttgtgtt ggcttagttt tcatttcgcc tgctgctttg agataaggca
     1081 agagtgttgt atggatatac ataacattgt ctgaaccgac atctgccttc atctgacgaa
     1141 gcgcttcaag gaatggcaag ctttcaatat cacctactgt accacccact tctgtgatga
     1201 tgacgtctgc atctgtagta cgagctgcac gcttgatttt gtctttcaaa gcatctgtaa
     1261 tgtgtggaat aacttgaact gttgccccta agtattcccc tttacgctct ttacggagga
     1321 cttcgctata aattttacct gttgtaacat ttgaatattt gttcaggtta atgtcgatga
     1381 aacgctcata atgcccaagg tccaagtcgg tttctgcacc gtcatccgtc acaaaaactt
     1441 caccgtgttg atacggactc attgttcccg ggtcaatgtt gatgtatgga tcaaattttt
     1501 ggattgttac cttgagacct cgattcttca ataaacgacc taggctggct gctacaatcc
     1561 ctttgccgat agaggaaaca acgccacctg ttacaaaaat atactttgtc atgcaaactc
     1621 cttttctacg attcaggcta ataggaagca atttgtgggg atacttcctg ttaacttgaa
     1681 gaaaaaacaa aaatagctcc ctatcgctag ggagctccga cctcaaaaga ggtgcccgat
     1741 aatatcttat cgtaattcag tagtcttgtc aaattatttt taagaatcta tggggatata
     1801 attcttattc gtcgacgacc tcttcatctg aatactcgtc gtcatcttca cctaaatcaa
     1861 catcctcttc atccaattcg tcatctggga taatttcgtt gatttctgaa tcataggact
     1921 caacttcatc tttttcgtca tctggatttt catcatcgta ttctgatgat acactacctg
     1981 gatagttatc ctcatcttcc ggatcatcat gtccatagtc aatcgcatca tcatcaccgt
     2041 ccataaaggc attgacgcgt ttcttcttgc gttttggtgc atcttcatca tcttcttcaa
     2101 gagtgatcac ttcttcgtcg atctcatcga ttgcgtacca tgaacgtaag ccccatttgt
     2161 tttcgccaag cggaatgaag cttccatcca cattcaaatc agaatagaag gttgggaggg
     2221 ctgcgcgaat ctcgctgttt gatttttcaa ggtagttttg aatttcattg accaaatcgt
     2281 tgaaatacat ttcgttgtca cgtccacgtt cttccaaaat agcacgggct acttcaatca
     2341 tggaaagttc gcttttttct tgtcctgcaa atacgttaag ttccaaggct gttctccttt
     2401 tttgtctttc ccttctattt tacgctaaaa aaggcaaata gtcaaagata atctttatcg
     2461 tttttctgta aaaaaatacc tgcagagctc agtgctacag gtattttgtt tactatactt
     2521 gttcttctaa acttggaagg gagatggtcc gtttgacccc atccttatct acaagtcgaa
     2581 caactttgct tgctgcatca tattcgaaag cttcaaaaga aactttgtaa cggtctgaga
     2641 gtgtgaccag actttgttca aaggttttga agtccatgcc aaactcttct gctcttcgtt
     2701 ttaattcttc tgtaaactcg tcaatttcct cggtttcttc agaaataatt tcttcatcac
     2761 tttcttccgt ctctgtttct tctgttgatt cagatggtgt atttggtgta aatactcccc
     2821 agccatcgtc tgaaactggg cgttcttgtg gattagtcat gtagtattta accgttgcta
     2881 ggaaatcttc taaactatac ccttcaggac ttcttgcact accttggtca aaccatttaa
     2941 aggatacata gtgatagtga tcttgatgcg gaatcaccag agtcccgttg cgtacttcgg
     3001 ttgcatagcc agcattgtaa gtcagtgctt cgaaaggaac gactttcttc gcttccactc
     3061 ggttataaat ttcctctgct gtttctttgg caacttgtgg ctgttctggc gttgttgtct
     3121 cgcctgcact tgctcctgtt tcagttggtg caggtgttga cggtaaacta gaattagatt
     3181 tctcacgttg agccaccata gcctctgctg ggatcagctc gcttaagtaa ttcaaatcac
     3241 tcttgttaat ccgacggtaa ccatctgtaa tcacacgtgg gatgcgatag ttatccgtac
     3301 ctattttcac tttgggatct aataggtccg ctgggtcaaa aatatagcca tcttttgttg
     3361 tatattttcc tgctgcctta gcttctgcca attcttctgc tgagtgaaca atttgccaat
     3421 ttttcaaacc tgcacgtttc tcaattggtg tgacattttt cgccaattct tcagcgtctc
     3481 gtttatcaag aagagtttgt acagcttcca attcttcttt agataaatct ttcttggaaa
     3541 ttgaacgtag agaacctcct gtcgctcttg gtagactgaa cgcttgacta aagacaaaac
     3601 ttgctggatc tagtacgtct tccgccgaga agatatagcc atcatttgtc gcaaatttcc
     3661 cttttgcacg cgcatccata acttcttctg ctgtgtgaat gatttgccaa tttttcaagc
     3721 ctaagcggtt tgctttaggt gttgcattta gaattggggg aacaagatcc gttgcttctc
     3781 catcaccatg tccacttgta gtccaagcag atggacgaat ttcaggatgt tgcatgatat
     3841 agcggatcgt tgcaatttgt tccttactca accatgtgta aggtaggacg tggatgtgat
     3901 caatgtgtgg aataataaag gattgtccag tatcataggt cgcattcgct cccttcatcg
     3961 gaatttgatc cataccgacc aacatggctg gcttaagatc tccttctgca agcggtgcaa
     4021 tatcaaagat atactgctta tctttttctg ccaaagtcaa ctcagcaaaa gagatcttca
     4081 tcaaatctag ttcgtcacga ccatacgtat aagtttttcc acctacttcc atttcataaa
     4141 caacttttcc agccaattta cgtttagccg ttacttgttt atattcaaat gcagggcggt
     4201 tttcttcttg aattggtttt acaggttttg aatcattccc ttgacttggt gttgtgggtt
     4261 tagcatcgtt tcctacttgt tcagatgttt tcggtggcac ttgtttgccc gccttctcat
     4321 taacccattc ctctacttgc tttatttcaa aatcttcgag ttcgccaaaa ccaacataat
     4381 ggaaatgatc tccatgacta gctatcaacc cttgatcatc aactgaggta atagagtctt
     4441 tgctaaaggt gtatccatca cttgtaaaat atgccttacc atctaaccct tttccgtaag
     4501 caggaatttg acgtccctta taggaaacca ctttccctgt tgactgcttc ggttgtgttg
     4561 gtaatactgg ttgtgtaggc gataccggtt gcgttgtaac agtgccgatt ggtgttactg
     4621 gacgatttgg ttgtgttagt gtatgttggg agtgacttgc ttgtgcgcca gaagaaacac
     4681 ctgctccatt tacaccaatc attcgagaaa tcttctcttc tagaggagac atctggctgt
     4741 atggaataaa gtggtaatga tcgccgtgtg gaacgatgac acctgctgcg gttttcttcg
     4801 taatcgttct tgggtcaaat accaatccat ccgcttctac atggcgttga gataggggtg
     4861 ttgcatccaa ttgagccaat aaactagcca aatcctgacc ttgccccgca ctaattgtgg
     4921 tctgttgagc tctattattt ctatcgccat attgactacc actagccgag ctcacacttc
     4981 ctttttgatt ccagtaatct tgagcagcct tcaattcggc agctgataaa tcttttttag
     5041 gaataaagtg gaaatggtcg ccgtgcggaa cgataaaacc atctcccgtg tcttcaataa
     5101 catctgtcgg attaaagaca tagccatcgt ctgttctgta gcggccatcc ttactatttc
     5161 ctgctgcctg atttttgctg tcagcagaag agattccttt ttgccgctcc acttcttctt
     5221 tgctacgaac atttttatgt ttgctagggt cttttagata gagatagtat ttcccatcaa
     5281 cttttatgac gtagccatcc tggacttcat taatgatgtg actgtcttgt aagacatagt
     5341 ttgggtcctt catgaccaac tcttcactaa aaatcgcatc aaaggggact ttaccattat
     5401 agtagtggaa atggtcaccg tgtgatgtca catagccttg atcagtaatt ttaacgacta
     5461 tctgctcagc gtcaatattt tccttggcag aaacttgatc aggtgttaat tgttcagcaa
     5521 cggtagtttg cacactttga ctatcttcaa tataggacac acgatttttt tgctcttcca
     5581 tcgcttggaa acgtccaagc tgatagctac agagactcat ccctaaaaca agggcggcta
     5641 cggagccaac aactgctttt ttcttcattt tttctccttt cggtcgatag aattcggcct
     5701 tttattttaa ctcttgagct aatgtttcta agacttgctc tagattttct agataggtta
     5761 aattattttc tggatctgct tcaagaggat ccaacacttt taaatctaca cctgtcgaac
     5821 tcgccaatgc cttggcaagc ttatccgagg cacctttttc tgtaaaaatt gtttgcacat
     5881 tgtaggtgtc aacaaattct ttaatttccg ccaactgtct aggacttggt tcttcctctg
     5941 aaactcctgc gatccccaac tgcttcaacc cgaagcgttg cgcagtgtaa gagaaggctg
     6001 tgtgttgagt gacaaatgtt tttgatgtgg cttttaaaaa gattgggcta tacttgtctg
     6061 ccaacttttg cgcctttccc tctaaagttg cggcattttg acgataataa tccgcattct
     6121 taggatcact ttctgctaaa agttcaccaa tcgcaacagc ttcctgacca accaaaactg
     6181 gatccagcca tgtgtggggg tcatataaac tagcttcatc aatcccttga ccagcttcca
     6241 tgtcttctaa ccctggaacc tttgtcagcg gtaaatttgt cgaagcctcc aaaaccttga
     6301 cagatgaacc ttgcaaatta ggttccaaac gtcctgccca ggattccaaa attcgcgaat
     6361 gatagataaa aacatctgca tcgtatatgg cctttatgtc cgcagccgat ggttcataag
     6421 agtgtatgcc ctgtcttgag ccaatcattc gaacatcatt tttattccct gacacttcct
     6481 taaccagtga ataaatcggg taaaatgagg tgactatttt cattcctggc tgtacttgac
     6541 tcgcttcctt ctgagccgag caagctgcta aaacaaaacc gaataaggca acaaaacagc
     6601 ctcttatcac tttctttaac ataacttcct cctttgttaa ccagttaact ataacacaag
     6661 aatattaacc agtcaagtat tttttaaaaa aagataagac tttcttttta taagccagtc
     6721 ttacctttac ttaaacgaat tgtttcactc gtttgatttc tccccattca cgctttctct
     6781 ttttatatcc aataaaactt gtcagacgga caatattcaa tacccaatgc aagaaaaaat
     6841 atctaaacaa ggttgccagg aaggctttac acaaatccat aggtccaata aataaatctt
     6901 gcgagtagac gcgttgcaaa aatgacgcaa aggtgattag tgagcaaaaa gcactatgga
     6961 ggaaaaagag cgatatgaaa aatgagatgt ttagttgatg atagatcaac gaaagtagaa
     7021 tcacgaaaca accgaaagtc tctataaacg gagccaaaaa ttcaaatagc atatagtaag
     7081 cataggaaaa atatcccacc gccccaaaac gaactcgcga taacattttt cggtattttt
     7141 ttagacattg atagagtccc aagaaccagc gacggcgttg tttgcataaa tcaccgatag
     7201 agctcggtgc ttgactccaa caaatggcgc tggtttcata gcagattcga taaggaatat
     7261 tgttatttct acagaaataa tgcaatttca tgactagctc catatcttct cccagtgtct
     7321 gcctatcata acccccaact gctatgacat actccttgta aaataaccca aaggcacctg
     7381 atatgatgag attggattgc aaatagtcca ataaaattct actccctaaa aaagaacagt
     7441 catattcgat agcttgtaaa catgggagca ccgaccacgg caactggtaa tggctgacct
     7501 ctccgtcagt tattcgtacc ccttgtgaaa cttggacgac tccaccaaca gatatgacat
     7561 tctcccattt ctgcatggga cggacaaggt ttttcagaga gtttctttgt aacatcgaaa
     7621 gatgattaaa caaaaaaccc gaccagagtc gagttttcca aataattatt ttacagttgc
     7681 agtgcttgta atcacttcta cagctttctt cacagcgatg tcgtgtttaa gcatttctgg
     7741 tgaaagcaag ctacgaactt gtgccacttc catattgtaa gttgctgcca agtcttcgat
     7801 ttctttgttg atttcttctt cagttgcttc gaaaccttct gctttagcta ctgcttcaac
     7861 aaccaagttt gtcttagtac gtttttcagc atctgcttcg tattgtttat gaaggtcttc
     7921 acgagttgta ccagtgattt ggaagtacat atctggtgag ataccttgtt gttgcatacc
     7981 acccaagaat tcattgattg cacggtgaac ttcttcatga atcatttctt ctggcaattc
     8041 aacgatttca gcgttttcta cagccaattc aagagctgct gattcaactg catcgtcaaa
     8101 ggcaacttct tttgatgctt ccaattcttt gcggtattta gctttcaact catcaagtgt
     8161 ttccacttct tcgtcgatgt cttttgccaa ttcgtcatcc aaagctggaa cttcttttgc
     8221 ttttacttca tggatttttg ttacgaagag ggcttgttta ccagcaaggt cagctgcttg
     8281 gtagtcttct gggaaagtca cttcaacgtt tacttcttca ccagctgcgt gaccaaccaa
     8341 ttgcgcttca aaacctggga tgaattgacc tgaaccaagt ccaagtgaga agttctcacc
     8401 tttaccgccg tcaaattcaa caccgtcgat tgaacctaca aagtcgataa caactgtatc
     8461 gccttcagct gctggacctt ctttgataac caattcagcc aagttgttgc gtgcagcttc
     8521 gatttttgcg tcaacttctt cgtctgttac ttctttagta gcttctactg aaactgccaa
     8581 gtttttgtag tcacccaatt ttacttcagg ttttgtcaca acttccgcag tgattgtcca
     8641 gtcttgacct ttttccatag atacaacgtc gatttttggt tgtgcaacga cttcaagacc
     8701 agcttctgca accgctgctt cataagctgc tggtaacaat gcatttacaa catcttgata
     8761 aagtgcttct tcaccaaatt tttggttgaa aacggcacgt ggcaagtgac ctttacggaa
     8821 acctggaaga ttgatatctt tcttaacttt gttgaaaacg cgatccaatt ctggtttgat
     8881 agcatcttga ccgattgtga aagtcaaaac gccgcgattt gtttcttttg cttcaaatga
     8941 tacagacatt ctgtcattct ccttaaaatt ttattgcata ctcttcatta taacacaatt
     9001 gacaaggatt tcaacgattt tataacgtac ttttgggaaa tggcagagct gggacttatt
     9061 gttctcactt ggaatttttc ggcgtagact ttctgagtac aaacatggtt gtcagagcga
     9121 cagattgatt ggacaaatcc ctatcagttt ccaacttatc aacactccga ctattccttg
     9181 gttctatcgt ctataaaaat catcaaccgt tcaaatgctt tggcagacac agggtctgtt
     9241 cgtaaattcg ccacaaaacc atgaggcttt tcaagccctt cttctgccaa aggatcgacc
     9301 aattcatttt caactcccgc ttgcttcaaa gccttgttga gcgacaccat atctgttcga
     9361 tcctcgcttc ccagaaggaa actagctggg tagtctttat tcacatggga aatagggtta
     9421 taggcattga tttcttcctc acttagatag atggtttctg aaacataatt tccaaccaag
     9481 atcttcgtac ctaggctaaa tttggcataa tctaaaggag catcgtctat aaccagagcc
     9541 ttgacatctt cttttgcaat acttggttca atattcaata gctgagcgta ctcttgattg
     9601 gctaagacgc taccatattg tgccgccatg atggcacctg ctgatgaacc catcaagacg
     9661 acattgtcca tgttcaagtg atattcttca gcgtgttcct tcatgtaggc gatagcctga
     9721 ttcatttgaa tcactggcgt tgggaaatgg tggtctggta caagagcata atccacattg
     9781 acaacattat atccttttga cacgatgtca tcaatgaggt aggtcgcttg gctagctgac
     9841 agaggggccc ccatattttt gctacctcca aagaatccac caccgtggaa atagaagagg
     9901 gttggtcggt cagcttcaag attttggtct ggataggtaa tatctaaaaa actgttggga
     9961 tagtccttac tataggcaat ctcacttttc aaatactgac cattttcttt cagaccatca
    10021 atgggatcat aaagaggact gtaagagttc ggtgaactct ctttgtacat aaacgattga
    10081 atgacaccga ctaccaactg cggatgattg gtaacagaca cataagcaat gataccgaga
    10141 ctggctacaa tcccaagggt ccataagatg atttttttga attttttcat gaagaattac
    10201 actcttttta cacatttttt gaataagcta ctaacataaa acaagaacaa acaatagaaa
    10261 gacagaactc gcttttgacc gtcaatgata caaatcctag ttcattattc tttgatcttg
    10321 atagagtttg ttttgaacaa tttctgggga gtttccttga aatgccgtct ctgcttcagg
    10381 ggctccttgt aaccgccaca taaaccaagc taccatatag ccgtttggaa gtctaagcat
    10441 atcaccatgt cctgcttctt ttctccgagc cattaccttc gtgatggtag ctggtaatgt
    10501 ctcataaatc tgtgtcaact gcttgccaga cactaccaaa tcctcatatc cacctcccgt
    10561 acccgatact agaaaggtcg gaacagaaat caagctcggg tcatagtccc attctaaatt
    10621 actagaaagt tctaaattgg caggacttgc cgcgtaaata gttttgatca tatgcccatg
    10681 cttttgttcc gtaacagcat taaagacccc aactcctcct tgagaatgcc ccgataggcc
    10741 gatcttatct aaatcgactt tactaaagaa aggatttgat tttaggcctt caacagtctt
    10801 attatcattt agcttgatag caagtcgcaa gctcatttcg gatgaaaatc cattccaaga
    10861 atattcttcc tcagtaccaa tgacaataaa gccccaagaa gccaaatgtt tcaaaacaga
    10921 cgcatactta gaagctctaa caccggtacc attagaaaat atcactactg gaaattttct
    10981 ggtttctgtt tcaatatttg taggatagta cagttcatat tttttgaaat tttgtaaagc
    11041 attgatttcg agataggaaa cgtcatagtt gccctgtcca agatactttt tctcaacagc
    11101 tccacccgtt tcaactactt ctgtgtagtt agaagccact gatggcttgc tggctaaata
    11161 caggaaacca ataccaaaac aagctattaa aatcccaatg ccgattaaaa cttttttcat
    11221 actttctttt ttctgtcctt tatggtatat ttttagaaac aagtgtttcg tttttatcag
    11281 tatagcagat ggacagtggg aaaactagtc ccagctctgc tatttcccca aaaggaaaca
    11341 aaggaaagga agtgtttcgc atggaaagag tgaagcggaa agagtcatta tttgtggaga
    11401 gtgtcgtgga ggctctgtgg gagttactgg aagacaaatc ttttgaaaag attagtgtgt
    11461 cagagttggt ggagcgagct ggcatcggtc gggtgacctt ttaccgaaac ttttccaata
    11521 aggaagaggt gctcgaacga tccttcaact tggaatcgca agcctggttg accgaacggc
    11581 agattgactt gtcggattgg tcagatgctc atctcttact agctttacgg caattttttg
    11641 acttttggta tgagcaacag gataagattc gcttattgac tgccaaccat ttggactact
    11701 tgctcgagga ggtcttggat cgctatttca aagaaaaact gggggacttg actgatgatt
    11761 ttcacctgca atttatcgta ggaggatttt tccgagtgct caaaacctgg gttgctcgag
    11821 gctgtaagga aagccctgat gacatcatgc ggttgatgag tgagcaatag agcaagcttg
    11881 tcaacgttct tgaccaaacc aagcaaaaag acttagacaa ctgatgttca gtcactctaa
    11941 gtctttttgt gtatagtgag gatgggcaaa aagcccagga ccactactta gagttcgtgt
    12001 caacatctca gcgcagtggt tgattggcag atttgttcgt gttttacact ccaaatctga
    12061 cctaatcaac tgtgcggggg tgggaagacg aactcttcta tgaatggtcg agttctttcc
    12121 cactcccatt taagtccttt tcactttttc ttcaatggct ttttctaggt caaccagaac
    12181 atcggacata tacatagttt tcaattcttt ctccatagct gtctggactt ggacgagttt
    12241 gtcgtccaca gcagcatgga tatttccccc cacgatacag tcgggatggg gattttcatg
    12301 aaagttgaac aagcctttct tatcaatatt gtcaaccgta acaaagatgt cataaagact
    12361 aatgtcatca agcgtctttg ctaaacgaaa accgccgcta ccctgcttgg catctacaat
    12421 tcccgcttcc ttcaaaccag atagaaccga gcgaatgata acgggattgg cttgaatact
    12481 gtttgccaaa accttgctgg tgacacgttg ctggtcttga aagagatgga taaaagccaa
    12541 ggcatgaatg gcaatggtaa atttatttga aatctgcata acaatctttt actcactgac
    12601 aaggctgata cgtgctttga gatgatcacc tgttgcaatc tcgtcaatca taccaatggc
    12661 ataatctgca taggaaataa cgctttctcc cttgctgttc aagaccaact cttcaccgcc
    12721 aagaatataa cgacctgtcc gttcgccgtc tgcttgcaaa tcaccgactt gacggtaatc
    12781 attgacaaga cttggacgaa ggacaaaggg tctagcaaga ccaatcatgg acacaccatc
    12841 cttgatagcc tcctccatct gagtgacttt tcggaaaccg cctgttgaaa caatagaaac
    12901 agaagtcaaa tctgctagag caagggcata ggtgacaaat ccagcaccat tctcatagtc
    12961 actaccaaaa acaggtgtct cataattgcc acctgaaatt tcaatcaggt caatacccaa
    13021 gtcagacatg attttcacca catgcttaca atcctcaaaa ccaaaaccct cttccttaaa
    13081 atcagaagca ttcaatttca aggcaatggt aaaatctggt cccacttttt cacgcagacc
    13141 ttgataaact tccaccaaga attgcatgcg attgtccaga ctgccaccat agcggtccgt
    13201 ccgctgatta tccgctggtg agaggaattg attggtcaag taaccatgtg cagcgtgtaa
    13261 ctgtacacct gtaaatcctg ctgcttttgc cctaaggcct gctgcaataa atttatctct
    13321 ggcttctttg atgtcaaaca cagtcatttc tctcggtgga cgaaaggccg aagctgaacc
    13381 tccagaaatc ggaatggcac tgggtgcaat cggagtttga ttgatcgacc gatacatctg
    13441 tttgccagga tgattgagct ggagccagat aggcacaccg ttctttttcc caacggctgc
    13501 ccatttccga aattgagcca gatgagcgtc tgaatcaagg accacattgc ccggctcacc
    13561 aaggtagcgg ccgtccacca tgacattgcc tgtcactaag acacccactc cctgcttggc
    13621 ccaaaaatca tataaggcaa tcaggtcatc tgagggagct ccctgactat ctgccagggt
    13681 ttcgctcata gcggatttga aaaagcgatt gtctaagacc tgaccattgg gcagttggag
    13741 gttttctaac aaaatcttag tcaccgtagc tctccttaaa tacttgaatt ttcttatcaa
    13801 gataggctag taaggcttgg ctctttgcca aatcaaatcc tttcaagctg acattagcca
    13861 accttttctc cgcaaaataa cgacctgata ctccagccac ctctggtgac aagcttaagt
    13921 agtaacccgt ttcaatcccc tggtccaaat ccttggaaaa tggtttcatc agactggtga
    13981 gaatccgact tctcagattg cgtttgatac catcattgcc caaatttgtc gcaatcaagc
    14041 caggatggta ggcattgacg gtcacagatg aaccttgctt ttctaaggcc tctgcctgag
    14101 ctattgccag ccaaatggtg taaagcttgg cattattgta agccatggct gcagaatagc
    14161 tctgctctaa accaaaatcc aagcctctgg tttgtgcaaa atggtgcatc aaggaagagg
    14221 tatgaatgac cctgcctgct gctttttcca gcaagggaag taactccgtc gtcaagatat
    14281 acggaacttg gacagacagc ataaaggtca tctcgatatt ttctgccgtt gctacacgcg
    14341 catcaccaaa gtaagcaccc gcattgttta acaagacatc aatctgctca aaatcgcgtt
    14401 taatttcttg gctgaaacga tagacatctg ctaacttgga aaagtctgca aggtagccat
    14461 gaattttttt acttcctgtt tttagctgaa tgtcactgag agctacacgg agcttttcgc
    14521 tatttctccc gtgcaaaatc acttcatggc cttcactagc tagtttcatg gctaggtgtt
    14581 tgccaatccc gtctgtcgat cctgtgatta aaatagtttt aggcattgct ttcctccaaa
    14641 aaggctagta aggcttttga aaactcttct gcattttgga agatcgagcc gtgtcctgca
    14701 tttggataaa taatcagttg gctatttttg attttttcat gcatggtata agaattttct
    14761 gtcggaactt gcatatcctt atcaccgttg acgatcagag ttggttgggt aataaaggtc
    14821 atgtcatctt gcggctctct tccccagcgt ttgatagctt tcagctgggt caaaaatcct
    14881 ggaacattca tgtccttgtc tgcatgtgca gcacttcttt gccccatacg acccaagact
    14941 ttttctgcct ccaaacgacc tgcttcatca tgattgtaga aaatgtagcg ttttggatcc
    15001 acacgctcta aaccagcctt cagcatatag cggaaggttt ttccagttac cttatcaact
    15061 tcaaaaccac cacgaggacc tgtacctgct aaaatcaatc ggttgaccag ctgactatcc
    15121 agacgaacga tttcttgagc aataaaacca cccatagaca gacccagcaa attgattttc
    15181 tcatgaccca aagccttgat aatagcaaca gcctgctcag ccattcctgg aatagtcgga
    15241 gccaccttgc cttgactagc tcctacgcca ggaaggtcta ggataattac atggtgcttt
    15301 tcagccagca aatccagcaa tttgggatcc cagttgtcca aggtggccgc taggtggacc
    15361 agcatgacca aaggaatgtc agacttgccc ttgctgagct cacgataggc gattttattg
    15421 tttgaaacgg tgatgtattg gtttttggtt gtaatatatg acatgatttt tccctgtata
    15481 ttttattttt tagttgaaac tgaggactgt ttttccgcgt gaacgaccgt tggcaacctt
    15541 atcaagtgct gcgttgactt cttcaaatgg ataaactgta tcgattgacg gtttgatttc
    15601 gagcttgttg aaaatgtctg ctacttcttg cagttggcga ccattgctct ctacgaaaat
    15661 gaaatggtag tgaacaccgt atttttttgc cattttgtca aatgaacgac cagctaggcc
    15721 aaacaagatt tgtttccatt ttggcaaatt catacgtttg gcaaattcgc catttggcat
    15781 ggcgcgaagg gaaaccagct gtccaccttt tttcatgatt gacatttgtt tctctgtttc
    15841 tgcaccacca agtgtgtcca agacgtagtc aacatcgcta agtgttttgg tgtaatcttc
    15901 tgtcttgtag tcgataaaac ggtctgcacc caatgacaac acccgctctg cacttgcccc
    15961 atcaccattt gtgataacgg tcaagccctt ggctttggca atcggaatgg ccatacctcc
    16021 gacaccacca gttccgcctg agatgaagat ggtcttgcca gattgtgccc ccataaggtc
    16081 aagtgcctgc atgatggtca gagctgtcag aggaacggca gctgcttctt catctgtcaa
    16141 gtaggcagga accttagcaa gagcctgagc gtcaaccgct acatactcag caaaagcacc
    16201 gatactatca agcggaagac gaccgaagac acgatcccct gctgcaaagg tcgtcacgct
    16261 tgaacctact tcttcaacca agccaaccac ttcatttcca gctgtttggg gcaatttgta
    16321 agggacaatc aatttcacat ctccgcgtga aatcatgttg tccaaggggt taacgcctgc
    16381 tgcggtcact ttgacaagga cttggttagg cttgatttgt ggcttagcaa tttctgtaag
    16441 gttaagggcg atgttgtttt tgttataaga tgtgtgttgt gctgctttca tgttcttctc
    16501 ttttctatta tatcatttgt tcctgtatca cttacaggtc tatgtttgag tttataaaat
    16561 ctgaccgagg tcagattcgg gttacttgtg cggattgata gagattagta atcacattat
    16621 ctaaggattg acgactgagt tgattttcca gttcttgttc aacgctggaa aagatgggaa
    16681 ccattgcgcc ttctatatgc tgcccaaccg gacaagaaag attggcattc tggtgtatct
    16741 gaaataggcg aatatgctcc acttcttgcg tcgcaaggta gatttccaat aagctaatat
    16801 ccttaggaga cttgctcaat tggtagcctg aacggccttg gtgcgaagtg attaagcctg
    16861 catttttcaa aagtgcaatc accttgcgga tgtagctggc attggtgcca acgctctcag
    16921 ctaaggcttg cgagctaagt atttccttac tctcactgat catggtcagt atatgaaggg
    16981 ctactgaaaa ctttgtatcc atctggtttc ctttctgttc ttgtatcatt tacaagaaca
    17041 agtttaccat aagctagact tcttggcaag tcttttgctt tatagtcatt tgaattaact
    17101 ttgatacatc gtcactttcg gcttgccgta ctctgcagaa gtgacttgct ttgcaagtta
    17161 tatctccaac ctagcacagc cactaggctg tgctagcaac ctgcacctcg gttccttgtc
    17221 tgaaagctaa ttcattcgac tatatttttt taacaaagca ttcgaccaag aagtcgcttg
    17281 tcttacatgc gtttgccgtc taggacaaat ggcaaggttt tttctatatg ataagcgtgg
    17341 actgctgagg agtattgcac cacttctgca ttcaactgcg gagcctggtt ggcatagaag
    17401 gcctctcttg ccgcctgatc cgcaaaacct gggatgatgg aggcatgaag atggtcttct
    17461 ttaggattgt catgggcaac atttggggta ttccaagtcg ctttattcca aggaagatag
    17521 acctgtgttc gtacttccgt taccccagag attgtcgcca gttgactggc gagtccatct
    17581 tgaacaaatt ttttgaagct accgctcttc accccatctt tgcgacggaa gtataggaca
    17641 tcacgcagtt gggtttgggc ctgagtgcta gtatggtacc aacgtgatga ataagggaag
    17701 cccatgtgca tcaaagtccg acggaaaaca ttgacctcat cttcaaaggc cagggccgtc
    17761 tgacggcgac cgcctattgg tgccaataac ttttgatagg tcacttccgc aatgccatca
    17821 atccgacgat cttctggaac agccgtttcc aagcctgtcg ctttcggcca aaaactatgt
    17881 tctgtctcac tcaaatgttg ctggcggtat tctaatagac ccggtgaagc tgcaataatc
    17941 tgtgcatgcc cgccactcca gtagtccatt ccctcttggc gtgctttatc ctgacgcatc
    18001 cataataaaa tggacagtga aaatcgttgt tggtatcctt ttgtcatgtc ttctcctttt
    18061 gttcttgtat catttacaga aacaagttta tcaaaagcca gacttttttg gcaaggattt
    18121 ggctcaaaag ataaaaaaag taactctctt actagtcgaa agttacttcc tgatactcaa
    18181 tgaaaatcaa aagtagccta ggaaacgaag gtgaagattg aacaggagtt cttcaaggca
    18241 agttgacaac ggaacatttt gattttcgaa gagtatgagt ttcaactatt tttctgttac
    18301 tacttaccta aaactctcac tatatttcat ctggctcttg gccatcatgg gcctgccatt
    18361 tgcagtcgct caattccata ttggtaaagc gagctgtaaa actggagttt tctggtgaac
    18421 aggcatatag cccaaaagct attttccccg ccccttgatg aaaatggcaa acccgcattt
    18481 gtttgaagtg gataccatct tcggaatttt caaaacagta atcagctccc ctgcgactga
    18541 gcctaaacca catggatttg atttgtgaac tgacttcagt agttgcccag tcagaaaagc
    18601 cgtgattagt caccacactt cccaagtgtt ggaagtcatc attttcatac tctatcgaac
    18661 atttgagcca attctccgaa tcttgataaa ggacaattcc acactggtca aatcgagtat
    18721 gactacccgc aaaatccgtc ttcacagtaa aagaaaaata gtcctcctct gtctccatct
    18781 gtaagacagg agcattgtca ttcacaaaat ggtaataggt cttctgccac aaatccgtct
    18841 gggggtgggt ggtaatggta acttcttcat ctgaaatagt gaattgtctc ggtggacggg
    18901 tccacactaa atccttaacc gtaaattctt tcattatgaa cctttccgta tctcatcttc
    18961 ctgataggct gctcggactc cgccgattag ttttggtcgg ctggcgagag ctgtgacatg
    19021 ggcctgtcca atttcacgca ggctaggtct aatcggaact tggacgtgct tgatgtgcat
    19081 gccgatagct gtgtcgccga tgtctacacc agcctgagcg gtgataaact cgacttccac
    19141 cgggtccttc atatacttga aggccgccag ctgtcctgaa ccacctgcat gaagggtggg
    19201 taagacattg actatttcca agtccttctg gattgctaat tcacgctcca ccaccaaggc
    19261 acgattgagg tgttcacagc cttggacagc tagatagata cctttttgat ccagaatttc
    19321 caagatggtt tcaacaacca cctcaccaac ttccagactg gaatttttcc cgatatgccc
    19381 tccaatcacc tcactagagg acaatccaag gacaaatatc tgtccttttt gaagatcgct
    19441 gagttctagg acttcttgca caacttgctt agtttggtct ttaatttccc ttaataacat
    19501 gatttactgc accaattctt tctattgcct gagccaagac gtaaccaact accaaaccaa
    19561 ctgtgttttg caaggtattg cttagaacac tttcaatggc tttcaggtca ttaaaataaa
    19621 gtcgagatgc caggtagtag cccccaacca tagagagggt cgccaagact aaaccgagaa
    19681 tccgtttctt acctgtccaa cccgcaaaat aaccctgagc cccgtggaat actagactaa
    19741 agaatgccca ctggggatag cccaacaaga aatcaatcag aagccctgac aatccgccga
    19801 caatggctcc ctctttcttg cccaagtaaa aggctgtaaa atatacccca acatccaaga
    19861 gtgtgacaaa accagttgca gttggtacat gaacaaaggc taataccaaa ctcaaggctg
    19921 ttaagatagc gagcaagacc aattcttgcg tttgtttatt tctcatattg aaccacccca
    19981 taatcatctg atttttcaat cgccgcatgg acaaagtcct tggacagcct gaccgcctcc
    20041 aaaggctctt gacccagcaa aagctgactg gcaatgctgg acgcaaaggt acagcctgcc
    20101 cccacattgt tttctgacag cagaggcgac tggagcacca ccacttcctg accgtcgtag
    20161 aaaacatcaa ccgcctctga gccacccaga cgattgcctc ccttgatgac caccgccttg
    20221 gctcccaagt catacaagac cactgccacc tgcttcatct cttccaccgt tttgatatcc
    20281 ttttggagca atagctgagc ttctgccaga tttggcgtga taatgctgac ataaggaagg
    20341 aatttcaaga tttcatctcg caactgactg acctcggtat cgtgcgtttc cttgcagacc
    20401 aagactggat ccaagaccac aggaatctcc tggtgagtct tgataaactc caaagcctgc
    20461 tctgctattt ccacagaggg aagcaagcca atcttaatcg cagaaaaggg cacatccttc
    20521 aaactagcca gctgctgggc aaagaccgca gtctccgtcg gaatgacctc aaaacctttt
    20581 tccgtcatag ctgtcaagca ggtcaccgcc acaaagccat gcagcccatg gactgtgtag
    20641 gtggtcagat ctgcgtggag cccgccaccg ctgaaaatat cgttgccaga aagcgccaaa
    20701 atatacttag tcttcataga taatctcctt tagatagagg ccgttgcctg ccgcagtcgg
    20761 acccgccaaa ccacgatcct tttctgctaa aatcctttta atctgcccaa caggcatgcg
    20821 accattgcca attttcaaga gggtcccgac catattccgc acctgcttgt acaaaaaacc
    20881 gttgcccgaa aaggtgaaaa tcaagaactg ccgctgctgg tcatattcca tacttgctac
    20941 tgtaatggtc cgcaccttgt cctcgaccga ggtccccgaa gccgtaaagc ctgtgaaatc
    21001 atgggttccc actaggtcct gaatggcttc ttctatcaag ctcaagtcca aatcataggg
    21061 atagaaggtc gcatagtggc gcatcatggg attcttaggt cgcccaatat ccaccagaaa
    21121 ctcataggtc ttgctgtgct tggcatagcg gcaatgaaaa tcatccgcca cctgctccac
    21181 actgaccaca tcaatatcct cagaggtttg ggtatccagg gcaaagcgga gcttctccac
    21241 atctcgactg ccagccaagt caaagtgtat aacctgaccg taagcgtgga cccccgcatc
    21301 tgtacgacct gcaccatgaa cggttactgg ctgaccacta ttcaatctta ctaacgtttt
    21361 ttcgatttct tcctgaaccg tacgagcatg gggctggcgc tgaaaaccag aaaagtcatg
    21421 tccgtcgtag gaaataattg ccttatatct tgtcatgttt tgattgtagc acaggaaaag
    21481 tatgtaaaca agtcatgaga caccaaactg tactatgaca gatttcctgt ctcaaaattg
    21541 acacaacctc ccaaatacac tataatgaaa ctgaatattg tatcttagaa tttttataaa
    21601 ataataacga aaggaggaaa ctatggaact ccattctcac ttcaatgcag aaaaccaaac
    21661 tgcttttgaa cacgtcatcc aacatctaaa agaaaagggt atacgcatta ccgaaactag
    21721 aaaagcagtc gttgcctaca ttatcgaaag cgatgaccac cctagtgctg aaatgattta
    21781 tcaagatcta atacctaact accccaacat gagtctggcg actgtttaca acaacctcaa
    21841 acttctattg gaagaagggt tcgtgaccaa attgaaacgg accaatgata atactactta
    21901 ttacgacttt atggggcacg agcacctcaa tgttatttgt gaagtctgtg gaaaaatcac
    21961 tgatttcatg gatgtagaaa tcccgagctt gaagaaggaa gctcataccc aaactggtta
    22021 caaaattaca aaagaggtgc tatccatcta cggcatttgt cctgattgcc agaactaaaa
    22081 gacgaatatc aaagcggctt tctgtcgctt
//
LOCUS       DBNFCO010000031        21956 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.031, whole genome shotgun sequence.
ACCESSION   DBNFCO010000031 DBNFCO010000000
VERSION     DBNFCO010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 21956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21956
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.031"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            191..3100
                     /locus_tag="AC1PIV_000988"
     CDS             191..3100
                     /locus_tag="AC1PIV_000988"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 3 protein"
                     /protein_id="HIP6612020.1"
                     /translation="MKTWKRKGALLSLAGALLSGKIVYADSYPSSYQSLDAVGIAKTV
                     FICSAVVVLGLLGFAIYRVVKEKSLSSKKKKLGFGLLALLSIIIVGANYAVNMFVNVI
                     DTYFAPSYADAAKIADAEEVSKSLVTTIQEEGTVLLENKNKTLPLEKSSKVNVFGISS
                     VAITYGGSGSGAADESKNINLQQGLENAGFEVNSELTDFYTENLPEKEGTNIFSLNGG
                     DYNIYEPTQDKYSEELLTNAKNFSDTALVVISRNGGEGADLPQNMAEYQQGDKDKHYL
                     ELQEVEKAMLKTVTENFDKVVVLVNSSNAMELGFLEDAGVDAALWIGGPGSTGLTGVA
                     NILAGEVNPSGRLVDTYAYDLESNPTYWNTGDFSYTNITYEKTPWGAKEPQTFNYKFV
                     NYQEGIYLGYRYYETRFVDNATGQVDEAAYDKVVQYPFGYGLSYTNFDQEITSMKENG
                     DKIEVNVKVTNTGDVAGKEVAQVYYTAPYTEGGVEKSHVVLAGFDKTEVLEPGKSEEL
                     TISFDRDDMASYDEKTEKAYVLDKGDYEIKLMNNAHDVLDSETYTVDSKEVLKQRSSD
                     KAEVTNAFEYAVGDINYVTRADWDGTLPTERTKDKEASEQIATEINNANFRIDESSET
                     PIDTVTTEDNGLRLVDLIGANYDDERWEQLVAQMSVDEMVNLVGFGGYATGAVKSIDK
                     PAVVDLDGPAGINGIFQGIKGIQYNSEVVVASTWNTDLAEEMGDAFAKEALAHGIVGL
                     YAPAVNIHRSPFSGRNFEYYSEDPLISGKMASSLVAKALENGVYTFTKHFALNDQEDN
                     REGVATWSNEQAMREIYLKAFEIPVKEGGATAIMSSFNRIGTLWAGGNSDLLNTVLRD
                     EWGFRGMVITDFDGQDYMSPDQAIRNGGDLMLTPVGDAPTATSTGTKEGVAALRQASK
                     NILYTVAHSAAFDIYKPKTKWWIVVLVASNIALIGLTGLGLVKLTGKKKEEKEVA"
     gene            3139..3618
                     /locus_tag="AC1PIV_000989"
     CDS             3139..3618
                     /locus_tag="AC1PIV_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HIP6612021.1"
                     /translation="MKEWIAKHPDLWEFIKFNVLSNIATITNFCVLWLSTNFLFTALS
                     SQPFHWFIFHYSVENGGLNGFLSFLLAYIAAQVVNYIVQRKLVFGAENDISKTLHWYI
                     LTVVVAGILSIVLPPYTTQLFTSWGLSLGWAQTAANWVNIFVQVAVNYPMMKFVIMK"
     gene            3980..6379
                     /locus_tag="AC1PIV_000990"
     CDS             3980..6379
                     /locus_tag="AC1PIV_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 3 C-terminal
                     domain-containing protein"
                     /protein_id="HIP6612022.1"
                     /translation="MKYQEIINRLTLEEKAALMSGKSVWETKDYPEKGIPSIFLSDGP
                     HGIRKQEGEGDHLGLNASVPATCFPTAATLANSWDVDLVERVGQGLGAEANSLGVNVI
                     LGPGLNIKRSPLCGRNFEYYSEDPYQAGKLAAAMIRGMQSQGVAATPKHLAVNSQELR
                     RMASDSIVDERTLRELYLTGFEIAVREGNPKAIMSAYNKINGVYANEDKHLLRDILRD
                     EWGFTGFVVSDWGGSNDHVLGVENGSHLEMPGTKKVGQKEIIHAVQSGRLSEQVLNER
                     VDELIDVVLELAHAEKQSVDYSEQHELARQAATESIVLLKNKDQILPLSSETKIALIG
                     EFAQNPRYQGAGSSLINTRQLDKTVDCIADYPLNVIDYEQGYQRVDKENRVLVDRAVN
                     LANQAELVLYYMGLDEMSESEGLDRHHISLPKNQLSLLNALVGTGKKIVVVLSAGSVV
                     DMNWDVDVDAVLHGYLSGEAGARAILDTLTGRVNPSGKLSETYPINLADVPSSDDYPA
                     EGDFSLYKEALYVGYRYFTSLDKTVKYPFGYGLSYTDFSYSQLDVTELGVRVTITNTG
                     LVDGAEIVQLYVGKEVRQIYRPAKELKGFKKVYVKAGESKQIFIPFEDYTFRYFNKET
                     GQFEVEAGNYLLYVGASSQDIRLVGEITREGTVDQFPASEQIPTYLTAQVQAVSEQDF
                     AQLLGRPVPEETWKIGQELSLNDPVLKLQFAKSGLARGVHKLLAGLLKKAEQKGTPDL
                     NLLFLYNMPFRAMAKMTGDMLDLPMVEGILTIVNGNFFKGLGQLWRAYQAKRKYQKQL
                     S"
     gene            6424..7437
                     /locus_tag="AC1PIV_000991"
     CDS             6424..7437
                     /locus_tag="AC1PIV_000991"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HIP6612023.1"
                     /translation="MTLLSIAIPSYNSEAYLHYCVHSLVMGGDKVEILIINDGSTDRT
                     QEIAEGLENQFSNVRAIYQDNKGHGGAVNTGIREAKGKYFKVVDSDDWVDTRAYLKIL
                     ESLQALEDENTPVDAFISNFVYEKEGQSRKKSMSYQDVLPENRIFGWEDVDAFSKGQY
                     MMMHSLIYRTDLLREVGLVLPEHTFYVDNIFVFTPLQAVKTMFYLPVDFYRYFIGRND
                     QSVNESVMIKRIDQQLKVNRILVDNLDLEAIDNPDLRSYLLNHVEITTIISCALLNRA
                     GTAEHMMKKQELWHYIRDNNPALFKIVRKGLLGQLTNLYGYPGRKISNAVYKIAKRIY
                     GFN"
     gene            7507..8418
                     /locus_tag="AC1PIV_000992"
     CDS             7507..8418
                     /locus_tag="AC1PIV_000992"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HIP6612024.1"
                     /translation="MQRLGQTGLEVSRIALGCMRMASLREKETAKVLETVVEQRINFF
                     DHADIYGGGESEIRFAQGAKLAGLKREDMLLQSKCGIRKGYFDFSKEYILESVDGILK
                     RLDTEYLDVLVLHRPDALMEAEEVAEAFYLLKKAGKVHHFGVSNQNIYQMELLQSYLD
                     QPLAVNQLQLSPAHTPLIDAGLHVNMKDDAATMRDGGLIDYCQLKKITIQAWSPFLID
                     LQRGIFANYPDYAHLNQTIEEIAERYNVSHETIVVAWILRHPAKIQTIVGSMNPGRLT
                     KIAQASQITLTRPEWYEIYRSAGNILP"
     gene            8428..8880
                     /locus_tag="AC1PIV_000993"
     CDS             8428..8880
                     /locus_tag="AC1PIV_000993"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIP6612025.1"
                     /translation="MKWEIKTFEQLSLHELYTILTLRTDVFVVEQACPYPEIDGKDPS
                     CLHLLGTDNGELVAYLRILPAGLSYDEVSIGRVVIKPSHRGKGLGRPMMEQAIHYITT
                     EWKESQIKIGAQAYLEKFYQSLGFKPVSEVYLEDDIPHLDMLYSKPVN"
     gene            8975..10726
                     /gene="aspS"
                     /locus_tag="AC1PIV_000994"
     CDS             8975..10726
                     /gene="aspS"
                     /locus_tag="AC1PIV_000994"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HIP6612026.1"
                     /translation="MKRSMYAGRVRKEHVGQEITLKGWVGRRRGLGGLIFIDLRDREG
                     IMQLVINPESVEAEVMAKAESLRSEFVIEVTGTVVEREQANDNIPTGAVELQVTSLTV
                     LNTAKTTPFEIKDGIEASDDTRLRYRYLDLRRPEMLNNFKLRAAVTHSIRNYLDDLEF
                     IDVETPMLTKSTPEGARDYLVPSRVSKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLNEVEIQDIVEGLIAKVLKDTKGIDVTLPFPRMAY
                     DHAMNFYGSDKPDTRFEMLLQDLTELVKEVDFKVFSEAPVVKAIVVKGAADSYSRKDI
                     DKLTDYAKQFGAKGLAWVKVDKGELAGPVAKFLTGITEKLTASLQLEDKDLVLFVADE
                     LEVANNTLGALRNRLAKEQGLIDESKFNFLWIVDWPMFEWSEEEGRYMSAHHPFTLPT
                     EETAHHLDGDLAQVRAVAYDIVLNGYELGGGSLRINQKDMQEQMFKALGFSAEDAHEQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEDNIREVIAFPKNNKASDPMTQAPSTV
                     ASAQLEELALDITLENE"
     gene            10713..11651
                     /locus_tag="AC1PIV_000995"
     CDS             10713..11651
                     /locus_tag="AC1PIV_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002265645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HIP6612027.1"
                     /translation="MKMNKFFRKQRVRFLRKARKNKFWSVILGISREKYAERISGSII
                     YGLLSSIAVNFFFRPGNVYSSGVTGLAQIVSALAASYAGWNVPIAVVYYGLNIPLLIL
                     AWYKIGYKFTIFTFITVSFSSFFIQFMPPVTLTTDPLVNAIFGGLMLGTGIGFALRNN
                     VSSGGTDIVSIIIRKKTGRQVGSISLIVNIMIMLIAGMTFGWQYALYSMVALFISSRM
                     TDAIFVKQKRMQAMIITNHPERVIKKIHKKLNRGVTIINGAEGAYNHEQKTILITIIT
                     RAEFNDFKHIMKKADPKAFVSVADNVNIIGRFVESD"
     gene            11728..12180
                     /gene="nrdI"
                     /locus_tag="AC1PIV_000996"
     CDS             11728..12180
                     /gene="nrdI"
                     /locus_tag="AC1PIV_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002941880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HIP6612028.1"
                     /translation="MKKKIYLVYISLSGNTESFVKRLKSFFQFQTDWEIELVHVKDLV
                     KQAIPFYQLDAPFVAFLPTYLEGGNGVDNGDVEILTNPLGDFIALGTNAELCLGVVGS
                     GNRNFNNQYCLTAKQYAERFNFPVIDTFELRGMQNDIERIGRKIMELM"
     gene            complement(12334..14385)
                     /gene="pulA"
                     /locus_tag="AC1PIV_000997"
     CDS             complement(12334..14385)
                     /gene="pulA"
                     /locus_tag="AC1PIV_000997"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015445376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051060 - pullulanase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HIP6612029.1"
                     /translation="MALRQFQASLDDVATIRLVMKKRFDSEHMSFSLESNDATSQLFI
                     HSCLEVDNLVIYYLTSLHALTLDKDYTIYDQDRNKTELGYGHIVRSTLFEQSYTYNGQ
                     DLGATYRPEATTFKLWAPISKQVFLVLEGNPHAMTKGAKGVWEITVEGDLEAHSYHYL
                     HKVNGEWISVHDPYALSSTANSGDSYVINPDKLHKIRRAKTQRPISQAIIYEMSVRDF
                     SWQKEAGFKHRSQFLGLTESPTMDGMKLGMDYIRELGVTHIQLLPVYDFGSVDENKPQ
                     AVYNWGYDPMQYNLPEGSYSSQPNDPYARILELQEAIQAYHDADISVIMDVVYNHVYH
                     AEKYAFELIVPGYFYRYDDHGMRTDGTFCGNDVASERSMVRNYIKQSLRQWLELYGFD
                     GFRFDLMGILDSETINQIQTELSAIHPNVYLYGEGWKMATGLEFEKLAHQYNAEHLPE
                     ISFFNDDYRDTFKKLLLNPNRLIDKQLHEKVQHLLTGSRLSHFLTPQQSLNYIECHDN
                     ATAFDYFHIENPNWTPQQQKRAASFGLQLILISQGMAFIHSGQEFFRTKDEIDNTYNI
                     PDRINRLDWTRAIRYKEHIEFIQELITFRKNNPILSQDNYESIQETCDFYWLTEYVLR
                     YQVTSEEKTIQFIINFADSDFTYEREKDKAVLYNYPPVEERDQQEITIAGQSICILED
                     K"
     gene            complement(14409..15392)
                     /locus_tag="AC1PIV_000998"
     CDS             complement(14409..15392)
                     /locus_tag="AC1PIV_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002941885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HIP6612030.1"
                     /translation="MRATIKDVAKLAGVSPSTVTRVIQNSSAISQKTKDLVRKAMADL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDVFYQNPFFPTALRGISQVAADHNYAIQIST
                     GKNEEQRLEAISQMVYGKRVDGLIFLYSKPDDPLVQLAIQHKFPFLILGKADSPFISL
                     VDNDNIQAGFEATNYFINKGYKNIAFVAGNKELVVSQDRYTGYKNALKSHNIPLDENK
                     VKFVSGFLLEDSAYKISKKLLKQDLDAIVTTDTSVAEGVVKYLNEVGVKLPIISFDSV
                     KPKLDIEAYVDVHAIKLGRVAFNTLHQIINDNKEDKQVCYRRVIPHTITEL"
     gene            complement(15402..16112)
                     /locus_tag="AC1PIV_000999"
     CDS             complement(15402..16112)
                     /locus_tag="AC1PIV_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612031.1"
                     /translation="MNLWQRLFTTLFLVALLLIPSSLQTVNLETYPLENFVEGIYAPL
                     TDQVVDDLRQHAVIENNHLTYTGNTNWEQVTFGDTVSSSSDFTYQFANQSLTIRKGSD
                     ILSELTYEGLNTDDFASKETLTATISKKWYQANRAAVGLSITLISTFILTTNLLFILL
                     GASFFLFLTKKSRFFHFETFAECYNFALNCLGLPTLIACLIGLFGQPVTTLLTIQNIL
                     FVLCLLWVFFKTKFRDEI"
     gene            complement(16244..17086)
                     /locus_tag="AC1PIV_001000"
     CDS             complement(16244..17086)
                     /locus_tag="AC1PIV_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002941891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HIP6612032.1"
                     /translation="MKVSVKTRRILNQTLTYLYLIVLSVIIIYPLLITIMSAFKSGNV
                     VAFKLDSNINFTLDNFSKLFSETLYGTWYFNTLIIALLTMVIQTSIVVLAGYAYSRYN
                     FIARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNQSWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPISLDESAKLDGAGHFRRFWQIVLPLVRPMIAVQALWAFMGPFGDYILSKF
                     LLREKEFYTVAVGLQTFISDVKNMKIAYFAAGAILIALPISILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(17088..18383)
                     /locus_tag="AC1PIV_001001"
     CDS             complement(17088..18383)
                     /locus_tag="AC1PIV_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003027817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HIP6612033.1"
                     /translation="MTMKQNPGKALLLSLIPGLGQIYNKQKAKGYIFLGVTLAFLVYF
                     IAIAAGELGNLITLGSVRGQDNSLFMLIRGSFHLIITVVYLAFYALNLKDARDTAKRW
                     NSRMPVATTLKEMVKGIYENGFPYLLIIPSYIAMTFAIIFPVVVTLFIAFTNYDFKHL
                     PPSALLDWIGITNFTNIWKLSTFRTAFGSVLGWTIIWALCASTAQIVIGILTAIIANQ
                     PFIKGKRIFGVIFLLPWAVPAFVTILTFSNMFNDSVGAINTQVLPFLSKFLPFIDNFL
                     IPWKTDPFWTKVALIMMQAWLGFPYIYVLTLGILQSIPNDLYEAAYIDGASAIQKFRN
                     ITLPMILAVAAPTLISQYTFNFNNFSIIYLFNNGGPGSVGGGAGSTDILISWIYKLTT
                     GTSPQYSMAAAVTLIISMIVISISMIAFKKLNAFEMEDV"
     gene            complement(18596..19855)
                     /locus_tag="AC1PIV_001002"
     CDS             complement(18596..19855)
                     /locus_tag="AC1PIV_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002941908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HIP6612034.1"
                     /translation="MKHNLLKSVALLAASTAVLAACSNSGSSTEASKSAEGSKELTVY
                     VDQGYESYINDVKAGFEKENGVSVTVKTGDALTGLDNLSLDNQSGSAPDVMMAPYDRV
                     GSLGSEGQLSELTLADDSKADDTTTALVTNGGKVYGSPAVIETLVLYYNKDLLTEAPK
                     TFAELETLAKDSKYAFAGEEGKTSAFLADWTNFYYTYGLLSGYGGYVFGENGTNPKDI
                     GLANEGAIKAIEYAKTWYEKWPQGLQDGTAANNLINTQFTDGKAAAIIEGPWKAASYK
                     EAGVNYGVATIPTLVNGKNYSAFGGGKAWVVPAGAKNQEMAQKFVDFLTATDQQKALY
                     DATNEVPANTEAREYAVSKKDELTTAVINQFASAQPMPNISEMGSVWTPAGNMLFEAA
                     SGSKDAKTAATDAVKAIADEIAQKHSN"
     gene            20158..21675
                     /gene="malQ"
                     /locus_tag="AC1PIV_001003"
     CDS             20158..21675
                     /gene="malQ"
                     /locus_tag="AC1PIV_001003"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004134 - 4-alpha-glucanotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005980 - glycogen catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HIP6612035.1"
                     /translation="MKVRQSGVLMHISSLPGKYGIGSMGQSAYEFVDFLVRTKQRYWQ
                     ILPLGTTSYGDSPYQSFSAFAGNTHFIDFDILIDKGWLAAEDLHGVDFGQNPTEVDYA
                     AIFYARRPLLEKVVANMKAQGLPEDYWMFLGENDFWIHTFAEYMAIKEHFDLKPWTEW
                     EDQGARLRYHDTLEYYRHLLADRIDYHRITQYLFFSQWKALKAYANAKGVEFVGDMPI
                     YIAADSADMWANPHFFKTDEEGKPSVVAGCPPDAFSEIGQLWGNPIYDWEAMKHDGFT
                     WWVARLRESFKIYDMVRIDHFIGFASFWEIPAGEETAVNGYRVEAPGFELFDTIKREL
                     GDLNIIAEDLGSVTDKVIQLRDTTGFPGMKVLQFAFDPEGDSIEMPHNHPNNVVAYTG
                     THDNDTILGWYENETTKESRAFLDKYSNRREGETVSHALFRLLFGSPAFMAVATMQDL
                     LGLDGSARMNLPNTLGGNWTWRMTADQLTPEIEAELLDLTETYRRVNVHLVDEKS"
     gene            complement(21718..21900)
                     /locus_tag="AC1PIV_001004"
     CDS             complement(21718..21900)
                     /locus_tag="AC1PIV_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612036.1"
                     /translation="MKKLPTYIGVIIFVVTLLINWLLPSLAKVLNTFFIWTIVACLLY
                     TIYYWIRYWLYVLQQR"
BASE COUNT         6412 a         4072 c         5094 g         6378 t
ORIGIN      
        1 tgttagctat attttagaaa atcaaatgat aaaatagcaa gagtaggatt attcttataa
       61 atttacaaat tatgaaggtt aaatgacaga ttatgaagaa agggttttca ttgagtatgt
      121 taattgatat agtggattca agaaaaagaa aaggcttaca tgaaagccga aatgtttagg
      181 aggaagtctt atgaagactt ggaaaaggaa aggggctctc ttgagcctag caggagctct
      241 gctatcagga aaaatagtct atgcagatag ctatccaagt agctatcaat cattggatgc
      301 ggtcgggatt gcaaaaacag tatttatctg ttctgctgta gttgtccttg gcttattggg
      361 atttgcgatt tatcgcgtag tgaaggaaaa atccctctct agcaagaaga aaaagttggg
      421 ctttggcctc ttggctctct tgagtatcat tatcgttgga gctaactatg ctgtcaatat
      481 gtttgtcaat gtgatcgaca cctattttgc gccgtcttat gcagatgctg ctaaaattgc
      541 tgatgcagaa gaagtttcta agtccttggt aacgaccatt caagaagaag gcactgtctt
      601 gcttgaaaac aagaataaga ccctaccact tgaaaaatca tccaaggtca atgtctttgg
      661 tatttcttct gtagccatta cttacggtgg atctggttca ggtgcggcag atgagtccaa
      721 aaacatcaat ctgcaacaag gtcttgaaaa tgcaggtttt gaagtcaaca gcgaattgac
      781 agacttctac acagaaaacc ttccagaaaa agaagggaca aatattttct ccctcaatgg
      841 tggagattac aatatctacg agccaactca agacaaatac tcagaggaac tgttaacaaa
      901 cgcgaagaac ttttcagata cagccttggt agtcatttct cgtaatggtg gtgaaggtgc
      961 ggaccttcca caaaacatgg cagaatacca acaaggtgac aaggacaagc actaccttga
     1021 acttcaagaa gttgaaaaag ccatgttgaa gactgtgaca gagaactttg acaaggttgt
     1081 tgtcttggtt aactcctcaa atgccatgga actcggcttc ttagaagatg caggcgtcga
     1141 tgctgctctt tggattggtg gtcctggctc aaccggcttg actggtgtag ctaatatctt
     1201 ggcaggggag gtcaacccat ctggtcgctt ggtcgatacc tatgcctacg acttggaaag
     1261 caatccaacc tactggaata caggtgactt ctcttatact aatatcacct atgaaaaaac
     1321 tccatgggga gcaaaagaac cacaaacctt taactacaaa tttgttaact atcaagaagg
     1381 tatctatcta ggctatcgtt actacgaaac tcgctttgtt gacaatgcga ctggtcaagt
     1441 ggacgaagca gcttatgata aagttgttca atacccattt ggttacggtt tgagctatac
     1501 caactttgac caagaaatca ctagcatgaa agaaaatggt gacaagattg aggtcaatgt
     1561 taaagtaacc aatactggtg acgtggctgg taaggaagtt gcacaagtct attacacagc
     1621 tccatatact gaaggtggtg ttgagaaatc acacgttgtc ttggctggat ttgataagac
     1681 tgaggtcctt gagccaggta agagcgaaga attaaccatt tccttcgacc gtgatgatat
     1741 ggcatcttac gacgaaaaga cagaaaaagc ctatgttttg gacaagggtg actatgaaat
     1801 caaactcatg aacaatgcgc atgatgtctt ggattcagaa acctacacag ttgatagcaa
     1861 agaagtcttg aaacaacgtt catctgataa ggctgaagta accaacgcct ttgaatatgc
     1921 tgtgggcgat atcaactatg taacccgtgc ggattgggac ggtactttgc caaccgaacg
     1981 cacaaaagac aaagaagcaa gtgagcaaat tgctacagaa attaacaacg caaacttccg
     2041 cattgacgaa tcatctgaaa caccgattga tactgtgaca acagaagaca atggacttcg
     2101 tttggttgat ttgattggtg caaactatga tgatgagcgt tgggaacaac tagttgctca
     2161 aatgtctgtt gatgaaatgg tcaacttggt tggctttggt ggttatgcaa caggagcagt
     2221 caaatcaatc gataaaccag ctgttgttga cttggacgga cctgctggta tcaacggtat
     2281 cttccaaggt atcaaaggta tccaatacaa ctcagaagtc gttgttgctt ctacttggaa
     2341 taccgacttg gcggaagaaa tgggtgatgc ttttgctaaa gaggcattgg cacacggtat
     2401 tgttggtcta tatgctcctg cagtgaacat ccaccgctca ccattctcag gccggaactt
     2461 cgagtactat tcagaagacc cactgatttc aggtaaaatg gcaagctcac tggtagcaaa
     2521 agctcttgaa aatggtgtct atacttttac caaacacttt gctctcaatg accaagaaga
     2581 taaccgagaa ggtgttgcaa catggtcaaa tgaacaggca atgcgtgaaa tctatctgaa
     2641 agcctttgaa attcctgtca aagaaggcgg agcgactgct attatgtcat cctttaaccg
     2701 tattggtacc ctctgggcag ggggtaatag cgacctcttg aatacagttc tccgtgacga
     2761 gtggggcttc agaggaatgg ttattacgga ctttgacggt caagactaca tgagtccaga
     2821 tcaagcaatc cgcaatggtg gcgaccttat gttaacccca gtaggtgatg caccgacagc
     2881 aacctcaaca ggtactaaag aaggtgttgc agcacttcgt caggcaagta agaacatctt
     2941 gtacaccgtt gctcattctg cagcctttga catctataaa ccaaaaacaa aatggtggat
     3001 tgttgtattg gtagcaagta atattgccct tatcggcttg acaggtcttg gactcgttaa
     3061 gttgacaggt aagaaaaaag aagaaaaaga agtagcataa caagggggat ttcccccttg
     3121 tcttgcatag gagaccgtat gaaagaatgg attgccaaac acccagattt gtgggagttt
     3181 atcaagttta atgtcttatc aaacatcgca actattacaa acttctgcgt cctttggttg
     3241 tcaaccaatt tcctctttac agccttgtca agtcagccat ttcactggtt tatctttcat
     3301 tattccgtag aaaatggcgg attgaacggc tttctctcct tcctcttggc ttacatagcg
     3361 gcacaggttg tcaactatat tgttcaaagg aagttggtat tcggagcaga aaacgatata
     3421 tccaaaaccc tccattggta tatcttgact gttgtcgttg caggaatttt gtccattgtg
     3481 ctgccgcctt acaccactca actctttaca tcatggggct tgagcttggg ctgggcacag
     3541 acagcagcca actgggtcaa tattttcgtt caagtggctg tcaactatcc aatgatgaag
     3601 tttgtaatca tgaaataata ctcttcgaaa atcaaactca gccgttgttg gcttgatttg
     3661 atgagtggaa agttccagtg gaggtttcca gcctgtcgct tgacaataat aaagcgacag
     3721 agttctatct gctcatatag aaacgaacta ggttcgtcct atctcccacc tccaacagtc
     3781 tattctcaga ctgttggagc tagcctgatt ttgattttca ttgagtataa gaagtaatag
     3841 gagcgatctc cctagtattt tctggggaga ttttttatag cagattatgt ccaaaatcat
     3901 acagattatg aagaaagcgt tttaattgtc cctttagtct gatatgatag tgataaagaa
     3961 atagaatgag gaaaagatga tgaagtatca ggagattatt aatcgtttaa cattggaaga
     4021 aaaagcagct ctcatgtcag gaaaatctgt ttgggaaaca aaggattacc ctgaaaaagg
     4081 aattccatct atctttttgt ctgatggacc acatggaatt cgcaagcaag aaggtgaagg
     4141 tgatcactta gggctgaatg cctctgtccc tgcaacttgt ttcccaacag ctgctacctt
     4201 ggcaaattct tgggatgtgg acctggttga acgtgtcgga cagggtcttg gcgcagaagc
     4261 aaatagcttg ggtgtcaatg tcattttggg gccggggctt aatatcaagc gcagtccctt
     4321 atgtggtcga aactttgagt attattcaga ggatccatat caagcgggaa aactggcggc
     4381 cgcaatgatc cgaggaatgc agtcgcaagg tgttgcggca acgccaaagc atttagctgt
     4441 aaacagtcag gaattgcgcc gtatggcttc agactccatt gtagatgagc gtacactgag
     4501 agagctatat ctgacaggat ttgagattgc agtgcgtgaa ggaaatccaa aggcaatcat
     4561 gtctgcctat aacaaaataa acggcgtcta cgctaatgaa gacaagcacc tcttacgtga
     4621 cattctccgt gatgaatggg gctttacagg ctttgtcgta tcggattggg gtggctccaa
     4681 tgaccatgtt ctcggtgttg aaaatggtag tcatttggaa atgccaggta ctaaaaaggt
     4741 tggtcaaaag gaaatcattc acgctgttca gtctggtcgt ctatccgagc aagtattgaa
     4801 tgagcgcgtg gatgagctga ttgatgtagt tttagagttg gctcatgctg aaaaacaatc
     4861 tgtagattat tctgaacaac atgaattggc ccgtcaggct gccactgaga gcattgtgct
     4921 attaaaaaat aaggatcaga tcttgccctt atctagtgag acaaaaatag ctctcatcgg
     4981 agaatttgcc caaaatcctc gctatcaggg agcaggttct tctttaatca atacaagaca
     5041 attagataaa acagtggatt gcatcgcaga ttatccatta aatgtcattg attacgaaca
     5101 aggctatcaa cgtgtagata aagaaaacag ggtgttagtt gacagggctg tcaatcttgc
     5161 aaaccaagcg gaacttgttc tttactatat ggggctagat gaaatgagtg aaagtgaggg
     5221 cttggatcgt catcatataa gtctccctaa aaaccagtta tccttactga atgccttggt
     5281 agggacaggt aaaaaaatcg ttgttgtcct atcagcaggc tcagttgtgg atatgaattg
     5341 ggatgtggat gtagatgcgg ttcttcacgg ctatctatca ggagaagctg gtgccagagc
     5401 cattttagat accttgacag gacgtgtcaa cccatcagga aaactaagcg aaacctatcc
     5461 tattaatctt gcagatgttc catcttcgga tgactatcca gcggaaggcg atttttccct
     5521 ctataaggaa gctctctatg taggctaccg ttactttaca agccttgaca agactgtcaa
     5581 gtatcccttt ggttatggat tgtcctacac agacttttct tacagtcaat tggatgtgac
     5641 cgaattagga gtcagagtca ctattacaaa tactggtctg gttgatggtg ctgaaattgt
     5701 ccaattgtac gtaggcaaag aagttcgtca gatttaccgc cctgcaaagg agttaaaagg
     5761 ctttaaaaaa gtatatgtaa aagcaggcga gtccaaacag atttttattc cttttgagga
     5821 ctatacgttt cgttatttta ataaagagac aggccaattt gaagtagagg ctggaaatta
     5881 tctcttgtat gtaggtgcaa gtagtcagga tattcgctta gttggcgaga ttacccgaga
     5941 aggcactgta gaccaatttc ctgcttcaga acagattccg acttatctga cagcccaagt
     6001 gcaggctgtt tcagagcagg attttgcaca attgcttgga cgtccagttc cagaagaaac
     6061 ctggaaaatt ggtcaagaac tgagcctgaa cgatccagtt ttgaaactcc aatttgcgaa
     6121 gagtgggttg gcacgtggcg tgcataaact gttggctggc ttactgaaaa aagcagagca
     6181 gaaagggact cctgacttga acctgctgtt cctttataat atgccattta gggcaatggc
     6241 aaagatgaca ggagacatgc tcgatttacc gatggtggaa gggattctaa ccattgtcaa
     6301 tggaaatttt ttcaagggct taggccaact atggagagcc tatcaagcaa aaagaaaata
     6361 tcaaaagcaa ctttcctgaa aatgtgataa aatagtaaca aattgtgtca aatggagaga
     6421 aagatgacct tactaagcat tgccataccg agctataatt cggaagccta ccttcattac
     6481 tgtgttcatt cccttgtaat gggcggtgac aaggttgaaa ttctgattat taacgacggg
     6541 tcgaccgatc ggactcagga aatcgcagag gggctagaga atcaattttc aaacgtacgt
     6601 gccatttatc aggacaataa gggccatggc ggagctgtta atacagggat acgtgaggcc
     6661 aaggggaagt actttaaagt tgtagattca gatgactggg tcgataccag ggcctatttg
     6721 aagatcctag agagtttgca ggctttggaa gatgaaaata cgccagttga tgcctttatc
     6781 tccaactttg tttacgaaaa agagggacaa tctcgtaaaa aatccatgtc ttatcaggat
     6841 gttttaccag aaaatcggat ttttggctgg gaagatgtgg atgccttttc caaggggcaa
     6901 tacatgatga tgcattcctt gatttacagg acagatttat tgcgtgaggt tggtctcgtt
     6961 ctgccagagc ataccttcta tgtggataat attttcgtat ttactccttt gcaggctgtg
     7021 aaaactatgt tctatctgcc agtagatttt tatcgttact ttattgggcg aaatgaccag
     7081 tctgtcaatg aatccgtcat gattaagcgc attgaccagc agttaaaagt caatcgaatt
     7141 ttggtagata atttagactt ggaggcgatt gacaatcctg atttacgaag ttatttgctc
     7201 aatcatgtgg agattacgac cattatctcc tgtgctcttc tcaatcgtgc tggaacagct
     7261 gaacatatga tgaaaaagca ggaactctgg cactatattc gggataataa tccagctcta
     7321 tttaaaatcg ttcgaaaagg gttactcggg caattaacca acctttacgg ttacccaggt
     7381 cgaaaaattt ccaatgccgt ctataaaatc gcgaaaagaa tttatggttt taactaaaac
     7441 tcagtttcgg ctgagttttt ctgttataat aaggaatatg aaaagcgttt acaaaggaga
     7501 agataaatgc aaagattagg acaaacaggt ctagaagttt cacgaattgc tttaggctgt
     7561 atgcgaatgg caagtttgag agagaaggaa acagccaagg tattggaaac cgtggttgag
     7621 caaagaatca acttttttga tcatgcggat atttatggtg gtggtgaatc agaaatccgt
     7681 tttgctcagg gggcaaaatt ggcgggattg aaacgtgagg acatgctcct ccaatcaaaa
     7741 tgtggtattc gtaaaggcta ttttgatttc tcaaaagagt atattttgga atctgtagat
     7801 ggaattttga agcgcttgga tacggaatat ttagatgttc tcgtcttaca tcgtccggat
     7861 gctctaatgg aagcagagga agtagctgaa gccttttatc tcttgaaaaa agcagggaag
     7921 gttcatcatt ttggcgtcag caaccaaaac atttaccaaa tggagttatt acaatcctat
     7981 ctcgatcaac cgcttgcagt taatcaattg cagctatctc ctgctcacac gcctttgatt
     8041 gatgctggat tacatgtcaa tatgaaagat gatgctgcga ctatgcgtga tggtgggtta
     8101 attgactatt gccagcttaa aaaaatcact atccaagcct ggtctccttt cttgattgat
     8161 ttgcaacgag gtatttttgc caactatcct gactatgctc atttaaatca aactattgag
     8221 gaaatagcag agcgatacaa tgtttcacat gaaacaattg tcgtagcttg gattttgcgt
     8281 catccagcaa agattcaaac gattgtaggt tctatgaatc caggtcgcct gacaaagatt
     8341 gcccaggcta gccagattac cttaacgaga ccagaatggt atgagattta cagaagtgca
     8401 gggaacattc tgccctagga ggaatgtatg aagtgggaaa taaaaacatt tgaacaactt
     8461 agtttacatg aactttacac tatcttgaca cttcggaccg atgtgtttgt cgtggaacaa
     8521 gcctgtccct atccagaaat agatggaaaa gatccaagtt gtcttcatct tttaggaaca
     8581 gacaatgggg agttagtggc ttatttgaga atcttgccag ctggtctaag ttatgatgaa
     8641 gtttccatcg gacgtgtggt catcaagcca agtcatcgtg gcaagggttt aggtaggcca
     8701 atgatggagc aagctatcca ttacattaca accgagtgga aggaaagtca gattaaaatc
     8761 ggtgcccaag cctatttgga aaaattctat caatcgcttg gctttaagcc agtttctgaa
     8821 gtatatttgg aggatgatat tccgcattta gatatgttat atagtaaacc agtcaactag
     8881 ggctggtttt tcgatttttc tcggcaattt ctccccaaaa tcagctattt tatggtagaa
     8941 tgaataggta taaaatcagt aaaagaggaa gaaaatgaaa cgttctatgt acgctggacg
     9001 tgttcgtaaa gaacatgtcg gacaggaaat tactttgaaa ggttgggttg gccgccgtcg
     9061 tggcttgggt ggcctgattt tcattgactt gcgtgaccgt gaaggcatta tgcaattggt
     9121 gattaaccct gagtcagttg aagctgaagt gatggcaaaa gcggagagtc ttcgttccga
     9181 gtttgttatc gaagtaacag gaacggttgt ggagcgtgag caagctaacg acaatatccc
     9241 gacaggagct gttgaactgc aagtaaccag cttgacagtg ttgaacacgg ctaagacaac
     9301 tccgtttgaa atcaaggacg gcattgaagc cagtgatgat acccgtcttc gttaccgtta
     9361 tttggatctt cgccgtccag aaatgctcaa caacttcaaa ttacgtgcgg ctgtaaccca
     9421 cagcattcgc aactacttgg acgatttgga atttatcgat gtggaaacac caatgttgac
     9481 caagtcaaca ccagaaggtg cgcgcgacta cttggtacca tctcgtgtgt ccaaaggtca
     9541 tttctatgct ttgccacaaa gtccacagat tactaagcag cttttaatga acgctggttt
     9601 tgaccgttac taccaaatcg ttaagtgttt ccgtgatgaa gatttgcgtg gggatcgtca
     9661 acctgagttt acacaggttg acttggaaac ctcattcttg aatgaggttg aaatccaaga
     9721 catcgtagaa ggcttgattg ctaaggtctt gaaagatacc aaaggaattg atgtgacctt
     9781 gccattccca cgtatggcct atgaccatgc gatgaacttc tacggttcag ataaaccaga
     9841 tactcgtttt gagatgcttt tgcaagactt gacagaactt gtcaaggaag ttgacttcaa
     9901 ggtcttctca gaagcaccag ttgtcaaagc cattgtggtc aagggtgcgg cggatagcta
     9961 ctcacgtaaa gacattgata aattaacaga ctacgcaaaa caatttggtg ctaagggact
    10021 tgcttgggtt aaagtagaca agggagaatt agcgggccca gttgctaagt tcttgacggg
    10081 tattacagaa aaattgacag caagtttaca gttggaagac aaggatttgg ttctctttgt
    10141 agcagatgaa ttggaagtag ccaacaatac cctgggagcc ttgcgtaacc gcttggcaaa
    10201 agagcaaggc ttgattgatg aaagcaagtt caacttcctc tggattgtgg attggccaat
    10261 gtttgagtgg tctgaagagg aaggtcgcta tatgagtgcc catcacccat tcaccttgcc
    10321 gacggaagaa acagctcatc atttggatgg tgatttggcg caggtgcgtg cagttgccta
    10381 cgatattgtt ttgaatggtt atgaattggg tggcggtagc cttcgtatca accaaaaaga
    10441 catgcaagaa cagatgttca aggctcttgg tttctcagct gaagatgccc atgagcagtt
    10501 tggtttcttg ctagaagcta tggactacgg tttcccacca cacggtggat tggctatcgg
    10561 gttggaccgc tttgtcatgt tattggctgg tgaggataac attcgtgaag ttatcgcctt
    10621 tccgaagaat aacaaggcat ctgatccgat gacacaggca ccaagtacgg ttgcatcagc
    10681 tcaattagag gaattggctt tagacattac acttgaaaat gaataaattt ttcagaaaac
    10741 agcgtgtacg ctttttaaga aaggccagaa agaataagtt ttggtcggtc attttgggaa
    10801 tttctcggga aaaatatgct gaacggatat cggggtccat tatttatgga ctcctatcta
    10861 gtattgcagt caattttttc tttcgaccag ggaatgtcta ttcgtctgga gttactggtc
    10921 ttgcacagat tgtttctgct ctggcagctt cttacgctgg ttggaatgta ccgattgcgg
    10981 tggtctacta cggcctgaac attcccttgc ttatcttagc ttggtataaa attggttata
    11041 aatttactat ctttaccttt attacggtat ccttcagttc tttctttatc caatttatgc
    11101 cgccagttac cctgacgacg gatccgttag tcaatgctat tttcggtggt ctcatgctgg
    11161 gaactgggat tggctttgca cttaggaaca atgtatccag tggtggtact gatattgtct
    11221 ctattattat tcgcaagaag acgggacgac aagtcggctc tatttccttg attgtcaaca
    11281 ttatgattat gttgattgca gggatgacct ttggctggca atatgccctg tattcaatgg
    11341 ttgcgctgtt tatctccagt cgcatgacag atgcgatttt cgtgaaacaa aaacggatgc
    11401 aggccatgat tattaccaat catcctgaac gtgtcattaa gaaaatccat aagaagctca
    11461 atcgcggtgt gaccattatc aacggtgctg agggtgctta taaccatgag caaaagacga
    11521 ttctcattac catcatcact cgtgcggagt ttaatgattt caagcatatt atgaaaaagg
    11581 cagaccccaa agcctttgta tcggtagctg acaacgtcaa tattattggt cggtttgtgg
    11641 aaagcgactg attgacaaac actacatgta ggagtaaaat agtatttaca gtctacatgt
    11701 agtgttttta ttataaagag gaagtgtatg aagaagaaaa tatatttggt ttacatcagt
    11761 ttgagtggca atacagagag ttttgtgaaa cgtctaaagt cctttttcca atttcaaact
    11821 gactgggaga ttgagctagt tcatgtcaaa gatttggtca agcaggctat tcctttctat
    11881 cagctagatg caccctttgt cgccttttta ccaacctact tagaaggtgg aaatggagtg
    11941 gacaacggag atgtggaaat tctgaccaat cctcttggag attttatcgc tttggggacc
    12001 aatgcagagc tctgtctggg tgtcgttggc tcaggtaacc gcaattttaa caaccaatat
    12061 tgtctgactg ccaagcaata tgctgagcga tttaattttc ctgttataga cacctttgaa
    12121 ctcagaggga tgcagaatga cattgaacgc attggtcgga agataatgga attgatgtaa
    12181 agagcctcaa ctcagcttta tgctgggttg tttttttggt cacacaaaaa aaactcacca
    12241 gagtgactag tgagttttaa ggagattatg aaaaatattt aggattgact atagtatacc
    12301 tcagactata tcgtgtttca tcggtctaaa gtcctatttg tcttctaaaa tgcaaatact
    12361 ctgtcctgca atcgtgattt cttgctgatc acgctcttcg actggaggat agttgtagag
    12421 aactgcctta tctttttcac gttcataggt aaagtcgcta tctgcaaagt tgatgataaa
    12481 ttgaatggtc ttttcttcac ttgtcacttg atagcgaaga acatattcag ttaaccagta
    12541 gaaatcacaa gtttcttgga tactttcgta gttatcctgg ctgagtattg gattattttt
    12601 gcggaaggta attaattcct gaatgaactc gatatgttcc ttataacgaa tagctcgtgt
    12661 ccagtccaga cggttgatac ggtcagggat attgtaagta ttatctattt catcttttgt
    12721 acggaaaaat tcctgtccgc tgtgaatgaa ggccataccc tgagagatta agatgagctg
    12781 gagaccaaaa cttgcagcac gtttctgctg ttgaggtgtc cagtttggat tctcaatatg
    12841 gaaatagtca aatgctgtag cattatcatg gcattcgatg tagttgaggg actgttgagg
    12901 cgttaagaaa tggcttaatc ggctaccagt caggagatgt tgtacctttt cgtgcaattg
    12961 cttatctatt agacggtttg gattgagcaa gagtttctta aaggtatcac ggtaatcgtc
    13021 attgaagaag ctgatttcag gtaaatgctc tgcattgtac tggtgagcca gcttttcaaa
    13081 ttcgaggcct gttgccattt tccatccttc accatagagg tagacatttg ggtgaatggc
    13141 agataattca gtttgaatct ggttgattgt ttcgctatct aaaataccca taaggtcgaa
    13201 acggaagcca tcaaaaccat agagttctag ccattggcga agggattgtt tgatgtagtt
    13261 gcggaccata ctgcgctcgc tggcaacgtc gttaccgcag aatgtcccgt ctgttcgcat
    13321 gccgtggtca tcatagcgat agaagtagcc tggaacgatg agctcaaatg cgtacttttc
    13381 agcatgatag acgtggttgt aaacaacgtc cataataact gaaatatctg catcatggta
    13441 ggcctggata gcttcttgta gctctagaat acgtgcgtaa ggatcgtttg gttggctaga
    13501 ataggaacct tctggcagat tgtattgcat agggtcgtag ccccagttgt aaacagcttg
    13561 gggtttattt tcatccacac tgccaaaatc ataaacaggc aataattgaa tatgggtaac
    13621 gcctagttct ctgatgtaat ccattcctag cttcattcca tccatggtag gagactctgt
    13681 caagccgaga aattgactgc gatgcttgaa accagcttct ttttgccatg agaaatcacg
    13741 gacgctcatt tcatagataa tggcctgaga aataggtcgt tgggtcttag cacgacgaat
    13801 tttatgaagt ttatctggat tgataacgta gctgtcacct gagttggctg tggaagacag
    13861 ggcgtaggga tcgtgaacgg aaatccattc accgtttact ttgtggagat agtgatagct
    13921 gtgcgcttct aggtctcctt caacagtaat ttcccaaact ccttttgctc ccttcgtcat
    13981 tgcatgtggg tttccttcta gaacaagaaa aacttgctta gaaataggtg cccataactt
    14041 aaaggttgtt gcctctggtc gataggttgc tcccaaatct tggccattgt atgtataact
    14101 ttgttcaaaa agtgtagagc gaacgatatg accatagccg agttctgttt tattacggtc
    14161 ttggtcgtag atggtatagt ccttgtccaa tgtcagtgca tggaggctgg ttagataata
    14221 gatgacgaga ttatctactt ctagacagga atggataaaa agttgagatg tagcatcatt
    14281 tgattcaagt gagaagctca tatgttcgga gtcgaatcgt tttttcatga ccaagcgaat
    14341 agttgctaca tcgtcaagag atgcttgaaa ttgtcgtaat gccatgagcc aaaaggctcc
    14401 tttctaagtt agagttcggt aatggtatgt ggaatgacac gtcggtagca gacttgcttg
    14461 tcttccttgt tgtcattgat gatttggtgc agagtgttga atgcgacgcg tcctagttta
    14521 atagcgtgga cgtcaacgta ggcttcaata tctagttttg gcttgacgga gtcaaaagaa
    14581 atgataggaa gtttgactcc gacttcgttg agatatttga caacaccttc ggcaacggaa
    14641 gtgtcagttg tgacgattgc atccaggtct tgtttgagta atttcttaga aattttgtag
    14701 gcactgtctt cgagaaggaa gccagacaca aacttgacct tgttttcatc caggggaata
    14761 ttgtgcgatt taagggcgtt cttgtaacct gtataacggt cttgagatac gactaactct
    14821 ttgttaccag cgacgaaggc aatgtttttg taacctttat tgatgaagta gttggtagct
    14881 tcaaagccgg cctggatatt atcattatca actagtgata tgaatggaga atccgcctta
    14941 ccaagaatga ggaaggggaa tttgtgttgg atagctaatt gtaccaatgg atcgtcgggc
    15001 ttggaataga ggaagatgag gccgtccact cgtttgccgt agaccatctg agaaatcgct
    15061 tctagacgtt gttcttcatt ctttcctgtg gagatttgga tggcataatt atgatctgcc
    15121 gcaacttgag aaattcctcg taaggcagta gggaagaagg ggttttgata gaaaacatcc
    15181 gagtcatctg gcaaaaccag tccgataacc tgtgtatagc tagaaactag gcttcgagcg
    15241 ttgaggtttg gatggtagtt gagatccgcc atggctttcc taaccaagtc tttcgttttt
    15301 tggctaatgg cagagctatt ttgaatgaca cgagtaactg tagatggcga gacaccagct
    15361 aattttgcca catctttgat ggtagcacgc atatagacct cctagatttc atctctgaat
    15421 tttgttttga aaaataccca taacaagcat agtacaaata ggatattttg tatggttaga
    15481 agggtagtca caggttgacc aaatagtcca attagacagg ctataagagt aggcaggccc
    15541 agacagttga gagcaaaatt atagcactct gcaaacgttt caaaatggaa gaaacgagac
    15601 tttttagtca aaaagaggaa gaagctggct cctagtagga tgaagagtag gtttgttgtt
    15661 aaaataaagg tcgaaataag agtgatggac agtccgacag ctgctcggtt ggcttgatac
    15721 cattttttag agatggttgc agtcaaggtc tccttactag caaaatcgtc agtattcaaa
    15781 ccttcataag tcaattcgct tagaatatca cttcctttac gaatagtcag agactgattg
    15841 gcgaattgat aagtaaagtc agaactagag ctaacggtat caccaaatgt cacttgctcc
    15901 cagttagtat ttccagtata ggttaggtgg ttgttttcga tgactgcatg ttgacggagg
    15961 tcatctacga cttgatctgt cagaggtgca tagatacctt ctacgaaatt ttctaaagga
    16021 taggtttcga gattgacagt ctgtagggag ctcggaatga gcaagagcgc cactaaaaaa
    16081 agcgttgtaa acaaccgttg ccaaaggttc attagtctac gattggcaaa catatttctt
    16141 ggagagaaga tactagaaaa ataggaaaaa ggatatggga gcattcgttg gacctttcat
    16201 aaatatcaat gtttccccta aaaagggaaa aggtgggaca gggttatccc ttgtcgccac
    16261 cgcttgttaa accagataca aagttctttt gtaggaagaa gaataggata ctgataggga
    16321 gggcaataag aatggcacct gccgcaaagt aggcaatctt catattcttc acatcactga
    16381 tgaaggtttg aagtccgaca gctacagtat agaattcttt ttcacgaagc aagaatttgg
    16441 ataggatgta atctccaaaa ggtcccatga aggcccagag cgcttgtaca gcaatcattg
    16501 gacgaacgag tgggaggacg atttgccaga aacgtctgaa gtgcccggca ccgtctagtt
    16561 ttgcagattc atcaagtgag attggtaccg tatcgaagta gcctttcatg agccaagcgt
    16621 tcattgggat accaccaccg acataaagga agatgaggaa ccagctttgg ttgagcgcat
    16681 tgagcatgag ggccataacg aagaaggcgg taagagcagc catggttggt accatttgga
    16741 taatcaagaa gaagaccaaa ctctgcttac gagcgatgaa gttatagcga ctataagcgt
    16801 aacccgctag taccactata cttgtttgaa taaccattgt caagagagca atgataagcg
    16861 tattgaagta ccaggttccg tatagagtct cgctaaagag cttgctaaaa ttgtctagtg
    16921 taaagttgat attgctatcc aatttgaagg caaccacgtt accagacttg aaggcggaca
    16981 tgattgtaat caagagagga tagatgatga taacagacag aacaatcaga tagagatagg
    17041 ttaaggtctg attgagtatg cgtctagttt ttacagatac tttcatctta tacatcctcc
    17101 atttcaaaag catttagttt tttgaaggca atcatggaaa tactgatgac aatcattgag
    17161 ataatcaatg taactgctgc cgccattgag tattgaggtg atgtacctgt ggttaattta
    17221 taaatccatg aaatcaagat gtcagttgaa cccgctccac caccgacgct accaggacca
    17281 ccattgttga agaggtagat gatagagaag ttgttgaagt tgaaggtgta ttgactgatt
    17341 agtgttggag ctgctactgc taaaatcatc ggaagggtga tgttacggaa tttttgaatg
    17401 gcacttgcac catcaatgta agcagcttca tacaagtcgt ttggaatgga ttgcaaaata
    17461 cccagggtca aaacatagat ataagggaaa ccaagccaag cctgcatcat aatgagggca
    17521 actttagtcc agaatgggtc ggtcttccaa gggataagga aattatcgat gaatggtagg
    17581 aatttgctca ggaatggcaa tacctgtgtg ttaatagcac caacactatc gttgaacatg
    17641 ttactaaaag tcaagatagt tacgaaggca ggaacagccc atgggagcaa gaagataaca
    17701 ccgaagatgc gttttccttt gatgaatggc tgatttgcga tgatggctgt caagataccg
    17761 ataacaattt gagctgttga agcgcagagt gcccagataa ttgtccagcc aagtacagaa
    17821 ccaaatgctg tacggaatgt gcttagtttc cagatatttg taaagttggt aataccaatc
    17881 caatccaaca atgcgcttgg tggcaggtgt ttgaagtcgt agtttgtaaa ggcgataaac
    17941 aatgtaacga caactgggaa gatgatagca aaggtcatcg caatatatga tgggataatc
    18001 aagagatatg ggaaaccatt ctcatagata ccttttacca tttcttttaa tgtggtagcc
    18061 actggcatcc ttgaattcca tcgtttcgcg gtatcacgtg cgtcttttag gttgagtgca
    18121 tagaaagcga gatagacaac tgtgataatt aagtggaaag aaccacgaat cagcatgaat
    18181 agcgaattat cttgtccacg aacactaccg agggtaatca agttgcctaa ttcaccagct
    18241 gcaatagcaa taaaataaac aaggaaggca agcgtaacac ctaaaaagat gtatcctttg
    18301 gctttttgtt tattgtagat ttgtccgaga ccagggatca gggacaaaag gagtgcctta
    18361 cctggatttt gtttcatagt catagtctcc ttatatagct tctgaataga cggtggatgt
    18421 tatcgtcatt tagtttttct tttattactt cgttaactcg ccttgcctaa cttcagttat
    18481 gcctgcggct cattgcctcg tactaaaagt aaactaaaag actatatcta ttcagtttat
    18541 cgttaagtaa taaagtagac tgggaagaga actcccagtc caactttaaa cttgactagt
    18601 tgctgtgttt ttgagcaatt tcgtctgcaa tagctttcac agcgtctgtt gcagcagtct
    18661 tagcgtcttt tgaaccactt gcagcttcga agagcatgtt accagctggt gtccaaactg
    18721 aacccatttc tgagatgttt ggcattggtt gagctgaagc aaactggttg ataactgcag
    18781 ttgtcaattc gtcttttttg cttacagcat attcacgagc ttcagtgtta gctggaactt
    18841 cgtttgtagc gtcgtaaagt gctttttgtt ggtctgtagc agtcaagaag tcaacaaact
    18901 tttgagccat ttcttggttt ttagcgcctg ctggaacaac ccatgcttta ccaccaccga
    18961 atgctgagta gtttttgccg tttacaagag ttggtattgt tgctacacca tagtttacac
    19021 cagcttcttt atatgaagct gctttccaag gaccttcgat gatagcagct gctttaccgt
    19081 ctgtaaattg agtgttaatc aagttgtttg cagcagtacc gtcttgaaga ccttgaggcc
    19141 atttttcgta ccaagtttta gcgtattcaa ttgctttgat agcaccttca ttagcaagtc
    19201 cgatgtcttt tggatttgta ccattttcac cgaatacata gccgccgtaa ccagaaagaa
    19261 gtccgtatgt atagtagaaa ttcgtccagt cagctaggaa tgctgaagtt ttaccctctt
    19321 caccagcaaa tgcgtatttg ctgtctttag caagtgtttc aagttctgca aatgtcttag
    19381 gagcttcagt caacaagtct ttgttgtagt aaagaacaag tgtttcgata accgcaggtg
    19441 aaccgtaaac tttaccaccg tttgttacaa gagcagttgt tgtgtcatct gctttgctat
    19501 catctgcaag agtcaattca gatagttgac cttcagaacc aaggctacct acacggtcgt
    19561 atggtgccat cataacgtct ggggctgaac cagattggtt atccaacgat aagttatcca
    19621 aaccagttaa agcatcacca gttttaacgg taacagatac accattttct ttttcgaagc
    19681 cagctttgac atcgttgatg taagattcat aaccttggtc aacgtagaca gtcaattctt
    19741 tgctaccttc agcagactta gatgcctctg ttgatgaacc tgagtttgag catgcagcta
    19801 aaacagcagt tgatgcagca agaagagcaa cgctcttaag gagattgtgt ttcattttct
    19861 tccctccgaa gataaatagt tttgtgtgac gcttgctttg cgcaaacgtt ttcctaagtt
    19921 gacttcatta tacactagat tgaatccgtt tgcaagcgtt tttataaaaa tttttaaaaa
    19981 tttttttgag tttaaaaaaa tataagaatt tttttgcata tattaatgaa aagaaatatg
    20041 gaatggcatg tgaactaaca gaattaaatg gaaatttctt gatttgttac cgttttcagt
    20101 atataataaa aaagagaaaa cgtttgcgtt gtgcaagcgg attagatagg agaacttatg
    20161 aaagtaagac agagtggtgt gctgatgcac atttcatcat tacctgggaa atatggaatt
    20221 ggttccatgg gccaatcggc ttatgaattt gttgattttt tggtaagaac taagcaacgc
    20281 tattggcaaa tcttaccttt gggaacaacc agttatggag attctcctta ccagtcattt
    20341 tcagcttttg cagggaatac tcattttatt gattttgata tattgattga taaaggctgg
    20401 ctggcagcag aggatttaca cggtgttgac tttgggcaga atcctacaga ggtagattac
    20461 gcagccattt tttatgctcg acgtccatta ctggagaagg tagttgccaa catgaaggca
    20521 caaggcttgc cagaagatta ttggatgttc ttaggggaga atgacttttg gattcatacc
    20581 tttgcggagt atatggctat aaaagagcat tttgatctca aaccttggac agagtgggaa
    20641 gatcaagggg cgcgcttacg ttaccacgat accttggaat attatcgtca cttgttggca
    20701 gatcgaattg attatcaccg cattacacaa tatttattct tttcacaatg gaaggcttta
    20761 aaggcttatg ccaatgccaa aggtgttgag tttgttgggg atatgccgat ttatatcgcg
    20821 gctgattctg ccgatatgtg ggctaatcca catttcttta aaacggatga agaaggcaag
    20881 ccgagtgtgg ttgcaggatg cccaccagat gccttttcgg aaattggtca gctttggggc
    20941 aatccgattt atgattggga agcgatgaag catgacggat ttacttggtg ggttgctcgt
    21001 ttacgtgaat cctttaagat atacgatatg gtacgtatcg accactttat cggctttgcc
    21061 tccttctggg aaattccagc gggtgaagaa acagctgtaa atggctatcg tgtcgaagca
    21121 ccaggttttg agttatttga tacaatcaaa cgtgaactcg gagacttaaa tatcatagct
    21181 gaggatttgg gctctgtgac agacaaggtc atccaattac gtgatacgac aggttttcct
    21241 ggtatgaaag tcctgcagtt tgcttttgat ccagaaggag acagcattga aatgccacat
    21301 aaccatccta ataatgtggt ggcatatacg ggaacccatg acaatgatac gattcttggc
    21361 tggtacgaaa atgaaacaac gaaagaatcg cgtgcattct tagataagta cagcaatcgt
    21421 cgtgaggggg aaacggtcag tcatgctctt ttccgtctgc tctttggttc acctgccttt
    21481 atggcggtgg ctactatgca ggacctactt ggtttggatg gttcagctcg catgaacttg
    21541 ccaaatacgc ttggtggtaa ctggacttgg agaatgacgg cagatcaatt gacaccagag
    21601 attgaagcgg aattgctaga ccttacagaa acttatcgtc gggttaatgt gcatttggtt
    21661 gatgaaaagt cataataaaa tgaactcctc taagcagcta acttagagga gtctttgtta
    21721 tctctgttgt aggacataga gccagtagcg aatccagtag tagatggtgt agagtaggca
    21781 ggctacgata gtccaaatga aaaatgtatt cagcacttta gcaagacttg gcaataacca
    21841 gttaatcagt agagtgacta caaaaataat cactccgata taggtgggca atttcttcat
    21901 gagttttcct cctttgaact tagtataaca aaattatatt tgcagtcaaa tgaaat
//
LOCUS       DBNFCO010000032        21125 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.032, whole genome shotgun sequence.
ACCESSION   DBNFCO010000032 DBNFCO010000000
VERSION     DBNFCO010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 21125)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21125)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21125
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.032"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            <1..276
                     /locus_tag="AC1PIV_001005"
     CDS             <1..276
                     /locus_tag="AC1PIV_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012774973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612037.1"
                     /translation="ENEKREQFSKYLNLFALSDNITALKELNVFDEWDSVLKTLNKPG
                     TRWGQVQKTTINLAFARYLDSNNFVSSINERSNDIRLNSYKDKTIPL"
     gene            335..1426
                     /locus_tag="AC1PIV_001006"
     CDS             335..1426
                     /locus_tag="AC1PIV_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HIP6612038.1"
                     /translation="MSISGIIAEYNPFHTGHKYLLEQAEGLKIVVMSGNFMQRGEPAI
                     VDKWTRAQMALEHGADLVVEMPFLVSVQSADHFAKGAISILHRLGVEKLVFGTEEMLD
                     YQKIADIYVDKSEEMENFVKNLPDNFSYPQKTQAMWQEFAGLTFTGDTPNHILALAYA
                     KGVAGTGIQLSPVQRQGAGFHSEEVETSYASAIAIRKGADQLDLVRDFLPSASLFEEA
                     TKVSWRNYFPLLRYQITTHPDLSQVFQVNEELASRIRSAIGSVATVEELVEAVTTKRY
                     TKARVRRVLTYILINAVETPLPDAVHVLGFSARGQAYLKQVKERVGLVTRIGKEPWDS
                     LTQQADLVYQLGADAMAEQTYGRVPVRVE"
     gene            1522..2241
                     /locus_tag="AC1PIV_001007"
     CDS             1522..2241
                     /locus_tag="AC1PIV_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HIP6612039.1"
                     /translation="MKTVKEMSQLSGISVRTLHYYDEINLLTPSFIAENGYRYYDNEA
                     FEKLQEILLFRELEFPLKEIKKIVGNAAYDRESALKDQIRLLELKKKHLEKVIKHAKS
                     LQQKGENYMNFEVFDKSDLLAFQEEAKERWGNTAAFQEFSAKTNQEGFAHISAEMSGI
                     MMEFGKMKSLSADDSKVHKQVEVLKAYISENFYNCTNEILASLGQMYIADNRFTQFID
                     QVGGEGTASFVSQAIAVYCKE"
     gene            2337..4871
                     /locus_tag="AC1PIV_001008"
     CDS             2337..4871
                     /locus_tag="AC1PIV_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dynamin family protein"
                     /protein_id="HIP6612040.1"
                     /translation="MTKIKIISNPFHKSIVFQKQQPITEVWEEITFESNPNSRLVREN
                     IQKGVLSFHIQEIVDILVAEYDDGTGIDLLFEGNSDEFQELKTFVQSLNNSSISLKKS
                     AYSLTNARDILPEVLSIFDKTQVILPEELEHDAAIQKFQDATKPQIPLLVLGNYSAGK
                     STFINSLVGYELLPASDQPTTAKIIQIEKFAEKWIEIEGTLLRNKVCIRIDEDGFEVE
                     GDRIDETIIKDLESIRQSLPQTTPQILARAVLAYLNAREDSDLNIITVKTAFTDSPLS
                     KSSHRYIIFDTPGSNSSTNMEHLQLLREAMAGMSNGLPIFISEYTSLDTVDNDKLYQE
                     LEQIDGIDLRYTILVVNKADTAALSTFQDHQVLNQALPRKLSTKRVYFLSSLMGLGSK
                     TSGLFQEPDYERVYQKSLAEFTDASNPYYQQLYTYNILPTQQKLAQELQSKEERNLLY
                     ANSGLYSLESEIEVFSTKYAAYNKCVQADQYLQHIISQTQSIIEDSKKTIEQEKDRLE
                     KKLEKDKLALVNDLKRQQADFFNSSSTVYQQNLNEKVRDEKHYAPLQLFIKERDSLWS
                     KAVDDFQLKSYQKEMAESPKKALNNIKNSLGKAWDKKNIEILGSAFVNGFNDTGKVFS
                     KVDDYNKMKTKAKGQVRDQLITFARFEYIKQVEEVGKDFTTLSIHYWKEQTGLIKDRF
                     SQLIGDASVLSDQKRAAIKEIIFQFQQPVLYHDSKQLFDQKSLVEGFRLGDIQIFGDA
                     NKIDLQKLEKRYNSLLKTAYKHINEQLISHHQATFYKWVEALLHLVTENIVEFSPDLH
                     STNLLIQDNRVKIEELSTNLQNLHEYSKDLHDLMAWKDDEEVANGY"
     gene            4861..8199
                     /locus_tag="AC1PIV_001009"
     CDS             4861..8199
                     /locus_tag="AC1PIV_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HIP6612041.1"
                     /translation="MVIKKMIKKVATKAADGVSKLSELSPEQLEKVQAQMATYRDQIP
                     DLSGEAAEEYFRKQLAIAGVEVYNAYLPQLKDLYLPIDNKTEFRLEDEGVLIDEGEFK
                     SGYNIRYINITKWVTDKQENSLEKLVSVYEVLSTTPCNISLVFHRKQEETSVYLAVTN
                     TENADSNADVDSYRKRLVSAIKGNFPGAAWKEEVGRGSLPCFEDYIPYSVATASNIPT
                     EKSEKFISQTIEKLLDGIVPENKEQEYILVLLATPVLDVTDRKLHLSQIYSNLSPYAT
                     WQTQFQLTESDSRGSSATVGVNIGASVGSQTGHNLTQTHSQGQTESRGTSETETNTKG
                     SGWQAGVNIKILNGGHNWNKSKSIAKGITNTIGKTASVANAVGKTVSSSLGANFGANF
                     ARTSSVTATIGKNEGISQSFVNHHVQHALKNLDKQMERLELSTALGLWDFSAYVLSED
                     PTIANNVAHSYLALTQGEESHLSQTVVNLWRGDVQMERDKAKALIAYLRDLRHPLFGF
                     NPEILEIDEEFAVYPEIVTAATPLSGKELAYALNFPQKSIAGLPVLECAQFGRNISTF
                     EEKDDQEQLPLGNIFHMNHEENTAVQLSLPSLASHTFITGSTGTGKSNTVYQLLAQAR
                     EKGIKFLVVEPAKGEYKQVFGSDEDVAVFGTNPTITPLLKINPFSFPEGIHILEHLDR
                     LVELFNVCWPMYAAMPAVLKKAIEQAYQDCGWDLISSVNTYSKTIFPTFADVLRTIRE
                     IIDSSEYDNDNKGAYKGALLTRLESLTTGIYQLMFTEDEISSEKLFDENVIVDLSRLG
                     SSETKSLIMGLLILKMQEYRMVSSQGMNQQLRHVTVLEEAHNLLKRTSTEQATESSNL
                     LGKSVEMLTNAIAEMRTYGEGFIIADQSPGLLDLAVIRNTNTKIILRLPEYSDRELVG
                     KSANLNEEQINELAKLPKGVAAVYQNEWLEPVLCKVAKYDSTEMVFQQPTQLVRTESP
                     YHRLAILELLTTSPNLDSTLSFEELQELTLAVGLDSLTQVRIFNFLRTTSPDNFSMHE
                     LAHILGKVYPELVEKIRLKAEKGLEPPALTQVLQQEIDSSIPETISEQARRDLVQGLM
                     TCYYLFELKDHKAMQDWLRNGDLI"
     gene            8196..8795
                     /locus_tag="AC1PIV_001010"
     CDS             8196..8795
                     /locus_tag="AC1PIV_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH/ENDO VII family nuclease"
                     /protein_id="HIP6612042.1"
                     /translation="MIEGLKTVAEAVKPVVNEVGKRAIDAFEKPIDSDKRLEAASDNK
                     TTFRYDGLSKPQEFLAQAQGFPKEIAKDIYNSQELKHYMDIGMRAVQFGQKENGEPRF
                     CLIPKDLSFDRVVDSQGRTNAERLQSGLLPIKDGQPLEVHHIGQKNGGHYALLTKEEH
                     IKNGNKEMLHKPGKSDVDHGLDFARDKRSIAKVLMEEQV"
     gene            8792..9202
                     /locus_tag="AC1PIV_001011"
     CDS             8792..9202
                     /locus_tag="AC1PIV_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMI1/KNR4 family protein"
                     /protein_id="HIP6612043.1"
                     /translation="MSQLVDKIKVVQGLYSGSPASEQEVAVAESKLQLIFPAEYKDYL
                     KEYGVISFYGTEWNGLKGDTWTDVVATTLEARSLYENFPKEKFILEDLHFDDMLVLAD
                     STGKVFLWHNGLEKEIHSSIASYLEECVARKDTP"
     gene            9199..9609
                     /locus_tag="AC1PIV_001012"
     CDS             9199..9609
                     /locus_tag="AC1PIV_001012"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HIP6612044.1"
                     /translation="MIQPIMKDIFFLQQKSEPATQLDVQVGQDLQDTLAANAHACVGM
                     AANMIGVKKRIIIVNMGFTNLVMYNPVLISKAKPYQTEEGCLSLEGTRPTTRYQEIEV
                     EFFDASWKKISLKLTDFQAQIVQHELDHLEGIII"
     gene            9914..12013
                     /locus_tag="AC1PIV_001013"
     CDS             9914..12013
                     /locus_tag="AC1PIV_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012774978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HIP6612045.1"
                     /translation="MNNNFNNFNNMDDIFNQLMGNMGGYSTERRRYSINGREVTPEEF
                     AMYRQTGRLPQTEEVAQTQAKGQIKSDGILAKLGRNLTQDAREGKLDPVIGRNKEIQE
                     TSEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGLEA
                     GTQYRGAFEENVQNLVDEVKKAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKPAL
                     SRGELTVIGATTQDEYRNTIHKNAALARRFNEVKVNAPSAEDTYQILKGIKPLYEAHH
                     NIELPDEVLRAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDIQTLEAEMAE
                     AKQLQLEAAEKEDYEKALNEKVRIDKLQKQIDNHTEQQKVVATVNDVAQAVERMTGIP
                     VSQMGASDIERLKELKNRLAANVIGQDDAVEAVSRAIRRNRAGFDDGNRPIGSFLFVG
                     PTGVGKTELAKQLALDLFGNKDAIIRLDMSEYSDRTAVSKLIGTTAGYIGYDDNSHTL
                     TERVRRNPYSIVLMDEIEKADPQVITLLLQVLDDGHLTDGQGNQVNFKNTIIIATSNA
                     GFGYGMAEGEENQDIMDRIAPFFRPEFLNRFNAVIEFKHLDKDDLKAIVELLLAQVNN
                     TLAKKGIQLTVTEAAKEFLMEEGYDKAMGARPLRRVIENQIRDKVTDFYLDHVDVKYL
                     EADVVDGSIQIKEQSFA"
     gene            12196..13704
                     /gene="malQ"
                     /locus_tag="AC1PIV_001014"
     CDS             12196..13704
                     /gene="malQ"
                     /locus_tag="AC1PIV_001014"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004134 - 4-alpha-glucanotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005980 - glycogen catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HIP6612046.1"
                     /translation="MTNRTSGILMHITSLPGKFGIGTFGQSAYDFVDFLVETKQTYWQ
                     ILPLTTTSYGDSPYQSFSAIAGNTHLIDFDLLVEDGLLATEDFQDVNFGDNPEKVDYA
                     LIYQVRRPILEKAVQAFLQDDKKKAAFLEFEKANSSWLTDYAEFMAIKEYFGNKALQE
                     WEDKKVVARNEEALDKYRLELANQIDYYKVTQYFFFSQWKQLKEYANKHHIKIIGDMP
                     IYVSADSVEVWTKPQLFKLDSERKPLYVAGVPADNFSADGQLWGNPIYDWPEHEKTGY
                     NWWIYRIHESFKLYDVLRIDHFKGFSDFWQVDGKAEVAKVGTWEPGPGYNLFKAVKET
                     LGDLPIIAEDLGNIDAKARKLLADCGYPGMKILEFGFFDVTGKSIDAPHRCIPNSVAY
                     TGTHDNEVVNGWYNNLDPEQQEYVDAYSNRKPIEKVSQAMLRMLFATVSDTAIATMQD
                     VLDLGEESRMNMPSTIGGNWEWRMKAEDLTQERKDFLTKMTLLYQRGNENHD"
     gene            13697..15961
                     /gene="glgP"
                     /locus_tag="AC1PIV_001015"
     CDS             13697..15961
                     /gene="glgP"
                     /locus_tag="AC1PIV_001015"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004645 - 1,4-alpha-oligoglucan
                     phosphorylase activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HIP6612047.1"
                     /translation="MTKFTTFAETNTSKKLADLTNEEIYLQLLNYVKDAAASKPKNTG
                     KRKVYYISAEFLIGKLLSNNLINLGVYKDVQAELAAAGKSLAQVEDVEPEPSLGNGGL
                     GRLASCFVDSMSTLAINGEGVGLNYHCGLFRQVFKKNEQEAEPNFWIENDSWLIPTTI
                     SYDVPFKNFTLKSKLDRLDILGYKKETKNYLNLFDIESVNYDLITDGISFDKTDIKEN
                     LTLFLYPDDSDKNGELLRIYQQYFMVSNAAQLLIDEAIERGSNLHDLADYAYVQINDT
                     HPSMVIPELIRLLTEKHGIEFAEAVAIVKNMTGYTNHTILAEALEKWPLEFLEEVVPH
                     LVDIIKELDALIRAEIKDPAVQIIDESGRVHMAHMDIHFSNSVNGVAALHTEILKNSE
                     LKAFYELYPEKFNNKTNGITFRRWLEFANQDLADYIKELIGDEYLTDATKLEKLLAFA
                     DDKEVHAKLAEIKFNNKLALKRYLKDNKGIELDENSIIDTQIKRFHEYKRQQMNALYV
                     IHKYLEIKNGNLPKRKITVIFGGKAAPAYIIAQDIIHLILCLSELINNDPEVNKYLNV
                     HLVENYNVTVAEKLIPATDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIA
                     ELAGMDNIYTFGKDSDTIIDLYDKAGYVSADYYNGDANIKRAVDFIVSDEVKALGNEE
                     RLGRLHHELISKDWFMTLIDLAEYIEVKEQVFADYEDQDSWNKKVVHNIAKAGFFSSD
                     RTIEQYNEDIWHSN"
     gene            complement(16189..16896)
                     /locus_tag="AC1PIV_001016"
     CDS             complement(16189..16896)
                     /locus_tag="AC1PIV_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018367901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTRA domain-containing protein"
                     /protein_id="HIP6612048.1"
                     /translation="MSKYKKVYQDIKKKIEEQVWSTGQALPTENELMEVYSYSKDTIR
                     KALSLLEMDGYIQKKQGKSSIVIEHGLMKDQYLSEIKTAGELNKRSQHQIQTQLTSLY
                     IIQGQEDLMSTFEVDDKVDFYRVSRVRTIDGERLEYDISYFDRRVVPYLSKEIAESSI
                     YRYLEEELHLTISHSRREISFRFANEEEKQLMDLGDYDMVVVVTSITYLSNGQAFQYG
                     TISYRPDKVSFVSMAKR"
     gene            17095..17886
                     /locus_tag="AC1PIV_001017"
     CDS             17095..17886
                     /locus_tag="AC1PIV_001017"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HIP6612049.1"
                     /translation="MKLLTINVHAWLEERQDEKLDVLAQTIAEKAYDVIALQEVNQLI
                     TADLVTKDLKADNYGLILLEKLRTLGQFDYSYYWSNSHIGYDKYEEGIAFLTKLPVYE
                     VDQFYCSQNKSIDSILSRKIMGLTVFYQDQLIDLYSCHINLPGSEEEDQLDNIRTIVE
                     RTGNRRFKILMGDFNTDAFSDREAYEAITELGLYDSYNLAMEKDQGITVEKAIDGWAG
                     HSQEKRLDYIFLNQKKEVLSSLVIFNGENRPIISDHFGVEVEINV"
     gene            17920..20088
                     /locus_tag="AC1PIV_001018"
     CDS             17920..20088
                     /locus_tag="AC1PIV_001018"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIBC"
                     /protein_id="HIP6612050.1"
                     /translation="MKKFLSFEFWQKFGKCLMVVIAVMPAAGLMVSIGNSIPLISPES
                     ELLIRIGNIIAQIGWGIIGNLHLLFALAIGGSWAKEKAGGAFSAGLAFILINLITGHF
                     FGVTTDMLADAAATVTTVFGTEIPVSGYFVNILGQPALNMGVFVGIIAGFVGATTYNK
                     YYNYRKLPDVLTFFNGKRFVPFVVIYRSVLVALGLAIFWPVVQTGINSFGKWIASSQD
                     TAPILAPFVYGTLERLLLPFGLHHMLTIPMNYTSLGGTYDILTGAQAGTQVFGQDPLW
                     LAWITDLINLKDAGDMAQYNDLLANITPARFKVGQMIGSSGILMGLTYAMYRNVDEDK
                     KHKYKGMFISSALAVFLTGVTEPIEFMFMFAAMPLYVVYAFVQGAAFAMADIVNLRMH
                     SFGNIEFLTRTPMAIKAGIGMDVINFIWVTALFAVGMYFIANFMIKKFNLATAGRNGN
                     YDTETTDVVSNSNVDTADANSQVVQIINLLGGRDNIADVDACMTRLRVSVKDVAQVGD
                     ENAWKQAGAMGLIIKDSGVQAVYGPKADVLKSDIQDLLESGVAIPRTEIVATEEVAPE
                     TQFKGVTETVYSVAEGQAIAITEVKDPVFSQKMMGDGYAVEPSSGNVYAPVSGIVTSV
                     FPTKHAVGILSDKGVEVLVHIGLDTVALNGAPFSTKVTDGQRVEAGDLLLVADLEAIR
                     SAGRETTIVVAFTNTAEIKSVSLENLGQVSQDSQVATVEL"
     gene            complement(20159..20785)
                     /locus_tag="AC1PIV_001019"
     CDS             complement(20159..20785)
                     /locus_tag="AC1PIV_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HIP6612051.1"
                     /translation="MIRHKLFTSLQEEEHWINSIQSEGYQLVKVTPWTATYHFEKCSR
                     TPHPVRLDFHEHIAKGEYSNYLSLFEDCGWQPIQGSRRCGIHYFQQTIETSSTEIFSD
                     TESKKAFYSRYQNYAYSYFGLFLTLFFIHYQVGLQNGYTLWNPKSWYLTPGLWERTGT
                     SFWFGFLFETPFALFRSGIIPLFFLAWSIYFLHIAEKGKKEAKKLEKY"
     gene            complement(20796..21107)
                     /locus_tag="AC1PIV_001020"
     CDS             complement(20796..21107)
                     /locus_tag="AC1PIV_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HIP6612052.1"
                     /translation="MKRNKHLPLTETTYYILLALLEPAHGYHIMQKVEDMSDGDVKIA
                     AGTMYGAIENLLKLKWICSVPSSDKRRKVYQVTATGQEIIKLETQRIQKLHHIAKELG
                     F"
BASE COUNT         6621 a         3886 c         4629 g         5989 t
ORIGIN      
        1 gagaatgaga agcgagagca gttttctaag tatttgaatc tatttgctct atcggataat
       61 attacagctt taaaggaact caatgtattt gatgagtggg atagtgtatt gaaaacatta
      121 aataaaccag ggactagatg gggacaagtg caaaaaacaa caataaactt ggcatttgca
      181 agatacttag atagtaataa ttttgtaagc tcaattaacg aacgaagtaa cgatatccgc
      241 ttaaatagct acaaggataa aactatacct ttgtagacct atgttagact atgatagagt
      301 tgtcgaatta aaatacaaaa aataggagaa atgcatgtct atttcaggga taatagcaga
      361 atacaatccc tttcacacgg ggcataaata cctgctggaa caggccgagg ggctgaaaat
      421 tgtcgtcatg tctggcaatt ttatgcaacg gggtgagcca gccattgtgg ataagtggac
      481 acgggctcag atggctttgg aacacggggc agatcttgtt gtcgagatgc cctttttggt
      541 gtcggtccag tcggctgacc atttcgccaa gggagcaatc agcattttac acaggctagg
      601 tgtggaaaaa ctggttttcg gtacagaaga aatgctggat tatcagaaaa ttgcggatat
      661 ctatgtggat aagtcggaag agatggaaaa ttttgtgaaa aacttgccag acaatttctc
      721 ttatccacag aagacccagg ccatgtggca ggaatttgcg ggtctaacct tcacaggtga
      781 tacgccaaat catattctgg ctctggctta tgctaagggg gtggctggaa caggcattca
      841 gctcagccct gttcaacggc agggagctgg ttttcattcg gaagaggtgg aaacgtccta
      901 cgcctcggcg atagctatcc gaaagggtgc tgaccagctg gacttggttc gtgacttttt
      961 accgtctgcc agtctctttg aagaggcgac caaggtaagc tggagaaact attttcctct
     1021 gctccgctac cagattacga cccacccaga tctcagtcag gtctttcagg tgaacgaaga
     1081 actagccagt cgtatccgct ctgccattgg gagcgtagcg accgtggagg agttagtgga
     1141 ggccgttacg accaagcgct acaccaaggc gcgggtgcgg cgggtgttga cctacatcct
     1201 gattaatgcg gtggaaactc ccttaccaga tgcggtccat gtgctaggct tctcggctcg
     1261 aggtcaggcc tatctcaagc aggtcaagga gcgagtgggc ttggtgacgc ggatcggtaa
     1321 agagccctgg gacagcctga cccagcaggc ggatttggtc tatcaactgg gcgctgacgc
     1381 aatggcagag cagacctatg ggcgcgtgcc ggtgagggtg gagtgagaat ctgagttgaa
     1441 aatagaaaat ttttataatt tttcccttga ctctaacgct gggtcataga ttatactgct
     1501 atttatgaga ggagattatc catgaaaaca gtgaaggaaa tgagtcagct ttcaggtatc
     1561 agtgtgcgca cacttcatta ttacgatgaa ataaatttgc tgacacctag ttttattgcg
     1621 gaaaacggat atcgttacta tgataatgag gcgtttgaaa agttgcaaga aatcttactt
     1681 tttcgtgaat tggaatttcc tctcaaagaa attaaaaaaa ttgtagggaa tgcagcttat
     1741 gatagagagt cagctttgaa agaccagatt agattactgg agttgaaaaa gaagcacttg
     1801 gaaaaagtca taaagcatgc caagtcttta cagcagaagg gagaaaatta catgaatttt
     1861 gaagtgtttg ataagtctga tttgttggct ttccaggagg aagctaaaga aagatggggt
     1921 aataccgcag cttttcagga gttttctgct aagacgaatc aggaagggtt tgctcatata
     1981 agtgcagaaa tgtctggtat tatgatggaa tttggaaaaa tgaagagttt atcagctgat
     2041 gattctaaag ttcataaaca ggtagaggtt cttaaagctt atattagtga gaatttttat
     2101 aattgtacca atgaaattct agcaagtcta ggacaaatgt atattgcaga taaccggttt
     2161 actcaattta ttgatcaagt gggaggagaa ggtacagcgt cctttgtcag tcaggcaata
     2221 gcagtttatt gcaaagaata aacgaaagaa gtctagtgag aactaggctt ttttagtatt
     2281 atgaaaacgc tttatatatg gtataataaa acatagaata aagatgggga tctagtatga
     2341 caaagataaa aataatcagc aatccatttc ataaaagtat tgtttttcaa aagcaacaac
     2401 cgattacaga agtttgggag gaaattacat ttgaatccaa tccaaatagt cgtttggtaa
     2461 gggaaaatat tcaaaaaggg gtgctatcat ttcatatcca agaaatagta gatattctgg
     2521 tggcagaata tgatgatgga acagggattg acttgttatt tgaaggaaat agtgatgaat
     2581 ttcaggagtt gaaaacattt gtccaatcgt taaataattc ttctatttct ttgaagaaat
     2641 ctgcttatag cttgacaaat gcacgagata ttctacctga agttctttct atttttgata
     2701 aaactcaggt cattcttcct gaagaacttg aacatgacgc agccatacaa aagtttcaag
     2761 atgcaacaaa acctcagatt ccattattgg ttttgggaaa ttatagtgca gggaagtcta
     2821 cttttatcaa ttcattggta ggatatgagt tattgcctgc cagtgaccaa cctacaacag
     2881 cgaaaattat acaaattgag aaatttgctg aaaaatggat tgaaatagaa ggaacacttc
     2941 taagaaataa ggtttgtatc cgaattgatg aggacggctt tgaggttgaa ggcgacagga
     3001 ttgatgagac aattatcaaa gatttagaat ccattcgtca gagtttgcca caaacaactc
     3061 cgcaaatact agcacgggct gtgttggctt atttgaatgc tagggaagat agtgatttga
     3121 atattatcac tgtgaaaaca gcgtttaccg atagtccact gtcaaaatct tctcatcgct
     3181 acatcatatt tgatactcca ggttccaatt cttcgaccaa tatggagcat ttgcagcttc
     3241 ttcgtgaggc tatggcgggt atgagcaatg gtttgcctat ttttatatcg gaatacacta
     3301 gcttagatac tgtagacaat gataaactct atcaggaatt agaacaaata gacggaattg
     3361 atttacggta tacaatacta gttgttaaca aagcagacac tgcggcctta tcaacttttc
     3421 aagatcatca ggtattaaat caagcccttc caagaaaatt atcaacaaaa agagtttatt
     3481 tcctatcctc tctaatgggc ttggggtcaa aaaccagcgg tcttttccaa gagccagatt
     3541 atgagagagt ttatcaaaaa agtttggctg agtttacaga cgcttcaaat ccttattatc
     3601 aacagttgta tacttataat attcttccaa ctcagcagaa actggctcag gaattgcagt
     3661 ctaaggagga gagaaatctt ctctatgcca acagtggact gtacagttta gagtcggaaa
     3721 ttgaggtttt ttcaaccaag tatgcggctt ataataaatg tgtacaggcg gaccagtatt
     3781 tgcagcatat tatttctcaa acgcagtcaa tcattgaaga ttccaagaaa acaattgagc
     3841 aagaaaaaga tcgtttagag aaaaagttgg agaaagacaa gctggcattg gtgaatgatt
     3901 taaaacgcca acaagctgat tttttcaatt cctcatcgac ggtataccaa caaaacttga
     3961 atgagaaagt aagggatgag aaacattatg ctccgttaca actgttcata aaagagcggg
     4021 actctctatg gagtaaggca gttgatgatt ttcaattgaa atcctatcaa aaagaaatgg
     4081 cagaatctcc taagaaagcc ctaaacaata tcaagaatag tttaggaaaa gcctgggata
     4141 agaaaaatat tgaaatccta ggttcagcat ttgtaaatgg ttttaacgat acgggaaaag
     4201 tgttttcgaa ggttgatgac tataataaaa tgaagaccaa ggccaaaggt caagttcggg
     4261 atcagttaat tacttttgca aggtttgaat acattaaaca agtggaagag gttggaaaag
     4321 actttacgac tctgtcaatt cattattgga aggagcagac aggattgatt aaagatagat
     4381 tttctcagct cattggtgat gcgtccgtat tgtcagatca aaagcgggcg gctattaaag
     4441 aaatcatttt ccaattccag cagccagttt tgtaccatga ttccaagcaa ttatttgatc
     4501 aaaaatcatt ggtagaagga ttccgtttgg gagacatcca gatatttggt gatgccaaca
     4561 agatcgattt acaaaagcta gaaaaacgct ataatagttt gttaaaaact gcttacaagc
     4621 atatcaatga gcaattgatt agtcaccatc aagcgacttt ttataaatgg gttgaagcct
     4681 tattgcattt ggtaacggag aatattgtag agtttagtcc agaccttcat tctacgaatt
     4741 tgttaataca ggacaaccga gtgaagattg aggaattatc aaccaacttg caaaatctac
     4801 atgagtattc taaggacttg cacgacttga tggcatggaa agatgatgag gaagtagcaa
     4861 atggttatta agaagatgat aaaaaaagta gctaccaagg cagcagacgg tgtttcaaaa
     4921 ttatcagaat tgagtccaga gcagcttgaa aaagtgcagg ctcaaatggc gacttatcgg
     4981 gatcaaattc ctgatttgtc aggtgaggct gcggaggaat actttaggaa acagttagca
     5041 attgctggcg tagaagtcta taatgcctat ctacctcagt taaaagacct ttatcttccg
     5101 attgacaata aaacggaatt tcgtttagaa gatgagggag ttttgatcga tgaaggcgaa
     5161 tttaagagtg gttataatat ccgctacatc aacattacca agtgggtgac ggataagcag
     5221 gaaaatagtt tggagaaact ggtcagtgtt tatgaggtct tgtcaacaac tccttgtaat
     5281 atttctcttg ttttccaccg taaacaggag gaaacatctg tatatttagc ggtcactaac
     5341 actgaaaatg cggatagtaa tgcagatgtt gatagttacc gcaagcgatt ggtctcagct
     5401 atcaagggaa attttccagg tgcagcttgg aaagaggagg ttggaagagg tagcctgcct
     5461 tgttttgagg actatattcc ctactcagta gcaacagctt ctaatattcc aacggagaaa
     5521 tcagagaagt tcatcagtca gacaatcgaa aaattattgg atggcattgt acctgaaaac
     5581 aaagaacaag aatacattct tgtcctcctg gcaacgccag ttttggatgt tacagataga
     5641 aaattgcatc tttctcagat ttattctaac ctatctcctt atgccacttg gcagacccag
     5701 ttccaattga cagaatcaga ttccagaggc tcttctgcaa ctgttggggt taatattggt
     5761 gccagtgtcg gaagccagac aggtcacaat ctaacccaaa cccattcgca aggtcaaact
     5821 gagtcaagag gaactagtga gacggagacc aataccaaag gaagtggttg gcaagcaggt
     5881 gtaaatatta aaatactcaa cggaggtcat aattggaaca aaagcaaatc aatcgccaaa
     5941 ggcatcacca atacaatagg caaaacagcc tcggttgcca atgccgttgg gaaaacagtt
     6001 tctagcagtc taggtgccaa ttttggagct aattttgctc gaacttccag tgtgactgct
     6061 accattggga aaaatgaagg cattagtcag tcctttgtca accaccatgt tcagcacgct
     6121 ctaaaaaatt tagacaagca gatggagcgt ttggaattgt ctactgcctt gggactatgg
     6181 gatttttctg cctatgtttt gagtgaagat ccaactattg ccaataacgt tgcccattcc
     6241 tatttggcct tgactcaggg agaagaatcg catctgtcgc aaacagttgt caatctttgg
     6301 cgtggggatg ttcaaatgga acgtgataag gctaaagcac tgattgccta cttgagagat
     6361 ttacgccacc ctctctttgg tttcaaccca gaaattctag agattgatga agaatttgca
     6421 gtttatccag aaatcgtcac agcagccacg ccactgtctg gaaaggaatt agcctatgct
     6481 ctcaattttc ctcagaaatc gattgccggt cttcctgttt tagagtgtgc tcagtttggt
     6541 cgtaatatct ctacttttga ggagaaagat gatcaggagc aacttccttt gggaaatatt
     6601 ttccacatga atcatgagga aaatacagca gttcagcttt ccttaccttc cttggcctcc
     6661 catacattta ttacaggtag tacaggtaca ggtaagagta ataccgtcta tcaattgctc
     6721 gctcaggcta gggaaaaagg aattaaattt ttggttgtag agccagctaa aggagaatat
     6781 aagcaggttt ttggctcaga tgaggatgtg gcagtttttg gaaccaatcc aactatcact
     6841 cccttattaa aaataaatcc attcagcttc cctgaaggca ttcatatcct agaacattta
     6901 gaccgtcttg tagaactctt caatgtttgt tggccaatgt atgcagcgat gcctgctgtt
     6961 ttgaaaaaag ccattgaaca agcctatcaa gattgtggct gggatttgat ttcgtcagtg
     7021 aatacttatt caaaaaccat tttcccaacg tttgcagatg tcttacggac aatcagagaa
     7081 attatcgact cgagcgaata cgacaatgat aataagggag cctataaagg agctttgctg
     7141 acacgcttgg agtcactgac aacggggatt taccagttga tgtttacaga agatgagatt
     7201 tcatccgaga agttatttga tgaaaatgtt atcgtggatt tgagtcgtct gggttctagt
     7261 gagaccaaat cgctgataat gggtctcctc attttaaaaa tgcaagaata ccgaatggtt
     7321 tctagtcagg gtatgaatca gcagctccgc catgtgactg ttttagaaga ggcccacaat
     7381 ctcttgaaac gtacatcaac agaacaggca accgaatcta gtaatttact tggaaaaagt
     7441 gtggagatgt tgaccaatgc catcgctgag atgaggacat atggagaggg ctttattatc
     7501 gcagatcagt cgccaggtct cttagactta gctgttattc gtaataccaa taccaagatt
     7561 attttgcgct tacctgaata ttccgatagg gagttggttg gtaagtctgc taatctaaat
     7621 gaagaacaaa taaatgaatt ggccaaactg ccgaaaggtg tcgcagcagt ctatcaaaat
     7681 gaatggctgg aaccagtttt atgtaaggtg gcaaagtatg actcaactga aatggtattt
     7741 caacaaccaa cccaattagt aaggacagaa tcaccctatc accgcttggc tattttagaa
     7801 ttactgacta ctagcccaaa cctagatagc accttgtctt ttgaagaatt acaagaatta
     7861 actctagcag taggtcttga tagtttgact caagtaagaa tctttaactt cttacgaaca
     7921 acatccccag ataattttag tatgcatgaa ctggcgcaca ttctcgggaa agtataccca
     7981 gaattagtcg agaaaattcg gttgaaagca gaaaaagggt tagagccacc cgctttgaca
     8041 caggtacttc agcaggaaat tgacagtagt atacctgaga cgatcagtga gcaggccaga
     8101 cgggatttag tacagggctt gatgacttgt tattatttat ttgaactaaa agaccacaag
     8161 gccatgcagg attggttacg aaatggagac ttaatatgat agaaggattg aaaactgttg
     8221 cggaggcagt taagcctgtc gtaaatgaag ttggcaaacg agcgatagat gcctttgaaa
     8281 agccgataga ttcagataag cgattggaag ctgcatctga taataaaacc acttttcgct
     8341 atgatggtct gagcaagcct caagaatttc tagctcaagc ccaagggttt cccaaagaga
     8401 tagctaagga tatttacaat tctcaggaac tcaagcatta tatggacata ggaatgcgag
     8461 ctgtgcaatt tggacagaaa gaaaatgggg agccacgatt ttgtcttatt ccaaaagatt
     8521 tatcgtttga tagagttgta gactcacagg ggcgaaccaa cgcagagcga ttgcaaagtg
     8581 gattactacc gataaaggat ggtcaacctt tagaagttca ccatatcggt caaaaaaacg
     8641 gtggtcatta tgccttattg acgaaagaag aacacattaa gaatgggaat aaagaaatgt
     8701 tgcataagcc aggtaaatct gatgttgatc atggtttaga ttttgctaga gataagcgat
     8761 caattgctaa agtacttatg gaggaacaag tatgagtcag ttagtagata aaataaaagt
     8821 agtccaaggt ctttatagcg gtagccctgc tagtgagcaa gaagtggcag tggctgagag
     8881 taagcttcag ttgatatttc cagcagagta taaggactat ttgaaagagt atggggtgat
     8941 ttcattctat ggaacagaat ggaatggatt gaaaggagat acttggaccg atgtagttgc
     9001 aaccaccttg gaagcgcgta gtctgtatga aaattttcct aaagagaaat ttattttaga
     9061 ggatctacat tttgatgata tgcttgtttt agcggattcg actggtaaag tctttttgtg
     9121 gcacaatgga ttagaaaaag agattcattc ctcaattgcg tcctatctgg aagaatgtgt
     9181 agccagaaag gacaccccat gattcaacct attatgaaag atattttctt cctgcagcag
     9241 aagtctgagc ctgcgactca gctagatgtg caggtcggtc aggacttgca ggacacttta
     9301 gcagccaatg ctcatgcctg cgtgggcatg gcggccaaca tgattggcgt caaaaagcgg
     9361 attatcatcg tcaatatggg ttttaccaac ctggtcatgt acaatcccgt cctcatcagc
     9421 aaggccaagc cctatcagac agaagagggc tgcctgtcgc tggaaggtac tcgcccgacg
     9481 acacgctatc aggagattga agtggagttt tttgatgctt catggaaaaa gatcagccta
     9541 aagctgacag acttccaagc ccagattgtt cagcatgaac tagatcattt ggaagggatt
     9601 atcatctaaa tctaccgtca ggtagatttt tttgtataaa agtcaaaaaa ggtcaaacaa
     9661 aactattgac ttttactgac caatgatgta aaataagatt cgtaaggtaa agggccttac
     9721 aaattctttg aacaaaaggt cagtttaggt caaacaaaaa agtttgaccg acaaattgac
     9781 taaatggtca gtaaaagaca aacttctaag gaggttgcta tgaaagacag gattataccc
     9841 tattaactat ttttttatca caaaaaggtc agttttggtc aataaaaaca taacatgaaa
     9901 cgaggtaaaa actatgaaca acaatttcaa taactttaac aatatggacg acattttcaa
     9961 tcaactcatg ggcaacatgg gtggctacag cacagaacgt cgccgttatt ctatcaatgg
    10021 gcgtgaagtg acaccagaag aatttgctat gtaccgtcag actggtcgcc tgccacagac
    10081 agaagaagtg gctcaaacac aggctaaagg tcagataaag tcagacggaa ttcttgcaaa
    10141 acttggtcgc aatttgacac aagatgcgcg tgaaggtaag ttggatccag tcattggacg
    10201 aaacaaggaa atccaagaaa cctctgaaat cctagctcgc cgtacgaaaa ataatcctgt
    10261 tttggtcggt gatgctggtg tcggaaagac agcggtagta gaaggattgg ctcaagccat
    10321 tgtcaatggt gatgtgccag cagccattaa gaacaaggaa atcatctcca tcgacatttc
    10381 aggcttggag gctgggactc agtatcgtgg agcttttgag gaaaatgtgc agaatcttgt
    10441 ggatgaagtc aaaaaagctg gaaatatcat tctcttcttt gatgaaattc atcagatttt
    10501 gggagctggt agcactggcg gagactcagg ttccaagggt ttagcggata ttctcaaacc
    10561 agctttatcc cgtggggaat tgacggttat cggtgccact acacaggacg aataccgcaa
    10621 tactattcac aagaatgctg ctctggctcg tcgtttcaat gaagtcaagg tcaatgctcc
    10681 gtccgcagag gacacctacc agattttgaa agggattaag ccgctttatg aagcccacca
    10741 caatattgaa ttgccagatg aggttttgag agctgcggtt gattattccg tccaatatat
    10801 tccacaacgt agcttgcctg ataaggctat tgacctagtc gatgtgaccg ctgcacattt
    10861 ggctgcacaa catcctgtga cagatattca gaccttagaa gcagaaatgg ctgaggcaaa
    10921 acagttgcag ttggaagcag ctgaaaaaga ggattatgaa aaagccttga atgaaaaagt
    10981 ccgtattgat aagctacaaa aacagattga taatcatacg gagcaacaga aagtggtggc
    11041 gactgttaat gatgtggctc aggcggttga gcggatgaca ggaattccag tctctcaaat
    11101 gggagcttct gacattgaac gactcaagga attgaaaaat cgtctggcag caaacgttat
    11161 cggtcaagac gatgcggtgg aagctgtatc tcgtgccatt cgtcggaatc gtgcaggttt
    11221 tgatgatggc aaccgtccaa ttggttcctt cctctttgtt ggtccgacag gtgtgggtaa
    11281 gacagagttg gcaaaacagt tagcactaga cttgtttggt aacaaggatg ccattattcg
    11341 tttggatatg tctgaataca gcgatcggac agccgtttcc aaattaatcg gtaccacagc
    11401 tggctacatt ggctacgatg acaattccca tactcttacc gagcgcgtcc gccgcaatcc
    11461 gtactcaatc gttcttatgg atgagattga aaaagctgat ccacaagtga ttacccttct
    11521 cttgcaagtg ctagatgatg ggcatttgac tgatggacag ggcaaccaag ttaactttaa
    11581 aaataccatt attatcgcga cttctaatgc aggttttggt tatggaatgg cagaaggtga
    11641 agaaaatcaa gacatcatgg accgcatcgc accattcttc cgcccagagt ttctcaatcg
    11701 ttttaacgca gtcatcgagt tcaagcattt ggataaagat gatctcaaag ccattgtaga
    11761 attactcttg gcccaggtca ataataccct ggcgaagaaa ggcatccaat taacggtaac
    11821 ggaagctgcc aaagaattct tgatggaaga aggctatgac aaggccatgg gagcccgtcc
    11881 tctgcgccgt gtgattgaaa atcagattcg tgataaggtg acggatttct atttggatca
    11941 tgttgatgtc aaatatctgg aagcggatgt ggttgatgga agcatccaaa taaaagagca
    12001 aagctttgct taaaaatagt gaagaatttg aaaaatcgga tagaaatatc tgattttttc
    12061 ttttttgtta ttcgctaaca aatgctataa aataggcttt ctagagcaca ttaaaacttt
    12121 ttttataaaa tccttgacaa gtgcaaacgt ttgcgttaaa ctatattcgt aaccgacaga
    12181 aaggaaaacg tttttatgac aaatcgtacc agtggaattt tgatgcatat tacctcactt
    12241 ccaggtaagt ttggtattgg tacttttgga cagtctgcct atgattttgt agatttcttg
    12301 gtggaaacca agcaaaccta ctggcagatt ttaccactaa caactacaag ctatggagat
    12361 tctccttacc agtctttctc tgctattgca ggaaatacac acttgataga ctttgacctc
    12421 ttggttgaag atggcttatt ggcaacagaa gatttccaag atgtaaattt tggagataat
    12481 cctgaaaaag tagactatgc tcttatctat caagttcgtc gaccaatttt ggagaaggca
    12541 gttcaagcat ttttacaaga tgataagaag aaagctgctt ttctagagtt tgaaaaggct
    12601 aactcatctt ggttgacaga ttatgcggag ttcatggcta tcaaggaata ctttggtaat
    12661 aaagctctcc aagaatggga agataaaaaa gttgtagctc gcaatgagga agctcttgat
    12721 aagtaccgct tagaattggc aaatcaaatc gactactaca aagtcacaca gtatttcttc
    12781 ttcagccaat ggaaacaatt gaaagaatat gccaacaaac accacatcaa aatcatcgga
    12841 gatatgccaa tctatgtttc tgctgatagc gttgaagtgt ggacaaaacc ccaactattc
    12901 aaattggaca gtgaacgcaa gccgctttat gtagcaggtg taccagctga taacttctcg
    12961 gcagatggtc aattatgggg aaatcctatt tacgattggc cagaacatga aaaaacaggc
    13021 tataactggt ggatttatcg tatccatgaa agtttcaaac tttatgatgt ccttcggatt
    13081 gaccatttca aaggtttctc agacttctgg caagttgatg gtaaggcaga ggtggcaaaa
    13141 gttggaactt gggaaccagg tcctggctac aatctcttca aggctgtcaa agaaacactt
    13201 ggagaccttc caatcattgc agaagacctt ggaaacattg acgctaaagc tcgcaaattg
    13261 cttgcggatt gtggctatcc aggcatgaaa atcttagaat ttggtttctt tgatgtaaca
    13321 ggtaagagta tcgatgctcc acaccgttgc attccaaatt cagttgccta cactggaact
    13381 cacgataatg aggttgtcaa tggctggtac aacaatcttg atccagaaca acaagaatac
    13441 gtggatgcct acagcaaccg taagccgatt gaaaaagtta gccaagctat gctccgtatg
    13501 ctgtttgcaa cagtgagtga tacagctatc gcaaccatgc aagacgtcct agacttggga
    13561 gaagaaagtc gaatgaatat gccgtcaact atcggtggaa actgggaatg gcgcatgaaa
    13621 gctgaagact tgacccaaga acgcaaagac ttcttgacaa aaatgacatt actataccaa
    13681 cgaggaaatg aaaaccatga ctaaatttac aacatttgca gaaacaaata cttcgaagaa
    13741 attagctgat ttgacaaatg aagaaatcta tcttcaactg ttgaactatg taaaagatgc
    13801 agcagcttca aaaccaaaaa acacaggaaa acgtaaagtt tactatatct cagctgagtt
    13861 ccttatcggt aaactcttgt caaacaactt gattaacttg ggtgtgtata aagacgttca
    13921 agcagaattg gcagcagctg gtaaatcatt ggcgcaggtt gaagatgttg aaccagaacc
    13981 atcacttggt aacggtggtt tgggacgtct agcttcatgt ttcgttgatt ctatgtcaac
    14041 acttgctatc aacggtgaag gtgttggtct gaactaccac tgtggtcttt tccgccaagt
    14101 atttaagaaa aatgagcaag aagcagagcc aaacttctgg attgaaaatg attcttggtt
    14161 gattccaaca actatcagct atgatgttcc attcaaaaac ttcactttga aatcaaaatt
    14221 ggatcgtctt gatattcttg gctataaaaa agagactaag aactacctca atttgtttga
    14281 tattgagtca gtaaactatg acttgattac agacggtatt tcatttgaca agactgatat
    14341 taaagaaaac ttgacactct tcttgtaccc agatgattct gataagaatg gtgaattgct
    14401 ccgtatctac caacaatatt tcatggtatc aaatgctgct caacttttga ttgatgaagc
    14461 aattgagcgc ggttcaaact tgcatgactt ggctgactac gcttatgtgc aaatcaacga
    14521 tactcaccca tcaatggtga ttcctgagtt gatccgtctt ttgactgaaa agcatggtat
    14581 tgaatttgcg gaagcagttg ccatcgttaa gaatatgact ggttacacaa accacactat
    14641 cttggcggaa gcacttgaaa aatggccact tgagttcctt gaagaagtgg tgccacactt
    14701 ggttgatatc atcaaagaat tggatgccct tattcgtgca gaaattaaag acccagcagt
    14761 ccaaatcatt gatgaatcag gtcgtgtaca catggctcac atggatatcc acttctctaa
    14821 ctcagtgaac ggtgtagctg cgcttcacac agaaatcctc aaaaactctg aattgaaagc
    14881 tttctacgag ctttatccag aaaaattcaa caataaaaca aacggtatca ctttccgccg
    14941 ttggttggaa tttgccaacc aagaccttgc tgattacatc aaagaattga ttggcgatga
    15001 atacttgaca gatgcgacta aacttgaaaa attgcttgcc tttgctgatg acaaggaagt
    15061 tcatgctaag ttggctgaaa tcaagttcaa caataagttg gctctcaaac gttaccttaa
    15121 agacaacaaa ggtatcgagc tggatgaaaa ttctattatt gatacacaaa tcaaacgttt
    15181 ccacgagtac aaacgccaac aaatgaatgc cttgtatgtt atccataaat accttgaaat
    15241 caagaatggt aaccttccga aacgtaaaat cactgttatc ttcggtggta aagcggcacc
    15301 tgcctacatc attgcacaag acatcattca cttgattctt tgcttgtcag agttgatcaa
    15361 caatgaccca gaagtaaata aatacctcaa tgttcacttg gtagaaaact acaatgtgac
    15421 agttgctgag aaactcatcc ctgcaacaga catttcagaa caaatctcat tggcttctaa
    15481 agaagcgtca ggtactggta acatgaaatt catgctcaac ggtgcattga cacttggtac
    15541 aatggatggt gccaacgttg agattgctga gttggctggt atggataaca tctatacatt
    15601 tggtaaagat tcagatacca tcatcgactt gtacgataag gctggatatg tatctgcgga
    15661 ctactacaat ggcgatgcca atatcaaacg tgcagttgac tttatcgtta gcgatgaggt
    15721 aaaagcactt ggtaacgaag aacgtcttgg ccgtctgcac catgaattga tttcgaaaga
    15781 ctggttcatg accttgattg acttggctga atacattgaa gtaaaagaac aagtctttgc
    15841 agactacgaa gatcaagatt catggaacaa gaaagttgtt cataacattg ccaaagctgg
    15901 attcttctca tctgaccgta cgattgaaca gtacaatgaa gatatttggc acagtaacta
    15961 attgaattcc aacaattagt aggaaagttg attgaaccac tccaaaactt atcagatcaa
    16021 ttcttcctat gtgttgaaga ataaaaaccg accagttttt accattattg gtactctcct
    16081 tagtatataa atgcaaagaa tgtctctgca aaagcagaga cattcttttt ataactataa
    16141 aattctagaa gttttgtaca cttgatcaaa aaaatcgaaa gtttcctttt accgtttcgc
    16201 cattgataca aagctaactt tgtctggacg gtaactaatt gttccatact ggaaagcttg
    16261 accatttgaa agataggtga tgctagtgac cacgacgacc atgtcatagt ctcctaagtc
    16321 catcaattgt ttttcttctt cgtttgcaaa acggaaggaa atttcacgtc tggaatgaga
    16381 aattgttaaa tggagttctt cttctaagta gcggtaaata gagctttcgg caatttcttt
    16441 gctgagataa gggacgaccc tacggtcaaa ataggaaatg tcatattcca accgctcacc
    16501 gtcaattgtc cgtacccgac tcactcgata gaaatctacc ttatcatcaa cttcgaaagt
    16561 tgacattaaa tcttcttgac cttgaataat ataaagcgaa gtaagctggg tctgaatttg
    16621 gtgctgtgat cttttgttca attcgcccgc tgttttaatt tcagaaagat attggtcctt
    16681 cattagacca tgttcgataa caatagaaga tttcccctgt ttcttttgaa tataaccatc
    16741 catttcaaga agagatagtg ctttgcgaat ggtgtccttg gagtaggaat acacttccat
    16801 taattcattt tctgtcggta gggcctgtcc agttgaccaa acctgctctt cgattttttt
    16861 cttaatatct tgataaactt ttttatactt actcatagtt tcctgtcttt ctacccatta
    16921 gtgtatcata aaagagctag aaaggggcaa tacatctatt ttatttagta gaatatacaa
    16981 cttttacgta aaagtttaaa atattacgga aaagctattg actaatgcaa acgtttacgc
    17041 tatactattc ctataaaaga aaacggttac gcattttcag agagaggggg agcaatgaaa
    17101 ttactaacaa ttaatgtcca cgcctggtta gaagaaaggc aggatgaaaa actagatgtt
    17161 ttagcccaaa caatagctga aaaggcttat gatgtcatcg ctcttcaaga ggtcaatcag
    17221 ctcataactg ctgatttggt aacgaaagac ttgaaggcgg ataattatgg cttgatttta
    17281 ttagaaaaat taagaacctt gggacaattt gactattcat attattggag caactcacat
    17341 atcggctacg ataagtacga agaagggatt gcctttctta ccaagttgcc agtttatgaa
    17401 gtggatcaat tttattgtag tcagaataaa tctattgatt ccatcctatc acgaaaaatt
    17461 atgggattga cggtcttcta tcaagaccag ttgatcgacc tgtattcttg tcacatcaat
    17521 cttccaggga gtgaagagga agaccagctt gataacattc gtacgattgt ggaacggact
    17581 ggcaatagac gttttaagat tcttatggga gattttaata ccgatgcctt ctcagatcga
    17641 gaggcctacg aagcgattac agagctcggt ctttatgatt catataatct agcgatggaa
    17701 aaagaccagg ggattacggt tgaaaaggct atcgatggct gggctggtca cagtcaggaa
    17761 aaacgattgg attacatttt cttaaatcag aaaaaggaag ttttatccag cttagtgatt
    17821 ttcaatggag agaatcgtcc gattatttca gaccattttg gtgtggaagt tgaaattaat
    17881 gtataaaatg gcacagagcc aaaaaataaa ggagaaaaaa tgaaaaaatt tcttagtttc
    17941 gaattttggc aaaaattcgg taagtgttta atggtcgtga ttgcagttat gcctgcagca
    18001 ggtctgatgg tttctatcgg aaactctatt ccgttaatca gcccagaatc agaactcttg
    18061 attcgtattg ggaatatcat tgcccaaatc ggttggggga ttatcggaaa ccttcacttg
    18121 ctctttgcct tggctatcgg tggaagctgg gctaaggaaa aggctggtgg tgccttctca
    18181 gcaggtcttg ccttcatcct tattaacttg attacaggtc acttctttgg agtgacgact
    18241 gacatgcttg cagatgcagc agcaaccgta accactgttt ttggaacaga gattccagtt
    18301 tcaggctact tcgtcaacat cttgggtcag cctgctctga acatgggtgt cttcgttggt
    18361 atcatcgctg gttttgtagg ggcaacaacc tataacaaat actacaatta ccgcaaatta
    18421 cctgatgttt tgaccttctt taacggtaaa cgctttgtac catttgtggt tatctatcgc
    18481 tcagttcttg tagcgctagg attagctatc ttttggccag ttgttcaaac aggaatcaac
    18541 agctttggta aatggattgc aagctcacag gatacagcac caattcttgc accttttgtt
    18601 tatggtacct tggaacgttt gcttcttcca tttggtttgc accacatgtt gaccattcca
    18661 atgaactata catcacttgg tggcacctat gacatcttga caggtgcaca agcaggtaca
    18721 caagtatttg gacaagatcc gctctggttg gcttggatta cagacttgat caacctcaaa
    18781 gatgctggcg atatggctca gtacaatgac cttcttgcaa acattactcc agcccgtttc
    18841 aaagttggtc aaatgattgg ttcatcaggg attttgatgg gattgactta cgctatgtac
    18901 cgcaatgtgg atgaagataa aaaacataag tacaaaggta tgtttatttc ttcagcactt
    18961 gccgtattct tgacaggtgt aacagaacca attgagttta tgttcatgtt tgcagcaatg
    19021 ccactctatg tcgtttatgc ttttgtacaa ggtgcggctt ttgccatggc tgacattgtc
    19081 aacttgcgta tgcactcatt tggtaatatc gaattcctta cacgtacacc gatggcgatc
    19141 aaagctggta tcggtatgga tgttattaac tttatctggg taacagccct ctttgcggtt
    19201 ggtatgtact tcattgccaa ctttatgatt aagaaattca acctagcaac agctggacgc
    19261 aatggcaact atgatacaga aacaacggat gtggtttcaa actcaaacgt agatactgcg
    19321 gatgccaatt cacaagtggt tcaaatcatc aacttgcttg gtggtcgtga taatatcgca
    19381 gatgtggatg cttgtatgac tcgtcttcgc gttagtgtta aagatgtggc acaggttgga
    19441 gatgaaaatg cttggaaaca ggctggtgct atgggcttga ttatcaaaga ctcaggtgtt
    19501 caagcagtct acggaccaaa agcagatgtt ctcaaatcag acattcaaga cttgctagaa
    19561 tctggcgtag ccattcctcg tacggaaatt gttgcgacag aagaagttgc tcctgagact
    19621 cagttcaaag gtgtgacgga gacagtctac tctgttgctg aagggcaagc cattgccatc
    19681 acagaagtga aagatccggt cttctcacaa aaaatgatgg gcgacggtta tgcagttgag
    19741 cctagctcag gcaatgttta cgcaccagtt tcaggtattg taaccagtgt cttcccaacc
    19801 aaacacgctg tcggtatttt gtctgacaag ggtgtagaag ttttagttca cattggttta
    19861 gacacagttg cactaaacgg tgctccattc tcaactaagg taacagatgg tcaacgtgtt
    19921 gaagcagggg atttgctcct tgtcgcagat ttggaagcca ttcgctcagc aggacgtgaa
    19981 acaactatcg tcgttgcctt cacaaacaca gctgaaatca aatctgtcag ccttgaaaat
    20041 cttggacagg tcagtcaaga tagccaagtt gcgacagtag agttgtaaaa agtaaaaaag
    20101 attgaaaaga tgattgcagt caactctttt caatcttttt cttttggata gtatgccatc
    20161 agtatttttc taatttcttc gcttcttttt tacctttttc agcgatatgg aggaaataaa
    20221 tagaccaagc aaggaaaaat aagggaataa tgccacttct aaacaatgcg aatggggttt
    20281 caaagagaaa accaaaccaa aaactggtac cagttcgttc ccatagtcct ggagttaggt
    20341 accaggattt aggattccaa agtgtgtatc cattttggag tccaacttgg taatggataa
    20401 aaaataaagt cagaaataat ccgaaatagg agtaggcata attttggtag cgtgaataga
    20461 atgctttttt cgattcggta tcagaaaaaa tttctgtgct tgaagtttcg attgtttgtt
    20521 gaaaataatg gatgccacat ctacgactac cttgtatagg ttgccaacca cagtcttcaa
    20581 atagagagag gtaatttgaa tattctcctt ttgcaatatg ttcatgaaaa tcaaggcgta
    20641 cgggatgagg ggttcgacta catttttcaa aatgataggt tgctgtccac ggagttactt
    20701 tgacaagctg ataaccttcg gattgaatcg aattgatcca atgttcttcc tcttgtaaac
    20761 tggtgaataa tttgtgtctt atcatggctt cctccttaaa aacctaattc tttggcaata
    20821 tgatgtagtt tttgaatacg ctgtgtttcc agtttaataa tctcttggcc cgttgctgtt
    20881 acttgataga cttttcttct tttatcggaa cttggaacag aacaaatcca ttttagtttc
    20941 aaaagattct caatcgctcc atacatggtt cctgcagcga ttttcacatc accatcactc
    21001 atatcctcta ctttttgcat gatatggtag ccatgggcag gttccaagag ggctaataga
    21061 atatagtagg ttgtctccgt taaggggaga tgcttgttcc ttttcatttg gtttctccta
    21121 tgtag
//
LOCUS       DBNFCO010000033        21016 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.033, whole genome shotgun sequence.
ACCESSION   DBNFCO010000033 DBNFCO010000000
VERSION     DBNFCO010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 21016)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21016)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21016
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.033"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(101..790)
                     /gene="thiE"
                     /locus_tag="AC1PIV_001021"
     CDS             complement(101..790)
                     /gene="thiE"
                     /locus_tag="AC1PIV_001021"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HIP6612053.1"
                     /translation="MNRKMLQVYFICGTSDCPKGKFLDVLEKALQAGITCFQFREKGE
                     QGLTGADKLLLAKQVQHLCHRYQVPLIINDDVELARAIDADGIHLGQEDLSVVEARQL
                     FPGKIIGLSVGTKEEYLNSPIDLVDYIGSGPVFPTLSKDDASPAIGMDGLKQLRKLNS
                     DIPMVAIGGLSAKDCKEVLQAGADGIAVISAISHAEDPYKATKILVDGMQAMILKFNQ
                     VESNKQILKNP"
     gene            complement(783..1568)
                     /gene="thiM"
                     /locus_tag="AC1PIV_001022"
     CDS             complement(783..1568)
                     /gene="thiM"
                     /locus_tag="AC1PIV_001022"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004417 - hydroxyethylthiazole kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HIP6612054.1"
                     /translation="MYLEKLRSQNPLTICITNDVVKNFTANGLLALGASPAMSEYPED
                     LEDLLPYTKGLLINTGTLTNETWELYKSALDIAEKYGVPTVLDPVAAGAGAYRKKVTL
                     DLLHHHTISLVRGNAGEIAALIGESIETKGVDSAQIDNVGELALRANQQLGIPVVITG
                     KKDAVAVNHQVRILENGSELMPLVTGTGCLLGAVLAAFIHLADEDSLLDCLEEVLSAY
                     SIAGEMAEQKTSLPGTFQIEFINSLYAIQSEEVEENKKVIHYE"
     gene            complement(1573..2370)
                     /gene="thiD"
                     /locus_tag="AC1PIV_001023"
     CDS             complement(1573..2370)
                     /gene="thiD"
                     /locus_tag="AC1PIV_001023"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HIP6612055.1"
                     /translation="MTSLHVALSIAGTDPTGGAGIMADLKSFQARSVYGMAVVTSVVA
                     QNTKGVQLIRHLDQEILEEQLKSVFQDIVPDAIKTGMLAQVETIELVASYLAKQKCPY
                     VLDPVMVATSGDRLIEEDAIKALKTKLLPLATIITPNLPEAEVLVGRTLKSENDIMNA
                     GRWIRKELGVKNVVIKGGHLAKAASDYLFLEDGEISVISAARISTNHTHGTGCTYAAV
                     ITAELAKGRTVAKAVETAKRFITEAIQTALELGHGNGPVNHTTYRGE"
     gene            complement(2367..3014)
                     /locus_tag="AC1PIV_001024"
     CDS             complement(2367..3014)
                     /locus_tag="AC1PIV_001024"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HIP6612056.1"
                     /translation="MNKMVIWFDLDGVIFDSYGVWDQVVQGILKHHGVAYTQQIREEL
                     WRIPMEDVNGYLLQLVENSLDENELERQKMNQLQSLYRDISLMDGVHELLSTLKAKGA
                     VMYAVTSNYLELAELGLSSHHLSNYFVKLFSSLNLFGSDKNREFYQFILHQERIDPAN
                     IVMVEDNKNNLCIGHELGIAGVYIEHPNSPFSDENTGIVSIKQLSELIPILEDRK"
     regulatory      complement(3349..3438)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(3501..5780)
                     /gene="pcrA"
                     /locus_tag="AC1PIV_001025"
     CDS             complement(3501..5780)
                     /gene="pcrA"
                     /locus_tag="AC1PIV_001025"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HIP6612057.1"
                     /translation="MNPLLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKMVNPWNILAITFTNKAAREMKERAYALNPATQACLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRSLMKRILKNLNLDPKKWSERSILGTISNAKNDLIDDKAFEAQA
                     GDLYTQIVAKCYTAYQKELRQSEAVDFDDLIMLTLRLFDQNPEVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPESKVVL
                     LEENYRSTKNVLQAANEVIENNRNRRPKKLWTQNAQGDLITYYRARDENDEAIFVAGQ
                     IDQLHREGKAYKDFTVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDVISY
                     LNIIANPSDNISYERIVNEPKRGVGPGTVDKLRDFATSHSMSLLEASQDIMLSPVKGK
                     AAQAVFDLANLLYNLRNQLDNLTVTQVVEAVLNQTGYIDALAAQNTLEANARIENIQE
                     FLSVTKNFDEKDVEEEETGLDKLTRFLLDLALIADTDDGDTESSEVTLMTLHAAKGLE
                     FPVVFLIGMEENVFPLSRAAEEEDELEEERRLAYVGITRAEQTLYLTNANSRLLFGRT
                     NYNQPSRFIREISSDLLDYQGLARPANTSFKASYVNGRATQFGQGMSLQQALQSRKAS
                     VQPSAKLGGSMPFASSNQSSSSGTNWSVGDIAVHKKWGRGTVLEVSGSGSNQELKINF
                     PDMGLKKVLASLAPISKED"
     gene            complement(6069..7436)
                     /gene="nox"
                     /locus_tag="AC1PIV_001026"
     CDS             complement(6069..7436)
                     /gene="nox"
                     /locus_tag="AC1PIV_001026"
                     /EC_number="1.6.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="H2O-forming NADH oxidase"
                     /protein_id="HIP6612058.1"
                     /translation="MAKIVVVGANHAGTAAIKTMLTNYGQENEIVVFDQNSNISFLGC
                     GMALWIGEQIGGPEGLFYSNKEELESLGATVYMESPVTNIDYDAKTVTALVNGQEHVE
                     SFEKLLFATGSQPILPPIKGAEIKEGSLEFEATLENLQFVKLYQNSADVIEKLKNKDI
                     NRVAVVGAGYIGVELAEAFQRKGKEVVLIDVVDTCLAGYYDRDLSDLMAKNLEEHGIK
                     LAFGETVKEVAGNGKVEKIITDKNEYDVDMVILAVGFRPNTALAGEGIERFRNGAFLV
                     NKRQETSIPGVYAIGDCATIYDNATGDTSYIALASNAVRTGIVAAHNICGTDLEGIGV
                     QGSNGISIYGLNLVSTGLTLEKATRLGLNAAVTEVTDNQKPEFMEHGNFPVTIKIVYD
                     KDSRRILGAQMAAREDISLGIHLFSLAIQEGVTIEKLALTDLFFLPHFNKPYNYITVA
                     ALGAE"
     gene            complement(7621..7959)
                     /locus_tag="AC1PIV_001027"
     CDS             complement(7621..7959)
                     /locus_tag="AC1PIV_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP cone domain-containing protein"
                     /protein_id="HIP6612059.1"
                     /translation="MQVIKRSGEIVEFDPDKIYQAIIKAAQTVYVIDETWRKNLAQVT
                     KKVVLDLEEAHTERPTISMVQSQVEHRLLDAGYISIAEHYISYRLQRDLERNGYGDKI
                     IVHLRFEQVR"
     gene            8126..9916
                     /gene="pepF"
                     /locus_tag="AC1PIV_001028"
     CDS             8126..9916
                     /gene="pepF"
                     /locus_tag="AC1PIV_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HIP6612060.1"
                     /translation="MTNAMPKRQEIDVQLTWDTDILFPTPDNYKENLAAYAKQVTAFE
                     SNYKGKLTDKDTIVSALTEYEKIVILDSRLSHYAFLPLEVDKMNTELASLANEYDLVS
                     AKARPQRDFLYSELGQLDEAFLLELKEEQPQLAAFFDAILRDKPHQLHPLQEELLSNF
                     APTFGQPYNNYGVTKFEDMTFENFEANGETLGNSYVLFENDYELSHDTEIRRNSAAGF
                     YSTLKKYKNTTAATYLSHIKNEQIEARLRGFDNTIDFLLHSQNVSRDLFDRQIDVIMK
                     ELAPHMRRYVKLVAKAHGLDKITHADLKISLPSEYNQRITPEESKQFLIDCLGILGED
                     YVKMIEQSFDERWIDFAQNEGKATGGFCATLYDGPSYILLSWTGLMNEVLVLAHELGH
                     AGHFQLAKKQSVLSYDPSLYFIEAPSTANEVLTCNTLLKNNQDPGFQAYLISELISRT
                     YFHNMVTHLLEAAFQREVYTRLDNEEYLNGDILCQIKLDVIKEFWGEDFEIGDDAGLI
                     WMRQPHYYIGLYPYTYSAGLTIGTAMAKQLEEHPEEVVEKWLETLSLGASLSAQDLAK
                     HAGVDVSTDQPLKETIAYVGSLVDKLETLI"
     gene            complement(9941..10333)
                     /locus_tag="AC1PIV_001029"
     CDS             complement(9941..10333)
                     /locus_tag="AC1PIV_001029"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HIP6612061.1"
                     /translation="MRLSAFLDFWQDLDIRDYRQITFVGFSNGANFIMGLLAKQSNLA
                     DNYILLHPSALDYAFPMENSRAEILFTLGQNDQLVDQVALEHLVDDWQASAFPRANLV
                     RFDKGHFLSQDELTYVGNWYQERIDKKT"
     gene            complement(10556..11506)
                     /locus_tag="AC1PIV_001030"
     CDS             complement(10556..11506)
                     /locus_tag="AC1PIV_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,6-dichloro-p-hydroquinone 1,2-dioxygenase"
                     /protein_id="HIP6612062.1"
                     /translation="MNNTGIHHISSLVGNIHQAYHFYHHILGLKLTLKTVNQEDSSMY
                     HLFFGDEEGRYGTEFTIFDMPNHPNHRNGTNRLERTVFLVKNFEALEFWQKRLTEFEV
                     ENEGIQAFGNGHILNFQDEDGQLLGLTYHNAIGEMFPYKIDEIPSEYAILGIASLHMR
                     IREEKALLSLLTETFGFVEESRFVFEDKIVISLLFDNTFQHRLYLILDQESPISVMGV
                     GAIHHIAFGVLDESDLEDLISRLNLINRPHSGIINRDFIHSLYFRAPNYLMFEVATMT
                     GERESEMPAQNEELDQVDLFLPSFFEEDRQEIEKNLSQRY"
     gene            complement(11638..12345)
                     /locus_tag="AC1PIV_001031"
     CDS             complement(11638..12345)
                     /locus_tag="AC1PIV_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HIP6612063.1"
                     /translation="MTNELIGEVLGTTLLVLLGNGVVAGVVLDKSKAKDAGWIVITIG
                     WGLAVAMAAFVSGLLGTAHLNPAVSIAMAFAGNLPWASVVPYILAQFIGAFIGSILVY
                     LMYKDHYDATEDTGAVLATFSTGPAIRNLVSNTISEAIGTFVLVLGLLAFGQYDFPTG
                     IGTLIVGGLIVSLGVSLGGPTGYALNPARDLGPRIMHAILPLKHKGDSDWGYAWVPVV
                     GPIIGGLLAALLYGLIF"
     gene            complement(12359..14188)
                     /gene="glpO"
                     /locus_tag="AC1PIV_001032"
     CDS             complement(12359..14188)
                     /gene="glpO"
                     /locus_tag="AC1PIV_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004368 - glycerol-3-phosphate
                     dehydrogenase (quinone) activity [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HIP6612064.1"
                     /translation="MEFSKETRRLAIERMQDRQLDLLIIGGGITGAGVALQAAASGME
                     TALIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQNIAPHIPKPDP
                     MLLPVYDEPGSTFSLFRLKVAMDLYDLLAGVNNTDMANKVLTREEVLEREPNLKQEGL
                     IGGGVYLDFRNNDARLVIENIKRAAKDGALIASRAKAEKFIKDDAGKVVGIVARDLLT
                     DRTFEIRARLVINTTGPWSDEVRNLGGEGSGVLQMRPTKGVHLVVDSSRLSVPQPTYF
                     DTGHADGRMVFVLPRENKTYFGTTDTDYTGDLANPMVTQEDVDYLLDIVNNRFPEANL
                     TLDDIESGWAGLRPLLSGNGASDYNGGNNGKLSDDSFNSLIETVKGYMNNEKTRDDVE
                     HDLTHLEGSVSEKHLDPSAVSRGSALDRDDNGLLTLAGGKITDFRKIAEGAIEKVADI
                     LKEEHGRSFKLINSKTYPVSGGELNPANVAEEIEHLAQLGVKKGLLYDDALYLANLYG
                     SNAPKVFVLNHKVEAVSGLNKRDLLSLHYAMKEEMTLTAVDYLLRRTNYMLFMREQLD
                     AVALEIIKEMAAYYAWSEEEVAQQKQLLADTLVKNDLTYLKEK"
     gene            complement(14264..15778)
                     /gene="glpK"
                     /locus_tag="AC1PIV_001033"
     CDS             complement(14264..15778)
                     /gene="glpK"
                     /locus_tag="AC1PIV_001033"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014917235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HIP6612065.1"
                     /translation="MSTEKYIMAIDQGTTSSRAIIFNKKGEKVGSYQKEFTQIFPKPG
                     WVEHNANEIWNSVQSVIAGSFIESGVRPDQIEGIGITNQRETTVVWDKETGLPIYNAV
                     VWQSRQTAHIADQLKADGHADMIHQKTGLVVDAYFSATKVRWILDQVPGAQERAEKGE
                     ILFGTIDTWLVWKLTDGKCHVTDYSNAARTMLYNIEELKWDDEILSLLNIPKAMLPEV
                     RSNSEVYGTTAPFHFYGAEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIVMNT
                     GEEMQLSQNNLLTTIGYGIGGKVYYALEGSIFIAGSAVQWLRDSMRMVTTSPESEELA
                     RKSTSNDEVYVVPAFTGLGAPYWNSDARGSVFGLTRGTTKEDFVKATLQSIAYQVRDV
                     IDTMQLDTGIDISVLKVDGGAAMNSLLMQFQADILGIEIARAQNLETTALGAAFLAGL
                     AVGFWKDLDELKELNAVGQSFQPTMNEARKEQLYKGWKKAVAATQLFAEVDEEQ"
     gene            complement(16008..17471)
                     /locus_tag="AC1PIV_001034"
     CDS             complement(16008..17471)
                     /locus_tag="AC1PIV_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIP6612066.1"
                     /translation="MRIDSLLEKRELAIYQLLLYLEDRKEAPSLKDICHYLELSKLTL
                     FRYIVSFNEEAEVTDLGLSFQLEDEKVFLKKKASLSLHRILDYLCQTSTKYQIIVYLS
                     DKEEVSIQQLAQELLISEATLNRHLASLNQILAEFGIGIKSGRLKGSELQIRYFLHQM
                     LSLTTTRAELQEEFMLGKIEALLPVFERFYQSPLNPKQAHRLLLWLMISQQRSRLRQL
                     DFKHLYKLMEPYQEHKFYRRLRKMYFTLSQQQSTSFQEGEIMALFAFLFSHFILVPHQ
                     LEQVLGFGGPIMEATSLALQKLRLYFEGNLPVSEEALYHLNQIMSQLYFFYSSVELEE
                     VEASSFYSEAEDLLKDVYKSVFHRKVDKKIRNSYLTNIADLYIYFGQVQPIQVKVAFA
                     SSLHEVLSYPLLLQLREKLEGNRQVLIEPYQAGYDYDLIITDYLENTSIPVYCLGNRL
                     KIQDIVQLKAWIQDIYHQKSCQSEIMATKTSFPIEHR"
     gene            complement(17461..18813)
                     /locus_tag="AC1PIV_001035"
     CDS             complement(17461..18813)
                     /locus_tag="AC1PIV_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HIP6612067.1"
                     /translation="MNIVIIGASFAGLSAALECRKLYQNAQITLIDREKDVAYFPNTL
                     NWKVAGKISGWEEAKISLFSEVQHAAISCLFETECLAVYPEMRKVKIRHHQDIGDIIY
                     DRLILAMGASQTWEWGTEELQDYLIRSKTLSQAQASLEKLTNAKTVAVIGAGQIGLES
                     LDALSQLDLNLHVFEAQDSLLAKYVDEDMIAPIRQEMKKRGIQLHLSETVNQITIDTQ
                     EEQLVCHTVTGNYPADLVLPSTNLTPNIQLVKDRLKVIAEGTVWVDEFLETSQENIFA
                     VGDLVSLPVDYFGQAYLPMIHHAIMTGRMAARNLQKRIAPIKRAQRIVSSHVFGYYIT
                     SLGLTESEASLWLESKSIRIRRSYSQWEPTLVDFKLIVEETSGRIIGGQLVSTADYIE
                     QMDVLSLAISKDLTVFDLVEHSWLCLPGNTPLVPFIVEAAQEYIRQFYQVDGEGVYAD
                     "
     gene            complement(19028..19963)
                     /gene="dapA"
                     /locus_tag="AC1PIV_001036"
     CDS             complement(19028..19963)
                     /gene="dapA"
                     /locus_tag="AC1PIV_001036"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HIP6612068.1"
                     /translation="MSIQDLRDVKIITAMITPFKEDGSINFEVLPELIEHLLSHHTEG
                     ILLAGTTAESPTLTHEEELELFGAVQKIVNGRVPLIAGIGTNDTRDSIEFAKEVAAFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVEMTPETMLRLAE
                     HPNIIGVKECTSLANMAYLIEHKPEDFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMYEMFTAIEQQDIRTAAAIQRKFIPKVNALFSYPSPAPVKAVLNYLGFEVGPLRLPL
                     VPCPEEDAKRIIKVVVDGDYEATKATVTGVVRPDY"
     gene            complement(20036..>21016)
                     /locus_tag="AC1PIV_001037"
     CDS             complement(20036..>21016)
                     /locus_tag="AC1PIV_001037"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HIP6612069.1"
                     /translation="RFLASARSAGKTLQFKGQDIVIEETTETAFEGVDIALFSAGGST
                     SAKYAPYAVKAGAVVVDNTSYFRQNPDVPLVVPEVNAHALDAHNGIIACPNCSTIQMM
                     VALEPVRQKWGLERIIVSTYQAVSGAGMGAILETQAQLRSVLNDGVEPKAVEANILPS
                     GGDKKHYPIGFNAIPQIDLFTENDYTYEEMKMTKETKKIMEDDSIAVSATCVRIPVLS
                     AHSESVYIETKEIAPIDEVKAAIASFPGAVLEDDVANQIYPQAINAVGSRDTFVGRIR
                     KDLDKENGIHMWVVSDNLLKGAAWNSVQIAETLHERGLVRPTAELKFELK"
BASE COUNT         5997 a         4709 c         4099 g         6211 t
ORIGIN      
        1 tttaaggctt ttgatttttg taaagtagaa aaactatttt tcttgccact aatatcaact
       61 aagaattcgt tttaatatca aatgaaaaga cccaaattga ttagggattt tttagtattt
      121 gtttattaga ttctacttga ttaaatttta aaatcattgc ttgcatccca tccaccaata
      181 tcttggttgc tttgtagggg tcttcagcat gggaaatggc tgagataaca gctatgccat
      241 ctgcacctgc ttggagaact tccttacaat ctttagcaga taaccctcct atcgcaacca
      301 tgggaatatc ggaattgagt ttccttaatt gctttaatcc atccattcca atggctgggc
      361 tagcatcatc cttagataga gtaggaaaaa caggtccgct tccgatataa tcaactagat
      421 caataggcga attgaggtat tcttcttttg ttccaactga tagtccaatt attttccctg
      481 ggaagagctg tctcgcttct actactgaca aatcttcctg tccaaggtgt attccatcag
      541 catcaatggc acgtgctaac tcaacatcat cattaatgat taatggaacc tgatagcggt
      601 gacacaggtg ttgaacttgt tttgccaaca gtagtttatc agcccctgtt aaaccttgct
      661 cacctttttc acgaaattga aaacaagtga ttcctgcctg caatgccttt tccagtacat
      721 ccaaaaattt gccttttgga caatctgacg tgccacaaat aaagtaaact tgaagcattt
      781 ttctattcat aatgaatgac ctttttattt tcttcaacct cttctgattg gattgcatag
      841 aggctattta taaactcaat ctggaaggtt cctggtagtg aggttttctg ctctgccatt
      901 tctccagcga tcgaataagc cgataggacc tcttccaaac aatccaataa tgaatcctca
      961 tcagccaggt gaataaaggc agccagaact gctcccagca ggcatcctgt ccctgtcact
     1021 agtggcatta actcactacc attttccaaa atccgaacct gatgattcac agcgacagca
     1081 tctttttttc ctgtaatcac aacaggaatt cctaattgtt ggttggctct gagagcaagt
     1141 tcacctacat tgtcaatctg agcagaatct acccctttcg tttcaatact ttcaccaatc
     1201 aaggctgcaa tttctcctgc attcccacga acgagtgaaa tagtatgatg atgtaacaga
     1261 tccaaggtaa ctttcttgcg ataggcacca gcacctgccg caacaggatc taagacagta
     1321 ggtacaccat atttctcagc aatatccaag gcagatttgt atagttccca agtttcattg
     1381 gtcaaggttc ctgtattaat caataacccc tttgtatagg gaagtagatc ctccaaatct
     1441 tctggatact cgctcattgc aggtgaggca ccgagagcaa gtaagccatt agctgtaaaa
     1501 tttttgacta catcattcgt aatacaaatg gtcaagggat tttgactacg taatttttcc
     1561 aaatacatct agttactctc ctctgtaggt ggtatgattg acaggaccat ttccatgccc
     1621 cagttctaga gcagtctgaa ttgcttctgt aataaatcgt ttggcagttt cgactgcttt
     1681 tgctactgtc cgacctttcg ccaactctgc agtaatgact gccgcgtagg tacaacctgt
     1741 accatgggta tggttcgtag aaatgcgtgc tgcactgatg acactaatct caccatcttc
     1801 taaaaataag tagtcagatg ccgcctttgc cagatgtcca cccttaatga ccacattttt
     1861 taccccaagt tctttccgaa tccaacggcc cgcattcatg atgtcatttt cacttttcag
     1921 tgttctaccg actagaactt ctgcttccgg tagattcggt gtaatgatgg tagcaagggg
     1981 cagtaatttt gttttcagcg ctttgattgc atcctcttca atcaaacggt ctccactcgt
     2041 tgcgaccata acaggatcca agacatatgg acacttctgt tttgcaagat agcttgcgac
     2101 aagctcaatg gtctcgactt gtgctaacat tccagttttt attgcatctg gaacaatgtc
     2161 ctgaaagaca cttttcaatt gttcttctaa aatttcctga tcaagatgac gaattagttg
     2221 cacccctttg gtattttgag caacgacact cgtcacgact gccataccat aaactgatct
     2281 agcctgaaag ctcttcaaat cagccataat gcctgctccg cctgttggat ctgttcctgc
     2341 tattgataat gctacatgta aagatgtcat tttctatcct ccaaaattgg tattaattca
     2401 cttaattgct tgatgctaac tatacctgta ttctcatcag aaaaagggga atttggatgt
     2461 tctatataaa ctcccgctat tcctaactca tgtccaatac aaagattgtt cttattatcc
     2521 tcgaccatta cgatattggc tggatctatc cgttcctgat gtaggatgaa ttggtaaaac
     2581 tccctatttt tatcgcttcc aaacagattc aaactgctaa atagtttcac aaaatagttt
     2641 gaaagatgat gggatgacaa tcctagttca gccagctcca gatagtttga agtgactgcg
     2701 tacatgactg caccttttgc cttcaatgta gataggagtt catgcacacc atccatcaag
     2761 gaaatatctc tatatagtga ttgcagttga ttcatttttt gcctttcaag ttcattctca
     2821 tctaaggaat tctccacaag ttgcaataaa tacccgttga catcttccat tggaatacgc
     2881 caaagttctt cccttatctg ctgggtataa gcaaccccgt gatgtttcaa aattccttga
     2941 accacctgat cccagacccc ataggaatca aagataacgc catcaaggtc aaaccaaatg
     3001 accattttgt tcatctatat ctcctttctc tttttctcgg tgaaaatgta aattgaaggg
     3061 gctaagggga tttgtgaaaa tactattaat tgtattagcc ttatcatcag tttcgccttg
     3121 tcgaactcta cgaaagtgac ttattgcgca tatcttattt ccatcgtagt atagcctcta
     3181 ggctggtcga gctacctgca ctcaattccg tatttctgag aactcttcat tcgacaatag
     3241 aaaaaactcc atctgatggt ttatcaaatg gagttacacc tacgatgatt gatgaccagt
     3301 aaatacagta ttctatacta gaatacaaat atagtacttg tcaacaaaat ttgttgatac
     3361 acatttccct tcggcagtcc taactgcatc aggttcgatg ggtataatct cagcctcttg
     3421 gcaccccaaa tgttctattc aattttacaa aaatacttta tcatattttc gagcttactg
     3481 caattatttt ttaactaaat ttaatcttct ttacttatcg gcgctaagct tgccaagact
     3541 tttttgagtc ccatatcagg gaaattgatt ttgagttctt gattgctgcc tgaacctgat
     3601 acttcaagga ctgttccgcg gccccatttc ttatggactg cgatgtcacc aactgaccag
     3661 ttggtgcctg agcttgacga ttggttgctt gatgcgaagg gcatactacc tccgagcttg
     3721 gcagatggtt gtacggatgc ttttcgactt tgtagggctt gttgcaagct catgccttgt
     3781 ccaaactgtg tcgctctgcc attgacataa gaagccttaa agctagtatt agctggacga
     3841 gcgaggcctt gataatcaag caagtcactg gaaatttctc gaataaagcg gcttggttgg
     3901 ttgtagttgg tgcgaccgaa aaggagtcga gaattggcat tggtcaggta gagagtctgc
     3961 tcagcacggg tgatgcctac gtatgccaaa cgacgttctt cctccaattc gtcctcttct
     4021 tctgctgcac gactaagtgg gaagacattt tcctccatac caatcaagaa gacaactgga
     4081 aattccagac ctttggctgc gtggagggtc ataagagtca cttctgaaga ttctgtatcg
     4141 ccatcatctg tgtcagcaat cagggccaaa tcaagcagga agcgtgttaa tttatctaga
     4201 cctgtctctt cttcctcaac atccttttca tcaaagtttt tggtaacaga aaggaattcc
     4261 tggatgtttt caatgcgggc atttgcttcc agggtatttt gtgctgcaag ggcatcgatg
     4321 tagcctgttt ggttcaatac tgcctcgact acttgggtaa ccgtcaagtt gtctaattga
     4381 ttgcgaagat tatagaggag attggctagg tcaaagactg cctgcgctgc cttgcccttg
     4441 actggtgaca acataatatc ctgagaagct tctagcaagg acatactgtg gctggtcgca
     4501 aaatcacgga gtttgtcaac cgtaccaggt ccaacgccac gtttgggctc attgacaatg
     4561 cgttcatagg agatattatc cgatggattt gcaatgatat tcaaataaga aatcacatcc
     4621 cggatttcct tacggctgta gaacttggtt cctccaacca tggtataagg gatattagat
     4681 ttgagcaggg cttcttcaat ggtacgtgat tgggcattgg tacggtagag aactgtaaaa
     4741 tccttataag ccttgccttc tcggtgcaac tggtcaatct gccctgcgac aaaaatcgcc
     4801 tcgtcattct catctctggc acgatagtaa gtaatcaaat ccccttgggc attctgtgtc
     4861 cagagttttt tgggacgtcg attgcggttg ttttcgatga cctcattggc agcctgcaag
     4921 acgttcttgg tcgaacgata gttttcctcc aaaagcacaa ccttgctctc tggatagtcc
     4981 ttttcaaagt ccaggatatt ttgcatatcc gcaccacgcc aaccatagat agactggtcc
     5041 gcatctccga ccacgcagat attcttgaaa cgtgatgcca ggagcttgac taattggtac
     5101 tgggcatggt tggtatcctg atactcatcg acatggatat actggaattt ctgctggtaa
     5161 taggtcagga cctctggatt ttggtcaaaa aggcggagcg tcaacataat caaatcatca
     5221 aagtcaacgg cctctgactg tcttagttcc ttttgataag ccgtgtagca tttagcaaca
     5281 atctgcgtgt ataggtcgcc tgcctgcgct tcaaatgcct tgtcatcaat caagtcgttt
     5341 ttggcattgg aaatggtgcc caggatagaa cgttcactcc actttttcgg atctagattg
     5401 agatttttta aaatccgttt catgagactg cgttgctcac ctggatcgac aatcgtaaaa
     5461 ttgcgattgt aaccgatatg gtcagcatcc cgacgcaaaa tccgcacaca catggagtgg
     5521 aaggtagcta tcaaacaggc ttgcgtggca ggattgaggg cataggcccg ctccttcatc
     5581 tcccgtgccg ccttgttggt aaaggtaatg gctaggatat tccaaggatt gaccattttt
     5641 tcatcaatca aataagcgat acggtgggtc aggactcgcg tcttacccga accagcccct
     5701 gccataatca aaagcggacc ttccgtcgtc tgtaccgctt ctgcctgtct gtcattcatt
     5761 ccgtttaata atgggttcat tttctcatac tttcttagaa catgtattac aagtggagtg
     5821 cttttaaata agagatagtt tttcgctaat caaggcagtt ttttgaagga ataccgactg
     5881 tattttttga aaaacaaacg atgaatagct gaaaaactag gcttagatgg aagtactaca
     5941 ctgtgaatac aggttcgtta taatcattct ctccattata ccaaaaaatc tctcgataga
     6001 cagttcaatg tgatagatgg caagcaaaaa aagcccagag tcatctctga gcttttgtat
     6061 tcaattaatt attcagcacc caaggcagct actgtgatgt agttgtatgg tttgttgaag
     6121 tgtggcaaga agaacaagtc tgtcaaggcc aatttttcga ttgttacacc ttcttggatt
     6181 gccaatgaga agaggtggat acccaatgag atgtcttcac gagcagccat ttgcgcacca
     6241 aggatacgac gtgaatcttt atcgtaaaca atcttgatag tgacagggaa gttgccgtgc
     6301 tccatgaatt ctggtttttg gttgtctgtt acttcagtaa cagcagcgtt caaaccaaga
     6361 cgagtagctt tttcaagtgt caaacctgtt gatacaaggt taagaccgta gatagagata
     6421 ccgttagaac cttgtacacc gataccttca aggtcagtgc cacagatgtt gtgagctgct
     6481 acgataccag tacgtactgc atttgaagcc aaagcgatgt agcttgtatc gccagtagcg
     6541 ttgtcgtaga ttgttgcaca gtcaccgata gcgtaaacgc ctgggataga agtttcttga
     6601 cgtttgttta caaggaaggc accattacgg aagcgctcga ttccttcacc tgcaagcgca
     6661 gtgtttggac ggaaaccaac agccaagata accatgtcaa catcgtattc gttcttgtca
     6721 gtgatgattt tctcaacttt accattacca gcaacttctt taacagtttc gccgaaggca
     6781 agtttgatac catgctcttc caagttttta gccataaggt ctgacaagtc acggtcatag
     6841 tacccagcca aacatgtatc cacaacatca ataagtacta cttctttacc tttacgttgg
     6901 aatgcttccg caagctcaac accgatgtaa ccagcaccaa caactgcgac gcggttgatg
     6961 tctttgtttt tcaatttttc aataacatct gctgagtttt ggtacaattt aacaaattgc
     7021 aagttttcaa gagttgcttc aaattcaagc gaaccttctt tgatttcagc tcctttgatt
     7081 ggtggtaaga taggttgtga accagttgcg aaaagaagtt tttcaaatga ttcaacatgt
     7141 tcttgaccat ttacaagcgc tgtaactgtt ttggcatcat agtcaatgtt tgtaacaggt
     7201 gactccatgt atactgtcgc acccaagctc tccaactctt ctttgtttga gtagaaaagt
     7261 ccttcaggac cgccaatttg ctcaccgatc cacaaagcca taccacaacc caagaatgaa
     7321 atatttgagt tttggtcaaa tacaacgatt tcattttctt gaccataatt tgtcaacata
     7381 gttttgattg cggcagtacc agcatggtta gcaccgacaa caacgatttt agccataatg
     7441 taaaatctca ctttcgaaaa tatatttttt tacgaactat attatacaat ataaatgtta
     7501 ccgatttcaa aaaatatgct cagaatatca catttttttc aaaaagtttt tgaaatgcta
     7561 ttttctttaa acaatgtaaa gatatataaa agcaaaaacc tagatttctc taggtttctc
     7621 ttaacgtact tgttcaaaac gcagatgtac aataatctta tcgccatagc cgttacgttc
     7681 taaatcacgt tgcaagcgat aggaaatgta atgctcagca atagaaatat accctgcatc
     7741 taaaagacga tgttcaactt gcgactgaac catgctaatc gttggtcgct ctgtatgagc
     7801 ttcttccaag tcaagcacta ctttctttgt gacctgagca agatttttcc gccaagtttc
     7861 atcaatgaca tagactgtct gtgcagcttt aatgatggct tggtagattt tatctggatc
     7921 aaattcaaca atctctccac tacgtttaat gacttgcata aaagctcctt tctggttttc
     7981 agtaaaccct ttcatactta cattatctag gtttttgtgt attttgtcaa gtattctttt
     8041 tcataaattt tgccttggct tattttcgct gaaagccctt tagtatgata taatggacct
     8101 attaaaatga aataaggaga aaatcatgac aaatgcaatg cctaaacgtc aagaaattga
     8161 tgtgcaatta acttgggata cggacattct atttccgacc cctgataact acaaagaaaa
     8221 tttggcagcc tacgctaagc aagtgacagc tttcgaatcg aattacaaag gaaagctaac
     8281 tgataaggat accatcgttt ccgccttaac agaatacgaa aaaatcgtta ttcttgatag
     8341 cagactttcc cactatgcct tccttccttt ggaagtcgat aagatgaata ctgaattggc
     8401 gagcctggcc aacgaatacg acctcgtttc tgccaaggca cgtcctcaac gagatttcct
     8461 ctattcagaa cttggtcaat tagatgaagc ctttctactt gaattaaaag aagaacaacc
     8521 acaattggct gcattctttg atgctattct ccgtgacaag ccgcatcaac tgcacccact
     8581 tcaagaagaa cttttatcaa attttgcacc aacatttggt cagccctata acaactacgg
     8641 tgtgaccaag tttgaagata tgacatttga aaacttcgag gcaaatggcg aaacgctcgg
     8701 caatagctat gtgctctttg aaaatgatta tgagctcagc catgataccg aaatccgtcg
     8761 caattcagct gctggtttct attcaacctt gaaaaaatac aagaatacaa ctgcagcaac
     8821 ttatttgtct catatcaaga atgagcaaat cgaagctcgc ttgcgtggat ttgacaatac
     8881 gattgacttc ctcttgcata gtcaaaatgt ctctcgtgat ctcttcgacc gtcagattga
     8941 tgtcatcatg aaagaattgg ctcctcacat gcgtcgctat gtaaaattgg ttgctaaggc
     9001 tcatggattg gacaagatca cacatgctga cttgaaaatc agtctaccat ctgaatacaa
     9061 ccaacgcatc acacctgaag aatccaaaca attcttgatt gactgcctgg gcattcttgg
     9121 tgaagattat gtgaaaatga ttgaacaatc atttgatgag cgttggattg actttgctca
     9181 aaacgaaggt aaggctactg gtggcttctg tgctactctt tacgatggac catcttacat
     9241 cctactttca tggacaggct tgatgaacga ggtcttggta ttggctcacg aattgggaca
     9301 tgctggtcat ttccaattgg ctaagaaaca aagtgtcctt agctacgatc catccctcta
     9361 cttcatcgag gcgccttcta ctgcaaatga agtcttgaca tgtaacaccc ttttgaaaaa
     9421 caaccaagac cctggcttcc aggcttactt gattagcgag ttgatcagcc gtacttactt
     9481 ccacaacatg gtcactcact tgcttgaagc agccttccaa cgtgaagtct acactcgttt
     9541 ggacaatgaa gaatacctca acggtgatat tctctgccaa atcaagttgg atgtcatcaa
     9601 ggaattctgg ggtgaagact ttgaaatcgg tgacgatgca ggtcttatct ggatgcgtca
     9661 accacactac tacattggtt tgtatccata tacctactca gctggtttga ccatcggtac
     9721 ggctatggcg aaacaattgg aagaacatcc tgaagaagtt gttgaaaaat ggttggaaac
     9781 cttgtcactc ggtgcaagtc tttctgccca agaccttgct aagcacgcag gtgttgacgt
     9841 ttcaactgac caaccactca aagaaaccat tgcctatgtt ggttcattgg tggataaatt
     9901 ggaaacacta atctaagaca cataaaagac ttgaacttgt tcaggtcttt ttgtctattc
     9961 tttcttgata ccaatttccc acgtaggtca attcatcctg acttaaaaaa tgtcccttgt
    10021 caaaacgaac taggttggct ctgggaaaag ctgacgcttg ccagtcatct acaagatgtt
    10081 caagagcgac ttggtcgacg agttggtcat tctgccccag tgtaaataaa atctctgctc
    10141 tgctattttc cataggaaaa gcgtaatcta aggccgaagg gtggagcaag atataattgt
    10201 ccgccaggtt tgactgcttg gccaacaagc ccatgataaa gttagcaccg tttgaaaaac
    10261 ctacgaaagt aatctgacga taatctcgga tgtccaagtc ctgccaaaaa tccagaaaag
    10321 ccgacaagcg catttcaaca tcgacaagat ccagctgacc gtcaatgaga ggtgcaaaga
    10381 aacgcctttc cctgccttga ccccaacttc catctaagga aaggacaaaa gcttctggat
    10441 ccagctgtta gcgaagaaag agcatggatt ccttgttgcc acctgtgccg tggaaaaaga
    10501 ccaaaagact gggactggtc cctttgataa agcgataatc catacttcat ttctcctaat
    10561 aacgttggga gagatttttt tcgatttcct gtctatcctc ttcaaagaaa cttggcaaaa
    10621 ataggtctac ctgatccaac tcttcattct gagctggcat ttccgattcg cgctcaccag
    10681 tcatggttgc cacctcaaac ataaggtaat ttggcgctcg gaagtacaag gaatgaatga
    10741 aatctcgatt aatgatacca gaatgtggac gattgatgag atttaagcga ctaatcaggt
    10801 cttccaagtc ggactcatct aagacaccaa atgcgatatg atgaatggcc ccgactccca
    10861 taacgctgat tggcgactct tggtcaagta tcaaataaag tcgatgttgg aaggtgttat
    10921 caaagagaag agaaatcact atcttatcct caaagacaaa tcgactttcc tcaacaaatc
    10981 cgaaggtttc tgtcagcaaa cttagtaatg ccttttcttc acgtattcgc atgtgaagac
    11041 tggcaatgcc aagaatagcg tattccgacg gaatttcatc tattttatac ggaaacattt
    11101 ctccgatagc gttatgatag gtcaagccaa gcaactggcc atcttcatct tggaaattca
    11161 gaatatgccc atttccaaaa gcctgaattc cttcattctc cacttcaaac tctgtcagtc
    11221 ttttctgcca gaattctaat gcctcaaaat tttttaccag aaaaacagtt ctttccaaac
    11281 gattggttcc gtttcgatga ttgggatggt taggcatatc aaaaatggta aattccgttc
    11341 catagcggcc ctcttcatca ccgaaaaaga gatgatacat gcttgaatct tcttgattga
    11401 cagttttcaa ggtcaatttt aagccgagaa tatgatgata aaaatgatag gcttggtgta
    11461 tgtttcctac caagcttgaa atgtgatgaa tacctgtatt gttcataaga tgacctcact
    11521 gatgttgata gacatatttt atcactaatt attgataaat aaaaatcttt tgctcacgat
    11581 tgacagccaa gtaataaaaa acttccctaa ccattgctga ttagagaagg atatttttta
    11641 aaaaatgaga ccataaagga gagccgcaag caagcctccg atgattggac caactactgg
    11701 tacccatgca tagccccaat ccgaatctcc cttgtgcttc aatggaagga tggcatgcat
    11761 gatacgagga ccaagatcac gcgcagggtt tagggcatat cctgttggac caccaagaga
    11821 aactccgagt gagacaatca aaccaccgac gattaaagtg ccaatccctg ttggaaaatc
    11881 atactgaccg aaagccagta atcccaagac caaaacaaag gttccgattg cttcgctaat
    11941 tgtattagaa acaaggttgc ggatggcagg tccagtagag aaagttgcca acacagcacc
    12001 agtgtcttct gttgcatcgt agtgatcttt gtacatgagg tagaccaaga tacttccgat
    12061 aaaggctccg ataaattgag caaggatgta agggactaca gaagcccatg ggagatttcc
    12121 tgcaaaggcc attgcaattg atacagctgg gttgaggtgg gcagttccca ataaaccact
    12181 cacaaaagct gccatggcta ctgctagacc ccaaccaatt gtgattacaa tccaaccagc
    12241 atccttggcc ttactcttat ctagtactac tcctgctacc acaccattac ctagtaagac
    12301 aagtaaggtg gttcccaaca cttcaccgat taattcattt gtcatcatgc acctctttct
    12361 atttttcttt caaataggtc aaatcattct taacaagtgt atctgccaac aattgtttct
    12421 gttgagcaac ttcttcctct gaccaagcat aataagctgc catttcctta atgatttcaa
    12481 gcgcaactgc atccaactgc tcacgcataa agagcatgta gttggtacga cgaagaagat
    12541 agtcaactgc agtcaaggtc atctcttcct tcatagcata gtgaagggaa agcaaatcac
    12601 gcttgttcaa gccagaaacg gcttctactt tatggtttaa tacaaagact tttggagcat
    12661 ttgaaccgta caagtttgcc aagtaaaggg cgtcatcata aaggagacct ttcttcacac
    12721 ctagttgagc aagatgttca atttcttctg ctacgtttgc agggttcaat tcaccaccag
    12781 agactggata ggtcttagaa ttgatgagtt tgaagctgcg accatgttct tctttgagaa
    12841 tgtctgccac tttttcaatt gcaccttccg ctatcttacg gaagtcagta atcttaccac
    12901 cagcaagagt cagcaaacca ttgtcatcac ggtcaagggc agagccacgt gatacagctg
    12961 aaggatccaa gtgtttttca gaaacgctgc cttccagatg ggtcaaatca tgttccacat
    13021 cgtcacgtgt cttttcattg ttcatataac ctttgaccgt ttcaatcaag ctattaaagc
    13081 tgtcatcgct gagcttaccg ttgtttccac cattgtagtc agaagcacca tttccagaca
    13141 agaggggacg aagacctgcc caaccactct caatgtcatc cagggtcaag tttgcttctg
    13201 ggaagcgatt gttgacaata tcaagcaggt agtcaacatc ttcttgggtt accattggat
    13261 ttgccaaatc accagtatag tctgtatcag tcgtaccaaa ataggtttta ttttcacgcg
    13321 gaaggacaaa gaccattcga ccatccgcat ggccagtatc aaagtaagtc ggctgtggta
    13381 cagacaagcg agagctatcg acaactaggt gcacaccctt ggtcggacgc atctggagaa
    13441 cgcctgaacc ttctccaccc agattacgca cttcatcact ccatggtcct gttgtattga
    13501 tgaccaaacg cgcacggatt tcaaaggtgc ggtctgtcag caaatcacga gcgacgatac
    13561 cgacaacttt tccagcatca tctttgatga atttctcagc tttggcacgg ctggcaatca
    13621 aggcaccatc cttggctgca cgtttgatat tttcaataac caaacgagca tcattgttgc
    13681 ggaaatcaag atagacaccg ccaccaatca atccttcttg cttcaagttt ggttcgcgtt
    13741 caagtacttc ttctcttgtc aagaccttat tggccatatc ggtattattg acgccagcca
    13801 agagatcata caagtccatg gccactttca aacggaagag gctgaaggta gaacctggct
    13861 catcatagac tggtaaaagc attgggtctg gctttggaat atgtggggcg atattttgta
    13921 ctacagcacg ttcagatacg gtatcggata ccacttccac gtcaaattgt ttgaggtagc
    13981 gaagaccacc gtggaccaat ttggttgagc gactggaagt tccttctgca aagtcctgca
    14041 tttcaatcaa ggctgtttcc ataccgcttg ctgctgcctg caaagccaca cctgcacctg
    14101 taataccacc cccgataatg aggaggtcaa gttgacgatc ctgcattcgc tcaatagcta
    14161 agcgtcttgt ttcttttgaa aattccatac gattcacttc ctaactttcg aataggactg
    14221 tctagcaagc agaaattctt ctttccccta gctaacaagt cctttattgc tcttcatcca
    14281 cttctgcaaa tagttgagtt gctgcgacag cttttttcca tcccttgtaa agttgttctt
    14341 tacgagcttc gttcatggtt ggttggaagg attggccgac agcgttgagt tctttcaatt
    14401 catccaaatc tttccagaaa ccaactgcta aacctgctaa gaatgctgct ccaagagctg
    14461 tagtttcaag gttttgagcg cgtgcgattt caatacccaa aatatctgct tggaattgca
    14521 tgaggaggct gttcattgct gcaccaccgt caaccttcaa gacagaaata tcaatacctg
    14581 tatccaattg catggtgtca ataacatctc gaacttggta ggcaatggat tgaagagttg
    14641 ctttgacgaa gtcttcttta gtcgtaccac gagtgagacc aaagactgag ccacgcgcat
    14701 ctgagttcca atacggagca ccaagtcctg taaaggctgg aacaacatag acttcatcat
    14761 tgctggtaga cttacgagca agctcttctg actcaggtga tgtagtcacc attcgcatgc
    14821 tgtcacggag ccattgaacc gccgaaccag cgataaagat agatccttca agcgcataat
    14881 agactttgcc accgatacca tagccaattg ttgtgagaag gttgttctgt gacaactgca
    14941 tctcttcacc tgtattcatc acgatgaagg aaccggttcc gtaagtattt ttcaccatac
    15001 ctggctcaaa tgctaattgt ccaaataagg cagcctgttg gtcacctgcc atgccagaga
    15061 ttggcacttc tgcgccatag aaatggaatg gagctgttgt gccgtaaact tcagagtttg
    15121 aacgaacttc tggcagcatg gcttttggaa tattgagaag agataaaatt tcatcatccc
    15181 atttcaactc ttcaatgttg tagagcatgg tacgagctgc gtttgaataa tccgtcacat
    15241 ggcatttccc atcagtcaat ttccaaacca accaagtatc aatggttcca aagagaatct
    15301 cacctttttc agcacgttcc tgcgctccag ggacttgatc taaaatccaa cgaactttgg
    15361 ttgctgagaa gtaggcgtcg actactagac ctgtcttttg atgaatcata tctgcatgac
    15421 catccgcctt cagctggtca gcaatatgag ctgtttgacg agattgccag acaacggcat
    15481 tgtagattgg aagacctgtt tccttatccc agacaacggt tgtttcacgc tggttggtaa
    15541 taccaattcc ttcaatctga tcaggacgaa caccgctttc gataaaggac cctgcaatca
    15601 cagactgaac agaattccaa atttcattgg cgttgtgttc aacccaacct ggtttaggga
    15661 aaatttgcgt aaactctttt tggtaactgc caaccttttc acctttttta ttgaagataa
    15721 tggcacgtga acttgtagtt ccttggtcaa tggccatgat atatttttca gtagacatag
    15781 gtctccctcc tgtttgttta tctttttttg aaaacgcttc cattttcttg gtaattctat
    15841 tctaacccat tcttgtgaat ttttcctatc atttttttca aaaaaataaa aaaatctgat
    15901 aagcagtggc tagaaagatg attctatcaa ctgttatcag agtttataaa ataaattttt
    15961 caaggttaaa tgcacttaca tttttcacaa agactatctg acatcatcta gcgatgctcg
    16021 ataggaaaag aagttttggt cgccataatc tctgattgac aggacttttg atgatatata
    16081 tcctgtatcc atgcctttaa ttgtacgata tcttggattt tcaatcgatt tcctaggcaa
    16141 taaactggaa tgcttgtatt ttcgaggtaa tctgtaataa tcaaatcata gtcatatcct
    16201 gcttgatagg gctcaataag aacctgacga ttgccttcta acttctccct tagttgcaac
    16261 aagagaggat aggatagaac ctcatgtagg gaagaagcaa aagcaacctt gacctgtata
    16321 ggctggacct gaccaaaata aatatacaaa tccgcaatat ttgtcagata agagttcctt
    16381 atttttttat cgacttttct atgaaaaact gatttataga cgtcttttag caagtcttct
    16441 gcttctgaat agaaactaga agcttctacc tcttccagtt caacggaaga ataaaagaaa
    16501 tatagctggc tcatgatttg gttcaaatga tagagcgctt cttctgagac tggtaaattt
    16561 ccctcaaaat ataaccgtaa tttctgaaga gccaaagagg tagcttccat aatcggtcca
    16621 ccgaaaccaa gaacctgctc taattgatgc ggcactaaaa taaaatggct aaacaggaaa
    16681 gcaaacaacg ccataatttc cccttcttgg aaagaggtgg attgttgctg acttagtgta
    16741 aaatacatct ttctcaaacg tcggtaaaac ttatgttctt gatagggttc catcaatttg
    16801 taaaggtgct taaaatctag ctgtcgcaat cgagagcgtt gctgtgaaat cattaaccac
    16861 aacaacagac gatgggcttg cttgggattt agcggcgatt gatagaagcg ttcgaaaacc
    16921 ggcaataagg cctctatttt ccctagcata aactcttctt gtaattccgc tctcgtagta
    16981 gtcaaactca acatttgatg taaaaagtac cgtatttgaa gctcactacc ttttagacga
    17041 ccacttttga ttccaatacc aaattctgcc aatatctggt tcaaagaggc aagatggcga
    17101 ttcagagtcg cttcgcttat cagcaattct tgagccagct gttgaataga aacctcttcc
    17161 ttatcagata aataaacaat aatttgatat ttggtactgg tttgacagag atagtctagg
    17221 atacgatgaa gactcaaact ggcctttttc ttcaaaaaga ccttttcatc ttcgagttga
    17281 aaagagagtc ccaagtcggt tacttctgct tcttcattga aagatacaat atagcgaaaa
    17341 agagttaatt ttgacaattc taaatagtga caaatatcct ttagcgatgg cgcctctttc
    17401 ctatcttcta agtagaggag aagctgataa atggcgagct cacgcttttc caataaggaa
    17461 tcaatccgca tagacaccct ccccatcaac ctgataaaat tgccgaatat actcttgagc
    17521 ggcctctacg atgaagggga ccagaggagt atttccagga agacagagcc aagaatgttc
    17581 taccaagtca aagacggtca aatcctttga aatcgctaga gacagtacat ccatctgttc
    17641 aatataatct gcagtagaaa cgagttgccc ccctatgatg cgcccactcg tttcttcgac
    17701 aatcagcttg aaatctacta aagttggttc ccactggcta tacgaccttc taatccgaat
    17761 cgatttactc tccaaccaca agctcgcctc actctcggtc aagccaaggc tagttatata
    17821 atagccaaat acatgactag aaacaatccg ctgggctctc ttaataggag caatcctctt
    17881 ttgcaaattt cgagcagcca tcctccctgt cataatcgca tgatgaatca tcggaagata
    17941 tgcctgtcca aaataatcta ctgggagact gaccaaatca cctacagcaa aaatattctc
    18001 ttgacttgtt tcaagaaact catccaccca tacagtccct tctgcaatca cttttagcct
    18061 gtctttcact agctgaatat tgggcgtcaa attggtggat ggcaagacta aatcagctgg
    18121 ataattacct gtgactgtat gacaaaccag ctgttcttcc tgagtatcaa tcgttatctg
    18181 attgactgtt tcggataaat gaagttggat tcctcttttt ttcatctctt gacgaatcgg
    18241 cgcaatcata tcctcatcaa cgtactttgc aaggagtgaa tcttgcgcct caaacacatg
    18301 caaattcaaa tccaactggc taagggcatc caagctttcc aaaccaatct gtcctgctcc
    18361 aatcactgca actgtttttg catttgtcaa tttctctaga ctagcttgtg cttgagatag
    18421 cgtttttgag cgaattagat agtcttgaag ttcttccgtt ccccattccc atgtttgact
    18481 agctcccata gccaatatta gccggtcata aataatatca cctatatctt gatgatgccg
    18541 tatctttacc tttcgcattt cgggataaac tgcgagacat tctgtttcaa aaagacaaga
    18601 aatagctgca tgctgcacct cgctgaacaa agaaatcttc gcttcttccc aaccagaaat
    18661 ttttcctgcc actttccaat tcaaggtatt tggaaagtaa gccacatctt tttctctatc
    18721 aattagtgtt atttgagcat tctgatacaa ttttcgacat tctaaagctg cacttaaacc
    18781 agcaaaggag gcgcctataa taacaatatt catacttaat ccttttatcg tttttagtca
    18841 ttatatcaag aatgaccaaa aaattgaaaa ggcttgcaac tgaaaagcac accagataac
    18901 tgatgtgctt gtgtaaactt aaataaaacg aggaagatgg ccagaagctc ctctagatta
    18961 atatttttct aaacacctca ctctttatgc cctaactcac gttaaaatag tcactcccct
    19021 gactatttta ataatccggt cttacgactc ctgtcacagt ggctttggtc gcttcgtagt
    19081 cgccgtccac tacgactttg ataatgcgtt tagcatcttc ttctgggcat ggaaccaacg
    19141 gcaagcggag tggaccaact tcaaatccaa ggtaattaag aaccgcctta actggtgcag
    19201 gacttggata tgagaagagg gcattgactt tcggaatgaa cttgcgttga atagcggctg
    19261 ctgttcgaat atcttgttgt tcgatggctg taaacatttc atacatctca tcaccattcg
    19321 tgtgagatgc aacagaaatc acaccatctg ctcccaagtt cattgcatgg aaagcatcgc
    19381 catcctcacc tgtataaatc aagaagtctt ctggtttatg ctcaattagg taagccatgt
    19441 tagcaaggct ggtacactct ttaacaccga tgatgtttgg atgctcagcc aaacgcaaca
    19501 tggtttctgg cgtcatttca accacgacac gacctgggat attgtagata atgattggca
    19561 aatcagaggc atccgcaata gccttgaagt gctgatacat tccctcttga gagggtttgt
    19621 tgtagtaagg cacgatagca agacctgccg caaagccgcc gaatgccgcc acttctttgg
    19681 caaactcaat cgagtcgcgc gtatcatttg taccgatacc tgcaattagg ggaacacgac
    19741 cattgacaat tttttgcaca gcaccaaata gttccagttc ttcctcgtgt gtcagggttg
    19801 gactttcggc agttgttcct gctaataaaa tcccttctgt gtgatgggac aacagatgtt
    19861 caatcaattc gggtaaaact tcaaaattaa tcgaaccatc ttctttgaaa ggggtaatca
    19921 ttgctgtaat aatttttaca tcacgtaaat cttgaataga cataggcttc ctctcttact
    19981 gattgttgct aaaaaaggct gagtgcagcc ttttgtgtac ttttggttaa taaaattatt
    20041 tcaattcaaa cttcaattct gccgttggac gaactagacc acgctcatga agggtttcag
    20101 cgatttgaac agagttccat gcagcgcctt tgagcaagtt gtcagaaaca acccacatgt
    20161 gaataccgtt ttccttgtcc aaatctttac ggatgcgacc aacaaaagta tcgcgactac
    20221 caacagcatt aatggcttgc ggataaattt gattagccac atcgtcttct aaaacagccc
    20281 ctgggaagga tgcaatagct gccttcactt catcaatcgg tgcaatttcc ttagtttcaa
    20341 tgtaaacaga ttcagagtga gctgacaaga ctggaatacg gacgcaggtt gcagaaacgg
    20401 caatgctgtc atcttccatg attttcttag tctcttttgt catcttcatc tcttcgtatg
    20461 tgtagtcatt ttcagtgaag aggtcgattt gcggaatagc attgaacccg attggatagt
    20521 gcttcttatc gccaccagaa ggaagaatat tcgcttctac cgctttgggt tccacgccat
    20581 cattcaagac agaacgaagc tgagcttgtg tttccaagat agctcccata cctgctccag
    20641 agactgcctg ataggtggat acgatgatcc gctccaagcc ccatttctga cgaacaggct
    20701 ccaaggcaac catcatttga atggttgagc agtttggaca agcaatgata ccattgtggg
    20761 catcaagcgc gtgagcattt acctcaggaa caaccagagg aacatctgga ttttgacgga
    20821 agtaagaggt attgtcaact actacagctc ctgcttttac agcgtaagga gcgtacttgg
    20881 cagatgtaga gccaccagct gagaagaggg caatatccac tccttcaaag gctgtttctg
    20941 ttgtttcttc aatgacaata tcctgcccct taaactgcaa ggtcttacct gctgaacggg
    21001 cagaagcaag gaaacg
//
LOCUS       DBNFCO010000034        20827 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.034, whole genome shotgun sequence.
ACCESSION   DBNFCO010000034 DBNFCO010000000
VERSION     DBNFCO010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 20827)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20827)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20827
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.034"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(<1..660)
                     /locus_tag="AC1PIV_001038"
     CDS             complement(<1..660)
                     /locus_tag="AC1PIV_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIRAN domain-containing protein"
                     /protein_id="HIP6612070.1"
                     /translation="MGQGTTISLIKEEIIQQEKQIEGIFLEIENLRIMKKQCKNWLFF
                     AITMLFFSVIVFKGMFLVIMVFLCFMYVVTSYFQSDRCDGLISHYKNEIDSIEEAINK
                     NREFIAKYKYFSHFYVAGTQYREDRFEPMRVLRCLTYGGETTDVKLVREPDNKYDPNA
                     VKVLVCGYFVGYIPKTASEEVSRLIDRGEKLNLSVDMERQGSYDKGYRAYYELTIYVL
                     ND"
     gene            complement(764..1177)
                     /gene="ndk"
                     /locus_tag="AC1PIV_001039"
     CDS             complement(764..1177)
                     /gene="ndk"
                     /locus_tag="AC1PIV_001039"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002934976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004550 - nucleoside diphosphate kinase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HIP6612071.1"
                     /translation="MERTFFIIKPDALKRGLAGQILSRIERRGFQIRDLKMVTATEEL
                     ISQHYEQLTDKPFFPQLVQYMTSGPMIAGIIEGPEIIKSWRDMMGATNPVNALPGTIR
                     GDFATAPVEGIVANVVHGSDSAEAAEREIGLWLGK"
     gene            complement(1200..1787)
                     /gene="yihA"
                     /locus_tag="AC1PIV_001040"
     CDS             complement(1200..1787)
                     /gene="yihA"
                     /locus_tag="AC1PIV_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HIP6612072.1"
                     /translation="MEINTHNAEILLSAVSKAQYPGYDIPEIALAGRSNVGKSSFINT
                     LLGRKNLARTSGKPGKTQQLNFYNIDDKIRFVDVPGYGYAKVSKTERAKWGKMIEEYL
                     TTRENLRVVVSLVDMRHEPSADDVQMYDFLKYYEIPVIIVATKADKIPRGKWNKHESM
                     IKKKLDFDKNDQFVIFSSETRHGYDQAWDAILSNI"
     gene            complement(1843..3069)
                     /gene="clpX"
                     /locus_tag="AC1PIV_001041"
     CDS             complement(1843..3069)
                     /gene="clpX"
                     /locus_tag="AC1PIV_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002943186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HIP6612073.1"
                     /translation="MAVKHTHELIYCSFCGKNQEEVKKIIAGNNVFICNECVELAQEI
                     IREELAEEVLTDLADTPKPQELLNILNNYVIGQDRAKRALAVAVYNHYKRINFQDSRD
                     ENDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENIL
                     LKLLQAADFNIDRAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVA
                     SVPPQGGRKHPNQEMIHVDTKNILFIVGGAFDGIEEIVKQRLGEKIIGFGHNNRAIDE
                     KESYMQHIIADDIQKFGIIPELIGRLPVFAALDQLTTEDLVRILTEPKNALVKQYQTL
                     LSYDDVELDFDEDALLAIAEKAIERKTGARGLRSIIEETMLDVMFEVPGQDNVKRVRV
                     TKAAVDGKEKPLLETA"
     gene            complement(3091..3264)
                     /locus_tag="AC1PIV_001042"
     CDS             complement(3091..3264)
                     /locus_tag="AC1PIV_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612074.1"
                     /translation="MERSLFGLFTAFLCGICVLCAIQAFRKKRFGLAILFLLNAFTNL
                     VNSIHAIYGFLFR"
     gene            complement(3267..3779)
                     /locus_tag="AC1PIV_001043"
     CDS             complement(3267..3779)
                     /locus_tag="AC1PIV_001043"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0046654 - tetrahydrofolate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HIP6612075.1"
                     /translation="MTKKIVAIWAQDENGLIGKGDRLPWSLPADLAHFKKTTTGHTMV
                     MGRITFDGMGKRALPNRHTIVLTTDKTYQLESERITILHSVEDVLDWYNKQEQTLFVI
                     GGGQIFTAFAPYIETLIVTDIHGQFNGDVYFPKAFPMEKFQLQSANLRPKDEKNPYDF
                     TIKTYERRDG"
     gene            complement(4065..4904)
                     /locus_tag="AC1PIV_001044"
     CDS             complement(4065..4904)
                     /locus_tag="AC1PIV_001044"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HIP6612076.1"
                     /translation="MTKADIIFKENIRKIMEEGVFSENARPRYKDGNVANSKYVTGAF
                     AEYDLSKGEFPITTLRPIPIKSAIKEILWIYQDQTNDLSVLQEKYGVQYWNDWEVEGT
                     GTIGERYGAIVKKHDIISKILKQLEENPWNRRNVISLWDYEAFDQSAGLLPCAFQTLF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAEELLRRTPSEVEPRLVLNVPDGTNFFDIRAEDFELVDYNPVKPQLKFD
                     LAI"
     gene            complement(4957..5259)
                     /locus_tag="AC1PIV_001045"
     CDS             complement(4957..5259)
                     /locus_tag="AC1PIV_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612077.1"
                     /translation="MNLTLLKRLNLVLYGIAIFLFVMLFLPIGQWFDIVNVNFKLTFF
                     IIPFFGLASLPTAIYTKNVRQILLSVLLVALYFILFSLITALSGLFHLNFYSFFFK"
     gene            complement(5271..5549)
                     /locus_tag="AC1PIV_001046"
     CDS             complement(5271..5549)
                     /locus_tag="AC1PIV_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612078.1"
                     /translation="MKQVNMSKIINYLTILGLLILLSAFFLDNWIRDWFFPSSWGNVA
                     TMLILPLLGALILILSIYYKKLWTGLISIFLIISFPLIFGIGYFIFGP"
     gene            complement(5675..6634)
                     /locus_tag="AC1PIV_001047"
     CDS             complement(5675..6634)
                     /locus_tag="AC1PIV_001047"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004340 - glucokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0051156 - glucose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HIP6612079.1"
                     /translation="MSKKIIGIDLGGTSVKLAILTTEGEIQEKWSIKTNILDDGSHIV
                     PDIIDSIKQRFETHGLTKDDFLGIGMGSPGVVDSEAGTVIGAYNLNWKTLQLVKEQFE
                     SALGLPFFIDNDANVAALGEQWVGAGNNNPNVVFMTLGTGVGGGVIAAGNLIRGVKGA
                     GGELGHITVDFDEPFACTCGKKGCLETVASATGIVNLSRRYADQYAGDAKLKQMIDDG
                     QDVTAKDVFDLAKEGDDLALIVYRHFSEYLGVACANIAAVLNPAYIVLGGGVSAAGEF
                     LLDGVRKVFAENSFPQIKESTQIVLATRGNDAGVLGAASLVLK"
     gene            complement(6730..7065)
                     /locus_tag="AC1PIV_001048"
     CDS             complement(6730..7065)
                     /locus_tag="AC1PIV_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002934966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612080.1"
                     /translation="MKVLVMSYMVIYLLVTLGAALFSYLKTKKMNTLRLILTILSMIL
                     LTSTLYFYSQSYHDLQMVGFALGFTFISTLFLYNGTKEGSNFTTVMLFSIGRFILHIQ
                     FLILLYLFR"
     gene            complement(7066..8934)
                     /locus_tag="AC1PIV_001049"
     CDS             complement(7066..8934)
                     /locus_tag="AC1PIV_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HIP6612081.1"
                     /translation="MSDFIVEHLTKSVGDKTVFADLSFIIHQGDRIGIIGVNGTGKTT
                     LLDVLSSRIGFDGDVSPFRTKNAYKIAYLTQEPDFDESKTVLDTVLSSDLRETQLIRE
                     YELLLSHYDETSQARLEKVMAEMDSLNAWEIESQVKTVLSKLGLTDLNKTVAELSGGL
                     RRRVQLAQVLLGNADLLLLDEPTNHLDIDTIEWLTTFLKNTKKSVLFITHDRYFLDNV
                     ATRIFELDRASLTEYQGNYQDYVRLKAEQDERDAALRHKKERLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKGDLANKIDDSELEINFETSRIGKKVINFENVSFSYPDKPILKD
                     FNLLIQNKDRIGIVGDNGKGKSTLLNLIAGDLQADSGKVDIGETIRIGYFSQTIKGLD
                     ESKRVINFLQEVAEEAKTTSGMVSIAELLEQFLFPRNTHGTLIEKLSGGEKKRLYLLK
                     ILLQRPNVLLLDEPTNDLDIATLTVLEHFLQGFTGPVITVSHDRYFLDKVANKILAFE
                     DSGIETFFGNYTDYLDEKAFLASSSAISLEKPKEKTEKIKENKKRMSYFEKQEWATIE
                     EDIAGLEERIAAIEAEMLTCGSDFTKLSDLQKELDEKNDLLLEKYERYEYLSKLEG"
     gene            complement(8927..10138)
                     /locus_tag="AC1PIV_001050"
     CDS             complement(8927..10138)
                     /locus_tag="AC1PIV_001050"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HIP6612082.1"
                     /translation="MKLNNLPSEFQEALPILEKIKAAGFEAYFVGGSVRDAILGRPIH
                     DVDIATSSYPQETKQIFSRTIDVGIEHGTVLVLEGKKEYEITTFRTEEEYVDFRRPSQ
                     VSFVRSLEEDLKRRDFTVNAFALDEEAQIVDLFDGMTDLENRTLRAVGIPAERFNEDA
                     LRIMRGFRFAATLDFEIEPTTFEAMVQTAPLLEKISVERSFIEFDKLLMADFWRKGLR
                     AMIDSKAYNFLPDLAGKSDELEAMLTSLTEEFRFSTSEQAWALLFVCLGIDNIKSFLK
                     KWKTSNDFQRSVVKLVEIYQLRQAGPVTKQICFKYGKEFLYLVEELHQAQGFVTDFAA
                     IDKIDQALTIHDKHEIVVNGGHLMKAFDLKPGPVLGELLKEVEFQIVEGQLENEEQAI
                     MTFVKGILENE"
     gene            complement(10135..10902)
                     /gene="dapB"
                     /locus_tag="AC1PIV_001051"
     CDS             complement(10135..10902)
                     /gene="dapB"
                     /locus_tag="AC1PIV_001051"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HIP6612083.1"
                     /translation="MTIKVIIAGFKGKMGSTAVEMVKGDAALSLAALVDPFATETEVD
                     GVPVFKTKEEVASLEADVWVDFTTPKFTYENTRFALENGFAPVVGTTGFTPEEIEELT
                     ALSAEKGLGGLIAPNFAIGAILLMQFAAQAAKYFPNLEIIELHHDKKKDAPSGTAVKT
                     AELISQVRQSQTQGAADEEELIAGARGAAFDGFRIHSVRLPGLVAHQEVIFGAQGEGL
                     TIRHDSYDRISFMGGVNLGIKEVVKRSQLVYGLEHLL"
     gene            complement(10911..11762)
                     /locus_tag="AC1PIV_001052"
     CDS             complement(10911..11762)
                     /locus_tag="AC1PIV_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002943144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HIP6612084.1"
                     /translation="MKLAVITDSSAVLNVQSIERDDLFVLSIPVSIDGENYIEGQNLT
                     VEEFYQKMASSKELPKTSQPSLMELEEILAKLTEKGYTHALGLFLSSGISGFYQNIQY
                     LADEFEGLTVAFPDTKITSAPLGMMVENVLKWADAGLSFEEITGKLDQEIGKTTAFIM
                     VDDLNHLVKGGRLSNGAALLGNLLSIKPILYFTGEGKIEVYEKVRTEKKAIKRLLEIL
                     QEQTTEGQYQIAIIHANAPQKAENFKRQLEEAGVGSDLPIVSFGSVIGTHLGEGAVAF
                     GISPIIE"
     gene            complement(11764..12138)
                     /locus_tag="AC1PIV_001053"
     CDS             complement(11764..12138)
                     /locus_tag="AC1PIV_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HIP6612085.1"
                     /translation="MEIIRDKEFVNQYHFDARNHAWEKENGIPETKLKVDFQLIEQNR
                     AENRTSMITILRFMIVLDHFVISGAMSQAVHLPNRLVEEPTEFTDEEKRVLVEPLLDI
                     LKRMTYEVTEIAFDAPGVNLEF"
     gene            complement(12234..14189)
                     /locus_tag="AC1PIV_001054"
     CDS             complement(12234..14189)
                     /locus_tag="AC1PIV_001054"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005351 - carbohydrate:proton symporter
                     activity [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_function: GO:0090563 - protein-phosphocysteine-sugar
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIABC"
                     /protein_id="HIP6612086.1"
                     /translation="MKIQDVLRKDVMLLDLQATSKEAVIDEMIASLVDKGYVTDFDVF
                     KTGIMNREAQTTTGLGDGIAMPHAKNAAVKEATVLFAKSNKGVDYASLDGQPTDLFFM
                     IAAPEGANDTHLAALAELSKYLMKPGFADKLRGVSSPEEVISVFDAAEAADKTAEEVV
                     AAPSGDRPFIVAVTACTTGIAHTYMAEEALKKQAAEMGVDIKVETNGASGVGNKLTAE
                     DIKNAAGVIIAADKAVDMPRFNGKPLVSRPVAAGIKQPEELINLILDGKASAYTASEG
                     AATVESSEKLSLGKAFYKHLMSGVSQMLPFVIGGGILIALAFLFDGALGVPQDSLGSL
                     GSYHEIAAMFMKIGGAAFGFMLPLLAGYIAYSIAEKPGLVAGFVAGAIASSGLAFGKI
                     PYAAGGEETLALAGVSSGFLGALVGGFLAGGVVLVLRNALRNLPKSLQGLNAILLLPL
                     LGTAITGFLMFFVNIPMAAINTGMNNFLAGLEGSSAILLGLVLGGMMAVDMGGPVNKA
                     AYVFGTGTLAATVADGGSVAMAAVMAGGMVPPLAVFVATLLFKDKFTQEERNSGLTNI
                     VMGLSFITEGAIPFGAADPARAIPSFIAGSALAGALVGLSGIQLMAPHGGIFVIALTS
                     NPLLYIAYVLIGAVVSGVLYGALRKAK"
     gene            complement(14186..15097)
                     /gene="pfkB"
                     /locus_tag="AC1PIV_001055"
     CDS             complement(14186..15097)
                     /gene="pfkB"
                     /locus_tag="AC1PIV_001055"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HIP6612087.1"
                     /translation="MIYTVTLNPAIDYIVRLEDVETGSVNRMESDDKYAGGKGINVSR
                     VLKRLGYPNTATGFLGGFTGQFIKDGLIAEGIDTDFVQVDQDTRINVKIKADQETEIN
                     GLGPIVTDTQLAELEMVLAGLTKEDTVVFAGSAPASLGNEVYNRLIPVAKKAGAQVVC
                     DFEGQTLLDSLAHQPLLVKPNNHELEAIFNVELNGIADIETYAKKILEMGAQNVIISM
                     AGDGALLVTPPATYFAKPIKGTVKNSVGAGDSMVAGFTGEYVRSQDPIEALKWGVACG
                     TATAFSDDLASIEFIKETYEKVEVETL"
     gene            complement(15094..15843)
                     /locus_tag="AC1PIV_001056"
     CDS             complement(15094..15843)
                     /locus_tag="AC1PIV_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009909780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HIP6612088.1"
                     /translation="MNILKSERKQIILERIHSQQFVRLEELIEVLDTSESTVRRDLDE
                     LENEGKLRRVHGGAEAPGNLQLEESILEKSVKNVQEKREIAESAARQIVNGDVIFLDA
                     GTTTGVLIDYLQQENLTVVTNSIHHAVRLVERKIKTIIIGGFVKQSTDASVGAVALEQ
                     IRQLNFDKAFLGMNGIDKNYFTTPDIEEATIKCTIIDNAKESYVLADASKIGQFSFVK
                     VAAIEKSNIICQSSESSLLDIIKEKTRVIEV"
     gene            complement(15945..17000)
                     /locus_tag="AC1PIV_001057"
     CDS             complement(15945..17000)
                     /locus_tag="AC1PIV_001057"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HIP6612089.1"
                     /translation="MKRKVFEHYQPYKIKQKARFDLGNNENRIIDWAFLPQETLENLD
                     VNQLSFYGDNTYSELIEKYATYLGVNPKQVTVGVGSDHLIHMIVSTFMEKDDTFLTVN
                     PDFFMYETYNHMHGSRFEAIDLEEKNDTLVLPVEKLLARAEEVKAKIIMLSNPNNPSS
                     VAYSLEDLEKLAISFKGLLVVDEAYIEFANVESFISRLQQFDNVLVLRTLSKAFGLAG
                     LRVGFAVGSEELIYELDKVIPPFSLSNLTAKMAAVALNYTDKVLETVEVIQNLREEMI
                     LFLQGLDNCQVLPSQASFVTFKATWAEEFYQQALAQDWNFKYYPTGKLEGHIRLSIGR
                     PEEMDMMKKMIEKLVEA"
     gene            complement(17031..17756)
                     /gene="trmD"
                     /locus_tag="AC1PIV_001058"
     CDS             complement(17031..17756)
                     /gene="trmD"
                     /locus_tag="AC1PIV_001058"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002941457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HIP6612090.1"
                     /translation="MRIDILTLFPEMFAPLEHSIVGKARDKGLLEINYHNFRENAEKA
                     RHVDDEPYGGGQGMLLLAQPIFDTMDSIEQTKPRVILLDPAGRTFNQAYAEELAQEEQ
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKEVSH
                     TDDSFSSGLLEYPQYTRPYEYRGMVVPDVLMSGHHENIRKWRLEESLRKTYQRRPDLL
                     ENYNFTAEELTIFEKIKAEDTVD"
     gene            complement(17746..18264)
                     /gene="rimM"
                     /locus_tag="AC1PIV_001059"
     CDS             complement(17746..18264)
                     /gene="rimM"
                     /locus_tag="AC1PIV_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HIP6612091.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAKLALFDDK
                     DQFAMEVEIASHRKAKNFDIIKFKGMYHINDIEKYKGFSLKIAEENLTDLEDGEFYYH
                     EIIGLDVYENDILIGQIKEILQPGANDVWVVKRKGKKDLLLPYIPPVVLNIDIPNNRV
                     DVELLEGLDDEN"
     gene            complement(18362..19710)
                     /locus_tag="AC1PIV_001060"
                     /pseudo
     CDS             complement(18362..19710)
                     /locus_tag="AC1PIV_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730355.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
     gene            complement(19780..20763)
                     /gene="guaC"
                     /locus_tag="AC1PIV_001061"
     CDS             complement(19780..20763)
                     /gene="guaC"
                     /locus_tag="AC1PIV_001061"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007891361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902560 - GMP reductase complex [Evidence
                     IEA];
                     GO_function: GO:0003920 - GMP reductase activity [Evidence
                     IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HIP6612092.1"
                     /translation="MFNETPVFDYEDIQLIPNKCIINSRSEADTTVTLGKYSFKLPVV
                     PANMQTIIDEDVAEMLAKDGYFYIMHRFDEAGRIPFIKRMHEQGLIASISVGVKEYEY
                     EFVTSLKADAPEFITIDIAHGHAESVIKMIQHIKKELPETFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMVMIGSLFAGHIESPGKTIEVDGEKFKEYYGSASEYQKGAYKNVEGKKIL
                     LPAKGHLKDTLVEMEQDLQSSISYAGGRDITSLKHVDYVIVKNSIWNGDSI"
BASE COUNT         6102 a         4739 c         3874 g         6112 t
ORIGIN      
        1 atcatttaaa acgtaaattg tcagttcgta ataagcacga taacctttat cataactccc
       61 ttgtctttcc atatctactg acaagttcaa cttttcccct ctatcgatta gtcgggaaac
      121 ttcctcagaa gcagttttag ggatatagcc aacaaaataa ccacatacaa gtactttaac
      181 tgcatttggg tcatacttat tatctggctc acgaactaac ttgacatctg tagtttctcc
      241 gccgtacgtc agacatctta acaccctcat tggctcaaaa cgatcttccc tatattgcgt
      301 acctgctaca taaaaatgcg aaaaatattt gtacttagca atgaattctc tatttttatt
      361 gatagcctcc tctatagaat caatctcatt tttataatgg ctaattaatc catcacatct
      421 atccgattgg aaatatgatg ttactacata catgaaacaa agaaatacca taataacaag
      481 aaacatccct ttgaatacaa tgacagagaa gaacagcatc gttatagcaa aaaacaacca
      541 atttttacac tgcttcttca taatccgcaa gttctcaatc tccaaaaata taccttcaat
      601 ttgcttttcc tgttgaataa tttcttcttt gataagacta atcgttgttc cttgccccat
      661 ggtgaataac ctctctatta ttgctttttt tcattatacc actaatcagt tttttcacca
      721 atttatcaaa gaaaaacacc tagaaaacta ggtgtctgct ctgctatttt cccagccaaa
      781 gaccgatctc gcgttcggct gcttctgcac tatctgagcc atgaacgaca tttgccacaa
      841 ttccctcaac gggcgctgtc gcaaaatctc cacgaatagt cccaggtagg gcgtttactg
      901 gattggtagc tcccatcata tctcgccaag atttgataat ttctggccct tctataatgc
      961 cagctatcat cggcccgctc gtcatatatt gtactaattg cgggaagaaa ggtttatctg
     1021 tcaactgttc ataatgttga ctgattagct cttctgtcgc tgtaaccatt tttaaatctc
     1081 ggatttgaaa tcccctgcgt tcgatacgtg aaagaatttg tcctgcaagt ccacgcttaa
     1141 gagcatctgg tttgatgatg aagaaagtac gttccatgat ttttctcctg aactgtttat
     1201 tagatgttac ttaagatagc atcccatgcc tgatcgtatc cgtgacgagt ctcagaagaa
     1261 aagataacga attgatcatt tttatcaaaa tccaatttct ttttaatcat cgattcgtgc
     1321 ttattccact ttcctcgtgg gattttatca gccttcgttg ccacaataat aacaggaatt
     1381 tcataatatt tcaagaaatc atacatttga acatcatctg ctgatggctc atgacgcatg
     1441 tctactaaac tcaccacaac acgtagattt tctcgtgtcg tcaaatactc ttcaatcatt
     1501 ttgccccact tagcgcgctc cgttttggat actttagcat agccataacc tggaacatct
     1561 acaaatcgaa ttttatcatc tatattataa aaattgagtt gttgagtctt tcctggtttt
     1621 cctgacgtac gtgcaagatt ttttcttcct agaagagtat tgataaatga ggactttcca
     1681 acgttagatc gcccggcaag ggcaatttct ggaatgtcat agcccggata ctgggctttt
     1741 gaaacagcac tgagcaaaat ctcagcatta tgtgtgttga tttccatttt atacctttca
     1801 taaataaggg tagaaaacaa tcagtttcca ccctttattt ttttatgcag tttctagtaa
     1861 aggcttttct ttaccgtcta ctgctgcttt tgttacacga acgcgtttaa cgttatcttg
     1921 acctggcacc tcaaacatga catccaacat cgtttcttca atgatagagc gaagtccacg
     1981 agcaccagtt ttacgttcaa ttgctttttc tgcaattgct aacaaggcgt cctcatcaaa
     2041 gtcaagctcc acgtcatcat aagacaagag tgtctggtat tgttttacaa gagcattctt
     2101 cggttccgtc aaaatgcgta ccaaatcctc tgttgtcaat tggtccaaag ctgcgaatac
     2161 aggcaagcga ccaatcaact ctggaatgat accgaatttt tgaatatcgt ctgcaatgat
     2221 atgttgcatg tatgattctt tttcatcaat agcacgatta ttatgaccaa aaccgatgat
     2281 tttttcaccg agacgctgtt tgacgatttc ttcgatacca tcaaatgcac cgccaacgat
     2341 aaacaggata tttttggtgt ccacgtgaat catttcttgg tttggatgtt tacgtccgcc
     2401 ttgtggtggt acgctggcca cagttccctc gataattttt aggagagctt gctggacacc
     2461 ttcaccagat acatcgcggg taatggacac attttcacct tttttggcaa tcttatcaat
     2521 ttcatctaca tagataattc ctctttctgc acggtcgatg ttaaagtctg cagcctgcaa
     2581 aagtttgagg aggatatttt ctacgtcttc accaacataa cctgcctcag taagagcggt
     2641 cgcatcagca atagcaaacg ggacattcaa acttttagcc aaggtctgag ctaggaaggt
     2701 ttttcctgaa ccagtcgggc caatcatgag gatatttgat ttttgcaaat caacatcgtt
     2761 ctcatcacgg ctatcttgga aattgatacg tttgtagtgg ttgtaaacgg ctactgctaa
     2821 agcacgtttt gcacgatcct gtccgatgac gtagttgttc aggatattga gtaattcttg
     2881 tggctttggc gtatcggcca agtctgtcaa aacttcttct gccagttcct cacgaatgat
     2941 ttcctgtgct agttccacgc actcattaca aatgaagaca ttgttccctg cgataatttt
     3001 tttaacttct tcttgatttt ttccgcaaaa tgagcaatag attagctcat gtgtatgctt
     3061 aacagccatg tgtttcctct ttcatatctc ttatctaaat aaaaatccat aaatggcgtg
     3121 aatactattg accagattgg taaaagcatt cagtaaaaat aaaattgcta aaccaaaacg
     3181 tttcttccga aaggcttgaa tcgcacaaag aacacaaatc ccacagagaa atgctgtaaa
     3241 taaaccgaat aaacttctct ccatgcctaa ccatctcttc tttcataggt ttttattgta
     3301 aaatcatacg ggtttttctc gtcttttgga cgtaaattgg cgctttgtag ctgaaatttc
     3361 tccataggaa atgctttcgg aaaatacaca tcgccattaa attgaccgtg aatatctgtc
     3421 actattaatg tttcaatgta aggtgcaaaa gcagtaaaaa tttgtccccc accaatcaca
     3481 aatagtgtct gctcctgttt gttataccaa tctagaacat cttccacact gtgtaaaatg
     3541 gtaatacgtt cactctctag ttgataggtt ttatccgttg tcaaaacgat ggtgtgacga
     3601 ttgggaagag cacgtttacc catgccgtcg aaagttatac gtcccatcac catcgtgtga
     3661 cctgttgtcg tttttttgaa atgagctaag tcagctggca atgaccaagg aagtctatca
     3721 ccttttccaa tcaatccatt ttcatcttga gcccaaatgg caacaatctt tttagtcatt
     3781 ttctctcact ttccgtccta tcattctatc aaaaaaacat gaaaaatgca cttaccaagt
     3841 aggccaagcg caaattttta tcatgttgaa actatcaccg actcctcaga gatagggaag
     3901 attccgagat tcgtagaatg tgaatctcgc tggtgctgga aagcccccct catcttaaat
     3961 cgctaagtca aaattaagtt gcggtttaac tggcttcgaa agtctgagta tagactgttg
     4021 aaggttggaa atagcaagaa cgaagttctt cactgctaat ccagttaaat tgctaaatcg
     4081 aattttaact gcggtttaac tggattgtag tccaccaatt caaaatcttc tgcccgaata
     4141 tcaaagaaat tggtaccgtc aggaacattt aagaccaaac gtggctcaac ttcagatggt
     4201 gtgcgacgga gtaattcttc agcctgttca aactgattgt catagatgtg aagattgttg
     4261 atgaaataga aaaacttccc aaccttccag ccaaaatgtt tagcgatcat catctgaagg
     4321 gctacatact gcatagcgtt gatatgatgg gctaccaaca tatcatttga ccgttgagtt
     4381 agagttgcat ccagataaat ctccccatcc actcgccgaa cgtcaaacag ggtctgaaag
     4441 gcacatggca aaagacccgc ggattggtca aatgcttcat aatcccacaa agaaatcaca
     4501 ttacggcggt tccatggatt ttcctctaat tgcttgagga tttttgaaat gatgtcatgc
     4561 tttttcacga tagccccata gcgttcaccg attgtgcctg ttccttcaac ttcccagtca
     4621 ttccaatact ggacaccgta tttttcctgt aagacagaca ggtcattagt ctggtcttgg
     4681 taaatccaga gaatttcctt gatggccgac ttaattggaa taggtctaag tgttgtaata
     4741 ggaaactcgc ccttagacaa gtcatactca gcaaaggcgc ctgtaacgta cttggaatta
     4801 gctacatttc catccttgta acgtgggcga gcattttctg aaaaaacgcc ctcttccata
     4861 atcttacgaa tgttttcttt aaaaataata tctgctttag tcatggtctt agtatagcaa
     4921 attctagcaa aaaactccag ttttgcaccg gagttctcat ttgaaaaaga atgaataaaa
     4981 attaaggtgg aacaaaccag atagggcagt tattaggctg aacaatataa aatacaaggc
     5041 aaccaagaga acactcaaca atatctgacg aacattttta gtgtaaatag ccgttggtaa
     5101 gctggctagt ccgaaaaatg gaatgataaa aaatgttagt ttaaaattca catttacaat
     5161 atcaaaccat tgtcctattg gcaaaaatag catgacgaag agaaaaattg cgataccata
     5221 caaaactaga tttaatcttt ttagtaaagt caggttcata accactcctt ctaggggcca
     5281 aatataaagt agccaatacc gaatatcaga ggaaatgaga ttattaagaa gatactaatc
     5341 aaaccagtcc acaatttttt ataatagata gatagtataa gaattagagc ccccagtaga
     5401 gggagaatca acatggttgc tacgtttccc cagctagacg ggaaaaacca gtcacgaatc
     5461 cagttatcaa ggaaaaaagc agataacaaa atcaataaac caagaatggt cagatagttg
     5521 attattttag acatgtttac ctgtttcata aggtgacact cctttctctt tacactttca
     5581 ttgtatgctt aaatactaca tttttcaata tatgtatata aagaaaatgt gacagcggaa
     5641 ttgaaaaaag cagagtttcc cctgctttta acgattattt caagacgagt gatgctgcgc
     5701 ccaatacacc tgcatcatta ccacgtgttg ccaagacaat ttgtgtactt tccttgattt
     5761 gtgggaagct attttcagca aagaccttgc gaacgccatc caataagaac tctcccgcag
     5821 ctgatacacc accaccaaga acgatgtagg caggattgag gactgcagca atgtttgcac
     5881 aagcaacacc taagtattct gagaagtgac ggtagacaat caaagccaaa tcatcgccct
     5941 cttttgccaa atcaaagaca tctttagccg ttacatcttg cccatcatca atcatttgtt
     6001 tcagttttgc atcgcctgcg tattgatcag catagcgacg gctgaggttg acaatacctg
     6061 tcgctgaagc aactgtttct agacaacctt tcttaccaca agtacatgca aatggctcat
     6121 caaagtcaac tgtgatatgg cccaattcgc caccagcacc tttgacacca cgaatcaagt
     6181 ttccagcagc gatgacaccg ccaccgacac ctgtaccaag cgtcataaag acaacgtttg
     6241 gattgttgtt tccagcacca acccattgtt caccgagggc cgctacgttt gcatcattgt
     6301 caataaagaa tggtaaaccg agcgcagatt caaactgctc tttgaccaat tgcaaggtct
     6361 tccagttgag gttataggct ccgataacag tgccagcttc actatccact acaccgggtg
     6421 agcccatacc aattcctaag aaatcgtcct ttgtcaaacc atgggtttca aatcgctgct
     6481 tgatactgtc aataatatca ggaacaatat gacttccatc atctaaaata tttgtcttga
     6541 tagaccattt ttcttgaatt tctccctcag tagtcaaaat ggccaattta acagaagttc
     6601 ccccaaggtc aataccgata atttttttag acataatcat cacctcaaat gtattttctt
     6661 tattataaca caatgcaaag gtttgcgtaa agccttttca aaaatttgta cggataaaaa
     6721 ttaattgctc tatcgaaaaa gatagagcaa aattaaaaat tgaatatgta agataaacct
     6781 tccaatggaa aagagcataa ctgtcgtaaa attactacct tctttcgttc cattatagag
     6841 aaaaagagta gaaataaagg taaatcccag agcaaacccc accatctgca agtcgtgata
     6901 agactgacta taaaaataca aggtgcttgt cagcaatatc atggatagga tagttaaaat
     6961 caagcgcaat gtattcattt ttttggtctt tagatagcta aacaaagccg ctcctaaggt
     7021 caccaagaga tagatgacca tatatgacat gacaagaact ttcatctagc cctccagttt
     7081 gctcagatac tcataccgct catatttttc caagagcagg tcgtttttct catccaattc
     7141 cttctgcaaa tcggacaatt ttgtaaaatc actaccacag gtcagcattt ccgcctcgat
     7201 tgccgcaatc cgctcctcca agccagcaat atcctcttcg atggttgccc attcctgctt
     7261 ctcaaagtag gacatccgct tcttgttctc tttgattttc tcggttttct cctttggttt
     7321 ttccaaggaa atggcagagc tggaagccag aaaggccttc tcatccagat agtctgtgta
     7381 gttgccaaag aaagtctcta taccgctatc ttcgaaagcc aagattttat tggctacctt
     7441 gtctaggaaa taacggtcgt gactaacggt aatgactgga ccagtaaagc cctgcaagaa
     7501 atgttccaag actgtcagag tcgctatgtc caagtcgttg gtcggttcat ctagtaagag
     7561 aacattgggc cgttgcaaga gaatcttcag caaataaagt cgcttcttct ccccacctga
     7621 caatttctca atcagggtac catgggtatt acgtgggaag aggaattgct ccaagagttc
     7681 tgcgatagaa accataccag atgtcgtctt agcttcttct gccacttcct gcaagaaatt
     7741 gatgacccgc ttgctttcgt ccaagccctt gatggtctga gaaaaataac cgatacggat
     7801 ggtttcacca atatctacct taccgctgtc tgcttgtaag tcgcctgcga ttagattgag
     7861 cagggtagat tttccttttc cattatcacc aacaataccg atgcggtcct tgttttgaat
     7921 gagcaggtta aagtctttta aaatgggctt atcaggatag gaaaagctga cattttcaaa
     7981 gttaatgacc tttttaccga tacgagaggt ttcaaaattg atttccaatt cgctatcgtc
     8041 tatcttgttg gctaaatcgc ctttgaggtc atggaaacga ttgatacgag cctgctgctt
     8101 ggttgcacga gcttgaggtt gtctgcgcat ccaagccagc tcttgtttgt agagccgctc
     8161 tttcttatgg cgaagggcgg catctcgctc gtcctgttct gccttcaagc gaacatagtc
     8221 ctggtaattt ccctgatatt cggttaagct ggcgcggtcc aattcaaaaa tccgtgtcgc
     8281 cacattgtcc aagaaatagc gatcgtgggt aataaagaga acagactttt tagtattttt
     8341 caagaaagtc gtcaaccact caatggtatc aatgtccagg tggttagtcg gttcatccag
     8401 caagagcaag tcagcattgc caaggaggac ttgggccaat tggactcgtc tacgtagacc
     8461 ccctgataac tcagcaacgg ttttgttgag gtctgttagc ccgagtttcg acaagacagt
     8521 cttgacctgg ctttcaatct cccaagcatt gagagaatcc atctcagcca tcaccttttc
     8581 cagtcttgct tgactggttt catcgtaatg agataagagc agctcgtatt cacgaatcag
     8641 ctgggtttca cggaggtcag atgaaagaac ggtgtctaaa actgtcttgc tttcatcaaa
     8701 atcaggttcc tgggtcagat aggcgatttt ataagcattt ttggtacgaa aaggtgatac
     8761 atctccgtca aaaccgatac gacttgacag aacatccaac aaagtcgtct ttcctgtacc
     8821 attgacccca ataatcccga tacggtcgcc ttgatggatg atgaaagata gatcagcaaa
     8881 gaccgtttta tctccgacag atttagtcag gtgttcaacg ataaaatcac tcattctcta
     8941 agattccttt cacaaatgtc ataatcgctt gctcttcgtt ttccagctgt ccttccacaa
     9001 tctggaattc cacctctttg agtagttctc ccaatactgg acctggtttg aggtcaaatg
     9061 ccttcatcag atgtcctcca ttgacaacaa tttcatgctt gtcgtggata gtcaaggctt
     9121 ggtcaatctt atcgattgct gcaaaatctg taacaaaacc ttgtgcctga tgaagttcct
     9181 ctaccaagta taagaattct ttgccatact tgaaacagat ttgcttggta acaggtcctg
     9241 cttggcggag ctgataaatc tctaccaact tgaccacgct gcgttggaaa tcattgctgg
     9301 ttttccattt tttcaggaag gacttgatgt tatcaatacc taggcagaca aagagcaggg
     9361 cccaagcttg ttcagatgtc gaaaagcgaa actcttctgt cagacttgtt agcatggcct
     9421 ctaattcatc actttttcca gctaaatcag gcaagaaatt gtaagccttg gaatcaatca
     9481 tagcgcgcaa gccttttcgc caaaaatccg ccatcaatag tttatcaaac tcgataaagc
     9541 tacgttccac cgagattttt tccaagagcg gtgcggtttg caccatagct tcaaaggtcg
     9601 tcggttcaat ctcaaagtcc aaggtcgctg caaagcgaaa acctcgcatg atacggaggg
     9661 catcttcgtt gaaacgctca gccgggatgc ctacagcccg tagggtgcgg ttttctaagt
     9721 cagtcatccc atcaaagagg tctacaattt gagcctcttc atccagggca aaggcattga
     9781 ctgtgaagtc gcgacgtttg agatcctctt ctaaggaacg cacaaaggaa acctggctcg
     9841 gcctacggaa gtcgacatac tcctcctctg tccgaaaagt cgtgatttca tactcctttt
     9901 tcccctctaa tactagcacc gtaccgtgtt caattccgac atcaatagtc cgtgaaaaga
     9961 tttgtttcgt ttcctgaggg tagctggatg tcgcaatatc gacatcgtga ataggtctgc
    10021 ctaaaatggc atcccgcacg gagccaccaa caaagtaagc ctcgaagcca gctgctttaa
    10081 ttttctctaa aatcggcaaa gcctcctgaa actcagaagg cagattgttt aatttcataa
    10141 taagtgttcc aaaccataaa cgagttgtga gcgtttgact acctctttaa tgccgagatt
    10201 gacaccgccc ataaaggaaa tacgatcgta agagtcatga cgaatggtca atccctcgcc
    10261 ctgtgcccca aaaatcactt cctgatgggc aacaaggcct ggcaagcgta ctgagtggat
    10321 acggaaaccg tcaaatgctg caccgcgagc gccagcaatc agttcttctt catccgctgc
    10381 accttgagtc tgtgactgac ggacttgtga aatgagttcg gccgttttga cagccgtacc
    10441 actcggtgca tccttcttct tatcgtggtg taattcaatg atttcaagat ttgggaaata
    10501 cttggctgcc tgtgctgcaa attgcatgag caagatagcg ccaatagcaa agttaggagc
    10561 aatcaagccc cccaagccct tctcagctga caaggctgtc aattcctcga tttcttcagg
    10621 ggtaaatcct gtcgttccaa ccacaggtgc gaaaccattt tccaaggcaa aacgggtgtt
    10681 ttcataggta aattttggcg ttgtaaaatc cacccagaca tcagcttcca gactggcaac
    10741 ttcttctttg gtcttgaaaa caggaacacc gtctacttct gtttctgtcg caaatggatc
    10801 taccaaggca gccagactaa gtgctgcgtc acctttgacc atctcaacag ccgttgagcc
    10861 catttttcct ttgaatcctg cgataattac cttaattgtc atgcaaactc ctattcaata
    10921 atgggagaaa taccaaaggc cactgcccct tctcccaagt gcgtaccgat gaccgaacca
    10981 aatgacacga ttggtaaatc gctaccgaca cctgcttctt ccaactgccg tttaaagttt
    11041 tcagccttct gaggtgcgtt ggcgtgtatg atagcaatct gatactgtcc ttcggtcgtt
    11101 tgttcttgga ggatttccaa gaggcgttta atggccttct tctccgtccg aactttttca
    11161 tacacttcta tcttaccctc acctgtaaaa tacagaatcg gtttgatgct caaaagattg
    11221 ccaagcaagg ctgcaccatt ggacaagcga ccacctttta ccaaatgatt gaggtcatca
    11281 accatgatga aggctgtagt cttcccaatt tcttggtcca atttcccagt aatctcttca
    11341 aaactaagtc ctgcatcagc ccatttgaga acattttcga ccatcatacc taaaggagcc
    11401 gatgtgattt tggtatctgg aaaggcaacg gttaatcctt caaattcatc agccaaatat
    11461 tgaatatttt gataaaaacc tgaaatacct gatgacaaga ataagccaag tgcgtgtgta
    11521 tagcctttct ctgttaattt agccagaatt tcttctagtt ccatcaaact cggttgactt
    11581 gttttaggta attctttcga tgaagccatt ttttgataaa actcttcaac cgtcaaattt
    11641 tgtccttcga tataattttc cccatcgatg ctgactggaa tacttaggac aaacaggtca
    11701 tcccgctcaa tactttgaac attcaaaaca gccgatgagt cagttataac cgctaatttc
    11761 atattaaaac tccaaattca ctcctggtgc atcaaaggcg atttcagtaa cctcataagt
    11821 cattcgtttt aaaatgtcca aaagaggctc taccaaaaca cgtttttcct catcagtaaa
    11881 ttcagttggc tcttctacca atcgatttgg taagtgaacg gcctgactca tggcacctga
    11941 aatcacaaaa tgatctagta caatcataaa gcgcaaaatg gtaatcatag atgttcgatt
    12001 ttctgcacga ttttgctcaa tcaattgaaa gtcaactttc aattttgttt ccggaattcc
    12061 gttctctttt tcccacgcgt gattgcgggc atcaaaatga tactgattga caaattcttt
    12121 atcgcgaatg atttccattt caagactcct ctaataacaa taatactcac attataccat
    12181 aatcctcgtg aaatagctaa aaaaccttgc cagaagcaag gtttcaatca aaattattta
    12241 gctttacgaa gtgctccgta aaggacacct gatacaaccg caccaatcaa aacataggcg
    12301 atgtaaagca atggattaga tgtcaaagcg ataacgaaga taccaccgtg aggagccatc
    12361 aattggatgc ctgacaaacc aaccaaggca cctgcaaggg cagaaccagc gataaagctt
    12421 gggattgcac gagctgggtc agcagcacca aatggaatcg caccttcagt gatgaatgaa
    12481 agacccataa caatgtttgt caaacctgag ttacgctctt cttgtgtgaa tttgtctttg
    12541 aaaagaaggg ttgcaacgaa tactgccaac ggtggaacca taccacctgc cattaccgct
    12601 gccatggcaa cagaaccacc atctgcaaca gttgctgcaa gtgtacctgt accgaagaca
    12661 taagctgcct tgttgactgg accacccata tcgactgcca tcattccacc gaggacaagt
    12721 ccaaggagaa tagcagagct accttcaaga cctgcaagga agttgttcat acctgtgttg
    12781 attgctgcca ttgggatgtt aacgaagaac atcaagaaac cagtgattgc tgttcccaaa
    12841 agtggcaaga gcaagatagc gttcaaacct tgaagtgatt ttggaaggtt gcgcaaagcg
    12901 ttgcgaagaa cgagcactac accaccagca aggaaaccac caacaagggc acccaagaaa
    12961 ccagatgata cacctgcaag agcaagcgtt tcttcaccac cagctgcgta aggaatttta
    13021 ccgaacgcaa gaccgctact agcaattgca ccagctacga aacctgcaac caaacctggt
    13081 ttttcagcaa tcgagtaagc aatataacct gctagaagtg gcaacatgaa gccgaaggct
    13141 gctccaccaa tcttcatgaa catagctgcg atttcatggt atgaaccaag actaccaagg
    13201 ctgtcttgtg gcacacctag agctccatcg aataggaagg caagggcaat caagataccg
    13261 ccaccgataa cgaatggcaa catttgagac acaccactca tcaagtgttt atagaacgct
    13321 ttgccaagac tgagtttttc tgaagattcc acagtagctg ctccttctga cgcagtgtag
    13381 gctgatgctt taccatccaa gataaggtta attaattctt ctggttgttt gattccagct
    13441 gcaactggac gagataccaa aggtttgcca ttgaagcgag gcatatcaac agccttatct
    13501 gctgcgatga taacacctgc tgcattctta atgtcttcag cggttagttt gtttccaaca
    13561 cctgaagcac cgttggtttc aaccttgatg tcaacaccca tctcagcagc ttgtttctta
    13621 agtgcttctt ctgccatgta agtgtgggcg atacctgttg tacatgctgt cacagcaacg
    13681 ataaatggac ggtcaccact tggtgctgca acaacttctt cagcagtctt atctgctgct
    13741 tcagctgcgt caaaaactga aatgacttct tctgggctag acacaccacg aagtttgtca
    13801 gcaaatccag gcttcatcaa gtatttagac aattcagcaa gggcagccaa gtgtgtatcg
    13861 tttgcacctt ctggagctgc aatcatgaag aacaaatcgg ttggttgacc atcaagactt
    13921 gcgtagtcaa ctcccttgtt tgattttgca aagagaacag ttgcctcttt tacagccgca
    13981 ttcttagcat gtggcattgc gataccgtcg ccaagaccag tagttgtttg cgcttcacgg
    14041 ttcatgatac ctgttttgaa aacatcaaaa tctgtaacat atcctttatc aaccaaacta
    14101 gcaatcattt catcgataac tgcttccttg cttgtcgctt gcaaatcaag caacatgaca
    14161 tcttttctca aaacgtcttg aattttcata gtgtttctac ctcaactttt tcataagttt
    14221 ccttaataaa ttcgatactt gccaaatcat ctgaaaaggc tgttgccgta ccgcaagcaa
    14281 ctccccattt tagggcttca attgggtctt gtgagcgaac gtattcacct gtaaaacctg
    14341 ccaccatgga atctccagct ccgacagagt ttttcactgt acccttgatt ggtttagcaa
    14401 agtaagtagc tggtggagtg accaacaaag ccccatcccc tgccatggaa atgatcacat
    14461 tctgagcacc catttctaag attttcttag cgtaggtttc aatgtctgca atgccattca
    14521 attcgacgtt gaagattgct tcaagttcat ggttgtttgg cttgaccaaa agtggctggt
    14581 gtgctagtga gtctaggagt gtttgacctt caaagtcaca gacaacttgc gctcctgctt
    14641 ttttcgccac aggaatcagc ctattgtaga cttcgtttcc aagactagct ggagcagacc
    14701 cagcaaagac aacggtgtct tctttggtca atcctgctaa gaccatttct aattcggcca
    14761 actgtgtatc tgtcacaatc ggacccaaac cgttgatttc tgtttcttgg tcagctttga
    14821 ttttcacgtt aatacgtgta tcttgatcaa cctgaacaaa atcagtatca attccttcgg
    14881 caatcaatcc atctttgatg aactgacctg tgaatccccc aaggaaaccc gttgctgtat
    14941 tcggatagcc caagcgcttc aaaacacggc taacgttaat tcccttaccg ccggcatact
    15001 tatcgtcgct ctccatacga ttgacactgc ccgtctcgac atcttctaaa cgaacgatat
    15061 agtcaatcgc tggattgagc gtaactgtat aaatcatacc tcgattaccc tcgttttctc
    15121 ttttatgatg tccaacaaac tgctttctga agattggcag ataatgttgg atttttcgat
    15181 tgccgcaact ttaacaaagg agaattgacc aattttagaa gcatctgcca aaacatagct
    15241 ttctttggca ttgtctatga tagtgcattt gatggtcgct tcttcaatat ctggcgttgt
    15301 aaaatagttt ttatcaatac cattcatccc cagaaatgct ttatcaaaat tgagctgtcg
    15361 aatttgttcc aatgctactg ctccaacgga agcatctgtt gattgcttaa caaaaccacc
    15421 tataatgatt gtttttatct tgcgttcaac cagcctcact gcgtggtgaa tagaattggt
    15481 aacgactgtc agattttcct gctgaagata atcaatcagt acaccggttg ttgtacctgc
    15541 atctaaaaaa attacgtctc cgttaacaat ttgtcgagca gcactttccg caatctctcg
    15601 tttttcttga acgtttttga cagatttttc tagaatagac tcttcgagtt gcaaattccc
    15661 tggcgcttca gcaccgccgt gtacacgacg aagcttacct tcgttttcca actcatccaa
    15721 atccctacgt acagtagact cagatgtatc aagaacttcg attaattcct ctagccgaac
    15781 aaactgttga gagtgtattc gctctaatat aatctgtttt cgttctgatt tgagtatgtt
    15841 caacacctcc tgcaaccgtt tacaaaaatc attatacacg attttctgcc attgtcaatc
    15901 attttctatc attttctttc aaaaaacaaa aaaactagca gaatttacgc ttccactagt
    15961 ttctcaatca tttttttcat catgtccatt tcttctggac ggccgataga caggcgaata
    16021 tgcccttcta atttacctgt tggataatat ttgaaattcc aatcctgtgc caaggcttgc
    16081 tgataaaatt cttctgccca cgttgcttta aacgttacaa aactagcctg actaggtaga
    16141 acttgacagt tatctaaccc ttgcaagaat aaaatcattt cttctcgcaa attctgaatt
    16201 acttccactg tttctaaaac cttatctgta taattcaatg caacggctgc catttttgca
    16261 gtcaagtttg acaagctgaa tgggggaatg accttgtcca attcataaat taactcttcg
    16321 cttcctaccg caaagccaac tcgtaaacct gcaagtccaa aagcctttga taaagtccgt
    16381 aaaactaaaa cattgtcaaa ttgttgcaga cgactgatga agctttcgac atttgcaaat
    16441 tcaatgtaag cctcatctac aacgagtagc cctttaaaag aaatagccaa tttctccaaa
    16501 tcttctagtg aataagctac tgaagaagga ttgttaggat tggaaagcat gattatcttt
    16561 gccttcacct cctccgcacg cgccaacaat ttctctactg gcaggacgag tgtatcgttt
    16621 ttttcttcta aatcaatggc ttcaaaacgg ctaccatgca tgtgattata ggtttcatac
    16681 atgaagaagt ctggattgac agtcaaaaaa gtatcatcct tttccataaa ggtggaaaca
    16741 atcatgtgaa taaggtgatc agagcccaca cctaccgtca cttgtttggg attaactcca
    16801 agataggtcg catatttctc aatcagttcg gagtaagtgt tatcaccata aaaacttaat
    16861 tgattgacat ccaaattttc caaagtctct tgtggcaaaa aagcccaatc aatgatacga
    16921 ttttcgttat ttcctaaatc aaatcttgcc ttttgtttga ttttataagg ttggtaatgt
    16981 tcaaatacct tgcgtttcat catttctcct tctagcaaga aaaacacagt ctaatcaact
    17041 gtgtcttctg ctttgatttt ttcaaaaata gttaactctt cagctgtaaa gttgtagttt
    17101 tctaacaagt ctggacgacg ttgataggtt ttgcgtagac tctcttccaa acgccattta
    17161 cgaatatttt catggtgacc gctcattaat acatctggaa ctaccattcc acgatactcg
    17221 tatggtcggg tgtattgagg atattccaat agccctgatg aaaaactatc atccgtatga
    17281 ctgacttcct tgccaataac ctctggaatc aggcgaacgg tagcatcaat catggtcata
    17341 gctgccaact ctccacctgt caggacataa tctccgagag aaatttcatc tgttactaag
    17401 gtcttaatcc gctcatcata tccttcatag tgaccgcaaa tgaaaatcag ctgctcttcc
    17461 tgtgccaatt cttcggcata ggcctgattg aaagtacgcc cagcgggatc caataggata
    17521 acacgtggct tggtttgttc aatgctatcc atggtatcaa aaatcggctg ggcaaggagc
    17581 aacatacctt gtcctccgcc atagggttca tcgtctacat ggcgagcctt ttcagcattc
    17641 tctcggaaat tgtggtagtt gatttctagc aaacccttgt cacgcgcctt acccacaata
    17701 gagtgttcta gaggtgcaaa catctcaggg aagagggtca aaatatcaat tctcatcgtc
    17761 taggccctcg agcaattcca catcgacacg gttatttgga atatcaatgt tcaagacaac
    17821 aggtggaata tatggcaaga gcaggtcttt cttacctttt cgtttcacca cccagacatc
    17881 attggcacct ggctgcaaga tttccttgat ttgtccgatc agaatatcat tctcatagac
    17941 atctaagccg ataatttcat ggtaataaaa ctcaccatct tcaaggtcgg tcaaattttc
    18001 ctcggcaatt ttcaaactaa agcccttgta cttttcaata tcgttgatat ggtacatgcc
    18061 cttaaactta ataatatcaa agttcttagc cttacggtga ctagcaattt ccacttccat
    18121 ggcaaactga tccttgtcat caaaaagtgc aagctttgcc ccttttttaa aacgttcttc
    18181 agcaaaatcg gtcacagaca aaacacgcat ttccccttgt aggccttgcg tgttaacaat
    18241 ctttcctacg ttaaaataat tcataatttc tccatttgat tttctatcct tttattttaa
    18301 catgagcaag atattttcac aagagagaaa aagccggatg cctccgactt tcatagttaa
    18361 tttatttcac agacaaatga gaatgagcta ttttgatcaa gcgcaaattg agagctattc
    18421 cgcagacaaa aatccctgaa ataagaccga tccaataggc ttctggaccc atttggaaaa
    18481 atctttcaag caagaatgcg actgggaagg tcatggacca ataggcaacc aaaccaagta
    18541 taaatggaac agtcgtatcc ttgtaaccac gtaaaatccc ctgaataggt gctgtaaagg
    18601 catctgctaa ctggaacatg agggcaaagc tcaggaaatg cgaggtcaga cggataaatt
    18661 ctgcgtcatt accataaagg taggcaactt tggagcggaa aaaatatagg aaagttagcg
    18721 tcaaacctgc aaagcctagt gctactaagc gtcccagacg gctgtaggct ttcacatctt
    18781 gtggtcgttt agcgcctact tcataagcaa tgacaatagc tagggctgag gataccgata
    18841 tggaaaggca tataataagg ttgcaaagtt catagctgac tggtgggctg ctataatctg
    18901 tgctgaaaat tttgccatgt agagccctac tactgcaaaa attgctactt ctgcaaagac
    18961 ttgtaaaccg atgggaagac cgattttcag tccttctttc agtaaagacc catcaatcgg
    19021 actccaccgc caaatctgat aagaagaaat agtcttattt ttgcacatga caataacgat
    19081 tactagcaat accgcccagt aagctaaagc agtacccaat ccagctccag ctccgcctag
    19141 ggccgggagg cccattttcc cataaattaa gagatagtta aatagactgt taaatgggac
    19201 aaggagcaac atgaggtaca tggatagctg agtcaagccg agggcgtcga aaaaagagcg
    19261 acagacacta aagagcaaga gaggcaggat accaatggaa ataaaataga ggtactgccg
    19321 accaacttga aaaacagatt catcaagtcc aaactgagcc aagacgggaa cagcgataaa
    19381 taggatcgag cacaagagta aaatggttaa tccaatagat agatagacaa actgatgaaa
    19441 ctcttgtcga atctttgact tctctccttg tcccaaatat tgggcaataa tcgagaccaa
    19501 tgcagataca atccctgtaa gaaatgaaaa aagcggattc caaagacttg ttgccatgga
    19561 aacacctgcc aaatccatag tactatactg accagtcatc atggtatcga taaaggatgc
    19621 ggagtaatta gcaaattggt aaattaaaat gggcaaaaat attttgataa agagccagag
    19681 cttctctttg ttatttcttg tttggtacat acttattctc tttcaatttt atataaatat
    19741 tgtaacaaga aaaggacctg cattgcaagt cctctttgac tagatagagt caccattcca
    19801 gatagagttt ttcacgataa catagtccac atgcttcaag ctggtaatgt cacgtcctcc
    19861 tgcataagaa atagatgact gcaaatcttg ctccatttca accagagtat cttttaaatg
    19921 tcctttggca gggagtaaga ttttcttacc ttctacgttt ttataagcac ctttttggta
    19981 ttcagatgct gaaccgtagt actctttgaa tttctcacca tcaacttcaa ttgttttacc
    20041 tgggctttca atgtgaccgg caaagagcga accaatcatg accatgcttg caccgaagcg
    20101 gatggatttg gcaatatctc cgtgggtacg aataccaccg tccgcaataa ttggtttgcg
    20161 ggcagctttt gcgcaccaac gaagggcagc caactgccaa ccacctgtac caaaaccagt
    20221 cttaaccttt gtaatacata ctttacctgg accaatacca acttttgtcg catctgcacc
    20281 agcattttct agttcacgaa ctgcttctgg agtaccgaca ttacctgcaa taacaaatgt
    20341 ctcaggcagt tctttcttga tatgttgaat catcttgata acactttctg catggccatg
    20401 agcaatatca atggtgataa actcaggggc atcagctttc aagctagtca caaactcata
    20461 ttcatattct tttacaccaa cagagataga agcaatcaaa ccttgctcgt gcatgcgttt
    20521 gataaatgga atacgaccag cttcatcgaa acgatgcatg atgtagaaat aaccatcttt
    20581 ggcaagcatt tctgccacat cttcatcaat aatagtctgc atattagctg gaacaactgg
    20641 taatttaaag ctatatttcc caagagtcac tgttgtatct gcctcggaac ggctattgat
    20701 gatacattta tttggaatga gctgaatatc ttcgtagtca aaaactggag tttcgttgaa
    20761 catgcttcta cctctttttc ttaacattgg aacagaaaaa cggtttgttt ttcgtatttt
    20821 ttcctta
//
LOCUS       DBNFCO010000035        20436 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.035, whole genome shotgun sequence.
ACCESSION   DBNFCO010000035 DBNFCO010000000
VERSION     DBNFCO010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 20436)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20436)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20436
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.035"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            299..2950
                     /gene="adhE"
                     /locus_tag="AC1PIV_001062"
                     /gene_synonym="adhC"
     CDS             299..2950
                     /gene="adhE"
                     /locus_tag="AC1PIV_001062"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006066 - alcohol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HIP6612093.1"
                     /translation="MADKKVVSPEEKLVEARKHVDELVQKGLVALDEFRKLGQEEVDY
                     IVAKASVAALDKHGELAMHAFEETKRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLIALKTRNPIVFAFHPSAQESSAHA
                     ARVVYEAAVAAGAPENCIQWVTKPSMEATSELMKHDGIATILATGGNAMVRAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEVYDEFVAE
                     FKSYKTYFVNKKEKALLEEYCFGVKANSKNCAEGKLNADIVGRPAAWIAEQAGFSVPE
                     GTNILAAEVAEIGEKEPLTREKLSPVIAVLKVEGRAEGLEAARQMVEFHGLGHSAAIH
                     TEDAELAKEFGTIVRAIRVIWNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSISDNVS
                     AMNLLNIKKVGRRRNNMQWFKVPSKTYFERDSIQYLQKCRDVERVMIVTDRAMVELGF
                     LDRIIEQLDLRRNKVVYQIFSDVEPDPDITTVYKGTELMRTFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPTVDFHDLVQKFMDIRKRAFKFPELGKKSKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPAHVTADTGMDVLTHATEAYVSTVA
                     NDFTDGLALQAIKLVFENLESSVKNADFVSREKMHNASTMAGMAFANAFLGISHSMAH
                     KIGGRFHTVHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYKADEKYQDIARLLGLPC
                     STPEEAVAAYAQAVYDLGERIGIQMNLKAQGIDEKELKEHSRELALLAYEDQCTPANP
                     RLAMVDHMQEIIEDAYYGYKERPGRIK"
     gene            3364..4848
                     /gene="thrC"
                     /locus_tag="AC1PIV_001063"
     CDS             3364..4848
                     /gene="thrC"
                     /locus_tag="AC1PIV_001063"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004795 - threonine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HIP6612094.1"
                     /translation="MTLVYQSTRDAKNTVSASQAILQGLATDGGLFTPLSIPTVDLDF
                     SVLKDASYQDVAKLILSAFLDDFTADELDYCINNAYDSKFDTSVIAPVVKLKGQYNLE
                     LFRGSTIAFKDMALSILPYLMATATKKHGLENEIVILTATSGDTGKAAMAGFADVPGT
                     QIIVFYPRDGVSKVQELQMTTQTGANTHVVAIDGNFDDAQTNVKHMFNDEALRAKLAA
                     KKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIAAGDKVNFTVPTGNFGNILAAY
                     YAKQIGLPVGKLICASNDNNVLTDFFATGVYDKNRTFRVTTSPSMDILVSSNLERLIF
                     HLFGNDAAKTAELMEALNTAGQYDIQGADAEILSLFAAAFATEEETAAEIKRVYDESD
                     YIEDPHTAVASAVYKQYVEQTGDQTPTVIASTASPYKFPVVAVEAVTGQSGLSDFEAL
                     AKLHEISGVDLPPAVDGLETAPVRHNTVVAAADMQTEVERYLGV"
     gene            4977..6737
                     /locus_tag="AC1PIV_001064"
     CDS             4977..6737
                     /locus_tag="AC1PIV_001064"
                     /EC_number="7.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0042883 - cysteine transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HIP6612095.1"
                     /translation="MAQEQEKISREKKKALLKRLKERIKPKMKLVYLAAFLSWVQFLM
                     RIISFYLIAKGFVSYYEGGQVDLVRFVLILLGLNAFGYGVALIAKRLQGLGSQFARDS
                     LKQSFFEVLLAKDGQFASKATAADVFNIASQGIDSLDTYYSYYMASSLRTQFNCATVL
                     LLVFLIFPLGAVIFILALPLIPISIIAMQKRSKRIMNRYWGSYMDVGNLFLDDLKGLN
                     TLYSYQADATYEKTFNEQAEDFRDATMELLSFQLQAVGYMDAVMYLGIGLSGFVAVNS
                     LAAGNLSLFSMLFFVLIATEFFAPIREQGYGMHLVMMNTKMADRIFGFLDSMTAEQEI
                     DSVHVPAFDSLKLEDLAFAYGEKPVLEDISMTMPAGKVYALAGESGQGKTTLAQLLLG
                     RLRADKGAIYLGEQEISGISKLSLNEQVLYVSGQSTLLNQSIYHNLRMACDWSKEDIL
                     AWADQHGVLQFVKNLPDGLDTIVGDDGAFLSPGQRQQVICARAVLAKRSLYIFDEVTS
                     SVDQDNEGLIYDLIDLVAKDAIVIIITHKMKQVEQADDILFLSAEGAVTGNYATLYQT
                     SLAYGQLVDQQRELEEAVYG"
     gene            6730..8391
                     /locus_tag="AC1PIV_001065"
     CDS             6730..8391
                     /locus_tag="AC1PIV_001065"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding/permease
                     protein"
                     /protein_id="HIP6612096.1"
                     /translation="MDKKEMPTRVLIPRLLQSMKHLLPRIAVAVCFAVLGQVVTIAIP
                     VMLVYLAFNALTGNPAPLWTLGILILLALLRGAFRYGEHYFGHYVAFHTLAAYRRLIF
                     AKLRALAPGKLDRQDSGSLLKMIGEDIEALEVFFAHTIAPICTGILVALGLTVYFGLS
                     SWGLAFLALVTYALLAIAIPNQFAQQLQPLLKEQNASRKGYVSYFIESLKSMKDLMQF
                     QQTDARFANLTQKSQEVNGQERRVAQTNFMQYAVSFLVVGLSIMGFAWLTFDLVGSQS
                     LDLATGVALLVSFISSFAPFLELSRLPLGFKRAMNAGRNIYALLDEKEAERTGELVEV
                     SVTDIAIEQLDFDYDVRETGLYRNLSVQFEQGGIIGLVGESGAGKSTLMKLIMRWYDW
                     QQGQIRLSGLDSRQVDKAHLQGAFAYVPQVPQIFRQTIRENLVLGRTDISDETIMDLA
                     EKCHMKERILAAPQGLDTLVEASDFSAGEGQRLELMRALLKNADCYIFDEPTSNLDSL
                     NEARFIQLVKEHCQGMVFLISHRSSTMACADTIFRLEDGQLVKEK"
     gene            8392..8985
                     /locus_tag="AC1PIV_001066"
     CDS             8392..8985
                     /locus_tag="AC1PIV_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HIP6612097.1"
                     /translation="MKKLQVKDLMVTGAFAALYFVCVGLGTLLSLVFDRSGNMMYAPA
                     GAALLAGPVYMLLVAKVGKFGSISLVGAVMACFFFLSGYMTAAFLPSLTFGFLAEMVA
                     KSGHYKQKWTNLFSYIIFSFGNLGPIILMWFMRDAYEANLLARGKSAEYIARVMLDFT
                     PENVLWLSTTIILTALISGLFGQYMLQRYFKQSGYLS"
     gene            8982..9641
                     /locus_tag="AC1PIV_001067"
     CDS             8982..9641
                     /locus_tag="AC1PIV_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     component T"
                     /protein_id="HIP6612098.1"
                     /translation="MKLDARTKIILVIFTSFTYGMRLTILENAVLVLGLSLLFWFSGK
                     RKMAIMSPIAYSIFCLLSYITFLPAWLTHLLLVLTYTWPPLLAGHLLLMTTSGYELIH
                     GLRKWHLPEVFLLTLGVMFRFLPAIKQDARTICASLKVRGIFLRKRDVVCKPLQYMEF
                     FLVPLMMSLLRTAQELTVASLTKGLAVSTKSPAYIWSSWTVLDWSLCLCCLGFLILVR
                     L"
     gene            9605..11032
                     /locus_tag="AC1PIV_001068"
     CDS             9605..11032
                     /locus_tag="AC1PIV_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002941239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIP6612099.1"
                     /translation="MLSRFSDSRPAVTVKNVALTYSGADKPALQIEDLTIPEGQCVVL
                     CGQSGSGKSSFLKVLNGLTPEYYPAQLSGQIFLGDLDLQKSSLEEISRHIASVFQHPS
                     TQFFHSQVLQELVFPCENQGLSREEIENRLAWVMELFGLASLSQRTISSLSGGQQQRL
                     ALAVATMQGTDVLVLDEPTANLDQEGIVIVEDILKTVKSQGKTIIIAEHRLSYLSQLA
                     DRYLYFQDGQVVTDYLADEFLSRTEECRQDMGLRCYDSEPYGRAIAELADQFVNDKEG
                     LLVENLSVSQKENTLYEIEKLCLAPGQVVGLVGANGSGKTSLARYLVGLAEDKKSRIS
                     WQGQTLSSRQRLEKTAFVMQDVRLQLFAESVERELTLGRKNRAVDEHLVARFGLSDLL
                     ERHPVSLSGGEQQRVMIVASLLADKEIFIFDEPTSGLDLRRMQQVASALVDLKMKNKL
                     VLLISHDEELLNLVCDKIVDIKQLK"
     gene            11038..12315
                     /locus_tag="AC1PIV_001069"
     CDS             11038..12315
                     /locus_tag="AC1PIV_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HIP6612100.1"
                     /translation="MNKQTYKEILTIAFPAMGENLLQMLMGVVDSYLVASIGIVALSG
                     VSLANNILAVYQAVFIALAVAVSSRLAQALGEGGSEGIGGTASESVKFTVFIGLLLGI
                     FSVLAGPIVLTSLGAESEVVQAGGLYLILVGGGAPFLGLMTSLSAILRTLGEPRFPMY
                     ISLLSNVLNALFSAFAVFVLHAGVAGVAIGTVLSRLIGCSLLWSRLPISLKPWTWSFD
                     KELLRLALPATGERLMMRVGDVVVVALITSLGTATVAGNAIGETLTQFNYMPALGIAT
                     ATIILTAKHRQDKAMVRHIFRTSFGLSLLFMFLVAGVTYFAGSFLIDLYTKDIQAAQA
                     SQTVLFYAMLGVPFTAGTLIMTALWQGLGNARLPFYATTIGMWLVRIGIAYLLVTFFK
                     IGLSAIWIATILDNAFRSGVLFFQYRYSKQESI"
     gene            12505..13440
                     /gene="mvk"
                     /locus_tag="AC1PIV_001070"
     CDS             12505..13440
                     /gene="mvk"
                     /locus_tag="AC1PIV_001070"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004496 - mevalonate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HIP6612101.1"
                     /translation="MSVVGKANGKIILMGEHAVVYGHPAIAMPFSAVEIIAQVTAQGE
                     ALTVACDFYKGLVHKMPKIWESLKHAIRFSLYRIGAPTDPAIHIEISSTIPAERGMGS
                     SAAVAVAVARALFAYYEKELTDSELWDIVQSSEKIAHGNPSGIDAATTSGKSPVFFIK
                     HQPIEPFELKLHAHLVVADTGVTGNTLEAISDVADLLEKKPEAIKLVEELGNLTRQAK
                     EDLATDQAELLGSRMNQAHALLQKLGVSDPSLDKLVSLAQENGALGAKLTGGGRGGCM
                     IALARTAQDAQKLAHILDQAGARQTWIQYLGETND"
     gene            13433..14458
                     /gene="mvaD"
                     /locus_tag="AC1PIV_001071"
     CDS             13433..14458
                     /gene="mvaD"
                     /locus_tag="AC1PIV_001071"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HIP6612102.1"
                     /translation="MTKQIGIARAHTNIALIKYWGKRDKELFLPMNSSLSLTLDAFYT
                     DTKVVFDPELTADEFYLNGILQKEKEILKISRFLDLFCEYIGERAFARVESLNFVPTA
                     AGLASSASAFAALALATATALDLDLSPATLSTLARRGSGSSTRSLFGGFVEWGMGTGS
                     EDSMAHPIDDADWDIGMVVLAVNTGPKKIASREGMDHTVATSPFYTAWVETAKQDLVD
                     IKAAIASRDFEKLGQITEHNGMKMHATTLSANPPFTYWSADSLVAQEAVRQVREATGL
                     SAYMTMDAGPNVKVLCRASQMDELVAGLAKVFPREKIITSKPGPAAYVLSEKDWQASQ
                     TAFEKGI"
     gene            14460..15539
                     /locus_tag="AC1PIV_001072"
     CDS             14460..15539
                     /locus_tag="AC1PIV_001072"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HIP6612103.1"
                     /translation="MKVQVKIPGKLFLAGEYAVVEAGYPAVIAAVGQYLTVTIETSDQ
                     GSLHSSQKADLYLTWERKEGAVRIQGSHPYALIESAMQVTEAYLTAKGYACHGTYSLS
                     VQSDLDDQASGAKYGLGSSGAVTVATVKALLTYYGHQADALLTYKLAALTQSKLGMTG
                     SFGDLAASSFGGLIAYHSLDRSWLLGKMAELSLLDVVESDWQSLSISPIQLPQGLDLL
                     VGWTGSAASTDSLVSQMESQKSQTEKEQIHSQFLADSKTCVEQLIVACQTNDSVSARQ
                     ALSANRKLLQDFARGMGLVIETPQLSQLCDLAQTYGAVAKSSGAGGGDCGICLVDSKE
                     QKAAIETAWQEAGIFPLTLNIASRE"
     gene            15550..16647
                     /gene="fni"
                     /locus_tag="AC1PIV_001073"
     CDS             15550..16647
                     /gene="fni"
                     /locus_tag="AC1PIV_001073"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HIP6612104.1"
                     /translation="MFYLGEFGLDRKDQHVGLANQQYSATPAKDFTETLFVHHSLPQT
                     KVDEVDISTSVAGLDFAFPFFINAMTGGSKKTREINRLLGIMGHFGKIALASGSVSAA
                     IKDPSVAETFSVMRRENPYGIIFANLGAHHSVENAKRAVDLLEANAIQIHVNAPQEIV
                     MPEGDRDFTMWLKNIETLVREMEVPVIVKEVGFGMSRETVAQLASAGVQTIDVSGTGG
                     TDFAKIENARRTFNDYAYLEGWGQSTVTSLVEAMSVSEEVCPSLIASGGIKTPLDIVK
                     SLALGADLVGMSNHFLQYVKDGKGHRFDDGLQAIKVYQWQIAEIMTMLGAKNIAELRQ
                     KDLVLAPNVQNWCEARGIDWKAYARRSANVS"
     gene            complement(16742..18490)
                     /locus_tag="AC1PIV_001074"
     CDS             complement(16742..18490)
                     /locus_tag="AC1PIV_001074"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIP6612105.1"
                     /translation="MLSKTKQASVFLRLLSYLKAYRLLTVLALSFLLLTTVVRSLIPL
                     LASYFIDHYISTISETAVAILAAYFALYLLQMVLQYFGNLWFAKVSYSIVRDIRRDAF
                     GRMEKLGMAYFDQTPSGSIVSRITNDTESISEMFSGILSSFISALFIIVTTLSTMFAL
                     DWKLTSLIVLFLPVIFILVDQYRKRSAPIVAKTRSLLSAINSKLAESIEGIWIIQAFS
                     QEERLKEEFEAINQEHLDYASRSMALDSLFLRPALSLVKILAYALLMTYFGLDWSQAG
                     ISAGLIYAFIQYVNRLFDPLLDVTQHFSTLQTSMVSAGRVFTLMDQTIEEPLQLDRGA
                     KIDKGHIVFEDVYFSYDGKRQILDKVSFEVRQGQTIAFVGATGSGKSSIINVFMRFYE
                     FQSGRILIDGQDIRSFSQEELRSAIGLVLQDPFLFHGTIASNIQMYQDISQEEIEEAA
                     RFVDAAPFIEKLPEKYDHLVTERGSAFSTGQRQLLAFARTMASQPKILILDEATANID
                     SETEKTVQTSLEKMRKGRTTIAIAHRLSTIQDADCIYVLDKGKIIESGNHEELLALKG
                     HYHRMYQLQAGQLTAT"
     gene            complement(18480..20222)
                     /locus_tag="AC1PIV_001075"
     CDS             complement(18480..20222)
                     /locus_tag="AC1PIV_001075"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIP6612106.1"
                     /translation="MKIIKQLWWFFSLEKKAYLIGILSLCLVSLLNLLPASIMGQLID
                     QIASGQLTEHRLLLGVAGLILSALAMYGLRYLWRMNILATSYRLGKIMRARLFDHFMH
                     LSPSFFQQHRTGDLMAHATNDINALTRLAGGGVMSFVDATVTALVTLITMSLSISWQM
                     TLVAILPLPFMTLTTNFLGRRTHENFKASQAAFSELNNKVQEAVSGIKVTKSFGYQEQ
                     ETAAFQEVNQAAFLQNIKTMRYDALFNPAVLFFIGLSYLLTLLVGSHFISQGQVSLGQ
                     LVTFMTYLDLLVWPLMAIGFLVNISQRGDVSYNRIQTLLSISSEVIETDQPLPAPSNG
                     ELVYEISEFAYDNIPVLQDIQFQIKKGQTIGLVGLTGSGKTSLLKLLMREYDVINGQI
                     LLNQENIKNYKLADLRRLIGYVPQDQFLFATSITENIRFGNPDLSLNQVEEAARAVHV
                     YEDIQDMPDRFETMVGEKGISLSGGQKQRLAMARAMILNPDILLLDDSLSAVDAKTEH
                     AILETIKQERLDKTTIITAHRLSAIVHADLILVLEDGKIVERGRHQELLDEKGWYYDT
                     YMMQQLEKEESDAL"
BASE COUNT         5433 a         4310 c         5042 g         5651 t
ORIGIN      
        1 acaaaatttt caaaaaaatc tatttacatg gaagcgtttt cttgataaac tagtatcgta
       61 aatgttagag aaagaataaa tgataaagat ttgtcttact ttatgtattt ttcgaccaaa
      121 caaagcagaa acaaatctga acgttttctg aaaacaggaa aaagcaagcg ctttccaaaa
      181 caaaacagaa aaaatgtgaa aaaattaaca atttctcttt acaaataaaa taaaaaatag
      241 tagaataaca ttgtgaaaaa gttaacaaat agttagcaag tatatttgga ggaacacaat
      301 ggctgataaa aaagtagtat caccagaaga aaagttggta gaagcgcgca agcacgtcga
      361 tgagcttgtt caaaaaggtt tggttgctct tgatgagttc cgtaaacttg gtcaagaaga
      421 agtagactat attgtagcga aagcttcggt tgcggccctt gataaacatg gcgaattggc
      481 aatgcacgcc tttgaagaaa ccaaacgtgg tgtattcgaa gacaaggcta ctaagaactt
      541 gtttgcctgt gagcacgttg tcaataacat gcgccataca aaaacagttg gtgtcatcga
      601 ggaagatgat gtaacaggtt tgactttgat tgctgagccg gtcggtgttg tttgtggtat
      661 cacaccaaca acaaacccaa cttctacagc aatctttaaa tcattgattg ccttgaagac
      721 acgtaatcca attgtctttg ccttccaccc atctgcgcaa gaatcttctg ctcatgcagc
      781 tcgtgttgtc tatgaagcag ctgtggcagc tggtgcccct gaaaactgta tccagtgggt
      841 aacaaaacca tctatggaag caacgtctga gttgatgaaa catgatggta ttgcaacaat
      901 ccttgcaact ggtggtaacg caatggtgcg tgcagcttac tcttgtggta aacctgccct
      961 tggtgtaggt gcaggtaacg ttccagccta tgttgaaaaa tcagcaaaca tccgtcaggc
     1021 agcacatgac atcgttatgt ctaagtcatt tgacaacggt atggtctgtg cgtcagaaca
     1081 agcggttatc attgataaag aagtttacga tgagtttgta gcagaattca aatcttacaa
     1141 aacttacttc gttaataaga aagaaaaagc tcttcttgaa gaatactgct tcggtgtgaa
     1201 agctaacagc aaaaactgtg ctgaaggtaa attgaacgca gacatcgttg gtcgcccagc
     1261 tgcatggatc gctgagcagg ccggcttctc agtaccagaa ggtacaaaca tcttggcagc
     1321 tgaggttgct gaaatcggtg agaaagaacc attgactcgt gagaaattgt cacctgttat
     1381 tgccgtcttg aaagttgaag gtcgtgcaga aggtcttgaa gcagctcgcc aaatggttga
     1441 attccacggt ctcggtcact ctgcagctat tcatacggaa gacgcagaat tggcgaaaga
     1501 gtttggtaca atcgtacgtg ctatccgtgt tatttggaac tctccatcta ctttcggtgg
     1561 tatcggtgat gtttacaacg cattcttgcc atcattgaca cttggttgtg gttcttacgg
     1621 acgcaactca atcagtgata acgtaagtgc tatgaacttg ctcaacatca agaaagtagg
     1681 aagacgtaga aataatatgc aatggtttaa agttccttct aaaacatact tcgaacgtga
     1741 ctctatccaa tatctccaaa aatgccgtga cgttgaacgt gtcatgatcg ttacagaccg
     1801 tgccatggta gaacttggat tcctagatcg tatcatcgaa caattggacc ttcgtcgtaa
     1861 taaagttgtt tatcaaatct tctcagacgt tgagccagat ccagacatca caacggttta
     1921 taaaggtaca gaattgatgc gtaccttcaa accagataca atcatcgcac tcggtggtgg
     1981 ttcaccaatg gatgctgcca aagttatgtg gctcttctac gaacaaccaa cagttgattt
     2041 ccatgaccta gttcaaaaat tcatggatat ccgtaaacgt gccttcaagt tcccagaact
     2101 tggtaagaaa tctaagttta tcgcgattcc aactacctca ggtacaggtt cagaagtaac
     2161 accgttcgcc gtaatctctg ataaagcaaa caaccgtaaa tacccaatcg ctgactactc
     2221 attgacacca actgtggcaa tcgttgaccc agcactcgta ttgacagtac ctgcacacgt
     2281 tacagcagat actggtatgg acgtattgac tcacgctaca gaagcatacg tttcaacagt
     2341 agctaacgac tttacagatg gtttagcact tcaagctatc aaactagtat ttgaaaacct
     2401 tgaaagctca gtgaagaatg ctgactttgt atcacgtgag aaaatgcaca acgcatcaac
     2461 tatggcaggt atggccttcg ccaacgcatt cctaggtatt tctcactcaa tggctcataa
     2521 gattggtgga cgtttccata ccgttcacgg tcgtacaaac gctatcttgc ttccatacgt
     2581 tatccgctac aacggtactc gtcctgccaa gacagctaca tggcctaagt acaactacta
     2641 taaagcagat gaaaaatacc aagacatcgc acgtcttcta ggcttgccat gctcaacacc
     2701 agaagaagct gttgcagcat acgcacaagc agtttacgac ctcggtgaac gcatcggtat
     2761 ccaaatgaat ttgaaagcac aaggtatcga cgagaaagaa ctcaaagaac actctcgcga
     2821 attggctctt cttgcctacg aagatcaatg taccccagct aacccacgtc tagcaatggt
     2881 tgaccacatg caagaaatca tcgaggatgc ctactacggt tacaaagaac gtccaggtcg
     2941 catcaagtaa ggattttcgt cacgatacat cgttaaagct ccttgcctaa ctttagttat
     3001 gcctacgtcg ctttgccttg tctcgtttag aaaatcattc cttagtgatt tagattcgcc
     3061 ttcgtcaatc tgcctagaaa ggcttaggac tagaaaaagt ctaggtagga gtagtaaatc
     3121 gtatcctact cagttgaacg gagtaggatt tataggtaaa ttgcctccaa atatcgtaag
     3181 acaatcctct attgaaaaat aggggattgt ttgtttagaa ataatggtgg agattctgta
     3241 aaaagcgaaa gtggttggaa agttagggtt tagccgagaa aaagagactt ttctatctat
     3301 ctttcacaat tttctgtcaa tttgtggtag aatagaaaaa atagattttt tatgagggat
     3361 accatgacat tagtatatca atcaacacgc gatgctaaaa atactgtatc ggctagtcaa
     3421 gcgattttgc agggcttggc gaccgacggt ggtttgttta caccgctttc tattccaaca
     3481 gttgacttgg atttttctgt tttgaaagat gcttcttatc aagacgttgc caagctgatt
     3541 ttgtcggctt tcttggatga ttttacggca gatgagttgg actactgtat caataacgcc
     3601 tacgacagta agtttgacac gtcagttatt gccccagtgg ttaagctaaa aggtcagtac
     3661 aacttggagc tcttccgtgg ctcaaccatt gccttcaagg atatggctct gtccatcctc
     3721 ccttacttga tggcgacggc gactaaaaag cacggtttgg aaaacgaaat tgtcatcctg
     3781 accgcgactt caggcgatac aggcaaggca gccatggctg gttttgcgga cgttcctggc
     3841 acacaaatca ttgtcttcta tccgcgtgac ggggtatcta aggtccaaga attgcagatg
     3901 accacgcaga caggggctaa tacccacgtg gtggctattg acggtaactt cgacgatgcc
     3961 cagaccaatg tcaaacacat gttcaacgat gaggcactcc gtgccaagtt ggcggctaag
     4021 aaactccagt tttcatctgc caactctatg aacatcggcc gcttggtgcc acagattgtt
     4081 tactatgtct atgcctacgc tcagctggtt aagactggtg agattgcggc gggcgacaag
     4141 gtcaacttca ccgttccaac aggaaacttt ggaaacatct tggcagctta ttacgccaaa
     4201 caaatcggtc tgccagttgg caagctcatc tgtgcgtcca acgacaacaa tgtcctaacc
     4261 gacttcttcg cgacaggcgt ttacgataag aaccgtacct tccgcgtgac caccagtccg
     4321 tccatggaca tcttggtgtc ttctaacttg gagcgcttga ttttccatct ctttggcaat
     4381 gacgctgcaa aaacagctga gctgatggaa gccttgaaca cagctggtca gtatgacatt
     4441 caaggggctg acgcggaaat cctctcgctc tttgctgccg cctttgcgac ggaagaagaa
     4501 accgctgcgg aaatcaagcg tgtctatgac gagtcagact acattgaaga tccacatacg
     4561 gctgttgcct cagctgtcta taaacagtat gtggagcaaa caggggacca aactccgaca
     4621 gtgattgctt ctacagcaag tccttacaag ttccctgtgg ttgcggtaga ggcggtgaca
     4681 ggccagtcag gtttgtctga ctttgaagcc cttgcaaaat tgcatgagat ttcaggtgta
     4741 gacttgccac cagctgtgga cggcttggaa acggcacccg tccgccacaa taccgtcgtt
     4801 gcagctgccg atatgcagac tgaagtagaa cgctatttgg gtgtttaatt tcgatttatt
     4861 ttatgacaaa ctgctcattt tgaacagttt gttttctttt tgtggtttaa attaaaattt
     4921 acagataatt caaagaatga tatactatat aggaatactg aatagtgagg tggatgatgg
     4981 cacaagagca ggagaaaatc tccagagaaa agaaaaaagc cctcttgaag cggctcaaag
     5041 aacgcatcaa acccaagatg aagctggttt atttggcagc ctttctatca tgggtgcaat
     5101 ttttgatgcg gattatttcc ttttatctga ttgctaaggg ctttgtgagc tactatgagg
     5161 gtggtcaggt tgatctggta cgctttgtcc tcatcttgct ggggctcaat gcttttggct
     5221 atggtgtggc tctgattgcc aagcgtttgc aggggctggg ctcccagttt gcacgggatt
     5281 cgctcaagca gtctttcttt gaggttcttt tggccaagga tggtcagttt gcgtccaaag
     5341 cgacggcggc ggatgttttt aacatcgctt ctcaggggat tgatagcctg gatacctact
     5401 attcctacta catggcttcg tccttgcgga cccagttcaa ctgtgcgacg gttctcttgc
     5461 tggtttttct gattttcccg ctgggtgcag tcattttcat cttggccttg cctctgattc
     5521 ccatttccat tatcgctatg cagaagcggt ccaagcggat catgaatcgc tattggggtt
     5581 cctatatgga tgtgggcaat cttttcctgg atgacctcaa gggcctcaac accctctatt
     5641 cttatcaggc ggatgccacc tacgaaaaga ccttcaatga acaggccgag gacttccgcg
     5701 atgcgaccat ggagttgctc agctttcagt tgcaagcggt gggctacatg gatgcggtca
     5761 tgtatctggg gattggcttg tctggttttg tggcggtcaa tagcctagca gcaggcaatt
     5821 tgtccctctt tagtatgctc ttctttgtcc tcattgcgac ggagtttttt gcacccatac
     5881 gggaacaggg ctacggtatg cacttggtga tgatgaatac caagatggcg gatcgcattt
     5941 ttggtttctt ggacagtatg acagcggagc aggaaatcga ttctgtccat gtgcctgctt
     6001 ttgacagtct aaaactagaa gatttggcct ttgcctacgg agaaaagccg gtcctagaag
     6061 atatttccat gaccatgccg gctggtaagg tatatgcttt ggccggcgag tcagggcagg
     6121 ggaaaacgac cttggcccag ctgctcttgg gacgcttgcg ggcggataag ggagctattt
     6181 acttgggtga gcaggagatt tcaggtatca gtaagctttc tctgaatgag caggtcctct
     6241 atgtgtcggg ccagtcaacc ttgcttaacc agtctatcta ccataacttg cggatggctt
     6301 gtgactggtc caaggaggac atcttggctt gggcagatca gcatggggtc ttgcagtttg
     6361 tcaagaatct gccagacggt ttggatacga ttgtgggtga tgacggtgct ttcttgtcgc
     6421 ctggtcaacg ccagcaggtt atctgtgccc gtgcggtctt ggctaaacgc tccctttata
     6481 tctttgacga ggtgacgtcc agcgtcgatc aggacaatga aggcttgatt tacgacctca
     6541 ttgacttggt ggccaaggat gcgattgtca tcatcataac ccataagatg aaacaggtgg
     6601 agcaggcaga tgacatcctc ttcctgtctg cggagggagc tgtgacaggc aactatgcca
     6661 cgctttatca gactagcttg gcttacggtc aactggtcga tcaacaaaga gaattggagg
     6721 aagcagttta tggataagaa agaaatgcca acacgagtgc tgattccgag actcttgcag
     6781 tccatgaagc acctcttgcc acggattgcg gttgcggttt gctttgcggt cttgggacag
     6841 gtggtgacca ttgctattcc agttatgctg gtctatctgg ctttcaatgc ccttactggc
     6901 aatcctgctc cgctatggac cttgggaatc ctcattctcc tagctctttt acgtggtgcc
     6961 ttccgctatg gtgagcatta ctttggtcat tatgtggcct ttcatacgct ggcggcttac
     7021 cgtcgcttga ttttcgcaaa attgcgggcc ttggctcctg ggaaattgga ccggcaggac
     7081 agcggtagcc tgcttaagat gattggggag gatattgagg ccttggaggt tttctttgcc
     7141 cataccattg ccccgatttg tacagggatt ttggtggctc ttggtttgac ggtctatttt
     7201 ggtctatcta gttggggttt ggcttttctg gctctggtga cctatgctct tttagcgatt
     7261 gctattccaa atcagtttgc tcagcagtta caacccttgc tcaaggagca aaatgctagc
     7321 cgtaagggct atgtgtccta ctttattgaa agtcttaaga gcatgaagga tctcatgcag
     7381 ttccagcaga cagatgctcg cttcgccaat ctgactcaga aaagccaaga ggtcaatggt
     7441 caggagagaa gggtcgccca gaccaacttc atgcagtatg ccgtctcctt cttggtggtc
     7501 ggcttgtcta tcatgggctt tgcctggctg accttcgact tggtgggtag tcagagtttg
     7561 gacttagcaa caggagtagc cctgctggtt tctttcatta gctcctttgc tcccttcttg
     7621 gaactcagcc gtctgcctct tggtttcaag cgggctatga atgctggtcg caacatctat
     7681 gctcttttgg atgaaaaaga agcagagcga acaggtgagc ttgttgaggt cagcgtgaca
     7741 gacattgcta ttgagcaact ggacttcgac tatgatgtcc gagaaacagg cctttatcgt
     7801 aacctgtctg tccagtttga acagggaggc atcattggtc tggttggtga gtctggtgca
     7861 ggaaaatcca ccttgatgaa actaattatg cggtggtatg attggcagca aggccaaatc
     7921 cgcctgtctg gcttggatag tcggcaggta gataaggctc atttgcaggg ggcttttgcc
     7981 tatgtaccac aggtgccaca aatcttccgc cagaccattc gggaaaatct tgtcttgggt
     8041 cgtacggata tatcggatga aaccatcatg gacttggcag aaaaatgcca tatgaaagaa
     8101 cggattttgg cagcaccgca gggcttggat acgcttgtgg aggccagtga tttttcagca
     8161 ggagaggggc aacgcttgga actcatgcgg gccctgctca aaaatgcgga ttgctatatc
     8221 tttgatgagc caactagtaa cctagattcg ctcaatgaag cccgctttat ccaactggtt
     8281 aaggaacact gccagggcat ggtcttcttg atttctcata gaagctcgac catggcttgt
     8341 gcggatacca ttttccgctt ggaagacgga caattagtaa aggaaaaata aatgaagaaa
     8401 ttacaagtaa aagatctgat ggtaacaggg gcttttgctg ccctctactt tgtttgtgtt
     8461 ggtctaggaa ccttgttgag cttggttttt gatcgttcgg gtaatatgat gtatgcacct
     8521 gcgggagcag cccttttggc aggacctgtt tatatgttat tggtagccaa ggttggtaaa
     8581 tttggttcaa ttagtctggt tggagcagta atggcctgtt tctttttcct atcaggctat
     8641 atgacagcgg cctttctccc aagtttgacc tttggttttt tggcagaaat ggtagcgaag
     8701 tcaggtcact ataaacaaaa atggaccaat ctttttagct atatcatttt ctcttttgga
     8761 aacttaggac ctattattct tatgtggttc atgcgagatg cctatgaggc caatcttttg
     8821 gcacgtggaa aatcagcaga atacatcgct cgtgtcatgc ttgatttcac tccagagaat
     8881 gtgctatggt tgtcaacgac cattatctta acagctctta tcagtggttt gtttggtcaa
     8941 tatatgcttc agcgctattt taaacaatca ggttatcttt catgaaatta gatgctcgta
     9001 caaaaattat tctcgtcatc ttcactagtt ttacctatgg gatgaggctt acaatattag
     9061 aaaatgcagt gctggtctta ggccttagcc tgcttttctg gttttctgga aagcggaaaa
     9121 tggctataat gagtccgata gcctattcta ttttttgtct gttgtcctat attacatttt
     9181 taccagcatg gctgacgcat ttgttacttg tattgaccta tacatggcct ccgcttttgg
     9241 caggacatct attactgatg acgacaagtg gttacgaact cattcatggc ttgcggaaat
     9301 ggcacctgcc agaggtattt cttttgacgt tgggagtaat gtttcgtttc ctacctgcca
     9361 ttaaacagga tgctcgtacg atttgtgcct ctttgaaggt tagaggaatt tttttacgga
     9421 agagagatgt ggtttgtaag ccactccagt acatggagtt tttcttggtt cccttgatga
     9481 tgtctctctt gcgaacagct caggaattga cagtagccag tctgacaaaa ggtttggctg
     9541 tgtctacgaa atcacctgca tatatttggt cgtcttggac cgtgctagat tggagtcttt
     9601 gtttatgttg tctcggtttt ctgattctcg tccggctgtg acggtaaaaa atgtagcatt
     9661 aacttattca ggagcagata aaccagcctt gcagatagag gatctgacca ttccagaagg
     9721 acagtgtgtt gttttatgtg ggcagagtgg ttctgggaag tctagttttc tcaaggtatt
     9781 aaatggtttg acgccagaat attatcctgc tcagctttcg ggacaaattt tcttagggga
     9841 cttggattta caaaaatcta gtctggaaga aatatctcgg cacattgctt cagtctttca
     9901 gcatccgtct actcaatttt ttcatagtca ggtcttgcag gaattggttt tcccttgtga
     9961 aaatcagggt ttgtcaagag aagaaatcga gaatcgcctg gcttgggtta tggaattatt
    10021 tggtttggct tctcttagcc agcgaacgat ttccagtcta tcaggtggtc agcaacaacg
    10081 tctagccttg gccgttgcaa ctatgcaagg gacagatgtc ttggttttag atgagccgac
    10141 tgccaaccta gatcaggaag ggattgtgat tgtagaggac atcttgaaaa ctgtaaaaag
    10201 ccaaggcaag accattatta ttgccgagca tagactgtct tatctcagtc aattggcaga
    10261 tcgctattta tattttcaag atgggcaagt ggtgacggat tatctagcag atgagttttt
    10321 aagtcggaca gaagaatgcc gtcaggatat gggactgcgt tgttatgact cggagcctta
    10381 tgggcgggca atagcggagc tggcagacca gtttgttaat gataaagagg ggttacttgt
    10441 tgaaaattta tcggtaagtc agaaagagaa tactctctac gagattgaaa aactctgctt
    10501 ggcaccagga caggtggtgg gtttggttgg agcgaatggt tctggaaaaa caagccttgc
    10561 tcgttatctg gtcggtttag cggaagataa gaagagtagg atttcttggc aaggtcaaac
    10621 cttatctagt cgccagagat tggaaaaaac agcctttgtt atgcaggatg ttcgactcca
    10681 actatttgcg gaaagtgttg agcgagaact tactcttgga aggaaaaata gagctgtcga
    10741 tgaacatttg gtggctcgtt ttggtctatc ggatttgttg gagagacatc cggtcagttt
    10801 atcgggtggt gaacaacagc gcgtgatgat agtagctagc ttactggcag ataaggaaat
    10861 tttcattttt gatgaaccga cgagcggctt ggatttgaga cgaatgcaac aagttgcttc
    10921 cgctttagta gacttaaaaa tgaagaataa gttggttttg ttaatttctc acgatgaaga
    10981 gctattgaat ctggtttgtg ataaaatagt agatattaaa cagttgaaat agtgattatg
    11041 aacaaacaaa cctataaaga aattttaacc attgcctttc cagccatggg ggaaaacctt
    11101 ctccagatgt taatgggggt agtagactct tatctagtag ccagtattgg cattgtagct
    11161 ttgtctggag tttcccttgc taataatatt ttagccgtct atcaggcggt ttttattgcc
    11221 ctagcagtag cggtgtcttc tcgtttggct caggctttgg gtgaaggggg ttcagaaggc
    11281 attggaggaa ctgctagtga aagtgtcaag tttacagttt ttatcggtct ccttttagga
    11341 attttttcag ttctggcagg tccaatagta cttactagct tgggggcaga gtcagaagtg
    11401 gtacaggctg ggggtcttta tttgatattg gttggtgggg gagcaccttt tttgggactc
    11461 atgacaagtt tgagtgcaat cttacgaacc ttgggggaac cacgttttcc tatgtatatc
    11521 agtctgctct caaacgttct aaatgcacta ttttcagcat ttgcagtctt tgtgcttcat
    11581 gcaggtgtag ctggagttgc gattggcacg gtattatcgc ggttgattgg ttgtagcctg
    11641 ctttggtctc gcttaccaat ttctttaaaa ccatggacct ggtcctttga taaagaactg
    11701 cttagacttg ccctgccagc aactggtgaa cggttgatga tgcgggtggg agatgtggta
    11761 gtcgtggcgt tgattaccag cttaggaaca gcgacggtag ctggaaatgc gattggagaa
    11821 accctgacgc agtttaacta tatgccggct ttagggattg ctaccgcaac aatcatcctt
    11881 acagcgaaac acagacagga taaggctatg gttcgacata tttttcgaac aagctttggc
    11941 ctttctttgc tgtttatgtt tttggtggct ggtgtgactt attttgcggg gtctttccta
    12001 atcgaccttt atactaagga tattcaagca gcacaagcta gtcaaacagt attattttat
    12061 gccatgttgg gagttccctt tacagctggc actcttatta tgacagctct ttggcaaggt
    12121 ttgggaaatg ctagattacc cttttatgcc acaactatcg gtatgtggct agtgcggatt
    12181 ggcatagctt atttacttgt aacatttttt aaaatcggtt tgtcagccat ttggattgca
    12241 acgattttag ataatgcctt ccgatcaggg gtgctatttt ttcagtatag gtattcaaaa
    12301 caagaatcaa tttaagataa ggctaagaaa attttcagtt tcttttaagt ttgtagctat
    12361 atactatatt caagctagaa atagcgaaca actttctttt tcatataatc tcctagagaa
    12421 cagtcggccg cggtcggctg ttttcgtgtg ttctattctt atgtaaaaat ggtataatag
    12481 tagtgattgt gtaaggagaa aagtatgtcg gtagtaggaa aagcaaatgg aaaaatcatt
    12541 ttgatgggag agcatgcggt ggtctatggg cacccagcaa ttgctatgcc tttttctgct
    12601 gttgaaatta ttgctcaggt aactgctcaa ggggaagcgc tgactgttgc ttgtgacttc
    12661 tataaaggct tagttcacaa gatgccaaaa atctgggaaa gcctcaagca tgccatccgt
    12721 ttctcgctct atcgtatcgg agcgccgaca gacccagcta ttcatatcga gattagttcc
    12781 accattcctg ccgagcgtgg catgggctcc agtgcagccg tggcagttgc agtagcacgc
    12841 gccctctttg cctattatga aaaagagctg accgacagcg aactctggga catcgtccag
    12901 tcttcggaaa aaattgctca cggcaatccc tcgggtattg atgcggcgac caccagcggc
    12961 aagtcccccg tcttctttat caagcaccag cccatcgaac cttttgagct gaaactccat
    13021 gcccatttgg tagtggctga cacaggtgtg acgggaaata ccttagaagc catttcagac
    13081 gtggcagatt tgttggagaa aaagccagag gctatcaagc tagtagaaga actggggaac
    13141 ttgacccgac aggccaagga agatttagcc acagaccagg cagagcttct aggcagcaga
    13201 atgaaccaag ctcatgccct cctgcaaaaa ttaggcgtgt ctgatcctag cctagataag
    13261 ctagtcagcc ttgcccaaga aaatggagcc ctcggagcca aattaactgg tggcggacga
    13321 ggcggttgca tgattgccct ggcaagaaca gctcaggatg cccaaaaact tgcacacatc
    13381 cttgaccaag caggcgcccg ccaaacctgg atacagtact taggagaaac caatgactaa
    13441 acaaataggc atagcccgtg cccataccaa tattgccttg attaaatact ggggaaaacg
    13501 cgataaggaa ttattcctac ctatgaattc cagtttatcc ctgacccttg acgcatttta
    13561 tacggatacc aaggtcgttt ttgacccaga attaactgct gatgagttct atctcaatgg
    13621 gattttacaa aaagaaaaag aaattttaaa aatttctcga tttttggatt tattttgcga
    13681 atatataggt gaaagggcat ttgcccgagt ggaaagtcta aattttgttc cgactgcagc
    13741 tggtttggca agctcagcat cagccttcgc agcgcttgcg cttgcaaccg caactgcctt
    13801 ggatttagat ttgtcaccag ccaccctatc aacccttgct cgcaggggtt ctggctctag
    13861 tacccgtagc ctattcggtg gatttgttga gtggggcatg ggaactggtt cggaagattc
    13921 gatggctcat cccattgatg atgcggattg ggatatcggc atggtcgtct tggcggtcaa
    13981 taccggaccg aaaaagattg ctagtcgaga gggaatggac cacacagttg ccacctcacc
    14041 attttacaca gcctgggtag aaaccgctaa gcaagacttg gtggacatca aggcagctat
    14101 tgccagccgt gattttgaaa aacttggtca gattacagag cacaatggca tgaaaatgca
    14161 tgcaacaacg ctctctgcca atccaccctt tacctattgg tcagccgata gcctagtggc
    14221 tcaagaggca gtccgtcagg ttcgtgaagc aactggctta tcagcctaca tgaccatgga
    14281 tgcaggacca aatgtcaagg tcctctgtcg agcaagtcag atggatgagc tagtagctgg
    14341 attggccaaa gtcttcccaa gagagaaaat catcaccagc aagcctggac ctgctgctta
    14401 tgttctcagt gagaaggatt ggcaggcatc acaaacagca tttgaaaagg gaatctagca
    14461 tgaaagtgca agtaaagata ccaggaaaac tctttctggc aggggaatat gcagttgttg
    14521 aagctggcta tcctgcggtg attgcggcgg ttggccagta cctaaccgtc accattgaaa
    14581 caagtgacca aggcagtctt cattctagtc aaaaggcaga cctttatctg acctgggagc
    14641 gtaaggaagg tgccgttcgt attcaaggta gccatcccta tgccttgatt gaatcagcta
    14701 tgcaggtgac agaagcctat ctgacggcca agggctatgc ttgtcatgga acctatagcc
    14761 tatctgtaca gtccgaccta gatgaccaag cctctggtgc caagtacggt ctggggtctt
    14821 caggagcagt aacggttgcg acggtcaagg ccctgttgac ctattacggt catcaagcgg
    14881 atgccctttt gacctacaag ctagcagctc tgacccagtc caagctaggc atgacaggtt
    14941 cctttggaga tttggcggct tccagttttg gcggcttgat agcctatcat tccctggacc
    15001 gttcttggct tttagggaaa atggcagagc tgtctctgct ggatgtggtg gaaagtgatt
    15061 ggcaaagttt gtctatcagc cctatccagt taccccaagg tctagacctc ttggttggtt
    15121 ggacagggtc ggcggcttca acggatagtc tagtttccca gatggaaagc caaaaaagtc
    15181 agacagaaaa agagcaaatt catagccagt ttttagccga ctccaagact tgtgtagagc
    15241 agttgatagt ggcctgtcag acaaatgatt cagtatcagc tagacaggcc ttgtcagcta
    15301 atcgcaagct cttacaggac tttgcgagag gaatgggctt ggtcattgaa acgcctcaac
    15361 tgagtcaact ctgtgatctg gcccaaactt atggagcggt ggccaaatca tctggtgctg
    15421 gcggaggtga ctgcggtatt tgcttggtag acagtaagga acaaaaagca gcgatagaga
    15481 cggcttggca agaagccggt atttttccac tcaccctaaa catcgcaagt agagaataag
    15541 gagaacccta tgttttatct aggagaattt ggtttagatc gcaaggatca acacgttggc
    15601 ttggccaatc agcaatatag tgccacgccg gccaaggact ttacagaaac tctgtttgtc
    15661 catcattccc tgccgcagac caaggtggat gaagtggata tttcgaccag tgtagctggt
    15721 ttggactttg cctttccttt cttcatcaat gccatgactg gtggaagcaa gaagacccgg
    15781 gaaatcaacc gtctgttggg aattatgggg cattttggca agattgccct ggcttctggt
    15841 tcggtcagtg cggcaatcaa ggatccgtct gttgcggaaa ccttctctgt tatgcgtcgg
    15901 gaaaatcctt acgggataat ctttgccaac ctaggtgccc atcatagtgt ggaaaatgcc
    15961 aagcgggcgg tggatttgtt ggaggccaat gccattcaga tccatgtcaa tgctcctcag
    16021 gagattgtca tgccggaggg ggaccgtgat ttcactatgt ggttgaagaa tattgaaact
    16081 ctggtgcggg agatggaagt gcctgtcatt gtcaaggaag ttggttttgg catgagccgt
    16141 gaaacagtag cccagctggc ttctgccggc gtgcaaacaa ttgatgtatc tggtactggg
    16201 ggaacggatt tcgccaagat tgaaaatgcc cgtcggacct tcaatgacta tgcctattta
    16261 gaaggttggg gccagtctac cgtgacttcc ttggtggaag ctatgtctgt ttctgaagaa
    16321 gtttgcccaa gcctgattgc ttctggtggc attaaaacac cgctagatat tgtcaaatca
    16381 ttggctttag gtgcagacct tgtcggtatg tccaatcatt tccttcaata tgtcaaggat
    16441 ggaaaagggc atcgttttga cgacggtttg caggctatta aggtctatca atggcagatt
    16501 gctgaaatca tgaccatgct gggtgctaag aatattgcgg aactccggca gaaagatctg
    16561 gtcttggcac caaatgtcca gaactggtgt gaggcgcgtg ggattgattg gaaagcctat
    16621 gcccgtcggt cagcgaatgt gagttaaaga gagatagatt gatgtcttca gttctcaaca
    16681 atgtagaaaa ataaaaaagc caggtccatt ttggaacttg gcttttgtca tggagtggtt
    16741 tctaggttgc tgttaactgg cctgcttgta actggtacat acggtggtag tgacccttga
    16801 gggctagaag ttcttcatga ttgcctgact cgatgatctt tcccttatcc aagacataaa
    16861 tacagtcggc atcctgaatg gtcgataggc ggtgggcgat ggcaatggtt gtccgccctt
    16921 ttcgcatttt ctcaagagaa gtctggactg tcttctccgt ctcagaatcg atattggcgg
    16981 tagcctcgtc taaaatgaga atcttaggct ggctagccat ggtgcgtgca aaggccagca
    17041 gttgccgttg tcctgtcgaa aaggcggagc cccgctcggt gaccaagtgg tcgtatttct
    17101 caggaagttt ttcgatgaag ggagcagcgt ccacaaatcg agccgcttcc tcaatctcct
    17161 cctgagaaat atcctgatac atctggatat tggatgcaat ggttccgtga aatagaaagg
    17221 gatcttgcag gactaggcca atcgcggacc gcaattcttc ctgcgaaaag ctacgaatat
    17281 cctgaccgtc aatcaaaatc cgtccagatt ggaattcata gaaacgcata aagacattga
    17341 tgatagaaga tttgcctgat cctgtagcac ccacaaaggc gatggtctgc ccctgtctca
    17401 cttcaaagga aaccttgtcc agaatttgcc gcttgccgtc ataggaaaag taaacatcct
    17461 caaagacaat atgccccttg tcaatcttgg cccctcggtc cagctgtagt ggctcctcga
    17521 tggtctggtc catgagcgta aagacccgtc cggcagatac catagaggtt tggagggtgg
    17581 aaaaatgctg cgtgacatcc agcaagggat cgaaaagacg attgacatac tggatgaaag
    17641 catagataag accagcagaa attccagcct gtgaccagtc caaaccaaaa taggtcatga
    17701 gtagggcata ggccaaaatc ttaacaagtg acagggcagg gcggagaaag agactgtcca
    17761 aggccatgga acgactggca tagtccagat gttcctggtt gatagcctca aactcttcct
    17821 ttagcctctc ctcttgagaa aaggcctgga taatccaaat cccctcgatg ctctctgcca
    17881 gtttgctgtt gatggcactc aacagacttc tagtcttggc cacaatggga gctgaccgct
    17941 tccgatactg atcaaccagg atgaaaatca cgggcaggaa gaggacaatc agactggtca
    18001 atttccaatc cagagcaaac atggtcgaaa gagtcgtgac gataataaag agagctgaga
    18061 taaaactgga taaaatccct gaaaacatct ctgaaatact ctccgtatca ttggtgatgc
    18121 gagagacaat ggaaccacta ggagtctggt cgaagtaagc cattcccagc ttttccattc
    18181 tcccaaaggc atcccggcga atatctctga caatgctgta ggaaacttta gcaaaccaga
    18241 gatttccaaa atattgaagt accatttgaa gcagatagag ggcgaagtag gcagctagaa
    18301 tggccacagc agtctcagaa atagtagaaa tgtagtggtc gataaaataa gaggctagaa
    18361 ggggaattag actgcggacc acggtagtca gtagcaaaaa gctcaaggca aggactgtca
    18421 gcagtcgata ggctttgaga taggacaaga gtcgcaaaaa aacactagct tgcttggttt
    18481 tagagagcat cactttcctc cttttcgagt tgctgcatca tataggtatc gtagtaccag
    18541 cctttttcat ctagtaattc ttggtgacga cctcgttcta cgatttttcc atcttcaagg
    18601 accagaatca aatcggcatg gacaatagct gacaggcgat gggcggtgat aatggtggtt
    18661 ttgtcaaggc gttcttgctt gatggtttcg agaatagcgt gttctgtttt agcatccacc
    18721 gctgagagcg agtcatccaa gagcaggata tctggattga gaatcatggc acgggccata
    18781 gccaaccgtt gtttttgtcc gccagaaagg gaaatcccct tttcgccgac catggtttca
    18841 aagcggtcgg gcatatcctg aatatcctca tagacatgga cagcccgagc ggcctcttct
    18901 acctgattta gagataaatc gggattgccg aagcggatgt tttcagtaat gctggtcgca
    18961 aagaggaact ggtcctgggg tacatagcca attaagcgtc gcaggtcagc tagcttgtag
    19021 ttcttgatat tttcttgatt gagcaagatc tgtccattta tcacatcgta ttctcgcatc
    19081 aggagcttga gcaggcttgt tttcccagaa cctgttagcc ccacaagacc aattgtctgc
    19141 ccttttttga tctgaaactg gatgtcttgg aggactggta tgttatcata ggcaaattcg
    19201 ctaatctcat agacaagctc tccattgctt ggtgcaggca gcggttggtc tgtttcaatg
    19261 acctctgagg aaatgctgag aagggtctga atccgattgt aagatacatc accacgctgg
    19321 ctaatattga ccaaaaaacc aatcgccata agaggccaga cgaggagatc taaataggtc
    19381 atgaaagtta ctagttggcc cagactgacc tgaccttgcg agatgaagtg agagccgacc
    19441 agaagggtca gcaggtagga caggccaatg aagaagagga cggcagggtt gaacagggca
    19501 tcgtaacgca tggttttgat attctgcaag aaggctgctt ggttgacttc ctgaaaagcc
    19561 gccgtttctt gttcttggta gccaaaggat ttagtaacct ttataccaga aacagcttcc
    19621 tggaccttgt tgttaagctc tgaaaaggct gcctgtgaag ccttgaaatt ttcatgagtg
    19681 cgacggccta aaaaattagt ggttagagtc atgaagggta gggggaggat tgcaaccaag
    19741 gtcatctgcc aggaaatgct caaactcatc gtaattaggg taaccaaggc tgtgaccgtt
    19801 gcatcaacaa aagacatgac gccaccacct gctagtcggg tcagggcatt gatatcattg
    19861 gttgcgtggg ccattaaatc cccagtccga tgttgctgaa aaaaggatgg agataggtgc
    19921 ataaagtggt caaacagccg agccctcatg atttttccta gacgataaga tgttgccagg
    19981 atgttcattc gccaaagata gcggaggccg tacatggcca aggctgacaa gatgagccca
    20041 gctaccccga gtagcaagcg atgctcagtc aactgtccgc tggcaatctg gtcaatcaac
    20101 tgccccatga tagaagcggg aaggagattg aggaggctga ccaaacagag tgataaaatc
    20161 ccaatcagat aggccttttt ctcaagggaa aagaaccacc acaattgctt gataatcttc
    20221 ataaatgtcc tttctgaaca aaagaaaggt tggtagcttg tcgcaaccaa caaataatag
    20281 aattcggtga cactagtgta tcacagactg gtagaaatag aaagtttgta acttaaaaat
    20341 taggcaactc tagccgtagc cgaatagaag aaacagttgg agttgtaaac acgtacgata
    20401 caggtagaaa tcaaaagatt tttacctttt tctgtc
//
LOCUS       DBNFCO010000036        20339 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.036, whole genome shotgun sequence.
ACCESSION   DBNFCO010000036 DBNFCO010000000
VERSION     DBNFCO010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 20339)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20339)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20339
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.036"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(<1..506)
                     /locus_tag="AC1PIV_001076"
     CDS             complement(<1..506)
                     /locus_tag="AC1PIV_001076"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HIP6612107.1"
                     /translation="MPYDIPESWEWVRLGAIVTAKGGKRIPKGYNLQEEDNGHPYLRV
                     TDMKDGTIKPTNIKFAPDNVYTIIRNYTISSTDIYVTIAGTIGDVGIVPENFNNALLT
                     ENALKLMLTESINKMFLAHLLKSPLVQKQFKEVYNQVAQPKLSIRSTNSTIIPLPPLA
                     EQKRIVAQ"
     gene            707..1381
                     /gene="rpiA"
                     /locus_tag="AC1PIV_001077"
     CDS             707..1381
                     /gene="rpiA"
                     /locus_tag="AC1PIV_001077"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HIP6612108.1"
                     /translation="MINLKEQVGIKAAEFVTDGMIVGLGTGSTAYYFVQEIGRRVAEE
                     GLQITGVTTSHATAEHAASLGIPLKNIDEVEYVDLTVDGADEVDGDFNGIKGGGAALL
                     MEKVVAVNSKDCIWIVDESKMVQTLGAFKLPVEVVQYGAENLFRLFEKKGYRPSFRMR
                     NGKKHITDMQNFIIDLDLRRIEDTYALAEELDRTVGVVEHGLFIGLISKVIVGTPEGP
                     NIIEKK"
     gene            1710..2921
                     /locus_tag="AC1PIV_001078"
     CDS             1710..2921
                     /locus_tag="AC1PIV_001078"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008973 - phosphopentomutase activity
                     [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043094 - metabolic compound salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HIP6612109.1"
                     /translation="MPKFKRVHLVVMDSVGIGAAPDSDKFFNAGVADTESDTLGHISE
                     KAGLEVPNMTKIGLGNIPRDTALATVPAESHPTGYVTKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWDGFPEEILTKIEEFSGRKIIREANKPYSGTAVIDDFGPRQMETGELIV
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFSRT
                     ANRHDYAVSPFEATVLNKLADAGVPTYSVGKISDIFNGSGITNDMGHTKSNMHGVDVL
                     IDTLKLSDFEEGFSFTNLVDFDAVYGHRRNIEGYRDCLQEFDARIPEIIDNMREDDLL
                     LITADHGNDPSYAGTDHTREYVPLLAYSKAFKGSGVLPVGHFADISATVAENFGVDTA
                     MIGESFLSQLV"
     gene            2921..3277
                     /locus_tag="AC1PIV_001079"
     CDS             2921..3277
                     /locus_tag="AC1PIV_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018029666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HIP6612110.1"
                     /translation="MEKLTVYYNPNCSKCKKLRILLSSQDMEVKWVNYLETPLRGTEL
                     TALLEKMGSQPSAVIRLKEEERLALSEEEIFERLVKEPATLNRPIIEREQTAFLCRPL
                     EIIKEKMPEYDWSDYL"
     gene            3289..4098
                     /locus_tag="AC1PIV_001080"
     CDS             3289..4098
                     /locus_tag="AC1PIV_001080"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HIP6612111.1"
                     /translation="MSLLAKINETKTFLEEKGLVKPEFGLILGSGLGELAQEVENAIV
                     IDYADIPNWGKSTVVGHAGKLVYGDLAGRKVLALQGRFHFYEGNPMEVVTFPVRVMKA
                     LGCEGVIVTNAAGGIGYGPGTLMAITDHINMTGQNPLIGENLEEFGPRFPDMSNAYTK
                     EYREKAHAVAEKLGIKLDDGVYLGVTGPTYETPAEILAFKTMGAHAVGMSTVPEVIVA
                     AHSGMKVLGISAITNFAAGFQSELNHEEVVEVTEQIKGNFKGLVKAILAEL"
     gene            4131..4844
                     /gene="deoD"
                     /locus_tag="AC1PIV_001081"
     CDS             4131..4844
                     /gene="deoD"
                     /locus_tag="AC1PIV_001081"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HIP6612112.1"
                     /translation="MSIHISAKPGEIADKILLPGDPLRAKFIAENFLEDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGIPSISIYAHELINEYGVKKLIRVGTAGSLNEDVHVRE
                     LVLAQAAATNSRMINIDWPEYDLPQIADFDLLDKAYHIAKELNMTTHVGNVLSSDSFY
                     SPKLFSRNLELGQLGVKAVEMEAAALYYLGAKFGVQTLAIMTISDSLVNPEEDTTAEE
                     RQNTFTDMMKVGLETLIAE"
     gene            5019..7286
                     /gene="glgP"
                     /locus_tag="AC1PIV_001082"
     CDS             5019..7286
                     /gene="glgP"
                     /locus_tag="AC1PIV_001082"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004645 - 1,4-alpha-oligoglucan
                     phosphorylase activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HIP6612113.1"
                     /translation="MINLQNFVQSMYAKRIEDCTDQELYYALLAFAKQQSEAKYTNDQ
                     KKKVYYISAEFLIGKLLSNNLINLGLYDEVKSQLVAAGKDLIAIEDMELEPSLGNGGL
                     GRLAACFLDSIASLGLNGDGVGLNYHFGLFRQLFEYHQQSAVPNEWITPRSWLTESPI
                     SYQVPFANFTLTSKLYDIDVPGYKMERKNRLRLFDLGSVDDNIIYDGIEFDKEDIFRN
                     LTLFLYPDDSTDEGKVLRIFQQYFMVSNAAQLLIDEAVAKGSNLHDLPDYAVVQINDT
                     HPSLVIPELIRLLELRGISFDEAVEIVKKMTAYTNHTILSEALEKWPLDFLNYVVPHL
                     VPFIVELDRRAKEVKDDPAVNIIDEHGRVHMAHMDIHYGYSINGVAALHTEILKTSEL
                     KAFYELYPEKFNNKTNGITFRRWLMHANPSLASYLDGLLGHGYHHDASELEKLLDYKN
                     DKELKSWLEKTKQHNKRKLQRHIAKTQGVHVNPESIFDVQIKRMHEYKRQQMNVLYVI
                     HKYLDIKAGNIPTRPLTVFFGGKAAPAYTTAQDIIHLILVLSQVIKNDPDVAPHLQLV
                     MIENYNVTEASYIIPAADISEQISLASKEASGTGNMKFMLNGALTIGTDDGANVEIHE
                     LVGDENIYIFGQDSQTVIEHYANGTYHPYSFYEREAIRPLIDFITSDTIRHAGGIDER
                     LWRLQDNLKHNDHFMTLLDLEDYISTKEQMLADYEDRDSWLEKVIVNIAKAGFFSSDR
                     TIQQYNEDIWHLEVK"
     gene            complement(7421..7657)
                     /locus_tag="AC1PIV_001083"
     CDS             complement(7421..7657)
                     /locus_tag="AC1PIV_001083"
                     /inference="COORDINATES: protein motif:HMM:NF016763.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HIP6612114.1"
                     /translation="MVFNLLLFLPLGLLFSFSWKKLSLFVGAILLVEACQFFFSLGFF
                     DLGDILLNTSGFALGNLLGKSAIAQSFKNRIQKK"
     gene            8112..9239
                     /gene="hemW"
                     /locus_tag="AC1PIV_001084"
     CDS             8112..9239
                     /gene="hemW"
                     /locus_tag="AC1PIV_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HIP6612115.1"
                     /translation="MKKRPTSAYIHIPFCTQICYYCDFSKVFIKNQPVDDYLVALMEE
                     VKFYDLPALKTLYIGGGTPSALSAEQLDYLLTNLEDLLDLSQLEEFTIEANPGDLTAD
                     KIAVLKKSKCNRVSLGVQTFDDRMLKKIGRSHNQAQIYETIAALKEAGFHNISIDLIY
                     ALPGQTMEQVVDNVAKALELDIPHMSLYSLILENHTVFMNRQRRGNLHLPNEDVESDM
                     FDYILQELEKNGFEHYEISNFTKPGFESHHNLMYWDNSEYYGLGAGASGYIDGMRYRN
                     RAPIQHYLKSIREKGHSRLHEEFLSKTEQMEEEMFLGLRKKTGVSIERFEKKFGISFE
                     DRYGQVVRDLKNEGLLQEEDCWLRMTKKGLFLGDTVAERFI"
     gene            9470..10210
                     /locus_tag="AC1PIV_001085"
     CDS             9470..10210
                     /locus_tag="AC1PIV_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP thioesterase domain-containing protein"
                     /protein_id="HIP6612116.1"
                     /translation="MGLTYQEEFTIPFDMVDVKQEIKLPDFISYCLGVSGRQSEELGR
                     SDLYVFQEFGLIWVVTDYELTIQRLPKYNETITIKTEAVAYNKFFCHRMFYIYDAAGN
                     LLLDILCYFVLIDFETRKVAPVPEDLIAPYQSEQVKKLPRAPKYQLLENPSVQEFPVR
                     YFDLDMNGHVNNGKYLEWMYEALGYDFLLCHVPKKIQLKYLKEVEATSLVSSRMVAEA
                     GGSQHEIVVDGHIHAQAVIEWRERHVAG"
     gene            10197..10814
                     /locus_tag="AC1PIV_001086"
     CDS             10197..10814
                     /locus_tag="AC1PIV_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase N-terminal domain-containing
                     protein"
                     /protein_id="HIP6612117.1"
                     /translation="MSQDKWLEWAVRLQALAQTGLAYGKDVYDMERFEEIRQIAAEML
                     VEPSGQPLEVVKDLFCNETGYQTPKLDTRAAIFQEDKILLVQENDGLWSLPGGWCDVD
                     QSVKDNVVKEVKEEAGLDVEAQRVVAILDKHKNNPAKSAHRVTKVFILCRLLGGEFQP
                     NSETVASGFFSLDDLPPLYLGKNTAEQLALCLEASRSEHWETRFD"
     gene            10824..11597
                     /locus_tag="AC1PIV_001087"
     CDS             10824..11597
                     /locus_tag="AC1PIV_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HIP6612118.1"
                     /translation="MTYTGYLIDLDGTIYEGKKRIPAGERFIHRLQECQIPYLFVTNN
                     TTRRPEMVQAMLAENFNIETPLETIYTASLATVDYMNDLGKEKTVYVIGEDGLKSAIF
                     EAGYVEDTENPAYVVVGLDTQLTYEKLTIATLAIQKGATFIGTNPDLNIPTERGHLPG
                     AGSLIALLKAATRVEPTFIGKPEAIIMDKALEILGTERSQTVMVGDNYLTDIRAGIDN
                     GFPTLLVLTGFTKPEEVADLPLAPTHVLNSLDEWSFDEN"
     gene            11587..12216
                     /locus_tag="AC1PIV_001088"
     CDS             11587..12216
                     /locus_tag="AC1PIV_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HIP6612119.1"
                     /translation="MRTKLQIIGTILFVLSAAVLGTIYLAWLVYPLEISFLGLEKVVY
                     MKVADISYNFNILMNYLTNPFASVLDMPNFSSSADGLKHFADVKHLFHLTQGIFILTL
                     PAFVLFVKNILLKGYGDLVKKVIFWTMLTPMIIGLLGVLVGFDQFFALFHTVLFPGDS
                     TWLFDPAKDPVIYILPQEFFLHCFVLFFVLYEFFFWTILAWTGKKNRIG"
     gene            12315..12491
                     /gene="rpsU"
                     /locus_tag="AC1PIV_001089"
     CDS             12315..12491
                     /gene="rpsU"
                     /locus_tag="AC1PIV_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HIP6612120.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEAARKRKKF"
     gene            12595..13608
                     /gene="galE"
                     /locus_tag="AC1PIV_001090"
     CDS             12595..13608
                     /gene="galE"
                     /locus_tag="AC1PIV_001090"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HIP6612121.1"
                     /translation="MSILVTGGAGYIGSHTVVELLKLGKEVVIVDNLSNSSILVLDRI
                     ETITGKRPTFYELDVADKEALRQVFENENIEAAIHFAGYKAVGESVAKPIMYYENNIM
                     STLALVEVMTEFSVKKIVFSSSATVYGLNNPSPLVETMPTSATNPYGYTKVMLEQILR
                     DVEVADKEWSIALLRYFNPIGAHESGLIGEDPAGIPNNLMPFIAQVAVGKREELSVFG
                     NDYDTIDGTGVRDYIHVIDLALGHIKALEKISTTTGVYTYNLGSGQGTSVLELVKAFE
                     KVNGVPVHYKLVDRRPGDVATCYANADKAWKELNWKTEKTIEDMCQDTWNWQSKNPNG
                     YEG"
     gene            complement(13699..14064)
                     /gene="mscL"
                     /locus_tag="AC1PIV_001091"
     CDS             complement(13699..14064)
                     /gene="mscL"
                     /locus_tag="AC1PIV_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HIP6612122.1"
                     /translation="MLKDLKAFLFRGNIVDLAVAVVIGGAFGAIIKSFVNDIITPLIL
                     NPALKAANVQNIADLAWNGVKYGSFLSAVINFLIIGTSMFFVVKAAEKAMPKKVEEKA
                     PAGPTQEELLAEIRDLLKK"
     gene            14246..16036
                     /gene="dnaG"
                     /locus_tag="AC1PIV_001092"
     CDS             14246..16036
                     /gene="dnaG"
                     /locus_tag="AC1PIV_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed RNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HIP6612123.1"
                     /translation="MLSKDKITEIKQALNIVDVIGETVALTKAGRNYVGLCPFHGEKT
                     PSFNVIEDKQFYHCFGCGKSGDVFKFVEEVRGVSFADAAAILAEKAGFQIDVTPSYHQ
                     EEKRVSPHQVLYDIHRDAAKFYHALLMTTKMGEEARAYLHQRGLTDDVIKTFQLGLAP
                     AEQNILYQKLSGQYDEESLLNSGLFNPSENNIIYDAFQARIIFPLADEYGRIVAFSGR
                     IWTEENRNNKQLAKYKNSRSTAIFNKSYELYHLDKAKAVIKKQRETYLMEGFLDVIAA
                     HRVGIDNAVASMGTALTREHVAHLAKFCKKIVLTYDGDKAGQAATMKALDELQDFQVE
                     IVSLPDNMDPDEFLQKNSEEALQQVLTKSRISDVEFLIQYLKPENPDNLQMQIEFVDK
                     IAPIIAKVSSITAQNSYIYKVADLLSDFDYNQVEQAVNAVRLNQRQERTQQVFQSQTG
                     QSYLPPVQTIARITSLIRTENHLLYRMVEHPYILNEFRLREDFYFATPELQAIYDMLK
                     KSGEITSFELSQLNDSAQQAWYRMQEERLPDEVSPHEIEELEIRRDKELLKKENQHLA
                     RKIREHSHVGNADIALDELQKLLDRRRQME"
     gene            16039..17157
                     /gene="rpoD"
                     /locus_tag="AC1PIV_001093"
     CDS             16039..17157
                     /gene="rpoD"
                     /locus_tag="AC1PIV_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009910370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HIP6612124.1"
                     /translation="MTNKKDKKTEVTTFDVQVAEFIRNHKKQGSATDDEINDQLVIPF
                     TLDADGIDDLLQRIQDAGISIVDKEGNPSARAMQVEEEPELSDEELLGSTSAKVNDPV
                     RMYLKEIGVVPLLTNEEEQELALAVEAGDPEAKQRLAEANLRLVVSIAKRYVGRGMQF
                     LDLIQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVET
                     INKLVREQRNLLQELGQDPTPEQIAERMDMTPEKVREILKIAQEPVSLETPIGEEDDS
                     HLGDFIEDEVIENPVDYTTRVVLREQLDEVLDTLTDREENVLRLRFGLDDGKMRTLED
                     VGKVFNVTRERIRQIEAKALRKLRHPSRSKPLRDFIED"
     gene            17326..17649
                     /locus_tag="AC1PIV_001094"
     CDS             17326..17649
                     /locus_tag="AC1PIV_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HIP6612125.1"
                     /translation="MTYTEDQIKDIQERIFHALEDVIDPELGIDIINLGLIYEIRFIE
                     GKAEIDMTLTTMGCPLADLITDQIHDVLKDVPEVTEVDVRLVWSPAWTVQKMSRYARI
                     ALGIK"
     gene            17830..17987
                     /locus_tag="AC1PIV_001095"
                     /pseudo
     CDS             17830..17987
                     /locus_tag="AC1PIV_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775157.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(18074..19204)
                     /locus_tag="AC1PIV_001096"
                     /pseudo
     CDS             complement(18074..19204)
                     /locus_tag="AC1PIV_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564846.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISAs1 family transposase"
     gene            19300..19623
                     /gene="tnpA"
                     /locus_tag="AC1PIV_001097"
                     /pseudo
     CDS             19300..19623
                     /gene="tnpA"
                     /locus_tag="AC1PIV_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679713.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(19763..>20339)
                     /locus_tag="AC1PIV_001098"
     CDS             complement(19763..>20339)
                     /locus_tag="AC1PIV_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HIP6612126.1"
                     /translation="KTIQVLSILTLIGTAIFLFWLYKIGILNDQNVLSDLIKSQGALG
                     SLSFLAIQIIQVVFPIIPGGVTTVVGFLVFHFWWGFFLNYLGISIGSIILFWLARRYG
                     KKFCLLFMSEDTFYKYESKIDNKRSYEIFFILCMLSPISPADIVVMITGLTSMSYRKF
                     IMITLLCRPFSVVAYSFFWIYGSQWLQQLLG"
BASE COUNT         6133 a         3914 c         4461 g         5831 t
ORIGIN      
        1 atttgggcaa caattcgttt ttgttcggct aggggtggga gagggataat tgttgagttt
       61 gtgctacgaa tggacagttt aggctgagca acttgattat aaacttcttt gaattgtttt
      121 tgaactaatg gagacttcaa gagatgagcc aaaaacattt tattgatact ttctgtcagc
      181 atcagtttaa gggcattttc ggttaataga gcattattaa aattttccgg aactattcca
      241 acatcaccaa tagttccagc tatcgtgaca tatatatcag tactcgaaat agtgtaattt
      301 cttattattg tatatacatt atctggagca aattttatat tagttggttt tatcgtacca
      361 tctttcatat ctgtaactcg aagatatgga tgaccattat cttcttcttg cagattgtac
      421 cctttaggta ttctttttcc acctttagca gtaacaatag cacccaacct cacccactcc
      481 cagctctctg gtatatcata aggcacttca atttcttgga ctgtcccatc agctaacttc
      541 tcataaggtt tcctacgtcc ctaagttagt agcaaatata tttgaacaaa tgaaaaaaat
      601 tttttaggat ttaagacatt attttttgaa tttctaactc actcttgtcc catctccctc
      661 tccatgctat actatatgta ttcgttttac ttcaaaggag acaaagatga taaacctaaa
      721 agagcaggtt gggattaagg cggcggaatt tgtgacggac gggatgattg ttgggctggg
      781 aactggttcg acggcatact atttcgtgca ggagattggc cgccgggttg cagaagaagg
      841 gctacagata acaggcgtaa cgacctctca tgccacggct gagcacgctg cgtcccttgg
      901 gattccccta aaaaatatcg acgaagtcga atatgtggac ttgacggtgg atggagcaga
      961 tgaggttgat ggtgacttca atgggattaa aggcggtggt gcagcgcttc tcatggagaa
     1021 agtggtagca gtcaatagca aggactgcat ctggattgtg gatgagtcta agatggttca
     1081 aaccctagga gccttcaagt tgccggtgga agtcgtgcag tacggtgcgg aaaatctttt
     1141 ccgactattt gagaaaaaag ggtatcgtcc aagttttcgt atgcgtaatg gaaaaaaaca
     1201 tatcacggat atgcagaact ttatcattga ccttgatttg cgcagaatag aagacacata
     1261 tgcattggcg gaagaattgg atcggaccgt cggtgttgta gaacacggtc tctttattgg
     1321 attgatttcc aaggtaattg ttggtacacc agaaggaccg aacatcatcg aaaagaaata
     1381 aattgaaaac gcttctcatt ttggtacaat gagaggcgtt tttatggtat aatgaaaaca
     1441 cgaacgttta gactcttcaa aaatctatcc ccttacctcg tagcagtcag atgataggta
     1501 ctgaaaaagc gatagctgaa cagcaggcag tgaagcgagt aacagtatct agttttgatg
     1561 gttaagaagt ttgatgccga gagctttgac tgtataagta ttgcacccca ttaaaatgtt
     1621 taggtgtggt gatgataatt tccagtctag caacttggtt ggacgctgat tttggttgaa
     1681 tctaactata tcaaataaag gagacaatta tgcctaaatt taaacgtgtt cacttggtag
     1741 ttatggactc tgtcggaatc ggcgcagcac cagactcaga taaatttttc aatgcgggtg
     1801 tagcagatac agaatctgac actctcggcc acatttctga aaaagctggg cttgaggtgc
     1861 ctaatatgac caagattggt cttggaaata tccctcgaga tacagcgctt gcgacagttc
     1921 ctgctgaaag ccatccaact ggttacgtga ccaagttgga agaagtatcg cttggtaagg
     1981 ataccatgac tggacactgg gaaattatgg gtctcaatat tactgagcca tttgatacat
     2041 tctgggatgg tttccctgaa gagattttga caaaaatcga agaattctca ggtcgtaaaa
     2101 tcatccgcga agcaaacaag ccgtattcag gtacagctgt cattgatgac tttggccctc
     2161 gccaaatgga aactggggag ttaattgtct atacctccgc agacccagtc cttcagattg
     2221 cagcccacga agacattatt ccgctggatg aattgtatcg tatctgtgaa tacgctcgct
     2281 ccattaccct tgaacgccca gctcttcttg gtcggattat tgcccgtcca tacgttggtg
     2341 agccaggcaa tttctcacga actgccaacc gtcacgacta tgcagtatca ccttttgagg
     2401 caacagtact caacaaactg gcagatgcgg gtgtaccaac ttactcagtt ggtaaaatca
     2461 gtgatatttt caatggttca ggtattacaa atgatatggg tcacaccaag tccaacatgc
     2521 acggtgtcga tgtgttgatt gatactctga agttatcaga cttcgaggaa ggtttctcct
     2581 tcacaaactt agttgacttt gatgctgtgt atggtcaccg tcgcaatatc gaaggctacc
     2641 gcgattgttt gcaagagttt gatgcacgta ttccagagat tattgacaat atgcgtgaag
     2701 atgacctgct cttgattact gcagaccacg gcaatgatcc atcctatgct ggaacagatc
     2761 acacacgcga atatgtgcca ctcttagcat acagcaaggc tttcaaaggt agcggtgttt
     2821 tgccagtagg ccattttgcg gacatttcag caaccgttgc ggaaaacttc ggagtggaca
     2881 cagccatgat tggcgaaagc ttcttgtcac aattggttta atggagaagc taacggtcta
     2941 ttacaatcct aactgtagca agtgtaaaaa attaagaata ttgctgtcca gccaggatat
     3001 ggaagtcaag tgggttaatt atttggaaac accattaagg ggaactgaat tgacagctct
     3061 cttggaaaaa atgggcagtc aaccttcagc agttattcga ttgaaggaag aagaacgact
     3121 agccttgtca gaagaagaaa tctttgagcg tttagttaaa gagcctgcca ctctcaatcg
     3181 ccccattatc gagcgagagc agacagcctt cctctgtcgt ccgcttgaaa tcattaaaga
     3241 aaaaatgcca gaatatgact ggtcggatta tttataaaag gagaaaatat gagtttactt
     3301 gcaaaaatca atgaaacaaa aacgttcttg gaagaaaaag gtttggtaaa acctgaattc
     3361 ggtttgattt tgggttctgg cttgggtgaa ttggcccaag aagttgaaaa tgctattgtc
     3421 atcgactatg cagatattcc aaactggggt aaatcaacag ttgttggtca tgctggtaag
     3481 ttggtttacg gtgatttggc aggacgtaag gtcttagctc ttcaaggtcg tttccatttc
     3541 tacgaaggaa atccgatgga agtcgtgact ttcccagtcc gtgtcatgaa agctcttggt
     3601 tgtgaaggag tgattgttac taatgccgca ggtggtattg gctacggtcc aggtaccctt
     3661 atggccatta cagaccacat caacatgact ggccaaaatc cattgattgg cgaaaacttg
     3721 gaagaatttg gtccacgttt cccagatatg tccaatgcct acactaaaga ataccgtgaa
     3781 aaagcccatg ccgttgcgga aaaattgggt atcaagttgg acgatggtgt ctacctcggt
     3841 gtgacaggcc ctacctatga aacacctgct gaaatcttgg ccttcaagac catgggggcc
     3901 cacgcagtcg gtatgtcaac agtaccagaa gttatcgtgg cagctcactc aggcatgaaa
     3961 gtcttgggta tttctgctat cacaaacttt gcggctggtt tccaatctga acttaatcac
     4021 gaagaagttg tagaagtaac cgagcaaatc aagggcaact tcaagggctt ggtgaaggct
     4081 atcttggctg agttgtaagt attcgaaaat agaacaaaga ggtacattac atgtctatcc
     4141 atatttccgc aaaaccaggc gaaatcgctg ataagatttt gcttcctggt gatccgcttc
     4201 gtgctaaatt tatcgctgaa aacttccttg aagatgccgt ttgcttcaac gaagttcgca
     4261 atatgttcgg ctacacaggt acctacaagg gtcatcgtgt ctctgtcatg ggaacaggta
     4321 tgggaatacc atccatatct atctatgctc atgaattgat taacgaatat ggtgtgaaaa
     4381 aactaattcg tgtgggaaca gcaggttctt tgaatgagga tgtccatgtc cgtgaattgg
     4441 tcttggctca ggcagctgcg accaactctc gtatgatcaa tattgactgg ccagagtacg
     4501 atttgccaca aatcgctgat tttgatcttt tagataaggc ttatcatatc gccaaagaac
     4561 tcaacatgac aacgcatgtt ggcaatgttt tatcatcaga tagtttctat tctccaaaat
     4621 tgtttagtcg caacttagaa ttaggtcaac taggtgtcaa ggctgtagaa atggaagcag
     4681 ctgcacttta ttacctaggt gctaagtttg gcgttcaaac gcttgccatt atgacgattt
     4741 cagatagctt ggttaatcca gaggaagaca ccacagcaga agagcgtcaa aatactttca
     4801 cggatatgat gaaagttggt ttggaaactc tgattgcaga ataattaaga ataattctga
     4861 ttgtagtaac ctgcaatcgt ttaaaagacg aactaatttc tatttgtacg gaagttggct
     4921 tgtctttttt tataaatagg gtataattaa gaaaacgttt acaaaggtaa agcgaaacct
     4981 ttctgaatga ttacattaat atatctagga gagccctcat gattaattta caaaattttg
     5041 ttcagtctat gtatgccaaa cgcattgaag attgtacaga ccaagaactc tattacgcct
     5101 tgcttgcttt tgcaaaacag cagagtgaag ctaagtatac aaatgaccaa aagaaaaagg
     5161 tctactatat ttcagcagag ttcttaattg gtaagctctt gtctaataat ttaatcaacc
     5221 ttggtcttta tgatgaggtt aaaagccagt tggtggcagc tggtaaggat ttgattgcta
     5281 ttgaagacat ggagcttgaa ccgtctcttg gtaatggagg tttggggcgc ttggctgcct
     5341 gcttccttga ttcaattgct agtctaggtc ttaacggtga tggggtcggc ttgaattatc
     5401 actttggact gtttagacaa ttatttgaat accatcagca gtctgctgtg ccaaacgagt
     5461 ggattacacc acgttcatgg ttaacagagt caccgatttc ttatcaggtg ccatttgcta
     5521 actttacctt gacatctaag ttgtatgaca tcgatgtacc tggttataaa atggaacgca
     5581 agaatcgact tcgcttgttt gaccttggtt cagttgatga caatatcatt tatgacggaa
     5641 tagaatttga taaggaagat attttccgaa acttgaccct cttcctctat ccagatgatt
     5701 cgaccgatga aggaaaagtt ctccgcatct tccagcaata tttcatggtg tctaacgctg
     5761 cgcaactatt gattgacgaa gcggttgcta agggatcaaa cttacatgac ctacctgatt
     5821 atgccgttgt tcaaatcaac gatactcacc catcacttgt tattccagaa ttgattcgcc
     5881 ttttggagct ccgtggtatt tcgtttgatg aggcagttga aattgttaag aaaatgactg
     5941 cttataccaa ccataccatc ttgtcagagg cgctggaaaa atggccgctt gattttctga
     6001 actatgtggt tccgcacttg gtaccgttca tcgtagaatt ggatcgtcgt gccaaagaag
     6061 tgaaggatga tcctgctgtc aatatcatcg atgaacatgg ccgtgttcac atggcacaca
     6121 tggatattca ttatggttat tccatcaatg gggtggcggc acttcataca gagattttga
     6181 aaacttcaga gttgaaagct ttctatgagc tatatcctga aaaattcaat aataagacaa
     6241 atgggattac cttccgtcgt tggctcatgc atgctaatcc aagtttggca agctacctgg
     6301 acggcctact tggacatggc taccatcacg atgcaagtga gctcgaaaag ctgttggatt
     6361 acaaaaatga taaggaattg aaatcttggt tggaaaagac aaagcagcat aataaacgca
     6421 aattgcagcg ccatattgcc aagacacaag gtgttcatgt taatccagaa tccatctttg
     6481 atgtacaaat caagcgcatg cacgagtaca agcgtcagca gatgaatgtt ctttatgtta
     6541 tccataagta tctggatatt aaagcaggca acatccctac tcgcccatta acagttttct
     6601 ttggtggaaa ggctgcacct gcttacacaa ccgcacagga catcattcat ttgattttgg
     6661 tattgtcaca ggtgattaaa aatgatcctg acgtggcgcc acacttgcaa ctcgttatga
     6721 ttgaaaacta taacgtaacc gaggcaagtt atattattcc agcggcagat atttcagaac
     6781 aaatttctct tgcatccaaa gaagcttctg gtacaggtaa catgaaattc atgctcaacg
     6841 gagccttgac catcggtaca gatgatgggg ccaatgtgga aattcatgag ttggtaggtg
     6901 atgaaaatat ttatatcttt ggtcaagata gccaaacagt tatcgaacac tatgcaaatg
     6961 ggacctacca tccatattcc ttctacgaac gtgaagccat tcgcccattg attgacttta
     7021 ttacatcgga taccattcgt catgctggtg ggatcgatga gcgtctctgg cgtttgcagg
     7081 ataaccttaa gcacaatgac cacttcatga ccctgcttga tttggaagat tatatctcga
     7141 ctaaagagca gatgttagca gactacgaag atcgcgacag ctggttggaa aaagtcatcg
     7201 tcaacatcgc taaagcaggt ttcttctcgt cagaccgtac tattcaacag tacaacgaag
     7261 acatctggca tttggaagtt aagtaagcta atactcttcg aaaatcaaaa ttatccgttg
     7321 tcaagagcct agatgaactt cagttctatc gtcggcttcg tttcctaggc tacttttgat
     7381 tttcattgag tataaataaa ctaaaaatga ccttgcgggg tcattttttc tgtattctat
     7441 ttttaaaaga ttgagcgatt gcggattttc ccaaaaggtt tccaagggca aagccagaag
     7501 tgttaagcaa gatgtcgcca aggtcaaaga agcccagtga aaagaagaat tgacaggctt
     7561 caaccagtaa aatagcacct acaaagagag aaagtttttt ccaagaaaat gaaaaaagca
     7621 acccaagtgg taaaaagagt aagaggttaa aaaccaatat agtaggattg agaaataggt
     7681 cttgtgaaaa agtgctaagg agattctagt tgacacctct gacgcccatg cttttgaaaa
     7741 agagaagata gactagcaga agcccgtagc aagcgtagaa aaaccaaagt gtcagtcgcg
     7801 aaatgtgggg tttatagaca agtcgaaata gggtaaagca aaatccggtc attaacagga
     7861 ttgcggcaag tgtcggccaa aaatcaactg tcatgaaaat ggtcgtgaac tggtaaaaaa
     7921 gaaaggtcat aaagagccag cggcagaata agaatgataa gatagcgttg atgacatcat
     7981 agaatcgttc tttgttcatg atttaatccc ttttgtagat tttgtaagtt tactatatta
     8041 tatcattgtt ttgaggggga agtgatggct gtaaaaaata tttttataga cagtgtgcta
     8101 taatagttct tatgaaaaaa cgaccgacat ctgcctatat ccacattcca ttttgtaccc
     8161 agatttgtta ctactgtgac ttttccaagg tttttattaa gaaccagcct gttgatgact
     8221 atttggtagc cctcatggaa gaggtcaagt tttacgacct tccagccctc aagaccctct
     8281 acatcggagg cggaacaccg tcggctctat cggcagaaca gttggactac ctcctgacca
     8341 atctggagga cttgctggac ttgtcacagc tggaagaatt cactatcgag gccaatccag
     8401 gtgacttgac ggcggataag atagcagttc tgaaaaagtc caagtgcaat cgggtgtcgc
     8461 ttggcgttca aacatttgat gaccgtatgt tgaaaaaaat tggtcgcagc cacaatcagg
     8521 cccagattta tgaaaccatt gcggccctca aggaagcggg cttccacaac atttccattg
     8581 acctgattta tgccctgcct ggtcagacca tggagcaggt ggtggacaat gtcgccaagg
     8641 ccttggagct agatattccc cacatgagct tgtatagttt gattttggag aatcacacgg
     8701 tcttcatgaa ccgccagcgt cgcggcaatc ttcatctacc caacgaagat gtggagtccg
     8761 atatgtttga ctacattctt caggagttgg agaaaaacgg cttcgaacac tacgagattt
     8821 ccaacttcac caagcctggt tttgaaagcc accacaacct catgtactgg gacaactccg
     8881 agtattacgg attgggagca ggggcttcag gctacatcga cggcatgcgt tatcgcaacc
     8941 gtgcccccat ccagcactac ctcaagtcca tccgcgaaaa aggccattct cgcttacacg
     9001 aagaatttct cagcaagacc gagcagatgg aagaagagat gtttttaggg ctacggaaaa
     9061 aaactggcgt gtccattgag cgattcgaga aaaagtttgg tatctccttt gaagaccgct
     9121 acggtcaggt ggtcagagac ttgaaaaatg aaggactctt gcaagaagaa gactgttggc
     9181 ttcggatgac taaaaaggga ttgtttctgg gcgatacagt tgcagagcgt ttcatatagt
     9241 cattcagttt gtttttatta cttcgacgag cgaagaaact tcgtttcctt atttccaact
     9301 tcaaacactc cactggagta tttgaactca ctttgccgta ctctacgaat gttacttact
     9361 atcgtaagta cgatttccaa ccttcaatag tccactggac tattgaagct acctgcagct
     9421 gttgacgtga actgaaagac tatactttaa gactagaaag atcaacatta tgggactaac
     9481 ataccaagaa gagttcacca ttccttttga tatggtggat gtcaaacaag aaatcaaact
     9541 acctgacttt atttcctact gtcttggtgt atcaggtcgg cagtcggaag aactgggtcg
     9601 cagtgacctc tatgtttttc aggaatttgg cttgatttgg gtggtgacag attatgaact
     9661 gaccattcaa cgtttaccta agtacaatga aaccattacc attaagacag aagcggttgc
     9721 ctacaacaag tttttctgtc atcggatgtt ctatatctac gatgcagcag gcaatctttt
     9781 gttggacatt ctctgctatt ttgtcctgat tgattttgaa actcgcaagg tggcgcctgt
     9841 gccagaagat ttgattgctc cttatcagtc tgagcaggtc aagaaattgc ctcgggctcc
     9901 caagtatcag ctcttggaaa atccatctgt ccaagaattt cctgttcgct attttgactt
     9961 ggatatgaat gggcatgtca ataatggcaa gtatttggaa tggatgtatg aagcactggg
    10021 ctatgatttt ctgctctgcc atgtccctaa aaaaatacaa ctcaagtatc ttaaagaggt
    10081 agaggcaact agcttggtga gttcgcgtat ggtggcagaa gctggtggta gtcagcatga
    10141 gattgtggta gatgggcata tccatgcgca agctgtcata gaatggaggg aacgtcatgt
    10201 cgcaggataa gtggttggaa tgggccgtac gtttacaagc cttggctcag acaggcttgg
    10261 cctatggaaa agatgtttat gacatggaac gtttcgaaga aatcagacag attgcggcgg
    10321 aaatgttggt agagccatct ggacagcctt tggaagtagt gaaagacttg ttttgcaatg
    10381 aaacaggcta tcagacaccc aagctggata cccgcgcagc tattttccaa gaggataaaa
    10441 tcctactggt tcaggaaaac gatgggctct ggtccttacc aggcggttgg tgcgatgtgg
    10501 accagtctgt caaggacaat gtagtcaagg aagtaaagga agaagcgggg ctggatgtgg
    10561 aggctcaacg tgtggtggcg attttggaca aacacaagaa caatcctgcc aagtcagccc
    10621 accgcgtgac caaggtcttc attctatgtc gtctccttgg cggggagttt cagcccaatt
    10681 cggaaacagt tgccagtggc tttttcagtc tagatgactt accaccgctc taccttggga
    10741 aaaatacagc tgagcagtta gcactttgct tggaagctag tcggtctgag cattgggaaa
    10801 cacgatttga ttaaggagga aaaatgacat atacaggtta tttgattgat ttggatggta
    10861 cgatttatga agggaaaaag cggattcctg ctggtgaacg ttttattcat cgcttgcaag
    10921 aatgtcagat tccctattta tttgtgacca acaataccac ccgccgtcct gagatggtgc
    10981 aggctatgtt ggctgaaaac tttaacattg agacaccgct tgaaacaatc tatacagcca
    11041 gtctggcgac agtagattat atgaatgact tgggcaagga aaagacagtc tatgtcattg
    11101 gagaagacgg gctcaagtct gccatttttg aggcaggtta tgtggaagac acggaaaatc
    11161 cagcctatgt tgttgtcggt ttggatactc agttgaccta tgaaaaactg accattgcca
    11221 ccttggctat tcaaaaggga gcgaccttta tcggtaccaa tcctgatttg aacattccga
    11281 ctgaaagagg tcatttgcca ggagcaggct cacttattgc gcttttgaaa gctgctaccc
    11341 gagtagagcc gacctttatc ggtaagcctg aagccattat catggacaag gctctggaga
    11401 ttttaggcac agaacgcagc cagacagtta tggtaggaga taactacctg acagatattc
    11461 gtgcagggat tgacaatgga tttccaactc ttttagtcct gacaggattt accaagccag
    11521 aagaagtagc agacttaccc ctggctccaa cccatgtcct caacagccta gatgaatgga
    11581 gttttgatga gaactaagtt acagattatc ggaacgattt tatttgtctt atcggcagca
    11641 gttctaggaa ccatctacct agcttggcta gtttatccgc ttgagatttc ttttttgggg
    11701 ttggaaaaag tggtctacat gaaggtggca gatatttcct acaatttcaa tatcctgatg
    11761 aactatctaa caaatccttt tgcaagtgtt ttagacatgc caaatttttc atcctcagct
    11821 gatggtctga aacattttgc ggatgtgaaa catttattcc atctaactca gggaattttt
    11881 atcctcaccc tccctgcctt tgtgcttttt gtaaaaaaca ttctgctaaa aggttatgga
    11941 gacttggtta aaaaggtcat tttctggacc atgcttacgc caatgataat cggtttatta
    12001 ggagttcttg ttggctttga tcagtttttt gcattgtttc atacggtgct atttccagga
    12061 gattctacat ggctatttga ccctgcaaag gatcctgtca tatatatttt gccccaagag
    12121 tttttcttgc attgctttgt attatttttt gtcctttacg aattcttctt ttggacaata
    12181 ctggcgtgga caggaaaaaa gaataggata ggataagagc gtaaaattca tattttagaa
    12241 tgaaaaaaat attgacaaat gagttgaatc atagtaaaat gataaagact ttgaaattga
    12301 ggggagtgaa aaaaatgtca aaaacagtag tacgtaagaa cgaatcactt gatgatgctc
    12361 ttcgtcgttt caaacgtgcg gttactaaag ctggtactct tcaagaaaca cgcaaacgcg
    12421 aattctacga aaaaccatct gtaaaacgta aacgtaaatc agaagcagct cgcaagcgta
    12481 aaaaattcta attgaatttg aaaacggccg aaaggctgtt ttttgtttac tttttacaac
    12541 aggtaacata taatagggat atagaatttt gtccaggtga aaaggagtaa aaagatgagt
    12601 atcttagtta ctggtggtgc aggttatatt ggtagtcata cggttgtcga attgttgaag
    12661 ttggggaaag aagtggttat cgtggataat ctttcaaact caagtatttt ggttttagat
    12721 cgcattgaaa ccatcactgg caagcgccca actttctatg agttggacgt ggcagataag
    12781 gaagccttgc gccaagtttt tgaaaatgaa aacattgagg cagccattca ctttgctggc
    12841 tacaaggcag taggagaatc agtggctaag ccaattatgt actatgaaaa caatatcatg
    12901 tcaaccctag ctttggtaga agtcatgaca gaatttagtg ttaagaaaat tgtcttctcc
    12961 tcaagtgcga ctgtttatgg tctcaataat ccatcgcctt tggttgaaac tatgccaact
    13021 agcgcaacga atccgtacgg ctataccaaa gttatgttgg aacaaatctt gcgtgatgtg
    13081 gaagtagcag ataaggagtg gagtattgca ttgctccgtt atttcaatcc aatcggtgcc
    13141 catgaatctg gcttgattgg ggaagatcca gctggtattc ctaataattt gatgccgttt
    13201 attgcacagg tagcagttgg taaacgtgag gaactcagcg tttttggtaa cgattatgat
    13261 acaattgatg gtactggagt gcgtgattat atccatgtga ttgatttggc actcggtcat
    13321 atcaaggcgc ttgaaaaaat ttcaactact acaggtgtat atacttacaa tcttggttca
    13381 ggtcaaggaa caagtgtatt ggagttggtc aaagcctttg aaaaggtaaa tggcgttcca
    13441 gtacactata aacttgttga ccgtcgtcca ggtgatgtgg caacctgtta cgccaacgca
    13501 gacaaggctt ggaaagagtt aaattggaaa acagaaaaaa caattgaaga catgtgtcaa
    13561 gatacgtgga actggcaatc gaaaaatcca aatggatacg aaggataaga aaagatgtga
    13621 gtggaggctc acatcttatt tttgtaatta tggaagagaa aaacaggtat ggagacctgt
    13681 ttttcaatat attattgatt attttttcaa taaatcgcgg atttctgcaa gcaactcttc
    13741 ttgagttgga ccagcaggag ctttctcttc aactttctta ggcattgctt tctcagctgc
    13801 tttaacaaca aagaacattg aagtgccaat gattaggaag ttaataacag cgctcaagaa
    13861 actaccgtac ttcacaccat tccatgcaag gtcagcaata ttctgtacat ttgccgcttt
    13921 caaagctggg ttcaaaatca atggagtgat gatatcattt acaaatgatt tgataattgc
    13981 gccgaacgct ccgccaatta ccactgctac agcaaggtca acaatgttcc cacggaacaa
    14041 aaatgctttt aaatctttca acatatccta aatatgtcct ttcataaata ttttacttta
    14101 tctattatac ccataaaaaa atattttaca agcaatttgt tttagaaatt ttacattttc
    14161 ccatatttag tatacaatag agtatgttaa actaagggga gagtgttcac tttttaaatt
    14221 agctagtatg atatgaggag ggaatgtgct ttcaaaggat aaaattactg aaataaaaca
    14281 agctctcaat atcgttgatg ttattggtga aacggttgct ttgactaagg ccggacgtaa
    14341 ttatgtcggt ctttgccctt ttcatgggga gaaaacccca tctttcaatg tgattgaaga
    14401 taagcagttc taccattgtt ttggatgtgg taagtccgga gatgtattca agtttgtcga
    14461 agaagttcgt ggtgtttctt ttgcagatgc ggcagctatc ttagctgaga aggcagggtt
    14521 tcaaatagat gtaactcctt cctatcatca agaggagaaa agggttagtc cgcatcaggt
    14581 actgtatgat attcatcggg atgctgcaaa gttttatcat gcccttttga tgacaactaa
    14641 aatgggtgag gaagctagag cttatctaca ccaacgtggc ttgacagatg atgtcataaa
    14701 aacattccag ctaggcttag ctcctgccga acagaatatt ctttaccaaa aactatcagg
    14761 tcaatatgac gaagaaagtc tattgaattc gggtttgttc aatccaagtg agaataatat
    14821 tatttatgac gcctttcaag cgaggattat tttccccttg gcggatgaat atggtcgaat
    14881 tgtagctttt tcaggtcgga tttggaccga agaaaatcga aacaataaac aattagccaa
    14941 gtataaaaac tctcgtagta ctgcgatttt caataaaagc tatgaattgt atcatttgga
    15001 caaggctaaa gcggttatta agaagcaacg tgaaacctat ctcatggaag gttttctaga
    15061 tgttattgct gctcatcgtg tagggattga taatgcagtg gcttccatgg gaacagcttt
    15121 gacaagagag catgttgcac acctagctaa gttttgtaag aaaattgttc tgacttatga
    15181 tggggataag gctggacagg ctgctaccat gaaagcgttg gacgaactac aagattttca
    15241 ggttgaaatc gtgagcttgc cagataatat ggacccagat gaatttttgc agaaaaattc
    15301 ggaagaagcc ttgcaacagg ttttaaccaa gtcacgaatc agcgatgtag aatttttgat
    15361 tcaatacttg aaacctgaaa atcctgacaa tctacaaatg cagattgagt ttgtagataa
    15421 gattgcacca attattgcca aagtatcatc cattacagct caaaattctt atatttataa
    15481 ggtggcggat ttactttctg actttgatta taatcaggtg gaacaggcag taaatgctgt
    15541 tcgtctgaat cagcgccagg agagaacaca acaggtattt caatcacaga ctggtcagtc
    15601 ttatttgcca ccagtccaaa cgattgctcg tataacgagt cttattcgaa cagaaaacca
    15661 tttactttat cggatggttg aacatcctta tattctcaat gagttccgtt tacgagaaga
    15721 tttttatttt gcgacgccag aattgcaagc tatttatgat atgttaaaaa aatctgggga
    15781 aattaccagt tttgaactat cacagttgaa cgattccgct caacaggctt ggtatcgtat
    15841 gcaggaagaa cgtttacctg atgaagtgtc tccacacgaa atcgaagaat tagaaattcg
    15901 gcgagacaag gaattgttaa agaaggagaa ccagcaccta gcacggaaaa tccgtgaaca
    15961 ttcccatgtg ggaaatgcag atattgccct cgatgagttg caaaaactcc tcgatagaag
    16021 aagacaaatg gagtaaatat gacaaataaa aaagataaaa aaacagaagt aactactttt
    16081 gatgtacaag ttgccgaatt tatccgtaac cataaaaaac aaggttcagc tacagacgat
    16141 gaaatcaatg accaactggt tattccattt acgcttgatg ctgacggaat cgatgatttg
    16201 ctccaacgta ttcaggacgc agggatttcg attgttgata aagaagggaa cccttctgct
    16261 cgtgctatgc aggtagagga agaaccagaa ttatctgatg aagaattgct cggaagcact
    16321 tctgcaaaag tgaacgaccc agtccgcatg tatttgaaag aaattggtgt tgtacctctt
    16381 ttgaccaacg aggaagagca agaattggca ttggcggttg aggcaggtga cccagaagcg
    16441 aaacaacgtt tggctgaagc caacttgcgt ttggttgtat ccattgctaa acgctatgtc
    16501 ggccgtggta tgcagttcct tgatcttatc caagaaggaa acatgggctt gatgaaggct
    16561 gttgataagt tcgactactc taaaggtttc aagttttcaa cctatgcaac ctggtggatt
    16621 cgtcaggcta tcactcgtgc cattgcggac caagcgcgta caatccgtat ccctgttcac
    16681 atggtagaaa ccattaacaa attggtccgt gaacaacgca atctcttgca ggaattgggc
    16741 caagatccaa ctccagagca aatcgctgag cgtatggata tgacgcctga gaaagttcgt
    16801 gaaatcctca agattgccca agagcctgtt tcactcgaga ccccaattgg tgaagaagat
    16861 gatagtcatc ttggagattt tatcgaagac gaagtcattg aaaatccagt tgattacaca
    16921 actcgtgtcg ttcttcgtga acagttagat gaggtattgg atactcttac tgaccgtgag
    16981 gaaaacgtat tgcgtcttcg ttttggttta gatgatggta aaatgcgtac gcttgaagat
    17041 gttggtaaag tctttaacgt aacccgtgaa cgcatccgcc aaatcgaagc caaagccctc
    17101 cgtaaactcc gccacccatc ccgcagcaaa ccactaagag attttattga ggattgattt
    17161 tgtctgggag acaaaatcaa ccgctcgctg aaaacaggaa acgagcgaga ttttaaccgc
    17221 tccccttgaa attagaaagg gagcgtaacg tccagtggac tttttgacac aaacttcgtt
    17281 tgtttctttt ctagtattga acttgtgaaa aagaaagaga gaaaaatgac gtacacagaa
    17341 gatcaaatta aagacattca ggagcgtatt tttcatgctc ttgaagatgt gattgaccct
    17401 gagctaggta ttgatattat caatttaggg ctaatttatg aaatccgatt tattgagggc
    17461 aaggctgaaa ttgatatgac cttgacgacc atgggttgtc cattagctga tctaattacc
    17521 gatcaaattc atgatgtatt gaaggatgtc cctgaagtaa cagaagtaga tgtgagactg
    17581 gtttggtcac cagcttggac cgttcaaaaa atgagtcgtt atgctcgaat tgcattagga
    17641 attaaataaa aaaacaaaat ggtttcgaac gtttgaagcc gtttttttat tatggcttcg
    17701 agccagtttt tctcgtagag aaaaacaaga aagccaccag ctatgctggt ggctgccaag
    17761 gctttgagtt tccatttctt tttcctgtta taatctaatt gttcaggtta gatcaaggag
    17821 gaaaaagaaa tggctaaaac cagttacagt ttatcacata ctaaatggat gtgctctatc
    17881 acatagtttt cacacctaag taccgtagaa aatccattta ctacaaaata aggcaggact
    17941 taattgatat tttccgtcat ctatgtcgat gcaaaggcgt ggacatcacg tcatacgcat
    18001 gaaaaatttc ttctctcctt ttgtccccgg aaataactgc tttaaactta gtatctacct
    18061 ttttacaagc accttatccc cgatttccaa ataattgtgg caaataatcc tccaaatgga
    18121 cagaaatata gcgttgtttg cggcggtaac tcaatttctc cttagggaag gtcatcattt
    18181 gtaagagatg aagacaagcc ttacgaatag catttaaatt gaaagcagct cgtttatcta
    18241 aggtttggtt cttatcttct cggtaaacca catctaacaa tcaatgtagg ctctcaaccg
    18301 accaatgacc acgaacaacc tgagaaaaag tttgcacatc gcccttgaaa ctaaggataa
    18361 agtaacggac ctcttcagtg atgacaccat ctttatcaat gatattctta gtcataccaa
    18421 tcccacgaag ttttttccat ttcggatgtc gttggctcag ccatttcaca tcgtgagaaa
    18481 cccagtagtc cctcacctca atctgactgc gtgccttttc aatggtctga taatgacagc
    18541 ctttctctgt caacgtagat aacaatttgg cgtcactaaa atagaggtca atatcctcat
    18601 ggagattgcc ttgatttcct ttgactgcca agcaataatc acccttaccg ctgataatca
    18661 catccgcaat gtctgtctag gtgcccatgg catcaatcgt gacaacactc ttacgaaggt
    18721 ctagctgaca caagaggcga ggaatggctg tgatttcatt acttttatcc tcaacagcta
    18781 cctgcccaag gctaatccga ttaccaccat cataagcagt gacaatatga gtaggagatt
    18841 ggtgtttccc tcggttcccc cgaatcgttt ttccgtcaac ggcaatcaat tttgaaaaat
    18901 cagttgtttc cgaactagct tcgaaggaca gtttcagttc ctttaagaaa tctggattga
    18961 ccatactcac aacacgttcc aaggtgtcat gagaaagaca gccgacactc aagtcaacgt
    19021 attctcccaa aacagactcg ttcatttcta tgaaatcttc catctctttc cacgtttcaa
    19081 cccctgccaa ttgacaagcg aaaactagaa acagaatagt ggataaggga taacgaattt
    19141 tccatgcttg acggctgttg tactcctctt tgtgctcttc tatggataaa agaaaatcaa
    19201 ttattgtagt tcacctctat tctagtgtac tactttgatt gatctttggt tatgattttc
    19261 gctttctgaa aacgtttttt tcttcatgcg tttggtgtgg tggaaatcat tgagggacac
    19321 atgatgccag accatgttca tatgcttgtc ttgatatccc caaaactttc gatttccgat
    19381 tttatgggat atttgaaaag taaaagtgct ctcatgatat ttgataaaca tgctaattta
    19441 aaatataagt atggaaatcg aaagttttgg gctagaggct actatgtgag taccgttgga
    19501 ctgaacgaaa agacggtagc gaaatatatt cgcgagcagg agaaaaatga catcgcactt
    19561 gataagttaa gtgttaaaga atatgaagat tcattttcag atagtagttt tagaacaaga
    19621 taaaagcccg ttgttacggg cattagtcaa gtaattatag cactaacctg aacgaagttc
    19681 agcgaacgtc tttagacgtc gctggagaga aacggcttat agccggtgta caagccaccc
    19741 gttttcacgg gtggttatga ttttatccta acaattgctg caaccattgg ctgccataga
    19801 tccaaaagaa gctataggcc acaactgaga aagggcgaca aagtaaagta atcataataa
    19861 atttccgata actcatgctt gttaatccag taatcatcac cactatgtca gctggagaaa
    19921 tgggagaaag catgcagaga ataaagaaaa tttcataact acgtttatta tcaattttgc
    19981 tttcatattt gtaaaacgta tcttcagaca tgaagaggag acaaaatttc tttccatagc
    20041 gacgagccaa ccagaaaagg atgatactac cgattgaaat tccaagataa ttgagaaaga
    20101 atccccacca aaaatgaaat acgaggaaac ccacaacagt cgtaacaccg cctggaataa
    20161 tcggaaatac aacttgaata atctgaatag ctaaaaagga gaggctacct aaagcacctt
    20221 ggcttttgat taaatcgctt aagacatttt ggtcgttcaa aatgccaatc ttatagagcc
    20281 aaaatagaaa aatagcggtc ccgataaggg tcaaaatact taatacttga atggttttt
//
LOCUS       DBNFCO010000037        20320 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.037, whole genome shotgun sequence.
ACCESSION   DBNFCO010000037 DBNFCO010000000
VERSION     DBNFCO010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 20320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20320
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.037"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(<1..4052)
                     /locus_tag="AC1PIV_001099"
     CDS             complement(<1..4052)
                     /locus_tag="AC1PIV_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HIP6612127.1"
                     /translation="MFPNGNVANSIPQSIELYVADGTKAMSYSKDSLEKLTYKGTSNN
                     GNIHHYYLPGTDIGISVRVYSERNSYPAFDGFESTHTIEFYQEGWKLGNKAIVVRLKE
                     RKKFQKNGLYYNGMSVPWNSPVMGGGRTTNIYRREGDTVSQGGAYPVDWYGFKLKKVG
                     IKNGQKIPLSGAIFTLYKGNEPYRTAVSDDNGDIQFSEIIGGTYTFKETSAPSGYILD
                     PTEHTIVVTDNQNITIDGKKYDVNKPTEVVNTKSTTLQINKFEFGESKPLKGAVFRLQ
                     SKNGGNYDVTIGDVLPASQFIFSNLAKGIYTLTETKAPAGYKTIPPLDIEVYEENGEL
                     KVRKLTDTSNTQTGAVEVVNGNFSINVVDEDFSTEFTKVNEQGQPLADAVFELRQITQ
                     TGYKRVLTGLTSNSQGKLRVDHLQGGITYELWETSAPAGYSKLTTAAARFTVSETGTI
                     SFESGTSERIINRPPTYKVKVQKIDALTGQKVTVQTRIGITDSQGNVIDGQIANFDNG
                     EFSFPKNFTPGTYYIKEEKTPSGYIGLSGLVPFTIRADGIVEVNSDYLEGIDVTTSSP
                     DTITIKVKNYPLGKFKVSKRVKGISDLTNLITGQMTFTLTKNDDVNFAPIVKQQAANQ
                     DFVFENLQPGVYTLTETQAPSGYVKSTENYTIYVNRDGSVRFYSDSDISSHIARGLHV
                     IKSAEIAMASTYGSSTEDKALDGDLTTGALYQLPSSTLNEGQWWGVNLGSPQRVTQIR
                     FAQGKNTTNGSDHDKMDSYALEYSPDGITYQSIGNFTETDLTQTVDIYAQYIRVRNLQ
                     TGTNRWLGIRELQVSVRDATQTIEAGGSDAAANVIKIGNIENPEFKIEKVDANNKQIS
                     KPVTFKLYKVDDSTTEATVSSTSLDDTNLVQTLTFTGQSSLTRLTATALGKYVLVETQ
                     APEGYDGLSAPVLLELYETTQAYAVTQQKAVTRFRVLSQTNSVSVTDLPGVSGALANA
                     ISIKVKNNERRYNLKIKKRDYHHPTLGLNARFELVTEAGHPVVIDGVNMKGDTNSADN
                     SITFSNLPVGVYILKETVVPTGGYRPVNQLQDTKFEIRPDGSLQILESDSNMVTVDTS
                     QGATFEITIKNFKQFKFRLQKTDNRDENHLLNGATFKIYSDPNNDGVEDTEVASGVTT
                     NGLFETSLSFGYYILEETVAPTGYQLNPKKYRFQINHDGTTKLHNGDNQVTLAERVDG
                     DNVILFNMKNTKQTTHIKLAKRSYSDPTQRLVATFELRESDNPQATAVVKTTTTTGDE
                     VLFDNLAVGKTYILKEIVAPDGYQKIEKEFHINIGADGAISIQDGEDLVSLDNMDNHL
                     IIVKNLRKGEYPKTGGMGIIPYIALGGVMM"
     gene            complement(4093..7092)
                     /locus_tag="AC1PIV_001100"
     CDS             complement(4093..7092)
                     /locus_tag="AC1PIV_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HIP6612128.1"
                     /translation="MIEFRKKAVQLASLMSVFFLCTYSFTDAMYIMAESLSTDGASTI
                     RRTYIEDKKEDKDRLNIELVESLSSPKTIGQKITIDKQSLATQNFNEKGIVVITQKGL
                     ELKKDDLEKGWKLDESYNEKDLAITKSETEKRSLSNELDVLSKTVEELPVYGENYHSY
                     RLLPTTELDYSADNVSLTLSFTKVSEVIKGELVAVVDAEHIAYFKAEPSVFKEYSQVN
                     EKPSSTEDVNVVSPSQDPPVSETKENVPDNPESQGSSTVPESEQAVDALVEQRGVICI
                     KLTKSSSEQEEGIEDTENEAIEGATFEVRNVESENLVYTGQTDKDGLLTISNLPLGNY
                     AVIQKSTIDGYEISATKEVVELTVAQSRQTVSISNSPKNPLEGLMLNSILDSSLIPRS
                     ARVARSLLDTSLLDNPTVTGNANATTTTTVFGNKTTTITREESNIKYIFKPITISIPG
                     VYQSYSQDGVLKKKEVVVDSNTNTTKIIWEYTTTVGGVNSNITSIRNAFSITTDSGLG
                     EPKITSIMKDGVAITPNTTYYGNFDNFKSATDNLPVGNGTYVYTIETPVVIPSDNYSL
                     DYRSEVTVDAPKGSKLTYNGTSVTLTQKETRTLSTADTITLPAKNDGGPLGDLKVDTV
                     NTSNTNRTIGKYRDNDDKVIEWTSSQLNDTSTTQSFTFDVALDSSQAAHEYKVYIYEP
                     SNGTYTETKAEKVATPGNQITVDNVPAGAVALVKTVTNVKDEKVNHTISGAQLEALKG
                     DIKIQKNWEADSDKVDVTFTVNGGSLTNRKETLSANNTQITIANVDKFSGMRSTATKK
                     RIYYDVTEAVPSGYILSSAQTDWENLYYVFTNKKDNTTTPVFPPDTCGNYGVSSIDLV
                     SINYVMYKSGSKIWGGFDGSMKMNLKIPAFARAGDSFTLELPPELKLSHVANPNVAWS
                     TVSANGKVIAKVYHEKDNLIRFVLTTEAYSVQEYNGWFEIGVPTSNVIKINNRETTEL
                     YKTGVLPNLPEWYTTTTRNQTLIKRSR"
     gene            complement(8388..8510)
                     /locus_tag="AC1PIV_001101"
     CDS             complement(8388..8510)
                     /locus_tag="AC1PIV_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612129.1"
                     /translation="MFALGTIINTLAIALAGLLGSWFGHLLKERHQSGLTMGNV"
     gene            complement(8514..9260)
                     /locus_tag="AC1PIV_001102"
     CDS             complement(8514..9260)
                     /locus_tag="AC1PIV_001102"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002941981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HIP6612130.1"
                     /translation="MQQYFVNGRAPQGMFQISDKDTAKHMFSVMRLQAGDQIVLVFDD
                     GIKRLARVVDSQSQSVEIIEELTDNVELPISVTIAMGFPKGDKLEFVAQKATELGMSA
                     LWAFPADWSVVKWDGKKLAKKAEKLEKIAQGAAEQSKRNRIPAVRLFEKKSDFLAQLA
                     GFDQIILAYEEAAKEGEQANLVKILSGLEIGQSVLVIVGPEGGVSPEEVAAFEGAGAV
                     KTGLGPRILRAETAPLYALSTISYATELLR"
     gene            complement(9262..10215)
                     /gene="prmA"
                     /locus_tag="AC1PIV_001103"
     CDS             complement(9262..10215)
                     /gene="prmA"
                     /locus_tag="AC1PIV_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HIP6612131.1"
                     /translation="MNSWQELTIHVHRDAEEAVSNLMIETGSQGVAISDSADYVGQED
                     CFGELYPEVEQSDMIAITAYYPDTVDIEEVKADLATRLADLTGFGLETGQISLESQEL
                     AEEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIRLDPGMAFGTGTHPTTKM
                     SLFALSQVLRGGETVIDVGTGSGVLSIASSLLGAKEIYAYDLDEVAVRVAQENIDLNA
                     NTSNIHVAAGDLLRGIDIKAEVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIADK
                     WDMVRASAEAAGFFLETHMTQGEWNCCVFKKTADRSGVIGG"
     gene            complement(10737..11090)
                     /locus_tag="AC1PIV_001104"
     CDS             complement(10737..11090)
                     /locus_tag="AC1PIV_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009910982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HIP6612132.1"
                     /translation="MVHEMLLAPKPFEMMKSGQKTIELRLYDEKRKHIQIGDRIRFYC
                     TENQTQTIEVQVLELHIFDNFAQLYKELDLLSCGYTQSSIREAKPEDMEVYYSREQLE
                     QYGAVGIELRVIDSI"
     gene            complement(11092..11562)
                     /locus_tag="AC1PIV_001105"
     CDS             complement(11092..11562)
                     /locus_tag="AC1PIV_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HIP6612133.1"
                     /translation="MAKHGFLDVLEAALDKHFTYDYELNWDKKNHAIELAFILEAQNA
                     AEIETVDDEGNASSEDIFLEEYVLFYNQDKSRFDEEDYLVALPFDAKKGFSAEFLTYF
                     ASFLKDTADQGLDDLMDFLADPEAQEFAISWDGEAFEKGKADLVEGEFYPYPRY"
     gene            complement(11564..11899)
                     /locus_tag="AC1PIV_001106"
     CDS             complement(11564..11899)
                     /locus_tag="AC1PIV_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG nucleotide pyrophosphohydrolase
                     domain-containing protein"
                     /protein_id="HIP6612134.1"
                     /translation="MTELTVSVLEEYLRDHYGTTVPEQSLFMKLVEEIGEVAELLNQR
                     AGRKMMDSEDDSSARLAEELADVIHYAVALAAVNQLDLTKSILEKDERASVKYGREIN
                     LLEFIEKRK"
     gene            11969..13255
                     /locus_tag="AC1PIV_001107"
     CDS             11969..13255
                     /locus_tag="AC1PIV_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HIP6612135.1"
                     /translation="MPANLALRMRPKSIDEVIGQEHLVGPGKIIRRMIDANMLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATTDNQKRLQEIAEEAKFSGGLVLLLDEIHR
                     LNKTKQDFLLPLLENGNIIMIGATTENPFFSILPAIRSRVQIFELQPLQTSHIRQALE
                     LALTDSERGFDFPITIEPEALDFLANATNGDLRAAYNSLELAVLSTKECDDGSRYIDL
                     DAVENSLQKSYISMDKNGDAHYDILSALQKSIRGSDVNASLHYAARLIEAEDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALEAAQKIGFPEARILIANVVVDLALSPKSNSAYL
                     AMDAALADLRKNGHLPIPNHLRDGHYAGSKELGNAIGYQYPHAYPEKWVDQQYLPDKL
                     LHADYFTANDTGKYERALGMTQEKIKNLKKNRRQNP"
     gene            13357..13550
                     /gene="ssrS"
                     /locus_tag="AC1PIV_001108"
     ncRNA           13357..13550
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="AC1PIV_001108"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            13559..13631
                     /locus_tag="AC1PIV_001109"
     tRNA            13559..13631
                     /locus_tag="AC1PIV_001109"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:13592..13594,aa:Lys,seq:ctt)
     gene            complement(13737..14294)
                     /gene="nrdG"
                     /locus_tag="AC1PIV_001110"
     CDS             complement(13737..14294)
                     /gene="nrdG"
                     /locus_tag="AC1PIV_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HIP6612136.1"
                     /translation="MNNPKPQEWKSEELSQGRIMDYKAFNFVDGEGVRCSLYVSGCLF
                     HCEGCYNVATWSFKAGIPYTKELEDRILADLAQPYVQGLTLLGGEPFLNTGTVLPLVK
                     RIRKELPEKDIWSWTGYTWEEMMLETPDKLELLSYLDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLQEKRVVLWDKLKK"
     gene            complement(14481..14975)
                     /locus_tag="AC1PIV_001111"
     CDS             complement(14481..14975)
                     /locus_tag="AC1PIV_001111"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIP6612137.1"
                     /translation="MELRRPTIADKETILEMLAEFEKAGSAMDGGFISKDVDFEEWIF
                     RNKDYETGLNLPDGFVPSIQYVSFDQTGRALGFLSLRLRLNDFLLNKGGHIGYSIRPT
                     ERGKGYAKDQLRLGLQEAATKNISKVLVTCLTDNQASRCTIVACGGVLEDVRDGVERY
                     WIED"
     gene            complement(14977..16323)
                     /locus_tag="AC1PIV_001112"
     CDS             complement(14977..16323)
                     /locus_tag="AC1PIV_001112"
                     /EC_number="3.1.-.-"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA];
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0009166 - nucleotide catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HIP6612138.1"
                     /translation="MDYTDISILHTNDMHSYMENFPKKAQLIADIRARNEQKGIPTFV
                     FDSGDLFSGNIFFNMYRGVKEIELMNQIGCQAMTLGNHEFDHGDELLSRLDDYAQFPI
                     VSSNLRYRDVEVADELVLLEDVLEFDMNGNPLYVLGLTTLETQEVASPSENVIFEGHK
                     QALRRVVDQVLAKDPQAHMVLLSHLGYDEDVHLAKDFPELNVILGGHTHTILKEPTQV
                     GSVSICQAGQYGRFIGHLSLRCYADGRHEVLAYDLIEVEKLTQEDRAVKAIIDQMKSE
                     RDAVFSQPIAILPQALDGERDSIRQGLSTLAPVICQALFEQASQLGLQVDGAVINGFG
                     IRASLSAGPIFYSDLVKVLPFSKRVLLVRIKGRDLLSSIQTGLHPQMWGIVPGSEGFV
                     VNGRAAESDKDYQIVTNSFVWSGKDNYDDFHKAEIVQDLGLDIDIISEFFKRQYGD"
     gene            complement(16325..16459)
                     /locus_tag="AC1PIV_001113"
     CDS             complement(16325..16459)
                     /locus_tag="AC1PIV_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612139.1"
                     /translation="MGKYQLDDKGKALVTRYHEKNSNVKQDKKARVQELLKQAKNKKK
                     "
     gene            complement(16558..18729)
                     /gene="nrdD"
                     /locus_tag="AC1PIV_001114"
     CDS             complement(16558..18729)
                     /gene="nrdD"
                     /locus_tag="AC1PIV_001114"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HIP6612140.1"
                     /translation="MNVQENVLPSIELLVLKRDGRTVSFDQDKIFSALQRANQELEHP
                     VSEAGLKIVLEAVLAEIGRRFEKDVQIYEIQTVVEQELLKAHLYDLAELYIQYRTRRD
                     FRRHQATDINFEIHKLLSKDQSVVNENANKDADVFNTQRDLTAGIVGKSIGLKLLPAH
                     VANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLAQGFKIGNADVESPKSIQTATAQ
                     ISQIIANVASSQYGGCSADRIDEVLAPYAELNYQKHLKDAEDWVLADKQEEYARAKTQ
                     KDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSWFEREIQKAILNIRIKGLGREG
                     RTAIFPKLIFTVKRGLNLESDSPNYDIKQLAIECATKRMYPDMLSYDKIVELTGSFKV
                     PMGCRSFLQGWKDENGQDVTSGRMNLGVVTVNLPRIAMESAGDKDKFWEIFAERMAIA
                     KDALVYRVERVKEATPANAPILYQYGAFGKRLAKTDAVDEVFKNRRATVSLGYIGLYE
                     VATVFYGGEWETNPEAKDFTVDIIKKMKALVEDWSDEYGYHFSVYSTPSESLTDRFCR
                     MDTEKFGIVKDITDKEYYTNSFHYDVRKNPTPFEKLDFEKIYPAVGASGGFIHYCEYP
                     VLQQNPKALEAVWDYAYDRVGYLGTNTPIDHCYACDFEGDFEPTERGFKCPNCGNSDP
                     KSVDVVKRTCGYLGNPQARPMVKGRHKEISARVKHMNGSSL"
     gene            19113..>20320
                     /locus_tag="AC1PIV_001115"
     CDS             19113..>20320
                     /locus_tag="AC1PIV_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /protein_id="HIP6612141.1"
                     /translation="MLDQIKAHLLDSINDIVSIANQFVLHPEKDFSRKSQLTMETMIQ
                     AILTMGGNTLAKELLDLDLPVSQSAFVQRRYQLKHQAFKALFANITSKIPTFKDLPIL
                     AVDGSDVVLPRNRSDKTTTFQTGPHHTPYTLIHINALYNLEQEIYHDLRIQNNREVDE
                     RAAFIDMMESCPFEQALVIMDRGYESYNVMAHCQERNWSYIIRIRDGNHSMKSGFNLP
                     DTPCFDEEFDLNICHKQTNVMKELYRDFPNQYHFLPHNASFDLLPNSSRKSDPISFYD
                     LHFRMVRLEIKPGFFETLVTNTDYSPEKLKDLYAYRWGIETSFRDLKYSIGLTHFHAK
                     KKEGILQEIYAHFINFNVCKWLTSHVAIKPSKLKQAYKICFSDAVYACRKFLREELTS
                     FQLETYIAKH"
BASE COUNT         5640 a         4671 c         3780 g         6229 t
ORIGIN      
        1 aacatcatca ccccccctaa tgcaatatat ggaatgatac ccataccacc tgttttcgga
       61 tattctcctt tgcggaggtt tttcacaata atcaggtgat tgtccatatt gtctagactg
      121 acgaggtcct ctccatcttg gatagagata gccccatctg cgccaatatt aatatggaat
      181 tctttctcaa tcttttgata accgtcaggg gctactatct ctttcaagat ataggttttc
      241 cctactgcta aattgtcaaa gaggacttca tcccctgttg tagtcgttgt ttttacaact
      301 gctgtcgctt gaggattgtc actttctctt agttcaaacg ttgctacaag acgttgcgta
      361 ggatcgctat aagaccgttt agcaagtttg atatgggttg tttgttttgt attcttcatg
      421 ttaaagagaa taacattgtc accatctacc ctttcagcta aggtaacctg attatctcca
      481 ttatgaagtt tggtcgttcc atcatggttt atctggaaac ggtatttctt aggatttaat
      541 tgatatcccg ttggcgcaac agtttcttcc aaaatgtagt aaccaaaact caaagatgtt
      601 tcaaagagac catttgtcgt cacaccacta gcaacttcag tatcctcaac accatcgttg
      661 tttggatcgc tgtaaatttt aaatgttgca ccatttagaa ggtgattctc gtcacgatta
      721 tctgtttttt ggagtctgaa cttaaattgc ttgaagttct tgatggtgat ctcaaaggta
      781 gcaccttgtg acgtatcaac tgtcaccata ttcgaatctg actctaaaat ttgtaaacta
      841 ccatctggtc ggatttcaaa tttggtatct tgtaattgat taacagggcg atagcctccc
      901 gtaggaacaa ctgtctcttt caaaatatag acgccaactg gcaagttcga gaaggtgata
      961 ctgttgtcag cactatttgt atcccccttc atattaacac catcaattac aactggatga
     1021 ccagcctctg taacaagttc aaagcgcgca tttaaaccaa gagtcggatg gtgataatca
     1081 cgttttttga ttttaagatt gtacctacgc tcgttatttt tcactttaat gctaatcgca
     1141 tttgcaagag caccactaac accaggtaaa tctgttacac taaccgaatt agtttgactt
     1201 aaaactctaa aacgtgtcac agctttctgt tgcgttaccg cataagcttg cgttgtttcg
     1261 tataactcca acaataccgg tgcactcaaa ccgtcataac cttctggtgc ttgtgtctct
     1321 acaagaacat atttgccaag cgctgtcgca gttaatcgtg tcaaactgct ttgacctgta
     1381 aatgttaagg tttgtacgag attggtatcg tcaagagagg tacttgatac agttgcctct
     1441 gttgtactat cgtcaacttt atagagctta aaggtaacag gttttgagat ttgcttatta
     1501 ttcgcatcta ctttctcgat tttgaactct ggattttcga tgttaccgat tttaataaca
     1561 ttagcggcag catcacttcc acctgcttca atcgtttggg tagcatctcg aacacttacc
     1621 tgcaattctc ggattcccaa ccatctattc gttcccgtct gtagattccg tacacgaatg
     1681 tattgagcat agatatctac agtctgagta aggtcggtct cggtgaaatt accaattgat
     1741 tgataggtga taccatccgg tgaatactca agggcatagc tatccatctt gtcatggtca
     1801 ctaccgtttg tggtattttt accttgagca aagcgaattt gcgttacgcg ctgaggcgaa
     1861 cccaagttca ctccccacca ttgtccctca ttcaaagtcg aacttgggag ttggtacaag
     1921 gcaccggttg tcaaatcacc gtccagcgcc ttatcttctg tactagagcc ataggtagag
     1981 gccatagcaa tctctgcaga ttttatcaca tgcaaaccac gtgctatgtg actacttata
     2041 tccgagtcag aatagaaacg cacgctgcca tctctattaa cataaatcgt gtagttttct
     2101 gtcgatttga catagccaga tggagcttgt gtttctgtca gagtatagac cccaggctgg
     2161 aggttttcaa aaacaaagtc ttggtttgca gcttgctgtt tgacgatagg ggcaaagttt
     2221 acatcgtcat tctttgtcaa agtaaaggtc atttgtccag tgataaggtt ggtcaaatca
     2281 ctaatccctt taacacgctt gctaactttg aattttccga gtggatagtt cttgactttt
     2341 atcgtaatcg tatctggcga gctcgtcgtc acatcaatac cttcaagata atcactattc
     2401 acttctacga taccatctgc ccgaatagtg aatggtacca aacctgataa gccaatataa
     2461 cccgatggag ttttttcttc tttgatatag taagttcctg gggtaaagtt tttaggaaag
     2521 ctaaattctc cattgtcaaa gtttgcaatt tgcccatcaa ttacattccc ttggctatcc
     2581 gtaataccaa tacgtgtctg cacagttact ttctgtccag tcagtgcatc aattttctgc
     2641 actttaactt tataagttgg agggcggtta ataatacgct cactagtacc agattcaaaa
     2701 ctgatagttc cagtctcaga taccgtaaat cgtgccgcag ctgttgttaa cttactataa
     2761 cctgctggcg cactagtttc ccaaagttca taggttatac caccttgcaa gtggtccaca
     2821 cggagcttgc cttgactatt tgaagttaag cctgttagaa ctcgtttgta gcctgtttgg
     2881 gttatctgac gaagctcaaa cactgcatct gcgagtggct gaccttgctc atttaccttg
     2941 gtgaactcag tactaaagtc ctcgtcaaca acatttatac taaagtttcc gttgacaact
     3001 tctaccgctc ccgtctgtgt attggaagtg tctgttaatt tacgtacttt taactctcca
     3061 ttttcctcat aaacctcaat atcaagagga ggaatcgttt tataacccgc aggagctttt
     3121 gtctccgtca aagtataaat gccttttgcg aggttagaga aaataaactg acttgcagga
     3181 agaacatctc ctattgtgac atcataattt ccaccatttt tactttgcag tctaaagaca
     3241 gctcctttca atggcttact ttcaccaaat tcaaatttat tgatttgaag tgtagttgat
     3301 ttagtattaa caacttctgt tggcttattg acatcgtatt ttttcccatc aatggtaata
     3361 ttttgattat cggttacaac aatagtgtgc tctgtcggat ctaagatata accagatggt
     3421 gcactagttt ccttgaaggt gtaggtgccg ccgattatct ccgaaaactg aatatctcca
     3481 ttatcatctg aaactgcggt tcgatatggt tcatttcctt tatataatgt gaaaatcgca
     3541 cctgaaagtg gaattttctg accattttta attccaacct ttttcagttt aaaaccatac
     3601 caatctacag gataagcacc accttgtgat actgtatctc cctcacgacg atagatatta
     3661 gtggttcttc ctccacccat aactggacta ttccatggta cactcatacc attatagtac
     3721 agaccatttt tctgaaactt tttccgttct tttagacgga ctacaattgc tttattacct
     3781 agtttccaac cttcttgata aaattcgatt gtatgagtgc tttcaaatcc atcaaaagcc
     3841 ggataagaat ttctctcaga ataaactcga acagatattc caatatccgt acctggtagg
     3901 taataatggt ggatattccc attatttgat gttcctttat aagtgagctt ttctaagcta
     3961 tccttagaat aggacatagc cttggtacca tctgctacat agagttcgat agattgagga
     4021 atactatttg ctacatttcc atttggaaac aactctaaac ctggatgaag aaaatcataa
     4081 aattttctcc tattacctag acctcttaat caatgtctga ttgcgagtag tcgttgtata
     4141 ccactcggga aggtttggaa gcacccctgt tttatatagt tctgtagtct ctctattatt
     4201 gattttgatc acattactgg ttggaactcc aatctcaaac caaccattgt actcttgtac
     4261 ggaataagcc tctgtagtca gtacaaagcg aattaaatta tctttttcgt gataaacttt
     4321 tgctatcacc ttaccatttg cagacacagt ggaccatgca acattaggat ttgcaacatg
     4381 acttaacttt aactctggtg gcaattctaa agtaaatgaa tctcctgcac gcgcaaaagc
     4441 aggtattttc aagttcattt tcatcgaacc gtcaaaacca ccccaaattt tagaacctga
     4501 tttatacatg acatagttga tgcttacaag gtctatactg cttaccccat agtttccgca
     4561 agtatctggt gggaatactg gtgtcgtggt attatccttt ttatttgtaa agacatagta
     4621 aagattttcc cagtcagtct gtgcgctaga aagaatataa cctgatggaa cagcttcggt
     4681 cacatcataa tatatcctct ttttagttgc tgtgcttctc ataccagaaa acttatcaac
     4741 attagcaatc gtaatttgtg tattatttgc gctaagtgtt tccttacgat tagttaaact
     4801 tcctccatta accgtaaagg tcacgtctac cttatcacta tcagcctccc aattcttctg
     4861 gatttttata tcacctttca gcgcttctag ttgtgctcct gaaatggtgt gattaacttt
     4921 ttcgtctttc acatttgtca ctgtcttaac caaagcgacc gcacctgccg gaacattgtc
     4981 aaccgtaatc tggttcccag gcgtagcaac cttttcagct ttagtttcag tataagttcc
     5041 attacttggt tcatatatat aaaccttata ttcatgggca gcttgtgagc tatctagagc
     5101 aacatcaaat gtaaaacttt gggttgtcga cgtatcattt agttgtgaac tagtccattc
     5161 gatgacctta tcgtcattat cacgatactt accaattgta cgattggtat tggaagtatt
     5221 gaccgtatct acttttaagt cccctagagg accaccatca tttttagctg gaagcgtaat
     5281 agtatctgct gttgataagg tacgtgtttc cttctgagtt aaggtaactg atgtgccatt
     5341 ataggtaagc ttgctgccct ttggagcatc aacagttact tccgaccgat aatccaaact
     5401 atagttatca cttggaatca ccacaggagt ctcaatcgta tagacatacg tcccgtttcc
     5461 aactggtaaa ttatcggtag ctgacttaaa attgtcgaaa tttccgtagt aagtcgtatt
     5521 gggcgttatt gcaactccat ccttcatgat agaagtaatt ttaggttcac ccaaaccaga
     5581 gtcagttgtt attgagaagg catttctaat ggaggtgata ttgctattga caccgcctac
     5641 cgtagtagtg tattcccaaa tgatttttgt tgtattggta tttgagtcaa ccactacctc
     5701 ttttttcttc aagacaccat cttgtgaata gctttgataa acacctggaa ttgaaattgt
     5761 aataggttta aaaatgtatt ttatgtttga ctcttcacgc gtgatggttg ttgttttatt
     5821 cccgaatacg gtggtcgttg tagtggcatt tgcatttcct gtcacagtag gattatcaag
     5881 taatgaagta tcaagtagcg aacgtgctac tctcgctgaa cgcggtatca aagatgaatc
     5941 caatattgag ttcagcataa gtccttctaa aggattttta ggggagttgc taattgagac
     6001 ggtttgtctt gattgagcta ctgttaactc cactacttct tttgtggcag aaatctcata
     6061 gccatctatg gtagattttt gaattaccgc atagtttccc aacggaagat ttgaaatcgt
     6121 taggagacca tctttatctg tctgaccagt ataaacaaga ttttcacttt ctacattacg
     6181 cacctcaaat gtagcacctt cgatggcttc attttcagta tcctcaatgc cctcttcttg
     6241 ttcagaacta gattttgtta atttgataca gataactcct cgttgttcga ccaaagcatc
     6301 caccgcttgc tctgactctg gaactgttga acttccttgt gattctggat tatcaggtac
     6361 attttctttt gtttcagaga cgggtgggtc ttgagaagga cttactacat tgacatcctc
     6421 agtagatgaa ggcttttcat taacttgaga atactcctta aagacactcg gttcagcttt
     6481 aaaatatgcg atatgttccg catctactac cgctactaac tcccccttaa taacctcact
     6541 gaccttggta aaacttaaag tcagacttac attatctgcc gaataatcca attctgttgt
     6601 tggcagcagt ctataggaat ggtagttttc tccatacact ggaagttctt ctacagtctt
     6661 tgacaataca tctaattcat ttgaaagaga gcgtttttct gtctcactct ttgttatagc
     6721 taggtccttc tcgttatatg actcatctag tttccaacct ttttctaaat catctttctt
     6781 taactctagc cctttttgag tgataactac tatacctttt tcgttaaaat tctgtgtagc
     6841 taaactctgc ttatctattg ttattttttg acctatagtc tttggactag acaacgattc
     6901 tactaactca atatttaatc tatctttgtc ctcctttttg tcttcgatat aggtgcgtct
     6961 tattgttgaa gcaccatcgg tcgacaaact ttctgccatg atatacatcg catctgtaaa
     7021 actatacgtg catagaaaaa aaactgacat taaactagct aattgaactg ctttctttct
     7081 aaattctatc atctcgtact ccttggtttg tgtctaaatc tgctaaagtt gagatacagg
     7141 gacattatct ttttcggttc taaatataaa caaaatcaac tttaatactt attaagctta
     7201 catgaaattg atagttcaaa taccattatt tcaatgcact ataatataaa tagcaatcgc
     7261 cgtaagttcc ctgcaatctt cctctagttt tcacttttta caataacact tacacagatt
     7321 ttttccatat acaatcttac ttgatttccc tctaaaatca agcgacattc agcgataaac
     7381 acagaaaaaa tagaaaaaga acatctggaa atgacaaaaa tcaccttaat ataaaaatga
     7441 ccatatttca aaaaatatgc atcacaccat attacatttc aaacactgac tctctaatga
     7501 gtctaggaca aaaagatttg tttttttgaa atacctcatc tggtcattct accgattgat
     7561 aaacaaaaca aaaaacgaac aatactagtt tctagatacc ttaaaactaa ttttgttcgt
     7621 ttttatatac aaatttttaa tttttctcaa aatcattaat agactaattt tagattcgat
     7681 tgaataaaag atgtagctta aatatttcgg cgacgctatt tctgttgcca aaaactcgga
     7741 tttgtgagct attatatata agtctgtcct aaattgtttt tcttgataaa gaattcccga
     7801 actacttaaa aaggactttt taccttttta gcctaatatg catgaagaaa aaattactca
     7861 caggcaatct agcacaaata atagcgcagc taggtaaaaa gtacaacgcc acttctttaa
     7921 gttagtgtca atatctcagt gcagtagttg attgctctag caatctgaga gaattgcttg
     7981 aggttagaaa ttgaacaaac aaagtttgtg ccgagacagc ccaagaaact gtttcagcct
     8041 gaccctagaa atcaaaagtg aggtaaaaaa gttggatata ggatttgtaa aaaaaatcac
     8101 agcaattcgt attttatagt cttttaattt acttttagta cgaggcaatg agccgcaggc
     8161 ataactgaag ttaggcaagg cgagttaacg aagtaataaa agaaaaacta aatgacgata
     8221 cactcaaaat ctaccctaat cagctatgta aggatgagaa gacggactct actaggaata
     8281 gtcgtcttct catccttgcc tggttcttaa ttccattatt gaaaccaatc accatttaac
     8341 tatctatacc ccaataatca aaggattcta acaggttcaa gaaagactca aacattcccc
     8401 atcgtcagtc ccgactgatg ccgttctttc agtaaatggc caaaccaaga tcctagcaaa
     8461 cctgctaggg caatggccaa ggtatttata atcgtcccta aggcaaacat ggactacctc
     8521 aacaattccg tcgcataact aatggtcgaa agagcataaa gcggagctgt ttccgcccgg
     8581 agaatgcgag gacctaggcc tgtcttgacc gctcctgctc cttcgaaagc agctacttcc
     8641 tcaggcgaca cgccaccttc tggaccgacg atgacaagga ctgattggcc gatttctaag
     8701 ccagacaaga ttttcactag attggcttgt tcaccttctt ttgcagcctc ttcgtaggct
     8761 aagataatct ggtcaaagcc tgctagttga gctaggaaat ccgatttttt ctcaaacaag
     8821 cgaacagccg gaatgcgatt gcgtttgctt tgctcggctg cgccttgggc aattttttct
     8881 aacttttctg ctttttttgc cagtttttta ccgtcccatt tgaccactga ccagtccgct
     8941 ggaaaggccc agagggctga catgcctaat tccgttgcct tttgggcgac aaattcgagc
     9001 ttatctcctt ttggaaagcc catggcaatg gtcacggaaa tgggtaattc gacattatct
     9061 gtcagttctt cgatgatttc aacagactgg ctctggctat ccaccacacg cgccaagcgt
     9121 ttaataccgt cgtcaaatac caaaacaatt tggtcacctg cctgcaagcg catgacagaa
     9181 aacatgtgct tggcagtgtc cttatcgcta atctggaaca tgccctgcgg tgctctgcca
     9241 ttgacaaaat actgctgcat cctagcctcc aatcacacct gagcggtcag ccgtcttctt
     9301 aaagacgcag caattccact cgccctgggt catgtgagtc tcaaggaaga agccagccgc
     9361 ctccgcagat gctcgcacca tgtcccactt atccgcgatg atgccgctca taatcaggta
     9421 gccctcgtcc ttgaccagac ggtaggcgtc ctcggtcaga tggatgagaa tatccgccaa
     9481 gatgttggca acgatgactt ctgctttaat gtcaatgcca cgaagcaaat cgcccgctgc
     9541 gacatgaata ttgctagtat tggcgttgag gtcgatattt tcctgggcta cacgcaccgc
     9601 cacctcatcc aagtcatagg cataaatctc cttggcacct aggagggagc tagcgatgga
     9661 aaggacacct gaacctgtgc cgacatcaat gactgtctcg ccaccacgca agacctgaga
     9721 aagagcaaag aggctcatct tggtcgtcgg gtgggttcct gtaccgaaag ccatgcctgg
     9781 atccaagcgg ataatcttct ccccagctgt cgcctcatag tccgtccaag acggcacaat
     9841 ggtcaaatcg tgggtaatgc gagctggctc atagtatttc ttccagttgt ccgcccagtc
     9901 ttcctctgcc aattcttgac tttctagact gatctgacct gtttccaagc caaagcccgt
     9961 caaatccgcc aagcgagtcg ccaagtctgc cttaacttcc tcaatatcca cagtatcagg
    10021 atagtaagcc gtaatcgcaa tcatatccga ctgctccacc tcgggataga gttcgccgaa
    10081 acagtcttcc tgtcccacat agtcagccga gtcgctaatg gccaccccct gactgcccgt
    10141 ttcaatcatg agatttgaaa ctgcttcttc tgcatcacga tgcacgtgaa tcgttaattc
    10201 ttgccatgag ttcatgtttg ttttcctttt cttttctatc gtcaatcact gtattattgt
    10261 accgatttct agcccatttt acaagttaat attacgcgat ggagccctaa taatactttt
    10321 tcgaaaattt tctaatcgca ctgcgaataa acatgtgtag gaaagtttga aacggtggtt
    10381 ccaagtttct gaacggaggt gatgcccatg aaagtggaca gcaaatctgc tagggcacgc
    10441 actagctcga gttttgaaaa atatcgtttc aaaactctca cgtcggaaat ctctggattt
    10501 atatttatca ggtctgcttg ttgaaaggct gagcttgata atcgtcatca ttttagctat
    10561 tcgagataaa aaataaccgt cagcaaactt tgacacagtt ctgacggtta tttaatctaa
    10621 cgaactgaac caccgtttag cggtcctact gggcgttgag ctggaactca acgccttttc
    10681 tatttttata atagcaaaaa tttcgcctgc agtcaagcaa gagagaaaac agaatgtcaa
    10741 atagaatcta ttaccctcaa ttctataccc actgcaccat actgttctaa ttgttctcgc
    10801 gaataataaa cttccatatc ttctggtttc gcctctctga tactgctttg cgtataccca
    10861 caagacaata aatccagttc tttgtataac tgagcaaaat tatcaaatat gtgaagctct
    10921 aatacttgca cctcgatcgt ttgcgtctga ttttctgtac aataaaaacg gatgcgatct
    10981 ccaatttgta tatgcttgcg cttctcgtca taaagtcgta gctcaatggt cttctgacca
    11041 gacttcatca tttcaaaagg ttttggagcc agtaacattt catgaaccat ctcaatacct
    11101 cggatatggg taaaattccc cttctaccaa gtctgctttg cctttttcaa aagcctctcc
    11161 atcccaagaa atcgcaaatt cttgggcttc tgggtccgcc aaaaagtcca tgagatcatc
    11221 taggccttgg tctgcggtgt ccttgagaaa gcttgcgaaa taggtcagaa attctgctga
    11281 aaagcccttc ttggcgtcaa atggcagagc gaccagatag tcttcctcgt caaagcgaga
    11341 cttgtcctgg ttgtagaaaa ggacatactc ctctaggaaa atatcctcag aagacgcatt
    11401 gccttcgtcg tccaccgttt caatctcagc cgcattttgt gcttccaaga taaaagccaa
    11461 ctcaatagca tgatttttct tgtcccagtt gagctcgtaa tcataagtaa aatgtttgtc
    11521 cagtgccgct tccagcacat ctaaaaagcc atgttttgcc attctatttc ctcttttcta
    11581 taaattccaa taaatttatt tctcgaccgt atttgacgga agcccgctca tctttctcca
    11641 aaatggactt ggttaaatct agttgattta ccgctgctaa ggctacagca tagtgaataa
    11701 catctgctaa ttcttctgcc aaacgagcag agctgtcgtc ttcgctatcc atcatcttgc
    11761 ggcctgcacg ttgattcagt agctctgcta cttcaccgat ttcttccact aatttcataa
    11821 agagactttg ctctggaact gtcgtcccat agtggtcacg caagtattct tccaaaacac
    11881 tcactgtcaa ctccgtcatc ttcgtttctc tccaaatcct aaaattgtag tataatgatt
    11941 ataccataaa tgcactgaaa ggaagcctat gccagccaat ctcgcccttc gtatgcgacc
    12001 caaatccatt gatgaggtaa tcggtcagga acacctggtc ggtcctggaa agattatccg
    12061 tcgcatgatc gatgccaata tgctgtcgtc catgattctc tacggtccgc cagggattgg
    12121 caagacctct atcgcctctg ccattgctgg cacaaccaag tatgcctttc ggacctttaa
    12181 tgccacgacc gacaaccaaa aacgcctgca ggaaatcgct gaagaggcta agttttctgg
    12241 cggtctggtt ctcctgctcg atgaaatcca ccgccttaac aagaccaagc aggatttcct
    12301 gctccctctt ttggaaaatg gcaatatcat catgattgga gcaacgacgg aaaatccatt
    12361 tttctctatt ttacccgcca ttcgcagtcg agtgcagatt tttgaattac aacctttgca
    12421 aaccagccat atccgacagg ccttggagtt ggctttgaca gacagcgaac gtggttttga
    12481 cttccctatt accattgagc ctgaggctct ggattttctg gcaaatgcga ccaacggtga
    12541 ccttcgtgcc gcctacaatt cgctagaact agctgtactt tcgaccaagg aatgtgacga
    12601 cggtagccgc tacattgatc tggacgccgt ggaaaatagc ctgcaaaagt cctacatcag
    12661 catggacaag aacggcgatg cccactacga catcctctcc gccctgcaaa aatccattcg
    12721 gggtagcgat gtcaatgcca gcctccacta cgccgctcgt ttgattgagg ccgaagatct
    12781 gcctagtctg gctcgtcgct tgacggtcat tgcctacgaa gacatcggct tggccaatcc
    12841 agaggctcag attcatacgg tgacggccct tgaagccgcc cagaaaattg gctttccaga
    12901 agcacggatt ttgattgcca atgtggtagt cgatttggct ctttctccca agtccaattc
    12961 tgcctatctg gctatggatg cagctctggc tgatttgcga aagaacggtc atctgcccat
    13021 tccaaatcac ctgcgagacg gtcattatgc tggtagtaag gagctgggaa atgccattgg
    13081 ttaccagtat ccccatgcct atcctgagaa atgggtggac caacaatacc tgcctgataa
    13141 gttacttcat gcggactact tcactgccaa tgacaccggc aaatatgagc gtgccttggg
    13201 catgacacaa gaaaagataa aaaatttgaa aaaaaataga cgccaaaatc cttgatagaa
    13261 ctggtttttt ggcacataca ttttgacacc gcttacattt ttgccatttt tctcttgatt
    13321 tttcaaaaaa aagtggtatt attaaatcat aaataagaac tgctgtggta tacgaattca
    13381 tacctatgtg ttgaccgact atttttgtat tactagggag acaaagatcc tctaacagta
    13441 tgcaagctgg cacacccaga agcaactaag ttagaaacgc gtcacccacc tgcttttagc
    13501 gtgcgggatc aatacaatcc atggataacc ggtaccaata cagcattttt attttttacc
    13561 ttccttagct cagctggcag agcagcggac tcttaatccg tgggtcgtag gttcgatccc
    13621 tacagggagg attggttgat atgaggaaag tcttgattta tcaaggcttt ttctcgtttt
    13681 tttgagtgaa tttggtcaaa atttggtcaa aaagaacctt ttcacattgt gaagggctat
    13741 ttttttaact tatcccacag gacaactcgt ttttcctgta atgatttctg tacatcgatg
    13801 atgcgttgat tcgatgagcc tcgaaattgc agcataagat tgcgcttggt acggtcataa
    13861 cggccgtcaa ctagaatatc taaataggat agtaactcta acttatccgg agtttctaac
    13921 atcatttctt cccatgtgta gcctgtccaa gaccaaatgt ccttttctgg cagttctttc
    13981 cgaattcgct ttacgagtgg gaggaccgtg cccgtgttca gaaaaggctc gccacccaag
    14041 agagttaggc cctgtacata gggctgggcc aagtctgcta aaatgcggtc ttcaagctcc
    14101 ttggtatagg gaatcccagc tttaaaagac caggttgcaa cattgtagca gccctcacag
    14161 tgaaacagac agccactaac atatagagag caacggactc cttctccatc cacaaagtta
    14221 aaggctttgt agtccattat tcgcccttgg ctaagttcct cgctcttcca ttcttgtggt
    14281 ttaggattat tcatttcaaa tacctgagca taagcaaatg aaatctgatc gtttggatga
    14341 attccgtttt accagtacac agactgtttt tatccataaa tggtacttcc aatgctttag
    14401 ctcggattga tcccagcaag cttagtgcgg aaccaatctc aattcctttc ctgttttgat
    14461 tcagcagttt gtcactccca ttaatcctca atccagtatc tttctactcc gtctcgaaca
    14521 tcttccaaaa cgccaccaca agccacaatc gtgcaacggc tggcttgatt gtctgtcaag
    14581 caagtcacaa ggaccttgga aatatttttg gttgcggctt cctgcaaacc aagtcgcagc
    14641 tggtccttgg catagccctt tcctcgctcg gttgggcgaa tggaatatcc gatatgaccg
    14701 cctttattga gcaggaaatc gttgagccgt aggcgtagac tgagaaaacc aagggctcga
    14761 ccagtctggt caaatgacac atattgaatg gaaggaacaa aaccgtctgg cagattgaga
    14821 cctgtctcat agtctttgtt tctaaaaatc cattcttcaa agtcgacatc tttagagata
    14881 aagcctccgt ccatagctga gcctgctttt tcaaattctg ccagcatctc caaaatcgtt
    14941 tccttatccg ctatagtcgg tcttcttaat tccattttag tctccatatt gtcttttgaa
    15001 aaattcactg atgatgtcta tatccagtcc caagtcctgc acaatttctg ccttgtggaa
    15061 atcgtcatag ttgtccttac cgctccaaac aaaagaattg gtcacaatct gatagtcctt
    15121 atctgactcg gctgctctgc cattgaccac aaaaccctca ctgcccggga caatgcccca
    15181 catctgaggg tggagacctg tctgtatact ggagagcaag tctctgccct tgatacgaac
    15241 taagagtact cgcttggaaa agggcaagac cttgaccaag tccgaataaa agattggtcc
    15301 cgccgacaag gaagcccgaa taccgaagcc gttgatgacc gctccatcca cctgcaaacc
    15361 tagttgactc gcctgttcaa ataaagcctg acaaataaca ggggccagag ttgataaccc
    15421 ttgacgaatg ctgtctcgct ctccgtctag tgcctgaggt aaaatcgcta tcggttggga
    15481 aaaaactgcg tcacgttctg atttcatctg gtcgataata gccttgaccg ccctgtcttc
    15541 ttgggtcagt ttctccacct caatcaagtc ataagccagg acctcgtgcc gtccgtctgc
    15601 ataacaccgc agggatagat gaccgataaa tctgccatat tgcccagcct ggcaaatact
    15661 gacgctccct acttgagttg gctctttcaa gattgtatga gtatgcccac ctaaaatcac
    15721 gttgagttca gggaaatcct tggccaaatg cacatcctca tcgtatccta gatgactgag
    15781 taagaccata tgagcctgtg gatccttggc aagaacctga tccaccactc ttcgtagagc
    15841 ttgtttatgg ccttcaaaaa tcacattctc cgacggtgac gcaacctcct gggtttccaa
    15901 ggtagtcaaa ccgaggacat agagggggtt cccattcata tcaaattcaa ggacatcctc
    15961 aagcagcacc aattcatcag ccacctccac atcccgatag cggagattgg aggacacaat
    16021 tggaaactga gcatagtcat ccaagcgact aagcaactca tctccgtggt caaactcatg
    16081 attgcccaag gtcatagcct gacaaccaat ttgattcatc agctcgattt ccttgactcc
    16141 tcggtacata ttgaaaaaga tattacccga aaagagatcg ccgctgtcaa agacaaaggt
    16201 cggaatacct ttttgctcat ttcgagctcg aatatccgca atcagctggg ctttctttgg
    16261 aaaattctcc atgtaggaat gcatatcatt ggtatggaga atactaatat ctgtatagtc
    16321 catactattt tttcttgttt tttgcttgtt tgagcaattc ctgcacacgc gcttttttat
    16381 cctgcttcac attagaattc ttctcatgat agcgtgtcac cagggccttg cccttatcgt
    16441 ctaattgata ttttcccatt cttttcacct cattttcatt tttgaacctg tgttcattta
    16501 taacaaactt ccacagctac ctggaactgt ggaagtccta tcttgtttat ttatgattta
    16561 caaacttgac ccgttcatgt gtttcacacg cgctgagatt tccttgtgac ggccttttac
    16621 catcggacgg gcctgcggat ttcctagata tccacaagtt cgtttaacaa catccaccga
    16681 cttaggatcg ctattcccgc aatttgggca cttgaaacca cgctctgttg gctcaaaatc
    16741 accttcaaaa tcgcaggcgt aacaatggtc aatcggagta ttggttccca agtaaccaac
    16801 acggtcatag gcatagtccc aaacagcttc caaagccttt ggattttgtt gcagtacagg
    16861 gtattcacag taatggataa atccaccact agcacctaca gcaggataaa ttttctcaaa
    16921 atccagtttt tcaaacggtg ttggattttt gcgtacatca tagtggaaac tattagtgta
    16981 atactcttta tccgtaatgt ccttaacgat gccaaatttc tctgtatcca tacggcagaa
    17041 gcggtctgtc aggctttcag atggtgtcga ataaactgaa aaatgataac catattcatc
    17101 cgaccaatct tcaaccaagg ctttcatttt cttgataata tccaccgtga aatcttttgc
    17161 ctctgggttg gtctcccatt cgccaccgta aaatacggtt gcgacttcat acaaaccaat
    17221 gtaccccaaa gatacggttg ctcgacgatt tttaaagact tcatctactg catctgtctt
    17281 agccaaacgt ttgccgaatg ccccatattg atagagaatt ggagcattgg ccggggttgc
    17341 ctccttaacc cgctccacgc ggtaaaccaa ggcatccttg gcaatggcca tacgttctgc
    17401 aaagatttcc caaaacttat ccttatctcc agcagactcc atggcaatcc gtggcaaatt
    17461 gacggttacg acacccaagt tcatccgacc agatgtcaca tcctgtccat tttcatcctt
    17521 ccaaccttga aggaaagagc ggcaacccat tggcaccttg aaggaacctg tcaactcaac
    17581 aatcttgtca taagaaagca tatctggata catacgcttg gttgcacatt caatcgccaa
    17641 ttgcttgatg tcatagtttg gagaatctga ctccaagttc aagccacgct taactgtgaa
    17701 aatcaactta ggaaagatag ctgtccgccc ttcgcgcccc agacccttga tacgaatgtt
    17761 caaaatcgct ttttgaattt ctcgctcaaa ccatgatgtc cctaggccaa aaccgagtga
    17821 ggtgaagggt gtttgtccat tggaagtaaa aagggtgttg atttcatact ccaaagactg
    17881 catagcgtca tagatgtctt tttgcgtttt agcacgcgca tattcttctt gcttgtctgc
    17941 taacacccaa tcctcggcgt ctttcaaatg cttttggtag ttaagttccg catagggcgc
    18001 caaaacttca tcgatacggt cagctgagca gccaccatat tgacttgagg ccacattagc
    18061 aatgatttgt gaaatctgag ccgtagcagt ttgaattgat tttggacttt ctacatcggc
    18121 atttcctatc ttgaagccct gtgccaacat ccctttaaaa tcaatcaaac aacagttggt
    18181 cattggtgta taagggctgt aatccaaatc atggtaatga atatcgcctt tttggtgggc
    18241 attggccaca tgagctggta ataatttgag accgatagac tttccgacaa tacctgctgt
    18301 caggtcccgt tgcgtattga acacatccgc atccttatta gcgttttcat tgaccacaga
    18361 ctggtccttg ctcaacagct tatgaatttc aaaattaata tcggtagcct gatgacggcg
    18421 aaaatcacgg cgtgttcggt attgaatata aagctccgcc aaatcatata aatgagcctt
    18481 taacaattcc tgttcaacga ccgtttgaat ttcgtaaatt tgaacatctt tctcaaatcg
    18541 gcgaccaatt tcagccaaaa cagcttctaa tacaattttt aaacctgcct ctgaaacagg
    18601 atgttctaat tcttggtttg cccgctgaag agcagaaaaa atcttatcct ggtcaaagga
    18661 tactgtccgt ccatcacgtt tcaaaaccaa taattctata ctcggtaaga cattttcttg
    18721 cacattcatc tgacaaacct ccaaaattct tcacttctat tagtgtagca cttcacaaaa
    18781 caaaaatcaa tatcttgtgt aaaaaaatat taaacaacct atccatgtac tatatatagg
    18841 tcttaaaaat tctatcaatt ggaaaacaac tgtgcccaat ttcaccactc gacaaggatg
    18901 aattactaga ttgaaatatg aaaacagatt gggcaaaggt ctaacttctc tatcagaaaa
    18961 cctaaaaaac agccctctaa cagggctggc tctatgtatt gaaaataggc tagggcgggt
    19021 cacccaccaa tgtcattaag ttaactaacc tatcacgttt tgtggtaggt tagttttttc
    19081 tatggtacac taaaaataaa aggggaaaag tcatgttaga tcagattaaa gctcacttac
    19141 ttgatagtat taacgacatc gtttccatcg caaaccagtt tgtgcttcat cctgaaaaag
    19201 attttagtcg gaaaagtcag ctaactatgg aaaccatgat tcaagctata ctgaccatgg
    19261 gtggtaatac cttagccaaa gagctacttg atttagattt gcccgtctct caatctgcct
    19321 ttgtccaacg acggtatcag cttaaacatc aagcttttaa agccctgttt gccaatatta
    19381 cttctaagat tccaacattt aaagatctcc ctatcttggc tgttgatggt agtgatgtgg
    19441 ttctaccaag aaatcgttct gataaaacaa ccacgttcca aactggacca caccacactc
    19501 cttacactct cattcatatc aatgctcttt acaatcttga acaagagatt tatcatgacc
    19561 ttcgaattca gaataatcgg gaggttgatg agcgtgcggc tttcatcgac atgatggaga
    19621 gttgcccttt tgaacaagct ctggtgataa tggatagggg gtatgaatcc tacaatgtca
    19681 tggctcactg ccaagaaaga aattggtcct atattattcg tattcgtgac gggaatcatt
    19741 ctatgaaatc aggatttaac ctccctgaca ccccttgttt tgatgaagag tttgacctaa
    19801 acatctgtca caaacaaacc aatgtcatga aagaactgta tcgagacttc cctaatcagt
    19861 atcatttttt acctcataat gcttcctttg accttttacc aaactctagt cgaaaaagtg
    19921 atccaatcag tttttatgac cttcattttc ggatggtgcg tctcgaaatc aagccaggtt
    19981 tctttgagac tttggtgaca aatacggatt attcaccaga aaaattaaaa gatctctatg
    20041 cctacagatg gggcatagag actagttttc gtgacctaaa atacagtatc ggtctgactc
    20101 attttcatgc aaaaaagaag gaagggattc tccaagaaat ctacgctcac tttatcaatt
    20161 ttaatgtttg taaatggcta acctcacacg ttgctattaa accatcaaag ttaaaacagg
    20221 cttataaaat ttgtttttca gacgctgttt atgcctgtcg aaaatttctt agagaagaac
    20281 tcacttcctt ccaattagaa acctacattg ctaagcattt
//
LOCUS       DBNFCO010000038        19270 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.038, whole genome shotgun sequence.
ACCESSION   DBNFCO010000038 DBNFCO010000000
VERSION     DBNFCO010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 19270)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19270)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19270
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.038"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            17..691
                     /locus_tag="AC1PIV_001116"
     CDS             17..691
                     /locus_tag="AC1PIV_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HIP6612142.1"
                     /translation="MSEQFIPSVLSDLRQDIVQMPEVIKECSGIRIYGRRIRSVLFTT
                     DVSIIANHNADAILAVYPFTPSPAIIKSIMLVASVPVLAGVGGGLTTGMRSANMSLLS
                     ESEGAYAVVVNGPTDVKTIEAINKVVDIPIIYTVVSEKSDLTSRIKAGVDILNVSCGM
                     ETPRVVKKIREAFPDFPIIATGGPTEDSIRRVIEAGANAVSYTAPSNGELFKGKMEKY
                     RKHAKD"
     gene            908..1210
                     /gene="gatC"
                     /locus_tag="AC1PIV_001117"
     CDS             908..1210
                     /gene="gatC"
                     /locus_tag="AC1PIV_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA];
                     GO_process: GO:0006450 - regulation of translational
                     fidelity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HIP6612143.1"
                     /translation="MKISEAEVRHVAKLSKLEFSDQETAEFATSLSKIVDMVELLNEV
                     DTTGVAVTTTMADRKNVLRADIAQKGESREELFKNVPESQDNFIKVPAILDGGGDA"
     gene            1210..2676
                     /gene="gatA"
                     /locus_tag="AC1PIV_001118"
     CDS             1210..2676
                     /gene="gatA"
                     /locus_tag="AC1PIV_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HIP6612144.1"
                     /translation="MTFNNKTIDELHDLLVKKEISAVELTKATLEDIKSREGAVDAFL
                     TITEDAALAQAAALDEKGIDADNVMAGIPLAVKDNISTKGILTTAASKMLYNYEPIFD
                     ATSVAQAYAKDMIIVGKTNMDEFAMGGSNENSAFKPTKNAWDQTKVPGGSSGGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGMKPTYGTVSRFGLIAFGSSLDQIGPFSQTV
                     KENAQLLNVISGHDVKDATSTINEIADFTSKIGQDIKGMKIALPKEYMGEGIDPQVKE
                     TILKAAKHLESLGAIIEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGFRAEDA
                     TNLDEIYVKTRSQGFGEEVKRRIMLGTFSLSSGYYDAYFKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPTVAFGLDTLNHDPVAMYLADLLTIPVNLAGLPGLSIPAGFVEGLPVG
                     LQLIGPKYSEETIYQVAAAFEATTDYHKQQPVIFGGAN"
     gene            2676..4115
                     /gene="gatB"
                     /locus_tag="AC1PIV_001119"
     CDS             2676..4115
                     /gene="gatB"
                     /locus_tag="AC1PIV_001119"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017770317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HIP6612145.1"
                     /translation="MNFETIIGLEVHVELNTNSKIFSPSSAHFGEDPNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKDMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEIELEDGSTKKIRIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEIIQYTGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FNYVRKGLQHEVERQAKILRSGGQIQQETRRYDESTGETILMRVKEGSADYRYFPEPD
                     LPLYEIDDSWIEEVRAELPVFPKARRAHYVENLGLTAYDAGQLTSTKALSDFFEAAVA
                     AGGDAKQVSNWLQGEVAQFLNAEGKTIEQIALTPENLVEMIALIADGTISSKIAKKVF
                     VHLAKEGGSAKAYVEKAGLVQISDPAVLIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVAQQLLAQELAKLLD"
     gene            4236..5585
                     /locus_tag="AC1PIV_001120"
     CDS             4236..5585
                     /locus_tag="AC1PIV_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyguanosinetriphosphate triphosphohydrolase
                     family protein"
                     /protein_id="HIP6612146.1"
                     /translation="MSKDFDDFLREHEENVNKLKKRDKETESDKERARDEFSRDYSRV
                     IYSNSFRRQQGKMQLFAVNGRAFHRNRLTHSFEVAQIARGIVDYLKKNTSNNIDIDFN
                     SMSVVVETGALVHDIGNPPFGHHGERILNDLAKDIGFEGNAQGLRVLKNIEKKSPDHK
                     GLNLTYRTLASILKYYVPYRKSRKTEKFIYKEDYEEFKKRFKEMDVFVRTIDVQIVDL
                     ADEIAYCAHDLEDALASNYFTIDQFVFLLEQKLGEDQTLEDFKEWIEEAKNKAKRSKS
                     NDDYDFYFRRELLSIIVNKFIEDIDIVELNEKDKKKLGTDQDQELGLGHYKKLAGALK
                     KTIFEGVTNSDDIILYENVGTKVLTRLFALFMNEEYNRESFLMPIEYRFEKDDTQSDK
                     KRKVLDYISGMMDTYAIEMYIKHFGTDPFLEKYDAAIFKKGTGKKLIECLAQNFLHK"
     gene            complement(5644..6642)
                     /locus_tag="AC1PIV_001121"
     CDS             complement(5644..6642)
                     /locus_tag="AC1PIV_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HIP6612147.1"
                     /translation="MVTIKDIAKQAHLSSATVSRVLKGDLTLSVSQETRDRIFNLAQE
                     LGYTKHIKKQAPQQKGTIGIVQWYTESEELADLYYYSIRASIEHTASLLGYQIVRSFN
                     DLTNPLLQEVDGIIAVGKFSSGQIAELSSLSSKIIFVDSDTLTEGFSCVTTDFEHSVQ
                     TVIDHFHSQGLTDIGLLVGQEETTDGHQLPTDPRLTAFRDYLDTLGMLQEDYIYQGKF
                     STQSGYELMSQAIEDLGDKLPPAFFMANDTLAVGALRALQERQIAVPDRIQLITFNDT
                     AITRQVYPALSSISVFTEEMGQEAMQLLDRIITSPTPHHPRKIKLGTQLVIRESSY"
     gene            6776..7948
                     /locus_tag="AC1PIV_001122"
     CDS             6776..7948
                     /locus_tag="AC1PIV_001122"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004335 - galactokinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0046835 - carbohydrate phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HIP6612148.1"
                     /translation="MNTEQLKQAFLDVFGQEADATFFSPGRINLIGEHTDYNGGHVFP
                     AAITLGTYGAARKRDDQVLRFYSANFEELGIIEVDLNNLVFDKADNWTNYAKGVLKFL
                     KEAGHVIDTGMEVFVYGNIPNGSGLSSSASLELLIGIIAEELYGLELTRLDLVKIGKQ
                     TENHFIGVNSGIMDQFAIGMGADNRAIYLDTNSLEYELVPLDLGDHVIVIMNTNKRRE
                     LADSKYNERRAECEKAVEELNAVLNIQTLGELDEWTFDQYSYLIKDENRIKRARHAVL
                     ENQRTLQARKALEEGDLATFGRLVNASHVSLEHDYEVTGLELDTLAHTAWEQEGVLGA
                     RMTGAGFGGCGIAIVHKDKVEAFKENVGKTYTEVVGYAPSFYVAEIAGGSRVLSRK"
     gene            7958..9439
                     /gene="galT"
                     /locus_tag="AC1PIV_001123"
     CDS             7958..9439
                     /gene="galT"
                     /locus_tag="AC1PIV_001123"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0017103 - UTP:galactose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019388 - galactose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HIP6612149.1"
                     /translation="MMTGLVDRFVEQVIANSDFEEMDAIYLRNRVLALVGDQVLTVQT
                     DLEDLIELKDELLAHGVRTGFVGELLEEQDMVGSCLMDLMTPSPSQVNRDFWQTYQDS
                     PEQAISDFYELSKRNDYIKMAAIAKNIYYPVSTEYGDLEITINLSKPEKDPKSIAAAT
                     KAEASNYPKCLLCMENEGYQGRINHPARANHRIIRLELGQEKWGFQYSPYAYYNEHAI
                     FLNQEHVPMVISPRTFEQLLDLLDLLPGYFVGSNSDLPISGGSILTHNHYQGGRHSFA
                     MDQAPIEHQLVFEGFESVSAGIVKWPMSVIRLSSADKPSLLGLAAKILEKWRSYSDDS
                     VQIKAETDGTPHHTITPIARKRGDLYELDLVLRDNQTSEEFPDGIYHPHPDVQHIKKE
                     NIGLIEVMGLAILPPRLKAELAEVEKFLLGQDSQVADYHQPWAESLKTAHPDVTEETV
                     EQVVRESVGQIFARVLEDAGVYKRTPEGQAAFLRFVEFVGLAT"
     gene            9515..10423
                     /locus_tag="AC1PIV_001124"
     CDS             9515..10423
                     /locus_tag="AC1PIV_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012774971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HIP6612150.1"
                     /translation="MAEKRLGTLITVIAGIAWGLSGVSGQYLMSRGVSVDMITSLRLL
                     VSGLFLVGLAYATAKEQLLAVLKDKNALLGIFIFAMLGLVLNQTAYLQAIYHTNAGTA
                     TVLQYLCPILVLAYTCLKNREKPSGIELISIILAIAGTFLIATHGKLDELAVTPIGLF
                     WGIFSAFTYALYIILPGKLIRQYGSITVIGLGMLMGGFVVTLGLQTWQHRLPIDGGSF
                     LGLLGIVGVGTIFAYTAFLKGVSMVGPVNGSLLASIEPIASVFFAVWLVNEQFYAIDF
                     VGMLLILLAVLLISLKDILVAQKSIG"
     gene            10471..11100
                     /locus_tag="AC1PIV_001125"
     CDS             10471..11100
                     /locus_tag="AC1PIV_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012774972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HIP6612151.1"
                     /translation="MIKEFCSENHVGVMKALSLGAKRIELCDNLAVGGTTPSYGVVKH
                     VCQLAHENEATVMTMIRPRGGDFCYDKAEVEMMVEDCKAAIELGADGLVYGLLTEENW
                     LDEPALERLFAVSQDCQIVFHMAFDQIPRERQFEALDWLVEHGVTRILMRGSLTGSAL
                     NNVEWLQEIVAYAQGKIEILIGGGLTVDNVPTLLEALPINQVHGTRLFW"
     gene            11307..11681
                     /locus_tag="AC1PIV_001126"
     CDS             11307..11681
                     /locus_tag="AC1PIV_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612152.1"
                     /translation="MNPLRKELRTVAVEVSDLALDYAVRLAQSLNSTLRYHNYDSLIA
                     IAKTKGVEPKGKDCQSFSEYRQRYSLYDAKKLIYRALAWRLFDDSHADYGHALTILGL
                     DEDESGVEQIGFAFSKFTLDID"
     gene            11865..12392
                     /locus_tag="AC1PIV_001127"
     CDS             11865..12392
                     /locus_tag="AC1PIV_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HIP6612153.1"
                     /translation="MSLENYMPDFALEKAYDVTVESLKKHGIKVVFVDLDNTLIAWNN
                     PDGTPEMRQWLHDLQDAGIPVVVVSNNKYERVKRAVEKFGIEFEAFALKPFTFGINRA
                     LKRFDVQPYEVIMIGDQLMTDIRAAKRAGLKSVLVKPLIKTDSINTQINRWRERRTMK
                     KIIAKYGAIDYKREM"
     gene            12393..13499
                     /gene="yqeH"
                     /locus_tag="AC1PIV_001128"
     CDS             12393..13499
                     /gene="yqeH"
                     /locus_tag="AC1PIV_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HIP6612154.1"
                     /translation="MEELFCIGCGAQIQTLDKAVAGFTPQSALEKGLETGQLYCQRCF
                     RLRHYNEISDVNISDDDFLKLLHSVGESDALVVNVIDIFDFNGSVIPGLPRFISGNDV
                     LLVGNKQDILPKSVKTGKVTQWLTERAHEIGMRPVDVVLTSAQNKQAIKDLIEKIEQH
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDKDVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYISPRKEIKPKTYQLNPEQTLFLAGLGRFDFVAGERQ
                     GFTAFFDNELQLHRTKLQGASEFYQKHAGSLLVPPTSKELKEFPELVRHEFTINEKTD
                     VVFSGLGWIRVNEKAKIAAWAPKGVDVVIRKAII"
     gene            13769..14080
                     /gene="yhbY"
                     /locus_tag="AC1PIV_001129"
     CDS             13769..14080
                     /gene="yhbY"
                     /locus_tag="AC1PIV_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HIP6612155.1"
                     /translation="MMLTSKQRAFLNSQAHSLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKQVKE
                     I"
     gene            14093..14725
                     /locus_tag="AC1PIV_001130"
     CDS             14093..14725
                     /locus_tag="AC1PIV_001130"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HIP6612156.1"
                     /translation="MAIELLTPFTKVELEVEKKETNRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLKLDQVLLMPEFIPPHVDKKETIDEYHRYSMLKMAIAGIEGLGIETIELERR
                     GVSYTYDTMKLLKEKNPDTDYYFIIGADMVDYLPKWHRIDELVQLVQFVGVQRPRYKA
                     GTSYPVIWVDVPLMDISSSMVRSFIKQGRVPNFMVPHEVLDYIEEKGLYQ"
     gene            14722..15309
                     /gene="yqeK"
                     /locus_tag="AC1PIV_001131"
     CDS             14722..15309
                     /gene="yqeK"
                     /locus_tag="AC1PIV_001131"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HIP6612157.1"
                     /translation="MIAADLTFDRQALLEKIRVAMKPARFQHVLGVEQAALVLADQYG
                     CDPKKASLAALLHDYAKEVEDQVFLDLIAKYDLDKDLLNWDNNIWHGVVGAYKIAEDF
                     GLEDEEIFQAIQRHTVGAGQMTLLDKVLYVADYIEPNRDFPGVDEARRIAKESLDKAV
                     AYETAQTISYLAKKGIPIYPQILETYNGYVVWLKE"
     gene            15840..16142
                     /locus_tag="AC1PIV_001132"
     CDS             15840..16142
                     /locus_tag="AC1PIV_001132"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIP6612158.1"
                     /translation="MWADEQVVGFALIDIDEDIQQYMLWRFMIGQEFQGRGYGQAALE
                     VVIAMAQSHPVCDHLIAAYVKGNQKMAHLLEKNNFVLDSEEERELVFRLETPGVQL"
     gene            16139..16649
                     /locus_tag="AC1PIV_001133"
                     /pseudo
     CDS             16139..16649
                     /locus_tag="AC1PIV_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935141.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
     gene            16651..17010
                     /gene="rsfS"
                     /locus_tag="AC1PIV_001134"
     CDS             16651..17010
                     /gene="rsfS"
                     /locus_tag="AC1PIV_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HIP6612159.1"
                     /translation="MKELDLVKVVVQAADDKRAEDLVVIDVQGVTSLTDYFVIASSMN
                     SRQLEAIAENIREKVADVGIKSSRVEGDSNGGWVLLDLGGVVVHIFSEEMRDLYNLEK
                     LWHEGSFLEVADFLEEE"
     gene            17312..18055
                     /locus_tag="AC1PIV_001135"
     CDS             17312..18055
                     /locus_tag="AC1PIV_001135"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent DNA methyltransferase"
                     /protein_id="HIP6612160.1"
                     /translation="MATYETFAAVYDEIMDDSLYDKWTDFSLRNLPQDTKTILELACG
                     TGIQAVRFAQKGYEVTGLDLSYEMLELAQKKAEAAGVMMELAQADMMALEGVGDFDAV
                     TCYSDSLCYMSDREAVLRVFEGVHSVLNQGGTFLFDVHSIYQMEEVFAGYSYHENYED
                     FAFVWDTYEGEHAHSIVHELTFFVKDEASQEERFIRRDEVHEERTYPIETYVELLKEA
                     GFASVEVFADFEDEAPTETSQRWFFKCKK"
     gene            18150..>19270
                     /locus_tag="AC1PIV_001136"
     CDS             18150..>19270
                     /locus_tag="AC1PIV_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012774973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612161.1"
                     /translation="MESLHRKISNWGQKIFLQFKNRTPNVEGISFNRLTSNKNIDLER
                     ENPSFKQALDFAIQDDELKNVAITGNYGSGKSSLLDSYEAKYSNKKFLHISLADYKEN
                     DLSGYKENDSSESGKKLNVRQINVIEGKIINQLLHQIHPKHVKKSIFKTLSRTPRRIP
                     LLLTVYIVLFFITLSYFLKPNFLKALVTADKVFGWDANTVFSWLFLILLFIGSLTTIW
                     YIVENKTIKSLTIGGKNVSSEIDIFSDQSMRVSYFDKYLDDVLYLLNESRADVIVFED
                     IDRFENNTIFAKIKELNVLVNNKRKIAKKSSKLVFLYLIRDDLFISKERTKFFDFIIP
                     VLPVITSSNSSDKLTTTLKEMGIKSGLADDFLFRISLYI"
BASE COUNT         5533 a         3491 c         4697 g         5549 t
ORIGIN      
        1 atagaggagg ttgcggatga gcgaacagtt tattccatct gttttatcag atttacggca
       61 agatattgtt cagatgccag aagttatcaa ggaatgtagt ggaattcgta tttatggtcg
      121 tcgcattcgt tcagtcttat ttacaacgga tgtgtctatt attgctaatc acaatgcaga
      181 tgctattttg gctgtttatc catttacgcc cagtccagct attatcaaaa gtattatgtt
      241 ggttgcgtca gttccagtct tggctggtgt tggtggaggc ttgacgacag gtatgcgttc
      301 agctaatatg agtctcttgt ctgagtcgga gggagcatac gctgttgtgg taaatggacc
      361 aacggatgta aaaacaattg aggcaatcaa taaagtagta gatattccta tcatttatac
      421 cgttgtttct gaaaagtctg atttaacctc acggattaaa gctggagtag atattttaaa
      481 tgtttcttgc ggtatggaaa cgccaagggt tgtgaagaag attcgagaag ctttccctga
      541 ctttccaatt attgcgactg gtggtccgac tgaggactct attcgtcggg ttatcgaagc
      601 tggagccaat gctgtctcct atacagcacc aagtaatggg gagcttttta aagggaaaat
      661 ggaaaaatac cgcaaacatg caaaggatta gctcataaaa agataggcta agcaaacagt
      721 aagttttatt gctagatgaa acttgctgtt ttttatcgtt ttacggtgtg agattaggaa
      781 tacttcgcaa tttaaagaat ggatttttag gaggaaatag gtaacatatt aggtcatttc
      841 tacctttgtc tgaggctgga aatatggtat aatgagaaga tagatttcca ttaggaggaa
      901 agtaagaatg aagatttctg aagctgaagt ccgtcacgtt gccaagctgt ctaagctgga
      961 attttcggac caggaaacag cggaatttgc gacaagtttg agcaagattg tcgatatggt
     1021 tgaattgctc aatgaagtag atacgacagg tgttgcggta acgaccacta tggctgaccg
     1081 taagaatgtc ttgcgagcag atattgccca aaaaggtgag agccgtgagg agctctttaa
     1141 aaatgtgcct gaatcacaag ataactttat caaggtacca gctattctag acgggggagg
     1201 agatgcctaa tgacttttaa caataaaacc attgatgaat tgcatgacct ccttgtcaaa
     1261 aaggagattt ctgcggttga gttgaccaag gcaactttgg aagacatcaa aagccgtgag
     1321 ggagcagtgg atgctttctt gactatcaca gaagatgcgg ccttggcgca ggctgctgcc
     1381 cttgatgaaa aagggattga tgcggacaat gttatggcag ggattccttt ggcagtcaag
     1441 gacaatatct ctactaaggg gattttgacc acggcagctt caaaaatgct ttataactac
     1501 gagccgattt tcgatgcgac atcagttgct caggcctacg caaaggatat gattattgtc
     1561 ggtaagacaa acatggatga gtttgccatg ggtggttcta atgagaactc tgccttcaaa
     1621 ccgactaaaa atgcttggga ccagacaaaa gttcctggtg gttcttcagg tggctcagct
     1681 gctgctgttg catctggtca ggtccgtttg tcactcggtt ctgacacagg tggttccatt
     1741 cgtcaaccag cagcctttaa tggtatcgtc ggtatgaaac cgacctacgg aacggtgtca
     1801 cgttttggtc tgattgcctt tggttcatct cttgaccaga ttggtccatt ctcacagaca
     1861 gttaaggaaa atgcccagtt gctcaatgtc atctctggtc atgatgtcaa ggatgcaaca
     1921 tcaacgatca atgaaattgc agacttcact agcaagattg gtcaggacat caagggcatg
     1981 aaaatcgctc ttccaaaaga atacatgggc gaagggattg atccgcaggt caaggaaact
     2041 attctcaagg cggctaagca cttggaaagc ttgggagcaa tcattgaaga agttagtctg
     2101 ccacattcta agtatggggt tgctgtttac tatattatcg catcatcaga ggcgtcttct
     2161 aacttgcagc gttttgacgg tatccgctat ggtttccgtg cagaagatgc gaccaacttg
     2221 gatgagattt atgtgaaaac ccgtagccaa ggttttggtg aggaagtcaa acgtcgtatt
     2281 atgttaggta catttagctt gtcatctggt tactacgatg cctacttcaa gaaggctggt
     2341 caggtgcgga ccttgattat ccaagatttt gaaaaggtct ttgcggacta tgacttgatt
     2401 ttggggccaa ctgctccgac ggttgccttt ggtttggaca cgctcaacca tgaccctgtg
     2461 gccatgtact tggcggactt gttaacaatt cctgtaaact tggcaggtct tcctggtctt
     2521 tctattcctg ctggttttgt agaaggcttg ccagttggtt tgcagttgat tggtccaaaa
     2581 tactcagaag agaccattta ccaagtagct gctgcctttg aagcgacgac agactaccac
     2641 aagcaacaac cagtgatttt tggaggtgct aactaatgaa ctttgaaacg attattggtc
     2701 tagaagtcca tgtggagttg aataccaact cgaaaatttt ctcaccttca tctgcgcatt
     2761 ttggtgagga tccaaatgcc aataccaacg tgattgactg gtctttccct ggcgtccttc
     2821 ctgttcttaa taagggtgtt gtggatgctg gtattaaggc tgccttggct ttgaacatgg
     2881 acattcacaa ggacatgcac tttgaccgca agaactattt ctatcctgat aaccctaaag
     2941 cctatcagat ttctcagttt gacgagccga ttggctacaa tggctggatt gagattgagc
     3001 tagaagatgg ttcaaccaag aaaatccgta tcgagcgtgc gcacttggaa gaggatgcag
     3061 gtaagaatac ccatgggaca gacggctatt cttatgtgga cctcaaccgt cagggcgtgc
     3121 cattgattga gattgtatca gaagcggata tgcgttcgcc tgaggaggcc tatgcctact
     3181 tgacagccct taaagaaatc attcagtaca ctggtatttc agatgtgaag atggaagagg
     3241 gttctatgcg cgtggatgcc aacatctctc ttcgtcctta tggtcaggag aaattcggta
     3301 ccaagactga gttgaaaaac ctcaactcct tcaactatgt gcgcaagggc ttgcagcatg
     3361 aagtagaacg tcaggcgaaa atcttgcgtt caggtggtca aatccagcag gaaactcgtc
     3421 gttacgatga atctactggt gaaaccattc tcatgcgtgt caaggagggt tcagctgact
     3481 accgttactt ccctgagcca gacctgccac tctatgagat tgatgatagc tggattgagg
     3541 aagttcgtgc agaattgcca gtctttccaa aggctcgccg tgctcactat gtagaaaact
     3601 tgggcttgac cgcctatgat gcaggtcaat tgacgtctac caaggccttg tctgacttct
     3661 ttgaagcagc ggtggcagca ggtggcgatg ccaaacaagt ttctaactgg ttgcagggtg
     3721 aagtggctca gttcctcaat gctgaaggta agactattga gcaaatcgcc ttaacaccag
     3781 aaaacttggt tgagatgatt gccttgattg cggatggaac catttcatct aaaatcgcca
     3841 agaaagtctt tgttcacttg gccaaagaag gtggctctgc taaggcttat gttgagaagg
     3901 ctggtttggt gcagatttca gacccagcag tcctcattcc gattatccac caagtctttg
     3961 cggataacga agcggctgta gctgacttca agtctggcaa acgcaatgca gacaaggctt
     4021 ttacaggttt cttgatgaaa gcaaccaagg gacaagccaa tccacaagtt gcacaacaac
     4081 tcttggctca ggaattggct aagttgttgg attagtttta aaactataga aactatagaa
     4141 tacaaaaatc actcaaaaag agtggttttt tgttgactaa aataataatt attattatca
     4201 tcatgatata aaggtatgag ggggaataaa tagatatgtc aaaagacttc gatgattttt
     4261 tacgagaaca tgaggagaat gtcaataagt taaagaaacg tgataaggaa actgagtcgg
     4321 ataaggaaag agcaagagat gaattttcta gagattattc cagggtaatc tattctaatt
     4381 cctttagacg gcaacaaggg aaaatgcaac tgtttgccgt taatggtaga gcttttcaca
     4441 ggaacaggct gacacatagt tttgaagtgg cacagattgc aagggggatt gttgattatt
     4501 tgaaaaaaaa tacatctaat aatattgata tagatttcaa ttcgatgtct gtcgttgttg
     4561 aaactggtgc acttgtacac gacattggca atcccccatt tggtcatcat ggagaaagaa
     4621 ttttaaatga tttggcaaag gatattggtt ttgaaggaaa tgcccaaggg ttacgggtat
     4681 taaaaaatat tgaaaaaaag tctccagatc ataaaggctt aaacttaaca tatagaaccc
     4741 tagcttcaat tctaaaatat tatgttccat atagaaaatc acgaaagact gagaagttca
     4801 tatacaaaga agattatgag gaatttaaaa agagatttaa agaaatggat gtgtttgtga
     4861 gaacaattga tgttcaaatt gttgatttgg cagatgaaat tgcttattgt gcacatgact
     4921 tggaagatgc attggcgagt aactacttca ccattgatca atttgtattt ttgttggaac
     4981 agaaattggg agaagatcaa acattagagg attttaagga atggattgaa gaggcaaaaa
     5041 ataaggcaaa aagaagtaaa tccaatgatg attatgattt ttattttaga cgagaattgc
     5101 tttctattat tgtgaataaa ttcattgagg atatagacat tgtagaactt aatgaaaaag
     5161 acaagaaaaa attaggaact gatcaggatc aagaactagg gctcggtcat tataaaaaac
     5221 ttgctggtgc attgaagaaa acaattttcg aaggcgtaac aaattctgac gatattattt
     5281 tatatgaaaa tgttgggacg aaagtgttga ctagattatt tgctttattc atgaatgaag
     5341 aatataatcg ggagagtttt ttgatgccga tcgaatatcg atttgaaaaa gacgataccc
     5401 aaagtgacaa gaaaagaaaa gtactagatt atatttctgg catgatggac acttacgcaa
     5461 ttgagatgta tataaaacat tttggtacag atccgttctt agagaaatat gatgcagcta
     5521 tattcaagaa aggaactggt aaaaagctaa tagaatgttt agcacaaaat ttcttacata
     5581 aatagccata tgtttaagaa aaccgagagt tcgtgttgaa ttctcgggtt ttcttatgca
     5641 cttttagtaa gaactctcgc gtattaccag ctgggtaccc aacttaatct tacgggggtg
     5701 gtggggcgtt ggacttgtta tgatacggtc cagtagctgc atagcttcct ggcccatttc
     5761 ctcagtgaag acgctgatgg aagacagggc tggatagact tggcgcgtga tggctgtatc
     5821 gttaaaggtg atgagttgga ttctatctgg cactgcgatt tgacgttctt gtaaagcacg
     5881 cagggcaccg acagccagag tatcgtttgc catgaaaaag gcagggggta gcttgtcgcc
     5941 taggtcctca atagcctggc tcatcagctc atatcccgac tgggtggaga attttccttg
     6001 atagatgtag tcttcttgga gcatgcccaa ggtgtctagg tagtcacgaa aggcagtcag
     6061 gcgggggtct gttggcagtt ggtgtccatc tgtggtttct tcctgtccga ctaggagtcc
     6121 aatatcagtc agaccttgtg aatggaagtg gtcgataact gtctgaacag agtgttcaaa
     6181 gtcagttgtg acgcaggaga atccctcggt cagcgtatca gagtccacaa aaatgatttt
     6241 agaagacagg ctagatagct ctgctatttg tccagaagaa aatttgccaa ctgcgatgat
     6301 gccgtccact tcttggagga ggggattggt caggtcgttg aaggagcgga cgatttggta
     6361 gccgagtaag ctggcggtat gctcaatact ggcccgaatg gagtagtagt agaggtcggc
     6421 cagctcttcg ctctcggtgt accactgaac aataccgatg gtgccttttt gttgaggtgc
     6481 ttgttttttg atgtgcttgg tgtagcccaa ttcctgtgcc aagttgaaaa tgcggtcgcg
     6541 ggtttcttgg ctgacggata gggtcaggtc tcccttgaga acgcgggaaa cggtggcaga
     6601 ggaaaggtgg gcttgttttg ctatgtcttt gattgtaacc atgttcttct cctgtttatt
     6661 tgtctctagt atagcataaa aaaacaaaat tagtaaaaat ttagtaaaaa tattgacttt
     6721 taaattgttg agttgtacaa taaaagaaaa cgattacaaa atctaggagg ttcttatgaa
     6781 cacagaacaa ctcaagcagg cctttctcga tgtgtttggt caagaggcag atgcgacttt
     6841 cttctcacca ggtcggatta atttgattgg tgagcacacg gactacaatg gtggtcatgt
     6901 ctttccagcg gctattacct tggggaccta cggggctgct cgcaaacgtg atgaccaagt
     6961 tttgcgtttc tattccgcaa actttgaaga acttggaatt atcgaagtgg atttgaacaa
     7021 tctggtcttt gataaggcgg ataactggac caactatgcc aagggggttc tcaaattctt
     7081 gaaagaagca gggcatgtca ttgatacagg gatggaagtc tttgtttacg gtaacattcc
     7141 aaacggttca ggcttgtcat catcagcttc cttggaactc ttgattggca ttatcgcaga
     7201 agagttgtat ggacttgaat tgactcgact tgatttggtg aaaattggga aacaaacgga
     7261 aaatcacttt attggtgtca attctgggat catggaccag tttgcgatcg gtatgggagc
     7321 agataatcgg gcgatttatc tagataccaa tagcttggag tatgaattgg taccgctaga
     7381 tttgggtgac catgtgattg tgatcatgaa caccaacaaa cgccgtgaat tggcagattc
     7441 taagtacaat gaacgtcgcg cagaatgtga aaaagcagtg gaagaattga atgctgtcct
     7501 gaacattcaa actctgggag aattggatga atggaccttt gatcaatata gttatttgat
     7561 taaggatgaa aatcgtatca agcgtgcccg ccatgctgtt ttggaaaatc aacggacctt
     7621 gcaggctcgt aaggccttgg aagaaggaga tttggctacc tttggtcgtc tggtcaatgc
     7681 ttcccatgtt tccttggaac atgattatga agtgacaggt ttggaattgg ataccttggc
     7741 tcacacagct tgggagcaag aaggagttct tggtgctcgg atgacaggag ctggcttcgg
     7801 tggctgtggt attgccattg tccacaagga taaggtggaa gccttcaaag aaaatgtcgg
     7861 caagacctat acagaggttg tgggctatgc accaagcttc tatgtagcgg agattgctgg
     7921 aggctctcgc gttttatctc gaaaatagat tggagaaatg atgacaggat tggtggatcg
     7981 ttttgttgag caggttattg ccaacagtga ttttgaggaa atggatgcta tctacctgcg
     8041 aaatcgggtc ttggctttgg tgggagacca ggttctgact gttcaaacag atttagagga
     8101 cttgattgaa ttaaaagatg aactattggc acatggagtt cgaactggtt ttgtgggtga
     8161 attgctggaa gagcaggaca tggttgggtc ttgtttgatg gatttgatga caccgagtcc
     8221 gagtcaggtc aatcgtgatt tttggcagac ctatcaggat agtccagagc aagcgattag
     8281 tgacttttat gaattgagca aacgtaatga ctatatcaag atggctgcga ttgcgaaaaa
     8341 tatctattat ccagtttcga cagagtatgg ggatttggaa atcacgatca atctgtccaa
     8401 acctgagaag gatcccaagt ctattgcagc tgctacgaaa gctgaagcaa gcaattatcc
     8461 caaatgccta ctctgcatgg aaaatgaggg ctatcaggga cggattaatc atcctgcacg
     8521 cgccaaccac cgcattattc gcttggagct tggacaggaa aagtggggct tccagtattc
     8581 gccctatgct tactacaatg aacatgctat tttcctaaat caggaacatg tgccgatggt
     8641 tattagtccg cgaacttttg agcagctctt ggacttgttg gatttgttgc caggttattt
     8701 tgtcggttcc aactctgacc tccctatctc gggtggctct atcttgaccc acaatcacta
     8761 tcagggtggg cggcacagtt ttgccatgga tcaggcgccg atagaacacc agctggtctt
     8821 cgaaggcttt gagtcagttt cggctggcat tgtcaaatgg cccatgtcgg tgattcgctt
     8881 gagttcagca gacaaaccgt cgcttcttgg tttagcggct aagattttgg aaaaatggcg
     8941 gagctactca gatgatagcg ttcagattaa ggctgagaca gatggaacac cccatcatac
     9001 gattacccca attgctcgga aacgaggcga tttgtacgag ctggatttgg ttctccgcga
     9061 taatcaaact tcagaagagt ttccagatgg catctatcat ccacatccag atgtgcaaca
     9121 tatcaagaaa gaaaatatcg gcttgattga ggtaatgggc ttggcgattt tacccccacg
     9181 cttgaaggca gaattggctg aagtagaaaa attcttactg ggtcaagata gtcaggtggc
     9241 tgactatcat cagccttggg cggaaagcct gaaaacagct cacccagatg tgacggaaga
     9301 aactgtcgaa caagtagttc gtgagtcagt gggacaaatc tttgcgcgtg tattggaaga
     9361 tgcaggggtc tacaaacgta ctccagaagg acaggcagcc tttctacgat tcgtagaatt
     9421 tgtaggttta gcaacataaa tgtaagaaag agtgggacgg tgtcctgctc tttttggtat
     9481 aatggaagta ttcacagtgt gagaaggaga tatgatggcg gaaaagagat tggggacact
     9541 gattacagta atagcaggta tagcctgggg cttgtctgga gtgagtggac agtacttgat
     9601 gtctcgtggt gtttcagtgg atatgattac ctccctgcgt ttgttggtgt cgggactctt
     9661 tctcgttggc ctggcttatg ctacagcgaa agaacagcta ttggcagttt tgaaagataa
     9721 aaatgccttg ctaggaattt ttatctttgc catgcttggc ttagttctta atcagacagc
     9781 ctatttacaa gccatctatc ataccaatgc gggaacggct actgttctac aatatctctg
     9841 tcctattttg gttttggcat atacctgttt gaaaaatagg gaaaaaccat cagggattga
     9901 gttgatttca attatcttag ctatagcagg cacttttttg attgcgactc atggcaaatt
     9961 agatgaattg gcagtgactc caatcggttt gttctgggga atcttctcag cctttactta
    10021 tgcgctatat attattttgc caggtaaatt gattcgtcaa tacggcagta taacggtgat
    10081 tggtttaggg atgttaatgg gtggttttgt agtcacgctt ggtttgcaaa cttggcagca
    10141 tcgtcttcct attgatggtg gaagtttcct gggcctgtta ggtattgtcg gagtcgggac
    10201 gatttttgcc tatactgcct ttcttaaagg cgtcagtatg gttggtcctg tcaatggcag
    10261 tcttttggcc tcgattgagc cgattgcatc tgtctttttt gcagtatggt tggtcaatga
    10321 acaattttat gcaattgatt ttgttggaat gttgttgatt ttacttgctg ttttgcttat
    10381 ttctttaaaa gatatattgg ttgcccaaaa gagtattggt taatatactc ttttttgtta
    10441 tactaaagaa aaaacttgaa aggaataaag atgattaaag aattttgttc cgaaaatcat
    10501 gtaggtgtga tgaaggccct atccctagga gctaaacgga ttgagctctg tgataatttg
    10561 gcagtcggag ggacgacgcc gagttatgga gtggtcaaac atgtttgtca actggcccat
    10621 gagaatgaag ccacagtcat gaccatgatt cgccctcgcg gtggagattt ttgctacgat
    10681 aaagcagagg ttgaaatgat ggttgaagat tgtaaagcag cgattgaact gggggcagat
    10741 ggtctggttt atggtttgtt aaccgaggaa aattggttgg acgaaccagc cttggaaaga
    10801 ctgtttgctg tttcgcagga ctgtcagatt gtctttcaca tggcttttga ccaaattcct
    10861 cgcgaacgcc aattcgaggc tcttgattgg ctggtagaac atggagtgac acggattttg
    10921 atgcgtggga gtctgacagg gtctgccttg aacaatgtgg aatggttaca ggaaattgtc
    10981 gcctatgcac aaggtaaaat tgagattttg attggtggag gattgactgt ggacaatgtg
    11041 ccaacgttat tagaagcatt accaatcaat caagtacatg gaacgagatt attttggtaa
    11101 ggtagctttg aaagtgaaat aaattacaga gtaataatcg aagtttattc agaaatgttt
    11161 agaagttaag gtttgtttaa gcattggaag atacaatata tttattcttt ttcatataat
    11221 ctccacggaa gcagtcgaca tgttcggctg ttttcatttt tgtttgttaa agtccggtat
    11281 acagactaga aactgctgcg tctctattga atcccctacg taaagaattg agaactgtgg
    11341 ctgttgaggt gagtgattta gctttggact atgctgttcg tttagcccaa tccttgaata
    11401 gtactttgcg ttatcataat tatgatagct tgattgccat tgctaaaacc aaaggagtag
    11461 aaccgaaagg taaggattgt caatcatttt cagagtacag acagcgttac agtctctatg
    11521 atgctaagaa gttaatttat cgcgctctcg cgtggcgtct attcgatgat agtcatgcag
    11581 attatggaca tgctcttacc attttggggt tggatgagga tgagtcagga gtagagcaaa
    11641 tcggttttgc tttttcaaaa tttactcttg atattgattg attgctaacc catatgattt
    11701 tcattccgaa agattggatt ttggaagaag gtcagattta attcacaact accattacat
    11761 tacctccaga aggcactcgg ttgatccgag tgttttctgc tatcgattcg catttttctt
    11821 agaaaaatgg tataattatc tgataaaaaa ctttggagac gacagtgagt ttagaaaatt
    11881 acatgccgga ttttgccttg gaaaaggctt atgacgtgac cgtcgaaagc ttgaaaaaac
    11941 atggcataaa agtagtgttt gttgacttgg ataatacctt gattgcttgg aataatcccg
    12001 atggtacgcc agagatgcgc cagtggttac atgatttgca ggacgcaggt attcctgttg
    12061 tggtggtgtc taacaataaa tacgaacgtg tcaaacgggc ggttgaaaaa tttgggattg
    12121 aatttgaagc cttcgctctc aagcctttca cctttgggat taaccgtgct ttgaaacgct
    12181 ttgatgtcca gccgtatgag gtaattatga ttggcgatca gctgatgacg gatattcggg
    12241 ctgctaagcg agctggtctc aagtctgtct tggtcaaacc cttgataaag acggactcta
    12301 tcaatacgca gattaaccgt tggcgtgagc gacggactat gaaaaaaatc atcgctaaat
    12361 atggagcgat agactacaag agggagatgt aagtggaaga attattttgt atcggctgtg
    12421 gtgcccagat tcagacgcta gacaaggctg tcgctggttt tacacctcaa tcagccctag
    12481 aaaaaggcct ggaaacaggg caactctact gccaacgttg tttccgtttg cgccattaca
    12541 atgagatttc agatgtcaat atctcagacg atgatttctt gaaactcctc catagcgtag
    12601 gagaaagcga tgccttggtg gttaatgtca ttgatatttt tgatttcaat gggtcagtca
    12661 ttccaggttt acctcgcttt atttctggaa atgacgtgct tttggtcggc aacaagcagg
    12721 acattttacc caagtctgtc aagacaggca aggttactca gtggttgacc gagcgggcac
    12781 atgaaatcgg catgcgaccg gttgatgtgg tcttgacttc agcccaaaat aagcaggcta
    12841 tcaaggattt gattgaaaag attgaacaac accgcaaggg acgggatgtc tatgtggtcg
    12901 gcgtgaccaa tgtcggcaag tcaaccttga ttaacgctat tattcaagaa atcacagggg
    12961 acaaggatgt cattacgact tcacgtttcc ctggaacgac gctggataag attgaaatcc
    13021 ctctggatga tggttcatac atctatgaca cgccaggaat tatccaccgt caccagatgg
    13081 cccattattt gacggctaaa aacctcaagt acatcagccc tcgcaaggaa atcaagccaa
    13141 agacctacca gctcaatcca gaacaaacct tgttcttggc tggtctggga cgatttgact
    13201 ttgtggctgg tgaacgccaa ggctttacgg ccttctttga taatgagctc caactccacc
    13261 gcaccaagtt gcagggagct agcgagtttt atcagaaaca tgcgggctca cttttagtgc
    13321 caccaaccag caaggaattg aaagaatttc ctgaactggt ccgtcatgaa tttaccatca
    13381 acgagaagac ggatgtggtc ttctcaggac ttggttggat tcgtgtcaat gaaaaagcca
    13441 agattgctgc ctgggctcct aagggtgtgg atgtggtcat tcgcaaggcg attatctaat
    13501 actcttcgaa aattaaaagc agacgttgtt gacttgattt gatgaactcc agttctatct
    13561 gcatctgcgt cgcctagtct gattttaatt ttcattgagt ataagaggta tttgatttca
    13621 gtttttacaa ttaaagagaa aggaagttca agtcttctga tttgaacacg ggctaagtat
    13681 atcggcgcaa taaggaaaaa ctttgttttc tttatttccc gattgtaaca gtctcccagt
    13741 ctgttacaac gccctttgtg tataataaat tatgctaact tcaaaacaac gtgccttttt
    13801 gaacagtcag gcacacagtc tcaaacccat cattcagatt gggaaaaatg gtctaaatga
    13861 ccagattaaa accagtgttc gtcaggcact ggatgcgcgt gaattgatca aggtgacctt
    13921 gctacaaaat acggatgaaa acatccacga agtagctgaa atcttggaag aagaaatcgg
    13981 tgtggatacg gtccaaaaaa tcggtcgcat cttgatttta ttcaaacaat ctagcaagaa
    14041 agagaaccgt aaaatttcca aacaggtcaa agaaatctaa gaaggagagc ctatggctat
    14101 tgaactctta acacccttta ccaaggttga attagaggtt gaaaagaaag aaaccaatcg
    14161 caaacaagtg gggattctgg gagggaattt caaccctgtc cacaatgctc acttgattgt
    14221 ggcagaccag gtccgtcaac agttgaagct ggatcaagtc ttgctcatgc cagaattcat
    14281 tccacctcat gtggataaga aagaaaccat tgacgaatac catcgctatt ccatgctcaa
    14341 gatggctatt gcaggtattg agggcttggg gattgaaacc attgaactag aacgccgtgg
    14401 tgtcagctat acctacgaca ccatgaaatt gctgaaggaa aaaaatcctg atacggatta
    14461 ttatttcatc atcggtgcag atatggtaga ctaccttcca aaatggcata ggattgatga
    14521 attggtccag ttggtgcagt ttgttggtgt ccagcgccct cgttacaagg cagggacgtc
    14581 ctatccggtt atctgggtag atgtgccctt gatggacatt tcctccagca tggtgcgtag
    14641 ttttatcaag caaggacggg tgccgaattt tatggtgcct catgaagttc tggactatat
    14701 cgaagaaaaa ggactttacc aatgattgca gcagatttga catttgatcg tcaggctctt
    14761 ttggaaaaaa tccgtgtagc catgaagcca gcgcgcttcc aacatgtttt gggtgtggag
    14821 caggcggcgc ttgtcttggc agaccaatat ggctgtgatc cgaaaaaagc cagtctagca
    14881 gcactcttgc atgactatgc taaggaagtg gaagaccaag tttttttgga cttaattgcc
    14941 aagtatgatt tggacaagga cctgctcaac tgggataata acatctggca cggtgtggtt
    15001 ggcgcctata aaatcgcaga agattttggt ttggaagatg aggagatttt ccaagccatt
    15061 caacgacaca ccgttggggc ggggcagatg accttgctgg acaaggttct ctatgtagcg
    15121 gactacatcg aacccaatcg ggattttcct ggggtggacg aggcgcgtcg tatcgcaaaa
    15181 gagtccttgg acaaggcagt agcctatgaa actgcccaaa ccatttccta cttagccaag
    15241 aaggggattc ccatttatcc acaaattttg gaaacctata atggctatgt tgtttggttg
    15301 aaggagtagg gatgattaca ttatagtcat ttagtttttc ttttattact tcgttaactc
    15361 gctttgccgt actccagtac agcctgcagc tcattgccta gtactaaaag taaactaaaa
    15421 ggctataaaa tatcttgatg aacgttccta tcaagcagtc ttagacttga cagtagccga
    15481 ggaggacaag ggcttcgtgg ctccaaacgt gcgttccttg gcggatgcct ggttatatag
    15541 agagaatggg agtgggaaag aactcgatgg gttctaaaag agttcgtcaa caagtcctta
    15601 tttccagttg ttgagctgaa acagtctatc cccagactgt ttcactccca ccccccgcac
    15661 agctcaaact gtctgggaga cagtttgagg ttggagatga agcgaactct gttcgcatca
    15721 gtcgtagagg ccagatttgg agtgtgtagc acgaacaaag ctgccaatca accactgcgc
    15781 tgagatgttg actagaactt tgagaagtgt acttgcacta gaaccttgcc ccttatgcca
    15841 tctgggcgga tgaacaggtg gttggttttg ccttgattga cattgatgaa gacatccagc
    15901 agtatatgct ctggcgattt atgattggcc aagagtttca aggaaggggc tatggccagg
    15961 cggctttgga agtcgtaata gcaatggctc aatcacatcc tgtctgcgac catttgattg
    16021 cagcctatgt taagggcaat cagaaaatgg ctcatctctt ggagaaaaat aattttgtct
    16081 tggatagtga agaagaaaga gaattggtct tccgtttgga aacgcctggt gttcagctat
    16141 gaaatctgca ttgttagtca ttgacattca gaaccttcta gtggaggaaa aaccttatgc
    16201 cattgaagag cgattagccc tctggtaaga tagccttgca caagcccgtc aagcggggct
    16261 agaagtcatc catgtccgcc atcatgatca ggaattggtc aaggggactg cttgactggg
    16321 agattcactc aattgttgca cccttagcta gtgagaagat tttcgataag tcctttaaca
    16381 gtgccttcaa ggaaacgggg cttcatgctt atttgcagga aaaggaaatt gagcgactca
    16441 ttatcatggg catggcgacc aatttttgca ttgatacgac gattaaagta gcctttgaac
    16501 taggctacaa ggtagctgtg atccagggcg gaacgacgac aggttattca ggtaaattgg
    16561 acgccgaaga cttgattgac cactaccaaa acatctggtc atggaatttt gcccaggtgg
    16621 atagattaga aaatataatt agaggataag atgaaagaac tagatttagt aaaagttgtg
    16681 gttcaggctg ctgatgacaa gcgagctgag gaccttgttg taattgatgt tcaaggcgtg
    16741 accagcctga cagactactt tgtgattgcc agctccatga acagtcgcca gttggaggct
    16801 attgcggaaa acatccgtga aaaggtagcg gatgttggaa tcaagagtag ccgtgtagaa
    16861 ggcgatagta acggtggctg ggtcctattg gatcttggag gcgtagtcgt tcatatcttc
    16921 tcagaagaaa tgcgtgacct ctacaacctt gaaaaattat ggcacgaagg cagcttcttg
    16981 gaagtcgcag actttttaga agaggaatag tgaaacagtt tggggaactg tttcagctgg
    17041 tcaccataaa actcgaaagt gaccaaagag agttcactat tatgtaatta gaagtgatga
    17101 acttcttgaa aaaatatgaa gatagatttt gatttgggtg cactatttga aacttaagtc
    17161 aacatctcag cgcagtggtt gattggcagc tttgttcgtg cttcccactc caaatctgac
    17221 ctaatcaact gtgcgggggc aggaaaacga actctttgga attgaggagt tctttcctgc
    17281 tcccttttta tgaaaggaaa aatgggaaaa tatggcaact tatgaaacat ttgctgcggt
    17341 ctatgatgaa atcatggatg acagcttgta tgataaatgg acagatttta gcttgcggaa
    17401 cttgccacaa gacaccaaga caattttaga attggcctgt gggacaggga ttcaggctgt
    17461 acgttttgct caaaagggct atgaggtgac agggcttgac ctgtcctatg aaatgttgga
    17521 attggcccag aaaaaagcag aagctgctgg tgtcatgatg gaattggccc aagcagatat
    17581 gatggctctg gaaggtgtgg gagatttcga tgcggtgacc tgttattcgg acagtctgtg
    17641 ctatatgtcg gaccgagaag ccgttttgcg ggtctttgaa ggcgttcact cggttctcaa
    17701 tcaaggtggt actttccttt ttgacgttca ctccatctat caaatggagg aagtctttgc
    17761 aggctatagc taccatgaaa actacgagga ttttgccttt gtctgggaca cctatgaggg
    17821 ggagcatgca cattcgattg ttcacgaatt gaccttcttt gtcaaagatg aagccagtca
    17881 agaggagcgg tttatccgtc gggatgaagt gcatgaagag cggacttatc cgattgaaac
    17941 ctatgtggaa ttattgaaag aagctggttt tgcatctgtg gaagtctttg cggactttga
    18001 agatgaagca ccgacagaaa caagccagcg gtggtttttc aagtgtaaaa agtaagattt
    18061 aaaattaaag tgaagttttc gggtcccacc aaattagagt gggattttgt gatataataa
    18121 aaataaatat atctgtaaag gaaaatgaca tggagagttt acatcgtaaa atcagtaact
    18181 ggggtcaaaa aatattcctt cagttcaaaa atagaactcc taatgtggaa gggataagtt
    18241 ttaatagact gacctctaat aaaaatatag atttggaaag ggaaaatcca agctttaaac
    18301 aagcactaga ttttgcaatc caagatgatg agttaaaaaa tgtagcgatc acgggaaatt
    18361 atggctctgg aaaaagtagt ttgcttgatt cttatgaagc gaagtactct aataaaaaat
    18421 tcctccatat ttctctagct gactataaag aaaatgattt atcaggctat aaagaaaatg
    18481 attcatcaga gtcaggaaag aaactaaatg tacgacagat taatgtgatt gaaggcaaga
    18541 tcataaatca attacttcat cagattcatc caaaacatgt aaagaaatcg atttttaaaa
    18601 cattgtctcg aactccaaga agaataccgc ttttattaac tgtatatatt gtactattct
    18661 tcattacact ttcttatttt ttgaaaccca attttttaaa agctttagtc actgctgaca
    18721 aggtatttgg gtgggatgcc aataccgtat ttagctggtt atttttgatt cttcttttta
    18781 ttggctccct tacaacgatt tggtatatag ttgaaaataa gacgataaaa tcattgacaa
    18841 ttggtggcaa aaatgtttca tcagagattg atattttttc tgatcagtcg atgagagttt
    18901 cctattttga caaataccta gatgatgtgt tgtatctttt gaatgaatca agagcagatg
    18961 tcattgtttt tgaggatatc gaccgttttg agaataacac tatttttgcc aagattaagg
    19021 aactaaacgt attagtcaac aataagcgaa aaatagctaa gaaatcatca aagctagtgt
    19081 ttctttacct gatacgagat gatttattca tttcaaaaga aagaactaaa ttttttgatt
    19141 ttatcatccc agtccttcca gttattacga gttcaaactc tagcgataag ttgacaacta
    19201 ctttaaaaga aatgggaata aaatcaggat tagcggatga cttcctcttc agaatctcgc
    19261 tttatataga
//
LOCUS       DBNFCO010000039        19056 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.039, whole genome shotgun sequence.
ACCESSION   DBNFCO010000039 DBNFCO010000000
VERSION     DBNFCO010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 19056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19056
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.039"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(1014..2141)
                     /locus_tag="AC1PIV_001137"
     CDS             complement(1014..2141)
                     /locus_tag="AC1PIV_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HIP6612162.1"
                     /translation="MFHFTTLFIGMDVHKESFSLCYYDMMANQFKHSTKVGPNVSYIV
                     NYVNELRRLYGQDVEVLCGYEAGCLGFTLYHQLQAHGIPCIVMAPTTVMKEGSKRVKT
                     DKKDAAQLTKALAFHSYRPVHISTVEDEQVKEYICMRTDHKVALKKIKQQILAFCLRH
                     DFRYTEGSSNWTQKHVRWLCPLNIDGLYAEILTEYLLTYEKLVDQIERYDARIEQLGQ
                     SDSYQEKVSQLFCFIGIKTLTALSIVTEIGGFNRFATAQHFDFASYLGLTPSENSSGD
                     RERRGAITKTGNSHVRRLLIEAAQSLAKGTIGYKSKELKRRQSGNRVEVIAYADKANE
                     RLRRRYRTLVLGKNKKQNVAKTAIARELSGFIWGMMTGRIA"
     gene            complement(2249..2923)
                     /locus_tag="AC1PIV_001138"
     CDS             complement(2249..2923)
                     /locus_tag="AC1PIV_001138"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamic
                     endopeptidase"
                     /protein_id="HIP6612163.1"
                     /translation="MLKFIKHVALLFLYFVAYQIASGFLMVGPTLQSIPDIPAQLIDS
                     TIWICAIIGLVLSIALIILLWKYIYPRHSVAYRVTASWFHKIQWPILLYIAFFIIQFI
                     VPVPESENQKLVIEFVSAYPLIAFSSVVIFAPILEELIFRGFFATYFFPKMADMKAVG
                     IYLFVTGALFSLVHMPATLPQFLIYFTMGLNLGWLYLIRRDIRYPIALHMLNNGISYL
                     MILFLV"
     gene            complement(2933..3250)
                     /locus_tag="AC1PIV_001139"
     CDS             complement(2933..3250)
                     /locus_tag="AC1PIV_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612164.1"
                     /translation="MKLFLWILVGFLFFNSLSDRKKVKQLQARVKKLQKTTKGENQMS
                     VLLKELIGSKAKIRFDEEFSIAYEYTILAVDEEWVKISRELANGEIETKLVRVDNIID
                     LSF"
     gene            complement(3260..3949)
                     /locus_tag="AC1PIV_001140"
     CDS             complement(3260..3949)
                     /locus_tag="AC1PIV_001140"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamic
                     endopeptidase"
                     /protein_id="HIP6612165.1"
                     /translation="MNRLGNVKDWNVVKNWKFLLVGLAVVALNVLTQLAMFALPNFDG
                     NNLLIAAVLLLLAVVLGLILTGKLGLWKGEQKWGMVANVGFVVLAFIVMFGLKIIGGQ
                     LIMLEEGYGQTTANQEIINNSGLPTLVLFLFAVFFAPVLEELLFRGILMGRVFGKDSI
                     VGLLLSSFLFGLIHNPTNIGSWVVYGGMGLVLGLAYRISGKYTNALILHSLNNLLGFL
                     LMLLMQSLGLI"
     gene            complement(3975..4181)
                     /locus_tag="AC1PIV_001141"
     CDS             complement(3975..4181)
                     /locus_tag="AC1PIV_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009910094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612166.1"
                     /translation="MKENKKFISVLKIVYFVGLIGLGLYAVGYIFGEWLATGQIDLSN
                     LNILLPMVLGLPALLLFKKESDKN"
     gene            complement(4203..4961)
                     /locus_tag="AC1PIV_001142"
     CDS             complement(4203..4961)
                     /locus_tag="AC1PIV_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HIP6612167.1"
                     /translation="MKQGKQISTKQRWMRYSAYMLISAILGGFIGFFGILIFKFSLPS
                     YLNLDNFLICLRIITFLIFAGTVYFGVKANQNYKLYHSISDEDEEHVDELYKKMYRNL
                     EYATISFNVAVSLTLLNLVLGFGVTFFEDGAIMYGSIFDVVFYVILLISQIFIMKLTQ
                     KIRDYKLSAFATVKEMKDFAEAMDEGEKQANYEMSFQIVFTLNQIVLPGLYLFLFVLS
                     MLLQERQITAFLVVAFLHIYINVMQVRMIRRYFK"
     gene            complement(4958..5173)
                     /locus_tag="AC1PIV_001143"
     CDS             complement(4958..5173)
                     /locus_tag="AC1PIV_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HIP6612168.1"
                     /translation="MEYVLKNRLKELRARDGLNQTELAKLAEVSRQTISLIERGEYTP
                     SVVIAMRIAQIFNENVENVFQLVEVEE"
     gene            complement(5186..5752)
                     /locus_tag="AC1PIV_001144"
     CDS             complement(5186..5752)
                     /locus_tag="AC1PIV_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3267 domain-containing protein"
                     /protein_id="HIP6612169.1"
                     /translation="MEAKKKLYEVNIMENKKFVWGLNILAVVLIFPFAFVFGMIVSWL
                     IANGSQYSELSVSEVWLLIPLYILLIVVHEAIHGIFFKVFCPENPVKYGFKWKSGMAY
                     ATSPGSLYNRMQMLVISLAPFVVISLVLTMVAGFGMMNITLYFMLATMHAASCAGDFY
                     YTYLLLVKFAKGNIAVEDTETGLIIYQA"
     gene            complement(5938..6162)
                     /locus_tag="AC1PIV_001145"
     CDS             complement(5938..6162)
                     /locus_tag="AC1PIV_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612170.1"
                     /translation="MKTSSNKKGILITGTSVVRGLEVIIALFLIYAFVQILGFGQPID
                     MVPLLMMVSSLFILKTTLGREKEKKNEQDS"
     gene            complement(6196..6396)
                     /locus_tag="AC1PIV_001146"
     CDS             complement(6196..6396)
                     /locus_tag="AC1PIV_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612171.1"
                     /translation="MKKINNSDMAGFVQLIAIIYLVFVLLADIMKWQQLDQTHVTLAI
                     CAIAVTTGSLKKLGGRKESKVK"
     gene            complement(6605..9223)
                     /gene="alaS"
                     /locus_tag="AC1PIV_001147"
     CDS             complement(6605..9223)
                     /gene="alaS"
                     /locus_tag="AC1PIV_001147"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HIP6612172.1"
                     /translation="MKNLSSAQIRQMWLDFWKSKGHSVEPSANLVPVNDPTLLWINSG
                     VATLKKYFDGSVIPDNPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAIEWGFELLTSPEWFAFPKDKLYMTYYPDDMDSYNRWIALGVEPSHLIPLEDNFWEI
                     GAGPSGPDTEIFFDRGTDFDPENIGIRLLEEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPNKNIDTGAGLERLAAIFQGAKTNFETDLFLPIIREVEKISGKTYDQDGDNMS
                     FKVIADHIRALSFAIGDGALPGNEGRGYVLRRLLRRASMHGQRLGITEPFLYKLVETV
                     GNIMESYYPEVLEKRAFIEKIVKSEEESFARTIHTGSQFAEQLMDKLAAEGKSEIDGR
                     DIFKLYDTYGFQVELTEELAEHRGMTLDIAGFEAAMKEQQDRARASVVKGGSMGMQNE
                     TLAAITEESTFVYGQTALEASLSVIVADNARTEAVSEGQALLVFDQTPFYAEMGGQVA
                     DHGFVKNATGDIVATVIDVQKAPNGQPLHTVELSASISVGQTYTLEIETKRRKGVEKN
                     HTATHLLHAALHNIIGEHATQAGSLNEQDFLRFDFTHFEAVTAEELRRIEEEVNEQIW
                     NAIPVVTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSVELCGGTHVGNTAEIGI
                     FKILKEEGIGSGTRRIIAVTGREAFLAYRDQEDALKEVAATIKSPQIKEVPNKVESLA
                     QQVRDLQKENAALKEKAAAAAAGDVFKNVKDANGIRYIASQVQVSDAGALRTFADNWK
                     QKDYSDVLVLVAAIGDKVNVLVASKSSDVHAGNLIKVLAPIVAGRGGGKPDMAMAGGS
                     DASAIQTLLNSVADNL"
     gene            complement(9503..9988)
                     /locus_tag="AC1PIV_001148"
     CDS             complement(9503..9988)
                     /locus_tag="AC1PIV_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related/scramblase family protein"
                     /protein_id="HIP6612173.1"
                     /translation="MKQFQVKQRFTFGGEKFDIRDSFGNLAYQVEGSFLEIPKRFIVT
                     NSRGGEVCQITKKFLTFLPQFTIDMVEGHSFYLQKEFTFFKDRYTVENLGLILDGNIW
                     DLDFRLKRPDGMLVAEISKELFHLTSHYSVTVLEDSCADLVISLVVAIDYIEMMEDAS
                     T"
     gene            complement(10256..11257)
                     /gene="prsA"
                     /locus_tag="AC1PIV_001149"
     CDS             complement(10256..11257)
                     /gene="prsA"
                     /locus_tag="AC1PIV_001149"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HIP6612174.1"
                     /translation="MKQTKKILAGAVTLFAAVTLAACSNAADKDIITMKGNTITVSEF
                     YEKVKTNSQAQQVLLSMVISNVFENQYGDKVSAEEVNKEYDKKAEQLGASFNAALSSA
                     GLTEESYKEQIRTNKLVEYAVKQAAEKELTDENYKAAYDAYTPEVTARVIKLADEAKA
                     KEVLAAAQAEGADFAQLAKDNSTDTTTKDNGGEVKFDSTSTTVPAEVQKAVFALDAGQ
                     VGASVISSVDMKTYTTSYYVVKLDAKSEKSAKWEDYKDKLKEIILAQKQRDSSFVATV
                     LKEALQKANVKVKDSAFQNLLSQYVTTEESSSSSTKSSSSSTESSSSTTESSSSSGQ"
     gene            complement(11318..12037)
                     /locus_tag="AC1PIV_001150"
     CDS             complement(11318..12037)
                     /locus_tag="AC1PIV_001150"
                     /EC_number="2.1.-.-"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009910106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008171 - O-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HIP6612175.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDFMRTRQAQNTGFLKELEEFA
                     HQENIPVIPHETVAYFRLLMQTLQPKRILEVGTAIGFSALLMADNSPHSKITTIDRNE
                     EMIGFAKENFAKYDYRQQIELLEGEAMDILPTLPDNTYDFIFMDSAKSKYIVFLPEVL
                     KKVKVGGLIILDDIFQGGDVAKDIKDIRRGQRTIYKGLQRLFDATLDNPDVTASLVSM
                     SDGLLMLRKNVENVDLKHIEI"
     gene            complement(12112..12660)
                     /locus_tag="AC1PIV_001151"
     CDS             complement(12112..12660)
                     /locus_tag="AC1PIV_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6630 family protein"
                     /protein_id="HIP6612176.1"
                     /translation="MLTEEQLQDIFELADLMSNGDRELFLQLREVVFASDPHEILNFM
                     ERILDSESFDDFLDRVGESEKENLWLILIKLLEHLNYICVRDYKDNLEDFIYFFDCLQ
                     QVRNAGISLKLDSGGLSPIASISEWARVIDNKYLDENFCLGAVDMDTDSYYLFFSKQA
                     TFIRLQELAGNLGYRIDYAKNM"
     gene            complement(12676..13116)
                     /locus_tag="AC1PIV_001152"
     CDS             complement(12676..13116)
                     /locus_tag="AC1PIV_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612177.1"
                     /translation="MISYKRSIVIPSVISLVLILLGLGGLTKQEPSMGSVVYLIFLQA
                     LLVYLYILRKQKAVFILTKQYLEFQEHFWSERQRHSLEEIAEIRYMVSPVYRGYQSKR
                     LRIVGNKGGLLAVVSLNRLDGADFNDIYHFVEQVAPHIRWDFSN"
     gene            complement(13118..14920)
                     /gene="pepF"
                     /locus_tag="AC1PIV_001153"
     CDS             complement(13118..14920)
                     /gene="pepF"
                     /locus_tag="AC1PIV_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004299006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HIP6612178.1"
                     /translation="MSKQRYEIEEKYQWDLTTIFPTDEAWEAELADLQAETEKTKEFA
                     GHLLDSAKSLLEISETQLSLMRRIEKLYVYASMKNDQDTREGKYQEFQAKAMGLYAVF
                     SQAFAFYEPEFMGITEEKLEAFKVEEPALVQYSHQFEKLLAAKDHVLSQEVEEVLAAT
                     SEIFESPAETFSVLDNASLRFPEITDEDGHLVPLSHGNYIHFMESKNRDVRQEAYEAM
                     YGTYEQFQHTYAKTLQSNVKVNNLKARLRKYDSARHASLAANFIPESVYDTLVAAVNK
                     HLPLLHRYINLRKKLLGIDDLKMYDMYTPLSDFSTKISYEDALKKCQETLEIFGEDYS
                     AIVKEAFENRWIDVHVNEGKRSGAYSGGAYDTNAFMLLNWQDNLDNMYTLIHETGHSL
                     HSMLTRKTQPYVYGHYSLFLAEIASTTNENLLTEKLLAEVEDDKERFAILNHYLDGFR
                     GTVFRQTQFAEFEQAIYKADQEGQVLTADFLNELYGQTNEKYYGLSAEENPEIQFEWA
                     RIPHFYYNFYVYQYATGFAAASALANKIVNGSPEDKENYLNYLKAGSSDYSLNVIAKA
                     GVDMTKEDYLNDAFKVFEARLEELEALVEKGVHL"
     gene            complement(15151..16092)
                     /locus_tag="AC1PIV_001154"
     CDS             complement(15151..16092)
                     /locus_tag="AC1PIV_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HIP6612179.1"
                     /translation="MLVALDEDGQVFNVLENPAPQGSFSCPGCGGLVRYKSGKVLRSH
                     FAHVTLRDCHYFSENESAQHLSLKSCLYRWLVNAEQVELEKCLTSIGQVADLFVNNSL
                     ALEVQCSGLPISRLQLRTQAYSEAGYQVLWLLGKDLWLKERLTNLHKQFLSFSMNMGF
                     HLWELDDEKKELRLRYLIHEDLRGKVHCLTKVFPFGEGNLLDILRLPFAKQALSHLTC
                     PLDRDLPRYIAQQLYYKSPNWLALQAESYSRGENLLTKTAEEWYPHIRLPRSAIGFAQ
                     IQKDLTLVYQDFDQYYGNIEDKQKQVLYPPIIYRKPM"
     gene            complement(16156..18159)
                     /gene="metG"
                     /locus_tag="AC1PIV_001155"
     CDS             complement(16156..18159)
                     /gene="metG"
                     /locus_tag="AC1PIV_001155"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HIP6612180.1"
                     /translation="MTKTPFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGHEV
                     FYLTGLDEHGQKIEEKAKEAGLTPQAYVDGMAVGVKELWNLLDISYDKFIRTTDDYHE
                     EVVAAVFEKLLAQDDIYLGEYSGWYSVSDEEFFTESQLEEVFRDENGKVTGGIAPSGH
                     EVAWVSEESYFLRLSKYQDKLVEFFNAHPDFIQPDGRLNEIMKNFIEPGLEDLAVSRT
                     SFTWGVPVPSNPKHVVYVWIDALLNYATALGYGQEETVNYDKFWNGTVYHMVGKDILR
                     FHSIYWPIMLMMLDMKLPDRLVAHGWFVMKDGKMSKSKGNVVYPEMLVERFGLDPLRY
                     YLMRSLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVAMINKYFGGQVPTFVANVT
                     DFDADLAAVVADNLASYHKYMEAVDYPRALEAVWNIISRTNKYIDETAPWVLAKDEAD
                     RDKLAAVMAHLTAGLRVVAHLIQPFMMTTSNAIMEQLGLGTAFDLENLDFAGLPAGLT
                     VVAKGTPIFPRLDMEEEIAYIQAQMGGSSAISQEEEKEWNPADVELKNEKAAIKFEDF
                     DKVEIRVAEVKEVAKVKGSDKLLKFRLDAGDGQDRQILSGIAKYYPNEQELVGKKVQI
                     VANLKPRKMMGLLSQGMILSAEHGDNLTLLTVDPSVPNGSQIG"
     gene            18315..18908
                     /locus_tag="AC1PIV_001156"
     CDS             18315..18908
                     /locus_tag="AC1PIV_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1361 domain-containing protein"
                     /protein_id="HIP6612181.1"
                     /translation="MFTKKNILTHLFFLIIAVGLKRYGVTAPDLTWNMFLALVALDFA
                     ILTNHTKSHILKVIAGLLWLFFYPNTFYMVTDIVHMHFANTVLWQRESMILFMLYVPS
                     IFFGVMAGVESVRLIFSAFSIKSYWLKLFMISGLSLLSSFAIHIGRYARLNSWDIFTR
                     PTVVIDEMLAVISWDSLPFILGFTFIQIMVLVFSINE"
BASE COUNT         5673 a         4251 c         3461 g         5671 t
ORIGIN      
        1 cggttttgtc aacggttttt atcatttatt ttaaatactt tcaaaacgaa tcttgatata
       61 atcttataaa attcgagtat cttcattccc caagcaataa aatatactta acacaagtat
      121 gattttcttc ttcgatttta tcaatcatta gtaaacattt tacatatcat tattcatata
      181 ttatccaaaa ttggctatac tacattcacg aaagtaaacc atacaaaatg ggagcgggaa
      241 gtgatacgac tgactccctc actaccaatt tcccacctca aacaatctcc agaatattcg
      301 aaaactcaac tactccgccg agatgttaat aggaactcaa acattaacat ttttaccctg
      361 tgtttactac tctaaataaa aaatacccta ttgcaacgtg caacaaggta ccatctatct
      421 caatcatata ttctgtaatt cattttatat agtcatatca gtttatcttt gattacttcg
      481 acgagcgagg aaacgtcgtt tccttatttc caacctagaa cagcttttag gctgttctag
      541 caacctgtag ctattgagga gaacttgctt cgccctatct ccagccttca aaggttcccc
      601 gaacctttga agcgagtact aaaagcaaac taaaagactg atatgtaaag ccctttgtca
      661 agtaaaaaca atcgaactga taaaaaatga aaagtatcta gaaagagcct agtttttagc
      721 ttcgggcatt ggccactcta atattcgtgg attggttacc cacaggtcaa tggttctgcc
      781 gcgagtccta ctctctataa gcgtggatca caattgtgtc acttagttgt ttcgtagatg
      841 actcaaacct tgaagtccta aactccttca agatactctc cattcaaaca ttatttcaat
      901 ccttatttct gtccaaattc acccagtgat ttgggataga aatagggatt cctcatcgct
      961 ctgcgatgat aaaacttaat tgtcaaaagt gtacatgaaa acaagtgcta acttcaagct
     1021 attcttcctg tcatcatccc ccaaataaaa ccagataatt cccgtgcaat agctgtttta
     1081 gcaacatttt gtttcttatt ttttcctaga acaagtgtgc gataacgtct tcttaagcgt
     1141 tcattagcct tatccgcata agcaatcacc tccactcggt ttccactttg tctccttttc
     1201 aattctttgg atttataccc aatcgtcccc ttagccaatg attgtgcagc ttctatcaga
     1261 agtcgtctca catggctatt cccagttttg gtgatagcac ctcttctctc cctgtcgccg
     1321 ctagaatttt cgctaggagt tagcccaaga taagaagcaa aatcaaaatg ttgagctgtc
     1381 gcaaagcggt taaaaccacc gatttccgtc acaatggaaa gagcggttag tgttttaatg
     1441 ccaataaagc aaaaaagctg agagaccttc tcttgataac tgtcgctttg acccagttgc
     1501 tcaattcgcg catcataccg ttctatttga tctactaatt tctcataggt caatagatat
     1561 tctgtcaaaa tctctgcgta aagtccatca atatttaggg gacagagcca gcggacatgt
     1621 ttctgtgtcc aattactgct tccctcggta tagcgaaaat catgtcggag acagaaggca
     1681 agaatttgtt gtttgatttt cttcagagcc actttgtggt ctgttctcat gcagatatat
     1741 tctttgactt gttcatcctc aacagtagaa atatgaacag gccgatagct atgaaaggcc
     1801 agagcttttg tgagctgagc tgcatctttt ttatcagtct taacacgctt agatccttcc
     1861 ttcatcaccg ttgtaggcgc catcacgata cagggaatcc cgtgagcttg tagctggtga
     1921 tatagggtaa atccaagaca tccggcttcg tagccacata acacttctac atcttgacca
     1981 tataaacgac gaagctcatt cacatagttc acaatatagc taacatttgg accaacttta
     2041 gtgctatgtt tgaattgatt cgccatcata tcataatagc agagtgaaaa actttctttg
     2101 tgaacatcca ttccgatgaa aagtgtggta aaatgaaaca tataagacct ccaattgagt
     2161 gtggtaattc ctgttagaag ttgattgttt tttattctag tgtacaggta aatccacgaa
     2221 ttctcaactg ggggtcttta catattgtct ataccaaaaa tagaatcatc aaataggaaa
     2281 ttccattatt taacatatgt agcgcaatcg gataacgaat atctcgtcta attaaataga
     2341 gccaaccaag attgagtccc atcgtgaaat aaatcaaaaa ttggggaaga gttgctggca
     2401 tatggaccag actaaataaa gcccccgtta caaatagata gattccaaca gccttcatat
     2461 ctgccatttt agggaagaaa taggtcgcaa aaaatccacg gaaaatcaat tcttctaaaa
     2521 ttggagcaaa gatcactact gagctaaatg caatcaaggg ataagctgat acgaattcga
     2581 tcacaagctt ttgattttca ctttctggga ctggtactat aaattggatg ataaaaaatg
     2641 caatatagag caatatcggc cattgaatct tatggaacca tgaagctgtc acacgatagg
     2701 caacagaatg acgtggatag atatacttcc ataacagaat aatgagcgca atggagagaa
     2761 caagaccaat tatcgcacaa atccaaattg tactgtcaat caactgggca ggtatgtctg
     2821 gtatgctttg taaagttggt cctaccatca gaaaacctga agcaatttga taggcaacaa
     2881 agtatagaaa tagtaatgcg acgtgtttga taaattttaa cataatccct ccctaaaagc
     2941 tcaagtcaat aatattatcg acccgtacca acttggtttc aatctcccca ttcgctaatt
     3001 cacgagaaat tttaacccat tcctcatcaa ctgccaaaat agtgtattca taagcaatag
     3061 aaaattcctc atcaaagcgg attttggctt tacttccgat caattctttc aataaaacgg
     3121 acatctgatt ttctcctttt gtagttttct gcaacttttt taccctagct tgcaactgct
     3181 tcactttttt cctatctgat agagaattga aaaatagaaa tcctactaga atccataaaa
     3241 atagtttcat cgtatcctcc tatatcaagc ccagactctg catcagtagc atcaacaaaa
     3301 atccaagaag attattcaga ctgtgtagaa taagtgcatt ggtatatttg ccagaaatac
     3361 gataggcgag tcccaggacc aggcccatac ctccgtagac aacccaagat ccgatattgg
     3421 tcggattgtg aataagtcca aacaaaaaac ttgatagcaa taatcccaca atcgaatcct
     3481 taccaaatac tctccccata agaatccctc tgaaaagcag ttcctccaaa actggagcaa
     3541 agaaaactgc aaagagaaac aaaactaagg ttggtaagcc tgaattgttg atgatttcct
     3601 gattggcagt cgtttgacca tatccctctt ccaacataat caattgccca ccaattattt
     3661 tcagaccaaa cataacgata aaagcgagga ctacaaaccc aacattcgca accatccccc
     3721 atttctgctc acctttccat agacctaatt taccagtcaa gataagacca agcaccacgg
     3781 ctaacaataa aagaactgca gcaatcagta gattattacc gtcaaaattt ggtagggcaa
     3841 acatggccaa ctgggtcaat acattcagtg caacgactgc cagtcccact aagagaaact
     3901 tccaattttt aaccacattc caatctttga catttccaag tctattcata gcaatctcct
     3961 tcacatacac taaatcaatt cttatcactt tcttttttga acaatagcag agctggcaag
     4021 cccaaaacca tcggcaagag gatattcaga ttagacaaat caatctgccc agtagccagc
     4081 cattctccga aaatatagcc aactgcgtac agaccgagac cgattaaccc cacgaagtaa
     4141 acaattttta gaaccgatat aaacttttta ttctctttca taatcactac caaaaccttt
     4201 ccttatttaa aataccgacg gatcatgcga acctgcatca cattgatata aatgtgcaaa
     4261 aacgccacaa ctagaaatgc cgtaatttgt cgttcctgca atagcatgct aagtacaaat
     4321 aggaatagat acaaacctgg taacacgatt tgattcaaag tgaagacgat ttggaaactc
     4381 atttcgtagt ttgcttgttt ctcaccttcg tccatcgcct cagcaaaatc cttcatttct
     4441 tttaccgtag caaaagcgga taacttatag tcacgaattt tctgagttaa tttcatgata
     4501 aaaatctgag aaatgagaag aatgacatag aaaactacat caaaaattga cccgtacatg
     4561 atcgccccgt cttcgaagaa ggtaacacca aatcctagaa ccaaatttaa caatgtcaat
     4621 gatacagcaa cattgaatga aatggtcgcg tactctaggt tacgatacat tttcttatat
     4681 agttcatcaa catgttcctc atcctcatct gaaatggaat gataaagttt ataattttga
     4741 ttagctttaa caccaaaata tacggttcca gcgaaaatta aaaatgtaat aatcctcaaa
     4801 caaattagaa aattatctaa attgagataa gaaggtaggc tgaatttaaa gattaatatt
     4861 ccaaagaaac cgataaagcc acccaaaatt gctgaaatca gcatatacgc tgaatatctc
     4921 atccatcttt gtttcgtcga aatttgtttc ccctgtttca ttcttctacc tccactaatt
     4981 gaaagacatt ctccacattt tcattaaaaa tttgtgcaat ccgcatagca atgaccaccg
     5041 agggtgtgta ttctcctcgt tcaatcaagc taatagtctg ccgtgatact tctgccaact
     5101 ttgctagctc tgtctgattg agaccatctc tggctcgcaa ttccttgagc cgatttttta
     5161 agacatattc cataaatttt cctttctagg cttggtagat aatcaagcct gtttctgtgt
     5221 cttcgacagc tatatttccc ttggcaaact tgaccaataa gagataggta tagtagaaat
     5281 cacctgcaca agaggcagcg tgcatggttg ccagcatgaa gtaaagagta atattcatca
     5341 tcccaaaacc tgctaccata gtcaagacca aactaatcac aacaaagggt gctagggaaa
     5401 tcaccagcat ttgcatccga ttgtagaggg aacctggact ggtagcatag gccatgcccg
     5461 atttccattt aaacccgtat ttgacaggat tttcaggaca aaaaaccttg aagaagatgc
     5521 cgtggatagc ctcatgcaca actattaaca gaatatagag tgggataagc aaccatacct
     5581 ccgacacgga tagctccgag tattgcgaac cgttagctat caaccaactg actatcattc
     5641 caaatacgaa ggcaaatgga aagatgagta ccacagcaag aatattcaat ccccacacaa
     5701 atttcttatt ttccatgata ttaacttcat ataatttctt tttagcttcc atttctcttc
     5761 tctttagatt tcattttgta aaatagcaga gctgtcacca atgtcgccag caatggagga
     5821 aatagataac ttctctcagt caaactcatc tcaaaaccta acaaagataa aactttaaac
     5881 accaaaatat ttatcaagaa gagtacgaaa aatagtagga ctactttcac tccgttttta
     5941 actgtcttgt tcattcttct tttccttttc tctgccgaga gtggttttca aaatgaatag
     6001 ggaactcacc atcatcaaga gtggcaccat atctataggc tgaccaaatc caagaatttg
     6061 aacgaaagca tatatcaaaa atagagcaat tataacttcc aaacctcgca caacacttgt
     6121 tcctgtaatc aaaattcctt ttttattgct actggttttc ataattttcc accacctact
     6181 actcgactaa ttttactact ttacctttga ctcttttctg ccacctagtt tcttcaagct
     6241 tccagttgtc actgcgatgg cacaaattgc aagagtcaca tgagtctgat ccaactgctg
     6301 ccacttcata atgtcagcta gtaggacaaa aactagatag atgatcgcga taagttgtac
     6361 aaaacctgcc atgtcactat tgtttatctt tttcatatat agttcctact ttctgtttat
     6421 ttaccagatg gattcgtttt catctttatc tcaatatcat tgtaacactt acttttcttt
     6481 ttgacaacta tcattgtcaa aaaaataata atttttgtca aaaagtttat gaagttcgtc
     6541 aaaatgacta gaataacatg caaaaaactc ttctacccaa tggataaaag agtttattga
     6601 gcgattatag attatcagct acgctgttca agagggtttg gattgcagag gcatcgctac
     6661 cacctgccat ggccatatct ggcttaccac caccacgacc tgctacgatt ggcgcaagga
     6721 ctttgatgag gttacctgca tgaacatcgc ttgacttgct tgccacaagg acattgacct
     6781 tgtcgccgat ggccgcaacc agcaccaaga catctgagta gtctttctgc ttccagttgt
     6841 cagcgaaggt acggagggca cctgcatctg aaacttggac ttggctggca atgtagcgaa
     6901 tgccgttagc atctttgaca tttttgaaga catcaccagc agcggctgcc gctgcttttt
     6961 ctttcagagc tgcattttct ttttgtaggt cacgaacttg ttgtgcaaga ctttcaacct
     7021 tgtttggcac ttccttgatt tgtggtgact tgatggttgc cgctacttct ttgagggcat
     7081 cttcttggtc acgataggca aggaaggctt cacgacctgt taccgcaatg atacggcgag
     7141 tacctgaacc gataccttct tctttcaaaa tcttgaagat accgatttca gcggtgttgc
     7201 caacgtgggt accaccacag agttcgacag aatagtcacc aattgtcacc acacggactt
     7261 ctttaccgta tttttcaccg aagagggcca tagcacccat ttccttagct gtgtcaatat
     7321 cggtttcaac cgttacaact ggaatggcat tccaaatttg ctcattgact tcttcttcaa
     7381 tacgacgaag ttcttccgca gtaactgcct caaagtgcgt aaagtcaaag cggaggaagt
     7441 cttgctcgtt caaggaacca gcctgtgttg catgctcgcc gataatattg tgaagagctg
     7501 catggagcaa gtgagttgct gtgtggttct tctcaacacc cttacggcgt tttgtttcga
     7561 tttcaagtgt gtaggtttga ccaactgaaa tgcttgcgga cagctcaact gtgtgtaatg
     7621 gctgaccatt tggtgctttc tgcacatcga tgacagtcgc aacaatgtct ccagtagcat
     7681 ttttcacaaa accatggtct gcaacctgac cacccatttc tgcatagaat ggtgtttggt
     7741 caaagacaag gagggcttga ccttctgaga ctgcttctgt acgcgcatta tcagccacaa
     7801 tgacagataa gcttgcttca agagctgttt ggccataaac aaaggtcgac tcttctgtga
     7861 tagcagccag ggtttcattt tgcatcccca ttgaaccacc tttgacaact gaagcacggg
     7921 cacggtcttg ttgctctttc atagccgctt caaaaccagc aatgtcaagg gtcataccac
     7981 ggtgctcagc caattcttct gtcaattcta cttggaaacc ataggtatca tagagtttga
     8041 aaatgtcacg accatcaatc tcagacttac cttctgctgc caatttatcc atcaattgct
     8101 cagcaaattg tgaacctgta tggatagtac gagcaaatga ctcttcttca ctcttaacaa
     8161 tcttctcaat gaaggcacgt ttttcaagta cttctggata gtaactttcc atgatattac
     8221 caactgtctc caccaatttg tacaagaatg gctctgtaat gcccaaacgt tgaccatgca
     8281 tagaagcacg acgaaggaga cgacgaagga cataaccacg accttcattt ccaggaaggg
     8341 caccgtcacc aatagcaaaa gaaagggcac ggatgtggtc tgcaataacc ttgaagctca
     8401 tgttgtcgcc atcttggtca taggtcttac cagaaatctt ttctacttca cgaatgattg
     8461 gcaagaagag atccgtttca aagttggtct tagccccttg gaaaatagct gctaaacgct
     8521 ccaaacctgc gcccgtatcg atgtttttgt ttggcaattc cttgtactca gagcgaggaa
     8581 cagctgggtc tgcgttgaac tgggacaata cgatattcca aatctcaatg taacggtcat
     8641 tttcaatatc ttcttccaag agacggatac caatgttttc agggtcaaag tcagtaccac
     8701 ggtcaaagaa aatctccgta tctggaccag aaggacctgc accgatttcc cagaagttat
     8761 cttcaagcgg aatcaagtgg cttggctcaa caccaagggc aatccaacga ttgtatgaat
     8821 ccatatcatc aggatagtaa gtcatgtaga gcttgtcttt tggaaaagca aaccattctg
     8881 ggcttgtcaa gagctcaaag ccccattcaa tcgcttcatc acggaaataa tcaccaatag
     8941 agaagttacc aagcatttca aacatggtgt ggtggcgggc tgtcttacca acgttctcga
     9001 tgtcgttggt acggattgat ttttgggcat ttgtaatccg tgggttatct ggaatgacag
     9061 agccatcaaa gtatttcttg agggttgcca caccagagtt gatccacaaa agagtgggat
     9121 cgtttacagg gacaagattt gctgaaggct caacagagtg accctttgat ttccagaaat
     9181 ccaaccacat ttgacgaatt tgagcagaag ataaattttt cataaactaa gataccaagc
     9241 ccgattagaa ggcgactgaa aaataggaaa ctgacaggaa atcttgattt cctaggcagt
     9301 ttatcttttt tccgagcctt ccgagcgggt tcaatttaac gaaacagtta aattaaacat
     9361 ttcctttcat atagtaataa ttgaggggaa agtccgtagc ccgagttcat ttcagaataa
     9421 actcgatacc ctttcctttc ataagtgata gttaggcggg ttcaatttaa cggaccagtt
     9481 aaactgaatg attatttcac gattaagtcg atgcatcttc catcatttcg atgtagtcaa
     9541 ttgcgaccac taaggaaatg accaaatctg cacaggagtc ctccaataca gtaacggagt
     9601 aatgagaagt taaatgaaag agttctttgg agatttcagc tacgagcata ccatctggcc
     9661 ttttcaagcg aaaatccaaa tcccagatat ttccgtctag gattaaacct agattttcca
     9721 cagtatagcg atccttgaaa aaagtaaatt ccttttgcaa gtagaaagaa tgtccctcta
     9781 ccatatcaat ggtaaactgg ggcaggaagg tcaaaaactt cttagtaatc tgacaaactt
     9841 ccccacctct ggaattggtt acgataaatc gttttggaat ttcgagaaaa gatccctcca
     9901 cttgataagc aagattccca aaactatcac gaatatcaaa tttttcacca ccaaaggtaa
     9961 agcgctgttt cacttgaaat tgcttcatga taacctcccc caaaaaaata acaagaaatc
    10021 aaacgaaggg cgaaaaaccg cggtaccacc ttcattcaat gacttgtcat tctcatttaa
    10081 gaaactgtat ccacaagcaa aaaactttta tatataagcc acaaactgtg aatacaggct
    10141 ctactattca attgtaatat taagtagcaa aatacttggc ttagatggct cgcaacaacc
    10201 gccaattttc tgaactaagg tgtcaagtac caattcttaa taagtaaatc gtcaattact
    10261 gacctgatga actagaagat tctgttgtag aagaagaact ttcagtcgac gaagagctgc
    10321 tcttcgttga ggaagaactg ctttcttctg ttgtcacata ctgtgaaaga agattttgga
    10381 aagcactgtc tttaacctta acgtttgctt tttggagtgc ttctttcagc acagtagcaa
    10441 caaatgatga atctctttgc ttttgtgcca aaataatttc tttcagctta tctttataat
    10501 cttcccattt agcagatttt tctgatttag catccaattt tacaacgtaa taactcgttg
    10561 tatacgtctt catatctacc gaagaaatca ccgacgctcc gacttgacct gcatccaagg
    10621 caaataccgc tttctgtacc tctgctggaa cagttgttga agttgaatcg aatttaactt
    10681 cgcctccatt gtcttttgta gtagtatccg tggaattgtc tttcgccaat tgagcaaaat
    10741 ctgcaccttc agcttgtgca gcagctaaaa cttcttttgc tttagcttcg tctgccaact
    10801 tgatgacacg tgctgttact tcaggtgtat aggcgtcata agctgccttg tagttttcat
    10861 ctgtcaattc tttctcagca gcttgtttta cagcatactc aaccaattta ttggtacgaa
    10921 tttgttcctt ataggattct tctgtcaatc ctgccgaaga aagtgccgcg ttaaaagaag
    10981 caccaagttg ttctgccttc ttatcatatt ccttatttac ttcttctgca gagactttgt
    11041 caccatactg attttcaaat acattactga taaccattga cagcaaaact tgttgagctt
    11101 gtgagtttgt ttttactttc tcataaaact cagacacagt aatcgtgtta cctttcatcg
    11161 taatgatatc tttatcagct gcattggaac aagcagcgag tgttactgca gcaaagagtg
    11221 ttactgcacc tgcgagaatt tttttagttt gtttcattaa agactctctc cttttttcat
    11281 taaccccttt attataacac aaaagcttaa aaacttctta aatttctata tgttttaagt
    11341 caacattctc tacatttttc ctcaacataa ggagaccgtc actcatggaa acaagactag
    11401 cagtcacatc tggattatcc aaagtcgcat cgaataaacg ttgcaatccc ttataaatcg
    11461 ttcgctgccc tcttctgata tccttgatgt ccttggcaac atctcctcct tggaagatgt
    11521 catccaaaat gattaaacca cctactttga cctttttcaa gacttctggt aaaaatacaa
    11581 tatattttga tttagcagaa tccatgaaaa taaaatcata tgtgttatct ggtaaagtag
    11641 gaagaatatc catagcttct ccttccagca attcaatctg ctggcgataa tcatacttgg
    11701 caaagttttc cttagcaaat ccaatcattt cttcatttcg atcaatcgtc gtaatcttcg
    11761 agtgcgggct attgtcagcc atcagtaacg cagagaagcc aatagcagtt ccaacttcta
    11821 aaatacgttt aggttggagt gtctgcatca gcaagcggaa ataagctacc gtttcatgag
    11881 ggataactgg aatgttttct tgatgagcaa actcttccag ttctttcaaa aaccctgtat
    11941 tttgcgcctg acgtgttcgc ataaaatcca caatttcttc cttgacaacc ggacggcgca
    12001 tattgtgatt tgcgttttta ctatatgatt caaccataga atccattata tcataagccg
    12061 acaagatttt cttcctcaat acactaaaag gtaggtttcc ccaccttttc tctacatatt
    12121 tttggcgtaa tcaattcgat accctaaatt tccagctagt tcttgaagtc gaataaaagt
    12181 cgcctgctta ctgaaaaaga gatagtaact atccgtgtcc atatctactg cccctagaca
    12241 aaagttttca tcaagatatt tgttatcaat gactcttgcc cattctgaaa tagatgcaat
    12301 tggacttaat ccacctgaat ccaatttaag agaaattccc gcattgcgga cctgctgaag
    12361 gcaatcaaaa aagtagataa aatcttcaag attgtcctta taatcacgca cacaaatata
    12421 gttcaaatgc tctagtaatt ttatcaagat taaccaaaga ttttcctttt cagactctcc
    12481 aacacgatcc aagaaatcat cgaatgactc tgaatctaaa atacgttcca taaaattgag
    12541 aatctcgtgt ggatcactgg cgaagactac ttctctaagt tggagaaata gttccctatc
    12601 accatttgac attaaatctg ctaattcaaa aatatcttgt agttgttctt ctgttaacat
    12661 agtcccctct ctttattaat ttgaaaaatc ccatcttata tgcggtgcta cttgctctac
    12721 aaaatggtaa atatcattaa aatctgcacc atcaagccta ttcaagctga cgactgcaag
    12781 tagtcccccc ttatttccta caattcgcaa acgtttcgac tgatagccac gatagacagg
    12841 agaaaccatg tatcgaatct ctgcaatctc ttctaacgaa tggcgttgac gttcactcca
    12901 aaagtgttct tgaaattcta ggtactgttt tgtcaatata aaaactgcct tttgctttct
    12961 caatatatat aaataaacta gcaaagcttg taaaaatatc aaatagacaa cacttcccat
    13021 agatggctct tgcttggtca aaccaccaag acccagcaag attaaaacaa ggctaatcac
    13081 actgggaatg acaatcgaac gtttatagga aatcatatta gaggtgcaca cctttctcaa
    13141 cgagagcttc taattcttcc aaacgggctt caaatacctt gaaggcatca ttgaggtaat
    13201 cttccttggt catgtctaca cctgctttgg caatgacatt gagggaataa tctgagctac
    13261 cagccttcaa gtagttgaga tagttttctt tgtcttctgg actaccattg acaatcttgt
    13321 ttgctagagc tgatgctgct gcgaaacctg tcgcatactg atagacatag aaattgtaat
    13381 agaagtgtgg aatacgagcc cactcaaact ggatttctgg attttcttcg gcagaaagtc
    13441 cgtaatattt ctcgtttgtc tgaccgtaca attcattgag gaaatcagcc gtcaagacct
    13501 gaccttcctg gtctgcctta tagatagctt gttcaaactc ggcaaattgg gtctggcgga
    13561 agactgtacc acggaaacca tctaggtaat gatttagaat agcaaagcgt tccttgtcat
    13621 cttctacttc tgccaagagt ttttcagtca gaaggttttc gttggtagtt gaagcaattt
    13681 cagccaagaa aagtgaataa tggccataga catagggttg agtcttacga gtcaacatgg
    13741 aatgaagaga atgtcctgtt tcatggataa gggtgtacat gttatccaag ttatcctgcc
    13801 agttgagaag catgaaggcg ttggtgtcgt aggcacctcc tgagtatgct cctgagcgtt
    13861 ttccttcatt aacatggaca tcaatccagc ggttttcgaa ggcttccttc acaatagccg
    13921 aataatcctc gccgaagatt tccaaggttt cttgacattt tttaagagca tcttcataag
    13981 aaatcttggt gctgaaatct gacaatggtg tgtacatatc gtacatcttc aagtcatcaa
    14041 tccccaggag cttcttacgc aaattgatgt aacgatgcaa gagcggaagg tgcttgttga
    14101 ctgccgccac taatgtatcg taaacagatt ctggaatgaa attagctgca agtgatgcgt
    14161 gacgggctga atcgtacttc cgcaaacgag ctttcaagtt attgaccttg acattagact
    14221 gaagggtctt agcgtatgta tgctggaact gctcataagt accgtacata gcttcatagg
    14281 cttcttggcg gacatcacgg tttttagact ccataaagtg gatgtagttt ccgtgtgaaa
    14341 gtggcaccaa gtgaccgtct tcatctgtga tttctgggaa acgcaggctg gcattgtcca
    14401 agactgagaa ggtttcagct ggtgattcga aaatttcgct ggtcgccgcc aatacttctt
    14461 ccacctcttg tgacaagaca tggtccttag ctgctaaaag tttttcaaat tgatggctgt
    14521 actgaacaag agccggctct tctactttaa aggcttccaa tttctcttca gtaatgccca
    14581 taaattcagg ctcatagaag gcaaaagcct gtgaaaagac agcatacaag cccatggcct
    14641 tagcttgaaa ttcctgatat tttccttcgc gagtatcttg gtcgttcttc atagacgcat
    14701 agacatagag tttttcaatg cgacgcataa gactaagttg cgtttcgcta atttctaaga
    14761 gacttttagc tgagtccagt aaatgacctg caaattcttt tgttttttca gtttcagctt
    14821 gtaaatctgc aagttctgct tcccaggctt catcggttgg gaaaatagtg gttaaatccc
    14881 actggtattt ttcttcaatt tcgtaacgtt gtttagacat aattaatcct ccgtattctt
    14941 tattctaaca taaaaaatcc cctctttcca acggaaagtg agggcttata ggttacttat
    15001 ttcaactgga aaacagtttt tgccattcgc tatcgcaagt cgtcactagg ctaacaaagt
    15061 ctacaacctt caccgacagt agtatgacta acataaaata ttgagcatat tttcaaaagt
    15121 aatatataca cctccatcag ctatctctac ttacattggt tttctataaa ttataggtgg
    15181 atatagaacc tgtttctgct tgtcttcaat attgccgtaa tactggtcaa aatcctgata
    15241 aactagggtt aaatcttttt gtatttgggc aaagccaatg gcagagcggg gcagacggat
    15301 gtgggggtac cattcttctg ccgtctttgt cagcaaattc tcccctcggc tataagactc
    15361 tgcctgcagg gccaaccaat tgggggattt gtaataaagc tgttgagcaa tgtagcgagg
    15421 caaatcccta tctaacgggc aagtaagatg cgataaagct tgcttggcaa atggcagacg
    15481 caagatgtcc aataaatttc cctcgccaaa tggaaaaacc tttgtcagac agtggacctt
    15541 acctcgtaag tcttcgtgaa taaggtaacg aagacgcaat tccttcttct catcatccaa
    15601 ttcccagagg tgaaacccca tattcatact aaaagagaga aattgcttgt gcaaattggt
    15661 cagtcgttcc ttgagccaca aatccttgcc aagcaaccaa agaacctgat aaccagcctc
    15721 actataggct tgcgtcctca gctgcaaacg agaaatgggc agaccggaac attgaacttc
    15781 caaagctaga ctattattga caaataaatc agcgacctgt cctatactag tcaagcattt
    15841 ttcaagttca acttgttcgg cattgactaa ccacctgtac agacaagact tgagggacag
    15901 gtgctgagcg gactcattct cggaaaaata gtggcagtcc cgcagggtta catgggcaaa
    15961 gtgcgaacgc agaacttttc ctgatttgta tcggacaagt cctccacaac ctggacagga
    16021 aaaactgcct tgcggcgcag gattttccaa gacattaaaa acttgcccat cttcatcaag
    16081 tgctactaac atattacctc ctttctatat tagttcgtaa aaaaacaccc agtttaactg
    16141 agtgtttgaa attttttacc caatctgact gccgtttggc acagatggat cgactgttaa
    16201 gagtgttaaa ttgtcaccat gttcggctga taggatcatg ccctgactga gcaagcccat
    16261 catcttacgt ggcttaaggt tggcaacgat ttgaactttc ttgccaacca actcttgctc
    16321 atttggataa tacttggcga taccagacag gatttggcgg tcttgtccat caccagcgtc
    16381 cagacggaac ttgagcaact tgtcagaacc ctttactttg gctacttctt taacttcggc
    16441 cacacggatt tccaccttgt caaagtcctc gaacttgatc gcagcttttt cgtttttgag
    16501 ttccacgtca gctgggttcc actctttttc ttcctcttgg gaaatagcag agctgccacc
    16561 catttgggct tggatatagg cgatttcctc ttccatatcc aaacgtggga agataggcgt
    16621 tccttttgcg accactgtca aacctgctgg aagacctgca aagtcaagat tttcaaggtc
    16681 aaatgctgtt cccaaaccaa gctgttccat aatggcattt gaagtggtca tcatgaatgg
    16741 ctgaatgagg tgagccacca cacgaagacc tgctgttaag tgagccatga ctgctgccaa
    16801 cttgtcacgg tccgcttcgt ccttagccaa gacccaaggt gcagtttcat cgatgtactt
    16861 gttggtacgg gagatgatat tccaaacagc ttccaaggcg cgtgggtagt caacagcttc
    16921 catatacttg tggtagcttg ccaagttgtc agctacaact gccgccaagt ccgcatcgaa
    16981 gtcagtcaca ttggcaacaa aagtaggtac ctgaccaccg aaatacttgt taatcatggc
    17041 aacggtacgg ttgagcaggt ttccaaggtc gttggctagt tcgtagttga tacgaccaac
    17101 ataatcttct ggtgtaaagg tgccatcaga gccgactggc agactacgca tgaggtaata
    17161 acggagtgga tccaagccga aacgctcaac caacatttct ggatagacca cattgccctt
    17221 agacttggac atcttgccat ctttcatgac aaaccagcca tgagcaacca agcggtctgg
    17281 caacttcata tccaacatca tgagcatgat tggccagtaa atggagtgga aacgaagaat
    17341 gtccttgcca accatgtggt aaactgttcc attccagaac ttgtcgtaat taactgtttc
    17401 ttcctgacca taacccaagg cagttgcgta gttgagtagg gcatcaatcc agacatagac
    17461 aacgtgcttt ggattggacg gtacgggcac gccccatgta aatgaagtac gtgacactgc
    17521 caaatcttcc aagcctggct cgatgaagtt tttcataatt tcattgaggc ggccgtctgg
    17581 ctggataaag tctggatgag cattgaaaaa ctcgaccaac ttatcctgat acttgctgag
    17641 gcgaaggaag taggattctt ctgaaaccca ggctacttcg tggccgctcg gagcgatacc
    17701 acctgttact ttgccgtttt catctcggaa gacctcttct aattggctct cggtgaaaaa
    17761 ttcctcgtcc gatacggagt accaaccaga atactctccc aagtaaatgt cgtcctgcgc
    17821 tagcaatttt tcaaaaacag ccgccaccac ttcctcgtgg taatcatcgg tcgtgcggat
    17881 aaatttgtcg taagagatgt ccagcaagtt ccagagctcc ttgacaccaa ccgccatacc
    17941 gtcaacgtag gcttgcggag tcaaaccagc ttcttttgcc ttctcttcaa tcttctggcc
    18001 gtgctcatca agccctgtca gataaaaaac ctcgtggccc atcaggcgtt tgtaacgagc
    18061 caatacatcg caggcaatgg tcgtgtaggc tgaaccgatg tgaagttttc cagacggata
    18121 ataaatcggt gtggtaatgt aaaacggtgt ttttgtcatg tttttttcct ttcaaattca
    18181 gagcaaatga aaccctgtta ttgacaacat cctattttat catattttca gctaaatcac
    18241 aaaatggttc taactacaag tcttcctcta tctatgctat actatgatac aactcaaaca
    18301 gaaagaggtc atctatgttt acaaagaaaa atattcttac tcatctcttt ttcctcatca
    18361 tagcagtcgg actaaaacgg tacggtgtca cagcacctga cttgacatgg aatatgttct
    18421 tggcattggt agcacttgat tttgcaatcc ttaccaatca tacaaagtcc catatcctca
    18481 aagtgatagc aggtctcctc tggctctttt tctaccccaa tactttttac atggtgacag
    18541 acatcgtcca tatgcacttt gccaacacag tactatggca acgagaaagc atgattctat
    18601 ttatgcttta tgttccaagt attttctttg gggtcatggc tggcgttgaa agtgtacgac
    18661 ttattttctc tgctttttct atcaaatcct actggctaaa actgtttatg attagtggtc
    18721 tttccctact atccagcttt gccattcata tcggacgata tgcaagactg aattcatggg
    18781 acatctttac caggccaact gtcgttattg atgaaatgct tgcagttatt tcgtgggatt
    18841 ctctcccctt tatcctcggc ttcaccttta tccaaattat ggttcttgtc ttttcaataa
    18901 atgaataaga tttttatctc atagccatta tcttcaagca tcttcccaca ctcaaggact
    18961 atcgttcctt ttgggaagat ttttcaagga cataaacaaa attttttgat aaatttatat
    19021 cttctccgtt tctctccatt acatttttat ccaaac
//
LOCUS       DBNFCO010000040        19021 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.040, whole genome shotgun sequence.
ACCESSION   DBNFCO010000040 DBNFCO010000000
VERSION     DBNFCO010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 19021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19021
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.040"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            70..1350
                     /gene="aroA"
                     /locus_tag="AC1PIV_001157"
     CDS             70..1350
                     /gene="aroA"
                     /locus_tag="AC1PIV_001157"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HIP6612182.1"
                     /translation="MKLRRSVEKLKGTIRVPGDKSISHRSIIFGSLAKGVTRFHNILR
                     GEDVLSTMQVFRDLGVKIEDNGDIVEVHGVGFDGLQAPKNDLDMGNSGTSIRLISGVL
                     AGQDFEATMFGDDSLSKRPMDRVTIPLSQMGVEISGQTERDLPPLTIKGNKNLKPIRY
                     QLPVASAQVKSALIFAALQAEGESVIVEKELTRNHTEDMIVQFGGQLEVNGKEIRIQG
                     GQEFIAQEITVPGDISSAAFWLVAGLIIPGSKIVLENVGINETRTGILDVIKAMGGKM
                     TLSNIDELAKSATITVETSELKATEIAGELIPRLIDELPIITLLATQAHGTTIIRDAE
                     ELKVKETDRIQVVADALNSMGATIEPTEDGMIIHGPTALHGAEINTFGDHRIGMMTAI
                     AALLAKDGEVVLERAEAINTSYPAFFEHLNSLMD"
     gene            1359..1850
                     /locus_tag="AC1PIV_001158"
     CDS             1359..1850
                     /locus_tag="AC1PIV_001158"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004765 - shikimate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HIP6612183.1"
                     /translation="MPIVLLGFMGVGKTTTAHLLNLPVYDMDHIIEERIGMPIADYFS
                     LEGEASFRQLETEVLKGLLDLPSNCIVSTGGGVIKSEVNRELLLANREDNVLLTASFE
                     VSYQRIRKDRQSQRPLFLQCSKEEFEALYRERMALYQGLADTVIDTDKLIPEQVARKI
                     LCK"
     gene            1841..2668
                     /gene="pheA"
                     /locus_tag="AC1PIV_001159"
     CDS             1841..2668
                     /gene="pheA"
                     /locus_tag="AC1PIV_001159"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002941297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HIP6612184.1"
                     /translation="MQVAYLGPRGSFTHQVAQQVFPTADLQAFETITEVIKAYETGEV
                     TYSVIPVENSIEGSVHETIDYLFHQAEIHAVAEIVQPIAQQLLATSADKAVEVIYSHP
                     QAIAQGKKYIQEHFPQARIEITVSTAYAARFVAEHPEQPFAAIAPQAAAVEYGLEVIA
                     QDIQEISENFTRFWILGDKAPSIALEQVAKKVSLALTLPDNLPGALYKAMSVFSWRGI
                     SLTKIESRPLKTALGEYFFILDLDNQSEELLTYSQKELTSLDITYKVLGNYLVYMTS"
     gene            2680..4005
                     /locus_tag="AC1PIV_001160"
     CDS             2680..4005
                     /locus_tag="AC1PIV_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HIP6612185.1"
                     /translation="MNKNNNILTHHEQLRLDYLQKNIHYLNDKESRELDYLLYKKELR
                     ERHGSPRQSLRSFTPTAYEDDYFEEDYFEEDDEQEELLPRYPERKSRKTRQAKPQRFQ
                     SPRIGPKAKVPKPKKARKKGGFKRFIGFVLLAIALVIVAMGYSFFKGMNSVSEKPVAE
                     VFNGVDTSNGTNILILGTDGRVGESSGETRTDTIMVLNVNNTDNKVKLVSFMRDTLVD
                     IEGYEYKLNTAYTLGEQDNQQGAEEVRKALKNSFDIDIKYYAMVDFATFATTIDTLFP
                     EGVTIDAQFSTINGEVVSSVEVPNDLQLEENAPAYQTIQVGVQQMDGKTLLNYARYRS
                     DDEGDFGRTRRQQEVLSAVMTQAKNPMKLFSGSEAIGKVVAMTPTTVPQSFMWLQGPG
                     LLLDAANGIERVTIPENGDWIDDYDMYGGMALRVDFEKYQQRLAELGLR"
     gene            4071..5432
                     /gene="rlmD"
                     /locus_tag="AC1PIV_001161"
     CDS             4071..5432
                     /gene="rlmD"
                     /locus_tag="AC1PIV_001161"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HIP6612186.1"
                     /translation="MLKKNDIVEVEVVDLTHEGQGVAKIDGFVFFVDNALPGEKISMR
                     ILKLKKNIGFGKVEQWQSFSQDRNQDLDFTYLRTGIADLGHLTYPAQLAFKKKQVENS
                     LRKIAGISEIAVADTLGMDSPLAYRNKAAVPVRRVNGQLETGFFRKNSHDLVPIEDFY
                     IQHKEIDALVLATRDLLRKLDLKPYDEKEQTGLVRNIVVRRGHYSGQLMLVLVTTRPK
                     IFRVETLIERLTSQFPNLVSIVQNINDQNTNAIFGQEFRLLHGSETIADTMLGNEFEI
                     SAPSFYQVNTEMAEKLYQTAIDFAELSADDVVIDAYSGIGTIGLSFAKQVKHVYGVEV
                     VEKAVLDSQKNAARNGIDNVTYVCDSAESAMQKWVADGVKPTVIFVDPPRKGLTESFI
                     KASTSVKPEKIVYISCNVATMARDIKLYEELGYKLTKVQPADLFPNTHHVECVVLLQR
                     SNG"
     gene            5643..5810
                     /locus_tag="AC1PIV_001162"
     CDS             5643..5810
                     /locus_tag="AC1PIV_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612187.1"
                     /translation="MKKKEQSSRQIVMCHLVTILGVDIVKATHLVDELEQLGLIRFDE
                     FGNVGLLVLEG"
     gene            5813..6631
                     /locus_tag="AC1PIV_001163"
     CDS             5813..6631
                     /locus_tag="AC1PIV_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HIP6612188.1"
                     /translation="MKRITANQYQTSERYYKLPKVLFESKRYKDMKLEVKVAYAVLKD
                     RLELSLSKGWIDEDGAIYLIYSNSNLMALLGCSKSKLLSIKKTLRDYGLIDEVQQSSS
                     EKGRMANKIYLGELEHETTPVLHTDGASVKKTLGGSQRKTGPVLNSAPSETEGSETKY
                     SETKGSDFLIEDEEERQLVDEKQEENFTSKVDGVTKYDRDYIWGLVYDQLRQTGLSQS
                     ASDYAMIYFSNRYQYALEHMRFARSAEVIAEYVFNGVLSEWTKQLRRQEVKGGD"
     gene            6780..8135
                     /gene="dcm"
                     /locus_tag="AC1PIV_001164"
     CDS             6780..8135
                     /gene="dcm"
                     /locus_tag="AC1PIV_001164"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000670032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003886 - DNA
                     (cytosine-5-)-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HIP6612189.1"
                     /translation="MKFLDLFAGIGGFRLGMEAQGHECLGFCEIDKFARTSYKAMFNT
                     EGEIEYHDIKEVTDHDFRQFRGQVEVICGGFPCQAFSLAGRRLGFEDTRGTLFFEIAR
                     AAKQIQPRFLFLENVKGLLNHDKGRTFATILSTLDELGYDVEWQVLNSKDFQVPQNRE
                     RVFIIGHSRRYRSRFLFPLKRENSPAHLERLGNINPSKRGLNGEVYLTTGLAPTLTRG
                     KGEGAKIAIPVLTPDSLEKRQHGRRFKENLDPMFTLTSQDRHGVVVAGNLLTSFDQTG
                     RVFDISGLSPTLTTMQGGDKVPKILLREELPFLKIKEATKTGYAKATLGDSVNLAYPD
                     STKRRGRVGKGISNTLTTSDNMGVVVAALEYRQDKWYEVTGIVLEGKLYRLRIRRLTP
                     RECFRLQGFPDWAYERAESVSSKSQLYKQVGNSVTVTVIEAIAREFRRIEEEEKHEPT
                     T"
     gene            8119..8547
                     /locus_tag="AC1PIV_001165"
     CDS             8119..8547
                     /locus_tag="AC1PIV_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612190.1"
                     /translation="MNLLHKKSILECTELEERIHQVETNQLLQKILSLPNFDCDFEVT
                     FEDDYHKEMNDPLFYESNLHRIFDFMETRDIKNGVDTLLTKDNHLAFRAFGENYTARG
                     KDGILTTLVTVKCFGEGRMPIDMSRYFSTPEPTVDNSLTL"
     gene            8558..8941
                     /locus_tag="AC1PIV_001166"
     CDS             8558..8941
                     /locus_tag="AC1PIV_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017770591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612191.1"
                     /translation="MLEVYLGNNADTNQDLLTILTTYGVTYRCTKACDVNREIILSLF
                     AKTTDCFELLSPRFLRFKRQYTISLNELVQLVLQKPDQNLRLPLIVCQNHVYPAIGLD
                     EVRTFLPRQVKEDLFQATLMKQVTG"
     gene            8950..9183
                     /locus_tag="AC1PIV_001167"
     CDS             8950..9183
                     /locus_tag="AC1PIV_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003065178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HIP6612192.1"
                     /translation="MNERFWDNLEIILAEKDLTWAELARKVFKGQYVYPSEFNRLYQK
                     LRHYKSNRLMPQIRWVERIVLVLDIDYEDLFKR"
     gene            9186..9770
                     /locus_tag="AC1PIV_001168"
     CDS             9186..9770
                     /locus_tag="AC1PIV_001168"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamic
                     endopeptidase"
                     /protein_id="HIP6612193.1"
                     /translation="MIRIVLFYLAIQLNGLLVSLYLKEYLTIEGIVLLQLVFLSVTCF
                     EIARHKTVQEKNMTWQNHLRWLLLGFMCMVTFAVFISFLFPVQTRNQELLVEVGKQVP
                     HLIFLLFLVNASVLEEIVYRQLLWEKLTFPFVQIGVTSFLFVLSHGPNQLGSWLIYSC
                     LGLTLAVVRLKTDCMTAIALHLLWNSLVYVLTFL"
     gene            9847..10335
                     /locus_tag="AC1PIV_001169"
     CDS             9847..10335
                     /locus_tag="AC1PIV_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612194.1"
                     /translation="MSSEQQERQAMQYVERSSLLTVRTLLKLLEWSARQALAQDSAYK
                     IGVQKLEELLQSPYAIEAIDVSKDVLDKPIDVEKFKELMESEKLPIAISWQKDYLYFY
                     AKDKTLLDHHLDELLKKLMSNPEKLEGLTFDKTLDQEIELAKEKIRVTEPSAVKTKEV
                     TL"
     gene            10335..12152
                     /locus_tag="AC1PIV_001170"
     CDS             10335..12152
                     /locus_tag="AC1PIV_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000287311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirD4-like conjugal transfer protein, CD1115
                     family"
                     /protein_id="HIP6612195.1"
                     /translation="MYSRQKAFVFGLLGLAFGYFCHRLTLLYDSLTNAPPMDRLAYIL
                     GEGLNQVFNPLWLFTFTQKSLLAFILGILTMMLVYLYVSTGQKVYREGEEYGSARFGT
                     SKEKRYFYSKNPFNDTILARDVRLTLLEKKKPQFDRNKNLIVIGGSGAGKTFRFVKPN
                     LIQLNCSNIVVDPKDHLAEKTGKLFLENSYQVKVLDLVNMTNSDGFNPFRYVETENDL
                     NRMLTVYFNNTKGNGSRSDPFWDEASMTLVRAIASYLVDFYNPPGSSKQEQEARRKRG
                     RYPAFSEIGKLIKLLSKGDNQDKSVLEVLFEDYAKKYGHENFTMRNWADFQNYKDKTL
                     DSVIAVTTAKFALFNIQSVIDLTQRDTMDLKTWGTQKTMVYLVIPDNDTTFRFLSALF
                     FSTVFSTLTRQADVDFKGQLPIHVRSYLDEFANVGEIPDFAEQTSTARSRNMSLVPIL
                     QNIAQLQGLYKEKEAWKTILGNCDSLLYLGGNNEETFKFMSGLLGKQTIDVRSTSRSF
                     GQTGSSSTSHQKIARDLMTADEVGNMKRDECLVRIAGVPVFRTKKYFPLKHKYWKLLA
                     DKETDDRWWNYHINPLAKEEELDLSDYQIRDLSTETSLH"
     gene            12170..12412
                     /locus_tag="AC1PIV_001171"
     CDS             12170..12412
                     /locus_tag="AC1PIV_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612196.1"
                     /translation="MNQKLTGFVYGVDASSMFSQAMSLLQKGLIAVGAFLVVMGIINL
                     STNIKDGGPGVRNAILEIVGGVMVGAAGAFVTQITI"
     gene            12431..13285
                     /locus_tag="AC1PIV_001172"
     CDS             12431..13285
                     /locus_tag="AC1PIV_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003065166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbL"
                     /protein_id="HIP6612197.1"
                     /translation="MIKNVTSPFVFLASEKVSSDSLFEGFQVDLESTANLVKSLADFN
                     PTVWSYMTAITKGIMQPLGVAILAVVLVLEFSKMAKKIANSGGAMTFEAMAPMIVSYI
                     MVAVVITNTTVIVEAIIALASYVIEQVAGLVTNGGANYDTITGIKGSGIVGKMIIGFF
                     AILIWLVRMVSIMVVNILITIRFIQLYLMIPFAPVTIPTFLSDDWRSVGIGYLKNIMV
                     YAVQGILIFLIVSLVPLFESAGKIAVSNGAGVMESLAIMFGGLVQAILLIIALVGSQR
                     TARSILGM"
     gene            13347..13700
                     /locus_tag="AC1PIV_001173"
     CDS             13347..13700
                     /locus_tag="AC1PIV_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HIP6612198.1"
                     /translation="MNTRVFKDISKVQHRAWLGFTTRQVIFVFPAIAITILVLGLNLF
                     YWQFGDWFVYGFVFSFTIPLMLFGVYRPNDLPFEIYLKYCFHYELTVPDRTFTGRKGD
                     QREKIKTLNETKDLF"
     gene            13657..16008
                     /locus_tag="AC1PIV_001174"
     CDS             13657..16008
                     /locus_tag="AC1PIV_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000734154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB4-like conjugal transfer ATPase, CD1110
                     family"
                     /protein_id="HIP6612199.1"
                     /translation="MKKLKHSMKPKTSSNDKKQKTKTQKQEIRPSTVNTLAYQGLFQN
                     GLMQVSPSYFSQTYLLGDVNYQTVGLDDKGAIVEKYSDLINSLDDKTNFQLTIFNQKV
                     NLEKFRKSILYPLQEDGFDAYRDELNRMMDSNLEAGENNFSAVKFLSFGKSDQTPKLA
                     FRSLSQIGEYFKSGFSEIDVSLGLLGGEERVNVLADMLRGENHLPFSYKDLTLSGQST
                     KHFIAPTYLSFKHKNHIELDDRLLQIVYVRDYGMELGDKFIRDLMQSDLEVMISLHAK
                     GSTKSETMIKLRTKKTLMESQKIGEQQKMARTGIYLEKVGHVLENNIDEAEALLQTMT
                     QTGDKLFDTVFLIGVLADTEDQLKQSLDIIKQVAGSNDMIIDNLTYMQEAAFNSLLPF
                     GKNYLEGVSRSLLTSNIAVNAPWTSVDIQDKGGKFYGINQISSNIISIDRGKLNTPSG
                     LILGTSGAGKGMATKHEIITTKLKEADSDTEIIIVDPENEYSIIGQAFGGESIDIAPD
                     STTFLNVLDLSDENMDEDPVKVKSEFLLSWIGKLLDRKMDGREKSLIDRVTRLTYKHF
                     DTPSLVEWVFVLAQQPEQEAKDLALDMELYVEGSLDIFSHRTNIKTDSHFLIYNVKKL
                     GDELKQIALMVIFDQIWNRVVKNQKLGKKTWIYFDEMQLLLLDKYASDFFFKLWSRVR
                     KYGAIPTGITQNVETLLLDANGRRIIANSEFMILLKQAKSDREELVHMLGLSKELEKY
                     LVNPEKGAGLIKAGSTVVPFKNKIPQHTKLFDIMSTDPEKMRT"
     gene            16010..18811
                     /locus_tag="AC1PIV_001175"
     CDS             16010..18811
                     /locus_tag="AC1PIV_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tip lysozyme"
                     /protein_id="HIP6612200.1"
                     /translation="MKEDKKVVKQARKNFRSNLKSARMHYRKEVRTLRQTVPKKGRFR
                     KPAQNSLFQEKKTELKENLLSSQKEAEEKFLKEITYVSPRLLKVKEIKNYRLPHAQER
                     LRTARKHLSEVKLSEKQQAVDSKFTFQKENPSLKSRFQFHQEKSFDRLSAEKEVSSAK
                     REVKQLKKVQKSKKSSTKVRAGLGLAASESLDLIAQEDDLDGLRTLKDTSLKVRRYGR
                     FTYQAGKVAVKSGQTGVRFTKTKFSHGKERFQNFKKGKGFTRQKPLKPRRRYQTFLKL
                     ARKQSVAGFKGIVQAIKGSMTFFSVLAGNPLTWIISGILLILLLMMSFFMSVSGSSVI
                     QQDEIELSKSYTHMTLEDAEHTRTNEKGITFYTKIDEVMVYMNHQYQDYKLDDFMETG
                     GTTYKAFLSQVWTDLNGGDSIKSMSDLYKEPAYKLSDEDQEELKELTEEGNYLALQEL
                     DNPFQGQTDEDSLNMTYRYGYEVIDEKPTLHHHIILEAKEGQVIVAPMDGKVSLDGEN
                     VVLTSGKGVNKTKLTLFGIHSGRVSEHQHVLAGDIIGQTKDGTGLKVTYQKVDDDTDK
                     LVNVNPAFYFPKVIQVQTTILPTIGQFGGDEFERAKAIYDYLKSKGATNQAIAAILGN
                     WSVESSINPKRAEGDYLSPPIGATDSSWDDEGWLSLNGPTIYNGRYPNILKRGLGLGQ
                     WTDTADGSRRHTLLLEYAKGKHQKWYDLGLQLDFMLHGDSPYYTNWLKDFFKNSGSPA
                     SLAQLFLIYWEGNSGDKLLERQTRASEWYYQIEKGFSQPNGGTAQSDPKALEAVRGDL
                     FENSVPGGGDGMGYAYGQCTWGVAARINQLGLKLKGKNGEKIPIISTMGNGQDWVRTA
                     SSLGGETGTSPQAGAILSFAGGGHGTPTEYGHVAFVEKVYPDGSFLISETNYNGNPNY
                     TFRKLSGVDSSLSFAYTTK"
BASE COUNT         5862 a         3476 c         4302 g         5381 t
ORIGIN      
        1 tgtcataaaa atcagaaaat attttataaa tatgataaaa tgaaagtgat actagtttga
       61 ggtaaggata tgaaattaag aagaagcgta gaaaaactaa agggaacgat tcgtgtccca
      121 ggtgataaat caatcagtca tcgttctatt atttttggtt cccttgcaaa aggtgttacc
      181 cgtttccaca atattttacg tggggaagat gtcttgtcaa ccatgcaggt ctttcgtgat
      241 ttgggtgtaa aaattgaaga caatggtgat attgttgaag tacacggtgt tggctttgat
      301 ggtcttcaag cccccaaaaa tgatttggat atgggaaatt ctggaacctc gattcgtttg
      361 atttcaggcg ttttagcagg tcaagacttt gaggcgacta tgtttggtga tgattcctta
      421 tccaaacgtc ctatggaccg agtaactatt ccactcagtc aaatgggagt agagatttct
      481 ggacaaactg aacgtgacct acctccgttg accatcaaag ggaataagaa tttaaaacca
      541 attcgctacc aactccctgt agcctctgct caagtaaaat cagctctgat ttttgctgcc
      601 ttgcaggctg agggagagtc ggtcatcgta gaaaaagagt tgactcgaaa ccatacagaa
      661 gatatgattg tccagtttgg tggacagtta gaagtcaatg gcaaggaaat ccgcatccaa
      721 ggtggtcagg agtttattgc ccaagagatt acagttccag gagatatttc aagtgctgct
      781 ttttggttgg ttgctggctt aatcatacca ggttcaaaaa ttgtccttga aaatgtggga
      841 atcaatgaaa ctcggactgg tattttagat gtcattaaag ctatgggtgg taaaatgact
      901 ctttctaaca tagatgaact tgcaaaatct gctaccatta cagttgaaac gtcggaattg
      961 aaggctacgg agattgcagg cgaattgatt cctcggttga ttgatgagtt gccgattatt
     1021 accttactag cgactcaagc acatggaaca acgattattc gtgatgctga ggagttgaaa
     1081 gttaaagaaa cggatcgtat tcaggttgtt gcagatgctc taaatagtat gggagcaact
     1141 attgaaccaa cagaagatgg tatgattatt cacggaccaa ctgctttaca tggtgctgaa
     1201 atcaatacat ttggtgacca ccgtatcggt atgatgactg ccattgccgc cttgttggcc
     1261 aaagatggag aagttgtatt ggaaagagca gaagctatca atactagcta tcctgccttc
     1321 tttgaacact taaatagttt gatggattag gagaacgtat gccaatcgtt ttacttggat
     1381 ttatgggagt tggaaaaaca acaacagcac atttgttaaa tctccccgtt tacgatatgg
     1441 accatatcat tgaagaacgg attggtatgc ctattgctga ctatttcagt cttgaaggag
     1501 aggcttcgtt tagacaactg gagacagagg tactgaaagg attgctggac ttacctagta
     1561 attgtatcgt atcaactggt ggtggtgtga ttaaatctga agtaaacagg gaattgctgt
     1621 tggcaaatag ggaggacaat gtacttctta ctgcctcctt tgaagtttcc tatcagagaa
     1681 ttcgtaagga tagacagtcg caaagacctc tctttttaca gtgtagtaag gaagagtttg
     1741 aagccctcta tcgtgaacga atggcacttt atcaaggttt agccgatact gtaatcgata
     1801 cagataaact gattccagaa caagtagcaa ggaaaatttt atgcaagtag cctatctagg
     1861 acctcgtggt tcttttacac atcaagtggc ccagcaggtc tttccgactg cggatttgca
     1921 ggcttttgag acgattacag aggttatcaa ggcctacgaa acgggggaag ttacctattc
     1981 cgttattcca gtagaaaact cgattgaagg tagtgttcat gaaacgattg actacctctt
     2041 tcatcaggcg gagattcatg cggttgcaga gattgttcaa ccgattgccc aacaactgtt
     2101 agccacgagt gccgataagg ctgtagaggt tatctattct catccgcagg caattgctca
     2161 ggggaagaaa tatattcagg aacattttcc tcaggctcgt attgaaataa cagttagtac
     2221 agcctatgct gctcgctttg tggcagaaca ccctgaacaa ccatttgcgg caattgctcc
     2281 gcaagcggca gcagttgaat atggactgga agtaattgcg caagacatcc aggaaatcag
     2341 cgagaatttt acacgctttt ggattttggg ggataaggct ccgtctattg ccctggaaca
     2401 agtagctaaa aaagtcagtc ttgcactgac attgccagat aacctgccag gagccttgta
     2461 taaggccatg tctgttttct catggagagg aatcagctta acaaaaatag aaagccgacc
     2521 cctgaaaacg gctttgggtg agtatttttt catactggat cttgacaatc agtctgagga
     2581 attattaacc tattctcaaa aagaattgac tagtttagat ataacctata aagtactagg
     2641 gaattacctg gtctatatga ccagctagga tgaagacaga tgaataaaaa caataatatc
     2701 ctaacccatc atgaacaatt gaggttagat tatttgcaaa aaaatatcca ctacttaaat
     2761 gacaaagaaa gtcgcgagtt ggattatcta ttatataaaa aagagctgag agaacggcat
     2821 ggaagtccaa ggcaatctct acgtagcttc acaccaacgg cttatgaaga tgactacttc
     2881 gaggaagatt attttgaaga ggatgatgag caagaggaac tgttgcctcg ctatcctgaa
     2941 cgtaaatcca gaaaaacaag acaagccaaa cctcaacggt ttcagtctcc tcgtatcggt
     3001 cccaaagcga aagtacctaa acctaaaaaa gctcgtaaaa agggtggttt caagcgcttt
     3061 attggtttcg tattgcttgc tatagcgcta gtgattgtag cgatgggcta tagttttttc
     3121 aaaggtatga atagcgtgag tgagaagcca gtagctgagg tcttcaacgg cgtagataca
     3181 tcgaatggga caaatatttt aattttggga acagacggtc gtgttggcga aagctcaggt
     3241 gaaactcgaa cggataccat catggttcta aatgtgaata acacggataa caaagtcaaa
     3301 cttgttagct ttatgcggga taccttggtg gatattgagg gatatgaata taaactcaat
     3361 actgcctata ctttgggaga acaggataat cagcaagggg ctgaagaagt tcggaaggcg
     3421 ttgaagaata gttttgacat tgatatcaag tactatgcga tggtggattt tgcaaccttt
     3481 gcgacaacga ttgatacact tttccctgag ggcgtaacga ttgatgcaca gttttcaact
     3541 attaatggtg aagtcgttag ctcagtagaa gtgccgaatg atttacagct ggaagaaaat
     3601 gctcctgctt atcaaacgat tcaggtcggt gtacagcaga tggatggtaa gaccttgctt
     3661 aactacgcgc gctatcgttc ggatgatgaa ggtgattttg gtcgtacgag acgtcaacag
     3721 gaagtgctat ctgctgttat gacacaggct aaaaatccaa tgaaactatt ctctggctcc
     3781 gaagctatag gtaaggttgt ggccatgact ccgacaacag taccgcaaag ctttatgtgg
     3841 ctacagggac caggccttct attggatgcg gcaaatggta tcgaacgtgt tacaatccca
     3901 gaaaatggag actggattga cgactatgat atgtatggtg gtatggctct tcgtgttgat
     3961 tttgaaaaat accagcagcg cttggctgag ttaggcctgc gttaagaaat atggtatact
     4021 agaagtgact tcggtcactt tttagtggtc caaaaataga aagtagaatt atgttaaaga
     4081 aaaacgatat tgtcgaagta gaagttgtag atttgacaca tgaggggcag ggtgtggcaa
     4141 aaattgatgg ttttgtcttc tttgtagaca atgctcttcc aggcgagaaa atttccatgc
     4201 gcatcttaaa acttaagaaa aatattggtt ttggtaaggt ggagcaatgg cagagcttct
     4261 cacaagaccg taatcaggac ttggatttta cctatctaag aacaggtatt gctgacttgg
     4321 ggcatctcac ttatccagcc caactagctt ttaagaaaaa acaagttgag aatagtctac
     4381 gtaagattgc aggcatttca gaaatagcag tagcagatac gttgggaatg gacagtcctc
     4441 ttgcttatcg taataaggca gctgttccag ttcgtcgtgt gaatgggcag ttagaaacag
     4501 gattcttccg aaaaaattca catgatttag ttccgattga ggatttttac attcaacaca
     4561 aggaaattga tgccttggtt ctagcgacac gtgacctctt gagaaaatta gacttgaagc
     4621 cttacgatga gaaagaacag acaggacttg tgagaaatat tgttgttcgt cgtggtcatt
     4681 attcaggtca gttgatgcta gttttagtta cgactcgtcc gaagattttc cgtgttgaaa
     4741 cccttattga gcgtttgaca agccaatttc caaatcttgt ttctatcgtt cagaatatta
     4801 atgaccagaa taccaatgct atattcggtc aagaattccg tcttttgcat ggcagtgaaa
     4861 ctattgcaga taccatgttg ggcaatgaat ttgaaatttc tgcaccgtct ttctatcaag
     4921 tcaacacaga aatggctgaa aaactctatc agaccgccat tgattttgca gaattgtcgg
     4981 cagatgatgt cgtgattgat gcctattcag gtattgggac aattggtctc tcctttgcaa
     5041 aacaagttaa gcatgtttac ggtgtagaag tcgttgaaaa ggctgtcctt gatagtcaga
     5101 agaatgctgc tcgaaatggg attgataatg ttacttatgt ctgtgatagc gctgaatccg
     5161 ctatgcaaaa atgggtggca gatggagtca aaccaactgt gatttttgtc gacccaccac
     5221 gaaaaggttt gacagaaagt tttatcaaag caagtacttc tgtaaaacca gagaaaatcg
     5281 tctatatctc ttgtaatgtg gcaaccatgg cgcgtgatat taaactttat gaggaattgg
     5341 ggtacaaatt gacgaaggta cagccggctg atttatttcc aaatacgcat cacgtggagt
     5401 gcgtagtgtt gctacaacga agcaacgggt aaaaatcctt tattttaagc actttttcaa
     5461 gcattttgtc tttattgaaa agagtgattt tgacataaaa aaggttcaaa aaaagtacat
     5521 tgatgtgaat gtctgtttgg atgtcgactg cgtagacaaa aaatagatac gtcataaaat
     5581 ataatagttc agcgagaaca ttttactaat tgttctcgtt tttttatttt caggaggaat
     5641 tcatgaaaaa aaaggaacaa tcatcacgcc aaatcgtgat gtgtcatctc gtgactatct
     5701 taggagttga tattgtgaaa gcaactcatc tggttgatga attggaacaa ctaggtttaa
     5761 tccgatttga tgaattcgga aatgttggac ttttagtctt ggagggataa tcatgaaacg
     5821 tattaccgct aatcaatatc aaacatcaga gcgttattat aaactcccaa aagtcttgtt
     5881 tgagagtaaa cgttataagg atatgaagct ggaggttaag gtagcctacg cggttttaaa
     5941 agataggttg gagctgtctt tgagtaaagg ttggattgat gaagatgggg ctatttattt
     6001 gatttattcc aattcaaatc tgatggcact tttaggctgt tcaaagtcaa aactactctc
     6061 tatcaagaaa accttacgtg actatggctt aattgatgaa gtccaacagt cctcgagtga
     6121 aaaaggtcga atggcaaata aaatttactt gggggaatta gaacatgaaa ctaccccagt
     6181 cttacataca gacggggcta gtgttaaaaa aacactaggg gggtctcaaa gaaagacggg
     6241 gccggtctta aattcagccc ctagtgagac tgaaggaagt gagactaaat atagtgaaac
     6301 taaagggagt gatttcctta ttgaggacga ggaggaaagg cagctggtag atgagaaaca
     6361 agaagaaaac tttacttcaa aagtcgatgg cgtgaccaag tacgatcgag actatatttg
     6421 gggtttggtt tatgaccagt taagacagac aggtctatct cagtcggcta gtgactatgc
     6481 catgatttat tttagtaacc gttatcagta tgctttggaa catatgcgat ttgctcggtc
     6541 agcagaagtg atagctgaat atgtgtttaa tggagtgctg tcagaatgga ccaagcaact
     6601 gagacgacaa gaagtaaagg gaggtgatta agatgatttg gtggatacta ggcggaatct
     6661 atctgatttc tatcatcatt ttgattgttg aaatcatccg tgcacctgaa atggatgaac
     6721 atatataggc aagagtttta caagtgtaag gctctttttt agttggaaag agaggaacaa
     6781 tgaaattttt agatttattt gctgggatag gcggttttag gctaggaatg gaagcacagg
     6841 gccatgagtg tttgggcttt tgtgaaattg ataaattcgc tagaacatcc tataaagcca
     6901 tgtttaacac agaaggagaa atagaatacc atgacattaa ggaggtcaca gaccatgact
     6961 ttagacaatt tagagggcaa gtggaggtta tctgcggggg atttccttgc caagcttttt
     7021 cactcgcagg aagacgactg ggatttgaag atactcgagg gactctcttt tttgagattg
     7081 ctcgagcggc caaacaaatc caaccacgtt ttctattttt ggaaaacgtc aaaggcctac
     7141 tcaatcacga caagggacgg acgttcgcca caatcctctc cacgctggat gaattggggt
     7201 atgatgtcga atggcaggtg cttaacagta aggacttcca agtgccccaa aacagagaac
     7261 gggtctttat tatcggacat tctagaagat accgttccag attcctattt cctctcaaaa
     7321 gagaaaacag cccagctcat cttgaaaggc taggaaatat caatccctct aaacgtggtt
     7381 tgaatggtga agtctatctg acgactggac ttgctcctac actaacgaga ggtaaaggag
     7441 agggggcaaa aatcgccatt ccagtcttaa caccagatag tcttgaaaaa cggcaacatg
     7501 gaagacgctt taaagaaaat ctagacccaa tgtttacatt gaccagtcaa gacagacatg
     7561 gtgttgtcgt cgcaggaaat ctgctgacta gctttgacca gactggaaga gtatttgaca
     7621 tttctggctt gtcaccgacc ttgaccacca tgcagggtgg agataaggtt ccaaagattt
     7681 tgctgagaga ggagctacca tttctgaaaa tcaaggaagc cacaaaaaca gggtacgcaa
     7741 aggcaactct tggagactct gtcaatctag cttatccaga ctcaaccaaa cgtaggggac
     7801 gcgtgggaaa gggaatatcc aataccttga cgacttcaga caatatggga gtggtggtcg
     7861 ctgctctgga atatcgacag gataagtggt atgaagtcac aggcattgtc ttagaaggga
     7921 aactttatcg tctgagaata agacgactga caccaagaga gtgtttcaga cttcaaggtt
     7981 ttcctgattg ggcttatgaa agagcagaga gtgtttccag taagagccaa ctatacaaac
     8041 aggtaggcaa tagtgtgact gtcacagtta ttgaagccat tgcgagagaa tttagaagaa
     8101 ttgaagagga agaaaaacat gaacctacta cataagaaaa gtatcctaga gtgtactgaa
     8161 ttagaagaac gtattcacca agttgaaacc aatcagttac tgcaaaagat attgtcgctc
     8221 cccaattttg attgtgactt tgaggtgact tttgaagatg attaccacaa agagatgaat
     8281 gatcccctat tctacgaatc caatcttcat cggatatttg attttatgga aactagggat
     8341 attaaaaatg gtgtagatac actattgacg aaagacaatc acctggcctt tcgtgccttt
     8401 ggtgaaaatt atactgctag gggaaaggat ggcattttaa cgactctggt gacggtcaag
     8461 tgctttggtg aaggacggat gcccattgat atgagtcgct atttctcaac ccctgaacca
     8521 acagttgaca atagcctaac cctataagga ggagcctatg cttgaggtat atctaggaaa
     8581 taatgccgat acaaatcaag acttactaac cattttgacg acctatggtg tgacttaccg
     8641 ttgtacaaaa gcatgtgatg taaaccgtga aatcatactg tcactctttg ccaaaaccac
     8701 ggattgtttt gagttgctgt cgccacgatt tcttcgcttt aagcgtcaat acaccatcag
     8761 tttaaacgag ctggtccagc tcgttctcca aaagccagac cagaaccttc gtctgcctct
     8821 cattgtctgt cagaatcatg tctatccagc tattgggtta gatgaagtgc gaacctttct
     8881 tcccagacag gtaaaagaag atctatttca ggccaccttg atgaaacaag tgacagggta
     8941 ggtgtgaaga tgaatgaacg attttgggac aatttagaaa tcattctggc agaaaaagac
     9001 ctcacttggg cagaactagc tcgcaaagta ttcaaaggtc aatatgtcta tcccagtgag
     9061 tttaatcgcc tctatcaaaa attgcgacat tacaaatcca atcgtctgat gccacagata
     9121 agatgggttg agcgaattgt tttggtatta gatattgatt atgaagattt atttaagagg
     9181 tgacaatgat aaggatagtg ttgttttatc tagccataca gcttaacggt cttcttgtga
     9241 gtttatacct gaaagagtat ctgacaatag aggggatagt cctgctacaa ttggtctttt
     9301 taagtgtgac ttgctttgag attgcccgtc ataaaacagt tcaagaaaaa aatatgacct
     9361 ggcaaaatca cctaagatgg ttgcttctcg gttttatgtg tatggtgact tttgcagtct
     9421 tcatcagttt tctatttcca gttcagacta ggaatcaaga gttattggta gaagttggaa
     9481 agcaggttcc tcatcttatc tttttattgt ttttggtcaa tgcaagtgtc cttgaagaga
     9541 ttgtttatag gcaattgctg tgggaaaaat tgacattccc ttttgtacaa ataggagtga
     9601 ccagttttct ctttgttcta tcccatggcc ccaatcagtt agggagttgg ctcatctata
     9661 gctgtcttgg gttgaccttg gctgttgttc gattgaaaac agattgtatg acggcaatcg
     9721 ccttacattt actttggaat agtttggttt atgtcttgac cttcttgtga taccaaaatc
     9781 aagagtgctt ccgtattatg gaagcacctt atgtttgata gggaattgaa agaagaggag
     9841 gtcaccatgt catctgaaca acaagaacgt caagcgatgc aatacgtgga aagaagtagt
     9901 ttattaacag tcagaaccct cttaaagctc ttagaatggt cggctaggca agccttagct
     9961 caagattcag cgtataagat tggggttcaa aaattagaag aactccttca aagcccttac
    10021 gccattgaag cgattgatgt tagtaaagac gtcctagata agccaattga tgtggagaaa
    10081 tttaaggagc tgatggagtc agaaaaactg ccaatcgcta ttagttggca aaaggattat
    10141 ctttactttt atgccaagga taagaccttg cttgatcatc acttagatga attgttgaag
    10201 aaactgatgt ctaatccaga gaagctagaa ggtttaacct ttgataaaac cttggaccaa
    10261 gagatagaac tggccaaaga gaaaattaga gtgacagaac cttcggcagt caaaaccaag
    10321 gaggtgacct tgtaatgtat tctaggcaaa aagcatttgt ctttggactc ttgggtcttg
    10381 cttttggcta tttctgtcac cgtctaaccc tactctatga tagtttaacc aatgccccac
    10441 ctatggatcg tttagcctac atcttaggag aagggctaaa tcaagtcttc aatcctttat
    10501 ggctttttac ttttactcaa aaatctcttc ttgcctttat ccttgggatt ctaacgatga
    10561 tgttagtcta tctttatgta tcgacaggac agaaggtcta tcgagaaggg gaagaatacg
    10621 gttctgcccg atttggaacc agtaaggaaa agcgatactt ttacagtaag aatcctttca
    10681 atgacacgat tttagctcgt gatgttcgtc taaccttgtt ggaaaagaag aagccacagt
    10741 ttgaccgaaa taaaaatttg attgtcattg ggggttctgg tgcaggtaaa acctttcgtt
    10801 ttgttaaacc caaccttatc caacttaact gttccaatat tgtcgtagat cctaaagacc
    10861 atttggctga aaagacaggt aaactctttt tagaaaacag ttatcaggtc aaggttttag
    10921 atctagttaa tatgaccaat tcagacggtt ttaatccttt tcgttatgta gaaacagaga
    10981 atgatttgaa ccgcatgtta acggtctatt ttaacaatac caagggaaat ggttctcgca
    11041 gtgatccctt ttgggacgag gcttccatga cattggtgag agctattgcc tcttatttgg
    11101 tggattttta caatcctcca ggaagttcca agcaagagca ggaagcaaga cgtaagcgcg
    11161 gccgttatcc agccttttca gagattggga aactcatcaa actcttatca aagggagaca
    11221 atcaggacaa aagtgttctt gaagtcttgt ttgaagatta tgctaaaaaa tacggtcacg
    11281 aaaactttac tatgcgaaat tgggcggatt tccaaaacta taaagataag accttggatt
    11341 cggtgattgc ggtcacaaca gctaaatttg ccctttttaa tatccaatca gtgattgatt
    11401 tgacgcaaag agacactatg gatttgaaaa cgtggggcac tcaaaagacc atggtctatc
    11461 ttgttattcc agacaatgat acgacctttc gtttcctatc tgctttattt ttctctacgg
    11521 ttttctccac tttgaccaga caggctgatg ttgactttaa agggcaactg ccgattcatg
    11581 ttagaagcta tctggatgag tttgcgaatg tcggagaaat cccagacttt gccgaacaaa
    11641 cctcaacagc tcgctctagg aatatgagtc tagttccaat cttgcaaaat attgcccaac
    11701 tccaaggact ttataaggaa aaagaagctt ggaaaaccat tttggggaac tgtgacagtc
    11761 tcctctattt gggtgggaat aatgaggaaa cctttaagtt catgagtgga cttctaggca
    11821 aacaaactat cgatgtcaga agtaccagtc gttcatttgg tcagactggc tcaagttcta
    11881 cctctcacca gaaaattgcc cgtgacttga tgacagcaga tgaagtagga aatatgaaac
    11941 gagatgaatg tctcgtacgc attgcaggag ttcctgtttt tcggaccaag aaatatttcc
    12001 cactcaaaca caaatattgg aagttgctcg ctgataagga aaccgatgac cgttggtgga
    12061 actatcacat caatcccttg gctaaagagg aagaattgga cttgtcagac tatcaaataa
    12121 gggatttaag cactgaaaca tcactacatt aatagaaatg aggaaaaata tgaatcaaaa
    12181 actaacaggc tttgtatacg gagtggacgc cagctccatg ttctcccaag ccatgtctct
    12241 attacaaaaa ggcttaattg cagtaggagc ctttcttgtt gttatgggca ttatcaacct
    12301 ttcaaccaac attaaagatg gtgggccagg tgtccgaaat gccattctag aaattgttgg
    12361 tggggtcatg gtaggagccg caggtgcttt tgtgacacag attaccattt agaggaggtc
    12421 aggatatgac atgataaaga atgtaacgtc accttttgta tttctagcct ctgaaaaagt
    12481 gtcaagcgat agcctttttg aagggtttca ggtcgattta gaatcaaccg ctaacttggt
    12541 taaatcacta gcggacttta atccgacggt gtggtcttac atgacagcca ttaccaaggg
    12601 gattatgcag cccttgggag tagctattct tgcggttgtt ctcgtactcg aattctcaaa
    12661 aatggccaag aaaatcgcaa actcaggtgg tgcgatgacc tttgaagcca tggcacctat
    12721 gattgttagc tacattatgg tcgcggtcgt gattaccaat acgacggtta ttgtggaagc
    12781 cattatcgct cttgcctctt atgttattga acaagtggca gggcttgtca caaatggtgg
    12841 tgctaattac gataccatca caggcatcaa gggatctgga attgtaggaa aaatgattat
    12901 tggctttttt gcgattctca tttggttggt gagaatggtg agtatcatgg ttgtcaatat
    12961 cttgattacc attcgcttta tccaactcta tctgatgata ccttttgccc ctgttactat
    13021 tccgaccttc cttagtgatg actggagaag tgttgggatt ggctacctta agaacatcat
    13081 ggtctatgcc gttcaaggta ttttgatttt tctaattgta tcgcttgttc ccttgtttga
    13141 gtcggctgga aagattgccg tatcaaatgg agctggagtt atggaatcac tcgccattat
    13201 gtttggtggc ttggtacagg ccatcttgtt aatcattgcc ttagttggca gtcaacgaac
    13261 cgcccgaagt attttgggca tgtaggagga agggaatcat tatctcgcct cctcttttta
    13321 tagcttactt agattggaga acatttatga acactcgtgt ctttaaggac atctcaaagg
    13381 ttcaacacag ggcatggctg ggatttacaa ctagacaggt tatttttgta tttcctgcca
    13441 tcgccataac cattttggta ttaggattga acctatttta ctggcaattt ggggattggt
    13501 ttgtctatgg ttttgttttt agctttacca ttccactcat gttatttggg gtctatcgcc
    13561 ccaacgattt accatttgaa atatacctca agtactgttt tcattatgaa ctaacggtgc
    13621 cagaccgcac atttactgga agaaaaggag accaacgtga aaaaattaaa acactcaatg
    13681 aaaccaaaga cctcttctaa tgacaaaaag caaaagacga aaacacagaa gcaggagatt
    13741 agaccttcta ccgtaaatac gttagcctat caagggcttt ttcagaatgg acttatgcaa
    13801 gtcagtccaa gctatttctc acaaacctat cttttaggtg atgtcaatta tcaaacggta
    13861 ggcttagatg acaaaggagc tattgtggag aaatattctg atttaatcaa ttcgctggat
    13921 gataagacca atttccaact gaccattttc aatcaaaagg tcaatctgga aaaattccgt
    13981 aagagtattc tctatccctt gcaggaagat gggtttgatg cttatcgtga tgaattgaat
    14041 cgcatgatgg attccaactt agaggcgggt gagaacaact tttcggctgt caagtttctt
    14101 tcatttggca agagcgacca aacaccaaaa ctagcttttc gttctctgtc acagattggg
    14161 gaatatttca agagtggctt ttctgagatt gatgtgtctc ttggtctgct tggtggagag
    14221 gagcgagtga atgtccttgc ggatatgtta cgaggtgaaa atcatttacc attctcttac
    14281 aaggatttaa ccctgtcagg tcaatccacc aaacacttta ttgctccaac ctacctttcc
    14341 tttaaacaca agaatcatat tgaattggac gatagattat tacagattgt ctatgttcgt
    14401 gactatggta tggagctagg ggataaattt attcgtgacc tcatgcagtc agatttggaa
    14461 gtgatgatta gcctacatgc taaaggctct accaagtctg aaaccatgat caagctgcga
    14521 accaagaaga ccttgatgga atcacaaaag attggggaac aacaaaagat ggctcggact
    14581 ggaatctatt tggagaaggt cggccatgtt cttgaaaaca acatcgatga agcagaagct
    14641 cttcttcaaa ccatgaccca aacaggagat aagctgtttg acaccgtatt tctaattggt
    14701 gtacttgcag atactgaaga ccaactcaaa caatctcttg atattatcaa gcaagtggcg
    14761 gggtcaaatg atatgattat tgacaacttg acctacatgc aagaagctgc ttttaatagt
    14821 ctcttgccat ttgggaagaa ctatctcgaa ggagtttctc gttctctatt gacttcaaac
    14881 attgccgtga atgccccttg gacttccgtt gatattcagg acaagggtgg gaaattttat
    14941 ggcatcaatc aaatctcaag taatatcatc agtattgacc gtggcaagtt aaatactccg
    15001 tcaggtttga ttttagggac ttctggagcg gggaaaggga tggcgacaaa acatgaaatc
    15061 atcactacta aactcaagga agcagatagt gatactgaaa ttattattgt tgacccagaa
    15121 aatgagtata gtattatcgg tcaagccttt ggcggggaga gtattgatat tgccccagat
    15181 tccactacct tcttaaatgt attagatcta tcagatgaga atatggatga ggatccggtt
    15241 aaggtcaagt ccgaatttct cttgtcttgg attggaaagc tcttggaccg taaaatggat
    15301 ggtcgtgaaa aatccttgat tgaccgtgtg acacgactca cctataagca ttttgacaca
    15361 ccgtccttgg tcgaatgggt ctttgtctta gctcaacaac ctgaacagga agctaaggac
    15421 ttggcactgg atatggaact ctatgtggaa gggtcgctgg acatattttc acatcggacc
    15481 aatattaaaa cagacagtca tttcctgatt tacaatgtca aaaagttagg cgatgaatta
    15541 aaacagattg ccctcatggt tatctttgac cagatttgga atcgtgtggt gaaaaatcaa
    15601 aaactaggga agaagacctg gatttacttt gatgaaatgc agcttctttt attggacaaa
    15661 tatgcctctg atttcttctt taaactctgg agtcgtgtcc gtaagtatgg ggcgatacca
    15721 actggcatta ctcaaaatgt ggagacactt cttttggatg ccaatggcag acgtattatt
    15781 gccaatagcg agtttatgat tctattaaaa caggctaaga gcgatcgcga agaattggtg
    15841 catatgcttg gactttccaa ggaactggag aaatacttgg tcaatcctga aaaaggggca
    15901 ggcttaatta aggccggttc caccgttgtc ccgtttaaga ataagattcc acaacacacc
    15961 aagctctttg acatcatgag tacagaccct gaaaaaatga ggacatgaga tgaaagagga
    16021 taaaaaggta gtcaaacagg ccaggaaaaa ctttcgaagc aacttaaaat cagcccgtat
    16081 gcattatcgg aaagaagtta ggaccttaag acagactgtt cctaaaaaag gacgatttcg
    16141 taaaccagcc caaaattctc tttttcagga aaagaaaaca gagttaaaag aaaatctact
    16201 cagtagccaa aaggaagcag aagagaagtt cctaaaggaa attacctatg tgtctcctag
    16261 attgttgaag gttaaggaaa tcaagaacta tcgacttcca catgcccaag aacgtttgcg
    16321 gacggcaaga aaacatttgt cagaagtgaa actaagtgag aaacaacagg cagttgattc
    16381 caagtttact ttccaaaaag aaaatccttc cctgaagtct cgctttcagt ttcaccaaga
    16441 aaaatcattt gatcgactca gtgcagaaaa agaagtgagt tctgccaaac gtgaagtcaa
    16501 acaactcaag aaagtccaaa agtctaagaa aagttctacc aaagtcagag ctggattagg
    16561 cttagctgca tctgaatccc ttgacctgat agcacaggag gatgatttag atggacttag
    16621 aaccctaaag gatactagcc tgaaagtcag acgctatggc aggtttacct atcaagcagg
    16681 taaggtggca gtaaaaagtg gacagactgg tgtgcggttt accaaaacaa aattttctca
    16741 tggaaaggaa cgattccaga acttcaaaaa gggaaaagga ttcacacgcc agaaacctct
    16801 taaaccaaga agacgctacc aaaccttttt aaagcttgcc agaaaacaaa gtgtcgcagg
    16861 tttcaaagga atcgtccaag ccattaaggg aagtatgact ttcttttctg tccttgcggg
    16921 aaatcctttg acttggatta tctcaggcat tctcttgata ctccttttga tgatgagctt
    16981 tttcatgagt gtttcaggta gtagtgtcat tcaacaagat gaaatagaat tgagtaagag
    17041 ttatacccac atgacgttgg aagatgcgga acatacaaga accaacgaaa agggaattac
    17101 cttttacact aagattgatg aggttatggt ttacatgaat catcaatacc aagactacaa
    17161 gctcgacgat ttcatggaaa cgggtggtac gacctacaaa gcatttctca gtcaagtgtg
    17221 gacggactta aatggtggtg attctattaa atccatgtct gacttgtata aggaacctgc
    17281 ttacaagctg tctgatgagg accaagaaga actaaaggag ttgaccgaag aaggcaacta
    17341 tttagccctt caagaattgg acaatccctt tcagggacag accgatgagg atagcttaaa
    17401 catgacctac cgatatggtt atgaggtcat tgatgagaaa ccaacgcttc atcaccatat
    17461 catcttagaa gcaaaagaag gtcaagtcat tgtagctccg atggatggca aggtatctct
    17521 tgatggagag aacgttgttt tgacatctgg taagggagtg aataagacta aactaacctt
    17581 gtttggcatt cattcaggcc gagtgagtga acatcaacat gtcttggcag gagatattat
    17641 tggtcagacc aaagacggaa cgggtctaaa agtcacctat caaaaggttg atgatgatac
    17701 ggataagttg gtcaatgtca atccagcttt ctactttcca aaagtaatcc aggttcagac
    17761 aaccatcctt ccaactatcg gtcagtttgg cggcgatgag ttcgagagag ccaaggcaat
    17821 ttatgactat cttaaaagca aaggtgcgac caatcaagcc atcgcagcca ttctaggtaa
    17881 ctggtcggta gaatcctcca tcaacccgaa acgtgccgag ggcgactatc tatctccccc
    17941 tattggtgcg acagacagtt cgtgggatga tgagggctgg ctctcactta atggtccaac
    18001 tatatacaat ggacgttacc caaatattct caaacgtggt ttaggcttag gccaatggac
    18061 agataccgcg gatgggtcac gcagacatac cttattgctc gaatatgcca aaggaaaaca
    18121 tcaaaagtgg tatgacttag ggttacaact ggatttcatg ttgcatgggg atagtcctta
    18181 ttacaccaac tggttaaagg acttcttcaa aaattcaggt agtccagcta gtcttgccca
    18241 actctttctc atttactggg aaggaaatag tggtgataag ctacttgaac gtcagacaag
    18301 agcaagtgag tggtattacc aaattgaaaa aggctttagt caacccaacg gtgggacagc
    18361 acaaagtgat ccaaaagcac ttgaagctgt acgaggagac ctttttgaaa actctgttcc
    18421 aggaggtggt gacggtatgg ggtatgccta cggccaatgt acttggggag tcgcagcccg
    18481 tatcaaccaa ctaggtctaa aactcaaagg taaaaatggt gagaagattc ctattatcag
    18541 taccatgggt aatggccaag attgggtacg aacagcctca agtctcggtg gagagacagg
    18601 gacaagtcca caagcaggag ctattctttc ttttgcggga ggaggacatg gcacaccaac
    18661 agaatacggt catgtggctt ttgtggagaa agtctaccca gatggctcat tccttatctc
    18721 cgaaaccaac tataatggca atccaaacta caccttccgt aaattatctg gagtggatag
    18781 tagcttgagt tttgcgtata cgacgaaata aaaagggata tgctaacaat aattggattt
    18841 gttagcatat tgttttgcaa atatttcgta agaaattcta ccttttagtt actttgataa
    18901 gtttagtgat atgatataat actaaggaga ggttactgaa tattttaatg gaaacaatta
    18961 ttgaaaaaat gaaaaaagag tcgaaaactg gtttaacttc tggggatcta gttaaccata
    19021 t
//
LOCUS       DBNFCO010000041        18641 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.041, whole genome shotgun sequence.
ACCESSION   DBNFCO010000041 DBNFCO010000000
VERSION     DBNFCO010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 18641)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18641)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18641
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.041"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            160..1416
                     /gene="pcsB"
                     /locus_tag="AC1PIV_001176"
     CDS             160..1416
                     /gene="pcsB"
                     /locus_tag="AC1PIV_001176"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan hydrolase PcsB"
                     /protein_id="HIP6612201.1"
                     /translation="MKKKILATIMLSTVVLSNANYVAVISANDVDSQIATKNQQISEL
                     TAQQAEAQQQVDAIQGQVDAIVSEQAKLTEENTRLEAESQTLAADIERLSADIVSRDG
                     ALKEQARSAQVDGSASSYINTILDSKSIIDAVSRVNAMREIISANNRMLEQQKADKEA
                     IVEKQKANQEAITTLAANRQKLEDDAQVLQVRQAELEAAKLNLAVQKATAEDEKNSLL
                     VQKAAAEEAARQAAARQAEYQAQQAALAQQQVASVSAPVVSTLVETTVTETVAAPTQT
                     VSQSTPTVSTPTTSTSSGSGSSAAANNARYDASSYPVGECTWGVKSQLSWVGPYWGDA
                     KQWLASARAEGFSTGSTPQVGAIAVWTGGYYGHVAVVTAVQSSTSIQVVESNYMGRRY
                     IGNHRGGYFNPTTTSEGAVYYIYPPY"
     gene            1519..2487
                     /locus_tag="AC1PIV_001177"
     CDS             1519..2487
                     /locus_tag="AC1PIV_001177"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0009156 - ribonucleoside monophosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HIP6612202.1"
                     /translation="MAFTDLKLFALSSNQKLAEQVSKKIGIPLGKSSVRQFSDGEIQV
                     NIEESIRGTHVYILQSTSSPVNDNLMEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLQTAGVNRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGDGYVVVSPDHGGVTRARKLAQFLKTPIAIIDKRRSVDKMNTSEVMNIIGDIKDK
                     TCILIDDMIDTAGTICHAADALADAGATAVYASCTHPVLSGPAMDNISKSAIKKLVVL
                     DTIEIAEDRLIDKIEHISTAELLAEAIIRIHEKRPLSPLFEASRVK"
     gene            2574..3752
                     /locus_tag="AC1PIV_001178"
     CDS             2574..3752
                     /locus_tag="AC1PIV_001178"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HIP6612203.1"
                     /translation="MDLLNRFNKNLNRIEVSMIRQFDQSISDVPGILKLTLGEPDFTT
                     PDHVKEAAKAAIDADQSYYTGMAGLLELRQAAAEFVAEKYNLHYNPENEILSTIGATE
                     ALSASLVAILEAGDTVLLPAPAYPGYEPIVNMVGADIVEIDTTANDFVLTPEMLEEAI
                     IEQGDKLKAVILNYPANPTGVTYSREQIQAFADVLRNYPVFVLSDEVYAELTYTGQPH
                     TSIAEFLPEQTILIQGLSKSHAMTGWRIGLIMSQAPIIAQIIKSHQYLVTAASTAMQY
                     GAVEALKNGKDDALPMRAEYVKRRDYIIEKMTDLGFKIIKPDGAFYIFAKIPAGYNQD
                     SFSFLQDFARKKAVAFIPGAAFGQYGEGYVRISYAASMEKIQTAMARLKEYLEENGTN
                     "
     gene            3739..4521
                     /gene="recO"
                     /locus_tag="AC1PIV_001179"
     CDS             3739..4521
                     /gene="recO"
                     /locus_tag="AC1PIV_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HIP6612204.1"
                     /translation="MERIETRGLVLYNRNFREDDKLVKIFTEKAGKRMFFVKHASKSK
                     LVASIQPLTYADFIVKINDDGLSYIEDFHQVQPFKNINGDIFKLSYATYILALADAAL
                     QDKVYDPALFAFLVKTLDLMESGLDYEVLTNIFEIQLLGRFGISLNFHECAFCHRVGL
                     PFDYSYKYSGVLCPQHYQQDERRAYLDPNVPYLLDQFQAISFDELETISIKPEMKRKL
                     RFFIDQLYEEYVGIHLKSKKFIDDLSSWGQIMKPRTENEETE"
     gene            4518..5525
                     /gene="plsX"
                     /locus_tag="AC1PIV_001180"
     CDS             4518..5525
                     /gene="plsX"
                     /locus_tag="AC1PIV_001180"
                     /EC_number="2.3.1.274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HIP6612205.1"
                     /translation="MKRIAVDAMGGDHAPQAVVEGVNQALAAFPDIEIQLYGDEAKIK
                     QYLTATERVSIVHTTEKINSDDEPVKAIRRKKEASMVLATKAVKDGQADAVLSAGNTG
                     ALLAAGVFVVGRIKNIDRPGLMSTLPTMDGKGFDMMDLGANAENIAHHLYQYGILGSF
                     YAEHVRGVKQPRVGLLNNGTEDTKGTPVHQEAYKLLAEDKSINFIGNVEARELLNSVA
                     DVVVTDGFTGNAVLKTIEGTAKSIVGQLTGSIKNGGLRAKLGGLLVKPTLKKALGAMD
                     YKTAGGAVLLGLKAPVIKAHGSSDAQSIFYTIKQTRSILEAGIVEKSVAKFSVVEESH
                     D"
     gene            5518..5766
                     /locus_tag="AC1PIV_001181"
     CDS             5518..5766
                     /locus_tag="AC1PIV_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantetheine-binding protein"
                     /protein_id="HIP6612206.1"
                     /translation="MTREQVYQRVVELIQDEKGEDFQVQPESTLADNIAADSVEIMEF
                     VLNLEDEFHVDVPDAAIEHFEVLSDIVDFIYKEVKKRS"
     gene            5884..6591
                     /gene="purC"
                     /locus_tag="AC1PIV_001182"
     CDS             5884..6591
                     /gene="purC"
                     /locus_tag="AC1PIV_001182"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HIP6612207.1"
                     /translation="MKTDLLYSGKAKDIYATADSDQIVAVYKDQATAFNGGKKEQIVG
                     KGRLNNLISSLIFEKLNEAGVPTHFIKRLSDSEQLNKKVEIIPLEVVLRNVTAGSFSK
                     RFGVEEGITLSTPIVEFYYKKDELDDPFINDEHIAFLELASQDQIAYIKEETRRINEF
                     LKDLFAQIGLTLVDFKLEFGIDSSGQILLADEFSPDNCRLWDADGNHLDKDVFRRGLG
                     ELTEVYEVVLAKLQEVK"
     gene            6604..10323
                     /locus_tag="AC1PIV_001183"
     CDS             6604..10323
                     /locus_tag="AC1PIV_001183"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HIP6612208.1"
                     /translation="MAKRIFVEKKAAFQIKAEALRKELTHNLQLTSLSSLRLVQVYDV
                     FNLEEDLLEQAIKHIFTEQVTDKVLSDEELGLEGAVYFAIEALPGQFDQRAASSQEAL
                     LLLGSRQEVRVNTGQLYILNGDVQEEELVAIKNYLLNPVDSRFKDMDAPLVAQEFSVS
                     DTVIPSLDFFDSYGVEEFASYKREAGLAMEVEDLLFIQDYFKSIGRVPTETELKVLDT
                     YWSDHCRHTTFETELRSIDFSASKFQKQLQATYDKYLAMRTELGRTDKPQTLMDMATI
                     FGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPFGG
                     AATCIGGAIRDPLSGRSYVYQAMRISGAGDITQPLTATRSGKLPQQIISKTAAHGYSS
                     YGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKENVVREKPVAGDVVILLGGKTG
                     RDGIGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGAVTRLIKKSNDFGA
                     GGVCVAIGELADGLEIDLDKVPLKYAGLNGTEIAISESQERMSVVVRPEDVDAFIAAC
                     RQENIHAVVVAKVTEKPNLVMTWNGQTIVDLERSFLDTNGVRVVVDAKVVDSPVNLPE
                     TRTTSAQTLREDLKDLLSDLNHASQKGLQTIFDSSVGRSTVNHPLGGRHQLTPTESSV
                     QKLPVQQGVTTTASVMAQGYHPYLADWSPYHGAAYAVIEATARLVATGANWSKARFSY
                     QEYFQRMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEDLTVPPTLVAF
                     GVTTADSCKVLSPEFKATGEHIYYLPGQILSEDIDFTLIKSNFKAFEKWQSDYVITAA
                     SAVKYGGVLESLALMSFGNQVGARVELADFETSLTGQLGGFVFTSQEDIPDAVKIGQT
                     TTDFTLVVNGVNLSGQDLQVAFEGKLEEVYPTEFEQATELQDVPAVTSSAVIKAKETV
                     EVPVVYIPVFPGTNSEYDSAKAFEQAGAKVNLVPFVTLDAESIENSVDTMVDNIAKAN
                     ILFFAGGFSAADEPDGSAKFIVTILRNAKVRSAIDQFIEKRGLIIGICNGFQALVKSG
                     LLPYGNFEEAGDTSPTLFYNDANQHIAKMVETRIANVNSPWLAGVQVGDIHAIPVSHG
                     EGKFVVTDEEFATLRDNGQIFSQYVDFTGQPSMDSKYNPNGSSHAIEGITSRNGQIIG
                     KMGHSERYEDGLFQNIPGKKDQGLFVSAVRYFTGK"
     gene            10326..11780
                     /gene="purF"
                     /locus_tag="AC1PIV_001184"
     CDS             10326..11780
                     /gene="purF"
                     /locus_tag="AC1PIV_001184"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009908857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HIP6612209.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPQAAQVTYFGLHSLQHRGQEGAGI
                     LANDGGQLCRHRGTGLIAEVFKNPADLEALTGTAAIGHVRYATSGSASINNIQPFLFD
                     FADMQVGLAHNGNLTNAVSLKAELEKNGSIFSSSSDTEILMHLIRRSHNPDFMGKIKE
                     ALNTVKGGFAYLILLEDKLVAALDPNGFRPLSIGKMKNGAWVVASETCAFEVVGADWV
                     RDVEPGEIVVIDDSGIQYDSYTRDTQLAVCSMEYVYFARPDSVIHGVNVHTARKNMGR
                     RLAQEFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSSVVKGKRVVMIDDSIVRGTTSRRIVQLLRDAGAKEVHVAIGSPELKY
                     PCFYGIDIQTRRELISANHTVEEVCEIIGADSLTYLSLEGMIEAIGIETDAPKGGLCV
                     AYFDGEFPTPLYDYEEEYLRSLEEKTSFYIENVK"
     gene            11836..12858
                     /gene="purM"
                     /locus_tag="AC1PIV_001185"
     CDS             11836..12858
                     /gene="purM"
                     /locus_tag="AC1PIV_001185"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HIP6612210.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERLGVMGALGGFG
                     GMFDLTKLDVKEPVLVSGTDGVGTKLMLAIQYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYIATGKNEPAKLEQVVAGVAEGCVQAGCGLIGGETAEMPGMYGEDDYDLAGFAV
                     GIAEKSQIIDGSKVQEGDILLGLASSGIHSNGYSLVRRVFADVSGDALLPELNGRALK
                     DVLLEPTRIYVQQVLPLVKAGLVNGIAHITGGGFIENVPRMFADNLAAEIEEDKIPVL
                     PIFTALETYGQIKHEEMFEIFNMGIGMVLAVSPGKVEKVRELVGEEVYEIGRIITKED
                     KSVVIK"
     gene            12855..13406
                     /gene="purN"
                     /locus_tag="AC1PIV_001186"
     CDS             12855..13406
                     /gene="purN"
                     /locus_tag="AC1PIV_001186"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HIP6612211.1"
                     /translation="MKRIAVFASGNGSNFQVIAEQFEVAFVFSDRRNAYVLERAEKLG
                     VPTFAFELKEFADKQAYEEAIIQLLDQHQIDLVVLAGYMKIVGPTLLAQYEGRIINIH
                     PAYLPEFPGAHGIEDAWNAGVAESGVTVHWVDSGIDTGQIIKQVRVPRLADDILETFE
                     ARIHEAEYQLYPAVLEELGAVKK"
     gene            13416..14963
                     /gene="purH"
                     /locus_tag="AC1PIV_001187"
     CDS             13416..14963
                     /gene="purH"
                     /locus_tag="AC1PIV_001187"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HIP6612212.1"
                     /translation="MTKRALISVSDKNGIVEFAQELTKLGWEIISTGGTKVALDNAGV
                     ATIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDVDSHLQAAKDHEIGLIDLVVVNL
                     YPFKETILRPDVTYDLAVENIDIGGPSMLRSAAKNHASVTVVVDPADYPTVLGEIAEQ
                     GQTTYPTRQRLAAKVFRHTAAYDALIADYFTKQVGEDKPEKLTITYDLNQPMRYGENP
                     QQNADFYQNALPTDYSIAAAKQLNGKELSFNNIRDADAAIRIIRDFKDRPTVVALKHM
                     NPCGIGQAETIEKAWDYAYEADPVSIFGGIVVLNREVDAATAEKMHPIFLEIIIAPSY
                     SAEALAILTNKKKNLRILELAFDAQDASEVEKEFTGVVGGLLVQDQDVVVESPADWQV
                     VTERQPSEQEWAAMEFAWKSSKYVKSNGIIITNDKMTLGVGPGQTNRVASVRIAIEQA
                     KDRLEGAVLASDAFFPFADNVEEIAAAGIKAIIQPGGSVRDQDSIDMANKYGLTMVFT
                     GVRHFRH"
     gene            15089..16351
                     /gene="purD"
                     /locus_tag="AC1PIV_001188"
     CDS             15089..16351
                     /gene="purD"
                     /locus_tag="AC1PIV_001188"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HIP6612213.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESEQVEQVFVAPGNDGMTLDGIEL
                     VNIGISEHSAIINFAKENDVAWTFVGPDDALAAGIVDDFEQAGLKAFGPSRLAAELEW
                     SKDFAKQIMVKYGIPTAAFGTFSNFEEAKAYIEEQGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAREMLLDNKFGDSGARVVIEEFLAGEEFSLFALVNGDQFYILPTAQDHKRAF
                     DGDQGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPILEGMIADGRSYLGVLYAGLILT
                     DQGPKVIEFNARFGDPETQIILPRLTSDFAQNIDDILHKRPTQLTWLDSGVTLGVVVA
                     SNGYPLDYEKGVELPAKTEGDITTYYAGARFAENSRALLSNGGRVYMLVTTADTVQDA
                     QEKIYSELKNQDTTGLFYRTDIGSKAVK"
     gene            16377..16865
                     /gene="purE"
                     /locus_tag="AC1PIV_001189"
     CDS             16377..16865
                     /gene="purE"
                     /locus_tag="AC1PIV_001189"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HIP6612214.1"
                     /translation="MNIPISIIMGSSSDWKTMKKAADMLDKFGVAYEKKVVSAHRTPD
                     LMFRHAEEARGHGFKVIIAGAGGAAHLPGMVAAKTTLPVIGVPVQSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALTALRILSIEDQTIAAQLADFAKEQEKIAEAMTDD
                     LI"
     gene            16852..17931
                     /gene="purK"
                     /locus_tag="AC1PIV_001190"
     CDS             16852..17931
                     /gene="purK"
                     /locus_tag="AC1PIV_001190"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012774883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HIP6612215.1"
                     /translation="MTSSKTIGIIGGGQLGQMMAISAIYMGHKVITLDPAADCPASKV
                     SEVIVAPYHDVAALKQLAERCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLAKKAGVQVAPYKVVTSSLDLEGLDLSKNYVLKTATGGYDGHGQKVIREEAD
                     LVEASQLANSAECVLEEFVNFDLEISVLVSGNGSDYTVFPVQENIHRNNILYKTIVPA
                     RIFDELAEKAKTMALQIADKLHLVGTLCVEMFVAGQEILVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHIRGILGEPLPPIRLLSPAVMINVLGQDMETVQTFLQENPTAHPHFYGKLE
                     AKHNRKMGHVTVLGEDAESVEEFEN"
     gene            17975..>18641
                     /locus_tag="AC1PIV_001191"
     CDS             17975..>18641
                     /locus_tag="AC1PIV_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612216.1"
                     /translation="MPLPQKIQEEIKRYCNNHLPNNDWYEKEFDFIHDVSLKNRIIRE
                     FKSIRYAYKLYEGITAEEEHLIFEIRSQILAYASIYEAVVEYVLETYYSDTQVYDDLV
                     HQNNVMTKIDIPEEKRKKLERELIHLVDNGTKNIEIHTFFYQRKRKASTSIRFDAKCR
                     AAEELNIISKIYQKGNKVVADLPSDIIEIYEYRNAIHLIAEQRKNIDYELELSQRAYR
                     RMKP"
BASE COUNT         5138 a         3786 c         4714 g         5003 t
ORIGIN      
        1 ctattcaatt tggtcttatt tttcgtgtta caaccattat ttgagcgttt atttggaata
       61 acaaacaaga catagaaatg taataattgc gtaatatact tacgcgattt ttttgataaa
      121 atgagagagt cagaaagtat agaggagtta tgttcggata tgaagaaaaa aatcttggct
      181 acaattatgt taagtacagt cgttctatct aatgctaatt atgtagctgt gattagtgcg
      241 aatgatgtag atagtcagat tgcaacaaaa aatcaacaga ttagtgagtt gacagcacaa
      301 caagcagaag ctcaacaaca agttgatgct attcaaggac aagttgatgc aattgttagt
      361 gaacaggcga aattaacaga agaaaatact cgtttggaag cagaatcgca gacattggcg
      421 gcagatattg agcgtttgtc agctgatatt gtgtcacgtg atggtgcttt aaaggagcag
      481 gcgcgtagtg ctcaagttga tggttctgct tcaagttaca ttaatacaat tttggattca
      541 aaatcaatca ttgatgctgt ttctcgtgtt aatgcaatgc gtgagattat ttcagctaat
      601 aaccgtatgt tagaacaaca aaaggctgat aaggaagcaa ttgttgaaaa acaaaaggca
      661 aatcaagagg caatcactac tttggcagct aatcgccaaa aattggaaga tgacgcccaa
      721 gtattgcaag tgcgtcaggc tgaattggaa gctgctaagt taaatttggc tgtgcagaaa
      781 gctactgctg aagatgagaa aaattcattg ttggtgcaaa aggcagctgc agaagaagca
      841 gctcgtcaag cggcagctcg tcaagcggag tatcaagcac aacaggcagc tctagcacag
      901 caacaagtag cctcagtatc agcaccagtc gtgtcaacgc tagtagaaac tacagtgact
      961 gaaacggttg cagcccctac tcagacagta tcacaatcta caccaacggt aagcacacct
     1021 acaacgtcta catcatcagg ttcaggtagt tcagcggcag caaataatgc gcgttatgac
     1081 gcttcatctt acccagttgg tgagtgtact tggggagtta aatctcaact ttcatgggtt
     1141 ggtccttact ggggagatgc taaacagtgg ttagcatcag cacgtgctga aggttttagt
     1201 acaggttcta ctccacaagt aggtgcgatt gctgtttgga caggtggtta ttatgggcac
     1261 gtagcggttg ttacggctgt tcaatcttca acaagcatcc aagttgttga atcaaactac
     1321 atgggtcgtc gttatattgg taaccatcgt ggtggttatt tcaatccaac aacgacttct
     1381 gagggagcgg tttactacat ttaccctcca tattaagaaa ttttcaaata gagcgtgtgg
     1441 atttgcgctc tatttttgtt tgaaaaatga aggaaaaagg gttaaaatag taaaggtaga
     1501 aatatatagg aggctgtcat ggcgtttact gacttaaaat tgttcgctct ttcgtcaaat
     1561 cagaagttag ctgaacaggt gtcgaaaaaa ataggaattc ctctgggaaa atcaagtgtt
     1621 cgtcaatttt cagatggtga gattcaggta aatattgagg aatccattcg tggaactcat
     1681 gtgtatattc ttcaatccac tagctcacca gttaatgata atttaatgga aattttgatt
     1741 atggtcgatg ctcttaaacg tgcatctgct gaatcagtaa acgtagtaat gccttattat
     1801 ggttatgcac gccaagaccg gaaggctcgt gcacgggaac caattacatc aaaattggtg
     1861 gctaatatgt tgcagacagc gggggtcaat cgtttgttga caattgattt gcatgctgcg
     1921 cagattcagg gattcttcga tattcctgtt gatcatttga tgggtgctcc attgattgcg
     1981 gattattttg agcgtcgtgg tatggtaggt gatggctatg ttgttgtatc ccctgaccat
     2041 ggtggtgtga cacgtgcccg taagttagca cagttcttga agacaccgat tgctattatt
     2101 gataaacgcc gtagtgttga taagatgaat acatcagaag tgatgaacat tattggcgat
     2161 attaaggata aaacttgtat cttgattgat gatatgattg atactgcggg taccatctgt
     2221 catgcagcgg atgctttggc agatgcaggg gcaacagctg tttatgcttc atgtacgcac
     2281 ccagtattgt cagggcctgc tatggataac attagtaagt cagcaattaa gaaattggtt
     2341 gttcttgata caattgaaat tgcagaagat cgcttaatcg ataaaatcga acatatttca
     2401 acggcagaat tattagcgga agcgattatt cgtattcatg aaaaacgtcc tttgtcacct
     2461 ttgtttgagg caagtcgtgt taaataggta tgagaagagt caaatgactc ttctttttta
     2521 catttatttt caaaatgtat tataatagtt ttatatgttt ttgaggtggc agaatggatt
     2581 tattgaatcg ttttaataag aatttgaatc ggattgaggt ttcgatgatt cgtcagtttg
     2641 atcagtctat ttcggatgtt cccgggattt tgaaactgac cttgggagag cctgatttta
     2701 caacgcctga tcatgtaaaa gaagcagcta aggctgctat tgatgctgat cagagttatt
     2761 atactggaat ggctggtctt ttggagttgc gtcaggctgc agctgagttt gtggctgaaa
     2821 aatataattt acactacaat ccagaaaatg aaatcctctc tacaatcggt gcgacagaag
     2881 ctctgtcagc gagtttagtt gctattttgg aggctgggga tacagttctt ctgcctgccc
     2941 ctgcctatcc tggttatgag ccgattgtca atatggtggg agcagacatc gttgaaatcg
     3001 atacgacggc aaatgatttt gtattgacac ctgagatgtt ggaagaggcg attattgagc
     3061 agggtgataa gctaaaagct gtcattctca actatcctgc caatccaaca ggtgtgacct
     3121 actcacgtga gcagattcag gcttttgcgg atgtcttgcg taactatcct gtctttgtcc
     3181 tatcagatga ggtctatgcg gagttgactt acactggtca gcctcatact tcgattgcgg
     3241 agtttttgcc agaacagacc attttgattc agggattgtc caagtcccat gctatgacag
     3301 gttggcggat tggcttgatt atgagtcagg ctcccatcat cgctcaaatt atcaagagcc
     3361 atcagtatct tgtgactgca gcgtcaactg ctatgcagta tggtgcggtt gaggccttga
     3421 aaaatggtaa ggatgacgct cttccgatgc gggcggagta cgtcaagcgt agggattaca
     3481 tcatcgagaa gatgacggac ttgggcttta aaattatcaa gcctgatgga gcattttaca
     3541 tctttgcaaa aattcctgcg ggttacaatc aagattcctt tagcttcttg caagactttg
     3601 cgagaaagaa agcggtggcc tttattccag gcgcagcctt cggtcagtat ggagaaggct
     3661 atgtgcgaat ttcctacgca gcaagtatgg agaagattca aacagccatg gctcgtttga
     3721 aggaatatct agaagaaaat ggaacgaatt gaaaccaggg gattagtcct atataatcgg
     3781 aattttcgag aagatgacaa gctggtcaag atttttacag agaaggctgg taagcgaatg
     3841 tttttcgtga aacatgcctc taaatccaag ctggtagctt ctatccagcc tttgacctat
     3901 gcggatttta tcgttaaaat caatgatgat gggctgtctt atatcgaaga ttttcatcag
     3961 gtacagccct ttaagaatat taacggtgat attttcaagc ttagctatgc tacctatatc
     4021 ttggccttgg ccgatgcggc cttgcaggac aaggtctatg acccagctct ctttgctttt
     4081 ttggtcaaga ccttggactt gatggagtca ggtttggact acgaagttct gaccaatatc
     4141 tttgaaattc agctcttggg tcgatttggg atcagtctga attttcacga gtgtgctttt
     4201 tgtcatcggg ttggcttgcc ttttgactat tcctacaagt acagcggtgt cttgtgtccg
     4261 caacactatc aacaagatga gcgacgggct tatctggatc caaatgttcc ctatctactt
     4321 gatcaatttc aggctatttc ctttgatgag ctggaaacca tttccatcaa gcctgagatg
     4381 aagcgaaaat tacggttttt tattgaccag ctgtacgagg aatatgtggg gattcacttg
     4441 aaatccaaga aatttataga tgatttgtct tcttgggggc agattatgaa accaagaaca
     4501 gaaaatgagg aaacagaatg aaacgtattg cagtagatgc tatgggtggg gaccacgccc
     4561 ctcaggcagt ggtagaaggt gtcaatcaag ccttggctgc ctttccagac attgaaattc
     4621 aactttatgg tgatgaggct aaaatcaagc agtatttgac agcgacagag cgtgtcagta
     4681 tcgtccatac gacggagaaa atcaattcag atgatgagcc tgtcaaggct attcgtcgga
     4741 agaaagaggc ttctatggtc ctagcgacca aggctgtcaa ggatggtcag gcagatgcgg
     4801 tcttgtcagc tggaaataca ggtgctcttt tggcggcagg cgtctttgtc gtcggtcgca
     4861 tcaagaacat cgaccgtcct ggtcttatgt ccactcttcc tactatggac ggtaagggat
     4921 ttgatatgat ggatttgggg gcaaatgctg aaaatatagc tcatcatctc tatcagtatg
     4981 gtattcttgg ctcattttac gcggagcacg tgcgtggtgt caaacaacct cgtgtgggac
     5041 ttttgaacaa cggtacggaa gataccaagg gcacgccagt tcaccaagaa gcctataaac
     5101 tcttggcgga agacaagtcg attaacttta ttggaaatgt ggaggcacgt gagttgctca
     5161 acagcgtggc ggatgtggtc gtgacggatg gtttcacggg aaacgctgtg ctaaaaacca
     5221 ttgagggaac tgcaaaatcc atcgttggtc agttgactgg ctcaatcaag aatggcggtc
     5281 tgcgtgctaa attgggaggc ttgctggtca aaccaacctt gaaaaaggcc ttgggggcta
     5341 tggactataa aactgcaggt ggtgctgtct tgcttggtct gaaagcacct gtcatcaagg
     5401 cgcacggctc tagcgatgcc cagtcgattt tctatacgat taagcagacg cgttcgattt
     5461 tggaggctgg cattgttgaa aaatcagtgg ccaaattttc agtagtggag gagagtcatg
     5521 actagagagc aggtctatca gcgggttgtt gaattaattc aggatgaaaa gggagaagat
     5581 tttcaagttc aacctgaatc tactttggca gataatattg cagcagattc agtagaaatc
     5641 atggaatttg ttcttaattt ggaggatgaa tttcatgtag atgtcccaga tgctgctatt
     5701 gagcattttg aggttctatc tgatattgtt gattttattt ataaagaagt aaaaaaacgt
     5761 tcgtagttta cgggcgtttt tctttgtttt ttcctaaaca accgtaaatt tgttgtgaat
     5821 gcgaatattg tgtgttagaa taaacgaaaa gactagaata tttcacgaaa ggcgaacatt
     5881 ctcatgaaaa cagaccttct ctattcagga aaagccaaag acatctacgc tacggctgac
     5941 agcgaccaga ttgttgcggt ttataaggat caggcgacgg cttttaatgg tggtaagaaa
     6001 gaacagattg tgggcaaggg ccggctcaat aatctgattt catctttgat ttttgaaaaa
     6061 ttgaatgaag ctggtgtccc aacgcatttt atcaagcgtt tgtcggattc ggagcagttg
     6121 aataagaagg tggagattat tcctcttgag gttgttttgc gaaatgtgac agctgggtct
     6181 ttctcaaaac gctttggggt ggaagaaggg ataaccttat ctactcctat cgtggaattt
     6241 tactataaaa aagatgagtt ggacgatcct tttatcaacg atgaacacat tgcctttcta
     6301 gaactggcta gtcaggacca aatcgcctat atcaaggaag aaacaagacg aatcaatgag
     6361 ttcttgaagg acttgtttgc tcagattggg ctgactttgg tggacttcaa actagaattt
     6421 gggattgact cttctgggca aattttattg gcggatgagt tttctcctga taattgtcgt
     6481 ttgtgggatg cggatggcaa ccatctcgac aaggatgttt ttcgtcgggg gctcggggaa
     6541 ttgaccgagg tttacgaggt cgtattggca aaattacagg aagtgaaata aggattggaa
     6601 gatatggcaa agcggatttt tgttgagaag aaggcagcat ttcagatcaa ggcggaggct
     6661 cttcgtaagg agttgactca taatttgcag ttgacaagcc tgtcaagttt gcggttagtg
     6721 caggtttacg atgtcttcaa tcttgaggag gacttgttag agcaggccat caagcatatc
     6781 tttacagagc aggtgacgga caaggttttg tcggatgaag aattaggtct ggaaggtgca
     6841 gtttattttg ctattgaggc tttgcctggg cagtttgacc agcgggctgc cagcagtcag
     6901 gaggcccttc tcttattggg cagtcgtcag gaggtgcgtg tcaatacagg tcagctctat
     6961 attttgaacg gtgatgtgca ggaagaagaa ttagttgcca tcaagaatta tttgcttaat
     7021 cctgtggatt cgcgattcaa ggatatggat gctcctttgg tggctcagga gttttcggta
     7081 tcagatactg tcattccaag cttggacttt tttgatagct acggggtaga ggaatttgcg
     7141 tcttacaagc gtgaggctgg tttggctatg gaagtggaag acctgctctt cattcaggat
     7201 tacttcaagt caattggtcg agtgccaact gagacagaac tcaaggtctt ggatacttac
     7261 tggagtgacc actgccgcca tacgacattt gagacagaac ttaggtctat tgacttttca
     7321 gcctcaaaat ttcaaaagca attgcaggcg acatatgaca agtacttggc gatgcggaca
     7381 gaattaggtc ggacagataa gccacagacg ctcatggata tggcgacgat ttttggtcgt
     7441 tatgagcggg caaatggtcg tctggatgac atggaagtgt cagatgaaat caatgcctgc
     7501 tcggtggaaa ttgaagtgga tgtggatggc gtgaaagagc catggctcct catgttcaag
     7561 aatgaaaccc ataatcaccc tacagaaatc gagccttttg gcggtgccgc aacctgtatc
     7621 ggtggtgcca ttcgcgatcc tttgtcaggt cgttcttatg tttatcaagc catgcggatt
     7681 tcaggtgcag gcgatattac ccaacctctg acagctactc gctcagggaa attgccacag
     7741 caaatcattt caaaaacagc ggcacatggt tattcttcat acggaaacca aatcggtttg
     7801 gcgacaactt atgtacgtga atatttccac ccaggatttg tcgcaaaacg tatggagttg
     7861 ggtgccgtag tcggtgcagc tccaaaggaa aatgtggtcc gtgaaaaacc agttgcaggt
     7921 gatgtggtca tcttgctagg tggtaaaaca ggtcgcgatg gtatcggtgg agcaacagga
     7981 tcgtccaagg tgcagacagt cgagtctgtg gaaacagctg gtgcggaagt ccaaaaagga
     8041 aatgctattg aagaacgtaa aatccaacgc ttattccgca atggtgccgt gactcgcttg
     8101 attaaaaaat ccaatgactt tggtgcagga ggtgtctgcg tagctattgg agaactggca
     8161 gacggtcttg aaattgattt ggataaggtt ccactaaagt atgcaggctt gaacggaacg
     8221 gaaattgcca tttctgaatc acaagagcga atgagcgtgg ttgtccgtcc ggaagacgta
     8281 gatgccttta tcgcagcttg tcgtcaggaa aatatccatg cggttgtcgt agccaaagtg
     8341 actgaaaaac caaacctggt tatgacttgg aatggacaaa ccattgtgga tttggaacgt
     8401 tccttccttg ataccaacgg tgtgcgcgtg gtggtggatg ctaaggtcgt tgacagtcct
     8461 gtcaatctac cagaaacacg tacaacatct gcccaaacac tacgagagga cttgaaagac
     8521 cttctatcag acctcaacca tgctagtcag aaaggtttgc agacgatttt cgactcatct
     8581 gttggtcgtt caaccgtcaa ccacccactc ggaggtcgtc accagctgac tccgacagaa
     8641 agttcggtgc aaaagttgcc tgtccaacag ggtgtgacga caacggcttc ggtcatggct
     8701 cagggctacc atccttacct agcagactgg tcaccttatc acggagcggc ttatgcagtc
     8761 atcgaagcga cagctcgctt ggtggcaaca ggggctaact ggtccaaggc tcgcttctcc
     8821 tatcaggagt atttccaacg aatggataag caggcagagc gttttggtca gccagtagcg
     8881 gctctgctcg gttcgattga ggctcagatt cagcttggcc tgccgtctat cggtggcaag
     8941 gactccatgt ctggtacctt tgaggacttg acagttccgc caaccctggt tgcctttggt
     9001 gtgacaacag cagacagctg caaggttcta tcacctgagt tcaaggcgac tggcgagcac
     9061 atttattacc taccaggcca gattttatca gaagacattg atttcacctt gatcaagtct
     9121 aattttaagg cttttgaaaa atggcagagc gattatgtga ttacggctgc tagtgcagtc
     9181 aagtatggag gagttctaga aagtctagcc cttatgtcct ttggtaacca agtcggagca
     9241 agagttgagc ttgccgactt tgaaaccagc ttgacaggtc aacttggtgg ctttgtcttc
     9301 acatcgcaag aagacattcc agatgctgtg aaaatcggtc aaaccactac agactttaca
     9361 ctggttgtca atggggtcaa cctttctgga caggacttgc aagtagcttt tgagggcaaa
     9421 ctagaagaag tttacccaac agagtttgaa caggcgacgg agttgcagga tgttccagca
     9481 gtcacaagtt cagcggttat aaaagcaaaa gaaaccgttg aagtgcctgt agtttacatt
     9541 ccagttttcc caggcaccaa ctcagaatat gattctgcca aggcctttga acaggctggt
     9601 gcaaaagtca atcttgttcc atttgtgacc ttggatgcag agagcattga aaactcggtt
     9661 gacactatgg ttgacaatat tgctaaggcg aatattctat tctttgcagg tggattctcg
     9721 gctgcggatg aaccagatgg gtctgctaag tttatcgtga ctatcttacg aaacgccaag
     9781 gtccgctctg ctattgacca atttatcgaa aaaagaggcc tcatcatcgg tatctgtaat
     9841 ggtttccagg cccttgtcaa atcgggcttg ttgccgtatg gaaactttga ggaggcgggt
     9901 gataccagtc caaccctctt ctacaacgat gccaaccaac acattgctaa aatggtggaa
     9961 acgcggattg ccaatgtcaa ctcaccgtgg ttggcaggtg tccaagtcgg cgacattcac
    10021 gctatcccag tttcccacgg tgaaggaaaa tttgtagtga cggacgagga atttgctact
    10081 ttgcgtgata atgggcaaat cttcagccaa tacgttgact ttactggtca gccaagcatg
    10141 gattctaagt acaatccaaa tggatccagc catgccattg agggtattac cagtcgcaac
    10201 ggacaaatca tcgggaaaat ggggcattcg gagcgttacg aggacggtct tttccaaaac
    10261 attccaggca agaaagacca aggactcttt gtttcagcgg ttcgctattt tacaggaaaa
    10321 taaatatgac atacgaagtt aaatcactca atgaagaatg tggagttttc ggcatttggg
    10381 gacatccgca ggctgctcag gtgacctatt ttggtctgca tagcttgcag caccgtggac
    10441 aagaaggagc agggatttta gccaatgatg gcggacaatt gtgtcgccat cgcggaacag
    10501 gcctgattgc agaagtcttc aaaaatccag cagatttaga agccttgaca ggaacggctg
    10561 ctattggtca tgtccgctat gcaacttctg gctctgcttc tatcaataat atccagccct
    10621 tcctatttga ttttgcagat atgcaggtgg gtttggcaca taatgggaat ttgaccaacg
    10681 cggtcagttt gaaggctgaa cttgaaaaaa atggttccat tttctcttct tcttctgaca
    10741 ctgagattct catgcacttg attcgccgca gtcacaatcc agactttatg ggaaaaatca
    10801 aggaagccct caatactgtt aaaggtggct ttgcttacct gatcttgtta gaagataaat
    10861 tggttgctgc cttggaccct aatggtttcc gtccactttc aataggcaaa atgaaaaatg
    10921 gtgcctgggt agttgccagc gaaacttgtg cttttgaagt agtgggggct gactgggtgc
    10981 gagatgtgga gcctggtgaa attgtcgtca ttgatgattc aggaattcaa tatgatagct
    11041 atacaagaga tacgcaactg gctgtttgct ctatggagta tgtctatttt gctcgcccag
    11101 attcggtaat tcacggggtc aatgtccaca cggctcgtaa aaacatgggt cgtcgtttgg
    11161 cacaggagtt caaacatgaa gcggatatcg tggttggtgt gccaaactcc tccctatctg
    11221 cggctatggg atttgcagag gaatctggtt tgccaaatga aatggggctg attaaaaacc
    11281 aatataccca gcggaccttt attcaaccaa cccaggaatt gcgggagcag ggtgtgcgca
    11341 tgaagttgtc agctgtttca agtgttgtca aaggcaagcg cgtggtcatg attgacgact
    11401 ctattgttcg cggtacaact agccgccgca ttgtccagct tcttcgtgat gcaggtgcaa
    11461 aagaagtcca tgtggctatt ggcagcccag aactcaagta cccgtgtttc tatggtattg
    11521 atattcagac ccgtcgggag ctgatttcag ccaaccatac cgttgaggaa gtctgtgaga
    11581 ttattggggc agatagtctg acctaccttt ctcttgaagg gatgatagag gccattggta
    11641 tcgaaaccga tgcgccaaaa ggcgggctct gtgtagccta ctttgacgga gaatttccaa
    11701 cgcctctcta tgactatgag gaagaatacc ttcgtagcct agaagagaaa acgagtttct
    11761 acattgaaaa tgtcaagtaa agacagatgt gtcaacgtta cttgacagac ctgtaaactg
    11821 ttgaaaggaa tcaaaatgac aaataaaaat gcctacgccc aatcgggcgt tgacgtcgaa
    11881 gcgggatatg aagttgtcga acgcatcaag aagcacgtag ctcggacaga acgcttgggt
    11941 gttatgggag ccctcggtgg ttttggcggg atgtttgatc taaccaaact ggatgtcaaa
    12001 gagccagtct tggtatctgg gacagacggt gtgggcacca agctcatgct ggctatccag
    12061 tacgacaaac acgacaccat tggtcaagat tgcgtggcta tgtgtgtcaa cgacattatc
    12121 gcagcaggtg cagagccgct ttacttcctt gactacattg cgactggaaa aaatgagcca
    12181 gccaagctag agcaggtagt agcaggtgtg gctgaaggct gtgtccaagc tggttgcgga
    12241 ttgattggcg gtgaaacggc tgaaatgcct ggtatgtacg gcgaggatga ctatgacctg
    12301 gctggctttg ccgtcggcat tgcggagaaa tcccagatta tcgatggcag taaggtccag
    12361 gagggcgaca ttctcctcgg cctagcttcc agcggcatcc actccaacgg ctattccctt
    12421 gtccgacgcg tttttgcaga tgtttctggg gacgctctgt tgccagagct caatggcaga
    12481 gctcttaagg atgtcctatt agagccgaca cgtatctatg tccagcaggt gttgcctctg
    12541 gtaaaagcag gtctggtcaa cggcattgcc catatcacag gcggtggctt catcgaaaat
    12601 gttcctcgta tgtttgctga caaccttgca gctgaaattg aagaagataa gattccagtc
    12661 ctcccaatct ttacagccct tgaaacatac ggccaaatca aacacgaaga aatgtttgaa
    12721 atcttcaata tgggtatcgg aatggtcctg gctgtcagtc cagggaaggt ggagaaagtc
    12781 cgtgaattgg taggcgaaga agtctatgaa atcggccgca ttatcactaa ggaagacaag
    12841 agtgtggtca tcaaatgaaa cgaatagcag tgtttgcatc aggcaacggc tccaatttcc
    12901 aagtcatcgc agaacagttt gaagtagctt ttgtcttttc agaccgcaga aatgcctatg
    12961 tcttggaacg agctgaaaaa ctaggtgtac caacctttgc ttttgaacta aaagagtttg
    13021 cggataagca ggcctacgaa gaagccatta tccaactatt agaccagcac cagattgact
    13081 tggtggtctt ggcaggttat atgaagattg tgggaccaac cctgttggct caatatgaag
    13141 gtcgtatcat caatatccac ccggcttatt tgcctgaatt tccaggagcc catgggattg
    13201 aagacgcttg gaatgcaggt gtggcagaaa gtggtgtgac agttcactgg gttgacagcg
    13261 gtattgacac aggacaaatt atcaaacaag tccgagtgcc caggctggct gatgatatcc
    13321 tagaaacctt tgaagctaga atacatgaag cagagtacca actctatcca gcagttttgg
    13381 aggagttagg ggcagtgaaa aaataaggag aaatcatgac aaaacgcgca ctaattagcg
    13441 tatcagataa aaatggtatt gtagaatttg cccaagaatt gaccaagctt ggctgggaaa
    13501 tcatttcgac aggaggcaca aaggttgctc ttgataatgc tggtgtagcg actatcgcta
    13561 ttgacgatgt gactggtttt cctgagatga tggacggccg tgttaagacc ctgcacccca
    13621 atatccacgg gggtttgctg gctcgtcggg atgtggatag ccacttgcaa gcagccaagg
    13681 accatgaaat tggcctgatt gacttggtag tggtcaacct ttatcctttc aaagagacca
    13741 tcttgcgtcc ggacgtgacc tacgacttgg cggtggagaa catcgacatt ggcggtccgt
    13801 ccatgttgcg ttctgcggct aaaaaccatg ccagcgtgac cgttgtggta gatccggcag
    13861 attatccgac ggttttaggg gaaatagcag agcagggtca gacgacctac ccaacgcgtc
    13921 agcgattggc tgccaaggtt ttccgtcata ccgcagccta cgatgctctt attgcagact
    13981 actttaccaa gcaagtaggc gaagacaagc ctgaaaaatt aaccattact tatgacctca
    14041 atcagcctat gcgttacggt gaaaatccgc agcaaaatgc ggatttctac caaaatgccc
    14101 tgccaacaga ctattctatt gcagcagcta aacagttaaa tggtaaggaa ttgtccttca
    14161 acaacattcg tgatgcggat gcggctatcc gtattatccg tgatttcaag gaccgtccaa
    14221 ctgttgtggc actcaaacat atgaaccctt gtggtatcgg gcaggcagaa actatcgaga
    14281 aggcttggga ttatgcttat gaggctgacc cagtatcgat tttcggaggc attgtcgtgc
    14341 tgaacagaga agtggatgct gcgacggctg aaaagatgca cccaattttc ttagaaatca
    14401 tcatcgcacc gagctactcg gcagaagcgt tagctatttt gaccaataaa aagaaaaatc
    14461 ttcggatttt agaattggct tttgacgcac aggatgcaag cgaagtggaa aaagagttca
    14521 caggtgttgt aggtgggctc ttggtgcagg atcaggacgt ggtggtggaa agcccagcgg
    14581 actggcaggt ggttaccgag cgtcaaccgt ccgagcaaga gtgggcggcc atggagttcg
    14641 cctggaagtc ttccaagtat gtcaagtcca acggcatcat catcaccaat gacaagatga
    14701 ccttgggcgt gggaccgggg caaaccaacc gtgtagcgtc cgtccgtatc gctatcgaac
    14761 aagccaagga tcgtttagag ggagccgttt tggcgtcgga tgccttcttc ccatttgctg
    14821 ataacgtgga agaaattgct gccgcaggta tcaaggctat catccagcca ggtggctctg
    14881 ttcgcgacca agactccatt gacatggcta acaagtacgg cttgaccatg gtctttacag
    14941 gagtcagaca ttttagacat tgagagtttt ggatttagct cacttcgtgt gagctttttt
    15001 attcccgaac attaccctgc tttttctatc aaaacccgtc tatttttgct atactattta
    15061 tagaaaatcc gtttttgagg tgtaaaaaat gaaacttttg gttgtcgggt ctggtggtcg
    15121 tgaacatgct atcgcaaaga aattgttaga gtctgagcag gtagagcagg tctttgttgc
    15181 tcctggaaat gacggaatga ctttagatgg tatcgagtta gtcaatatcg ggatctccga
    15241 acattctgct ataatcaact ttgctaagga aaatgacgtt gcttggactt ttgtgggtcc
    15301 agacgatgct ctggcagcag gaatcgttga tgattttgaa caggcgggac ttaaagcttt
    15361 tggccctagt cgtctagccg cggagctaga gtggtcaaaa gactttgcca aacaaatcat
    15421 ggtcaaatac ggcattccaa cagcagcctt tggcacattt tccaacttcg aagaagccaa
    15481 agcctacatc gaagagcagg gtgcaccaat cgtggtcaag gcggacggct tggcactggg
    15541 caagggcgtg gtcgtggcgg aaaccgtcga gcaggcggtc gaagcggcac gggagatgct
    15601 cttggacaac aagttcggcg actcgggtgc ccgcgtggtc atcgaggagt tcttggcggg
    15661 tgaggagttt tccctctttg ctctggtcaa tggcgaccaa ttttacattc tgccgacagc
    15721 ccaggaccac aagcgtgcct ttgacggcga ccaaggtccc aacacaggtg gtatgggggc
    15781 ttacgctcct gttccccacc tgcctcaaag cgtggtggac acagcggttg acaccattgt
    15841 caagccgatt cttgagggca tgattgcgga cggccggtct tatctgggcg tgctctatgc
    15901 tggcttgatt ctgaccgacc aaggtcccaa ggtcatcgag ttcaacgccc gttttggcga
    15961 cccagaaacc cagattatcc tgcctcgcct gacctctgac tttgctcaga acatcgacga
    16021 catcctccac aaacgcccga cacagctgac ttggctggat agtggcgtga cgctgggtgt
    16081 tgtcgtggca tcaaacggct accctctgga ctacgaaaaa ggcgtagagt tgccagcaaa
    16141 gaccgagggc gacatcacga cctactatgc aggggctcgt tttgcggaaa atagcagagc
    16201 actgctttca aacggcggtc gggtttatat gctagtcacc acagcagaca ccgtccaaga
    16261 cgcccaagaa aaaatttact cggagctgaa aaatcaagat accacaggcc tcttttatcg
    16321 gacagatatt ggaagtaagg cagtaaaata agggataaag aaaaggaaag acaagcatga
    16381 acattccaat ttccatcatc atgggttcta gttccgactg gaaaaccatg aaaaaagcag
    16441 ccgatatgct ggacaaattt ggcgtagcct atgaaaagaa agtggtctct gcccaccgca
    16501 ccccagacct catgttccgt cacgccgaag aagcgcgtgg tcatggcttc aaggtcatta
    16561 tcgcaggagc gggcggtgcg gctcatttgc caggtatggt agcagccaag acaaccctac
    16621 ctgtcatcgg tgttcctgtc caatcccgtg ccctcagcgg tgtggattcg ctctattcta
    16681 ttgtgcagat gccgggcggc gtgcctgttg cgactatggc gatcggcgaa gcaggtgcca
    16741 ccaacgcagc cctgacagct cttcgcattc tctccattga agatcaaacc attgcggctc
    16801 agctggcaga ttttgccaag gaacaggaaa aaattgcgga ggcgatgaca gatgacctca
    16861 tctaagacaa tcggaattat cggcggcggt cagctgggtc agatgatggc tatttccgct
    16921 atttacatgg gccacaaggt gatcacgctg gatcctgcgg cggactgccc agcctccaag
    16981 gtcagcgagg tcatcgtcgc tccctatcac gatgtggcgg ccctcaaaca gctggcggag
    17041 cggtgcgatg tcctgaccta tgagtttgaa aatgttgatg ccgacggact ggacgcggtc
    17101 attaaggacg gccagctccc tcaagggact gacctcctcc gtatttccca aaaccgcatt
    17161 tttgagaagg attttttggc aaaaaaagct ggcgtgcaag tcgcccccta caaagtcgtc
    17221 acatctagcc tagacctaga aggactggac ctcagcaaaa actatgtctt aaagacagcc
    17281 actgggggct atgacggaca tggccagaag gtcattcgag aagaggcgga cttggtagaa
    17341 gctagtcagt tagctaactc tgccgagtgt gttttggaag agtttgtgaa tttcgacctg
    17401 gaaatctccg tccttgtatc tggcaatggc tccgactaca ccgtctttcc tgtgcaggaa
    17461 aatatccacc gcaataatat cctttacaaa accatcgtgc ctgcccgtat ttttgacgaa
    17521 cttgctgaaa aagccaaaac catggccctg caaatcgccg acaagctcca tttagtaggc
    17581 accctctgtg ttgaaatgtt tgtggcaggg caagaaattc ttgtgaatga aatcgctcct
    17641 cgcccgcaca attcaggaca ttattcgatt gaagcctgtg atttttcaca gtttgacacc
    17701 catatacgag gcattttagg ggagcccctg ccccctatcc gcctgctttc accagcagtt
    17761 atgattaacg ttttgggaca agacatggaa acagtccaaa cctttcttca agaaaaccct
    17821 accgcccatc cccactttta tggtaaacta gaagcgaagc acaatcgcaa aatgggacac
    17881 gtgacggtgt tgggggaaga tgcggaaagt gtggaggagt ttgaaaatta agattgcttt
    17941 ctgatttttt agttattaaa aagaggttta tgacatgcca ttaccacaaa aaattcaaga
    18001 agagattaaa agatattgca ataatcactt gcctaataat gactggtatg agaaagagtt
    18061 tgattttata catgatgtga gtctgaagaa tagaattatt agagagttta aatcaattcg
    18121 gtacgcttac aagttatacg aagggataac ggctgaggag gaacatttaa tttttgaaat
    18181 tcgcagtcaa attttagcat atgcctctat atatgaagca gtagtagagt acgttttaga
    18241 gacatactat agtgatactc aagtttatga tgatttggtc catcaaaata atgtgatgac
    18301 aaaaattgac ataccagaag aaaagaggaa aaaattagaa agagaattaa tccatctagt
    18361 agataatggt acaaaaaata tagaaataca tacatttttt tatcaaagaa agaggaaggc
    18421 atcaacttca attcgttttg atgcaaagtg tcgtgcagca gaggaattaa atataatttc
    18481 aaaaatttat caaaaaggaa ataaagttgt tgcagattta ccatccgata ttattgaaat
    18541 ttatgagtac aggaatgcaa tccatttgat agccgagcaa cgtaaaaaca ttgactatga
    18601 attagaactt agtcaacgag cgtatagaag aatgaaacct t
//
LOCUS       DBNFCO010000042        18521 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.042, whole genome shotgun sequence.
ACCESSION   DBNFCO010000042 DBNFCO010000000
VERSION     DBNFCO010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 18521)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18521)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18521
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.042"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            205..603
                     /gene="spx"
                     /locus_tag="AC1PIV_001192"
     CDS             205..603
                     /gene="spx"
                     /locus_tag="AC1PIV_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HIP6612217.1"
                     /translation="MIKIYTVSSCTSCKKAKNWLNAHQLSYNEHNLAKEAITKEEILN
                     ILTKTENGIASIVSSKNRYAKSLDFDIEELSVNEVIDLITSNPRILKSPILIDEKRLQ
                     VGYKEDDIRAFLPRAVRNVENAQARMRAAL"
     gene            703..969
                     /locus_tag="AC1PIV_001193"
     CDS             703..969
                     /locus_tag="AC1PIV_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002885737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HIP6612218.1"
                     /translation="MGFTEETVRFRLDDTDKQEISKTLTSVYRSLEEKGYNPINQIIG
                     YVLSGDPAYIPRYNDARNQIRKHERDEIIEELVRYYLKGNGIDL"
     gene            969..1388
                     /gene="ruvX"
                     /locus_tag="AC1PIV_001194"
     CDS             969..1388
                     /gene="ruvX"
                     /locus_tag="AC1PIV_001194"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HIP6612219.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIPIDEEKGEFGLER
                     LTELVEQYKVDKFVVGLPKNMNNTSGPRVEASQAYGDLLTERYKLPVDYQDERLTTVA
                     AERMLIEQADISRGKRKKVIDKLAAQLILQNYLDRTF"
     gene            1400..1720
                     /locus_tag="AC1PIV_001195"
     CDS             1400..1720
                     /locus_tag="AC1PIV_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HIP6612220.1"
                     /translation="MAHHHDHEHDHNHDERELITLVDDQGNETLFEILLTIDGQEEFG
                     KNYVLLIPASAEEDENGEVEIQAYSYIENENGTEGDLQPIPEDATAEWDMIEEVFNSF
                     MEEE"
     gene            1928..2506
                     /locus_tag="AC1PIV_001196"
     CDS             1928..2506
                     /locus_tag="AC1PIV_001196"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012774895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HIP6612221.1"
                     /translation="MKDSFTERSKKLSEELERCLLADKNILVILDIMDRLNLSDCWLC
                     AGTIRNFIWNQYSFDEETDVDLVFFDENISYEETMEIESNLYQNYPAYQWELKNQVYM
                     HIHSPNTKPYQSSRDAIEKFPERCTAIGICRTERNKLEIFAPFGLDDIYAYQVRPTPH
                     FLADPNRMELYRQRILKKQWKKRWLSLTVKEI"
     gene            3169..3477
                     /gene="rpsJ"
                     /locus_tag="AC1PIV_001197"
     CDS             3169..3477
                     /gene="rpsJ"
                     /locus_tag="AC1PIV_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HIP6612222.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVETATRTGAQVAGPVPLPT
                     ERSFYTIIRATHKYKDSREQFEMRTHKRLIDIINPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            3574..4200
                     /gene="rplC"
                     /locus_tag="AC1PIV_001198"
     CDS             3574..4200
                     /gene="rplC"
                     /locus_tag="AC1PIV_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HIP6612223.1"
                     /translation="MTKGILGKKVGMTQIFTESGEFIPVTVIEATPNVVLQVKTVETD
                     GYAAVQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNIEGLEVGQEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGNRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            4225..4848
                     /gene="rplD"
                     /locus_tag="AC1PIV_001199"
     CDS             4225..4848
                     /gene="rplD"
                     /locus_tag="AC1PIV_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HIP6612224.1"
                     /translation="MANVTLFDQTGKQAGEVVLNDAIFGIEPNQAVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYAYKLP
                     QKVRRLALKSVYSEKVAENKFVAVNSLEFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNIPGVKVATATTASVLDIANADKLLVTQAAISKIEEVLA"
     gene            4848..5147
                     /locus_tag="AC1PIV_001200"
     CDS             4848..5147
                     /locus_tag="AC1PIV_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HIP6612225.1"
                     /translation="MNLYDVIKKPVITESSMGQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKTKRVGRYVGRTNKVKKAIITLAADSKAIELFATADAE"
     gene            5165..5998
                     /gene="rplB"
                     /locus_tag="AC1PIV_001201"
     CDS             5165..5998
                     /gene="rplB"
                     /locus_tag="AC1PIV_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HIP6612226.1"
                     /translation="MGIKVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDGVEAIVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTVVHNIELKPGRGGELVRAAGA
                     SAQVLGQEGKYVLVRLQSGEVRMILGTCRATVGTVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNQ
                     K"
     gene            6249..6530
                     /gene="rpsS"
                     /locus_tag="AC1PIV_001202"
     CDS             6249..6530
                     /gene="rpsS"
                     /locus_tag="AC1PIV_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HIP6612227.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            6548..6892
                     /gene="rplV"
                     /locus_tag="AC1PIV_001203"
     CDS             6548..6892
                     /gene="rplV"
                     /locus_tag="AC1PIV_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HIP6612228.1"
                     /translation="MAEITSAKATARTVRVSPRKSRLVLDNIRGKSVADAIAILKFTP
                     NKAAGIIEGVLNSAIANAENNFGLEKANLVVSEAFANEGPTLKRFRPRAKGSASPINK
                     RTAHITVVVAEK"
     gene            6905..7558
                     /gene="rpsC"
                     /locus_tag="AC1PIV_001204"
     CDS             6905..7558
                     /gene="rpsC"
                     /locus_tag="AC1PIV_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HIP6612229.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRNFIKK
                     ELADASTSTIEIERAVNKVIVSIHTAKPGMVIGKAGSNVDALRAQLNKLTGKQVHINI
                     IEIKQPDLDAHLVGESIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEALTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            7562..7975
                     /gene="rplP"
                     /locus_tag="AC1PIV_001205"
     CDS             7562..7975
                     /gene="rplP"
                     /locus_tag="AC1PIV_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HIP6612230.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKQVDFGQYGLQATTSSWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEVAGVSEEIAREAFRLAGHKLPVKVKFVKREAE"
     gene            7985..8191
                     /gene="rpmC"
                     /locus_tag="AC1PIV_001206"
     CDS             7985..8191
                     /gene="rpmC"
                     /locus_tag="AC1PIV_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HIP6612231.1"
                     /translation="MKLQEIKDFVKELRGLSQEELAKKENELKKELFELRFQAAAGQL
                     EQTARLNEVKKQIARIKTVQSETK"
     gene            8215..8475
                     /gene="rpsQ"
                     /locus_tag="AC1PIV_001207"
     CDS             8215..8475
                     /gene="rpsQ"
                     /locus_tag="AC1PIV_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HIP6612232.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            8500..8868
                     /gene="rplN"
                     /locus_tag="AC1PIV_001208"
     CDS             8500..8868
                     /gene="rplN"
                     /locus_tag="AC1PIV_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HIP6612233.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDIIVASVK
                     QATPGGAVKKGDVVKAVIVRTKTGARRADGSYIKFDENAAVIIREDKNPRGTRIFGPV
                     ARELRDGGFMKIVSLAPEVL"
     gene            9007..9312
                     /gene="rplX"
                     /locus_tag="AC1PIV_001209"
     CDS             9007..9312
                     /gene="rplX"
                     /locus_tag="AC1PIV_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HIP6612234.1"
                     /translation="MFVKKGDKVRVIAGKDKGVEAVVVTALPKVNKVIVEGVNIVKKH
                     QKSNSENPQGAIVEKEAPIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            9336..9878
                     /gene="rplE"
                     /locus_tag="AC1PIV_001210"
     CDS             9336..9878
                     /gene="rplE"
                     /locus_tag="AC1PIV_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HIP6612235.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGDA
                     VSNAKNLEKAAQELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVTVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGMDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            9893..10078
                     /locus_tag="AC1PIV_001211"
     CDS             9893..10078
                     /locus_tag="AC1PIV_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HIP6612236.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCEKCGRPHSVYRKFKLCRVCF
                     RDLAYLGQIPGVTKASW"
     gene            10415..10813
                     /gene="rpsH"
                     /locus_tag="AC1PIV_001212"
     CDS             10415..10813
                     /gene="rpsH"
                     /locus_tag="AC1PIV_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HIP6612237.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIATILKNEG
                     FVKNVEFIEDDKQGIIRVFLKYGPNGEKVITNLKRVSKPGLRVYSKREDIPKVLNGLG
                     IAIISTSEGLLTDKQARQKNVGGEVIAYVW"
     gene            11279..11815
                     /gene="rplF"
                     /locus_tag="AC1PIV_001213"
     CDS             11279..11815
                     /gene="rplF"
                     /locus_tag="AC1PIV_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HIP6612238.1"
                     /translation="MSRIGNKVITLPAGVELAQNNGVVTVKGPKGELTREFPTAIEIR
                     VEGAEVTLHRPNDSKEMKTIHGTSRANLNNMVVGVSEGFKKELEMRGVGYRAQLAGNK
                     LTLAVGKSHPDEVVAPEGITFEVPTPTQIVVSGINKEVVGQTAAYIRSLRAPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            11904..12260
                     /gene="rplR"
                     /locus_tag="AC1PIV_001214"
     CDS             11904..12260
                     /gene="rplR"
                     /locus_tag="AC1PIV_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HIP6612239.1"
                     /translation="MISKPDKNKIRQKRHRRVRGKISGTAARPRLNIFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVVVGKLVAERAVAKGISEVVFDRGGYLYHG
                     RVKALAESARENGLKF"
     gene            12279..12773
                     /gene="rpsE"
                     /locus_tag="AC1PIV_001215"
     CDS             12279..12773
                     /gene="rpsE"
                     /locus_tag="AC1PIV_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HIP6612240.1"
                     /translation="MAFKDNAVEIEERVVAINRVTKVVKGGRRLRFAALVVVGDRNGR
                     VGFGTGKAQEVPEAIRKAVESAKKNMIEVPMVGTTIPHEVRSEFGGARVLLKPASEGS
                     GVAAGGATRAVIELAGIADVTSKSLGSNTPINIVRATVEGLKQLKRAEEVAALRGISV
                     SDLA"
     gene            12788..12970
                     /gene="rpmD"
                     /locus_tag="AC1PIV_001216"
     CDS             12788..12970
                     /gene="rpmD"
                     /locus_tag="AC1PIV_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HIP6612241.1"
                     /translation="MAQIKITLTKSPIGRKPEQRKTVVALGLGKLNSSVVKEDNPAIL
                     GMVNAISHLVTVEEVK"
     gene            13106..13546
                     /gene="rplO"
                     /locus_tag="AC1PIV_001217"
     CDS             13106..13546
                     /gene="rplO"
                     /locus_tag="AC1PIV_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HIP6612242.1"
                     /translation="MKLHELQPATGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRPGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNAFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITSKGGSVEVI"
     gene            13560..14870
                     /gene="secY"
                     /locus_tag="AC1PIV_001218"
     CDS             13560..14870
                     /gene="secY"
                     /locus_tag="AC1PIV_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HIP6612243.1"
                     /translation="MFFKLLKDALKVKLVRSKILFTIFILFVFRVGTHITVPGVNAKS
                     LEALSNLPFLNMLSLVSGNAMRNFSVFALGVSPYITASIIVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYISLVLAFVQSIGITAGFNALSGAKLTNMPLNWQTYLLIGAILTT
                     GSIIVTWLGEQISEKGYGNGTSMIIFAGIISSLPGTFHEIYIDRFVNIESSRLGESAI
                     FVAALVVLIFFVVYFTTFVQQAEYKLPIQYTKRAQGAPSSSYLPLKLNPAGVIPVIFA
                     GSITAVPTSLIQYFASQNKSAGWLLTVQEYFDYSTAKGMIVYAGLIIAFTFFYTFVQV
                     NPEKTAESLQKSAAYIHGVRPGNGTEQFLSKLLTRLAVIGALFLSFVALLPILAQNLF
                     GLSSSIAFLGTSLIIVISTSIEGIKQLEGYLLKRKYVGFLEITE"
     gene            14964..15605
                     /locus_tag="AC1PIV_001219"
     CDS             14964..15605
                     /locus_tag="AC1PIV_001219"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HIP6612244.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEKFNVAHISTGDMFRAAMANQTE
                     MGILAKSYIDKGDLVPDEVTNGIVKERLVQDDIKEKGFLLDGYPRTIEQAHALDENLA
                     DLGIELQGVINIEIDPSKLVERLSGRIIHKETGETFHKVFNPPVGDYKEEDFYQREDD
                     KPESVKRRLEVNIAQGQPIIDHYRAKGLVHDIEGDQDIDLVFQAIDTVLSKLQ"
     gene            15727..15945
                     /gene="infA"
                     /locus_tag="AC1PIV_001220"
     CDS             15727..15945
                     /gene="infA"
                     /locus_tag="AC1PIV_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HIP6612245.1"
                     /translation="MAKEDVIEIEGKVVDTMPNAMFTVELENGHQVLATVSGKIRKNY
                     IRILVGDRVTVELSPYDLTRGRITYRFK"
     gene            15970..16086
                     /gene="rpmJ"
                     /locus_tag="AC1PIV_001221"
     CDS             15970..16086
                     /gene="rpmJ"
                     /locus_tag="AC1PIV_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HIP6612246.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            16106..16471
                     /gene="rpsM"
                     /locus_tag="AC1PIV_001222"
     CDS             16106..16471
                     /gene="rpsM"
                     /locus_tag="AC1PIV_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HIP6612247.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VKDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            16489..16872
                     /gene="rpsK"
                     /locus_tag="AC1PIV_001223"
     CDS             16489..16872
                     /gene="rpsK"
                     /locus_tag="AC1PIV_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HIP6612248.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKTVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            16917..17855
                     /locus_tag="AC1PIV_001224"
     CDS             16917..17855
                     /locus_tag="AC1PIV_001224"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HIP6612249.1"
                     /translation="MIEFEKPTITKIDENKDYGRFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSIKIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKKIELDVVGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIADGATFKAVLTVNSGRGYVPAEDNKKDDAPVG
                     TLAVDSIYTPVKKVNYQVEPARVGSNDGFDKLTLEINTNGTIIPEDALGLSARILMEH
                     LGLFTDLTEVAKSAEVMKEAEVASDDRMLDRTIEELDLSVRSYNCLKRAGINTVFDLT
                     EKTEPEMMKVRNLGRKSLEEVKVKLADLGLGLKKDK"
     gene            17870..18256
                     /gene="rplQ"
                     /locus_tag="AC1PIV_001225"
     CDS             17870..18256
                     /gene="rplQ"
                     /locus_tag="AC1PIV_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HIP6612250.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSATALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
BASE COUNT         5953 a         3462 c         4008 g         5098 t
ORIGIN      
        1 ttgatgcata tctgttatag gtgtgtatga agttgtttag tataagaacg aaaaagtctg
       61 gagattccag gcttttttct aataaaaacc gaatttttac cccaaaattt aaagtttttt
      121 taaaaaatag gtctgcagac cgagggaatt tatgatataa tagtctataa tgtgcttaat
      181 aaaatgtagc aaaggagtga ctacatgatt aaaatttata ctgtatctag ttgtacttct
      241 tgtaagaaag cgaaaaattg gttaaatgct caccaattat cttataatga gcataatctt
      301 gcgaaggaag ccattactaa ggaagaaatc ctaaacatct taacaaaaac agagaatggt
      361 attgcaagta tcgtatcgtc aaaaaaccgt tatgcaaaga gtctggactt cgatattgaa
      421 gagttgagtg tgaacgaggt cattgattta attacctcta acccacgtat tttgaagagt
      481 ccaatcttga ttgatgagaa acgacttcaa gtgggctata aagaagatga tatacgcgct
      541 ttcttgccac gtgcagtgcg caatgttgaa aatgctcaag ctcgtatgag agcagctcta
      601 taagatgtac aaaaggactc ttttggggtt ctttttgcgc attttttgag aataattaaa
      661 atttgtgata taatgtaaaa aatagggaaa gaaggtgtaa gtatgggatt taccgaagaa
      721 accgttcgtt ttcgcctaga tgatacagat aaacaagaaa tcagcaagac attgactagt
      781 gtttatcgtt cgctggagga aaagggctat aatccgatta accaaatcat tggctatgta
      841 ttaagtgggg accctgctta tattcctcgc tataatgatg cccgcaatca gattcgtaag
      901 catgaacgag atgaaatcat tgaagaattg gtgcgctact atttgaaagg gaatgggatt
      961 gacctctaat gagaataatg ggattagacg tcggttccaa gacagttggt gtagccattt
     1021 cagatccgtt aggtttcacg gcccaagggt tggaaatcat cccaatcgat gaagaaaagg
     1081 gcgaattcgg tctggagcgt ttgaccgaac ttgtagaaca gtacaaggtt gataaatttg
     1141 ttgtaggctt gccgaagaat atgaataata ctagtggtcc acgtgtggaa gctagtcaag
     1201 cttacggtga tttattgact gagcgttaca aacttccagt tgattatcag gatgaacgtt
     1261 taacaactgt tgcagcagaa cggatgctga ttgagcaagc ggatatcagc cgaggaaaac
     1321 gcaagaaagt tatcgataaa ttagcagctc agctgatttt acaaaattat ttagatagaa
     1381 cattttaaag gagattctaa tggcacatca tcatgaccat gaacacgacc acaaccacga
     1441 cgaacgtgaa ttgattactt tggtagacga ccaaggtaac gaaacacttt ttgaaatctt
     1501 attgacgatt gacggtcaag aagagtttgg taagaactat gttctcttga ttcctgcaag
     1561 tgcagaagaa gatgagaacg gagaagttga aatccaagcc tactcataca ttgagaatga
     1621 gaatggcaca gaaggcgatt tgcaacctat cccagaagac gcaacagcag aatgggatat
     1681 gattgaagaa gtcttcaaca gctttatgga agaggaataa aaaggtccgg gtggaccttt
     1741 ttatcatgag catgaaaaca agaaagcgaa ttaaggtcca gtggaccttt ttatcatgag
     1801 ctgaaaatca aagagcgaat taaggtccgg tggagtgaag cagtctgggg gagactgttt
     1861 cagcccgagt taagaaatag caaggggagg aatgaatcat gagccagaaa atcaaaaggg
     1921 aggccagatg aaagatagtt ttacagaaag aagtaagaag ctgagtgagg aattagagag
     1981 gtgtctactg gctgataaaa atattttggt catattagac ataatggata gactgaattt
     2041 atcagattgc tggctctgtg cgggaactat ccgtaatttc atttggaatc aatacagttt
     2101 tgatgaagaa acagatgttg atcttgtgtt ttttgatgaa aatatttctt atgaagagac
     2161 aatggaaata gaaagcaatt tatatcaaaa ctatccagcc tatcaatggg aattaaaaaa
     2221 tcaagtgtat atgcatatcc atagtccgaa tactaaaccg tatcaatcat caagggatgc
     2281 gattgaaaaa tttccagaaa gatgcacagc gataggtatt tgtcgaacag aaagaaataa
     2341 attagaaata tttgctcctt ttggattgga tgacatttat gcttaccaag tacggccaac
     2401 accacatttc ttagcggatc ctaatcgcat ggaattgtat cgacaaagaa ttcttaagaa
     2461 acagtggaaa aagaggtggc tatcgctaac agtaaaagag atttaactcc caccaagtaa
     2521 gtaggccaaa aacagtattt tttataaact aaaacaatca actacgggag attatgttat
     2581 ggaatttgaa acggtttgtt tgaaggttag aaacttaggt aggctatatt gctacttcaa
     2641 agttaaattt agaacccata tcgaggctat aattcgtaaa caggaaagtc aaaaatgtaa
     2701 atttgatcgt ctcctccatg aagatattca tagtttgatt caatcaccga gcttgggtaa
     2761 tgatgagttg ctgatgttat ggggtctcct gagagattat cgaaaaaatt taatcaatga
     2821 ccgacttgaa aatatgaaaa attgataagc ggacagagtt ttactggcag tcaaaaaaat
     2881 aattcgagac ttacaaggat atttgaaaaa aaaacgttga tagttaactc aaataaaaaa
     2941 taagtaatga agaatcctga aataaaagtt ttgggatttt ttgaattttt gagtaaaaac
     3001 tcttgcaatg gcaagtggaa tctggtagaa tgttctagtg ccgtaaaaat tacggctgta
     3061 gctttgatgc aagaggttgc gacacgctcg gttgcattgc cacgcaacac gtgttggttt
     3121 tcttgtggag ctagcctatt atgttaaata gacgaaaagg agaaaaagat ggcaaacaaa
     3181 aaaattcgca tccgcttgaa agcgtacgaa caccgtacac ttgatacagc agctgcaaaa
     3241 atcgttgaaa ctgcaacacg tacaggtgct caagtagcag gtccagttcc acttccaaca
     3301 gaacgtagct tctacacaat catccgtgcg actcacaagt acaaagattc tcgtgagcag
     3361 ttcgaaatgc gtacacacaa acgtttgatc gacatcatca acccaactca aaaaacagtt
     3421 gacgctttga tgaaattgga tcttccaagt ggtgtaaacg tagaaattaa attgtaatca
     3481 agtcgcgagc aaaactcaga atcttgattt gagcatgaaa aacgctcgtt aaaaactttt
     3541 taaatacaaa ataagaaaag gaatattttt ctcatgacaa aaggaatctt agggaaaaaa
     3601 gtgggaatga ctcaaatctt cactgaatct ggtgaattta tccctgttac tgtcatcgaa
     3661 gcaactccaa acgttgttct tcaagtgaaa acagttgaaa ctgatggtta tgcagcagtt
     3721 caagttggtt ttgatgacaa acgtgaagta ttgagcaaca aacctgccaa aggccatgta
     3781 gctaaagcta acacagctcc taagcgcttc attcgtgaat tcaaaaacat tgaaggcttg
     3841 gaagttggac aagaaattac agttgaaact ttcgcagctg gtgatgttgt tgatgtaact
     3901 ggtacatcta aaggtaaagg tttccaaggt gttatcaaac gccatggtca atcacgtggt
     3961 cctatggctc acggttctcg ttaccaccgt cgtccaggtt ctatgggtcc tgttgcacct
     4021 aaccgtgtat tcaaaggtaa aaaccttgca ggtcgtatgg gcggcaaccg tgtaacaatt
     4081 caaaaccttg aagttgtaca agttgttcca gaaaagaacg ttatccttat caaaggtaac
     4141 gtaccaggtg ctaagaaatc tcttatcact atcaagtcag cagtcaaagc tggtaaataa
     4201 taaggaaagg ggaaatcagt cgaaatggca aacgtaacat tatttgacca aactggtaaa
     4261 caagctggtg aagtagttct taacgatgcg atctttggta tcgagccaaa ccaagcagtt
     4321 gtatttgatg tgatcatcag ccaacgtgct agccttcgtc aaggtactca cgcagttaaa
     4381 aaccgttcag cagtctcagg tggcggacgc aaaccatggc gtcaaaaagg aactggacgt
     4441 gctcgtcaag gttctatccg ttcaccacaa tggcgtggcg gtggcgtagt cttcggacca
     4501 actccacgtt catacgcgta caaacttcca caaaaagttc gtcgcttggc acttaaatct
     4561 gtttactcag aaaaagttgc tgaaaacaaa tttgtagctg ttaactcact tgaattcaca
     4621 gctccaaaaa ctgctgaatt tgcaaaagta cttgcagcat tgagcattga ttctaaagtc
     4681 cttgttattc ttgaagaagg caacgaattc gcagctctct ctgctcgtaa catcccagga
     4741 gttaaagttg caactgcaac aactgcaagt gtacttgaca tcgcaaatgc agacaaactt
     4801 cttgtaactc aagcagctat ctctaaaatt gaggaggttc ttgcataatg aatttgtatg
     4861 atgttatcaa aaaacctgtc atcacagaaa gctcaatggg ccaactcgaa gcaggcaagt
     4921 atgtatttga agttgacact cgtgcacaca aactcttgat caagcaagct gttgaagctg
     4981 cattcgaggg tgttaaagtt gcaaatgtta acacaatcaa cgtgaaacct aaaacaaaac
     5041 gcgtaggtcg ttatgtaggt cgcacaaaca aagtgaaaaa agcaatcatc acattggctg
     5101 ctgattcaaa agcgatcgaa ttgttcgcta cagctgacgc tgaataatca aaggaggaat
     5161 taacgtgggt attaaagttt ataaaccaac gacaaatggc cgtcgtaaca tgacttcttt
     5221 ggacttcgct gaaatcacaa caagcactcc agaaaaaagc ttgcttgttg ctttgaagag
     5281 caaagctggt cgtaacaaca acggtcgcat cactgttcgt caccaaggtg gcggtcacaa
     5341 acgtttctac cgtttggtag acttcaaacg taacaaagat ggcgttgaag caatcgttaa
     5401 aactatcgaa tacgatccaa accgttcagc aaacatcgct cttgtacact acacagacgg
     5461 tgttaaagct tacatcattg ctcctaaagg tcttgaagtt ggtcaacgca tcgtttcagg
     5521 tccagaagca gatatcaaag ttggtaacgc acttccactt gcaaacatcc cagtcggtac
     5581 tgttgttcac aacatcgagt tgaaaccagg tcgcggtggt gagttggttc gtgctgctgg
     5641 tgcatctgca caggttcttg gtcaagaagg taaatacgtt cttgttcgcc ttcaatcagg
     5701 tgaagttcgt atgatccttg gtacttgccg tgctactgtt ggcactgtag gtaacgaaca
     5761 acatggcctt gttaaccttg gtaaagcagg tcgtagccgt tggaaaggta tccgtccaac
     5821 agttcgcggt tctgtaatga accctaacga tcacccacac ggtggtggtg aaggtaaagc
     5881 accagttggt cgtaaagcac catctacacc atggggtaaa ccagctcttg gtttgaaaac
     5941 tcgtaacaag aaagctaaat ctgacaaact tatcgttcgt cgtcgcaacc aaaaataatc
     6001 tattcttagt tacatagcat tctatatcat ccgccaactc ggtagggttt gttatggact
     6061 gactattcca gcacctcagt ttgattgaaa tgccagtttg acgcagtggt tgattgcagt
     6121 ttctagtagc ttagctacgt cgaaacttct aatcaactgt gcgggggcag gacaacgaac
     6181 acggtaactg gggttctgtc catctcccaa gccgctgtgg tacatatttt aaaggagaaa
     6241 acactaaaat gggacgtagt cttaaaaaag gacctttcgt cgatgagcat ttgatgaaaa
     6301 aagttgaagc tcaagcaaat gacgaaaaga aaaaagtaat taaaacttgg tcacgtcgtt
     6361 caacgatctt cccaagtttc atcggttata caatcgcagt ttacgatgga cgtaaacacg
     6421 tacctgtata cattcaagaa gacatggtag gtcacaaact tggtgaattt gcaccaactc
     6481 gtacttacaa aggtcatgct gctgacgaca agaaaactcg tcgtaaataa tttaggagga
     6541 aaacacaatg gcagaaatta cttcagctaa agcaactgct cgcacagtac gtgtttcacc
     6601 tcgtaaatca cgtcttgtct tggataacat ccgtggcaaa agcgtagcag acgcaatcgc
     6661 aatcttgaaa ttcacaccaa acaaagctgc aggcattatc gagggagttt tgaactcagc
     6721 aatcgctaac gctgaaaaca actttggttt ggaaaaagct aacttggtag tcagcgaagc
     6781 attcgcaaac gaaggaccaa cgttgaaacg tttccgtcca cgtgcgaaag gttctgcttc
     6841 accaattaac aaacgcacag ctcatatcac tgtagttgtg gcagagaaat aaggaggtaa
     6901 aaacgtgggt caaaaagtac atccaattgg tatgcgtgtt ggcatcatcc gtgattggga
     6961 tgctaaatgg tatgctgaaa aagaatacgc ggattacctt catgaagatc ttgcaatccg
     7021 caactttatc aaaaaagaat tggctgatgc gtcaacatca acaatcgaaa tcgaacgtgc
     7081 tgtaaataaa gtaatcgttt ctatccacac tgctaaacca ggtatggtta tcggtaaagc
     7141 tggtagcaac gttgatgcgc ttcgtgctca attgaacaaa ttgactggta agcaagtaca
     7201 catcaacatc atcgaaatca aacaacctga tttggatgca caccttgttg gtgagtcaat
     7261 cgctcgtcaa ttggagcaac gtgtggcatt ccgccgtgct caaaaacaag ctatccaacg
     7321 tgcaatgcgc gctggtgcaa aaggtatcaa aacacaagtt tctggtcgtt tgaacggtgc
     7381 ggatattgcc cgtgcagaag gctactcaga aggaactgtt cctcttcata cacttcgtgc
     7441 ggatatcgac tacgcttggg aagaagcttt gacaacttac ggtaaacttg gtgttaaagt
     7501 atggatctac cgtggtgaag ttcttccagc tcgtaaaaac actaaaggag gtaaataaca
     7561 aatgttagta cctaaacgtg taaaacaccg tcgtgaattc cgtggaaaaa tgcgcggtga
     7621 agctaaaggt ggaaaacaag tagactttgg tcaatacggt cttcaagcaa ctactagctc
     7681 atggattaca aaccgccaaa tcgaagctgc ccgtatcgct atgacgcgtt acatgaaacg
     7741 tggtggtaaa gtttggatta agatcttccc acacaaatca tacactgcta aagctatcgg
     7801 tgtacgtatg ggttctggta aaggtgctcc tgaaggttgg gtagctccag ttaaacgcgg
     7861 taaggttatg tttgaagtag ctggcgtttc tgaagaaatc gctcgcgaag cattccgcct
     7921 tgctggtcac aaattgccag ttaaagttaa attcgtaaaa cgtgaagcag aataaggaga
     7981 agacatgaaa cttcaagaaa ttaaagattt tgtaaaagaa cttcgtggcc tttctcaaga
     8041 agaacttgct aagaaagaaa acgaattgaa gaaagaactc ttcgaacttc gtttccaagc
     8101 tgctgctggt caacttgagc aaactgctcg tttgaacgaa gtgaagaaac aaattgcgcg
     8161 tatcaaaact gtgcaatctg aaactaaata atagattggg aaaggagaat ttcaatggaa
     8221 cgcaataatc gtaaagttct tgttggacgc gtagtatctg acaaaatgga caaaacaatc
     8281 acagttgtag ttgaaactaa acgtaaccac ccagtctatg gtaaacgtat taactactct
     8341 aaaaagtaca aagctcatga tgaaaacaat gttgctaaag aaggcgatat cgttcgtatc
     8401 atggaaactc gcccactttc agctacaaaa cgtttccgtc ttgtagaagt tgtggaagag
     8461 gcagttatca tttaatcaac ctgaaaggag aaaattgaca tgattcaaac agaaactcgt
     8521 ttgaaagttg ctgacaacag tggcgcacgt gaaatcttga caatcaaagt tcttggtggt
     8581 tcaggacgta aattcgcgaa catcggcgac atcatcgttg cttcagtaaa acaagctact
     8641 cctggtggtg cggttaaaaa aggtgacgtt gttaaagccg ttatcgttcg tactaagaca
     8701 ggtgctcgtc gtgctgatgg ttcatacatc aaattcgatg agaatgctgc agttatcatc
     8761 cgtgaagaca aaaaccctcg cggaactcgt atctttggcc cagtggcacg cgaattgcgt
     8821 gatggcggtt tcatgaaaat cgtttcattg gcaccagaag tactttaatc aaatagtttt
     8881 aggaaatttg ttacaaacta acgaagtctg tgacgggttt agtaaactag aaaacaaact
     8941 aagtcccctg gttaaatcac taaccagggt gcccattagg gcgtaagaaa ttataggaga
     9001 aatcaaatgt ttgtaaaaaa aggcgataaa gttcgcgtaa tcgctggtaa agacaaaggc
     9061 gttgaagcag ttgtcgtaac agcacttcca aaagtaaaca aagttattgt tgaaggtgtt
     9121 aacatcgtta agaaacacca aaaatcaaac agcgaaaacc ctcaaggcgc tatcgttgaa
     9181 aaagaagctc caatccatgt gtcaaacgtt caagttcttg acaaaaatgg tgttgcagga
     9241 cgcgttggtt acaagtttgt agacggcaaa aaagttcgct acaacaaaaa atcaggcgaa
     9301 gtgcttgatt aatcacgaag gaaaggagaa gtataatggc aaatcgttta aaagaaaaat
     9361 atcttaatga agtagttcct gctttgactg aacaatttaa ctattcttca gttatggctg
     9421 tgccaaaagt tgataagatc gttttgaaca tgggtgttgg tgacgctgtt tctaacgcta
     9481 aaaaccttga gaaagctgct caagaattgg ctttgatctc aggtcaaaaa ccacttatca
     9541 ctaaagctaa gaaatcaatc gccggcttcc gtcttcgtga gggtgttgcg atcggtgcga
     9601 aagtaactct tcgtggcgaa cgtatgtatg aattcttgga caaattggtt acagtttcac
     9661 ttccacgtgt acgtgacttc cacggtgtac caactaagtc atttgacgga cgtggtaact
     9721 acacacttgg tgtgaaagag caattgatct tcccagaaat caacttcgac gatgttgata
     9781 aaactcgcgg tatggatatc gttatcgtta caactgctaa cactgacgaa gaatcacgtg
     9841 cattgcttac tggccttggt atgccgtttg caaaataaga gggagagaat aaatggctaa
     9901 aaaatcaatg atcgctaaga acaaacgccc agctaagttc tctacacaag cttacacacg
     9961 ctgtgaaaaa tgtggacgtc cacactcagt ttaccgcaaa ttcaaattgt gccgtgtatg
    10021 cttccgcgac ttggcttacc ttggacaaat tcctggcgta acaaaagctt cttggtaaga
    10081 taagatgtga gagcgtttag caaccaacgc aaagatagga gattttacga cgaagtttac
    10141 ttctaggaaa atctatcttc tttgctaagc ttgtagctcg aactcaatta aaacatgata
    10201 ctaagggcgt gacggacaaa gtgaaaatag gaactctagc gaagaacgct tgcgttctag
    10261 atagagttat ctttttcaca caggccgtag cccgagttca aatgttagga tgcaatagca
    10321 tcatactagc aaattcaaac tttgcattgc ctatcaggca cacattaact agcaagtgat
    10381 ctaatcaaac tgctagtaag aggagaaaca acaaatggtt atgactgacc caattgcaga
    10441 ttttttgaca cgtattcgta acgctaacca agcaaaacac gaagtgcttg aagtacctgc
    10501 atcaaacatc aaaaaaggta ttgctacaat ccttaaaaac gaaggttttg taaaaaacgt
    10561 tgaattcatc gaagatgaca aacaaggcat catccgtgta ttcttgaaat acggaccaaa
    10621 cggtgaaaaa gttatcacaa atttgaaacg cgtttcaaaa ccaggtcttc gtgtttactc
    10681 aaaacgtgaa gatattccta aagttcttaa cggacttggt atcgcaatca tctcaacatc
    10741 agaaggtctt ttgactgaca aacaagctcg tcaaaagaac gttggtggtg aggttatcgc
    10801 atacgtttgg taatctttta gcttccaatt tcgtcatgtg cctgtgttag agcgtcttga
    10861 catactcaag tatggtctgc gtcgctctgc cttgtcacat ttagaaattg aaacctaaaa
    10921 gcatgataca aatgcgagag gaccagttct tcgtgcgtgt tcaaatctga cttactgatt
    10981 atttggtatc atgcaaccaa actagaacaa gattcactaa ttgaacacgc ctacaactct
    11041 ttgaaaaaag tgaaaagtgt ttcagaaatc cttaccttgt tcgtcgtaaa cgtctgaact
    11101 ttctctggcc ttcggtcagg aaagtcctag tcgttctgac gagggtgcgt ctgcgaaatc
    11161 aaagacttcg gacttaccgc ttatttttct tcgagttgct taacggcttt gtatcttgtt
    11221 caccccgtga aaactagtcg cttgacggct tgataattta acaggagaat taaaaaatat
    11281 gtcacgtatt ggtaataaag taattacatt gcctgctggt gttgagcttg ctcaaaacaa
    11341 cggcgtggta actgtaaaag gacctaaagg ggaattgact cgtgaattcc caactgctat
    11401 tgaaatccgt gtggaaggtg cagaagtaac tcttcaccgt ccaaacgatt caaaagaaat
    11461 gaagactatt cacggtacta gccgtgctaa cctcaacaac atggttgttg gtgtttctga
    11521 aggcttcaaa aaagaacttg aaatgcgtgg tgtcggttac cgtgctcaat tggctggtaa
    11581 caaattgaca cttgctgttg gtaaatcaca tccagatgaa gtggttgcac cagaaggtat
    11641 cacatttgaa gttccaacac caacacaaat tgtcgtgtct ggtatcaaca aagaagttgt
    11701 tggtcaaaca gcagcttaca tccgtagcct tcgcgctcct gagccataca aagggaaagg
    11761 tatccgctac gttggtgaat tcgttcgccg taaagaaggt aaaacaggta aataatagct
    11821 tgctgaggtg gctggaccac ctggctgact atttctcaaa ttgtttcgta agaaacagaa
    11881 tcatacatta agaggtgaat attgtgattt caaaaccaga taaaaacaaa atccgccaaa
    11941 aacgccaccg tcgcgttcgc ggtaaaatct ctggaactgc tgctcgccca cgtttgaaca
    12001 ttttccgttc taatacaggc atctacgctc aagtgattga tgacgtagcg ggtgtaacgc
    12061 tcgcaagcgc ttctactctt gataaagaag tttcaaaagg tactaagaca gaacaagctg
    12121 ttgttgtagg taaactcgtt gctgaacgcg cggtagctaa aggtatttct gaagtggtct
    12181 ttgaccgcgg tggatatctc tatcacggac gtgtgaaagc tttggctgaa tcagctcgtg
    12241 aaaacggatt gaaattctaa tagggaggac actaagaaat ggcattcaaa gataacgcag
    12301 ttgaaattga agaacgcgta gtagccatca accgtgttac aaaagttgtt aaaggtggac
    12361 gtcgtcttcg ttttgcagct cttgtggttg ttggtgaccg taacggtcgc gtaggtttcg
    12421 gtactggtaa agctcaagaa gtaccagaag ctatccgtaa agcagttgaa tctgctaaga
    12481 aaaacatgat tgaagtacca atggttggta caacaatccc tcacgaagtt cgctcagaat
    12541 ttggcggcgc tcgtgtattg ttgaaacctg cttcagaagg ttctggggtt gctgccggtg
    12601 gtgcaactcg tgccgtaatc gaattggcag gtatcgcaga tgtgacttct aagtcacttg
    12661 gttcaaacac accaatcaac atcgttcgcg caacagttga aggtttgaaa caattgaaac
    12721 gtgctgaaga agtggctgca cttcgtggca tctcagtttc tgatttagca taagaaagga
    12781 gatactcatg gctcaaatta aaatcacttt gactaagtct ccaatcggtc gcaaaccaga
    12841 acaacgtaaa acagttgttg cacttggact tggtaaattg aactcttcag ttgttaagga
    12901 agataaccca gctatccttg gtatggtgaa cgctatctct cacttggtaa ctgtagaaga
    12961 agttaaataa tctaacaaat agactaagtc gcatagagaa atctttgcga cttctagtcc
    13021 attttacata tttacataca gcgagtttgt ggaggaagac tcttgtactt cacaggcgct
    13081 agcatataaa agaggagaaa taataatgaa acttcatgaa ttacaacctg ctacaggttc
    13141 tcgtaaagtc cgcaaccgtg taggtcgtgg tacatcatca ggtaacggta aaacatctgg
    13201 ccgtggtcaa aaaggtcaaa aagctcgtag cggtggcggt gtccgcccag gttttgaagg
    13261 tggacaaact ccattgttcc gtcgtcttcc aaaacgtgga tttacaaata tcaacgctaa
    13321 agagtacgca atcgttaacc ttgatcaatt gaacgctttt gaagatggtg cagaagtaac
    13381 accagttgtg cttatcgaag ctggaatcgt taaagctgaa aaatcaggaa ttaaaattct
    13441 tggtaacggt gaattgacga agaaattgac agttaaagct gctaaattct ctaaatcagc
    13501 tgaagaagca atcacttcta aaggtggctc agtagaagtc atctaagagg tggcagccta
    13561 tgttttttaa acttttaaaa gatgccttaa aggtaaaatt ggtacgtagt aaaattctat
    13621 ttactatctt tatccttttt gtcttccgcg taggaaccca cattacagta ccaggagtaa
    13681 acgcaaagag tcttgaggcc ttgtcaaacc ttccgttctt gaacatgttg agtttggttt
    13741 caggaaatgc tatgcgtaat ttctcagttt tcgcactagg tgttagtcct tatattacag
    13801 cttccatcat tgttcaactt ttacaaatgg atattttacc taaatttgtt gaatggggta
    13861 agcaaggtga agttggtcgt cgtaaactaa atcaagcaac acgctacatt tctttggtac
    13921 tggcatttgt tcaatcgatt ggtattacag caggctttaa tgctttgtcc ggtgcaaaat
    13981 tgaccaatat gccattaaat tggcaaacat atttgttgat tggagcgatt ttgacaacag
    14041 gttcgattat tgtaacctgg ctgggggaac agatttctga aaagggctat ggtaatggta
    14101 catcaatgat catctttgca ggaattattt catcgttacc aggaactttt cacgagattt
    14161 acattgatcg ctttgttaat attgaatcaa gtcgtttggg ggaatcagca atctttgttg
    14221 ctgcactcgt cgtattaata ttctttgttg tgtattttac aacttttgta caacaagcag
    14281 aatataaatt accaattcaa tatacaaaac gtgcacaagg agcaccttct agctcatatt
    14341 tacccctgaa attgaatcca gcaggagtta ttcccgtaat ctttgcaggc tcaatcactg
    14401 cagttccaac ttctttgatt caatatttcg caagtcaaaa taagagtgcc gggtggttat
    14461 tgacggttca ggaatacttt gattattcaa ctgctaaagg tatgattgta tatgcaggtt
    14521 taattattgc ctttacattc ttctacacct ttgttcaagt aaatcctgag aagactgcag
    14581 aaagccttca gaaaagtgca gcctatatcc atggagttcg tcctggtaat ggcactgaac
    14641 agtttttgtc aaaattattg acaagattgg cagtaatcgg tgcactcttc ttgagttttg
    14701 tagctttgct gcctatcctt gcgcaaaatc tctttgggct ttcttcaagc attgcgttcc
    14761 ttggtacaag tttgattatc gtaatctcta caagtatcga aggcatcaag caattagaag
    14821 gctaccttct taagagaaaa tatgtaggtt tcttagaaat tacagaatag aatataggtt
    14881 gacctagtca accttctatt ttgtttttag ataagtttgt caataatggc aaatttatgt
    14941 gaaaacaaaa taaggagttt gtcatgaatc ttttaattat gggtttacca ggtgctggta
    15001 aagggacaca agcggccaag attgttgaga aattcaatgt tgctcatatc tcaacaggag
    15061 atatgttccg tgcagcaatg gccaatcaga ctgaaatggg tattcttgcc aagtcgtaca
    15121 ttgataaggg tgacctcgtt cccgatgaag ttactaatgg cattgtcaaa gaacgtttgg
    15181 ttcaggatga catcaaggaa aaaggctttt tgcttgatgg ctatcctcgt acgattgaac
    15241 aagcccatgc cttggatgaa aatttggctg acttaggaat tgagttgcaa ggtgttatca
    15301 atattgagat tgatccttca aaattggtag agcgtctcag cggtcgtatt attcataaag
    15361 aaactggaga gactttccac aaagtattca atccacctgt tggagactac aaagaggaag
    15421 acttctatca acgtgaagat gacaagccag aatctgtcaa acgtcgttta gaggtcaata
    15481 tcgcacaagg acagccaatc attgatcatt atcgtgcaaa agggctggtc catgatattg
    15541 aaggtgacca agacattgac cttgttttcc aagcaattga tacagtacta tcaaaattgc
    15601 aataaactaa tagatttggc ttgcattttt tatacaaaga tgataaaata gtctagtctg
    15661 acttataatt gttacctctg tgttcagagg acatcaaatc gatatttaga gaggggttac
    15721 ttttgcatgg caaaagaaga tgtgattgaa attgaaggca aagtagtcga tacaatgcca
    15781 aatgctatgt ttactgttga gttggagaat ggacaccaag tccttgcaac tgtttcaggt
    15841 aaaatccgta aaaactacat tcgtattttg gtcggtgacc gcgtaactgt tgagcttagt
    15901 ccatacgact tgacacgtgg acgtatcaca taccgcttta aatagtcgaa atacttggag
    15961 ggattaaaca tgaaagtaag accatcggtc aaaccaattt gcgaatactg caaagttatt
    16021 cgtcgtaatg gtcgtgttat ggtgatttgc ccagcaaacc ctaaacacaa gcaacgtcaa
    16081 ggttaagaaa tagaaaggag aaaacatggc tcgtattgct ggagttgaca ttccaaatga
    16141 caaacgtgta gttatttcat taacttatgt ttatggtatc ggtcttgcaa catctaaaaa
    16201 aattcttgca gctgcaggta tttcagaaga tgtacgcgtg aaagatttga catcagatca
    16261 agaagatgct attcgtcgtg aagttgatgc aatcaaagtt gaaggtgacc tccgtcgtga
    16321 agttaacttg aacatcaaac gtttgatgga aatcggttca taccgtggta tccgtcaccg
    16381 tcgtggactt cctgtccgtg gacaaaacac taaaaacaat gcccgcactc gtaaaggtaa
    16441 agctgttgcg atcgcaggta agaaaaaata aaataggagg tagaaaaatt ggctaaacca
    16501 acacgtaaac gtcgtgtgaa aaagaatatc gaatctggta ttgcacatat tcacgcaaca
    16561 tttaataaca ctattgttat gattactgat gtgcatggta acgctattgc ttggtcatca
    16621 gctggtgctc ttggtttcaa aggttctcgt aaatctacac cattcgcggc tcaaatggct
    16681 tcagaagctg ctgctaaatc tgcacaagaa cacggtctta aaacagttga agttaccgtt
    16741 aaaggcccag gttcaggtcg tgagtctgct atccgcgctc ttgctgccgc tggtcttgaa
    16801 gtaacagcaa ttcgtgatgt gactcctgta ccacacaatg gtgctcgtcc tccaaaacgt
    16861 cgccgtgtat aatcatacat tccatacaca gcttttcgtt taagagggag taagaaatga
    16921 ttgagtttga aaaaccaaca ataacaaaaa ttgatgaaaa taaagattac ggcagatttg
    16981 taatcgaacc attagaacgt ggttacggta caactcttgg taactctctt cgtcgtgtac
    17041 ttcttgcctc acttccaggt gctgcagtaa catcgattaa aattgatggt gtactccacg
    17101 aattcgacac agttccaggt gttcgtgaag atgttatgca aattattctt aacatcaaag
    17161 gcattgctgt aaaatcttat gtcgaagacg aaaagaaaat tgaacttgat gtagtaggtc
    17221 cagctgaagt aacagcagga gacattctta cagatagtga cattgaaatt gtaaaccctg
    17281 accattatct ctttaccatt gctgatggtg ccacttttaa agctgttttg actgtcaatt
    17341 caggtcgtgg ttatgtacca gctgaggata ataagaaaga tgatgcacca gtgggaacac
    17401 ttgctgtaga ttctatctat acgccagtga agaaagtcaa ttatcaagtt gaaccagctc
    17461 gtgttggtag caacgatggt tttgacaaat taacacttga aatcaacaca aatggcacca
    17521 ttattccaga agatgcttta ggtctttctg cacgtatttt gatggagcac ttaggtctct
    17581 tcactgactt gactgaagtt gcaaaatctg cagaagtgat gaaagaagct gaagtggctt
    17641 cagatgatcg tatgcttgat cgtacgattg aagaattgga tctatctgtt cgctcatata
    17701 actgtctgaa acgtgcaggc attaacactg tattcgactt gacagagaaa actgagccag
    17761 aaatgatgaa agtgcgcaat cttggtcgca agagtcttga agaagttaaa gttaaattgg
    17821 ctgatcttgg tctaggattg aaaaaagata aataatatag gaggaaatca tggcataccg
    17881 taaactagga cgcactagct cacaacgtaa agcaatgttg cgcgatttga caactgacct
    17941 tttgatcaac gaatcaatcg ttacaactga agctcgtgct aaagaaatcc gtaaaacagt
    18001 tgaaaaaatg atcacacttg gtaaacgtgg tgatttgcac gcacgtcgtc aagcagcagc
    18061 atttgttcgt aacgaaattg catctgaaaa ctatgatgaa gcaactgata agtacacttc
    18121 tgctacagca cttcaaaaat tgttctctga aattgcacct cgttatgcag aacgtaatgg
    18181 tggatatact cgtatcctca aaactgaacc acgtcgtggt gatgctgcac caatggcaat
    18241 tatcgaactt gtataagatc atcaattttg ttgagtgtta tgatgatgga atcctattct
    18301 gattcttagt ctagctctgg tctaccgctg agcttgtctc agcggtaaca ctcatcatgt
    18361 tgattggacg cttgtttacg aaattactct aagatagaat aatttcgtaa gcaggcgttt
    18421 ttattttact caaaaatttt gatatactgg aggcatacga agaaaatata caatctccga
    18481 ttagtatgcc tctcagtttt tcgccaaatt tcataaaaaa a
//
LOCUS       DBNFCO010000043        17013 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.043, whole genome shotgun sequence.
ACCESSION   DBNFCO010000043 DBNFCO010000000
VERSION     DBNFCO010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 17013)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17013)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17013
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.043"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(230..940)
                     /locus_tag="AC1PIV_001226"
     CDS             complement(230..940)
                     /locus_tag="AC1PIV_001226"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HIP6612251.1"
                     /translation="MKALIFDVDDTLYDQIQPFERALERHIEVAREQIEPLYLSFRRY
                     ADEVFEATAIGKMSLKDSHIYRMKHALADFGYQVSDATALAIQIDYDYFQGQIELSPV
                     FPEIFSWCQVQGIAMGIITNGPYRHQLRKIRTMGLVNWFELEHVLISGQVGITKPNPA
                     IFQLMEERLGMSGEDICYLGDSFENDIIGAKTAGWQAVWFNHRKRSEPESSFQADYMI
                     DEWFNLDSLIKNIIKPIG"
     gene            complement(994..2733)
                     /locus_tag="AC1PIV_001227"
     CDS             complement(994..2733)
                     /locus_tag="AC1PIV_001227"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIP6612252.1"
                     /translation="MTILGFLLKQIRRVKCLFIVAVGFYLLASTMVRLAPLLIQQAID
                     GPITDLSKGLPFDEAVFLNQSVQYMGMIILGAIGFYLSMRLLMHCANRIAENLRNQAY
                     DVMQRLPISYFDDKPAGKIATRIVNDTETLRTQFYGTLVNAFNNIVRLLFTYGVLFYM
                     NRSLGWLMLLLIPLYIGIQFAYKKMTDKPMKDFYDARSDVNTQVNETMNGASLIQLFG
                     QEERIMKEFEVTADKMRRADNKIIWAQSLATWNLSGFLQNLVIAAILTVVGYQFLAGQ
                     DGVTAGKLFVYVNYIEGVFIALGALVQQFPNMLRSFETGKRLMALLEEELEDDCDRIL
                     EVEQGQVVFEHVNFSYEENRPVLKDITIRAEKGETVALVGHTGSGKSSIMNLLYRFYD
                     PQEGCVLIDGKNIRDYSRESLRSHMGIVLQDPYLFTGTIASNVSMNEEEADRTRIMQA
                     LEKVGAGPMLSRLEKGIDEPVVEKGAAFSSGERQLIAFARTLYSDPKILILDEATSHI
                     DTETEEIIQHAMEVVKEGRTTFIIAHRLSTIQNADQILVLDQGRIIEHGKHEELVARG
                     GVYAQMHEIQAKV"
     gene            complement(2733..4460)
                     /locus_tag="AC1PIV_001228"
     CDS             complement(2733..4460)
                     /locus_tag="AC1PIV_001228"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIP6612253.1"
                     /translation="MFRLIFDYIKRHKWLYLLVAVTLIIYDATLLLPTQIIQRMVDIL
                     TKNELTQAILVQEMTLLLLVTVLNYATAFIWHLKLFQASVNFKFDMQQRAFKKLVTMR
                     TPFYEKFRSGDVMTRFSTDVDGLMEMVGYGLMIVVYAGGMLAFIIPTMFFIDWKISLV
                     ALLPMLFMTLCIFFIGRKQDKAIDANREAVAQLNNEVLEVIEGIRVTRAYSKKANQKA
                     QFQARTKQLAQGGDRITSLQSLYNPLATVCLGLSTIFVLLMGAQAVKAGQLTLGQVIA
                     LQLYVGSLLEPFWTLADFILVYQTGKTSFEKLQELIETGDDLEADGSKEIAELSSISF
                     KNYSFSYPQAERASLQDINWTLKAGQTVGIVGKTGSGKTTLVRQFLRQYPIGQGNFFI
                     NHQSILDFKRSSIEEKIGYVPQEHILFSRSVGENIALGKVASSSEEIEQAIATAAFSQ
                     DLKRMSDGLDTMIGERGVSISGGQKQRISIARAFLREPDLLILDDSLSAVDARTERQI
                     IQNIQKERAGKTNVIVTHRLSAVNHADWVLVLDEGRIVEEGRPADLLAQRGWYYEQYQ
                     RQQSQEGGE"
     gene            complement(4930..5002)
                     /locus_tag="AC1PIV_001229"
     tRNA            complement(4930..5002)
                     /locus_tag="AC1PIV_001229"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(4967..4969),aa:Thr,seq:ggt)
     gene            5159..5629
                     /locus_tag="AC1PIV_001230"
     CDS             5159..5629
                     /locus_tag="AC1PIV_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046914 - transition metal ion binding
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FeoA family protein"
                     /protein_id="HIP6612254.1"
                     /translation="MKLQNLQVGQSYLVKDCLTQDDIRKHLAHLGLKVGEEIRIISKT
                     KTNAIFQVKASRLALDREIIESLVLTEKSATEIINLSEAPIGSSAKVMDIYATGALRR
                     RLMDMGLTKNTQLFLKKVAPLGDPIETTLRGYELTLRKSEAQMIGVQITSEVRK"
     gene            5626..7770
                     /gene="feoB"
                     /locus_tag="AC1PIV_001231"
     CDS             5626..7770
                     /gene="feoB"
                     /locus_tag="AC1PIV_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HIP6612255.1"
                     /translation="MTKHIALAGNPNSGKTTLFNLLTGTNQRVGNWPGVTVERKSGTI
                     KKRKHLLIQDLPGIYSLSPYTPEERVARDYLIADQPAAILNVLDATNLERNLYLTLQL
                     LEMGLPIVIALNMTDALKSQGRSINSDQLSYQLGVPVQPISALKKLGISQLLHEVEKI
                     TNQQAEPIYPQYDKQFEAGLAQVIDLLSDSIPNRQKRFYAIKLLEQDQVILDQLQLNA
                     QDMLDLTEIIAILEKIYADDMEAIIVNQRYQFIEKITELVTKDSDKAFNLSDNIDRLV
                     TNRFLALPIFAAVMWLTYFLSIQTVGTMGTDWVNDVLFGELVPGLIQANLDRFEIAGW
                     LQSLVLDGIIAGCGAILGFVPQIFVLFVCLGILEDIGYMSRVAFVMDRIFRRFGLSGK
                     SFIPMLISTGCGVPGVMASRTIENEQDRKITIMTATFMPCSAKLPIISLVAGAFFPDN
                     PWIAPSAYFVGMAAIVLSGMALKKTKQLGGVASPFIMELPSYHLPKLSTVLRYAFDKA
                     LSFIKRAGTIIFVTNIIIWFSSSYNWSLQMVETDESILASIGHSFSLLFAPLGFGNWR
                     ATVAAITGLLAKETVIATFGILYKLGETTEENPELWGLLQQDYTALSAYSFLVFNLLC
                     APCFAAIGAIHREMGEAKWTWIAIGFQTGLAYASSLVIYQIGLVLIHGQLPTVWTFIA
                     IFLIITAIYSLVKKPTNTLPIVTLKTLEKGEY"
     gene            7770..7922
                     /locus_tag="AC1PIV_001232"
     CDS             7770..7922
                     /locus_tag="AC1PIV_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HIP6612256.1"
                     /translation="MPTLILFLIIVILFSLAIRSLIKGKGSCGDCSCDCTIKQEMNES
                     SHHRHP"
     gene            complement(7975..8904)
                     /gene="ftsX"
                     /locus_tag="AC1PIV_001233"
     CDS             complement(7975..8904)
                     /gene="ftsX"
                     /locus_tag="AC1PIV_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease-like cell division protein FtsX"
                     /protein_id="HIP6612257.1"
                     /translation="MSNRFFRHFIESLKSLKRNGWMTIAAISSVAITLTLVGLFASVI
                     LNTAKLASDLEQNVRINVYLRANSTDQAETIVNEAGETVANPDYKKVYNQITALENVQ
                     SVTYSSKDEQLQKLTATLGDTWNLFQGDANPLYDAYIIDTTEPQYVKTVAAEIAKIDG
                     VTEVRDGEVETERIFKLANLVRTWGLAATGLLLFTAVFLISNTIRITIISRSREIQIM
                     RLVGAKNSYIRGPFLWEGAWVGLLGAILPSALVYSFYKMIYTSVNASLASQDLSLISM
                     DVFVPGMIGALFVIGIIIGSLGSVISMNRYLKI"
     gene            complement(8897..9589)
                     /gene="ftsE"
                     /locus_tag="AC1PIV_001234"
     CDS             complement(8897..9589)
                     /gene="ftsE"
                     /locus_tag="AC1PIV_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HIP6612258.1"
                     /translation="MGIIEMKDVSKKYGNGTTALRGVSVNVEAGEFAYIVGPSGAGKS
                     TFIKLLYREEKLDKGSLKVGKFDLAKIKKRDVPLLRRSVGVVFQDYKLLPKKTVFENI
                     AYAMEVIGEKPRNIKKRVMEVLDLVGLKHKIRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPENSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIEDGRVV
                     RDEAEGEYGYDE"
     gene            complement(9732..10827)
                     /gene="prfB"
                     /locus_tag="AC1PIV_001235"
     CDS             complement(join(9732..10754,10756..10827))
                     /gene="prfB"
                     /locus_tag="AC1PIV_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775232.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HIP6612259.1"
                     /translation="MDTAEIRQKIEELGKKLTSFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNLAAQKTSQELNELKNTYGNFHQMLDLYDESEILLDFLAEDESVRDELVEKLVE
                     LDKTMTAYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGEMLLRMYQRYGNAKGFIV
                     ETLDYQAGDEAGIKSVTLSFTGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEIEIRDDEVKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVTQSTVDRT
                     QYGNRDRAMKLLQAKLYQLEQEKKAAEVDSLKGDKKEITWGSQIRSYVFTPYTMVKDH
                     RTGYEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            complement(10862..11989)
                     /gene="queG"
                     /locus_tag="AC1PIV_001236"
     CDS             complement(10862..11989)
                     /gene="queG"
                     /locus_tag="AC1PIV_001236"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0052693 - epoxyqueuosine reductase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HIP6612260.1"
                     /translation="MNIKEEIIKLSQEIGISKIGFTTADDFAYLEKSLRASQEEGRSS
                     GFEHKNIEERIRPKLSLESAKTIISIAVAYPRHLPVKPQKTQYKRGKITPSSWGLDYH
                     YILQDKMERLARGIEKLTDGLEYKAMVDTGALVDTAVARRAGIGFIGKNGLVISKEFG
                     SYMFLGELVTNLDIEPDQPVDYDCGDCNRCVAACPTSCLLGDTTMNARRCLSFQTQDK
                     GMMDLEFRKKIKTVIYGCDICQICCPYNKGISSPPVVEIDPDLAEPELIPFLDLSNGQ
                     FKEKFGMIAGSWRGKNILQRNAIIALANSNDRSAIPKLLEIIDKKQNPVHMATAIWAL
                     GQLVKQPNDEMVSFIAGISSDNDDVIAEQAAFLNMVKDLQM"
     gene            complement(12030..12518)
                     /locus_tag="AC1PIV_001237"
     CDS             complement(12030..12518)
                     /locus_tag="AC1PIV_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HIP6612261.1"
                     /translation="MQTKKMSMFLFFAYLLLLTWMIIFKMDLSIVYGRYGYASINLIP
                     FAGTAVYDGVLDFPEILFNIVSFIPFGIYMEMLFRKASWVTNLCLIMLVSLCFEVLQY
                     LLLLGVADITDLLANGLGGAIGINIMYVLTSIWREKAYVRMNIFCFVLTFFVILITYL
                     AM"
     gene            complement(12688..13104)
                     /locus_tag="AC1PIV_001238"
     CDS             complement(12688..13104)
                     /locus_tag="AC1PIV_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001540 - amyloid-beta binding [Evidence
                     IEA];
                     GO_function: GO:0004930 - G protein-coupled receptor
                     activity [Evidence IEA];
                     GO_process: GO:0097190 - apoptotic signaling pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TM2 domain-containing protein"
                     /protein_id="HIP6612262.1"
                     /translation="MNYLQNYILSKSSYLPSDKLFILQKELEDLDDEALNVLMMVEMR
                     QPLVALILAIFFGEFGVDRFYVGNKELGFAKLIAFAVSFVTLFILIGFLLFLGLYLWK
                     FIDCFLIMRACKEANFERLMLQIHQYKAFQHSNQTF"
     gene            13238..13438
                     /locus_tag="AC1PIV_001239"
     CDS             13238..13438
                     /locus_tag="AC1PIV_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612263.1"
                     /translation="MRVIIHYPKPIKQLSSQKLPLLVDGKIAGTVTQGKILSLPITQP
                     SVTLSIRGDKKSSIQVKEGDRV"
     gene            13540..13731
                     /locus_tag="AC1PIV_001240"
     CDS             13540..13731
                     /locus_tag="AC1PIV_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612264.1"
                     /translation="MTMESSKYFTPYYFSLAIVPIALLFNLPTLVKTFLLILALAITL
                     LGQAIFPKYIISTEKSSDH"
     gene            complement(13847..16534)
                     /locus_tag="AC1PIV_001241"
     CDS             complement(13847..16534)
                     /locus_tag="AC1PIV_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HIP6612265.1"
                     /translation="MSKEQKRDLFYTQSEEQVLSSMGSSLDGLSSDEASKRLADYGRN
                     ELDEGEKRTLLAKFLDQFKDLMIIILIAAAILTVITEGSHGLTDAIIILAVVILNAAF
                     GVYQEGQAEAAIEALKNMSSPVARALRDNHVVEVDSKDLVPGDIVLLEAGDVVPADMR
                     LLEANSLKIEEAALTGESVPVDKDLSAVLAEDAPIGDRVNMAYQNSNVTYGRGLGVVT
                     NTGMYTEVGHIAGMLANADETDTPLKQNLHQLSKVLTYAVLVIAAVTMAVSVFVRGEG
                     ILPALMTSVALAVAAIPEGLPAIVTVVLSLGTQVLAKRNSIIRKLPAVETLGSTEIIA
                     SDKTGTLTMNQMTVEKVYTNGQLVDAKEALDASNTTLRVMNFANDTKVDPTGKLIGDP
                     TETALVQFGLDQNFDVREVLVSEPRVAELPFDSTRKLMSTVHQQAAGNFFVAVKGAPD
                     QLLKRVTQIEENGTIRPITDADKQAILATNKDLAKQALRVLMMAYKYVDAIPELESDV
                     VENDLVFSGLVGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGIIDP
                     NDTEDHVFTGAELNELTDEEFQKVFKQYSVYARVSPEHKVRIVKAWQNDGKVVAMTGD
                     GVNDAPSLKTADIGIGMGITGTEVSKGASDMVLADDNFATIIVAVEEGRKVFSNIQKT
                     IQYLLSANTAEVLCIFLATLFGWDVLEPVHLLWINLVTDTLPAIALGVEPAEPGVMQH
                     KPRGRNSSFFSGGVLSSIIYQGILQTALVLGVYGFALLYPEHAGDNHAIHADALTMAY
                     VTLGLIQLVHAFNVKSVYQSIFTVGPFKNKLFNWSIVAAFLLLMATVVIPGFNTFFKV
                     SILTPTQWMVTVIGSGLMVVVVEIVKFVQRKLGLDEKAI"
     gene            16859..>17013
                     /locus_tag="AC1PIV_001242"
     CDS             16859..>17013
                     /locus_tag="AC1PIV_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIP6612266.1"
                     /translation="MKNKHLTLSDRNDIQIGIEQLKPFSAIAAKLGKDPSTISKEVRR
                     NRVIKENS"
BASE COUNT         5242 a         3938 c         3044 g         4789 t
ORIGIN      
        1 gttggaaata agacatgcga agcaagtcac tttcgtggag tacggcaaag cgagttcaaa
       61 caatccagtg gagtgtttga agtaggaaat aagaaaacgg agtttcctct tgcgtcgaag
      121 taattaaaga taaactaaat gactatacct cctctttttg aacacaaaaa ctcccccgac
      181 tagcttctaa tcctattaaa aacttgttag gagagttatt ccattttatt tatccaatcg
      241 gctttatgat gtttttgata agggaatcca gattgaacca ttcgtcaatc atataatctg
      301 cctgaaagga actttctggc tctgaccgtt ttctgtgatt aaaccagacc gcttgccaac
      361 cagctgtttt tgccccgatg atgtcatttt caaacgaatc ccctagataa caaatatctt
      421 cgcctgacat ccccaaacgt tcttccatta gttgaaaaat agcaggattt ggctttgtga
      481 taccaacttg tccagaaata aggacatgtt ctagctcaaa ccaattaact aaccccatcg
      541 tgcgtatctt tctcaactga tgtctataag gtccattcgt aataatcccc attgcaattc
      601 cttgcacctg acaccacgaa aatatttctg gaaacactgg actgagctct atctgccctt
      661 gaaaataatc ataatctatt tgaatagcta aggctgttgc atcagacacc tgatacccaa
      721 aatctgccaa agcatgtttc atccgataaa tatgactgtc tttcaaactc atctttccaa
      781 ttgctgtcgc ttcaaatact tcatccgcat atctgcgaaa ggaaaggtag agtggttcaa
      841 tttgctccct tgctacttca atgtgtcttt ccaaagcacg ttcaaacggt tgaatctgat
      901 cataaagcgt atcatctaca tcaaaaatta aggctttcat gagtcaatta tagcaaaaaa
      961 ttccagcaaa agcttggaat ttttaactgc ttattacacc tttgcttgaa tctcatgcat
     1021 ttgagcatat actccaccac gtgcaaccaa ttcttcatgc ttcccatgtt caataattcg
     1081 accttgatct aagacaagaa tctggtctgc attttgaatg gtagaaagtc ggtgagcaat
     1141 aataaaggtt gtccgacctt ctttcaccac ttccatggca tgttggataa tttcttccgt
     1201 ctccgtatca atatgagaag ttgcttcatc caatatcaga attttaggat cagagtagag
     1261 tgtccgcgca aaggcaatca attgacgttc cccacttgaa aaggccgccc ccttctcaac
     1321 aaccggttca tcaatccctt tctctaagcg agatagcata ggccctgcac caactttttc
     1381 tagcgcctgc atgattcttg ttctatctgc ttcctcttca ttcatggaaa cattgctggc
     1441 aatcgtccct gtaaagagat agggatcttg caaaacaatc cccatgtgac tgcgcaggct
     1501 ttcacgagaa taatcacgga tgtttttccc atcaatcagt acacatccct cctgtggatc
     1561 atagaaacga tagaggagat tcataataga agacttacca gacccagtat gcccaaccag
     1621 agcaactgtt tctccttttt ctgctcgaat ggtaatatct ttcaaaactg gtctgttttc
     1681 ttcatagcta aagttcacgt gttcaaacac gacttgccct tgttcaactt ccaaaatacg
     1741 atcacagtcg tcctccagct cttcttctag aagggccatt agacgcttac ctgtttcaaa
     1801 cgagcgaagc atatttggga actgttgaac cagcgctccc aaagcaatga agactccttc
     1861 gatatagttg acataaacaa agagtttccc agctgtaact ccatcctgtc ccgcaagaaa
     1921 ttgatagccg actaccgtta aaatcgcagc aatgaccaaa ttttgcagaa aaccactcag
     1981 attccacgtg gcaagagact gggcccagat aatcttatta tctgcccgac gcatcttgtc
     2041 agcagtcact tcaaattctt tcatgatgcg ctcttcttgt ccaaaaagtt gaatcaaact
     2101 tgcaccattc atggtctcat tcacctgcgt attgacgtca ctccttgcat cataaaaatc
     2161 cttcatcggc ttgtctgtca ttttcttgta agcaaattga ataccgatat agagtggtat
     2221 caagagtaac atcagccaac caagactcct attcatataa aataggacac cgtatgtaaa
     2281 gagcaaacga acaatattgt taaaggcatt aactaaggtc ccataaaatt gtgtccgcag
     2341 agtttctgta tcattgacaa ttctagttgc aatttttcca gcgggcttat catcaaaata
     2401 agaaataggc aaccgttgca taacatcgta ggcttgatta cgtagatttt cagcaatacg
     2461 attggcgcaa tgcatgagta aacgcataga taagtagaag ccaatagctc ccagaataat
     2521 cattcccatg tattgaactg actggtttaa gaaaacagct tcatcaaaag gcaaaccctt
     2581 gctcaaatcc gtaatcggcc catcaatcgc ctgctgaatc agcagaggag ccaatcgaac
     2641 catggtcgaa gccaatagat agaagccgac agctactata aatagacact tgactcgacg
     2701 gatttgtttt aataaaaaac ctaaaatagt cattactctc ctccttcctg gctttgttgt
     2761 cgttggtatt gttcatagta ccaacctctt tgggcaagca aatcagctgg acgcccttcc
     2821 tcaacgatac gcccctcatc caagactagt acccagtctg catggttgac agcagataga
     2881 cgatgggtca cgatgacatt ggttttgcct gcacgttctt tttgaatatt ttggataatc
     2941 tggcgttctg tcctagcatc cactgccgac aaagaatcat ctagaattag caaatctggc
     3001 tctcgcagga aagcacgggc aatggaaatc cgttgtttct gaccaccaga aatagacaca
     3061 ccacgctcac caatcatggt atcaagacca tcactcatcc gttttaaatc ttgactaaaa
     3121 gctgctgtgg caatggcttg ttcaatctcc tcagagctac tagctacttt ccctagggca
     3181 atattttctc caacagacct tgaaaacaaa atgtgttctt gtggaacata gccaattttt
     3241 tcctctatac tagaacgttt aaagtctaaa atagattgat gattgatgaa aaaatttccc
     3301 tgaccaatcg gatactggcg taagaattgg cgaaccaagg tcgtttttcc cgaaccagtt
     3361 ttcccaacga tacctacagt ttgccctgct ttcagtgtcc aattgatgtc ctgtaggctg
     3421 gctctttccg cctgtggata actaaagcta taatttttga aggaaatact agacagctct
     3481 gcaatttcct tagaaccatc agcctccaaa tcatcacccg tctcaatcag ctcttgcagt
     3541 ttttcgaaag atgtcttacc agtctgataa acaaggatga aatctgctag tgtccaaaac
     3601 ggctctaaaa gcgaaccgac atacaattga agggcaatta cttgtcccaa ggtcagttgc
     3661 cctgctttca cggcttgtgc ccccatgaga agtacgaaaa tagtagacaa tcccaaacag
     3721 actgtggcta atggattata caatgattgc aaggaagtga tgcgatcccc accttgagcc
     3781 aattgcttgg tacgagcttg aaattgagcc ttttgatttg cttttttact ataagcccga
     3841 gtcactcgaa tgccttcgat gacctccaaa acttcattat tgagctgggc tacagcttct
     3901 ctattggcat caatcgcctt atcttgtttt ctcccgataa aaaatataca tagtgtcatg
     3961 aacagcatcg gtagtaaagc tactagcgaa attttccaat caataaagaa catcgtggga
     4021 atgataaaag ccaacatacc gcctgcatag acgacaatca taagaccgta acccaccatc
     4081 tccatcaggc catccacatc cgttgaaaaa cgagtcatga catctcctga gcggaatttt
     4141 tcataaaatg gagtccgcat ggtcactaat tttttaaagg cacgttgctg catatcaaac
     4201 ttgaaattga cagaggcctg aaataatttc agatgccaaa tgaaggctgt tgcatagttc
     4261 agcactgtta ccaataacaa taaggtcatc tcctgaacca atatggcctg tgttaattca
     4321 ttcttggtta gtatatcgac catccgctga atgatttgcg ttggtagcaa aagtgtggcg
     4381 tcataaataa tcaaggtcac agcaaccaat agatagagcc acttatgacg cttgatatag
     4441 tcaaaaatta atcgaaacat atatctcctt tacaaatcca taacctatca tttgccactt
     4501 tattcaataa gctacaattg atagacctta cttttctaag ctaagcgcac aaaaaagccc
     4561 agggaagcat ctcactccac ctaggcttgc gtaagtccac aaaaatagac cagctcttga
     4621 acatagtcga caatttttat cacaccatac ccacagtgct tgattgtctc aatgtttcaa
     4681 aatatagccc acgaaaaacg acaaaagttc atcaatgagc tttgttttcc tgcttagaaa
     4741 ggagtgtatg ataaaaaata gcttgctgaa tgacaagttg cttgttcatt tgttttactc
     4801 ctttcatatt tctaagccct attctaccat aataaacatt catgtcaagg gattttttga
     4861 caataagggc gaatttagga caaaaataag aaaaaacctt gtcaaacaag gcctttcgat
     4921 agtattcgat gctagttgcc gggattgaac cggcgacctc atccttacca tggatgcgct
     4981 ctaccgactg agctaaacca gcagtacttg actagtatat catatctcta aaaaaagtca
     5041 atggattttt tggaaatatt gagaaaaata aagagaaaat aagtcattcc taaaaattgt
     5101 ctgacacttt taaggaattg tgctatacta ttgttataaa aatcacaaag gaaacgatat
     5161 gaaactgcaa aaccttcaag ttggacaatc ttatttagtc aaagattgtc taacgcaaga
     5221 tgatattcgt aaacacttag cacacttggg tttaaaagtc ggagaagaga ttcgcatcat
     5281 ttcaaaaacc aagaccaatg caattttcca agtcaaggca agccgtctag ccctagacag
     5341 agaaattatt gaatctctgg ttttaacaga aaagtcagct acggaaataa tcaatctatc
     5401 cgaggcacct attggtagct cagctaaggt tatggacatc tatgcaacag gtgcactccg
     5461 tcgtcgcctc atggatatgg gacttacaaa gaacacgcag ctatttctca aaaaagtcgc
     5521 tcccctgggc gatccaatcg aaactacctt gagaggatac gagctgacac tacgcaaatc
     5581 cgaagcgcaa atgattggtg ttcaaatcac aagcgaggtg aggaaatgac aaaacacatc
     5641 gcccttgcag gaaatccaaa tagcggaaaa acaactcttt tcaacctcct aacaggaacc
     5701 aaccaacgtg tcggtaactg gcctggagtc accgttgaaa gaaaatctgg aacgatcaaa
     5761 aagcgaaaac atttactaat tcaagattta ccaggtatct actcgctgtc tccctacaca
     5821 ccagaagaac gggttgccag agattatttg atagcggacc aaccagctgc tatcctcaac
     5881 gtccttgatg caacaaactt ggaacggaat ctctatctga ccttgcagtt attagaaatg
     5941 ggccttccta ttgttatcgc cctcaatatg acagacgccc tgaaaagtca aggtcgctca
     6001 ataaacagcg accagctctc ctatcaactg ggagttcctg tacagcctat cagtgcacta
     6061 aaaaagctag gtatatccca gctcctccat gaagtagaaa aaattaccaa tcagcaagcc
     6121 gagccaatct atcctcagta tgacaaacaa tttgaagccg gcctcgccca agttattgac
     6181 ctattatcgg attccatccc aaatcgtcaa aaacgcttct acgccattaa gctactcgaa
     6241 caagaccaag tcattctaga ccaattgcaa ctaaatgcac aagacatgct tgatttgacc
     6301 gaaatcattg ccattttgga aaaaatttac gcagacgata tggaagccat tatcgtcaat
     6361 caacgctacc aatttatcga gaaaatcaca gaactggtca caaaagacag cgataaggct
     6421 tttaacctgt ctgataacat agaccgactt gttaccaatc gttttcttgc cctccctatc
     6481 tttgcggcag tcatgtggct gacctacttc ctgtctattc aaacggtagg tacaatgggg
     6541 actgactggg tgaatgatgt cctcttcgga gagcttgttc caggccttat tcaggcaaat
     6601 ctagatcgat ttgaaatcgc tggctggcta caatctctgg tccttgatgg cattattgca
     6661 ggatgcggag ccattctagg ttttgtacca caaattttcg tcctcttcgt ctgcttggga
     6721 atcttggaag acatcggcta tatgagccga gtcgcctttg tcatggatag gatttttaga
     6781 cgttttggtc tatcaggcaa atcctttatt cccatgttga tttccacagg ctgtggcgtt
     6841 cctggagtca tggcaagccg gactattgaa aatgaacagg accgaaaaat caccattatg
     6901 acagcaacct tcatgccctg ttctgccaaa cttcctatca tttcactggt agccggtgct
     6961 ttctttcctg acaatccttg gattgctcca agcgcctatt ttgtcggtat ggctgccatc
     7021 gtcctatccg gaatggcact aaaaaagacc aagcaacttg gtggagtcgc aagccccttt
     7081 atcatggaat taccatctta tcacttacca aaactcagta cggttctccg gtatgcattc
     7141 gataaggcac ttagttttat caaacgagct ggtaccatta tatttgtgac caacatcatt
     7201 atttggttca gcagttccta taattggtct ttacaaatgg tagaaacaga tgagagtatc
     7261 ttagcctcca ttggacacag tttttctctc ctctttgccc cacttggttt cggaaattgg
     7321 cgagcaactg ttgcagccat tacaggtctc ttagccaagg aaaccgtcat tgccaccttt
     7381 ggtatcctct ataaattagg agaaacaacc gaagaaaatc ccgaactatg ggggctttta
     7441 caacaagact atacagcgtt atcagcctac tccttcctag tcttcaatct cctctgtgcc
     7501 ccttgttttg cggctattgg tgccattcac cgtgaaatgg gagaagccaa gtggacatgg
     7561 attgctatcg gtttccaaac gggtttagcc tatgcaagta gtttggttat ctatcagatt
     7621 ggtcttgtac ttatccacgg acaattacca accgtctgga catttatcgc tatctttcta
     7681 attatcacag ccatctacag cctagtgaaa aaaccaacca acactcttcc aatcgtcacg
     7741 ctaaaaacat tagaaaaagg agaatattaa tgcccacact tatcctcttt ctcatcatcg
     7801 tcatcttatt ttctcttgcg attcgcagtc tcatcaaagg aaaaggatcc tgcggagatt
     7861 gttcctgcga ctgtactatt aagcaagaga tgaacgaatc ttctcaccat agacatccat
     7921 aacaaaaagg tctgcctcat tattgtgcag acctttttac atgtagcttg tctattaaat
     7981 ttttaagtag cggttcatgg aaatgactga tcccaaggaa ccaataataa taccaattac
     8041 aaaaagtgcg ccaatcattc ctggaacaaa gacatccata ctaatcagag acaaatcttg
     8101 actagcaaga ctagcattta ccgaagtata aatcatctta taaaaagaat agactaaagc
     8161 agaaggcaaa atagctccga ggagacctac ccaggcacct tcccagagga atggtccacg
     8221 gatataactg tttttagcac caaccagacg cataatctga atttcacggc tacgagaaat
     8281 aatggtaatt cgaatagtat tggaaatcaa gaaaacagca gtaaagagca ataagccagt
     8341 tgctgccaat ccccatgtac gaactagatt agctaattta aaaatacgtt ccgtttcaac
     8401 ttccccatcc cgtacctctg taacaccatc aattttagca atctctgctg caacagtttt
     8461 tacatattgc ggttcagtcg tatcaatgat ataagcatcg taaagtggat tggcatctcc
     8521 ttggaatagg ttccaagtat ctcccaaggt agctgttaat ttctgtaact gttcatcctt
     8581 acttgaataa gtgacagatt gtacattttc taaggctgta atctgattat acaccttttt
     8641 ataatctgga ttagctaccg tctctcctgc ttcgttcaca atcgtctcag cttgatcggt
     8701 tgaattcgct ctcaaataca cattgatgcg tacattctgt tccaaatccg aagcgagctt
     8761 tgctgtgttc aaaataactg aagcaaatag accaaccaag gtaagggtaa tggctacaga
     8821 tgaaatggct gcaatcgtca tccaaccatt tcgcttcaaa ctcttcaatg actcaataaa
     8881 gtgtctaaaa aatcgattac tcatcgtatc catattctcc ttccgcttca tcacgtacta
     8941 cacgaccatc ttcaatcgca ataacacgat gacgaagtgt atttacaatc tgactattgt
     9001 gtgtcgccat caaaatcgtt gtcccctgta agttaattcg ctccaataga ttcatgattt
     9061 cccaagagtt ttcagggtcc aagttaccag ttggttcatc agcaatcaat actttaggat
     9121 tatttacaat ggcacgggca atagcaatac gctgttgctc accacctgaa agttcatttg
     9181 ggaaagaacg aattttgtgt ttcaaaccaa ccaaatctaa aacttccatt acacgtttct
     9241 tgatattccg tggtttctca ccgataactt ccatcgcata agcaatattt tcaaagacag
     9301 tctttttagg taagagtttg tagtcttgga aaaccactcc tacactacga cgtagaagag
     9361 gaacatctct ctttttaatt tttgcaaggt caaacttacc aacctttaga ctccccttat
     9421 cgagcttttc ctcccgatac aagagtttga taaaggttga cttacctgca ccagaaggac
     9481 ctacaatgta ggcaaattct cccgcttcaa cattgactga tactccgcga agggcagtcg
     9541 ttccgtttcc atatttcttg gaaacgtctt tcatttctat tattcccata ggatttcctg
     9601 tcttagacag tcctttcttt agatttgaga acgttttttt caaaatacag tccgtattct
     9661 ctaaaaaaac ttccttgatg agcgaaaaac tatctcttat ttacaagcac ttcacttgta
     9721 aatacaggtt cttagctaat tcgccatttt aaataagcat ctataaagcc gtccaagtct
     9781 ccgtccataa ccttatcgac ttgagccacc tcataaccag tacggtggtc ttttaccatt
     9841 gtataaggtg taaagacata agaacgaatc tgacttcccc aagtgatctc tttcttgtca
     9901 cccttaagtg agtctacttc tgccgctttc ttctcctgct ccaattgata caatttagcc
     9961 tgcaagagtt tcattgcacg gtctcggttt ccatactgag tacggtcaac tgtggactga
    10021 gtcacaatcc ctgtcggaat gtgcgtcaat cgaacacccg ttgaaacctt attgacgttc
    10081 tgtccaccag cacctcctga ccggaaggta tccatcttca cttcatcatc tctgatttca
    10141 atttcaatgg tatcatccaa ctcaggcatt acctccacag atgtaaagga agtatgacga
    10201 cgcttagctg agtcaaaagg tgagatgcgc accaaacgat gaacacccat ttctgactta
    10261 agcaagccat aggcgtttgg accagtaaag cttagagtca cagacttaat acctgcctca
    10321 tcaccagctt gataatccaa tgtttctact ataaaacctt tggcatttcc ataacgctga
    10381 tacatccgca ggagcatttc tccccagtct tgtgcctcgg taccacccga acctggatgg
    10441 atttccaaga tagcgttatt gtgatcatag ggttctgata agagcaaggt catttcgtaa
    10501 gcagtcatgg ttttgtccaa ttccactaac ttttcaacca actcatcccg cacagactca
    10561 tcttctgcta gaaaatctag caaaatttca gattcatcat ataaatccaa catctgatgg
    10621 aaatttccat aagtattttt taattcattc aactcctgag acgtcttctg ggctgccaaa
    10681 ttatcattcc agaaatctgg ctccgtcatc ttgttctcaa gaatggcaat ctcttcttcc
    10741 agaccttcta agtcaaagag accccctaaa agaagttaat tttttgccaa gttcttcaat
    10801 cttttggcga atttctgctg tatccatata cacctcattt ttattcataa tctttattat
    10861 atcacatttg caagtccttg accatgttga gaaaggccgc ttgctctgct atgacatcat
    10921 cattgtctga tgaaatacct gcgataaagg aaaccatctc atcattgggc tgtttgacca
    10981 attgccccaa ggcccagata gccgttgcca tgtggaccgg attttgtttt ttatcgatga
    11041 tttctaggag tttgggaatg gcagagcgat cattactatt agccaaggct atgatggcat
    11101 tacgctggag aatatttttc ccccgccaag aacctgcaat cataccaaat ttttccttga
    11161 attgtccatt tgacaagtcc aagaatggaa tcagctcagg ctcagccaaa tcagggtcaa
    11221 tctccaccac aggtggactg gaaattccct tgttgtaagg acaacaaatc tggcaaatat
    11281 cacaaccata gatgaccgtc ttgattttct tacgaaactc caagtccatc atccccttat
    11341 cctgggtctg aaaggacaga cagcgacggg cattcatggt cgtgtcacct aatagacaag
    11401 acgtcggaca ggctgcaaca cagcgattgc aatcaccaca atcataatct actggttgat
    11461 ctggttcgat gtccaggttg gtcactaatt ctcctagaaa catataggaa ccaaattcct
    11521 tagaaatgac tagcccattc ttcccgataa agccaattcc tgcacgacga gcgaccgctg
    11581 tatccaccaa agctcctgta tctaccatag ccttgtattc caaaccatcc gtcagtttct
    11641 caattccccg tgccaaacgc tccatcttat cttgcaagat atagtggtaa tcaagccccc
    11701 atgaactagg ggtaatcttc ccacgtttgt attgggtctt ctgcggtttg acaggcaaat
    11761 gtcgaggata agctaccgcg atagaaatga tagtttttgc agattctaac gacagtttgg
    11821 gacggatacg ttcttcaata ttcttgtgtt caaatcctga cgaacgcccc tcttcctgac
    11881 tagcacgaag tgatttctcc aaataagcaa aatcatcagc cgttgtaaaa ccaatcttcg
    11941 agattccgat ttcctgagat aatttaataa tctcttcctt aatattcatt atattcattt
    12001 tagcaaactt tgaatatatt tagcaagacc tacatggcta aataagttat taatataaca
    12061 aaaaacgtta gcacaaaaca aaaaatattc atacgaacat aggccttctc ccgccaaata
    12121 ctggtcaaga catacatgat attaataccg attgctcccc ctaagccgtt agccagtaaa
    12181 tcagttatat ctgcaacccc aagtaaaaga agatattgca gaacctcaaa gcagagactc
    12241 actaacataa tcaaacatag attagtcacc cacgatgcct tgcgaaatag catttccata
    12301 taaataccaa agggaataaa acttacaata ttaaatagaa tttctggaaa atccagcact
    12361 ccatcataga ccgctgttcc tgcaaacgga attaagttta tactagcata accatagcgt
    12421 ccatatacga tgctcaagtc catcttaaag ataatcatcc aagtaagtaa aaggagatag
    12481 gcaaaaaata aaaacatact cattttcttt gtctgcatag aaattctcct ctcaactagc
    12541 atattttatc attatatcat aaatgctgtt ctataaaatg tcacttctgt gacaaagctc
    12601 gttccatatt acaagtactt tacagcctac taaaaacaga aaaggaagac actaccaagc
    12661 ctccccttat tcccaaaaat atcttactta aaatgtctga ttgctatgct gaaaagcctt
    12721 atattgatgg atttgtagca tcaaacgctc aaagttcgct tccttacatg ctcgcatgat
    12781 caagaagcaa tcaataaact tccacaaata aagtcccaaa aataacaaga acccaatcaa
    12841 gataaatagc gtaacaaaag atactgcaaa agcaatcagc ttggcaaatc ccaattcttt
    12901 attcccgaca taaaaacggt cgacaccaaa ctcaccgaag aaaatagcca aaataagagc
    12961 gacaagaggt tgacgcatct caaccatcat aagaacgttt aaagcctcat catctaaatc
    13021 ttctagttct ttttgcagaa tgaataactt atcagatggc aaataactgc ttttacttaa
    13081 aatataattc tgaagataat tcatataaac tcctacctct tcaaaattat agcagtttct
    13141 tattcttcaa gcaagcctgt aggggaaaac agtgtcagaa atcgtttaca tttttttctt
    13201 ttttgctata atgaaactag attacaagga ggttcatatg agagttatta ttcattatcc
    13261 aaaacctatc aaacaactat cctcccaaaa acttccgctc ctggtagatg gaaaaattgc
    13321 tgggacagtt actcaaggta aaattctaag cttaccaatt acacaaccat ctgttacact
    13381 aagcattcga ggggataaaa aatcgagcat tcaagttaag gagggcgata gggtctaaat
    13441 aatatagtcg aatgaattag ctttcagaca aggaactgag gcgcaggctg tactgaagta
    13501 cggcaaggcg aaagtgacga tgtatcaaag ctaattcaga tgactatgga aagtagcaaa
    13561 tacttcactc cctactattt cagcttggct atcgtaccaa tcgccttact gtttaactta
    13621 ccaactcttg tcaaaacctt cctcctcata ctagcactag ccattacttt attgggacaa
    13681 gcaatcttcc caaaatacat tatcagtaca gaaaaaagct cagaccacta aatctgagct
    13741 ttttcaaatg atatttgctt ttagtacaag gtaacgaggc gcaggctgta ctgaagtacg
    13801 gcaagtcgag ttaacgaagt aataaaagat aagctgaata actatattag atagcttttt
    13861 catccaatcc caacttacgt tgaacaaatt taacaatttc tacaacgaca accatgagac
    13921 ctgaaccgat tactgttacc atccactgag ttggtgtcaa gatagatacc ttgaagaagg
    13981 tattgaatcc tggaatcaca acagtcgcca tcaagagcaa gaaggcagct acgatagacc
    14041 agttaaagag tttgttcttg aatggaccaa cggtaaagat agattggtaa acagacttaa
    14101 cgttgaaggc atgcaccaac tgaatcaatc caagagtaac atatgccatc gtaagagcat
    14161 ccgcatgaat ggcatgatta tctccagcgt gctctgggta aagaagtgca aaaccatata
    14221 cgcccaagac aagtgctgtt tgaaggatac cttgatagat aatcgaactc aagacaccac
    14281 ctgagaagaa gcttgagtta cgaccacgag gtttgtgctg cataacacct ggttcagcag
    14341 gttcaacacc aagggcaatc gctggaagtg tatctgttac caaattgatc caaagaagat
    14401 gaactggctc caatacgtcc caaccaaaga gggtagcaag gaagatacac aatacctcag
    14461 cagtgttagc tgacaagaga tactggatgg ttttttggat gtttgagaag actttacgtc
    14521 cttcttcaac cgccacaatg atagttgcaa agttgtcatc tgcaaggacc atatcagagg
    14581 cacctttcga aacttccgta cctgtgatac ccataccgat accgatgtcg gctgtcttaa
    14641 gtgatggtgc atcgttaaca ccgtcaccag tcatggcaac aaccttacca tcattttgcc
    14701 aagccttaac gatacgaacc ttatgttctg gagatacacg agcgtatact gagtattgtt
    14761 tgaagacttt ctggaactct tcatccgtca attcgttgag ctctgcacct gtaaatacat
    14821 ggtcttctgt atcatttgga tcgatgatac caagacgctt tgcaatcgcc tcagctgtat
    14881 cttggtggtc acccgtaatc atgattggac ggatgcccgc ttccttagcg acacgaacag
    14941 cttctgccgc ttcaggacgc tcagggtcaa tcataccaac caaacctgag aagacaaggt
    15001 cgttttcaac aacgtcagat tccaattcag gaatagcatc aacatacttg taagccatca
    15061 tcaagacacg aagtgcttgc ttagccaagt ccttgttagt ggcaagaatg gcttgtttat
    15121 ccgcatcggt aatcggacga attgtaccgt tttcttcaat ttgcgttaca cgtttgagca
    15181 attggtctgg agcaccttta acagctacaa agaagtttcc agcagcttgt tggtgaacag
    15241 ttgacatcaa tttacgtgtt gagtcaaatg gcaattcagc cacacgaggc tccgatacca
    15301 agacttcacg aacgtcaaag ttttgatcca aaccaaattg aacaagtgcc gtttcagttg
    15361 ggtcaccaat caatttacca gttgggtcaa cttttgtatc gttggcaaag ttcataacac
    15421 gaagcgttgt attgcttgca tccaaagctt ctttagcatc caccaattga ccgtttgtat
    15481 agactttttc aacagtcatc tggttcatag tcaaagtacc agtcttatct gatgcgatga
    15541 tttcagttga accaagtgtt tcaacagcag gcaacttacg gatgatggaa ttacgcttag
    15601 ccaagacctg tgtaccaagt gaaagaacaa ctgttacaat agctggcaaa ccttctggaa
    15661 tggccgcaac cgcaagagct acagaagtca taagagcagg caagatacct tcaccacgta
    15721 cgaagactga aacagccatc gttaccgctg caattacaag aactgcatat gtcaagactt
    15781 ttgatagctg gtgcaagttt tgcttcaatg gtgtatcagt ctcatctgca ttagcaagca
    15841 tgccagcgat gtgcccaacc tctgtgtaca tacctgtatt tgtaaccaca ccaagaccac
    15901 ggccgtaagt aacgttagag ttttggtagg ccatgttgac acggtcaccg attggtgcat
    15961 cttcagccaa aactgcggac aaatctttat caactggtac agactcacct gtaagagctg
    16021 cctcttcgat tttgagggag ttagcttcca acaaacgcat atcggcaggg acaacatcac
    16081 ctgcttcaag caagacgatg tcacctggta ccaagtcttt agaatcaact tcgactacat
    16141 gattgtcacg aagcgcacgc gcaactgggc ttgacatgtt ttttagcgcc tcaatggctg
    16201 cctcagcttg accctcttga taaacaccaa aggcagcgtt caagataacc acggccaaga
    16261 tgataatggc atctgtcaaa ccgtgtgaac cttctgtaat caccgtcaag attgctgctg
    16321 caatcaaaat gataatcatc aagtctttga actgatccaa gaatttagct aagagtgtgc
    16381 gtttttcacc ctcatccaat tcgttacgac cgtagtctgc tagacgtttg cttgcctcat
    16441 cactagacaa accgtccaaa gaagacccca tgcttgacaa tacttgctct tcgctctgtg
    16501 tataaaacaa atcgcgtttt tgttcttttg acaatttcct tctccttctc ggtccctttt
    16561 ttacctaaca aataaaaaag agacctgttt tattaaaaca agtctcgcta tttaatatat
    16621 tgccggaaac aagtcggatt gacgacaata tcacggaatt ttccactagc tactccctcg
    16681 atttgttaac tattatatca aaaatcccga gaaattcaag aatatttttc tggaaataag
    16741 agattatttc cacgaagtaa attcccaaag taagttctag tctgtcttaa aaactggaaa
    16801 ttagactgag acaaagaaat aaggtagaac ttactatggg acaagttggt aactgacaat
    16861 gaaaaacaaa cacttaactc tctctgatcg caatgatatt caaataggaa ttgaacaact
    16921 taagcccttc tcagctatag cagctaagtt aggaaaagat ccgtccacaa tttcaaaaga
    16981 agttcggaga aatagggtga taaaagagaa ctc
//
LOCUS       DBNFCO010000044        16773 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.044, whole genome shotgun sequence.
ACCESSION   DBNFCO010000044 DBNFCO010000000
VERSION     DBNFCO010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 16773)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16773)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16773
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.044"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(<1..375)
                     /locus_tag="AC1PIV_001243"
     CDS             complement(<1..375)
                     /locus_tag="AC1PIV_001243"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIP6612267.1"
                     /translation="MITYKQNPQLDFQAVLDVYASVGWTGYTSRPEMLEKALEHSLLV
                     LATFDGDRLVGLLRAVGDGHSIVFIQDILVLPTYQRRGIGRQLLEQAVTHFPGIYQLH
                     LLTDNTEKTRSFYEAIGFTAVDS"
     gene            complement(487..1089)
                     /locus_tag="AC1PIV_001244"
     CDS             complement(487..1089)
                     /locus_tag="AC1PIV_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1648 domain-containing protein"
                     /protein_id="HIP6612268.1"
                     /translation="MKKIDIKTLFATSGIFLLIALLTIYYYGALPDTMVTHFGVNGEP
                     NGSMAKYMVTILTPLLFFCVHLFICVLYDVKGIGKTPVIRVFKWLFPLLALIIQVSLL
                     WYNLGGELDYRRLVIGLLAIGYMVIGNYLPKEELDSKTNEIERKGRKQSGYLFIIGGL
                     LLLVSLLGSPTLSILVLILFGTSVITLSLYYFYRRYKTAS"
     gene            complement(1076..1354)
                     /locus_tag="AC1PIV_001245"
     CDS             complement(1076..1354)
                     /locus_tag="AC1PIV_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="autorepressor SdpR family transcription factor"
                     /protein_id="HIP6612269.1"
                     /translation="MGLSETLKAISAPIRRQILDSLKSGPKSAGEIVEQFQLTGATVS
                     HHLSTLKKAGLILEEKQKNFIYYRLNYTVFEEVLVWIASFGGQQDEEN"
     gene            complement(1499..3043)
                     /locus_tag="AC1PIV_001246"
     CDS             complement(1499..3043)
                     /locus_tag="AC1PIV_001246"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HIP6612270.1"
                     /translation="MKFTDLQLSEDILLAVEKAGFETPSPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLNKIDTNNQAIQSLIIAPTRELAVQSQEELFKFGREKGVKVRS
                     VYGGSSIEKQIKALRSGAHIVVGTPGRLLDLIKRKALKLDGVETLILDEADEMLNMGF
                     LDDIEAIIERVPESRQTLLFSATMPEPIKRIGVKFMKEPEHVKIAAKELTNVNVDQYY
                     LRVKEHEKFDTMTRLMDVDQPELSIVFGRTKRRVDELTRGLKLRGFRAEGIHGDLDQN
                     KRLRVIRDFKNDQIDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     QSGQSITFVSPNEMGYLAIIEDLTKKRMKGLKPATAEEAFEAKKKVALKKIEREMADE
                     TIRNNFDKFKKDAIQLAAEFTPEELALYVLTLTVQDPESLPEVEIAREKPLPFKFAPG
                     QAKGKGGRGGRDRDRGGRRGDRNDRNRRDDKFKRDNRRQDNKKPHQRTSSEKKTGFVI
                     RNKGER"
     gene            complement(3476..4069)
                     /locus_tag="AC1PIV_001247"
     CDS             complement(3476..4069)
                     /locus_tag="AC1PIV_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HIP6612271.1"
                     /translation="MTQIKWRDCLLICFGAILYALVLNMLIIPHEFGEGGITGVTLLL
                     FYTTGIETSLSSFVLNGILIVLAYRFLSKLTVFYTFLAVATMSLTMHYTTFLQIKWLP
                     LIPSALLAGLVTGLSMALVIYGNGSTAGSDIIALLCNKYFKWKISTVILIFDVFVVTP
                     LAFKIGLVKTFWTLVMVVIISKSLDWFLQALKKNNHK"
     gene            complement(4147..4530)
                     /locus_tag="AC1PIV_001248"
     CDS             complement(4147..4530)
                     /locus_tag="AC1PIV_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PH domain-containing protein"
                     /protein_id="HIP6612272.1"
                     /translation="MGLFSGLLGNASQMDNDKIEQELEHVLLDNEQVEMAFSLVRDLI
                     VFTEYRLILVDKQGMTGKKVSYKSIPYRSISRFTVETSGHFDLDAELKIWISSAVEPA
                     EILQFKSDKSVIAIQKALASAVLGK"
     gene            complement(4621..7197)
                     /locus_tag="AC1PIV_001249"
                     /pseudo
     CDS             complement(4621..7197)
                     /locus_tag="AC1PIV_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647159.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            7581..8333
                     /locus_tag="AC1PIV_001250"
     CDS             7581..8333
                     /locus_tag="AC1PIV_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612273.1"
                     /translation="MENTSTQTFEELVAEQKKKRNRVLRIIITLFTTIIVFFACLALF
                     KYNSGNISGTWRNSQAEQDIVETSIKELQNQLPGIDKTWIDATYTMTVVDKKAVFTAT
                     TSFDIPKIAKLTLDQAYKVMLEEAQKEASSLGISVEEYLTTALGADYEKQLKSFLPTQ
                     AEAEKEFHKYQDEYAKELGATYNQETGTISATFFEGDVDQLFHTVTITKINDAAIKQL
                     TTYDISVKDIISYSRKGNTTIINGNEEFTLEK"
     gene            complement(8852..9382)
                     /locus_tag="AC1PIV_001251"
     CDS             complement(8852..9382)
                     /locus_tag="AC1PIV_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HIP6612274.1"
                     /translation="MKQNQLRQLTEISLFAALICVVVFFIRIPFGSQFVHLGNALVVV
                     GVLIFGAKKGALAASLGLGIFDLLSGYASVAWITILESLIVCFVLHLFYEKFLQANDS
                     LSNIMLVGIVAALTKIILNLLKYTLTGSLVGGLTPSVLFLAALGRILGTYGTAITTII
                     AVPILYQVCKRLYKRK"
     gene            complement(9379..10224)
                     /locus_tag="AC1PIV_001252"
     CDS             complement(9379..10224)
                     /locus_tag="AC1PIV_001252"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008478 - pyridoxal kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009443 - pyridoxal 5'-phosphate salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HIP6612275.1"
                     /translation="MQRLLLANDLPGVGKVALATSIPIAAACQVETMLLPTVLLSSHT
                     GGFPDVVIEDMTDLNQAYFEQWKNLNLELAGILSGYCRNPQQLSQLAMYAKQTETPLI
                     VDPIMGDSGRLYTGFTSSYVEAMKELTQSAQLILPNITEASLLTGRNYLGDSYDIHDI
                     EDLLEALAEQVSADIVLTGISFDDSQIGVAYFQQETGEITTYMSKKYPANFFGTGDIL
                     STLLAVATIQQINLHQAIPLALDFIDKSLERTLALDRDLKFGISFEPFLAELQQAFQI
                     LKEKL"
     gene            complement(10423..11112)
                     /locus_tag="AC1PIV_001253"
     CDS             complement(10423..11112)
                     /locus_tag="AC1PIV_001253"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA];
                     GO_function: GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009164 - nucleoside catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HIP6612276.1"
                     /translation="MKFGIIAAMPQELKILVEHLQDATEIDVLGRTYYQGRIGQHEVV
                     LVQSGIGKVMSAMSVAVLADRFSVDVIVNTGSAGAVAEGIAIGDVVVANQLAYHDVDV
                     TAFGYAYGQMAGQELYYPADQVLLEQLRTVLAEQEMISHVGLIVTGDSFIAGQERIAT
                     IKTHFPEVLAVEMEGAAIAQAAVNTGKPFLVIRAMSDTAQGDANITFDEFIIQAGERS
                     AQTLIAFLEKY"
     gene            complement(11121..11441)
                     /gene="macP"
                     /locus_tag="AC1PIV_001254"
     CDS             complement(11121..11441)
                     /gene="macP"
                     /locus_tag="AC1PIV_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall synthase accessory phosphoprotein
                     MacP"
                     /protein_id="HIP6612277.1"
                     /translation="MGKPLLTDEILEKVKKKQYSDQSSQFGHYRPNQDISMDDALFDP
                     YLEEDYQGYEEGQTIRIPVKPTVVKSRRIETIKREAFRSKVNKILFWVIILLIMFIIA
                     VLFI"
     gene            complement(11452..11997)
                     /locus_tag="AC1PIV_001255"
     CDS             complement(11452..11997)
                     /locus_tag="AC1PIV_001255"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016817 - hydrolase activity, acting on
                     acid anhydrides [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0009132 - nucleoside diphosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HIP6612278.1"
                     /translation="MNFEEKTIERTEIFKGHIFDVVVDDVALPNGGTGKRELIFHKGA
                     VCVLAVTPEGKMILVKQYRKAIERTIYEIPAGKLELGEEDTLEDAALRELEEETGYTS
                     DKLTLLADFYSAIGFCNERIRLYLADNLIKVENPRPMDEDEVIELHEVTLEEALNLVA
                     TGDICDAKTIMAIQYLQLMRK"
     gene            complement(12006..13388)
                     /gene="glmU"
                     /locus_tag="AC1PIV_001256"
     CDS             complement(12006..13388)
                     /gene="glmU"
                     /locus_tag="AC1PIV_001256"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003977 - UDP-N-acetylglucosamine
                     diphosphorylase activity [Evidence IEA];
                     GO_function: GO:0019134 - glucosamine-1-phosphate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006048 - UDP-N-acetylglucosamine
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HIP6612279.1"
                     /translation="MSNNYAIILAAGKGTRMKSDLPKVLHKVAGITMLEHVKRAVDAM
                     EPAKTVTIVGHKAELVQAVLEGQSEFALQSEQLGTGHAVMMAEPALAGLEGQTLVIAG
                     DTPLITGESLKNLINFHVSHKNVATILTAQADNPFGYGRIIRNADGEVQKIVEQKDAN
                     DFEKQVKEINTGTYLFDNKRLFEALKDINTDNAQGEYYLTDVISIFRQAGEKVGAYVL
                     RDFDESLGVNDRVALATAEAVMRKRINEKHMVNGVTFINPDATYIDIDVEIGAEAVIE
                     ANVVLKGQTVIGERTVLTNGTRVRDAKIAADAVISNSDIEESVIEEGVTVGPYAHIRP
                     GSLLKKDVHVGNFVEIKASTLGQGTKSGHLTYLGNATIGNNVNVGAGTITVNYDGKNK
                     FKTTVGDNAFVGSNSTIIAPVTIGDNALLAAGSVITKDIPEDAIGIGRGRQENKEGYA
                     TRFPFHPSQK"
     gene            complement(13564..14034)
                     /locus_tag="AC1PIV_001257"
     CDS             complement(13564..14034)
                     /locus_tag="AC1PIV_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HIP6612280.1"
                     /translation="MTPTQLWQEFIAINSQAGPEPEAWAFGAEADRLADLVARGIKTS
                     TSSAHALYEVEGEEIPRAGGYDIILDGQGQAVCIIQTTKVYVTPFSQVTAEHAYKEGE
                     FRQGGDLSDIKAKSLIHWRQIHEELFTIWLAEAGLSFSEDMLVVCEEFELVYPK"
     gene            complement(14031..14207)
                     /locus_tag="AC1PIV_001258"
     CDS             complement(14031..14207)
                     /locus_tag="AC1PIV_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612281.1"
                     /translation="MWQFLCGDIHDIADVQLIALVEILQFGITETLLNQIPYGFEALL
                     DQAKNWQISRKDPL"
     gene            complement(14323..15021)
                     /locus_tag="AC1PIV_001259"
     CDS             complement(14323..15021)
                     /locus_tag="AC1PIV_001259"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HIP6612282.1"
                     /translation="MTKTALITGVSSGIGLAQAGIFLENGWRVFGIDLASKPDLAGDF
                     HFLQLDLTGDLSPVFSWCQSVDVLCNTAGILDDYRPHLDISEDELAQIFAVNFFAVTR
                     LTRPYLQQMVDRQSGIIINMCSIASSLAGGGGSAYTASKHALAGFTKQLALDYAKDKV
                     QIFGIAPGAVQTGMTQKDFEPGGLADWVADQTPIGRWTQPSEIAELTFMLATGKLASM
                     QGQIITIDGGWSLK"
     gene            complement(15014..15250)
                     /locus_tag="AC1PIV_001260"
     CDS             complement(15014..15250)
                     /locus_tag="AC1PIV_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018367459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HIP6612283.1"
                     /translation="MTFEEILPGLKAKKKYVRTGWGGAENYVQLFDTIEVHGQKLEAT
                     PYFLINVTGEGEGFSMWSPTPCDVLATDWVEVHD"
     gene            complement(15310..16131)
                     /locus_tag="AC1PIV_001261"
     CDS             complement(15310..16131)
                     /locus_tag="AC1PIV_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612284.1"
                     /translation="MKRDKQVLRDKTNIIVDNLLPENKAYFDEIRDYMILKSFFKDEK
                     AILEQIYSMVSDFKMAEVDGLTAVDFFGTDPKDMADQLLKNAPKAPLREMTITYFSAV
                     ATLYAIGTFLLFANTGQFQLEFILFLASCTNALLLCWLVFGLLPSVLFKPKASKMIIG
                     LIVLTIIILFNIIFNLPAMIGDKAIYLKFPEMFDWLFVIVTSLATIVFSVKVKVFRTF
                     ALPIFAFLLIGIIKKLLVMNLVSGDLWTVWLPIGLLCAAMILFYLQIYQSTKEST"
     gene            complement(16118..16453)
                     /locus_tag="AC1PIV_001262"
     CDS             complement(16118..16453)
                     /locus_tag="AC1PIV_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HIP6612285.1"
                     /translation="MKETQMLKGVLDGCVLQIISQKEIYGYELVQELRKQGFENMVGG
                     TAYPLLQKLEKNGYIIGEIKPSSDGPDRKYFTITQDGESYLRDFWREWSSLVEKVGTI
                     QKGIFNETR"
     gene            complement(16450..16614)
                     /locus_tag="AC1PIV_001263"
     CDS             complement(16450..16614)
                     /locus_tag="AC1PIV_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612286.1"
                     /translation="MKLEKKSRENWKLAGITLVTAIITGWALDSILILGILLGSGLLF
                     GFFTDDEEGL"
BASE COUNT         5019 a         3678 c         3004 g         5072 t
ORIGIN      
        1 gctatcaacg gctgtaaagc caattgcctc atagaaagac cgtgttttct cagtattgtc
       61 cgtcaagaga tgaagctgat aaatacccgg aaagtgggta acggcctgct ccaaaagctg
      121 acgcccaatt cctcgtcgct gataggttgg taggaccaag atgtcctgaa taaaaacgat
      181 tgaatgcccg tcgccaactg ctcgcaagag acccactaga cggtcaccgt caaaggtagc
      241 aagaacgagc agactatgtt ccaaggcctt ctctagcatt tctggacggc tagtatatcc
      301 tgtccaacct acagaagcat agacgtcaag gacagcttga aaatcgagtt gaggattttg
      361 tttgtaagta atcatgtctt tctcctttgt attgtttttt agaatacaaa ggctttgtcc
      421 attgttaaaa cgcccatggt ctttcctcct gttttgctac atttagtata acaaaaactg
      481 ctccaattat gaagcagttt tgtaacgacg ataaaaataa tagagactca aggttatgac
      541 agatgtacca aacaaaatca gcacaaggat agatagggtt ggtgagccta atagactaac
      601 tagcagcaat aacccaccaa taatgaagag atagcctgac tgctttcttc cctttcgttc
      661 tatttcattg gtcttgctat ccaattcctc cttgggtaaa taattcccta ttaccatata
      721 gccgatagcc agcagtccaa tgacaagcct acggtaatcc aattctccgc ctaaattata
      781 ccagagtaaa gaaacttgaa tgatgagagc cagtagcgga aaaagccatt tgaacactcg
      841 aatgactggt gttttcccta tccctttcac atcataaagc acacaaataa ataggtgaac
      901 acaaaagaat agtagcggtg tcaaaattgt caccatatac ttagccatag agccatttgg
      961 ctcaccattt acgccaaaat gcgttaccat ggtatctggc aatgctccat agtaataaat
     1021 cgtcaataaa gcaatcagta ggaatatacc agaagttgca aataaggttt ttatgtcaat
     1081 tttcttcatc ttgttgccct ccaaaacttg caatccaaac caagacttct tcaaagaccg
     1141 tatagtttag acgataataa ataaaatttt tctgcttttc ctccaaaatt aatccagctt
     1201 ttttcaaagt ggataaatga tgagaaactg ttgctcctgt taattgaaat tgttctacaa
     1261 tttccccagc agacttcggc cccgacttaa gactatctag aatttgccta cgaataggag
     1321 cagaaattgc cttcaaggtt tcagacaatc ccataataag cctccttgtc catctattta
     1381 gaaatatttc taaatagaat tatactctgt ttttattgtt tgtcaagaac tatttcgatt
     1441 attttctaaa tagatttcaa aaaaaacaga ccactcttta tggtctgtca aatccggctt
     1501 atctctcccc tttattgcga atcacaaagc ctgttttctt ttcacttgat gtgcgttggt
     1561 gtggtttttt gttgtcttga cggcggttat cgcgcttgaa cttgtcatcg cgacggttgc
     1621 ggtcgttacg atcaccacgg cgtcctccgc gatcacggtc gcgacctcca cgtccacctt
     1681 tacccttggc ttgaccaggt gcaaacttga atggtaatgg tttttctcgc gcaatttcta
     1741 cctctggcag actttctgga tcctgaacag tcaaggtcaa tacataaagc gctaactctt
     1801 caggggtaaa ttcagccgct aactgaatag catctttctt gaacttatca aaattgttac
     1861 ggatggtttc atccgccatt tcacgctcaa tcttcttcaa agcaactttt ttcttggctt
     1921 caaaggcctc ttcagctgtc gctggcttga gccctttcat gcgtttcttg gtcaaatctt
     1981 cgataatagc caagtagccc atctcgtttg gcgaaacaaa ggtaatagac tgacctgatt
     2041 gacccgcacg acctgtacga ccgatacggt gaacatagct ttctggatcc tgtggaatat
     2101 cgtagttata gacatgcgtt acaccagaaa tatccaaacc acgcgccgca acgtccgtcg
     2161 caacgaggac atcaatctgg tcatttttaa agtcacgaat aacacgaaga cgcttattct
     2221 gatccaaatc tccgtggata ccctctgcac ggaagccacg cagtttcaaa ccacgagtca
     2281 attcatcaac acggcgctta gtacgaccga agacgataga caattctggc tggtcaacgt
     2341 ccatgaggcg tgtcatggtg tcgaattttt catgttcttt gacacgaaga taatattggt
     2401 caacattgac attagtcaat tcctttgctg caatcttaac gtgctcaggc tctttcatga
     2461 atttgacacc aatacgcttg attggctctg gcatggttgc agaaaacaga agagtttgac
     2521 ggctttctgg cacacgttcg atgatggctt caatatcatc caagaagccc atgttgagca
     2581 tttcatcagc ctcatcaaga ataagggttt caacaccgtc aagcttgaga gctttacgtt
     2641 tgatcaagtc caagagacga ccaggtgtac caacaacaat gtgagcacca gaacgaaggg
     2701 ccttgatttg tttttcaatg ctagaaccac cgtaaacaga gcgaactttt actccttttt
     2761 cacgaccaaa tttgaaaagc tcttcctgac tctgcaccgc caactcacgc gttggggcga
     2821 taatcaagga ttgaattgct tgattgtttg tatcaatctt gttgagggtt ggcaaaccaa
     2881 aggctgcagt tttccctgtc cccgtctgcg cttgaccaat cacatctttt ccttccagag
     2941 caagcggaat ggtctgctcc tggattggtg acggcgtttc aaaaccagcc ttctcaacgg
     3001 caagcaaaat atcttctgat aattgtaaat ctgtaaattt caatgtattc tcttttctaa
     3061 aaggcagtgc gaagctacct tatctaactt ttttgtaaca agatatcagg gtcgaaccac
     3121 tgatattgga tttgcaactt accaagtata acacaatcta acaataatag ttaatattta
     3181 cctttaaaaa gtcaataata cgttttcatg aggagtccat cattttatag acatttgaat
     3241 tagctttgat acatcgatac tttcggtttg ccctactcta gtaccagctc cttgtctgaa
     3301 agttatactc ttcgaaaatc aaaatcagac gttgttgact tgatttgatg aacttcagtt
     3361 ctatctgcat ctgcgtcgcc tagtctgttt ttgattttca ttgagtatta attcattcga
     3421 ctataagaaa agagaaacct agttatacat gcacaactag gtttctcttg tatttttatt
     3481 tatgattatt ctttttcaat gcttgcaaga accagtccaa acttttactg ataatgacaa
     3541 ccattaccaa tgtccaaaat gtttttacaa gcccaatttt aaaagccaaa ggagttacca
     3601 caaatacatc aaaaatgaga ataacggtgg aaatcttcca tttgaaatat ttattacaca
     3661 acaatgcaat aatatcactt cctgccgtgg acccgtttcc ataaatgact agagccattg
     3721 ataaacctgt caccaatccc gccaagagag cagagggaat caggggcaac cattttattt
     3781 gcagaaaagt cgtataatgc atggttaagg acatagtagc aaccgctaag aaagtataga
     3841 aaaccgttaa cttactcaaa aagcgatagg ctaatacaat caaaatccca ttcaaaacaa
     3901 aactggacag acttgtttca atccctgtcg tataaaacaa aagtagggta acaccagtaa
     3961 tcccaccttc gccaaattca tgtggaatga tgagcatatt caaaacaagg gcatatagga
     4021 ttgccccaaa acatatcaat aagcagtctc tccattttat ctgcgtcata ttctctcctc
     4081 acaaacagtc caccttagta tatcaaaaaa agcagaaagc ggatagccac tttctgtact
     4141 tttttcctat tttcctaaga cagctgaagc cagagctttt tgaatagcaa tgacactctt
     4201 atcgctctta aactgaagaa tttcagcagg ttcaacagcc gatgaaatcc atattttcag
     4261 ctcagcatct aagtcaaaat gaccagaggt ttctaccgta aaacgtgaaa tcgagcggta
     4321 aggaatcgat ttataagata cctttttccc agtcattcct tgcttatcga ccaaaatcaa
     4381 tcgatattct gtaaaaacaa tcagatcacg aaccagacta aatgccatct caacctgttc
     4441 attatccagt agaacatgct ccaattcctg ttcaatctta tcattatcca tttgcgaggc
     4501 attgcctagt aaacctgaaa atagtcccat aatatgactc ctttggtatt tttctatagt
     4561 ataacacaaa aagctactag ttgactatct taggcactag gtctttacca aacatgagaa
     4621 ttactcgctt acctttgctt ccttatcaac ttctttaggt tgattgttct caatactgcc
     4681 accttcaact gctggaaaat gttctgcaat cgcagatggg atcttctgat catttagatt
     4741 taattcttcc ttcggaatgt gattttcact cacatcaatt gttttcaaag tcttattcgg
     4801 ctctgtaatg gcaagtgttt caatatcatt ttttgaagca ttcaggtctt ctaaggcttt
     4861 gtaatcattg actccttcta aattcttcaa ttgattatct gcaacattta atcgaacaac
     4921 cgattcttgt ttaccctcta tttccaaagt cttaatttga ttcccctcta catccagatt
     4981 tactaatttt tcattttctt ctatcccttg taattcagta atcttattat tcttaagagt
     5041 aagactagtt aaatttggat tgttttttac aaactgaaga tcttttacat tactttcatt
     5101 agctgtcagt tcttctaaat tctctgtttt tagagttgat atatccaatt gaggattctg
     5161 tgatatatac aaacgggtta acttcttctt gttttgaagc gcagataaat ctgtgatacg
     5221 attattatct aaactaacag ctgtcaattg tgacaaatct gctaatgggg ataaatccgt
     5281 cactttatta tgatctaaat ttaaagattc caaagctttt aatttagcta gaatagtgat
     5341 atcttcaatg tcatttcctg cagcagaaac tacttttaag tttggaaatt cttccaaaaa
     5401 gcccaaatca gaaacaccat tttgtgataa gtcaattccc tctaatgttg gaatttcttt
     5461 caaaaattga taatccttaa cgcctgtgct agtcatccat aattgtttca attttttaaa
     5521 ttgcaagata ggttttacat catcaattgg cgtaaaacca atccctaaca cttcaacatt
     5581 tggcatcaag tccagaccgg ctctctttag cggatctttt cgctgaccaa tatttagata
     5641 ttttaccgtt tttaaccact ctctcatctt ctcggaatct gtttcattag atgggaaagg
     5701 agtatcggcc gtagcatgca aaatatcttc aataatctca tcatcaaaac ctaattgttt
     5761 taaagtagcc attccaattt tatcatgagc atgtgggtca ccgtgagggt cttcgattgg
     5821 ttttccaact tcaactttct caatcaagat tgtatgagaa tggtcaccat gagggtaaac
     5881 gaaagcaggt cctgcatctg tttctatcac cttgattttt gcttttgaaa catgcaggtt
     5941 ttcggctagg tagctctttt tagcttctcg ttcttcttct acacttgagt taggtttccc
     6001 accttcttgt ggtgacaacg gaatttctac attaacttga gtggaagttg acgaatggta
     6061 ttctgctcta gcagtctcta aatactgagt aggaatataa gactcccacg gacttcctat
     6121 caaatgactg tacggaagta aatgagtatg agtaccatgg ccaatgagta accctaacgc
     6181 tgtttgacct tagactccgc taccatcaaa aaggaaaccg tcgcttgttg gataatcaat
     6241 acctgggaaa gctttctttg aattagactg agtggaagta tgcccttttt ctgtggtaga
     6301 cttgagtggg acgaaattat ttcttgtggt cggagtatgc aacgaatgat tatcaagaac
     6361 agtaatctgt cccttttttc caatggtctc cccagtattt ccttgtccgt attgcaaact
     6421 tgatttccaa atataatgat aatgatctcc atgacgtacc gtatagccat tcgcatcttc
     6481 agccactaca tccttcggat caaatacata accatcatca aaagtttgtg atagcttcgc
     6541 ttgctttgcg ttggaatgcg agctggattg gctattctca atgtactctt tgggtaccag
     6601 ataggaccat ttgctttctt ttaaatcctt atagaagata aaatgtgaat gaccattatg
     6661 ttctaagacc agtccctcat ccgtttttga aagaatttga ccttcatttt caaaaagaaa
     6721 tccatcatcc gtaggataat caacaccagc tacccctttt ttagcttgag aagtaggttt
     6781 cttttgattt ttggtgagtt tcttagcttc agaaatagaa attacattag catctttatc
     6841 cttgggatag tagaagtact gctcatttac ttttataata taacctttct ctagctgata
     6901 ctgaatatct tctttattca atttataatc agaatctgga agggtatctt ttaaaaagtg
     6961 tgccgcatac gggatcggac cttcaaaaaa gtatgactct tctccatata gacgcatata
     7021 gccattagat ttaatttcag acactacaat cgtattttca tctacttttg agatattgct
     7081 actttgaaca tcttgatgat ttattgcagt attctctgtt ttttggcaac ccgccaaaaa
     7141 aagatgacaa gataggataa tgcctgtcaa ggcaaataag gttgttttct ttttcatttt
     7201 tgtcctccta agctcattaa ccagttaaca attaactagt atacatttta tttttgattt
     7261 ttgcaagaaa aaacaactga caatgattgt tcgtgaataa attttccatt ccacgacaaa
     7321 cgcatgaaaa atttgtttta taaaccatat tttcacgact gctgtcagtt tttagtagaa
     7381 aaaatgtaat ataatagcct tggaaatggg ggtatccttg ttaaagtgca agttttacaa
     7441 aaaccttaaa aaaatgcata caacaagaaa atagttacat acctttttct tcatgcggat
     7501 tgcatgtttc catccctacg atcattgaca aagcaaacaa actatagtat attaaaaata
     7561 gggaaataaa aggagaatat atggaaaata catctactca aactttcgaa gaactcgttg
     7621 cggaacagaa aaagaaacgt aatcgcgtcc ttagaattat tatcacactc tttaccacta
     7681 ttatcgtatt ttttgcctgt cttgcattat tcaaatacaa cagtggcaac attagcggta
     7741 cgtggcgtaa ttcccaagct gaacaagata ttgtcgaaac cagtatcaag gaattgcaaa
     7801 atcaacttcc aggtattgat aaaacgtgga ttgacgcaac ttatacgatg acagtcgtag
     7861 ataagaaagc tgtcttcacc gctacaacaa gctttgatat tcctaaaatc gcaaaattaa
     7921 ccttggatca agcttacaag gtaatgttag aggaagcaca aaaagaagca agttctctgg
     7981 gaatttccgt agaagaatac ttaacaaccg ctctcggagc agattatgaa aagcaattga
     8041 aatcatttct acctacacaa gctgaggcgg aaaaagaatt tcataagtac caagacgaat
     8101 atgctaaaga actaggtgcc acatacaatc aagaaactgg tactatctct gctacctttt
     8161 tcgaaggaga cgtcgatcag ctcttccata ctgtgaccat tacaaaaatt aatgacgcag
     8221 caatcaaaca gctgactaca tacgatattt ccgtaaaaga tattatttcc tattctcgca
     8281 agggaaatac caccattatt aacggaaatg aagaatttac tttagaaaaa taataaaaaa
     8341 agctgggaaa gtcatccctg atggttccga cctcacccac agaataatga aaataaatat
     8401 gaagccctca ctaggtgtat aatcttagtg agggctttgt gcttgatgag ttaatgatgt
     8461 tagtcatcgc cggaaaaact aacccactct attgacgagc tctaaaaaat atgcaataga
     8521 catgagcata agaactagcc aataaaaaca cagatagatt caagctaatt ttgatgaaat
     8581 acagccgaat tgtctgtgct tttatttttg tctctactat agataggaca acattgtgac
     8641 gatatttgaa agaacttgta ctaatactca atgaaaatca aaagtagcct aggaaacgaa
     8701 gccgaagata gaactggagt tcatcaaggc aagttgacaa cggataattt tgattttcgt
     8761 agagtataac ctcctgtttg tttcatcact tacagtgtag tccttctgac cttttttgca
     8821 tattgaattt aactaatgtc accaatataa attattttct cttatataac cttttacata
     8881 cctgataaag aataggtaca gcaatgatgg tcgtaattgc agtgccatag gttcctaaaa
     8941 tcctacctaa agcagctaaa aataatactg atggcgttag tccaccgact aaactacccg
     9001 tcaatgtgta cttcaacagg ttcaagataa tttttgtgag ggctgcaact atcccaacca
     9061 acataatatt tgatagacta tcgtttgcct gtaggaattt ctcataaaat aagtgtagga
     9121 caaaacagac aatgagtgat tctagaatgg taatccaagc aacggaggca tatcccgaca
     9181 gtaaatcaaa gattcctaga ccgagtgagg ctgccagcgc cccttttttg gcaccaaaga
     9241 ttagtactcc tactaccacc agagcattgc ctagatggac aaattgactc ccaaaaggaa
     9301 tacgaataaa gaagacaacc acacaaataa gggctgcaaa taggctaatt tctgttaatt
     9361 gacgcaattg attctgtttc ataatttctc ctttaatatt tgaaatgcct gctgtaattc
     9421 tgctagaaaa ggttcaaagg aaatcccaaa tttcaagtct ctatccaaag caagggtacg
     9481 ctctaaactc ttatcgataa aatctaaagc tagagggata gcttgatgga gattgatttg
     9541 ttggatggtt gctacagcca acaaggtaga tagaatgtca cctgttccaa agaaatttgc
     9601 tggatatttt ttagacatat aggtagttat ttcccctgtt tcctgctgaa aataggctac
     9661 acctatttgg ctatcatcaa aggaaatccc tgtcagtaca atatctgcgg atacctgctc
     9721 tgctaaagct tccagtaagt cctcaatatc atgaatatcg taggaatctc ccaaatagtt
     9781 tctcccagtc aatagagaag cttctgttat attcggaaga atgagctggg ccgactgagt
     9841 caattctttc atggcctcta cataggatga tgtaaaacct gtatacagtc ttccactgtc
     9901 acccataatc ggatctacaa tcaatggtgt ctctgtttgt ttagcataca tagccaattg
     9961 acttagttgc tgaggatttc tacagtagcc agacaagatg cctgccaact ccaaattcaa
    10021 gttcttccac tgttcaaaat aggcttgatt caagtcagtc atatcttcaa tgacaacatc
    10081 tgggaaaccg cctgtgtgtg aggataaaag aactgtaggt aaaagcattg tttctacctg
    10141 acaagctgct gcaattggga tgctagttgc tagtgcaacc ttaccaacac caggtaagtc
    10201 gttcgcaagc aataatcgct gcatgataac tacctcctaa attatttttc ataaacaaaa
    10261 ttgtaaagga ttatcataca tttttcaatc ttacatatcc gcaactgtat ggggacagat
    10321 agctgaaacc ttgcaacacc aggctcaaat tattacataa gaaaaacagc aacaactctt
    10381 tgctactgtc atcctcttca atgtattgtt gtcaaattct gtttaatatt tctccagaaa
    10441 ggcaatcagg gtctgggcag aacgttctcc tgcttgaatg ataaattcat caaaggtgat
    10501 attggcatct ccctgagctg tgtcactcat ggcacggata accaagaatg gcttacctgt
    10561 attgacagct gcttgagcga tagctgctcc ttccatctct acggcaagga cttctgggaa
    10621 atgagttttg attgtagcga ttctctcctg acctgcgata aaactgtcac ctgtcacaat
    10681 cagacccaca tggctaatca tttcctgctc tgctaaaacg gttcttagct gttctaacaa
    10741 gacttggtcg gctggataat acaattcctg ccctgccatt tgcccgtaag catagccgaa
    10801 agccgtcaca tccacatcgt ggtaagccaa ttgattcgct acaaccacat caccgatggc
    10861 aataccttca gcaacagctc ctgccgaacc tgtattgaca atgacatcaa ccgaaaatcg
    10921 atctgccaaa acagccacgg acatagctga cataacctta ccgatacctg actgaacaag
    10981 aacgacttca tgttgaccga ttcgtccctg atagtaagtt cgacccaaga catcgatttc
    11041 agttgcatct tgtagatgct cgaccaaaat ctttaattcc tgaggcatgg ctgcgataat
    11101 tccaaatttc atctcttctc ctaaataaat aatactgcaa tgataaacat tatcagtaag
    11161 atgatgaccc aaaaaaggat tttgtttacc ttactgcgga aagcttctcg cttgatggtt
    11221 tcgatacggc gactttttac tacagtaggt ttgaccggga ttcggatcgt ttgtccctct
    11281 tcatatccct gataatcttc ttctagatat ggatcgaata gagcatcatc cattgatata
    11341 tcctggtttg gacgatagtg tccaaactgg ctagattggt cggaatactg tttctttttc
    11401 actttctcta aaatttcatc cgtcaacaag ggcttgccca ttgctagttt cctactttct
    11461 catgagttgt aaatattgga tagccatgat ggtctttgca tcacaaatat cgccagtagc
    11521 caccaagttc aaagcctctt ccaaggttac ctcatgtaat tcgataacct catcttcatc
    11581 cattggacga ggattttcaa ccttgataag gttatctgct aaataaaggc gaattcgttc
    11641 attacagaaa ccgatggctg aatagaaatc tgccaacaag gtcaatttgt cactagtata
    11701 gcctgtttct tcttctaatt cacgcaaagc agcatcttca agcgtatctt cttcgcccag
    11761 ctccaatttc cccgccggaa tttcataaat agtacgttca atggccttgc ggtattgttt
    11821 gaccaaaatc attttacctt ctggggtaac ggctaaaacg caaactgctc ccttgtggaa
    11881 aatgagttcg cgcttaccag ttccaccatt tggcaaggca acatcatcta ctactacatc
    11941 aaaaatgtgc cctttaaaaa tttctgtccg ctcaatggtt ttttcttcaa aattcatatg
    12001 attacctatt tttgacttgg atggaacgga aaacgagtcg cataaccttc tttgttttct
    12061 tgacgaccac gaccaatacc gatggcatcc tctggaatgt cttttgtaat gacagaacct
    12121 gcagccaaca aggcgttgtc cccaatagtt actggtgcga tgatggttga attagagcca
    12181 acaaaggcat tatctccaac ggttgtttta aatttatttt taccgtcgta gttgacagta
    12241 atggtaccag caccaacgtt aacattattg ccaatcgttg catttcctag gtaggtcaaa
    12301 tgaccagact tcgttccttg accaagtgta gaggccttga tttccacaaa gtttccaacg
    12361 tgaacatctt ttttcaagag actacctgga cgaatatggg cgtatggtcc taccgtcaca
    12421 ccttcttcaa taacagattc ttcaatgtct gagttgctga tgactgcatc tgctgcaatt
    12481 ttggcatcac gtacacgagt accattggtt aaaacagtac gttcaccaat caccgtttgc
    12541 cctttcaaga caacattagc ttcgataaca gcttctgcac caatctcaac atcaatatca
    12601 atataggttg catctgggtt gataaatgtc acaccattga ccatgtgttt ttcattgatt
    12661 cgtttgcgca taacagcttc tgcagtcgca agagcgacgc gatcattgac acccaaactt
    12721 tcatcaaaat cacgcaatac ataggcacca accttctcgc ctgcctgacg gaaaatcgaa
    12781 ataacatctg tcagatagta ctcaccttgg gcattgtccg tattaatatc tttaagcgct
    12841 tcaaaaagac gtttattatc aaacaagtag gttcctgtat tgatttcttt cacttgtttt
    12901 tcaaaatcgt tggcatcttt ttgctcaaca attttttgca cttcaccatc agcattgcga
    12961 ataatccgac catatccgaa tgggttatca gcctgagctg tcaagatagt cgcaacattc
    13021 ttgtggctga catggaagtt aataaggttc ttcaagcttt ctcctgtaat cagcggtgta
    13081 tcccctgcga taacaagggt ctgaccttcc aaacctgcaa gagctggctc agccatcata
    13141 acggcgtggc ctgtccccaa ctgttcagat tgaagggcaa actctgactg accttcgaga
    13201 actgcttgga ccaattctgc cttgtgaccg acaatcgtta ctgttttagc aggttccata
    13261 gcatctacag cccgtttgac atgctccaac atggtaattc ctgccacttt gtgtaagacc
    13321 tttggcaagt cagacttcat gcgagttccc ttacccgccg ctaggataat tgcatagtta
    13381 ttgctcatag ttttctctct tttcaatgat ataccctatt atagcaaatt ttgatgtttt
    13441 tggaaaatag caatattata gggaattttc gtaaataaaa aagaaactgg aatgaagcca
    13501 gtttctcaaa aatttctagt attagaaaac aaactacagg ttgattgcat cctatagaat
    13561 tgtctattta ggataaacca attcaaattc ttcacagacg accagcatat cttctgagaa
    13621 ggacaggcct gcttctgcca gccagatagt gaaaagctct tcatggatct gtcgccagtg
    13681 gatcagactt ttcgctttta tgtcagacaa gtcacctccc tgacggaact cgccctcctt
    13741 gtaggcatgc tctgctgtca cttgggaaaa gggcgtcaca tagaccttgg tggtctggat
    13801 aatgcaaaca gcctgacctt gtccgtccag aatgatgtca tagccaccag ctcttgggat
    13861 ttcttctccc tctacttcat agagagcatg ggcagagctg gttgaagttt tgatgcctct
    13921 agccaccaaa tcagccagtc gatcagcttc cgccccaaag gcccaagcct ccggctcagg
    13981 acctgcttgg gaattgatgg caatgaattc ttgccagagt tgtgtcgggg tcataggggg
    14041 tcctttctag aaatttgcca attcttcgct tgatcaagta aagcctcaaa tccataaggg
    14101 atttgattta gaagtgtttc ggttatccca aactgaagta tctcaactaa agcaattaat
    14161 tgaacatctg caatgtcatg aatatctcca caaagaaatt gccacatccc atcttccaag
    14221 tcatgactga tgtaggttat cggtttattc tcttcactat gtgtttacag atcactactg
    14281 ctacatgagg attatcatca aaaatcaaca tcactttcct ccctacttca aactccagcc
    14341 accgtcaatg gtgataatct ggccttgcat ggaagcgagt tttccagtag ccagcatgaa
    14401 ggtcagctct gcgatttcgc ttggttgggt ccagcgtccg ataggggtct ggtctgccac
    14461 ccagtccgcc agaccaccag gctcaaagtc cttctgggtc atgcctgtct ggacggcacc
    14521 aggagcgatg ccgaagatct ggaccttgtc cttggcatag tccagtgcca actgcttggt
    14581 aaaacctgcc aaagcgtgct tggaagcggt ataggcagag ccacctccac ctgctagact
    14641 ggaggcaatg gagcacatat tgataatgat gccagactgt ctgtccacca tttgctgcag
    14701 ataggggcga gttagtctag tcaccgcaaa aaaattcacc gcgaagatct gagctaattc
    14761 gtcctccgaa atatcgaggt ggggtcggta atcgtctaaa atgcctgcgg tgttacagag
    14821 gacatcgact gactggcacc aggaaaagac gggcgataaa tcgcctgtca ggtccagctg
    14881 tagaaagtgg aaatcgcctg ccaaatcagg cttgctagcc agatcaatcc cgaagacacg
    14941 ccagccattt tccaaaaaaa tccctgcctg tgctagacca atgccgctgg aaacgccggt
    15001 gatgagggct gtcttagtca tggacttcta cccagtcggt cgcaaggaca tcgcaagggg
    15061 tcgggctcca catggagaag ccttcaccct cgccggtcac gttgatgagg aaatagggcg
    15121 tcgcctctag cttctgcccg tggacctcga tggtgtcaaa gagctggacg tagttctccg
    15181 ccccacccca gcctgtgcga acgtactttt tcttggcctt caagcctggt aaaatctctt
    15241 caaatgtcat gattattcct tttcttattt attttaacac aaatgttttc agtaacgaat
    15301 aagagttagc taagtactct cttttgttga ttgataaatc tgtagataga ataaaatcat
    15361 ggcagcacat agaagaccaa tcggtagcca aactgtccat aaatcaccac taaccagatt
    15421 catcaccaat aattttttga taatgcctat cagtaaaaaa gcaaaaatcg gtaaagcaaa
    15481 ggttctgaat actttcacct taacagagaa aactatcgtg gccaaacttg tcacaatcac
    15541 aaataaccaa tcgaacattt ctggaaattt caaatagatt gccttatctc caatcattgc
    15601 tggtaaattg aaaataatgt taaaaagaat aattattgtt aggacaatca agcctataat
    15661 cattttagaa gcctttggct taaaaagaac agatggtaac agaccgaaaa ccagccaaca
    15721 aagcaacaaa gcattggtgc aagaagccaa aaacaggatg aattctaatt gaaattgtcc
    15781 cgtgtttgca aacaaaagga aggtgccaat ggcgtacaag gttgcgaccg cactgaaata
    15841 ggttatcgtc atttccctca agggagcctt cggtgcattt tttaaaagtt gatctgccat
    15901 atctttgggg tctgttccaa aaaaatctac tgctgttaga ccatcaacct cagccatttt
    15961 gaaatcactg accatactat aaatctgttc caaaatcgct ttttcatctt taaaaaagga
    16021 tttcaaaatc atatagtcgc gtatctcatc aaaataagct ttattttcag gtaacaaatt
    16081 atctacaatt atatttgtct tatctcgcaa gacttgttta tcgcgtttca ttaaatattc
    16141 ctttctgaat ggttcctact ttttctacaa gacttgacca ttcccgccaa aaatccctta
    16201 aataactctc tccatcttgg gtaatcgtaa aatatttacg atctggcccg tccgatgatg
    16261 gttttatctc gccaatgata taaccattct tttctaattt ttgcaagaga ggataggcag
    16321 ttcccccgac catgttttca aagccctgtt ttctcaattc ctgaaccagc tcataaccat
    16381 aaatctcctt ctgactgata atttgtaaga cacagccgtc taggaccccc tttagcattt
    16441 gggtttcttt cataagccct cctcatcatc tgtaaaaaat ccaaacagta aacctgatcc
    16501 taacaggatg cctaagatca aaatagaatc caaggcccag cctgttataa tggccgtcac
    16561 aagcgtgatt cctgctagtt tccaattttc ccgacttttc ttctccagtt tcatactgcc
    16621 tccctaccta gtttgtaata ccgactagtt tgataaaaat aaaagtgatt ttctttgtct
    16681 tctatcacta gtttgtttta cctattagct ttgtatctat agtctaacac aaggtggcta
    16741 gtttgtaaaa caaaatagtg aaaaatattc aaa
//
LOCUS       DBNFCO010000045        16280 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.045, whole genome shotgun sequence.
ACCESSION   DBNFCO010000045 DBNFCO010000000
VERSION     DBNFCO010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 16280)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16280)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16280
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.045"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(282..2933)
                     /locus_tag="AC1PIV_001264"
     CDS             complement(282..2933)
                     /locus_tag="AC1PIV_001264"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HIP6612287.1"
                     /translation="MSKELSPKYNPAEVEAGRYQTWLDQDVFKPSGDAEAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLREQG
                     VTRYDLGREKFLDKVWEWKDEYAATIREQWGKLGLSLDYQRDRFTLDEGLSKAVRKVF
                     VELYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALQVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIVNKPIPIVADEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAGEFAGMDRFEARKATVAKLQELGALV
                     EIENRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTADKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNESGEMYVGEEAPAGDGWVQDEDVLDTWFSS
                     ALWPFSTMGWPDENAADFQRYFPTSTLVTGYDIIPFWVSRMIFQGIEFTGKSPFKNAL
                     IHGLIRDEEGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLDAARENVAKVAAGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEAEKVMTRSVLLYTLDQI
                     LRLLHPIMPFVTEEIFAQYAEGSIVVAAYPVVNPAFENAEAHKGVESLKDLIRSVRNS
                     RAEVNVAPSKPITILIKTADSELETFFKANENYIRRFTNPEQLEISSSIAAPELAMSA
                     VITGAEIFLPLADLLNVEEELARLDKELVKWQKELDMVGKKLSNERFIANAKPEVVEK
                     EKEKQADYQAKYDATVARIEEMKKLVK"
     gene            complement(3048..3623)
                     /locus_tag="AC1PIV_001265"
     CDS             complement(3048..3623)
                     /locus_tag="AC1PIV_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HIP6612288.1"
                     /translation="MNLIIIGAQASGKMTVGQEVAKLTGMTLFHNHDSIDFSLRFIPE
                     FSEDMFDLNTRITFAVYDVFARSGRPLIGTALINFKNLIEVQFLTTVQTIFHHHGQEI
                     LFVELETALEERLRRNRTENRLTHKPLKRHIEVSEAEILSTADTCRYTSLGIPEGIQH
                     YLKINNTHLSANDVAQLIIQKMEELEQEQTK"
     gene            complement(3620..4009)
                     /locus_tag="AC1PIV_001266"
     CDS             complement(3620..4009)
                     /locus_tag="AC1PIV_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HIP6612289.1"
                     /translation="MLHHVEIYVSDLETSRAFYDFLLTKLGYSLYQEWDKGLSYKKAE
                     QYLVFVQTPEDFLEVGYHRCRTGLNHLAFHAGTPDEIDQWRKEFLTRRVKLLYDDRYP
                     HAGGPDHYALYLEDPDGIKIELVGEGV"
     gene            complement(4251..4637)
                     /locus_tag="AC1PIV_001267"
     CDS             complement(4251..4637)
                     /locus_tag="AC1PIV_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HIP6612290.1"
                     /translation="MAKKKVNRKKQLKKQLADLKRAGRVGLERAAEVVETVAHKAEAV
                     VERTVEQVKEVVAEVTSSATSLEDFLALPELEGIAAARLETFYEAGIQSVADFANHTE
                     KELLALKGIGPATIKQLKEKGIELKA"
     gene            complement(4652..4906)
                     /locus_tag="AC1PIV_001268"
     CDS             complement(4652..4906)
                     /locus_tag="AC1PIV_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HIP6612291.1"
                     /translation="MTKEQEFLKEFEAWVNTQVMVNEMAVEESRRVLEEDKDERAADA
                     YIRYESKLDAYRFIQGKFANYHAGKGFHDLPDELFGQRHY"
     gene            complement(5016..6017)
                     /locus_tag="AC1PIV_001269"
     CDS             complement(5016..6017)
                     /locus_tag="AC1PIV_001269"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HIP6612292.1"
                     /translation="MIEVKTFDEKAKLYCLENKNGMQVTLTDFGARVVEVLLPVEENG
                     GLRNVSLAAKSDDDYRKTDLYPGSTIVPVAGRISGAQAEIEGTSYHFTENEPGRTLHG
                     GVDTANEQYWDVELDHERNQVTFGMVLKDGFNGFPGDVRVKAIYCLTDKNELTVDYQA
                     VSDKDTIFNPTNHIYFNLTGDFQRSVAEHRIKIAANHYAPLGEDNLPTGVLEDVTGTP
                     FDFRDFAPFAQGFDSQYPQNVLVKGYDHPWLLEEVDIPVEVLSPDGKIGLSVKTNQPA
                     VVIYTYNFPVEALACYHGVFSLECQALPNACNVDGFGSILLEQGEEFLSKTTYRFTW"
     gene            complement(6233..6634)
                     /locus_tag="AC1PIV_001270"
     CDS             complement(6233..6634)
                     /locus_tag="AC1PIV_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HIP6612293.1"
                     /translation="MVRSLVLVSHGIFCEELKKSTEMIMGPQEDIYTVALLPEEGPED
                     FQKKFEETIAGLEDFVVFADLLGGTPANVVSRKLIEGGQFDLYAGMNMPMVIGFLNGV
                     LLGEAVDYVEFGTSNLVHVNSLLTSDEDDDE"
     gene            complement(6634..7452)
                     /locus_tag="AC1PIV_001271"
     CDS             complement(6634..7452)
                     /locus_tag="AC1PIV_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012774989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HIP6612294.1"
                     /translation="MTKSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKLHTQFFNTSPFFHTIITGIDLALEESDGVASKDAVNGVKT
                     GLMGPFAPIGDSIFGSLVPAIMGTVAATMGKEGSPVGIFLWVAVAIAYDIFRWKQLEV
                     AYKEGTKLITTMRDRLTALVDAASVMGVFMMGALIATMINFEVTWAPAIGEKVIDIQD
                     ILNTIFPRLVPAIFTGFVFWLLGRRGMTSTKAILIIIVLALGFSAIGHFLFGMV"
     gene            complement(7439..8341)
                     /locus_tag="AC1PIV_001272"
     CDS             complement(7439..8341)
                     /locus_tag="AC1PIV_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002922767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HIP6612295.1"
                     /translation="MMQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGN
                     MEVGLLIGASLQLVVLGVGTFGGASRIDATSGAVLATAFSISQGLDPEIAISTIGVPV
                     AGLLVYTDILGRFTTTFFAHRVDAAIERFDYAGIERNYLLGAIPWALSRALPVFLALA
                     FGGGLVETLVTTIELPEYKWIAAGLTLAARMLPGLGFAILLHYLPLKRNLHYLAVGFA
                     LTAMLTVLYGNVSALGGAVAGIVGTLPEDAGVSFVNNFKGLSMIGIAIVGAFLSVIHF
                     KNSQKVTVVAPSNSESGEIEDDEI"
     gene            complement(8380..8865)
                     /locus_tag="AC1PIV_001273"
     CDS             complement(8380..8865)
                     /locus_tag="AC1PIV_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HIP6612296.1"
                     /translation="MAIIATRIDGRLIHGQVANLWTTKLNIGRIMVIDDAVAQNDIEK
                     QGLKLACPPGVKLSILPIEKAANNIKEGKYDSQRLLIVARRPENFLRLVEYGVELAEL
                     NVGNMSQTPETRSVTRSINVVDKDIADFDALAAKGVKLFAQMVPGDSPKDFMPLLDKV
                     R"
     gene            complement(8919..10691)
                     /locus_tag="AC1PIV_001274"
     CDS             complement(8919..10691)
                     /locus_tag="AC1PIV_001274"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004565 - beta-galactosidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 35 protein"
                     /protein_id="HIP6612297.1"
                     /translation="MKEFYIGDQFYLDGEPFKILSGAIHYFRVHPDDWYHSLYNLKAL
                     GFNTVETYVPWNMHEPRKGEFCYEGILDIERFLKLAQELGLYAIVRPSPYICAEWEWG
                     GLPAWLMKEELRVRSSDSVYLQHLDEYYVSLIPKLAKLQLAQGGNVLMFQVENEYGSY
                     GEEKAYLRAVAGLMRKHGLTAPLFTSDGSWRATLRAGTLIEDDVFVTGNFGSKARENF
                     ANMTAFFNEHQKNWPLMCMEFWDGWFNRWGDEIIRREPEEMVDSVMECIELGSLNLYM
                     FHGGTNFGFMNGCSARGQIDLPQVTSYDYDAILDEAGNPTKKFYILQQRLKEVYPELE
                     YAEPLVKEAKAFSDVSLHDKVSLFATLENVSDCVKGFYPKNMEELDQSTGYILYRTEL
                     ERDKTEAERFRVVDARDRIQIYADGKFVATQYQTEIGDDVELDFKDDKLTLDILVENM
                     GRVNYGHKLTAPTQSKGIGRGAMADLHFIGHWETYPLHLESVEDLDFSKGWEEGQAAF
                     YRYQFELDELADTYLDMTGFGKGVVFVNNVNIGRFWEKGPILYLYIPKGYLKKGANEI
                     VVFETEGKYREKIHFSQRPVIKDL"
     gene            10898..11608
                     /locus_tag="AC1PIV_001275"
     CDS             10898..11608
                     /locus_tag="AC1PIV_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HIP6612298.1"
                     /translation="MKVPKYQLIQNDLRQQIVSGKFENGDKFYTESELTKLFNVSSIT
                     VIRAVNELVKDGYLVRQQGKGTFVSRSRKGRLVEFSDIEIFPMDKDKVTVLSCEKGNK
                     PDILEKLNLDKNEFYYKIVRVRAAEDTPYIFHNSYIPQRYIQNPDAPLEHYQSIYQRF
                     KLDYNIHMSEEPFVETNEIVSPCPKEVATHLKLKATEPAVLQNKTTTNSTSGEVMEYT
                     ETYKHWKYYKFEITANHR"
     gene            complement(11748..12479)
                     /locus_tag="AC1PIV_001276"
     CDS             complement(11748..12479)
                     /locus_tag="AC1PIV_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HIP6612299.1"
                     /translation="MVSQTVEKPLYLQLVDELEVAIRERMAPNDKLFSERELTQVYGV
                     SRITVRLALQELEKRGLVYKKHGKGTYVSEISDTAVDLSQAYSFTEQMKKIGKVPRTS
                     ILSFELVKASDYIAQHLQLSQGEEVFEVERLRLADEIPMMLERTYVPASVFPGLAAQR
                     MKSTPLYEIFSEDYHQVIRLAEEEFYASIALDNEAKILGIPSNSPVLHLVRKTYNDKN
                     RIIEFTFSIARADQFRYKITHQRGY"
     gene            complement(12579..12896)
                     /locus_tag="AC1PIV_001277"
     CDS             complement(12579..12896)
                     /locus_tag="AC1PIV_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HIP6612300.1"
                     /translation="MAFEQTNGRYASFGVVTSLPGEVIDSFWYVIDHYLKGVIPLKSV
                     IRFSIKNRRGKITLVFSQEGYKNVLAVDLSSRFDPFYPSTILVMDKQGKETITLPDEV
                     TLL"
     gene            complement(12954..13487)
                     /gene="ntdP"
                     /locus_tag="AC1PIV_001278"
     CDS             complement(12954..13487)
                     /gene="ntdP"
                     /locus_tag="AC1PIV_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017110 - nucleoside diphosphate
                     phosphatase activity [Evidence IEA];
                     GO_function: GO:0017111 - ribonucleoside triphosphate
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside tri-diphosphate phosphatase"
                     /protein_id="HIP6612301.1"
                     /translation="MKLPKEGDFITIQSYKHDGEIHRTWRDTMVLKTTENAIIGVNNH
                     TLVTENDGRRWVTREPAIVYFHKKYWFNIIAMIRENGVSYYCNLASPYVLDNEALKYI
                     DYDLDVKVFADGEKRLLDVDEYERHRKAMKYSDDIDFILKENVKILVDWINNQRGPFS
                     PAYVNIWYKRYLELRSR"
     gene            complement(13563..14339)
                     /gene="recX"
                     /locus_tag="AC1PIV_001279"
     CDS             complement(13563..14339)
                     /gene="recX"
                     /locus_tag="AC1PIV_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HIP6612302.1"
                     /translation="MRITKIEKKKRLYLLEVDGQDSLYITEDTIVRFMLSKGKEITEQ
                     EFRELRDFAQFSYGKNLALYYLSFKQRTKKEVSNYLKKYEIEENNIVKIVTVLEEEKW
                     LDDGNYVDSYVRQNALNGDKGPAMIRQKLMQKGIPKTLIDKRLAEEDFSELAGKIGEK
                     LVGRYQRKLPLRALQDKVVQGLMGKGFSYEAAKQSLGQLELVADEENEDDLIAKELDK
                     QYRKYSRKYEGYELKQRLIQALARKGYDFDRIQAVLRDYL"
     gene            14377..15729
                     /gene="rlmD"
                     /locus_tag="AC1PIV_001280"
     CDS             14377..15729
                     /gene="rlmD"
                     /locus_tag="AC1PIV_001280"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014917211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HIP6612303.1"
                     /translation="MNLQVNQRIPLKIKRMGINGEGIGFYQKTLVFVPGVLKGEEIFC
                     QITSVKRNFVEAKLLKINKESKFRVKPACDIYRACGGCQIMHLRYDKQLDFKQDLLQQ
                     ALKKFKPAGYENYTIYPTIGMDKPSHYRAKLQFQTRSFKDQVKAGLYAENSHRLIGIT
                     NCYVQDAETQEIINGIAKLLTKHRIPIYNERKQHGIRTVMVRKARKTGQVQVIFITSC
                     QVNLIKLIDELTSQFPSIITIALNWNRQKTSDIYGEKTEILWGEQAIDEAVLDYEFSL
                     SPRAFYQLNPQQTEILYGEAVKALDISGDEDLIDAYCGVGTIGFAFAKKVKSVRGMDI
                     IPEAIEDAKANAKRMGLSNTHYEAGKAEEIIPKWYQEGYRADALVVDPPRTGLDEKLL
                     KTILNYKPAKMVYVSCNVSTLARDLVELSKAYKVEYIQSVDMFPHTARTEAVVKLSKK
                     "
     gene            16014..16217
                     /locus_tag="AC1PIV_001281"
                     /pseudo
     CDS             16014..16217
                     /locus_tag="AC1PIV_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002943028.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         4944 a         3800 c         2863 g         4673 t
ORIGIN      
        1 aaaaaggatg tctgagaaag aataaactaa caaaattagt attaaaacca aatttgtcaa
       61 gctaataaaa attaagtcaa aacaacaata atagaaaaac agacaaataa accctataat
      121 aattgtagaa tctagaaata atcgaaagcc attcattgtt ctacttataa taaataagga
      181 aagacaaatt aatataatca tcatataaaa ctcctaatgt attaatttta ttataccaca
      241 aaacccagcc attttaggct gggcatttta tcgtattcta cctacttaac caacttcttc
      301 atctcttcaa tccgcgctac tgtcgcatca tattttgctt ggtagtcggc ttgtttttct
      361 ttttcttttt caacgacttc tggtttagcg ttggcaatga agcgttcgtt gctgagtttt
      421 ttgccgacca tgtctagttc tttttgccac ttgacgagtt ctttgtctag acgagccaac
      481 tcttcttcga cgttaagaag gtctgctagt ggcaagaaga tttcagcacc ggtgataacg
      541 gctgacatgg ctagttctgg tgcagcgatg cttgagctga tttccaactg ctctgggttg
      601 gtaaagcggc ggatgtagtt ttcatttgcc ttgaagaagg tttcaagctc gctatctgcc
      661 gtcttaatca aaatggtaat cggcttagaa ggagcaacat tgacttctgc tctgctattt
      721 cgcaccgaac ggatcaagtc tttaagactt tccactccct tgtgggcttc cgcattttca
      781 aatgctgggt tgacaacagg gtaggccgct accacgatag aaccctctgc gtactgggcg
      841 aaaatctctt ccgtcacaaa cggcatgatt gggtggagga ggcgaaggat ttggtccagc
      901 gtgtagagaa ggacagagcg ggtcatgact ttctcagcct cgttgtcgct gtaaaggacc
      961 tccttggtca gttcgacata ccagttggcg aactcttccc agatgaagtt gtagaggatg
     1021 tgaccagcca caccaaactc gaacttgtca aagttttcag tgactttggc aatggtttcg
     1081 ttgaggttgt ggagaatcca gcggtccgtc acgttgccag cctcgccagc tgcgactttg
     1141 gcaacattct cacgcgccgc atccaaggtc aaaccttcat tgttcatgag gatatagcgg
     1201 gaaatgttcc aaatcttgtt gatgaagttc caagatgcgt ccatcttctc ataagagaag
     1261 cgaacatctt gaccaggggc agagccgttt gacaagaacc aacgcaaagc gtccgcaccg
     1321 tatttctcga taacatccat cgggtcaatc ccgtttccga gcgacttgga catcttgcga
     1381 ccttcttcgt cacggataag tccgtgaatc agagcattct taaatgggct cttgcctgta
     1441 aattcaattc cttggaaaat catacgagac acccagaatg gaataatatc atagcccgtt
     1501 accaaggttg aggttgggaa gtaacgctgg aagtccgccg cgttttcgtc aggccagccc
     1561 atggttgaaa atggccaaag ggcagagctg aaccaggtat ctaggacatc ctcatcctgt
     1621 acccaaccgt cacctgctgg agcctcttct ccgacgtaca tttcgccaga ttcgttatac
     1681 catgctggaa tctgatgacc ccaccaaagc tgacgagaga taacccagtc gtgtacattt
     1741 tccatccatt gtaggaaagt atcgttgaag cgtggtgggt aaaattctac cttgtcagct
     1801 gtatcttggt tggcaatggc attcttggcc aattggtcca tcttaacaaa ccattgagtt
     1861 gacaagcgtg gctcgactac cacacctgta cgctcagagt gtccaacaga atgcacacgg
     1921 ttttcgattt ccacaagggc acccagttct tgcaacttag caaccgttgc cttacgagct
     1981 tcaaagcggt ccatgcctgc aaattcacca gccaactcgt tcatagtacc gtcgtcgttc
     2041 atgacattga cttgtggcag attgtggcgt tgtccaacga ggaagtcatt tggatcgtgc
     2101 gcaggagtga ttttcacaac ccctgtacca aattcaggat ccgcgtgctc atccgcaacg
     2161 attgggattg gcttgttcac aattggaagg ataacatttt taccaatcaa gtccttgtaa
     2221 cgtggatctt ctgggttaac tgcaaccgca acgtcaccga acatggtttc aggacgagtt
     2281 gtggcaactt gaagggcacg agaaccatct tccaacatat aattcatgtg gtagaaagca
     2341 ccctctacgt ccttgtggat aacttcaata tcagaaaggg ctgtgcgagc cgctgggtcc
     2401 cagttgatga taaattcacc acggtagatc cagccttttt tgtagagttc tacaaagacc
     2461 ttgcgaacgg cttttgacaa gccttcgtcc agcgtgaagc ggtcacgttg gtagtccaaa
     2521 gacagaccca acttgcccca ttgttcacga atagtcgctg catactcatc cttccattcc
     2581 cagactttat cgaggaattt ttcgcgcccc aagtcataac gggtcacgcc ttgctcccgc
     2641 aagcgttcct caaccttagc ctgagtagca atccccgcgt ggtccatacc tggaagccag
     2701 agggtatcaa atccctgcat gcgtttttgg cggatgatga tatcttgaag ggttgtatcc
     2761 caagcgtgtc ccaagtgtaa cttaccagtt acgtttggag gtggaatcac gatagaataa
     2821 ggcttagcct ccgcatcgcc tgacggctta aaaacatctt ggtccaacca agtttggtaa
     2881 cgaccagcct caacctcggc tggattgtat tttggtgata attcttttga cattattttt
     2941 tctccttcag tattctttaa aaaaattggt ttatactatc ttcaagctag aaatagccca
     3001 attctttttc atataatctc ctagaaatag tcagtccttt gggctggcta tttcgtttgt
     3061 tcttgctcaa gttcctccat tttttggata attagttgag ctacgtcatt ggcagaaaga
     3121 tgagtattat taattttgag ataatgctga atgccctctg gaatgcctaa cgaggtatat
     3181 cgacatgtat cagctgtaga gagaatctca gcctctgaaa cttcaatgtg tcgtttcaaa
     3241 ggtttatggg taagtcgatt ttctgtccga ttacgccgca aacgttcttc caaagcggtt
     3301 tccaactcaa caaataaaat ttcctggcca tgatgatgaa aaatcgtctg aactgttgta
     3361 aggaattgaa cctctatgag atttttaaaa ttaatcaagg cagttccgat tagtggacgg
     3421 cctgacctag caaacacatc ataaacagca aatgtaatac gtgtattgag gtcaaacata
     3481 tcctcagaaa attcaggaat aaaacgtagg ctaaaatcaa tcgaatcgtg attatgaaaa
     3541 agggtcatcc ctgtcaattt cgcaacttcc tgcccaacgg tcatcttgcc agaagcttgt
     3601 gctccaataa taattagatt cataccccct cccccaccaa ctctatcttt atcccatctg
     3661 gatcttccaa ataaagggca tagtggtctg gtcctcctgc gtggggatag cggtcgtcgt
     3721 agagaagttt gactcgtctg gtcaaaaatt ccttccgcca ttggtcaatc tcatcaggtg
     3781 tccctgcatg aaaagctaga tgattgagac ctgtgcggca acggtggtag cctacctcta
     3841 ggaagtcctc tggcgtttgg acaaagacca ggtattgctc tgctttttta taagacagcc
     3901 ctttatccca ctcctgatag agcgagtagc ccagcttggt caggagaaag tcgtaaaatg
     3961 cacgcgaagt ttccaagtca gaaacgtaaa tttcaacatg atgtaacata tcttctcctt
     4021 tccaaatgaa aatccccgcc tagacttgct agacagggac gaagttattc cgcggtacca
     4081 cccttgttca gatacattat ctgcactttg cttattcgat tcacatcatc agcaaccagt
     4141 tttgacattt gtgcggattt ctcagtacca ccgcttcctg tgacaaatgg ggctcaaaac
     4201 acctctgaat ggctttattg taacaaattg taccttgaaa agcaagggat ttaagctttc
     4261 agctcaatcc ctttttcttt caactgcttg atagttgcag gaccgatgcc tttaagagcc
     4321 aagagctctt tttctgtatg gtttgcaaaa tcagccacag attgaatacc tgcttcgtag
     4381 aaggtttcca aacgtgctgc cgcaatgcct tccaactcag gaagcgccaa aaagtcttcc
     4441 aatgaagtcg ctgaagaagt cacctctgct acaacttctt tcacttgttc cacagtacgc
     4501 tctactacag cctcagcctt gtgagcaact gtctctacta cctctgcagc tctttcaaga
     4561 cctacacgac ctgcacgttt caagtctgct aattgttttt tcaattgttt ttttcgattt
     4621 acttttttct ttgccatgtt aactcctctc cttaataatg cctttgacca aacaactcat
     4681 ctggcaaatc atgaaaacct ttgccagcat ggtagttggc aaatttccct tgaatgaatc
     4741 gataggcatc cagcttgctc tcataacgaa tataagcatc cgctgcacgc tcatccttgt
     4801 cttcttccaa gacacgacga ctttcttcaa ccgccatctc gtttaccatg acctgagtgt
     4861 tgacccaagc ctcaaattct tttaaaaatt cttgttcttt tgtcattatt ttcctctttc
     4921 gcctgcttcg attgaaacac accggtttat tataccatat tttctagaaa acacaagaaa
     4981 accctaactg taacacagtt agagtcccca tttttttacc aagtaaaacg ataggtcgtt
     5041 ttagacaaaa attcttctcc ttgttctaac aaaatcgaac caaatccatc gacattgcat
     5101 gcatttggca aggcctgaca ctctaaacta aagacaccat ggtaacaggc caaagcttca
     5161 acaggaaaat tatatgtata aataacgacc gcaggctggt tggttttgac actgagtcca
     5221 attttcccat ctggactcaa aacttctacc ggaatatcca cctcttccaa taaccatggg
     5281 tggtcatagc cttttaccaa cacattttga ggatattggc tatcaaatcc ctgagcaaaa
     5341 ggcgcaaaat ctctaaaatc aaacggcgtc cctgtcacat cttctaagac acccgttggc
     5401 aggttatcct ccccaagcgg agcatagtga ttggcagcaa ttttaatacg gtgctcggca
     5461 actgaccgtt gaaaatcacc agtcaagttg aaatagatat ggttggtcgg attaaaaatc
     5521 gtatccttat ccgatacagc ctggtagtca actgtcaatt catttttatc cgtcaaacaa
     5581 taaatagcct tgaccctcac atcaccagga aagccattaa aaccatcttt taggaccata
     5641 ccaaaggtca cttgatttct ctcatggtct agctcaacgt cccagtactg ctcatttgcc
     5701 gtgtcaaccc caccgtgtag agtcctacca ggttcatttt ctgtgaaatg gtagcttgtt
     5761 ccctctatct cagcttgggc acctgaaata cgccccgcta ctgggacaat agttgaacca
     5821 gggtacaaat ctgtcttacg gtaatcatca tccgacttgg cagctaaact gacattccgt
     5881 agaccgccat tttcttctac tggcaaaagc acttccacca ctctggcacc aaaatccgtc
     5941 aaggttacct gcatcccatt cttgttttcc aagcaataca gttttgcttt ttcatcaaat
     6001 gtttttactt caatcatttc ttttcctcac aagccaaatg agggagtcac tattgcaact
     6061 tcctcaggat acttaaagcc tatcaactat agaacatttt ataattaacg aaaatcaaat
     6121 ccgtctgtaa caatcagctg agttagcctc actctcttat ttctaggctc gggctgtctt
     6181 tggtcactct ttcatttcaa ggtgaccagt ggaaacagtt tcccaaactg tttcactcat
     6241 cgtcatcttc atcacttgtt aatagactat tgacatgaac taggttgctt gtcccaaatt
     6301 ctacataatc cacagcctct cccagcagga cgccgttcaa gaaaccgata accattggca
     6361 tattcatccc tgcataaagg tcaaactgcc caccttcaat caattttcgt gatacgacgt
     6421 tggctggtgt accgcccaac aagtctgcga agacaacaaa atcttccaat cctgcaattg
     6481 tttcttcaaa ttttttctgg aagtcttctg gaccttcttc tggtaataaa gctactgtgt
     6541 agatgtcctc ttgaggaccc ataatcattt cagtagattt tttcaactcc tcgcagaaga
     6601 taccatgact tactaatact aaacttctaa ccattatacc ataccaaata ggaagtgacc
     6661 gattgctgag aagccaagtg caagcacaat aataatcaag atagctttag tcgaagtcat
     6721 gccacgacga ccaagaagcc agaagacaaa tcctgtaaag attgcaggta ctaggcgtgg
     6781 gaagatggta ttcaaaatgt cttgaatatc aatcactttt tctccaatag ctggagccca
     6841 agtcacttca aagttaatca tagttgcaat caaggcaccc atcatgaaga cacccattac
     6901 agatgctgca tcaacgagag ctgtcaagcg atcgcgcatg gttgtaatca acttagtacc
     6961 ttctttgtag gcaacttcca actgtttcca acggaaaata tcataggcaa tggctactgc
     7021 tacccaaaga aagataccaa ctggagatcc ctctttaccc atagtagcag ccacagtccc
     7081 cataatcgct ggaacaagag aaccaaagat tgagtcaccg attggagcaa atggtcccat
     7141 caaacctgtc ttaacaccgt taaccgcatc tttagaagca acaccatcac tttcttcaag
     7201 tgccaagtca atacctgtga tgatggtatg gaagaatggt gaagtattga agaactgagt
     7261 atgcaatttc atcatttcct tcaactcagg tgtaccatct ccatacattt tacgcaattg
     7321 tggcaaaatc atgtagaggt agccagatgc ctgcatccgc tcatagttcc aaccaagttg
     7381 gaaagtgaac aagctacgtt tgttgatttg attaaaatct tcttttgtta atttgtaatt
     7441 agatttcgtc atcttcaatt tccccacttt ctgaatttga tggagcaacc acagttactt
     7501 tttggctatt tttgaagtga atcactgaaa gaaatgcacc cacaatagcg ataccaatca
     7561 ttgacaaacc tttgaagtta ttgacaaagc ttacgcctgc atcttcagga agagtgccaa
     7621 cgataccagc aactgcacca cccaaagctg atacgttacc gtaaagaaca gtcaacatag
     7681 ctgtaagagc gaaacctacc gccaagtagt gaaggttacg tttaagtgga agatagtgaa
     7741 gtaagattgc aaatccaaga cctggaagca tacgagctgc aagagttaag cctgctgcaa
     7801 tccatttgta ttcaggcaac tcaatcgtag tgacaagagt ttctacaaga ccaccaccaa
     7861 aagcaagggc aagaaaaact ggaagtgcac gagaaagtgc ccaaggaatt gcaccaagaa
     7921 ggtagttgcg ttcaatacca gcatagtcaa aacgttcgat tgctgcatct acacgatgag
     7981 caaagaaagt agtggtgaaa cgacctaaaa tatctgtata aaccaacaat cctgcaactg
     8041 gtacgccaat agtggaaatg gcaatttctg gatctaaacc ttgtgaaatt gagaaagctg
     8101 tcgcaagaac cgcaccagat gttgcatcaa tacgtgacgc accaccgaaa gtaccaactc
     8161 ccaagacaac tagctgcaaa cttgcaccaa ttagcaagcc aacttccatg ttccccatga
     8221 ttaaaccagt gataaaccct gcaaagactg gtgaacctgc tgacgataca attgtcagct
     8281 cgtcacaaat ctggtaagca gagtagagcg ttagaagtaa tatttgccac cattgcataa
     8341 tagtgatcct cctttaaatt tttcaaaaat atccgaatgt tatctaacct tatccaataa
     8401 tggcataaag tcttttggtg aatcgccagg taccatttgt gcaaataatt ttacaccctt
     8461 agccgccaag gcatcaaaat ctgcaatatc cttatctaca acgttaatag aacgagttac
     8521 agaacgagtt tccggagttt gagacatatt ccctacgttc aattctgcca attccactcc
     8581 atattcaact aaacgtagga agttttcagg acgacgggca acaatcaaaa gacgttggct
     8641 atcgtacttc ccttccttaa tgttattagc agccttttcg atcggtaaaa tcgataattt
     8701 tacgcctgga ggacatgcta atttcagtcc ttgtttttca atgtcatttt gagcaacagc
     8761 atcatcgata accatgatac gaccgatgtt caatttcgtc gtccataagt tagcaacctg
     8821 accgtggatc aaacgaccat caatacgcgt agcaataatt gccatacagt gttctccttt
     8881 tcttcataaa tcttttgagc agaaaccgat taaaatttct acaagtcttt tataacgggt
     8941 ctttgtgaaa aatgaatctt ctctctatat tttccttctg tctcgaagac aactatttca
     9001 ttcgctcctt tctttaagta tccttttgga atatagagat agaggattgg tcctttttcc
     9061 caaaaacgtc caatatttac attattaacg aaaacaactc ccttaccaaa acctgtcatg
     9121 tctaagtaag tatccgcaag ttcatccagt tcaaactgat aacgatagaa agcagcttga
     9181 ccttcctccc agcccttact aaaatccagg tcctcaactg actcaagatg caaaggatag
     9241 gtttcccaat gaccaataaa atgtaaatca gccatcgcac ctcgaccaat ccctttagac
     9301 tgggtaggag ccgttagttt gtgcccataa ttgacacgtc ccatattttc taccaaaata
     9361 tctaatgtta gcttgtcatc tttaaaatcc aattcaacat cgtcaccaat ctcagtctga
     9421 tactgagttg caacgaattt tccatctgca taaatttgga tacggtcacg cgcatcaacc
     9481 actcggaaac gttctgcttc tgtcttatcc cgctccaact ctgttctata taaaatataa
     9541 cctgttgact gatcaagttc ttccatattc ttaggataaa acccttttac gcaatcgctt
     9601 acattttcta gagtagcaaa cagactcacc ttatcatgaa gcgacacatc tgaaaaagct
     9661 tttgcctctt ttacaagcgg ttctgcatac tctaattcag gatagacttc tttcaaacgt
     9721 tgttgcaaaa tataaaactt cttagtagga tttccagctt catccaatat agcatcataa
     9781 tcataagaag ttacctgagg caaatcaatt tgaccacgag cagagcaacc attcatgaaa
     9841 ccaaaatttg ttccaccatg gaacatgtac agattcaagg agcccaattc gatacattcc
     9901 ataactgaat caaccatttc ctccggctct ctacgaataa tttcatcgcc ccaacgattg
     9961 aaccaaccat cccaaaattc catacacatg agtggccaat tcttctgatg ttcattaaag
    10021 aatgccgtca tatttgcaaa attctctcta gctttagaac caaagtttcc tgttacaaat
    10081 acatcgtcct ctatcagtgt tcctgcacgt aatgttgctc gccaagaacc gtccgaggta
    10141 aacaagggag cagttagacc atgtttacgc atcaagccag ccaccgctct taaatatgcc
    10201 ttctcctcac cataagatcc atactcattt tccacttgga acataagtac atttccaccc
    10261 tgtgcgagtt ggagcttggc caatttagga ataagagaaa cgtaatattc atctaagtgc
    10321 tgcaagtaca ccgaatcact cgaacgtact ctaagctctt ccttcatcaa ccaagcaggg
    10381 aggccacccc attcccactc agcacaaata tagggggacg gtcgtacaat tgcataaagc
    10441 cctaattctt gagccaattt caaaaatcgc tcaatatcca atataccctc gtaacaaaac
    10501 tcaccctttc gaggctcatg catattccaa gggacatagg tttcaaccgt attaaaacca
    10561 agggccttta agttatacaa agaatggtac caatcatcag gatggacacg aaaataatga
    10621 atcgcgcctg ataaaatctt aaagggttca ccgtccaaat aaaattggtc tccaatataa
    10681 aattctttca tttcttcctc cgatgcaacc gcttaccttt ctattaatat actaacactt
    10741 ctttgtggtt atgtccagta ctttttaaaa atttttttac catttcttat cacctttata
    10801 aagtgaaaaa gtatattttt gtgggtattt tagctatatt ttttgatttt catcaactaa
    10861 tttagtataa taagttgtgg aaaggaagga aataagtatg aaagtaccga agtaccaact
    10921 tatacaaaac gacttacgcc aacagattgt ttctggcaaa tttgaaaatg gcgacaaatt
    10981 ttacacagaa tctgaattaa caaaactatt taatgttagc tccattaccg ttatccgtgc
    11041 agtaaacgaa ctagttaaag atggttacct cgttcgccaa caaggtaaag gaacctttgt
    11101 atctcgttca cgtaaaggac gtcttgtaga attttctgat attgagattt ttccgatgga
    11161 taaggataag gttactgttc tctcgtgcga aaaaggcaat aaacccgata tccttgaaaa
    11221 actaaatctt gacaagaatg agttttacta taaaattgta cgcgtccgcg cagcagaaga
    11281 cactccatac atcttccaca attcatacat ccctcaacga tatatccaga atcccgatgc
    11341 tccactcgag cactatcaat caatctatca acgcttcaaa ctggactaca atatccacat
    11401 gtccgaggaa ccatttgtag aaacgaatga aattgtcagc ccatgtccaa aagaggttgc
    11461 cacccatttg aaattaaaag cgactgaacc agctgtacta caaaacaaaa caactactaa
    11521 cagtactagc ggtgaagtga tggaatatac tgaaacttac aagcactgga agtattacaa
    11581 atttgaaatt acagccaacc atcgctaaaa aaacgcagac taacgtccgc gtttttttca
    11641 tacccaataa caatcaaaag tagcctagga aacgaagccg aagatagaac tggatttcat
    11701 caaggctctt gacaacgaat aattttgatt ttcgaagagt attgattcta atatccccgt
    11761 tgatgggtaa tcttgtaacg aaactggtcc gctctagcaa tactaaacgt aaactcgata
    11821 attctattct tatcattata cgtttttctt accaaatgaa gcactggact attgcttgga
    11881 attccgagta tcttagcttc attatccaaa gcaatacttg catagaactc ttcttctgcc
    11941 aaacgaatca cctgatgata atcctctgaa aaaatttcat acaagggagt tgacttcatt
    12001 cgctgagcag ctaatccagg aaataccgaa gcaggaacat atgtcctttc cagcatcatc
    12061 ggaatctcat cggcaagtct caatcgttca acttcaaaca cttcctcacc ttgactaagt
    12121 tgtaaatgct gcgcaatata gtctgacgcc ttaaccaatt caaaggataa aatagatgtc
    12181 ctcggtactt tcccaatttt tttcatttgc tcagtaaaac tataggcctg agacaaatca
    12241 actgcagtat ctgaaatctc agatacatag gttcccttac catgcttctt atagactaag
    12301 ccccgttttt ccaattcttg caaagccaaa cgaactgtaa tacgactgac accataaacc
    12361 tgtgtcaact cacgctctga aaataacttg tcattcggag ccatcctctc acgaattgca
    12421 acttctaatt catcaaccaa ctgcaaatag agaggttttt caacagtttg actaaccata
    12481 gactcctcct ttctaaccca cataagctta caaatctatt ttacaccaaa tttcatatat
    12541 taacaatatc ttgggtgata aaataccagc tcttcaagct aaagcaaggt tacctcatct
    12601 ggcaaagtaa tggtctcttt tccctgcttg tccattacca agattgttga gggataaaaa
    12661 ggatcaaaac gactacttag atctacagcc agtacatttt tataaccttc ctgcgaaaag
    12721 accagcgtaa tcttaccacg acgatttttg atagaaaaac ggattacact ttttaatgga
    12781 ataacccctt ttaagtagtg atcaataaca taccagaaac tatcaatcac ttccccagga
    12841 agcgaagtca caactccaaa acttgcatag cgcccatttg tttgttcaaa ggccataagc
    12901 ccctccttta caataagaaa aaagcctgta aaacaggatt ttcttttcta actttatcta
    12961 cttctcagtt ctaaatagcg tttgtaccag atattaacgt aggctggaga gaatggtccg
    13021 cgctggttat taatccaatc aaccagtatc ttgacatttt ccttcaaaat aaaatcaata
    13081 tcatccgaat acttcatcgc cttacgatga cgctcatatt catccacatc cagcagtctc
    13141 ttttcaccat cagcaaagac cttaacatct aggtcataat caatgtattt gagtgcctca
    13201 ttgtcgagaa catatggact agcaaggtta caataatagg aaactccgtt ttcacgaatc
    13261 attgcaatga tattgaacca gtatttttta tgaaaataaa cgattgctgg ctctcttgtt
    13321 acccaacgcc taccatcatt ttcagtcact aaggtatgat tattgactcc aataatagca
    13381 ttttccgttg tttttaatac catggtgtca cgccaagtgc gatgaatttc accgtcatgc
    13441 ttataacttt gaattgtaat aaagtcgcct tcctttggta atttcacttt gttaccaact
    13501 ttctacaatt acaatttatc ttgactatta tatcatattt ttctaaccta ggctaaattt
    13561 tttcacagat aatcacgaag gacagcctga atccgatcaa agtcataacc ctttcgagcc
    13621 aaagcctgta tcaacctttg cttcaattca tagccttcat atttacgact atattttcta
    13681 tactgcttat ccaattcctt ggcgattaaa tcatcttcat tttcctcatc agccacaagt
    13741 tccaactgac ccaggctttg tttggccgcc tcataagaaa aacccttacc catcaatccc
    13801 tgtacaactt tatcttgcaa agctcgaaga ggcaattttc tttggtatct acccaccaat
    13861 ttctccccaa tcttcccagc aagctctgaa aaatcttcct cagccagtct tttatcaatc
    13921 agcgttttag gaattccttt ctgcatcaac ttctgacgaa tcatagctgg tcccttatct
    13981 ccatttagag cattctgacg aacatagcta tcaacataat tcccatcgtc cagccatttt
    14041 tcctcttcta ataccgtcac aatcttgaca atattgtttt cttcaatttc atattttttt
    14101 agataattac taacttcttt tttggtacgt tgcttgaagg aaaggtaata aagtgctaga
    14161 tttttcccat aagaaaactg agcaaaatcg cgaagctcac gaaactcctg ctccgtgatt
    14221 tcctttccct tactaagcat gaagcgaaca attgtgtctt ccgtaatata taaactatcc
    14281 tgaccatcca cttcaagtaa ataaagacgt ttcttctttt caatttttgt aattctcatt
    14341 ctttcattat acaggatttt tcggtaaaat aataatatga atctacaagt aaaccaacga
    14401 atccccttaa aaatcaaacg aatgggcatc aacggagaag gcatcggatt ttatcaaaaa
    14461 acgctagtct ttgtccctgg tgtccttaag ggagaagaaa ttttttgtca aattacctca
    14521 gtcaaacgaa atttcgttga agcaaaattg ttaaaaatca acaaggaatc aaaattccgt
    14581 gtcaagccgg cctgtgacat ctatcgagcc tgtggtggtt gtcaaatcat gcacctccgc
    14641 tatgataaac aattagactt caaacaagat ctcttgcagc aggccctaaa aaagttcaaa
    14701 ccagctggct acgaaaacta tactatttat ccaacaatcg gtatggataa gcctagccac
    14761 tatcgtgcca aattacagtt ccagactcga tctttcaaag atcaagtcaa ggccggtctc
    14821 tatgcggaaa attcccatcg cttgattgga attacgaatt gttacgtcca agatgccgaa
    14881 acacaagaga ttatcaacgg aatcgcaaag ctactcacca agcaccgtat tcctatttat
    14941 aatgagcgca agcaacatgg aatccgcacg gtcatggtcc gcaaggctcg aaaaacaggt
    15001 caagttcaag tgatatttat cacctcttgt caggttaatc ttattaaatt aattgatgaa
    15061 ctcaccagtc aatttccaag tataatcact attgctctaa actggaatag acagaaaacg
    15121 agtgatattt atggtgaaaa aacagaaatt ttatggggag aacaagctat cgatgaagct
    15181 gttttagatt acgaattctc actatctcca cgggcatttt accaattaaa tccccaacaa
    15241 acagaaattc tctatggcga ggccgtcaag gctttggata tttcaggaga tgaagacttg
    15301 attgatgcct actgtggcgt gggtacaatc ggcttcgcct ttgctaaaaa ggtcaaatct
    15361 gttcgaggta tggacattat tccagaagcc atcgaggatg ctaaagcaaa cgctaagcga
    15421 atgggactat ccaataccca ctatgaggca ggtaaagcag aagaaatcat tccaaagtgg
    15481 taccaagaag gctacagggc cgatgccttg gtagttgatc ctccacgaac tggactcgac
    15541 gaaaagctcc tcaaaaccat tttgaattac aaaccagcta aaatggttta tgtatcctgc
    15601 aacgtctcca ctcttgcaag ggaccttgtt gagctaagca aagcctacaa ggtagaatac
    15661 attcaatctg ttgacatgtt tccccacaca gcacggaccg aggcggttgt taaactaagc
    15721 aaaaaataaa aggcactata agactatgac gggtaaaccc actatggtca tatagagcct
    15781 ttttgagtgt agaaaaaagt cccctacgac ctatactgat acccatttaa aatcaaaaat
    15841 agccacctac cacttaaagt agatatggag cattttgatt ttgttatttt ttgagaaaaa
    15901 aacagctact tgaaatccac aatcctcaac tcaaacttat aaattaaggt tttacatgtt
    15961 ataagtaaat tagacttgct atttttgatt tttattgagt atgaaaaaca acaaaactca
    16021 caatttccaa caccaaatca gaaacaacta acaatctcat caaagtcatt aaaagaaatg
    16081 cctttggatt caggaaaatg gaaactagaa aaacggattt tgatgctttg aacagtgaaa
    16141 agctgaggag agctcttttc agctcatctc ctaaaaacaa gaaagagaga acgaatttcg
    16201 tcctctctag gtgttagctt ttcatctacc cactacagtt gacaaagagc caaaaaaaaa
    16261 gaacattgct gctctcttac
//
LOCUS       DBNFCO010000046        16238 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.046, whole genome shotgun sequence.
ACCESSION   DBNFCO010000046 DBNFCO010000000
VERSION     DBNFCO010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 16238)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16238)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16238
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.046"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            4..645
                     /locus_tag="AC1PIV_001282"
     CDS             4..645
                     /locus_tag="AC1PIV_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HIP6612304.1"
                     /translation="MKKEISPEMYNYNKYPGPSFARVGDKVVSENIELDLLEDYKNAF
                     DQTIFGQRFSQLMLKFDYIVGDWGNEQLRLRGFYTDDKNVKSDLKISRLDDYLTEYCN
                     FGCAYFVLANPNPQDLPAEEENRPRRKRSRSRNRNRNQPRTEPIAPKENKSNRNDRQK
                     KGKQQNKQSEQRHFTMKNAGVKASQTERSQKRERKQSKREMNEVKRNFVIRQK"
     gene            654..1766
                     /gene="rlmN"
                     /locus_tag="AC1PIV_001283"
     CDS             654..1766
                     /gene="rlmN"
                     /locus_tag="AC1PIV_001283"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HIP6612305.1"
                     /translation="MKPSIYAFSQANLVDWILENGEKKFRATQIWEWLYRSRVQSFAE
                     MTNLPKSLIEKLEEHFVVNPLKQRIVQESKDGTIKYLFELPDGMLIETVLMHQHYGLS
                     VCVTTQVGCNIGCTFCASGLIPKQRDLTSGEIVAQIMLVQKYLDERNQNERVSHIVVM
                     GIGEPLDNYDNVMTFLRVVNDDKGLAIGARHITVSTSGLAPKIREFAREGVQVNLAVS
                     LHAPNNDLRSSIMRINRKFPIEVLFEAIEDYIKVTNRRVTFEYIMLNEVNDGVEQAQE
                     LADLTKNIRKLSYINLIPYNPVSEHDQYSRSTKERTLAFFDVLKKNGVNCVVRQEHGT
                     DIDAACGQLRSNTLKKDREKARARIAAAKAKAGIRA"
     gene            1763..2290
                     /locus_tag="AC1PIV_001284"
     CDS             1763..2290
                     /locus_tag="AC1PIV_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HIP6612306.1"
                     /translation="MRKFFQADGNLTKLGRQICKTLAGAYALAIVLLCFLPQTWYPQY
                     KDFSTPGIIQIGRLYLLPTPFNSIVNGDKVDSLADLGWIFLQNITNIFLLFPLIFLLL
                     FLREEWRSLRAVIRYSFCISLFIECTQLLLDLLIDAQRVFEIDDLWTNTMGGILAYFS
                     YSLIKRGIILSKQES"
     gene            complement(3586..4410)
                     /gene="nadE"
                     /locus_tag="AC1PIV_001285"
     CDS             complement(3586..4410)
                     /gene="nadE"
                     /locus_tag="AC1PIV_001285"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003952 - NAD+ synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0008795 - NAD+ synthase activity [Evidence
                     IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HIP6612307.1"
                     /translation="MTLQETIIKELGVKPSIDPKEEIRRSIDFLKDYLKKHPFLKTYV
                     LGISGGQDSTLAGRLAQLTMEEMRAETGDDSYQFIAIRLPYGVQADESDAQAALAFIQ
                     PDVSLTINIKESTDAMVAAVNANGLAMSDFNKGNAKARMRMIAQYAIAGERKGAVIGT
                     DHAAENITGFFTKHGDGGADILPLFRLNKRQGKQLLAALGADEKLYLKVPTADLEEDK
                     PGLADEVALGVTYNQIDDYLEGKTIDPQSQTIIEGWWNKTAHKRHLPITIFDDFWK"
     gene            complement(4423..5883)
                     /locus_tag="AC1PIV_001286"
     CDS             complement(4423..5883)
                     /locus_tag="AC1PIV_001286"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004516 - nicotinate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HIP6612308.1"
                     /translation="MTLFKDDSLTLHTDLYQINMMQVYFDQNIHNKHAVFEVYFRSQP
                     FKNGYAVFAGLERVVNYLNNLSFSQTDIDYLTELGYPKDFLDYLSQLEMTLTVRSAKE
                     GDLVYANEPILQIEGPLAQCQLIETALLNIVNYQTLIATKARRIKAVIEDEPLMEFGT
                     RRAQEMDAAIWGTRAAFIGGASATSNVRAGKIFGIPVAGTHAHALVQTYGDDYKAFKA
                     YAETHHDCVFLVDTYDTLRIGVPAAIKVAKEMGDKINFKGVRIDSGDMAYISKKVRQQ
                     LDDAGFTDAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVS
                     IEDEDGNMRDTIKLSSNAEKVSTPGKKQVWRITSKEKGKSEGDYITFADTDVTQMDNI
                     YMFHPTYTYINKTIENFDARPLLVPIFEKGKQVYELPSLAEIQTYANQEFDKLWDEYK
                     RVLNPQLYPVDLAQDVWDNKMNLINRIRKQTQTKSI"
     gene            complement(5991..6635)
                     /locus_tag="AC1PIV_001287"
     CDS             complement(5991..6635)
                     /locus_tag="AC1PIV_001287"
                     /EC_number="3.4.23.43"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014917297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HIP6612309.1"
                     /translation="MKTIILFFLGASIGSFLGLVIDRFPEQSIIAPSSHCNACKRRLK
                     AWDLIPVLSQLSTKSKCRYCKAKIPYWYLGLEFLAGLVVLLCHFQVLNLTETILILAG
                     LVLTIYDIKHQEYPFAVWLIFTFIALILSQLNWLFCGFLLLAYLTEKWQINIGSGDFL
                     YLASLALICGFTELLWIIQISSLLGLLVFAIFKPKSIPYVPLLFLSSIPIILCT"
     gene            6757..7311
                     /locus_tag="AC1PIV_001288"
     CDS             6757..7311
                     /locus_tag="AC1PIV_001288"
                     /EC_number="2.1.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004808 - tRNA
                     (5-methylaminomethyl-2-thiouridylate)(34)-
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (mnm(5)s(2)U34)-methyltransferase"
                     /protein_id="HIP6612310.1"
                     /translation="MLRPLHMAHAFLDEILTDQDLAVDATMGNGHDTLFLAQRAGKVV
                     AFDIQEQALTTTAEKLEKAGLTNAQLVLTGHENLDQYVDECKAAIFNLGYLPSADKSV
                     ITLPATTLQAIEKVLNRLVVGGRLAIMIYYGHEGGALEKDAVLDFISQLDQTVFTAML
                     YKPLNQVNTPPFLVMVERLKSSSN"
     gene            complement(7327..8106)
                     /locus_tag="AC1PIV_001289"
     CDS             complement(7327..8106)
                     /locus_tag="AC1PIV_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIP6612311.1"
                     /translation="MIISMKNVHYKRQGKTILEDINWEFRKGERWAILGLNGAGKSTL
                     LRILMAEFWKTSGDLTVLGVEFGKGDIPSLRTKIGVVGSFLAERFPIDLTAEQIVLTG
                     KYKSSILYREYGQAELDEAIDMLKTIKAEHLIGRAYASLSQGERQLLLIARSLMEEPA
                     ILILDEATVGLDLLARERLLHHIDYLCQLPTAPAIIYVTHHAEEITDNFTHVLLLKDG
                     MVLAQGPKEDILTPELLSDFYGNQVELIDLGEGRLFIKPIL"
     gene            8239..9576
                     /locus_tag="AC1PIV_001290"
     CDS             8239..9576
                     /locus_tag="AC1PIV_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HIP6612312.1"
                     /translation="MEDPGSQTIYLQLLILFLLTLFNAFFSASEMALVSLNRSRVEQK
                     AADGERKYIRLLQVLENPNNFLSTIQVGITFISILSGASLANDLGAVFAKWMGNSTTA
                     QTAGYWLALAMLTFVSIVLGELYPKRIAMNMKENLAVVTAPVIIFLGKIVSPFVWLLS
                     AATNLISRITPMNFDDADEQMTRDEIEYILTKSEKTLDAEEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIEDDTATIMAAILKQNFSRIPVYDGDKDNIIGLIHTKKILSEAFSN
                     GFDNLNIRRIMQEPLFVPETIFVDDLLTSLRNTQNQMAILLDEYGGVAGLVTLEDLLE
                     EIVGEIDDETDKTEIFVREIADNTYIVQGNMTLNDFNEHFEMELESDNVDTIAGYYLT
                     GVGTIPSQDEKVSFEVDSKDHHLVLINDKVKNGRVTKLKLLITPLEKEETDKD"
     gene            9697..10488
                     /gene="pflA"
                     /locus_tag="AC1PIV_001291"
     CDS             9697..10488
                     /gene="pflA"
                     /locus_tag="AC1PIV_001291"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate-lyase-activating protein"
                     /protein_id="HIP6612313.1"
                     /translation="MMTEIDYRKVTGLVHSTESFGSVDGPGVRFVVFMQGCHMRCQYC
                     HNPDTWDLVNPAATERTAEDVLNEALRFRMFWGKEGGITVSGGEATIQIDFLIALFTL
                     AKEKGIHTTLDTCALTFRKTERYLEKYSRLMEVTDLVLLDIKEMNPEQHRIVTGHSNK
                     TILECAQYLSDIGKPVWIRHVLVPNLTDRDEDLIELGKFVKTLKNVERFEVLPYHNLG
                     EFKWRELGRPYPLEGTKPPTKARVENAKALMETETYQEYLNRIKG"
     gene            complement(10598..12295)
                     /locus_tag="AC1PIV_001292"
     CDS             complement(10598..12295)
                     /locus_tag="AC1PIV_001292"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HIP6612314.1"
                     /translation="MKFSDYTYVRPDYEAIKAQFTDLTDQLAQASDLETTRTLVAAVT
                     KLLNLVDTQYNLWMIRHTIDMNDEFYNEETKFWNEYSPLFEELTTNYYRIIVQTPYKE
                     ELSDILPQTFFMQAENKLKTFSSDVIPLLQKENELTDEYSKLIAGAEIDFQGQTYNLS
                     QMGPFGQSTDREVRKAASAATTTFFESKEADFDRVYDELVKVRTEIAHKLGFKDYVEY
                     GYLKMNRFDYNRDMVKVYREEILKHIVPIVQNLRQRQANRLQVPSLKHYDLNLEFLDG
                     NAVPQGDPDFIVSQAQDMYRELSAETGEFFDFMIEHELLDLVAKPGKNSGGYCTYIPD
                     FKSPFIFSNFNGTSGDIDVLTHEAGHAFQVYRSRWIQSPEVVWPTYETCEIHSMSMEF
                     MTWPWMDRFFKEQVDKYKFTHLASALLFLPYGVLVDHFQHEVYERPEMTPAERKATWK
                     KLQDLYLPDRDYSESEALNRGIFWYRQGHIFASPFYYIDYTLAQVCALQFWKRTQVDH
                     DENAWEDYIRICDLGGTKSFLQVVEAANLQSPFKEGALESTAKAAADWLNTVKDSDL"
     gene            12434..13369
                     /locus_tag="AC1PIV_001293"
     CDS             12434..13369
                     /locus_tag="AC1PIV_001293"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004427 - inorganic diphosphate
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HIP6612315.1"
                     /translation="MSKFLVFGHQNPDTDAIASSYGWAHLEREVFGRDAEAVVLGTPN
                     EETAFALDYFGVTAPRVVESAKAEGVSQVILTDHNEFQQSIADIKEVEVAAVIDHHRV
                     ANFETANPLYMRLEPVGSASSIVYRAFKENGVIPPKEVAGLLLSGLISDTLLLKSPTT
                     HVTDPQVAAELAEIAGVNLEEYGLALLKAGTNLASKSAEELIDIDAKTFGLNGNDVRV
                     AQVNTVDIAEVLERQAEIEAAMTAASVANGYSDFVLMITDIVNSNSEILALGSNMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTDAFNA"
     gene            13930..16108
                     /gene="yzpA"
                     /locus_tag="AC1PIV_001294"
                     /pseudo
     CDS             13930..16108
                     /gene="yzpA"
                     /locus_tag="AC1PIV_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027584.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK domain-containing zinc-binding protein
                     YzpA"
BASE COUNT         4782 a         3043 c         3711 g         4702 t
ORIGIN      
        1 caaatgaaaa aagaaatttc acctgaaatg tataactata ataaataccc tggtccgagt
       61 tttgctcgtg tcggagataa ggttgtatct gaaaatattg aattggacct tttggaagat
      121 tacaagaatg cttttgatca gacgattttt ggtcaacgtt tttcacaact catgctcaaa
      181 tttgattata ttgtgggaga ttggggcaat gagcagctga gattaagggg attctataca
      241 gacgataaaa atgttaaatc agacttaaaa atcagccgct tagacgacta tttgacggag
      301 tattgtaatt ttggttgtgc ttatttcgtc ttagccaatc cgaatccaca agacttgcct
      361 gctgaggagg agaatagacc gcgtcggaag cggagtcgtt ctcgcaatcg gaacagaaat
      421 cagccgcgga cggagcctat tgcgccaaaa gaaaacaaaa gtaatcgcaa tgaccgtcag
      481 aaaaagggga agcagcaaaa caaacagtcg gaacagcgtc attttactat gaagaatgct
      541 ggtgttaagg cgagtcaaac ggagcgttct caaaaacgtg agcgtaaaca aagcaagcgt
      601 gagatgaatg aagtgaagcg taactttgtt atccgccaga aatagggaga aatatgaaac
      661 catcaattta tgcatttagt caagccaatc tggttgattg gattttagaa aacggagaga
      721 agaagttccg tgccactcaa atttgggaat ggctctaccg ttctcgtgtc caatcttttg
      781 cggaaatgac caacttgcca aaatctttga ttgaaaagtt ggaagaacat tttgtagtta
      841 atccgctcaa acaacggatt gtacaggagt ctaaggacgg tactatcaaa tacctttttg
      901 aactgccaga tggcatgttg attgagacag ttctcatgca ccagcactat ggcctttctg
      961 tttgtgtaac gacacaagtt ggctgtaata tcggctgtac attctgtgca tctggattga
     1021 ttcctaagca acgtgacttg actagcggtg agattgtggc tcagattatg ttggtacaaa
     1081 agtacttgga tgagcgcaat cagaatgagc gtgttagcca tatcgttgtg atggggattg
     1141 gtgagccgct tgataactac gataatgtta tgaccttctt gcgagtggtt aatgacgaca
     1201 agggcttggc aattggtgcc cgtcacatca ctgtttctac gtcaggttta gcaccgaaaa
     1261 ttcgagagtt tgcacgtgaa ggtgtccaag taaacttggc agtatctcta catgcgccaa
     1321 ataatgacct tcgttcgagc attatgcgca ttaatcgcaa attccctata gaagttcttt
     1381 ttgaagcaat cgaagactat atcaaagtga ccaaccgccg tgtgactttt gagtatatta
     1441 tgctcaatga ggtcaacgat ggagtggaac aggcacagga attggctgac ttgactaaga
     1501 atatccgtaa attgtcttat atcaacttga ttccttataa cccagttagt gaacatgacc
     1561 agtacagtcg ttcaaccaag gaacgtactc ttgctttctt tgatgttttg aagaaaaatg
     1621 gtgttaactg tgtcgttcgt caggaacatg gtacagatat tgatgctgcc tgtggtcaat
     1681 tgcgctccaa tacgctcaag aaagaccgtg aaaaagcccg tgctcgtatt gcagccgcaa
     1741 aagcaaaggc aggtattcga gcatgagaaa attcttccaa gcagatggga acctgaccaa
     1801 gctgggaaga cagatttgta agaccttagc tggagcctat gctctggcta ttgttttact
     1861 ttgtttccta ccacagactt ggtacccaca gtataaggat ttctcgaccc caggaattat
     1921 tcaaattggc cgtctctatc ttttaccaac tcctttcaac agcatcgtca acggggacaa
     1981 ggtagatagt ttggcggacc tagggtggat tttcttgcaa aacatcacta acatttttct
     2041 acttttccct ctgatttttc ttcttttgtt tcttagggaa gaatggcgga gccttcgagc
     2101 ggtgattcgt tatagttttt gtatcagtct ttttattgaa tgcacacaat tactactgga
     2161 tttgctgatt gatgcccaac gcgtctttga aatcgatgat ttatggacca atacaatggg
     2221 gggaatacta gcctatttta gctattcatt gataaagaga gggataatcc tttccaaaca
     2281 ggagtcttag aacctaccgt cacaggttca gaatgtccat ctaatgctat tgtttaagct
     2341 acatatcgtt atttttttga aatacagtca gtattccctt aaaaatgacc ttgactagct
     2401 aaagctatct ttgatatggg agtgggaaag acatttaggt tcggcttcta tggtcacttt
     2461 ctagttttaa ggtgaccagc tgaaacagtt cctcaaattg tttcactccc acctccgcat
     2521 agctccgaag gttcggggaa cctttggagg ctggagatat agcgaacaaa gttcgcatca
     2581 gtcgtagagg tcagatttgg agtgtaaaac atgaattgct gagatttgct tcgcaaatct
     2641 tatctccaac ctttaacctc gcttttccct ttctaggatc gggctgaaac agttccccga
     2701 actgtttcac tccactggac tgttaaaccc aatcaaccac tgcgctgaga tggtgacact
     2761 aactttgaga agcggtgctg ggcttgagcc cagcctcgtg agtacagttt tttagaaagt
     2821 cacttaagca gagtggcttt ttgttagttt ttaatggatt caggcaatgg aaactgaatt
     2881 ttcaaattgt ttagaaaatt tctaaaaatc acttgaccat tttgattttg taacgtataa
     2941 ttacaagtaa tcagaaaatg taataaacac tttgtcttta gagagtctat ggttggtgtg
     3001 aatagatgat agaggtttat gagataggct gatgccaaac aagcattcgt atccatttta
     3061 tggattgtct ggtttagtaa agtgagtttg gttcgatgaa ttcgaaacaa tgagagttcg
     3121 gtccgcaccc cttatcgtgc gcctccttgt tagaggagaa aaagttatgg acttttctag
     3181 tcgagtccat agtgaggtgg caccgtgtcc attgacgccc acgcaggata ttttttcctg
     3241 cgtgggcttt tttcattatg gtttgaagtt ataataaaaa acaaaacccc tgacggttca
     3301 actgtcaggg ctccattttt tattattcga tgaaaatcaa aagtagccta gcttcaacta
     3361 tctgggagat agttgaaggt tggaaatata gcgaacatgt ttcgcatcaa aactatctgg
     3421 gagatagttg aagctaggaa atatagcgaa cattgtttgc gccttcaagt tgatgttaga
     3481 actctgttcc ttttatattt caagggaaca ggctgaaaac ctccacagga gcttttcagt
     3541 catcaaatca agtcaataac gtctgatttt gattttcgag gagtattatt tccaaaaatc
     3601 atcaaaaata gtaattggca ggtggcgttt atgggctgtt ttgttccacc atccttcgat
     3661 aatggtttgg gattgagggt cgatggtttt accttcgaga tagtcgtcga tttggttata
     3721 ggtaacacca agtgcgactt cgtcagcaag gcctggtttg tcttcttcca agtctgcagt
     3781 aggaactttg aggtagagtt tttcatctgc tcccaaagca gctagaagtt gcttaccttg
     3841 acgcttgtta aggcggaaga ggggcaggat atctgcacct ccatcaccgt gcttggtaaa
     3901 gaaaccagtg atattttcag cggcatgatc ggttccaata acagccccct tgcgttctcc
     3961 agcgatagcg tattgggcaa tcatgcgcat gcgggcttta gcatttccct tattaaaatc
     4021 agacatagca agcccatttg cattgactgc agccaccatg gcatctgttg attccttgat
     4081 gttgatggtt aagctgacat ctggttgaat aaaggctagg gctgcttggg cgtcagactc
     4141 atcagcttgc acaccgtaag gcaggcggat agcgataaat tgataagaat cgtcacctgt
     4201 ttccgcccgc atttcttcca tagtcagctg ggccaaacga ccagccaagg tcgaatcttg
     4261 tccaccagaa atccccaaga cgtaggtttt caaaaatggg tgttttttca gatagtcttt
     4321 gagaaagtcg atggagcgac ggatttcttc tttggggtca atgcttggct tgacgcctaa
     4381 ttctttgatg attgtttcct gtagggtcat aacatacctt tcttagatgg atttggtctg
     4441 agtttgtttg cgaatacgat tgatgaggtt catcttatta tcccaaacat cttgtgccaa
     4501 gtcgactgga tagagctgtg ggttgagcac gcgtttgtat tcatcccaga gtttatcaaa
     4561 ttcttgattg gcataggttt gaatttccgc taggcttgga agttcataga cctgttttcc
     4621 tttttcgaaa ataggaacta ggagaggacg ggcatcaaag ttctcgatgg ttttattgat
     4681 ataggtgtaa gttggatgga acatatagat attatccatc tgtgtgacgt cagtgtccgc
     4741 aaaggtgatg tagtcccctt ctgattttcc tttttctttg gaggtgatgc gccaaacctg
     4801 tttcttacca ggagtggaga ctttttccgc attagaagac agcttgatgg tgtcacgcat
     4861 atttccatct tcatcttcga tggatacaat cttgtagaca gcgcccagag ctggttggtc
     4921 gtaggcggtg atgagtttgg taccaactcc ccagacatca atttttgcct tttgcatttt
     4981 gaggttgagg atggtatttt catcgaggtc attagatgcg taaatcttcg catctgtaaa
     5041 acctgcatca tctaattgct gacgaacttt cttagaaata taggccatat cgcctgaatc
     5101 aatccgaacc cctttgaagt taatcttatc tcccatttct ttggcaacct tgatggctgc
     5161 tggaacacca atacgaagcg tatcataggt atcaacgagg aagacacagt catgatgggt
     5221 ttcagcgtag gctttgaaag ccttgtaatc atctccgtat gtttgaacca aggcgtgggc
     5281 atgggtacca gcgacaggga tgccgaagat tttgccagct cgaacattgg aagtcgcaga
     5341 tgctccacca ataaaggctg cccgtgtacc ccagatagca gcatccattt cttgggcacg
     5401 gcgagtgcca aattccatca agggctcatc ttcaatgaca gccttgatac ggcgagcttt
     5461 tgtggcaatt agggtttggt agttgacaat gtttaagagg gcagtttcga ttagttggca
     5521 ttgtgccaat ggtccttcga tttgcagaat gggttcgtta gcgtagacca ggtcgccctc
     5581 cttagccgaa cggacagtga gagtcatttc caattgggac aagtaatcaa ggaaatcctt
     5641 cggataacct agttctgtca gatagtcaat gtctgtctgg ctaaagctga gattgttgag
     5701 gtagtttaca acgcgttcca aaccggcaaa tacagcgtag ccatttttaa aaggttgtga
     5761 acggaaatag acttcgaata cagcgtgttt attgtggatg ttttggtcaa aatagacctg
     5821 catcatgttg atttgataaa ggtcggtatg cagggttaaa ctgtcatcct taaatagtgt
     5881 cataacgttt ctccttttgc cttcctatca agaaggtgct ccaattattt tgatggagtt
     5941 gaactctaat atgccttcta ttataacaaa aaaatcgaga aaaactcgat ttaggtgcac
     6001 agaatgatag gaatacttga aagaaatagg agtggtacgt agggaataga cttgggtttg
     6061 aaaatggcga agacaagaag ccctaggagg gaactaatct ggataatcca gaggagttct
     6121 gtaaatccac atattaaggc caaacttgcc agatagagaa agtcaccaga accaatattg
     6181 atttgccatt tttcagtcag ataggccaag agtaaaaagc cacagaaaag ccagttgagc
     6241 tgggagagta tcagagctat aaaagtaaaa atgagccaga cagcaaaagg atattcctga
     6301 tgcttgatgt cgtaaatggt caaaactagt cctgccaaga tgagaatggt ttcggttagg
     6361 tttaggactt gaaaatggca gagcaggaca actagaccgg ctaagaattc caatcccaga
     6421 taccaataag gtatcttcgc cttgcagtaa cggcatttgg attttgtcga aagctgggat
     6481 aggactggaa ttaagtccca ggccttgagc cgtcgtttgc aggcattgca gtgactagag
     6541 ggggcgataa tggactgttc agggaaacgg tcgatgacca atcccaagaa ggagccgata
     6601 gaagctccaa ggaaaaatag gataattgtc ttcataccta tttattcgca aaaggaatag
     6661 gaaaaatgga agatttttaa aaaatttttt gaagatggaa agtatgctat actagatgtg
     6721 atagatttta tgtattgacg ataattagga gaaagtatgc ttagaccttt acacatggcc
     6781 catgcctttt tagatgaaat attaacagac caggacctag cggtcgatgc gactatggga
     6841 aatggccatg acacgctatt tttagcccaa cgagcaggaa aagttgtggc ctttgatatt
     6901 caggaacaag ccctgactac aacggctgaa aaactagaaa aagctggctt gaccaatgcc
     6961 caattggttt tgacaggaca cgaaaaccta gaccagtatg tggatgaatg caaggcagcg
     7021 attttcaatc tgggttatct accttcggcg gacaagtcag tcattaccct gcctgcaacc
     7081 acccttcaag ccattgagaa agtcctgaat agattggtgg ttggaggtcg cttggctatc
     7141 atgatttact atggtcacga gggtggagct cttgagaagg atgcagtttt agactttatc
     7201 agccagcttg accaaaccgt ctttacagcc atgctctaca aaccgctcaa ccaagttaat
     7261 accccaccat ttttggtcat ggtggaacga ttaaaatcca gctcgaacta gagctggatt
     7321 tgttttttat aatatcggct taatgaacaa tcttccctca cccaagtcaa tcaattccac
     7381 ctgatttcca taaaaatcgc tgaggagttc aggtgtcagg atatcttctt tgggtccctg
     7441 tgccaagacc atgccatctt tgagcaggag gacatgggtg aaattatcag tgatttcctc
     7501 ggcgtgatgg gtgacgtaga taatggcagg agccgttggg agttgacaga ggtagtcaat
     7561 gtggtggagc aggcgctcgc gagctaggag gtccaaaccg acagttgctt cgtctaaaat
     7621 caaaatagcc ggctcttcca tcaaacttcg ggcaatcagc aggagttggc gttctccttg
     7681 tgacaaacta gcataggccc gaccgatcaa gtgctcagcc ttaatggttt tgagcatgtc
     7741 tatggcttca tccaattcag cttgaccgta ttcacgatag aggatggagg atttatattt
     7801 tcctgtcaag acaatctgct cagccgtcaa atcgattgga aaacgctctg ccaaaaagga
     7861 gccaactacc ccaatcttgg tgcgtagact aggaatatct cccttaccaa attccacccc
     7921 cagaacagtc aggtcaccag aggtcttcca aaactcagcc attaaaatac gaaggagggt
     7981 tgactttcca gccccattga gccctaaaat agcccaacgc tctccttttc taaattccca
     8041 gttgatgtct tctaaaatag ttttaccttg tcgtttatag tggacattct tcatcgaaat
     8101 aatcatagtt gctctcctat tccttttgat tattgtaaca taaacagata tgagggacta
     8161 attataacaa gaaatatgtt aatttttaga atttgtggta taatggaaat gttataaatt
     8221 ttattatagg agaacatcat ggaagaccct ggtagtcaga ccatctattt acaactgtta
     8281 attttattct tattgactct gttcaatgcc ttcttttcag cctcagaaat ggcccttgta
     8341 tccctcaatc gttcaagagt agaacaaaag gcagcagacg gtgagaggaa atatattcgc
     8401 ttgcttcaag ttttagagaa tcctaacaat tttctatcaa ccattcaggt cggtattacc
     8461 ttcatctcca tcctttcagg tgccagcttg gctaatgatt taggagctgt atttgccaaa
     8521 tggatgggga attcaacaac agctcaaact gctggttact ggcttgcact ggctatgttg
     8581 accttcgttt caatcgttct tggcgaattg tatcctaagc ggattgccat gaatatgaag
     8641 gaaaatctgg cagtagtcac tgcaccagtg attattttcc ttggaaaaat tgttagtccg
     8701 ttcgtgtggt tattatcagc tgcaacgaat cttatcagcc gtattactcc tatgaatttt
     8761 gatgatgcgg atgagcaaat gacacgggat gaaattgaat atattttgac aaagagtgag
     8821 aaaaccttag atgccgaaga aatcgaaatg cttcaaggtg tgttctcttt agatgagctg
     8881 atggcacgtg aagtaatggt tccccgtacg gatgctttca tggtggatat tgaggatgat
     8941 acagcaacca tcatggcagc tatcctcaag cagaattttt cacgtatccc tgtttatgat
     9001 ggcgataagg acaatatcat tggtctgatt cataccaaga aaatcttgtc agaagctttc
     9061 agtaatggct ttgacaatct caacatccgc cgcattatgc aggagcctct cttcgttcca
     9121 gaaacgattt tcgtggatga tttgttgaca tcattgagaa atacccaaaa tcaaatggcc
     9181 atcttgttag atgagtatgg tggagttgca ggtctcgtta ccttggaaga tttgctggaa
     9241 gaaattgttg gggaaatcga tgatgagacc gataagacag aaatttttgt tcgagaaatt
     9301 gctgacaaca cctatatcgt ccaaggaaat atgaccttga atgacttcaa tgagcatttt
     9361 gagatggagt tggaaagtga taacgttgat acgattgctg gttattatct gacaggagtc
     9421 ggtaccattc cgagccaaga tgagaaagtt tcctttgaag tagatagtaa agatcaccac
     9481 ctagttctta ttaacgataa ggtaaaaaat ggtcgcgtaa caaaattaaa actcttgatt
     9541 acaccactgg agaaagaaga aaccgataag gactagggca acctagtctt ttagcttttt
     9601 tcttgcggaa gatgatggtt atgaaagaaa gaaagtaaat gatagaagcg ttttcatttt
     9661 tgtgatatac tagtcttata aaatgatgag gatgagatga tgacagaaat tgattatcgt
     9721 aaagtgacag gtttggttca ttcaacagag agttttggtt cggttgatgg cccaggggta
     9781 cgttttgtag tctttatgca gggctgtcac atgcgttgcc agtattgcca taacccagat
     9841 acttgggatc tggtcaatcc agcagcgact gagagaacgg cggaagatgt cttgaatgaa
     9901 gctctgcgtt ttcgtatgtt ttggggaaaa gaagggggga ttaccgtttc aggtggtgaa
     9961 gcaaccatcc agattgattt tttaattgct ctgtttaccc ttgcaaaaga aaaagggatt
    10021 cacactactt tggatacctg tgcgttgact ttccgtaaga cagagcgtta cttggaaaaa
    10081 tatagtcggc ttatggaagt aacagatttg gtgctccttg atattaagga aatgaatcct
    10141 gagcaacacc gcattgtgac aggtcacagt aacaagacta ttttagaatg tgctcaatat
    10201 ctatcagaca ttggtaagcc tgtttggatt cgtcatgtcc tggtaccaaa tttgactgac
    10261 cgagatgagg acttgattga acttggtaag tttgttaaaa ccttaaaaaa tgtcgaacgt
    10321 tttgaggtgc taccttatca caatcttggt gaatttaagt ggcgtgagtt gggcagaccc
    10381 tatccactag aggggaccaa gcccccaacg aaggctcgag tggaaaatgc aaaggccttg
    10441 atggagacag agacctatca ggagtacttg aatagaatta agggataata gtgaagaggt
    10501 cggagattga tgcgaaaaag atttaatgtg ttagggacaa gtatcatata atcaaaaaat
    10561 ctgaatgagt catttgattc attcagattt ttgtgtttta taagtcgcta tccttaactg
    10621 tatttaacca atcagcagca gctttagctg tgctttcaag ggcaccttct ttgaacggtg
    10681 attggaggtt tgcggcttca accacttgca agaaggactt ggtgccgccc aaatcacaga
    10741 tgcggatgta gtcttcccaa gcattttcat cgtgatctac ctgtgtacgt ttccagaatt
    10801 ggagggcaca aacttgggcc aaggtatagt cgatgtagta gaatggacta gcaaagatat
    10861 gaccttgacg ataccagaag ataccgcggt tgagggcttc tgactcggaa tagtcacggt
    10921 ctggcaagta gaggtcttgg agttttttcc aagttgcctt gcgttctgct ggtgtcatct
    10981 ctgggcgttc atagacttcg tgctggaagt ggtctaccaa gacaccgtaa ggcaagaaga
    11041 gaagggcact tgccaagtga gtaaatttat atttatccac ttgttccttg aagaaacggt
    11101 ccatccatgg ccaggtcata aattccatag acatggagtg gatttcacag gtttcgtagg
    11161 ttggccaaac aacttctgga ctttgaatcc aacgcgaacg atagacttgg aaggcgtgac
    11221 ctgcttcgtg ggtcaagaca tcaatatcac cgctggttcc gttgaagttg gagaagatga
    11281 atgggctctt gaagtcaggg atataggtac agtagccacc gctgtttttg cctggttttg
    11341 cgaccaagtc caagagttca tgctcaatca tgaaatcgaa gaactcgcct gtttctgcgg
    11401 acaattcgcg gtacatgtct tgggcttggc tgacgataaa gtcggggtca ccttgaggaa
    11461 cagcatttcc atccaagaac tcaaggttta ggtcgtagtg tttgaggctt ggcacctgca
    11521 agcgattggc ttggcgttga cgcagatttt gtacaatcgg tacgatatgc ttgaggattt
    11581 cttcacggta aaccttaacc atgtcacgat tgtaatcgaa acggttcatc ttgaggtagc
    11641 cgtattccac atagtccttg aagccaagtt tgtgggcgat ttctgtgcgg acttttacta
    11701 attcatcgta aacacggtca aaatcagctt ccttgctttc aaagaaggta gttgtggcag
    11761 cagaagcagc cttgcggact tcacggtcgg ttgattgacc gaatggcccc atttgtgaca
    11821 agttgtaggt ctgaccttgg aaatcaatct ctgcaccagc aatcagcttg ctgtactcat
    11881 cggtcaattc attttctttt tgcaataatg gaatgacgtc tgatgagaag gtcttgagct
    11941 tgttttctgc ctgcatgaag aaggtttgag gcaagatgtc tgacagttct tccttgtacg
    12001 gcgtctggac aatgatacgg tagtagttgg tggtcaattc ttcaaaaagt ggcgaatatt
    12061 cattccaaaa cttggtttct tcattgtaga actcatcgtt catgtcaata gtatgacgga
    12121 tcatccagag attgtactgg gtatcgacca ggttgagtaa tttggtaacg gctgccacaa
    12181 gtgtgcgagt tgtttccaag tcacttgcct gagccaactg gtcggtcagg tcagtaaatt
    12241 gagccttgat agcttcataa tctggacgga cataggtata gtctgaaaat ttcatatgtt
    12301 tctccttttg tattgctacc ttctatctta ctctttttga aaacgtttgg caaatcccga
    12361 cccgtccatg ttcacaagtc tttctattta tggtaaaatg taggagatta ttagaaaaaa
    12421 tgaggttgta gacatgtcta aatttttagt ttttggtcac caaaatcctg atacagatgc
    12481 cattgcatca tcatacggct gggctcactt ggagcgtgaa gtgtttggtc gtgatgcgga
    12541 agcagtagtt ctaggaacgc caaatgaaga aactgctttt gctcttgact attttggtgt
    12601 tactgcaccg cgcgtggttg agtctgcaaa agcagaaggt gttagccaag tcatcttgac
    12661 tgaccacaat gaattccaac agtctatcgc agacatcaag gaagtggaag tggcagctgt
    12721 cattgaccac caccgtgtcg caaactttga aacggcaaat ccattgtaca tgcgtttgga
    12781 gccagtaggt tcagcatcat caatcgttta ccgtgccttt aaagaaaacg gagtaatacc
    12841 tccaaaagaa gtagctggac ttctcctatc aggtttgatt tcagataccc tcttgcttaa
    12901 atcgccaact actcatgtaa cagatccaca ggtagcagct gaattggctg aaattgctgg
    12961 tgtcaactta gaagaatacg gtttggcact cttgaaagct ggtaccaacc ttgccagcaa
    13021 gtcagcagaa gaattgattg acatcgatgc caaaacattt ggcttgaatg gcaatgacgt
    13081 gcgtgtagcc caagttaaca cagtggacat tgcggaagtc ttggaacgcc aagcagaaat
    13141 cgaagcagct atgacagcag catcagtagc aaatggctac tctgactttg ttttgatgat
    13201 tacagacatc gttaactcaa actcagaaat ccttgcgctc ggtagcaaca tggacaaggt
    13261 agaagcagcc ttcaacttca agttggaaaa caaccacgcc ttccttgcag gtgccgtttc
    13321 acgtaagaaa caagtggtgc cacagttgac tgacgctttc aacgcctaat gaatttttct
    13381 acctacctca acgtgaagtc ggtaggatga tcttacctag caccttcggg tgcttttttt
    13441 attgtgagga caatcatgtt ttatgaagtg atagttaaca aaataaacaa gtggcatcat
    13501 gacaaataaa cccactccta tttaatactc ttcgaaaatc aaaatcagac attgttgact
    13561 tgatttgata aacttcagtt ctatctgcat atgcatcgcc tagtttgatt ttcattgagt
    13621 ataagttgac gaattaaagc gagcactccg agataaaaac aatgatctgc atcatagaaa
    13681 aattcaggcg cttgttcttt actttgaatg tgccataact tagaaattgt atttacaagt
    13741 aataaaagaa aaactaaatg actatgagaa ccagcaaagt ttttgcgaaa tgtagcatgc
    13801 tatttattac agacaactgt gaaacagata aaaaactaat gaaaaacaat gttctatgag
    13861 atgttttttt tataataaaa ctaggacaat atgtgtcgtt aattgttaat acagatataa
    13921 ggagaaaaga tgaatagcaa gattttttcg ttgagaaaaa gtaagatggg tttagtttcg
    13981 gtggcaattg cttttctatg gattggtaca gggatgaata tggaaaccgc aatggctgag
    14041 gagactgacg ctacagctct tgaaactcaa ttagaaagca cggaatcatc gcttaccaat
    14101 acagtttcgg aaaatgctga agctgaggaa gtgactgatg aggtaccgag tgaagaaaaa
    14161 aaaatcggaa gagatggagg atatggagga agaactttca tttattgaaa accatctaga
    14221 ggttgctccg attcaagctg gagatcaaac catctcaggg aataccactc ctggtggata
    14281 tgtagcgatt acgatagatg gggaagcaat tacttctatt gagaatattt tggaagcaga
    14341 tgataaggga gatttttctt atcggttgag taaaccactt gctcacagcc aaactgtgga
    14401 aattagtgct ttgccgaaac agttttggac tctagaggca gattctgaag agcgtaaggt
    14461 agtagtgagg actaatcgac atccagaggc ttatgaaatt ccagcaaaaa gattagaaaa
    14521 aacatctaat ggaatgcatc aagtgttcat cgaaccagtt tttgaacata cgagcaaagt
    14581 tattggtcat acctctgtca aaggttcagt ctatctatca ataaatggta gttttgtctc
    14641 tgataagaca ctaattgatc ctaaagatgg acggtttgag gttacttttt ccgagagttt
    14701 agcaggttca aaatttaaag cagatgatag attggttttg tcttttgtat cagaagatgg
    14761 tcagccggtg attactaata ctattgtaaa accattggta aaagaaaaag tatcttcaca
    14821 aatgacagta aaacctttat caagtgcgac ttcagttttg gaaggaacta catttccttt
    14881 aggtcgtgtg catctataca atgctgatac ttcagagttt atcatggaag ctattgctga
    14941 tgagacaggt cactataaga ttgctttgcc tgccctacaa tccgaggata agtactacag
    15001 attgactcac aatcaacaag aggacttggt atctgtccat cttgatacag ttgatggttc
    15061 aagtatatta ttggataaat ctgttatggc atctttagca acttatttac aagatgcaga
    15121 tatggatgaa gcgacagatg aagatcctat cattgtacct aaactgcata ataaaaaaga
    15181 ttatattgtc ggtcgaacga tacatcttaa tgcctacgtt cgcatggttt cgtcaatcaa
    15241 aggaaaacag tatcctccag ttcaagtgga cgaattagga ttttttggtt tccaaattca
    15301 agatttacaa ttgccttttg aaaaaggtga gagaattcgc tttgaaatca ttgacccggt
    15361 tacaaataat atcatcgcta gtaaggaaga agttgtaggg caatatttgg aagatgaaga
    15421 cgtgatggat ttaccatttc aagtagaaaa agtcactaca gatcatggtt acatcagtgg
    15481 caaaacagct ccagatgtaa tgattgaact agtatcaact cagaatggcg aggagataat
    15541 tggtaaaact tcaactgatt caacaggtcg attcgaattt gatttgggta gtcgtgtttt
    15601 aaaaaatgga gaaaccttat cgtttagagc gtttgataaa gaaggtgaac aggtagcttg
    15661 ggaagtcgta acggttcaaa aaggaaatgg tcaccgcatt aataaaccag ataaaaagga
    15721 cgagaaggaa gagcaaccta gcaaagaaat taccaaaaat atcgaacaat caaacacact
    15781 tgagcaaact actttgccac ctgtacgcca aacgctgact gacaaaaaag tagagcaaaa
    15841 tgcagagcca tcaaaagaag aaacggtttc tatttttgat gattcgaaaa aagatatgcc
    15901 tactaagcaa gagaaaatgg ctcgtactgt aagagacaaa gggacaaaag gaaacgtatc
    15961 tgtgcatgat agtggtgaga atacccaagt tcaaagcctg cctaagaccg gtgaaaaaac
    16021 gagcttggtt gccaatataa tgttatcgat catattattc ttatttgctt tattcattgg
    16081 caagaaaaag ataacagaaa gtgagtaaaa ggcgatgaca aagctctctc aaaaattcgt
    16141 ttgcgacaga tgagaggcat tgtgtagctt taaattaaaa gagttaaaat ttttctttca
    16201 atgaattatt tgcttataga ggtgaaagta gagtttga
//
LOCUS       DBNFCO010000047        15069 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.047, whole genome shotgun sequence.
ACCESSION   DBNFCO010000047 DBNFCO010000000
VERSION     DBNFCO010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 15069)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15069)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15069
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.047"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            6..1142
                     /gene="dnaN"
                     /locus_tag="AC1PIV_001295"
     CDS             6..1142
                     /gene="dnaN"
                     /locus_tag="AC1PIV_001295"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HIP6612316.1"
                     /translation="MIQFSINKNIFLQALSITKRAISTKNAIPILSTVKITVTSEGIT
                     LTGSNGQISIEHFISIQDENAGLLISSPGSILLEAGFFINVVSSMPDLVLDFNEIEQK
                     QIVLTSGKSEITLKGKEAEQYPRLQEVPTSKPLVLETKVLKQTINETAFAASTQESRP
                     ILTGVHFVLTENKNLKTVATDSHRMSQRKLVLDTSGDDFNVVIPSRSLREFTAVFTDD
                     IETVEVFFSNNQILFRSEHISFYTRLLEGTYPDTDRLIPTEFKTTAIFDTANLRHSME
                     RARLLSNATQNGTVKLEIANNVVSAHVNSPEVGRVNEELDTVEVSGEDLVISFNPTYL
                     IEALKATTSEQVKISFISSVRPFTLIPNNEGEDFIQLVTPVRTN"
     gene            1234..2115
                     /locus_tag="AC1PIV_001296"
     CDS             1234..2115
                     /locus_tag="AC1PIV_001296"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001727 - lipid kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol/lipid kinase family protein"
                     /protein_id="HIP6612317.1"
                     /translation="MTLYILANPNAGSHTAEHIIFKIKESYPQLAVNIFMTVGPEDEK
                     SQIEAILKEFVSSEDQLMILGGDGTLSKALRFWPASLPFAYYPTGSGNDFAKAMNITS
                     LYRSVDAILERKTSRIYVLNSSYGTVVNSMDFGFAAQVINGSTNSILKKILNKVKLGK
                     LTYLFFGIKTLFSKQAINLELTLDEKSYQLDNLFFISVANSLYFGGGIMIWPTASAKK
                     KEVDIVYFKNGNFYQRLQSLLALLTKRHESSHTIQHLTGVDVVLKSKEKLLLQIDGET
                     CTANEVTLTYQERSMYL"
     gene            2125..2328
                     /locus_tag="AC1PIV_001297"
     CDS             2125..2328
                     /locus_tag="AC1PIV_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HIP6612318.1"
                     /translation="MYQLGTFVEMKKPHACVIKSTGKKANKWEVIRLGADIKIRCTNC
                     DHVVMMSRHDFERKMKQVLPSEA"
     gene            2432..2791
                     /locus_tag="AC1PIV_001298"
     CDS             2432..2791
                     /locus_tag="AC1PIV_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIP6612319.1"
                     /translation="MKQLAQQIRVLRTAKNLSQDELAEKLYISRQAVSKWENGEATPD
                     IDKLVQLAEIFGVSLDYLVLGKEPEKEIVVEQRGKMNGWEFLNEESKRPLTRGDVVLL
                     IFLAVMLLGGLFIKHYF"
     gene            2877..3992
                     /gene="ychF"
                     /locus_tag="AC1PIV_001299"
     CDS             2877..3992
                     /gene="ychF"
                     /locus_tag="AC1PIV_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HIP6612320.1"
                     /translation="MSLTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTELIIPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPIADIDTINLELILADLESINKRYARVEKMARTQKD
                     KDSVAEFAVLEKIKPVLEDGKSARTVEFTDEEQKIVKQLFLLTTKPVLYVANVDEDKV
                     ADPEAISYVQQIRDFAATENAEVVVISARAEEEISELDDEDKGEFLEALGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQCAGIIHSDFEKGFIRAVTMSYDD
                     LMTYGSEKAVKEAGRLREEGKEYVVQDGDIMEFRFNV"
     gene            4150..4719
                     /gene="pth"
                     /locus_tag="AC1PIV_001300"
     CDS             4150..4719
                     /gene="pth"
                     /locus_tag="AC1PIV_001300"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - peptidyl-tRNA hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HIP6612321.1"
                     /translation="MTRLIIGLGNPGDRYFETKHNVGFMLLDKIAKRENVTFNHDKIF
                     QADIATTFIDGEKIYLVKPTTFMNESGKAVHALMTYYGLDATDILVAYDDLDMAVGKI
                     RFRQKGSAGGHNGIKSIVKHIGTQEFDRIKIGIGRPKGKMSVVNHVLSGFDIEDRIEI
                     DLALDKLDKAVNVYLEEDDFDTVMRKFNG"
     gene            4719..8213
                     /gene="mfd"
                     /locus_tag="AC1PIV_001301"
     CDS             4719..8213
                     /gene="mfd"
                     /locus_tag="AC1PIV_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HIP6612322.1"
                     /translation="MNILDLLHKNKQINQWQSGLNQSTRQLLLGLSGTSKSLIMATAY
                     DCLAEKIMIVTATQNDAEKLVADLTAIIGSENVYNFFTDDSPIAEFVFASKERTQSRI
                     DSLNFLTDSTSSGILVASIVACRVLLPSPETYKGSKIQLEVGQEIEVDKLVKNLVNIG
                     YKKVSRVLTQGEFSQRGDILDIFDMQSETPYRIEFFGDEIDGIRIFDVDSQKSLENLD
                     EISISPASDIILSSEDYSRASQYIQTAIEQSTLEEQQSYLREVLADMQTEYRHPDLRK
                     FLSCIYEQSWTLLDYLPKSSPLFLDDFHKIADKQAQFEKEIADLLTDDLQKGKTVSSL
                     KYFASTYAELRKYKPATFFSSFQKGLGNVKFDALYQFTQHPMQEFFHQIPLLKDELTR
                     YAKSNNTVVIQASSDVSLQTLQKNLQEYDIHLPVHAADKLVEGQQQVTIGQLASGFHL
                     MDEKLVFITEKEIFNKKMKRKTRRTNISNAERIKDYSELAVGDYVVHHVHGIGQYLGI
                     ETIEISGIHRDYLTVQYQNSDRISIPVEQIDLLSKYLASDGKAPKVNKLNDGRFQRTK
                     QKVQKQVEDIADDLIKLYAERSQLKGFAFSPDDENQVEFDNYFTHVETDDQLRSIDEI
                     KKDMEKDSPMDRLLVGDVGFGKTEVAMRAAFKAVNDGKQVAILVPTTVLAQQHYANFQ
                     ERFAEFPVNVDVMSRFKTKAEQEKTLEKLKKGQVDILIGTHRLLSKDVVFADLGLLVI
                     DEEQRFGVKHKERLKELKKKIDVLTLTATPIPRTLQMSMLGIRDLSVIETPPTNRYPV
                     QTYVMETNPSVIRDAMLREIDRGGQVYYLYNKVDTIEQKVSELKELVPEATIGYVHGQ
                     MSEIQLENTLYAFVEGEYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSSRIAYAYLMYRPDKSLTEVAEKRLEAIKGFTELGSGFKIAMQDLSIRGAGNILG
                     AAQSGFIDSVGYEMYSQLLEQAILEKQGKATQRQKSNSEVNLQIDAYLPSDYIGDQRQ
                     KIEIYKRIKNIDSRVNYQELQEELIDRFGEYPDVVAYLLEIGLLKSFLDQVFCHTVLR
                     RQHQVTVTFEPMAGQIFLTQDYFEALSVTNLKAQITENKGKLAVVFNIQQKKEYEILE
                     ELISFAEKLKEIKARKAE"
     gene            8263..8535
                     /locus_tag="AC1PIV_001302"
     CDS             8263..8535
                     /locus_tag="AC1PIV_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HIP6612323.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIQFGNKLLTVKVLEMKDSTKKEDALKMYEIISEKRIEKDEEI"
     gene            8522..8890
                     /locus_tag="AC1PIV_001303"
     CDS             8522..8890
                     /locus_tag="AC1PIV_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsB family cell division protein"
                     /protein_id="HIP6612324.1"
                     /translation="MKKSKILQLNNAFIQSERKKTQHQLAERQQKNRFMGAILILVIF
                     LFMLPAYNLVGTYTNIQQQEKKLAELEKNYEELTKEQKQEAEMVAKLKNEEYAAKYVR
                     AKYQYSKEGEFVYNIPGLPK"
     gene            8887..9000
                     /locus_tag="AC1PIV_001304"
     CDS             8887..9000
                     /locus_tag="AC1PIV_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0009 family protein"
                     /protein_id="HIP6612325.1"
                     /translation="MTESIFKIVEQFLQHSDEKLEELNQKNRELKLEENES"
     gene            9013..10293
                     /locus_tag="AC1PIV_001305"
     CDS             9013..10293
                     /locus_tag="AC1PIV_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HIP6612326.1"
                     /translation="MQKKLLVWLLPVLFGWQVVDSTEIPFELTAQEEYELTHTIYDQY
                     FQTIPQNPNVFQTENLYSDEELTIAGGQLQPNQHFSITDVLVNSKKELVFQIDDKGYI
                     LASRHLLFDDVIVTETTVEQTYWTKKGFTLLTSPIANEATEIKNDLQPYQAVMVSKIV
                     TTSLGDFAYVTDKGWIAVNNLSKTDNRVEAVQELLTNKYSKDTIGIYVKQLSTGQTAG
                     VNQEKLFYSASIAKLPILYYVQEQLNAGYIDLTTKVKYTAESISFPGAYVAGGSGSLS
                     KTPDNKDYSVEELINKTAKESDNVASNLLSYYVANKFDSNFYQVITAKTGSEWSMVTR
                     ETSAEIAGKMMEALYIQNGYVLESLLSTQFDNQRISKDISVPVAHKIGDADDVKHDVA
                     IVYAGSPFVLSIFTDKSNYDEITQIANDIYRILK"
     gene            10294..11562
                     /gene="tilS"
                     /locus_tag="AC1PIV_001306"
     CDS             10294..11562
                     /gene="tilS"
                     /locus_tag="AC1PIV_001306"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HIP6612327.1"
                     /translation="MKDRFLKVTLDGHFFDKHKKVLVAVSGGLDSMNLFHLLYECKQV
                     LGIELGIAHINHGQREESVIEEKYLRQLAEESNVPFYLSYFEGVFSEEAARKWRYGFF
                     ATIMEKEGYTALVTAHHADDQAETVFMRLIRGGRLRHLSAIQPTQPFATGELIRPLLS
                     FKKADFEKLFHFEDCSNADFKYFRNRVRNDYLPKLKQENPKIELTLNNLAVDTNNLFQ
                     ALRDLTQDLSVTDVMSFQQQTPAVQSYLLEEYLEKFPDLQLSRPQFNEVLHILRSKAN
                     YYHLLKNDYMLEKDYHRFQIYKIGPETDSQPEKIMIESEGIFSYGSYIFSLNHPLEEA
                     DSILYFPTENPIVVRRRQAGDTILINGVNKKLRRWFIDNKISQKVRQNALIIEQNGEI
                     YGITNLVSSDLSKSVKNDIIKATLYIKMKE"
     gene            11570..12112
                     /gene="hpt"
                     /locus_tag="AC1PIV_001307"
     CDS             11570..12112
                     /gene="hpt"
                     /locus_tag="AC1PIV_001307"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HIP6612328.1"
                     /translation="MLDKDIKKILVSEEEIVAKCKELGQILATDYADKNPILVGILKG
                     SIPFMAELMKHIDAHVETDYMVVSSYHGGTESCGTVKIIKDLDNSVAGRYIIFVEDII
                     DTGRTLKELKELFALRQAASIKIATLLDKPEGRVVEIEPDYTCFTIPNEFVVGFGLDY
                     DENYRNLPYVGVLKEEVYTK"
     gene            12134..14107
                     /gene="ftsH"
                     /locus_tag="AC1PIV_001308"
     CDS             12134..14107
                     /gene="ftsH"
                     /locus_tag="AC1PIV_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HIP6612329.1"
                     /translation="MNNQPNKGFIKNPFLIILVIATIVTAFQFFNAGQQVATQEISYS
                     QVVTELKNNNVSEITYQPNSSVIEITGKYKTEQEAKDELASSIKLFQVSSKVKYKNFK
                     SLILPSETNLSELQALANENGVKVAIKPESSNGLWLNIIFNLLPLVIAGVFFMMMMNQ
                     GGGGARGAMNFGRNKAKALEQSNIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLG
                     ARIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFED
                     AKKAAPAIIFIDEIDAVGRQRGVGMGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAAT
                     NRSDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAADVDLKLVAQQTPG
                     FVGADLENVLNEAALVAARRNKTVIDASDIDEAEDRVIAGPSKKDRQVSAKEREIVAY
                     HEAGHTIVGLVLSNAREVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMG
                     GRVAEEIIFNTQTTGASNDFEQATQMARAMVAEYGMSDKMGPMQYEGSHAMFGGQTTQ
                     KHISEQTAYELDNEVRDLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSVQIKSL
                     YETGKMPENIERDDEDVHPLSYEEVKEKINTKE"
     gene            14445..14915
                     /locus_tag="AC1PIV_001309"
     CDS             14445..14915
                     /locus_tag="AC1PIV_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HIP6612330.1"
                     /translation="MEFEKVYASVKGIVNKARKEFYIKLWDRDDWEQEGMMTLFELLE
                     AQPWLVDEQVQLYCYFKVKFRNRIKDRIRKQESQKRKFDRMPHEDIYELSHAIQSPGL
                     INDELLMLRGALRDYRKNLSNDQLDKYEKLISGQCFNGRREMIRDLQIHLKDFR"
BASE COUNT         5114 a         2536 c         3039 g         4380 t
ORIGIN      
        1 aatccatgat tcaattttct attaataaaa atatatttct acaagcactt agtattacta
       61 aacgggcaat cagtacaaaa aatgctattc caattctttc aacagtaaaa attacagtaa
      121 ctagtgaagg aatcacttta actggttcaa atggacaaat ctcgatagaa cattttattt
      181 ctattcaaga tgaaaatgca gggcttttga tcagttctcc aggttccatt ctcttagaag
      241 ctggtttctt tattaatgtc gtatccagta tgccggattt ggtccttgac ttcaatgaaa
      301 ttgaacaaaa gcaaatcgtt ttgacaagtg gtaagtctga aatcacatta aagggaaaag
      361 aagcagaaca gtatcctcgt ttacaggaag ttccaacttc aaaaccattg gtgttagaaa
      421 ccaaagtatt aaaacaaaca attaatgaaa cagcatttgc agcttctaca caagaaagtc
      481 gtcctattct tacgggtgtt cattttgttt taacagaaaa taaaaatcta aaaactgttg
      541 caacagattc acaccgtatg agccaacgga aattggtcct tgatacctct ggtgatgatt
      601 ttaatgttgt cattccaagt cgttctctcc gtgaatttac tgcagttttt acagatgata
      661 ttgaaacagt agaagtcttc ttttcaaata atcaaatcct ttttagaagc gagcatatta
      721 gcttctatac acgcttatta gaaggtacct accctgatac cgaccgctta attccaactg
      781 agtttaaaac aactgcaatt tttgatactg caaatcttcg tcactcgatg gagcgtgctc
      841 gtcttctttc aaatgcaacc caaaatggta cagtaaaact agaaattgct aataatgttg
      901 tatcggctca tgtaaattct ccagaagttg gacgtgtgaa tgaggaatta gatactgtag
      961 aagtatcagg tgaagattta gtaatcagct ttaacccaac ttacttgata gaagcattga
     1021 aagccacaac tagtgaacaa gtgaaaatta gctttatctc ttctgtccgt ccatttacat
     1081 tgattccaaa taatgaaggg gaagatttta ttcaattggt tacaccagtt cgtaccaact
     1141 aaataatatt aagaacggct aaactagccg tttttatgtt atactaaaaa atagcaccta
     1201 gcttattttt atatatttag tgatggggaa taaatgacgt tatatatatt agctaatcct
     1261 aatgctggta gccatactgc tgaacatatc atattcaaaa taaaagaaag ttatccacag
     1321 cttgcagtta acatttttat gacagttggt cctgaggatg aaaaaagtca aatagaggct
     1381 attttaaagg agtttgtcag tagtgaagat caattaatga ttttaggcgg agacggcaca
     1441 ctatctaaag ctttgcgttt ttggccagct agtctaccgt ttgcttatta tccaacagga
     1501 tctggaaatg attttgctaa ggcaatgaat ataacatcgc tatatagaag tgtagatgcc
     1561 attttagaga gaaaaacaag tcggatatat gttttaaaca gttcatacgg aacggttgta
     1621 aacagtatgg attttggctt tgcagctcaa gttatcaatg gttcaacgaa ttcaattttg
     1681 aaaaaaattc tgaacaaggt aaaacttggg aagttaactt atctattctt tggtattaaa
     1741 acattatttt caaaacaagc tataaactta gaattaactc ttgatgaaaa atcttatcag
     1801 ttagataatc tcttttttat ttctgtagca aatagtcttt attttggtgg aggaatcatg
     1861 atatggccaa cagcaagtgc taaaaagaag gaagtagata ttgtttactt caaaaatgga
     1921 aatttctacc aacgtctaca atcattgtta gccttattaa cgaagaggca tgaatcttct
     1981 catacgattc agcatttaac aggggtagat gtagttttaa aatcaaaaga aaaattatta
     2041 ttgcaaatag atggagagac atgcactgca aatgaggtaa cgttaaccta tcaggaaaga
     2101 agtatgtatc tttaaggagg aagtatgtac caattaggaa cctttgtcga aatgaaaaag
     2161 ccccatgcct gtgtcatcaa atcgaccgga aagaaggcta ataaatggga ggttatccgt
     2221 ctaggagcgg atattaaaat ccgctgtacc aactgtgacc atgtcgttat gatgagccgg
     2281 catgattttg aacgaaaaat gaaacaagtt ctgccaagtg aagcctagtt gacagtttgc
     2341 aactactggt tgcgaatttt tcctaaaaag tgctagtcaa ctgttccttt ctaaactata
     2401 atagacttag aaaaaagagg aggaaatgat catgaagcag ttagcacagc aaattcgagt
     2461 tttacgcaca gccaagaacc tatcccaaga tgagttggca gagaaactct atatttcccg
     2521 tcaggctgtt tccaagtggg aaaatggtga agccacacca gatattgaca aactggtcca
     2581 gctggcagaa atctttggtg tcagtctgga ttatctggtt ttagggaaag aacctgagaa
     2641 ggaaattgtg gtggaacaac gaggaaaaat gaatggttgg gaattcttga acgaagaatc
     2701 caaacgacct cttacaagag gagatgttgt ccttctcatt tttcttgcag ttatgctttt
     2761 aggtggatta tttattaagc attattttta acgaagcttg ccaaacagca agctttttct
     2821 ctacttttct gctataatag tcatgattga atttttaatt ggagagtaaa aaaaacatgt
     2881 ctttaacagc aggaatcgtc ggtttgccaa acgttggtaa atcaacccta tttaacgcaa
     2941 ttaccaaggc aggagcagaa gctgcaaact accctttcgc aactattgat ccaaacgtcg
     3001 gcatggtaga agtgcccgat gagcgtctgc agaagttgac cgaactcatc atccctaaaa
     3061 agacagtgcc aacgactttt gaatttactg atattgctgg tatcgtaaaa ggtgcttcta
     3121 aaggtgaagg acttggaaat aaattcttgg ccaatatccg cgaagttgat gcgattgtcc
     3181 acgttgtgcg tgcctttgac gatgaaaatg tcatgcgtga acaaggccgt gaagatgcct
     3241 ttgtggatcc aatcgctgat attgatacca ttaacctaga attgattttg gcggacctag
     3301 agagcatcaa caagcgttat gcgcgtgtag aaaaaatggc ccgtacgcaa aaagacaaag
     3361 attctgtcgc agaatttgca gttcttgaaa aaatcaaacc tgtcctagaa gacggaaaat
     3421 ctgcccgcac agttgagttc acagatgaag aacaaaaaat cgttaagcaa ctcttcctct
     3481 tgaccactaa acccgtcctc tatgttgcca atgttgatga agacaaggta gcagatcctg
     3541 aggctatcag ttatgttcag caaatccgtg actttgcagc aacagaaaat gcagaagtgg
     3601 tggtgatctc tgcgcgtgct gaagaagaaa tttcagaact cgacgatgaa gacaagggcg
     3661 agtttttaga agcactcgga ttaacagaat ctggcgtgga caaattaaca cgtgcagcct
     3721 atcacttgct tggtctaggc acctacttta cagcagggga gaaggaggtt cgtgcttgga
     3781 ccttcaaacg tggtatgaaa gctcctcagt gtgcaggcat tatccattca gacttcgaaa
     3841 aaggttttat ccgtgccgtt accatgtcat acgatgattt aatgacctac ggctctgaga
     3901 aggctgttaa agaagcagga cgccttcgtg aagaaggaaa agagtacgtg gttcaagatg
     3961 gggacatcat ggagttccgc tttaacgttt gattgctaaa ctgtccttat tcttcgttgt
     4021 tttaccttgc cataccatca gtattgtctg cggtttcaac gcctagacta agaacagttt
     4081 atcgcatcaa agaggatgat tacttggttg gaaagctttt tccagccttt tggtatttaa
     4141 ggagaaaaaa tgacacgatt gattatcggt ttgggaaatc ccggagaccg ctattttgaa
     4201 acaaaacata acgttggttt tatgctgctg gataagattg ctaagcgtga aaatgtgacc
     4261 tttaaccacg ataagatttt ccaagcagac attgccacaa cctttattga tggtgaaaaa
     4321 atttacctgg tcaaaccaac gactttcatg aatgaatcag gtaaggctgt ccatgcctta
     4381 atgacttatt atggtctgga tgcaactgat attttagtag cttatgacga cttggacatg
     4441 gctgttggaa aaatccgttt ccgtcaaaaa ggctcagctg gtggccacaa tggtatcaaa
     4501 tccattgtca agcatattgg aacacaggaa tttgaccgta tcaagattgg tattgggcgt
     4561 cctaaaggaa aaatgagcgt tgtaaaccat gtcttgtctg gctttgatat agaggaccgt
     4621 attgaaatcg acttagcact agataaactt gacaaggctg tcaacgtata tctcgaagaa
     4681 gatgattttg atacagtaat gagaaagttt aacggataat gaatatactc gatttacttc
     4741 acaagaacaa gcaaatcaat caatggcagt caggattgaa tcaatcaaca cgtcagttat
     4801 tattaggact atctgggact agtaagtcac ttataatggc gactgcctat gattgtttgg
     4861 ccgaaaagat tatgattgtg actgctactc aaaatgatgc tgagaaatta gttgcagatt
     4921 taacagccat tattggaagt gagaatgttt acaacttttt tacagatgat agtcctattg
     4981 ccgagtttgt ttttgcatca aaagaacgga ctcaatcaag gattgacagt ttaaatttct
     5041 tgacagattc taccagttca ggaattttag ttgctagtat agttgcttgt cgggtcttat
     5101 tgccgagtcc tgagacttat aaaggttcta aaatacagct tgaagttggt caagaaatag
     5161 aagttgacaa acttgtaaag aaccttgtca acatcggcta caaaaaagtg tctcgtgtat
     5221 taacccaggg agaatttagc caacgaggtg atattctaga tatttttgac atgcaatcag
     5281 aaacacctta ccgaatagaa ttttttggag atgagattga tggcattcgt atctttgatg
     5341 ttgacagtca aaaatcctta gaaaatctag acgaaatctc gatctctcca gcttccgata
     5401 tcattttgtc ttcagaagac tatagtagag ctagccaata cattcagaca gctattgaac
     5461 aatcgactct agaggagcaa cagtcttact tacgagaagt cttagctgat atgcagacgg
     5521 agtaccggca tccagatttg cgtaaattct tgtcctgtat ctatgaacaa tcatggacat
     5581 tgttggatta cttgccaaag agttctccct tatttttgga tgattttcat aaaatcgctg
     5641 ataagcaggc tcaatttgaa aaagaaattg cagacttgtt gacagatgat ttacagaagg
     5701 gtaaaacagt gtcaagtttg aaatattttg cctcaactta tgctgaattg agaaaataca
     5761 aacctgccac cttcttttca agttttcaaa aaggtttagg aaatgtaaag tttgatgctc
     5821 tttatcaatt cacacagcat cctatgcagg aatttttcca ccagattcca ctgttaaaag
     5881 atgaattgac tcggtatgcg aaatcaaaca ataccgttgt tattcaagcg agttctgatg
     5941 taagtttaca gactttacag aaaaatttac aagagtatga tatccatctt ccagtacatg
     6001 cagcagataa gttagtagaa ggtcagcaac aggttacgat tggtcagtta gcttcaggtt
     6061 ttcatttgat ggatgagaaa ctagttttca tcactgaaaa agagattttc aataagaaaa
     6121 tgaagcgtaa gacacgtaga accaatattt ctaacgctga acgtattaag gactatagtg
     6181 aattagcagt tggtgactat gttgttcacc atgttcatgg tatcggtcaa tacttaggaa
     6241 ttgagactat tgaaatttca ggcattcatc gtgattattt aacggttcaa tatcaaaact
     6301 ccgatcgcat ttctattcct gtagaacaaa ttgatcttct ctccaaatac ttagcgtccg
     6361 atgggaaagc tccaaaagtt aataaactaa acgatggccg gttccaacga accaagcaaa
     6421 aagttcagaa gcaagtggag gatattgcag atgatttgat taagctttat gcggagcgta
     6481 gtcagctgaa aggctttgcc ttttcacctg atgatgaaaa tcaagttgaa tttgacaact
     6541 actttacaca cgtggaaacc gatgaccaac tccgttccat tgatgaaatc aaaaaagaca
     6601 tggaaaaaga ctctccaatg gaccgtctgt tagtaggaga tgtcggattt ggtaagacag
     6661 aggtagccat gcgcgctgct ttcaaagcag tcaatgatgg caagcaagta gctattcttg
     6721 tacctacgac tgttttagcc cagcaacact atgctaattt ccaagaacgg tttgcagaat
     6781 ttcccgtcaa tgtggatgtt atgagtcgtt ttaaaacaaa ggcagagcag gaaaaaacac
     6841 ttgagaagtt gaaaaaaggc caagttgaca tcttgattgg tacccatcgc cttctatcaa
     6901 aagatgttgt ttttgctgat ttaggtttac tggttattga cgaagagcaa cggtttggtg
     6961 tcaagcataa ggaacgcttg aaggaactga aaaagaaaat agatgtccta accttgactg
     7021 caactccgat tcctcggaca ttgcaaatgt ccatgctggg aatccgcgac ttatcagtaa
     7081 ttgagactcc accgacaaat cgctatcctg tacaaactta tgtgatggaa acaaatcctt
     7141 ccgttatccg agatgcaatg cttcgagaga tagatcgcgg aggtcaggtt tactatcttt
     7201 acaataaagt tgataccatt gaacagaaag tgtctgaatt aaaagaattg gttccagaag
     7261 ctactatagg atacgtccat ggacaaatgt cggagatcca attagaaaat actctctatg
     7321 cttttgtaga gggtgaatat gatattctag tgaccacaac aatcatcgaa acaggtgttg
     7381 atattccaaa tgctaataca ctgtttattg aaaatgcaga tcatatggga ctgtcaactc
     7441 tttatcaact tagaggacgt gttggccgtt ccagtcggat tgcctatgcc tatctcatgt
     7501 accgtccaga caagtccttg acagaagtag ctgaaaaacg tttggaggca atcaagggct
     7561 ttacagaact aggatcaggt ttcaagattg ccatgcaaga tttgtccatt cgtggtgcgg
     7621 gaaatatttt aggtgctgct cagtcaggtt ttattgattc tgtgggatat gagatgtatt
     7681 cacaattgct ggaacaagct atcttggaaa aacaaggtaa ggcaacccaa cgtcagaaga
     7741 gtaattccga ggtcaattta cagattgatg cctatttacc aagtgattat attggtgatc
     7801 agcgacaaaa aattgaaatt tacaagcgta taaagaatat tgacagtcgt gtcaactatc
     7861 aagaattgca agaagaattg attgaccgtt ttggagagta tcctgatgta gtagcctact
     7921 tgcttgaaat cggtctactg aagtcatttt tagaccaagt tttctgtcat acagttctta
     7981 gacgacaaca tcaagtgaca gtaacattcg aacctatggc tggtcaaatt ttcctaacgc
     8041 aagattactt tgaagcttta tctgtgacaa atttgaaagc tcagataacg gaaaataaag
     8101 gaaaactagc tgttgtgttt aacattcaac agaaaaaaga atatgaaata ttagaggaat
     8161 tgatttcttt tgccgaaaaa ttaaaagaaa ttaaagcaag gaaggcagaa taaatttctc
     8221 aaataccttg aaaaatggta aaataatgaa ctgaggtaaa gtatgagact agataaatat
     8281 ttgaaagtat cccgcattat caagcgtcga acagttgcga aggaagttgc cgataaagga
     8341 cgaataaaag tcaatgggat tttggcgaaa tcttcaacag atttaaaagt aaatgatcag
     8401 gttgaaatcc aatttggtaa taaactactc actgtaaaag tacttgaaat gaaagattcg
     8461 actaaaaaag aagacgcact gaaaatgtat gaaattatca gtgaaaaaag gatagaaaaa
     8521 gatgaagaaa tctaaaattc tacaactgaa taatgccttt attcagtcgg agcgtaaaaa
     8581 aactcagcat caattggcag aacgccaaca aaaaaatcgt tttatgggtg caattctcat
     8641 tctagttatc tttcttttta tgttgcctgc ctataatctt gttgggactt acactaatat
     8701 tcagcagcag gaaaagaaac ttgctgaatt ggaaaaaaat tacgaagaac tgaccaaaga
     8761 acagaagcag gaagcagaga tggttgcaaa attgaaaaat gaggaatacg cagcaaagta
     8821 tgttcgggct aagtatcaat actctaaaga aggggaattt gtctacaata ttccagggtt
     8881 accaaaatga ccgaatctat ttttaaaatt gtagagcaat ttttacagca ttctgatgaa
     8941 aaattagaag agttgaatca aaagaataga gaattaaagt tagaagaaaa tgaatcgtag
     9001 aaaggaggga gtatgcagaa aaaactgctc gtatggttat tgccagtttt atttggatgg
     9061 caggtggtcg atagtacaga aataccattt gaactcacag cgcaagaaga atacgaattg
     9121 actcatacta tctatgatca gtattttcaa actatccctc aaaacccaaa tgtttttcaa
     9181 actgagaatc tttattcgga tgaagaattg actatagcag gtggacaatt acagccgaac
     9241 caacattttt ctattacgga tgttctagtc aatagcaaaa aagaattggt tttccaaata
     9301 gatgacaagg gttacattct tgcaagtagg catctactat ttgatgatgt aattgttaca
     9361 gaaactactg ttgagcaaac ttattggaca aaaaaaggtt tcacattgtt aacctcacca
     9421 attgctaacg aagctacgga aataaaaaat gatttacaac cctatcaagc tgttatggtt
     9481 tctaaaattg tgacaacttc cctaggtgat tttgcctatg ttacagataa aggttggatt
     9541 gcagtaaata atctttctaa aacggataat agagtagaag ccgttcaaga gttgttgact
     9601 aacaaatatt ccaaagatac tattggtata tatgtgaaac aattgtcaac aggtcaaact
     9661 gcaggtgtaa atcaagagaa actattctat tctgccagca ttgctaaact accaattctt
     9721 tattacgttc aagagcaact gaatgctgga tatattgatt tgactactaa agtgaaatat
     9781 acagccgaat ctatatcctt cccaggagct tatgttgctg gaggaagtgg ttcactgtca
     9841 aaaactcctg acaacaaaga ttattcagtg gaagaattga tcaataagac tgctaaagag
     9901 tcagataatg tagctagtaa tttactttct tattatgtag ctaataaatt cgattctaat
     9961 ttttatcaag taataactgc taaaacaggt agtgagtgga gtatggttac acgtgaaact
    10021 tcagctgaga ttgcagggaa aatgatggaa gccttatata ttcaaaatgg ctatgtgcta
    10081 gaaagtttgt tatctactca atttgataat caacgtattt cgaaagacat ctcagttcca
    10141 gttgctcata aaattggcga tgcagacgat gtcaaacacg atgtagcgat tgtttacgca
    10201 gggtctccct ttgttttatc tatttttaca gataaatcaa attatgatga gattacacaa
    10261 attgcaaatg atatttacag gattttaaag taaatgaaag atagattttt aaaagtgaca
    10321 ctggatggtc acttttttga taaacataag aaagtactag tagccgtatc tggtgggtta
    10381 gattctatga acctattcca tcttttatac gaatgcaaac aagtgttagg gattgaactt
    10441 ggaattgctc atattaatca tggacagaga gaagaatctg tcattgagga aaaatatctt
    10501 agacagttag cagaagaaag taatgttccc ttttatctgt cctattttga aggtgttttt
    10561 tcagaagaag cggcgcgaaa atggcgttat ggattttttg ctacaatcat ggagaaggaa
    10621 ggctacactg cactagtgac agcccaccat gcagatgatc aagcagaaac tgtctttatg
    10681 cgattgatta gaggcgggcg tttacgtcac ttatcagcaa ttcaaccgac tcagcctttt
    10741 gcaacagggg aacttattcg accactttta tcttttaaaa aggcagattt tgaaaagcta
    10801 tttcattttg aagattgcag caatgcagat ttcaaatatt ttcgaaatag agtcagaaat
    10861 gactatttac caaagttaaa acaggaaaat cctaaaatcg aacttactct caataatctt
    10921 gcagttgata caaataatct atttcaagcg ctaagagatt tgacacagga tttatccgtt
    10981 acagatgtga tgagttttca acaacagaca cctgcggtac aaagttatct attagaggaa
    11041 tatttggaaa aatttcctga tttacagctc tctcgtccac aatttaatga agtattacac
    11101 atcttgcgtt caaaagctaa ctactatcat ttattgaaaa atgattacat gctagaaaag
    11161 gattatcatc gttttcaaat ttataaaata ggaccagaga cggatagtca accagaaaaa
    11221 atcatgatag aatcagaggg gattttttct tacggttcat atattttttc tctcaatcat
    11281 cctttggaag aagcggatag tattttatat tttcctacag aaaatccaat tgtagtgagg
    11341 agaaggcagg ctggggatac cattttaata aacggagtaa ataaaaaact ccgccgttgg
    11401 tttattgata ataaaatctc acagaaagtt cgacaaaatg cgcttattat cgagcagaat
    11461 ggagaaattt atggaattac gaatcttgtt agcagtgatt tgagtaaatc agtaaaaaat
    11521 gatataatca aagctacctt atatataaaa atgaaagagt agaacaacta tgttggacaa
    11581 agatattaag aaaattcttg tttcagaaga agaaatcgtt gcaaaatgca aagaactcgg
    11641 tcaaattcta gcaacagact atgcagataa gaatcctatt cttgtaggaa ttttaaaagg
    11701 ttctatccca tttatggcag aattaatgaa acatattgat gcccatgtag aaacggatta
    11761 tatggttgtt tctagctacc atggcggaac ggagagttgt ggtaccgtta agattatcaa
    11821 ggatttggac aatagtgttg caggtcgata tatcatcttc gtagaggata ttattgacac
    11881 tggtcgcaca ttaaaagaat tgaaagaact ctttgctttg cgtcaggcag cttctattaa
    11941 aattgccact cttcttgata aaccagaagg tcgtgttgtt gaaatcgagc cagactacac
    12001 ttgctttact attccaaatg aatttgtagt tggatttggc ttagattatg atgaaaatta
    12061 tcgtaatctt ccttatgttg gtgtactcaa agaggaagtt tacacaaaat agaaaaaggt
    12121 ttcctactat attatgaaca atcaaccaaa taaaggattt ataaaaaatc cttttctcat
    12181 tattctcgtt attgccacta ttgttacagc ctttcaattt tttaacgctg gtcagcaagt
    12241 agcaactcaa gaaatcagtt attcacaagt agtaactgaa ttgaaaaata ataatgtatc
    12301 tgaaattact tatcaaccaa attcaagtgt tattgaaatt actggtaagt acaaaacaga
    12361 acaggaagct aaagatgagt tagcttcatc tattaagtta ttccaagttt ctagtaaagt
    12421 taagtataaa aactttaagt cgctaatttt accgtcagaa acgaatttgt cagagctaca
    12481 agctcttgca aatgaaaatg gagtaaaggt tgctattaaa cctgaaagtt ctaatggact
    12541 atggttgaac attatcttta atttgttgcc acttgttatt gctggtgtat tcttcatgat
    12601 gatgatgaac cagggtggtg gtggagcacg tggtgcaatg aactttggac ggaataaagc
    12661 taaagctttg gaacaaagta acatcaaggt acgtttctca gatgtagcag gtgcagagga
    12721 agaaaaacaa gaattagttg aagttgttga atttttgaag gatccaaaac gctttactaa
    12781 acttggagca cgtattccag caggtgtgct actagagggt cctccaggaa ccggtaaaac
    12841 cttgcttgcc aaagcagtag cgggtgaagc gggtgtacca ttcttctcca tttctggttc
    12901 agattttgtt gaaatgtttg ttggtgtcgg tgccagccgt gttcgttcat tatttgaaga
    12961 tgcaaaaaaa gcagcaccag ccattatttt catcgatgaa atcgatgctg tcggtcgcca
    13021 acgtggtgtc ggcatgggtg gcggtaacga tgaacgtgaa caaaccctca accaactctt
    13081 aattgaaatg gatggttttg aagggaacga agggattatt gtcattgccg caaccaaccg
    13141 tagtgatgtt ttagaccctg cccttcttcg tccaggtcgt tttgaccgta aggtattggt
    13201 tggtcgtccg gatgttaaag gacgtgaagc aatccttaaa gttcatgcga agaataaacc
    13261 actagcagca gatgtagatt tgaaattagt agcacaacaa acaccaggat ttgttggtgc
    13321 agatttagag aacgttctga acgaagcagc ccttgtagct gcacgtcgaa acaagactgt
    13381 cattgatgct tcagatattg acgaagcaga agatcgtgtt attgcaggtc catctaagaa
    13441 agaccgtcaa gtttcagcca aagaacgcga aatcgttgcc taccatgaag ctggtcatac
    13501 gattgtcggc cttgtcttgt caaatgcacg tgaagttcac aaagtaacaa ttgttccccg
    13561 cggtcgcgca ggtggataca tgattgccct tcctaaagaa gatcaaatgc ttctttctaa
    13621 agaagatatg aaggagcaat tggctgggct tatgggtggt cgtgttgcgg aagaaattat
    13681 ttttaataca cagaccacag gagcatcaaa cgacttcgag caagctacac agatggcgcg
    13741 tgctatggtt gctgaatatg gtatgagtga caaaatggga ccaatgcagt atgaaggcag
    13801 tcatgcaatg tttggtggac aaacaactca aaaacatatt tctgagcaaa ctgcatatga
    13861 gttagataat gaagtacgtg atttgttaaa tgaagctcgc aacaaagcgg ctgaaattat
    13921 tcagtctaat cgcgaaactc ataaactaat cgcagaagca ttacttaaat acgaaaccct
    13981 agacagtgtt cagatcaaat ctctctatga aacaggcaaa atgccagaga atattgaacg
    14041 tgatgatgaa gatgttcatc ccctttctta tgaagaggta aaagagaaaa ttaatacgaa
    14101 agagtagtat aaaaatactc ttggcaagac attccctcac tctcaaccac taaaataacc
    14161 acaaagcctt cgctaagtac ataatcttgg cgagggcttt tttacatgat acacatcaga
    14221 aacagggcat ttacaagaaa aacgaatcaa tagttattta tcacaatctt agaactatac
    14281 caaatcactc ccttcagaag cagaatgcaa tatttgccat agagtatcaa tagcaaatgt
    14341 actttaaaaa agaaaaatca aataaagtat gctagacaaa aatgtcctgt agaaagacag
    14401 cacttttcga taaacttaaa ccatcaacaa aaggagatta agtaatggaa ttcgaaaaag
    14461 tgtacgcaag cgtcaaaggt attgtaaaca aggctcgaaa agagttttac attaaactat
    14521 gggatcgaga tgattgggaa caagaaggaa tgatgacctt gtttgaattg ttggaagctc
    14581 aaccgtggct agttgatgaa caagttcaat tatattgtta ttttaaagtc aagttcagaa
    14641 atcgaatcaa agatcgtatc cgcaaacagg aaagtcaaaa acgcaagttt gaccgtatgc
    14701 cacatgaaga tatttacgaa ttatctcacg caatacaatc accgggattg ataaacgatg
    14761 aattattaat gttgagaggt gccttgagag attatcgaaa aaatctgagc aatgatcaac
    14821 ttgataaata cgaaaaatta attagcggac aatgttttaa tggtcgccgt gaaatgatac
    14881 gtgatttaca aattcatttg aaagactttc gctaaagcta gttactaaca tcacgttaat
    14941 cgaattaaga aattgggcag aagcaccata aaaagttctg ttcagtttct ttttagatag
    15001 gttatagcac aggaagaagg aataggagaa aaaacaaagt atctacatag aactttcagt
    15061 gtaaaaaat
//
LOCUS       DBNFCO010000048        14961 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.048, whole genome shotgun sequence.
ACCESSION   DBNFCO010000048 DBNFCO010000000
VERSION     DBNFCO010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 14961)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14961)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14961
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.048"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            14..1882
                     /locus_tag="AC1PIV_001310"
     CDS             14..1882
                     /locus_tag="AC1PIV_001310"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HIP6612331.1"
                     /translation="MTLVTNLKQHSHIITTALCLALILIGILLFQTGQGWAPILFISA
                     FVIGGYQSAKEGISELIFDKHLSVDLLMILAAIGSGLIGYWMEGALLIFIFSLSSTLE
                     ELAMKKSKNAIAALMNMTPPTARKIEENGDITVLDTAAIRIGDLLQVRKGDTVPLDAT
                     LISPQSIFDESMITGEPLPAEKMAGDAVIGGTINQGPTVTVQVTAEKGDALFDKIVQM
                     VENAQESKSKTATFIENMEDTYVKVVLVVVPLFILLAHFALGWDWLTAFYRGMILLTI
                     ASPCALVASSSPATLSAISRAARKGMIIKGGDIADNIANLEAIVFDKTGTLTIGKPEV
                     VGATYLGDEELIKQVVQAVEKQSSHPIAQALMTYTADSSAIALQSLEDVTGKGLVAGY
                     EGDSWKIGKAGFVADSLVSPLSAGLLAQIDEAESIGKTLVYVSQNDVLVAIFMVEDSL
                     KPESKQLIAQLKEMGVTPILLTGDQEKTARYVASQVGIDRVIANCLPTDKAAVIQELQ
                     TEFASVGMVGDGINDAPALAQANVSYAMGSGTDIAMESADIVLMEDLTRIPYSIRLSK
                     KMRGIIKQNIIFALSVIALLIISNLFQSINLPLGVVGHEGSTILVILNGLRLLYFK"
     gene            2017..2541
                     /locus_tag="AC1PIV_001311"
     CDS             2017..2541
                     /locus_tag="AC1PIV_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612332.1"
                     /translation="MKTNLLKTAGIVAACVRYFFYLLIASYIFFSLAGLGGDSFAIGS
                     WEYTFNKPIDQISVWLILLATGLILVVLVALSHIAHLIQKLCKLLLEEDYFASASMEL
                     YQKLFISLLVLTAGQFCLTSLITLTNAAGPNNFLNLRWSDFILNALFIFLTYFVWTLV
                     QKGQQLETENSEFI"
     gene            2543..2752
                     /locus_tag="AC1PIV_001312"
     CDS             2543..2752
                     /locus_tag="AC1PIV_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012774957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIP6612333.1"
                     /translation="MEMIRVNLDKVLKDRQMTSKDLAEQVGITEANLSILKTGKAKGI
                     RFNTLMSICRILDCQPGDILEYVEE"
     gene            complement(2876..3547)
                     /locus_tag="AC1PIV_001313"
     CDS             complement(2876..3547)
                     /locus_tag="AC1PIV_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HIP6612334.1"
                     /translation="MDINWQAVFNADIAREAIPQILEGLPYTLSLSLIGFALGTFCGF
                     FVALMRMSKFGPLRWLAMAHISLMRGIPLMVLLFFIYFGLPFMGLQLDAISASIIAFT
                     SMSSAYISEIIRASLSAIDKGQWEAARSLGLRTNVIHRKIIIPQAFRIALPPLSNVLL
                     DMVKSTSLTAMITVPEIFNKAKIVGGAKSDYMTVYICVALIYWVICTLYAFGQLKLEK
                     RLATY"
     gene            complement(3638..4513)
                     /locus_tag="AC1PIV_001314"
     CDS             complement(3638..4513)
                     /locus_tag="AC1PIV_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HIP6612335.1"
                     /translation="MLKKVLASALLVSTLTLAACSSSSSNTSSSSAEQTQWEKIQEAG
                     VLKVATPGTLFPTSYYNDAKELVGYEIDMINEIGKRLKLEIEYQEIGVAEAFTAVDSG
                     KVDISVNNFDMTEARKEKYNFSIPYKYSVGGYIVREDGSSGIEAADLSDWTGKKAGGG
                     AGTQYMKIAEKQGAEPVIYDNVTNDVYLRDVSTGRTDFIPNDYYTQVMAIKWANANFP
                     DIKVKMGEAKYNPTEQGIVMSKADTSLKEKIDEALEAMKADGTLKAISEKYYAGQDLT
                     VPVENADKLPVIEVE"
     gene            complement(4638..6086)
                     /locus_tag="AC1PIV_001315"
     CDS             complement(4638..6086)
                     /locus_tag="AC1PIV_001315"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HIP6612336.1"
                     /translation="MIWKDATAMAQAVNQKQVFAKELVQETIDRIEKLNPTLNAVVSK
                     QYEEALKEAEKEDYLGKPFAGVPFLLKDLGQNEKGQPSSAGSRLLAGRPAGHTDTYVQ
                     RLKDLGFIIVGRTNTPEFGFKNISDASLHGPVNLPLDPSRNAGGSSGGAAAALASGMV
                     SIAAASDGGGSIRIPASFNGLIGLKTSRGRIPVGPKSYRGWQGASVNFALTKSVRDTQ
                     RLLYHFQDYQLEAPFPLAKLSEEEVFGKLSRPLKIAYYTKSPVGSKVSLEAVEAVQKA
                     CHHLANLGHEVVELTEYPLDGVALMKSFYLMNSVDTAQMFDEIEAAFGRQMTLDDMEV
                     MSWAIYQSGQTIPAKLYSKALLDWDQFGASMARFHEEYDLLLTPTVADVAPKHGQFDL
                     PVDLLDRLKQTQNYSMEEQQDLIWQMFEDSLALTPFTQQANICGQPAISLPTYVRADS
                     LPIGVQLTASKGREDLLLQLADQMEAAGLLNL"
     gene            complement(6096..6923)
                     /locus_tag="AC1PIV_001316"
     CDS             complement(6096..6923)
                     /locus_tag="AC1PIV_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HIP6612337.1"
                     /translation="MKSWVENVTIKKYEDRSGLTGLKQEPLVWTEVFLREVNRQSNTG
                     ILHFWPMDQTVILGMMDSQVAQLDKGLASIGQAGYSPIIRSLGGLAVVADEGILNVTL
                     ILSNPSGHKVDLRESYQVMVDLIAQALSDFPFEVVSGEVATSYCPGTYDLSIKGRKFA
                     GLAQRIYQEAIAISAYISVSGNQVKRGQVVADFYVASFAPQEVSDRFPQVNPDSMANL
                     SDLVGQDVTVEDMKKRIEQVLVENGTRLSTFYPSSDNMADFMTFGKTIKQSMEKYGI"
     gene            complement(7199..8335)
                     /gene="dnaJ"
                     /locus_tag="AC1PIV_001317"
     CDS             complement(7199..8335)
                     /gene="dnaJ"
                     /locus_tag="AC1PIV_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HIP6612338.1"
                     /translation="MNNTEFYDRLGVSKNASPDEIKKAYRKLSKKYHPDINKDPGAED
                     KYKEVQEAYETLSDPQKRSAYDQYGPAGANGGFGGGAGGFGGFDGAGFGGFEDIFSSF
                     FGGGGATRNPNAPRQGDDLQYAVNLKFEEAIFGVEREVSYNREATCRTCTGSGAKPGT
                     SPVTCGRCHGSGVINVDTQTPLGTMRRQMTCDVCHGRGKQIKDPCTTCHGTGHEKQAH
                     TVTVKVPAGVETGQRIRLAGQGEAGFNGGPYGDLYVVIQVQPSDKFEREGTTIHYKLN
                     LNFVQAALGDTVHVPTVHGDVDMVIPEGTQTGKTFRLKGKGAPSVRGGAIGDQYVTVN
                     IVTPTGLNDRQKAALKEFAAAGNIDVKPHKKGFFDKVKDAFEDL"
     gene            complement(8767..10590)
                     /gene="dnaK"
                     /locus_tag="AC1PIV_001318"
     CDS             complement(8767..10590)
                     /gene="dnaK"
                     /locus_tag="AC1PIV_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HIP6612339.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTIISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     EYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     DEKILVFDLGGGTFDVSILELGDGVFDVLATAGDNKLGGDDFDQKIIDHMVAEFKKEN
                     GIDLSADKMALQRLKDAAEKAKKDLSGVTSTQISLPFITAGAAGPLHLEMTLTRAKFD
                     ELTYDLVERTKIPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRND
                     VDQAIFATEKTLKETEGKGFDAERDQAQAALDELKAAQEANNLDDMKAKLENLNEKAQ
                     ALAVKLYEQAAAAQQAAAGQEGAQTANNADDDVVDGEFTEK"
     gene            complement(10687..11199)
                     /gene="grpE"
                     /locus_tag="AC1PIV_001319"
     CDS             complement(10687..11199)
                     /gene="grpE"
                     /locus_tag="AC1PIV_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HIP6612340.1"
                     /translation="MSEEIKNEEIVEEVEATEEVVETPEKSELDLANERAEEFENKYL
                     RAHAEMQNIQRRANEERQTIQRYRSQDLAKKILPSLDNLERALQVEGLTEDVKKGLEM
                     VQESLIQALKEEGVEEVATDVFDPNLHMAIQTVPATDDCPAEHIAQVFQKGYKLHERL
                     LRPAMVVVSE"
     gene            complement(11212..12246)
                     /gene="hrcA"
                     /locus_tag="AC1PIV_001320"
     CDS             complement(11212..12246)
                     /gene="hrcA"
                     /locus_tag="AC1PIV_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HIP6612341.1"
                     /translation="MITQRQNDILNLIVELFTRHHEPVGSKALQEMIASSSATIRNDM
                     AKLEQLGLLEKAHTSSGRMPSRAGFQYFVNHSLNLKHINEEDVYQVVKAFDFEAFKLE
                     DILERASQVLADLTGYTSVILDVEPTSQQLTSFDIVQLSSHDALAVLTLDQSKPVTVQ
                     FAIPKNFLTRDLEVLKRLVDERFVGQTVLAIHYKLRTEIPQVVQRYFATTDNVLDLMD
                     YIFSNLFQESVFISGKVASLTYGNLATYQLLDSPQLLAPELRQGLAPNQQTSISVAEH
                     REPALADVTVIHHRFPIPYRGMGQMSLLGPVDMDYRRQMSLINIISRILFMKLTDYYR
                     YLSSNHYEVN"
     gene            complement(12565..13260)
                     /locus_tag="AC1PIV_001321"
     CDS             complement(12565..13260)
                     /locus_tag="AC1PIV_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HIP6612342.1"
                     /translation="MADVRLYISRHGKTMFNTIGRVQGWCDTPLTKVGEEGIRELGLG
                     LKDAGLDFKLAVSSDLGRTVQTMTIAQRELGILGKIPYYQDKRIREWCFGSFEGMYDA
                     ELFQGVLPRLKGTVDATGMSFAEIAAGIQEADTAGWAESWEVLSNRILTGFESIAQDL
                     EKQGGGNALVVSHGMTIATLAHLLEPERGANVFLDNGSITVLKYENGKLLIEAVGDLS
                     YRKRGAELIAQGK"
     gene            complement(13336..14673)
                     /locus_tag="AC1PIV_001322"
     CDS             complement(13336..14673)
                     /locus_tag="AC1PIV_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HIP6612343.1"
                     /translation="MDIRQVRETIEMIEEQNFDIRTITMGISLLDCIDSDIDKAAEKV
                     YTKIVTKAKNLVAVGDEIAAELGIPIVNKRVSVTPIALIGAATDATDYLPLAHALDKA
                     AHEIGIDFIGGFSALAQKGYQKGDEILINSIPQALAQTSKVCSSVNIGSTKTGINMTA
                     VRDMGRIIKETAEASDMGAAKLVVFANAVEDNPFMAGAFHGVGEADVVINVGVSGPGV
                     VKRALEKVRGESFDVVAETVKKTAFKITRIGQLVGNMASERLGVKFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDAVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPETTPAETIAAMIADEAAIGVINQKT
                     TAVRIIPLGKEGDMIEFGGLLGTAPVMKVNQASSVDFINRGGQIPAPIHSFKN"
     gene            complement(14685..14951)
                     /locus_tag="AC1PIV_001323"
     CDS             complement(14685..14951)
                     /locus_tag="AC1PIV_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HIP6612344.1"
                     /translation="MKAIVTVVGKDKSGIVAGVATKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKKDFTKLRAELEAYGQALNVKINIQSAAIFDAMHNL"
BASE COUNT         3941 a         3654 c         3217 g         4149 t
ORIGIN      
        1 ggaagagcaa actatgacac tcgtaaccaa cctcaaacaa cacagccaca tcatcacgac
       61 cgctctttgc ttggcgctca ttctaatagg tatccttctg tttcagactg gacagggatg
      121 ggctcctatc ctcttcattt cagcctttgt catcgggggc taccaatcag ccaaggaagg
      181 catttctgag ctgattttcg acaagcacct gtctgtcgac ctgctcatga ttttagctgc
      241 tatcggctct ggtctaattg gctactggat ggagggggct ctactcatct tcatcttctc
      301 cctttcttct actctggaag aattagccat gaaaaaaagc aagaatgcga tcgctgcttt
      361 gatgaacatg acccctccaa cagctcgcaa aatcgaggaa aatggtgaca ttactgtctt
      421 agacaccgca gccatccgca ttggcgacct cctgcaagtc cgcaagggtg acacggttcc
      481 actggatgct accctcatca gtccgcaatc catctttgac gaatccatga ttacaggcga
      541 gccgctccct gcggagaaaa tggctggcga tgctgttatc ggcggaacca ttaaccaagg
      601 tccaactgtg accgtacaag ttacggctga aaaaggcgat gccctcttcg ataaaatcgt
      661 ccagatggtt gaaaacgccc aagaatccaa atcaaaaaca gcgactttca ttgaaaatat
      721 ggaagatacc tatgtcaagg ttgtcttggt ggtggtacca ctcttcatcc tccttgctca
      781 ttttgcactg ggctgggact ggttaactgc cttctaccga ggcatgattc tcttaaccat
      841 cgcttctcct tgtgccctcg tagcttcttc ttcacccgca acactttctg ccatcagccg
      901 tgcggcacgt aagggcatga ttatcaaggg cggtgacatt gcggacaaca tcgccaatct
      961 agaggccatc gtctttgata agacgggtac cctgaccatt ggtaaacctg aagttgtagg
     1021 tgcgacctat cttggcgatg aagagcttat caagcaggtt gttcaggcag ttgaaaaaca
     1081 atcaagccac ccaatcgctc aggctctcat gacctatacg gctgacagct ctgctattgc
     1141 ccttcaaagc ctagaagacg tgacaggaaa aggcttggtg gcaggctatg agggcgacag
     1201 ctggaaaatc ggtaaggcgg gatttgtggc ggacagcctg gtgagtcccc tgtctgctgg
     1261 cttgctggca cagatcgatg aggcggaaag cattgggaaa accctggtct atgtcagcca
     1321 aaatgatgtg ctggtggcga tcttcatggt ggaagatagt ttgaaacctg agagcaagca
     1381 gctgattgcc cagttgaaag aaatgggcgt gacgccaatt ctcttgacgg gtgaccaaga
     1441 aaagacggct cgttacgtgg cgagtcaggt cggtattgac cgtgtgattg ccaactgtct
     1501 gccgacggat aaggctgctg ttatccaaga attacaaacc gagtttgcgt ctgtcggcat
     1561 ggtcggagac ggcatcaacg acgctcccgc cctggctcaa gccaatgtca gctatgctat
     1621 gggaagcgga acggacatcg ctatggagtc agctgacatc gtactcatgg aagacctgac
     1681 gagaattcct tactccattc gtctctctaa gaaaatgcgg ggcatcatca agcagaacat
     1741 catctttgcg ctatctgtca ttgcccttct tatcatctcc aacctcttcc agtctatcaa
     1801 cctcccactc ggtgtggtgg gccacgaagg atcaacgatt ttggtgattt tgaatgggtt
     1861 gagactattg tattttaaat agcttcaaac cgccaggtag ttggcggttt tcttattatt
     1921 ctttttttaa aaaaacgctt gcatttcaaa aattattgtt ttataataat tttacagata
     1981 atattatcat aaaacaataa taatcggagg tttgctatga aaaccaatct actcaaaaca
     2041 gctggcattg tggctgcttg tgttcgctat ttcttctatt tattaattgc aagctatatt
     2101 ttctttagcc tggctggtct tggaggcgac tcctttgcga taggctcttg ggaatacacc
     2161 tttaacaaac ccattgacca gatcagtgtc tggctcattc tgctagcgac tggattgatt
     2221 ctagttgtct tagtagcact cagtcacatt gcccacttga ttcaaaagtt atgtaaattg
     2281 cttctggaag aagattattt cgcttcagct agtatggaac tttatcagaa gctcttcatc
     2341 agtttgctcg tcctgactgc tgggcaattt tgcctaacca gcttgatcac cttgacaaat
     2401 gctgctggac caaacaactt cctcaatctg cgttggtcag atttcatcct caacgccctc
     2461 tttatcttct tgacttattt tgtctggacc ttagtacaaa aggggcaaca acttgaaacc
     2521 gagaacagcg agtttatctg atatggaaat gattcgcgta aacttagaca aggtcctcaa
     2581 agaccgacaa atgacttcca aggacttggc ggagcaagtc ggcatcaccg aagccaatct
     2641 gtccattctc aagacaggca aggcaaaagg cattcgtttt aataccctga tgagcatctg
     2701 ccgcatctta gactgccaac caggggatat tttggaatat gtggaagagt gagagttaca
     2761 tcgaaaaaac agtctttaaa ataaaaaata gcttaggtcc acatcattcg agacgttaat
     2821 tctaagctat ttttgattgt tcaaatttta atcggaaggc taaaccaacc tctttttagt
     2881 aagtcgccaa gcgtttttct agcttgagct gaccaaatgc ataaagggta cagataaccc
     2941 aataaatgag ggctacacag atataaaccg tcatataatc cgacttagct ccaccgacta
     3001 tttttgcctt attgaaaatc tctggtacag taatcatagc ggtcaaggac gtacttttca
     3061 ccatatccaa gagaacattg ctcagtggtg gaagagcaat ccgaaaggct tggggaataa
     3121 tgatttttct gtgaatcaca ttggtccgca agcccaggga acgcgctgcc tcccattgtc
     3181 ccttatcaat ggccgaaaga gatgcacgaa taatttcaga aatgtaggca ctggacatgg
     3241 aggtaaaggc gataatagat gcggagatag catctagttg tagccccatg aaaggcaatc
     3301 caaaatagat gaaaaagaga agaaccatga ggggaattcc acgcatgaga gaaatatggg
     3361 ccatagccaa ccaacgcaag ggtccaaact tagacatccg catgagggct acaaaaaatc
     3421 cacagaaagt ccccaaggca aaaccaatta gggataggga tagagtgtag ggaagtccct
     3481 ccaaaatctg tggaatagcc tctcttgcaa tatctgcatt aaaaactgcc tgccagttaa
     3541 tatccatatc ttctcctctt tcctaaaaac cagatagacc ttgccagtct gtgactgaca
     3601 aagtctatac aagatgcatt taatttgtta cgaggtctta ttcaacttcg ataactggca
     3661 atttatcagc attttcaaca gggactgtca agtcttgtcc tgcatagtat ttctcagaaa
     3721 ttgccttcaa agttccatca gctttcatcg cttcaagtgc ttcgtcaatt ttttctttca
     3781 agcttgtgtc agccttgctc ataacaatac cttgttcagt tgggttgtat ttagcctcac
     3841 ccatttttac cttgatgtct gggaagttgg catttgccca tttgatagcc atcacttgtg
     3901 tatagtaatc atttggaatg aagtctgtac gacctgtaga tacatcacgc aaatagacat
     3961 cgttggttac attgtcatag ataactggct ctgcaccttg cttttcagcg attttcatgt
     4021 actgagtacc agcgccacca ccagctttct tgccagtcca gtcgctcaag tcagctgctt
     4081 cgattcctga tgaaccatct tcacgaacaa tgtagccacc aactgaatac ttgtaaggga
     4141 tagagaagtt gtacttttcc ttacgtgctt ctgtcatgtc aaagttgtta acagaaatat
     4201 ctaccttacc actgtcaacc gctgtaaagg cttctgccac accgatttct tggtattcaa
     4261 tttccagttt caaacgctta ccaatttcat tgatcatgtc aatttcatat ccgaccaatt
     4321 ctttagcatc attgtagtaa gaagttggga agagggtacc tggtgtagca actttcaaga
     4381 caccagcttc ttgaattttt tcccattgag tctgttcagc agaagaactg ctagtattcg
     4441 aacttgaact agaacatgct gccaaggtca atgtagaaac caagagagct gaggctaaaa
     4501 cttttttcaa cataaaacaa tctcctttgg aagccatagc ttcctttttt actttttcgg
     4561 tgttaaccca ccaactttta caggttaaca ttttgaaaac gttttggcaa ataattgaac
     4621 tgaaaaaatg aattccctta caagttgagt aaaccagctg cctccatttg atctgccaac
     4681 tgcaagagca aatcctctcg tcccttggat gctgtcaatt gaacgccgat tggcaggctg
     4741 tcagcacgta cataagttgg cagagaaata gctggctgac cacaaatatt ggcctgctgc
     4801 gtaaagggag ttaaggccag actgtcctcg aacatttgcc agatcaggtc ctgctgctct
     4861 tccatggaat agttctgggt ctgcttgagg cgatccagca aatctactgg taggtcaaat
     4921 tgtccatgct tgggcgctac atcagccact gtcggcgtca ggagcaagtc gtattcctca
     4981 tggaaacgcg ccatgctggc tccaaactgg tcccagtcca atagggcctt ggagtacaat
     5041 ttggctggaa tagtttgccc gctttggtaa atagcccagg acatgacttc catgtcatcc
     5101 aaggtcatct ggcgcccaaa agctgcttcg atttcgtcaa acatctgggc cgtgtccacg
     5161 ctgttcatca ggtagaagga tttcatcagg gccactccat ccagaggata ttctgttaat
     5221 tccaccactt catgccccaa atttgccaag tgatgacagg ctttttgaac cgcttctacc
     5281 gcttcaagac tgaccttgct ccctactgga gatttggtat agtaggcgat ttttaggggg
     5341 cgagacaatt ttccaaaaac ctcctcttca ctcagcttgg caaggggaaa aggagcttcc
     5401 agctggtagt cctgaaaatg atagagcaga cgctgggtgt cacggacaga cttggtcagg
     5461 gcaaaattga cagatgctcc ctgccagcca cgataagact taggtccaac tggaatccga
     5521 ccacgactgg ttttgagccc gatcaagcca ttgaaggagg ctgggatgcg aatagaccca
     5581 ccaccatccg atgctgcagc aatagagacc atgcctgaag ccagtgctgc agctgcacca
     5641 ccacttgatc caccagcatt gcgactgggg tccaagggaa gattgacagg accatgcagg
     5701 ctggcgtctg agatattttt gaagccgaat tctggcgtat tggttcgacc gactatgatg
     5761 aaacccaaat ctttcaagcg ttggacatag gtgtcggtat ggcctgctgg tcgaccagca
     5821 agtaggcgag aaccagcaga agatggctgc cccttttcat tttgccccag atccttcaac
     5881 aagaaaggaa ctccagcaaa tggcttgccc agatagtctt ctttctccgc ttctttcaag
     5941 gcttcttcat actgcttgct gacaaccgca ttgagggtgg gattgagctt ttcaatcctg
     6001 tcaatcgttt cttgcaccaa ttccttggca aaaacctgtt tttgattgac agcctgagcc
     6061 atggctgtcg catctttcca tatcataaga atctcctaga taccatattt ttccatagac
     6121 tgcttgatgg tctttccaaa ggtcataaaa tcagccatgt tgtccgacga gggataaaaa
     6181 gtagacagcc tggtcccatt ttcaaccaat acttgctcaa tccgtttctt catatcctcc
     6241 accgtcacat cctgaccgac caagtctgac agattggcca tcgaatccgg atttacttgc
     6301 ggaaatctgt ccgatacttc ttgcggagca aaacttgcca cataaaaatc cgccaccact
     6361 tgcccacgtt tgacttgatt acctgacaca ctgatatagg cagaaatggc aatagcctct
     6421 tggtaaatcc gctgggccaa tccagcaaac ttccgcccct tgatactaag gtcgtaggtc
     6481 cctggacagt aggaagttgc cacctcacca ctgacaacct caaagggaaa atctgaaagt
     6541 gcctgggcaa tcaaatccac catgacctga taagactccc gcaaatcaac cttgtgacca
     6601 gaaggattgg acaaaatcag agtgacattt aaaatccctt catctgcaac gactgccaaa
     6661 ccgcccaaac tccgaataat aggactgtag cctgcctgac caatactggc taagcccttg
     6721 tccagctggg caacctgact atccatcatc cccagaatga ccgtttggtc catgggccaa
     6781 aaatgtaaaa ttcctgtatt ggactgacga ttgacctcgc gcaaaaagac ctcagtccac
     6841 accagtggct cctgtttcaa acccgtcaag ccagaccgat cttcgtattt ctttatggtc
     6901 acattctcaa cccaagattt cattcgtaag cgttctcttt caaattacta tatcttattt
     6961 taacacagag cctgtgatgc gtcggagaaa atgcccagag ttttttctga aaaagaaagg
     7021 ggagtgggaa agaactcgac caagataaaa agagttcgtc ttcccacccc cgcacagttg
     7081 attaggccag atttggagtg caaaacacga acaaatctgc caatcaacca ctgcgctgag
     7141 atgttgaaac gaactctgag tagtggtcct gggctttttg cccagtctca tcttagaatt
     7201 ataaatcctc aaaggcatct tttaccttgt caaaaaatcc ttttttatgg ggtttgacat
     7261 caatatttcc agctgccgca aattctttaa gagctgcttt ttggcggtca ttcaaacctg
     7321 tcggagtgac gatatttact gtgacatatt gatcaccaat agctccacca cgaacacttg
     7381 gtgcaccttt tcctttgagt cggaaggtct taccagtctg ggtaccttca ggaatgacca
     7441 tatccacatc accgtgaact gttggcacat gaacagtatc tccaagtgct gcttggacaa
     7501 agttgaggtt cagtttatag tgaatggtgg tcccttcacg ttcaaacttg tctgaaggtt
     7561 ggacctgaat gacaacgtag agatctccgt atggacctcc attgaaacca gcttcacctt
     7621 gaccagccaa gcgaatacgt tgaccagttt ccacaccagc tggcacctta accgttaccg
     7681 tatgggcttg tttttcatga ccagttccat gacaggttgt acatgggtct ttgatttgtt
     7741 ttccgcgacc atgacagaca tcacaggtca tttgacgacg catggttcca agtggagttt
     7801 gggtgtccac attgatcact ccagaaccat gacaacgccc acaggttacc ggacttgttc
     7861 caggtttggc acctgaacct gtacaggttc gacaagttgc ttcacgattg taggaaactt
     7921 ctcgttccac accaaaaatc gcttcttcaa atttcaaatt gaccgcatat tgcaaatcat
     7981 ccccttgacg aggtgcatta ggattgcgcg tcgcaccacc tccaccaaag aaactagaga
     8041 aaatgtcttc aaagccaccg aaacctgctc cgtcgaaacc accaaagcca cctgctcctc
     8101 cgccgaagcc tccattagca ccagcaggac catactggtc ataggcagac cgtttttgcg
     8161 ggtcgctcaa ggtctcataa gcctcctgga cctccttgta tttatcctcc gcacccggat
     8221 ccttgttaat atctggatgg tatttctttg aaagcttccg ataagccttc ttaatctcgt
     8281 ctggcgaagc attcttagaa acaccaagac gatcgtaaaa ttcagtattg ttcatataag
     8341 ataccaagcc cgttaaaagc aaagtgaaaa taggaaatcg gcagaaaatc ctgattttct
     8401 agacgattta tctttttcac acagctttta gggcgagttc atttcctttc gttaaataat
     8461 agacgaaact cagaaagtag cccgtgttca gttacgaaca ctttcctttc tgtaaaagtt
     8521 agacgggtat ttacccaaaa acagaggctg ggttgcaacc tctgtgattg gaatctttat
     8581 taactaataa tttctattct cgggaagagg agaactgagt tcaagctaag aactacggaa
     8641 aaaagataac tttccttgtt ctagatactc aaagaaattc aagactaggc taggcaactg
     8701 gacgaagatt gaactggagt tcatcgagga gagttaacga agcctagtga agaatttcga
     8761 agagtactac ttttcagtaa actcgccatc taccacatca tcatctgcat tgttagctgt
     8821 ttgggcacct tcttggcctg cggctgcttg ttgtgctgct gcggcttgct cgtagagttt
     8881 cactgcaagg gcttgggctt tttcgttgag gttttcaagt ttagccttca tgtcgtccaa
     8941 gttgttagct tcctgagctg ctttcaactc atcaagagca gcttgggctt ggtcacgttc
     9001 tgcgtcgaag cctttgcctt ctgtttcctt aagagttttc tcagtcgcaa agattgcttg
     9061 gtcaacatcg ttacgaaggt ccacttcttc cttacgtttc ttatctgctt ccgcgttagc
     9121 ttctgcatct ttcatcatgc ggtcgatttc ttcatctgtc aaacctgagt tagactggat
     9181 aacgatagtt tgttcttttt gtgtaccaag gtctttggct tttacagaaa cgataccgtt
     9241 cttgtcgatg tcgaatgtta cttcgatttg tggaatacca cgaggtgctg cagggatgtc
     9301 tgtcaattgg aaacgaccaa gagtcttgtt gtccgctgcc attggacgct caccttgaag
     9361 cacgtggatg tcaacagctg gctggttgtc cgctgcagtt gagaaaactt gtgatttaga
     9421 agttgggatt gttgtgttac ggtcgatgag ttttgtaaat acaccaccca ttgtttcgat
     9481 accaagtgac aatggtgtta cgtcaagaag aacaacatct ttgacatcac cagtaatcac
     9541 accaccttgg attgccgcac ccatggcaac cacttcgtca gggtttacag atttgtttgg
     9601 ctctttacca gtttcagctt ttacagcttc cacaacggct gggatacgag ttgaaccacc
     9661 gacaaggatt acttcatcga tttctgatag gctgagacct gcatctgaaa gggcttgacg
     9721 aacaggaatt tttgtacgtt ctacaaggtc gtaagtcaat tcgtcaaatt tcgcacgagt
     9781 caatgtcatt tccaagtgaa gtggacctgc tgcacctgca gtgatgaatg gcaagctgat
     9841 ttgagttgaa gtcacgcctg acaagtcttt cttagctttt tcagctgcat ctttcaaacg
     9901 ttgaagggcc attttgtcag ctgacaagtc gataccgttt tctttcttga actctgctac
     9961 catgtggtcg ataatctttt ggtcaaagtc gtcaccaccg agcttgttat cacctgctgt
    10021 tgcaagtacg tcaaagacac cgtcaccaag ttcaaggata gatacgtcga atgtaccgcc
    10081 accaaggtcg aataccaaga ttttttcatc tttgtcagtc ttgtccaaac cgtaagcaag
    10141 agctgctgca gttggttcat tgacgatacg ttctacttca agaccagcga ttttaccagc
    10201 gtctttggtt gcttgacgtt gggcatcgtt gaagtaagca ggaacagtga taaccgcttt
    10261 ggttactttt tcaccaagat attcttcagc gtaacctttc aagtattgaa gaatcattgc
    10321 tgagatttct tgtggtgtgt attctttacc gtttgctgaa actttttcag aagttcccat
    10381 ttttgatttg atagagatga tggtatctgg gttggttacc gcttggcgtt ttgccgcgtc
    10441 accaacgatg atttcaccat ttttgaaaga cacaacagac ggagttgtgc ggtttccttc
    10501 tgggtttgca atgatttttg attcagttcc ttcaagaact gcaactgctg agtttgttgt
    10561 acctaagtca ataccgataa ttttagacat atgtgttacc tctttttaat ttacttttta
    10621 tgttcaattt agcctagttt aatgacattt cggtcaggtt ttcttttttg ggaaatagca
    10681 gagcgactat tccgacacca ctaccatagc cggtctcagc aagcgttcat gcagcttgta
    10741 gcctttttgg aagacttgtg cgatgtgttc tgctgggcaa tcgtctgtgg ctgggactgt
    10801 ttgaatggcc atgtgaagat ttgggtcaaa gacatctgtt gcgacttctt ccaccccttc
    10861 ttctttaagg gcttgaatca agctttcttg aaccatttcc aagccttttt tgacatcttc
    10921 tgtcaagcct tcgacttgaa gggcacgttc caagttatcc aagctcggca agattttctt
    10981 ggccaagtct tgcgaacggt aacgctgaat ggtttggcgt tcttcgtttg cacggcgttg
    11041 gatattttgc atttcagcgt gggcacgaag gtacttgttt tcaaattcct cagcgcgctc
    11101 gtttgccaaa tccaattctg atttttcagg tgtctccaca acttcttctg ttgcttcaac
    11161 ctcttctacg atttcttcgt ttttgatttc ttctgacaaa gcattctcct tctaattgac
    11221 ttcgtaatga ttactactta gataacggta gtaatcggtt aatttcataa ataggatgcg
    11281 gctgatgatg ttgattaagc tcatctgcct acggtagtcc atgtcaacag gaccgagcaa
    11341 actcatctgg cccatgcccc gataggggat tggaaaacga tgatgaatga ccgtcacatc
    11401 tgcaagagca ggttctctat gttccgccac ggaaatgctg gtctgctggt tgggagccaa
    11461 gccctgccgc aactctggtg ccaataactg aggactatcc aagagttggt aggtggcaag
    11521 attgccgtag gtcagcgagg caacttttcc actgataaag accgattctt ggaaaagatt
    11581 ggaaaagatg tagtccatga gatccaagac attgtccgtc gtggcaaagt aacgctgcac
    11641 cacttgggga atctccgtcc gcaacttgta gtggattgcc aagaccgtct gcccaacgaa
    11701 gcgctcatca actaagcgtt tgagcacttc caaatcccta gtcaagaagt tcttaggaat
    11761 agcaaactga acagtgacag gtttggactg gtccagagtc aagactgcca gagcatcgtg
    11821 gctactgagc tgcacaatgt caaaggaagt cagctgctga ctggtcggct ccacatctaa
    11881 aatgaccgag gtgtagcctg tcaaatccgc taggacctga cttgctcgct ccaagatgtc
    11941 ctctagcttg aaggcttcaa agtcaaaggc cttaaccact tgataaacat cttcttcatt
    12001 gatgtgtttc agattgagcg agtggttgac aaagtattga aaaccagccc gactgggcat
    12061 acgaccactt gatgtgtggg ccttttccag caaacccaac tgctctagct tggccatgtc
    12121 attacgaatg gtagccgaac ttgaagcaat catttcctgc aaggccttag aaccaactgg
    12181 ctcatgatgg cgcgtaaata attcaacaat cagattcaaa atatcatttt gacgttgggt
    12241 aatcatctcc gctcctttca tgaacactgt tttagttacg ctcagcgaaa atcgacagta
    12301 gcctaggaag cgaggccgaa tgtagaacta tggttcacaa aggcaagctg acaacggata
    12361 gtgttgattt ttgaagagcg ttagcactct atgatatcga gtgctaatta cttatactcc
    12421 cattatacgc cgaaaaaatg gattgtcaag agaaaaagac aaaaaattag cactcttttg
    12481 cttagagtgc taaaaatcag tctgaggacc tagaatggtg gatgtcaaga aaaaaaatca
    12541 gagaatcctc cctgatttta tatcttattt cccttgggca atcaactctg ccccacgttt
    12601 gcggtaggat aaatccccaa ctgcttcaat taaaagcttg ccattttcgt atttgaggac
    12661 ggtgattgag ccgttatcga gaaagacatt ggcaccacgc tctggctcta acaaatgagc
    12721 caatgtcgca atagtcatac cgtggctgac cacaagggca ttgcctccgc cttgtttttc
    12781 caagtcctgg gcgatggatt caaaacctgt caagatacgg ttgctcaaaa cctcccacga
    12841 ttccgcccag ccagcggtgt ctgcttcttg gatacctgct gcgatttccg caaaggacat
    12901 acccgtcgca tcaactgtcc ctttcaaacg aggcaggacc ccttggaaaa gctcggcatc
    12961 gtacatgcct tcaaaactac cgaaacacca ttcacggata cgcttgtctt ggtaataagg
    13021 gattttccct aaaattccta actcacgctg ggcgatggtc atggtctgaa cggttcgacc
    13081 cagatcactg gatacggcta gtttaaagtc aaggcccgca tccttgagcc ccaagcccag
    13141 ttcacgaatt ccttcctcac cgaccttggt cagcggcgta tcacaccagc cctgcacgcg
    13201 cccaatggta ttgaacatgg ttttcccgtg acgagaaata tataatctta catctgccat
    13261 tcgtttttct ccttgtcatt tcttactatt agtataacaa aaaaccgact gcttgtggca
    13321 atcggtctac gttttttagt tcttaaagct atgaatcggt gctggaatct gaccaccacg
    13381 gttgataaag tccacagacg aagcttgatt gaccttcata acaggagctg ttcccagaag
    13441 gccgccaaat tcaatcatgt ctccttcttt tccaagcgga ataatacgaa ccgcagttgt
    13501 tttctgattg ataaccccaa tagccgcttc atccgcaatc atagccgcaa tggtttcagc
    13561 aggcgttgtt tctggaatgg caatcatgtc caaacctaca gaacagatag ccgtcatggc
    13621 ttccaatttt tcaaggttga gcgagccatt ttgcaccgcc gcaatcatgc cctcatcctc
    13681 agacacaggg ataaaggcac ctgacaagcc accgacttgg ttgcaggcca tgaccccacc
    13741 ctttttgact gcgtcattga gcaaagccag ggcagcagtc gttccgtgcg taccaacggt
    13801 ttctaagccc atttcctcca aaacccgtgc tactgagtcg ccaacagctg gtgttggagc
    13861 aagcgacagg tccacgatac cgaacttaac ccccaggcgt tcactggcca tattgccgac
    13921 caactgaccg atacgggtaa tcttgaaagc cgtcttcttg acggtctccg ccaccacatc
    13981 aaagctctca ccacgcactt tttcaagggc acgcttgacc acaccaggcc cagacacgcc
    14041 gacattgatg accacatccg cctcgccgac accgtggaag gcccccgcca tgaaaggatt
    14101 gtcctcaacc gcattggcaa agaccaccaa cttggcagcc cccatatcag aagcctccgc
    14161 cgtctcctta atgatccgcc ccatgtcccg cacagccgtc atattgatac ccgtcttggt
    14221 cgagccgata ttgactgacg agcagacctt agaggtttgg gccaatgcct gcggaataga
    14281 gttgatgagg atttcatcac ctttttggta gcccttttga gcaagagctg aaaaaccacc
    14341 gataaaatcg atgccgatct catgagccgc cttgtccaag gcatgagcta ggggaaggta
    14401 atccgtggca tccgtcgccg caccaatcaa agcaataggc gttactgaca cccgtttgtt
    14461 gacaatggga atgcctagtt ctgccgcaat ctcatcgccg actgctacca agttcttggc
    14521 cttggtgaca atcttggtat acactttctc cgcagccttg tcgatatccg agtcgataca
    14581 gtccaagagg gaaatcccca tggtgatggt ccgaatatcg aaattctgct cctcaatcat
    14641 ttcaatggtt tctctaacct gtctaatatc catgaaatct ctccttacaa gttgtgcata
    14701 gcatcaaaaa tggctgcact ttgaatgttg attttcacat tcaaagcctg accataggct
    14761 tctagttctg cacgaagctt ggtgaaatct ttcttctcat ctgacgacac caccgccatc
    14821 atggtaaaat actcatccaa aacagtttgt gaaatatcat cgatattgag ccctaactcc
    14881 gcaatcttgg tcgcaacacc cgcaacaatt cctgacttgt ccttaccgac aactgtaaca
    14941 atagctttca tctgaacacc t
//
LOCUS       DBNFCO010000049        14650 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.049, whole genome shotgun sequence.
ACCESSION   DBNFCO010000049 DBNFCO010000000
VERSION     DBNFCO010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 14650)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14650)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14650
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.049"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            137..1969
                     /gene="lepA"
                     /locus_tag="AC1PIV_001324"
     CDS             137..1969
                     /gene="lepA"
                     /locus_tag="AC1PIV_001324"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HIP6612345.1"
                     /translation="MNLEDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPIINKIDLPAADPERVRQEIEDVI
                     GLDASEAVPTSAKAGIGIEEILEQIVEKVPAPTGDVEAPLQALIFDSVYDPYRGVILQ
                     VRIVNGVVKPGDTIQMMSNGKTFDVTEVGIFTPKAIGRDYLATGDVGYIAASIKTVAD
                     TRVGDTVTLAENPASEPLAGYKQMNPMVFAGIYPIDSNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERIEREFNIDLIMTAPSVVYHVNMTDGEMID
                     VANPSEFPDPTKIATIEEPYVKAQIMVPQEYVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYEISEYRSSKLVKMDILLNGDKVDALSFI
                     VHKEFAYERGKIIVDKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDEDDKK"
     gene            complement(2019..2201)
                     /locus_tag="AC1PIV_001325"
     CDS             complement(2019..2201)
                     /locus_tag="AC1PIV_001325"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001117229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HIP6612346.1"
                     /translation="MPFVRIDLFEGRTEEQKIALAREVTEVVSRNTNAPKEAIHVFIN
                     DMPEGTYYPQGEMKRK"
     gene            2336..3643
                     /locus_tag="AC1PIV_001326"
     CDS             2336..3643
                     /locus_tag="AC1PIV_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excalibur calcium-binding domain-containing
                     protein"
                     /protein_id="HIP6612347.1"
                     /translation="MFKKKATQIVSETSIKKSRKFLNRKTAGITGGVLLTTFIGSQLM
                     TAELPKKDDLYGQQYVTVVKHLQEAGLKNIQGVEITDLEFGKIGESNLVELVSVDGED
                     WKEGRTLKNIPITISYHVPKKDAVEFNLPASKNLADVEKELKDSGFMQIELTPVLLVE
                     EGNADKKDKIDRLQIGNHTYQSNHFYSTSLPVTLTYFDVSKDNIKLPENLAEAKTKLE
                     LEKQLKTAGFTDIKWTAVADKDKAKHEKIQKINLGGAEIQLPTKQEIISKKSTPIVIT
                     YYDFSSFAELPSSISTKTAADTKKLFTDGGFSQVSEVATETNEIAKNGQIIAVEIDGK
                     SFNEMNDKVIKKDSKVIVKYWNAEKAIAEKARKEEEERLAAEAQKVAEAQSQVQQFTA
                     TPSQNTYYPNCKAVRQAGAAPIYHGEPGYGSHLDRDGDGVGCE"
     gene            4028..4609
                     /locus_tag="AC1PIV_001327"
     CDS             4028..4609
                     /locus_tag="AC1PIV_001327"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004797 - thymidine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HIP6612348.1"
                     /translation="MAQLYYKYGTMNSGKTIEILKVAHNYEEQGKPVVIMTSALDTRD
                     AFGVVSSRIGMRRDAVAIDDDMDIFGFIEKMEPRPYCVLIDEAQFLRRHHVYALARVV
                     DELDVPVMAFGLKNDFRNELFEGSQHLLLLADKLDEIKTICQYCSKKATMVLRTQDGK
                     PTYEGEQIQIGGNETYIPVCRKHYFSPEIKDLP"
     gene            5060..6139
                     /gene="prfA"
                     /locus_tag="AC1PIV_001328"
     CDS             5060..6139
                     /gene="prfA"
                     /locus_tag="AC1PIV_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001028822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HIP6612349.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEATTR
                     DTVTAYREYKTVLQNIVDAEEMIKESSGDADLEEMAKEELKQAKADKEAYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEGQGWRFEVMEASYNGVGG
                     IKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLIMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKMDEVVDALVLYDQTQKLEELNK"
     gene            6139..6972
                     /gene="prmC"
                     /locus_tag="AC1PIV_001329"
     CDS             6139..6972
                     /gene="prmC"
                     /locus_tag="AC1PIV_001329"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002934985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HIP6612350.1"
                     /translation="MNYAQLFAAYEEQLVAIGEEAESLSFTFRGLKGLNFTEFLLLLR
                     QEVTPTDKEEIDAIFQQLSQHRPAQYIIGKADFHGLEFAVDERVLIPRPETEELVDLI
                     LQENSGASLRILDIGTGSGAIAISLAKARPDWEVVAVDISNDALAVAQENARTNQVSV
                     HFLESDVLQAVTGKFDIIVSNPPYISPDDTDEVGLNVLTSEPHLALFAEEDGMAIYRQ
                     IAEQAGAFLKENGKLYFEIGYKQGQDLTDLLALHFPQKQIRVLKDQFGQDRKVVADDN
                     G"
     gene            6959..7567
                     /locus_tag="AC1PIV_001330"
     CDS             6959..7567
                     /locus_tag="AC1PIV_001330"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HIP6612351.1"
                     /translation="MTMDKLRTILENGGAVILPTETVYGLFAQALNEDAVNRVYQLKQ
                     RPRDKAMNLNVSNLNDIYFFSQNTPFFLEKLYNRFMPGPLTIILKANDNVPFWVNSGL
                     DTVGFRLPNHEQTLRLISETGPLIGPSANISGNESGKKFSDIQAQFSVDLPGIEDDQA
                     LTGIDSTILDLSGQKARILRQGAISREEIQKAIPEIEFEVVL"
     gene            7564..7995
                     /locus_tag="AC1PIV_001331"
     CDS             7564..7995
                     /locus_tag="AC1PIV_001331"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIP6612352.1"
                     /translation="MIRPIEKSDLIVIREINAQSLGYDCSLEQTERQFFRCTSTLGHI
                     LLVYIDDISGAVQGYIHAQVYESLYSDTGLNILGLAVLPGHQGQGIGASLLKAVEQIA
                     QKEGYHFIRLNSAESRLQAHLFYEKNGYHSDKMQKRFIKHI"
     gene            8019..9278
                     /gene="glyA"
                     /locus_tag="AC1PIV_001332"
     CDS             8019..9278
                     /gene="glyA"
                     /locus_tag="AC1PIV_001332"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HIP6612353.1"
                     /translation="MIFDKVNYKEFDKEVWEAIQAEEKRQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTECVDVVESLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMALIEPGDTVMGMDLAAGGHLTHGASVSFSGQTYNFVAYNVDEETGLLDYDAIL
                     KQAKEVQPKLIVAGASAYARTIDFAKFREIADAVGAKLMVDMAHIAGLVAAGLHPNPV
                     PHAHITTTTTHKTLRGPRGGLILTNDEELIKKINSAIFPGIQGGPLEHVIAAKAVSFK
                     EVLDPAFKDYAQKVIENSKAMAEVFLANPNFKVITGGTDNHLFLVDVTKVVENGKVAQ
                     HLLDEVNITLNKNSIPYEKLSPFKTSGIRIGSAAITARGFGVEEARKVAQLTIKALEN
                     AENEKALEEVRQEVRALTDQFPLYEGL"
     gene            9278..10252
                     /locus_tag="AC1PIV_001333"
     CDS             9278..10252
                     /locus_tag="AC1PIV_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HIP6612354.1"
                     /translation="MDIFVKKAIIHQFSPDDTELVLSDQLLTVSPKIEEYLRKKIERV
                     FSDEAKTGQFNPDNPFLDYLDGDLLTNSVKIANLWKEEFSISENLKTNDLIFIEFERN
                     GVEHFAFLRISLRENLAHVGLESGSPLKITQNNLPGAGSAPDEALIVNLQTRKYHLIE
                     KRIKHNGAFLNYFSDNLLQVTPAISAKKSIKAVEQTAQKIADNFHQGDFQFQSKVKSA
                     IFNNLEEDNELSPEKLADQLFDNNLTARLNFVDQLKEVIPDKISFDEIDSSRQLKKFE
                     NQKLSLSNGIELIVPNAIYEDAESVEFIQNDNGTYSILIKNIEDIKSK"
     gene            10253..10852
                     /locus_tag="AC1PIV_001334"
     CDS             10253..10852
                     /locus_tag="AC1PIV_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HIP6612355.1"
                     /translation="MKKLIRTLILLLLIFLGYKFYQTYNAVKQVMTYQTMVQEVLAEN
                     DTPANEELVLAMIYTETKGQEADVMQSSESATGYANTITDSRESIRQGIIYLTENLRL
                     AEEKGVEVWTAVQAYNFGPAYIDYIAEHGGEHTLSLAKEYSRTVVAPSLGNTTEETYT
                     YFHPLALLNGGKLYVNGGNIYYARQVRFNMHLMRLINLF"
     gene            10953..11711
                     /locus_tag="AC1PIV_001335"
     CDS             10953..11711
                     /locus_tag="AC1PIV_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002934991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HIP6612356.1"
                     /translation="MKRNVLITGASSGIGKAIAYVFAANGDNIIITGRRLDKLEEIKQ
                     DIEKQYHVQVSVHSFDVTNMEQTIVNCQKILEEVGQIHILVNNAGLALGLDKFQDYDL
                     TDMMTMIDTNIKGLLTVTRQLLPQMVENNEGHIINIGSTAGIYAYAGAAVYAATKSAV
                     KVLSDGIRIDTIDKNIKVTTLQPGIVETDFSQVRFHGDKERAATVYQGIDALQANDIA
                     SCTLFVANQPAHVQISDMTIMATKQATGFTIHRD"
     gene            11728..12477
                     /locus_tag="AC1PIV_001336"
     CDS             11728..12477
                     /locus_tag="AC1PIV_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6287 domain-containing protein"
                     /protein_id="HIP6612357.1"
                     /translation="MKRKYLALALGLLTIMSLSACQTEKKGSSASTSTADTQVSNANT
                     SRSSTIQREISLSSMDIDALMQGNYDSILGTWQNSQGNSLVFNSKGLVADSQSLLGRG
                     KITDGIFETGYVDATIGDVTLLMIPKGTQANTTETDTTDSTRDRMIVISQETTADVVD
                     VYYRLTNSATSGIDPLKNTETGVQLDSGPKTIDYANSILGENNWRVIEGNYTRTESIP
                     YNILEGDDNARYTIYQNGVIINADYQIVYQP"
     gene            12499..12852
                     /locus_tag="AC1PIV_001337"
     CDS             12499..12852
                     /locus_tag="AC1PIV_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002943204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIRAN domain-containing protein"
                     /protein_id="HIP6612358.1"
                     /translation="MTFTSFEPTRNVQDFHLAAFAYYDGLDVIDQLKPGTPVQLVGEP
                     SNPHDSEAVAIFYQGTKLGYIPSDKNSLISRLIYFGHGDILEARIQMSNTENHPDRQF
                     RVVVKLKDNRKNDSR"
     gene            complement(12873..13820)
                     /locus_tag="AC1PIV_001338"
     CDS             complement(12873..13820)
                     /locus_tag="AC1PIV_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612359.1"
                     /translation="MDVFPSFFISMFNELNIFVDLKNIFCYTCVMKTSTLGKLLELPN
                     FHHFYTVPIRENTESSGNYIIVFEQDKQPVFVDLKNETGHTREVRFASHFDSAGLLVG
                     LGAIPINYWSTCQILGVKKNNNRRGLSLSSLMDGYRRLPIFKEMAERYRARGQSTIYD
                     PYRYSYTIDEKKVIKDNQLTLIPKKEYEKIKDFHPFLQTKHGNVYAVPCFYQDRKRNQ
                     ITKIYIMGWYFYEKQLKISWKPSHSRKSRWRSSLVSVDKLSDRFFFQGELYKKGTYPV
                     FLEDLTIKNKAYQHRLDREFAAFLSIIEEQKQRAQLRVK"
     gene            complement(13848..14636)
                     /locus_tag="AC1PIV_001339"
     CDS             complement(13848..14636)
                     /locus_tag="AC1PIV_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002943206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612360.1"
                     /translation="MAVLKYSKVLLLVLLIATGLSCIGIYWLGKEQNRLLNEQCHALN
                     IRIINDLGTKIDAIGGPQNPRIIGFFQQDDTTAISQRIGTASEEELKIAKPDNLFQKE
                     WIVLYPQTRSSPFENASAYAVMKTSIKADWLHVTTSSETELDIFYEKADESLLTLEDL
                     VQDKESFRATLKTILVSAKNEAEIQVQKDILEMFESDDWSAIPFAYTEKSLILEKAVI
                     SISAFVDSLNPYYFSEQTLADLRLSEESRQALEDSVDKTIITYP"
BASE COUNT         4658 a         2907 c         3013 g         4072 t
ORIGIN      
        1 cttattttat gaccgactag aacttacttt gggaatttac tcgtaacaat aacctatatt
       61 tctaggtgtt tttcttatgg aaaattatca ctaaatctga tataatgagg agtaataccc
      121 ttgtagagga agaaacatga atttagaaga tttgaaaaaa cgacaggaga aaattcgtaa
      181 tttctccatt attgcccaca tcgaccatgg taaatcaacc ttggctgacc gtattcttga
      241 gaagacggaa acagtttcca gccgtgaaat gcaagcccag ttgctggata gtatggactt
      301 ggaacgcgag cgtggtatca caattaaact caacgcaatc gaactcaact atacagctaa
      361 agatggagag acatacattt tccacttgat tgacacacca ggacacgtgg attttaccta
      421 tgaggtatcg cgttcgttgg ctgcctgtga aggagcgatt ttagtggtgg atgctgctca
      481 agggattgaa gcacagacct tggccaacgt ttatctagcc ttggacaatg atttggaaat
      541 cttgccaatc attaacaaga ttgacctgcc agcagcagac ccagaacgtg ttcgtcagga
      601 aatcgaagat gtgattggtt tggatgcttc tgaagcagtg ccaacatcag ccaaggcagg
      661 tattggtatc gaggaaatct tggagcagat tgtcgagaag gttccagcac cgactggtga
      721 tgtcgaagct ccattgcaag ccttgatttt tgactcggtt tacgatccgt atcgaggcgt
      781 tatcctccaa gttcgtatcg tcaatggtgt ggtaaaacct ggtgacacca ttcagatgat
      841 gagcaatggt aagactttcg atgtgacgga agtggggatt ttcacaccca aagcaatcgg
      901 tcgtgattat ttggcgactg gtgatgttgg ttacattgca gcctctatca agaccgttgc
      961 agatacccgt gtcggtgata cggtaacctt ggcagaaaat cctgccagcg agccactagc
     1021 gggctacaag cagatgaatc caatggtctt tgcaggtatc tatccaatcg attccaacaa
     1081 gtacaatgac ctccgtgaag ccttggaaaa actccaactc aacgatgcca gcttgcagtt
     1141 tgagccagaa acatcgcagg cactcggatt tggtttccgt tgtggattct tgggcctctt
     1201 gcacatggat gttatccaag aacggattga gcgtgagttt aacattgacc tcatcatgac
     1261 agcaccgtcg gtggtttacc atgtcaacat gacggacggt gaaatgattg atgtagccaa
     1321 cccatccgaa ttcccagacc caacaaagat tgccactatc gaagagcctt acgttaaggc
     1381 acaaatcatg gtaccacagg aatacgtcgg tgcagtcatg gaattggccc aacgcaaacg
     1441 cggtgacttt gtgactatgg attacatcga tgataatcgt gtcaatgtca tctaccaaat
     1501 tccacttgcg gagattgttt ttgacttctt tgataagctt aagtcgtcca ctcgtggtta
     1561 tgccagcttc gactatgaga tttctgaata ccgttcatcc aagttggtga aaatggatat
     1621 tctcctcaat ggtgacaagg tcgatgccct cagctttatc gtccacaagg aatttgccta
     1681 cgaacgtggg aaaattatcg tggacaaact caagaaaatc attccccgtc aacagtttga
     1741 agtaccaata caagcagcta tcggtcagaa aattgttgcc cgtagcgaca tcaaggctct
     1801 tcggaagaac gttttggcca agtgttatgg tggtgacgtt tcccgtaaac gcaaactcct
     1861 agaaaagcaa aaagctggta aaaaacggat gaaagccatc ggctctgtcg aagttccaca
     1921 agaagccttc ctcagtgttc tcagcatgga tgaagacgat aagaaataaa cttgatacaa
     1981 agaaacactc ctgcattttc ttgcaagagt gttttctctt atttacgttt catttcacct
     2041 tgtgggtagt aggtcccttc aggcatatca ttgatgaaga catgaatggc ttctttgggc
     2101 gcattagtat tgcgtgatac cacctcagtt acttcacgcg caagggcaat tttttgttct
     2161 tctgtgcgtc cttcaaacaa atcaatacgt acaaatggca tatatttcct cctttatttt
     2221 tcgtttattg taccatagtt tttatgattc tccaaggata ttttcataag atataacaaa
     2281 atatatttat attttgttat aataatatcg cgacaaacaa taaggagaat gatttatgtt
     2341 taagaaaaaa gcaactcaga tagttagcga aacgtcaatt aaaaaatcta gaaaatttct
     2401 taatcggaaa acagcaggaa taactggtgg cgtcctactt acaacattta tcggttcaca
     2461 attaatgact gctgaacttc caaaaaaaga tgacctttat ggacaacagt atgtaacagt
     2521 cgtaaaacat cttcaggaag caggtttaaa aaatattcag ggggtggaaa tcactgattt
     2581 agaatttgga aaaataggtg aaagcaatct tgtcgaactc gtctctgttg acggagaaga
     2641 ttggaaggaa ggacgtactt taaaaaacat cccaattaca atctcctacc atgttcccaa
     2701 aaaagatgcc gttgaattca acctaccagc ttctaaaaat ttagcagatg tcgagaaaga
     2761 gctgaaagat tcaggtttta tgcaaatcga actaactcct gttctgctag tagaagaagg
     2821 caatgcggac aaaaaagata aaattgatcg ccttcaaatc ggaaatcaca cctatcaatc
     2881 caatcatttt tactctacta gtctccctgt tacattaacc tattttgacg ttagcaaaga
     2941 taacatcaaa ctaccagaaa atctagcaga ggctaaaaca aaactagagc tcgaaaaaca
     3001 actaaaaaca gcaggattta cagacatcaa gtggactgct gttgcagaca aggataaagc
     3061 aaagcacgaa aaaattcaaa aaattaatct aggtggtgca gagattcaat tgcccaccaa
     3121 acaggagatt atcagcaaaa aatcaacccc cattgtaatt acctactacg atttctctag
     3181 cttcgctgaa ctgccatcat ccatttcaac gaaaacagct gcagatacta aaaaattgtt
     3241 taccgacggt ggtttttctc aagtatctga agtagcaaca gagaccaatg aaattgctaa
     3301 aaacggacaa atcattgcgg tcgagattga tggaaaatct tttaacgaga tgaacgataa
     3361 ggtcatcaaa aaagatagca aagtcattgt caaatattgg aatgctgaaa aagctattgc
     3421 tgagaaagca cgtaaagagg aggaagaacg tctcgccgcc gaagcgcaaa aagtagcaga
     3481 agcacaaagc caagttcagc aatttactgc tacaccatct caaaacacat attatccaaa
     3541 ttgtaaggca gttagacaag caggagctgc accaatctat catggagaac caggttacgg
     3601 tagtcattta gaccgtgatg gagatggagt tgggtgtgag taagaaaaaa cattgacaac
     3661 gtttacattg cgtgctatac tactcttata aggagggatt gctcatgacc tataaatacc
     3721 gtatgatttt atcgttccta ctcactggat tatttttgta tctagtagta actgttttta
     3781 acaaaagtgt atgggaaggc ccattgtttc ttgcattttc tttttacagc ctgatatatg
     3841 gttgtgttat gctctacaag tggaaaccaa cggcagctaa aatcattttc cgatgtattg
     3901 gagaatttct ctctttacca tggtcttaat atcaaacaag ctcaaaacgg gcttgttttt
     3961 ctatttccta aatggtcaat ttatgataga atggagggag tgaaaattta agattggaaa
     4021 gagaaaagtg gctcaattat attataaata tgggacaatg aactcaggaa aaaccattga
     4081 gattttgaag gttgcccaca actatgaaga acaaggaaaa cctgttgtta tcatgacatc
     4141 tgcacttgat actcgtgatg cctttggtgt tgtatccagt cgtataggca tgagaagaga
     4201 tgcagtggcg attgacgatg atatggatat ctttggtttt attgaaaaaa tggaaccgcg
     4261 tccttactgt gttctcattg atgaagcaca atttcttcga cgtcatcacg tctacgcact
     4321 tgctcgcgta gtcgatgaat tagatgtacc cgttatggct ttcggtctta aaaatgattt
     4381 ccgaaatgaa ctatttgaag gttcccaaca tttgctctta ttggctgata aattagatga
     4441 aatcaaaaca atctgccaat attgttctaa aaaagcgaca atggttttga gaacacagga
     4501 tggaaaacct acttatgaag gagaacaaat ccaaattggt ggcaatgaaa cctacattcc
     4561 tgtctgtcgc aaacattatt tttcaccaga aattaaagat ttaccctaat ttttgaaaat
     4621 gaaatgagaa gcaactgtaa actgagcaac tatatagaac tgaatttgcc tatgactctg
     4681 tgccaatttt cataacttac atactacggc aaaggaattg aacacgccct acaagctgtg
     4741 tcaaaaagat aatttctcca agtgtttgta acacttggtc aaaattccta ttttgactgt
     4801 gcttgcttaa cgggctttgt atcttaatgg aattgaacac gccctacaag ctaactagaa
     4861 gtgtgtgcgg tcaaatattt agaaaggaat tgaatacggg ctacgaactg tgcctgtttc
     4921 atgacctaca tattacagaa aggaattgaa cacgccctac aagctgtgtc aaaaagataa
     4981 tttctccgag tgtttgtaac acttggtcga aattcctatt ttgactgtgc ttgcttaacg
     5041 ggctttgtat cttaatctta tgaacatcta cgatcaatta caggcggtgg aagaccgcta
     5101 cgaggaactt ggtgaattgt tgtctgaccc tgatgtagtc agcgatacca agcgttttat
     5161 ggagttgtct aaggaagaag ctacaactcg tgatacagta acagcctacc gcgaatataa
     5221 gactgtactt caaaacattg tcgatgcaga agagatgatt aaagaatctt ctggtgatgc
     5281 tgacttggag gaaatggcta aggaagaact caaacaagct aaggctgata aagaagctta
     5341 cgaagaaaag ctgaaaatcc ttcttttacc aaaagaccct aacgatgaca aaaacatcat
     5401 cttggaaatc cgtggtgccg caggtggtga tgaagctgcc ctctttgctg gagacctttt
     5461 gaccatgtat caaaaatatg cagaaggtca aggctggcgt tttgaggtta tggaggcttc
     5521 atataacggt gtcggcggta tcaaggaagt ggttgccatg gtctctggtc aatccgttta
     5581 ttcaaaactc aagtatgaat caggagctca ccgtgtccaa cgtgtccctg tgacagaaag
     5641 ccaaggtcgt gtccacacct cgacagcaac tgtcctcatc atgccagaag ttgaagaagt
     5701 ggaatacgac atcgatccaa aagatcttcg tgtcgatatt taccacgcat ctggtgctgg
     5761 tggacagaac gtcaataagg ttgcgactgc cgttcgtatc gttcacttgc caaccaacat
     5821 caaggtcgaa atgcaggaag aacggactca gcagaaaaac cgtgaaaagg ccatgaagat
     5881 tatccgtgcc cgtgttgcgg atcactttgc acagattgcc caagatgagc aggatgctga
     5941 gcgtaaatca actatcggta caggtgaccg ctcagagcgc atccgtacat acaacttccc
     6001 acaaaaccgt gtgacagacc accgtatcgg cttaaccttg caaaagctgg atactatctt
     6061 gtcaggtaag atggacgaag tcgtagatgc ccttgttctc tacgatcaaa cgcaaaaact
     6121 agaagagctt aacaaataat gaattacgct caattatttg cagcatacga agaacaatta
     6181 gtcgcaatcg gtgaagaggc agaatccctg tccttcacct ttcgtggctt aaagggattg
     6241 aactttacgg aatttctcct cctgctccgt caggaagtca caccgactga caaagaagag
     6301 attgatgcga tttttcagca actttcccaa caccgacctg cccagtacat tatcggcaaa
     6361 gctgattttc atggcttgga gtttgcggtg gatgagcgag tcttgattcc aagacctgaa
     6421 acggaagaat tagttgattt gattttgcag gaaaatagcg gagcaagttt gcgtatctta
     6481 gacatcggta caggaagcgg tgccatagct atttcccttg caaaagctag acctgattgg
     6541 gaagtggtag cggttgacat ttcaaatgat gccctagcag tggctcagga aaatgcaaga
     6601 accaaccaag tctctgttca ctttctagaa tcggatgtct tgcaagctgt gacagggaaa
     6661 tttgacatca ttgtttctaa tccgccctat atctcaccag atgacacaga tgaagttgga
     6721 ctcaatgtat tgacttctga gcctcatctt gccttatttg cggaagaaga tggcatggct
     6781 atctatagac aaattgcgga gcaagcaggg gcatttttga aggaaaatgg aaaactctac
     6841 tttgaaattg gctacaagca agggcaagac ctaaccgact tactcgctct gcatttcccc
     6901 caaaagcaaa ttcgagtcct caaagaccaa tttggacagg atagaaaggt cgtagcggat
     6961 gacaatggat aaactccgaa caattcttga aaatggtggt gctgttatcc ttccaactga
     7021 aacagtctat gggctttttg cccaagcctt gaatgaagat gcagtcaatc gtgtctatca
     7081 gttgaaacag cgtccgcggg acaaggcaat gaacttaaat gtctcaaatc tgaacgatat
     7141 ttattttttc agtcaaaata cacccttttt tctggagaaa ctgtataata gatttatgcc
     7201 aggaccgcta acgattatcc tgaaagcaaa cgacaacgtt cctttttggg ttaattctgg
     7261 actggatact gttggttttc gtcttcctaa tcacgaacaa accttacgtt tgatttcaga
     7321 gactggccca cttattggac cgtccgccaa tatttcagga aacgaaagtg gcaagaagtt
     7381 ttcggacatc caggcacaat tttcagttga tttgcctggc attgaggatg accaagctct
     7441 aacaggcatt gattcaacga ttttggacct ttctggacag aaagcgcgga ttttgcgcca
     7501 aggtgctatc agccgcgaag agattcagaa agccattccc gaaatagaat ttgaggtagt
     7561 tttatgattc gtcccattga gaaaagtgac ttgatagtca tccgagaaat caatgctcaa
     7621 tccttagggt atgattgttc attggaacaa actgagcgac agttttttag atgcacgagc
     7681 acattggggc atatcttgtt ggtctatata gatgacataa gtggcgcagt gcaaggttac
     7741 attcacgcac aagtctatga aagtctctat tcggatacag gcctcaatat tctcggacta
     7801 gctgttttgc ctggtcatca aggacaaggg attggagcaa gcctgctgaa agccgttgag
     7861 caaattgcac agaaagaggg ctaccatttt attcgcctca attctgctga aagtcgtctc
     7921 caagcccatc ttttctacga aaagaatggc tatcactccg ataaaatgca gaagcgtttt
     7981 atcaagcaca tttagcccaa tacaaaggag taccgtatat gatttttgac aaagttaact
     8041 acaaagaatt tgataaagaa gtttgggaag ctatccaagc tgaagaaaaa cgccaacaaa
     8101 ataatatcga attgattgcg tctgaaaacg ttgtttctaa agctgttatg gcagctcaag
     8161 gttctatttt gaccaataaa tacgcagaag gttacccagg tcgtcgttac tatggcggta
     8221 cggaatgcgt tgacgtagtt gaaagtttag ctattgaacg tgctaaagaa atattcggtg
     8281 caaaatttgc taacgttcag ccgcactcag gaagccaggc caattgtgct gcctacatgg
     8341 ccttgattga gccaggagac actgttatgg ggatggactt agctgcaggt ggtcacttga
     8401 ctcacggtgc atcagttagc ttctcaggac aaacttacaa ctttgtagct tacaatgttg
     8461 acgaagaaac tggcttgctt gattacgatg caattttaaa acaagcaaaa gaagtacagc
     8521 caaaattgat tgtagcaggt gcttcagcct atgcccgtac aattgacttt gctaaattcc
     8581 gcgaaattgc agatgcagtg ggggccaaac tgatggtgga tatggctcat attgctggtc
     8641 ttgtagcagc aggtcttcat ccgaacccag tgccacatgc ccatattaca acaactacga
     8701 ctcataaaac tcttcgtggg ccacgtggtg gtttaatttt gaccaatgat gaagagctca
     8761 tcaagaaaat caactcagcc atcttcccag gcatccaagg tggtccatta gagcatgtca
     8821 ttgctgcaaa agccgtatct ttcaaagaag ttttggaccc agctttcaaa gactatgctc
     8881 agaaagtgat tgagaacagc aaggccatgg ccgaagtctt ccttgcaaac cctaacttta
     8941 aagtcatcac aggaggaaca gacaaccatc tcttcctcgt tgacgtgacc aaagttgttg
     9001 aaaatggtaa agttgctcag catctcttgg atgaagtaaa tattactctc aataaaaact
     9061 caattcctta cgaaaaactc tcaccattca aaacaagcgg tatccgtatt ggctctgcgg
     9121 ccattactgc tcgtggtttt ggagtagagg aagctcgcaa ggttgcacaa ctaactatca
     9181 aagcacttga aaatgcagaa aatgaaaaag ctcttgagga agtccgtcaa gaagtgcgtg
     9241 ctttgacaga tcaattccca ctttacgaag gtttataatg gatatatttg taaaaaaagc
     9301 catcatacat caatttagtc ctgatgatac agagctggtc ctttccgacc agcttttgac
     9361 tgttagccca aaaatagaag aatatttgcg taaaaagatt gaacgtgtct tttctgatga
     9421 agcaaaaaca ggacaattta accccgacaa tccttttctt gactatttag atggcgacct
     9481 actgaccaac tctgtcaaga ttgctaatct atggaaagaa gaattttcaa tttctgagaa
     9541 tttaaaaacc aatgacctca ttttcataga gtttgaacga aatggtgttg aacattttgc
     9601 ctttttgaga atctcactgc gtgaaaatct cgcccacgtt ggtctggaaa gcggaagtcc
     9661 tttaaaaatc acccagaata atttacctgg agcaggttca gcacctgatg aagccttgat
     9721 tgtcaatctt caaacgcgga agtatcattt gattgagaaa agaatcaaac acaatggagc
     9781 cttcctcaat tatttctcag ataatcttct gcaagttaca ccagctattt ctgcaaaaaa
     9841 atcaatcaaa gcagtagagc aaactgcaca gaagattgct gacaatttcc atcaaggcga
     9901 ttttcaattt caatcgaaag tcaagtcagc tattttcaac aatttggaag aagataatga
     9961 gctttcacct gaaaaattgg ctgatcagtt attcgataac aacctgaccg ctcgtttaaa
    10021 tttcgtcgat caactgaaag aggtcatacc tgataagatt tccttcgatg aaattgatag
    10081 tagccgtcaa cttaagaaat ttgaaaatca gaagctatct ttatcaaacg gaattgagtt
    10141 gattgtgcca aatgcaatct atgaggatgc agaatcggtt gagtttattc aaaatgacaa
    10201 cgggacctat tctattctta tcaaaaatat tgaagacata aagagcaagt aaatgaaaaa
    10261 actgatacgt acgctgatac ttcttttgct gatttttctc ggttacaaat tctatcaaac
    10321 ctacaatgca gtcaagcaag tgatgaccta tcaaactatg gtacaagaag tattggctga
    10381 aaacgacaca ccagctaatg aagaactagt cctagcaatg atttacacag aaaccaaggg
    10441 acaagaagca gatgtcatgc aatcgagtga gtccgctact ggctatgcta acactatcac
    10501 ggatagtaga gagagtatca ggcaaggaat tatctacctg acagaaaacc tacggttggc
    10561 tgaggaaaaa ggagtagagg tttggacagc agttcaggca tataatttcg gtccagccta
    10621 tattgactat attgctgaac atggtggaga acatacactc tctttagcta aagaatactc
    10681 cagaacagta gtagcaccaa gcttagggaa tactacagaa gaaacatata cctattttca
    10741 tcccttggct ttgctaaatg gtgggaagtt atatgtaaat ggtggaaata tctactatgc
    10801 tagacaggtt cgttttaata tgcacctgat gcgcctcatt aatttatttt aatacctatc
    10861 aaactcatcg gaaatctgat gagtttttaa ctacagcatt tttacaaact aggtaaaatt
    10921 gtagtataat aaagagaata ggagacagag tgatgaaacg aaatgtattg attacaggtg
    10981 caagtagtgg tattggcaaa gcaatcgctt atgtgtttgc tgctaatggt gataatatca
    11041 tcattacagg acgaagattg gacaaactag aagaaattaa gcaagatatt gaaaagcaat
    11101 accatgttca ggtgtcagtt cattcatttg atgttacgaa tatggaacaa acgattgtaa
    11161 attgtcaaaa aattttagaa gaagttggtc aaattcatat tttggtaaac aatgctggcc
    11221 tggcattggg attggacaaa ttccaagact atgatttgac tgacatgatg acaatgattg
    11281 ataccaatat taaaggatta ctaactgtga cacgtcagtt attgccacaa atggttgaaa
    11341 ataatgaggg tcatattatc aatattggat caacggccgg tatttacgcc tatgcaggag
    11401 ctgctgtcta tgctgcaacc aaatcagctg tcaaagtgct ttcagacggg atccgtattg
    11461 acacgattga taaaaatatc aaggtaacta cgttacaacc cggtatcgtt gagactgatt
    11521 ttagccaagt ccgttttcat ggagataaag agagagcagc gacagtctat caaggaattg
    11581 atgctcttca agcaaatgat attgccagct gtactctatt tgttgcaaat caacctgcac
    11641 atgtgcagat ttctgatatg accattatgg caaccaaaca ggcaactggc tttactattc
    11701 atagagatta gaggggagat agctagaatg aaaagaaaat atttagcact cgctcttggc
    11761 ttgctcacta tcatgtcgct ttctgcctgt caaactgaaa agaagggcag ttccgcaagt
    11821 acctcaactg ctgataccca ggtttctaat gccaatacaa gcaggtcatc aacaatccaa
    11881 cgtgagattt ctcttagttc tatggatata gatgctctaa tgcaaggcaa ttacgatagt
    11941 atactaggca cctggcaaaa tagccaagga aattcactag tcttcaatag caaaggatta
    12001 gtagcagata gccagtcctt acttggccgc ggaaaaataa ctgacggaat ttttgaaaca
    12061 ggctatgtag acgcaacgat tggcgatgta acactattaa tgattcccaa aggaacacaa
    12121 gcaaatacaa ctgagacaga cactactgac tctacgcgcg atagaatgat tgtaataagc
    12181 caagaaacaa cagcagacgt ggtagatgtc tattatcgct tgaccaattc agccactagc
    12241 ggtatagacc cattaaaaaa tactgaaaca ggcgtccagt tggatagtgg accaaaaacg
    12301 attgattatg ccaactcaat tttaggcgaa aacaattggc gcgtcattga aggtaactac
    12361 acgcgcaccg aatctattcc ttataatatt ttggaaggcg atgataatgc ccgttacact
    12421 atttaccaaa acggtgttat tatcaatgca gattatcaaa ttgtttatca accataatga
    12481 ttctctagga ggttagatgt gacattcaca tcatttgaac caacacgcaa tgtgcaagat
    12541 tttcatttgg cagcatttgc ctactatgat ggactagatg taatcgacca actcaagcca
    12601 ggaacacctg ttcagctagt cggagaacct tcaaacccac atgactcaga agctgtagca
    12661 atcttttatc agggcacaaa gttaggatat atcccatcgg ataaaaactc actaatcagt
    12721 cgcttaatct attttggaca cggcgatatt ctagaggcac gtattcagat gtccaataca
    12781 gaaaatcatc ctgatcgcca gtttcgagtc gttgtaaaac taaaagataa tcgtaaaaat
    12841 gatagtcggt aatttaccaa cctacccatt ttctacttaa cacggagctg tgctctctgt
    12901 ttttgttctt caataatgct taaaaaggct gcaaactccc tatctaggcg atgttggtag
    12961 gccttatttt ttattgtgag atcttccagg aacactggat aggttccttt tttatacaat
    13021 tctccttgaa agaagaagcg gtccgataat ttatcaactg aaacaagaga agaacgccag
    13081 cggcttttac gagaatgaga aggtttccaa gatattttta attgcttctc ataaaagtac
    13141 cagcccataa tatagatttt agtaatctga tttcgttttc tgtcttgata gaaacaagga
    13201 actgcataaa catttccatg ctttgtttgc aaaaaaggat ggaaatcttt tatcttttcg
    13261 tattctttct ttggaataag ggttaattga ttatccttaa taaccttctt ttcatcaata
    13321 gtatatgaat aacggtaggg gtcataaatg gttgattgtc cacgcgctct ataacgctct
    13381 gccatttcct taaaaatagg tagacgtcta taaccatcca tcagactaga tagactaagc
    13441 cctcgtcgat tattattttt cttcacacca agaatctggc aggtagacca ataattgata
    13501 ggaatggctc ctaatcctac cagaagaccg gcgctgtcaa aatgactggc aaagcgtacc
    13561 tcacgagtgt gaccagtctc atttttcaaa tcaacaaata caggttgctt gtcctgttca
    13621 aaaacaatta tataatttcc agaagactcc gtattttctc taattggaac ggtgtagaag
    13681 tggtgaaaat ttggtaattc tagtaacttt ccaagtgttg atgttttcat aacacaagta
    13741 taacaaaaaa tatttttcaa atccacaaaa atgtttaatt cgttaaacat agatataaag
    13801 aagctgggaa agacatccat gacgactttc ccactcccac cgtttattca aggataggtg
    13861 atgattgtct tatctaccga atcttctaaa gcctggcgcg attcttctga taaacgcaaa
    13921 tccgcaaggg tttgttctga aaaatagtag ggatttagac tatctacaaa tgcagaaatt
    13981 gaaatgacag ctttctccaa tatcagagat ttttcagtgt aagcaaaggg aatagcagac
    14041 caatcatcac tctcgaacat ttctaaaata tctttttgaa cttgaatttc agcctcattt
    14101 ttagctgaaa ctaggattgt ttttagtgta gcacgaaaac tttccttgtc ttgcaccaag
    14161 tcttccaagg tcaacaagct ttcatctgcc ttctcataga aaatatctaa ttccgtctct
    14221 gacgaagtag tcacatggag ccagtcagcc ttgatactgg ttttcattac tgcataggca
    14281 gaagcatttt caaagggact gctgcgcgtt tgaggataga gaacaatcca ctctttctgg
    14341 aatagattgt caggtttagc tattttcagt tcctcctcag aagctgtacc aatccgctgg
    14401 ctgatagcag tagtgtcatc ttgctgaaag aatccaatga tacgcggatt ttgcggaccg
    14461 ccaatggcat caatttttgt tcccagatca ttaataatgc gtatgttcaa ggcatgacac
    14521 tgctcattta atagtctatt ttgctctttt ccgagccagt agattccaat acaagataga
    14581 ccagtagcaa taagcaagac aagtaacagc actttcgagt atttcagcac agccatcaca
    14641 cctttctaaa
//
LOCUS       DBNFCO010000050        14617 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.050, whole genome shotgun sequence.
ACCESSION   DBNFCO010000050 DBNFCO010000000
VERSION     DBNFCO010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 14617)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14617)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14617
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.050"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            <1..259
                     /locus_tag="AC1PIV_001340"
     CDS             <1..259
                     /locus_tag="AC1PIV_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612361.1"
                     /translation="SSEEIQISGTITVLNTHDNTGKIQIESNEIPLGEYKFDVQKQIR
                     YPEYLSSAMRKKLRYRCYPKINFDPSTLKEKVIGVRIIEKL"
     gene            complement(322..1098)
                     /locus_tag="AC1PIV_001341"
     CDS             complement(322..1098)
                     /locus_tag="AC1PIV_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6261 family protein"
                     /protein_id="HIP6612362.1"
                     /translation="MKIRIPLYAQHLNQAEFTQLITSSVDTLKQYSSSTNDPMVTDLI
                     KQLEESLPLLKKSLKQKRGSDMTSNLNKALKNRKADYSAFVNGLKLFKNTRTPEKLQA
                     YHRLQELIKLYKNTRSTNMQESSALIDSLLARLAKPPYSEDVSLLMLDEAIANLRESH
                     ESTYRLYLKRSQDTSTREKINSLEVRKTAFNLYTLLYSHLVNKISYDPTAPEKVILQV
                     LNDIRQDFSERTRQKNQTETNSATINIVTTLPQGKEIETT"
     gene            1450..2067
                     /locus_tag="AC1PIV_001342"
     CDS             1450..2067
                     /locus_tag="AC1PIV_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5052 family protein"
                     /protein_id="HIP6612363.1"
                     /translation="MKWNKKLALSAVLVASLFTLSACQSISNWWKNTKEEWIGLEMTV
                     RTYDENSQLIDEMSGKSLSISRNQEFDSVDAEGYSNADSSVLKVTLGNYEIDHVGSSL
                     IAAEEGLEDLYAKYQTTVDIANYDRAIPLVNRMVSSLKNDFTGKAKVVLIRSQNGTPL
                     ATYVGDKVSLYASDAPKTSELLIDGKRLIIYRCDYTIYDRELLEN"
     gene            2068..2577
                     /locus_tag="AC1PIV_001343"
     CDS             2068..2577
                     /locus_tag="AC1PIV_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HIP6612364.1"
                     /translation="MIDIRSARIEDAADLVAIYAPYVEKTAITFETEVPTVEAFASRI
                     EKTLEKFPYLVAVEEGKVVGYAYASTYYARAAYDWTVELSVYIKQEARGKGIGTLLYN
                     ALEKDLTARGFKNFLACIALPNAASIALHEKRGYEQVAHFKKVGYKFDTWHDIVWLQK
                     FLVGKQNED"
     gene            2567..3220
                     /locus_tag="AC1PIV_001344"
                     /pseudo
     CDS             2567..3220
                     /locus_tag="AC1PIV_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754918.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            3229..3516
                     /locus_tag="AC1PIV_001345"
     CDS             3229..3516
                     /locus_tag="AC1PIV_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HIP6612365.1"
                     /translation="MSKVYEFETLIHPVPDKGGAYIIFPYDIREEFGKGRVKVHARFD
                     CHPYDGSIVNMGVKDEAGNICYIIGVQKAIRAAIGKQAGDRVQVTIQERME"
     gene            complement(4218..4994)
                     /locus_tag="AC1PIV_001346"
     CDS             complement(4218..4994)
                     /locus_tag="AC1PIV_001346"
                     /EC_number="1.97.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019321467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0043687 - post-translational protein
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HIP6612366.1"
                     /translation="MNTRKGIIFNIQHFSLHDGPGIRTTVFLKGCPLRCPWCANPESQ
                     KRKPEPMLDAVSKKMTIMGEEKSVDDIISEVMKDIDFYEESGGGLTLSGGEIFAQYEF
                     AKAILMEAKRHGLHTAIETTAFVEHHKFVDLIQYVDFIYTDLKHYNTISHRKVTGVNN
                     NLIIQNIQYAFSIGKEIVLRIPVIPDFNNSLEDAEQFACLFNQLKIDKVQLLPFHQFG
                     ENKYKLLNRTYAMTDVKALHPEDLKDYQAIFIKHNINCYF"
     gene            5126..5869
                     /locus_tag="AC1PIV_001347"
     CDS             5126..5869
                     /locus_tag="AC1PIV_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HIP6612367.1"
                     /translation="MERLDKIIQLVSQHEKIDVNSLAEQLDVSKVTIRKDLDKLESKG
                     LLRREHGYAVLNSGDDLNIRMSFRYDVKKRIAKEAANLIADNETIMIESGSTCALLAE
                     EICKTKRNVTIITNSYFIANYVRQYDSCQIILLGGEFQKDSQVTVGPLLHKMIQFFHV
                     DKAFVGTDGYDSEHGFTGKNLMRSEVVQYMSDVAENMIVLTDSSKFTKRGTVRRFGLS
                     QVAQVITDTSISEDLVKELENARVTVRLV"
     gene            5882..6856
                     /locus_tag="AC1PIV_001348"
     CDS             5882..6856
                     /locus_tag="AC1PIV_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HIP6612368.1"
                     /translation="MKQEKRRQLAKIAYLYYEEGKSQAEIAADTGIYRTTVSRMLTKA
                     KSEGIVKIEIQDFDRRLYRLEKYVQEKYGLKGLELVENSTDEDQLDLENRLAQAAADM
                     LTNLIDDGKKVGFSWGRSLSLIVDKIGNHRMKGVKFVPIAGGPSHIHARYHVNTLIYD
                     MANKFRGECSFINATIIQENQELAQGILSSKYFEELRADWKDLDVAAIGIGGRVDEKN
                     RQWLDMLTTADFQALSDEGAVGETCCRGLNQYGQAVVEDLQKRTIAISLDDLKEVPDT
                     IALAYGEEKAQAILAVLRAGYIHHLVTDERTIVKVLELDNDVHVHTNL"
     gene            7044..7367
                     /locus_tag="AC1PIV_001349"
     CDS             7044..7367
                     /locus_tag="AC1PIV_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HIP6612369.1"
                     /translation="MEMIVADQLIMGLIIYAGDAKSHAYQALSLVKAGEEERAEEELE
                     LADAALLEAHNMQTKFLAQEAGGAKSDITALFVHSQDHLMTSITEINLIKEIIDLRKE
                     LKKVG"
     gene            7400..7705
                     /locus_tag="AC1PIV_001350"
     CDS             7400..7705
                     /locus_tag="AC1PIV_001350"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HIP6612370.1"
                     /translation="MVKIALFCAAGFSTGMLVNNMKIAAADAGVEVEIDAHSQGKLAD
                     YLDEIDVALLGPQVAYTLDKSKALCDEKQVPIAVIPMADYGMLDGKKVLQLALSMVS"
     gene            7718..9019
                     /locus_tag="AC1PIV_001351"
     CDS             7718..9019
                     /locus_tag="AC1PIV_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HIP6612371.1"
                     /translation="MSKIDTQKIIVPIMKFVNMKGIIALKDGMLAILPLTVVGSIFLI
                     LGQLPFEGLNAAIASIFGAEWTEPFMQVYSGTFAIMGLISCFAIGYSYAKNSGVEPLP
                     AGVLSLSSFFILLKSSYIPVDGEPIGDAIAKVWFGGQGIIGAIIIGLVVGAIYTTFIQ
                     RHIVIKMPEQVPQAIAKQFEAMIPAFVIFLLSMIVYIVSKMATNGGTFIEMIYDVIQV
                     PLQGLTGSLPGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKALLAADKLS
                     LENGAHIVTQQFLDSFLIMSGSGITFGIVFAMLFAAKSKQYKALGKVAAFPALFNVNE
                     PVVFGFPIVMNPVMFLPFVLVPILAAFIVYGAISIGFMQPFSGVTLPWSTPAIISGFM
                     VGGWQGAVVQIIILAVSTIVYFPFFKIQDKIAYESETKEPV"
     gene            9171..11615
                     /locus_tag="AC1PIV_001352"
     CDS             9171..11615
                     /locus_tag="AC1PIV_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002910747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HIP6612372.1"
                     /translation="MKTVTEVAGTSIKTEYFGSLTDRMNKYREDVLDKKPYIDAERAV
                     LATKAYQEHREKPNVLKRAYMLKEILENMTLYIEEESLIAGNQASSNKDAPIFPEYTL
                     EFVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWEKNNLRSRAGVLLPEEVQVYMET
                     GFFGMEGKMNSGDAHLAVNYQKVLEQGLRGFEERVRVAKANLDLTDPASIDKYHFYDS
                     IFIIIDAVKAYADRFVALATELAEKAPTAQRRQELLEIARICAKVPYEPAETFAEAVQ
                     SVWFIQCILQIESNGHSLSYGRFDQYMYPYVKADLEAGRETEDSIVERLTNLWIKTIT
                     INKVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTV
                     RYHAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIEKGVLEEDAYDYSAIGCVET
                     AVPGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPAFGHFKDMKSFEVLETAW
                     EKTLRHLTRMSVIVENAIDIALEREVPDILCSALTDDCIGRGKHLKEGGAIYDYISGL
                     QVGIANLSDSLAAIKKLVFEEGRLTPEELWHALETDYAGERGKEIQEMLIEDAPKYGN
                     DDDYADQLVTAAYDIYINEIAKYPNTRFGRGPIGGIRYSGTSSISANVGQGRGTLATP
                     DGRNAGTPLAEGCSPSHNMDKNGPTSVLKSVAKLPTHEIVGGVLLNQKVNPQTLAKEE
                     DKQKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQLHPEKHRDLIVRVAGYSAFFNVL
                     SRATQDDIIGRTEHTL"
     gene            11630..12298
                     /locus_tag="AC1PIV_001353"
     CDS             11630..12298
                     /locus_tag="AC1PIV_001353"
                     /EC_number="4.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HIP6612373.1"
                     /translation="MEFMLDTLNIEEIRKWAEVLPLAGVTSNPTIARKEGDIDFFERL
                     HLIRDIIGPNASLHVQVVAKDYEGILADAKKIRELAPENIYIKVPVTPAGLAAMKTLK
                     AQGYQITATAIYTVFQGLLAIEAGADYLAPYYNRMANLNIDSNAVIAQLSEAIDRECS
                     ESKILAASFKNVDQVNQAFANGAQAITAGADIFEAAFSMPSIEKAVNDFADDWSAIHG
                     RYTI"
     gene            12330..13286
                     /locus_tag="AC1PIV_001354"
     CDS             12330..13286
                     /locus_tag="AC1PIV_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HIP6612374.1"
                     /translation="MKQFSGLSRTIQGNHLLDTCAIDILKIGHRPLVLCAKQEYNTTV
                     ESFVKVLTCHGLIVKIAYMEEWDQNSVEEYGEVGFRHRADHIIGIGNSSVAACTKAVA
                     DLLDLPAVLIPTSQFTTLPWVSVENKKRERPLFNESIQLIIADREQLLTQPTSELING
                     VVNTLLYLAAIKEVQRNHLFSLIDDILIRDFESVLLRSSLQAIENFEARILSKEVQDV
                     LEVLSTCVTLDLPSDAWDVIQQIESKLSERREDLVDEPLKRNVVLYLLLTYLTQESEE
                     FQARLKWSQQLLLSANSSNLLSLEAVFKEIALEMGEDGSTRC"
     gene            13407..14501
                     /locus_tag="AC1PIV_001355"
     CDS             13407..14501
                     /locus_tag="AC1PIV_001355"
                     /EC_number="1.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002910745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008888 - glycerol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HIP6612375.1"
                     /translation="MKVFASPSRYIQGKHVLFQGAEAIGKLGTKPLILCDDLVYGIIG
                     EKFLSYLVEEGMQVHRVAFNGEASDKEIQRVVEIGKEQASDVVIGLGGGKTIDSAKAI
                     ADLLGVPVVIAPTIASTDAPTSALSVIYSEEGAFERYIFYKKNPDLVLVDTAIICQAP
                     PRLLASGIADGLATWVEARAILQSNGTTMAGGGQTLAGIAIAQTCEQTLFEYGLQAMA
                     SCEAKVVTAALENIVEANTLLSGLGFESAGLAAAHAIHNGFTALEGDIHHLTHGEKVA
                     YGTLTQLFLENRPKEELEKYIRFYQALNLPTTLEELHLADASYEELLKVGQQATIEGE
                     TIHGMPFAISAEDVAEALMAVDYYVRSLDK"
BASE COUNT         4413 a         2549 c         3288 g         4367 t
ORIGIN      
        1 ttcttccgaa gagattcaaa tttcgggcac aattacagtt ttaaatacac atgataacac
       61 tggaaaaata caaattgaat caaatgaaat tccgttgggt gaatataaat tcgatgttca
      121 aaaacagatt cgctaccctg aataccttag ttcagctatg agaaagaaat tgagatatag
      181 atgttatcct aaaataaatt tcgatccgtc aactttgaaa gagaaagtta ttggtgtgcg
      241 gattattgaa aaattgtagt tcaagaacat tcaatacttt cagaaaatac cccctaatca
      301 tgttgactag ggggtatttt tctaagtcgt ttctatctct tttccttgcg gtaaggttgt
      361 tacaatgttt attgtagcgg agttagtttc tgtttgattt ttctgtcgcg ttctttctga
      421 aaaatcttgg cgaatatcat ttaggacttg caagataact ttttcagggg ctgttgggtc
      481 atagctgatt ttattgacca agtgactata aaggagggtg tacagattga aggctgtttt
      541 tcggacttcc aagctgttta ttttttcgcg agtgctggtg tcctgacttc ttttcagata
      601 gagacgatat gtactttcat ggctttcacg gagattggca atagcttcat ctaacataag
      661 taggctaaca tcttctgagt agggtggctt cgccagtcgg gctagcaaag aatcaatcaa
      721 agcagatgat tcttgcatat tggtagacct tgtatttttg tatagtttga tgagttcttg
      781 tagtcggtga taggcttgta atttctcggg tgtccgagta tttttaaaaa gtttgagtcc
      841 gttgacgaag gcagagtagt cagcctttcg attctttaga gccttgttta agttactagt
      901 catgtctgag ccacgttttt gtttgagact ttttttcagt aagggtaagg attcttcaag
      961 ctgtttgatt aagtccgtta ccatggggtc attggtggaa gaactgtact gtttcaaggt
     1021 atcaacacta cttgtgatca attgtgtaaa ttctgcttga ttcagatgtt gtgcatataa
     1081 agggattcgg attttcattt gtgtacctca ctatcttttt ttccggtcat cttatttatt
     1141 cgtaaataag tagaaaaaaa tagaattatt taaaaaattt tttaaaactt gtcaaaacag
     1201 tacatttacc tataataaaa ttgtgttttt aaggaattgc atcaaaacac aatgatataa
     1261 atgtttggaa atagcaaatt agtttgactt gcatatttaa aaattgtttt tggaataaaa
     1321 ttattgatta ggcttgtttt caaattgaaa ggatatgatc tcagtttgtt tattgaatac
     1381 cttgcacaca tttttctttg tttaggcaat tccgtggtac aataaggtat caaccattgg
     1441 aggttttata tgaaatggaa taaaaaacta gcacttagtg ctgtcttagt cgcaagtttg
     1501 tttactttgt cagcctgtca gtcgatttca aattggtgga aaaataccaa ggaagaatgg
     1561 attggcttgg agatgacggt acggacttat gatgaaaatt ctcagttgat agatgaaatg
     1621 tctggtaagt ccctatcgat ttcgcggaat caggaatttg actcggtgga tgccgaaggc
     1681 tattccaatg cggattcttc tgtcttgaag gtgacacttg ggaattacga aattgaccac
     1741 gtaggctcat ctttgattgc ggcagaagaa ggtttggaag acttgtatgc gaaatatcag
     1801 accacagtag atatcgcaaa ttacgatcgt gcaattccgc ttgttaaccg tatggtatct
     1861 agtctcaaaa atgattttac aggtaaggca aaggtggtct tgattcgttc gcaaaacgga
     1921 accccgcttg ctacttatgt aggtgataaa gtatctcttt atgcatctga tgcacctaag
     1981 acttctgaac tcttaattga tggcaagcgg ttgattatct accgctgtga ttatacaatt
     2041 tatgatagag aattattgga gaactaaatg atagacattc gttccgcaag gatagaggat
     2101 gcggcagacc ttgtggcaat ttatgctcct tatgtagaaa agaccgctat tacctttgaa
     2161 acagaagtac cgactgtcga agcctttgca agtcgaattg aaaagacctt ggagaagttt
     2221 ccctatctgg tcgcagtaga agaaggtaaa gttgtgggtt atgcctacgc ttcaacttac
     2281 tatgcccgtg cggcttacga ttggacggtg gaattatccg tatatatcaa gcaagaagcg
     2341 cgcggaaaag gaattggaac tcttctctac aatgctttgg aaaaggacct gacagcgcgt
     2401 ggttttaaaa atttcttagc ctgtatcgcc ctaccaaacg cagcctctat agcactccat
     2461 gagaagaggg gctatgaaca ggtggctcat ttcaaaaaag ttggttataa atttgatacc
     2521 tggcatgata ttgtctggct tcaaaaattt cttgtaggta agcaaaatga agattaacga
     2581 attagaaaaa cgtttgttgg ccgtggcgga tgctagtcag gcccagccta tgaaagctta
     2641 tatgaaaaat aactttgaat tcttaggtgt acgaacgcct gaccgccgaa aagttgcgaa
     2701 gcagtttttc aaagatttca aggctcaggg aattgactgg gactttgtag aggcttgctg
     2761 gtctaagccc taccgtgaat ttcaatatat cgctattgat tacctagtta ccaagaagaa
     2821 agacttggtt ctagctgatt tacctcgttt gaaagagcta gctcagacca agtcttgatg
     2881 ggatagtatt gacggtctag ataagctagt tggtaagatt atcttggaaa atccagaggc
     2941 caagcagaca atcttggaat ggagtttgga taatgatttc tggttgagac ggattgccat
     3001 tgaccaccag cttctccaaa aagaaaagac agatacgaaa ctgttggaac aaatcctaat
     3061 caataatctc aatcagactg aattttttat caataaggca attggctgga gtttgcggga
     3121 ttattccaag accaatcctg aatgggtacg agtttttctt accaagtaca gctcacaaat
     3181 ggcaggcttg tccattcgcg aagccagtaa gtatatctag gaggagccat gtccaaagtc
     3241 tatgaatttg aaacccttat ccatccagta ccggataagg gcggagccta tatcatcttt
     3301 ccctatgata tacgagaaga gtttggtaag gggagggtaa aggtacatgc cagatttgat
     3361 tgtcatccct atgatggctc cattgtcaat atgggagtta aggatgaagc aggcaatatc
     3421 tgttatatta ttggcgttca aaaggctatt cgagcggcta ttggaaaaca ggctggtgat
     3481 agagtacagg taaccattca agaacgaatg gagtaatcag gcttgcaaat ccttgagatt
     3541 atggtagaat agaatcatgc gatgagccga gtagtggggg gattaaggtt cagcacactt
     3601 ctaagagttc gtgtcaacat ctcagcgcag tggttgattg gcagatttgt tcgtatttta
     3661 tactccaaat ctgacctaat caactgtgcg ggggtgggaa gacgaactct tggttgacaa
     3721 gttgagttct ttcccactcc cttcgacgct agggaggtct tcatttaatt gaaacgcagg
     3781 agcggacctt gaatagttgt gtgaaccttc tattctcatc ggaaacgatg cccttgccca
     3841 cctttatggt gggctttttg tatactaagt gaggctgggc aaaaagccct ggcccacttc
     3901 tcagtgttcg tgtcaacatc tcagcgcagt ggttgattgg gtttaacagt ccagtggact
     3961 gttaaaggta ggagataaga tttgcgaagc aaatctcagc aattcgtgtt ttacactcga
     4021 aatctaacct aatcaactgt gcgggggtgg gagtgaaaca gtctggggat agactgtttc
     4081 agctcaacaa cttaaaacga aaaattgttg acgaaccttt tttgacttag tcgatgtctt
     4141 tcccactccc atttcagtat gtgatttcta taggaatgct attggctcag ccgaggaagt
     4201 ttttatattt ctcaaagtta gaaataacag ttgatattat gtttgatgaa gattgcttga
     4261 tagtctttta aatcttctgg atggagagcc ttgacatcgg tcatagcata ggttcgattg
     4321 agaagcttat acttattttc tccaaattga tggaagggga gtagttgaac tttgtcaatc
     4381 ttgagttgat taaagagaca ggcgaattgt tcagcatctt cgagggaatt attaaagtca
     4441 gggataacag ggatacgtag gacgatttct ttcccgatgg aaaaggcgta ttggatattt
     4501 tgtatgataa ggttattatt gacgccggtg acttttctat gagaaattgt attgtaatgt
     4561 tttaaatcag tatagataaa gtcaacgtat tggataaggt caacaaattt gtggtgttct
     4621 acgaaagcgg tggtttcaat agcggtatga aggccgtgtc tttttgcctc cataagaata
     4681 gctttcgcaa actcatattg ggcaaaaatt tctccgccag acagcgtgag cccaccacct
     4741 gattcttcat aaaaatcaat atctttcatg acttcggata tgatgtcatc aacagatttt
     4801 tcttctccca tgatggtcat ttttttacta acagcatcaa gcatgggttc aggttttcgt
     4861 ttttgagatt ctggatttgc acaccaagga caacgtaggg ggcaaccttt caagaaaacc
     4921 gtcgtacgta taccaggacc gtcatggagc gaaaaatgtt gaatgttaaa aataatgcct
     4981 tttcgtgtat tcatgctctt tctccttttc gattaatttg attttatcac acaaaagaaa
     5041 gttttacaat tacgaacgta agttaaaaag ttgcaaatag ttgaaaaaga gtcaaaattt
     5101 gatagaataa tgatgaggtg atgaaatgga acgattagat aaaattatac aactggtatc
     5161 acaacatgaa aaaatagatg tcaatagctt ggcggagcaa ctggacgttt ctaaggtaac
     5221 catccgtaaa gatttagata agttagaatc aaaaggttta ttacgtagag aacatgggta
     5281 tgctgttcta aatagtggtg atgaccttaa tattcggatg tcctttcgct atgatgtaaa
     5341 aaaacgaatt gcaaaagaag cagcaaatct cattgccgac aatgaaacga ttatgataga
     5401 gtctgggtca acttgtgctc tcttggcaga agaaatttgc aaaaccaaga gaaatgtgac
     5461 catcataaca aattcttatt ttatagccaa ttatgtgcga caatatgata gctgtcagat
     5521 tattttattg ggtggtgagt ttcaaaaaga ttcccaagta actgttgggc cgctcttgca
     5581 taaaatgatt cagtttttcc atgttgataa ggcttttgta ggaactgacg gctatgatag
     5641 tgagcatggt tttacaggta aaaacttaat gcgaagcgaa gtagtacagt acatgtctga
     5701 cgttgctgaa aacatgattg tgctaacaga ttctagtaaa tttacaaaac gagggacagt
     5761 acgcagattt ggtttaagtc aagttgctca ggtcattaca gatacgtcga tttctgaaga
     5821 tcttgtcaag gaattagaaa atgctagagt cacagtaagg ctagtttagg ttgggggcag
     5881 tatgaagcaa gaaaaaagaa ggcagttggc aaaaatagcc tatctttact acgaagaggg
     5941 gaaaagccaa gctgagattg ctgctgatac aggaatttat agaacgacag tcagtagaat
     6001 gttgaccaag gctaagtcag aaggcattgt aaaaatagaa attcaagatt ttgataggcg
     6061 cctatatcga ctagaaaaat atgttcaaga aaaatatgga ttaaaaggtt tagaactggt
     6121 tgaaaacagc accgatgagg accagcttga tttagaaaat cgtctggcac aggctgcagc
     6181 cgatatgctt accaatctaa ttgatgatgg aaagaaagtt ggtttttcat gggggagaag
     6241 cctcagtctt attgtagata agatagggaa tcatcgtatg aaaggtgtca aatttgttcc
     6301 aatagctggc ggtccaagtc atatccacgc acgttatcat gtgaatactc tgatttacga
     6361 tatggccaat aaatttcgtg gagaatgtag ttttatcaat gcgacgatta tccaggagaa
     6421 tcaagaactt gctcaaggta ttctttcttc taaatatttc gaggagctac gtgctgactg
     6481 gaaggactta gatgtagcag caataggtat tggcggtcga gtcgatgaaa aaaatcgtca
     6541 atggttagat atgttgacga cggctgattt tcaagccttg tcagatgaag gtgcagtcgg
     6601 tgaaacctgc tgtcgtggtc tgaatcaata cggtcaagct gtcgtggagg atttgcaaaa
     6661 gaggaccatt gccatctctt tagatgattt aaaagaagtc ccagatacaa tagctcttgc
     6721 atatggggag gaaaaggctc aagccatttt agctgtattg cgagctggct acattcatca
     6781 tctggtaaca gatgaacgaa ccatcgtaaa agttttagaa ctggataatg atgtgcatgt
     6841 ccatacaaat ttgtaagaga gtacttcaat cacttaaagg tggttgaagt attttttatc
     6901 ccaaaaaatg cacaaaagtg cagaaataaa ttaaaacaga aaatgttcta taaatatatt
     6961 tacgctataa agagaaaatg atatgattta cttacgaaag aaatataata acttacaaat
     7021 aaaacaaatc ggaggaaaaa gaaatggaaa tgattgttgc agatcaattg atcatgggat
     7081 tgattattta tgctggagat gcgaaaagtc acgcctacca agctttgtcg cttgtcaaag
     7141 caggtgaaga agagcgagca gaagaggaat tagaattggc agatgcagca ttattagaag
     7201 ctcacaatat gcagacaaaa ttcttagcac aggaagctgg tggagcaaaa tctgatatta
     7261 cagcactatt tgtccattcg caagatcatt tgatgacgtc tattacagag atcaatttga
     7321 ttaaagaaat cattgatttg cggaaagaac taaaaaaagt tggctaaaac aaaaaaatta
     7381 tatttaggag gaaaccgaaa tggttaaaat cgctctattt tgtgccgctg gtttttctac
     7441 aggcatgttg gtaaacaaca tgaagattgc agcagcagac gcaggtgtcg aagtagaaat
     7501 cgacgcgcat tcccaaggga aacttgcaga ttaccttgac gaaatcgatg tagctttact
     7561 gggaccacaa gtagcatata cgcttgataa gtcaaaagcg ctctgtgatg aaaagcaagt
     7621 ccctattgcc gtgattccaa tggcagacta cgggatgttg gacgggaaaa aagttcttca
     7681 attggcactc agcatggttt cataaaggag tatggtcatg tccaaaattg atacacaaaa
     7741 aattattgtc ccaatcatga aatttgtgaa tatgaaaggg atcatcgctc taaaagatgg
     7801 tatgttggct atcttacctt taacagtagt tggtagtatt ttcttaattt tggggcagtt
     7861 gccttttgaa ggcttaaatg ccgcaatagc ttctatattt ggagcggaat ggactgaacc
     7921 gtttatgcaa gtctatagcg gaacctttgc gattatgggc ttgatttctt gttttgcgat
     7981 cggctattct tatgccaaaa atagtggagt tgagcctctc cctgcgggtg tactgtcctt
     8041 gtcttcattc tttatcctct tgaaatcatc ttatattcca gttgatggag aaccaatcgg
     8101 tgatgccatc gcaaaagtat ggtttggtgg tcaaggaatt atcggtgcga ttattattgg
     8161 tttggtagtg ggcgctatct atacgacttt tattcagcgt catattgtta tcaagatgcc
     8221 tgaacaagta ccgcaagcta ttgccaagca gtttgaagct atgattccag cttttgtcat
     8281 ctttttgcta tctatgattg tctatattgt ttccaagatg gcgacaaacg gtggtacatt
     8341 cattgaaatg atttacgatg tgattcaagt gccactacaa ggtttgactg gttcattacc
     8401 aggtgcgatt ggaattgctt tcttcatttc cttcctctgg tggtttggtg tacatggcca
     8461 gtcagttgtc aatggtgtcg ttactgcttt actattgtca aacctcgatg ccaataaggc
     8521 ccttttagca gcagataaat tgtctctgga aaatggcgcc cacatcgtga cccaacaatt
     8581 cttagatagt ttcttgatta tgtcaggttc aggtattacc ttcggtattg tttttgcaat
     8641 gctatttgcc gctaaatcaa aacaatataa ggctcttggt aaggtagcgg cctttcctgc
     8701 actctttaac gtaaatgaac cagtcgtctt tggttttcca attgtgatga atcctgtaat
     8761 gttcttacca tttgttttgg taccgatctt agcggctttc attgtctacg gtgcaatctc
     8821 aataggcttt atgcaaccat tttcaggtgt gaccctacca tggtctaccc cagcaatcat
     8881 ttctggtttt atggtgggtg gttggcaagg tgcagttgtt caaatcatta ttttagctgt
     8941 ctcaactatt gtttatttcc cattcttcaa aatccaagat aagattgcct atgaaagtga
     9001 aacgaaagaa ccagtttagt caatgatgtc agacaaaaga gttgcacaaa tgtgcagccg
     9061 gcttcggaaa tcttagcgct cactagcatc aattgacaat aacccctatt acaggatata
     9121 cttaatttac aaacgaaaca aaattaagtt tcgaaagaaa gggtaaaact atgaaaacag
     9181 tgactgaagt agctggcact agcattaaaa ctgagtattt tggaagtctg actgatcgga
     9241 tgaacaaata cagagaagat gtccttgata agaagcccta tattgacgcg gaacgggctg
     9301 ttttagcaac aaaagcctat caagaacata gagagaagcc caatgtatta aaaagggcct
     9361 atatgctcaa ggaaatattg gagaacatga cgctttatat tgaagaagaa agtctgattg
     9421 caggtaacca agcttcttca aataaagatg ctcccatctt cccagaatat accttggagt
     9481 ttgtattgaa tgaattggat ttattcgaaa aacgggatgg ggatgtcttc tatattaccg
     9541 aggaaactaa agagcagttg cgcagcatcg ctccattctg ggaaaagaat aatcttcgtt
     9601 cacgtgcagg tgtcttgctt ccagaagaag ttcaagttta tatggaaact ggcttctttg
     9661 gtatggaagg taagatgaac tctggcgatg cccacttggc tgtcaattac caaaaggtat
     9721 tggaacaagg tttgcgtggt tttgaggagc gagttcgtgt agcaaaggct aatctcgatt
     9781 tgacggatcc tgcaagtatt gataaatatc atttctatga ctcaatcttt atcatcattg
     9841 atgcggtgaa agcatacgca gatcgttttg tcgccttggc tactgaattg gcagagaaag
     9901 caccaacagc tcaacgccgt caagaactac tggagattgc acggatttgt gcgaaggtgc
     9961 cgtatgaacc tgctgaaaca tttgcagagg cagtgcaatc ggtctggttt atccagtgta
    10021 tcttgcaaat cgagtccaat ggacattctc tatcctatgg acgtttcgac caatacatgt
    10081 atccgtatgt gaaagctgat ttagaagcag gacgtgaaac ggaagacagc atcgtcgaac
    10141 gcttaactaa cttgtggatt aagaccatta ctatcaacaa ggttcgtagt caatcacata
    10201 ccttctcatc tgctggtagt ccactatacc aaaatgtaac cattggtgga caaacacgtg
    10261 ataagaagga tgctgtcaat ccactttctt acttagtatt gaaatctgtt gcccaaacac
    10321 acctgccaca gccaaacttg actgttcgct atcatgcagg cctagatgct cgcttcatga
    10381 atgaatgtat tgaagtcatg aaacttggtt ttggtatgcc tgcctttaac aacgatgaaa
    10441 ttatcattcc ctcctttatc gagaaaggtg tcttggaaga agatgcctat gactacagtg
    10501 cgattggctg tgtagaaacg gctgttcctg gtaaatgggg ataccgttgt acaggtatga
    10561 gctatatgaa cttcccgaaa gttttattga ttaccatgaa tgatggtatc gatcctgcat
    10621 caggcaaacg gtttgcacca gcctttggtc acttcaaaga tatgaaatcc tttgaagtgc
    10681 ttgaaacggc atgggaaaag acacttcgtc atctaacacg gatgagtgtc atcgttgaaa
    10741 atgcaattga cattgcttta gaaagagaag taccagacat tctctgctca gctctgacag
    10801 atgactgtat cggtcgtggt aagcacctga aagaaggtgg agcgatttac gattacattt
    10861 ctggtctgca ggttggcatt gccaatttat ctgattctct agcagcaatc aaaaaattag
    10921 tctttgaaga aggacgattg actccagaag aattatggca tgctttggaa acagactatg
    10981 ctggggagcg tggtaaagaa atccaggaaa tgttgattga agatgcacca aaatatggta
    11041 acgatgatga ttatgcagac caattggtaa cagcagcata tgatatttat atcaatgaga
    11101 ttgccaaata tccaaacact cgctttggtc gtggtccgat tggtggtatc cgctattcag
    11161 gtacatcatc catttcagcc aacgttggac aggggcgtgg tactttggca actccagacg
    11221 gtcgcaatgc aggaacaccg ttggcagaag gttgttctcc atcacataat atggataaaa
    11281 atggaccgac atccgttttg aaatcagttg ccaaattacc aacacatgaa attgttggag
    11341 gcgttctgct caatcagaag gtcaatccac aaacacttgc caaagaagaa gacaaacaaa
    11401 aattaattgc cctcttgcgg acattcttta accgcttgca tggctatcat attcagtaca
    11461 atgttgtctc tcgagaaacc ttgattgatg cacaactaca tcctgaaaaa caccgtgatt
    11521 tgattgtccg tgtagcaggt tattcagcat tcttcaatgt attgtcgaga gcaacacaag
    11581 acgacatcat tggtcgtaca gaacatacat tgtaaaagag gttattatta tggaattcat
    11641 gctggacacc ttaaatatag aggaaatacg aaaatgggct gaggttttac cccttgcggg
    11701 ggtgacctca aacccaacga ttgcgaggaa agaaggtgac attgactttt ttgaacgttt
    11761 gcaccttatc cgtgacatca tcggtccaaa tgcttcacta catgtgcaag ttgtggcaaa
    11821 ggattatgaa gggattttgg cagacgctaa aaaaattcgt gaattggcac cggaaaatat
    11881 ctatattaag gttccggtaa cgcctgctgg tttggctgct atgaaaacat tgaaagcgca
    11941 aggttatcag attacagcaa cagcgattta taccgttttt cagggcttgt tagctattga
    12001 agcgggtgca gattacttag cgccgtacta caatcgcatg gccaatctga atattgattc
    12061 gaatgcggtc atcgctcagt tatcagaagc gattgatagg gagtgttcgg aaagtaaaat
    12121 tttagcagca tcattcaaaa atgtggatca agtgaaccaa gcatttgcaa atggggcgca
    12181 ggctattacg gcaggtgcag atatatttga agcagccttt tctatgccat ccattgaaaa
    12241 ggcggtaaat gattttgcag atgattggtc tgccattcat ggaaggtata ctatctaaac
    12301 atttctatat tataaaatag gggggcacta tgaaacaatt ctcaggtctt tcacgcacta
    12361 tccaaggaaa tcatctttta gacacttgtg cgattgacat tttgaaaata ggtcatcgtc
    12421 cccttgtttt atgtgcaaaa caggagtata atacaactgt agaaagtttt gtgaaagttt
    12481 taacttgtca tggacttatt gttaaaatag cctatatgga ggagtgggac cagaactcgg
    12541 ttgaagaata tggggaagtt ggtttccgac atcgtgcaga ccatattatt ggcattggta
    12601 atagttctgt ggcagcttgt acaaaggctg ttgcagattt actagacttg ccagctgttc
    12661 ttataccgac ttcacagttt accactctac cttgggtatc ggtggaaaat aagaaaagag
    12721 agcgaccatt gtttaatgag tccatccagc taattatagc ggatagggag caattattga
    12781 cacaacctac ctcggagttg ataaatggag tggtcaatac tcttctttat ctagcagcca
    12841 taaaagaagt acaaagaaat catctattca gcttgataga tgatattctt atcagagatt
    12901 ttgaaagcgt tttattaaga agtagtcttc aagctataga gaattttgaa gctcggatat
    12961 tatcaaaaga agtacaagat gtcttagaag ttctttctac ttgtgtaaca ttagacctgc
    13021 ctagtgatgc ttgggacgtg attcaacaaa tagaatcaaa gctcagcgaa agaagagagg
    13081 atttggtgga tgagccattg aaacgaaatg ttgtcctcta cttgcttctg acctatttga
    13141 cacaggaatc agaagaattt caagccagac tgaagtggag tcaacagttg cttttgtctg
    13201 ccaactctag caatctattg tcgctggagg cagttttcaa ggaaattgca ctagagatgg
    13261 gagaagatgg ctcgacacgt tgttagtagg catcgctgta caatggcaat atttaaaatg
    13321 caggctcata cctcttactt tcggcaatgc tcactgtcgt ttattactca atataacact
    13381 atctattatt tcaaggagga attcttatga aagtatttgc aagtccatct cgctatattc
    13441 aaggtaaaca tgtccttttc caaggtgcag aagctatcgg aaaattggga acaaagcctt
    13501 tgattctttg tgatgattta gtatatggga ttatcggtga gaagtttttg tcctatctcg
    13561 ttgaagaagg gatgcaagtc catcgtgttg cctttaatgg agaagcatct gacaaggaaa
    13621 tccagcgcgt cgtagaaatc ggaaaagaac aggctagtga cgtcgtaatc ggtctaggtg
    13681 gtggcaagac gattgactca gccaaggcga ttgctgattt actaggagtg ccagttgtca
    13741 ttgctccaac tattgcttca acagatgctc cgacctctgc tttatctgtc atttattctg
    13801 aagaaggggc gtttgaacgc tatattttct ataagaaaaa tccagatctt gtcttggtag
    13861 atacagcgat tatttgtcaa gcaccgccac gtcttttggc ttctggtatt gcggatggct
    13921 tggcgacgtg ggtggaagcg cgtgctattt tacaaagcaa tggaacaaca atggcaggag
    13981 gaggtcagac acttgctggt atcgctattg cacaaacctg tgaacaaaca ctctttgaat
    14041 acggacttca agccatggcc agctgtgaag ccaaggttgt gacagctgct ttagagaata
    14101 ttgttgaagc caataccttg ctaagtggtt taggctttga aagtgcaggt ttggctgcgg
    14161 cgcatgcgat acacaatgga ttcaccgcct tggagggaga cattcaccat ttgacacatg
    14221 gtgaaaaagt ggcttatggg accttgaccc agctcttttt ggaaaaccgt cctaaagaag
    14281 aattggaaaa atacatccgt ttctatcaag ccttgaatct tccaacaact ttggaggagt
    14341 tacatttggc tgatgctagt tatgaagaac tattgaaagt cggccaacaa gcgacgattg
    14401 aaggagaaac aattcacggt atgccatttg ctatttcagc agaagacgtt gcagaagctc
    14461 tgatggcagt tgactactat gttcgctcat tagataaata agaagagcat tcacagttga
    14521 gcatgtccat ctaaactggt gaatagaggt tcgaagtaat tgccttggga aattctttct
    14581 cagggctttt catttgaaaa aattatgata taattgt
//
LOCUS       DBNFCO010000051        14147 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.051, whole genome shotgun sequence.
ACCESSION   DBNFCO010000051 DBNFCO010000000
VERSION     DBNFCO010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 14147)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14147)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14147
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.051"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            111..299
                     /locus_tag="AC1PIV_001356"
     CDS             111..299
                     /locus_tag="AC1PIV_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HIP6612376.1"
                     /translation="MKLPQFLFLAITTILAVYFMNASILTGDFLIAGIYAFIAYRNLH
                     FAYKVTKFIRLVEKQTKK"
     gene            complement(265..1221)
                     /gene="birA"
                     /locus_tag="AC1PIV_001357"
     CDS             complement(265..1221)
                     /gene="birA"
                     /locus_tag="AC1PIV_001357"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     ligase/biotin operon repressor BirA"
                     /protein_id="HIP6612377.1"
                     /translation="MKTYQKIYLLLKEREDYVSGEDLAQELGISRTSIWKAIRQLETH
                     GLTIEAARNRGYRLAEGDLLLPELISQELQLPVHLNMDSDSTQLDAKQGIESGHTSPA
                     LYLAPYQNKAKGRFGRPFYASKSGGIYMSLRLSPNVPFLEFKPYTILAAAAVVKAIQS
                     LCDLDVQIKWVNDIYLGHKKVAGILTEAISSMENQRVTDVIIGVGINVRIDDFPKELQ
                     QSAGNLFEEQPPFTRNQLITAIWKAFLETDEKELIALYKEKSLVVGQQVSFVENQVEF
                     KGTAIAVTDTGNLVIQLDNGKAKIISSGEISLTSWSASPPNE"
     gene            1286..2320
                     /locus_tag="AC1PIV_001358"
     CDS             1286..2320
                     /locus_tag="AC1PIV_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HIP6612378.1"
                     /translation="MKTLDYIVTLTNTPSPTGFTTDIMNYIKAEVESFGYVASKTAKG
                     GVLVTVPGENDQEHRMVTAHLDTLGAMVRAVKPDGRLKMDLVGGFGYPSIEGENCLIH
                     CAKNGKTFTGTILMHQTSVHVYRDASTAERNQTNMEIRLDEKVTNADETQALGIEVGD
                     FISFDPRTVVTETGFIKSRPLDDKVSAAILLHLLKVYKEEGATLPYTTHFYFSNNEEI
                     GYGANSSIPAQVVEYLAVDMGAMGDDQQTDEYTVSICVKDGSGPYHYELRQHLIALAE
                     RDGIPYKLDIYPYYGSDASAAMRAGADVKHALLGAGIESSHSYERTHLDSVVATERMV
                     DAYLKSAMVD"
     gene            2322..3059
                     /locus_tag="AC1PIV_001359"
     CDS             2322..3059
                     /locus_tag="AC1PIV_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612379.1"
                     /translation="MNETRFLELFNDLDKVLRKVCGVADGEYADVGSMLTKAKELTRH
                     NPVEANWDKLYVARQLRNLMVHEKRTGLKEVAQPSQELITVLEKVIAQYQEPITIADY
                     LQKTQKIKPVIFEGKDKLTKALEIVEQEHFSKFPIFSDKVYQGLVSDKGLTNWLAKAS
                     KETGSIREKLVEASLEDVLACEEDSIQVIVLPITAHLYQVINHFEGRKRTTVLVSRQA
                     SGKLHSPEDLVGIVTAQDLAEIYGMVD"
     gene            3078..3545
                     /locus_tag="AC1PIV_001360"
     CDS             3078..3545
                     /locus_tag="AC1PIV_001360"
                     /EC_number="3.5.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004132 - dCMP deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006220 - pyrimidine nucleotide metabolic
                     process [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxycytidylate deaminase"
                     /protein_id="HIP6612380.1"
                     /translation="MSTNRLAWDEYFAAQALLIANRATCKRAKVGAVLVKDNKVIATG
                     YNGSVSGTEHCLDQECLMIDGHCARTLHAEVNAILQGAERGIPKGFTAYVTHFPCLNC
                     SKQLLQVGCKRVVYINEYRMDDYAQYLYKEKGCELVHLPLEVVKQAFADAEFI"
     gene            3944..5134
                     /gene="metK"
                     /locus_tag="AC1PIV_001361"
     CDS             3944..5134
                     /gene="metK"
                     /locus_tag="AC1PIV_001361"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HIP6612381.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAEDPDAHVAAE
                     TAVYTGSVHVFGEISTTAYVDINRVVRDTIAEIGYTKGEYGFSAESVGVHPSLVEQSP
                     DIAQGVNEALETRQDASQDPLDLIGAGDQGLMFGFAVDETPELMPLPISLSHKLVRRL
                     AELRKSGEIAYLRPDAKSQVTVEYDEDNQPVRVDTVVISTQHDPEVSQEQIRQDVIER
                     VIKEIIPAHYLDDQTNYFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAHPVSVRIDTFGTSTVA
                     ESKLEAAVRHIFDLRPAGIIQMLDLKRPIYKQTAAYGHMGRTDIDLPWEKLDKVEALK
                     TAVL"
     gene            5178..5780
                     /locus_tag="AC1PIV_001362"
     CDS             5178..5780
                     /locus_tag="AC1PIV_001362"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008753 - NADPH dehydrogenase (quinone)
                     activity [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0050136 - NADH:ubiquinone reductase
                     (non-electrogenic) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HIP6612382.1"
                     /translation="MSVFAHPRKESFTHALVDRVAEALLENGAEVVIRDLYEIGFDPV
                     LRGEDTIHIEDGKFVRQATVFPADVQVEMDLIAESDLLVYIFPSWWNGMPAIMKGYVD
                     RVFQHGFAYSFESDEPRKLFSTKKAIFFMPTGQPQNADGSLTPIDQAMKTLTSEWLFN
                     SNGAQVIDHIFYGRVPYLTREELELYLVDAREQIQRIFHK"
     gene            5931..7190
                     /locus_tag="AC1PIV_001363"
     CDS             5931..7190
                     /locus_tag="AC1PIV_001363"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HIP6612383.1"
                     /translation="MRKIVINGGKTLKGSVTVSGAKNSVVALIPAIILADGIVTLDGV
                     PAISDVDSLVDIMETMGATVKRDGETLEIDPRGVKDMPMPFGKINSLRASYYFYGSLL
                     GRFGQAVVGLPGGCDLGPRPIDLHLKAFAAMGAETTYEGDYMRLATNGQRIQGAHIFM
                     DVVSVGATINTILAAVKAEGRTVIENAAREPEIIDVATLLNNMGARIRGAGTDIITIE
                     GVDSLKGTRHQVIPDRIEAGTYIALAAAVGEGIRIDNVLYEHLESYIAKLEEMGVRMT
                     ISEDSIFVEKQEKLKAVSVKTSPYPGFATDLQQPITPLLLKAEGTGTIVDTIYEKRVG
                     HVQELANLGAKISTRNNHIAFEGPNQLTGTSVKATDLRAGAAMVIAGLMAQGRTEITN
                     IEFILRGYSNIIDKLTELGADIQLIED"
     gene            7286..7858
                     /locus_tag="AC1PIV_001364"
     CDS             7286..7858
                     /locus_tag="AC1PIV_001364"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIP6612384.1"
                     /translation="MTLWTRLAKFACFETDRLYLRPFSFEDGESFYEIVSNPENLPFI
                     FPALEDRNIAFSTMVEKFMRSPLGNWALVDKYSERMIGALCFEKVDERQLSAELSYFL
                     KKDYWRRGLMTEVVRTLVYLAFYEFGLRELVIVTHEENVASQMVAKKAGLVQVAQYRG
                     SDRYSHKTRNYLKFSLKRAEFSLEMYEENQ"
     gene            7855..8715
                     /locus_tag="AC1PIV_001365"
     CDS             7855..8715
                     /locus_tag="AC1PIV_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HIP6612385.1"
                     /translation="MITIKSQREIDAMNRAGDVLAGIHIGLREIIKPGVDMWEVEEYV
                     RKTCKEKNVLPLQIGVDGELMDYPYATCCGLNDEVAHAFPRHYKLKEGDLLKVDMVLS
                     EPLDKAVVDVSKLNFNDVKAMKKITQTYRGGCADSCWAYAVGQVSEEVQNLMDVTKEC
                     LYRGIEQAVVGNRIGDIGAAIQEYAEGLGYGVVRDLVGHGVGPTFHEEPMVPHYGTKG
                     RGLRLREGMVLTIEPMINTGTWEIDTDMKTGWAHKTLDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            8763..9686
                     /locus_tag="AC1PIV_001366"
     CDS             8763..9686
                     /locus_tag="AC1PIV_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HIP6612386.1"
                     /translation="MKKTKIVEGLKTFCSTFFSFYRSADSDVTSVAVAYYLLISIFPI
                     LLTLANLLPYYPFDVDMILSVVAEFVPDKLYPSVSSFITSVLTKPSSSWLGISILTTL
                     WTLSRSMTILQKAFNKAYGINEHRDFIIGHLIGIFLGIGLQVIILLSITLLTFGQAVF
                     SYINKLVPIEDAWLKGLLSQTQLVGLMALFTALVMLYFFLPNVRIKKVRYVFPGTLFV
                     LLTMTSIGKLFSIYVDNYANKLLDFRIVTAVVFLVFMLWFIFMAQVLIIGAMINATVQ
                     SMQVEEFHARDGDIVSILNRLKARFTAIDKE"
     gene            complement(9733..10170)
                     /locus_tag="AC1PIV_001367"
     CDS             complement(9733..10170)
                     /locus_tag="AC1PIV_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HIP6612387.1"
                     /translation="MKKLFYQLINNEVILYLIAGVAATLVYMVTRMGLFLVIPSILLV
                     TLLANAVAILFAFWTNDRFVFKQAREGWPQRLVKFVSARIATLVMDMALAYLLVQAYP
                     QLIGQFVNHDLTLVNAISTLFSQVLVIVVNYFLSKLFIFKNTK"
     regulatory      10199..10301
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            10299..10814
                     /locus_tag="AC1PIV_001368"
     CDS             10299..10814
                     /locus_tag="AC1PIV_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HIP6612388.1"
                     /translation="MNTSKWTARDMAEIALVAAIYVALTLTPPLNAISFGAVQFRLSE
                     MLNFLAFYNRKYIIAVTIGCMISNLIGFGVIDLFVGGFSTLIFVTLGVILFEKYKKDY
                     LFGGLFNKAFFYFSFFFAATMFTIALELKVLYDLPFFLTWLTTAAGELLSLLVGAVVI
                     DKLSKKINFEK"
     gene            10930..11772
                     /locus_tag="AC1PIV_001369"
     CDS             10930..11772
                     /locus_tag="AC1PIV_001369"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HIP6612389.1"
                     /translation="MTRYTFSNGVTVPKIGFGTWQIPDGEVTYGAVSYALEAGYRHID
                     TAQIYGNEASVGRAIADSGLAREDIFLTTKVWNDKIGYEDTLASVEESMQKLQVDYLD
                     LLLIHWPNPKAVRDSIGWKERNAQVWKALEELYRAGKVKVIGVSNFMEHHLEALLETA
                     EIIPMANQIMLAPGTPQSELVAYCKAKGILLEAYSPFGTGSLFQSQEAADLAKEAGCS
                     VAQLALAWSLDKGFLPLPKSTSPENIKANLEIDGLAISPTAVAKLDKLEGVKGRLDPD
                     QAEF"
     gene            11851..12801
                     /locus_tag="AC1PIV_001370"
                     /pseudo
     CDS             11851..12801
                     /locus_tag="AC1PIV_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002931050.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
     gene            12788..13222
                     /locus_tag="AC1PIV_001371"
     CDS             12788..13222
                     /locus_tag="AC1PIV_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HIP6612390.1"
                     /translation="MDLNKYVQEVSLQDFGKEFRHVAIWNRRLRSTGGRFFPRDGHLD
                     FNPKHLEEQGLEVFRKIVRHELCHYHLYFEKKGYRHGDRDFKELLAAVDGLRYAPQLE
                     QATKPSLIYCCQSCGQVYQRKRRIDLKKYRCGKCRGKLTLKE"
     gene            13292..14053
                     /locus_tag="AC1PIV_001372"
     CDS             13292..14053
                     /locus_tag="AC1PIV_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612391.1"
                     /translation="MTQKREERLIELYEKGVLTKEEARACFKEMNQEPDFLFVEEKVK
                     LNFTLPSFKVFASSKLKQSYSFEGIESLFLKLSEGRLTLAKSKNNQISVEICYNQDAP
                     EDKLPRLYVEKKGLYFHSSLACRLTINLPQEWMSVLDLELGQADARLDYLPFEDISIR
                     SSRDKKQQDIRLTTCGGYPQHLYVQLAQAPLTLQTGKGQGIRGQIESQSGHVLVNRKK
                     KNSPYQFEKSGNDLLFLKVQTGQGGFYVKGIKDVN"
     gene            14043..>14147
                     /locus_tag="AC1PIV_001373"
     CDS             14043..>14147
                     /locus_tag="AC1PIV_001373"
                     /inference="COORDINATES: protein motif:HMM:NF015957.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HIP6612392.1"
                     /translation="MSIELYKVRQGKIVSGVLAGIAHKLVWESWVTRAI"
BASE COUNT         3935 a         2572 c         3417 g         4223 t
ORIGIN      
        1 agaaagcacc aattagattg gtgttttctt gtttagaaaa gaatcgaaac ctatcaagaa
       61 agcatataaa aattcagcca gttgactgaa tttttggtat aatctatttt atgaaacttc
      121 cacaatttct ttttttagcc attacaacta ttttagctgt ttattttatg aatgcatcga
      181 ttttgacagg agatttcttg attgcaggta tctacgcctt tatcgcctat cggaatcttc
      241 attttgctta caaggtgact aaatttattc gtttggtgga gaagcagacc aagaagtaag
      301 gctgatttct ccgctggaga taatttttgc tttgccgtta tctaactgga taaccaggtt
      361 tcctgtatca gtaacagcga tggcagtacc cttaaattca acttgatttt ctacaaagct
      421 cacttgttgg ccaacgacaa gtgatttttc tttgtaaagg gcaattagtt ccttctcatc
      481 ggtttctaag aaggctttcc agatggcagt aatgagttgg ttgcgggtaa atggtggttg
      541 ttcctcgaaa agatttcctg cagattgttg taattcctta gggaaatcgt ctatgcggac
      601 attgatgccg acaccgataa tgacatcggt tacccgttgg ttttccatgg aagagatagc
      661 ctcagtgagg atgccagcga cctttttgtg tccgagatag atgtcattga cccacttgat
      721 ttggacgtcc aagtcgcaaa gagattgaat ggccttcaca acagcagctg cagctaaaat
      781 ggtgtagggc ttaaattcta gaaatggaac attgggagag agacgaagcg acatataaat
      841 accacctgac ttggaggcat aaaagggtct cccaaatcgt cccttggctt tattctgata
      901 gggagctaga tatagggcag gactagtatg acctgattca ataccttgtt tggcatctag
      961 ctgggtggag tcgctatcca tattcagatg gacaggtagt tgaagctcct gagagattaa
     1021 ttcgggtagg agtaaatcgc cttcggctaa tctgtagcca cgattacggg cagcctcaat
     1081 agttaaacca tgcgtttcta actggcgaat ggccttccaa atggatgtcc gtgaaatgcc
     1141 caattcctgt gccaaatctt ctccgctgac ataatcctct ctctctttta aaaggagata
     1201 tattttctga taggttttca taccttcatt atagcaaaaa aatcacctaa aacgtgatat
     1261 aatagtttta aataaggagg ttttcatgaa gacacttgat tacattgtta cattgaccaa
     1321 cactccgtcg ccaactggtt ttacgacgga tattatgaat tatatcaagg cagaggttga
     1381 aagtttcggc tatgttgcta gtaagaccgc taaaggtggt gttttggtga cagttccggg
     1441 ggaaaatgat caggaacacc gtatggtgac tgctcacctg gacacactgg gggccatggt
     1501 tcgtgcagtg aaaccggatg gccgactcaa aatggatttg gtgggaggat ttggataccc
     1561 ttctattgag ggagaaaact gcttaattca ttgcgctaaa aatggcaaga ctttcacagg
     1621 tactattctc atgcaccaga cctctgtcca tgtctatcgg gatgccagta ccgctgagcg
     1681 caatcagacc aacatggaaa ttcgtttgga cgaaaaagtg accaatgcgg acgagacgca
     1741 ggccttaggt attgaagtcg gagattttat ctcctttgat cctcgtaccg tcgtgacaga
     1801 aactggcttt atcaagagtc gtcccttgga tgataaggta tccgcagcta tcttgctcca
     1861 tctattgaag gtctataagg aagagggagc gaccttgcct tatacgacac atttctattt
     1921 ttcaaacaat gaagagattg gctacggtgc caactccagc attcctgctc aggtggttga
     1981 atatttggca gtcgatatgg gggcaatggg agatgaccag cagacggatg agtacacggt
     2041 ttctatctgt gtcaaggacg gatcaggtcc ctaccattat gaacttcgtc agcacttgat
     2101 agccttggct gaaagagatg gaattcctta taagctggat atttatcctt actatggttc
     2161 cgatgcttcg gcagctatgc gagcaggtgc agatgtcaag catgcactgc ttggtgctgg
     2221 cattgagtct agccattcct atgaacggac gcatttggat tctgtagttg cgactgagcg
     2281 gatggtagat gcctatttga aatcagcaat ggtagattaa gatgaatgaa acccgttttt
     2341 tagagttatt caatgacttg gataaggtct tgcgtaaggt gtgcggtgtt gcggatgggg
     2401 aatatgcaga tgtaggctct atgttgacca aagcaaagga attgacgcga cataatcccg
     2461 ttgaggcgaa ctgggataaa ctctatgtgg ctcgtcagtt gcgtaatctc atggttcatg
     2521 agaaacgaac aggtttgaag gaagtagccc aaccttcgca ggaattgatc actgttttgg
     2581 aaaaagtgat agcccagtac caagaaccga ttaccattgc cgactatttg caaaagaccc
     2641 agaaaattaa gccggttatt tttgagggca aggacaaatt gacaaaggct ttagaaattg
     2701 tggagcaaga gcatttttct aagtttccta ttttttctga caaggtttat caaggcctgg
     2761 tttctgacaa gggattgaca aattggttgg ccaaggcaag caaggaaacg ggctctatac
     2821 gtgaaaaatt ggtggaggct agtcttgaag acgtactagc ttgtgaggaa gatagtattc
     2881 aggtgattgt tctaccaata acagcccatc tttatcaggt aattaatcat tttgaagggc
     2941 gtaagcgcac aaccgtccta gtcagtcgtc aggcgagtgg gaagcttcat tcgccagagg
     3001 atcttgttgg tattgtcaca gcacaggact tggcagagat ttatgggatg gtggattgag
     3061 tggagaaagg agaaatcatg tcaacaaatc gtttagcttg ggatgagtat tttgcggctc
     3121 aggcgctttt gattgccaat cgggcgacct gtaagagagc aaaagtcggt gcggttttgg
     3181 ttaaggacaa taaggttatc gcaacaggct acaatggttc tgtttcagga accgaacatt
     3241 gtttggatca ggaatgcctt atgattgatg gtcattgtgc tagaaccttg catgcggaag
     3301 tcaatgccat tttacaagga gcggagcggg gaattccaaa aggttttact gcctatgtga
     3361 ctcattttcc ctgtctcaac tgctctaagc aattgttaca ggttggttgt aagcgggttg
     3421 tctatatcaa tgaataccgc atggatgact atgctcagta cttgtataaa gaaaagggct
     3481 gtgagttggt tcatttgcct ctagaggtgg ttaaacaggc atttgcagat gccgaattta
     3541 tctaatgatt ttgtagaaga gtggttgcat agaacaaccc tctttatttt taagaaaatg
     3601 ctaggatagt cggtcaatct atgctatact agaaacgtta ttaagtcccg aaaaggtagt
     3661 ttatagacta gttaatattt gcagaaacac ttgaaacaca attaaagaaa ctggtaatat
     3721 tgaatagtaa gcgtaaaaac tttactacac ttcagtcact attttcttca aagctaggct
     3781 actctcatat agtctggtat tgtctttctc gttgggtatc tggaaatttc cctttgctta
     3841 agacagttgt ctttcgcaaa gaactagtct ttgactagtt ctttgtaacc ttagtaaccc
     3901 gctaggtttc tagcatatat tctattttaa gggggacatt tttatgtcag aacgtaagtt
     3961 gtttacgtct gaatctgttt cggagggtca tccggataag attgcagacc agatttcaga
     4021 tgccattttg gacgctattt tagcagagga tccagatgcg cacgtagcgg cagagacggc
     4081 tgtttataca ggtagtgttc atgtgtttgg agagatttca accactgcct atgtggatat
     4141 taaccgtgtg gtacgggata cgattgcgga gattggctat acaaaaggtg agtatggttt
     4201 ttcagctgag tcggttgggg ttcatccgtc acttgtagag caatcgccag atattgccca
     4261 aggcgtcaat gaagccttgg aaactcgtca agatgctagt caagatccat tggatttgat
     4321 tggtgcaggt gaccaggggc tcatgtttgg ttttgcagta gatgaaacgc ctgaacttat
     4381 gccgttgcca atttcactta gtcacaaatt ggtgcgtcgt ttggccgagt tgagaaaatc
     4441 tggtgaaatt gcttatctcc gtccagatgc taagtcacag gtaacagttg aatacgatga
     4501 agataatcaa cctgttcgtg tggatacagt cgttatttcg acccagcatg atccagaagt
     4561 tagccaggag caaattcgtc aggatgtcat tgaacgtgtg attaaggaaa tcattccagc
     4621 tcattatctg gatgaccaaa ccaactactt tatcaaccca actggtcgct ttgtcattgg
     4681 cggacctcaa ggggactctg gtttgacagg ccgtaagatt atcgttgata cctatggtgg
     4741 ttattctcgt catggcggcg gtgccttctc tggtaaggat gcgaccaaag tggaccgttc
     4801 tgcatcttat gcggcacgct acatcgcaaa aaatatcgtc gcagctggtt tggctaaaaa
     4861 ggcggaagtt caattggctt acgctatcgg tgttgctcac ccagtttcag ttcgcatcga
     4921 tacctttggt acgagcacag tagcggaaag caagctagaa gcagctgttc gtcatatttt
     4981 cgatttgcgc ccagctggta ttatccagat gttggatctt aagcgcccga tttacaagca
     5041 aactgcagcc tatggacaca tgggacgtac cgatattgat ctcccatggg agaaattgga
     5101 caaggtggaa gccttgaaaa ctgcggtttt gtaatgaaat agttgtccac ttagtgagaa
     5161 gtttatgaaa gcgttaattg tctgtctttg cacaccctag aaaagaaagc tttacacatg
     5221 ctttggttga tagagtggcg gaagctctgc tagaaaatgg agcagaagtt gtcatccgag
     5281 atttatacga aataggattc gatcccgtgt tacgtggaga agataccatt catattgagg
     5341 atggtaaatt tgtacgtcag gcaactgttt ttccagcaga tgttcaagtt gaaatggatt
     5401 tgattgccga aagcgactta ctagtctata tatttccgag ttggtggaat ggaatgcctg
     5461 ctattatgaa aggttacgta gaccgtgtat ttcaacatgg ctttgcttac agttttgaat
     5521 ctgatgaacc acgtaaatta ttttccacta agaaagctat tttctttatg ccaacagggc
     5581 agccacaaaa tgcagatgga agtctgacac cgattgatca agcgatgaaa accctgacct
     5641 cagaatggct cttcaatagc aacggtgctc aagtcattga ccatatcttc tatgggcgag
     5701 taccttattt aacgagagaa gagctggagt tgtatctcgt ggatgcaagg gagcaaattc
     5761 agagaatttt tcataaatga tgaagagaga ttcactaatc gtatataaat atgaaggact
     5821 gagctcattg gctcggtcct tttgcatgct atataactag ctttttccaa gactttatga
     5881 tagaatgaaa cgtatgcctt tttaggcaaa ttaagaaagt gaatgttagt atgagaaaaa
     5941 ttgtaattaa tggtggaaaa acactgaaag ggtcggttac cgttagtggt gcaaaaaact
     6001 cagttgttgc tcttattccg gccattattc ttgcagacgg gattgttact ctggacggag
     6061 tacctgcaat ctcggatgta gatagcttag ttgatattat ggaaacaatg ggcgcgacgg
     6121 tcaagcgtga tggtgaaacc ttggagattg accctcgtgg tgtaaaagac atgcctatgc
     6181 catttggcaa aattaatagc ttgcgtgcat cctactattt ttacggttcc ctccttggtc
     6241 gctttggtca agctgttgtt ggcttgccag gtggttgtga tttgggaccg cgtccgattg
     6301 atttgcactt gaaagcattc gcggcaatgg gagctgagac aacctatgaa ggtgactata
     6361 tgcgcttggc aactaatggt cagcgtattc aaggggcaca tatcttcatg gatgttgtca
     6421 gcgtcggtgc gacaattaat actatcttag cagctgtcaa agcagaaggc cgtacagtta
     6481 ttgaaaatgc ggcgcgtgaa cctgaaatta ttgatgtggc aactttgctt aataatatgg
     6541 gggcacgtat ccgtggtgcg ggtacagata ttatcaccat tgaaggcgta gatagtctaa
     6601 aaggaacacg tcatcaggtg attccagacc gtattgaagc agggacttat attgcccttg
     6661 ctgctgctgt tggtgaaggt attcgtatcg ataatgtcct ttatgaacac ttagagagtt
     6721 acatcgctaa gttggaagaa atgggtgttc gcatgaccat ttctgaagat agtatttttg
     6781 ttgaaaagca agagaaattg aaggcggtaa gtgtgaaaac ttcaccttat ccaggttttg
     6841 cgacagactt gcagcaaccc attactcctt tactgcttaa ggcagaaggg actggtacga
     6901 ttgttgatac gatttatgaa aaacgtgttg gtcatgtgca ggagcttgca aatcttggag
     6961 caaaaatctc tactcgtaac aaccatattg cctttgaagg tccaaatcaa ctgactggta
     7021 catctgttaa agctactgat ttgcgtgcgg gagccgcaat ggttatcgct ggtttaatgg
     7081 ctcaagggcg tacagaaatt acaaacattg agtttattct acgtggttac tcaaatatta
     7141 ttgataaact gacagaattg ggtgcagata ttcaattgat tgaggattag agagtctaat
     7201 tgagaactac tttctcaaaa cgtaatcgat ttaaaaaacg aaacaatctg gggctgggag
     7261 taattctcag ccccttgggt acactatgac actttggaca agactagcga agtttgcttg
     7321 ctttgaaacg gaccgtttgt atttacgacc attttctttt gaagatggag aaagtttcta
     7381 tgaaattgta tcaaatcccg aaaatcttcc ttttatcttt ccagctttgg aggacagaaa
     7441 tattgctttt tcgacaatgg ttgaaaaatt tatgcgttca ccattgggaa actgggcctt
     7501 agttgataag tattcggaga ggatgattgg tgcgctttgc tttgaaaagg tagatgaacg
     7561 tcaactttct gcggagctca gctatttcct aaaaaaagac tactggagaa gaggcttaat
     7621 gacggaagta gtgaggactt tagtctatct agctttttat gagtttggtc tgagggagct
     7681 ggttattgtc acccatgagg aaaatgtggc cagtcagatg gtggcgaaaa aagctggttt
     7741 ggtacaggtt gcgcagtatc gcggaagtga ccgctatagc cataaaacaa gaaattatct
     7801 aaaatttagc ttgaagaggg ctgaatttag tttagaaatg tatgaggaga atcaatgatt
     7861 accattaaat cacaacgaga aattgatgca atgaaccgtg ctggagatgt tctggctggt
     7921 attcatattg gtttgcgaga gattatcaag ccaggtgtgg acatgtggga agtagaggaa
     7981 tatgtccgta aaacgtgtaa ggaaaagaat gttttgccac tccaaattgg tgttgatgga
     8041 gaattgatgg attatcctta tgcgacttgt tgtggattga atgacgaggt cgctcatgct
     8101 tttccgcgtc attacaaact taaagaaggt gatttactga aggtcgatat ggttttgagc
     8161 gagcctttgg ataaagcggt agttgatgtt tctaagctca actttaatga tgtcaaggct
     8221 atgaagaaaa tcacccagac ctatcgtggt ggttgtgcgg attcctgctg ggcttatgcg
     8281 gttggtcagg tctctgagga agttcaaaac ttgatggacg tgactaagga atgtttgtat
     8341 cgtggtatcg agcaagcagt tgttggcaat cgtatcggcg atatcggtgc tgccattcaa
     8401 gaatatgcgg aaggtcttgg ctacggtgtt gttcgtgact tggtagggca cggcgttgga
     8461 ccaaccttcc acgaagagcc gatggttcct cattatggaa ctaaaggtcg tggtcttcgc
     8521 ttgcgtgaag gtatggtttt gactatcgag cctatgatta atacaggtac ttgggaaatt
     8581 gatacggata tgaagactgg ttgggctcat aagacacttg atggtggttt gtcttgtcaa
     8641 tacgaacacc aatttgtcat caccaaagat ggaccggtta ttttgaccag tcaaggtgaa
     8701 gaagggacct attaattctc ggtgtggtcg tgaataatag atgaatgagg aaggaggaga
     8761 gaatgaagaa aaccaaaata gttgaaggtt tgaaaacatt ctgctcaacc ttcttttctt
     8821 tttatcgttc tgctgatagc gatgtaacaa gcgttgcagt agcttactat ttgttaattt
     8881 ctattttccc tattcttcta actctcgcga atttactgcc atattatcca tttgatgtgg
     8941 atatgatttt atcggttgta gctgaatttg tgccagacaa gctctatcct tcggtttcat
     9001 cttttatcac ttctgtatta acaaagccgt cgtcatcgtg gttagggatt tcaattctga
     9061 caactctttg gaccctgtca cgtagtatga ctattttgca gaaggccttt aataaggctt
     9121 atggtatcaa tgaacaccgt gattttatta ttgggcactt gattggcata tttttaggaa
     9181 ttggtctgca ggtaattatc ctcttaagta ttacgctttt gactttcggg caggcagttt
     9241 tttcttatat taataagctg gttcctattg aagacgcctg gctgaagggg cttcttagtc
     9301 aaacacagtt agtaggttta atggctctgt ttaccgcctt ggttatgctt tatttctttt
     9361 tgccaaatgt tcggataaaa aaagttcgat atgtttttcc aggaacgtta tttgttctgt
     9421 tgacgatgac ttctattgga aagttatttt cgatttatgt tgataattat gctaataagt
     9481 tgctggattt tagaatagta acagctgtcg tctttcttgt ttttatgctt tggttcattt
     9541 ttatggctca ggtactcatc attggtgcaa tgattaatgc tacggttcaa agtatgcagg
     9601 tagaagagtt tcatgccaga gatggggata ttgtttctat cttgaatagg ctaaaggcaa
     9661 gatttacagc gatagataaa gaatgaagta ggaaaatcaa gctatatata aaaatgaggt
     9721 tccgttggag cctcatttcg tatttttaaa gataaagagt ttgctcaaga aatagttgac
     9781 cacaatgacc aagacttgag agaagagagt ggaaatggcg ttgacaagtg tcaaatcatg
     9841 gttgacaaac tgcccaatca attgtgggta ggcttgtact aataaatagg ctagagccat
     9901 atccatgacc aaggtcgcga tgcgggcaga tacaaacttg accaatcgct gaggccaacc
     9961 ctctctggct tgtttgaaaa cgaaacggtc gttggtccaa aaggcaaaga ggatagctac
    10021 tgcattggct aaaagagtaa ccaatagaat ggaaggaatg actaaaaata gccccattcg
    10081 agtgaccata tagacaaggg ttgctgccac acctgcaatc aaatagagaa taacttcgtt
    10141 attgatgagt tgataaaata gttttttcat aggactagtc tatcattttt agcaaaaata
    10201 tgctatacta atcaacgttg ttgataaatt caatgaccct tggggcttgc tcactttacc
    10261 caagcatatt ttaagctttt tcgctaaagg agaattttat gaatacatct aaatggactg
    10321 ccagagatat ggcagaaatt gctcttgttg cggcgattta tgtcgctctt accttgacac
    10381 cgccattgaa tgctatttcc ttcggggctg ttcagtttcg tttgtctgaa atgctcaatt
    10441 tcttggcttt ttataatcgt aagtatatta tcgccgtgac cattggctgc atgatttcta
    10501 acttgattgg ttttggtgtg attgacctct ttgtgggtgg attctcgaca ttaatcttcg
    10561 ttacattggg agttatcctg tttgaaaaat acaagaagga ctatctattc ggtggattat
    10621 ttaacaaggc tttcttttat ttctcattct tttttgcggc aactatgttt accattgctt
    10681 tagaattaaa agtcttatat gatctaccat tctttctaac ttggttgaca acagcagcag
    10741 gagaattgct ttctctatta gttggagctg ttgttatcga caaactatcc aagaaaataa
    10801 attttgaaaa gtaagtatac aataaatgtg agcagacact ttcgggtgtc ttttattttt
    10861 aggtcgcatt attttgtatt gattgacaat ttagtttata ctggggatag aagaaatagg
    10921 aggtctttta tgacaagata tacgttttca aatggtgtaa ctgttcctaa aattggtttt
    10981 ggaacttggc agatacccga tggtgaagtg acgtacggtg cggtttctta tgcattggaa
    11041 gctggttatc gtcacattga cacggcacag atttatggca acgaagctag tgttggtcga
    11101 gctatagctg atagtggtct agctcgtgag gacatttttt taacaactaa ggtttggaat
    11161 gacaagattg gctatgaaga tacccttgct tcagtagaag aatccatgca aaaacttcag
    11221 gtggattatc tggatttgtt actgatccat tggccaaatc ccaaggctgt tcgcgacagc
    11281 attggctgga aggaacgcaa tgcccaggtt tggaaggcat tagaagagct ctatcgtgct
    11341 ggaaaagtga aagtaattgg agtttctaac tttatggaac accatctaga agctttgctg
    11401 gaaacggctg agattatccc gatggctaat cagattatgc tggccccagg aactcctcag
    11461 tcagaattag tggcctactg caaagccaaa gggattctct tggaggccta tagcccattt
    11521 ggtacaggaa gccttttcca aagccaagaa gcagccgatt tggctaaaga agctggttgt
    11581 agtgttgccc agctggcact agcttggtct ttagataaag gttttctccc tctcccgaaa
    11641 tcaactagtc cagaaaatat taaggcgaat ttggaaattg atggcttggc tattagtccg
    11701 acagcagttg caaagttgga taaactagaa ggagtaaaag gtcgacttga cccggatcag
    11761 gctgaatttt aattagctat tgagagcatg tagtttatct acgtgctttt tctattgagc
    11821 catttgtacc gctttcatgc tataatagta gcttctgtct actcagcttc tgaactggcg
    11881 cgatatgagt ttccagacct ccctgtggaa aaacgctctg ccatttccat cgcccgccgt
    11941 ctgcaagacc ctctggctga gctggtcaaa attgatccca agtctatcgg tgtcggccag
    12001 taccagcacg atgtcaacca gaagtctctg tctgaaagtc tggattttgt ggtcgatacg
    12061 gtggtcaacc aggtcggtgt caatgtcaat acggccagtc ctgccctttt ggctcacgtt
    12121 gctggtctta acaagaccat ttcggagaac atcgtcaagt accgcgagga aaacggtgct
    12181 ctgacctctc gtcagcaact caaaaaggtt ccacgtttgg gtgacaaggc ctttgagcag
    12241 gcagctggtt tcttgcggat tcctgatgcg actaactttt tggacaatac tggcgtgcac
    12301 cctgagtctt acaaggctgt ggaaaatctg ttagaacttc tagctattga ccacttagat
    12361 gaggctgcgc aggaaaaatt gaagcagctt gccatcgcag atacggcaga aaaaatcggt
    12421 gtcggtcaag aaacattgaa ggacatcatc gcagacttgc tcaaacctgg tcgtgattta
    12481 cgggatgact ttgaagcacc agtccttcgt caagatgtct tggatgtcaa ggacctggta
    12541 gtcggacagg aattgcaagg tacggtccgc aatattgtgg actttggagc ctttgtggac
    12601 atcggtgtcc acgaggatgg tctggtccac atttcacgca tggtcaaacg caaacgagat
    12661 aaaaatggac gccaacaagc cttgccacat ccaagcgaag ttctcgcagt tggggaaatc
    12721 gtaaccgtct gggtggttga agtggacatc aaacgaaatc gtatcggtct tagccttttg
    12781 aaaccaaatg gatctgaata agtatgtgca agaagtctcc ttgcaagact tcggtaagga
    12841 atttcggcat gtagcaatct ggaacaggcg attacgctca acaggtggtc gcttttttcc
    12901 aagggatggg catttggatt tcaatcccaa gcatttggag gagcaaggtt tagaagtctt
    12961 tcggaagatt gtccgccacg agctctgcca ctaccatctc tactttgaga agaaaggcta
    13021 tcggcatgga gacagggatt ttaaagaatt gctagctgcg gtggatggcc tgcgctatgc
    13081 tccccaactg gaacaagcta ctaagcctag tctgatttac tgctgtcagt cctgtggaca
    13141 agtctaccag cgcaagcgcc gcattgacct aaaaaaatac cgatgtggga agtgtcgggg
    13201 taaacttact ttgaaagaat agagaatcag tcttcgggct gatttttttg tggagaaatg
    13261 tgatatacta gagtagaatt gaggtgagtc tatgacgcaa aagagagaag aacgcttaat
    13321 tgagttatat gaaaaaggtg tcttgaccaa ggaagaggcg cgtgcctgtt ttaaggaaat
    13381 gaatcaagaa ccagactttc tttttgtgga agaaaaagta aaattgaatt ttaccttgcc
    13441 aagttttaag gtctttgctt cctccaaatt gaaacaatcc tatagttttg aagggattga
    13501 atcactcttt ttaaaattat ctgagggacg tctaactttg gctaagtcta aaaataatca
    13561 gattagtgtg gagatttgct acaatcaaga tgcaccagaa gataagcttc ctcgtcttta
    13621 tgttgaaaaa aaggggcttt attttcacag tagcttggcc tgtcgtttga caatcaactt
    13681 gcctcaggaa tggatgtcgg tgctggattt ggaacttggt caggcagatg ctcgcttgga
    13741 ttacttacca tttgaagata tttctatccg cagttcaagg gataaaaaac aacaggatat
    13801 tcgcttgacg acttgcggtg gttatcccca acacttgtat gtgcaactag ctcaggctcc
    13861 cttgacttta caaactggca aaggccaggg aattcggggg cagattgagt cgcaatcagg
    13921 tcatgtcttg gttaaccgga aaaagaaaaa tagtccctat cagtttgaaa aatctggcaa
    13981 tgatttactt ttcttgaagg tacaaacagg tcaagggggc ttttacgtga aaggaataaa
    14041 agatgtcaat tgaattatat aaagtaaggc aggggaagat agtatctggg gttcttgccg
    14101 gcatagcgca taaattggtc tgggaatcct gggtaacacg cgcgata
//
LOCUS       DBNFCO010000052        13732 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.052, whole genome shotgun sequence.
ACCESSION   DBNFCO010000052 DBNFCO010000000
VERSION     DBNFCO010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 13732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13732
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.052"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(22..1899)
                     /locus_tag="AC1PIV_001374"
     CDS             complement(22..1899)
                     /locus_tag="AC1PIV_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose PTS transporter subunit IIA"
                     /protein_id="HIP6612393.1"
                     /translation="MNNTEIAKKVIDALGGRENVRSVAHCATRLRVMVVDEGKIDKDT
                     VEDIEKVQGAFFNSGQYQIIFGTGTVNKIYDEVVALGLPTATTGEQKAEAAKQGNAFQ
                     RAIRTFGDVFVPIIPAIVATGLFMGLRGLLGALGYTLPEDLNVYSQILTDTAFIVLPA
                     LVVWSTFRVFGGNQTIGIVLGMMLIAGQLPNAWVVASGGDVKPTIFFGFIPVVGLQGS
                     VLPAFIIGLVGAKFEKAVRKVVPEVLDLLVTPFVTLFVMSILGLFVIGPVFHVVENYI
                     LAGTQAILNLPMGLGGLLIGGVHQVIVVSGVHHIFNFLEAQLVANTGANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKALAFPAALSAFLGITEPAIFGVNLRFRKPFLLSLIAG
                     AIGGAVASLLGLAGKGMGVTIIPGATLYVGNGQLFQYILMVAVSFALGFALTYLFGFE
                     DEVEAAPKAAAAPVATPATPAVELNEETLVSPLSGDVVALENVNDPVFSSGAMGKGLA
                     VKPSEGVVYAPADAEVTIAFETGHAYGLKTASGAELLIHIGIDTVSMNGNGFEKLVAA
                     GDKVKAGTPLAKFDAAKIAEAGLDDTTMIIVTNTADFAEVSPLAEGTIAHGVEFLKVA
                     K"
     gene            2105..3559
                     /locus_tag="AC1PIV_001375"
     CDS             2105..3559
                     /locus_tag="AC1PIV_001375"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004564 - beta-fructofuranosidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HIP6612394.1"
                     /translation="MAFTTGERYRAYADWTPEYIEKIKKNTESSPWRTNFHIETPHGL
                     LNDPNGFSYFNGKWTLFYQYFPFGAAHGLKSWVHTESTDLVHFEETGTVMYPDTPLDS
                     HGAYSGSAMEFGDKLFLFYTGNVRDENWVRHPYQIGALMDKDGKIEKIDKVLIEQPED
                     TTDHFRDPQIFNYKGQYYAIVGGQNLDKKGIVKLYKAENNDYLNWSYVGDLDFANDMT
                     AYMMECPNIAFVGEQPILLYCPQGLDKEVLDYGNIYPNMYKIGQSFVPETASIVEPSE
                     LINLDYGFECYATQAFNAPDGRTLSVSWLALPDVEYPTDAYDYQGCLSLVKELTIKDG
                     KLYQYPVDAITSLRKEAQPFSAQKETNNVYELELDFSASTKHEIVLFANEAEKGLVLS
                     VDTEQGQITLDRGNCGQPFALDFGTSRSCEISPGALTANIFIDKSVFEIFINKGEKVF
                     SGRVFPDADQSGIVITTGNPTGTYYHLDYGRKTN"
     gene            3540..4505
                     /locus_tag="AC1PIV_001376"
     CDS             3540..4505
                     /locus_tag="AC1PIV_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HIP6612395.1"
                     /translation="MVAKLTDVAQLAGVSPTTVSRVINKKGYLSEKTIRNVEEAMREL
                     GYKPNNLARSLQGKSAKLVGLIFPTINNIFYSELISHLEKELFDRGYKTIICNSQHES
                     DKEREYLEMLAANQVDGIISGSHNLGIQDYDRVVAPIIAFDRNLSPSIPIVSSDNFAG
                     GVLAAQTLQKAGCHNPLMITGNDDSNSPTGLRQVGFTSILNKAEVFHISSDFSPVRKE
                     MEIRAILEKQKPNGIFVSGDATAMLVWNVIRSMKLSIPEDIKLIGYDGTSFIENYYPQ
                     LTTIKQPLTEIARLLVELLVDKIEGKKLTKTDYILPISLLAGASI"
     gene            complement(4585..5004)
                     /gene="nusB"
                     /locus_tag="AC1PIV_001377"
     CDS             complement(4585..5004)
                     /gene="nusB"
                     /locus_tag="AC1PIV_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HIP6612396.1"
                     /translation="MKNNRHALRKCALQAIVSLEFGQEPVQAAQFSYLYDREEEQEGV
                     EIPLFLLNLVNGVADYRDDLDKELSSRLKAGWTLDRLTLIDKNIMRLGLFEILHFEET
                     PDRVAVNEAIELAKEFSDESSAKFVNGVLSQFIKEEA"
     gene            complement(4994..5386)
                     /locus_tag="AC1PIV_001378"
     CDS             complement(4994..5386)
                     /locus_tag="AC1PIV_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HIP6612397.1"
                     /translation="MTTEYQGEIVIAPRVLEVITGIAAAKVDGVHSLQNKRVADSWSK
                     TSLNKGVYLETDEEGRVTADIYVYLEYGVNVPAVSMDIQRAVKTAVYNYAEVQVAAVN
                     IHVSGIVPDKTPKPALKDLFGEDFLDEE"
     gene            complement(5414..5971)
                     /gene="efp"
                     /locus_tag="AC1PIV_001379"
     CDS             complement(5414..5971)
                     /gene="efp"
                     /locus_tag="AC1PIV_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HIP6612398.1"
                     /translation="MIEASKLRAGMTFEAEGKLIKVLDASHHKPGKGNTIMRMKLRDV
                     RTGSTFDTTYRPDEKFEQAIIETVPAQYLYQMDDTAYFMNTETYDQYEIPVATIKEEL
                     LYILENSEVKIQFYGTEVIGVTVPTTVELVVAETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIEAGQKLVINTAEGTYVSRA"
     gene            complement(6035..7096)
                     /locus_tag="AC1PIV_001380"
     CDS             complement(6035..7096)
                     /locus_tag="AC1PIV_001380"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HIP6612399.1"
                     /translation="MQKRLEKFEAKLAQSTVDGILVTGQNNIYYLTGFWGTEATVFIS
                     GKRRLFVTDSRYTLIAKASVKGFDIIESRFALEEIAKVIKEDGLEKIGFDSEVTYGFY
                     QSLTSIFEGYQLVAMSNFIEDLRMIKDEKEIATIRRACQISDQAFIDVLDFIKPGQTT
                     EMDVNHFLDHRMRQLGAEGASFEFIVASGYRSAMPHGRASEKVIQSGETLTLDFGCYY
                     QHYVSDMTRTIHIGHVTDQEREIYDVVLRANKALIEQAKEGVTYREFDAIPREIISAA
                     GYGANFTHGIGHGIGLDIHEYPYFGKSDETIKAGMVLTDEPGIYLDDKYGVRIEDDLL
                     ITENGCEVLTLAPKELIVI"
     gene            complement(7195..10020)
                     /gene="uvrA"
                     /locus_tag="AC1PIV_001381"
     CDS             complement(7195..10020)
                     /gene="uvrA"
                     /locus_tag="AC1PIV_001381"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HIP6612400.1"
                     /translation="MQENIVIHGARAHNLKNIDVTIPREKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMDKPDVDSIEGLSPAISIDQKTTSRNPRSTVGTA
                     TEINDYLRLLYARVGVPYCINGHGAIAASSVEQIVDEVLELPERQRLQILAPIVRKKK
                     GQHKTIFEKIQKDGYVRVRVNGGVYDVSEVPELSKSKAHNIEVVVDRIVIKDGIRSRL
                     FDSIEAALRIADGYVIIDTMDEKEMLFSEYYACPVCGFTVPELEPRLFSFNAPFGSCS
                     DCDGLGMKLEVDTDLIVPDASKTLREGALAPWNPISSNYYPQMLEQAMNHFGVDMDKP
                     FEELTEEEKNLIFNGSDGKEFHFHYENEFGGVRDIDIPFEGLITNINRRYRETNSDYT
                     RTVMKTYMNELTCGTCHGYRLNDQALSVKVGGEQGLHIGQLSDLSVADHLQVIEHLTL
                     SENEATIATPIVKEIKDRLSFLNNVGLNYLTLSRAAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADWLIDIGPGA
                     GVFGGEIVASGTPAQVAKNKKSITGQYLSGKREIPVPLERRVGNGRFLEVTGAKENNL
                     QDVTVRFPLGKFVAVTGVSGSGKSTLVNSILKKAIAQKLNRNSDKPGKFKSISGIEHL
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVFVPCEVCHGHRYNSETLEVHYKEKNIAQVLDMTVNDAVE
                     FFKHIPKIERKLRTIQDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSLYIL
                     DEPTTGLHTEDIAQLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDMGPEGGVGGGT
                     VVATGTPEEVAENPASFTGQYLKMKLK"
     gene            10524..11468
                     /locus_tag="AC1PIV_001382"
     CDS             10524..11468
                     /locus_tag="AC1PIV_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HIP6612401.1"
                     /translation="MKQIFLSTMTDLEEIQTFEPGAWINLVNPSQSESMEVAEHYKID
                     IADLRAPLDAEESSRITVEDDYTLILVDVPILEERNNKTYYITIPLGIILTDDAIITT
                     CLEPLPLFEQFIHRRLRNFFTFMKSRFVFQILYRNAQLYLSALRTIDRKSEEIEKQLH
                     EATRNEELIVLMELEKTIVYFKASLKTNERLVKKLASSSRLLRKYEEDEDLLEDTLVE
                     TQQAIEMADIYGSILNSMTHAFASIISNNQNTIMKTLALVTIVLSIPTMVFSAYGMNF
                     KDNIIPFNDIPYAFWWIILFAFAISLSLTFYFIRKRWF"
     gene            11484..12140
                     /locus_tag="AC1PIV_001383"
     CDS             11484..12140
                     /locus_tag="AC1PIV_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HIP6612402.1"
                     /translation="MSFTEINGLTKKNQEFIHIATNQLIKDGKSDSEIKELLEEILPT
                     IIEKQKTGVTARNLYGAPSEWAASKTISEQEKKDQVEYNENPWLMWLDSSLFMLAIIA
                     GINGLMNLFGQGAQYGLLTLFVIGFGVGAGMYLMYHFVYREQIKTGQRPKLLKAIAFL
                     GLATLAWSVVFILAALIPAAFNPVLPPLVTILIGAAAFGARYLLKKKYNIRNAMSPVQ
                     "
     gene            complement(12530..12769)
                     /gene="rpsR"
                     /locus_tag="AC1PIV_001384"
     CDS             complement(12530..12769)
                     /gene="rpsR"
                     /locus_tag="AC1PIV_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HIP6612403.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFISERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALLPFVNED"
     gene            complement(12802..13296)
                     /locus_tag="AC1PIV_001385"
     CDS             complement(12802..13296)
                     /locus_tag="AC1PIV_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HIP6612404.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNQAVATFTLAVNRNFKNQNGER
                     EADFINVVIWRQQAENLANWAKKGALIGVTGRIQTRSYDNQQGQRVYVTEVVAESFQL
                     LESRTAREGQGGGYSAGNSFAGGNDYNSPYQAPAQSTPNFAREESPFGASNPMDISDD
                     DLPF"
     gene            complement(13308..13598)
                     /gene="rpsF"
                     /locus_tag="AC1PIV_001386"
     CDS             complement(13308..13598)
                     /gene="rpsF"
                     /locus_tag="AC1PIV_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HIP6612405.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATIVESKAWE
                     KRRLAYEIKDFREGLYHIVNVEANNDEALKEFDRLSKINGDILRHMIVKLDA"
BASE COUNT         4004 a         3140 c         2726 g         3862 t
ORIGIN      
        1 acaaatcgat tttatataag attacttagc tactttcaag aattctacac cgtgagcgat
       61 tgttccctct gcaagtggag atacttctgc aaagtcagca gtgttggtca cgatgatcat
      121 ggttgtatca tcaagacctg cttcagcaat cttagctgca tcaaatttag caagcggagt
      181 accagctttt actttatcac ctgctgctac taatttttca aatccattac cattcattga
      241 tacagtatca ataccgatgt gaattaaaag ttcagcacca gacgctgttt tcaatccgta
      301 agcatggcct gtttcaaaag caattgttac ttctgcatct gctggagcgt aaacaacacc
      361 ctcagatggt ttaacagcca aacctttacc catagctcct gatgagaaga ctgggtcatt
      421 aacattttca agggcaacaa catcacctga aagtggagat acaagagttt cttcgttgag
      481 ctcaacagct ggagttgcag gtgttgctac tggagctgcc gctgctttag gtgcagcttc
      541 tacttcatct tcaaaaccga agaggtaagt caatgcaaaa ccaagagcaa atgatacagc
      601 taccataagg atgtattgga acaattgacc attaccaaca taaagtgtcg caccaggaat
      661 gatggttaca cccatacctt taccagcaag accaagaaga gatgctacag caccaccgat
      721 ggcaccagca atcaatgaaa gaagaaatgg tttgcggaaa cgcaagttca caccgaagat
      781 agctggctca gtaataccga ggaaggcaga aagagctgct gggaaagcaa gagctttcaa
      841 tttaggattt ttagttttca caccaaccgc tactgtagca gcaccttgtg ctgtcatagc
      901 tgcagtgatg atagcgttga atgggttagc accagtgttt gctaccaatt gagcttccaa
      961 gaagttgaag atatggtgaa cacctgatac aacgataact tggtgaacac caccgataag
     1021 gagaccacca agccccattg gcaagttcaa gatagcttgt gtaccagcta agatgtagtt
     1081 ttcaaccacg tggaagactg gaccgatgac aaacaaacca agaatagaca tgacaaacaa
     1141 agtcacgaat ggtgttacta agaggtcaag aacttctgga acaaccttgc ggactgcttt
     1201 ttcaaattta gcaccaacca aaccgatgat gaaggctggc aatactgaac cttgcaaacc
     1261 aacaactggg atgaaaccga agaaaatggt tggcttcaca tcaccacctg aagcaacgac
     1321 ccaagcattt ggcaattgac cagcaatcag catcatacca agtacgatac cgatagtttg
     1381 gttcccaccg aatacgcgga aggttgacca taccaccaag gctggcaaga cgatgaaggc
     1441 tgtatcagtc aagatttgtg agtaaacgtt caaatcttct ggaagagtat agccgagagc
     1501 tccaagaaga ccacgaagac ccatgaaaag accagttgct acgatagcag gaatgattgg
     1561 aacgaataca tcaccgaaag tacggatagc acgttggaat gcattgcctt gtttagcagc
     1621 ttcagctttt tgttcaccag tagtcgctgt tggcaaacca agggcaacca cttcatcgta
     1681 gattttgttt actgtaccag taccaaagat gatttggtat tgaccagagt tgaagaaagc
     1741 accttgtact ttttcgatgt cttcgactgt atccttgtcg atttttcctt catcaacaac
     1801 cattacacgg aggcgagtcg cacagtgagc aacactgcgt acgttctcac gtccaccaag
     1861 ggcgtcaatg actttttttg caatttctgt attattcatc ttgcaaaaat ctccttatta
     1921 aatatttttt gttttttgaa agtgttttca aactttcgat ggttttatta tatcactttt
     1981 ataaaatatg tcaaacgttt atcacatttt gtttcaattt tatcaaaaaa cattgttaaa
     2041 acttgatttt tcgcaagaaa acgtttacta tattaatgaa aaactagaaa atttggagaa
     2101 aattatggca tttacaacag gggagcgtta cagagcttat gctgactgga cacccgaata
     2161 cattgaaaaa ataaagaaga atacagagag ttctccttgg aggacaaatt tccatattga
     2221 aacaccacat ggactgttaa atgatccaaa tggattttct tattttaatg gaaagtggac
     2281 tcttttttac caatacttcc cattcggtgc tgcgcacgga ttgaaatcgt gggtccatac
     2341 agaatcaaca gatttggtcc attttgaaga aactggtacg gttatgtacc cagatacacc
     2401 acttgatagc catggtgcct actctggatc tgccatggaa tttggcgaca agctcttcct
     2461 cttctacact ggaaatgtcc gcgatgaaaa ttgggttcgc catccatacc aaatcggtgc
     2521 cttgatggat aaagatggta agattgaaaa gattgataaa gtcttgattg agcaaccaga
     2581 agataccacc gaccatttcc gtgatccaca aattttcaac tataaagggc aatattacgc
     2641 tattgtcggt ggacaaaatc tggataaaaa gggaattgtc aaactttata aagctgaaaa
     2701 taacgactac ctcaactggt cctatgttgg tgaccttgat tttgccaatg atatgaccgc
     2761 ttatatgatg gaatgcccaa atattgcgtt cgtcggtgag caacccatcc ttctctattg
     2821 tccacaaggt ttggacaaag aggtattgga ctatggcaat atctatccaa atatgtacaa
     2881 gattggtcag agtttcgttc ctgaaacagc aagcattgtc gaaccgagcg aattgatcaa
     2941 tctggactat ggttttgagt gctatgcaac ccaggccttt aatgcaccag acggtcgaac
     3001 tctatctgtt agctggttgg cacttccaga tgtggaatac ccaaccgatg cttatgacta
     3061 ccaaggctgt ctgtcattgg ttaaagaatt aaccatcaag gacggtaagc tctaccaata
     3121 tccagtcgat gcgattacca gtcttcgtaa agaagctcag ccattttcag cccaaaaaga
     3181 aaccaataat gtttacgaat tggaacttga tttttcagcg agcacgaagc acgaaatcgt
     3241 attgttcgca aatgaagcag aaaaaggctt ggtcttgtct gtagacactg aacaaggcca
     3301 gattacattg gaccgtggca actgtggtca gccattcgca ctcgatttcg gcacaagtcg
     3361 ctcttgcgag atttctccag gagctcttac agccaatatc ttcatcgaca aatctgtctt
     3421 tgaaatcttt atcaataaag gagagaaagt attttctggt cgtgtcttcc ctgatgcgga
     3481 tcagtctggt atagtcatta cgactggtaa tccgaccgga acctactacc atttagatta
     3541 tggtcgcaaa actaactgat gtcgcacagt tagctggggt cagcccaaca actgtctcgc
     3601 gcgttatcaa taaaaaagga tacctatctg aaaaaaccat tcgcaatgtc gaagaggcta
     3661 tgcgtgaact aggctacaaa cctaataatt tagctcgtag tttgcaaggt aaatctgcaa
     3721 aattagttgg tctcatcttc ccaacaataa acaatatttt ttattctgaa ttgattagcc
     3781 atttagaaaa agagcttttt gatcgaggct ataaaaccat tatttgcaat agccagcacg
     3841 agtccgataa ggaacgtgag tatctagaaa tgttagcagc taaccaagta gatgggatta
     3901 tctcgggcag tcacaatctc ggtatccaag actacgaccg tgtcgtagct ccaattatcg
     3961 cttttgaccg caacctatct ccttccattc ccattgtctc ttccgataat tttgctggcg
     4021 gggtattagc tgcccaaacc ttacaaaaag cgggatgtca caatccatta atgattacgg
     4081 ggaacgatga ttccaattca cctaccggcc ttcgccaagt aggttttaca tctattttga
     4141 acaaagccga agtttttcat atctccagtg atttctcacc tgtgcgtaag gagatggaaa
     4201 tccgagccat tcttgaaaag caaaaaccaa atggtatctt tgtatctggc gatgcaacgg
     4261 ctatgctggt atggaacgtc attcgttcaa tgaaactgtc tattccagaa gatattaaat
     4321 tgattggtta tgatggaacc agtttcatcg aaaactacta ccctcaactg acaactatca
     4381 agcaaccatt aaccgaaata gctcgcctgc tggttgaact attagttgat aaaatcgaag
     4441 gaaaaaaact gacaaaaaca gactatatcc tgccgattag cctactagca ggagctagta
     4501 tataaaaaaa gctgtaccta ataaaaatta ggtgcagctt ttttgtgata cattctctta
     4561 tttctcaagt aaaaaagaag ctcatcaggc ttcttcttta ataaactggc tcaaaactcc
     4621 attgacaaac ttagctgaag attcatcaga aaattcttta gccaattcaa tagcctcgtt
     4681 aacagcaacg cggtctggcg tttcttcgaa atgtaagatt tcaaataggc ctagtcgcat
     4741 gatattcttg tcaatcaagg ttaaacggtc taaggtccat cctgctttta atcggctaga
     4801 taactcctta tccaagtcat cacgatagtc tgctacacca ttgacaaggt taaggagaaa
     4861 gagcggaatt tcaactcctt cttgctcttc ttctctatca taaagataag aaaactgagc
     4921 tgcctgaaca ggttcttgac caaattcaag tgatacgatt gcctgcaaag cacacttacg
     4981 cagggcatgt ctattattct tcatcaagga aatcctctcc gaataaatct ttcaatgctg
     5041 gttttggtgt tttatcagga acaatgccgc tgacatggat attaaccgca gccacttgaa
     5101 cttctgcata gttataaact gctgtcttga ctgcacgttg gatgtccatt gatacggcag
     5161 gaacatttac accatattct agatagacgt aaatatccgc agtcactcga ccttcctcgt
     5221 cagtttcaag ataaacacct ttatttaacg atgtttttga ccaactgtct gctacacgct
     5281 tattttgaag ggaatgcact ccatcaactt tcgctgcagc aatgcctgta attacttcaa
     5341 ggacgcgagg tgcgataaca atctcgcctt gatattctgt tgtcataggc tctcctttct
     5401 taagaggaaa cgattaagca cgtgatacgt aagttccttc agctgtgttg ataacgagtt
     5461 tttgacctgc ttcgataaag tctggtacgt tgactacaag acctgtttcc atcgtagctg
     5521 gtttacctga acctgtaaca gtcgcacctt tgatagatgg ttgtgtttct gcaacgacca
     5581 attcaacagt tgttggtaca gtaacaccga tcacttctgt tccgtagaac tggatcttca
     5641 cttcagaatt ctccaagatg tagagcaatt cttctttgat agtcgctact ggaatttcat
     5701 actgatcgta agtctcagta ttcataaaat aagctgtgtc atccatttgg taaaggtact
     5761 gtgctggaac tgtttcgata atagcttgtt caaatttttc atctggacgg taagttgtat
     5821 cgaaggttga acctgtacgt acatcacgca atttcatacg catgatggtg ttacctttac
     5881 ctggtttgtg gtggctcgca tccaaaactt taatcaattt accttcagct tcgaaggtca
     5941 tacctgctct aagtttactt gcttcaatca ttgtattgaa tacctcttca aattttattt
     6001 attcgtttta ttctaccaca aactgtcaaa tttctcaaat gacaatcaat tccttgggag
     6061 ctaatgtcaa gacttcacaa ccgttttccg taatcaatag gtcatcttcg atacggacac
     6121 catatttgtc atccaaatag ataccaggct catccgtcaa aaccataccg gccttgatag
     6181 tctcgtcaga ttttccaaaa tacggatatt catgaatatc caagccaata ccgtgaccga
     6241 tgccgtgtgt aaagttggct ccgtaacccg ccgcactgat aatctcacga ggaatagcgt
     6301 caaactcgcg gtaggtgaca ccttccttgg cctgctcaat caaagcctta ttggcacgca
     6361 agaccacatc gtaaatctca cgctcttgat ctgtcacatg accgatatgg atggtccgtg
     6421 tcatatcgct gacataatgc tggtaatagc aaccaaaatc cagcgtcaag gtctcaccag
     6481 attggataac cttttcagac gctcttccat gaggcatagc agagcggtag ccagatgcca
     6541 cgatgaactc aaatgatgcc ccttctgcac cgagttgacg catgcggtgg tcaaggaaat
     6601 gattgacgtc catctcagtc gtctgacctg gtttgataaa gtcaagaaca tcaataaaag
     6661 cctgatccga aatttgacat gcacggcgaa tggtcgcaat ttctttctca tccttaatca
     6721 tgcgcaagtc ttcgataaag tttgacatag caaccagttg ataaccctca aaaatgctgg
     6781 tcagactttg atagaaacca taggtcacct cgctatcaaa accaattttt tcaagcccat
     6841 cttccttaat cacctttgca atttcttcaa gggcaaaacg gctctcgata atatcaaaac
     6901 cttttactga tgccttggct atcaaggtat aacgcgaatc agtcacaaac aagcgacgct
     6961 tgccactaat gaagacagtc gcctctgtcc cccaaaaacc tgtcaggtag taaatattgt
     7021 tttgaccagt taccaagatt ccatcaacag ttgattgagc taattttgct tcaaattttt
     7081 caagtctttt ttgcatccta ttcctccaat gattttttaa ctattatagc agaaatacag
     7141 acaaatacca attcttccta gcagatagag aaaaaaagcc gcagaggcga ctttttattt
     7201 caacttcatt ttcagatact ggcctgtaaa gctggctggg ttctccgcca cttcttctgg
     7261 tgttcctgtc gcgacaacgg taccgccacc gacaccgcct tccggtccca tgtcgataat
     7321 gtggtcggct gtcttgataa catccagatt gtgctcgatg accagcacgg tattgccatc
     7381 atcaacaaag cgagccaaga ccttgagcaa ctgggcaatg tcctccgtat gcagacctgt
     7441 cgtcggctca tccaagatat acaaggattt accagttgac cgcttgtgga gttcagaagc
     7501 caacttcata cgctgggctt ccccacctga tagggtcgtt gctggctgac ctagagtaac
     7561 gtagcccaaa cctacatctt gaatagtacg aagtttccgc tcaatttttg gaatatgctt
     7621 gaagaactcg accgcgtcat tgaccgtcat atcaaggacc tgagcgatat ttttctcctt
     7681 gtagtgtact tccaaggttt cagaattata gcggtgtcca tgacagactt cacaaggtac
     7741 aaagacatcg ggcaggaagt gcatttcaat cttgataatc ccatcaccag aacaagcctc
     7801 acaccgtcca cctttgacgt taaaggagaa acggcccttc ttgtagccac gaatcttggc
     7861 ttcattggtc tgggcaaaca aatcccgaat atcgtcaaag acacctgtgt aggtagctgg
     7921 gttagaacgt ggtgtccgtc caatcgggct ttggtcaata tcaatcaggc ggtccaagtg
     7981 ttcaattcct gaaatagact tgaacttacc tggcttgtcc gaattgcgat tgagtttctg
     8041 agcaatagct tttttcagaa tggaattgac cagagttgac ttacctgagc cagacacccc
     8101 tgtcaccgct acaaattttc cgagtgggaa acgaacagtc acatcttgca ggttgttttc
     8161 cttggcaccg gtcacctcta agaatcgacc atttccaaca cgacgttcca aaggaactgg
     8221 aatttcacgt ttgccagaca ggtactggcc tgtaatggat ttcttgtttt tagctacttg
     8281 ggctggtgtg ccagaggcca cgatttctcc gccaaacaca cccgcacctg gaccgatgtc
     8341 aatcaaccag tccgcctcac gcatagtgtc ctcatcatgc tccaccacaa tcaatgtatt
     8401 gcccaaatca cgcattttct taagactagc aatcagacgg tcattgtccc gctggtgcag
     8461 accaatcgac ggctcatcca gaatatagag gacaccagac aggttagagc caatctgagt
     8521 cgccagacga atccgctggc tctcaccacc agaaagggta cctgctgctc gtgaaagagt
     8581 cagatagttg agaccaacgt tatttaggaa ggacaggcga tccttgattt ccttgacaat
     8641 gggtgttgca atggtggctt cattttcaga caaggtcaga tgttcaatga cttgcaaatg
     8701 atccgccacg gacaagtctg ataattgtcc gatatgaagt ccctgctcgc ctccgacttt
     8761 gacagacagg gcttggtcat tgaggcgata gccgtggcag gtcccacagg tcagttcatt
     8821 catgtaagtc ttcatgactg tccgtgtgta atcactattg gtttcacgat agcggcgatt
     8881 aatgttggta atcaagccct cgaatggaat gtcaatatct cggactccac cgaactcatt
     8941 ttcataatgg aaatggaatt ctttcccgtc agaaccgttg aaaatcaggt tcttctcctc
     9001 ttccgtcaat tcctcaaaag gcttgtccat gtccacacca aagtgattca tggcctgctc
     9061 caacatctga ggatagtagt tggatgagat tggattccaa ggagccaagg caccttcacg
     9121 caaggtcttg ctggcatctg ggacaatcaa atccgtatcc acttccagct tcatgcccaa
     9181 accgtcacag tcgctacaag acccaaaagg agcattgaaa gagaagaggc gaggctccaa
     9241 ctctggtacc gtaaaaccac aaactgggca ggcatagtac tcagagaaaa gcatttcctt
     9301 ctcatccatg gtgtcgatga tgacatagcc gtccgcaatc cgcagggccg cctcaatgga
     9361 gtcaaaaagc cgcgagcgaa tgccatcttt gatcacaatc cgatcgacca caacttcaat
     9421 attatgagcc ttgctcttgg acaattctgg tacttccgac acatcataga caccgccatt
     9481 gacacgtacc cgaacatagc cgtccttctg gattttctca aaaatggtct tgtgttgccc
     9541 ctttttctta cgaacaatcg gagctagaat ctgcaaacgt tggcgttctg gcaattccaa
     9601 gacctcatca acgatttgtt ccaccgaaga agccgcaatc gctccgtggc cattgataca
     9661 gtaaggtacc ccaacccgag cataaagcaa gcggagatag tcattgattt ccgtcgctgt
     9721 accgactgtc gaacgcggat tccgcgatgt ggttttttgg tcaatggaaa tagcagggct
     9781 gagaccctct atggaatcca catcaggctt gtccatgttg cccaagaact gacgagcata
     9841 ggcagacaaa gactccacat agcgacgttg accctcggca tacaaggtat cgaaagccaa
     9901 actcgactta ccagaccccg acaaaccagt caccaccacc agcttctcac gcggaatggt
     9961 cacatcaata tttttcaaat tatgggcacg cgccccatga atcacaatat tttcttgcat
    10021 aacatgatat aagtgcgtta agaaagcgat aagaaaatag gaaaatgtga cgtcacatca
    10081 gtgacaaaac attttgtctt tttctcgacg cttttagcac gcattcgaat cctttctaag
    10141 atataaagag catcaaatgc acagtcaaaa taggcggtaa gtccgaattc tgtgatttcg
    10201 aagatgcacc cccttcaaga caactagtgc tttcacaggt tgaaaaccga agaaagtaca
    10261 gatgtctacg acgcagaaac cagttcccat acttatccat gaagaaacta gcactttttg
    10321 acaccgcatt tagcccgtgt tcaattcctt tcttaagagg ctataagcta tggtatacgg
    10381 aacaaggaaa agtccgtaca acttattcgc ttaaatgtct acatattata tcacatttct
    10441 atataaaacc tttccgaaac tgcacatttt ttggtataat agaggttgcg ttaacgcaac
    10501 aaagataaaa ggagggcaaa gatatgaaac aaatttttct atcaaccatg actgatttag
    10561 aagaaatcca aacctttgaa ccaggggctt ggattaattt ggtcaacccc tcccagagcg
    10621 agtctatgga agtggctgag cactataaaa ttgacatcgc tgacctgcga gcaccgctcg
    10681 atgcggaaga atcctctcgt atcaccgtcg aagatgacta tacgctcatc ctggtcgacg
    10741 tcccaattct tgaagaacgg aacaacaaga catattatat tactattcct ttgggaatta
    10801 ttctaacaga tgatgcaatt atcacgactt gtttggaacc attgccactg tttgagcagt
    10861 ttatccatcg tcgtctacgg aatttcttca ctttcatgaa gtctcgtttc gttttccaaa
    10921 ttctctaccg aaatgctcaa ctctacttgt cagccctacg gaccattgac agaaagagcg
    10981 aagagattga gaagcaactc catgaagcca ctcgaaatga agaattaatt gtactcatgg
    11041 aattagaaaa aaccatcgtc tacttcaagg cttccctcaa aaccaatgag cgtttggtca
    11101 aaaaacttgc tagttcctca cgcctactcc gtaagtatga agaggatgag gatttgcttg
    11161 aagatacctt ggtcgaaacc caacaggcca ttgagatggc agacatctat ggttccatcc
    11221 tgaactctat gacccatgcc tttgcttcta tcatttctaa caaccagaat accatcatga
    11281 aaaccttggc attagtgaca atcgttctct ctatcccaac catggtcttc tctgcatacg
    11341 gtatgaactt taaggacaac atcattcctt ttaacgatat tccctatgct ttttggtgga
    11401 ttatcctctt cgcatttgca atcagcctat cactcacctt ctacttcatc cgtaagagat
    11461 ggttttaaac taaggagatt aacatgtcat ttacagaaat caacggatta acaaaaaaga
    11521 accaagaatt tatccatatt gcgaccaacc aactgattaa agatggaaag tctgatagcg
    11581 aaatcaaaga actcttggaa gaaattttac caactatcat tgaaaagcaa aaaactggtg
    11641 tgactgcccg caatctctat ggagcaccaa gtgagtgggc tgctagtaag acaatttctg
    11701 aacaggaaaa gaaagaccaa gtggaataca atgaaaatcc atggttgatg tggctagatt
    11761 ctagtctttt catgcttgca attattgctg gtatcaatgg tttgatgaat ctttttggtc
    11821 aaggtgcaca gtatgggcta ttaaccttat ttgtcatcgg tttcggtgtt ggtgcaggga
    11881 tgtacttgat gtaccatttc gtttacagag aacaaattaa aactgggcaa cgtcctaaat
    11941 tgctgaaagc tatcgctttt ctcggacttg ctacgctggc ttggtcagtc gttttcattc
    12001 tggcagcact gattccggcc gcatttaacc cggttcttcc tccgcttgtt actattctta
    12061 tcggagctgc tgctttcggt gcacgctacc tcttgaaaaa gaaatataac attcgcaatg
    12121 ccatgtcccc agttcaataa taaaacaaag cgattggaat attccagtcg cttttgttta
    12181 tctatacagt tcagctatca aatcgcccga gaaccttatc cgctgtcact tgtctatgta
    12241 atctgctgaa acagtctatc cccagactgt gcctcgcttt ctaacttctt ggctcgggtt
    12301 gaaacagtcc attcaaaggc ttaattcgct ttcttaattt cgagttcatg aaaaaatggt
    12361 ccactctcgc cgttgcgcct ttccagtttc ttgggcgcaa gctaaaaaga cccgtcgggg
    12421 tctcaattcg ctttcttatt ttcatgctca tgaaaaaaca gtccattctc gccgttgcgc
    12481 ctttccagtt tcttgggcgc aagaaaaaat ggtccactgg accatttttt taatcttcgt
    12541 ttacgaatgg taaaagagcc ataacgcgag cacgtttgat agctgttgtt actttacgtt
    12601 ggtttttagc tgaagttcca gttacacggc gtggaaggat ttttccacgt tcagaaatga
    12661 aacggctaag aagctcagta tctttgtaat caacatattc aattttgtta gctgcgatat
    12721 agtcaacttt tttacggcgt ttgaaaccgc cacgacgttg ttgagccatg tgtgttctcc
    12781 tttatattat taatttttga cctagaatgg taggtcatcg tctgatatat ccattggatt
    12841 acttgctcca aatggacttt cttctcgagc gaagtttggt gtagattgtg caggcgcttg
    12901 ataaggcgag ttatagtcat ttcctccagc aaacgagttg ccagctgaat agcctccacc
    12961 ttgaccttca cgggcagtac ggctttccaa gagttggaaa ctttctgcaa ctacctcagt
    13021 aacgtagaca cgttgccctt gctgattgtc atagctacga gtctgaatac gacctgtaac
    13081 accaatcaga gcacctttct tagcccaatt cgccaaattc tcagcttgtt gacgccaaat
    13141 gactacgttg ataaagtccg cttcacgctc accgttttga tttttaaaat tgcggttaac
    13201 cgccaaagta aaagtcgcaa cagcttgatt agacggagta taacgaagtt ctgcatcacg
    13261 ggtcatacga ccaaccaata ctacattatt aatcatacaa caccttctta cgcgtcaagt
    13321 ttgacaatca tgtgacgaag aatgtcgccg ttgatttttg acaaacggtc aaactcttta
    13381 agagcttcat cgttgttagc ttcaacgtta acgatgtggt acaaaccttc gcggaaatct
    13441 ttgatttcgt atgcaaggcg acgtttttcc catgcttttg attcaacgat agttgcaccg
    13501 ttgtcagtca agatagagtc aaagcgtgct accaaagcgt ttttagcttc ttcttcaatg
    13561 tttggacgaa taatataaag aatttcgtat ttagccattg atatgttcct ccttttggtc
    13621 taatgactca tggtctagcc acgagtaagt gagggatact cacagaaaat aattatacca
    13681 taatatagaa aatgtgcaag tgaaaacaat tttccgaaaa cattttcaca aa
//
LOCUS       DBNFCO010000053        13194 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.053, whole genome shotgun sequence.
ACCESSION   DBNFCO010000053 DBNFCO010000000
VERSION     DBNFCO010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 13194)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13194)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13194
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.053"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(196..534)
                     /locus_tag="AC1PIV_001387"
     CDS             complement(196..534)
                     /locus_tag="AC1PIV_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HIP6612406.1"
                     /translation="MSTNIYDIANELERAIRNLPEYKAVEAVKVSVEGNSEAKEILES
                     YISFQKEIQSKLQAGEIPTEADQKKMLDFNKKVQGNPLLTEYFSKQQQLGTYVADLER
                     IIFKPLNELL"
     gene            complement(544..1647)
                     /locus_tag="AC1PIV_001388"
     CDS             complement(544..1647)
                     /locus_tag="AC1PIV_001388"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HIP6612407.1"
                     /translation="MKKTILIVGLGLIGSSLALCIRKDHPDYHLIGFDPNEQSCQIAL
                     GKGMVDEVSTELEGVAKQADVILLCVPIQVSLRLIEEFSALELKDTVLITDAGSTKSA
                     IVAAAEEHLAPRQINFIGGHPMAGSHKSGASAADLHLFENAYYIMTPCQATKQDAVPR
                     LTDLLSGTGARFVQIDAAEHDRVTSQISHFPHVLASSLMHQAGEYAQDHPFTNNFAAG
                     GFRDMTRIAESEPSMWTSILLTNADSILNRIEEFQARLSEISDVLRSGDQKAIWDFFD
                     KGRQTRKAMEIHKRAGVDSFYDLFLSVPDEEDTILKVLEVLRGISIVNIRINEENRED
                     IHGILQITLKNKGNLEDAAKRLREQTTYKIHLD"
     gene            complement(1655..2821)
                     /gene="aroC"
                     /locus_tag="AC1PIV_001389"
     CDS             complement(1655..2821)
                     /gene="aroC"
                     /locus_tag="AC1PIV_001389"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002997861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HIP6612408.1"
                     /translation="MRYLTAGESHGPRLTAIIEGVPAGLPLTAEDINEELKRRQGGYG
                     RGSRMQIETDRVEITAGVRHGKTTGAPITLNVTNKDHQKWLDIMAVEDIEEKLKSKRR
                     IKHPRPGHADLVGGMKYRFDDLRNSLERSSARETTMRVAVGAVAKRILAELDIEIANH
                     VVVFGGKEIDVPDGLSVAEIKERAAQSEVSIVNQEREEEIKAYIDQIKRDGDTIGGVI
                     ETVVGGVPAGLGSYVQWDKKLDAKLAQAVVSINAFKGVEFGVGFQAGYLKGSQVMDEI
                     LWSQEKGYTRRTNNLGGFEGGMTNGEALIIRGVMKPIPTLYKPLMSVDIDTHEPYKAT
                     VERSDPTALPAAGVVMESVVATTLATEILEKFSSDNMEELKAAVASHRDYVKNF"
     gene            complement(2825..3499)
                     /gene="aroD"
                     /locus_tag="AC1PIV_001390"
     CDS             complement(2825..3499)
                     /gene="aroD"
                     /locus_tag="AC1PIV_001390"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HIP6612409.1"
                     /translation="MKIVVPIMPRNLEEVEAIDVERLAEADIVEWRADYLLKDDILRV
                     APAIFEKCSGKEVVFTIRTTREGGHLDLDDQEYVNVIKEVATLYQPDYIDFEYYSYKS
                     VFEQMLEFPNLVLSYHNFEETPSNYMEIMSELTSLSPAVVKMAVMAKTEQDVLDVMNY
                     TRGFKSLNTEQIFATIAMGELGKLTRIAGVITGSCWTFASLDETSAPGQMSLSNTRKF
                     LEILEN"
     gene            complement(3496..4659)
                     /locus_tag="AC1PIV_001391"
     CDS             complement(3496..4659)
                     /locus_tag="AC1PIV_001391"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HIP6612410.1"
                     /translation="MKIKVNRIAEQKINRGIQLLDSADFSGVSFDEDRLAVLYSESGS
                     YLGQAYLSKQNKGIGWLFSRSNQDLTMDFFVKLFVDAKQKRQHFYQSEMTNAFRLFNQ
                     DGDSFGGMTVDLYDEYAVFSWYNTFIYSVKEMIVAAFQQVFPEVRGAYEKIRFKGLAF
                     ESAHLYGEEAPEYFTVLENGVHYQVFMNDGLMTGIFLDQHEVRGSLVDGLAAGKSLLN
                     MFSYTAAFSIAAAMGGAEETTSVDLAKRSRELSKAHFKVNSLDLDNHHFVVMDVFEYF
                     KYAKRKGLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNTGGTIIASTNAA
                     NVSVEKFKRQIEKGFDVRKHRYEATYRLPADFVINKNDESSNYLKVFTIQVDK"
     gene            4775..6955
                     /locus_tag="AC1PIV_001392"
     CDS             4775..6955
                     /locus_tag="AC1PIV_001392"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070395 - lipoteichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HIP6612411.1"
                     /translation="MKKLIDYVKKSGQTRLGFVLILLIIYWLKTLWAYYVDFNLDTQG
                     FFQNFIAIMNPLPVGILLLGLSLYIKNTKVFYSVAMIIYIILSVWLFSNAVYYREFSD
                     YISISTIMATSSVSAGLGEAALKLFRLWDIVYFLDFIIFGILVYRKLLRWDKKTFHKK
                     SSFAITALSVMLFSINLFLAEIDRPELLTRGFSNTYIVRALGLPAFLGYNANQTYNAH
                     KNRSGASATDLEPVKQYITEHYAQPNDNYFGIAKGRNVIYLHLESLQQFVIDYKLNVN
                     GVEHEVTPFLNSLYHSSSTLAFSNFFNQVKAGKTSDAETMIETSLFGLNQGSFMVQYG
                     GSNTQQAAPYILSQNGGYTSAVFHGNAASFWNRNNTYKQWGYNYFFDQSYFSKATAEN
                     SFQYGLNDKIMFADSIQYLEHLQQPFYTKFITVSNHYPYTTSLIGDEIGFPLANTDDE
                     TINGYFATANYLDASIKAFFDYLKATGLYENSIIVLYGDHYGISNSRNPDLAPLIGKD
                     SQTWSDFDNAMMQRVPYMIVVPGMTNGGIFDTYGGEIDALPTLEHLLGIKSDNYLQVG
                     QDLLSSQHSQIVALRTAGSFITPKYTSYEGKIYYTETGLEITNPDETTQKEIDAIKEA
                     TAAQLATSDAIQTGDLIRFFDNGLPALDPSQYNYIDSLAAEIALENKLGKQSTSLYST
                     NGNKSTIELFKAPSYLELHGSTTATSTPNTGTSTSSTSTSSNSR"
     gene            complement(7151..9655)
                     /locus_tag="AC1PIV_001393"
     CDS             complement(7151..9655)
                     /locus_tag="AC1PIV_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HIP6612412.1"
                     /translation="MKQGKTLLYVAGASLICAVALVTYQASNYREQSNHQKTTSIETS
                     QSKQSKEIPSDSKKEVPGIDKATDDVFLLTDESQIEEKTDLGIIVNHGDHKHFFFYSD
                     LKNTKWAYLIPENYQEKNHSSQPKRSQLSSGSKQIEDEYVFDPKDIVAEDANGYTVRH
                     GDHYHYILKSSLGGTTHRQLTSDSRQSPTLPIVHQQEGIPGIDFQTSDGFLFDGQNIS
                     GVTETGILVRHGKHLHLIHFETLKRSKWSYLVNQYKPNVESDKKAQPEVENTEYQTKL
                     DYLAKELNLEPSRFKKVIVDGQIGLEYPHGDHTHIVLLKEIDTTKPFESPEDRILKQK
                     DGETLEQRKERLIKQYMERFKVKREDITIDGNYMSVRHGDHAHVYKIDPSLPDDPERD
                     VKTETVNLAIEKQLVYGPFYTEGSTENLTRNGVHQKYRPEGLQDIKNFILVTFSTNSD
                     FGNFVVNGKKTKRVYYLVRKDLNWEDLNIAYPQTLQQKGRVFNGWNATLPKSGKMARE
                     HQSFYADFDNVYRKPTKNIYTPSDDVSNIDLSDYVPVKYSAIANGRLKLNGEIRAGFI
                     YFVKSDLTWKQAKEQGLVVPEPVSSKDYEFIEFRTVITGGEKDTDYVSATTSLAAFGT
                     TAPRIGPYIANNTENPTDINDPSRHPNYYWHDPKNYVALAFRAGEGGQLQTHLGTSKT
                     VVYLVRKGLTLNQAGIFPPSLKSDTGYKRDYTKPVIPNVAWDTPILEDTVYDIHFDKV
                     ESDSKDGTVEPGDTWLPGNPLANTPDVPNGEEDADSWLDDLLTPSPEATDIETVTEAE
                     TTTEDTKATESSTAAPIDIPKKSSTEEEPSEDFIFP"
     gene            complement(9981..10340)
                     /gene="rplT"
                     /locus_tag="AC1PIV_001394"
     CDS             complement(9981..10340)
                     /gene="rplT"
                     /locus_tag="AC1PIV_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HIP6612413.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHLLFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AAAFTALADAAKAKLAK"
     gene            complement(10384..10584)
                     /gene="rpmI"
                     /locus_tag="AC1PIV_001395"
     CDS             complement(10384..10584)
                     /gene="rpmI"
                     /locus_tag="AC1PIV_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HIP6612414.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKAGMVHAGDFKRIKSMLTGLK"
     gene            complement(10611..11117)
                     /gene="infC"
                     /locus_tag="AC1PIV_001396"
     CDS             complement(10611..11117)
                     /gene="infC"
                     /locus_tag="AC1PIV_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HIP6612415.1"
                     /translation="MFINDEIRVREVRLIGLEGEQLGIKPLNEAQAIADSANVDLVLI
                     QPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPVIDKGDFETKLRHA
                     RKFLEKGNKVKVSIRFKGRMITHKEVGAKVLAEFAEATQDIAIIEQRAKMDGRQMFMQ
                     LAPASDKK"
     misc_feature    complement(11158..11286)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            complement(11313..11990)
                     /gene="cmk"
                     /locus_tag="AC1PIV_001397"
     CDS             complement(11313..11990)
                     /gene="cmk"
                     /locus_tag="AC1PIV_001397"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004127 - (d)CMP kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HIP6612416.1"
                     /translation="MKSIQIAIDGPASSGKSTVAKIIAKNLGYTYLDTGAMYRSATYL
                     ALTNGIEVTDQNRIVDLLAQYPIRFGRDENGQQLVFVGDEDVTLPIRDNQVTNNVSAV
                     AALPLVREELVRLQQDIAQAGGIVMDGRDIGTVVLPQAELKIFLVASVEERALRRFKE
                     NTERGIETDLESLKEEIAARDYKDSNREVSPLKAADDAITFDTTGVSIEGVVKFISEK
                     AKEILDR"
     gene            complement(12000..12476)
                     /locus_tag="AC1PIV_001398"
     CDS             complement(12000..12476)
                     /locus_tag="AC1PIV_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1386/EF1546 family surface-associated
                     protein"
                     /protein_id="HIP6612417.1"
                     /translation="MSQEPWNEEVYHTETTSRKERLSKGVANTTVFTVLAIIFFVIVL
                     IIGIMAVYLSIGGGSKTDSTKEFYTPSTTTVVAESSSSAAETQESTSTDTTETETSSS
                     PAEATDGSTLTVQAGEGVGQLAARGGISIAELERLNPEKMTTGSWIAHPGDVVRIR"
     gene            12527..12721
                     /locus_tag="AC1PIV_001399"
     CDS             12527..12721
                     /locus_tag="AC1PIV_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009910133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HIP6612418.1"
                     /translation="MKVKLIPERCIACGLCQTYSSLFDYDDDGIVVFSDDSQFEKTIE
                     PNPDILKAIKSCPTKAISAD"
     gene            complement(12710..>13194)
                     /locus_tag="AC1PIV_001400"
     CDS             complement(12710..>13194)
                     /locus_tag="AC1PIV_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HIP6612419.1"
                     /translation="KIFGKIRYHWQPDLSWAIIYWSLTFTPIFIGMALLLEKLQVSRL
                     FILLVSLFAVLVVLGLHRYFEIKDEHLRIASANPFAVQKIEIATIEKIEVSYLAIRIF
                     AKEFPNGRMYYMRKWTKKYFINHLAIHSCFKGKIELIDHLIKQDYFEEYYTKKAKSIR
                     "
BASE COUNT         3869 a         2914 c         2250 g         4161 t
ORIGIN      
        1 acttctatta gaaaatgtca agtaattacc ataactttat aagaaatgga tgctgtgaga
       61 aggtagaaaa aagagttctt actgccctaa gtaccgtttc tgaatctgta cttggagata
      121 agaactctac gtaagcagtg tatactaggc gtcaatccat gacctaacac cctgctccta
      181 tcaaatataa atatattaca acaattcgtt gagaggcttg aagatgatac gttccaaatc
      241 agctacataa gttcccaact gttgttgctt gctgaaatat tccgtcaaaa gtggatttcc
      301 ctgaactttc ttgttgaaat ccaacatttt cttttggtca gcttcagtag gaatttcacc
      361 agcctgcaat ttagattgga tctctttttg gaaagaaata taactttcca atatttcttt
      421 ggcttctgaa ttcccctcaa ctgagacctt aacggcttcc accgccttat attcaggcag
      481 gttacggatt gcacgttcca attcatttgc gatatcatag atatttgttg acatattttt
      541 ctcctaatct aaatggattt tgtaagtcgt ctgctctctt aaacgtttcg cagcgtcttc
      601 caaatttccc ttgtttttaa gcgtgatttg taaaataccg tgtatatctt cacggttctc
      661 ttcattgata cgaatattga caatggaaat accccgtaag acttccaaaa ccttcaaaat
      721 cgtatcttcc tcatcaggaa cactaaggaa taaatcgtag aaagaatcaa cacctgcacg
      781 cttgtgaatt tccatggctt tacgagtttg acgtccctta tcaaaaaagt cccaaattgc
      841 tttttgatcg ccagatctga gaacatctga aatttctgaa agacgtgctt gaaattcctc
      901 gattcgattt agaatagaat ctgcattggt tagcaaaatg ctagtccaca tgctcggctc
      961 actttccgca atccgtgtca tatctctaaa tcctccagct gcaaaattat tcgtaaaggg
     1021 atgatcttga gcatactcac cagcttgatg catcaaacta gaagccaata cgtgtggaaa
     1081 atgtgaaatt tgactggtca cacggtcatg ttctgctgca tcaatctgaa caaaacgtgc
     1141 ccccgttcca gataacaagt ctgtcaatcg gggaaccgca tcctgcttgg tagcctgaca
     1201 cggtgtcata atgtagtaag cattctcaaa tagatggaga tctgctgcac tggcaccaga
     1261 tttatgacta cctgccatag ggtgtccacc gataaaatta atttgtcttg gcgccaaatg
     1321 ttcctcagca gcagccacaa ttgcagactt cgttgaacct gcatctgtaa tcaagaccgt
     1381 atccttcaat tcaagggcac taaattcttc aatcaaacgc aaagaaactt gaattggaac
     1441 acaaagaaga atcacatcag cctgctttgc tacaccctcc aattccgttg atacctcatc
     1501 aaccatcccc ttgcccaagg caatttggca tgattgttcg ttaggatcaa agccaatgag
     1561 gtgatagtct ggatggtctt tgcgaataca gagcgcaagt gaacttccaa tcaaccctag
     1621 acctacaatt aaaatcgttt ttttcattaa ttacctagaa atttttgaca tagtcgcgat
     1681 gactggctac cgcagctttc aattcctcca tattatcgga agagaacttc tctaggattt
     1741 ctgtcgctag agttgtagct acgactgatt ccatgactac accagctgct gggagagccg
     1801 ttggatctga acgttccaca gtagctttat aaggctcatg agtatcaatg tcaaccgaca
     1861 tcaatggctt atagagggtc ggaattggtt tcataacacc acgaatgatt agggcctcgc
     1921 cattggtcat accaccttca aaaccaccta gattattggt tcggcgtgta tatccttttt
     1981 cttgggacca gagaatttcg tccatgactt ggctcccttt gagataacca gcttggaagc
     2041 ctactccaaa ttctactccc ttaaaagcat tgattgaaac aacagcctgc gctaattttg
     2101 catctaactt tttatcccat tgcacataag accccaagcc agctggaact cctccaacaa
     2161 cagtctcaat cactccgcca atagtatctc catctcgctt gatttgatca atataggctt
     2221 tgatttcttc ttcacgctct tggttgacaa tggatacttc tgactgggct gcacgctctt
     2281 tgatttctgc tacgcttaaa ccatctggga catcaatttc cttccctccg aaaacgacta
     2341 catggttagc aatttcaata tccaactcag ccaaaatccg tttggcaacc gcaccaacag
     2401 ccacacgcat agttgtctca cgcgcactag aacgctccaa ggaattacgc aaatcatcaa
     2461 agcgatattt cataccacca actaggtcag catgtcctgg tcgtggatgt ttgatacgac
     2521 gcttactttt gagtttctct tcgatgtcct caactgccat aatatccaac catttttgat
     2581 ggtctttgtt ggtcacattc aatgtaatcg gggcaccggt tgtcttaccg tgacgaacac
     2641 cagctgtaat ctctacgcga tctgtttcaa tctgcatacg actaccacga ccgtatccac
     2701 cttggcgccg ttttaactct tcattaatat cctcggcagt taaaggaaga cccgctggaa
     2761 ctccctcaat aatggctgtt agacgtggtc catgagactc accagctgtt aaataacgca
     2821 taacttaatt ctccaaaatt tccagaaact tacgagtatt gcttaaagac atttgtcctg
     2881 gtgcagatgt ttcatctaag ctggcaaaag tccagcagga gcctgtaatc acacctgcaa
     2941 tacgtgttaa cttccctagt tcacccatgg cgattgtcgc aaatatctgc tcagtgttca
     3001 gtgatttaaa accacgagta taattcataa catctaggac atcctgctct gtcttagcca
     3061 ttacagccat tttaacaaca gctggtgata ggctagtcag ttcagacatg atttccatat
     3121 aattagacgg tgtttcttca aaattatgat aactcaacac aagattagga aactccaaca
     3181 tctgctcaaa aaccgactta taagagtagt attcaaaatc aatataatct ggctgataaa
     3241 gcgttgctac ttctttgatt acattgacat attcttgatc gtccaaatcc aagtgaccgc
     3301 cttcacgtgt tgtccgaatg gtgaaaacta cttccttacc actacatttt tcaaatatag
     3361 caggtgctac tcttaaaata tcatctttca gaagatagtc tgctcgccat tcaacaatat
     3421 ctgcctctgc taaacgttct acatcaatgg cctctacctc ttccagattt ctaggcataa
     3481 taggaactac tattttcatt tatctacctg tatcgtaaag acctttaggt aattactact
     3541 ttcatcattt ttattgatta caaaatcggc tggcaagcga taagttgcct catagcgatg
     3601 ttttctaaca tcaaaccctt tttcaatctg ccgcttaaat ttttcaacag aaacatttgc
     3661 ggcgttggtc gaagcgataa tagttccacc tgtatttagt atttccaaag attgagaaat
     3721 caacttgtga taatctttgg ctactgaaaa ggtttgtttc ttatttcgtg caaagcttgg
     3781 cggatccaag acaatcacat cataagttaa gcctttacgt ttggcatatt tgaaatattc
     3841 aaatacatcc attactacaa agtggtgatt atctaagtct aaactattaa ccttaaagtg
     3901 agctttagaa agttctcgcg agcgtttggc taagtcaaca gaagtcgttt cctctgctcc
     3961 gcccatggca gcagcaatag aaaatgctgc cgtatacgag aacatgttca aaagtgactt
     4021 gcctgccgcc aggccatcca ccaaggaacc acgtacctca tgctgatcca aaaagattcc
     4081 cgtcatcagt ccatcattca taaagacctg atagtgaact ccattttcca acacagtgaa
     4141 atactcaggg gcttcttctc cataaagatg agcagactca aaggccaaac ctttaaaacg
     4201 aatcttctca taagctcctc ttacttctgg aaatacctgt tgaaatgcag caacaatcat
     4261 ctctttgaca gaataaataa aggtattata ccatgaaaaa actgcgtatt catcatacaa
     4321 gtcaaccgtc attccaccaa aactatctcc atcttgatta aataaacgaa aagcgttcgt
     4381 catctcagat tgataaaaat gttgacgttt ctgtttagca tccacgaata atttaacaaa
     4441 aaaatccatg gtcaagtctt gattgcttct actaaacagc cagcctatcc ccttattctg
     4501 tttggacaaa taagcctgac ccaaatagct tccagactct gaatacaaaa cagccagcct
     4561 gtcttcatca aatgaaacac ctgaaaaatc agcgctatcc aagagttgaa tccctctgtt
     4621 tattttctgt tctgcaatac ggtttacctt tattttcata gaattattat aacatgtttc
     4681 ttcatatatg ccaaaaaaac tctaaacttt gaggcttatt ttagaattat ggtataatga
     4741 actaaacttt tagaaaggac catgaggttt tattgtgaaa aaactaattg actatgtcaa
     4801 gaagagcgga cagactagac ttggtttcgt cttgattttg ctaatcattt actggctcaa
     4861 aacactctgg gcctactatg ttgatttcaa cttagataca caagggtttt tccaaaattt
     4921 tattgctatt atgaatcctc taccagtcgg gattttatta ctcggtctct cgctttatat
     4981 aaagaataca aaagtcttct atagcgtagc gatgatcatt tatattattc tttccgtctg
     5041 gctcttttca aatgcagtct attacagaga attttccgat tatatttcca tctctactat
     5101 aatggctacc tctagtgtat ctgctggatt aggagaagca gctcttaagt tatttaggct
     5161 atgggatatt gtctattttc ttgattttat catttttgga atcctagtct atcgtaaact
     5221 actccggtgg gataaaaaaa catttcataa aaaatctagc tttgctatta cagcactatc
     5281 agtcatgctt ttctccatca acctcttttt agcagaaatt gatagaccag agctacttac
     5341 gagaggattt tctaatactt atatcgtcag agcccttggt ttacctgctt tccttggtta
     5401 caatgctaat caaacctaca atgcccacaa gaatcgttct ggagcatcag ctacagattt
     5461 ggagcctgtg aaacaatata ttacagaaca ttatgctcaa ccgaatgaca actacttcgg
     5521 tattgccaaa gggcgaaatg ttatctatct ccacctagaa agcttacaac aatttgttat
     5581 tgactataag ttgaatgtca acggtgtcga gcacgaagtc acacctttcc tcaattctct
     5641 gtatcattct agctctactc ttgccttttc caatttcttt aaccaagtta aggcaggtaa
     5701 gacctctgat gccgaaacca tgattgaaac ctctcttttt ggactcaatc aaggctcttt
     5761 catggtccaa tatggcggaa gcaataccca acaagctgca ccatatattc tctctcaaaa
     5821 tggaggatat acatctgctg tattccacgg taatgcagcc agtttctgga ataggaacaa
     5881 cacctataaa caatggggtt acaattactt ctttgatcaa tcctatttct ctaaagccac
     5941 tgctgaaaat tcattccaat acggtctgaa tgataaaatc atgttcgccg actctatcca
     6001 atatctggaa catttacagc aacccttcta taccaaattt atcacagttt ccaaccacta
     6061 cccctataca accagcttga ttggggatga gattggcttt ccattagcca atacagatga
     6121 tgaaaccatt aatggctatt ttgctactgc caactatctc gatgcgtcca taaaggcatt
     6181 tttcgattac ttaaaagcga ctggcttgta cgaaaactcc atcatcgtcc tctatggtga
     6241 tcactatgga atttctaatt cacgtaatcc tgacttggca ccgttgattg gaaaagattc
     6301 tcagacttgg tcagattttg acaatgccat gatgcaacgt gttccatata tgattgttgt
     6361 acctggaatg accaacggtg ggatttttga tacctatggt ggtgagattg atgcacttcc
     6421 cactctcgaa catcttttag gaatcaaatc cgataactat cttcaagttg gtcaagacct
     6481 actttccagc caacacagcc aaattgtggc tcttcgaact gctggcagtt ttatcacacc
     6541 aaaatacact agctacgaag gtaaaatcta ttatacagaa actggtcttg aaattacaaa
     6601 tccagatgag acaactcaga aagaaattga tgcaattaaa gaagctactg cagcacaact
     6661 ggcgactagc gatgccattc aaactggtga tcttatccgg ttcttcgaca atggattgcc
     6721 agccttggat ccaagccaat ataactacat tgactcattg gctgccgaga ttgcactaga
     6781 gaataaactt ggcaaacaat caacaagttt gtatagcaca aacggcaata aatcaacaat
     6841 tgaactattt aaagcaccaa gctacctaga acttcacggt agtacaactg ctaccagtac
     6901 accaaatact ggtacaagca ctagctcaac aagtaccagt tcaaattcac ggtaatacac
     6961 tataaaaggc ttagaatcat gtcagttact acattgattc taagcctttt tatactcaat
     7021 gaaaatcaaa aacagactag gcgacgcaga tgcagataga actgaagttc atcaaatcaa
     7081 gtcaacaacg tctgattttg attttcgaag agtattagac cactatttca aatcactcat
     7141 atctatttca tcaaggaaat ataaaatcct cactaggctc ttcctctgtt gatgattttt
     7201 tagggatatc tatgggagca gcagtactac tttcagttgc ttttgtatct tctgttgtag
     7261 tttcagcttc tgttacagtt tctatatctg tcgcttctgg actaggtgtc aacaaatcat
     7321 ctaaccagct atctgcgtcc tcttctccat tagggacatc tggagtattc gccaatggat
     7381 tcccaggcaa ccaagtatca cctggctcaa ctgtcccatc tttgctatca ctttcaactt
     7441 tatcgaaatg aatatcgtag acagtatctt ccaaaatagg tgtatcccat gctacatttg
     7501 gaataacagg ttttgtataa tctcgtttat aacctgtatc actcttcaaa gatggcggaa
     7561 aaattccagc ttggttcagt gttaaccctt ttctaacaag gtaaacaact gttttactag
     7621 ttcccaaatg tgtctgaagt tgaccacctt cacctgctcg aaatgcgagg gctacataat
     7681 tctttggatc atgccaatag taatttggat gtctacttgg gtcattgatg tccgttggat
     7741 tctccgtatt gttagcaatg taaggtccta tacgaggagc cgttgtccca aatgctgcca
     7801 agctcgttgt ggcactaaca taatctgtat ctttttctcc accagtaata actgtcctaa
     7861 actcaatgaa ctcataatct ttgcttgaaa ccggttctgg tacaacaagt ccttgctcct
     7921 tagcttgttt ccaagttaag tcagatttca caaagtatat gaaccctgct cgaatctcac
     7981 catttaattt taaacgacca ttggctatcg cactatattt aacaggtaca tagtctgata
     8041 aatcaatatt tgaaacatca tcacttggag tgtaaatatt tttggttggc ttacgataaa
     8101 cattatcaaa atcagcataa aaactttgat gttctcttgc catcttgcca gactttggca
     8161 aagtagcatt ccaaccgtta aagacgcgtc ccttttgttg aagggtctgc ggataggcga
     8221 tgttcaaatc ctcccaattt aaatctttac gaaccaaata ataaactctc ttcgtttttt
     8281 taccattaac gacaaaatta ccaaaatcac tatttgtact gaatgttact agaatgaaat
     8341 ttttaatatc ctgaagacct tctggacgat acttttgatg gacaccatta cgtgttaaat
     8401 tttctgttga accttctgta taaaaaggtc catatactaa ttgtttctca atagcaagat
     8461 ttaccgtttc agtcttaaca tcacgctcag gatcatctgg caaactagga tcaattttat
     8521 aaacgtgcgc atggtctcca tggcgtacac tcatatagtt cccatcaatt gtaatgtcct
     8581 cacgttttac tttaaaacgc tccatgtact gtttaatgag acgttctttt ctctgttcaa
     8641 gagtttctcc atccttttgt ttaagaatac gatcttccgg actttcaaat ggcttcgttg
     8701 tatcaatttc ctttaataaa acaatatgtg tgtgatctcc atgcggatac tctaatccaa
     8761 tttgaccgtc aacgatgact ttcttaaaac gtgatggctc taaattcagt tcttttgcta
     8821 agtagtccaa tttggtttga tactcagtat tttctacctc aggttgtgcc ttcttatccg
     8881 attcaacatt tggtttatac tgattcacaa gataagacca tttactcctt ttcaatgttt
     8941 caaaatgaat aagatgcaaa tgtttcccat gccttactag aatcccggtt tccgttacac
     9001 cgctgatatt ttgcccatca aacaagaaac cgtcactcgt ttgaaaatca atccccggaa
     9061 tcccttcctg ttggtgaacg ataggaagag ttggcgattg acgactatca gaggtcaatt
     9121 gtctgtgtgt cgtgccacct aagcttgatt ttaaaatata gtgataatga tccccatgcc
     9181 gaacagtata gccattggca tcctctgcga caatatcttt aggatcaaaa acgtattcat
     9241 cttcgatctg tttcgagcct gacgataatt gacttctctt aggttgagaa gaatgatttt
     9301 tttcttgata gttttcagga attaaataag cccattttgt attctttaaa tctgaataaa
     9361 agaaaaagtg cttatgatcg ccatgattga caataattcc taaatcagtt ttttcctcaa
     9421 tttgtgactc atcagtgagt aaaaaaacat catccgtcgc cttatcaatc cctggaactt
     9481 cctttttcga atctgaagga atctcttttg attgctttga ttgcgatgtt tctatgcttg
     9541 ttgttttttg atggttcgat tgctctctat agttagacgc ttgataagta accaatgcta
     9601 cagcacaaat aagcgatgct cctgctacat aaagcaaagt cttaccttgt ttcatatcta
     9661 tgtttctctc cttatttacc attattatat taccgacacg ataaatgtaa tcaactattg
     9721 taaaatagca tcaccacatc cacttattat agtcttttag tttactttta gtacgaggca
     9781 atgagccgca ggcataactg aagttaggca aggcgagttg atgaagtaac aaaagcaaaa
     9841 ctaaatgacg ataaagttaa aaccgtcgat ttatttacta gttaagtata tcactcatat
     9901 cgaaatttag caagtagtga gctactttcc aaaaataaag aacctggttc atcactacca
     9961 agttctttac atttttatac ttatttagca agttttgctt tagcagcatc tgcaagagct
    10021 gtgaaagctg ctgcatcgtt cactgccaag tcagcaagca ttttgcggtt tacttcgatt
    10081 tcggccaatt tcaaaccgtg catcaattgt gagtatgaca aaccgttcat acgagcagcc
    10141 gcattgatac gagtgatcca caatttacgg aaatcacgtt ttttctgacg gcggtcacgg
    10201 tatgcatagt agtaagagtt catgacttgt tctttcgcag tgcggaacaa gagatgttta
    10261 gctccgtagt aacctttagc taattttaaa atacgtttac ggcgtttacg agaaacaacg
    10321 ccacctttaa cacgtgccat ttaattttcc tccaaatgat aatctaaatt ctagtaagtc
    10381 ggcttatttc aaacctgtaa gcattgattt gatacgcttg aagtccccag catgtaccat
    10441 acctgcttta cgaaggtgac gacgttgttt tttagtttta ccgtggaaac ggtgtgaagt
    10501 ataagcgcgg aagcgtttca atccaccaga acctgtacgt ttgaaacgtt tagctgatgc
    10561 gcggtgagtt ttttgttttg gcatgttaat tctccttttg cttaaaaagc ttatttttta
    10621 tctgaagctg gggccaattg cataaacatt tgacgtccgt ccatcttagc gcgttgttcg
    10681 ataatggcaa tatcttgggt tgcttcagcg aactcagcta atactttcgc tccaacttct
    10741 ttgtgggtaa tcatacgacc cttgaaacgg atcgaaacct taactttatt tcctttttca
    10801 agaaatttac gggcatgacg aagttttgtc tcgaaatccc ctttatcaat aactggactt
    10861 agacgcactt cttttacagt gacaacactt tgttttttgc gttgttcttt ctgtttcttc
    10921 tgatattcaa atttgaactt accgtagtcc ataattttcg ctactggtgg tttagcttgg
    10981 ggttgaatca atactaaatc cacgttggcg ctatcagcaa tggcctgagc ctcattgagt
    11041 ggtttgatcc ccaactgttc accctcaaga ccgataagac gaacttcacg cactcggatt
    11101 tcatcattga tgaacaaatc ttgctttgct atggcttttc acctcatttt atatttttcg
    11161 agaaaaacga aacggacttg ctaaacaagt ccgcactaca ccattattct ttccgaagaa
    11221 atcttaatcc gtagagccag acaacgttag tcgcaaggcg agaagttctc acttctgctt
    11281 ttctcaatac gactattcta acatgtctaa agctacctgt caagaatttc tttcgctttt
    11341 tcggaaataa atttcactac accttcgata gatactcctg ttgtatcaaa ggtaatagca
    11401 tcatctgctg cctttaaagg agaaacttct cgattggaat ctttatagtc acgagccgca
    11461 atctcctctt tcaaggattc caagtctgtc tcaatgccac gttccgtatt ttccttaaat
    11521 cgacgaaggg cacgctcttc aacagaggca acaaggaata ttttgagttc tgcttgcggc
    11581 aatacaaccg taccaatatc acgaccatcc ataacaatcc caccagcttg cgcaatgtcc
    11641 tgttgcaggc ggaccaattc ttcccgtact agaggaagcg ctgctaccgc tgatacatta
    11701 tttgttactt gattatctcg aataggcaaa gtaacatcct catcaccgac aaaaacaagt
    11761 tgctgaccgt tttcatcccg cccaaatcga atgggatact gggcaagcaa gtccacgatt
    11821 ctattttgat ctgtgacctc tatgccgttt gtcaaggcta gataggtagc cgagcgatac
    11881 atagctcctg tatctaagta agtatatccc aaatttttag caataatttt agcgaccgtt
    11941 gactttccac ttgaagctgg accgtcaatt gcaatttgaa ttgatttcat aactcctctt
    12001 tatctaatac gaactacatc cccaggatga gcaatccaag accctgtagt cattttctct
    12061 ggattcaaac gctctagctc tgcaattgaa atcccaccac gagcagccag ttgtcctaca
    12121 ccttcacctg cttgaacagt aagggtagag ccatccgttg cttccgctgg gctagaactt
    12181 gtttctgttt ctgtcgtgtc agtcgaagta gattcttgtg tctcagcagc cgatgaagag
    12241 ctctctgcta cgactgttgt agtgcttggg gtataaaatt cttttgttga atctgtttta
    12301 ctaccgccac cgattgagag atagacagcc ataattccaa taatcagtac gataacaaag
    12361 aaaataattg ccaaaactgt aaatactgtt gtattcgcta cccccttact caaacgttct
    12421 ttacgactag ttgtttctgt gtggtaaact tcttcattcc atggctcttg tgacattatt
    12481 gagaaaactc cttgtatttt tattaaaata tgattacaat actaatatga aagtaaaact
    12541 tattcctgaa cggtgcattg cttgcgggct ctgccaaacc tactcatctc tattcgatta
    12601 tgatgacgac ggtatcgttg ttttttcaga cgactcacaa tttgagaaaa cgattgaacc
    12661 caatccagat attctcaaag ccatcaaatc atgtcctaca aaagccattt cagcggattg
    12721 atttggcttt ttttgtataa tactcttcaa aataatcctg ttttattaaa tggtctatta
    12781 attcaatttt acccttgaag caactatgaa tagctaaatg gttaataaag tatttttttg
    12841 tccatttacg catataatac attcgtccgt tgggaaattc ttttgcaaat atacgaatgg
    12901 ctaaataaga aacttcaatt ttttctatgg tagcaatttc aattttctgc actgcaaaag
    12961 gattagccga agcaatccgt aaatgctcat cttttatctc gaaatagcga tgtaagccga
    13021 gcactactaa tacagcaaag agtgagacaa gtagaataaa taatcttgaa acttgcaact
    13081 tctccaataa aagtgccata ccaataaaaa taggtgtgaa ggtaagtgac cagtatatga
    13141 tggcccatga taaatccggt tgccaatggt aacgaatttt accaaaaatt ttga
//
LOCUS       DBNFCO010000054        13110 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.054, whole genome shotgun sequence.
ACCESSION   DBNFCO010000054 DBNFCO010000000
VERSION     DBNFCO010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 13110)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13110)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13110
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.054"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            <1..228
                     /locus_tag="AC1PIV_001401"
     CDS             <1..228
                     /locus_tag="AC1PIV_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HIP6612420.1"
                     /translation="NPYARKILFKCIHNIASANHTNPCHIADFYKKRKRQSQTTSTKL
                     HTIASIHRLIRTMYYLIMHNKFYDYASTQNR"
     gene            complement(430..1086)
                     /gene="phoU"
                     /locus_tag="AC1PIV_001402"
     CDS             complement(430..1086)
                     /gene="phoU"
                     /locus_tag="AC1PIV_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HIP6612421.1"
                     /translation="MLRAQFEEELGKLHNQFYAMGNEVLAQINNAVRAFTIHDRELAK
                     EVIEADKKINAFEVKLEKKSLEIIALQQPVSTDLRRVITVLKATSDLERMGDHAVSVA
                     KAAIRMKGEVRIPVVEEEIKKMGREVRQLVEETLELYLGDADMERAYEVAARDEVVNE
                     FYSTIQELTTEEIKKNPESLVAGRDYYQVLTYLERVGDYAKNICEWVVYLRTGDITEL
                     "
     gene            complement(1115..1873)
                     /gene="pstB"
                     /locus_tag="AC1PIV_001403"
     CDS             complement(1115..1873)
                     /gene="pstB"
                     /locus_tag="AC1PIV_001403"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HIP6612422.1"
                     /translation="MTSPILQVKDLSVYYNKKKALNNVSIDFYPNEITALIGPSGSGK
                     STLLRSINRMGDLNPEVTLTGAIDYNGKNIYSPRTDTVDLRKEIGMVFQQPNPFPMSI
                     YENVVYGLRINGIKDKQVLDEAVERSLIGASIWNEVKDRLHDSAVGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEDTLYGLKDKYTMVLVTRSMQQASRISDRTG
                     FFLDGDLIEYNLTKEMFLNPANKETEDYITGKFG"
     gene            complement(1885..2688)
                     /gene="pstB"
                     /locus_tag="AC1PIV_001404"
     CDS             complement(1885..2688)
                     /gene="pstB"
                     /locus_tag="AC1PIV_001404"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HIP6612423.1"
                     /translation="MADYNWNERHIITFPEENIALSTKDVHVYYGKNEAIKGIDMQFE
                     KNKITALIGPSGCGKSTYLRSLNRMNDTIDIAKVTGQILYEGIDINRPDMNVYEIRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLKQAALWDQVKDDLHKS
                     AFTLSGGQQQRLCIARAISVKPQILLMDEPASALDPIATMQLEETMFELKKDYTIIIV
                     THNMQQAARASDYTAFFYLGDLIEYDKTANVFQNAKLKSTSDYVSGHFG"
     gene            complement(2713..3600)
                     /gene="pstA"
                     /locus_tag="AC1PIV_001405"
     CDS             complement(2713..3600)
                     /gene="pstA"
                     /locus_tag="AC1PIV_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HIP6612424.1"
                     /translation="MHAKKFDKLATGILYSIAGVIVVILTSLILYILLRGLPHVSWDF
                     LTSKSSSYKAGGGIGIQLYNSFFLLVVTLLISVPLSTGAGIYLAEYAKKGPLTNFIRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSILSGALALTVFNLPQMTRNVEDSLRHVH
                     HTQREAGLALGLSRWETVLHVVIPEALPGIVTGIVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNPLSVTSPISIFRQSETLAVHIWKVNSEGTIPDATQVSAGSAAILLVFILIF
                     NLSARYIGKKLHAKLTSAA"
     gene            complement(3590..4507)
                     /gene="pstC"
                     /locus_tag="AC1PIV_001406"
     CDS             complement(3590..4507)
                     /gene="pstC"
                     /locus_tag="AC1PIV_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HIP6612425.1"
                     /translation="MKNEQLAKELSSPSKNSRLEKFGKVITFLCLSLIVFIVAMILIF
                     VAQRGLSTFFVDGVSITDFLFGSKWEPSSKIFGALPMISGSFIVTILSAVVATPIAIG
                     AAVFMTEISPKRGAKILQPVIELLVGIPSVVYGFIGLQVVVPFVRSIFGGTGFGILSG
                     VFVLFVMILPTVTFMTVDSLRAVPRHYREASLAMGATRWQTIWRVILNAAKPGIFTAV
                     IFGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSVLTMGIGNTVMGTVQNNVLWS
                     LALVLLLMSLIFNMIMKFITREGKKNYAR"
     gene            complement(4510..5379)
                     /locus_tag="AC1PIV_001407"
     CDS             complement(4510..5379)
                     /locus_tag="AC1PIV_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042301 - phosphate ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HIP6612426.1"
                     /translation="MKKKQKLGIAALFLLSSMALSGCSSWIDRGESITAVGSTALQPL
                     VEAAADEFGSVNIGKSINVQGGGSGTGLSQVQSGAVQIGNSDVFAEEKDGIDASKLVD
                     HQVAVAGLAVIVNEQVSVKDITTEDLRKIFTGEITNWKELGGKDLEISIINRAASSGS
                     RATFDSVIMDGQTATQSQEQDSNGMVKSIVAQTPGAISYLSFAYLDDSVKTIKLNGFE
                     PTAENVATNDWPIWSYEHMYTMGKATDLTEEFLDYMMSDEVQNGIVESMGYISINDMK
                     VVKSADGTVTEKE"
     gene            complement(5517..6818)
                     /locus_tag="AC1PIV_001408"
     CDS             complement(5517..6818)
                     /locus_tag="AC1PIV_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HIP6612427.1"
                     /translation="MQLPQDFIDKYNHLLGSEAQAFFESFEQDPISGFRTNPLKESQL
                     DFEQPIPNMTWSYYGKVSGKSPEHVTGLVYSQEPAAQVVGQIAAPKKGMKVLDLAAAP
                     GGKSTHLLSYLENTGLLVSNEISNKRARILAENIERFGARNVVVTNESADRLEKVFPG
                     YFDMIVLDAPCSGEGMFRKYPDAIQYWSKHYPAQCASLQREILESALNMLAPDGQLIY
                     STCTWSPEENEEVVTWLLEQYDLELIDIPKINGMVEGIGYTEVARMYPHHFAGEGQFV
                     AKFRFLGEASQKKLKPGKSNLNREQQSLWKEFEQKHLRVQLDGLLQVFGDNLYLLPHG
                     LPDLSKVKIARNGLHLGTYKKKRFEPSFALGLALHSSEVENRVEISLEEFSSYTAGHT
                     IAVSKDLANGWYQVAVQGNGLSFAKIVSGTLKNGFPKGLRF"
     gene            complement(6818..7576)
                     /locus_tag="AC1PIV_001409"
     CDS             complement(6818..7576)
                     /locus_tag="AC1PIV_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HIP6612428.1"
                     /translation="METKYHFAQTIVLEAGNFLRQHLHDDLQIEEKGDFTDLVTHLDK
                     QVQEMLTQQIQSRYQGDGILGEEGGDVSSIHEGNVWVIDPIDGTTNFIAQKTDFAIMI
                     AYFENGVGKFGIIYDVMRDKLFHGGDSFPVFCNQERLKKPELRPLRQSLIGINAKLYA
                     GNAHGVAELANQSLGTRSVGSAGIGFAHVLEGRLFAYASYLCPWDYAAASIIGSSLGL
                     VMLSFEGPSLAYDKREFVMLVSESHLEEVKGYIF"
     gene            complement(7566..7844)
                     /locus_tag="AC1PIV_001410"
     CDS             complement(7566..7844)
                     /locus_tag="AC1PIV_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HIP6612429.1"
                     /translation="MNKNYSYPLDFSWSTEEISSVLSFLNQVEAAYEKGADAVAILAS
                     YKSFKDVVKSKGQERQIDRDFEAVSGYSTYRVVKAARDKGKGVICFGN"
     gene            complement(7859..8260)
                     /locus_tag="AC1PIV_001411"
     CDS             complement(7859..8260)
                     /locus_tag="AC1PIV_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004246303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HIP6612430.1"
                     /translation="MITLFLSPSCTSCRKARAWLTSHEVPFIEHNIMTSPLTAEELKN
                     ILALTENGTDDLISTRSKVFQKLDIDVDELSVKQLIGLIETYPSLLRRPIILDEKRMQ
                     IGFNEDEIRAFLPRKYRKQELKNATLRAEIG"
     gene            complement(8335..9081)
                     /locus_tag="AC1PIV_001412"
     CDS             complement(8335..9081)
                     /locus_tag="AC1PIV_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005216 - monoatomic ion channel activity
                     [Evidence IEA];
                     GO_function: GO:0005267 - potassium channel activity
                     [Evidence IEA];
                     GO_process: GO:0034220 - monoatomic ion transmembrane
                     transport [Evidence IEA];
                     GO_process: GO:0071805 - potassium ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HIP6612431.1"
                     /translation="MLKRLIRHPFYEKAMTYIAVVYVFLIVLELMDASIANSSGYRVL
                     DLLLWFIFVCDYFAQLYYADDILEYVQGHILELIAIIPFDSFFSFLRLGRLARLFRLV
                     KVTRIFALSNRFWDTINKLLHTNSLSKVLMLNISAVLVSSVLLSVIEGKSFFDALWWS
                     IVTMTTVGYGDIVPQDTISKIIAILLMLVGICTFGMVTSTITRFFSETERETKLDILM
                     AKIDEQNETLLRLEKKIESLGKLGELQGRD"
     gene            complement(9074..9997)
                     /locus_tag="AC1PIV_001413"
     CDS             complement(9074..9997)
                     /locus_tag="AC1PIV_001413"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014917251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003919 - FMN adenylyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HIP6612432.1"
                     /translation="MNIRTIKHYSELNQEEPTVLVLGYFDGLHLGHKALLDRARKVAD
                     EQGLTVTVLTFPESPRLAFSRFSPELLLHLTSQEQRYLLLKKYGVDNLILTDFTSEFA
                     NNTPQQFMERYIKGLNAQILVAGFDYHFGNCRADVKDLTELFDGQVEIVSEVSLGGEK
                     VSSTRIRQAIQSGDVSLANQLLGYPFMTEGIVVHGDARGRTIGYPTANLAPFDRVHLP
                     SEGVYVADVEVDGKRYRAMTSVGKNVTFDGTEMRIEAHIFGFHRFIYGEKITIFWLEK
                     IRDMVKFDGIEGLMEQMKSDEKFALQWGKYA"
     gene            complement(10032..10910)
                     /gene="truB"
                     /locus_tag="AC1PIV_001414"
     CDS             complement(10032..10910)
                     /gene="truB"
                     /locus_tag="AC1PIV_001414"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HIP6612433.1"
                     /translation="MISGIINVKKEAGMTSHDVVFKLRKILQEKKIGHGGTLDPYVTG
                     VLPIAVGKATRMIEYMQEEGKIYEGEITIGYSTTTEDASGDLVERTPVLYIAEQAVDE
                     AMTSFVGTITQIPPMYSAVKVKGRKLYEYARAGEEVERPQRQIEIYSFERTSPIELAD
                     DCARFTFRVRCGKGTYVRTLSVDLGAKLGYASHMSKLERTGSAGMDLADALTLEEISS
                     LVAENDFSFLQPIERGIGDLPVVELKEEQVQDATFGRFVELNAEAERLAGFHDGQLIA
                     IFEKRDQLYKPSKVLV"
     gene            complement(10960..11169)
                     /locus_tag="AC1PIV_001415"
     CDS             complement(10960..11169)
                     /locus_tag="AC1PIV_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612434.1"
                     /translation="MDWPTIKIGDEGYYDAPLIFSWGYDEEAEESIDEAVAYEAAPSG
                     TMRRIHKELENLIGTTFGSYRFYDD"
     gene            complement(11141..11392)
                     /locus_tag="AC1PIV_001416"
     CDS             complement(11141..11392)
                     /locus_tag="AC1PIV_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612435.1"
                     /translation="MKQFERTYENIDFILFKAYYIEGKSVDVAVSLREQEYMIEYIGA
                     DNRVENSVDYTSIRISKAKKFREFLKGNQAVGLADHKNW"
     gene            complement(11419..12655)
                     /locus_tag="AC1PIV_001417"
                     /pseudo
     CDS             complement(11419..12655)
                     /locus_tag="AC1PIV_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018364639.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
     gene            complement(12652..12885)
                     /locus_tag="AC1PIV_001418"
     CDS             complement(12652..12885)
                     /locus_tag="AC1PIV_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HIP6612436.1"
                     /translation="MNTIDLNLPVAEIINQHPEVKDILVELGFKPLANPAMLNTVGKV
                     TSLKTGSKMTKIPLDRIQQVLECNGYEVIGGEA"
     gene            complement(12898..>13110)
                     /locus_tag="AC1PIV_001419"
     CDS             complement(12898..>13110)
                     /locus_tag="AC1PIV_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histone acetyltransferase"
                     /protein_id="HIP6612437.1"
                     /translation="DAICQLASEFTDTVGIGVGLNANYGKAQRLYVKHGFIPDGSGVW
                     YRGCSLPVGAKAYNDDELALYFTKKL"
BASE COUNT         3869 a         3026 c         2365 g         3850 t
ORIGIN      
        1 aatccctacg ctagaaagat tctgttcaag tgtatccaca atatcgcttc agccaatcat
       61 accaatcctt gccatatcgc agacttttat aagaaacgaa aaagacaatc gcaaacgact
      121 tcaacgaagc tgcacacgat tgcctccata catcgtctca ttcggacaat gtattacctc
      181 attatgcata acaaatttta cgattacgct tcaacccaaa atcggtaaaa ctgtttatgc
      241 tctatcattg taacacctta tcaaaaaatt tcaacataag gtgttggttt tgtatgcact
      301 ttttacacgt aactttagtc caaaataaaa caatttcctt atttggatga cgagacacaa
      361 aatatttttc gtcaaatacc ttgatgaact tgacaaatgg tagaaaagaa gccctctcgg
      421 acttctgaat tacaactctg taatatcacc tgtgcgtaga taaacaaccc actcacaaat
      481 atttttagca taatcaccga cacgttccaa gtaggttaaa acttggtaat agtcgcgacc
      541 agcaaccaag gattctggat tcttcttgat ttcttccgtt gtcaattctt gaatagttga
      601 atagaattca ttgacaacct catcacgtgc tgctacttca taagcgcgct ccatatcagc
      661 atcacctaag tagagttcca aagtttcttc tactaattga cgaacttcac gtcccatttt
      721 cttgatttct tcttcaacaa ctgggatgcg aacttctccc ttcatacgga tagctgcttt
      781 agcaactgag actgcatggt ctcccatacg ctccaaatca ctagttgctt ttaagactgt
      841 gataacgcga cgaagatctg ttgagacagg ttgttggaga gcaatgattt caagtgattt
      901 tttctctaat ttcacttcga aagcattaat tttcttatct gcttcaataa cttcttttgc
      961 taattcacga tcatgaattg taaaggcacg aacagcatta ttaatctgag ccaatacttc
     1021 atttcccatg gcgtaaaatt ggttatgaag ttttcctaat tcctcttcaa attgagctct
     1081 taacatgtga acctctttct ttttcttata ggccttagcc gaacttacct gtaatatagt
     1141 cttctgtttc tttattggca ggattcaaga acatttcttt tgtcaaattg tattctatca
     1201 aatcgccatc aaggaagaaa cctgttcgat ctgaaatacg tgatgcctgt tgcatagaac
     1261 gtgttactag caccattgta tacttatctt tcagaccata aagtgtgtcc tcaattttac
     1321 cagctgagat cgggtcaagg gctgaagttg gctcatccaa caaaataatt ttggggcttg
     1381 ttgccaatac acgggccaca catacacgtt gctgctgacc acctgaaagt ccaactgctg
     1441 agtcatgcaa gcgatctttc acttcattcc aaatagaagc accaatcaag gaacgctcaa
     1501 ctgcttcgtc caagacctgc ttgtccttga taccgttaat acgtaaacca taaacgacat
     1561 tctcgtagat agacatcggg aatgggtttg gttgttggaa taccataccg atttccttac
     1621 gaagatcaac agtatccgta cgaggactgt atatgttctt tccgttgtaa tcaatcgcac
     1681 ctgtcaatgt tacctctggg tttaaatctc ccatacggtt aatagaacgc aagagggttg
     1741 acttaccaga accagagggt ccaatcaaag cagtaatttc atttggatag aaatcgattg
     1801 acacattatt caaggctttt ttcttgttat agtaaacaga caaatctttt acttgtaaaa
     1861 taggtgatgt catttgtttc ctttctatcc aaaatgtcct gaaacgtagt cactagttga
     1921 cttgagtttt gcattctgga agacatttgc tgtcttatca tattcaatca agtcacccag
     1981 atagaagaaa gctgtgtaat cacttgcacg agctgcttgt tgcatattgt gcgtaacaat
     2041 gataatggtg tagtccttct tcaattcaaa catagtttct tctaactgca tagtcgcaat
     2101 tggatccaag gctgatgcag gctcatccat aagcaagatt tgtggtttta cagagatagc
     2161 tcgtgcaata cacaaacgct gttgctgtcc acctgataag gtaaaggctg acttgtgcaa
     2221 gtcatctttt acctgatccc aaagggctgc ttgtttcaga gaagtttcaa caatctcatc
     2281 caaaacctgc ttatctttca cacctgcacg ttcatgtgcg aatgtgatgt tgcgataaat
     2341 cgattttgca aatgggttgg gacgttggaa taccattccg atatgcttac gaatttcgta
     2401 aacgttcata tctggtctat tgatgtcgat tccttcataa agaatttgac cggttacctt
     2461 agcaatatca atagtatcat tcatacgatt aagactgcga agataggttg atttcccaca
     2521 ccctgatggt ccaatcaagg ctgtaatttt atttttttcg aactgcatat caatgccctt
     2581 gattgcttca tttttaccat agtaaacatg aacatctttt gtcgaaaggg cgatattctc
     2641 ctctggaaaa gtaatgatat ggcgttcatt ccagttgtaa tctgccattt tttctcctta
     2701 taagtcagac ttctaggctg ctgaagtcag tttcgcatga agtttcttac caatataacg
     2761 tgcagaaagg ttgaaaatca agatgaagac caagagaatc gctgctgaac cagcagaaac
     2821 ttgggttgca tctggaattg taccttcgct gtttaccttc cagatatgaa ccgcaagggt
     2881 ttctgattga cggaagatag aaatcggact agtaacactc aatggattcc agtttgacca
     2941 gtcaagagct ggagctgact gaccagccgt gtagataaga gctgctgcct caccgaagat
     3001 acgaccagat gccaagacga tacctgttac aatccctgga agtgcttctg gaataacaac
     3061 atggagaaca gtttcccaac gtgatagacc aagagccaat cctgcttcac gttgtgtatg
     3121 gtgaacgtga cgaaggctgt cctctacgtt acgtgtcatc tgtggtaagt tgaagactgt
     3181 aagagccaag gcacctgata agatagaaaa accgtactca aactgaacaa cgaaaatcaa
     3241 gtaaccaaac aaaccaacga caacggaagg tagggatgac aaaatctcaa tacaggtacg
     3301 gataaagtta gtcaatggac cttttttagc atattcagcc aaataaatac ctgcaccggt
     3361 tgacaaggga acagaaatta agagcgttac aaccaatagg aagaatgagt tgtagagctg
     3421 aattccaata ccaccaccag ctttgtaaga cgaagattta cttgtcaaaa aatcccagct
     3481 tacatgtggc agaccacgta gcaagatgta aagaatcagt gacgtcaaga taacgacaat
     3541 cacaccagcg attgagtaaa gaataccagt cgccaattta tcaaattttt tagcgtgcat
     3601 agtttttctt accctctctc gtaataaatt tcataatcat gttaaagata aggctcatca
     3661 agagcaagac tagggccaag gaccatagga cgttgttctg aacagttccc ataactgtat
     3721 taccgatacc cattgtcaaa acagaagtca aagtcgctgc tggcgttgtc aaggaagtcg
     3781 ggataaccgc agagttcccc actaccatct gaatagccaa ggcttcacca aaggcacgcg
     3841 ccataccaaa gataacggcc gtaaaaatac ctggcttagc cgcgttcaaa ataacacgcc
     3901 aaatcgtctg ccaacgagtg gctcccatag ccaaacttgc ttcgcggtag tgacgaggta
     3961 ctgcacgtaa actgtcaacc gtcataaagg ttactgttgg caaaatcata acgaaaagta
     4021 caaatacacc cgacaagata ccgaaacctg ttccaccgaa gattgaacgt acaaatggca
     4081 caactacttg caaaccaatg aaaccgtata caaccgatgg aataccaacc aaaagttcga
     4141 taacaggttg taagattttt gcaccacgtt ttggtgatat ttctgtcatg aagaccgctg
     4201 caccgattgc gataggggtc gcaacaacag ctgacagaat cgtaacaatg aaagaacctg
     4261 aaatcattgg cagggcacca aatattttcg agcttggttc ccacttgctt ccaaataaga
     4321 aatcagtgat gctcacaccg tcaacaaaga aagtcgataa tccacgctgt gcaacgaaaa
     4381 tcaaaatcat tgcaacaata aagacaatca atgatagaca aaggaatgta attaccttac
     4441 caaacttctc taatcgagaa tttttagatg gagacgataa ctcttttgct agttgttcgt
     4501 ttttcatgct tactccttct cagtcaccgt gccatcagca cttttcacaa ctttcatatc
     4561 gttgatagaa atgtatccca tactttcaac gataccattt tgaacttcat ctgacatcat
     4621 gtaatctaaa aattcttctg tcaaatcagt cgcttttccc atcgtataca tatgctcata
     4681 ggaccaaatt ggccaatcat ttgttgctac attttcagca gttggttcaa aaccgtttaa
     4741 cttaattgtt ttaacggaat catctagata agcaaatgat aggtaggaaa ttgcacctgg
     4801 tgtctgagca acaatagatt ttaccatacc gttagaatct tgttcttgac tctgagttgc
     4861 ggtttgtcca tccatgataa cactatcaaa ggtcgcacgt gaacctgaac tagctgcacg
     4921 gttaatgatt gaaatttcca aatccttacc gcccagctct ttccagttgg taatctcacc
     4981 tgtaaaaatt ttacgcagat cttctgtagt aatatcttta accgatacct gctcatttac
     5041 aataacggcc aaaccagcta ctgctacttg atggtcaaca agtttacttg catcaatacc
     5101 atctttttcc tcagcaaata cgtcagagtt accaatctga acagctccag actgaacttg
     5161 tgacaagcca gtacctgacc ctcccccctg aacgttgatg gatttaccga tattgacact
     5221 accaaattca tctgccgctg cctcaacaag tggttgaagc gccgtcgaac ctacggctgt
     5281 aatagactct cctcgatcga tccaagaaga acaaccagaa agagccatac tactcaaaag
     5341 aaacaaagct gcaattccaa gcttctgctt ttttttcatt tcattttttc ctttacattt
     5401 ttcagtggaa tctcctaaaa ttaactctgt attttacata gaatttacaa gatatttcca
     5461 ctcatccact atatcatata aaaagacaag ttgcaaaaaa aatttgctga tttattttaa
     5521 aatctcaacc cttttggaaa gccgttttta agcgttccag atacaatttt tgcgaaacta
     5581 agaccgttcc cctggactgc tacctgatac cagccattag ctaaatcctt ggacacagct
     5641 atggtatgtc ctgcagtata ggacgagaat tcttctaagc tgatttccac tcgattttca
     5701 acctccgaac tatggagtgc tagacctaaa gcaaaacttg gttcaaatct ttttttctta
     5761 tacgtcccca agtgaagacc atttcgagca atctttactt ttgacaaatc aggaaggccg
     5821 tgtggcagta ggtagagatt gtcgccaaaa acctgcagta aaccatccaa ttgaaccctt
     5881 aaatgcttct gttcaaattc tttccagaga gattgttgtt ctctattcaa attagatttt
     5941 cctggtttta attttttctg actggcttcc cctagaaatc taaatttggc aacgaactga
     6001 ccttctcctg caaaatggtg gggatacata cgagcaactt ctgtatatcc gattccttct
     6061 accattccat tgattttagg aatgtctatt agttccaaat catactgttc taagagccaa
     6121 gtcactactt cttcattttc ctctggtgac caagtgcaag tagaataaat caattgacca
     6181 tctggagcca acatgttcaa ggccgattct aaaatttcac gctgtaagct tgcacattgt
     6241 gctggataat gtttggacca atattgaatc gcatcggggt attttcgaaa catcccttca
     6301 cctgaacagg gagcgtctag gacaatcata tcgaaatatc ctggaaagac cttttccaag
     6361 cggtctgctg attcatttgt tacaacaaca ttcctcgctc cgaaacgctc aatattttca
     6421 gccaatatcc ttgctcgttt gttagaaatt tcattactaa ccaagagccc cgtattttct
     6481 aagtatgaaa gcaagtgagt agactttcct cctggcgctg ctgccaagtc caatactttc
     6541 atcccttttt tcggtgctgc aatctgacct acaacctgtg cagctggctc ttgtgagtag
     6601 actaagccag ttacatgttc tggagatttc cctgagacct taccatagta tgaccaagtc
     6661 atattaggga ttggttgctc aaagtccaat tggctttctt taagaggatt tgtgcgaaat
     6721 cctgagattg ggtcttgttc aaaactctca aaaaatgctt gggcttcact accaagcaaa
     6781 tgattatatt tatctataaa atcctgtggt aattgcatta gaatatatac cccttcactt
     6841 cctcaagatg ggattctgat actagcatga caaactctcg cttatcatag gccagactcg
     6901 gaccctcaaa acttaacatg actaagccta aagaggaacc aataatactg gctgctgcgt
     6961 agtcccatgg acacagataa gaagcatagg caaataatct tccttccaga acgtgggcga
     7021 aaccaattcc agcacttcct acagatcttg tacctaaact ttgatttgct aattctgcca
     7081 ctccatgtgc attgcctgcg tacaactttg cattgattcc tatcaaactc tggcgaagag
     7141 ggcgcagctc tggtttcttt aagcgttctt gattgcaaaa aacagggaat gaatctcctc
     7201 catggaaaag tttgtctcgc atgacatcat agatgatacc gaactttcct actccatttt
     7261 caaaataggc aatcataatg gcaaaatcag ttttctgagc aataaaattt gtggtgccat
     7321 caattggatc aataacccaa acatttccct catgaataga agaaacgtcc ccaccttcct
     7381 cgcctaaaat cccatcacct tgatagcgag attgaatctg ttgagtcaac atttcttgca
     7441 cttgtttatc aaggtgtgtt accaagtctg taaagtcacc tttttcttca atctgaagat
     7501 catcatgtaa atgctgtcgg agaaaatttc cagcttccag gacaatcgtt tgggcaaagt
     7561 gatacttagt ttccaaaaca aataactcct ttccctttat ctcgagcagc cttaacaact
     7621 cgataggttg aataaccaga aactgcttca aagtcacgat caatttgacg ttcctgtccc
     7681 ttacttttaa caacatcttt gaagctttta taactagcta atatagctac cgcatctgct
     7741 cctttttcat aagctgcctc cacctgattc aaaaaagaaa gcacggagga aatctcctct
     7801 gtgctccacg aaaaatcaag tggatatgaa taatttttgt tcatatcttt tatctttctt
     7861 atcctatttc tgctctcaat gtagcatttt ttagttcttg tttgcgatac ttccgcggaa
     7921 gaaatgcacg aatttcatct tcgttaaaac caatctgcat ccgcttctca tccaaaataa
     7981 tcggacgccg taagagactc ggataggttt cgattaaccc aataagctgc ttcacagaaa
     8041 gctcatcaac atcaatatct agtttctgaa aaacttttga acgggtagaa atcaagtcat
     8101 ctgtcccatt ttctgtcaat gctaaaatgt tctttaattc ctcagcagtt agagggctag
     8161 tcataatatt gtgctcaata aaagggactt cgtgacttgt cagccaagca cgagctttac
     8221 gacaactggt acaactcggt gacaaaaata aagtaatcat gtcttccatc ccctctaaaa
     8281 acatttttct tcttattatt atactctaac ttaaaagagt tttcaatagt aaatctaatc
     8341 tcttccctgt aattcaccta attttcctaa agattctatt tttttctcta agcgtaataa
     8401 tgtttcgttt tgttcatcaa tttttgccat caagatatcc aacttcgttt ctcgctctgt
     8461 ttcagagaaa aaacgagtta ttgtggaggt aaccatacca aaagtacaaa taccaaccaa
     8521 catcaagagg atggctataa ttttagaaat cgtatcttgg gggacaatat ctccataccc
     8581 tacagttgtc atcgttacaa tggaccacca aagtgcatcg aagaatgatt ttccttcaat
     8641 tactgataat aagacacttg aaactagcac tgctgagata tttaacatca acactttgga
     8701 taaactgttg gtatgcaaaa gcttgttgat tgtatcccag aatcgattag acagggcaaa
     8761 tattctcgtt actttgacca atctgaagag tcgtgcaagt cttcccaagc gaagaaaact
     8821 gaagaatgaa tcaaatggaa taatggcaat taattccaag atatgtccct gtacatattc
     8881 aagtatgtca tccgcataat aaagctgagc aaaataatcg caaacaaaaa taaaccataa
     8941 gagcaagtct agtacccgat acccactaga attggcaata ctagcatcca ttaattcaag
     9001 tacgataaga aatacataga ctacagctat gtaggtcata gccttctcat aaaaaggatg
     9061 acgaatcaat cgtttaagca tatttccccc attgcaaggc aaatttctca tcagatttca
     9121 tctgctccat caatccttca attccatcaa atttgaccat atctcgaatt ttttcaagcc
     9181 aaaaaatagt tattttttct ccgtagataa agcggtgaaa cccaaaaata tgggcttcta
     9241 tccgcatctc cgttccatca aaggtcacat ttttcccaac gcttgtcata gctcgatagc
     9301 gttttccatc tacttcgaca tcagcgacgt agactccctc agatggtaaa tggacacggt
     9361 caaaaggagc cagatttgca gtcggatagc cgatggtgcg tcctctggca tctccatgca
     9421 ccacaattcc ctccgtcata aatggataac ctaaaagttg attagctaga gagacatccc
     9481 ctgactggat agcctgacga atacgagttg acgaaacttt ctctccgccc aggctcactt
     9541 cacttacaat ttctacctga ccatcaaata actctgtcaa atctttgaca tctgctctgc
     9601 aatttccaaa atgatagtcg aaacctgcaa ccaaaatctg ggcattgaga cctttaatat
     9661 agcgctccat aaactgctga ggagtattat tagcaaattc actagtaaaa tcagtcaaaa
     9721 taagattatc aacaccatat tttttcaata agaggtagcg ctgctcttga ctagtcaaat
     9781 gcagtaaaag ttctgggcta aagcgagaaa aagccaatcg aggtgactct ggaaaggtca
     9841 gaacagttac tgtcaaacct tgctcatctg ctacttttct tgctcgatca agtaaagctt
     9901 tgtgcccaag atgaagccca tcaaagtagc ccagtactaa aaccgtcggc tcctcttgat
     9961 tcaattcact ataatgttta attgttctaa tgttcatgtt ttctatttta tcacagttat
    10021 tgagaaattt cttagaccaa aaccttgctc ggtttataca gctggtcgcg tttttcaaaa
    10081 atagcaatca actgaccatc atgaaagcct gctaagcgct ctgcttctgc attcaattcg
    10141 acaaatcgac caaatgtagc atcttgcacc tgctcttctt tcaattctac aacaggtaaa
    10201 tccccgatac cacgttcaat aggttggagg aatgaaaaat cattttcagc taccagcgaa
    10261 gaaatttctt ctaaagtcaa ggcatccgct aggtccattc cagctgatcc tgttcgttcc
    10321 aacttggaca tatggctggc atagcccaac ttagccccta ggtcaacaga cagggtgcgg
    10381 acataggtgc ccttaccaca gcgaactcgg aaggtaaacc gtgcacagtc atctgctagt
    10441 tcaatcgggc tagtccgttc aaaactgtaa atctcaattt ggcgttgagg acgttcaact
    10501 tcttcgcccg cccgtgcgta ttcgtagagt ttacggccct tgaccttgac agcagagtac
    10561 ataggcggaa tctgggtaat agtgcctacg aaactggtca tagcctcatc aactgcctgc
    10621 tctgctatgt acaaaaccgg tgtccgctca acaagatcgc cagatgcatc ttctgtcgtg
    10681 gtagagtaac caatggtaat ctccccctcg taaatcttgc cctcttcctg catgtactca
    10741 atcatgcgcg tggccttgcc gactgcaatg ggcagaacac ctgtcacata tggatccaag
    10801 gtcccaccgt gaccaatctt cttctcctgc aaaatcttgc ggagcttaaa aacaacatca
    10861 tgcgaggtca tacctgcctc tttttttaca ttaataattc ctgagatcat gttctcatta
    10921 taacacaaag gaccgctctt gtgggcggtc cggtatcaat cagtcatcgt agaaacgata
    10981 gctaccgaat gttgtaccta tcaaattctc tagttcctta tgaatacgtc gcatggttcc
    11041 agaaggtgct gcttcatatg caactgcctc atcaatgctt tcctcagcct cctcatcata
    11101 gccccaagaa aatatcaatg gggcatcata atagccttcg tcaccaattt ttatggtcgg
    11161 ccaatccaac agcttgattt cctttcaaaa attctctaaa tttttttgcc ttgctgatac
    11221 gaatagaagt gtaatctact gaattctcaa ctcgattatc tgcacctata tattcaatca
    11281 tatactcctg ctccctaaga ctgaccgcaa catctacgct ctttccttca atataataag
    11341 ccttaaaaag aataaagtca atattctcgt atgtacgttc aaattgtttc atgttctttc
    11401 ctttcaaaaa tgactaaact agatatcccg atgaaaatcg ctatcaatct caaaaaatgg
    11461 ttgaatatcc tgaacatact ccaaaacgcc ttgaaactct ccttggtcat cacgcaccgc
    11521 cttatagact acatagacaa acttgcccat gctctcggac ttgaaccaca tggcgtccaa
    11581 tctggcttgg tgttcgtttg aaaatcatgt cttcgacagg gtggctgtca ttgtaatatt
    11641 ggaaaatgtc atccttgttg acaaaggtta attccagcgg taaatgattg aggataagat
    11701 tcgcttgctc aacagataaa taaccattgc cgaaggtctg cggactagtt ctgtcctgaa
    11761 cagtttctga cttttccttg ggtgtgaagg caatggtaaa ctggccttct ggcgtgtcga
    11821 taatctgctg atttggtcct gctggctgca gagaaacagc atttacttcc tgctctgcta
    11881 tttcccaaaa agcctcccga tgaggtaccc acttggctgt cggcttgaca atggcgtagc
    11941 cgtaggcgtc actgtctact gccacttgga gccagtcgtc ctgggtgaaa atctccagca
    12001 aaatcatgag aagtatggct tcttccttga aaatcatctc ctcgaactcc ttggcgaagt
    12061 tttcaaagtg agcacgtgtc gcagctaggt cacctccttc aagtgcctta cgggccgtct
    12121 tgaagagatc gcgaatctcg tcgtccacac cccacatgac cttgggcggt gcatcataac
    12181 cgtaccgctc cataatggga aagaagacct tttccttgcg ggtatagtgg ttttcaaatt
    12241 gaccgaggag gccaaactgg cgtgtcaaac cttgcaggag ctggtctttc agctccgcat
    12301 cctctgtctg ctcatactgg tcaatgatac ggcggatgcg taagagagct gcccgcaggg
    12361 caaggttttc ctgcttaaag acatagacag ggtgtccttc ccggtccata tccgccacat
    12421 ccacatccgc aatggctcct ttgaagaggt tggcgtggat attgcagagg ctcatgacat
    12481 cttcaaaagt gatacccgta tcgctggaca tgagttcatg ctccatcatg gagatttcca
    12541 aggcagaaac tcccgtgaaa tgctgattaa actggtcctg aacagactct ggactggccc
    12601 cattgtgcag gtccaagaga atattcttca gaatgtcaac acgtttttcg gtcatgcttc
    12661 tcctcctatt acctcgtagc cgttgcattc caagacctgt tgaatacggt ctagtggaat
    12721 cttggtcatc ttagatcctg tcttcagact ggttacctta ccaactgtgt tcagcatagc
    12781 tggatttgcc aagggcttga aaccaagctc taccagaatg tccttgactt ctgggtgctg
    12841 gttgataatc tctgcaacag gcagatttag gtcgatggtg ttcattttac ttttcctcta
    12901 taattttttt gtaaaataca aggccaattc atcatcgtta taggctttgg cacctactgg
    12961 caaagagcac cctcggtacc agacaccgct tccgtctggt atgaaaccat gttttacata
    13021 gagccgttga gcctttccat aatttgcatt caaaccaact ccaataccta ctgtatccgt
    13081 aaattctgag gcaagttggc agatagcatc
//
LOCUS       DBNFCO010000055        12477 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.055, whole genome shotgun sequence.
ACCESSION   DBNFCO010000055 DBNFCO010000000
VERSION     DBNFCO010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 12477)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12477)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12477
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.055"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(403..1053)
                     /locus_tag="AC1PIV_001420"
     CDS             complement(403..1053)
                     /locus_tag="AC1PIV_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HIP6612438.1"
                     /translation="MYQTILFDLDGTLTDSGQGILNSVAYALEKMGIEEPDTANLNRF
                     IGPPLYESFSRFYQLSPEDTQSAVDAFRVYFKEKGMFENQLYPGIIPLLEELRTAGKT
                     LVIATSKPEIFAKQILEHFGISHYFDVIAGASLDSSRISKADVICYAINQLEAFPNHA
                     VMIGDREHDIEGARMHQLPAIGVLYGYGNKQEFEKAGATMIVETVQDLKRVLLTTE"
     gene            1161..2288
                     /locus_tag="AC1PIV_001421"
     CDS             1161..2288
                     /locus_tag="AC1PIV_001421"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HIP6612439.1"
                     /translation="MHILIAPDSFKESLSATKVAEAIKKGFSKVYPQAGYDLIPLGDG
                     GEGTVESLMQALSLDGTQTWVTGPFGDKIKVSYAVKDDLAVFEMAEIVGLASIPHERR
                     SPLFIKTQGVGELIVELVQNGVKRIFIGVGGSASHDGGIGMAAGLGVKFYNREGKEVE
                     AIGAHIGEIVSFSTEDMLVDLSQVRIDLVTDVENPLCGPAGATFVFAGQKGLTSAEFE
                     LVDKKMESFYKLVNPMLLDLAGAGAGGGMAAGLVQFAGARIRKGIDFVLDQLDFDHRV
                     TKAGLVVVGEGRMDAQSLSGKTPIGVARRTPTGIPIIAICGSLKDDLPEFPFENICAA
                     FPIIASVESLEDTLQKAEKNLVRTAEQVARILQLGGQQRWN"
     gene            2279..2449
                     /locus_tag="AC1PIV_001422"
     CDS             2279..2449
                     /locus_tag="AC1PIV_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612440.1"
                     /translation="MELVKYVAIILFIFICLAKLVSVMRLSEKERVTEMNVIKANGAM
                     FFFNEKMKEADC"
     gene            complement(2515..2967)
                     /locus_tag="AC1PIV_001423"
     CDS             complement(2515..2967)
                     /locus_tag="AC1PIV_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1694 domain-containing protein"
                     /protein_id="HIP6612441.1"
                     /translation="MNDLNTTILQKASGETRLNPDEQRLYMGTYRERVVLIVSFDDLS
                     SEVVGNKFDTICQKLANRYSPLFLKLSPALSDKQQISLLKIAQTFGITTAIIDEKIGQ
                     SPYALVFHTNHAVDNEEVSLESIFPNLISKPEEKKEDAKPSFWKKLFG"
     gene            3117..4424
                     /gene="eno"
                     /locus_tag="AC1PIV_001424"
     CDS             3117..4424
                     /gene="eno"
                     /locus_tag="AC1PIV_001424"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface-displayed alpha-enolase"
                     /protein_id="HIP6612442.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYLGLGTQKAVDNVNNVIADAIIGFDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYTYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPSFKEGLRWGAEVFHALKKILKARGLVTAVGDEGGFAPKFEGTEDG
                     VETIIEAIEAAGYEAGENGIMIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQI
                     DYLEELVNKYPIITIEDGMDENDWDGWKALTERLGKRVQLVGDDFFVTNTDYLARGIK
                     EGAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAG
                     QIKTGSLSRTDRIAKYNQLLRIEDQLGEVAVYKGLNSFYNLKK"
     gene            4734..4955
                     /gene="relB"
                     /locus_tag="AC1PIV_001425"
     CDS             4734..4955
                     /gene="relB"
                     /locus_tag="AC1PIV_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HIP6612443.1"
                     /translation="MSTVTIRLNQEEEVFFKSYAQLTGQSLSSLFKKALERDIEDEYD
                     LKIYHQAYDEYKADPETISHADFKKELGL"
     gene            4957..5217
                     /locus_tag="AC1PIV_001426"
     CDS             4957..5217
                     /locus_tag="AC1PIV_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0004521 - RNA endonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE family
                     toxin"
                     /protein_id="HIP6612444.1"
                     /translation="MYHLEYSKKAQKQIMKLDRQIQRLLFAWIDKHLEGTDNPRANGK
                     GLTGNHANEWRYRIGDYRLICDIQDDKLVILALEFGHRKDVY"
     gene            5384..6025
                     /locus_tag="AC1PIV_001427"
     CDS             5384..6025
                     /locus_tag="AC1PIV_001427"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HIP6612445.1"
                     /translation="MIEWIFFDLGSTLLDEEAAYGYYIDKCVKKLESLDIEVSSDSYK
                     KKMVEYAHKSLDPIRSTWHYFAPTEPRPLWTNEGVSLYPETIDALEKLSQNYRLGIIA
                     NQSSSIRELLKEWGIESYFQLIILSEEVGLSKPNTAIFTLALQKTNIPADRVVYVGDR
                     FDNDILPAKSLGMWTVRILTGFGKHASENEKLKSDWIIPSLQEITNIFEQTKN"
     gene            complement(6058..6243)
                     /locus_tag="AC1PIV_001428"
     CDS             complement(6058..6243)
                     /locus_tag="AC1PIV_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009910439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612446.1"
                     /translation="MNPVDLFNQVKELIANKDFDGAKQFIEENKDQFGEYLEQAKGLL
                     SGSEGVNGLLDKVKGLF"
     gene            complement(6307..7311)
                     /locus_tag="AC1PIV_001429"
     CDS             complement(6307..7311)
                     /locus_tag="AC1PIV_001429"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009910438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HIP6612447.1"
                     /translation="MAIYFGTYTKRESKGIYKANFDSETGQLSNLELVTEEPNPTYLA
                     FDKAGHLYSVGAENGLGGIAAFNTDYTLLNHVVSEGAPLCYVAVDEARDLVYGSNFHK
                     GQLLVYKRLADGSLELADVAQHEGSGPHENQASAHVHFSDLTPDKFLVTCDLGCDQVV
                     TYKVSDQGKVEKIATYQAAPGSGPRHIVFHTVAKIAYLICELNSTIEVLIYDGWGQFE
                     HLQTVSTLPEDHTGFNGTAAIRITKDGKFIYGSNRGNDSIAVYKTLADASLELVEIVP
                     TNGKTPRDFTLSPDEKHLIVVHQDSDNATVFKRDAENGCLTELSHDFYVPEAVCVTFL
                     "
     gene            7447..8613
                     /locus_tag="AC1PIV_001430"
     CDS             7447..8613
                     /locus_tag="AC1PIV_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HIP6612448.1"
                     /translation="MEDKHQKFSLTWFFRLFLNSQAVTFLLVTLLTFLTIFIFSKISF
                     LFRPIGSFLEIVLLPMILTGLLYYLLNPMVDWMEKHKISRTVGISILFVLISLLIIWG
                     LAVAIPSIQEQVTSFAQNLPSNIQKIEGQVTGLLQDQRFEQFRPTALEMLNKVNDQIV
                     AYAQKFSSSAVNWASNLISTASQIIVAILIMPFILFYLLRDGQYLNKHITQYLPTKWR
                     EPIGTVLSDVNGQLSNYVRGQVTVAIIVALMFSVMFSIIGLSYPITLGVMAGFLNLIP
                     YLGSFLAMIPAVILGLIAGPIMLIKVLVVFMIEQTIEGRFVTPLIIGSSLSIHPITIL
                     FVLLTAGQMYGVLGVLLGIPIYASIKVLVKAAFEWYKAHSGLYEDEENEVVNEQ"
     gene            8603..9832
                     /locus_tag="AC1PIV_001431"
     CDS             8603..9832
                     /locus_tag="AC1PIV_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HIP6612449.1"
                     /translation="MNNSEKMLVCLDQQDLDKADKYFKRALVQDDSETLLSLAAYLEG
                     IGFFPQARQIYEQVKEEFPEVLINLAQIAFEDGLVEESFGYLEEISEDSSVYVEALLV
                     KADLYQAEGLSDVAREKLLEASHLSDEPIILFGLAELDMELELFNEAISYYAQLDNRE
                     IYELTGVSTYQRIGIAYASLGKFEAAIEFLEKAVELEYDDQTVFELAALLFEREEYQK
                     ANLYFKQLDTINPDFEGYEYAYAQSLHVEHKIDDALVMTQKGLAKNDFDANLLLQASQ
                     YAYELHDEAGAEDYLLRAKEVADDSNELALRLSNLYLEQERFEEVVALFDEEVDNVLA
                     RWNVAKAYQALERDDEAIELYDELAGEFAENPEFLADYVAVLRQLGRLDEAKEQASRY
                     IQLVPDDLAMQEFLNEE"
     gene            9836..10552
                     /gene="budA"
                     /locus_tag="AC1PIV_001432"
     CDS             9836..10552
                     /gene="budA"
                     /locus_tag="AC1PIV_001432"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019322637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047605 - acetolactate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0045151 - acetoin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HIP6612450.1"
                     /translation="MQVNRLFQYNTLGALMAGLYGGSLTVGELLEHGDLGLGTLDSID
                     GELIVLDGKAYQAKGAGEKPEVVEVPAEMKVPYAAVIFHEAEVIFKQRFEMTSDELHQ
                     RIESYYDGENLFRSIKIKGTFSRMHVRMIPKSASDVRFAEVASRQPEYTAENISGTIV
                     GIWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDYVISEGMVEVGPVDQLDQRFPVQDR
                     QYLFAKFNAKEVREDIDKAE"
     gene            complement(10578..12236)
                     /locus_tag="AC1PIV_001433"
     CDS             complement(10578..12236)
                     /locus_tag="AC1PIV_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1990112 - RQC complex [Evidence IEA];
                     GO_function: GO:0001968 - fibronectin binding [Evidence
                     IEA];
                     GO_process: GO:0072344 - rescue of stalled ribosome
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein"
                     /protein_id="HIP6612451.1"
                     /translation="MSFDGFFLHHMTAELRANLEGGRIQKINQPFEQEIVLNIRSNRQ
                     SHKLLLSAHSVFGRVQLTQSDFTNPKVPNTFTMILRKYLQGAIIEEIRQLDNDRILEF
                     SVSNKDEIGDHIQATLIVEIMGKHSNIILVDKSEQKIIEAIKHVGFSQNSYRTILPGS
                     TYIRPPETHSLNPYTVSDEKLFEILSTQELSPKNLQQVFQGLGRDTASELANHLQIDR
                     LKNFRAFFDQATQPSLTDKSYAALPFANSPENQPHFESLSSLLDFYYQDKAERDRVAQ
                     QANELIKRVASELEKNRKKLIKQEQELADTETAELVRQKGELLTTYLHQVPNDQSSVR
                     LDNYYTGKELEIELDVALTPSQNAQRYFKKYQKLKEAVKHLTNLIEETKSTIVYLESV
                     DTMLGQASLAEIDEIREELIETGYLKRRHREKIHKRQKPERYLATDGKTIILVGKNNL
                     QNDELTFKMAKKGELWFHAKDIPGSHVVITDNLDPSDEVKTDAAELAAYFSKARHSNL
                     VQVDMIEAKKLHKPTGGKPGFVTYRGQKTLRVTPTEDKIKSMKI"
BASE COUNT         3524 a         2302 c         2844 g         3807 t
ORIGIN      
        1 tcaaaaaata ctagataagg tgtcattttg tcatgccctt ttatagctaa attagtgaca
       61 aaaataaggt agcagcctca aaatagctac tgttatgctt tatttttttg cttaaagcct
      121 tgatagactt gacaaatggt agaaaaagag ttcgtcaaca agtctttatt tctagttgtt
      181 gagctgaaac agtctatccc cagactgttt cactcccacc cccgcacagc tcaaactgtc
      241 tgggagacag tttgaggttg gaaatgaagc gaactctgtt cgcatcagtc atagaggtca
      301 gatttggagt gtaaaacacg aacaaatctg ccaatcaacc actgcgctga gatgttgaca
      361 cgaaccctga gaagcgaggt tggtcttttt gcccagcatc ttctattctg ttgtcagtaa
      421 aacccttttc aaatcttgga cggtttcgac tatcatggtg gccccagcct tttcaaattc
      481 ctgtttgttc ccatagccgt aaagaacacc gatggcggga agttggtgca tgcgtgctcc
      541 ttcaatgtca tgttccctat ctccaatcat cacagcatgg tttggaaatg cttctaattg
      601 atttatagca tagcagatga cgtccgcctt actgatgcga ctactatcca gactagcacc
      661 ggcaatgaca tcaaagtagt gtgagatacc aaaatgttct agaatctgtt tggcaaatat
      721 ttctggcttt gaggtagcaa ttactagtgt ttttccagcc gttctcaatt cttcaagcag
      781 agggatgatt ccaggataga gttgattttc aaacattcct ttttctttaa aatagacacg
      841 gaaagcatca actgcacttt gtgtatcttc agggctgagt tggtagaatc gagaaaaaga
      901 ttcatagagt ggcggaccga tgaatcggtt taaattggct gtatctggtt cttcgattcc
      961 cattttttct agtgcgtagg cgacggagtt taagattcct tgtccagaat cagtaagtgt
     1021 tccatctaag tcaaataata tagtttgata catacttatc tcctttcttt cagtataaca
     1081 cagacgatga aaaacagaaa agatttattg aaagctgact aggagcgtga tatactaata
     1141 atataaagga ggttagtacc atgcatattc tcattgctcc ggattcattt aaagagtctc
     1201 tttcagctac aaaggttgct gaagcgatta aaaaaggatt ttctaaagtt tacccacaag
     1261 cagggtatga cttaattccc ctaggagatg gtggcgaagg gacagttgag agtctaatgc
     1321 aagccttatc cttggatgga acccagactt gggtgacagg tccatttgga gataaaatta
     1381 aggtttccta tgcggttaaa gatgatcttg cggtttttga aatggctgag attgtagggc
     1441 tggcaagtat cccgcatgaa agaaggagtc ctctctttat taagacacaa ggggttgggg
     1501 agctgattgt ggagctcgtt caaaatggtg ttaaacgcat atttatagga gtaggtggct
     1561 ctgccagtca tgatggtggt atcggaatgg cggcaggttt aggagtgaaa ttttataatc
     1621 gagagggaaa agaagtagag gcaattggag ctcatatcgg ggagattgtc agcttttcca
     1681 cagaggatat gttggtagat ctatctcagg tcaggattga tttggtaacg gatgtggaga
     1741 atccgctttg cggaccagcg ggtgccacat ttgtttttgc aggtcagaaa ggtcttacct
     1801 ctgctgaatt tgaactagta gacaagaaaa tggagtcctt ttataaatta gttaatccaa
     1861 tgctactcga tttggcagga gcgggtgctg gaggaggtat ggcagcaggt ttagtccaat
     1921 ttgctggtgc tcgcattcga aaaggcatcg actttgtctt ggatcagttg gactttgatc
     1981 atcgcgtcac caaagcgggt ctggttgtgg tcggagaagg gcggatggat gcccaaagct
     2041 tatcagggaa gactccaata ggagtagcta gacggacgcc gacggggatt cccatcattg
     2101 caatttgtgg tagcctcaaa gacgatcttc ccgagtttcc ttttgaaaat atctgcgccg
     2161 cttttccgat aattgcaagc gttgaaagtt tggaggacac gcttcaaaaa gcagaaaaaa
     2221 acctggtccg cacggcagag caggtggcaa gaattcttca gttaggaggc caacaaagat
     2281 ggaattagtg aaatatgtgg ctattatctt atttattttt atttgtcttg caaagctagt
     2341 atccgttatg agactttccg aaaaagaaag agtaacggaa atgaatgtaa taaaggcaaa
     2401 cggagcaatg ttctttttca atgaaaaaat gaaagaggca gattgctagg aatcctttgt
     2461 ctaacctgta ttatttttac tttaatattt atactgcttt atcgttaaat aagtctaacc
     2521 aaataatttt ttccagaagg aaggttttgc atcttccttt ttttcttctg gttttgagat
     2581 aagatttgga aatatggatt ctaagctaac ttcttcatta tccacagcgt gatttgtgtg
     2641 aaagacaagt gcgtagggag attgtcctat tttttcatcg atgatagcgg tagtaatgcc
     2701 aaaggtctga gcaattttta gtagtgaaat ttgttgcttg tcagacaggg ctggcgagag
     2761 tttgaggaat agaggagagt atctgtttgc tagtttttgg caaattgtat cgaacttatt
     2821 tccgacgact tcactactca aatcgtcaaa ggaaacgatc aggacaaccc gttcgcgata
     2881 ggttcccatg tatagacgct gttcatctgg attcaatcgt gtttcgccag aggctttctg
     2941 tagtatggta gtatttaaat cgttcatggt ttcagtataa catactcagt taactttgaa
     3001 aaggaaggcg tttacattat ttctttcagt aaaataacct gttttttctt gaaaaatccc
     3061 ttcttttagg gtatgatagc tatgtaacaa ttttaaactc aaaggagagt aatataatgt
     3121 caattattac tgatgtttac gctcgcgaag tccttgactc acgcggtaac cctacacttg
     3181 aagttgaagt ttatactgaa tcaggtgctt tcggacgtgg tatggttcct tcaggagctt
     3241 ctactggtga gcacgaagca gttgagcttc gcgacggtga caaatctcgt taccttggtc
     3301 ttggtactca aaaagctgtt gacaacgtga acaacgtgat tgctgacgct atcatcggtt
     3361 ttgacgttcg tgatcaacaa gctatcgacc gcgctatgat cgctcttgac ggtactccta
     3421 acaaaggtaa attgggtgca aacgcaatcc tcggtgtttc tatcgctgtt gcgcgtgctg
     3481 ctgctgacta ccttgaagtg ccactttaca cttaccttgg tggattcaac actaaagtat
     3541 tgccaactcc aatgatgaac atcatcaacg gtggttctca ctcagacgct ccaatcgctt
     3601 tccaagaatt catgatcttg ccagttggcg ctccttcatt caaagaaggt cttcgttggg
     3661 gtgctgaagt attccacgct ttgaagaaaa tcttgaaagc tcgtggtttg gtaacagctg
     3721 ttggtgacga aggtggtttc gctcctaagt tcgaaggaac tgaagacggt gttgaaacaa
     3781 tcatcgaagc tatcgaagct gctggttacg aagctggtga aaacggcatc atgattggtt
     3841 tcgactgtgc gtcatctgaa ttctacgaca aagaacgtaa agtttacgac tacactaaat
     3901 tcgaaggtga aggcgctgct gttcgtacat ctgcagaaca aatcgactac cttgaagaat
     3961 tggttaacaa atacccaatc atcactatcg aagatggtat ggatgaaaac gactgggatg
     4021 gctggaaagc tcttactgag cgtcttggca aacgcgttca attggttggt gacgacttct
     4081 tcgtaacaaa cactgactac cttgcacgtg gtatcaaaga aggtgctgct aactcaatcc
     4141 ttatcaaagt taaccaaatc ggtactctta ctgaaacatt tgaagctatc gaaatggcta
     4201 aagaagctgg ctacactgcc gttgtatcac accgttcagg tgaaactgaa gattcaacaa
     4261 tcgctgacat cgcagttgca actaacgctg gccaaatcaa gactggttca ttgtcacgta
     4321 cagaccgtat cgctaaatac aaccaattgc ttcgtatcga agatcaactt ggtgaagttg
     4381 cagtctacaa aggcttgaac tcattctaca acttgaaaaa ataaaacagt ctgggagact
     4441 gttttatccc tgagctagca tagcgagggt tatagtaaga acaagtctgg aaatttccag
     4501 acttgttttt cgtagtacag tgtactaatt tatccccgag ctagtatagt gagggatata
     4561 gtaagaacaa gtctgaaaat attcggactt gttctttgac tttatatgat ttaagggctg
     4621 taaagccttg atataaggca ctttggggca tcatcccaag gtactttttt gatagattga
     4681 cagatacttt aaaaatgtgt tacaatgtaa cacaaagaag cgaggtgaat atcatgagta
     4741 cagtgacaat cagattaaat caagaagaag aagtattctt taaaagctat gcacaattaa
     4801 caggtcaaag tctttctagc ctttttaaga aagctttgga gcgtgatatt gaagatgagt
     4861 atgatttaaa aatctatcat caagcttatg atgagtacaa agcagatcca gaaacaatta
     4921 gtcatgctga ttttaagaaa gagctaggat tatagcatgt atcatttaga gtattctaaa
     4981 aaggctcaaa agcaaattat gaaattagat aggcaaattc agaggctgtt gtttgcttgg
     5041 attgataaac acttagaagg gactgataat ccacgcgcca atggtaaagg tttgacaggc
     5101 aatcatgcta acgagtggcg ttatcgtatc ggagattacc gactgatttg cgatattcaa
     5161 gatgataagt tggttatttt agcacttgag tttggacatc gtaaagatgt ctattgatgc
     5221 gtgaaaatct atgacaagat aggtcctaac tatttttaag aatgaataga aaactagact
     5281 gaaattccta gggaattttc tttgccttga tattgataaa atgatattct aaaaaggcag
     5341 atcaacttaa gtattctcat tttgaaaaga gatggagagt gggatgatag agtggatatt
     5401 ttttgatttg ggttcgacgc ttttagatga agaggctgct tatggttatt atatagacaa
     5461 gtgtgtgaag aagttagagt ctctggatat agaggtttca tcagattctt ataaaaagaa
     5521 aatggtggag tatgctcata agtcgctgga tcccattcgt tcgacctggc actattttgc
     5581 accgaccgag ccacgtcctt tgtggacaaa tgagggtgtg agcttgtatc ctgaaacaat
     5641 agatgctcta gagaagttat cacaaaacta tcgattgggg attattgcca atcagtctag
     5701 tagtattaga gaactgctta aagagtgggg aattgagtct tattttcaac tcatcatcct
     5761 ctctgaagag gttgggctat ctaaaccaaa tacagctatt ttcacacttg ccttgcaaaa
     5821 aacaaacatc cctgcagata gagttgtcta tgtcggggat aggtttgata atgatattct
     5881 gcctgctaaa tctttgggaa tgtggactgt acggatactg acaggttttg ggaagcatgc
     5941 cagtgaaaat gaaaaattga agagcgattg gataattcct tcattgcaag agataacaaa
     6001 tatttttgaa caaacaaaaa actagactga acattctcag cctagttttt acatgtatta
     6061 gaacaagcct ttaactttat ctaaaagacc gttaacacct tcagaacctg ataacaagcc
     6121 ttttgcttgt tccaagtatt caccgaattg gtccttgttt tcttcgataa attgttttgc
     6181 accatcaaag tctttgtttg caatcaattc ttttacttgg ttaaaaagat ctactggatt
     6241 catgttgaaa tcacctccta tgagactatt aaaccaaaac tgtacggatt tcacaactga
     6301 aacgacttat aaaaatgtaa cgcaaactgc ttcaggaaca tagaaatcgt gtgaaagctc
     6361 agtcaaacag ccattttcgg catctctttt gaatacagtt gcattgtcag aatcttgatg
     6421 gacaacaatc aaatgctttt catcaggact aagcgtgaaa tcgcgaggag tttttccatt
     6481 tgttgggacg atttcaacta attctaagct ggcatcagca agcgttttgt agactgcgat
     6541 agagtcgttt ccgcggttgg atccataaat aaatttacca tcctttgtga tgcgaatagc
     6601 ggcagtaccg ttgaaaccag tatggtcttc tgggagagta gagacagttt gtaggtgttc
     6661 aaattgtccc cagccgtcgt agataagcac ctcaatagtt gaattgagtt cacagatgag
     6721 ataggcgatt tttgcgacag tatggaagac aatgtgacgt ggaccacttc ctggcgcagc
     6781 ctgataggtt gctattttct ctacttttcc ttggtcagat accttatagg ttaccacttg
     6841 atcacatcct aaatcacagg ttactaaaaa tttatcgggc gtcaaatcag aaaagtgaac
     6901 gtgggcggaa gcttggtttt cgtgcggccc agatccttcg tgttgagcga catcagctaa
     6961 ttctagcgaa ccatccgcca aacgtttata aacaagtagt tgccctttgt ggaaattgga
     7021 accataaact aaatctcttg cttcatctac agcgacatag caaagtggtg cgccctctga
     7081 tacaacatgg ttgagtagag tatagtcagt attaaaggca gcgatacctc ctagaccatt
     7141 ttcagcgccg acggagtata gatgtccggc cttatcaaag gcaaggtagg tagggttagg
     7201 ttcttcagtg accaattcta gattgctaag ttgtcctgtt tcagagtcaa aatttgcttt
     7261 ataaattcct tttgattcac gttttgtata ggtaccgaaa tagatagcca taggattctc
     7321 ctttttggaa atgattgata aaattatacc atgtttttct gagaaagtcg tatagattct
     7381 gtagttgatt tttacaaaaa tcctttctcc atgttacaat agaaaaaaag actaggagtg
     7441 tatcagatgg aggataagca tcaaaaattt agtctgactt ggtttttccg cttgttttta
     7501 aatagccaag cggtgacatt tttattggta accttgctga cttttttgac catatttatt
     7561 tttagtaaaa ttagtttttt attcagacca ataggaagct ttttagaaat tgtattgtta
     7621 ccgatgattt taacaggtct tttgtattac ctattaaatc cgatggttga ctggatggaa
     7681 aagcataaaa tttctcgtac agttggtatt tccattctct ttgttttaat cagtcttctc
     7741 attatctggg gactggcggt ggcaattccg agtattcaag agcaagtgac atcttttgcg
     7801 caaaatcttc cttcgaatat ccagaaaatc gaaggacagg taactgggct cctacaggat
     7861 cagcgctttg aacaatttag accaacagct ctggagatgt taaataaggt caatgatcag
     7921 atcgttgcct atgctcagaa gttttcttca agcgctgtga actgggcaag taatttgatt
     7981 tcaaccgctt cacagattat tgttgctatt ttgattatgc cctttattct cttttatcta
     8041 ttacgggatg gtcagtattt gaataaacac atcacccaat atctaccaac caagtggaga
     8101 gaaccgattg gaacagtact atcagatgtg aatgggcaat tatcaaacta tgttcgtggt
     8161 caggtgaccg ttgcgattat tgttgccctg atgttttcag tgatgttctc aatcattggt
     8221 cttagctatc caataacttt gggggtgatg gctggtttcc tcaatctaat tccgtatttg
     8281 ggttctttct tggccatgat tccagctgtt attttaggat tgattgctgg tccaatcatg
     8341 ctgataaagg ttttagtagt ctttatgatt gagcaaacta tagaaggtcg ttttgtgaca
     8401 ccattgatta tcggaagctc cctaagtatt catccgatta ccattttgtt tgtattattg
     8461 acagctggtc agatgtatgg tgtcctagga gttcttctgg gaattccaat atatgcctct
     8521 attaaggttt tagtgaaagc ggcatttgaa tggtacaagg cacacagtgg tttgtatgaa
     8581 gatgaagaaa atgaggttgt gaatgaacaa tagtgaaaaa atgttggttt gtttggacca
     8641 acaggattta gacaaggcag ataagtattt caagcgcgcc ttggtgcaag atgatagcga
     8701 aacgcttttg tccttggcag cctacttaga aggcattggt tttttcccac aggctagaca
     8761 aatctatgag caggtcaaag aagaatttcc cgaagtactg atcaatcttg cccaaatagc
     8821 atttgaagat ggcttggttg aagaatcttt tggatacttg gaggaaattt cggaagacag
     8881 ttctgtctat gtggaagcct tgttggttaa ggcggacctg tatcaggcag aaggcttgtc
     8941 ggatgtggcg cgtgaaaaat tgttagaagc aagtcactta tcagatgaac ccatcatcct
     9001 ctttggctta gcagaattgg atatggaact ggagcttttt aatgaggcta tttcctacta
     9061 tgcccagctg gataatcgtg agatctacga attaacggga gtttctacct atcagcgaat
     9121 tggtattgcc tatgcaagtt tggggaaatt tgaagcggcg attgaatttt tggaaaaagc
     9181 tgttgagttg gaatacgatg atcagacggt ttttgagtta gcagctctgc tatttgaacg
     9241 agaagaatac caaaaagcaa atctctattt caagcagttg gataccatca atcctgattt
     9301 tgagggctat gaatatgcct atgctcagtc gcttcatgtc gagcataaga ttgatgatgc
     9361 cttggttatg actcaaaaag gcctggctaa aaatgatttt gacgccaatc tcttgctcca
     9421 ggcttctcag tatgcctatg aattgcatga tgaggcgggg gcagaagatt atcttctacg
     9481 ggcaaaagag gtagcagatg atagtaacga actagctctg cgcttgtcca atctgtatct
     9541 tgagcaggaa cgatttgaag aggttgtggc tttatttgat gaagaggtag ataacgttct
     9601 agctcgctgg aatgtggcca aggcttatca agctctagaa agagacgatg aagctattga
     9661 gctttacgat gaattggctg gagaatttgc tgagaatcct gaatttttgg ctgattacgt
     9721 agcggtttta cgtcaacttg gtcgtttgga tgaggcaaaa gagcaagcta gtcgttatat
     9781 ccaattggtg ccagacgatt tagccatgca agaatttttg aatgaagagt aggttatgca
     9841 agtaaatcga ttatttcaat acaatacctt aggtgcctta atggctggac tgtatggcgg
     9901 ctccttgacg gttggcgaat tgttggaaca tggtgatttg ggcttgggaa ccctggattc
     9961 cattgatggc gagctgattg tcttggatgg aaaggcttat caggccaagg gagcagggga
    10021 gaaaccagaa gtggttgaag ttcctgctga gatgaaggtt ccttatgcag cggtcatttt
    10081 ccatgaagca gaagtgattt ttaagcaacg ctttgaaatg accagcgatg aattgcatca
    10141 gcggattgaa tcctattatg atggggaaaa tctttttcgc tccatcaaaa tcaaagggac
    10201 gttttcacgg atgcatgtcc gcatgattcc aaaatcggct tctgatgttc gttttgcgga
    10261 ggtggcaagt cgtcagcctg agtataccgc tgagaatatt tcaggtacca ttgttggtat
    10321 ttggacacca gaaatttttc acggggtcag tgtggctggc tatcatttgc attttatttc
    10381 ggatgatttg acatttggcg ggcatgtcat ggattatgtt atctcagaag gaatggtgga
    10441 agtggggcca gtagatcaac tagaccaacg cttcccagtc caagaccgcc aatatctttt
    10501 tgctaagttc aatgctaagg aagttagaga agatattgat aaggcggagt aggcttcaat
    10561 acagaaaaat ccatgaacta gattttcatg gattttattt tatcttcagt tggggtgaca
    10621 cggagggtct tctgacctcg gtaggtcaca aagcctggtt tgccacctgt tggcttatgg
    10681 agttttttgg cttcaatcat gtcgacttgg accagattgg aatgtctggc cttggagaag
    10741 taggcagcta attcagctgc gtctgtcttg acctcgtcac ttgggtccaa gttatctgtg
    10801 atgaccacat gactaccagg aatgtctttg gcatggaacc agagttcgcc ttttttggcc
    10861 attttgaagg tcaactcatc attttgcagg ttattttttc ctaccagaat gatggttttc
    10921 ccgtctgttg ccaagtaacg ttcaggtttc tgacgcttat ggattttctc acgatgacgg
    10981 cgtttgaggt agcctgtttc aatcaattcc tcacggattt catcgatttc tgccagacta
    11041 gcctgtccca gcatggtgtc aacggactcc agatagacaa tggtcgactt ggtctcctca
    11101 atcaagttgg tcaggtgctt gaccgcctcc ttgagtttct ggtacttctt gaagtaccgc
    11161 tgggcatttt ggctaggagt caaagccaca tccaactcaa tctccagttc cttgcccgta
    11221 tagtagttgt ctaaccgcac actcgactgg tcatttggca cttgatgcag ataggtggtc
    11281 aggagctcgc ccttttgccg caccaactcc gccgtctccg tatccgccaa ttcctgctcc
    11341 tgcttgatta gtttcttgcg atttttctcc aactcactgg ctacccgctt gatcagctca
    11401 ttggcctgct gggccacccg atcccgctcc gccttatcct gatagtagaa gtccagcaga
    11461 ctgctcaggc tctcaaagtg tggctggttt tcagggctat tggcaaatgg cagagcagca
    11521 taggatttgt ctgtcaggct aggctgagtt gcctggtcaa aaaaggcacg gaagttcttc
    11581 aggcggtcta tctgcaaatg attggccagt tcagaagccg tatcccgacc caaaccttga
    11641 aagacctgtt ggagattttt tggactcagt tcctgagtcg ataagatttc aaacaatttc
    11701 tcgtcagaca ccgtataagg attgagagaa tgcgtctccg gtggacgaat ataggtggag
    11761 cctggcaaga tggttcggta ggaattttgc gagaaaccaa cgtgcttgat agcctcaata
    11821 atcttctgtt cagacttatc taccaagatg atattgctgt gcttgcccat gatttccaca
    11881 atcaaggttg cttggatatg gtcgccaatc tcgtccttgt tggacaccga aaattctaag
    11941 atacggtcat tgtccaactg acgaatctcc tcgataatgg ctccctgcaa gtatttccgc
    12001 agaatcatgg taaaggtatt gggcactttt ggattggtaa agtccgactg ggtcagctga
    12061 acccgaccga aaaccgaatg ggcggacaga agcaatttat ggctctgacg gttgctgcgg
    12121 atgttgagga caatctcttg ttcaaagggc tggttgattt tctgaatccg cccaccttct
    12181 aaattggccc ttaactcagc cgtcatgtga tgtaaaaaaa atccgtcaaa agacatagtt
    12241 ttcctctttc taatagctat aactcagtct agtatatcat aaatcagtga ctttttaacg
    12301 aaggggacta aaagaagtat tcttatattt ttataaatta ttgacaaatt ctttaattta
    12361 tattaaaatt gaaaatggtt acagagttat taaatttttt aagctagaag taccaactaa
    12421 taattgaaat aaaaggatgt tatcgcttta aggcgagcag gaacctattt aaatgaa
//
LOCUS       DBNFCO010000056        11663 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.056, whole genome shotgun sequence.
ACCESSION   DBNFCO010000056 DBNFCO010000000
VERSION     DBNFCO010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 11663)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11663)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11663
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.056"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            <1..707
                     /locus_tag="AC1PIV_001434"
     CDS             <1..707
                     /locus_tag="AC1PIV_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HIP6612452.1"
                     /translation="LQSGGIKLTTYIEDIMGLSGRNLLQLLVDGTPITPRIVHQSVYT
                     SLKKKVPQLLEALDGYFSDHHRFMLKQSLEIYDFYQKQIELLEERITVYLSQYENHVE
                     TLDSIPGIDVITASVIISEVGVDMSQFPTSGHLASWAGLCPGNNESAGKKRSTKIRHG
                     NSYLKKCLCQAAFAARNQKGSTLADRFYQIQSRRGSQKATIALAHQLLKIAYILLKEQ
                     MTYPEFLAQKRLLGTS"
     gene            complement(1245..2183)
                     /locus_tag="AC1PIV_001435"
     CDS             complement(1245..2183)
                     /locus_tag="AC1PIV_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /protein_id="HIP6612453.1"
                     /translation="MLDQIKAHLLDSINDIVSTANQFLLHPKKDFSRKSQLTRNLDER
                     AAFIDMLKTSSFKQALVIMDRGYESYNVMVHCQERNWSYIIRIRVGNHSMKSGFNLPD
                     TPCFDEAFDLNICRKQTNEMKQLYRDFPNHYRCLPNHTSFDFLPNSSRKRDPLQFYDL
                     HFRMVRLEIKPGFFETLVTNTDYSPEKLKDLYAYRWGIETSFRDLKYSIGLTHFHAKK
                     KEGILQEIYARFINFNVCKWLTSHVTIKTSKLKQTYKICFSDAVYACRKFLREELTSF
                     QLETYIAKHLSIIRPNRTFQRKIKSQAPVSFTYRIS"
     gene            2323..3543
                     /locus_tag="AC1PIV_001436"
     CDS             2323..3543
                     /locus_tag="AC1PIV_001436"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HIP6612454.1"
                     /translation="MLENWLNTKQGQVFHYKMEKIEYALELLGNPQFAVPVIHVAGTN
                     GKGSTIAFMRKLFQAHGMRVGSFVSPHMVSVHDRICIDSQPISDHDFQHYLQKVYDLE
                     QEIATRYEPFRYFEVMVLIMFLYFEAQQPDVALVEVGIGGLLDTTNVVAPALSVITSI
                     GMDHQDLLGSTLREIAEQKAGIIKESVPVVLGPLSPETTAICRQIAQDNQAPVYQFGQ
                     EFTYKAGQFSNPDIDLSELVLGLAGHHQEENAAVALQTFLLYMTNIQKDIQPQLIQQA
                     LAQTSWPGRLELVVQEPKIYLDGAHNVPAIERLLEFIQVQEEPVTILFSALRRKDFQE
                     MLELLEEKLPHTPLVLTSFAYDGALAEENRQGRDYVENYQQFIEDWQSSKQGILIVTG
                     SLYFISEVRRIFKK"
     gene            3734..5257
                     /locus_tag="AC1PIV_001437"
     CDS             3734..5257
                     /locus_tag="AC1PIV_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinol oxidase"
                     /protein_id="HIP6612455.1"
                     /translation="MTELDVVSDVVTHPEETYRRSRRASRRQQVQLNGEFHERVLKTK
                     YWPALVWSLVLSVFSVANPLLMPFATNIQTQNLYAGMAMANGQIPYGDFFGTSGLLFY
                     LLAFLGHLGGTFIIFGILQFIALLIAGVYFYKIVAYFSQSEHLAISSSHWFYVFIFAL
                     GFGGMYAEMFALPFLLTSVWFLVRYFENAVRDEAFILYGIDAALVFLIYPKSLILWLV
                     AGLVLFIFNIQHRQVTRGIYQLLATIFGFLLILYAVGYYAFEAQILGTAIQQTFLYNL
                     QLDFHHSYLYLALAIVSVFLLLSGFFKSFIQMVFSFKQGRHTYIKVLLLLTFLVQCVF
                     IIGNANFQWSQLILLLPYGFAMSVVYLRDEDVEDYSGYLRRQFFLPLAICLGIIAQPV
                     YLYLVQGDLRTDREQVANYIDEQTKDSDKIYVWDNSASIYLSSQRLSAATITTAEPYL
                     NTDDNKNSLMYDINKNEAKFVVVNKNLPILDEIKTNLESQYQSVQTTDYFTIYQKNE"
     gene            5375..7312
                     /gene="mutL"
                     /locus_tag="AC1PIV_001438"
     CDS             5375..7312
                     /gene="mutL"
                     /locus_tag="AC1PIV_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0032300 - mismatch repair complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HIP6612456.1"
                     /translation="MSHIIELPEILANQIAAGEVIERPASVVKELVENSIDAGASQIE
                     ISVEEAGLKMIQITDNGEGIAPDEVALALRRHATSKIKNQSDLFRIRTLGFRGEALPS
                     IASVSHMIIETATADSAHGLHLEAKGGVIEKEEPVSRPVGTQITVSDLFYNTPARLKY
                     VRSQQAELSHIVDVVNRLSLAHPEIAFVLVNEGRELIRTAGTGKLRQAISGIYGIASA
                     KKMVEIEAEDLDFQISGYVSLPELTRANRNYISIFINGRYIKNFLLNRAILEGYGSKL
                     MVGRFPLAVISIEIDPYLADVNVHPTKQEVRISKEKELMTLIREAISQALKEQDLIPD
                     ALENLAQSSTRPKVKAEQGTLPLREPKIYYDTIKQDFFLKPDVVAEDVKPLEEDRQEI
                     VESPVENRPTSVQFAERQSVESEDQEHPNLSAKELAKLADKLDREETSTFPELEYFGQ
                     MHGTYLFAQGKTGLYIIDQHAAQERVKYEYYREKIGQVDNSAQQLLVPYIFEFPQNDA
                     LDLVHKMDALRQVGVNLEEYGSNQFILREHPIWMKEEEIESGIYEMCDMLLLTDQVSI
                     KQYRAELAIMMSCKRSIKANHALDDYSARDLLRQLSYCQNPYNCPHGRPVLVHFSKSD
                     MEKMFRRIQENHTSLRELGKY"
     gene            7351..7941
                     /gene="ruvA"
                     /locus_tag="AC1PIV_001439"
     CDS             7351..7941
                     /gene="ruvA"
                     /locus_tag="AC1PIV_001439"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HIP6612457.1"
                     /translation="MYDYIKGILTKITAKYIVVETQGVGYILQVANPYAYSGQVQQEV
                     TVYTHQVIREDAHLLYGFATENEKSVFLSLISVSGIGPTTALAIIAVDDNDGLVRAIE
                     QKNITYLTKFPKIGKKTAQQMILDLEGKFVMSEEAGPVQQVAPSSENIALEEAMEAME
                     ALGYRPAELKKIKKFFEGTNDTAENYIKSALKMLMK"
     gene            8666..9235
                     /locus_tag="AC1PIV_001440"
     CDS             8666..9235
                     /locus_tag="AC1PIV_001440"
                     /EC_number="3.2.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012774893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008725 - DNA-3-methyladenine glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HIP6612458.1"
                     /translation="MSRCAWVNPNNPLYIAYHDEEWGKPLHDEQSLFELLCLESYQAG
                     LSWEIVLNKRQAFRSAFFNYDIQKVAAMTDSELDSLLTNPDIIRHKAKLYATRANAQA
                     FLRVQEEFGTFDTYLWEWVNFTSIDNPVKSFRELPTKNDLSERISKDLKKRGFKFVGP
                     VCIYSYLQAAGLLNEHEETCEIGKKLRTN"
     gene            9272..10453
                     /locus_tag="AC1PIV_001441"
     CDS             9272..10453
                     /locus_tag="AC1PIV_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HIP6612459.1"
                     /translation="MKAELIAVGTEILTGQIINTNAQFLSEKCAELGIDVYFHTAVGD
                     NEGRLLSTLEVASKRSNMVVLCGGLGPTEDDLTKQTLATFLGRNLVFDELAMAKLDRF
                     FASRPGRVRTPNNERQAQIVEGSQALQNPAGLAVGGMIEQDGVTYIVLPGPPSELKAM
                     FSESLLPLLSQSQQQLYSRVLRFFGIGESQLVTVLADVIDKQTDPTLAPYAKVGEVTL
                     RLSTKATSQEEANLRLNQLEEDILQHDKLADYFYAYGEDNSLVKTVATRLAEKRQTIA
                     IVEQGTGGLLQAELSLALADQPYFSGGKVVGQLGIESGWLSEEADCIRQELQADLGLA
                     VSVLIKPESTEDNVLAKVYLTLATPSGISQKEIDLGGYSWQYLRQLACLQAWDFVRNT
                     L"
     gene            10505..11656
                     /gene="recA"
                     /locus_tag="AC1PIV_001442"
     CDS             10505..11656
                     /gene="recA"
                     /locus_tag="AC1PIV_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001085741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HIP6612460.1"
                     /translation="MAKKPGKKLEDITKKFGDERKKALDDALKSIEKDFGKGAVMRLG
                     ERAEQKVQVMSSGSLSIDIALGAGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKDGG
                     IAAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSV
                     AALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTVAIFINQLREKVGVMFG
                     NPETTPGGRALKFYASVRMDVRGNTQIKGTGDKKDQNVGKETKVKIVKNKVAPPFKEA
                     VVEIMYGEGISCTGELIEIGSNLGIIQKAGAWYSYNGEKIGQGSENAKKFLADNPAIF
                     DEIDRKIRVHYGLIEADGVEEVATEEAPVVAEEIQDVILDLDGGIELED"
BASE COUNT         3422 a         2239 c         2620 g         3382 t
ORIGIN      
        1 ttcttcagtc aggtggtatc aagctaacaa cctatattga agatattatg gggctatctg
       61 gtcgcaatct ccttcagcta ctggttgatg ggacgcctat tacacctcgc attgttcatc
      121 aatccgttta taccagcttg aagaagaaag tgccgcagct tctggaagcc ttggacggtt
      181 atttctctga ccatcatcgc tttatgttaa agcagtcctt agagatttat gatttttatc
      241 agaagcagat tgagttgttg gaagagcgaa ttactgtcta tctatcacaa tatgaaaacc
      301 atgtagaaac attggattcc atcccaggca ttgatgtcat tacagcttct gttatcattt
      361 ctgaggttgg tgttgacatg agtcagtttc cgacatctgg acatttagct tcttgggctg
      421 gactctgtcc aggtaataat gagagtgctg gtaaaaaacg aagtaccaag attcgacacg
      481 gaaattcata tttgaagaaa tgtttatgtc aagccgcttt cgccgctagg aaccagaaag
      541 gaagtaccct agcagaccga ttttatcaga ttcaaagtcg gcgtggctca caaaaagcaa
      601 ccattgcact tgcgcatcaa ctattaaaaa tagcctatat ccttttaaaa gaacagatga
      661 cttatcctga atttttagca caaaaaagac tactagggac gagctagtag cctaatataa
      721 aaattgtttc actttgattc tatcataggg agggagtttc tgcattcttt tgagttttcg
      781 tataagaact cgactggtca aaaagagttc gtcaacaagt ctttatttct agttgttgag
      841 ctgaaacagt ctattcccag acatcaattt atgtgagctg actgccgtca gcttatatct
      901 cccactttaa aaggtctccc agacctttta aactcccacc cccgtatagc tccaacagtc
      961 agagtagtga ctgttggagg ttggagataa ggcgaactct gttcgcatca gtcgtaatgg
     1021 tcagatttgg agtgtaaaac acgaacaaat ctaccaatca accactgcgc tgagatgttg
     1081 acacgaattc tgagaagtgt gctggcttga gcccaatgtc attaagttaa gcatttaaac
     1141 aattaaagaa actattcccg tctgagcagt tgatgacaag acgggaatag tttttgtatt
     1201 tagggcacac aaaaaggaag gtttttaacc caatttttta actattatga tattctataa
     1261 gtgaagctta cgggagcctg gctttttatc tttctttgga aggttcgatt gggtcggatg
     1321 atggataaat gtttggcaat gtaggtttct aattggaagg aagtaagttc ttctctaaga
     1381 aattttcgac aggcataaac agcgtctgaa aaacaaattt tataagtctg ttttaacttt
     1441 gatgttttaa tggtaacgtg tgaggttagc catttacaaa cattaaagtt gataaagcga
     1501 gcgtagattt cttgcagaat cccttccttc tttttcgcat gaaaatgagt caacccaata
     1561 ctgtatttta ggtcacgaaa actggtctct atgccccatc tgtaggcata gagatctttt
     1621 aatttttctg gtgaataatc cgtatttgtc accaaagtct caaagaaacc tggcttgatt
     1681 tcgagacgca ccatccgaaa atgaaggtca taaaactgga gtggatccct ttttcggcta
     1741 gagtttggta aaaagtcaaa ggatgtgtga ttaggtaaac agcgatagtg attaggaaag
     1801 tctcgataca gttgtttcat ctcattggtt tgttttcgac agatgtttag gtcaaatgcc
     1861 tcatcaaaac aaggggtgtc agggaggtta aatcctgact tcatagaatg attcccgaca
     1921 cgaatacgaa taatatagga ccaatttctt tcttgacagt gtaccatgac attgtaggat
     1981 tcataccccc tatccattat caccagagct tgtttgaaag aagaggtctt cagcatgtca
     2041 ataaaagctg ctcgttcatc aagattccta gttagctgac ttttccgact aaaatctttt
     2101 ttaggatgaa gtaaaaactg gtttgcggtg gaaacgatgt cgttaatact atcaagtaaa
     2161 tgagctttaa tctgatctag catgactttt ccccttttat ttttagtgta ctatagaaaa
     2221 aactaaccta ccacaaaacg tgataggtta gttaacttaa tgacattggg ctttttgccc
     2281 agcctctttt ttgttatact agacagtatg taggaggtgg ctatgttaga aaattggtta
     2341 aacaccaaac aaggtcaggt gtttcattac aagatggaaa agattgagta tgccctagaa
     2401 ctgctaggga atccccagtt tgcagttccg gtcattcatg tcgctggaac taatggcaag
     2461 ggatcgacca ttgcctttat gcgcaagcta tttcaggcac atggtatgcg tgttggaagt
     2521 tttgtatccc cccacatggt gagtgtacac gacaggattt gtattgacag ccagcccatt
     2581 tcagaccatg attttcagca ctatttacag aaagtctacg atttggagca ggaaatcgcc
     2641 actcgttatg agccttttcg ctattttgag gtcatggtgc tcattatgtt cctctatttc
     2701 gaagctcaac aacccgatgt ggcactagta gaggtgggca tcggaggact tttggatacg
     2761 accaatgtcg tggccccagc cctaagcgtt atcacctcca tcggcatgga ccatcaggat
     2821 ttattaggct cgactttaag ggaaatagca gagcagaaag cagggattat caaggaaagc
     2881 gtacctgtcg tcctaggacc gctttctcca gaaaccacag ccatctgtcg ccaaattgcc
     2941 caagacaatc aagcacctgt ctaccaattt ggtcaggaat tcacctataa agcaggacag
     3001 ttcagcaatc cggacatcga cctgtcagaa ttggttttgg gtctggctgg ccatcaccaa
     3061 gaagagaatg cggccgtagc cctacaaact tttctactct atatgaccaa tattcaaaaa
     3121 gacattcaac ctcagttgat tcaacaagcc cttgcccaaa ccagctggcc tggtcgtttg
     3181 gaattggtag ttcaagagcc aaaaatctat ttggatggag cccacaatgt ccccgctatc
     3241 gaacgtttgc ttgaatttat tcaggttcaa gaagagcctg tcaccattct cttttcggcc
     3301 cttcggcgca aggactttca agaaatgctt gaattattag aagaaaaatt gccacatact
     3361 ccacttgtat taaccagctt tgcctatgat ggtgccttgg ctgaggaaaa ccgacaagga
     3421 cgagattatg ttgagaatta tcagcaattt atagaagact ggcaatctag caagcaaggg
     3481 attttgattg ttacaggctc tctctacttt atctcagaag ttcgtcggat ttttaaaaaa
     3541 tgaatatctt tttgcgaata aataggtatg acacatgcag aaaaagtagc ctttttaaaa
     3601 gaatttcaag agaacaaacg ccatactttt cgccaattag aacagtttgc aaaaatttcc
     3661 agaactcccg ataggaaatg acatcgggag tgctttttga tataataagg aaagcaaatc
     3721 caaggagaag aaaatgacag aattagatgt agtttcggac gtagttactc atcctgagga
     3781 aacttatcgg cgtagtcgta gagcatcacg tagacagcaa gtgcaactga atggtgaatt
     3841 tcatgaaaga gtattaaaga caaagtattg gccagctctt gtttggagct tagttttaag
     3901 tgtttttagc gtagccaatc cactgctaat gccatttgca accaatatac aaactcaaaa
     3961 tttatatgca gggatggcaa tggcaaatgg acaaatccct tatggtgatt tctttggtac
     4021 aagcgggtta ttattctact tacttgcttt cttaggtcat ctgggaggaa ctttcattat
     4081 ctttggaatc ctccagttta tagcattact gatagcggga gtctatttct ataagattgt
     4141 agcttatttt agtcagtcag aacacctagc gataagttct agtcattggt tctatgtatt
     4201 tatttttgca cttggttttg gagggatgta tgcagaaatg tttgctcttc cgtttctttt
     4261 gactagtgtg tggtttctgg tccgctattt tgaaaatgca gtgcgtgatg aggcatttat
     4321 cctctacgga attgatgcgg cattggtatt tttaatttac ccaaaaagtc tgatcctttg
     4381 gttagttgcg ggtctagttt tatttatttt taatatccaa caccgccaag ttactcgagg
     4441 aatctatcaa ttattagcga ccatttttgg ttttcttctg attctatatg cggtaggtta
     4501 ttatgctttt gaggcgcaga ttctggggac agctattcaa caaactttcc tttataactt
     4561 acagttagac tttcaccatt cctatctata tttagccttg gcgattgtgt ctgtattttt
     4621 actcttatct ggattcttta aaagtttcat ccaaatggtg ttttctttca aacaaggaag
     4681 acatacctat atcaaagttc tcctattatt gactttctta gttcaatgtg tctttattat
     4741 tgggaatgca aactttcaat ggagccaact cattcttctt ttaccgtatg gttttgcgat
     4801 gtcagtcgtt tacctgcgtg atgaggatgt agaagattat agtgggtatt tgcgtcgtca
     4861 attctttctt ccgttagcta tttgcttggg tattatcgct caacctgttt atctttattt
     4921 ggtacaggga gatttgagaa ctgaccgtga acaagttgcc aattacattg atgaacaaac
     4981 aaaagattcg gataagattt atgtttggga taatagcgca agcatctatc tttcaagtca
     5041 acgtttatct gctgcaacga ttactacagc agaaccctat ctgaatactg acgacaataa
     5101 aaatagcttg atgtatgaca tcaataaaaa tgaggcaaaa tttgtagtcg tcaataagaa
     5161 tttgccaatt ctagatgaaa tcaagacaaa tttagaatca cagtaccagt ctgttcagac
     5221 aacggattac tttacgattt atcaaaagaa tgaatgattg ctcaggcagt cattttttct
     5281 ttagcctatc tgggaaaagg agggaaagtg gatatgtggt ataatggaaa aataagcatt
     5341 cgggaaaaat tattaaagaa atgtaggaga aatgatgtca catattattg aactaccaga
     5401 aatactagcc aaccagattg cggctggtga ggtcattgag cgaccagcca gtgtggttaa
     5461 ggagttggtg gaaaattcca ttgacgcagg ggctagtcag attgaaatta gtgttgaaga
     5521 ggctggcctc aaaatgattc aaattacgga taacggtgag gggattgccc ctgatgaagt
     5581 agcgcttgcc ctccgccgtc acgccaccag taagataaaa aatcaatcgg atttgtttcg
     5641 tattcgcacc ctcggttttc gtggagaagc cctgccctcc attgcttctg tcagtcatat
     5701 gatcattgag acagctacgg cagactctgc acacggactt catttggagg ccaaaggtgg
     5761 tgtcatcgag aaagaggagc cagttagtcg tccagttggt acgcagatta ctgtttcgga
     5821 tttattttac aatacccctg ctcgtctcaa atatgttcgc agtcaacagg ctgaattatc
     5881 acatattgtt gatgttgtaa atcgattgag tctagctcat ccggaaatag cctttgtctt
     5941 agtaaacgaa ggacgagaat taattagaac tgcagggaca gggaaacttc gtcaggcaat
     6001 ttcagggatt tatgggattg cttctgccaa aaaaatggtt gaaattgagg cagaagatct
     6061 ggattttcag atttcaggtt atgtttcctt gccagagttg actcgtgcca accgcaacta
     6121 catttccatt tttatcaacg gtcgctatat caagaatttt ttgcttaatc gagcgatttt
     6181 ggaaggttac ggcagtaagt tgatggttgg acgctttccg ctggcagtca tttctataga
     6241 aattgacccc tatcttgctg atgtcaatgt gcatccgacc aagcaggaag ttcgcatctc
     6301 caaggaaaaa gaactcatga ccttgattcg agaggcgatt agtcaagcac ttaaagagca
     6361 ggacttgata ccagatgctc ttgagaattt agctcagtca agtactcgac caaaagtaaa
     6421 agcagagcaa ggcaccttac cactcagaga gccaaaaatc tattatgata cgattaagca
     6481 agacttcttc ttaaaaccag acgtggtcgc tgaggatgtc aaacctctcg aagaggatag
     6541 gcaagagatt gttgagtcgc ctgtcgaaaa tagacctaca tctgttcaat ttgcagaacg
     6601 tcagtcggtg gaatcagaag atcaggagca tcctaatcta agtgcaaaag aattggcaaa
     6661 actggcagat aaattagacc gggaggaaac atcgacattt ccagagttag aatattttgg
     6721 tcaaatgcat gggacgtatt tatttgcaca aggcaagaca ggactttata tcattgacca
     6781 gcatgccgca caagagaggg tcaaatacga atactaccgt gagaaaattg gacaagttga
     6841 caattcagct caacagttat tggtgccgta tatttttgaa tttccgcaga atgatgccct
     6901 tgacctcgtc cacaaaatgg atgcccttcg tcaagttggt gtcaacttgg aagaatatgg
     6961 atctaatcaa tttattctgc gtgaacatcc tatttggatg aaggaagagg agattgagtc
     7021 tggcatttat gagatgtgcg acatgttgct cttgacggat caggtgtcaa tcaagcagta
     7081 tcgggcagaa ctggccatca tgatgtcttg taaacggtca atcaaggcca atcatgcttt
     7141 ggatgattat tcggcgcgtg atttattgag acaattgtct tactgccaaa atccctataa
     7201 ttgcccgcac ggccgcccag tcttagtgca ttttagcaaa tcggatatgg aaaaaatgtt
     7261 ccgtcgcatt caagaaaatc acacgagttt gcgtgaatta gggaagtatt aacatagttg
     7321 aaaaagttga cactttagca aaggaagtat atgtacgact atattaaagg aattttaaca
     7381 aaaataactg caaaatacat tgtggtagaa acgcaaggag taggctatat cttgcaggtt
     7441 gctaatccct acgcctattc aggacaagtc cagcaagaag tgactgtcta tactcatcag
     7501 gtgattcgtg aagatgctca tttgctctac ggatttgcta cagaaaatga aaaatccgtc
     7561 tttctgagtc tgatttcagt atcaggtatt ggtccaacaa cagctctggc tattattgct
     7621 gttgatgata atgatggact tgttcgtgct atcgagcaga aaaacattac ctacctgacc
     7681 aaatttccaa agattggcaa gaaaacagcc cagcagatga ttttggactt ggaaggcaag
     7741 tttgtcatga gcgaagaagc gggtcctgtt caacaagtag caccatccag tgaaaatatc
     7801 gcccttgaag aagccatgga agccatggaa gcccttggtt accgcccagc cgaactcaag
     7861 aaaatcaaga aattctttga aggcaccaac gacaccgcag aaaactacat caagtcagcc
     7921 cttaaaatgc tgatgaagta ataagataca aaggacgtaa aggacaaaga gaaaatagac
     7981 ggccgaacag aaattttgct agaaatttag ttgtgagacc tccgcaatga caactaggta
     8041 aaaggcgagt tttgacaaag ccttttgcca gatgtcaact gcgttattcg gtgatattta
     8101 ggattcagtt tgacaatttt tcaaagtatc gtagccgtgt tcaactaacg taccagtatg
     8161 atggttaaaa agttttgttt tgttactcaa agtttgagtc aacatttcag cgcagtggtt
     8221 gattggcaga tttgttcgtg ttccacacat caaatctggc ctaatcaact gtgcgggggc
     8281 aggaagacga attctttttc tgcctgtcga attctttccc gctcccacta cagcaatcgc
     8341 tatttgcgac ttgcctaggt accttactaa ctcgccacaa aaataatgtc gatttttgtg
     8401 gctcatgtcg tgtccagata caaagggcgt aaaggacaaa gagaaaatag acggccgaac
     8461 agaaattttg caagaaattt cgttgtgaga cctccgcaat gacaactagg taaaaggcga
     8521 gttttgacga agccttttgc cagatgtcaa ctgcgttact cagtgatatg taggattcag
     8581 tttgacaatt ttgcaaagta tcgtagccgt gtttcagtct gtttatcctg attcgtactt
     8641 tagttattca cgaaaaggag tttctatgtc ccgttgtgct tgggtcaatc ccaacaatcc
     8701 actttatatt gcttaccatg atgaagaatg gggcaagcca cttcacgatg agcagtcttt
     8761 gtttgagttg ctttgcttgg aatcctacca agcaggactt tcctgggaaa ttgttctcaa
     8821 taaacgccag gcttttcgct ctgctttttt caactatgat attcaaaagg ttgcggccat
     8881 gacagatagc gagttagata gccttctgac caatccagac atcattcgtc ataaggcaaa
     8941 gctgtacgct acccgcgcca atgctcaggc ctttcttcga gtacaggagg aattcggtac
     9001 gtttgatacg tatctttggg aatgggttaa ctttacatct atcgacaacc ctgtcaagtc
     9061 cttccgagaa ttgccgacca agaacgactt gtctgagcgg atttcaaaag atttgaagaa
     9121 acgaggtttc aaatttgtag ggcctgtctg tatttactcc tatttgcagg ctgcaggtct
     9181 gttgaatgaa cacgaagaaa cttgcgagat tggaaagaaa ttacgaacta attagatgag
     9241 cgagcaatcg caccctagac agaggaggaa tatgaaagca gaactaatcg ccgttgggac
     9301 ggagattttg acaggtcaaa tcattaatac caatgctcag ttcctttcgg agaaatgtgc
     9361 agagctggga attgatgttt attttcatac ggcagttggt gacaatgaag gccgtttatt
     9421 atcaaccctt gaagtagcca gcaagcggag taatatggtc gttctttgcg gtggtttagg
     9481 accaactgag gacgacctga ccaagcagac cttggcgacc ttcttaggta gaaatcttgt
     9541 gtttgatgag ttggctatgg caaaattaga ccgtttcttt gccagtcgcc caggtcgtgt
     9601 ccgtacacca aataatgaac gtcaggcaca gattgtggag ggaagtcagg cgctacagaa
     9661 tccagctggt ttagctgttg gtggtatgat tgagcaagat ggtgtaacct atattgtttt
     9721 gcctggccca ccaagtgagc tcaaggccat gttttctgag agtctcttac ctttactgtc
     9781 ccaatctcag cagcaacttt attcgcgtgt cctacgcttt tttggaattg gcgaaagcca
     9841 gttggtgact gttttggcgg acgtgattga taagcagaca gacccaactc ttgctcctta
     9901 tgcaaaagtt ggagaggtga ctttacgctt gtccaccaaa gcgaccagcc aagaagaagc
     9961 aaatctacgt ttaaatcagt tggaagaaga catcttacaa catgacaaac tggcagacta
    10021 tttctatgcc tacggagagg acaatagttt ggtcaaaacg gtagcgactc gtttggcgga
    10081 gaaaagacaa accatcgcta tcgtcgaaca ggggacaggt ggtctcttgc aagctgaatt
    10141 gagcctggct ttggctgatc agccgtattt tagcggagga aaagtcgtcg gtcagctagg
    10201 gatagaatcg ggctggctat cagaggaagc tgactgcatt cggcaggagc tgcaagctga
    10261 tttaggtttg gctgtgtctg tgcttatcaa accggaatca acagaggaca acgtacttgc
    10321 aaaagtatac ctcactttgg ctacgccctc gggtatttcc caaaaagaga tagatttagg
    10381 tggttattcg tggcaatacc ttcgccagct tgcttgtctg caggcctggg attttgtacg
    10441 aaacactttg tgaaatagca gatatttgct ataatagttt gactaagaaa agaggagaaa
    10501 atcattggct aagaaaccag gaaaaaaatt agaagatatt acaaagaaat ttggcgatga
    10561 gcgtaaaaaa gcgttggatg atgccctaaa atcaattgaa aaagattttg gtaagggtgc
    10621 tgttatgcgt cttggtgagc gtgctgagca aaaagttcaa gtcatgagct caggtagctt
    10681 atcaatcgac attgcgcttg gagcaggtgg ctatcctaag ggccgtatca ttgagattta
    10741 cggtccagag agctcaggta agacaactgt tgctctacac gcagtagctc aagcccagaa
    10801 agatggtggt attgctgcct ttatcgatgc ggagcatgcc ttggatccag cctatgcggc
    10861 ggctcttggt gtcaatattg atgagttact attgtcacag ccagactcag gggaacaagg
    10921 tcttgaaatt gcaggcaagc tgatcgactc tggtgcggtt gacttggttg ttgttgactc
    10981 ggttgcagcc cttgtaccac gtgcagaaat tgacggtgat atcggtgata gccacgttgg
    11041 tttgcaggct cgtatgatga gccaggctat gcgcaaactc ggtgcatcca tcaacaaaac
    11101 taagacagta gctattttca tcaaccaatt acgtgaaaaa gtcggtgtca tgtttggtaa
    11161 ccctgaaaca acgcctggtg gacgtgcgct taaattctat gcatctgtcc gtatggatgt
    11221 tcgtggaaac acacaaatca aaggaacagg tgacaagaaa gatcaaaacg ttggtaagga
    11281 aaccaaggtg aagattgtga agaacaaggt ggctccacca tttaaagaag ctgttgttga
    11341 aatcatgtac ggtgaaggaa tttcttgcac aggtgaattg attgagattg gtagcaacct
    11401 cggcatcatc caaaaagcag gggcttggta ttcatataat ggagaaaaaa ttggccaagg
    11461 ttctgaaaat gctaagaaat tcttagcaga taatccagca atctttgatg aaattgaccg
    11521 caagatacgt gttcattatg gcttgattga agcagatgga gttgaagaag ttgcgaccga
    11581 agaagctcct gttgttgcgg aagaaatcca agatgttatc ctagatcttg atggcggtat
    11641 tgaattagaa gattaattcc taa
//
LOCUS       DBNFCO010000057        11598 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.057, whole genome shotgun sequence.
ACCESSION   DBNFCO010000057 DBNFCO010000000
VERSION     DBNFCO010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 11598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11598
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.057"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(52..678)
                     /locus_tag="AC1PIV_001443"
     CDS             complement(52..678)
                     /locus_tag="AC1PIV_001443"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HIP6612461.1"
                     /translation="MKIAIIAANGQAGQTIAKEAVERGHQVTAIVRSENKSVAQEVIQ
                     KDAFALTKEDLAGFDVVVNAFGAWTPETLPDHARLAEHLATILAGSPTRLLVVGGAGS
                     LYLDESQTAMLKDTPDFPAEYLPIAEAMGTGLDLYRQATAVNWTYISPAADFDAEGQK
                     SGAYTLAGEVFQVNAQGESYISYADYAVALVDIAEKGGYQQERISVLA"
     gene            complement(917..1336)
                     /locus_tag="AC1PIV_001444"
     CDS             complement(917..1336)
                     /locus_tag="AC1PIV_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HIP6612462.1"
                     /translation="MQISSRFTIASHILVLLALEGEKEKQTSTSIAGSVGVNPVIIRN
                     ILSQLKEAGLVEVARGIGGARLAQGPDQITLLHVYQAVELFGEKGQLFAFHEQPNPSC
                     QVGRNIHPLLDSRLENAQSALENELAKTRLADLLAEL"
     gene            complement(1379..2446)
                     /gene="dinB"
                     /locus_tag="AC1PIV_001445"
     CDS             complement(1379..2446)
                     /gene="dinB"
                     /locus_tag="AC1PIV_001445"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HIP6612463.1"
                     /translation="MLIFPLINDLSRKIIHVDMDAFFAAIEVRDSPALKGKPVIIGAD
                     PRLSGGRGVVSTCNYEARAFGIHSAMSSKEAYERCPQAIFISGNYEKYQEVGRQVREI
                     FHRYTDLVEPMSIDEAYLDVTENKLGISSAVKIAKLIQYDIWNELHLTASAGVSYNKF
                     LAKIASDMEKPHGLTLILPEDAVGILASLPVEKFHGVGKKTVERLHEMGVYTGQDLLD
                     VPEMVLIDRFGRFGFDLYRKARGISNSPVKVDRVRKSSGKERTYRKLLYREEDVLKEL
                     ISLCQRVAASLKRNGKKGRTIVLKVRYGDFSTLTKRHSLEVYTDQTETIEKEVRQLIE
                     EIGKIEKGIRLLGVTVTNFQT"
     gene            2762..5107
                     /gene="pflB"
                     /locus_tag="AC1PIV_001446"
     CDS             2762..5107
                     /gene="pflB"
                     /locus_tag="AC1PIV_001446"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002941480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008861 - formate C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HIP6612464.1"
                     /translation="MSTKVKTKNVAEDIFAQAWEGFKGTDWQDKASVTHFVQANYTPY
                     DGDESFLAGPTERSLHIKKIIEETKAGYEDTRFPMDVDRATSIADIPAGFIDKENELI
                     FGIQNDELFKLNFMPRGGIRMAETTLIENGYTPDPLLHEIYTKHATTVNDGIFRAYTA
                     DIRRARHSHHVSGLPDAYSRGRIIGMYARLALYGADYLMEEKVADWNAITEIDEESIR
                     LREEINMQYQALQQVVRLGDHYGVDVRKPAMNTKEAIQWTNIAFMAVCRVINGAATSL
                     GRVPIVLDIYAERDLARGTFTEAEIQEFVDDFVLKLRTVKFARTKAFDEIYSGDPTFL
                     TTSMAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWSDQLPYSFRRYCMAMSH
                     KHSSIQYEGVTTMAKDGYGEMSCISCCVSPLDPESEDQRHNIQYFGARVNVLKALLSS
                     WNNGYDDVHKDYKVFDGVEPNTSEVFDYDQVVKNFEIALDWLTDTYVDAMNIIHYMTD
                     KYNYEAVQMAFLPTHLRANMGFGICGFANTVDSLSAIKYAQVKPIRDEDGFIYDYEVT
                     GDFPRYGEDDDRVDDIAKWLMEAFFTRLNKHKLYKNAEATVSILTITSNVAYSKQTGN
                     SPVHRGVFLNEDGSVNTTKVEFFPPGANPTSKARGGWLQNLNTLSKLNFKHANDGISL
                     TTQVSPKALGKTFDEQVNNLVTILDGYFEQGGQHVNLNVMDLNDVYEKIMAGEDVIVR
                     ISGYCVNTKYLTKEQKTELTQRVFHEVLSMDDHAAEVSGQA"
     gene            complement(5514..6460)
                     /locus_tag="AC1PIV_001447"
                     /pseudo
     CDS             complement(5514..6460)
                     /locus_tag="AC1PIV_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002941482.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
     gene            complement(6457..7191)
                     /locus_tag="AC1PIV_001448"
     CDS             complement(6457..7191)
                     /locus_tag="AC1PIV_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA N-terminal domain-containing protein"
                     /protein_id="HIP6612465.1"
                     /translation="MLRKNEAIVPILRINNRAINQGFLEENLGMKTKLEDGPFADFGD
                     RTSPEAKLVLTESPGNRTRAVEGLKKLNKIVIKVDNASEIEALLAQGSQYSKLYQGKN
                     GYGFEALSPEGDTFLLHAEASVDDLKAILPPVPFKVQDDFSGLTAFTVESVWINTPQA
                     SISQDYYEAILPQQAFLRFVGAEGKDLLTPAEQVWDLEGLRFPVEQDFDWAHLESRLE
                     RPFFKDKKASFIQTVDPSGIELWFEK"
     gene            7373..9640
                     /locus_tag="AC1PIV_001449"
     CDS             7373..9640
                     /locus_tag="AC1PIV_001449"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002941485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008239 - dipeptidyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HIP6612466.1"
                     /translation="MRFNQFSFIKKETSVYLQELDTLGFQLIPDASSKTNLETFVRKC
                     HFLTANTDFALSNMIAEWDTDLLTFFQSDRELTDQIFYQVAFQLLGFVPGMDYTDVMD
                     FVEKSNFPIVYGDIIDNLYQLLNTRTKSGNTLIDQLVSDDLIPEDNHYHFFNGKSMAT
                     FSTKNLIREVVYVETPVDTAGTGQTDIVKLSILRPHFDGKIPAVITNSPYHQGVNDVA
                     SDKALHKMEGELAEKQVGTIQVKQASITKLDLDQRNLPVSPATEKLGHITSYSLNDYF
                     LARGFASLHVSGVGTLGSTGYMTSGDYQQVEGYKAVIDWLNGRTKAYTDHTRSLEVKA
                     DWPNGKVATTGLSYLGTMSNALATTGVDGLEVIIAEAGISSWYDYYRENGLVTSPGGY
                     PGEDLDSLTALTYSKSLQAGDFLRNKAAYEKGLAAERAALDRTSGDYNQYWHDRNYLL
                     HADRVKCEVVFTHGSQDWNVKPIHVWNMFHALPSHIKKHLFFHNGAHVYMNNWQSIDF
                     RESMNALLSQKLLGYENNYQLPTVIWQDNSGEQTWTTLDTFGGENETVLPLGTGSQTV
                     ANQYTQEDFERYGKSYSAFHQDLYAGKANQISIELPVTEGLLLNGQVTLKLRVASSVA
                     KGLLSAQLLDKGNKKRLAPIPAPKARLSLDNGRYHAQENLVELPYVEMPQRLVTKGFM
                     NLQNRTDLMTVEEVVPGQWMNLTWKLQPTIYQLKKGDVLELILYTTDFECTVRDNSQW
                     QIHLDLSQSQLILPH"
     gene            complement(9917..>11598)
                     /locus_tag="AC1PIV_001450"
     CDS             complement(9917..>11598)
                     /locus_tag="AC1PIV_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="GAG-binding domain-containing protein"
                     /protein_id="HIP6612467.1"
                     /translation="TANKKFRYSIRKFKVGVGSVLIATCLLGAGVSTPTAFATTETST
                     ATQVEAMAKVEEVQKLVKELEKELGELDKVPSYGDAQDYSYQKALWEEFLRIGKDNMD
                     YASKMKADDKFFHKVKGDLNDFKYQIKVENYIRQVAELRKKYPGDNTIEEEYNAHLKQ
                     DEGKSIASQEGATLRDYVDREASEAMGRIKQRVAELEKSKQPQPSPADEPAPAPKEEE
                     TPAPKEEDTPAPDAAPAPAPTPEVDPAPTPIPDTPKAEEEAPTPVPDTPAPKEDEVPA
                     PIPDAPTPKVEEETQEPKTEEKAPETKEETPTPVPDTPAPKEDEVPAPMPDAPAPKAE
                     EEVPAPTPMPETPMDKPKTDKVESDKQMPEAKQPEMEQPKAEDMPKEEMPKSEQPKAE
                     DSAPKTAVPEVAPKTAEKPKLDFTTKERKVEEALPIKEEIRYDASLPLGKSYLLQEGK
                     AGKKVSVYQDVIVDGKVVATNLLSETVVEGQNRILVKGSLEMKKEEVKTTPSVQSNPT
                     LSHKGAPSANKATLPATGEQRNNLALVGLGLAGISLAVVATAINKKSKDQI"
BASE COUNT         3207 a         2751 c         2333 g         3307 t
ORIGIN      
        1 aaataaaaag ataattcctc gatggagcta tcttttagac catttaattt tttatgcaag
       61 tacggaaatt cgttcctgct ggtagccacc tttttccgca atgtcaacca aagccacagc
      121 atagtcggca taactaatat agctttcacc ttgggcattg acttggaaaa cctcgccagc
      181 caaagtgtag gcacctgatt tttgaccttc tgcatcaaaa tctgctgctg ggctgatata
      241 ggtccagttg accgctgtcg cctgacgata gaggtctaga ccagtaccca tagcctcagc
      301 gattggcagg tattccgcag ggaaatctgg tgtatctttc agcatagctg tctggctctc
      361 gtctaaataa agactgcctg caccaccaac tactaaaaga cgagttggac taccagcaag
      421 tatggtcgct agatgctcag caagacgggc gtgatccggc aaggtttctg gtgtccaagc
      481 accaaaagca ttaactacta catcaaagcc tgccaaatct tctttggtaa gagcaaaagc
      541 atccttctgg attacttctt gggctacgct cttgttttca gaacggacaa tagccgtcac
      601 ctgatgacca cgttctactg cttcctttgc aatagtttga cctgcttgac cattcgctgc
      661 aataatagca attttcatat tgatacctca cttgttttgt tgtaacaact ttatttacaa
      721 cgtaagtata aatctttttg attgtaaagt caattgttac aactcaaaaa tttaaaaaat
      781 catcacaagg atgattcact aaccagtctt ttagtgctag ggcaacactc tacagattac
      841 ttcaacagtc cagtggagtg tttgaagtag gaaataggga aacaaagttt ctccttacgt
      901 tgacctaata aaacgactat agttccgcca agagatcagc aagccttgtc ttagcaagtt
      961 cattttccaa agctgactga gcattttcca aacggctatc tagcagagga tgaatattgc
     1021 gacctacttg acaggaagga ttcggttgct catgaaaagc gaataattga cctttttctc
     1081 caaataactc cacagcctga tagacatgca aaagtgtaat ctggtctgga ccctgtgcca
     1141 agcgagcacc tccaatacca cgcgctactt ctaccagacc agcctccttg agttgggaca
     1201 aaatatttcg gataatgaca ggattaaccc cgacactgcc tgcaatgcta gtactggtct
     1261 gtttttcttt ttctccttcc agagccaaga gaaccaagat atggctggca atggtaaatc
     1321 tacttgaaat ttgcatctct tctccttttt ttcagtctat catagactga aacagaactc
     1381 aagtttgaaa attagtcacg gtcacaccca gcaaacgaat ccctttttca atcttcccaa
     1441 tttcttcaat tagttgacga acctctttct caatcgtttc cgtctggtcc gtatatacct
     1501 ctagactatg acgtttcgtc aaggtagaaa aatcaccata acgaaccttt aaaacaattg
     1561 ttcgaccctt ttttccattt cgcttcaaac tggctgcgac ccgttggcag agactgatta
     1621 gctctttcag gacatcctcc tcccgataaa gaagtttgcg ataggttctt tcctttccac
     1681 ttgacttacg aacacggtcc actttaacgg gcgaattaga aatccccctc gctttccgat
     1741 aaaggtcgaa gccaaaacgc ccaaatctat ctatcaaaac catttctggt acatctagca
     1801 aatcttgccc cgtgtagacc cccatctcat gcaggcgttc caccgtcttc ttccccacac
     1861 cgtgaaattt ttcaacaggc agggaggcga gaataccaac agcatcttca ggtagaatca
     1921 aggtcaaacc gtgcggtttt tccatatcag aggcaatttt tgccaaaaat ttattatagg
     1981 aaacacctgc ggaagctgtc agatgcaatt cattccaaat atcgtattgg ataagcttgg
     2041 caatcttaac cgcagagctg atgcccaact tattttctgt tacatccaag taagcctcat
     2101 cgatagacat gggctccacc aaatcagtat agcgatggaa aatttctcga acctgtcgcc
     2161 caacttcctg atatttttca taattgccag aaatgaaaat cgcctgagga caacgctcat
     2221 aagcctcttt tgaggacata gccgagtgaa tcccaaaggc acgcgcctca taattacagg
     2281 tagacaccac tcctctaccg ccagatagtc ttgggtcagc cccaatgata acaggtttgc
     2341 ccttcaaagc agggctatcc ctgacctcaa tggcagcaaa aaaagcatcc atatctacat
     2401 gaataatttt tctagataaa tcattgatta agggaaaaat taacatgact gcctcttcct
     2461 gtttacaagt ttaactcgct atattatacc gcatttctta ggaagtttca gcctttagat
     2521 tcgttgaacc agccatctta ccaatacaat aaacgacagc ttatcacctt attacaaata
     2581 caagcagaaa tttattttga aaataccaac tctatatttc aatttttttc atattccttg
     2641 aaaggttttt catttatttt caagtatttt tgtcttgtag aaagtgtttt caaatggtat
     2701 aataatgaca tgttggtatc gatagcaagt cgatacccaa aagcataaaa ggagaaccct
     2761 catgtcaaca aaagttaaaa caaaaaatgt tgctgaagac attttcgccc aagcctggga
     2821 aggctttaaa ggtacagatt ggcaagataa ggcaagtgta acacacttcg ttcaagccaa
     2881 ctacactcca tacgatggag atgaaagctt cctcgcaggc ccaactgagc gttcacttca
     2941 tatcaaaaaa atcatcgaag aaacaaaagc tggctacgaa gacactcgct tcccaatgga
     3001 cgtagatcgt gctacttcta tcgctgatat tccagcaggt ttcatcgata aagagaacga
     3061 actcatcttc ggtatccaaa acgatgagct cttcaaactc aatttcatgc cacgtggtgg
     3121 tattcgtatg gctgaaacaa ctcttatcga aaacggctat actccagacc cactccttca
     3181 tgaaatctat acaaaacacg ctacaactgt aaacgacggt atcttccgtg cctacaccgc
     3241 tgacatccgt cgtgctcgcc actcacacca cgtttctggt cttccagatg catactcacg
     3301 tggtcgtatc atcggtatgt acgctcgttt ggcactttac ggtgcagact acttgatgga
     3361 agaaaaagta gctgactgga atgccattac tgaaatcgat gaagaatcaa tccgtcttcg
     3421 tgaagaaatc aacatgcagt accaagcatt gcaacaagtt gtacgcttag gtgatcacta
     3481 tggtgttgat gttcgcaaac ctgcaatgaa cactaaagaa gctatccaat ggacaaacat
     3541 tgctttcatg gctgtatgtc gtgttatcaa cggtgcagca acttctcttg gtcgtgtgcc
     3601 aatcgtactt gacatctacg ctgaacgtga tttggctcgt ggtacattta ctgaggctga
     3661 aatccaagaa tttgttgatg acttcgtatt gaaacttcgt acagtgaaat tcgctcgtac
     3721 aaaagccttc gacgaaatct actctggtga cccaacattc ttgacaacat ctatggcagg
     3781 tatgggtaac gatggtcgtc accgtgttac taagatggac taccgtttct tgaacacact
     3841 tgacaacatc ggtaactctc cagaaccaaa cttgacagtt ctttggtcag accaacttcc
     3901 atattcattc cgtcgctact gtatggcaat gagccacaaa cactcttcta tccaatatga
     3961 aggtgtgaca acaatggcga aagatggtta tggtgaaatg tcatgtatct cttgctgtgt
     4021 atctccactt gatccagaaa gcgaagacca acgccacaac atccaatact ttggtgctcg
     4081 cgtaaacgtc cttaaagccc ttctttcaag ctggaacaac ggttacgatg acgttcacaa
     4141 agattacaaa gtattcgacg gtgttgaacc aaacacatct gaagtatttg actacgacca
     4201 agtggttaag aactttgaaa tcgcccttga ctggttgact gatacatatg ttgatgccat
     4261 gaatatcatc cactacatga cagataaata caactacgaa gcagttcaaa tggcattctt
     4321 gccaactcac cttcgtgcta acatgggctt cggtatctgt ggtttcgcaa acactgttga
     4381 ctcattgtca gcaatcaagt atgcacaagt taaaccaatc cgtgatgaag atggatttat
     4441 ctacgactac gaagtaactg gtgacttccc acgctatggt gaagacgatg accgtgtaga
     4501 tgatattgcg aaatggctca tggaagcatt cttcactcgt ttgaacaaac ataaattgta
     4561 caagaatgct gaagctacag tatctatctt gacaatcact tctaacgttg cttactctaa
     4621 acaaacaggt aactctccag ttcaccgtgg tgtattcctc aatgaagatg gttctgtgaa
     4681 cactactaag gtagaattct tcccaccagg tgctaaccca acttctaaag ctcgtggtgg
     4741 ttggttgcaa aacttgaata ccctttctaa actcaacttc aaacatgcca acgacggtat
     4801 ctcattgact actcaagttt ctccaaaagc gcttggtaaa acattcgatg agcaagtaaa
     4861 caacttggta acaatccttg atggttactt tgagcaaggt ggtcaacacg ttaacttgaa
     4921 cgttatggac ttgaacgacg tttatgaaaa aatcatggct ggtgaagatg ttatcgttcg
     4981 tatctctgga tactgcgtaa acactaaata cctcactaaa gagcaaaaaa ctgaattgac
     5041 tcaacgtgtc ttccacgaag ttctttcaat ggacgaccac gctgctgaag tttcaggtca
     5101 agcttaatca agcagacaca aaaggacttg cacatgcagg tccttttact atgtcgaaaa
     5161 atctactgag tgttgcggaa ggatagttat agtcttttag tttactttta gtactaggca
     5221 acgagctgcg gacagcttgt acagtcgagt gactgtgcaa ggttggagat agcacttgcg
     5281 gagcaagtcc cccctgcaga gtacggcaaa gcgagttcaa atactccagt ggagtgtttg
     5341 aagttggaaa taaggaaacg atgtttcctc gatcgtcgaa gtaataaaag aaaaactaaa
     5401 tgactgatat atactcaatg aaaatcaaaa gtagcctaag aaacgaagtc gaagatagaa
     5461 ctggagttca ttaaggcaag ttgacaatgg ataattttga ttttcgaaga gtattagtca
     5521 atagcctctt cttcctccaa gacctgacga atcaaggcca taacctggtt tctatccaac
     5581 ttccactggg cgcgctcatc cttgtcaaaa gtacgattcg agagaaaaat cgcagctttc
     5641 tgcaagggac ggttatacat gataaaggtc cccgtatagc ctgtgtgcga caaccagtcc
     5701 cccttcttat cccaagccag agaccgcttg cgtttatcat caaaaccgta atcctgcgtt
     5761 aaattcgccg caaaatcctc agttagatag cgctccaaaa agatttccaa atctttgacg
     5821 gtcgaaaaga gacctgcact tcccgcgtgg aggcccaaga cacgcgcctt gggatcatgc
     5881 accacacctg ctttgacgcc acgaaccgtc ggcaccgcct gactgactgg tccaaaggag
     5941 gttcggaaca taccaaaggg ctctagaacg tctcgactaa tcagctggtc tagactgtct
     6001 ctacccaatt cctccaacaa aaagcccagt aagagaaaat taatatccgt gtagaggaaa
     6061 gctttcttat ccgttacagc aatcttcaaa atcgcttcct tgagctggtc ggcatccaga
     6121 ctatccctat ttggaataaa gggatcaata ccactagtat gggtcaataa ttgccgaatg
     6181 gtgacctcac tatccgcaaa agctggataa taagactgca aggtcctatc tagctccaaa
     6241 gctccgctat taaccaaaaa agtcgcaaga gtccctactc caaccacctt agaaacagac
     6301 gccaaatcat aggtcaaacc cgcctcaact ggcgtatgcc catcctgggt ccctagatag
     6361 tactcctgcc actgaccatc agaaaaaaag ccagactgac accaggatat actccttgct
     6421 caatctgctc tgaaaccttg tctaaaatta cttgtctcat ttttcgaacc acaattcaat
     6481 accacttggg tcaactgttt ggataaagct cgctttttta tctttaaaga atggtctttc
     6541 caaccggctt tccaaatgcg cccaatcaaa gtcttgctcg acgggaaaac gcaagccttc
     6601 taaatcccaa acttgttctg caggagttaa taaatcctta ccttctgctc caacaaaacg
     6661 caaaaaggct tgttgaggta ggatagcctc ataatagtct tgactaatac tagcttgtgg
     6721 ggtattaatc cagacagact ctactgtaaa agcggtcaga ccagaaaagt catcctgcac
     6781 cttaaatgga acaggtggaa ggattgcttt taggtcatca acagatgctt ctgcgtgtaa
     6841 aagaaaggtg tctccttctg gcgaaagagc ttcaaaacca tagccatttt ttccttggta
     6901 gagcttacta tactgtgacc cttgcgccag taaagcttca atttcagagg cattgtctac
     6961 ttttatcaca attttattca gttttttaag cccttcgaca gcacgggtgc gattaccagg
     7021 agattctgtc aaaacgagct tcgcttctgg acttgttcta tctccaaaat cagcaaaagg
     7081 accatcttcg agcttggttt tcattcctag attttcttct aaaaatcctt ggttaatagc
     7141 cctattatta atacgtaaaa tagggactat agcttcattt tttctcaaca cgatacattt
     7201 cactcctcag tcattctaca atattgtata aaaattttca tcattttaca agtaattgta
     7261 tcgtcgtttt atacattaat atctctatat atactgataa tttttagaca aacattgact
     7321 tatccgatat aatagctatt atagactatt atcctaaaaa agaggagaat ttatgcgctt
     7381 taatcaattt tctttcataa aaaaagagac ctccgtctac ttgcaagaac ttgatactct
     7441 gggatttcaa ctgattcctg atgcaagtag taagacaaat ttagaaacct ttgtcagaaa
     7501 gtgccatttc ctgacagcaa acaccgactt tgccctgtca aacatgatcg cagaatggga
     7561 cacagatctt ctgaccttct tccagtctga ccgtgagttg actgaccaga ttttctatca
     7621 agtcgccttt cagttgctgg gctttgtgcc tggtatggat tatacagatg tcatggattt
     7681 cgtggagaaa agcaacttcc cgattgtcta tggggacatc attgacaacc tctaccagct
     7741 cctcaatact cgcaccaagt ctggaaacac cttgattgac cagctagtca gcgatgacct
     7801 gattccagag gacaatcact accacttctt caacggcaaa tctatggcaa ccttttcaac
     7861 caaaaacctt attcgtgagg tggtctatgt cgaaacgcct gttgatacag ctgggactgg
     7921 gcagacagat attgttaagc tgtccatcct ccgtcctcac tttgacggga aaatccctgc
     7981 ggtgattaca aatagtcctt atcatcaagg agttaacgat gtagccagcg ataaggctct
     8041 gcataagatg gaaggggaac tggctgaaaa acaagtcggt accattcagg tcaagcaggc
     8101 cagcatcacc aagttagact tggaccaacg gaacctgcct gtcagccctg ctactgaaaa
     8161 actggggcac attacttcgt actccctcaa tgactacttc ctcgctcgcg gctttgccag
     8221 cctccatgtg tctggtgttg gcacgctggg ctcgacgggc tacatgacat ctggcgacta
     8281 ccaacaggtg gagggctata aagcggtgat tgactggctg aacggtcgca ccaaggccta
     8341 cacagaccac actcgctcgc ttgaggtcaa ggccgattgg cccaatggta aggtagcgac
     8401 gacgggactg tcttatctcg gtaccatgtc caatgccttg gcaacaactg gcgtggacgg
     8461 attggaagtc atcatcgcag aagcagggat ttcctcttgg tatgactact accgtgaaaa
     8521 cgggctggtg accagccctg gtggctatcc aggcgaagat ttggacagct tgaccgccct
     8581 gacctactcc aagagtttgc aagcaggtga cttcctccgc aataaagcag cctacgaaaa
     8641 aggactggct gccgagcgtg ctgccctgga ccgcaccagc ggtgactaca atcaatactg
     8701 gcatgaccgc aattatctgc tccacgctga tagggtcaag tgtgaggtgg tctttaccca
     8761 cggctcacag gactggaatg tcaagccaat ccatgtctgg aatatgttcc atgccctacc
     8821 tagtcacatc aagaagcacc tcttcttcca caacggtgcc cacgtttata tgaacaactg
     8881 gcagtctatc gacttccgcg agtccatgaa cgccctgctc agtcagaaac tactgggcta
     8941 cgagaacaac taccaactgc caacggttat ctggcaggac aacagcggtg agcaaacttg
     9001 gacgaccttg gacacctttg gcggtgaaaa cgagactgtc ttgccactag gtactggaag
     9061 ccagaccgtt gccaatcagt atacccaaga agattttgaa cgctacggca aatcctactc
     9121 tgccttccac caagacctct atgcaggcaa agccaatcaa atcagcattg aactgcctgt
     9181 aacggagggc ctcttgctta acgggcaggt cacgctgaaa ctccgtgtcg cttctagtgt
     9241 agctaaaggc ctcttatccg ctcagctatt ggacaaggga aataaaaaac gcctagcccc
     9301 aatccctgcg cctaaagcaa gattgagtct agacaacggt cgttaccatg cccaagaaaa
     9361 tctggtggag ttgccctatg tggagatgcc acaacgcttg gtaaccaagg gctttatgaa
     9421 cctgcaaaac cgcaccgacc tgatgactgt cgaggaagtg gtgcctggac agtggatgaa
     9481 tctgacctgg aaactgcagc cgaccattta tcagctgaaa aaaggcgatg tcttggagtt
     9541 gattctctat acaaccgact ttgagtgtac tgttcgggat aattctcaat ggcaaatcca
     9601 ccttgattta agtcaatcac agttaatttt accgcactaa tactcaatga aaatcaaaat
     9661 cagactagtt tcaaaggttt tggaaacctt tgaaggttgg agatagagtg aacgaagttc
     9721 gtttctccaa gagcagatat acccctgcta ctttcttatt ttatggtagc aggctgtcaa
     9781 gctccactgg agcttgacac tcatcaaatc aagtcaacaa cgtctgattt tgagtttcga
     9841 agagtataat attgattttc agttctaaaa agaggctggg cgtttccgcc ctgcctcttt
     9901 attatttcat aatggtttag atttgatctt tagatttttt gtttatagct gtagcgacta
     9961 ccgccaagct aattccagct aaaccaaggc ctactaaggc taggttattg cgctgttcac
    10021 ctgttgcagg tagggttgct ttgtttgcag aaggtgcgcc cttatgactt agtgtcggat
    10081 ttgattgtac tgaaggagtt gtttttactt cttctttctt catttccaag ctacctttta
    10141 caaggatacg attttgacct tcaacaacag tttctgataa taggttggtt gcgacaactt
    10201 taccatcaac tatgacatct tgataaacag atactttttt acctgctttt ccttcttgaa
    10261 gaaggtatga tttgccaagc ggtaggcttg catcatatct gatttcttct ttgataggga
    10321 gagcttcttc taccttgcgt tcttttgttg tgaagtctag ctttggtttt tccgctgttt
    10381 ttggtgcgac ttctggaact gctgtcttag gtgcagagtc ttccgctttt ggttgctcag
    10441 actttggcat ttcctccttc ggcatgtctt ctgctttcgg ttgctccatt tctggttgct
    10501 tagcctctgg catctgtttg tcagactcta ctttatcagt tttcggtttg tccattggag
    10561 tttctggcat tggagttggg gctggaactt cttcctctgc tttcggcgct ggagcatctg
    10621 gcattggtgc cggaacttcg tcctctttcg gtgccggagt gtccggtact ggagttggag
    10681 tttcttcttt cgtctctggt gccttctctt ctgttttcgg ctcctgtgtt tcctcttcta
    10741 ctttcggtgt tggagcgtct ggaattggtg ccggaacttc gtcctctttc ggtgccggag
    10801 tgtccggtac tggagttgga gcctcttcct ctgcctttgg agtgtctgga attggagttg
    10861 gagctggatc cacttccggt gttggagctg gagctggggc tgcgtccggt gccggagtgt
    10921 cctcctcttt tggagctggg gtttcttcct cttttggagc tggagctggc tcatctgcgg
    10981 gacttggctg gggttgtttt gatttttcca gttcagcaac tcgttgctta attctgccca
    11041 tggcctcact tgcttctcta tcaacgtagt ctcttaaggt agcgccctct tggctagcta
    11101 tactcttgcc ttcgtcttgc tttaaatgcg cattatattc ttcctcaatt gtattatcac
    11161 cagggtattt ctttcgcaat tctgcaacct gacggatata gttttccact tttatttgat
    11221 atttaaaatc attcaaatcc cctttaacct tatggaaaaa cttgtcatct gctttcattt
    11281 ttgaagcata gtccatatta tcttttccaa ttcttaaaaa ctcttcccac aaagccttct
    11341 gataagaata atcttgagca tcaccataac ttggaacctt atctagttcc cccagctctt
    11401 tttctaattc tttcacaagc ttctgaactt cttcaacttt cgccattgct tcaacttgag
    11461 tagctgttga agtctctgtc gtcgcaaaag cggttggtgt cgagactccc gcaccaagta
    11521 agcaagtagc aatcagcacc gagcctacgc cgactttaaa tttacgaata ctatatctga
    11581 attttttatt tgcagttt
//
LOCUS       DBNFCO010000058        11063 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.058, whole genome shotgun sequence.
ACCESSION   DBNFCO010000058 DBNFCO010000000
VERSION     DBNFCO010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 11063)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11063)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11063
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.058"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(201..1074)
                     /locus_tag="AC1PIV_001451"
                     /pseudo
     CDS             complement(201..1074)
                     /locus_tag="AC1PIV_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681261.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            complement(1271..2503)
                     /locus_tag="AC1PIV_001452"
     CDS             complement(1271..2503)
                     /locus_tag="AC1PIV_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidylyltransferase domain-containing protein"
                     /protein_id="HIP6612468.1"
                     /translation="MEPICLIPARSGSKGLPNKNMLFLDGVPMIFHTIRAAIESGCFK
                     KENIYVSTDSEVYKEICETTGVQVLMRPADLATDFTTSFQLNEHFLQDFSDDQVFVLL
                     QVTSPLRSGKHVKEAMELYGKGQADHVVSFTKVDKSPTLFSTLDENGFAKDIAGLGGS
                     YRRQDEKTLYYPNGAIYISSKQAYLADKTYFSEKTAAYVMTKEDSIDVDDHFDFTGVI
                     GRIYFDYQRREQQNKPFYKRELKRLCEQRVHDSLVIGDSRLLALLLDGFDNISIGGMT
                     ASTALENQGLFLATPIKKVLLSLGVNDLITDYPLHMIEDTIRQLMESLVSKAEQVFVT
                     TIAYTLFRDSVSNEEIVQLNDVIVQSASELGISVIDLNEVVEKEAMLDYQYTNDGLHF
                     NQIGQERVNQLILTSLTR"
     gene            complement(2512..3162)
                     /locus_tag="AC1PIV_001453"
     CDS             complement(2512..3162)
                     /locus_tag="AC1PIV_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HIP6612469.1"
                     /translation="MIDRGESLMKKVAFLGAGTFSDGVLPWLDRSRYELIGYFEDKPI
                     SDYRGYPVFGPLQDVLTYLDDGKVDAVFVTIGDNVKRKEIFDLLAKDHYDALFNIISE
                     QANIFSPDSIKGRGVFIGFSSFVGADSYVYDNCIINTGAIVEHHTTVEAHCNITPGVT
                     INGLCRIGEGTYIGSGSTVIQCIEIAPYTTLGAGTVVLKSLTESGTYVGVPARKIK"
     gene            complement(3152..4285)
                     /gene="neuC"
                     /locus_tag="AC1PIV_001454"
     CDS             complement(3152..4285)
                     /gene="neuC"
                     /locus_tag="AC1PIV_001454"
                     /EC_number="3.2.1.183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008761 - UDP-N-acetylglucosamine
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0006047 - UDP-N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase"
                     /protein_id="HIP6612470.1"
                     /translation="MKKICFVTGSRAEYGIMRRLLSYLQDDPEMELDLVVTAMHLEEK
                     YGMTVKDIEADKRRIVKRIPLHLTDTSKQTIVKSLATLTEQLTVLFEEVQYDLVLILG
                     DRYEMLPVANAALLYNIPICHIHGGEKTMGNFDESIRHAITKMSHLHLTSTDEFRNRV
                     IQLGENPNHVLNIGAMGVENVLKQDFLTREELAMELGIDFAEDYYVVLFHPVTLEDNT
                     AEEQTQALLDALKEDGSQCLIIGSNSDTHADKIMELMHEFVKQDSDSYIFTSLPTRYY
                     HSLVKHSQGLIGNSSSGLIEVPSLQVPTLNIGNRQFGRLSGPSVVHVGTSKEAIVGGL
                     GQLRDVIDFTNPFEQPDSALQGYRAIKEFLSVQASTMKEFYDR"
     gene            complement(4297..5313)
                     /gene="neuB"
                     /locus_tag="AC1PIV_001455"
     CDS             complement(4297..5313)
                     /gene="neuB"
                     /locus_tag="AC1PIV_001455"
                     /EC_number="2.5.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0016051 - carbohydrate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HIP6612471.1"
                     /translation="MVYIIAEIGCNHNGDVHLARKMVEVAVDCGVDAVKFQTFKADLL
                     ISKYAPKAEYQKITTGESDSQLEMTRRLELSFEEYLDLRDYCLEKGVDVFSTPFDEES
                     LDFLISTDMPVYKIPSGEITNLPYLEKIGRQAKKVILSTGMAVMDEIHQAVKILQENG
                     TTDISILHCTTEYPTPYPALNLNVLHTLKKEFPNLTIGYSDHSVGSEVPIAAAAMGAE
                     LIEKHFTLDNEMEGPDHKASATPDILAALVKGVRIVEQSLGKFEKEPEEVEVRNKIVA
                     RKSIVAKKAIAKGEVFTEENITVKRPGNGISPMEWYKVLGQVSEQDFEEDQNICHSAF
                     ENQM"
     gene            complement(5836..7242)
                     /locus_tag="AC1PIV_001456"
     CDS             complement(5836..7242)
                     /locus_tag="AC1PIV_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0140327 - flippase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HIP6612472.1"
                     /translation="MSKKSIVVSGLVYTIGTILVQGLAFITLPIYTRVISQEVYGQFS
                     LYNSWVGLVGLFIGLQLGGAFGPGWVHFREKFDDFVSTLMVSSIAFFLPIFGLSFLLS
                     QPLSLLFGLPDWVVPLIFLQSFMSVVQGFFTTYLVQRQQSMWTLLLSVLSAVINTALS
                     LFLIFSMENDFIARVMANSATTGVFACVSLLFFYKKIGLHFRKDYLRYGLSISIPLIF
                     HGLGHNVLNQFDRIMLGKMLTLSDVALYSFGYTLASILQIVFSSLNTVWCPWYFEKKR
                     GADKDLLSYVRYYLAIGLFVTFGFLTIYPELAMLLGGSEYRFSMGFIPMIIVGVFFVF
                     LYSFPANIQFYSGNTKFLPIGTFIAGVLNISVNFVLIPTIGIYGAALATTASYLLLLV
                     LHYFVAKKKYAYDEVAISTFVKVIALVVVYTGLMTVFVGSIWIRWSLGIAVLVVYAYI
                     FRKELTVALNTFREKRSK"
     gene            complement(7251..8222)
                     /locus_tag="AC1PIV_001457"
     CDS             complement(7251..8222)
                     /locus_tag="AC1PIV_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 52"
                     /protein_id="HIP6612473.1"
                     /translation="MRRIYICHTMYQILISLLKMDVERDSLMSVDIIGHFPDVREQLQ
                     QHVHLIEETERSFDLYSLIARSKTKERLSLLQSYDEVIIFQDHRQVGHFLNKHRIPYS
                     LLEDGYNFFKDKRVCDLESIQSSVWKRLFYQWYFKPTYLIGSSLYCQSIEVNDLSLVQ
                     FDEAYKPFVEVPRKQLFDQASPEKVQALLQIFGARAIVADEESSQKRLLLLTQPLSWD
                     YHVTEEELLEIYVAGLAPYREDYTIYIKPHPRDGVDYSFLGKAVVLLPQGIPFELFEM
                     AGSIRFDIGMTYSSSALDFLNCFEEKVYLKDTFPLLSKNDILREGIE"
     gene            complement(8659..8772)
                     /locus_tag="AC1PIV_001458"
                     /pseudo
     CDS             complement(8659..8772)
                     /locus_tag="AC1PIV_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936306.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cytidylyltransferase domain-containing protein"
     gene            9379..9603
                     /locus_tag="AC1PIV_001459"
     CDS             9379..9603
                     /locus_tag="AC1PIV_001459"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612474.1"
                     /translation="MKVSTLERTSCFERKNQALEQKDNEVILVYIYMPCSAMLANMAS
                     TEKFTKKQVSKPNHLFFSKRTYKIGNKKTT"
     gene            complement(9714..10025)
                     /locus_tag="AC1PIV_001460"
     CDS             complement(9714..10025)
                     /locus_tag="AC1PIV_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009909574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612475.1"
                     /translation="MNPTNSRIALFDTIKCIMVLCVIFTHLDWSVEQRQWFIFPYFVD
                     MAVPIFLLLSAYFRTNKWNTKQETLKLKFSSGIKESINMLCLYAIVMAVNVLLSYSRT
                     I"
     gene            complement(10065..>11063)
                     /locus_tag="AC1PIV_001461"
     CDS             complement(10065..>11063)
                     /locus_tag="AC1PIV_001461"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009909571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HIP6612476.1"
                     /translation="NISIIVPIYNVEQYLSKCINSIVNQTYKHIEILLVNDGSTDNSE
                     EICLAYAKKDSRIRYFKKENGGLSDARNYGISRAKGDYLAFIDSDDFIHSEFIQRLHE
                     AIERENALVAVAGYDRVDASGHFLTAEPLPTNQAVLSGRNVCKKLLEADGHRFVVAWN
                     KLYKKELFEDFRFEKGKIHEDEYFTYRLLYELEKVAIVKECLYYYVDRENSIITSSMT
                     DHRFHCLLEFQNERMDFYESRGDKELLLECYRSFLAFAVLFLGKYNHWLSKQQKKLLQ
                     TLFRIVYKQLKQNKRLALLMNAYYLVGCLHLNFSVFLKTGKDKIQERLRRSESSTR"
BASE COUNT         3525 a         2425 c         1895 g         3218 t
ORIGIN      
        1 atggaggaat gtgtgattgg atagatacct tgttattagg cggttacgct ttaaacatca
       61 aaaatgagag aacgaatttc gtcctctcta ggtgttagct tttcgtctac ccactacagt
      121 tgacaaagag ccgttttttt attgtgagaa actagttttt gcccagcctc tttttgctta
      181 ttttcctatt tttgggcgca ctaagcccac gatggtaatc ccagtcgttt gatttgctca
      241 aaacgacaga tattgtagag caggttggtt aaggtcacat tggtttcagc tcgtgccttc
      301 ccaattgctc gacagatgtt acctttcatg ttagtttcaa tgaagccaaa accatgctca
      361 acgcgacaac ggactttggt aatatgtcga ttaatgacct tatcagtctc agtcaacggt
      421 ttatttctaa aagcacgacg aatcgtgtgg tggcgacaac cttctggtac tgattttcca
      481 acataagcac tgtcatcaaa aaccgcttca ttggcatcac aaagaggagc taggacattg
      541 gagtcgtgta cactagctgt tgtgacctca taattttcga taagttttga ttttctgatt
      601 gtcctcacgt gaattgcgtt gtttagggca ttcgacaaag gtagcatcca caatctgacc
      661 tgaatgggca atcacccctt catctgtgag atgggcatag aacaaatcga acaactcctt
      721 ttcacgacct gacttggtta atttctcacg atagagccag atagttttcg catcgggaac
      781 agtgtcttca tgacaaccaa caaaacgacg aaaagatata cgatccagca gttgatattc
      841 catggcatcg tcagataggt tatgaagacg ttgaagcaag agcgctttga acatcatgag
      901 atagtctagg tgaggacgac cgccacgact gatgacttta tctttacgac tgaataactc
      961 tgacaacaat ggaagaaaga tattccaatc cataacggca tccaaacgtt ctaagggatt
     1021 gcctttctct gatagttttg acaagatttt ttcatcgtct gtgaataaat gcatgacagc
     1081 tctcctcatt actttttatt ctattatctc atttttggga aatttaggga gtttttagag
     1141 gtccccttat ataattaaac aactaaatgg ttgtcaattc tcaaggctag catcctctac
     1201 agatgttatt ccttggctct aaaacacata ccaacatagt ctagccactg aaatagcttc
     1261 tatcaccaaa ttatcttgtc aaacttgtca aaatcagctg attcacacgc tcttgtccaa
     1321 tctgattgaa atgcaatcca tcattggtat actgatagtc aagcatcgcc tctttttcaa
     1381 caacttcatt tagatcaatc actgaaatac ccagttcact tgctgactga acaataacgt
     1441 cattcagctg cacaatttct tcatttgaaa cgctatcacg aaacagcgtg taggcaatcg
     1501 tcgtcacaaa aacctgctct gctttggaaa caagactttc catcagctgg cgaatagtat
     1561 cctcaatcat atgcaaggga tagtcagtaa tcaaatcatt cacaccaaga gaaagcaaaa
     1621 ctttctttat cggagtagcc aaaaagagac cttggttttc aagtgctgtc gaagctgtca
     1681 tcccaccgat gctgatatta tcgaaaccat ccagtaacaa ggctaacaga cgactatcgc
     1741 caatcacaag actatcatgg actcgttgct cacataaacg ctttaactct cttttataaa
     1801 atggtttgtt ttgttgctca cgacgctggt aatcaaagta aattcgacca ataacaccag
     1861 taaaatcaaa gtgatcatct acatcaatcg aatcttcctt cgtcatcaca taggccgctg
     1921 ttttttcaga aaaataagtt ttatccgcta aataagcctg cttagaagaa atataaatcg
     1981 ctccattagg atagtagagt gttttctcat cttgacgacg ataactgcca cctaatcctg
     2041 caatatcctt agcgaatccg ttttcgtcta aagttgaaaa caatgttgga gacttatcga
     2101 ctttggtaaa gctaacaacg tggtcagctt gacctttccc atataactcc atcgcctcct
     2161 tgacatgttt tcccgatctt aatggggacg taacttgcag gagaacaaat acttggtcat
     2221 cagaaaaatc ttgtaaaaaa tgttcgttca gttgaaaaga ggttgtaaaa tctgtcgcca
     2281 agtcagctgg acgcatgagg acttgaaccc cagttgtttc acaaatttcc ttgtaaacct
     2341 ctgaatcagt actgacatat atattttctt tcttaaaaca tccagactca atcgcagctc
     2401 gaatggtatg gaaaatcatc ggtacaccat ctaaaaataa catgttttta tttggtaaac
     2461 cttttgatcc tgaccgagca ggaatcagac aaattggttc catcaattca cctatttaat
     2521 ctttctagca ggtacaccaa cataggtccc tgactccgtc aacgatttca aaacaactgt
     2581 ccctgccccc aatgttgtat aaggtgcaat ctcgatacat tgaatcactg ttgaaccact
     2641 tccaatataa gtgccttctc cgatacggca caagccattt atggtcactc ctggagtaat
     2701 gttacaatgg gcctccaccg tggtatgatg ttccacaatg gcacccgtat tgatgataca
     2761 attgtcatag acataggaat cggctcctac aaaacttgaa aaacctatga aaacccctcg
     2821 tcccttgata ctatctgggg aaaaaatatt ggcttgctcg ctaatgatgt tgaacaaagc
     2881 atcataatga tctttggcaa gcaagtcaaa gatttccttg cgcttgacat tgtcacctat
     2941 agtgacgaag acagcatcta cttttccatc atccaaatag gttaggacat cttgcaaggg
     3001 accaaataca ggatagccac gatagtcact gatcggttta tcttcaaaat atccaatgag
     3061 ttcatatcga cttctatcca accaaggaag gacaccatct gaaaaggtac ccgctcctag
     3121 aaaggctact tttttcatca aactttctcc cctatctatc ataaaactct ttcatggttg
     3181 aggcctgtac agataaaaat tccttgatag ctcgataacc ttgtaaagca gaatcaggtt
     3241 gttcaaatgg attggtaaaa tctatcacat cacgtaattg ccccaaacca ccaacaatcg
     3301 cttccttaga agttccaaca tgtaccacac tcggtcctga caaacgtcca aattggcgat
     3361 ttccaatatt taaggtcgga acctgtaatg agggcacttc aatcaaacct gacgaagaat
     3421 tccctattaa accttgtgaa tgcttgacca aggaatggta ataacgagtt ggaagcgaag
     3481 taaagatgta agaatcagag tcttgtttta caaattcatg catcaattcc attatcttat
     3541 cggcatgtgt atccgaattg gatccaatta tcaaacactg gctaccatct tcttttagag
     3601 catctaataa ggcctgcgtt tgttcttcgg ctgtgttatc ctccaaggta acagggtgaa
     3661 agagtacaac atagtaatcc tcggcaaaat caattccaag ttccatcgcc aactcttctc
     3721 ttgtcaaaaa gtcttgtttt aaaacatttt caacacccat agctccgatg ttcagtacat
     3781 ggttgggatt ttctcctagt tgaatgacac gatttctaaa ttcatccgtt gatgtcagat
     3841 gaaggtgact catcttggta atggcatggc gaatcgactc atcaaaattt cccatggttt
     3901 tttcaccacc atgaatatgg caaataggaa tattataaag caacgcagca ttggcaactg
     3961 gtagcatctc atagcgatcc cccagaatca acaccaagtc atactggact tcttcaaaaa
     4021 gaaccgtgag ttgctctgtc aaggtcgcta aagatttgac gattgtctgc ttagacgtat
     4081 ccgtcaaatg caatggaatc cgcttgacaa tcctacgctt gtccgcttcg atgtctttga
     4141 ccgtcatccc atatttttct tctagatgca tggctgtcac tacaagatcc agctccattt
     4201 ctggatcatc ctgtagatag ctcaataagc gacgcataat cccatattcg gcacgagagc
     4261 ctgtcacaaa acaaattttt ttcatcctta ctccgcttac atttgatttt caaaagcact
     4321 atggcaaata ttttggtctt cctcaaaatc ctgctcactc acctgcccca agactttgta
     4381 ccattccatt ggcgaaattc catttcctgg tcttttgaca gtgatgtttt cttctgtaaa
     4441 gacttcgcct ttagcaattg cttttttggc aacaatagat tttctagcta caattttatt
     4501 tcgtacttca acttcttctg gctctttttc aaatttacca agagattgtt ccactatcct
     4561 cactcctttt accaaggctg ctaagatatc aggagtagca ctcgctttat gatctggtcc
     4621 ttccatttca ttgtccagag taaagtgctt ttcaatcaat tcagctccca ttgctgcagc
     4681 agcgatgggt acttctgaac caacactatg gtctgaatag ccaattgtta agtttggaaa
     4741 ttcttttttc aaggtatgca agacattcaa attcaaagca gggtaagggg ttggatactc
     4801 ggttgtacaa tgcaaaatcg aaatatcggt cgttccattt tcctgcaaaa tcttcaccgc
     4861 ttgatgaatt tcatccataa cagccatacc agttgaaaga ataactttct tagcttgacg
     4921 accaattttt tccaaatagg gaagattggt aatctcacca gatggaatct tataaacggg
     4981 catatctgtg ctaatcaaga agtccaatga ttcctcatca aaaggtgtcg aaaacacatc
     5041 aactcccttt tcaagacagt aatcacgcaa atcaagatac tcttcaaagc tcaattccaa
     5101 acgacgagtc atttcgagct gagaatctga ctctcctgtt gtaatttttt ggtattctgc
     5161 ctttggtgcg tattttgaaa tcaacaaatc tgccttaaat gtctgaaatt taacggcatc
     5221 cacaccacaa tcaacggcaa cttctaccat tttccgtgct agatgaacat caccgttgtg
     5281 attacaacca atttctgcaa taatataaac cattttattt cctttctaaa aatgactgta
     5341 aatcgctccc ataaagtctt gagggagcag cttggttttc cttaagtagt aaaagaacac
     5401 taataaagat cgctacttca cttctgatag ccgattagaa aaaatagccc tagatttctt
     5461 tcgaatagtc tcagggcttg ttgcttctaa agcctgcttc ttcacacgat cttcaataga
     5521 ttggtggaag tttaatctgc ttttctaccc aatttttagg gagatttacc tcatgacttc
     5581 tggcataagc agaggcgcat acgtccttta agaaacattc ccttctttat acttgattat
     5641 agcacaattt tcatggtaga gaatacttga actttgggta gatggcagtg atggtcaatt
     5701 cttatgagca cctctcattt gggacgtttt tatatgggga cctctaaaaa ctaattttct
     5761 aaaatttaaa atgtttgatt taacaaggct ttcgtaactc caaattcgca attttgggag
     5821 tttatagagg tgcccttatt tagaccgttt ttccctgaat gtattgaggg caactgttaa
     5881 ttcctttcta aaaatgtagg cataaacgac tagaaccgct attcctagtg accaacgaat
     5941 ccagattgaa ccgacaaata ctgtcatcaa gcctgtatag acgacaacaa gagcaattac
     6001 cttaacaaat gttgaaatcg caacttcatc gtaagcatac tttttcttag caacaaaata
     6061 atgcaagact agcaacaaca gataggaagc agtcgttgcc aaagcagcac cataaattcc
     6121 tatcgtcggt atcaaaacaa agttgactga aatatttagt acacctgcta taaaagtacc
     6181 aattggcaaa aactttgtat ttccactata aaactggata ttggctggaa aactataaag
     6241 aaatacaaag aacaccccga caataatcat gggaataaat cccatactga aacgatactc
     6301 agatccacct aacaacatcg ctaattcagg gtaaattgtt agaaatccaa aagtcacaaa
     6361 caggccaatc gccagatagt aacggacata actgagcaaa tctttatctg cacctctctt
     6421 tttctcaaaa taccacggac accataccgt attcaagctc gaaaacacaa tttgtaagat
     6481 agacgcaagt gtgtagccga aactgtatag ggctacatct gacagtgtta gcatcttgcc
     6541 gagcatgatt ctgtcaaatt gattgagtac attatgacct aatccatgaa aaataagagg
     6601 aatcgatata cttaaaccat accgaagata gtcctttcga aaatgaagcc caatcttctt
     6661 atagaaaaac aacaaggaca cacaagcaaa aacaccagtc gttgccgagt ttgccattac
     6721 acgagcgatg aaatcattct ccatcgaaaa gatgagaaat aaagataaag cagtgttgat
     6781 aacagcgctc agtaccgata ggagtaaagt ccacatggac tgctgccgct gcactaaata
     6841 ggtcgtaaaa aatccttgca caacactcat aaaactttgc aaaaagataa gcggaacgac
     6901 ccaatcaggc aaaccaaata ggagcgatag gggctgactg aggagaaaag atagcccaaa
     6961 aattggtaaa aagaaagcga tagaagagac catcaaggtg gatacgaaat catcaaattt
     7021 ctcgcggaag tgtacccatc ccgggccaaa agccccacct aactgtagac cgataaagag
     7081 accaactagc cccacccacg aattatacaa gctaaactgc ccatatactt cctgagaaat
     7141 gacacgagta tagatgggga gggtaatgaa ggctaatccc tgaacgagga tggttccaat
     7201 cgtatagacg agacctgaga caactattga ttttttagac atgaatcctc ctattctatc
     7261 ccctcacgca aaatatcatt ttttgaaaga agaggaaaag tgtcctttaa atacactttc
     7321 tcttcaaaac aatttaaaaa atctaaagca gacgaactat aggtcatacc gatatcaaaa
     7381 cggatactac ctgccatttc gaacaactca aacggaatac cttgaggcag aagcaccaca
     7441 gccttaccca gaaatgaata atcaacccca tctcgtgggt gcggttttat gtagattgta
     7501 tagtcttccc gataaggggc aagacctgct acataaatct ccaacaactc ctcttcggtc
     7561 acatgataat cccaagacaa gggctgggtc aataatagca atcgtttttg agaagactct
     7621 tcatccgcta ctatcgccct tgctccaaat atctgcagca gcgcttgcac cttctctggc
     7681 gatgcttgat caaataattg ctttctcgga acttctacaa agggtttata agcctcgtca
     7741 aattgtacga gcgacagatc attgacctca atggattgac aatagagact tgaaccaatc
     7801 aaatatgttg gtttaaaata ccattgataa aagagtcttt tccagacaga tgattgaatt
     7861 gactccaaat cgcacactct tttatccttg aaaaaattat aaccatcctc caaaagagaa
     7921 tagggaatcc gatgtttatt taaaaaatga ccgacttgac ggtgatcttg aaaaatgatc
     7981 acctcgtcat agctctgtaa caaggaaagg cgttcttttg tttttgatct agctatcaaa
     8041 gaatatagat caaatgaacg ctccgtctcc tcgattagat gaacatgctg ctgcagttgc
     8101 tccctgacat ctggaaaatg cccgatgata tcaacggaca tcaaactatc tctctcaacg
     8161 tccatcttta acaaggaaat caggatctga tacatcgtat ggcaaatata aattcgtctc
     8221 aatttttctc cttctacata cagactttaa ggataagtaa ccccttttta taacccctgt
     8281 acagcttcga taatgtactg attcactctt tcttgccctt catcattgaa atgcaaaaca
     8341 ttttctgagt ccccctgtaa gtacatattc atggcttctt ttatctgttc cccagtccgt
     8401 aacggtgagg tgacttgcag aagaacaaat atacaatctt cataaaatcc agattcgtaa
     8461 aaaagtgcgt actgacttca ttcgatggag tatgataagt agatagttct ttgggtctta
     8521 acaatacatt gatgcctctt gtctcgcaaa tccccttggg gacctctaaa aactaatttt
     8581 ctaaaattta agatgttgat ttaacaaggc tttcgtaact ccaaattcgc aattttggga
     8641 atttatagag gtgcccccct tatacatttc tgaatccgta ctgacataga tgtcttcttt
     8701 ctcaaaacaa cctgattcaa ttgccacatc aatcgtgtga aaaatcatgg gtttcccgtc
     8761 caaaaatagc atgtttttat tcggtaagcc tttcgaacca gatcgtgctg ggattaaaca
     8821 aacagttctc ttaaaaattc tccttgttca gttaataaat atagctttga aaataaaggg
     8881 ggatactggg gtttagaaac agataccact cctctctcgt caacctattt gaatttcttt
     8941 gtcggaatat taacatgcga atctgctaat aaacgaaatg gcatctgcta atctgaaatg
     9001 agtcattatc gttttccacg tactctcata aacagatcca ctttgtagaa aatatagcca
     9061 ccaaacaggc aaattagaaa ggtaaacaag ccgttccaca aattcaacga agatacctta
     9121 aattgcactg ctaaaaatgg tgcgactact gaaaaataca gcatctgggt caagtagata
     9181 tgataagaag caactcccaa ttttgacaac agtattgctg gaatcttctg tccatacttt
     9241 atcataaaaa atagcatagc atacgcaaat gggacgcata gaaaggaagt agacttccaa
     9301 ccataaaacc aggagaaggg ctctatagaa tgattcacaa aaatcagaat tgctccaata
     9361 atcccaaata gggtcgcaat gaaagtatct accttggaac gcacatcctg ctttgaaaga
     9421 aaaaaccaag ccctagaaca aaaagataac gaagtgatat tagtctatat atatatgccg
     9481 tgttcagcca tgttagcaaa tatggcatcc actgaaaagt ttactaaaaa acaagtaagc
     9541 aagcccaacc atttattttt ctcgaaaaga acatacaaaa ttggtaataa aaaaactacc
     9601 tgaatcaaca acggaacata gtaactccca actccctgga cccgattctc cagaaagtag
     9661 ccacaggaca aatgaacgga gcgatgaaga acctgaaaaa ggctttactc ctatcagatg
     9721 gttctcgaat agctcaataa aacattaaca gccatcacga tagcatagag acaaagcatg
     9781 tttatacttt cttttatacc actgctgaac ttgagcttta gcgtctcttg ttttgtattc
     9841 cacttattcg ttcgaaaata ggcagaaagc aacagaaaaa ttggaacagc catgtcaacg
     9901 aaatacggaa agataaacca ttgacgctgc tcaacagacc aatccagatg tgtaaaaata
     9961 acacaaagta ccatgataca tttaatcgta tcaaagagtg ctattctact atttgttgga
    10021 ttcattttaa tccccttttc tttcaaccat ttattacaac attcttaccg agtactactt
    10081 tcacttcttc tcaatctttc ttgaatttta tctttccccg ttttcagaaa gacactaaaa
    10141 ttaagatgaa gacaccctac caaataataa gcattcatta gtaaagcaag tcgcttattt
    10201 tgcttcaatt gtttatatac aattctaaat agcgtttgga gaagcttctt ttgctgtttg
    10261 ctcaaccaat gattatattt gcctaaaaac aaaacagcaa aggctaaaaa tgaacgataa
    10321 cactctagta agagctcttt atctcctcta ctttcataga agtccattcg ttcattttga
    10381 aattccagta ggcaatggaa gcgatggtca gtcatactag aagttatgat actattttct
    10441 cggtcaacat aatagtacaa gcactcctta actattgcaa ctttttctaa ctcatagagc
    10501 aagcgataag tgaagtattc atcttcatga atcttaccct tttcaaatcg aaaatcttca
    10561 aatagttctt ttttatagag tttattccag gccaccacaa agcgatgacc atccgcctct
    10621 agcagctttt tacaaacatt cctgccgctc agaacagcct gatttgtagg aagcggctct
    10681 gctgttaaga aatgccccga agcatctacc ctatcataac cagcaactgc cacaagggca
    10741 ttctctctct caattgcttc gtgtaaacgt tggatgaact ccgaatgaat aaaatcatct
    10801 gagtctataa aagctaagta gtcacccttg gcgcgactta tgccataatt acgggcatct
    10861 gatagcccgc cgttctcttt tttaaaataa cgaatgcgac tatctttctt cgcatatgct
    10921 aaacaaattt cttccgaatt atccgtacta ccgtcattca ccagaagaat ctctatatgt
    10981 ttgtaggtct gatttacaat gctatttata cacttggata gatattgttc aacattgtaa
    11041 attgggacga tgatagaaat gtt
//
LOCUS       DBNFCO010000059        10886 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.059, whole genome shotgun sequence.
ACCESSION   DBNFCO010000059 DBNFCO010000000
VERSION     DBNFCO010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10886)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10886)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10886
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.059"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            15..1052
                     /locus_tag="AC1PIV_001462"
     CDS             15..1052
                     /locus_tag="AC1PIV_001462"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HIP6612477.1"
                     /translation="MKEGDLLFTPISEKIDINQVREHSKLSPETLAKKQARDRELEAI
                     LKGEDNRLLLVIGPCSSDNEEAVLDYAHRLAKLQEEVKDKIFMVMRVYTAKPRTNGDG
                     YKGLMHQPDTDAAPSLINGIKAVRNLHYRVITETGLTTADEMLYPENLPLVDDLVSYI
                     AIGARSVENQQHRFVASGIDVPTGLKNPTSGNLKVMFNGLFAAQKKQSFLFNNTEVET
                     SGNPLAHVILRGAVNENGKYLPNYYYDNLLETIELYDQFGLKNPFIIIDTNHDNSGKN
                     YLEQIRIVRQTLINRDWNESIRNYVRGFMIESYIEDGRQDNPDVYGKSITDPCLGWEK
                     TQELIREIYNR"
     gene            1062..2087
                     /locus_tag="AC1PIV_001463"
     CDS             1062..2087
                     /locus_tag="AC1PIV_001463"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HIP6612478.1"
                     /translation="MGIHKRSTSLDIDKVKELSKLEGEFLAAKNQRDEELKRIIRGED
                     DRLLLVIGPCSSDNEEAVLEYARRLSKLQEEVKDKIFMVMRVYTAKPRTNGEGYKGLV
                     HQPDTSKLPDLINGIAAVRNLHYRVITETGLTTADEMLYSANYPLVEDLVSYHAIGAR
                     SVEDQEHRFVASGVDMPTGMKNPTSGNLTVMFNGIYAAQNKQNFIYRDAEVDTDGNPL
                     AHAILRGANTEKGGYEPNYYYDILLKTIKQYEQFGLKNPFIVIDTNHDNSGKNYLEQI
                     RIVRQTLINRDWNEAIRKYVRGFMIESYLEDGRQDSPEVFGKSITDPCLGWEKTEALI
                     REIHQTV"
     gene            2133..3002
                     /locus_tag="AC1PIV_001464"
     CDS             2133..3002
                     /locus_tag="AC1PIV_001464"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HIP6612479.1"
                     /translation="MNIDGYTRLAAVVAKPIKHSISPFIHNLAFKETGVNGVYVAWEI
                     PEEDLAVTLENIKRYDMFGINLSMPYKQAVIPYLDSLTDSARLIGAVNTVIHQDGLLI
                     GHNTDGIGFFKSLEKLRGFQVRNKRLTILGGGGASTAIIAQATLDGAKEITIFCRQQS
                     LERTQASLTPIARATGVPMQILALDDSQLLQEHITNSDLLVNGTSVGMDGYSQPVPST
                     IRFPENLLVADVIYQPFETPLLKLAQSQGNPTINGLGMLLFQAAEAFQSWTGQEMPTD
                     LIWDQLVQKYDIK"
     gene            3015..4082
                     /gene="aroB"
                     /locus_tag="AC1PIV_001465"
     CDS             3015..4082
                     /gene="aroB"
                     /locus_tag="AC1PIV_001465"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HIP6612480.1"
                     /translation="MKLTVNLPNTPYDILIQRGSLAQTGAWVKELWKPQKIAIITDDH
                     VGSLYRETVQSSLEQAGFETIVFEFPEGEASKNLDTVNQAYEFLVKNGMTRSDGIIAL
                     GGGVVGDLAGFVASTYMRGIHFLQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFCQP
                     DGVLIDPDTLKTLGKRELIEGMGEVVKYGLIDDVELWETLDQLDGSVESILEHADYII
                     YHSCEVKRKVVVEDELDNGVRLYLNFGHTIGHAIEATAGYGQVMHGEAVAIGMVQISR
                     AAEKKGLMPAGMTAKIIAMCEKFGLPTTHQPWNVDELYASLTHDKKTRGKTIKLVIVP
                     QLGQAAIHQIPMEEMLEFLQV"
     gene            complement(4287..5087)
                     /locus_tag="AC1PIV_001466"
     CDS             complement(4287..5087)
                     /locus_tag="AC1PIV_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIP6612481.1"
                     /translation="MSTILSIQNIHKTFEAGTVNENHVLRGLNLDVKEGDFISIIGGN
                     GAGKSTFMNSLAGALTVDSGDILLEGKSIKYVSAAKRSKDISRVFQDPKMGTASRLTI
                     EENMAIAYRRGLSRGLGWGVKDSERAIFKEALKELGLGLENRMKVDTQFLSGGQRQAL
                     TLMMASLVKPKVLLLDEHTAALDPKTSDMVMELTKKIVESHQLTALMITHNMENAIEY
                     GNRLVMLHRGQIVVDVEGEEKKNLTVQNLMDLFYKNSGEKLTDDEMIL"
     gene            complement(5097..5990)
                     /locus_tag="AC1PIV_001467"
     CDS             complement(5097..5990)
                     /locus_tag="AC1PIV_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIP6612482.1"
                     /translation="MDIILSSISQGLLWSVMAIGVYLTFRILDIADMTAEGSYPLGAA
                     VCATGIVNGVNPLLATFMAMVAGMGAGLISGLLHTKLKIPALLTGIVTLTGLYSINLK
                     ILGKANVALLKQETLVTQLQDFGLTKTNAVLVIGLVFVLAVVGLLTLLLNTQIGLAIR
                     STGDNIPMSEANGINVDNMKIYGYMLSNGLIALCGALLTQNNGYADLNSGTGTIVIGL
                     ASVIIAEVILRNLRLGWRLLSVVLGAVVYRLIILAILEIPGMDADLVKLFSAILLATV
                     LYVPELQKKLNIRRPKLNGNA"
     gene            complement(6045..7019)
                     /locus_tag="AC1PIV_001468"
     CDS             complement(6045..7019)
                     /locus_tag="AC1PIV_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HIP6612483.1"
                     /translation="MYYKLVKKLATISVASMGLLTLAACSSSSEQASSDVVKVGVLQY
                     MEHESLTAAREGFVAELEANGYKEGEKLVLDYQNAQGDQANLQTISEQLIDGNDIVLA
                     IATPSAQSLATVSTETPIVFTAVTDPLSADLVESIEKPGGLLTGTSDQAPIDKQVELL
                     GQAVPDAKTVGILYTTSERNSEVQVEQAKELLEKAGYKVVVKGITSSNEVQDATTSLM
                     KDVDALFIPTDNTVASTMTMIGELSVEHKVPVIGGSTDMVDEGGLLTYGTNYEALGRQ
                     TAKMAIKIIEGANVSETAVEYPETVSLHVNEEMAQKLGIDTSKLAVSE"
     gene            complement(7043..8002)
                     /locus_tag="AC1PIV_001469"
     CDS             complement(7043..8002)
                     /locus_tag="AC1PIV_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HIP6612484.1"
                     /translation="MGFKKIILSSVALLSAVTLAACSSNSSDSSSVNVGIIQYAEHEA
                     LSSAREGFVEALEEAGYKEGENLTIDLQNAQGDQANLQTMVEKLAGKNDLNFAIATPA
                     AQTMLNADSETSSVFTAVTDPVEAGLVESLEKPGGTMTGSIDATDVEGQIEMLLKVVP
                     TAKTVGIFYNSSEVNSEVQAEQAKKALEAKGVKVEVTTVTTTNDVQQAITSLAGKVDA
                     IYLPTDNTVASTASTIGDILKEAKVPAMGSDAAVIDAALFTYGVDYHAIGVQAGELAV
                     KILKGEKPADLAVEKPNTAAITVNEEMAKAVGIDAATIKALEE"
     gene            complement(8717..9718)
                     /gene="lacD"
                     /locus_tag="AC1PIV_001470"
     CDS             complement(8717..9718)
                     /gene="lacD"
                     /locus_tag="AC1PIV_001470"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HIP6612485.1"
                     /translation="MTKLQLSQAKFNHMTRLSNSDQVIAALAIDQRGALKRLLAAAAG
                     GGEFGDDILIDFKKVISSDLTPYASSILLDAEYGVPASELRHADCGFIAAYEKTGYDA
                     STPGRLPDLLPNWSAKRIKELGADAVKILLYYDVDDKPEINDIKHAWVERIGSECIAE
                     DIPYFVEILTYDASDMDVTSREYAALKPHKVNGAMREFSKSRYNADVLKVEVPVNMNF
                     VEGYTDEEPVYTVEEAKAFFKEQTDSTHLPFIYLSAGVSAKLFQETLVFAKEAGSSFN
                     GVLCGRATWKDAVAIFASEGEEAAKAWLADQGRRNVEELNEVLAITARPWTEKVEVK"
     gene            complement(9741..>10886)
                     /gene="nagA"
                     /locus_tag="AC1PIV_001471"
     CDS             complement(9741..>10886)
                     /gene="nagA"
                     /locus_tag="AC1PIV_001471"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HIP6612486.1"
                     /translation="MTVFIKAKSIILPESEVESAYLEITDKGQFGRIVIEKPEGEIVD
                     YSDFHLAPGLVDTHIHGYASHDVMDNDFEGIKVISEGLLSCGVTSWLPTTLTDTTENL
                     DAVCETIGTYAGQETGAKIQGIFLEGPFFTEKYKGAQNPKYMSDPSIEKLDNWHSLSK
                     GLVNKIAIAPEREGVKEFIEFANSKAIHTALAHSDATYAQAEAAVEAGANIFVHVYNG
                     MSGLHHREPGMVGAALNLKNVYAEMICDGHHVHPAAAEIVVKARGAEETVLITDCMRA
                     GGMGEGESRLGEFEVVVKDGTARLKESGSLAGSILELIEAVQNVVKWGLVSLPDALRM
                     ASLAPARSVNIDHICGRIAEGRAADFIVVDDAGRLQATYLDGVKRFG"
BASE COUNT         3215 a         2513 c         2069 g         3089 t
ORIGIN      
        1 tgaggaacct ataaatgaaa gagggagatc tattgtttac accaatcagc gaaaaaattg
       61 acatcaatca agtacgagaa cattcaaaac tttctccaga aacacttgct aaaaaacaag
      121 ctcgtgaccg tgaacttgaa gccatcttaa aaggtgaaga taatcgtctt ctcctagtaa
      181 ttggaccatg ttcttctgac aatgaagagg ctgtcttaga ttatgctcac cgcttggcca
      241 aactccaaga agaggtcaaa gataaaattt tcatggtcat gcgcgtctat actgccaagc
      301 cacgtaccaa tggtgatggt tataaaggac tcatgcacca accagataca gatgctgcac
      361 caagcctcat caacggaatc aaagcagttc gtaacctcca ctatcgtgtc attacggaaa
      421 caggtttaac tactgctgac gagatgctct accctgaaaa cctgcctttg gttgatgact
      481 tggtttccta catcgctatc ggagctcgtt cggttgaaaa tcagcagcac cgctttgtag
      541 cgtcaggcat cgatgttcca acaggcttga aaaatccaac gtctggtaac ctcaaagtca
      601 tgttcaacgg tctttttgct gctcagaaga aacaatcctt cctcttcaac aatactgaag
      661 ttgaaacatc tggcaatcca cttgctcacg ttattcttcg tggcgcagtc aatgaaaatg
      721 gtaaatacct accaaactat tactacgaca atctcttgga aaccattgag ctctatgacc
      781 aatttggttt gaaaaatcca ttcatcatca tcgataccaa ccatgacaat tctgggaaaa
      841 attatttgga acaaatccgt atcgtccgtc aaaccttaat caaccgtgac tggaacgaat
      901 ccattcgtaa ctacgttcgc ggattcatga ttgaatccta cattgaagac ggtcgccaag
      961 acaatccaga tgtctatgga aaatccatca cagacccttg cttaggctgg gaaaaaacac
     1021 aagaactcat ccgagaaatt tacaacagat aggaagatac tatgggaatt cacaaacgta
     1081 gcaccagttt agacatcgat aaagtaaagg aactttccaa gttagaagga gaatttctag
     1141 ctgcaaaaaa tcagcgcgat gaagaactga aaagaattat ccgaggcgaa gatgaccgtc
     1201 tgctcttggt tatcggtcct tgctcatcag ataatgaaga ggccgtccta gaatatgcac
     1261 gtcgtctctc taagcttcaa gaggaagtca aagataaaat cttcatggtc atgcgggttt
     1321 acacagctaa gccacgtacc aatggggaag gctataaagg actggttcat cagccagata
     1381 cttctaaatt accagacctc attaacggaa ttgcagccgt tcgtaatttg cattaccgtg
     1441 tcattactga gactggactc acaactgctg atgaaatgct ctactctgcc aactaccctc
     1501 ttgtggaaga cttggtgtcc taccatgcta tcggagcacg ttcggttgaa gaccaagaac
     1561 atagatttgt tgcatcaggt gtcgacatgc caactggtat gaaaaaccca acttccggta
     1621 atttgaccgt tatgttcaat ggtatctacg ccgcacaaaa caaacagaac tttatttacc
     1681 gtgatgcaga agttgataca gatggcaacc ctctagctca tgctatcctt cgtggtgcca
     1741 atactgaaaa gggcggttat gagccaaact actactatga tattctcttg aaaaccatca
     1801 aacagtatga acaatttggt cttaaaaatc catttatcgt aattgatacc aaccatgata
     1861 attctggaaa aaattacctg gagcaaatcc gtatcgtccg tcaaaccctc atcaaccgtg
     1921 attggaatga agctattcgc aagtacgttc gtggtttcat gattgaatcc tacttggaag
     1981 acggccgtca agatagccct gaggtattcg gcaaatccat taccgatcct tgcttaggct
     2041 gggaaaaaac ggaagctctg attcgtgaaa ttcatcaaac cgtctaattc tttccttaat
     2101 tttttatacg ataaataatt tggaggtaag ctatgaacat tgatggttac actcgtcttg
     2161 ctgccgttgt tgcaaagcca atcaaacact ccatttcccc cttcattcat aatctggctt
     2221 ttaaggaaac aggtgtaaat ggtgtctatg tcgcttggga aattcccgag gaagatttgg
     2281 ctgtaacgct tgaaaatatc aaacgatatg atatgtttgg tatcaacctg tccatgccct
     2341 ataagcaggc tgtcatccct tatctcgata gcctgactga ctctgctcgc ttgattggcg
     2401 ctgtcaatac cgtcattcat caggatggct tactaatcgg tcataatacc gatggcattg
     2461 gattcttcaa aagtttagaa aaactaagag gattccaagt acgcaacaag cgactaacca
     2521 tcctaggtgg tggtggtgct tctactgcta tcatagctca ggctacattg gatggtgcaa
     2581 aggaaattac cattttctgc cgtcaacaaa gcttggaaag aacacaggcg agtcttacac
     2641 ctattgctcg agcaactgga gttcccatgc agatcctagc gcttgatgat agccaattac
     2701 tacaggaaca tatcaccaac tccgacttac tagtcaacgg aaccagtgta ggcatggatg
     2761 ggtattctca acctgttcct tctaccattc gctttcccga aaatcttttg gttgcggatg
     2821 tgatttatca accattcgaa acacctttat taaaactagc ccaatcacaa ggcaatccaa
     2881 ctatcaacgg tttgggcatg ctccttttcc aagcagctga agccttccaa tcctggactg
     2941 gacaggaaat gccgactgac ttgatttggg accaattagt ccagaaatat gacatcaaat
     3001 agagaggaaa tctgatgaaa ctgaccgtca atcttcccaa cactccctac gacatcctta
     3061 tccaaagagg aagtttagca cagacaggtg catgggtcaa agaactttgg aaacctcaga
     3121 aaatcgccat tattacagat gaccacgttg gctcactcta ccgcgaaaca gttcagtcaa
     3181 gcttagaaca agctggtttt gaaaccattg tttttgaatt tccagaaggt gaagcctcaa
     3241 aaaatcttga tactgtcaac caggcctacg aatttctcgt aaaaaatggt atgacacgaa
     3301 gtgatggaat cattgctctc ggcgggggag tcgttggcga tttggcaggt tttgtcgctt
     3361 ctacctatat gcgtggtatc catttcctac aaattccaac cagcctaact gcccaagtcg
     3421 attcttctat cgggggaaaa actggcgtga acaccccatt tgccaaaaat atggtgggga
     3481 ccttctgcca gccagacggc gttctcattg accctgatac cctaaaaaca ctcggcaaac
     3541 gagaattgat tgaaggaatg ggcgaggttg tcaaatatgg cttaatagat gatgtggagc
     3601 tctgggaaac cctagaccaa ttagacggct ctgtcgagag cattctggag catgctgact
     3661 atattatcta ccactcctgt gaagtcaaac gcaaggttgt tgtcgaagat gaattagaca
     3721 acggtgtcag actctatctc aacttcggtc acacgattgg acatgctatt gaagcgaccg
     3781 ctggctacgg ccaggtcatg cacggtgaag ctgttgccat cggtatggta caaatctcac
     3841 gcgcagctga gaaaaaagga ctgatgccag ctggtatgac agcaaagatt atcgccatgt
     3901 gtgaaaaatt cggcttgccg actacacacc agccttggaa tgtagatgaa ttatacgcct
     3961 ccctaactca cgataaaaaa acacgtggca agaccatcaa acttgtcatc gttcctcaat
     4021 tgggacaggc tgccatccat caaattccaa tggaagaaat gctagaattt ctacaagtat
     4081 agtcatttag ttgactttta cgtcgaagta ataaaagtca actaatactc aatgaaaatc
     4141 aaaaacagac taggcgacgc agatgcagat agaactgaag ttcatcaaat taagtcaaca
     4201 acgtctgatt ttgattttcg aagagtataa atgacgatat aagaaaaaag actactgact
     4261 tgcatgaaat cagtagtctt atttttttat aaaatcatct catcgtcagt tagcttttca
     4321 ccgctgtttt tgtagaaaag gtccatcaag ttttgaacag tcaagttctt cttctcttct
     4381 ccttctacat cgacaacaat ctgaccacgg tgcaacatga ccaaacgatt accatattca
     4441 atggcgtttt ccatattatg cgtaatcatc agagctgtca actgatgact ttccacgatt
     4501 ttcttggtca attccataac catatcgctg gtttttggat caagggccgc agtgtgttcg
     4561 tccaggagca gaacttttgg tttaaccagc gaagccatca tcaaggtcag agcctgacgt
     4621 tgaccacctg aaagaaattg cgtgtccacc ttcatacggt tttctagtcc cagaccgagc
     4681 tctttcaagg cttccttaaa aatagcacgt tcactatctt tgacccccca gccaagacca
     4741 cgtgacaatc cacgacgata ggcaatagcc atattttctt caatggtcaa gcgagaagct
     4801 gttcccatct taggatcttg gaaaacacgg ctgatgtcct tagagcgttt ggcagctgag
     4861 acatacttaa tggatttacc ttcaagcaaa atatcgcccg aatcaaccgt caaggcacct
     4921 gcaagtgagt tcatgaaagt tgatttacca gcaccattac caccgatgat agagataaaa
     4981 tcaccttctt ttacatctaa gttcaaccca cgaaggacat ggttctcatt aactgttcca
     5041 gcttcgaagg ttttatgaat attttggatt gataaaattg tagacatgac ttcctcctaa
     5101 gcatttccat tcaattttgg acgacgaata ttcaatttct tctgcaattc tggcacatag
     5161 agaacggttg ccagaaggat agctgagaag agtttaacaa ggtctgcatc catacctgga
     5221 atttccaaaa tcgctaagat aatcaaacgg taaacaactg caccgagaac aaccgatagg
     5281 agtctccaac ccaagcgtaa gttacgcaag ataacttctg caataatgac agatgctaga
     5341 ccgataacaa tggtacctgt accagagttc aaatccgcat agccattatt ctgagtaaga
     5401 agagcaccac aaagggcaat tagaccattc gacaacatat aaccgtagat tttcatatta
     5461 tctacattga taccattggc ctcactcatt ggaatattat cccctgttga acgaatagct
     5521 agaccaattt gtgtattgag caagagcgtc aataagccta caactgctag tacaaagacc
     5581 agaccaatca ccaaaacagc atttgttttt gtcaaaccaa aatcctgcaa ttgggtcact
     5641 agagtttctt gcttaagcag agccacattg gctttgccta agattttcaa gttgatggag
     5701 tagagtcctg tcaaggtaac aataccggtc aaaagggctg gaatttttag ttttgtatga
     5761 agtaaaccag aaatcaagcc tgcacccata ccagctacca tagccataaa ggttgccagc
     5821 aagggattca ctccgttcac aatccctgtc gcacaaacag cagctccaag cggataagat
     5881 ccctcagctg tcatatcagc aatatctaaa atacgaaacg tcaagtaaac accaatcgcc
     5941 ataactgacc aaagcaagcc ttgcgagata cttgataaaa taatatccac gattttctcc
     6001 tttttctaaa ttcgtagtca atactaggtt ctatcttacc gatcttattc agatacagca
     6061 agcttagaag tatcgatacc taatttctga gccatttctt cattaacgtg aagactgacg
     6121 gtctctgggt attctactgc cgtttctgac acattggctc cttcgataat cttaatagcc
     6181 atttttgcag tttgacgacc taaagcttca tagttggtac cgtaagtcaa aagacctcct
     6241 tcatccacca tgtccgttga accaccgatt actggaacct tatgctccac agataattca
     6301 ccaatcatgg tcatggttga agcgacagta ttgtctgttg gaataaagag agcatctaca
     6361 tccttcatca agctagttgt cgcatcttgg acttcatttg aagatgtgat tccttttact
     6421 actaccttat aacctgcttt ttctagcaat tccttagctt gctctacctg gacttctgaa
     6481 ttccgttcgc tagtagtgta caaaatacca acggtcttag catcaggaac agcttgtcct
     6541 agcaattcaa cctgtttgtc aattggagct tgatcagatg tacctgtcaa aagtccacct
     6601 ggtttttcaa tggattctac caagtcagct gacaagggat ctgtaaccgc agtaaagaca
     6661 atcggcgttt cagtagacac agtcgctaaa ctctgggcag acggcgtagc gattgccaag
     6721 acaatatcat ttccatcgat taattgttct gaaatggttt gaaggttagc ttgatcgcct
     6781 tgggcatttt gataatccaa aaccaatttt tcaccctctt tataaccatt tgcttctaat
     6841 tccgccacaa aaccctcacg ggcagctgtc aatgattcat gctccatata ttggagaact
     6901 ccaactttta ccacatctga ggaagcttgt tctgatgatg aggaacaagc tgcaagtgtt
     6961 agcaaaccca tacttgctac tgaaatagtt gccaattttt ttactagctt ataatacata
     7021 aacgtttctt ctcctaaata ttttactctt ctaatgcttt tatagtcgct gcatcaatac
     7081 caacagcttt agccatttct tcattgacgg taatagccgc tgtatttggt ttttcaactg
     7141 ctaagtcagc aggcttttca cccttcaaaa tcttcacagc caattcacca gcttgaacac
     7201 cgatagcatg gtagtcgaca ccgtaggtaa atagagctgc gtcaataact gccgcgtcac
     7261 ttcccatagc tggaactttt gcttctttta aaatatcacc gattgttgaa gctgtagagg
     7321 caactgtatt atcagttgga agatagatag catcgacttt tcctgcaagt gaagtaatag
     7381 cttgctgaac atcgtttgtc gtcgtaactg ttgtcacttc tacttttaca ccttttgctt
     7441 cgagtgcttt tttagcctgc tcagcttgaa cttctgagtt tacctcgcta gaattgtaga
     7501 aaataccgac agtcttcgca gttggtacaa ctttgagcaa catctcgatt tgaccttcca
     7561 catcagttgc atcaatcgat cccgtcatgg tcccacctgg tttttccaat gattcaacca
     7621 aacctgcttc aactggatct gtgacagctg tgaatacact tgatgtttca ctatctgcat
     7681 taagcatggt ttgggctgcc ggtgttgcga tggcaaagtt aagatcattt tttcctgcca
     7741 atttctcaac cattgtctgt aagtttgctt gatcaccttg agcattttgc aaatcaatcg
     7801 tcagattttc accttccttg tagcctgctt cttcgagcgc ctctacaaag ccttcacgag
     7861 ctgagctcaa cgcttcatgt tcagcatatt gaataatacc aacattgact gaacttgaat
     7921 ctgacgaatt ggaactacat gcagcaagcg ttactgctga caaaagtgct actgaactaa
     7981 gtataatttt tttaaatccc atgattattc tccttttata aatataatag caaacaagaa
     8041 aggaccgctt agactacact ctaaacggtc cttatatttc atctgtatag gaaaacagaa
     8101 tgaattatcc gtgccattta gatgtatcat ctatgaggca catgtcaaaa tagctacagc
     8161 cacatagata caaactttac gttcccgtgt ttgcatccat gtttaccatg tctacaaaca
     8221 ctatctaaaa tagccgtaga aataagtatg attagctgaa tgattttgac acatttgtaa
     8281 catctctgtt tccctttctc atttatttgt aactatcata actgttttca aattatttgt
     8341 caatagggaa ttgcgtaaat tttcagattt ttcaagtttt ttcgaatttt tctaaaaata
     8401 gacccctata ttattagcta taaaacgacc tgtcatcttg tttatatagc cttttagttt
     8461 acttttagta cttgctccaa ctatttcaca aatagtcaga ggttggaaat aaggggaaca
     8521 aggtttgcgt caacaaccgc agctataact gtttctggga ttgcttgcac agtaaatgga
     8581 ctgttcaagg tgagagatat aagagcggat tgcaaaacca ggtcaacatc gactgatttt
     8641 gattttcgaa gagtataaat gactatattt gatgttacaa aaagtctgaa cctaagccca
     8701 gaccctacta aaacaattat tttacttcaa ctttttcagt ccaaggacgc gctgtaattg
     8761 ctagaacctc gtttagttct tctacgttgc ggcggccttg atccgccaac caagctttgg
     8821 ctgcttcttc accctcgctt gcaaagatgg ctactgcatc cttccaagtc gcccgaccac
     8881 aaagaacacc attaaagctt gaaccagctt ctttggcaaa gacaagggtt tcttggaaaa
     8941 gtttagcaga tacgccagcg ctcaaataaa tgaatggcaa gtgagtgcta tctgtttgtt
     9001 ccttgaagaa ggccttagct tcctcaactg tatagactgg ctcttcatct gtgtaacctt
     9061 ctacaaagtt catattgaca ggtacttcaa ccttgagcac gtcggcatta taacgtgact
     9121 tactaaattc acgcatggca ccattgacct tgtgtggttt gagggctgcg tattcacgag
     9181 aagtcacatc catatcgctg gcatcgtaag tcaagatttc gacgaagtaa ggaatatctt
     9241 ctgcgataca ctcactacca atgcgttcta cccaagcatg cttaatgtcg ttgatttctg
     9301 gcttgtcatc tacatcatag taaagcaaga tttttacggc atctgcaccc aattctttga
     9361 tacgtttggc tgaccaattt ggcaaaaggt ctggcaaacg acctggtgta gacgcatcgt
     9421 aacctgtttt ttcataagct gcaatgaaac cgcaatctgc atggcgcaat tctgaagccg
     9481 gaacgccgta ttccgcatcc aagagaatgg agcttgcata aggagtcaaa tcgcttgaga
     9541 tgactttctt gaagtcaatc aaaatgtcat ctccaaattc gccaccacct gctgcagcag
     9601 caagcaagcg tttcaaagcc ccccgttggt caatcgccaa agccgcaatc acctgatcgc
     9661 tgtttgacaa gcgagtcatg tgattgaatt tagcctgaga aagttgtaat tttgtcatta
     9721 gtttcctcct aaggatttta ttaaccaaat cgtttcacgc catctagata ggtcgcttgt
     9781 aagcgtcctg catcatctac gacgataaag tctgcagctc ggccttctgc aatccgacca
     9841 caaatatggt caatattgac agagcgagct ggtgccagag aagccatacg aagggcatca
     9901 ggtagggata ccaagcccca tttcacaaca ttctgcactg cttcaatcaa ttctaagata
     9961 gaacctgcca aactaccact ttcttttaaa cgagcagttc catcttttac aacaacttca
    10021 aattcaccga ggcgggactc cccttcaccc ataccgccag ctcgcataca gtccgtaatc
    10081 aaaacagttt cctcagctcc acgtgctttg accacgattt ctgccgcagc tggatgaaca
    10141 tggtgtccat cacaaatcat ttccgcatag acatttttta aattcaaagc agcaccgacc
    10201 atacctggtt cacggtgatg aagcccactc atcccattgt aaacatggac gaagatattg
    10261 gcaccagctt ctactgccgc ttccgcttgc gcataggtcg catcgctgtg agccaaggca
    10321 gtatgaattg ccttgctgtt agcaaactcg atgaattctt tgacgccttc acgttctgga
    10381 gcaatagcaa ttttattgac taaaccttta gataagctgt gccaattgtc taacttttca
    10441 atggatggat cgctcatgta cttaggattt tgtgctccct tgtatttttc tgtaaagaaa
    10501 ggaccttcta agaaaatacc ttgaatcttg gcgcctgttt cctgccctgc ataagtccca
    10561 atcgtttcac aaactgcatc taaattttca gtcgtatctg ttaatgtcgt tggaagccaa
    10621 gaggtcaccc cacaagacaa gagaccttct gaaattacct tgatcccttc aaaatcattg
    10681 tccataacat cgtgagaagc gtagccgtgg atatgtgtat caactagccc tggtgctaaa
    10741 tgaaagtcag aataatcaac aatctcccct tcaggctttt caatcacaat ccgtccaaac
    10801 tgacccttgt cagtaatttc caaataggct gattcgacct cactctctgg taaaataata
    10861 gattttgctt ttataaatac tgtcat
//
LOCUS       DBNFCO010000060        10533 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.060, whole genome shotgun sequence.
ACCESSION   DBNFCO010000060 DBNFCO010000000
VERSION     DBNFCO010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10533)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10533)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10533
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.060"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            364..651
                     /locus_tag="AC1PIV_001472"
                     /pseudo
     CDS             364..651
                     /locus_tag="AC1PIV_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(1175..1813)
                     /locus_tag="AC1PIV_001473"
     CDS             complement(1175..1813)
                     /locus_tag="AC1PIV_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HIP6612487.1"
                     /translation="MIIHKSVNPVAFQNTYYLENDTHLIIIDPGSDWTKIQVTIEKIG
                     KPISAILLTHTHYDHIMSLDILRETYNFPPVYVAENEASWLYTPEMNLSGLPRHDDME
                     NVVCRPAEKIFQYQEDYQFDGFHFKVVPTPGHSIGGVSFIFPEDECVITGDALFRETV
                     GRTDLPTSNFDDLITGIREHIFTLPNHYTVHPGHGQNTSVGHEKNFNPFFRM"
     gene            1921..4389
                     /locus_tag="AC1PIV_001474"
     CDS             1921..4389
                     /locus_tag="AC1PIV_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HIP6612488.1"
                     /translation="MNSMKDTRTSNRYAVVDLEATGTGTDAKIIQIGIVLVENGEIID
                     SYATDINPYELLDDHIKNLTGITDQQLSQAPDFGQVASTIYDMIGDAIFVAHNVKFDA
                     NLLAEALFFEGYELLTPRVDTVELSQLFFPTFEKYSLGNLAEHLELGLDQAHTAISDA
                     MATARLLIKIQEKIKSLPRSIVEKILDLADNLLFESRLVIDEMVPVLSENLSYDLESI
                     HDLVLKKPEEIKSAYRLSEDFSTNIALLGLHERKKQTAFAQVVEKRLVDEEKVHFIQA
                     QAGLGKTYGYLLPLLAKSDQPLLVTVPTKLLQEQIMEKEGSKLKEIFRIPIVSLKSPK
                     HFIKLDNYWKTLQRQDDNRLVNQFKMQVLVWLCETTTGDLDELKQKQRYQAYFDEIAH
                     DGKLEPESLFWGLDFWQRLNQQALSSRLLITNHAYFLSHLKDQDPHMDKRMVVIDEAQ
                     KFLLAAENLATASQDLTSMLQVLQSKKDRATAILDQRLYESCQFELNHFLSRFRQHGQ
                     REVQKAELHQLGQNLEELGDVDLNDLHQLIDYYDTFWLEEKNLEEKRLAYLRSSKDSL
                     LNATNYLPDTKIFCISATLTISKKVSLADLLGFEQVTLDLIPTQTVTNQRLLFPTHLP
                     DILAWTKEEHAAYLATTLGEIAELGRPILVLFTSISMLLQVSDLLEDNNIPHLAQHKH
                     GQEMTLKRKFERGECQILLGTGVFWEGVDFASQNQLIQVITRLPFDNPKDRFVQKINH
                     HLREEGKNPFYDYSLPMMMIKLKQAIGRTNRHDKQDSLVLVLDPRVHTKRYGQQILSF
                     FEKDYLMLSVDAKEIEGAIQDFFE"
     gene            4549..5625
                     /gene="proB"
                     /locus_tag="AC1PIV_001475"
     CDS             4549..5625
                     /gene="proB"
                     /locus_tag="AC1PIV_001475"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HIP6612489.1"
                     /translation="MTEKTIVFKVGTSSLTQENGSLDRIKIARITNQLAQLHQKGYQI
                     VLVTSGSIAAGFRRLGFDKRPTKIAEKQASAAVGQGLLIEEYTQNLMKDGIVSAQILL
                     TQDDFADARRYQNASQALQVLLKQRAIPIINENDTIAIEEIKVGDNDTLSAQVASLLK
                     ADLLVLLTDVDGLYTANPNSDPTAQHLPQIKEITEDLFAMAAGAGSSNGTGGMTTKLQ
                     AAQIATKSGVPVFICSSKEDTALLQAVTQANRGTLFLADDHAMNQRKQWMAFYARTDA
                     AVEVDAGAVDAMLHQGRSLLATGVKALEGDFEVGQVVEVYSQADHRLIGKGRVKLSSK
                     DLQDQLANGRAEGVLIHRNDWVSL"
     gene            5690..6928
                     /locus_tag="AC1PIV_001476"
     CDS             5690..6928
                     /locus_tag="AC1PIV_001476"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HIP6612490.1"
                     /translation="MTTTQVLLDSLLANKASINLATTEQKNQALSAMADQLVAQTEAI
                     LAGNAIDMEHAQGKISQVMQDRLLLTEERIEAMADGIRALIGLPDPVGLVLEESTRAD
                     GLNICKKSIPFGLVGMIYESRPNVTSDAAALAIKSGNAVILRGGKEAFHSAKAIVTAL
                     KSGLEEAGVSPKVIELVQDTSRVSATELMTAKGKIDLLVPRGGAGLIQAVVENATVPV
                     IETGTGICHVYVDKDADLDKALRIVVNAKTSRPSVCNAAEVLLVHEEIASQFLPRLEE
                     ALSGQVELRADSQAQALLNQARPAGDQDFDTEFLDYIMAVKVVSSVEEAISHIAQHST
                     GHSEAIVTENSQTAEHFTLHVDSAAVYVNASTRFTDGGEFGLGCELGISTQKMHARGP
                     MGLREMTTYKYIITGDGHIR"
     gene            6938..7723
                     /gene="proC"
                     /locus_tag="AC1PIV_001477"
     CDS             6938..7723
                     /gene="proC"
                     /locus_tag="AC1PIV_001477"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HIP6612491.1"
                     /translation="MKIGFIGLGNMGAALAQAVSQQPDTQLLLSNHNPAKAQALQEKV
                     GGQLFSNGQIAEQAEIIFLGVKPHLIQTVLSGLQDQISQNPSAIWISMAAGVPLDSLA
                     AFVSADKVIRIMPNTPVAIGQGMTTYSLVNQNLAPLLEQILEKSGKVQQVPESLIDAA
                     TAIAGCGPAFVYQMIEALTDAGVQNGLTAQDAKVLAAQTLAGTAQMVLTSDKHPAQLR
                     QEVTSPGGSTIAGVVALEKEGFRYAIIKAVAAALKKTRKLGKK"
     gene            complement(7746..8150)
                     /locus_tag="AC1PIV_001478"
     CDS             complement(7746..8150)
                     /locus_tag="AC1PIV_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HIP6612492.1"
                     /translation="MAGRKISPQSLKNLYQSNKEANQLTKESIETALLFLLEKKELKQ
                     ISVSELVRKAGVSRNAFYRNYKSKEEILEDYYERTSSNLKKKWHDLQDKVQKDGVKQS
                     FADFVQEQKRKAEQSKALSNVSQWIKEKTKRD"
     gene            8277..9128
                     /locus_tag="AC1PIV_001479"
     CDS             8277..9128
                     /locus_tag="AC1PIV_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008289 - lipid binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HIP6612493.1"
                     /translation="MTKWKIVADSGCDYRQLANLAPDTEFISVPLTIQVGEQAFVDDA
                     SLDIDHMMEVMEASKSAAGSACPSPQAYQAAFEGAENIIVVTITGGLSGSFNAARVAR
                     DMYIEEHPNVNIHLIDSLSASGEMDLLVDEINRLISAGLDFPQVVEAITHYREHSKLL
                     FVLAKVDNLVKNGRLSKLVGTVVGLLNIRMVGEASAEGKLELLQKARGHKKSVTAAFE
                     EMKKAGYDGGRIVMAHRNNAKFFQQFSELVKASFPTAVIDEVATSGLCSFYAEEGGLL
                     MGYEVKA"
     gene            complement(9227..10486)
                     /locus_tag="AC1PIV_001480"
     CDS             complement(9227..10486)
                     /locus_tag="AC1PIV_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HIP6612494.1"
                     /translation="MKKYQVIIQDILTGIEEHRFKRGEKLPSIRQLREQYHCSKDTVQ
                     KAMLELKYQNKIYAVEKSGYYILEDRDFQDHTVELNPTDFQELPYEDFRICLKESLIG
                     RENYLFNYYHQQEGLAELISSVQSLLMDYHVYTKKDQLVITAGSQQALYILTQMETLA
                     GKTEILIENPTYSRMIELIRHQGIPYQTIERNLDGIDLEELESIFQTGKIKFFYTIPR
                     LHNPLGSTYDIATKTAIVKLAKQYDVYIIEDDYLADFDSSHSLPLHYLDTDNRVIYIK
                     SFTPTLFPALRIGAISLPNQLRDIFIKHKSLIDYDTNLIMQKALSLYIDNGMFARNTQ
                     HLHHIYHAQWNKIKDCLEKYALNIPYRISKGSVTFQLSKGILSPSIQHMFGKCYYFSG
                     QKADFLQIFFEQDFADKLEQFVRYLNE"
BASE COUNT         3014 a         2096 c         2455 g         2968 t
ORIGIN      
        1 cataagcatt tcttccaata ggaattcccg tgtcgaatct tggtacttcg tttttcccac
       61 tccctaggat tttttattat atgactttta gtccatcaca atccgtaaag tatgtgacaa
      121 atgaaccgag gatgggcaaa aaatggtcct ataatttctg tagcgggtaa aaccactatg
      181 gagcctttta aatgtaaaag tcatatgacc tataatgaaa agcgaaaaaa cttacattag
      241 aaagaggtca tatggaataa atcaagagtt aggggagtga ctcttgattc ctgagcctag
      301 aaatagaaaa gcgaagatct tatcacaaat tttcttggaa tagaagacaa aaatatcgct
      361 atcatgactg aatatgatgt ggaaactcac ttagattgtg tgtctccaaa atgtcttgcc
      421 tgaaagggac aaatagtgaa atacaacttc caaagagcat ctaaaatcct ttgcttagaa
      481 gcagctgata atcctctctc cttatccatc ttagaaagcg tcggttcaag tgtaaaggat
      541 gcgggaaaat ggttgtcgct gaaattcact tattaaaaaa acgaccaaat ctctgttgct
      601 attaaccaga aaacccccca attactactc gttgagaatc aagcaatgag taagcaatgt
      661 tcacctgata ctattgtcat caaggatagc ttttctatcc tattcggaac tataaagtaa
      721 gagtttttga agggggtaga tattggttgc atgtattgaa aaacttgtgg ttccatggtt
      781 tttaaagtta ctctatctgg ctatattttg aactatgtta ttacaccagt ttctgattat
      841 gtagtgaatt gcttgttgga aggctatcag taatctgtga ttttagcaga tttagtcagg
      901 agtttaaaga caacttggaa cagaaggata gaacatggaa ggagttaatt agtataacaa
      961 atggagatta ttagccatga ggcgaaccat tgaaactcgt tttctgaatc atacgctttg
     1021 tttgatatag aacaaacctt tgccagagga ctgctcggat tacagctacg gattgaacaa
     1081 atcctactta tctacaatct aagctatttt gactttaact agtagcacgg gtaaaaaaac
     1141 tgcctagttc aatcagaact gggcagtact tattttacat tctaaaaaat ggattgaaat
     1201 ttttctcatg tccaacgctg gtattttgac catgacctgg atggacagta tagtgatttg
     1261 gcagggtaaa gatatgttct ctgatgccag taatcaggtc atcaaagttg ctggttggca
     1321 ggtctgtgcg tcccacagtt tcacggaaaa gtgcgtctcc agtgatgaca cattcatcct
     1381 ctgggaagat aaaggaaaca ccaccaatag agtgaccagg tgttggaact accttgaaat
     1441 gaaaaccgtc aaactggtag tcttcttggt attggaagat tttttcagca ggtcggcaga
     1501 ctacattttc catatcatca tgacgaggta gacctgatag attcatctct ggtgtgtaga
     1561 gccagctggc ttcattttca gccacataga caggcgggaa attgtaggtc tcacgcagga
     1621 tgtccaaact cataatatgg tcatagtgag tgtgagtcag gagaatagcc gaaattggtt
     1681 ttccgatttt ttcgatagtt acttgaattt ttgtccagtc actcccaggg tcaatgataa
     1741 tcagatgggt atcattttca aggtagtagg tattttgaaa agcgacagga ttgacagatt
     1801 tgtgaataat cattcttttt ccttcttcta acagttactg atgttactag tctaacaaaa
     1861 aaacacgcct tcttcatgga atttgtttgg agctttttcc atgagaggga atatgctata
     1921 atgaacagta tgaaagacac aagaacaagc aatcggtatg ccgttgtaga tttggaagca
     1981 actggtacag gtaccgatgc aaaaatcatt caaatcggga ttgttctcgt tgaaaatgga
     2041 gaaatcattg acagttatgc aacggatatc aatccctatg agctactgga tgaccatatc
     2101 aagaatctga caggtatcac agaccaacag ctaagtcagg ctccagattt tggtcaggta
     2161 gcaagtacca tttacgacat gattggagat gctatttttg tagcccataa tgtcaaattt
     2221 gatgctaatc tcttggcaga agcactcttt tttgaaggtt atgaactgtt gacaccgcgt
     2281 gtagatacgg tagaattatc acagctattt ttcccgactt ttgaaaaata tagcttggga
     2341 aaccttgcag agcatttgga acttggtttg gaccaggcac acacggccat atcagatgcc
     2401 atggctacgg cgcgcttgct catcaaaatt caagagaaaa taaagagctt acccaggtct
     2461 attgttgaaa agattcttga tttggcggac aatctgctct ttgaatcccg tttggtcatt
     2521 gatgagatgg tgcctgttct gtcagaaaat ctatcatacg atttagaatc tattcatgac
     2581 ttggtcttga aaaagccaga agaaatcaag tcagcctacc gattatctga agatttttcg
     2641 accaatattg cccttctcgg cttgcatgaa cgaaaaaaac aaactgcttt tgctcaagta
     2701 gtagaaaaac gcttggttga cgaagaaaaa gtgcatttta ttcaagcgca ggcaggtttg
     2761 gggaagactt acggttatct cttgccttta cttgctaagt cagaccagcc tttattggtc
     2821 accgtaccga ccaagctcct tcaagagcag attatggaaa aggaagggag caagcttaaa
     2881 gagatatttc gtattcccat agtctctcta aaatcaccca agcattttat caagttagac
     2941 aactactgga aaaccctgca gaggcaggat gataatcgcc tggtcaatca attcaaaatg
     3001 caggtgcttg tctggttatg cgaaaccacg acaggtgatt tggatgagct taagcaaaaa
     3061 caacgctatc aagcttactt tgatgagatt gcccacgatg ggaaattgga gcctgaaagt
     3121 cttttttggg gcttggattt ttggcaacga ttgaaccaac aagctctctc tagtagactg
     3181 ctcattacca accacgctta ttttctcagc catcttaagg accaagatcc tcacatggat
     3241 aagcgtatgg tggtgattga tgaagcacaa aagtttctct tggctgctga aaatctagcg
     3301 acggcttcgc aagatttgac aagtatgtta caagtattgc aaagtaaaaa ggatagagcg
     3361 acggctattt tggaccaacg tttgtatgag tcttgccagt ttgaactcaa ccactttttg
     3421 agtcgttttc gtcagcatgg tcaacgagag gttcaaaagg ctgaacttca ccaacttggt
     3481 cagaacctgg aggagcttgg agatgttgat ttgaacgact tgcatcagct catagactat
     3541 tacgatacct tttggttgga ggagaaaaat ttagaagaaa agcggcttgc ctatttgcgg
     3601 agctccaagg atagcctcct aaatgcgacc aactatctgc cagatactaa gattttctgc
     3661 atcagcgcca ccttgaccat cagcaaaaag gtcagtctgg cggatctgct gggctttgag
     3721 caggtcacct tggatttgat accgactcaa actgtgacca accagcggct actttttccg
     3781 acccatctcc ccgacatcct cgcttggacc aaggaggagc atgcagcata tttggctact
     3841 actttaggag agatagcaga gctgggacga ccgattttgg tcttgtttac atcgatttct
     3901 atgctcttgc aggtgtcgga tttgttagaa gacaataaca ttccccacct agcccagcac
     3961 aagcatggac aggaaatgac tctcaaacgc aaatttgaac gaggggaatg ccaaatttta
     4021 ctcggcacag gtgtattctg ggagggcgtt gactttgcca gtcagaatca attgattcag
     4081 gttattacaa ggctcccatt tgacaatcca aaggaccggt ttgtacaaaa aatcaatcac
     4141 catctgcgtg aagaagggaa aaatccattt tatgattaca gcctgcctat gatgatgatt
     4201 aagctcaaac aagccatcgg tcgtaccaat cgccatgaca aacaagattc actagtcttg
     4261 gttttggacc cgcgtgttca caccaaacgc tatggacagc aaattctgtc cttctttgag
     4321 aaagattatt taatgttaag tgtggatgcg aaagaaatag aaggagctat tcaagatttt
     4381 tttgaataag ttgaaaggga gccacaaggc ttccttttgt ttccagcgtt ttttaatgca
     4441 ctcatgatta ggaatctatt ccctctctcc ttgccgaata acagtgattt tctttatgat
     4501 taaaatatgg tataattttc caaatattag tttttgtgag aagagattat gacagaaaaa
     4561 acaattgtat ttaaggtcgg gacaagttct ctgacgcaag aaaatggcag tctggaccgt
     4621 atcaagatcg ctcggattac caatcagctg gctcagttgc accagaaagg ttaccagatt
     4681 gtgctggtga cgtcgggctc gattgctgct ggttttcgga gattgggatt tgacaagcga
     4741 ccgaccaaga ttgcggagaa gcaggcttct gcggccgttg gacaaggttt gctgattgag
     4801 gaatatacgc aaaatctaat gaaggacggc atcgtatcgg ctcagatttt actgacccag
     4861 gatgattttg cggatgccag acgttatcag aatgcctctc aagccttgca ggtcttgctc
     4921 aagcaacggg ctattcctat tataaatgaa aatgatacca ttgccattga ggagattaag
     4981 gtgggggata acgatacttt atctgctcag gtggcttctc tcttgaaagc agacctattg
     5041 gtgctcttga cggatgtgga tggactttac actgccaatc ctaacagcga tccgactgcc
     5101 cagcacttgc ctcaaattaa ggagattacg gaagatttat ttgccatggc agcaggagca
     5161 ggctcgtcca atggaacagg tggcatgacc accaaattgc aggcggccca gattgcgacc
     5221 aagtcaggcg tgcccgtctt tatctgctct tcaaaagagg ataccgccct cttgcaggcg
     5281 gtcacccaag ccaatcgtgg aacgctcttt ttagcagatg accatgccat gaaccaacgc
     5341 aagcagtgga tggccttcta tgctcggaca gacgcggcgg ttgaagtgga tgcaggagcg
     5401 gttgatgcta tgttgcacca gggccgcagt ttgttagcta ctggtgtcaa agccctcgaa
     5461 ggagactttg aagtgggcca ggtcgtagaa gtttacagcc aagcagacca tcgtttgatt
     5521 ggtaaaggtc gggtcaaact gtcctccaag gacttgcagg accagttggc aaatggcaga
     5581 gcagagggcg tgttgattca ccgcaacgat tgggtgagct tatagttgtt cagtttgtct
     5641 cgattatgtt gacgaacgag taaactgaaa gactaaatag gagaaattta tgacaacaac
     5701 acaagtatta ttagatagtt tattggccaa caaggcttct atcaacctag cgacaacaga
     5761 acagaaaaac caggctctat cagcaatggc agaccagttg gttgctcaga ctgaggcaat
     5821 tttagcaggc aatgccatcg acatggaaca tgcccaaggc aagattagcc aggtgatgca
     5881 ggaccgtttg ctgctgacag aggaacggat tgaagctatg gcagatggca ttcgtgcctt
     5941 gattggcttg ccagatcctg tcggattagt cttggaagaa tccactcggg cagacggctt
     6001 gaacatttgc aagaaatcca ttccctttgg tttggtggga atgatttacg aaagccgacc
     6061 aaacgtgact tcagatgccg ctgccttggc catcaagagt ggtaatgcgg tcatcttgcg
     6121 tggtggcaag gaagcttttc attcggccaa agcgattgtc acagcactca agagtggctt
     6181 ggaagaagct ggtgtctcac caaaggtcat cgagttagtc caagatacca gccgggtctc
     6241 tgcgacggag ttgatgaccg caaaaggcaa gattgattta ttggtgccac gtggtggagc
     6301 aggactcatt caagccgtag tagaaaatgc gactgtgcca gttattgaaa caggaacagg
     6361 tatctgccat gtctatgtgg acaaggatgc ggacttggac aaggccttgc ggattgtggt
     6421 caatgccaaa accagtcgtc cctcagtctg caatgcggcg gaagtcttgt tggtccatga
     6481 agaaattgcc agccaattcc tacctcgctt ggaagaagct ctttctggtc aggtggaatt
     6541 acgtgccgac agtcaggccc aggctctcct caaccaagcc agaccagcag gcgaccaaga
     6601 ttttgacaca gaatttttgg actatatcat ggcggtcaag gtcgtttcaa gtgtagaaga
     6661 ggctatcagc catatcgccc aacattcgac tggacatagc gaggcgattg tgacggaaaa
     6721 cagccagaca gcagagcatt ttacactcca tgtggactcg gcagcagtct atgtcaatgc
     6781 ctcgacccgc tttacagacg gtggagagtt cggtctgggc tgtgagctgg gtatttccac
     6841 ccagaagatg cacgcccgtg gtccaatggg actgcgtgaa atgaccactt acaagtacat
     6901 catcacaggc gacggccaca ttcgttagga ggacaagatg aagattggat ttattggact
     6961 gggcaatatg ggagcggccc tagcccaagc ggtcagccag cagccagata cccagctcct
     7021 cctcagcaac cataacccag caaaagccca ggctcttcaa gagaaggtag gcggtcagct
     7081 tttttctaat ggacaaatag cagagcaggc cgagattatt ttccttgggg tcaagcctca
     7141 cctgattcag acagtcttgt caggcttgca ggaccagatt agccagaatc cgtcagctat
     7201 ctggatttcc atggcagcag gagtgcccct tgacagcctg gcagcatttg tatcggcaga
     7261 taaagttatc cgtatcatgc ccaatacacc agtcgctatc ggccaaggca tgacaaccta
     7321 tagcctggtc aatcaaaatc tcgctccgct attggaacaa atcctagaaa aatcaggcaa
     7381 ggtccagcaa gtgccagaga gcctaatcga cgcagcaacg gctatcgcag gctgcggacc
     7441 agcctttgtc tatcagatga ttgaggctct gacagatgca ggggtgcaaa acgggctgac
     7501 ggcccaggat gccaaggtat tggcggctca gaccctggca ggaactgctc agatggtctt
     7561 aaccagcgat aaacacccag cccagctgag acaggaagtg acctcgccag gcggctcgac
     7621 tatcgcaggt gtggtagctc ttgaaaaaga aggcttccgt tacgccatta tcaaggcagt
     7681 cgccgccgcc ctcaaaaaga ctagaaaatt aggcaaaaaa tagaagacag caaaaaacgg
     7741 gacttttaat cccgttttgt tttttccttg atccattgac tgacgttgga cagggccttg
     7801 ctttgctctg ccttgcgttt ttgttcctgg acaaaatctg caaagctttg cttgacgccg
     7861 tccttttgaa ccttgtcctg caaatcatgc catttctttt taaggttgct ggaagtccgt
     7921 tcgtagtagt cttcaaggat ttcttccttg gacttgtaat tgcggtagaa ggcattgcgt
     7981 gacacaccag cttttcggac caattcagat accgaaattt gcttgagctc ctttttctct
     8041 aggagaaata gcagagcagt ttctattgat tccttagtca gttgattcgc ttctttattt
     8101 gattgataga ggtttttcaa agattggggt gaaattttac gacctgccat agttttcctt
     8161 ttccgagtgt cacatctgaa agaaaatgct ttcagatggg gtagtttaat gatataattg
     8221 taagtaaata gagatttatt gtcaaataaa aaaataaaat tggaaatgag aatattatga
     8281 caaaatggaa aatcgttgca gattcgggct gcgactatcg tcaattagct aatctagctc
     8341 cggacactga atttattagt gtgccactta ccatccaagt tggagaacaa gcatttgttg
     8401 atgatgcaag cttggatatt gatcacatga tggaggtgat ggaagcatct aagtctgcag
     8461 cggggtcggc gtgcccaagt ccgcaggctt atcaggcagc ttttgaggga gctgagaaca
     8521 ttatcgttgt gacgattaca ggtgggctat cgggtagttt taatgcggca cgtgtagcta
     8581 gggatatgta tatcgaagag catccgaatg tcaatatcca tttgatagat agtttgtcag
     8641 ccagtgggga aatggattta cttgtagacg aaatcaatcg cttaattagt gcaggattag
     8701 attttccaca agtagtagaa gcgataactc actatcggga acacagtaag ctcctctttg
     8761 ttttagcgaa agttgataat cttgttaaga atggaagact gagcaaattg gtaggcactg
     8821 tcgttggtct tctcaatatc cgtatggttg gtgaggcaag tgctgaagga aaattagagt
     8881 tgcttcaaaa ggcgcgtggt cataagaaat ctgtgacagc agcctttgaa gaaatgaaaa
     8941 aagcaggcta tgatggtggt cgaattgtta tggcccaccg caacaatgct aagttcttcc
     9001 aacaattctc agagttggta aaagcaagtt ttccaacggc tgttattgac gaagttgcaa
     9061 catcaggtct atgcagtttt tatgctgaag aaggtggact tttgatgggc tacgaagtga
     9121 aagcgtgatt cacagagtaa taattttggg ctgtaatttc cgctatagaa taatccccct
     9181 cgtcttctaa gttcgagggg gattgtttgt atgagactat tggatttcat tcattcaaat
     9241 atcttacgaa ttgctccagt ttatctgcaa aatcttgttc aaagaagatc tgtaagaaat
     9301 cagctttctg tccgctgaaa taataacatt ttccaaacat gtgttggatg ctaggagaaa
     9361 gaatcccctt gcttagctga aaggtcacgc tccctttgga aattcgatac gggatgttta
     9421 aagcgtattt ctctagacag tcttttattt tattccattg agcgtgataa atgtgatgaa
     9481 gatgctgtgt gttccgcgca aacataccgt tatcaatgta gagcgagaga gctttttgca
     9541 tgataagatt ggtatcgtag tcgattagac tcttatgttt gatgaagata tcacgtagct
     9601 gattaggaag gctgattgca ccgattcgga gggcaggaaa gagtgtcggt gtaaaagatt
     9661 ttatatagat gacgcgatta tctgtatcaa gatagtgtaa aggtaggcta tgactagagt
     9721 cgaaatctgc taaatagtca tcctcaatga tgtagacatc gtattgcttt gctaatttta
     9781 cgatggctgt ttttgttgct atatcatagg ttgaaccgag agggttgtgc aagcgaggaa
     9841 ttgtgtagaa aaacttaatt tttccagttt ggaagatact ttccaattct tctaggtcaa
     9901 ttccatctaa attccgttca attgtttgat aggggattcc ttgatgtcga atgagctcta
     9961 tcattcgtga ataggtaggg ttctctatca agatttccgt ttttccagcc aaggtttcca
    10021 tttgtgtgag aatatataga gcttgttgac taccagctgt gataaccagc tggtcttttt
    10081 ttgtatagac atgatagtcc attaacagac tttgaacgga ggaaatcaat tctgccaatc
    10141 cctcttgctg gtgatagtag ttgaataggt aattttcccg cccaataaga ctttctttta
    10201 gacaaatccg aaaatcttca tagggtaatt cttgaaagtc tgtaggattg agctctacag
    10261 tatggtcttg gaaatctcta tcctctaaga tataataacc gcttttttcg acagcgtaga
    10321 tcttattttg gtattttaat tccaacatag ccttttggac agtgtctttg ctacaatgat
    10381 attgctcgcg gagttgacgg atagaaggta atttctctcc acgtttgaat cgatgttcct
    10441 ctattccagt caaaatatct tggatgataa cttgatattt tttcatctag gtcccctttt
    10501 ttatagacta tgttactagc tagtatatag aaa
//
LOCUS       DBNFCO010000061        10361 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.061, whole genome shotgun sequence.
ACCESSION   DBNFCO010000061 DBNFCO010000000
VERSION     DBNFCO010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10361
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.061"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            289..840
                     /locus_tag="AC1PIV_001481"
     CDS             289..840
                     /locus_tag="AC1PIV_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HIP6612495.1"
                     /translation="MIVFLVICVFLVRIYFLKISIKNEKRILKNGGSEFGVQNTKLLT
                     IVHILFYLSCLVEAVVRHTKFDTLSSLGLIFLLFSMGMLFWVTRLLGDIWTVKLMLVK
                     DHRFVDHWLFRVVKHPNYFLNIIPELIGLALLCHATYSFLILFPVYMVILYRRIHEEN
                     NLLKTVIIPNGTVQSAAEITGNN"
     gene            complement(1049..1957)
                     /gene="ypfJ"
                     /locus_tag="AC1PIV_001482"
     CDS             complement(1049..1957)
                     /gene="ypfJ"
                     /locus_tag="AC1PIV_001482"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014917295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KPN_02809 family neutral zinc metallopeptidase"
                     /protein_id="HIP6612496.1"
                     /translation="MKIDDLRKSSNIEDRRGQSSSNSSFSSGSSGGNVLLGLIFSRLG
                     WKGKLLVLVLLVAFGGMSNLGGLLSPSTGTNPYQSSQVTTTGTDVSDADAEFMSKVLG
                     STEDFWVQEFKANGLTYNAPTMVFYTNQTQTGCGVGSAQAGPFYCSADRKIYIDTSFY
                     QELSSKYKAAGDFAMAYVIAHEVGHHVQNELEVLGAYHQKRAQLSDKEGNALNVRLEL
                     QADYYAGAWAKYVDGQGILDAGDIDEAMNAAHAVGDDTLQQEAYGRTVPDSFTHGTSE
                     QRKKWFNLGYTYGDLAHANTFSVEKP"
     gene            2125..3468
                     /gene="xseA"
                     /locus_tag="AC1PIV_001483"
     CDS             2125..3468
                     /gene="xseA"
                     /locus_tag="AC1PIV_001483"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HIP6612497.1"
                     /translation="MVEYLSVSHLTKYLKLKFDRDPYLEKVYLTGQVSNFRKRPSHQY
                     FSLKDDKAVIQVTMWAGVYKNLGFELEEGMKINVIGRIQLYEPNGSYSIVIEKAEPDG
                     IGALAIKFEQLKQALTQEGLFKEEFKQALPRFTKKIGVITSPSGAVIQDIITTVSRRF
                     PGVEIVLYPTKVQGDGAAQEVVTNIQRANERDDLDVLIVGRGGGSIEDLWAFNEEIVV
                     RAIFESRIPIISSVGHETDTTLADFVADKRAATPTAAAELATPVTKADLLGYLNQQEN
                     RAYQAMTNRLRFLRGQLEKISQSVMFRQPERLYDGYLQKLDRLTNQLQTRMKELYSQQ
                     KQACLLLQQRLQGVHPGRKVESFQERIIQQERLLKSNMANIYDNKMAKADKLIEALTM
                     LDTSRIVARGYAMIRQDGRVIDSVENVQMGENLTIQMKDGQLDVEVKHVQTDENI"
     gene            3443..3658
                     /locus_tag="AC1PIV_001484"
     CDS             3443..3658
                     /locus_tag="AC1PIV_001484"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009910558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HIP6612498.1"
                     /translation="MSKQTKTFEENLAELEGIVTKLERGDVALEEALAEFQKGMVLSK
                     DLQKTLAEAEKTLVKVMQADGSEAEMD"
     gene            3658..4527
                     /locus_tag="AC1PIV_001485"
     CDS             3658..4527
                     /locus_tag="AC1PIV_001485"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HIP6612499.1"
                     /translation="MVTSKLQRLEEAMADFYQPQVAERLNQSVLYSLQAGGKRIRPLL
                     LLTILESFGMELKQAHYQVAACVELIHTGSLIHDDLPAMDNDDYRRGRLTNHKVYDEA
                     TAILAGDSLFLDPFGFLAQVDLPAETILALVRELSQASGTFGMVAGQVLDMAGEGQNL
                     TLEQLQAIHANKTGKLLTFPFVAAGLIAGQSDVVINHLRQAGQLIGLAFQVRDDILDV
                     TATFEEIGKTPQKDVLAEKSTYPALMGLEASKVFLEDSLNQAINELDQVAKQVPFSTE
                     KIKEIIESLRING"
     gene            4520..5341
                     /locus_tag="AC1PIV_001486"
     CDS             4520..5341
                     /locus_tag="AC1PIV_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family rRNA
                     (cytidine-2'-O)-methyltransferase"
                     /protein_id="HIP6612500.1"
                     /translation="MAKERVDVLAFKQGLFETREQAKRGVMAGLVISVINGERYDKPG
                     EKIDEGIELKLKGEKLKYVSRGGLKLEKALQVFHLSVEGQTTIDIGASTGGFTDVMLQ
                     AGAKQVYAVDVGTNQLAWKLRQDERVISMEQYNFRYAELGDFELGQPSFASIDVSFIS
                     LSLILPALHRILAEGGQVVALVKPQFEAGREQIGKNGIVKDKSVHLKVLEEVTKMAVE
                     TGFSVKALSFSPVQGGHGNIEFLAHLEKSTQPNQIDKEVITTTVYQAHEEFKKDE"
     gene            5334..5759
                     /locus_tag="AC1PIV_001487"
     CDS             5334..5759
                     /locus_tag="AC1PIV_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HIP6612501.1"
                     /translation="MNKRERLEVIKDLVVRFPIDTQEEIVERLEAMGVNATQATVSRD
                     IKELGIIKVPSADKGYIYGLPKAGLVKVKSQNVFEVSVMDKMINLRLVPGSSAVVKRQ
                     ILEQFQEHVFSVIADDDSILLIVTNEGIISQIEQTVRGW"
     gene            5762..7423
                     /gene="recN"
                     /locus_tag="AC1PIV_001488"
     CDS             5762..7423
                     /gene="recN"
                     /locus_tag="AC1PIV_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HIP6612502.1"
                     /translation="MLLEVSIKNFAIIEQVSLNFENGMTILSGETGAGKSIIIDAMNL
                     MLGARATTDVIRHGAAKAEIEGLFSFENSRALEQILLEQGIEVADELIIRREILQNGR
                     SVSRVNGQMVNLSVLKQIGQYLVDIHGQHDQEELMKSQHHIRLLDSFGEDEFWSLKDR
                     YQTTFDAYRSLRKRVLEKQKNEQEHKARIEMLEYQIAEIEAADLKSGEDIQLNQERDK
                     LLNHKQIADTLTNAYALLDNEDFSSLNNLRSAMSDLQSLEEFDPDYKQLSSSLTEAYY
                     VVEDITKRLSDVVDNLDFDGNRLMQLESRLDLLNTITKKYGGTVDDVLDYFSKISEEY
                     NLLTGNDLSGDDLEVQLKNLEKELVERAGQLSQSRHELAVVLEDIIRQELQDLYMEKA
                     RFQVRFTKGKFNREGNETVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFARKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIYKIGQYGQVLAISHLPQVIAIADYQFFIEKIS
                     DEHSTVSRVRLLTKEERIEEIAKMLAGDKITDAARNQAKELVEKG"
     gene            7517..8350
                     /locus_tag="AC1PIV_001489"
     CDS             7517..8350
                     /locus_tag="AC1PIV_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HIP6612503.1"
                     /translation="MSKIKIVTDSSTTIEPSLVEELNITVVPLSVMVDGVVYSDNDLK
                     EGEFLELMRGSKNLPKTSQPPVGLFAETFAELAKDGSQIIAILLSHALSGTVEAARQG
                     ATLSGADVTILDSSFTDQAEKFQVVEAARMAQAGASKEEILAAIETVKEKTELYIGVS
                     TLENLVKGGRIGRVQGMLSSLLNIRVIMEMKDHQLTPIVKGRGNKTFKKWLEEFTATL
                     ADKKVAEIGISYSGTADFANEMKSQLQEYVSKEISVLETGSIIQTHTGEDAWAILLRY
                     E"
     gene            8343..9176
                     /locus_tag="AC1PIV_001490"
     CDS             8343..9176
                     /locus_tag="AC1PIV_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014917294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HIP6612504.1"
                     /translation="MNNRKLIQGFVFFFLTILGSIFLFHQLIPVASSRISRQELTVSE
                     KISFRYVALGDSLTEGVGDTTGQGGFVPLLAQSLTNDYGYEVDYKNFGVSGNTSNQIL
                     KRMKEDGELISYLKTADLLTLTVGGNDLRKAIIKNIANLKVSTFDKPAKDYGKQLDTI
                     IKTARKNNPNLPIYVVGIYNPLYLNFPELTEMQTIVDNWNTMTEQITEKYQHVYFVPI
                     NDLLYKGLEGEAGISQNGSQVTNNLLYEEDSFHPNNTGYEIMKKAILERMNETTESWE
                     P"
     gene            9148..9744
                     /locus_tag="AC1PIV_001491"
     CDS             9148..9744
                     /locus_tag="AC1PIV_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HIP6612505.1"
                     /translation="MRPRKAGNLNIWKWLFLAQLSLLIGCGIVLYTRIQTDREDLTKL
                     VQTSTEDTKVGTFSTNREQLNQTLTNYLKEYQTEEFSYQLFVTSQQVVFEGSYQIFGV
                     TIPLYIYFQPSKMEDGSILLRITEISVGSLSLPKAEVLAYLQKNYKLPAFVKIDSEQA
                     QVQVQLTELKNKFGLYGKANTIDLYNDQFIVDIYRKRQ"
     gene            9834..10109
                     /locus_tag="AC1PIV_001492"
     CDS             9834..10109
                     /locus_tag="AC1PIV_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030527 - structural constituent of
                     chromatin [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HIP6612506.1"
                     /translation="MANKQDLIAKVAEATSLTKKDSAAAVDAVFGAVADYLAAGEKVQ
                     LIGFGNFEVRERSARTGRNPQTGAEIKIAASKVPAFKAGKALKDAVK"
BASE COUNT         3248 a         1903 c         2317 g         2893 t
ORIGIN      
        1 gaactcgctt tgctgtactc tgcaggggtg acttgctccg caagtgctat ctccaacctt
       61 gcacagtcac tcgactgtac aagctgtctg cagctcgttg actggtacta aaagtaaact
      121 aaaagactat aaaagagaca tgatttcatc catttttgaa aacaggtctc ttttattgta
      181 gtctcaaatg gaaaatagaa aaaaaacagg agaggaatag aatggcgaca gtctaacttt
      241 gtataatgga tgtgtttgat aaaatctgtt aaaatacagg agggatttat gattgttttt
      301 ttggttattt gtgttttttt ggtgagaatc tattttttga agatttcaat taaaaacgaa
      361 aaacggattt tgaaaaacgg cggttcagaa tttggtgttc aaaatactaa attattaaca
      421 attgtacata ttctatttta tttatcatgt ttggttgaag cagtagtgcg acacaccaag
      481 tttgatacgc ttagtagctt aggtttgata ttcttgctgt tttcaatggg aatgttattt
      541 tgggtaacac gattgttagg tgatatttgg acagttaagc tcatgttggt aaaagatcat
      601 cgttttgttg atcattggtt gtttcgtgtt gtaaagcatc ctaactattt cctaaatatt
      661 ataccagaat taatcggttt agctttattg tgtcatgcaa catatagttt tctcatctta
      721 ttcccagtct acatggttat cttatacaga cgtattcacg aggaaaataa tttgttgaaa
      781 acagtgatta ttccaaacgg aactgtgcag tctgcagcag agataactgg aaataattaa
      841 agtttgctaa ataataattg tgatattgtt tgaaactagg ataccgctct aattagagtt
      901 gatgagtaag tttacatgat tcagttttca tatttaaaag tggtaccgta tgtgtaaatt
      961 ggcttttgtc agttgtatat tataaagaaa ctcttgcaaa agtgtatgtt gcaagagttt
     1021 ctttattgct acgagaggct atggatgttt acggtttctc tacggagaat gtattggcgt
     1081 gagcaaggtc accataggta taaccgagat taaaccattt tttcctttgc tcagaagtgc
     1141 cgtgggtaaa actgtctgga acagtacggc cgtaggcttc ctgttgaaga gtatcgtcac
     1201 caactgcatg ggcagcattc atggcttcgt caatatcacc agcatccaag atgccttgtc
     1261 catcaacata tttggcccag gctcctgcat aatagtcagc ttgcaattct aaacgaacat
     1321 ttagcgcatt gccttcctta tcggatagtt gagcccgttt ttgatggtag gccccaagaa
     1381 cttctaattc attctgaaca tggtgaccaa cttcatgagc gatgacatag gccatggcaa
     1441 agtcaccagc agccttatac ttgctagata attcttgata gaaagaagta tcaatataaa
     1501 tcttgcggtc agcagagcaa tagaatggac cggcttgggc ggaaccaact ccacatccgg
     1561 tttgggtctg gttagtatag aaaaccatag tcggtgcatt gtaggttaaa ccattggctt
     1621 taaattcttg gacccaaaaa tcttctgtcg atcctaaaac cttactcatg aattcagcat
     1681 ctgcatcaga cacatctgta ccagtcgttg tgacttgact cgattggtaa ggattagtcc
     1741 ctgttgatgg ggaaagcaac ccaccaaggt ttgacatgcc tccgaaggct actaaaagga
     1801 caagaacaag tagttttcct ttccaaccaa gtcgtgaaaa gattagtccc aatagaacat
     1861 ttccgccaga tgaaccagac gagaaagatg agttagaact ggattgtccc ctgcggtcct
     1921 caatgttaga actttttcgc aaatcatcaa ttttcatata aatctcctta gaacctgtca
     1981 acaagttctt attttctcac aaactattat atagcaaatt gttgaaaaaa aacataggaa
     2041 agctatcgga aataataggc ctagttctgt ataaaagtgc aaaatttggt ataatagtag
     2101 ggatacaata tagaaggagt ggacatggtt gaatatttat cggttagtca tctaactaag
     2161 tatttaaaat taaagtttga ccgcgatccg tatttggaga aggtgtattt gacaggtcaa
     2221 gtgtccaact tccgtaaacg ccctagccat caatattttt cgctcaagga tgacaaggca
     2281 gtcatccaag tgaccatgtg ggcaggcgtc tataagaatc tgggctttga gcttgaagag
     2341 ggaatgaaaa tcaatgtcat tgggcgcatt cagctctatg aaccaaatgg ttcttattct
     2401 attgtcattg aaaaagctga gccagatggt attggagcct tggcaatcaa gtttgaacag
     2461 ctcaaacaag ctctgacaca ggaaggctta tttaaagaag aattcaagca ggccttgcca
     2521 cggtttacca agaaaatcgg tgtcattacc agtccgagtg gagctgttat tcaggatatt
     2581 attacaaccg ttagccgacg ttttccaggc gtagagattg ttctctatcc gaccaaggtg
     2641 caaggagatg gtgctgctca ggaggttgtt actaatattc aaagagccaa tgaacgggat
     2701 gacttggatg ttctgattgt tggtcgtggc ggtggttcta tcgaagacct ttgggctttc
     2761 aatgaagaaa ttgtggttcg ggctattttt gaatcccgta ttccaatcat ttccagcgta
     2821 ggtcatgaaa cagatacgac cttggctgat tttgtagcag ataaacgagc tgctacccca
     2881 acagctgccg cagaattagc aacacctgtg accaaggcgg acttactggg ctacctcaat
     2941 cagcaggaaa atagagccta tcaggccatg accaatcgtt tgagattcct aagaggtcag
     3001 cttgagaaaa ttagccagtc agtcatgttc cgccagcctg aacgcttgta tgatggttat
     3061 ttgcaaaaat tagaccgctt gaccaatcaa ttgcagacac ggatgaaaga actctacagc
     3121 cagcagaaac aggcttgtct cctactacag caacgattac aaggtgtgca tccaggtcgt
     3181 aaagtagaaa gtttccaaga gagaattatc cagcaggaac gactcttgaa gagcaatatg
     3241 gctaatatct atgacaataa gatggccaag gcggacaagc tgattgaggc cctgactatg
     3301 ctggatacca gtcgcatcgt agcccgtggc tacgccatga ttcgtcaaga tggtcgggtg
     3361 atcgatagtg tagaaaatgt acaaatgggt gaaaacctaa ccatccagat gaaggatggt
     3421 caacttgatg tggaggtaaa acatgtccaa acagacgaaa acatttgaag aaaacttagc
     3481 tgaattagaa ggaatcgtaa ccaaattgga gcgaggcgat gtggctctgg aagaagcact
     3541 ggccgagttt caaaaaggaa tggttctatc gaaagaccta caaaagacac tagcagaagc
     3601 tgaaaagacc ttggtcaagg tcatgcaggc ggatggcagt gaagcggaga tggattaatg
     3661 gttaccagta aattgcagcg acttgaggaa gccatggcag acttttacca accccaggta
     3721 gctgaacgcc tcaaccaatc ggttctttat tcgctacagg ctggtggtaa acgaatccgc
     3781 cccttgcttt tattgaccat cttagagtcc tttgggatgg aattaaaaca agctcattac
     3841 caagtggcag catgtgtcga gttgatccat acgggaagtt tgattcacga tgacctgcct
     3901 gctatggata atgatgatta ccgtcgtggt cgcttgacca accacaaggt ttacgatgaa
     3961 gcaacggcta ttttagcagg ggacagtctc tttctagatc catttggttt cctagcccaa
     4021 gttgatttac cagctgagac catccttgct ctcgtgagag agctttccca ggcatctggg
     4081 acctttggaa tggttgctgg tcaagtcttg gatatggctg gtgaagggca gaatttgacc
     4141 ttagaacaat tacaagccat ccatgccaat aagactggaa aattattgac atttcccttt
     4201 gtagcagcag gtttgattgc aggacaatca gatgtggtaa tcaaccattt gcgacaagcg
     4261 ggtcaattaa ttggtctagc ctttcaagtt cgggatgata ttttggatgt gacagccact
     4321 tttgaggaaa tcggaaaaac tccccaaaaa gatgtattgg ctgagaagtc tacctaccct
     4381 gccctaatgg gactggaagc ctcaaaagtc tttctagaag atagcttgaa tcaagcaatc
     4441 aacgagctag atcaagtggc taaacaagtc ccattttcaa cagaaaaaat caaagaaatc
     4501 atagaaagtt tacgaatcaa tggctaagga aagagtagat gtactagctt ttaaacaggg
     4561 gcttttcgag acgcgggagc aggccaaacg cggtgttatg gctggcttag ttatatccgt
     4621 cattaacggg gaacgctacg ataaaccagg tgagaagatt gacgagggaa ttgaactcaa
     4681 gctcaagggg gaaaaactca agtatgtcag ccgtggtggt ctcaaattgg agaaagcctt
     4741 gcaggttttc cacttatcag ttgagggtca aacaacgatt gatattgggg cttcaacagg
     4801 cggatttacg gatgttatgt tgcaggctgg tgccaagcag gtctatgctg tggatgtagg
     4861 gaccaaccaa ctcgcttgga aattacgtca ggacgaacgt gtaatcagca tggaacagta
     4921 caatttccgc tatgctgagt tgggagattt cgaacttggt caaccaagtt ttgcgtccat
     4981 tgacgtcagc tttatctcat tgagtctgat tttgccagca ctccatcgta ttttagcgga
     5041 gggtggccag gttgttgccc ttgtcaaacc ccaattcgag gctggacgtg aacagattgg
     5101 gaaaaatggc attgttaagg ataaatccgt tcacttgaaa gtcttggaag aagtgacaaa
     5161 aatggccgtg gaaacaggct tctcagtcaa agcccttagc ttttcccctg ttcaaggcgg
     5221 tcatggcaat atcgaatttt tagcgcactt agaaaaatca acacaaccaa accagattga
     5281 taaagaggtc ataacaacta cagtctatca agcacatgag gaatttaaaa aggatgaata
     5341 aacgagaacg attagaagtc attaaagatt tggtagtccg atttcctatt gatacacagg
     5401 aagaaattgt tgaacgtcta gaagcaatgg gtgtcaatgc gacacaagca acggtttcac
     5461 gtgatatcaa ggaacttggc attattaagg ttccatcagc agataaggga tatatttatg
     5521 gtttaccaaa ggcaggtctt gttaaggtaa aatcgcagaa tgtttttgaa gtctcagtga
     5581 tggataaaat gattaatctc cgtctggtac ctggaagctc tgctgtggtc aaacgccaga
     5641 ttttggaaca atttcaagaa catgtttttt cagtgattgc tgatgatgac agtattctgc
     5701 tcattgttac aaacgaaggt attatttcgc aaatcgaaca gacggttaga gggtggtagc
     5761 catgttacta gaagtgtcca ttaaaaactt cgccattatt gagcaggtat cactgaattt
     5821 tgaaaacggg atgaccatcc tatctggtga aacaggtgca ggtaaatcca ttatcattga
     5881 tgccatgaac ctgatgctag gggcgcgtgc gacgacagat gttatcagac atggggccgc
     5941 caaggctgag attgaagggc tcttttcctt tgaaaatagc agagctctcg agcaaatttt
     6001 gcttgaacag gggattgaag tagctgacga actcattatc cgccgtgaaa tcctgcaaaa
     6061 tggccgttcg gtcagccgtg tcaatggaca aatggtcaat ttatctgtct tgaaacagat
     6121 tgggcaatat ttagtagata ttcatggtca acatgaccag gaagaattga tgaaatccca
     6181 gcaccatatc cgtcttttgg acagtttcgg agaagatgaa ttttggagtc ttaaagaccg
     6241 ttatcagaca acctttgatg cctatcgtag tcttcgcaaa cgagttcttg aaaagcaaaa
     6301 aaatgagcaa gaacacaagg cgcggattga gatgctagaa taccaaattg ctgaaatcga
     6361 agcagcggat ttgaagtctg gggaagatat tcaactcaat caggaacgcg ataaactgct
     6421 caaccacaaa caaattgcag atacactgac caatgcctat gcactgttag acaatgaaga
     6481 tttttcaagc ttgaacaacc tacgctcagc tatgagtgac ttgcaaagtc tggaagaatt
     6541 tgatccagac tacaaacagc tctcttctag cctgacagaa gcttattatg tcgttgaaga
     6601 tataaccaag cgtctcagcg atgtggtcga taatctagat tttgacggca atcgtctcat
     6661 gcaattggaa agtcgtctgg atttgctcaa taccattacg aagaaatatg gtggaactgt
     6721 cgatgatgtt ttggactatt ttagtaaaat cagcgaagaa tacaatctat tgacaggcaa
     6781 tgatttatct ggagatgatt tggaagttca gcttaagaac ttagagaaag aattggttga
     6841 acgagcaggt cagctcagcc aatcacgcca tgaattggct gttgttttag aagatattat
     6901 ccgccaagaa ttgcaagact tgtatatgga gaaagctcgt ttccaagttc gatttactaa
     6961 aggaaaattt aatcgagaag gaaatgaaac agtagaattt tacatctcta ccaacccagg
     7021 tgaagacttc aagcctctgg ttaaggtggc ttctggagga gaattgtctc gcttgatgtt
     7081 ggccattaag tcagcctttg cccgtaaaga aggcaagact tccatcgtct ttgacgaggt
     7141 ggatacaggg gtgtctggac gtgtggccca ggccattgcc cagaaaattt ataaaatcgg
     7201 acaatatggg caagtattgg cgatttctca tctaccacaa gtcattgcta ttgcagatta
     7261 tcagttcttt attgagaaaa tatccgacga acattcgacc gtttctcgtg tccgtctctt
     7321 gaccaaagaa gagcgtattg aggaaattgc caagatgtta gccggtgaca aaatcacaga
     7381 tgcagcccgt aatcaagcaa aagaattagt agaaaaaggt taggcgacta gcctttttgc
     7441 ttatgtccaa agtttatttt ttagttaaaa tttgttataa tagatggcaa aattgaagag
     7501 aattgtagga tgaaatatgt caaagattaa gattgttacg gattcaagta cgactatcga
     7561 acccagtttg gtcgaagaat tgaatataac agttgttcca ttatctgtaa tggttgacgg
     7621 agtcgtatac tctgacaacg atttaaaaga aggagaattc ttagagctca tgcgtgggtc
     7681 gaaaaacttg ccaaaaacaa gccagccccc agtaggactc tttgcggaaa cttttgctga
     7741 attggctaaa gacggcagtc agattattgc cattctcttg tcgcatgcct tgtcagggac
     7801 agtagaagct gctagacaag gagcaaccct ttctggtgct gatgtgacaa tactcgattc
     7861 aagctttaca gatcaggctg aaaaattcca agttgtagaa gcagcacgca tggcacaagc
     7921 tggtgccagc aaagaagaaa tccttgcagc tattgaaaca gtcaaagaaa aaacggaatt
     7981 atacatcggt gtatcaaccc tagaaaatct agtcaagggt ggtcgtattg gacgtgttca
     8041 agggatgctg agtagcctac tcaatatccg tgtcatcatg gaaatgaaag accatcagct
     8101 gactccgatt gtcaagggac gaggcaataa gacctttaaa aaatggctgg aagagttcac
     8161 ggcaactcta gcagataaaa aagtagccga gattggtatt tcctattcag gaacggcaga
     8221 ttttgcaaat gaaatgaaga gtcaattaca agagtacgtc tcaaaagaaa tttctgtttt
     8281 agagacaggt tccatcattc aaactcatac tggtgaggat gcctgggcta ttttgcttcg
     8341 ttatgaataa taggaagttg attcaaggct ttgttttctt ttttctgaca attctagggt
     8401 cgatttttct atttcatcag ctcattcctg ttgcctcatc tcgcatctcc agacaagagc
     8461 ttaccgtatc agaaaaaatc agttttcgat atgtggcact tggtgattct ttgacagaag
     8521 gtgttggaga tacaactgga caggggggat ttgttccctt gttggctcaa tctctaacta
     8581 atgattatgg ttatgaagta gattataaaa atttcggagt ttctgggaat accagtaatc
     8641 agattcttaa acgaatgaag gaagatggag agctgataag ttacttaaaa acagcagatc
     8701 tgttaactct gacagttggt ggcaacgatt tgcgcaaggc tattattaaa aacattgcca
     8761 atctcaaagt ttcaactttt gataagcccg caaaagatta cggaaaacaa ttggatacaa
     8821 ttattaagac agcgcgtaag aataatccaa atcttcccat ctatgttgtc gggatttaca
     8881 atccactcta cctcaatttt cctgaattga cagaaatgca gacaattgtt gataattgga
     8941 atacgatgac agaacagata actgaaaaat atcagcatgt ctactttgtt ccgatcaatg
     9001 atttgcttta taaaggattg gaaggggagg ctggtattag tcaaaatggt agccaagtta
     9061 ccaataattt actgtatgag gaagacagtt tccatcccaa taatactgga tatgagatta
     9121 tgaaaaaagc gatattggag agaatgaatg agaccacgga aagctgggaa ccttaatatt
     9181 tggaaatggt tatttttagc ccagttgtct ttattgattg gttgcggaat agtcctctat
     9241 acacggattc aaacagatag agaggattta acaaagctcg ttcagactag tacagaagac
     9301 acaaaggttg ggaccttctc cactaatagg gaacagctca accaaaccct cactaactat
     9361 ctaaaagagt atcagacgga agagttttcc tatcaattat tcgtaacgag tcagcaagtt
     9421 gtttttgaag gcagctatca gatttttggt gtgactatcc cactctatat ttattttcaa
     9481 cctagcaaaa tggaagatgg cagtattttg ttacggataa cagaaatatc agttggaagt
     9541 ttatccttgc cgaaagcaga ggtattagct tatttacaaa aaaattataa actacctgcc
     9601 tttgtaaaaa tagactcaga acaagcgcaa gtacaggttc aactgacaga actgaagaac
     9661 aaatttggtc tgtatggaaa ggcgaatacg attgatttgt acaacgacca attcattgtt
     9721 gatatctaca gaaaaagaca gtaaaatagc attaaaaact tgaccaaacg cctaaaattc
     9781 ggtactatat agaagtgagt aataactcag aaaattattg gaggacttag caaatggcta
     9841 ataaacaaga tttgattgca aaagttgcag aagcaacttc attgactaaa aaagactcag
     9901 cagcagctgt tgatgcagta ttcggagcag tagcagacta ccttgcagct ggtgaaaaag
     9961 tacaattgat cggtttcggt aactttgaag ttcgtgagcg ttcagcacgt acaggccgca
    10021 accctcaaac aggtgcagaa atcaaaatcg cagcatctaa agtacctgct ttcaaagctg
    10081 gtaaagcact taaagacgct gtaaaataaa acagtctggg gatagactgt tttatccctc
    10141 gcttaaaaac aaaagagcga ggctaagcat caaaaagccc gtcatatcaa gctttctagc
    10201 ttgtccgacg ggcttttttt ctactatttg tcaagtccat caaggtattt gacgaaaaat
    10261 attttgagtt caatagtcaa aataaggaaa ttgttttatt ttggactaca ttttagtgta
    10321 aaaagtgcat acaaaaccaa caccttatgt tgaaattttt t
//
LOCUS       DBNFCO010000062        10074 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.062, whole genome shotgun sequence.
ACCESSION   DBNFCO010000062 DBNFCO010000000
VERSION     DBNFCO010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10074
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.062"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(<1..246)
                     /locus_tag="AC1PIV_001493"
     CDS             complement(<1..246)
                     /locus_tag="AC1PIV_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HIP6612507.1"
                     /translation="MDVLYQSCAGIDVHQANIVVCILHGPLTSTRPKREMATFDTTTK
                     GLRACHDFLSQFHVEAVGMESTGVYWRPVWHALCDDFE"
     gene            complement(651..1550)
                     /locus_tag="AC1PIV_001494"
     CDS             complement(651..1550)
                     /locus_tag="AC1PIV_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012774888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIP6612508.1"
                     /translation="MNDKEFGQRVRQLRESASMTREQFCDDELELSVRQLTRIEAGAS
                     KPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLKFDVLRTPTYGNEDLAEKRDAMM
                     TEIYDDYYDELPEEEKIAIDAIQSRIDTLESGTAGFGKEILEDYFEQIFRKRKYELND
                     LLIVRLHLEYVRLSSCDSEIFRQFLKIIEHLHEQINIINSNDLFVLRDTLLSCVNILG
                     SKKYYEPIPKIFDSVDKIIQSTQDFQKKPIVSVLKWKYALFVDKDRDEAEKHYLDAVL
                     FAKLIENRELEQKIEEDWRVDNQ"
     gene            complement(1797..2432)
                     /locus_tag="AC1PIV_001495"
     CDS             complement(1797..2432)
                     /locus_tag="AC1PIV_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HIP6612509.1"
                     /translation="MTPTFIWDLDGTLLDSYEAILAGIQETYQEYVLPFDRAEVRKFI
                     LRYSVKDLLVRDADKYGLDSDELNRVRATSLKEKNTQIPLMAGAVEILNWTAEQGIQN
                     FVYTHKSDNAFQVLEDLGVRHHFTEILTSDSGFARKPSPEALLFLIEKYGLDKENTYY
                     IGDRLLDVETAVNAGIHSINLQIDGVEQNWKIVSLLDIKQILTDKSSHNNL"
     gene            complement(2434..3180)
                     /locus_tag="AC1PIV_001496"
     CDS             complement(2434..3180)
                     /locus_tag="AC1PIV_001496"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIP6612510.1"
                     /translation="MAEQMRQAARLFGDWPETIIWTCLEGVMGDIYVDDSQLPQSALA
                     LYGRQSFFGFLAGQPHRDLLKICEGKDMILVPQNQNWSDLIEGTYGDGIRSFTRYATK
                     KDTEFDLGHLQKLVDDLPESFDMKRIDRNLYEACLVEEWSRDLVGNYIDVEQFLDLGL
                     GYVILHKGQVVSGASSYASYSAGIEIEVDTREDYRGLGLAKACAAQLILACLDRGLYP
                     SWDAHTLTSLKLAEKLGYQLDKPYQAYEWR"
     gene            complement(3180..4181)
                     /gene="ruvB"
                     /locus_tag="AC1PIV_001497"
     CDS             complement(3180..4181)
                     /gene="ruvB"
                     /locus_tag="AC1PIV_001497"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HIP6612511.1"
                     /translation="MTNRILDMEQMQDEEYVERTLRPQKLNEYIGQDKVKDQLKIFIE
                     AVKLRDEALDHTLLFGPPGLGKTTMAFVIANELGVNIKQTSGPVIEKAGDLVALLNDL
                     EPGDVLFIDEIHRMPMAVEEILYSAMEDFYIDIMIGAGEASRSVHLELPPFTLIGATT
                     RAGMLSNPLRARFGITGHMEYYELADLTEIVERTADIFDMEITHEAAIELARRSRGTP
                     RIANRLLKRVRDFAQIMGDGLIDDSITDKALTMLDVDREGLDYVDQKILRTMIEMYGG
                     GPVGLNTLSVNIAEERETVEDMYEPYLIQQGFLMRTRTGRVATAKAYEHLGYPYTEK"
     gene            complement(4476..4649)
                     /locus_tag="AC1PIV_001498"
     CDS             complement(4476..4649)
                     /locus_tag="AC1PIV_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612512.1"
                     /translation="MKQTTYTLSLGGSDRENSRVSKMEEKFEKYMEGIAERLQQSGKK
                     RIDKWFVHVRIEE"
     gene            complement(4751..6463)
                     /locus_tag="AC1PIV_001499"
     CDS             complement(4751..6463)
                     /locus_tag="AC1PIV_001499"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIP6612513.1"
                     /translation="MNKRLVGVLLKSLNKTMFLFGIVLSALGVGMGLFLPQFIGKLLD
                     QTYLSNLLTRPELLAGFILFFVSVYAVQALSNYFIGRSGSNALKQLQQYIYESLLTTS
                     VKDLDQYQSGDLASRLTNDMSVVLNFITVILPNFLMNGLMVMGSIYFLWTISPWLTGL
                     SLFLLPLLSMVMIPMNQRLEGYYSAYQEGLGQVSSRISHKFTTIRLMKAFQGEKHEQR
                     EMGKSFQYLSQTFEKMIGLSAVQHTLVSSLMTGFIILMLLIAGIEVTKGVMTMATLTT
                     FVLYMMQLIDPVTDIAASLNELTEFHAVSKRLVELLELNKEEQVDTELVDATSIQLEK
                     VRFSYHTDPILNGVSVRIPEGAHVAIVGPSGAGKSTIFALLMKYYQDYKGKIRIGQQC
                     LSDISTKEMRRLISFIPQDNTLFHGTIRENLLYGKNESVSEERIAYILKELGLSPLVA
                     ELEDGLDTRISENGTGLSEGQKQRFSIARALLLEHPIYLLDEATASLDTVTERVISKA
                     IDRLTAGKTRLTIAHRLHTVREADAILVLDKNGQVADYGHHQQLVERNHLYQDFLRGL
                     PQAS"
     gene            complement(6466..7239)
                     /locus_tag="AC1PIV_001500"
     CDS             complement(6466..7239)
                     /locus_tag="AC1PIV_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612514.1"
                     /translation="MKQIFPAVFRTIWKRKETQVYLLFTLFPFIYLVTSFIEGSNFMQ
                     IHAGEGYKVSLVAFTNMMVSSADSFILPSLTLYFLAISVFRKEVDEHTMFLYRDLGRK
                     QIFWSKYLGLLATIVIFYGLFFVTSAFVHYVRVIHLPFGSPAVFEASLAESLSNVFCI
                     VAYLLKDILSISLATALCLYLKNITTMITGFLVTITMMILAIVGGPVAMLFPTSYMTL
                     ASEGLTGAGLAYLGAICVTIIYVLVFTKIAAKKFKNLEF"
     gene            complement(7245..8117)
                     /locus_tag="AC1PIV_001501"
     CDS             complement(7245..8117)
                     /locus_tag="AC1PIV_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIP6612515.1"
                     /translation="MLKINHLSKQFAGNEFYSLKDVSLEINKGEIVGLIGKNGAGKST
                     LMKLMAKSLKPSSGTITYKGTDIFSQDNLLADFGIMIDPVFYPEMTVMDNLKFYLDLH
                     GKKDLYPNIEKTLKLVELWDARNRKPKGFSFGMKQRTALAIALVAEPDFLILDEPFVG
                     LDPIGVQKLIDILKQWSSERQISMLISSHQLGELEALCSRYVYIESGELADAFEGKSH
                     PSVLVQLDTTKNLDSVKDLLNDHVVLEGEVLEISTATPTSELNQIFGVLTRQELIVKL
                     EVKENHLKEIFTKG"
     gene            complement(8110..8538)
                     /locus_tag="AC1PIV_001502"
     CDS             complement(8110..8538)
                     /locus_tag="AC1PIV_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Msa family membrane protein"
                     /protein_id="HIP6612516.1"
                     /translation="MIFILLLSLFYICLTVASSQLLLSLSVPVLLLLTYLLPPIVNSI
                     CMGLQKDKSWKAWSAGIFPTMSMIFYAAFAYITSSNGQWEQFAQLHTVSDDVMSVELA
                     GELLVPSQMLFVAVLYYGTAIATYFIQQAGRKKEKGATYA"
     gene            complement(8553..9131)
                     /locus_tag="AC1PIV_001503"
     CDS             complement(8553..9131)
                     /locus_tag="AC1PIV_001503"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamic
                     endopeptidase"
                     /protein_id="HIP6612517.1"
                     /translation="MVVRYMRPVALSLALIVLASISYLLATSLVLFSSSQFLQLAYLF
                     SIMVGMPIGFILLPSMITKRYQLCQELSEVKFSWKSFVLLAIAIFLVNFWFIQSDEYV
                     NQFIIATCEEFLFRYLIYRILKSEYPTWLAMLVTSLLFGVLLHMNYSLLDNLIIRTPL
                     GLLFSVLATRFGLQYAIGGHWIYNLLVSRFPF"
     gene            complement(9141..9869)
                     /locus_tag="AC1PIV_001504"
     CDS             complement(9141..9869)
                     /locus_tag="AC1PIV_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid transporter"
                     /protein_id="HIP6612518.1"
                     /translation="MNMFRSIFKSVIHRRDVALFYAFAGLPILVPILSKFLVGVKAEY
                     TDNFLDFLGAALATQDGIVLPVLLLSLIISAVFRDEIDSGILFLYKDLNRTRLFNAKI
                     ISLVVMYASYVLLTVLTSAIAYFGFLNASGKVVSDDWSNVQSTFLSIFATISINVIGI
                     LLVSTVSIKAKSLQAVLAGVFWSLFTTTAPLLIGVRYVVPNGYAKMSLDQPLLAWSLV
                     VAITTFYTVATYLKGRSNFEKLEF"
BASE COUNT         3115 a         2361 c         1774 g         2824 t
ORIGIN      
        1 ctcgaagtca tcacagagag catgccagac aggtcgccaa tagacaccgg tgctttccat
       61 accaacagct tccacatgaa attgactgag aaaatcgtgg caagcacgta ggcctttagt
      121 cgttgtatca aatgtagcca tctcacgctt tggacgagtt gaggtgagtg gtccatgtag
      181 gatacagaca acaatattgg cttgatggac atcaatacct gcacaagatt gatagagaac
      241 atccatgata attccctcct tctaaaaatt agagagctta tctaccgaat tttagtcgta
      301 tttttatact catgcctgtc gcatattttg gggtgctcgt cagtagagtg agttagtttt
      361 tcccgcgatg actaacatca ttaactcgtt aaccacaaag ccctcactaa gattatacac
      421 ctagtgaggg ctttatgttc gttttcatta ttctgtgggt gagggcggag ccatcatgga
      481 tgtctttccc gctccctttt taataatatt attcttcaac ccatgttccc cagttaccgc
      541 caagacgacc aaaaaatttc aaatagttaa acatgttact aatctccttt aatctttatg
      601 agtttagtat aatgcatttc acaattcttc aacaggacaa aaatgtcact ttattgattg
      661 tcaactctcc aatcttcttc aatcttctgt tctaactctc tattttctat caattttgca
      721 aatagcaccg catctagata atgcttttct gcctcatccc gatccttatc cacaaaaagt
      781 gcatatttcc attttaatac actaacaatg ggctttttct gaaaatcttg tgtcgactgt
      841 ataatcttat ctacactgtc aaatatcttt ggtattggtt cgtaatattt tttacttcct
      901 aatatattta cacaagataa tagcgtgtct cgtaaaacaa ataaatcatt tgagttgatg
      961 atattgattt gctcatgtaa atgctctata attttcaaaa actgtctaaa tatttctgaa
     1021 tcacagctag ataacctaac atattcaaga tggagcctaa caatcaacaa atcattcaat
     1081 tcatactttc gtttgcgaaa aatttgttca aagtagtctt ccagtatctc ttttccaaag
     1141 cctgctgtac ctgactctaa agtatcaatt cgtgattgaa tcgcatctat tgctatcttc
     1201 tcctcctcag gcaattcatc ataataatcg tcatagattt ctgtcatcat ggcatctcgc
     1261 ttttccgcca aatcttcatt accataagtt ggggtgcgaa gcacatcaaa cttcagcttg
     1321 gaatatcttt cgggtaaaga tacataatct ggcataagct cgtaaagtcc catacctaaa
     1381 cgagttgcaa tatactgaat ctttgaaaaa gtcggcttgg aagcacctgc ttcaatacga
     1441 gttaattggc gcacagagag ttccagttca tcgtcacaaa actgttcacg tgtcatacta
     1501 gcagattctc gtaattgacg tacacgctgt ccaaattcct tatcgttcat aaaccacacc
     1561 tccaaatata ctttttaaat tatatcaaat atattacaca aattccatat catgctcttc
     1621 ttaaaacaga cggttggact catttttatt atagcttgaa gccataacaa aacaaaagcc
     1681 cgatgttacg ggcattagtc aagtaatcat agcactaacc tgaacgaagt tcagcggaca
     1741 tctttagacg tcgctggaga gaaacagctt atagctggtg tacaagccac ccgttttcac
     1801 aggttgttat gacttgattt atctgttaat atttgtttta tgtccaataa agaaacaatc
     1861 ttccaattct gctccacacc atcaatttgc aggttgatac tgtgaattcc tgcgttgaca
     1921 gctgtttcta catcgagcaa acggtcaccg atatagtagg tattttcctt gtccagtccg
     1981 tatttttcga tgagaaatag cagagcttct ggacttggtt tgcgggcaaa accagaatcg
     2041 ctggtcaaga tttctgtgaa atggtgacgg acacccaaat cctccaagac ctgaaaagca
     2101 ttgtcactct tgtgggtata gacaaagttt tgaatacctt gttccgcagt ccagtttaag
     2161 atttccaccg caccagccat caagggaatc tgcgtattct tttccttcaa ggaagtcgca
     2221 cgcacacgat tgagctcatc gctatccaga ccgtacttgt ccgcatcacg caccagcaaa
     2281 tccttgacag aatagcgaag gataaacttt cttacttctg cacggtcaaa gggaagaaca
     2341 tattcttgat aggtttcttg aatccctgcc aaaatcgctt cataggaatc caacagcgtt
     2401 ccgtccaaat cccaaataaa tgtcggtgtc atcttatctc cattcgtatg cttgataggg
     2461 cttgtccaat tggtagccca gcttttcagc cagtttcaag gatgtcaagg tgtgggcatc
     2521 ccagctagga tagagaccgc ggtctaaaca agctaaaatt aactgagccg cacaggcttt
     2581 tgccaaaccc agacctcgat agtcttccct ggtatccact tctatctcaa tcccagctga
     2641 atagctggca taggacgaag cccctgagac cacctgcccc ttgtgcaaga tgacatagcc
     2701 cagccccaag tccaaaaatt gttccacatc tatataattt cccaccaaat cccgtgacca
     2761 ttcctctacc agacaagcct cgtacagatt acggtcaatc cgtttcatat caaagctttc
     2821 aggcaagtca tcaaccagtt tctgtaaatg cccaaggtca aactcagtgt cctttttcgt
     2881 agcatagcgg gtaaaggacc gaatcccgtc tccgtaagtc ccttctatca agtcagacca
     2941 gttttggttt tgagggacta gaatcatatc cttaccttcg cagattttta gcaagtctcg
     3001 atgtggctgg ccagctaaaa aaccaaagaa gctctgccgt ccgtagagtg ctagggctga
     3061 ctggggcaac tggctgtcat caacataaat gtctcccatg acaccttcta aacaggtcca
     3121 gataatcgtc tcaggccagt ctccaaataa acgagctgct tgtctcatct gctctgccat
     3181 tatttttccg tatagggata acccaagtgc tcgtaagcct tggctgtcgc aacccgccct
     3241 gtccgcgtcc gcatgaggaa gccctgctga atcaggtaag gttcgtacat gtcctccacc
     3301 gtctcacgct cctcggcaat attgaccgac agggtgttga ggccgacggg accgccaccg
     3361 tacatctcaa tcatggtgcg gagaatcttc tggtccacat agtccagccc ctctcggtcc
     3421 acatccagca tagtcagggc cttatccgta atgctatcgt caatcaggcc gtcgcccata
     3481 atctgtgcga aatcccgcac ccgcttgagc agacggttgg cgatacgggg agttccacga
     3541 gaccgacgag ccagctcaat agcagcttca tgagtaatct ccatgtcaaa gatatccgcc
     3601 gtccgctcga caatctccgt caaatcagcc agttcgtaat actccatgtg accggtaatc
     3661 ccaaatcggg cccgcagggg attggacagc atacccgcac gagtggtcgc tccaatcagg
     3721 gtaaaaggcg gcaactccaa atgcacggag cgactggcct ccccagcccc aatcatgatg
     3781 tcgatgtaga agtcttccat ggctgagtag agaatctcct cgaccgccat gggcatacgg
     3841 tggatttcat cgataaagag gacgtcgcca ggctccaagt cgttgagaag ggccaccaag
     3901 tcacctgctt tttcaataac aggaccacta gtctgcttga tattaacgcc cagttcgttg
     3961 gcgatgacaa aggccatggt ggtcttcccc aaacctggag gtccaaacag aagggtatgg
     4021 tccaaggctt catcacggag cttgactgcc tcgataaaga ttttgagctg gtccttaacc
     4081 ttgtcctgac cgatgtattc gtttaatttc tgcggacgca gggtacgctc gacatattcc
     4141 tcgtcctgca tttgttccat atctaaaatt cgatttgtca tgaaaccatt atagcataaa
     4201 atgaaaatac cagactcagt gagtccagta ttctcaggag attatataat ccctagtcct
     4261 tgtcgcttgc gacttagaga taaggattga aaagatatgc cagccgtttg agctttagct
     4321 cttacggatg acgatattga aactatttca gtaaaagtct cgctatttct agcttgaata
     4381 aagtataact cgccaaactt aagggaaact aaaagagaat tcattctatt tttcactatt
     4441 tataaaaacg tctgtgaatt ttggtcatag ctactttact cctcaattcg cacatgaaca
     4501 aaccatttgt caattcgctt cttcccagat tgctgtaacc gctctgcgat tccctccata
     4561 tatttttcaa acttttcttc catcttcgaa actctggagt tctctctgtc acttcctccc
     4621 aaagataagg tatatgttgt ttgtttcatt ctcttctcct atctattcat tgtacaagta
     4681 atcatcagta ttccatttta ttattaggta accctagact tagactggtc ggtccattga
     4741 ctcccattca ctaactggct tgcggtaagc ctcttaagaa atcttgatac agatgatttc
     4801 tctccactaa ctgctggtga tgaccgtagt cagctacttg tccattttta tctaaaacca
     4861 aaatagcatc tgcctcacgc accgtatgca aacggtgagc aatggttagc cttgttttgc
     4921 cagctgttaa tcggtcaatc gctttgctaa tgacacgttc tgtgacagta tctaaacttg
     4981 ctgtcgcctc atctagcaaa taaatcggat gttctagcag taaggctctt gcaatgctga
     5041 accgttgttt ttggccttcc gacaagcctg tcccattttc tgaaatccga gtatctaaac
     5101 catcttccaa ctcagctact aaaggagaca atcccaactc cttgagaata taagcaatac
     5161 gctcttcaga cacagactcg ttctttccat acaatagatt ttctctaatc gtcccatgaa
     5221 agagagtatt gtcctgaggt atgaaggaaa tcaatcttct catctccttg gttgaaatat
     5281 cacttaaaca ttgttgacca atccgaatct tccccttata gtcttgataa tatttcatca
     5341 gcaaggcaaa aatcgttgac tttccggctc cgcttggccc aacaatcgcc acgtgagctc
     5401 cctcaggaat tctaaccgat actccattca aaatcggatc tgtatgatag gaaaaccgaa
     5461 ctttttccaa ctggatacta gtagcatcaa ccaactctgt atctacctgt tcttccttat
     5521 tcagttccag caattctacc aaacgtttag acactgcatg aaactccgtc agttcattta
     5581 gggaagcagc aatgtctgtg actggatcaa tcagttgcat catgtacaat acaaaggttg
     5641 tcaatgtagc catggtcatc actcccttgg ttacttctat ccccgctata agcaacatca
     5701 ggataataaa tcccgtcatt aagctactaa ccaaggtatg ttgcaccgct gacagtccaa
     5761 tcattttctc aaaggtttgt gacagatact gaaaagactt gcccatctct cgctgttcat
     5821 gcttttctcc ctgaaaagcc ttcatcaaac gaatcgttgt aaatttatga ctaattctac
     5881 tagaaacctg ccctaatccc tcttggtaag cagagtagta accttccaac cgctgattca
     5941 tcggaatcat aaccattgac aacaaaggaa gcaagaagag actaagaccc gtgagccacg
     6001 gactgatggt ccacagaaaa taaattgacc ccataaccat caaaccattc atcaagaaat
     6061 ttggaagaat aacggtgatg aagttcagaa caaccgacat atcattagtc aaacgactag
     6121 caagatcacc tgattggtac tgatccaagt cctttacaga tgtggtcaac aaggattcat
     6181 aaatatattg ttgcaactgt ttgagtgcat tactaccact acgccctatg aaataattag
     6241 atagagcctg tactgcatag accgatacaa agaaaaggat gaaacctgcc agcaattctg
     6301 gccgtgttaa tagattgctc aaataggttt gatctagcaa tttaccaata aactggggca
     6361 ggaacaaacc cattccaacc ccaagtgcac tcagaactat cccaaacaag aacatcgttt
     6421 tattgagcga cttcaacaac actccgacga gtcttttatt cataactaga actccaaatt
     6481 cttgaatttt ttcgcagcaa ttttagtaaa tacgagtacg taaataattg tgacacagat
     6541 agctcctaaa taagcaagcc ccgctcctgt caggccttcg ctcgccaaag tcatataact
     6601 agttggaaaa agcatcgcaa ctggaccgcc aacaattgct aaaatcatca tcgtaatcgt
     6661 caccaaaaat cctgtgatca ttgtggtaat atttttcaga tacaaacaaa gagcagttgc
     6721 caaactaatc gataaaatat cttttagcaa ataagcgaca atacaaaata cattactcaa
     6781 gctctctgcc aaactagctt caaaaacagc tggactacca aaaggtagat ggattacccg
     6841 aacataatgt acaaatgcag aggttacaaa gaagagacca tagaaaatga cgattgttgc
     6901 taagagaccc aaatatttag accagaaaat ctgcttccgt ccaagatccc ggtataaaaa
     6961 catggtatgt tcatctactt ctttcctaaa gacagatata gccaagaaat acagggtcaa
     7021 actaggaaga atgaaactat ctgctgagct caccatcata ttcgtaaagg caacaaggct
     7081 gactttatag ccctcaccag catgaatctg cataaaattc gacccttcaa taaacgaagt
     7141 aactagataa ataaaaggaa acaaagtgaa taggagataa acctgcgtct cctttcgctt
     7201 ccaaatcgtt ctaaagacag ctggaaaaat ttgcttcata ctcactaccc tttcgtaaag
     7261 atttctttca agtgattctc tttcacttct agtttcacaa tcaattcttg acgagtcaac
     7321 acaccaaaaa tctgatttag ctcacttgta ggtgtggcag tggaaatctc taacacttcc
     7381 ccctctagca ccacatggtc attgagcaag tccttcacag aatctaagtt tttagtcgtg
     7441 tccaactgca cgagcacact tggatgagat ttgccttcaa aagcatctgc caattctccc
     7501 gattcgatat agacatagcg gctgcacaag gcctccagct cacctagttg gtgactcgaa
     7561 atcagcatgg aaatttgtcg ctcactggac cactgcttca agatatcaat caatttttga
     7621 acaccaatcg ggtccaagcc cacaaaaggc tcatctaaga tcaggaaatc tggctccgca
     7681 accaaggcaa tcgccaaagc tgtccgttgt ttcataccga acgagaatcc cttgggtttc
     7741 cgattgcgag catcccataa ctctaccaat ttcaaagtct tctcaatatt tggatagagg
     7801 tcttttttcc catgcaggtc caaataaaac ttgagattgt ccataacagt catttctgga
     7861 tagaatactg gatcaatcat aatcccaaag tctgctaaca aattatcctg gctaaaaata
     7921 tccgtaccct tataagtaat ggttcccgaa cttggtttta gggacttggc catgagtttc
     7981 ataagcgtgg attttccagc accgtttttt ccaatcagac caacaatctc gcccttattg
     8041 atctccaaac tcacatcttt tagtgagtaa aattcatttc ctgcaaactg ttttgataaa
     8101 tgattgattt taagcataag tagctccttt ttctttctta cgacctgcct gctgaataaa
     8161 ataagtggca atagctgtac cataatatag tacggcaaca aatagcattt gtgatggaac
     8221 taacaattct cctgccagct cgacactcat gacatcatct gaaactgtat gcagttgagc
     8281 aaactgctcc cactgaccat tgctactcgt aatgtaggca aaagcggcat aaaatatcat
     8341 tgacattgtt gggaaaatgc ctgctgacca cgctttccaa gacttatctt tttgtaatcc
     8401 catacagatt gaattgacga tgggcggtag caaataagtc aacaacaata aaacaggaac
     8461 agagagactt agcaatagtt gcgaactagc aactgttaaa caaatataaa atagactcaa
     8521 taatagaata aatatcatca tgaccctcac aattaaaatg gaaatctcga aaccaacaga
     8581 ttgtagatcc aatgtcctcc gatagcatac tgcaagccaa aacgagtagc taacacagaa
     8641 aacaataaac ctagtggagt tcggatgatt agattatcca gcaaggaata attcatatgc
     8701 aacaaaactc caaacaagag agaagtgacc aacatagcta gccaagtagg atattcactt
     8761 tttagaatac gatagataag ataacggaac aagaattctt cacaagtcgc aataataaat
     8821 tgattcacat actcatcact ctgaataaac cagaaattga ccaagaaaat tgcaatagcc
     8881 agcaaaacaa agcttttcca actgaacttc acttccgata gctcctgaca aagctgataa
     8941 cgcttggtta tcatagatgg aagtagaata aaccctattg gcattccaac cataatagaa
     9001 aataggtagg ctagctgtag aaattgacta gagctaaaca aaaccaaaga tgttgccaaa
     9061 agataactaa tggaggctaa aacaatcaaa gcaagcgata aagcaactgg cctcatatag
     9121 cgcactacca taaaacacct ctaaaattct agcttttcaa agttcgaacg acctttgaga
     9181 taggtagcaa cagtataaaa tgtcgttata gctactacca aggaccatgc aagcagtggc
     9241 tgatcaagac tcatcttagc atagccattc ggcacaacat aacgaactcc aatgagaagt
     9301 ggtgcagttg ttgtaaacag tgaccaaaaa actcctgcta aaactgcctg taaggatttg
     9361 gctttgatag aaaccgtaga aaccaataaa ataccgataa cattgattga aattgttgca
     9421 aaaatagata ggaaagtgga ctgtacatta ctccaatcat ccgatactac ttttccagaa
     9481 gcattcaaga agccaaaata agcaatcgca cttgtcagca ctgttagaag gacataagag
     9541 gcatacatca ccactaaact aatgattttt gcattaaaaa gtcgggttct attcagatct
     9601 ttatataaaa atagaatgcc actatcaatc tcgtccctaa agactgctga aataatcaag
     9661 gataacagta atacaggtaa cactatcccg tcctgtgttg ccaatgctgc tcctagaaaa
     9721 tctaaaaaat tatccgtata ttcagccttt acgcctacca aaaatttgga caatatagga
     9781 actaagattg gcaaacccgc aaaagcatag aacaaagcaa catcccttcg atgtatcacc
     9841 gacttaaaaa ttgacctaaa catattcata ttgtttcccc tttttatcaa taagatagga
     9901 actgtaacaa attcccatct tattgatagc taaatcaaat tagctatcaa gttcttttta
     9961 caaagtgtga cgaccgcggc gataagtgta tttgatgata cctaaatcaa tagtgatgcg
    10021 cttattcttc ttaaataatt gtttcatttt tactcctttt tctttaaaaa ttta
//
LOCUS       DBNFCO010000063         9718 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.063, whole genome shotgun sequence.
ACCESSION   DBNFCO010000063 DBNFCO010000000
VERSION     DBNFCO010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9718)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9718)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9718
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.063"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            52..549
                     /locus_tag="AC1PIV_001505"
     CDS             52..549
                     /locus_tag="AC1PIV_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HIP6612519.1"
                     /translation="MEKKIFQLLEWMASKTGQLVMGSFILLSVVTFSIFTIWDIAAAP
                     FNNARSHAVGVATEYADLQTVNDFSIYNGTETYFCVFGVTSQGEEVAVLIPEASSTVY
                     VYSLAQGISQEEAQAIAKKNGASQVERTILGLRDGKPIWEVKSGTAYYLVEFETGNFI
                     KREGL"
     gene            546..1727
                     /locus_tag="AC1PIV_001506"
     CDS             546..1727
                     /locus_tag="AC1PIV_001506"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002267262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HIP6612520.1"
                     /translation="MSKLSKRVLEMEESVTLAAGARAKALKAEGRDILELTLGEPDFV
                     TPKNIQEAAIKSIEDGKASFYTVASGLPELKDAVNTYFENFYGYSIERNQVVLATGAK
                     FILYAFFAAVINPGDEVLIPTPYWVSYADQIKMNDGVPVFVTASEEHNFKVTVDQLEA
                     ARTDKTKVFLLNTPSNPTGMIYSREELEAIGNWAVEHDILILADDIYGRLVYNGNTFT
                     PISSISESIRQQTIVVNGVAKAYAMTGWRVGFAVGNPEIIAAMSKIVGQTTSNLTTAA
                     QYAAIEAFTGPQDTVETMRQAFEERLNTIYPLLAEVPGFEVIKPEGAFYLFPNVKKAM
                     EMKGYTDVTEFTTAILEEVGVAMVTGAGFGAPENIRLSYATDMDTLKEAVARLHTFMK
                     K"
     gene            1742..3088
                     /gene="asnS"
                     /locus_tag="AC1PIV_001507"
     CDS             1742..3088
                     /gene="asnS"
                     /locus_tag="AC1PIV_001507"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004816 - asparagine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006421 - asparaginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HIP6612521.1"
                     /translation="MSRKLITINQVKDYVGQEVTIGAWVANKSGKGKLAFLQLRDGTA
                     FFQAVAFKPNFIEKFGEEAGTEKFDVAKRLSQETSVYVTGIVKEDERSKFGYELDVTD
                     LEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAIQQIRNAIIYATYEFFEKNGF
                     IKFDSPILSGNAAEDSTELFETDYFGQLAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSFLSHEESLDLQEAYVKALIQGVIDRAPQALETLERDVD
                     ALKRYIAEPFKRVAYDDAITLLQEHEADKDTDYEHIEHGDDFGSPHETWISNYFGVPT
                     FVVNYPASFKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREDNYDALVAKMDEL
                     GMDKSEYEFYLDLRKYGSVPHGGFGIGIERMVTFVAGTKHIREAIPFPRMLHRLHP"
     gene            3360..3587
                     /gene="relB"
                     /locus_tag="AC1PIV_001508"
     CDS             3360..3587
                     /gene="relB"
                     /locus_tag="AC1PIV_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HIP6612522.1"
                     /translation="MGIVSLRLNDAEEEIFRSYAIHTGKSLSELFKTALAEQIEDQLD
                     YEIGIKALKKFQENPVTHSIDDVLAELEDGL"
     gene            3577..3846
                     /locus_tag="AC1PIV_001509"
     CDS             3577..3846
                     /locus_tag="AC1PIV_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0004521 - RNA endonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE family
                     toxin"
                     /protein_id="HIP6612523.1"
                     /translation="MAYKLVLSDDALKQLKKMDRHVGMMLAKDLKKRLDGLENPRQFG
                     KALVGDYKGLWRYRVGNYRVICDIIDNKMVILALEIGHRKEIYKK"
     gene            4252..5571
                     /locus_tag="AC1PIV_001510"
     CDS             4252..5571
                     /locus_tag="AC1PIV_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HIP6612524.1"
                     /translation="MKQESLGKEIIRLALPATVENIFQTLVGFVDTLLIAQLGLVAVT
                     AVGLANTILNVYLAVYMALGVGATALIARSIGAGDRESLTFHVRQALVLSVGVGLLLG
                     LLSLVFGRQMLVLMGADAESLAGVQVFFYWVGGLTIFQALMTILGTILRASGDTVFPM
                     KMSLLTNGFNVVLDYFLIFGIGSWSGLGIVGTALGTVLARLLGTVLLYRKVQQTDLAV
                     DLKQLFHLGSPKEMVVLTLPAATERLVMRLGQVVYFSLIVGLGTIVYASHMIAGNIES
                     FTYMPAYGLATAAAVLIGQALGKGDILTVRRVAFLSSAYGVAIMSLLGTILFFGAPSF
                     ALLFTKDLEAVRQVVTALRIDAFNQPGLAVSLIMAGALQGLGDTKSPLYSTMIGMWGL
                     RVSGVIVLGQMFGLGIAGVWLSILIDLLLRAIFLTWRFIVQTRKLAE"
     gene            5622..5999
                     /locus_tag="AC1PIV_001511"
     CDS             5622..5999
                     /locus_tag="AC1PIV_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HIP6612525.1"
                     /translation="MKTIHTDKAPAAIGPYVQGKVVGNFLFASGQVPLSPETGEVVGE
                     TIQEQTEQVLKNIAAILSEAGTDFDHVVKTTCFLKDMNDFVAFNEVYKTAFSADFPAR
                     SAVEVARLPRDVKVEIEVIAVID"
     gene            6021..6908
                     /gene="rapZ"
                     /locus_tag="AC1PIV_001512"
     CDS             6021..6908
                     /gene="rapZ"
                     /locus_tag="AC1PIV_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HIP6612526.1"
                     /translation="MSDKLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPTLLPKF
                     LELIRHSQDNNKIALVVDMRSRSFFSEIREVLDEIEGAEDLDFKVLFLDATDSELVAR
                     YKETRRSHPLAADGRVLDGIQLERELLAPLKNMSQNVIDTTELTPRNLRKVISEQFAS
                     QDNQPSFRIEVMSFGFKYGLPLDADLVFDVRFLPNPYYKLELRNLTGLDAPVFDYVME
                     HQESEEFYSHLLGLIEPILPGYQKEGKSVLTIAVGCTGGQHRSVAFAKRLADDLEKNW
                     NVNRSHRDKDRRKETVNRS"
     gene            6905..7879
                     /locus_tag="AC1PIV_001513"
     CDS             6905..7879
                     /locus_tag="AC1PIV_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HIP6612527.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLRDKDVEITAIVTVADDGGSSGE
                     IRQALQVTPPGDLRNVLLAMSDMPKLYEQIFQYRFADSDGPLAGHPLGNLIIAGISEM
                     QGSTYNAMRLLTRFFHTTGRIYPSSEQALTLHAIFTDGTEVAGESKISKHNGMIDHVY
                     VTNSYNDDEPKASRQVVETIMESDMIVLGPGSLFTSILPNLMISDIGKALKETKAEVT
                     YVCNIMTQRGETEFFSDADHVAVLNAHLAEQFIDTVLVNIEPVPQEYMNSNQFDEYLV
                     QVKHDFAGLQKQANRVISSNFLRLENGGAFHDGDLVVEELLKILQVRP"
     gene            7876..8793
                     /gene="whiA"
                     /locus_tag="AC1PIV_001514"
     CDS             7876..8793
                     /gene="whiA"
                     /locus_tag="AC1PIV_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HIP6612528.1"
                     /translation="MSFTVQVKEELLLQSSQNKSELSAIIKLSGSLGLASSGLTLSIS
                     TENAKIARHIYELLLHFYQIKAEIRHHQKPNLKKNRVYAVLIEDGVNEILNDLHLADS
                     FFGLETGISPLVLENDSWSQAYLRGAFLAAGSVKDPEKGKYQLEIASVYSDHANDLAN
                     LMQKFLLDAKVIERSKGTITYLQRAEDIMDFLLVIGAEETKTEFENVKLLREARNDLN
                     RATNAEAANIAKTVNASMKTINNIIKIMDTIGLDQLSGDLQEIAQLRIQHPDYSIQQL
                     ADSLTVPITKSGVNHRLRKINKIADELTD"
     gene            9079..>9718
                     /locus_tag="AC1PIV_001515"
     CDS             9079..>9718
                     /locus_tag="AC1PIV_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002941723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HIP6612529.1"
                     /translation="MISNEQYDYLRAHPTFERLTRDSFDQLAKHIRFRKIPKGQIFFY
                     AEDPRDYLFVLYKGYARIEQYDETDSFTYLDYIRQGGAFPFGDMFQDKPYHYTAIAIT
                     DLEYFIVPMVLFETLSKINPSQMAYICQKLSKVLRFQELRLRNAMRSKASDRVVQALA
                     LLYWDMCQREQFATLPFEIHIQEISRLAATTRETVSHVLKQLKQDGKIAYSHK"
BASE COUNT         2640 a         1838 c         2363 g         2877 t
ORIGIN      
        1 atcacagaaa gaatggaaat atgctttaat ttgtagtata atgggactgt tatggaaaaa
       61 aagatttttc aactgttgga gtggatggct tccaagactg gtcagttagt gatgggctct
      121 tttatccttc tcagtgttgt gactttttca atttttacta tttgggatat tgctgctgcc
      181 cctttcaaca atgcgcgtag tcatgcagtt ggagtagcta cagaatatgc tgatttgcaa
      241 actgtcaatg atttttctat ctacaatggt actgaaacct atttttgtgt atttggtgtc
      301 accagtcagg gagaagaggt tgcagttttg attccagagg cttctagcac agtatatgtc
      361 tattctttag ctcagggaat ttcgcaagaa gaagcgcaag ctattgccaa gaaaaacggt
      421 gcaagccaag tagagcgaac tattctaggt ttaagggatg gcaaacctat ttgggaagtc
      481 aagtcaggta ctgcctacta tttagttgaa tttgaaacag ggaactttat caaacgggag
      541 ggcttatgag caagctatca aaacgtgtct tagaaatgga agaaagtgtc acgctggcag
      601 cgggtgcacg ggcaaaggcc ttgaaggcag aaggacgtga tattttagag ctgaccttgg
      661 gtgagccaga cttcgttaca ccgaaaaata ttcaagaagc tgctattaag tctatcgaag
      721 atggtaaggc gagtttttat acggtagctt caggtctgcc agaattgaag gacgcggtca
      781 atacctactt tgagaacttt tatggctact ctatcgaacg caatcaagtc gttcttgcca
      841 ctggtgccaa gtttatcctt tatgctttct ttgcggcggt catcaatcct ggtgatgagg
      901 ttctgattcc cacaccttac tgggtttctt atgcagatca aatcaagatg aatgatgggg
      961 tgcctgtctt tgtcactgca agtgaagagc acaatttcaa ggtaacagtt gaccagctgg
     1021 aagcagctcg gacagataag accaaagtat tcctactcaa tactccttct aatccgactg
     1081 gcatgattta cagtcgtgag gaattggaag ctattggcaa ctgggctgta gagcacgaca
     1141 ttctcatctt ggcagacgat atttacggtc gtttggtata taatggaaat accttcacac
     1201 cgatttcaag catttcagaa agcattcgtc agcagactat tgttgtcaat ggggtggcca
     1261 aggcctatgc catgacaggt tggcgggttg gatttgccgt tggtaatcct gagatcattg
     1321 cggctatgag taagattgtc ggacaaacga cgtcaaactt aacaaccgct gctcagtatg
     1381 cggccattga agcctttaca ggtccgcaag atacggtcga aaccatgcgt caggcatttg
     1441 aagagcgact caataccatt tatcccttgc tggcagaagt gcctggtttt gaagtgatta
     1501 agccagaagg tgccttctat ctcttcccaa atgtcaaaaa ggctatggaa atgaagggct
     1561 acacagatgt aactgaattt accacagcca ttttggaaga agtgggagtt gcaatggtga
     1621 caggtgctgg ttttggagct cctgagaata tccgcctcag ctatgcgaca gatatggaca
     1681 cgctcaaaga agcagtggct cgactacaca catttatgaa aaaataaaaa gaggaaaaat
     1741 aatgtctaga aaattgatta ccatcaacca agtaaaagat tatgtcggtc aagaagtgac
     1801 cattggtgcc tgggttgcta acaaatcagg caagggcaag ttagccttcc tgcaattgcg
     1861 tgacggaaca gccttcttcc aagcagttgc cttcaaacca aacttcatcg aaaaattcgg
     1921 tgaagaagct ggtactgaga agtttgatgt agcaaaacgc cttagccaag aaacgtctgt
     1981 ctatgtgaca gggattgtca aggaagatga gcgttctaag tttggttatg agttggatgt
     2041 gacagacctt gaagtgattg gtgagtcaca agattaccca atcacaccaa aagaacacgg
     2101 tacggacttc cttatggaca accgtcacct ctggttgcgt tctcgtaaac aggtcgctat
     2161 ccagcaaatc cgtaacgcca tcatctatgc gacttatgaa ttctttgaaa agaatggctt
     2221 tatcaagttt gatagcccaa tcttgtctgg aaatgcggca gaagattcga cagaattgtt
     2281 tgaaacagac tactttggtc agcttgccta cctcagccaa tctggtcagc tttacctgga
     2341 agctggtgcc atggcccttg gtcgtgtttt cgacttcggt cctgttttcc gtgcggaaaa
     2401 atcaaaaact cgccgtcact tgacggagtt ctggatgatg gatgccgagt attcattcct
     2461 cagccatgaa gagtcacttg acttgcaaga agcttatgtc aaagccttga ttcaaggtgt
     2521 tatcgaccgt gctccacaag ccttggaaac tcttgagcgt gatgtggatg ctctcaaacg
     2581 ctacattgca gagccattca aacgtgtggc ttatgatgat gctattaccc ttcttcaaga
     2641 gcatgaagct gataaagata cagactacga acacatcgag catggtgatg actttggatc
     2701 accacatgaa acttggattt caaactactt tggtgtaccg actttcgttg ttaactatcc
     2761 agcaagcttc aaggccttct acatgaagcc agttccaggt aatccagagc gcgtgctttg
     2821 tgcggacctc ttggcaccag aaggctatgg tgaaatcatt ggtggttcta tgcgtgagga
     2881 taactacgat gccttggtag ccaagatgga cgagctcggt atggacaagt cagagtacga
     2941 attttacctt gaccttcgta aatacggttc agtgccacac ggtggtttcg gtatcggtat
     3001 tgagcgtatg gtaaccttcg ttgctggtac aaaacacatc cgtgaagcca ttccattccc
     3061 acgtatgttg caccgcttgc atccgtaata cagtcgttca gtttttcctt tattacgtcg
     3121 acgtatgagg aaactccgtt tccttatttc caagttcaaa taatctcatc attatttgaa
     3181 ctcgttttgc cgtaccttag tacagtctgc agctcgttgc ctagtactaa aagtaaactg
     3241 aaagactgcg aaataaatat tcactgacag actacaaacg tggtctgttt ttctggtgtc
     3301 aattgacatt ttgaacgaat tgttttacaa tgtattacaa gaagaaagta ggtggaatga
     3361 tgggaattgt atccttgcga ttaaacgatg cagaagaaga aattttcaga agctatgcta
     3421 ttcatacagg aaaaagcctg tctgagctat tcaaaactgc acttgctgaa cagatagaag
     3481 accagttgga ctatgaaatt ggtatcaagg ctttgaagaa attccaagaa aatcctgtta
     3541 cacactcgat tgatgatgtt cttgcggagt tagaagatgg cttataagct tgttctcagc
     3601 gatgatgctt tgaagcagtt gaaaaaaatg gacaggcatg tggggatgat gcttgctaag
     3661 gatttgaaaa aacgtttgga cggtttggag aatccaagac aatttgggaa ggccttggta
     3721 ggagactata aggggctgtg gcggtataga gtggggaatt accgtgtaat ttgtgatatt
     3781 attgataaca aaatggtcat cctggccctt gaaatcgggc accggaaaga aatctataaa
     3841 aaatgaagtt ctaggtaact aggctcggta tcggtgtact tctcagagtt cgtgtcaaca
     3901 tctcagcgca gtggttgatt ggctttaaca gtccagtgga gtgaagcagt tctgggaact
     3961 gtttcagccc gagtcttgaa gcagaaaagc taggtaaaaa ggttggagat aaggtttgcg
     4021 aagcaaatct cagcaattcg tgttttccac tccaaatctg acctatacga ctgatgcgaa
     4081 ctttgttcgc cttatctcta acctccaaag gttccctgaa actttggagc tatgcggggg
     4141 tggagagatg aactcctttt tgacttatcg agttcttccc cactccctgt tttctttctt
     4201 tttcactgag ttttatttat aattattcta aataaaatcg tggagaggaa aatgaagcaa
     4261 gaaagtttag gaaaagaaat tattcgtttg gccttgcctg ctacggtgga aaatatcttt
     4321 cagaccttag ttggttttgt ggataccctc ttgattgcac agctggggct ggtagcggtg
     4381 acagcagttg gtcttgccaa tacgattttg aatgtctatt tggcggtcta tatggctttg
     4441 ggagttgggg caacagcttt gattgctcgg tctattggcg caggagatag ggaatctctt
     4501 acctttcatg tccgtcaagc cttagtgctt tcagtaggtg taggtctgct attggggtta
     4561 ctatcccttg ttttcgggcg gcagatgttg gtcttaatgg gagcagatgc ggagagtttg
     4621 gctggcgtcc aggtcttttt ctactgggtt ggtggtttga ctatttttca ggccttgatg
     4681 actattttgg gaacaatcct gcgggcatct ggggatacag tatttcctat gaaaatgagc
     4741 ttactgacca atggttttaa tgtggtcttg gactatttct tgatttttgg tattggctct
     4801 tggtcaggtt tgggtattgt agggaccgcc ttgggaactg tcttagctcg cttgcttggt
     4861 actgtcttgc tttaccgaaa ggtacagcag actgacttgg cagttgatct caaacaattg
     4921 ttccacttgg gaagtcctaa ggaaatggtg gttttgaccc tacctgcagc aaccgaacgc
     4981 ttggttatgc ggttgggaca ggttgtctat ttcagtttga ttgtggggct gggaacgatt
     5041 gtctatgctt ctcatatgat tgcaggtaat atcgagagtt ttacctatat gcctgcctat
     5101 ggtcttgcga cagcggcggc ggttttgatc ggtcaagcct tgggaaaggg ggacatcctc
     5161 acagttagac gggtcgcatt tctcagctct gcctatggag tagccatcat gtccctgctc
     5221 ggtaccatct tatttttcgg agccccaagt tttgctctgc tatttaccaa agacctagaa
     5281 gccgtccgtc aagtcgtcac agccttacgg atcgatgctt tcaaccagcc aggccttgcg
     5341 gtttctttga tcatggctgg cgctctgcag ggcttggggg ataccaagtc gccactctac
     5401 tccacaatga taggaatgtg ggggctgcgc gtctcaggtg ttatcgtctt aggtcagatg
     5461 ttcggtttag gaattgccgg cgtctggctg tcgattttga ttgacctgct cttgcgagcg
     5521 atttttctga cttggaggtt tattgtgcaa acacgaaaac tggctgaata ggctagtttt
     5581 ttggtataat atcagtagaa tgataaaaag gagataatca gatgaaaacc attcacacag
     5641 ataaggcacc tgcagcaatt ggcccatacg ttcaagggaa ggttgttgga aatttcctat
     5701 ttgcctctgg tcaagttcct ttgtcacctg aaactggtga agtggttggt gaaaccattc
     5761 aggagcagac tgagcaagtc ttgaaaaata tcgcagcaat tttatcagaa gcaggaacag
     5821 actttgacca tgtggtgaag acgacttgtt tcctaaaaga tatgaatgat tttgtagcct
     5881 ttaatgaagt ttataaaaca gctttctcag cagattttcc agctcgttca gcggtggaag
     5941 ttgcacgctt gccacgtgat gttaaggttg agattgaagt tattgcagtt attgattaga
     6001 agagaaaagg aggggatgtc atgtcggaca aactccattt agtgattgtg acagggatgt
     6061 cgggagctgg taagacagta gccattcagt cttttgagga cttgggttat tttaccattg
     6121 acaatatgcc accgactctc ttgccaaagt ttttagagtt gattcgtcat agccaggata
     6181 acaataagat tgctcttgtt gtagatatgc ggagtcgatc cttcttctcg gagattcgag
     6241 aggtgttgga tgagattgag ggggcagagg atttagattt taaagtccta ttcttggatg
     6301 cgacggatag tgaattggtt gctcgctata aagaaactcg tcgttcccat cctttggcgg
     6361 ctgatggtcg tgttttggac gggattcagc tagaacgtga acttttggct cccttgaaaa
     6421 atatgagtca gaatgtcatt gatacgacag agctgacacc tcgcaatctc cgtaaggtaa
     6481 tctcagagca gtttgctagt caagataatc agccgtcgtt tcgcatagaa gtgatgtcct
     6541 ttggtttcaa atatggacta cctctggatg cagacttggt ttttgacgtt cggttcttac
     6601 caaatcccta ctacaagttg gagttgcgta atctgactgg tctggatgct cctgtctttg
     6661 actatgtcat ggagcatcaa gaatcggaag agttttatag tcatttgctc ggcttgatag
     6721 aaccgattct tcctggttat cagaaagaag gaaaatcagt tctaacgatt gccgttggat
     6781 gtacgggtgg tcagcataga agcgtagcct ttgctaaacg tttggcagac gatttagaga
     6841 aaaattggaa tgttaatcgt agtcatcgtg ataaggacag acggaaggag acggtcaacc
     6901 gctcatgaga aaaccaaaga ttacagttat cgggggcggg actggtattc cagtcatttt
     6961 gaagagtttg cgggataagg atgtagagat taccgctatc gtgacggtag ctgatgacgg
     7021 aggatcttcg ggggaaatcc gtcaggcttt gcaggtgacc cctccaggtg atttgcgtaa
     7081 cgtcctattg gctatgtcgg atatgcccaa actttatgaa caaattttcc agtatcgttt
     7141 tgcggattca gatggcccct tggctggtca tccactaggg aatctcatca ttgctggtat
     7201 ttcagaaatg cagggttcaa cctacaatgc gatgaggttg ttgacgcgct ttttccatac
     7261 gacagggcgg atttatccat ctagcgaaca ggccttgacc cttcatgcta tttttacaga
     7321 tgggaccgag gtagcaggtg agagtaagat ttccaagcat aatgggatga ttgatcatgt
     7381 ctatgtgaca aattcttata atgatgatga accgaaagcc agtcgccagg tagttgaaac
     7441 gattatggaa agtgacatga ttgtacttgg accgggttct ctttttacct caatcttgcc
     7501 gaatctgatg atttctgaca ttggcaaagc cctaaaagaa accaaggctg aagtgaccta
     7561 tgtgtgcaac attatgaccc aacggggaga gactgagttt ttctcagatg cggaccacgt
     7621 ggcggttctc aatgcacact tagctgaaca attcattgat acagttttgg tcaatattga
     7681 gccagttcca caagagtata tgaatagcaa ccagtttgat gaatacttgg tacaggtaaa
     7741 acacgatttt gcaggtttgc aaaaacaagc taatcgtgtg atttcttcga attttcttcg
     7801 tttggaaaat ggcggagctt tccatgatgg tgacttggta gtagaagagt tgctcaagat
     7861 tttgcaggtg cggccatgag ttttacagta caagtaaagg aagaattgct gcttcagtct
     7921 agccaaaata agagcgagct atctgctatt atcaaattat caggtagttt gggcttagct
     7981 tcatcaggtt tgactctttc tatcagcacg gaaaatgcaa agattgcccg tcacatttat
     8041 gaactgttac tccatttcta ccagattaaa gctgagattc gccatcatca aaaacctaat
     8101 ctcaaaaaga atcgtgtgta tgcagttttg atagaagacg gcgtgaatga gatattgaac
     8161 gatttgcatt tggctgatag cttctttgga ttagagacgg ggatttctcc cttggttttg
     8221 gaaaatgatt cgtggagtca agcctatctt cgtggagcat ttttagcggc aggctctgtt
     8281 aaggatcctg aaaaaggaaa ataccagctt gaaatagctt ctgtctatag tgaccatgcc
     8341 aatgacctgg ccaatctgat gcagaaattt cttttggatg ccaaagtcat tgagcgaagt
     8401 aagggaacca ttacctatct gcaacgtgca gaggacatta tggattttct tttggtgatt
     8461 ggagcagaag agacgaagac agaatttgag aatgttaaat tgcttcgtga ggctcgcaat
     8521 gacctaaatc gagctaccaa tgcggaagct gctaatattg caaagacggt caatgctagt
     8581 atgaaaacaa tcaataatat tatcaaaatt atggatacta tcggtctaga tcagttgtca
     8641 ggtgacttgc aggagattgc ccagttgcga attcagcatc cagactattc cattcagcaa
     8701 ttggcggata gtctaacggt accgatcact aaaagtggtg tcaaccatcg tttgcggaaa
     8761 atcaataaga ttgcggatga attgactgac tagataggta tacatagaat gttatggaca
     8821 tttgaattaa ctttgataca tcgttacttt cggcttgccg tactctagta ttgcttacac
     8881 ctcagttcct tgtctgaaag ttaattcatt cgacgatact aagactggtt cgagaggacc
     8941 agttttttgt attagttgtg atagtattcc tcttcacagg aatgatcctg ttttatgaat
     9001 ttttcagtaa tgattagcat agaacgttaa tatatgttaa aatagataga aggatacttt
     9061 agctagaaag gagttttgat gataagcaac gaacaatatg attatctaag ggcacatcca
     9121 acttttgaac gtttgacacg tgatagcttt gatcaattag ctaagcatat tcgttttcga
     9181 aagattccta agggacaaat ctttttttac gcagaggatc ctagagatta tctatttgta
     9241 ttgtataagg gctatgctcg gattgagcaa tatgatgaga cggatagttt tacgtattta
     9301 gactatattc ggcagggtgg tgcctttcct tttggagata tgtttcagga caaaccttat
     9361 cattataccg ccattgccat aacggaccta gagtatttta ttgtaccgat ggtcttgttt
     9421 gaaaccttgt cgaagataaa tccgagtcaa atggcttata tctgtcaaaa attatccaaa
     9481 gtgcttcgtt ttcaagagtt gcgcttgcga aatgcgatgc gttccaaggc atcagatcga
     9541 gtcgttcaag ccttggctct tctttattgg gatatgtgcc agcgagagca gtttgctacc
     9601 ttgccatttg aaattcatat tcaagagatt tcgcgtttag cagctacgac acgggaaacg
     9661 gttagccatg ttttgaagca actgaagcag gatggtaaaa tagcttatag ccataaac
//
LOCUS       DBNFCO010000064         9713 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.064, whole genome shotgun sequence.
ACCESSION   DBNFCO010000064 DBNFCO010000000
VERSION     DBNFCO010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9713)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9713)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9713
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.064"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            53..1333
                     /locus_tag="AC1PIV_001516"
     CDS             53..1333
                     /locus_tag="AC1PIV_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase family
                     protein"
                     /protein_id="HIP6612530.1"
                     /translation="MTREFSFETLQLHAGQEVDSASKSRAVPIYQTTSYVFEDAQEAE
                     DLFALRKSGNIYTRITNPTVSTFENRVAALEGGIGALATSSGMAAITYTILALAHAGD
                     HIVAATTLYGGTFNLFKETLPRYGITTSFVDIDDFEAVEAAIKDNTKLVFIETLGNPV
                     INIPDLEKLAEIAHTYHIPLVSDNTFATPYLINVFSHGVDIAVHSATKFIGGHGTTIG
                     GVIVDSGKFDWAASGKFPQFVEEDPSYHNISYTRDIGVAAFIVAVRVQLLRDTGAALS
                     PFNAFLLLHGLETLSLRVERHVSNAEKIVDFLLNHPNVESVNYPSLPDSPYKALADKY
                     LPKGVGSIFSFQVKGGAEEARKVIDGLEIFSNLANVADAKSLVVHPATTTHAQLAPED
                     LLAAGVTPNQIRLSVGLENINDLIEDLQLALDKL"
     gene            complement(1414..2946)
                     /locus_tag="AC1PIV_001517"
     CDS             complement(1414..2946)
                     /locus_tag="AC1PIV_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HIP6612531.1"
                     /translation="MLLTTHHLSLDHQKDLRNLVQDLNLIVNPGDKIAIIGEEGNGKS
                     SLLLTLMDSTLVADYLLQSGSIHRYFHSPVYIPQSLPLEIAELTLNDYFFADLDSDID
                     YSLLYLYADQLQFDSERFASQQLIESLSGGEKLKIQLIKSLATPSDIIFLDEPSNDLD
                     LDTLLWLENYTITSPKTILFVSHDEDFLSRTATKIIHLESVKKKTLAQTKVEELDYQD
                     YALRRQQAYQKQVQQARNDQKEFDKAMNKHLRQKSQVRHTLLNTHDATLGRLIAKKMK
                     NVLSREKRYERMKENLTQVPFHEDAISLFFSDISPLPARKQVLHLENFQLNVEERQLV
                     SNIHFNINGQEKIGIIGQNGIGKSSFLKLIYQKLRHRADINLGYMPQRYSEVLDESKT
                     PLDFLLENGNREQEQLILTHLASLQFTRQEVHHKICELSGGQKAKLLLLKMVLDQANF
                     LLLDEPSRNFSPTSQPYIRQLFADYPGGLVCVSHDRRFLKEVCQRIYRLTENGLEELG
                     QI"
     gene            3245..3736
                     /locus_tag="AC1PIV_001518"
     CDS             3245..3736
                     /locus_tag="AC1PIV_001518"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIP6612532.1"
                     /translation="MAITGIEQADILEIDKQVRLRRYDGQHDFSFEWHQDLELVWLID
                     GDQERYSLDLLNRMYDYLSKNGECYFIEIFEDNQFIPIGDVTLFADDFAIAIGDKRYW
                     KKGIGTKVLQRMIERAREVGLEEIPVEEIYDWNTGPRKLFEKCGFEAVEKTKKGWSYK
                     MIL"
     gene            complement(3990..4730)
                     /locus_tag="AC1PIV_001519"
     CDS             complement(3990..4730)
                     /locus_tag="AC1PIV_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015424 - ABC-type amino acid transporter
                     activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HIP6612533.1"
                     /translation="MAQLKINVHDLHKSYGKNEVLKGITAKFYEGDVVCIIGPSGSGK
                     STFLRTMNLLETITSGQVTVDGYDLTDPKTDVDAFRSNVGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMDKSEAEKVGMELLEKVGLADKRDAMPDSLSGGQKQRVAIARALAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKDLAEQGMTMLIVTHEMGFARKVANRVIFTDGGEF
                     LEDGTPEQIFDNPQHPRLQDFLDKVLNV"
     gene            complement(4730..6928)
                     /locus_tag="AC1PIV_001520"
     CDS             complement(4730..6928)
                     /locus_tag="AC1PIV_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HIP6612534.1"
                     /translation="MKKKLLMLLASILPVFFIFTGIKADDTIDVVFDNAYAPFEFKDS
                     DQIYKGLDVDIINEVAKRSGWTMNQSFPGFDAAVNAVQAGSADALMAGTTITEARKKV
                     FTFSDPYFDTKIVIATTKANTISSYKDLKGKTVGVKNGTAAQNFLEENKDKYGYNVKT
                     FDTGDLMYNSLSAGAVDAVMDDEAVIQYAIQQGQDLSIDIEGEAIGSFGFSVKKGSQY
                     EYLVEDFNKALAEMKKDGTYEIIMNKWLGASTTSTESTDYSSRLSLTGNASAKATPVK
                     SSYTIVADSSFAPFEYQDESGNYVGIDMELIKAIAEHQGFTITIQNPGFDAALNAVQA
                     GQADAVIAGMSITDARKEIFDFSNAYYTSNILLAVKNGSDIASYEDLKGKTVGAKNGT
                     ASYSFLEENKSKYGYTLKAFDEASSMYDSLNSGSIDALMDDEAVLLYAIQQGRNFATP
                     IPGEKSGEYGFAVKKGANPELIEMFNNGLAALVESGKYDEILNKYFNSTEEASTTTST
                     VDETTIVGLLKNNYGQLLSGLGITIGLALLSFAIAIVIGIIFGMFAVSPVKALRVTSS
                     VFVDVVRGIPLMIVAAFIFWGIPNLIESMTGQQSPINDFVAGTIALSLNSGAYIAEIV
                     RGGIQAVPAGQMEASRSLGISYGTTMRKIILPQAGKIMLPNFINQFVITLKDTTIISA
                     IGLVELFQAGKIIIARNYQSFRMYAILAIIYLVVITLLTRLARKLEKGGK"
     gene            7126..9111
                     /gene="uvrB"
                     /locus_tag="AC1PIV_001521"
     CDS             7126..9111
                     /gene="uvrB"
                     /locus_tag="AC1PIV_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HIP6612535.1"
                     /translation="MINRNTENQFKLVSKYAPSGDQPQAIETLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVIARVNKPTLVIAHNKTLAGQLYSEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYS
                     DSVVSLRPGQEISRDQLLNALVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREIESLTGKVLGDVDHLAIFPATHFVTNDDHMETAIAKIQAELEEQL
                     KVFEAEGKLLEAQRLKQRTDYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PEDYLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYEMEQTETVVEQIIRPTGLLDPEVEVRPTMGQMDDLLGEINARVEKG
                     ERTFITTLTKKMAEDLTDYLKEMGVKVKYMHSDIKTLERTEIIRDLRLGVFDVLIGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADKVTESMR
                     KAMEETARRRQIQMAYNEEHGIIPQTIKKEIRDLISVTKAVTQDKEEVVDFNALNKDE
                     RKAMIKKLEGQMQEAAEVLDFELAAQIRDMVIELKNM"
     gene            9126..9371
                     /locus_tag="AC1PIV_001522"
     CDS             9126..9371
                     /locus_tag="AC1PIV_001522"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612536.1"
                     /translation="MKYFDTSKTTNQVVTCIRQLENTELEKELLQFIEECEKADSLSK
                     EYIERFFKIVDAFLEVFPGSSLDSQHLKKLLTLLHEK"
BASE COUNT         2826 a         1823 c         2166 g         2898 t
ORIGIN      
        1 caagatggta aaaatgaggt agaatacaga aaaagaccaa aggagtacct ttatgactag
       61 agaattttca tttgaaaccc ttcaactcca tgctggacaa gaagttgatt ctgcttcaaa
      121 atcacgtgca gtacccatct atcaaaccac ttcctatgtt tttgaagatg ctcaagaagc
      181 agaagattta tttgcattgc gtaaatcagg gaatatctat actcgtatca ctaatccgac
      241 ggtctctact tttgaaaatc gtgtggcagc tttagaaggt ggtattggtg ccttggccac
      301 ttcttcagga atggcagcca tcacatacac tattctagca ttagcgcatg ctggtgatca
      361 cattgtggcg gcaacgacac tctatggtgg gacttttaac ctattcaaag aaacccttcc
      421 tcgctatggt attacaacaa gctttgtaga tattgatgat tttgaagcgg tagaagctgc
      481 gattaaagat aatacaaaac tggtatttat tgaaaccttg ggaaatcctg ttatcaatat
      541 tcctgatctt gaaaaattgg cagaaattgc acacacctac cacatcccac ttgtttcaga
      601 taataccttc gcaaccccat atttgattaa tgtattttct catggtgttg atattgccgt
      661 ccattcagca accaagttta tcggtgggca tggtacgacc attggcggtg tgattgtcga
      721 tagcggtaag tttgattggg cggcatctgg taagtttccg caatttgttg aagaagatcc
      781 aagctatcat aacattagtt atactcgtga tattggtgta gctgcattta ttgttgcagt
      841 tcgtgtacaa ttacttcgcg atacaggtgc agccctttct ccattcaacg ccttcttgct
      901 tttgcatggg ttagaaacct tgtctctccg tgtagagcgt catgtgtcaa atgctgaaaa
      961 gattgttgat ttcttgctca atcaccctaa tgttgagtcg gtcaattatc catcacttcc
     1021 agatagtcct tataaggctt tggcagataa atacctgcct aaaggtgttg gatctatttt
     1081 ctctttccaa gtaaaaggcg gagcagaaga agcccgaaag gttattgatg gcttggaaat
     1141 cttttctaat ttagcaaacg ttgccgatgc gaaatcacta gtagttcatc cagctacaac
     1201 cacgcatgct cagttagctc cggaagattt acttgctgct ggggtcacac caaatcaaat
     1261 ccgcctatct gttggtcttg aaaatatcaa tgatttgatt gaagatttgc aacttgctct
     1321 tgataaatta taggttgtga atcgaatagc ttggcttcat tctttatgaa taaataataa
     1381 aaggaaattt ggcgtgtgtg ccattttcct tttttatatc tgtcctagtt cttccagtcc
     1441 attctcagtt agtcgataga ttctttgaca aacttctttc aaaaagcgtc tgtcgtgtga
     1501 tacgcatacc aaaccacctg gataatcggc aaatagttga cgaatatatg gctgagaagt
     1561 gggagagaag tttcgactgg gttcatctaa caagagaaaa ttggcttgat caagaaccat
     1621 ttttaacaag agtaacttgg ctttttgtcc ccccgaaagt tcacagatct tgtgatgaac
     1681 ttcttgtcgt gtaaactgca gactggctag atgtgttaag ataagttgct cctgctcacg
     1741 attgccattt tctaataaaa aatcaagtgg agttttagac tcatcaagga cttctgaata
     1801 gcgctggggc atgtatccca agtttatatc tgctcggtgc ctgagtttct gatagattag
     1861 ctttagaaaa ctggatttac caattccatt ttgtccaatg atgccaattt tctcttgtcc
     1921 atttatgttg aaatggatat tgctaactaa ttgtcgttct tcaacgttca attggaagtt
     1981 ttctaagtga agcacttgtt ttctagctgg tagtggtgaa atgtctgaga agaagaggga
     2041 aatggcatct tcatgaaaag gaacttgtgt aagattttcc ttcattcttt catagcgttt
     2101 ttcacgtgag agaacatttt tcattttctt agcaatgagc cgtcctagtg tggcatcatg
     2161 ggtgttgagc aaggtgtgac gaacctgtga tttttgacgt aggtgcttat tcatggcttt
     2221 gtcaaattct ttttggtcgt tccgagcttg ctggacctgc ttctgataag cttgctggcg
     2281 tctcaatgcg taatcctggt aatctagttc ttcaaccttg gtctgtgcaa gtgttttctt
     2341 tttaaccgat tctagatgaa tgatttttgt agctgttctg ctaagaaagt cttcatcgtg
     2401 agaaacaaat aggatggttt taggactagt aatggtatag ttttcaagcc aaagtaaggt
     2461 atctaaatcc aagtcattgg acggctcatc cagaaaaata atatcagatg gagttgctag
     2521 agatttgatt aactgaattt ttagtttttc accacctgac aggctttcaa tcaattgttg
     2581 actggcaaat cgctcactgt caaactggag ctggtcagca tagaggtaga gtaggctgta
     2641 atcaatgtcg ctgtccaagt cagcgaagaa gtagtcgttc agggttagct ctgctatttc
     2701 cagtggaaga ctttggggaa tatagactgg tgagtgaaaa tatcggtgaa tactgcctga
     2761 ttgaagcagg tagtcggcga caagagtgga atccatcaag gtgagtaata gactggattt
     2821 tccgtttcct tcttcgccga tgatagctat tttatcgcca gggttaacaa tgaggtttag
     2881 gtcctgaact agatttcgca aatctttttg atggtcgaga gataggtgat gagtggttag
     2941 tagcataagg cctcctttac aagaaaaaac acactaccta tttagtagtg tgtcgaaatc
     3001 tgctcaaaaa gaccctattc atggaacaga gaaacagaaa aatggacgca agaaaactac
     3061 taaataagta tagaacttaa attgagttta cttgttattg tccatttctc cttacctcgc
     3121 atgctttatt tgttttaata tagcatatcg atagaatctt gtcaatcagc gtgctataat
     3181 attcatagat ttcgatagag atatatgtta aaatgaactt attgtaaatg agagaggatc
     3241 cgaaatggca atcactggaa ttgagcaagc agatatttta gaaatagaca aacaagtccg
     3301 tttacgtcgg tatgatggtc agcatgattt ttcttttgaa tggcaccaag atctagaatt
     3361 ggtctggctg attgatggtg atcaagaacg ttatagtctt gacttgctca atcgtatgta
     3421 tgattatttg tctaaaaatg gcgaatgtta ctttattgaa atttttgaag acaatcagtt
     3481 tatcccaatt ggtgatgtga cgctgtttgc agatgatttt gccattgcca ttggagataa
     3541 gcggtattgg aaaaagggaa ttggaaccaa ggtattacag cgaatgattg aacgtgcaag
     3601 agaagtgggg cttgaggaaa tacctgtaga agaaatatat gactggaata caggcccccg
     3661 taaactgttt gagaaatgtg gctttgaagc tgttgaaaag acaaagaaag gttggtccta
     3721 caagatgata ttgtaaatta attttgagat accaaaaaaa acttgacgaa agtcaaagct
     3781 tcagaacgta gataaactct taaaaatata aaaaattgaa gaagtttgcg aaagatagca
     3841 agtcattaaa ctcttagaaa cattgatatt tcggcgtttc taagagtttt ttattttcaa
     3901 cataaagaaa aaagattgaa gaaaatcgtc caaaatggac tttttcttca atctgaaacc
     3961 ttgatgcaag tcaaggcttt tcgtttagct tagacgttca agaccttatc aaggaagtct
     4021 tgtaaacgtg gatgttgtgg gttatcaaag atttgctctg gtgtaccatc ttcaaggaac
     4081 tcaccgccat cagtgaagat aacgcgatta gcaaccttgc gggcaaagcc catctcgtgt
     4141 gtgacgatta acatggtcat accttgctca gccaagtctt tcataacgtt gagtacatcg
     4201 ccaaccattt cagggtcaag ggcagaagtt ggttcgtcga agagcatgat gtctgggttc
     4261 atagcgaggg cacgagcgat agcaacacgt tgcttctgac cacctgaaag gctgtctggc
     4321 atagcgtcgc gtttgtctgc caatccaact ttttccaata attccatgcc gaccttttca
     4381 gcttcagact tgtccatcaa tttgtgttcg attggcgcaa atgtgatatt gtcaagtaca
     4441 gacatatgag ggaagaggtt gaagtgttgg aataccattc cgacatttga acggaaggcg
     4501 tcaacatctg tcttagggtc ggttaagtca tatccatcga ctgttacttg accacttgta
     4561 atggtttcaa gtaagttcat tgtacgaagg aaggtcgatt tacctgaacc agaaggaccg
     4621 atgatacaaa caacatcgcc ttcatagaac ttagcagtaa tacctttgag gacctcgttt
     4681 ttaccataag acttgtgtaa gtcatggaca ttgattttta attgagccat tatttgcctc
     4741 ctttttcgag tttgcgtgct aagcgagtca agagtgtgat aactaccaag taaatgatgg
     4801 caagaattgc atacatacgg aaggattggt agttacgtgc aataatgatt ttacccgctt
     4861 ggaagagttc gaccaaacca atcgcagaaa tgatagtggt atctttcaga gtaataacaa
     4921 actggttgat aaagttaggc aacataattt taccagcttg aggtaggata atcttacgca
     4981 tggttgttcc gtaggaaata cctaaactgc gagatgcttc catctgacca gctggaactg
     5041 cctgaatacc gccacgaaca atctcggcaa tataggcacc agagttgagg gatagggcga
     5101 tcgtaccagc gacaaagtca ttgattggag attgttgacc agtcatcgac tcgattaagt
     5161 ttggaatacc ccagaagatg aatgcagcga caatcatgag cggaatacca cgaacaacat
     5221 ctacaaaaac agatgaagta acacggagtg ctttaactgg gctgacagca aacataccga
     5281 agataatacc gatcacaatt gcaatagcaa atgatagaag ggcaagtcca attgtgatac
     5341 caagacctga gagtaattga ccgtagttgt ttttcaaaag accaacaatc gttgtctcat
     5401 caacagttga agttgttgtg cttgcttctt cagttgagtt gaaatactta ttaaggattt
     5461 catcatactt gcctgattca actagggcag ctaagccgtt gttaaacatt tcaattaatt
     5521 ctgggttggc acctttttta acggcaaatc cgtactcacc tgatttttcg ccaggaattg
     5581 gtgttgcaaa gttgcgacct tgttggatgg catatagaag aaccgcttcg tcatccataa
     5641 gagcatcaat agaaccagag tttaaactgt catacatact tgaagcttcg tcgaaggctt
     5701 ttagggtgta accatatttt gacttgtttt cttctaagaa actatatgaa gcagtaccat
     5761 ttttagcccc aacagttttc ccttttaagt cctcgtaaga agcgatgtca ctaccatttt
     5821 taacagctaa taggatgttt gaagtatagt aggcgtttga gaagtcaaag atttccttac
     5881 gagcatctgt gatagacata ccggcaataa ctgcatcagc ttgtccagct tgaacagcat
     5941 ttagtgcagc gtcgaaacca gggttttgaa tagtaatggt aaatccttgg tgttcagcga
     6001 ttgccttgat taattccatg tcaatcccga catagttacc tgattcatct tggtattcaa
     6061 atggagcaaa agaagaatct gccacaattg tgtagcttga tttgacaggt gttgctttag
     6121 ctgatgcgtt tcctgttaag cttaaacgag atgagtaatc tgtactttcg gtagaagtgg
     6181 tagaagctcc caaccatttg ttcatgatta tttcgtaggt gccatctttc ttcatctcag
     6241 ctaaagcctt gttaaagtct tcaacaagat attcatattg gctacctttt tttacagaga
     6301 aaccaaatga accgatggct tcgccttcga tgtcaatact taggtcttga ccttgttgga
     6361 tagcgtattg aataactgct tcgtcgtcca ttacagcatc aacagcacca gcagaaaggc
     6421 tattatacat caaatcgcca gtatcaaaag tttttacgtt gtatccgtac ttgtctttgt
     6481 tttcttctag gaagttttgg gctgcagtac cgtttttgac accgacagtc ttgcctttaa
     6541 ggtccttata tgaagagatg gtatttgcct ttgtggtagc gataacgatt ttggtgtcga
     6601 agtaagggtc tgagaaagta aatactttct tacgcgcttc ggtgatagtt gtacctgcca
     6661 ttagggcgtc cgcagatcca gcctgtacag cgttgacagc tgcatcaaat cctgggaagc
     6721 tttgattcat ggtccaacct gagcgcttgg ctacttcgtt gatgatgtca acatctaatc
     6781 ctttataaat ttgatctgag tctttaaact cgaatggggc gtaagcattg tcaaatacga
     6841 catcaatagt atcgtcagct ttaatgccag taaaaataaa gaatactggc agaatgcttg
     6901 ccaataacat gagtaatttt ttcttcattt ccatactcct tctattataa aataactgtc
     6961 ctagtatatc atattctgaa aattaatgca aaattgaggt ttttataatg tcagaatttc
     7021 tgacatacaa agtcattaaa atgtgagaaa atttaatatt ttggacatag ttgtgaatgg
     7081 tttagaatgt ttctccatta gtcgaactta tgataaaata ggagtatgat caatcgaaat
     7141 actgaaaacc aatttaaact tgtgtcaaaa tatgcaccgt ctggtgacca gccccaagcc
     7201 attgaaacct tggttgataa catcgagggg ggcgaaaaag cccagattct catgggggcg
     7261 actggtactg gtaagaccta taccatgagc caggttatcg cccgtgtcaa taagccaacc
     7321 ttggtcatcg cccacaacaa gaccttggct ggtcagcttt atagtgagtt caaggaattc
     7381 tttccagaaa atgcggtcga atacttcgtg tcttactatg attactacca gccagaagct
     7441 tatgtaccgt ctagcgatac ctatatcgaa aaggatagtt cggtcaatga tgagattgac
     7501 aaactccgtc actctgcgac ctcagctctg ctagaacgca atgatgtcat tgtggtagct
     7561 tctgtttctt gtatctacgg tttgggttca cccaaggaat attcagatag cgtggtcagc
     7621 ctgcgaccag gtcaggagat ttcccgtgat cagttgctca atgccttggt ggatatccag
     7681 tttgagcgga acgacatcga cttccaacgg ggacggttcc gtgtgcgtgg cgatgtggtg
     7741 gagattttcc cagcttcccg tgacgaacat gcctttcgtg tggagttttt cggggatgaa
     7801 atcgaccgca ttcgtgagat tgaaagcctg acaggcaagg ttttgggcga tgtggaccac
     7861 ttggccattt tccctgccac ccacttcgtg accaacgatg accacatgga aacggccatt
     7921 gccaagattc aggcggaact agaagagcaa ctcaaggtct ttgaggcaga aggaaaactc
     7981 ttagaagctc agcgattgaa acaacgaacc gactacgata tcgagatgct tcgggagatg
     8041 ggctatacca acggagttga gaactattca cgacacatgg acgggcgaag tgagggggag
     8101 cctccttata ccctgctgga ctttttccct gaggactatc tgattatgat tgacgagagc
     8161 cacatgacca tggggcagat taaggggatg tacaatggtg accgctcacg caaggagatg
     8221 ctggttaact atggtttccg tctaccgagt gcattggata atcgtccgct gcgcagggaa
     8281 gaatttgaga gtcatgtcca ccagattgtc tatgtatctg cgacgccggg tgactatgaa
     8341 atggagcaga cagagaccgt tgtcgagcag attatccggc cgaccgggct tttggatcca
     8401 gaagtggaag tccgtccaac tatgggccaa atggacgacc tcctaggtga aatcaatgcc
     8461 cgtgttgaaa aaggcgagcg aacctttatc actaccctga ccaagaaaat ggcagaggac
     8521 ttgaccgact acctgaaaga aatgggcgtc aaggtcaagt atatgcactc ggacatcaag
     8581 accttggagc gtacggagat tatccgtgat cttcgcttgg gtgtctttga tgttttgata
     8641 gggattaacc tgcttcgtga agggattgac gtgccagaag ttagtctagt cgctatctta
     8701 gacgcagaca aggagggctt cctccgtaat gaacgggggc tcatccagac aatcggtcga
     8761 gcggctcgta actctgaagg tcatgtgatt atgtatgcgg acaaggtcac cgagtccatg
     8821 cggaaggcca tggaagaaac agcccgccgc cgtcaaatcc agatggctta taatgaagag
     8881 catggcatta ttccacagac cattaagaaa gagatccgtg acctgattag cgtgaccaag
     8941 gctgtcactc aggacaagga agaggttgtg gacttcaatg ctcttaataa agatgaacgc
     9001 aaggccatga tcaagaaact ggaaggtcag atgcaggaag ccgcagaagt gcttgacttt
     9061 gaactggcag cccagattcg cgatatggtc attgagttga agaatatgta gatatggagg
     9121 tagttatgaa atattttgat acgtcgaaaa caactaatca agtggtaacc tgtattagac
     9181 aattggaaaa tacagagcta gaaaaagagt tgttacagtt tattgaagag tgtgagaaag
     9241 cagactctct atccaaagag tatatagaac gtttttttaa aattgtcgat gcttttcttg
     9301 aggtgtttcc aggatcatcc ttggattcgc agcacttaaa gaaactcttg actttgctcc
     9361 atgaaaaata aaaacagaag aggtgtgggc ggaaatcttt tatagagata cctctaacat
     9421 tagtgcttat tctagattat ttagggaatt aattgttcga gttagcactt atgatcaaat
     9481 tagagatttt gttgataggg gaagtatttt tgggacgcta ttggaaagta gagaaagtgt
     9541 gagtcatact gtaaccagac tcaatttact aatactgata tatttcgtat ttaccttttt
     9601 gtttatttct gatacggata aagaaaagtt taaattacag atagattcct atattcagga
     9661 attacttcaa tgtgataagt atttagacca aatggcctta ttttatttgc tat
//
LOCUS       DBNFCO010000065         9340 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.065, whole genome shotgun sequence.
ACCESSION   DBNFCO010000065 DBNFCO010000000
VERSION     DBNFCO010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9340)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9340)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9340
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.065"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(<1..407)
                     /locus_tag="AC1PIV_001523"
     CDS             complement(<1..407)
                     /locus_tag="AC1PIV_001523"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase"
                     /protein_id="HIP6612537.1"
                     /translation="MKKIVFVCLGNICRSPMAEFVMKDMTSQFHIESRATSNWEHGNP
                     IYPGTQKIFQKHKISYDQDKSSQQMSQTDFEAFDIIIGMDSNNVRDLQKIAPAHAQNK
                     IFQFAEKSVPDPWYTGDFDETYEMVKKGCQDWL"
     gene            complement(577..789)
                     /locus_tag="AC1PIV_001524"
     CDS             complement(577..789)
                     /locus_tag="AC1PIV_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HIP6612538.1"
                     /translation="MSEEKFDAKLEQLSGSAKEVIGKLTGDKEIEVEGLVEKGIGKAK
                     ELVEDAKDGLEGAINGIKNAFDKEEK"
     gene            991..1509
                     /locus_tag="AC1PIV_001525"
     CDS             991..1509
                     /locus_tag="AC1PIV_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Dps family protein"
                     /protein_id="HIP6612539.1"
                     /translation="MMKQKYYQSPAEIASFSPRPSLADSKAVLNQAVADLSVAHSILH
                     QVHWYMRGRGFMIWHPKMDEYMEEIDGYLDEMSERLITLGGAPFSTLKEFSENSQLKE
                     VLGDYNVTIEEQLARVVEVFRYLAALFQKGFDVSDEEGDSVTNDIFNVAKASIEKHIW
                     MLQAELGQAPKL"
     gene            1870..2748
                     /locus_tag="AC1PIV_001526"
     CDS             1870..2748
                     /locus_tag="AC1PIV_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIP6612540.1"
                     /translation="MIEVQALEKIIKGRTILSTISFEIKSGECVALIGPNGAGKTTLM
                     SCLLGDRKATKGQVLLDGLAPQARSNKETVAVLPQENAIPTDLKVKELLRFFQAIYKD
                     SLTDVEIDSLLCFSQEQKNQLAGKLSGGQKRLLAFVICLIGKPKLLFLDEPTAGMDTS
                     TRQRFWEIVHELKAQGVTIFYTSHYIEEVEHTAERILVLHQGRLLRDTTPFAMRSEEQ
                     EKEVTLPIAFAAVVESLAEINGISYKQDTVSFKTRAIEQVWASLQEAGCRISDLEVQN
                     KTLLNSLFDKTREEES"
     gene            2745..3476
                     /locus_tag="AC1PIV_001527"
     CDS             2745..3476
                     /locus_tag="AC1PIV_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIP6612541.1"
                     /translation="MKALVQVEAVKLSRSLGVFLLSIGMPVIFFLIFSSTVRFDDAAM
                     QKAFIQSYMLTMTGFSMSGFALFTFPMMLAEDRKNSWLTFIQHSPLPIWHYYLSKLVR
                     VLLCFVSSIAVVFAVGGLVKGVDLSAQEWVVSALILLVTSIVFLAIGLLLVQIQSEQA
                     MSVVANLLYFVLAIMGGSWMPVSLFPDWVQRICKLMPSYHVNQLVTTYAQEGDFLWKS
                     LLIVLGYAIIFLGIALVLNRKSEQQ"
     gene            3485..4579
                     /locus_tag="AC1PIV_001528"
     CDS             3485..4579
                     /locus_tag="AC1PIV_001528"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIP6612542.1"
                     /translation="MIFEKRKVPLMFFVGMVFLYFPFYYAQYSPNPTAVVLATILFAL
                     VYCSLFYTDHKLYSLLAWFYLIGYIAVMSFWGNLQFSLFIFNLSNMLGWYYKETRPTY
                     RTVSSGILLLAIILWALFGPVPFEMRAFALVIHFFGLALLIFSWIEIKREALQQRLQE
                     QNASINLLLAENERNRIGQDLHDTLGHVFAMLSVKAELVQTLLDHDQIDQAKKEVQEL
                     QTLAKDSMQDVRQIVQSLKQYTVAEELQILQQMLDLAGVDLLVLGGEIAEHLSLPVQN
                     KLAMVLRELGNNLLKHSQASRCRLVFEKDQQELVLYYEDNGVGFAKLTGQELHTIKDR
                     LVTVKGSLEFLSLANPTRLSIRIPFEEVVE"
     gene            4576..5178
                     /locus_tag="AC1PIV_001529"
     CDS             4576..5178
                     /locus_tag="AC1PIV_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HIP6612543.1"
                     /translation="MRILVAEDQAMLRDALCQLLCFQDAVEAVLQAENGSQAIALLEK
                     EPVDVVLLDIEMPEKTGLDVLEWVRGQALPVKVVIMTTFKRPGYFERAVKADVDAYVL
                     KERSIADLMRTIETVLAGRKEYSPELMDILLTQRSPLTNLESQLLKLVAEGLSNKEIA
                     CQLHLSDGTVRNYMTSILSKLGAENRTAAVKVAQEKGWLV"
     gene            5486..5704
                     /locus_tag="AC1PIV_001530"
     CDS             5486..5704
                     /locus_tag="AC1PIV_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HIP6612544.1"
                     /translation="MKRLYDVQQLLKRFGIIVYMGNRLYDIEMMQIELNRIYQAGVLD
                     RLEYMEAELVLRREHRLELEYQKSRENE"
     gene            5704..6090
                     /locus_tag="AC1PIV_001531"
     CDS             5704..6090
                     /locus_tag="AC1PIV_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HIP6612545.1"
                     /translation="METFWVFLVFLAVLGAWMGFNYWRLRRAATVIDNAEFAEKIHGG
                     QLIDLRDPSEFNRKHILGARNIPYQQLRQSTAALRKDRPVLIYENDRGQLVTPAALHL
                     KKQGFNEIYILSYGLNGWNGKVKTTK"
     gene            6147..6869
                     /locus_tag="AC1PIV_001532"
     CDS             6147..6869
                     /locus_tag="AC1PIV_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HIP6612546.1"
                     /translation="MEKKFEKLSLAEIGIISFMGLILLISLGASWYKNAQSETSDTKT
                     VQQVSNQKKTVDTLFQDAENAVIVLEGTHTEEKLAEAQSAVNKVTDATKKAALQKRID
                     QVKELVGQQTDAQTQAKLKAELVRAEAAQKVADEKKVSETGTSQSTDLAEASETSQES
                     YVVPNQNIYGNQSVSSTSQYTSSVASTSTSTSVPPTSEGAPVVETPTVSEAPAETTDS
                     TTSLVESVETVPTADESSPDNP"
     gene            7177..7716
                     /gene="rsmD"
                     /locus_tag="AC1PIV_001533"
     CDS             7177..7716
                     /gene="rsmD"
                     /locus_tag="AC1PIV_001533"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HIP6612547.1"
                     /translation="MRIVSGSYGGRPLKTLDGKTTRPTSDKVRGAMFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAISRGMESAVLVERDRRAQAIIRENIAMTKEADKFQLLAMEARQ
                     ALNSVGGPFDLVFLDPPYAEQEIEDVITELCRRDLLADDVMVVCETDKAVSLPEEIAE
                     LGIWKEKLYGISKVTVYVR"
     gene            7706..8194
                     /gene="coaD"
                     /locus_tag="AC1PIV_001534"
     CDS             7706..8194
                     /gene="coaD"
                     /locus_tag="AC1PIV_001534"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HIP6612548.1"
                     /translation="MSDKIGLFTGSFDPITNGHLDLIERASGLFDKLYVGVFTNPKKA
                     GLLTGLERKAILEKLFVGMENIEVVLSENELVVDVAKRYGVTHLVRGLRNATDLEYES
                     SFDFYNRQLAPGLETIYLIAKPELKFVSSSQVRELLYFKQDIGPYVPEIVSEEIRKNE
                     EK"
     gene            8181..9230
                     /locus_tag="AC1PIV_001535"
     CDS             8181..9230
                     /locus_tag="AC1PIV_001535"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SepM family pheromone-processing serine
                     protease"
                     /protein_id="HIP6612549.1"
                     /translation="MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQV
                     LTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDPYTTVRSSEEMTGGADNEEYFRI
                     ARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
                     TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEV
                     QSSIPIDFQTGDIGGPSAGLMFTLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGG
                     ADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEAAEKAGLDIEVVPVK
                     TVQEAIDYLKKTKGE"
BASE COUNT         2605 a         1786 c         2218 g         2731 t
ORIGIN      
        1 tccaaccagt cttgacaacc tttctttacc atttcgtagg tttcgtcaaa atctccagta
       61 taccaagggt ctggtacgga tttttctgcg aattgaaaaa tcttattttg ggcatgtgct
      121 ggtgctattt tctgtaaatc tcggacatta ttgctgtcca taccgatgat aatatcaaat
      181 gcttcgaaat ctgtctggct catttgctgt gatgatttat cttggtcata ggaaatcttg
      241 tgcttttgga aaattttctg tgttccaggg tagataggat taccatgttc ccagtttgaa
      301 gtagcacggc tttcaatgtg aaattgactt gtcatgtctt tcatgacaaa ttcagccata
      361 gggctacgac aaatatttcc aagacagaca aaaacgattt ttttcataga tactcctttc
      421 gtgacataag aaaagagaag gtagactcga caggtaaatg tctgagttcc cctctcttgc
      481 atatttttgt tcgggctata ggtaaaagac caaattaagt gtaatgttca ttatcaaaca
      541 gtgcacgacc aatcctacct atattgaact ctttgtttat ttctcttctt tgtcgaaagc
      601 atttttgatg ccgttaatgg caccttcaag cccatctttt gcatcttcga ctagctcttt
      661 tgctttgcca attcctttct caacaagtcc ttcaacttcg atttccttgt cgccggtcag
      721 cttaccaatt acctcttttg cagatccaga tagctgttct agttttgcgt caaatttttc
      781 ttctgacata aaatccctcc tcgatataca catatggggg cgatgatttt ctaaaaagaa
      841 aatcacatac tattcttact tactagtcta acgtatataa gttaatatag caaggaattt
      901 gtctgccaat aattcagagg aggagggata attcttgcaa ttttttcttc ttttatttat
      961 aattattata aataaaagaa agggtgatat atgatgaaac aaaaatatta tcaatctcca
     1021 gcagaaattg cgtctttcag cccgcgtcca tcactggctg attctaaggc tgttttgaat
     1081 caagcggtgg ccgatttatc agtagcccat tcaatcctcc atcaagttca ctggtatatg
     1141 cgtggtcgtg gctttatgat ttggcatcca aagatggatg aatatatgga agaaattgat
     1201 ggttatttgg atgagatgag tgagcgttta atcaccttag gtggggcacc attttctacc
     1261 cttaaagagt ttagtgaaaa tagtcagctc aaggaagttc ttggtgatta caatgtaacg
     1321 attgaagagc aattggcgcg tgtggtagag gtgttccgct atctggctgc tcttttccaa
     1381 aaggggtttg atgtcagtga tgaagaaggt gacagcgtaa ccaacgacat tttcaatgtg
     1441 gctaaggcta gtattgaaaa acatatttgg atgctgcagg cagaacttgg tcaagcacct
     1501 aagttgtaaa tagatgaagg gtccacagta ggactctttt tttgctacat tatttaatac
     1561 tcttcgaata tcaaaattat ccgttgtcaa cttgccttga tgaactccag atctatcttc
     1621 gacttcgttt cctaggctac ttttgatttt cattgagtat aatatgacat ttgtcacatg
     1681 agtccatgac aaaggcttct agtggggtct cctttttcga gatatactgt ctatgtatcg
     1741 tcatttagtt tttcttttat tacttcgtta actcgccttg cctaattcca gttatgcctg
     1801 cggctcgttg cctagtacta aaagtaaact aaaagactat aagatgttca agaagtagga
     1861 ggtagaaaaa tgatagaagt acaagcacta gaaaaaatca tcaaaggacg gacgattttg
     1921 tccactattt cctttgaaat caagtcagga gaatgtgtgg ctttaatcgg tccaaacggg
     1981 gctggaaaaa cgacgcttat gtcttgtttg ttgggtgata gaaaggcgac gaaaggccag
     2041 gttttgttgg acggtctggc tccacaggct cggtccaata aagaaacggt agcagtctta
     2101 ccacaagaaa atgctatccc gacagacctg aaggtcaagg aattactccg ctttttccaa
     2161 gctatttaca aggatagtct gacagatgtg gaaatcgaca gcctgctctg cttttcccaa
     2221 gagcaaaaaa atcaactggc cggcaagcta tcgggtggtc agaagcggct cttggctttc
     2281 gtcatctgcc taattggcaa gcccaagttg ctcttcttgg acgagccgac ggcgggcatg
     2341 gatacttcga cccgccagcg tttttgggag attgtccatg aacttaaggc tcagggtgtg
     2401 actatttttt ataccagcca ctatattgag gaagtggagc atacggcgga gcggattttg
     2461 gtcttgcatc aggggcggct actaagagat accacgccat ttgctatgcg gagtgaggag
     2521 caagaaaaag aagtgacttt gccgattgcc tttgcggcgg tggtggagag cttggctgaa
     2581 atcaatggga tcagctacaa acaagatacg gtcagcttca agacccgagc tattgagcag
     2641 gtttgggcta gtttgcagga ggcaggttgt cggatttcag acctggaagt gcagaataaa
     2701 actctgctca atagcctatt tgacaagacg agggaggaag aatcatgaaa gcattagttc
     2761 aagtagaggc ggtaaaatta tccagaagtt tgggagtatt tctcctgtct atcggtatgc
     2821 ccgtcatctt tttcctgatt ttctcatcaa cggtccggtt tgatgatgca gccatgcaaa
     2881 aggcctttat ccagtcctac atgctgacaa tgacaggttt ttccatgtcg ggctttgccc
     2941 ttttcacctt tcccatgatg ttggcagagg acagaaagaa tagctggttg acctttatcc
     3001 agcattcacc cctgccaatc tggcactact acctatccaa actggtacgg gtcttgctct
     3061 gctttgtatc ttccattgcc gttgtctttg cggtgggtgg cttggtcaag ggagtagatt
     3121 tgtcagctca ggaatgggtc gtgtccgcac tcatactcct tgtaacttct atcgtatttc
     3181 tagctatcgg cttgctcttg gtgcaaatcc agtctgaaca ggccatgtcg gttgtggcaa
     3241 acttgctcta ctttgttctg gctatcatgg gtggctcttg gatgcctgtt tccctctttc
     3301 cagactgggt gcagcggatt tgtaaactta tgcctagcta ccatgtcaac cagctggtga
     3361 ccacctatgc ccaagaggga gattttctct ggaaatcctt gctaattgtc ctaggctatg
     3421 cgataatttt cttaggaatt gctctagttc tgaatagaaa atccgagcaa cagtgaggta
     3481 agccgtgatt tttgaaaaaa gaaaggtgcc gctcatgttc ttcgtgggca tggtctttct
     3541 ctattttccc ttttactatg cccagtatag tcccaatcca acagcagttg tcctagcgac
     3601 tattctcttt gccttggttt attgctccct cttttatacc gaccacaagc tctattccct
     3661 gctggcttgg ttttacctga ttggctatat cgccgtcatg agtttttggg gcaatctgca
     3721 attttccctc ttcatcttta acctgtccaa tatgctaggc tggtactaca aggaaactcg
     3781 gccgacctat cggacggtgt cctctgggat cttgttactg gccattatcc tctgggctct
     3841 ctttggccct gttccttttg agatgagagc ttttgcactt gttatccact tctttggctt
     3901 ggccttgctg attttcagct ggattgagat caagcgggaa gcccttcagc aacgcctaca
     3961 ggagcagaat gcgtccatca atctcctgct ggctgagaat gaacgcaacc gtatcggtca
     4021 ggacttgcac gatacgctgg ggcatgtctt tgccatgctg tctgtcaagg ctgagctggt
     4081 ccagacactt ttagaccatg atcagattga ccaggccaag aaggaagtgc aggagctcca
     4141 gaccttagcc aaagactcca tgcaggatgt tcgccagatt gtccagtccc tcaagcagta
     4201 caccgtggca gaggaactcc agattttaca gcagatgttg gacctggcag gagtggattt
     4261 gcttgtcttg ggcggggaaa tagcagagca tctcagctta cctgtccaga acaagctggc
     4321 tatggtgctg agagagttgg gcaataacct gctcaagcac agtcaggcta gcagatgccg
     4381 gttggttttt gaaaaagacc agcaagaatt ggttttatac tacgaagaca atggtgtggg
     4441 ctttgccaag ttgactggtc aggaattaca taccataaaa gacaggttgg tgacggtgaa
     4501 aggcagtttg gagtttcttt ctctggcaaa tcccacccgc ctgtccatcc gaattccgtt
     4561 tgaggaggtg gtagaatgag aatcttagtc gcagaagacc aagcaatgct gcgggacgcc
     4621 ctctgtcagc tcttgtgttt tcaagatgcg gttgaggctg ttttacaggc agaaaacggc
     4681 agccaggcca ttgctctttt ggaaaaagag ccagtagatg tggtgttatt agatatagaa
     4741 atgcctgaaa agacgggcct agatgtcttg gaatgggtgc ggggtcaagc cttgcctgtc
     4801 aaggttgtca tcatgaccac cttcaagcga ccgggctatt tcgagcgagc ggtcaaggca
     4861 gatgtggatg cctatgtgct caaggaacgc tccatcgcag acctcatgcg gaccattgag
     4921 acggtcttgg cagggcggaa ggagtattcg ccagagttga tggatattct cttaacccaa
     4981 cgcagccctt tgaccaacct agaaagtcaa ctactcaagc tggtggcaga ggggctgtcc
     5041 aataaggaaa ttgcctgcca gctccacctg tctgacggga cagtccgcaa ctacatgacc
     5101 tctatcctgt ccaagctagg cgccgaaaac cgcaccgccg ctgttaaggt ggcacaggaa
     5161 aagggttggt tagtataaac gaatgagatt gggcatttgt ccaatctttt tatagaccgg
     5221 atttttgact gagtttttat actcttcgaa aatcaaaatc agacgttgtt gacttgattt
     5281 gatgagtaaa aggctccagt ggagcctttc agcctgttcc cttgaaacaa aatagtaaca
     5341 gggttctatc tgcgtaagta gtaacgaact acgttcgctc tatctccaac ctctaaaggt
     5401 tccccaaacc tttggagcta gtctgttttt gattttcatt gagtattata ttgaaaaaca
     5461 cctaaaattc tgctacaatt tttttatgaa aagactttat gatgtgcaac aattactcaa
     5521 acggtttggt ataattgtct atatgggcaa ccgtctctac gatattgaaa tgatgcagat
     5581 agaattaaat agaatctatc aggcaggtgt cttagatcgg ttggaatata tggaagcaga
     5641 gcttgttttg aggcgtgaac atcgtttgga attagagtat cagaaatcaa gggagaatga
     5701 gtgatggaaa cattttgggt atttttagta tttttggcag tattgggagc ctggatgggc
     5761 tttaattact ggagattgcg tcgtgcagcg actgtgattg ataatgcaga atttgcagaa
     5821 aagatacacg gaggtcagtt gattgacctg cgagacccga gtgagtttaa tcgtaagcat
     5881 atcttaggtg cgagaaatat tccttaccag caattgcgcc agtctacagc tgctttgcgt
     5941 aaggacagac ctgtcttaat ctatgagaat gatcgtggtc agttggtaac gcctgcagcc
     6001 cttcatctga agaaacaggg ctttaacgaa atctatattt taagctatgg tctaaacgga
     6061 tggaatggta aggtaaaaac aactaagtag cattgtcagt aggctagagt attttcttat
     6121 gcaataagac ggataaggga aaaaatatgg aaaagaaatt tgaaaagttg tcattggcag
     6181 aaattggcat tatttctttt atgggactta ttttattgat tagcttaggc gctagttggt
     6241 ataaaaatgc tcaaagcgaa acaagtgata caaagacagt acagcaagtg tccaatcaga
     6301 aaaaaacggt tgatacatta tttcaggatg ctgagaatgc tgtcattgta ttagaaggaa
     6361 cacatactga agagaaactt gcagaggcac aatctgcagt aaacaaggtt acggatgcga
     6421 ctaaaaaagc agcattacag aaacggattg accaagtaaa agagctagtg ggacagcaga
     6481 cagatgctca aacacaggct aagctaaaag cggagttggt cagagcggaa gcagcccaaa
     6541 aagtagctga tgagaaaaaa gtatctgaaa cagggactag tcagtcaacg gaccttgctg
     6601 aagctagtga gacctcacaa gaatcctatg tagtgcctaa tcaaaatata tatggaaatc
     6661 aaagtgtgag ttcaacaagc cagtatacaa gcagcgtggc gtcaactagt acaagtactt
     6721 cagtgcctcc gactagtgaa ggagcacctg tggtagaaac tccaacagtt tctgaagccc
     6781 cggcggaaac gacggattca acaactagcc tggttgagtc agtagaaaca gttccaacag
     6841 ctgacgagag ttcaccagat aatccgtaga ctttttagct actggttctt tatggcgtat
     6901 tagcatactg gaaaaaatag ctatttgtat ttcaacatca attttttctt gtaacgatct
     6961 agtttaaata catacgataa gagtgaggaa tttcgcgtaa aacagaattt ccttgctttt
     7021 tatttttatc attttgttga atagtgcgag aataatttcc tgctatagcg gttgagagtg
     7081 tatttggtag aaggttgaaa aagttggtgc aaaaaggaaa gcaggaagtg cacttggttt
     7141 cagcaacgag cttcattttt tgctataata taccttatga gaattgtatc gggaagctat
     7201 ggtggaagac cactgaaaac gttagatgga aaaacaacca gaccgacatc ggataaggtc
     7261 cgtggagcca tgttcaatat gattggtccc tattttgagg gtggtagagt tcttgacttg
     7321 tacgccggca gtggtggttt atctatcgag gctatatctc gtggcatgga gtcagcagtt
     7381 ctggttgagc gagatcgacg agcacaagcc attatccgtg aaaatattgc aatgactaag
     7441 gaagcagata aatttcagct tctagcaatg gaagctagac aggctttgaa cagtgtggga
     7501 ggtcctttcg acctggtatt cttggaccct ccttatgcag agcaggaaat tgaagatgtg
     7561 ataacagaac tttgtcggcg tgacttacta gcagatgatg ttatggtagt ctgcgaaacg
     7621 gataaggcgg tctctcttcc ggaggaaata gcagagctgg ggatatggaa agagaaactc
     7681 tacggaatta gtaaggtaac agtatatgtc agataagatt ggattgttta cgggctcatt
     7741 tgaccccatt accaatggac acttggactt aattgaacga gcgagtggac tatttgataa
     7801 attatatgtg ggagttttta ccaatcctaa aaaggcagga ctcttgacag gtttggagag
     7861 aaaagccatt ttggagaagc tttttgtagg aatggagaat atcgaggtcg ttctgtctga
     7921 aaatgaattg gtagtcgatg tagctaagcg ctatggagta acacatttgg tccgaggatt
     7981 gcgtaatgcg accgatttgg aatacgagtc aagttttgat ttttacaatc gtcagttggc
     8041 gccaggtttg gaaactattt atttaatcgc caagccagag cttaagttcg tatcatccag
     8101 ccaggttaga gaattgctgt atttcaaaca ggatataggc ccttatgttc cagaaattgt
     8161 tagtgaggag attagaaaga atgaagaaaa ataggaagtt aaccttaatt gcatctattg
     8221 ttttaggaac tcttttgatt tggtttgccg tttttgttcg tctgccttat tatctggaaa
     8281 gtccaggtgg agctgccgat attcgtcagg tactaacggt gaacaatcaa atagaccaag
     8341 aggatggctc ttacaacttc acctatgtat cagtccaaca ggctacagct ttacaactat
     8401 tcgctgctca gtttgatccc tatacgacag ttcgttcctc tgaagagatg acaggagggg
     8461 ccgacaatga ggagtatttc cgtatagcac ggttttacat ggagacatcg caaaatatgg
     8521 cgaagtacca aggtttgacc ttggcaggaa aagaagtcaa tcttgatttc tttggtgtct
     8581 atgtgcttgc cttgacggat gattcaacct ttaaaaaagt tcttaatatt gccgacactg
     8641 ttgtgagtat caatggaaaa acatttgagt cttctcctga tttgattaaa tatgtgagtg
     8701 gcttggaggt tggaagtgat gtaacagttg gttatattag cgctggtcag gaaaaatctg
     8761 cggacggtaa gattatcaaa ttgtctaatg gcaaaaacgg gataggtatc actctcgtag
     8821 atcatacaga ggttcaaagt tcgattccga ttgatttcca aacaggagat attggtggtc
     8881 caagtgctgg tctgatgttt acacttgcca tctatactca actcgcagag cctgacttac
     8941 gtgatggtcg gattattgct ggtacgggga ctatcgagca ggatggaaaa gtaggtgaca
     9001 ttggtggggc tgataagaag gtcatttcgg cagctaagtc tggtgcaagt atcttttttg
     9061 taccaaacaa tccagttgat gtagaagttt tgaagaaaaa tccaaaggct aaaacgaact
     9121 atgaagaagc taaggaagca gccgagaaag caggtctaga tattgaggta gttcctgtga
     9181 aaactgttca agaggctatt gattatttga agaaaacaaa gggcgagtaa atcgtccttt
     9241 tttgctagag aataatatta taattgtcag aaatttctcc taaatggtaa agtagaagaa
     9301 tttccagata aatcgtgtta taatgataag gttaagtgtg
//
LOCUS       DBNFCO010000066         9282 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.066, whole genome shotgun sequence.
ACCESSION   DBNFCO010000066 DBNFCO010000000
VERSION     DBNFCO010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9282
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.066"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            <1..1164
                     /locus_tag="AC1PIV_001536"
     CDS             <1..1164
                     /locus_tag="AC1PIV_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HIP6612550.1"
                     /translation="KKQSPFIIAGIVMLGVVMRAPFTALPAILIDVAAGLRVEVSSLG
                     ILTSIPLIMFALCSSLAPRLAAKFGMEKLMALVLLVMVLGSGMRVLNLPALYIGTMLV
                     GATIAFINVLLPSLVAANFPKKIGLYTTIYITLMGVAATVASMIAVPIVSSSSWEFFI
                     LLITGLVFMAFLIWLPNVKNNHRFASENQGNQKSSIWKNKAAIAFLIFGGLQSVLYYT
                     EITWLPTISQSVGFSKAEAGLMAGFFNMTAIPMSMIIPAVLSRQTKEMRRNIMLAISS
                     VTLLGLFMMSLIPTNLILWSALHIILSFSNAALFPYMMLSFTLKTSNSQATAQLSGMV
                     QTGGYLIAAFGPGLLGYSYPIFGNWMPLILALAIVTLAMMWTIVLIEREDIIL"
     gene            complement(1264..1434)
                     /locus_tag="AC1PIV_001537"
     CDS             complement(1264..1434)
                     /locus_tag="AC1PIV_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003002781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HIP6612551.1"
                     /translation="MAKGFGKGFLTGVLSTVALAAGAVFTVHKTIIEPEEKKEAFIEE
                     NRKKAARKRVAH"
     gene            1503..2387
                     /gene="miaA"
                     /locus_tag="AC1PIV_001538"
     CDS             1503..2387
                     /gene="miaA"
                     /locus_tag="AC1PIV_001538"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HIP6612552.1"
                     /translation="MKTKVIVVIGPTAVGKTALGIDLAQRYNGEIISGDSQQVYRKLD
                     IGTAKASPEEQAAAVHHLIDVRDVTEGYSAYEFVAEAKALIADIKSRGKLPIIVGGTG
                     LYIQSLLEGYHLGGLVDQEQVLAYRAELDCLSDEDLETMAEQAGLMVEGNSRRRIIRG
                     LELKKFGENLENTESGYEPLYICLTDDRQVLYDRINQRVDKMMAAGLLDEVSWLYQEH
                     PEAQAAMGIGYKEFFPYLEGQISLEEAIDNVKQNSRRFAKRQLTWFRNRMAVDFYQVS
                     EEAVKDRIYTAVEEFLDD"
     gene            2380..3630
                     /gene="hflX"
                     /locus_tag="AC1PIV_001539"
     CDS             2380..3630
                     /gene="hflX"
                     /locus_tag="AC1PIV_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HIP6612553.1"
                     /translation="MIETQKEQERALLVGVELQQTDNFDVSMEELASLAKTAGALVKG
                     VYTQKREKYDSKTFVGSGKLDEIAQMVEADEIDTVIVNNRLTPRQNVNLEEILGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYMLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSIRNQIHDIERQLKTVEKNRATVRERRLQSGVFKIGLIGYTNAGKSTIMNAM
                     TDKRQYEADELFATLDATTKQINLADKFNVTLTDTVGFIQDLPTELISAFKSTLEESM
                     NVDLLLHIIDASDPNHSEQEQVVLDILKDLDMLDIPRLALYNKLDKTDDSFTPSQFPH
                     VMLSTKDENAKGHIQMMVLAKIKTMFERFEVRVPLAESYKLHDLATLALIENRTYEED
                     VEVVSGYIASSNKWKLEEFYDGLS"
     gene            3614..4243
                     /locus_tag="AC1PIV_001540"
     CDS             3614..4243
                     /locus_tag="AC1PIV_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HIP6612554.1"
                     /translation="MTDYLDLAIKYGGFTSLDKVYLARKLADMTDQQKLDFITPPPSV
                     INAYFAEIYQKQGAEEATDYYLTLSQQLCLFPKEPSFAESKPFVRLNLSGKSFGFTYV
                     SADGLAQVFSEVGEEVTDSLLFEIAQVFPHYVVFVEEGKIFMKVNPFEDAELEEVETD
                     YLLTQVATGEGLVKISGFNQEEVLEVADGYAGQHYYVWSGRSAILYIKH"
     gene            4254..5183
                     /gene="rnz"
                     /locus_tag="AC1PIV_001541"
     CDS             4254..5183
                     /gene="rnz"
                     /locus_tag="AC1PIV_001541"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016891 - RNA endonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA];
                     GO_process: GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HIP6612555.1"
                     /translation="MQIQFLGTGAGQPSKARNVSSLALKLLDEINQVWLFDCGEGTQN
                     RILETTIRPRKVAKIFITHLHGDHIFGLPGFLSSRSFQSSEEQTDIDIYGPVGIRSFV
                     LASLKVSGTRLPYRIHFHEFDVDTVGQVLETDKFTVFAEKLDHTIPCVGYRVIQKDLE
                     GTLDAEALRAAGVPFGPLFGKIKNGQNVTLEDGTEIIASDYISPPRPGKVVTILGDTR
                     KCHASVRLAVNADVLVHEATYGKGDEKIARKHGHSTNMEAAQVAKDAGVKQLLLNHIS
                     PRFLSKDISQLRKDASTIFEQVHIVKDLEEIEL"
     gene            5180..5935
                     /locus_tag="AC1PIV_001542"
     CDS             5180..5935
                     /locus_tag="AC1PIV_001542"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0070401 - NADP+ binding [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HIP6612556.1"
                     /translation="MRTILITGASGGLVQEMVPLLKDDFLILLGRDVAKIEQLYAYHE
                     KKAVFDVDIRDEIALTAFFDELDSQFGQIDILVNNAGYAIYDDFENFSSQQVQAMFDI
                     NTFALMTMCRLVGKRMKARRSGQIINIISMSGLIASAKSSVYSATKFAAMGFSNTIRL
                     ELAQYGVTVTTVNPGPIATSFFDQADPDGSYQESVKAFLLQPDYVAKKIVSAMGTKKR
                     DINLPWSLAAAHKLYTLFPRIADYLASTVFNLK"
     gene            complement(5979..9164)
                     /locus_tag="AC1PIV_001543"
     CDS             complement(5979..9164)
                     /locus_tag="AC1PIV_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M14 family zinc carboxypeptidase"
                     /protein_id="HIP6612557.1"
                     /translation="MKLSYKKRLLNQVLLASTVLLAASLAQGTVFANTEEIPPTTSET
                     VTPLPEETPITKTSTSEATDNLVEGKETEKQTEEIADTSPTPVSTEEDTTSSEPNAEE
                     TTLRTANNDNQDTTEEKSAVPTIDTVTLETKTVYLSEAVTITESITLPDTTEKIEWTL
                     DGKSISEWKTWNLKEGDFTGDTFITVEESRQDNQLHLNIQLAALFGEDLSKRTPSNIR
                     RTYRHFIKNMLLEGTSADGNLIISKTLHFRPYEAYRTHEEMLTEIEETKNNAATDRLV
                     RIESIGQSAEGRDIKMAVVAKDQASIDKYLTETTPLMLTQPDQMLKQLQAGTFDYKLP
                     ILINNTHADEQPGIDVVTSLFKEFAQKDTITFPSTDADGNPVTLHLKVTDLLDKFIFL
                     FNFTENPDGDVKNLRSLVNGLDPNRDTGFQVNPETQAIVRQIHKWNPISVLDIHGFVS
                     GFLIEPATPPHDPNFEYDLLADIMLEKAHEMGRAGIANSKYERYTIPKVHWGDGWDDS
                     FSGYTAVYAMYHGILGHTIEIPEGNQESFKAGFFAVLGGVHNMATKPDSLMEMRLKYY
                     SRGVNKVEDPKAESELVGPDGAVVGRVKKDQPKFFPDYYVIPMTLDKHNDMQEAFKMI
                     EYFNRNGVVVKELTEDVGNFRKGDLVVDMAQAKRGFANHVLYAGSDESAWGAMYAELV
                     VNFPDMKGFSAKAVFEENTFSGKLGSITWTKAPRTTEIDFKAPYYVVANTSESAVQAI
                     NQAIKSGAKVYLTDDGYIMETNQFSHLLDTYALYGEPLYKKPLGQELKAMKVYAPSHS
                     YSWAGDFAILANAALAVERMGFEIVNSADEADAIILESDQFDASVFGKKPIIIVGGVA
                     MQKLEELGILAGFNAEQFTDGGDYEGLMRAIIDDKDPLTSGYAMNGLFYSNSGNWIEG
                     IPEGFKTLVKIADKDYYIAGWWPGHDKLANKIVAIAGNYQDQPVFIYAGNPTNKVHPV
                     HFFRWVSNALFGSQLASLEDLPAVEILVPQPEMPKNILDEAPKTTTVVHTTKSTEAKQ
                     LPQTGEKTNYIAIALGSLLLGSIALRRKERS"
BASE COUNT         2483 a         1910 c         2128 g         2761 t
ORIGIN      
        1 aaaaaacaat caccatttat aattgcagga atcgtcatgc taggggtcgt gatgcgtgcc
       61 ccctttacag ctttgcctgc tattttgata gatgtggcag caggactgag agtagaagtg
      121 agttcattag gaattttaac ctctattccg ctcatcatgt ttgctctctg ttcatcctta
      181 gcaccgcgtc ttgcggctaa gtttggcatg gaaaaactaa tggccctagt cttactggtt
      241 atggtgctgg gttcaggaat gcgagttctc aacttaccag ccctttacat tggtacaatg
      301 cttgttggtg ctacaatagc atttattaat gttttgctac caagtttggt tgcggctaat
      361 tttccaaaga aaattggtct gtatacgacg atttatatca ctctcatggg ggtggcggca
      421 acagttgcat ctatgattgc tgttccaatt gtatcctcta gttcttggga attttttatt
      481 ctattaatta caggattggt gtttatggct ttcctgatct ggttgcctaa tgtaaaaaat
      541 aaccatcgat ttgcaagtga gaaccaagga aaccagaaat catctatctg gaaaaataaa
      601 gcagcgattg cctttttgat atttggtggg ctacaatcag tcctctacta tacagagatt
      661 acctggttgc caactatttc tcaatcagtt ggctttagta aggcagaagc agggctaatg
      721 gctggtttct tcaatatgac agctattccc atgtctatga ttatcccagc tgttctttct
      781 cgtcagacaa aagaaatgcg tcgaaatatc atgctggcta tttcatctgt taccttactt
      841 ggtttgttca tgatgtcatt gattccgacc aatctcattc tttggtcagc acttcacatt
      901 attttaagtt tttcaaatgc agccctcttc ccttatatga tgttgagctt tactttgaaa
      961 acaagcaaca gccaggctac tgcccagtta tcaggaatgg tgcagacagg tggctatctc
     1021 attgcagcat ttggaccagg ccttctcggt tacagctatc caatcttcgg aaactggatg
     1081 ccattgattc ttgctctggc tatcgtcaca cttgccatga tgtggactat tgttctcatt
     1141 gaaagagaag atattatctt ataaagtata atcccttaag aaggctggca tttttctgtg
     1201 aaaatggcag agcttctaag ggattttttg tcaaacaaaa aaagctggac atttgccagc
     1261 tttttaatgt gccacacgtt tacgagcagc ttttttacga ttttcctcaa tgaaagcttc
     1321 tttcttttct tctggttcaa tgattgtttt gtgaacagtg aagactgcgc ctgctgcaag
     1381 agcaactgta gaaagaacac ctgtcaagaa acctttacca aaacctttag ccatagttat
     1441 ttctccttta cttgtgttat aatagatttt agcgaaaaaa caaaatattt tcaaggaaaa
     1501 agatgaaaac taaagttatt gtggtcatag gaccgacagc ggtaggaaaa actgcccttg
     1561 gcatagactt ggcccagcgc tacaatggag aaattatcag cggtgatagc cagcaagtct
     1621 atcgcaaact ggatattggt acggcaaaag ctagtcctga agagcaggct gctgcggttc
     1681 atcacttgat tgatgtccga gatgtgaccg agggctattc ggcttatgaa tttgtagcag
     1741 aagccaaggc tctgattgct gacattaaaa gtcgtggcaa gttgcctatt atcgtgggtg
     1801 ggacagggct ttacattcag agcttgcttg aaggctacca tctgggcggg ctggttgacc
     1861 aggagcaggt acttgcttat cgggcggaac tcgactgctt gtctgacgag gatttggaaa
     1921 caatggcaga gcaggcaggt ttgatggtcg agggaaacag ccgacggaga atcattcgtg
     1981 gactggaatt gaaaaaattt ggcgaaaact tagaaaatac agagtcagga tatgagcctc
     2041 tttacatctg cctgacggat gacagacagg ttctttacga ccgcatcaat cagcgagtgg
     2101 ataagatgat ggcggcgggc ttactggatg aagttagctg gctctaccaa gaacacccag
     2161 aagctcaagc tgctatggga attggctaca aggagttttt cccctactta gaaggtcaaa
     2221 tcagcctaga agaagcaatt gataatgtca aacaaaatag ccgccgcttt gccaaacgcc
     2281 aattaacctg gtttagaaac cgcatggcag tcgattttta ccaagtatca gaagaagctg
     2341 ttaaggatag gatttacacc gctgtggagg aatttttaga tgattgaaac ccagaaagaa
     2401 caagaacgtg ccctcctggt cggagttgaa ttgcagcaga cagataattt tgacgtgtcc
     2461 atggaagagt tggcaagcct ggctaagacc gctggggccc tcgtcaaagg agtatatacg
     2521 cagaagcggg agaaatatga cagcaagact tttgtcggtt ctggtaagct ggacgaaatt
     2581 gcccagatgg tcgaagctga cgagattgat actgtcatcg tcaacaatcg attaacaccc
     2641 cgccagaatg tcaatctgga agagatttta ggtgtcaagg tcatcgaccg tatgcagctg
     2701 attttggata tttttgccat gcgggcacgg agtcacgaag gaaaactgca ggtccaccta
     2761 gcccagctca agtacatgtt gccacgcttg gttggacagg gcatcatgct cagccgtcag
     2821 gcaggtggta tcggctctcg tggaccaggt gaaagccagt tggagctcaa ccgtcgaagc
     2881 attcgcaacc agattcatga cattgagcgc caactcaaaa cagtggagaa gaaccgagcg
     2941 actgtccgtg aacgccgttt gcaatcaggc gtgttcaaaa tcggcttgat tggctatacc
     3001 aacgcgggta agtccactat tatgaatgcc atgacggaca agcgacagta cgaggctgat
     3061 gaactttttg ccacactaga tgccacaacc aagcagatta acttggcaga caaatttaat
     3121 gtgaccttga ccgatacggt tggtttcatt caggacctgc cgactgagtt gatttctgcc
     3181 ttcaagtcca ccttggagga gtccatgaac gtggatctct tgctccatat catcgacgcc
     3241 tctgacccca atcacagtga gcaggagcag gtggtcttgg acattctaaa agacctggat
     3301 atgctggaca ttccacgtct agctctctac aacaagctgg acaagaccga tgacagcttt
     3361 acccccagtc agtttcctca tgtcatgctg tccactaagg atgaaaatgc caaaggccat
     3421 attcagatga tggtcttggc caagataaag accatgtttg aacgatttga ggtcagggtg
     3481 ccacttgctg aatcttataa attgcatgat ttagctactc tggctctgat tgaaaatcgg
     3541 acctacgaag aggatgtgga agtggtatca ggctatatcg cttccagcaa taaatggaag
     3601 ttggaagaat tttatgacgg attatcttga tttggcaatc aaatacggtg gttttaccag
     3661 cctggacaag gtctatctgg ctaggaaatt ggctgatatg actgaccaac aaaaactaga
     3721 ttttatcacg ccaccgcctt cggttatcaa tgcctatttt gcggaaatct accagaaaca
     3781 aggggcagaa gaggcgacgg actactatct cactctttct cagcagctct gcctttttcc
     3841 aaaagaaccc agctttgctg aaagcaagcc ctttgtccgc ctgaatttat ctggtaagtc
     3901 tttcggattt acctatgtgt cggcggacgg tctggcccag gttttttcgg aagtaggaga
     3961 ggaagtgacg gatagcttgc tctttgaaat cgcccaagtc tttccccact atgtcgtctt
     4021 tgtggaggag ggcaagattt ttatgaaagt caatcccttt gaggacgccg agttagagga
     4081 ggttgaaaca gactaccttt taacccaggt ggcaaccgga gaaggcttgg tcaagatttc
     4141 aggctttaat caggaagaag tgctggaagt ggcggacggc tatgctggtc agcattacta
     4201 tgtctggtcg ggtcgctctg caattttata tataaaacat tagaaagtaa acaatgcaaa
     4261 ttcaattttt aggtacgggg gctggtcagc cctccaaggc tcgaaatgta tccagtttgg
     4321 ccttgaaact cttggatgaa atcaatcagg tttggctctt tgactgcggt gagggcactc
     4381 agaatcggat tttggaaacg accattcgtc cacgcaaggt ggctaaaatc tttattaccc
     4441 acctgcacgg tgaccatatt tttggcttgc ctggtttcct gtctagccgt tctttccagt
     4501 ctagcgagga gcagacagat attgatattt atggacctgt tggtatccgt tcttttgtct
     4561 tggcaagtct taaagtatca gggacacgcc taccttatcg cattcatttt catgagtttg
     4621 atgttgatac ggtaggtcag gtcctagaaa cagacaaatt cacggtattc gctgaaaagc
     4681 tggaccatac cattccttgt gtcggctatc gtgtcatcca gaaagatttg gaagggacat
     4741 tggatgcaga ggctctgcgc gcggcaggtg taccatttgg tcccctattc ggtaaaatca
     4801 aaaatggtca aaacgtgacg ctagaagatg ggactgaaat tatcgcgagt gactatattt
     4861 ctcctcctcg gcctggtaag gtagtgacca ttcttggtga tacgcgcaag tgccatgcca
     4921 gtgtacgctt ggctgttaat gctgatgtgc tggtgcatga ggcgacttac ggaaaaggcg
     4981 atgagaagat tgctcgcaag cacgggcatt cgaccaatat ggaagccgct caggttgcca
     5041 aggatgcagg tgtcaagcag ctcttgctta atcatatcag tccacgattt ttatccaagg
     5101 atattagtca attacggaaa gatgcaagta ctattttcga gcaggttcat attgtcaaag
     5161 atttagagga aattgagcta tgagaaccat tctaatcaca ggtgcctctg gtggtttggt
     5221 acaggaaatg gtgccattgc tgaaagatga ttttttgatt ttactaggtc gtgatgtggc
     5281 aaaaattgag cagctctatg cttaccatga aaaaaaggct gtctttgatg tagacatccg
     5341 agacgaaata gctctgacgg cattttttga tgaactggat agtcagtttg gtcagattga
     5401 tattctagtc aataatgcag gctatgccat ttacgatgat tttgagaatt tttccagcca
     5461 gcaggtgcag gccatgtttg atatcaatac ttttgctctg atgaccatgt gccgtttagt
     5521 aggtaaacga atgaaggcaa gacggagcgg gcagattatc aatatcattt ccatgtcagg
     5581 cttgattgct tcagctaagt cctcggtcta ttcagcgacc aagtttgcgg ccatgggttt
     5641 ttctaatacc attcgcttgg aattagccca gtatggtgtg acagttacaa cggtcaatcc
     5701 aggtccaatc gcaaccagct ttttcgatca ggctgacccg gatggaagct atcaagagag
     5761 cgtcaaggct ttcttgctgc aaccagacta tgttgccaag aagattgttt cagctatggg
     5821 gacgaagaaa cgagacatca atctgccttg gtcactagca gctgctcata aactctatac
     5881 tctctttcca agaatagcag actacttggc cagtacagta tttaatttaa aataagcata
     5941 gaaaaacgcc gaaataaaac tcggcgtttt cgtgtagact agctacgctc ttttctacgt
     6001 aaggcgatac tgcctagaag taggctacct aatgcgatag ctatatagtt tgttttttca
     6061 cctgtttgag gtagttgttt tgcctcggta gacttggtgg tatgtactac tgtagtagtt
     6121 tttggcgcct catccagaat attttttggc atttcaggtt gtggtacaag aatttctaca
     6181 gctggtaagt cttctaagct tgctaattga ctaccaaata gggcgttgga cacccaacgg
     6241 aagaagtgaa cagggtggac cttgtttgtt ggattacctg catagataaa gacaggttgg
     6301 tcttgataat ttccagcgat ggcgacaatt ttattggcta atttgtcatg accaggccac
     6361 caacctgcga tataataatc tttatcagcg attttaacaa gcgttttaaa tccttcagga
     6421 atgccttcaa tccaattacc ggagttggaa tagaaaagtc cattcatggc gtagccactt
     6481 gttaatggat ctttatcatc aataatagcc cgcatgagac cttcatagtc accaccatct
     6541 gtaaattgtt ccgcattgaa acctgctaag attcctaatt cctccagttt ttgcatggcg
     6601 acaccaccta cgatgataat tggtttctta ccaaatacac tggcatcgaa ttggtctgat
     6661 tcgagaatga tagcatcagc ctcatctgcg ctattgacaa tttcaaagcc cattcgttct
     6721 accgcaagtg cagcatttgc aagaatggca aagtcgcctg cccaactata agagtgagaa
     6781 ggagcgtaca ccttcattgc tttcaattct tgtccaagag gcttcttata gagaggctcg
     6841 ccgtatagag cataggtgtc cagtaagtga ctaaattggt tagtttccat gatgtagcca
     6901 tcgtctgtaa ggtagacctt agcgcctgat ttgatggctt gattaatggc ctgaacggcg
     6961 ctttcagagg tgtttgcaac gacataataa ggcgctttga aatcaatttc cgtagtacgt
     7021 ggagcttttg tccatgtgat gctacctaat ttgccgctaa aggtgttttc ttcaaataca
     7081 gccttggcgc taaagccttt catatctggg aagttgacca ccaattcagc atacatggct
     7141 ccccaagcag attcatcaga accagcgtag aggacatggt tagcgaatcc tcgtttggct
     7201 tgagccatat cgacaactag gtcgcccttg cggaagtttc caacatcttc agttaattcc
     7261 ttgacaacaa ccccattacg attgaaatat tcaatcatct taaatgcttc ttgcatatcg
     7321 ttgtgtttat cgagcgtcat aggaatcaca tagtagtctg ggaagaattt tggctggtct
     7381 tttttgacac gtccgacaac agctccgtct ggtccgacta gttcagactc tgcttttgga
     7441 tcttctacct tattgacacc gcgtgaatag tatttgaggc gcatttccat aagactgtct
     7501 ggtttggttg ccatattgtg aacaccgccc aaaacagcaa agaatcccgc cttgaatgat
     7561 tcttgatttc cttctggaat ttcaatcgtg tgtccaagaa taccgtggta cattgcatac
     7621 accgctgtat agcctgagaa ggaatcgtcc caaccatctc cccagtggac tttagggatg
     7681 gtgtagcgtt catatttaga atttgcaata cctgctcggc ccatttcatg agctttttcc
     7741 agcataatat cggctagtaa atcatattca aagttcgggt catgtggcgg agtggcaggc
     7801 tcgatgagaa atccagatac aaaaccatga atatctaaaa cagatattgg attccatttg
     7861 tggatttgac gaacgatggc ttgtgtttct ggattcactt ggaaaccagt atcacggtta
     7921 gggtccaaac catttactag tgaacgcaag tttttaacat cgccatcagg attttctgtg
     7981 aaattgaaca agaagataaa tttatctaac aaatctgtca cttttaaatg aagagtaaca
     8041 ggatttccat cggcatctgt agatggaaag gtgatggtat ctttttgtgc aaattctttg
     8101 aataggctag ttaccacatc tatgccgggt tgttcgtcag catgagtgtt gttgatgaga
     8161 ataggtaatt tatagtcgaa ggttccagct tgcaactgtt tcagcatctg gtcgggttgg
     8221 gtcagcatga gtggtgttgt ctcagtaaga tatttatcaa tacttgcttg atctttagcc
     8281 acaacagcca ttttaatgtc tctaccttca gctgattgac caattgactc aatccttact
     8341 aggcggtcgg tcgcagcatt atttttcgtt tcctcaatct ctgtcaacat ttcctcatgt
     8401 gtacggtagg cttcataagg acggaaatga agagtttttg aaattatcaa gtttccatcg
     8461 gcactagtac cttccaacag catatttttt ataaaatgtc gataggtacg gcgaatatta
     8521 ctcggtgtcc gtttactcaa atcttctcca aagagagctg cgagctggat attcaaatga
     8581 agttggttat cctgtctgct ttcttctact gtgataaaag tatctcctgt gaaatctccc
     8641 tctttcaaat tccaggtttt ccattcggaa atagactttc catccaatgt ccattctatt
     8701 ttttcagtcg tatctggaag tgtgatggat tctgtgatag tgactgcttc cgatagatag
     8761 acagtttttg tttcgagtgt aactgtatca atagtcggta cggcagattt ttcttctgta
     8821 gtatcctgat tatcattatt agctgttctg agcgtagttt cctcggcatt gggctcggaa
     8881 gatgttgtat cttcttctgt ggaaacaggt gtgggagaag tatctgctat ttcttcagtt
     8941 tgtttttctg tctccttccc ttctacaaga ttatctgtag cttcgcttgt gctagttttc
     9001 gtaataggag tctcttcagg cagtggagtc actgtttcac tagtagtagg tggtatctcc
     9061 tctgtatttg cgaagaccgt tccctgagcg agagatgcag ctaaaagaac tgttgaggca
     9121 agtaggactt gattcaacag ccttttctta tatgaaagtt tcatgcgaac ttcctccttt
     9181 tgataatgtg tacggggtaa taaattaaaa cgggttattt catgcctatc ttatcaaaaa
     9241 atatatgtct ttacaatata aattgaatat gtttatatat tt
//
LOCUS       DBNFCO010000067         9146 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.067, whole genome shotgun sequence.
ACCESSION   DBNFCO010000067 DBNFCO010000000
VERSION     DBNFCO010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9146
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.067"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(502..1395)
                     /locus_tag="AC1PIV_001544"
     CDS             complement(502..1395)
                     /locus_tag="AC1PIV_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HIP6612558.1"
                     /translation="MLELKNENLTVQFSELGGQIISIKDKDGIEYLWQGEPTYWSGQA
                     PVLFPICGSLRNDWAIYEPAERPTFTGTIPRHGLVRKMLFKNVKSTENSLEFSISSNE
                     ETVKNYPFEFELSINYSLFGKTIRIEYRVKNLEGHRKLPYFIGGHPGFNCPLLDGESY
                     EDYYLEFEKVESCTVPRSFPETGLLDLRDRRPFLENQKTLDLSYKLFEYDAITLDQLA
                     SRKVTLKSKNHQKKLSIAFDDFPYLVIWSTTNQSPFIALEPWSGLSTSLEESDIFNAK
                     RNISYVAPKEVDTKYFDIIIE"
     gene            complement(1460..2866)
                     /gene="lacG"
                     /locus_tag="AC1PIV_001545"
     CDS             complement(1460..2866)
                     /gene="lacG"
                     /locus_tag="AC1PIV_001545"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HIP6612559.1"
                     /translation="MVKTLPKDFIFGGATAAYQAEGATKTDGKGRVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLELSEQFGVNGIRISIAWSRIFPTGFGEVNPKGVEYYHKLFAE
                     CHKRHVEPFVTLHHFDTPETLHSNGDFLNRENIEHFVNYAAFCFKEFPEVSYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHAKAVKLYKDAGYSGEIGVVHAL
                     PTKYPYDPTNPDDVRAAELEDIIHNKFILDATYLGYYSEKTLEGVRHILKVNGGELDL
                     RDEDFAALDAAKDLNDFLGINYYMSDWMRAHDGETEIIHNGKGEKGSSKYQIKGVGRR
                     ESPVDIPKTDWDWIIYPQGLYDQIMRVKNDYPNYKKIYITENGLGYKDEFVDGTVYDD
                     GRIDYVKKHLEVISDAISDGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAYWYKKVAETQVIE"
     gene            complement(3111..4790)
                     /locus_tag="AC1PIV_001546"
     CDS             complement(3111..4790)
                     /locus_tag="AC1PIV_001546"
                     /EC_number="2.7.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0019197 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase complex [Evidence IEA];
                     GO_function: GO:0015155 - lactose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactose-specific PTS transporter subunit EIIC"
                     /protein_id="HIP6612560.1"
                     /translation="MNKLIEFIEKGKPFFEKISRNPYLRAIRDGFIAAMPVILFSSIF
                     LLVAFVPNIFGFTWSDEAVAAIMKPYGYTMGIVAVLVAGTTAKSLTDAFNRQLPKTNQ
                     INFISTMIASISGFLLLASDGIEGGFANGYMGTKGLLTAFLAAFITVNIYKVCVKNNV
                     TIRMPDEVPPNVSQAFKDVIPYALSIFVLYGIDLVTRQFLGTNVAEAILKLFEPLFTA
                     ADGYVGITIIFGAYALFWFVGIHGPSIVEPAIAAITYANIETNFQLLQAGQHADKILT
                     SGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNKAIGRASVVPTFFGVNEPILFGAPLV
                     LNPVFFVPFILAPIANVWIFKFFVDTLKMNSFSVNLPWTTPGPLGIVMGTNFAPLAFA
                     LAILLVFVDVLIYYPFLKVYDEQILAEEQSGKVENSLKEKVAANFNTAKADAILEKAA
                     VETEISEQTNVLVLCAGGGTSGLLANALTKAAKEYGVPVTATAGSYGAHREILPEYQL
                     VILAPQVASNYDDIKQETDALGIKLAKTEGAQYIKLTRDGQGALDFVKQQF"
     gene            complement(4790..5107)
                     /locus_tag="AC1PIV_001547"
     CDS             complement(4790..5107)
                     /locus_tag="AC1PIV_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HIP6612561.1"
                     /translation="MNREEITLLGFEIVAFAGDARSRLMEALAAAQKGDYAKAEELVE
                     AANACIVEAHHAQTSLLQKEAAGEDLAFSVTLMHGQDHLMTTLLLKDMMSHMIELYKR
                     GDK"
     gene            complement(5139..5972)
                     /locus_tag="AC1PIV_001548"
     CDS             complement(5139..5972)
                     /locus_tag="AC1PIV_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017770255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HIP6612562.1"
                     /translation="MFRIIQSLNNNAALVKNEHGEQAVVMGLGITFQKKKGDLIIKDK
                     IENIFSLKNDEAKENFLTLLKDIPLDFISATYTVINHLVETYHYPVQEYLYVTLTDHI
                     YCAYQAVLKNTYQESRLPNISAEYPLEYKMAREALAMFREKLLNDFPNDEIGKIALHL
                     INAKGETIHPTSEEHDISKKIIAEVEQILIDNGIRRSKENSNFYDRFMIHLSYFLNYL
                     DRSHQSNESIASLEQYIKLQNPRAHQVGSQIFEMITSLVDEPVNDSERFYIVLHIQRL
                     L"
     gene            complement(6161..7138)
                     /gene="lacD"
                     /locus_tag="AC1PIV_001549"
     CDS             complement(6161..7138)
                     /gene="lacD"
                     /locus_tag="AC1PIV_001549"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HIP6612563.1"
                     /translation="MVVTADKRKYMEKVSNEAGIISALAFDQRGALKRMMAKHQTEEP
                     TVEQMEELKKLVSEELTQFSSSILLDPEFGLPASRARDEQCGLLLAYEKTGYDTSSTS
                     RLPDCLVEWSVKRLKEEGADAIKFLLYYDVDGDPYVNLQKHAYIERLGSECQAEGLPF
                     FLEILSYDETIEDNASVEFAKVKPRKVNEAMKVFSDERFGVDVLKVEVPVNMNFVEGF
                     GTGEVVYTKEEAAEYFRQQEASTHLPYIYLSAGVSAKLFQDTLVFAHEAGAKFNGVLC
                     GRATWAGVVPVYIEHGEEAAREWLRTVGRENIEGLDVVLSQTATSWLEK"
     gene            complement(7140..8073)
                     /locus_tag="AC1PIV_001550"
                     /pseudo
     CDS             complement(7140..8073)
                     /locus_tag="AC1PIV_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250260.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0009024 - tagatose-6-phosphate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
     gene            complement(8083..8598)
                     /gene="lacB"
                     /locus_tag="AC1PIV_001551"
     CDS             complement(8083..8598)
                     /gene="lacB"
                     /locus_tag="AC1PIV_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HIP6612564.1"
                     /translation="MKIAIGCDHIVTYEKIAVVDYLKNQGYEVLDFGTYDNVRTHYPI
                     FGKKVGEAVVSGQADLGICICGTGVGINNAVNKVPGVRSALVRDMTSALYAKEELNAN
                     VIGFGGKITGELLMCDIIEAFIKAEYKPTEENKRLIEKIAAVETLNQEQANPEFFTEF
                     LEKWDRGEYHD"
     gene            complement(8625..9047)
                     /gene="lacA"
                     /locus_tag="AC1PIV_001552"
     CDS             complement(8625..9047)
                     /gene="lacA"
                     /locus_tag="AC1PIV_001552"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050044 - galactose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HIP6612565.1"
                     /translation="MTIIIGADPAGSKLKDVIKDYLLEKSYDFKDVSDGSDFVDTTLA
                     VVAEVNQQEGNLGIVIDAYGVGPFMTATKVKGMIVAEVSDERSAYMTRGHNNSRIITI
                     GSEIVGEGIAKNIVKGFVEGEYDGGRHQIRVDMLNKMC"
BASE COUNT         2765 a         1946 c         1476 g         2959 t
ORIGIN      
        1 tatcatgcca ctcatcgttt acaattttta ctatttcaag tgcagcaatt attgatccaa
       61 gttcaagtat catagtatga aaatgaatca ttattttaga gtcatcatct ggtaattcat
      121 cagcgaaatt ttttcctaca aaatctttta aatcacaatc attcataagc taacacctat
      181 ttaataaatc ttcttacttt tactcaaact gataattcat tctgcttcaa aaatattttc
      241 gagattacaa gcatatgtaa tgtcctctct cactaagtat atcatacccc ataggaatac
      301 atctactacg atttttgtat cgctttatca tctcgtaatt aagtcattga taaagttttc
      361 tcaaaataca gctgaacacc ctgcaacact taatttaatt tttcataata ttaaattaag
      421 caataaaccc cactgactta ttcagccagt ggggtttttg agtgttttcc gtagaatatt
      481 taaattactt aactatggta tttactcaat aataatatca aaatattttg tatcaacctc
      541 ttttggagcg acgtaactaa tatttcgttt ggcattgaat atgtcagatt cttccagtga
      601 tgtagagagt ccgctccatg gttctaatgc gataaaggga ctctgatttg tagttgacca
      661 aatcactaaa tatggaaaat catcaaatgc aatcgaaagt ttcttctgat gattttttga
      721 tttcaaggtt acctttcgtg atgctaattg atccaatgtt atggcatcat actcaaacag
      781 tttataggac aagtccaagg tcttctgatt ttccaagaat ggccggcgat ctcgcagatc
      841 aagtaagcca gtttctggaa aacttctagg tactgtacaa gattctactt tttcaaattc
      901 taaataatag tcttcataac tctcaccatc caacaaggga caattaaaac ctgggtgacc
      961 cccaataaag taaggtagct ttctatgtcc ctcaaggttt ttcacccgat attcaattcg
     1021 aattgttttg ccaaatagtg agtagttaat agaaagttca aattcaaaag ggtaattttt
     1081 tacggtttct tcgtttgatg aaatagaaaa ttctaaagag ttttcagtac tttttacatt
     1141 tttgaacagc atttttctca caagtccatg ccttggaatt gtgcctgtaa atgtcggtct
     1201 ttctgcaggt tcatagatag cccaatcatt tcgtaaactt ccacaaatcg gaaatagaac
     1261 tggtgcttga ccgctccaat aggtcggttc tccttgccaa agatattcga taccatcctt
     1321 gtctttaata gaaataattt gcccacctaa ttcagaaaat tgtactgtta agttctcatt
     1381 ttttaattcg agcatataaa ctgcctccct tatatgaaaa caaggatgct aacttgagat
     1441 aggcatcctt gtattagttt tattcaataa cctgtgtttc cgctactttt ttataccaat
     1501 aagcactttt ctttggataa cgttcttggg tctcaaagtc aacatagaac aatccatatc
     1561 gtttctcgta tccatttgac caagaaaata catccatcaa ggaccagatg aaataacctt
     1621 taacattggc accatctgag atagcatctg aaatcacttc taaatgcttt ttcacataat
     1681 caattcgacc atcgtcgtag actgtaccat ctacaaattc atctttatag cctagaccat
     1741 tttcagtgat gtagattttc ttatagtttg gatagtcatt ttttacacgc atgatttgat
     1801 cataaagacc ttgtgggtag ataatccaat cccaatccgt tttcggaata tcgactggag
     1861 attctctacg accaactccc ttgatttgat acttagaact tcccttttca cctttaccat
     1921 tatggataat ttccgtttct ccatcatgag ctctcatcca atcactcata tagtaattga
     1981 tgcccaagaa gtcgttcaaa tcttttgcgg catctaaggc agcgaagtct tcatcacgaa
     2041 ggtctaattc cccaccattt actttcagaa tatgtcgaac gccttcaagc gttttttcag
     2101 aatagtaacc caagtatgta gcatcgagga taaatttatt atgaataata tcttctagtt
     2161 ccgctgcacg aacatcgtca ggattggttg gatcataagg atatttcgtt ggcaatgcgt
     2221 gtacaacacc aatttctcca ctataaccag catccttgta aagcttaaca gccttggcat
     2281 gtgaaaccat catattgtgg tgagattgga ataccttagc taagtcatac tgaatccctg
     2341 gtgggaactt cccaactaga tattgcccat caccaattgg accgatttca ttaaaggttg
     2401 tccagtaact aacttcaggg aattctttga agcaaaacgc tgcgtaattg acgaagtgct
     2461 caatattttc tcgatttaga aagtcaccat tagaatgtag cgtttctggt gtatcaaaat
     2521 ggtgaagcgt tacaaatggt tctacgtgac gcttatggca ttccgcaaat aatttatggt
     2581 aatactctac tccctttgga ttcacttctc caaagcctgt tgggaagata cgagaccacg
     2641 caattgaaat ccgaatgcca tttaccccaa actgttcact tagttctaaa tcaactggat
     2701 aacgattata aaaatcagaa gctggttccg cagtgtacca gtaattatct tctagatact
     2761 tgtcccacgc aacacgacct tttccatctg tctttgtggc accctctgct tgatatgcag
     2821 cagttgctcc accaaatata aaatctttcg gtaatgtttt aaccatatgc ctaccttctt
     2881 ctatcaaaaa taaataaagg ggtaggagtt ggagatgata actccctccc cttttgatta
     2941 agaacctgta ttcacaagtg aagtgcttgt atatacttgt atataagaga tagtttttcg
     3001 ctaatcaagg cgtttttttg agggaatact gactgtattt tgaaaaaaac taacgatgag
     3061 tagctgaaaa actagcctta gatggaagtg ctgaactgtg aatataggtt ctaaaactgt
     3121 tgtttgacaa agtcaagagc accttgacca tctcgtgtga gtttaatgta ttgagcccct
     3181 tcagttttgg caagtttaat acccaatgca tcggtttctt gtttaatgtc atcgtagttt
     3241 gatgctactt gaggtgcaag gatgactaat tgatactctg gcaaaatctc acggtgcgcc
     3301 ccatagcttc ctgctgtagc tgtaactgga acaccatatt cttttgcagc tttagttaga
     3361 gcgttggcaa gtaatccact tgtaccaccc cctgcacaaa gtaccaaaac attagtttgt
     3421 tcagaaattt cggtttcgac tgcagccttt tcaagaatag catccgcctt ggcagtatta
     3481 aaattagctg ccactttctc tttcaagcta ttttcaactt tccctgattg ttcttcagca
     3541 agaatttgct catcataaac tttcaagaat ggataataga taagtacatc gacaaatacc
     3601 aacaaaatag ctagtgcaaa ggcaagtgga gcaaagtttg ttcccattac aatccccaat
     3661 ggtcctggag ttgtccatgg caagttaacg ctgaaactgt tcatttttag cgtatcaaca
     3721 aagaatttga aaatccatac gttagcaatt ggagctaaga tgaatggaac aaagaatact
     3781 gggttgagta caagtggcgc accgaacaag atcggttcgt ttacaccaaa gaaagttgga
     3841 acaactgaag cacgtccaat tgctttattt cgtttagact tagtcaacca cataaacatg
     3901 aatggcacaa ccaaggtagc acctgtacca cccatagtca cgataaacat ttgagtacct
     3961 gaagtcagga ttttgtccgc atgttgaccg gcttgtaaaa gctggaagtt ggtttcaata
     4021 ttagcataag taatggctgc aattgctggt tccacaatag atggaccatg aatccctaca
     4081 aaccagaaca aagcataggc accaaagata attgtaatac caacataacc atctgcagct
     4141 gtaaacagag gctcaaataa tttcagaatc gcctcagcaa cgtttgttcc aaggaattga
     4201 cgtgtcacaa gatcaattcc atacaagaca aagatagaca atgcatatgg aatcacatct
     4261 ttaaatgcct gggatacatt cggtggaact tcgtctggca tacgaatagt gacattgttt
     4321 ttcacacaga ccttatagat attaaccgta atgaaggctg ctagaaaggc tgtcaaaagt
     4381 cccttagttc ccatgtaacc attggcaaat ccaccttcaa taccatcaga agccagtaat
     4441 aagaaacctg aaattgaggc aatcatggtt gaaatgaagt taatctgatt ggtttttggc
     4501 aattgacggt taaacgcatc tgttaaagat tttgcggtcg ttcctgcaac taagacagct
     4561 acaataccca ttgtataacc gtaaggtttc atgatagctg caactgcttc atctgaccaa
     4621 gtaaaaccaa agatattagg aacaaaagcc accaatagaa agatacttga gaacaagata
     4681 accggcatgg cagcaataaa accatcacgg atagccctta aataagggtt tctcgaaatc
     4741 ttttcaaaga aaggcttccc tttctcaatg aattcaatca atttattcat tacttatcac
     4801 ctcgtttgta aagttcaatc atatgactca tcatatcttt caataacaac gttgtcatga
     4861 gatggtcttg accatgcatg agcgtcacac taaaggctaa atcctcacca gccgcttctt
     4921 tctgcaacaa acttgtctga gcatggtggg cttcaacaat acaagcattg gccgcttcaa
     4981 ctagttcttc tgcttttgca taatcacctt tttgagcagc agccagtgcc tccatcaaac
     5041 gagaacgagc atcaccagcg aatgcaacaa tctcaaaacc taataacgta atttcttctc
     5101 tgttcataat atgaacctcc ttttaaaatt gaattgattt acaataaccg ttgaatatgt
     5161 aacacaatat agaacctttc actatcattt actggctcat caaccaatga tgtaatcatc
     5221 tcaaaaatct gacttccaac ctgatgggct cttggattct ggagcttgat gtactgttcc
     5281 aaactagcaa tcgattcatt tgactgatgg gatctatcta agtaattcag aaaataggac
     5341 aaatgaatca taaagcgatc ataaaaattg ctattttctt ttgagcgtct aatcccatta
     5401 tctatcaaaa tttgttcaac ctcagcaata attttcttac tgatatcatg ttcttcactt
     5461 gtgggatgaa ttgtttcacc ttttgcattg attaagtgaa gtgcaatttt accaatctca
     5521 tcatttggaa aatcatttag caacttttca cgaaacatag ctaaggcttc acgcgccatt
     5581 ttatattcca atggatattc ggctgaaata ttgggtagcc tactttcttg ataggtattc
     5641 tttaaaaccg cctgatatgc acaatagata tgatctgtca gtgtcacata tagatattct
     5701 tgtacagggt aatgataagt ttctactaga tgattaataa ccgtgtaggt tgccgaaata
     5761 aaatctaatg gaatatcttt taataaggtt agaaaatttt ctttggcttc atcatttttt
     5821 agcgaaaaga tattttctat cttgtcctta ataattaaat cccctttctt cttttgaaag
     5881 gttataccta atcccatcac gactgcctgt tccccatgtt catttttcac cagggcagcg
     5941 ttattattta gtgactgtat aatcctaaac atatatccct cctatatttt taagcaaaaa
     6001 aagactacaa acaaaccgag aatatcctac tctcaaatcc atttgtagtc ttgcctaatc
     6061 gaattagtta caatccactc tattcttgct gatgagatta ttatagcata ttctcagaaa
     6121 atgtaaaccc tttcttttaa gaaaatggtt attttttcaa ttatttttct agccaagaag
     6181 ttgctgtttg agacaagact acatcaagtc cctcgatatt ttcacgacca acagttcgta
     6241 accattcacg cgcagcttct tcaccatgtt caatatagac tggcacaaca cccgcccatg
     6301 ttgcacgacc acaaagaaca ccgttaaatt tagcacctgc ttcatgtgca aacactagtg
     6361 tatcttggaa gagttttgca gaaacacctg cacttagata aatataaggc aaatgagttg
     6421 atgcttcttg ttgacggaaa tattcggctg cttcttcttt tgtataaacg acttcccctg
     6481 ttccaaagcc ttctacaaaa ttcatgttca caggtacttc taccttgaga acatccactc
     6541 caaatcgttc gtccgaaaat accttcatag cctcatttac ttttcgaggt ttgacttttg
     6601 caaattccac actggcattg tcttcaatcg tttcatcgta gctcaaaatt tccaaaaaga
     6661 atggcaaacc ttctgcctga cattctgaac ctaagcgttc aatataggca tgtttttgaa
     6721 gattgacgta tggatcccca tcaacgtcat agtagagtag aaacttaatc gcatctgccc
     6781 cttcttcttt tagtcgtttt acagaccact ctactaggca atctggtaat cgactagtag
     6841 agctggtatc atagccagtt ttttcataag ctaaaagtag accacattgt tcatcgcggg
     6901 cgcgcgatgc tggcaaacca aattcagggt ctaacagaat tgaggaagaa aactgtgtta
     6961 attcttctga aactagtttc tttagttctt ccatctgctc cacagtaggt tcttctgtct
     7021 gatgttttgc catcattctt ttcagggctc cacgttggtc aaaagctaaa gctgaaataa
     7081 tacctgcttc attgcttact ttttccatgt attttctttt atctgctgtt actaccatat
     7141 tatacctctt caacttcgat ttgagaatac aacgattctg cattttctaa attgacgtaa
     7201 cctgtctgtt cttcctgagc atttaacatg cctaaaacat tagcattttt taataattct
     7261 gcttcaggta aagcatgtac caaacctgct gcaatacctg caacagttga atctcctgat
     7321 cctactggat tgacaacttt gatttttgga attctgacac gatagaactt gtcattgtgc
     7381 ttggcaaaag ccccctttgc tcctaatgag acgactatcc aatcaattcc ttggaaaagt
     7441 tgatcagaca aaactgattt caactcttga atatcatcag taacttcttt accaatcagt
     7501 tgtgataact cttctgtatt cggcttaata actgtcggct tctgctggct ttctaaaacg
     7561 tttttcagcg cctcaccaga acaatccaaa acaacagcta caccgtattt tttacaaagt
     7621 tctacaatct caacataata attgctagca agtcccttag gcaaacttcc tgaaatgaca
     7681 actacatcta cattgttcag gacgatttca aggtgttcta taaaattcaa ggcttcatgt
     7741 tcttgaataa ttgggccttg ttctaaaatc tccgtctgtt tgccatcatg aagaatcgca
     7801 atgcaattac gtgtttcgct cccaatttcc acaaaggaat ttttaatatc atttcgagtg
     7861 agttgtttct ttacataact tccaatctca ccaccaataa aaccagtagc cactatatct
     7921 tcaccaattt gtttcaaaac tcgtgtgaca ttgagcccct tgcctccagc tgttttttga
     7981 acttttttct actcgattga ccgtatccaa atgaaaggta tccaagtgat aggcaatatc
     8041 aaccgacgga tttaaagtga ttgtcaaaat catgtgagcc tcctagtcgt ggtattctcc
     8101 acgatcccac ttttcaagaa attctgtaaa gaactctgga ttagcttgct cttgattgag
     8161 cgtttcaact gcagcaatct tttcaattaa gcgtttgttt tcttcagttg gtttgtattc
     8221 tgctttaata aaggcttcaa tgatgtcgca catgagcagc tcgcccgtaa tctttcctcc
     8281 aaaaccaatg acgttggcat ttaactcttc ttttgcatag agtgcagagg tcatatcacg
     8341 aaccagggct gatcggacgc caggtacctt gtttacagca ttgttgattc caacacctgt
     8401 tccacaaata caaattccca aatctgcttg cccgctcaca actgcttcac caactttttt
     8461 accaaagatt gggtaatgag tacgaacatt gtcataagtc ccaaagtcca atacttcata
     8521 gccttgattt ttcaaataat ctaccacagc gattttttca taggttacaa tgtggtcaca
     8581 accgattgca attttcatct cttattctcc tttgtttaca accattaaca cattttattt
     8641 agcatatcga cacgaatttg gtgacggcca ccatcatact caccttcaac aaatccttta
     8701 acgatatttt tagcaattcc ttctcctaca atctcactac cgattgtaat aatacgcgaa
     8761 ttgttgtgtc ctcttgtcat ataggcagag cgttcgtctg aaacttctgc aacgatcatg
     8821 cctttgactt tagttgcggt cataaatgga ccaacgccat aagcatcaat cacaatgcca
     8881 agatttcctt cctgttgatt aacttctgca actactgcca aagttgtatc aacaaaatca
     8941 cttccatcac tgacatcttt aaagtcatat gatttttcta gcaaataatc tttaataacg
     9001 tcttttagtt ttgagcccgc tggatcagca ccgataatga ttgtcataac ttatctccta
     9061 acaaaaatag aaagttgtag ccatatttgg cagaaaatct ttgttttgca aaacttagaa
     9121 aagcgttttc gctttttatg tttaaa
//
LOCUS       DBNFCO010000068         9072 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.068, whole genome shotgun sequence.
ACCESSION   DBNFCO010000068 DBNFCO010000000
VERSION     DBNFCO010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9072)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9072)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9072
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.068"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            49..1596
                     /gene="cls"
                     /locus_tag="AC1PIV_001553"
     CDS             49..1596
                     /gene="cls"
                     /locus_tag="AC1PIV_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HIP6612566.1"
                     /translation="MEKLWKIIYSRTFIVISLIILTIFLILWLVGSAATYMPALLIVL
                     QIFSIFVAISIINRPMNTSFKLTWIIFVIGIPIFGALFYFILQSNIETKRYRKNFHKQ
                     AQRLREYSKTSEKVMKALEQEDKEQLKLAHFMSEYVGYPIHTNTDAVYFSTGQEKFEA
                     LLEELKKAEQYIFMEYFIVDMGYMWDSILDILKEKAAQGVEVRFMYDGMNSLTNLPYN
                     YYKTLRKYGIKAKVFSQIIPALSTVQNNRDHRKIAIIDGKVAFTGGINIADEYINKKV
                     RFGYWKDAAIMIRGEAVANFTLMFLQMWNYNEKTETDDLKYLKTHKDLETETVDAEGF
                     FLPYGENPFDGDEVAKRVCLDMIQSATDYIYIMTPYLVLDDEMIDNLTYAAKRGVEVR
                     ILLPHIYDKKSAYLAARTDFPTYLEAGIEIFEFQPGFVHSKVVLVDDKKATVGTVNMD
                     FRSFYLNFECGLYIYNHSEVLAAIKDDFTHSFKKSQQINLLTFHKTYSWYKRLGGALL
                     RIISPLL"
     gene            1752..3965
                     /gene="recJ"
                     /locus_tag="AC1PIV_001554"
     CDS             1752..3965
                     /gene="recJ"
                     /locus_tag="AC1PIV_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008409 - 5'-3' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HIP6612567.1"
                     /translation="MIKPNYDWQLLTGFSDEQFIKIAKKEGVDPVAAKLLYERGIHSA
                     EELHTFLQPSLEDLHDPYLLHDMDKAVERIRRAIENYEHILIYGDYDADGMTSASILK
                     ETLEEMGAEVQVYLPNRFTDGYGPNQSVYKYFIEQQGISLIVTVDNGVAGHEAIAYAQ
                     EMGVDVVVTDHHSMQETLPNAYAIVHPEHPEGNYPFKHLAGCGVAFKLACALLETVHA
                     DLLDLVAIGTIADMVSLTDENRVMVKYGLSLLKQTERAGLQELIKIAGIDIDSIDEET
                     VGFQLAPRLNALGRLDDPNPAIELLTGFDDEEAHQIALMIDSKNVERKDVVQAIYDEA
                     KTMLRHDRPVQVLAKEGWNPGVLGIVAGRLLEELQQPVIVLSIEDGKAKGSARSVEAV
                     DIFKALKDHQDLFIAFGGHAGAAGMTLEVDKLEELALTLTDYIIENKLDLSSKSSLVL
                     DEELDLEELTLDTLKSFEKLAPYGMDNKKPVFYIRDFQVESARTMGQNNAHLKLRITK
                     GAAGFDVLAFGKGNLALEFSQAKGLELAVTLSVNQWNGNTSLQLMLVDARVNGVQLYN
                     IRGKQHPIPAGVPILDIENPVADNKAIVLANLPEDLSSLRSYFQEREFEAIYFKNEIA
                     KPYYLDGYGSREQFAKLYKTIYQFEEFDVRYKLKDLAVYLKIKDSLLVKMIQIFQELE
                     FVTIADGVMRVNKEAQKREISESQIYQELKETVIQQELMALGTVQEIYEWLCGRV"
     gene            3944..4840
                     /locus_tag="AC1PIV_001555"
     CDS             3944..4840
                     /locus_tag="AC1PIV_001555"
                     /inference="COORDINATES: protein motif:HMM:NF022755.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HIP6612568.1"
                     /translation="MAMWSRLMTVEALVVGVIGTLLYTYWFIRQKGLLKNLEQITEIK
                     HALIELRRVGWSERAIKKVFLKQLLPLKQEDIPAFVQNFIKEATIFASTSFYQLIRVD
                     SRSLSQEKATALLEQCMNMLDFPEELSHGILPELLQKMDVNCPPHHPFWRYFAKLVDK
                     AFPVRELEVKRPLNRQVHQLRYLISYQQTFWVRQQFGKGKTDWQALIAYVRSLPRWSY
                     RLRESARLHNKQLFGKKNQKTLPVNMKILIHFHSEFILNQDGQFALILEERPHVNGVV
                     NGASFNYARANNKREWERTRLV"
     gene            5273..5785
                     /locus_tag="AC1PIV_001556"
     CDS             5273..5785
                     /locus_tag="AC1PIV_001556"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HIP6612569.1"
                     /translation="MNLKDYIATIPNYPKEGIEFRDISPLMADGNAYSYAVREIVQYA
                     TDKQIDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGIVAGCAFLIELDDLKGREAIG
                     DYDYKVLMHY"
     gene            5889..6830
                     /gene="metA"
                     /locus_tag="AC1PIV_001557"
     CDS             5889..6830
                     /gene="metA"
                     /locus_tag="AC1PIV_001557"
                     /EC_number="2.3.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004414 - homoserine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-acetyltransferase MetA"
                     /protein_id="HIP6612570.1"
                     /translation="MPIKIEKSLPAVEILRKENIFVMDSDRASHQDIRPIKILILNLM
                     PQKIVTETQLLRLLANTPLQLEVEFLYMASHESKNTHSGHLKQFYKTFEQVRDSYFDG
                     LIVTGAPVENLPFEEVDYWHELTQVFDWSKTHVYSTLHICWGAQAGLYARYGVPKHSM
                     SRKLSGVYCQEVTNPTSPLMRGFDDEFRSPHSRYTEVREADIAHLSGLTILSQGPEVG
                     LSILASKDLRGIYSFGHLEYDRDTLAKEYQRDCIAGKNPHLPENYFKGDDPTSKPSLS
                     WNLPAAQFFTNWVNYAVYQETPYDWHIFEQSAQSASL"
     gene            6840..7514
                     /locus_tag="AC1PIV_001558"
     CDS             6840..7514
                     /locus_tag="AC1PIV_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002941367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HIP6612571.1"
                     /translation="MNYSQQFRQGHLVLPAAILFHYQELFPSADDFLIWQFFLYQNSS
                     AIESLAPSEIAQATGKTVAQVNQAIENLQDAGLLEFKTISIAGEIEMIFDALPAFEKL
                     DVLLTPKQAVEIVQPENDLKTLVGDFERELGRFLSPFEIEDLQKTIEDDKTSIDLVRA
                     ALKEAVFNNKTNWKYIQAILRNWRREGITTVVQVEAKNAEREIQTPKNVTVSSDFLDA
                     MDLWKD"
     gene            7516..8199
                     /locus_tag="AC1PIV_001559"
     CDS             7516..8199
                     /locus_tag="AC1PIV_001559"
                     /EC_number="2.1.1.217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002941360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0160105 - tRNA
                     (adenine(22)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine(22)-N(1))-methyltransferase"
                     /protein_id="HIP6612572.1"
                     /translation="METKLSKRLETVASFVPQGARLVDVGSDHAYLPLFLVEQGRIDF
                     AIAGEVVQGPYQSALQNVEQAGQTEKILVRLANGLGAFEKSDQMTAVTIAGMGGRLIA
                     EILEAGKEKLATIERLILQPNNREDDVRRWLEKNGFRLVAEKILEENGKLYEVLVAES
                     GQMRLSEVERRFGPYLLEETSPVFVKKWRRELEKLSFALEQVPSERQGDRFAISQKIQ
                     QIQEVVHVS"
     gene            8189..8983
                     /locus_tag="AC1PIV_001560"
     CDS             8189..8983
                     /locus_tag="AC1PIV_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051540 - metal cluster binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HIP6612573.1"
                     /translation="MLASQVIERYQAFCPHSLAMEGDVKGLQIGTLNKEIQRVMVALD
                     IRETTVAEAIDKKVDLIIVKHAPIFRPINDLVADNPQTKMYLDLIKHDIAVYVSHTDI
                     DVVEGGLNDWFCELLEIQDTTYLIETAEGQGLGRVGTIAEQTLEELALKVKSVFDLDA
                     VRLVTYGHQAKQYVSRVAICGGSGGSYYHEALAKGADVYITGDIYYHTGQDMLTQGLL
                     AIDPGHHIEVLFIKKIAELLEIWKAKEGWDVEILPSTVSTNPFRHL"
BASE COUNT         2718 a         1636 c         2065 g         2653 t
ORIGIN      
        1 taatgaacta aaatctgtta taatggtaaa aaactaaggg agagatgtat ggaaaaactt
       61 tggaaaatta tatatagtcg gacatttatt gtcattagtt tgattattct aaccattttc
      121 cttattcttt ggttggtagg ttcggcagca acctatatgc ctgctttatt gattgttttg
      181 caaatttttt cgatttttgt agctatttca atcatcaata gaccgatgaa taccagtttt
      241 aagttaacct ggattatttt tgtcattggt attccgattt ttggtgccct attctatttt
      301 attttgcagt ccaacattga aaccaaacgt tatcgtaaaa attttcataa gcaagcacaa
      361 agacttcggg agtatagtaa gacgtctgaa aaggtcatga aggcgttgga gcaggaagat
      421 aaggagcaac tgaaattagc tcacttcatg agtgagtacg ttggctaccc aattcatacc
      481 aatacggatg ccgtctattt ttcaacaggt caggaaaaat ttgaagctct actagaagaa
      541 ttgaaaaagg cagagcagta tattttcatg gagtacttta ttgttgatat gggatatatg
      601 tgggattcta tccttgacat tttgaaggaa aaggcagcgc aaggggtgga agttcgtttt
      661 atgtatgatg ggatgaattc actgaccaat cttccctata attactataa aaccttgaga
      721 aaatatggaa taaaagccaa agtattttct caaattatcc cagccttatc tacggtgcaa
      781 aataaccgtg accatagaaa aattgcgatt attgatggaa aggttgcctt taccggcggc
      841 attaatatcg cagatgaata catcaacaag aaagtgcgtt ttggttactg gaaagacgca
      901 gcgattatga ttaggggaga agctgttgca aactttacgt tgatgttcct tcaaatgtgg
      961 aattacaatg aaaagacaga gacagatgac ctaaaatacc tcaaaacgca taaagattta
     1021 gagacggaaa ccgttgatgc cgaaggtttc ttccttccgt atggcgagaa tccatttgat
     1081 ggagatgagg tagccaaacg agtctgccta gacatgattc agtcggcaac ggattatatt
     1141 tatatcatga caccctacct agtgttggat gatgaaatga ttgataattt gacttatgct
     1201 gcgaagcgtg gagtcgaggt tcgcattctg ctaccgcata tctacgataa aaaatctgcc
     1261 tatttggctg ctcgtactga ttttccgact tacttggaag caggaattga aatctttgaa
     1321 ttccagcctg gatttgtcca ttccaaagtt gttttggtcg atgataagaa agctactgtt
     1381 ggtacggtga atatggattt tcgctctttt tatcttaatt ttgaatgcgg tctctatatt
     1441 tacaatcact cggaagtttt ggcagctatt aaggatgact ttactcattc cttcaaaaaa
     1501 tcacagcaaa ttaaccttct aaccttccat aaaacgtact cttggtataa gcgtttggga
     1561 ggagccctac tgcgaattat ttcgccgtta ttataaattg taatattcgt tcttcatgga
     1621 gcaagggatc gacattctgt ttcggtctta ccttgctcca tttttcttgg aaaatgatat
     1681 aatagaaaga tagtttatac tcggaaaatt tacaggctac ttgtgatttt gagtattaag
     1741 gagtaaaaaa cgtgataaag cccaattatg actggcaatt attgaccggt ttttctgatg
     1801 aacaatttat caaaattgct aaaaaagaag gagtggaccc ggtagcggct aagttgctgt
     1861 atgaacgtgg catccattcg gcggaagaat tgcatacttt cttacaacca agcttagaag
     1921 accttcacga tccctattta ctacatgata tggacaaggc ggtagagcgg attcgccgag
     1981 caatcgaaaa ttacgaacac attttgattt atggagatta tgacgcagac ggtatgacct
     2041 cggcatctat tctgaaagaa actctggagg aaatgggggc agaagtccaa gtttatcttc
     2101 ccaaccgttt tacagatggc tatgggccga atcagtcagt ttacaagtat tttatcgagc
     2161 aacaggggat ttctcttatt gtgacggtgg acaatggcgt agcgggtcat gaagcgattg
     2221 cctatgccca ggaaatgggt gtcgatgttg tcgtgacaga ccaccattcc atgcaagaaa
     2281 cccttcccaa tgcctatgcg attgtacatc cagagcatcc agaaggaaat tatcccttca
     2341 aacatttggc gggctgcggc gtggctttta aattggcctg tgctcttctt gaaactgttc
     2401 atgcagactt gctggatttg gtcgcaattg gcaccatcgc tgatatggtt agcttgaccg
     2461 atgagaatcg tgtcatggtc aaatatggtc tctcgcttct caaacagact gagcgagcag
     2521 gtttgcaaga gttgataaag atagctggta ttgacataga cagtattgat gaagaaacag
     2581 ttggtttcca acttgctccg aggttgaatg cccttggtcg actcgatgat ccaaatccag
     2641 ccatcgaatt actgactggt tttgatgacg aagaggccca tcaaattgcc ctcatgattg
     2701 acagtaaaaa tgtagaacgt aaagacgtcg tccaagcaat ttacgatgaa gcaaaaacca
     2761 tgctccgtca tgatagacct gttcaagttc tggctaaaga aggttggaac ccaggtgttt
     2821 tagggattgt agcaggacgc ctactagaag aactgcagca acctgttatc gtcttgtcta
     2881 ttgaagatgg taaggcaaag ggttcggctc gttctgttga agcagttgac attttcaagg
     2941 cacttaaaga tcatcaggac ctatttatcg cctttggtgg tcatgctggt gcagcaggta
     3001 tgaccttgga agttgacaaa cttgaagagc ttgctctgac cttgacagac tacattatcg
     3061 aaaataaatt ggatttatcc agcaagtctt cgctggtctt agatgaagaa ttggatttag
     3121 aggaattaac cctagatact ctaaaatctt tcgagaagct tgcgccttac ggcatggata
     3181 ataaaaagcc tgtattttac atcagagact ttcaggtgga atcagcaaga accatggggc
     3241 agaataatgc ccatttgaaa ctacgcatta ctaaaggtgc tgctggattt gatgttcttg
     3301 cttttggtaa gggcaatcta gccttggaat tttcacaggc caagggctta gaactagctg
     3361 tcaccttgtc tgtcaatcaa tggaatggca ataccagtct tcagctcatg ttggttgatg
     3421 ctcgggtcaa tggtgttcaa ctttataata ttcgtggaaa acaacatcct attcctgcag
     3481 gggtcccaat tttggacatt gaaaatccag tagcagataa caaagcaatt gtcttggcta
     3541 acttgcctga ggacctcagt agtctgcgta gctattttca ggaaagagaa tttgaagcca
     3601 tttattttaa aaacgaaatt gccaaaccgt actatctaga tggttatggt agccgagaac
     3661 aattcgctaa attgtataag actatttacc aatttgaaga gtttgatgtt cgctataaac
     3721 tgaaagattt ggctgtttac ttaaaaatta aggacagtct attggttaaa atgattcaga
     3781 ttttccaaga attagaattt gtcacgattg cggatggggt catgcgggtc aacaaagagg
     3841 cacagaagcg agagatttca gaaagtcaaa tatatcaaga attgaaagaa acagttatcc
     3901 aacaagagtt gatggcgctt ggcaccgttc aggaaattta tgaatggcta tgtggtcgcg
     3961 tttgatgaca gtagaagctc tggttgttgg agtgattgga acgcttctct acacttattg
     4021 gtttatcagg caaaaaggtt tgttgaaaaa tcttgaacag ataaccgaaa taaagcacgc
     4081 actgattgaa ttacggcgag taggatggtc agaaagagcc atcaaaaagg tttttctgaa
     4141 acaactgttg cctctaaaac aagaagacat cccagcattt gttcaaaatt tcataaaaga
     4201 agctactatt tttgcctcaa ctagctttta tcagttgata agagttgaca gtcgctcttt
     4261 aagccaagag aaagcgacgg ccttattgga gcaatgtatg aatatgttag attttcctga
     4321 ggaattaagt catgggatat tacctgaact tttgcagaag atggatgtga attgtcctcc
     4381 acaccatccg ttttggcggt actttgctaa gctagttgat aaggcttttc cagttcggga
     4441 attagaagtc aaacggccgt taaacagaca ggtccatcag ctacgctacc ttatttccta
     4501 tcagcagact ttttgggtgc gtcagcagtt tggaaaagga aaaacagatt ggcaggctct
     4561 gatagcctat gtacgtagcc tacctcggtg gtcttatcgc ttacgagaat ctgcccgcct
     4621 acacaataaa caactgttcg gcaagaaaaa tcagaagacc ttgccagtca atatgaagat
     4681 tttgattcat tttcacagcg aatttatcct aaatcaagat ggacaatttg ccttgatttt
     4741 agaagaacga ccgcatgtca atggcgtggt aaatggggct tcctttaatt atgccagagc
     4801 taataataag cgggagtggg aaagaactcg actggtctaa aaagagttcg tcttcccacc
     4861 cccgcacagt tgattaggtt ggatttggag tgtaaaacac gaacaaatcc gccaatcaac
     4921 cactgcactg agatgttgac acgaactcta agaagtggcg ctgagctttt tgccctgcct
     4981 ctccagttgg caggcaggat cccatttttc ggaaagaatt gctacgctca aagatgggag
     5041 tctatttatc tcctactcgc tttcgtcgct accaaaaagg aagaaatgag gttggctggg
     5101 agcagtctta ctttaatcag caaggaagct tttcctatgg tggacatagt agagcagctt
     5161 gtgtggcgaa tttgaggaga cgatttgcta aagatatatg tctgaaatgt accaaaaaac
     5221 aatttcatgg tataatgaag agtaaaaatt atttttaaaa agagagagac aaatgaactt
     5281 aaaagattac atcgcaacaa ttcctaacta tccaaaagaa ggtatcgaat tccgtgacat
     5341 tagccctttg atggcagatg gaaatgctta tagctatgca gtacgtgaaa tcgttcagta
     5401 tgcgacagat aagcaaatcg atatgattgt tgggccggag gcgcgtggtt tcatcgttgg
     5461 atgtccagtt gcctttgaat tgggaatcgg ttttgcacca gttcgtaagc caggtaagtt
     5521 accacgtgag gttatctcag ctgattatga aaaagaatat ggtgtagata cattgacgat
     5581 gcatgcagac gcaatcaaac caggacaacg tgtcttgatt gtcgatgact tgttggcgac
     5641 tggtggtact gtaaaagcaa cgatcgaaat gattgaaaag cttggcggta tcgttgctgg
     5701 ctgtgccttc ttgattgagc tagatgattt gaaaggccgc gaagcaatcg gtgattacga
     5761 ctacaaggtt ttgatgcact attaatctaa ggttatagcc aaaacttata actggtccta
     5821 tttttattct aattgaattg catagcaacc tgtcttataa taaatataag aaaattggga
     5881 ggttgcttat gccaattaaa attgaaaaat cattaccagc agttgaaatt ttgagaaaag
     5941 agaatatttt tgtgatggat agtgaccgag ccagtcatca ggacattcgt cctatcaaaa
     6001 tccttattct caatctcatg ccacagaaga tagtgacgga gactcagttg ctccgtcttt
     6061 tggctaacac tcctttacag ctagaggttg aatttctcta catggctagt cacgagtcca
     6121 aaaatacaca ctcgggccat ttgaagcagt tttataagac ttttgagcag gtcagggata
     6181 gctattttga tgggctcatc gtgacaggag caccagttga aaatttacct tttgaggaag
     6241 ttgattactg gcatgaactt actcaagttt ttgattggtc aaaaacacat gtttattcaa
     6301 cattgcacat ttgttggggt gcacaggcag gtttgtatgc acgctatggt gtacccaaac
     6361 acagtatgtc tcgaaaacta tcaggggtat attgtcaaga agtgactaat ccaacgagcc
     6421 ctcttatgcg tggatttgac gatgaatttc gttcaccaca ttcccgttat acggaagtaa
     6481 gagaagcaga tattgcccat ctgagtgggt tgacgatttt atcacaaggt ccagaagttg
     6541 gcctatccat tctagccagc aaggatttaa gaggaattta tagttttgga catttagagt
     6601 atgataggga tacactagct aaggaatacc aacgtgattg tatagctgga aaaaatcccc
     6661 atttaccgga aaattatttc aaaggagatg accctacaag caaaccatct ctctcttgga
     6721 atttaccagc agcacaattc tttaccaact gggtgaatta tgctgtctat caagaaactc
     6781 catacgactg gcatatcttt gaacaatcag cccagtcagc tagtctttaa agaggaagta
     6841 tgaactattc acagcaattt cgtcagggac atttggtcct gccagcagca atattattcc
     6901 actatcaaga gctttttccg tcggcagatg attttttgat ttggcagttt ttcttatatc
     6961 aaaattcttc agctatcgaa tcattagcgc ctagtgagat tgctcaagct actggtaaaa
     7021 cagttgctca ggtcaatcaa gctattgaaa atctccaaga tgctggactc ttagaattta
     7081 agacaatcag tattgctggt gaaattgaaa tgatattcga tgcgcttcct gcttttgaaa
     7141 aattggatgt tctgttaact ccaaaacagg cagttgagat tgtgcaacca gagaatgatt
     7201 tgaagacctt ggtgggtgat tttgaacgtg aattgggccg ctttttatcg ccgtttgaaa
     7261 ttgaagattt gcagaagact attgaggatg acaaaacttc gattgatttg gttcgtgcag
     7321 ccttgaaaga agctgttttt aacaacaaaa caaattggaa atacatccaa gctattctac
     7381 gaaactggcg ccgtgaggga attactacag ttgtgcaagt agaagcgaaa aatgcagaaa
     7441 gagaaatcca gactcctaag aatgtgactg tttcaagtga ctttcttgat gcaatggatc
     7501 tctggaaaga ttgatatgga aacaaaatta tctaaaaggc tggaaacagt cgcaagtttt
     7561 gtcccacaag gggcacgtct agttgatgta gggagtgacc atgcttatct ccctcttttt
     7621 ttggtagagc aggggcgtat tgattttgcc attgcggggg aagtcgttca aggtccctat
     7681 cagtcagcgc tccagaatgt agagcaggcg ggacaaacag agaaaattct agtccgtttg
     7741 gcaaatggct taggcgcgtt tgagaagtct gaccagatga ctgccgtgac catagcaggt
     7801 atggggggac gcttgattgc ggaaatctta gaagcaggaa aagaaaagct tgcgaccatt
     7861 gaacgtttga tactccagcc aaataatcgt gaagatgatg tgcgtcgatg gttggaaaaa
     7921 aatggtttta gattggttgc tgaaaagatt ctggaagaaa atggcaagtt atatgaagtc
     7981 ctcgttgcag aatcaggaca gatgagattg tcagaagttg aacgtcgttt tggtccctat
     8041 ctactagagg agacctcgcc agttttcgtc aaaaagtgga gaagagaact tgaaaaatta
     8101 agttttgctt tggaacaagt tccatctgaa cgccaaggtg accgctttgc catttcccaa
     8161 aagatccaac aaattcagga ggtagtccat gttagctagt caggttattg agcgctatca
     8221 agccttttgt ccccattctt tggctatgga aggcgatgtc aaagggctgc aaatcggtac
     8281 ccttaataaa gagattcaac gtgtcatggt ggctctggat attcgtgaga caacagtggc
     8341 agaggcgatt gataaaaagg tagatttgat tatagtcaag cacgctccga tttttcgtcc
     8401 aataaatgat ttggtggctg acaatccgca aactaaaatg tatcttgatt tgattaagca
     8461 tgatattgca gtctatgtta gtcatacaga tattgatgtg gttgagggtg gtctcaacga
     8521 ctggttctgt gaactactag aaattcaaga tactacctac ttgattgaaa ctgccgaggg
     8581 gcaggggctt ggccgtgtgg ggacaatagc agagcagact ttggaagaat tggctttgaa
     8641 agtcaagtct gtctttgatc tagatgctgt ccgtctagtg acctatgggc accaagccaa
     8701 gcagtatgtc agccgtgtag ccatctgtgg aggcagtggt gggtcttact accatgaggc
     8761 tcttgctaag ggggcagatg tttacatcac gggcgatatt tactaccata ctgggcagga
     8821 catgctgact cagggcttgc tggctattga tccaggccat catatcgaag tattatttat
     8881 caaaaaaatt gctgaattgt tggaaatatg gaaggcaaaa gaaggttggg atgtcgaaat
     8941 tctaccttca actgtttcaa ccaatccgtt tagacatttg tgataaatta atcagcactt
     9001 gattgtggaa agaccaagac gacatttaat gtagttttag gtcttttatt ttttagatat
     9061 tttcttattt at
//
LOCUS       DBNFCO010000069         9037 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.069, whole genome shotgun sequence.
ACCESSION   DBNFCO010000069 DBNFCO010000000
VERSION     DBNFCO010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9037)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9037)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9037
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.069"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            3..75
                     /locus_tag="AC1PIV_001561"
     tRNA            3..75
                     /locus_tag="AC1PIV_001561"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:36..38,aa:Asn,seq:gtt)
     gene            98..169
                     /locus_tag="AC1PIV_001562"
     tRNA            98..169
                     /locus_tag="AC1PIV_001562"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:131..133,aa:Glu,seq:ttc)
     gene            288..2306
                     /gene="recG"
                     /locus_tag="AC1PIV_001563"
     CDS             288..2306
                     /gene="recG"
                     /locus_tag="AC1PIV_001563"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HIP6612574.1"
                     /translation="MKRLCDELSVLPGIGPKSAEKFLKISIQNINDLLTYYPFRYEDF
                     ESKSIYDLQDGEKAVVVGEVVSPANVQYYGYKRNRLRFSMKQGEVVLAVSFFNQPYLA
                     DKIVLGQDIAVWGKWDKAKASLTGMKILAQVSDELQPVYHVAQGISQVNLVKAIKTAI
                     DQGYLHLLEENLPSVLRERYRLMNRREAVFAMHFPTNLEEYRQALRRMKFEELFYFQL
                     QLQMLKANNRDILNGLKIAYDADRLAMQIRQLPFVLTDAQSGALAEILSDMKSYGHMN
                     RLLQGDVGSGKTVVAGLAMFAAVTAGMQAAIMVPTEILAEQHFESLRQLFPELSIALL
                     TGGMKAAERRTALEAISSGQVDIIVGTHALIQESVTYHKLGLVVTDEQHRFGVKQRRL
                     FREKGDNPDVLMMTATPIPRTLAITAFGDMDVSIINQLPAGRKPIITRWVKHQQLPTV
                     LDWLERELEVGAQVYFISPLIEESEALDLKNAVDLQSDLQAHFGEQVTVDLLHGKMKN
                     DEKDAIMQAFKERKTNILVSTTVIEVGVNVPNATVMVIMDADRFGLSQLHQLRGRVGR
                     GHKQSYAVLVANPKTESGKERMKIMTETTDGFILAEADLKMRGSGEIFGTRQSGLPEF
                     QVANIIEDYPILEEARRVASQIVSVENWQEDPNWSILLANLKDREELD"
     gene            complement(2370..3329)
                     /locus_tag="AC1PIV_001564"
     CDS             complement(2370..3329)
                     /locus_tag="AC1PIV_001564"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004067 - asparaginase activity [Evidence
                     IEA];
                     GO_process: GO:0006528 - asparagine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HIP6612575.1"
                     /translation="MKKILVLHTGGTISMQTNHQGEVAANKTNPMTQIDSPLEETQVT
                     SLDFLNVPSPHIRLEHMMTLYQKIKEEQMNFDGFVITHGTDTLEETAYFLDTMAIPEK
                     PIVLTGAMRSSNELGSDGIYNYRTALRVATDDKSADKGVLVVMNDEIHAAKYVTKTYT
                     TNVSTFQTPTHGPLGLVTKREILYFKTAEPRVRFDLSTVTGTVPIIKAYADMDSILLD
                     SLTASSISGLVIEALGAGNLPPTILPAIKKLLDQKIPIILVSRCFNGIAEPVYAYQGG
                     GIQLEKDGILFVKELNAQKARLKLLIALNAGLEEQSLADYIQG"
     gene            3399..4764
                     /locus_tag="AC1PIV_001565"
                     /pseudo
     CDS             3399..4764
                     /locus_tag="AC1PIV_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002891795.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
     gene            complement(4780..5232)
                     /locus_tag="AC1PIV_001566"
     CDS             complement(4780..5232)
                     /locus_tag="AC1PIV_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015445117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0050896 - response to stimulus [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HIP6612576.1"
                     /translation="MTQSYKTILVAVDGSKGAELALHKAIHVALRNQARLIIAHVIDT
                     RALHNVVAFDASVYESLEREAELLLEEYKQEALNAGLTDVQIRIEFGNPKTLLAIDIP
                     KETGADLMLLGATGLNAFERLLIGSSSEYIMRHATIDLLIVRDGEKSL"
     gene            5387..6601
                     /locus_tag="AC1PIV_001567"
     CDS             5387..6601
                     /locus_tag="AC1PIV_001567"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HIP6612577.1"
                     /translation="MKQFNKSTKLDDVAYDIRGPVLEEAMRMRANGEQILRLNTGNPA
                     EFGFTAPDEVIRDLIHNARKSEGYSNSKGIFSARKAIMQYCQLKKFPNVDIEDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGKAVHYVCDEVAEWYPDLAD
                     MESKVTSRTKAIVLINPNNPTGALYPKEILKGIIDIARRHELIIFSDEIYDRMVFDGA
                     VHIPIATLAPDLFVVTMNGLSKSHRICGFRVGWMVLSGPKKHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGYQSVDELLMPGGRLYEQREFITKAINDIPGLSAVKPKAGLYV
                     FPKIDREMYRVEDDEQFVLDFLKQEKVLLVHGRGFNWKDPDHFRIVYLPRVDELAEIQ
                     EKMSRFLRQYRR"
     gene            7010..7798
                     /gene="codY"
                     /locus_tag="AC1PIV_001568"
     CDS             7010..7798
                     /gene="codY"
                     /locus_tag="AC1PIV_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HIP6612578.1"
                     /translation="MTTLLEKTRNITSILKRSEEQLAEELPYNAIAEHLSAIIDCNSC
                     IINSEGEVLGYHMSYETNNDRVEEFFQNKQFPEGYVKAVAQVYDTQVNLPVESELTAI
                     PVESRSTYPNGLTTIAPIHVTGIRFGSLIIWRNDEQFHDDDLILVEIAATVVGIQLLN
                     FQREEDEKNIRRRAAVNMAVNTLSYSEMKAVAAILGELDGNEGQLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLIPAIFDEIKKRDY"
     gene            7811..8341
                     /locus_tag="AC1PIV_001569"
     CDS             7811..8341
                     /locus_tag="AC1PIV_001569"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003039591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HIP6612579.1"
                     /translation="MDYIVDFVADEGKLTAGKSAQAISKRIAQVTQEAFENGDYIFFA
                     IDGHEEGDEFHPEAQLFPSHNIIGTQGRDLYGPLADFYQKHKGHARVRWMDKRHYSTF
                     SGTDLDVRLRERGVDTVVLTGVLSDICVLHTAIDAYNKGYRIEVVSSAIAALTEENHQ
                     FALNHLRHVLGATIID"
     gene            8595..8942
                     /gene="rplS"
                     /locus_tag="AC1PIV_001570"
     CDS             8595..8942
                     /gene="rplS"
                     /locus_tag="AC1PIV_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HIP6612580.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVISRKGQGISEMYTVRKISGGVGVERTFPIHTPRVDKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
BASE COUNT         2534 a         1456 c         2190 g         2857 t
ORIGIN      
        1 attccgccat agctcagttg gtagagcgca tgactgttaa tcatgatgtc acaggttcga
       61 gccctgttgg cggagtaaag agaaatcttt agtatatggt ccgttggtca aggggttaag
      121 acaccgcctt ttcacggcgg taacacgggt tcgaatcccg tacggactat atttggagac
      181 tgcttaagtc tctttttttt gttttttgag gtgtatgggc tttaatatgg ctcctttttc
      241 ttttcttgtt actttgtcta ttcattgttt gttgatataa tagagatatg aaaagactat
      301 gtgatgaatt atcggttttg ccagggattg gtccaaaatc ggctgaaaaa ttcttaaaaa
      361 ttagcattca gaatattaat gatttgctga cttactatcc atttagatat gaagattttg
      421 agagtaagtc tatttatgat ttgcaggatg gggagaaggc agtggtagtt ggggaggtgg
      481 tatctccagc taatgtacag tattatggtt acaaaagaaa tagactccgt ttttcaatga
      541 aacagggtga ggttgtctta gcagtttcgt tttttaatca gccttattta gcagataaga
      601 ttgttttggg gcaggatatt gcagtttggg gaaagtggga taaggctaag gcaagtttga
      661 caggaatgaa aattttggct caagtatcag atgagctcca acctgtctat catgtggcgc
      721 aagggatttc gcaagtaaat ttggttaagg ctattaaaac agctattgat cagggatatt
      781 tgcatttatt agaggagaac ttgccatcag ttttacgaga gcgctatcgg ttaatgaatc
      841 gccgagaggc ggtttttgcg atgcattttc ctacaaattt agaagagtat agacaagctt
      901 tgcgacgtat gaagtttgag gaattatttt attttcaatt acagttgcaa atgctgaaag
      961 ccaacaatcg tgatattttg aatggtttga agattgccta tgatgctgat agattggcta
     1021 tgcaaataag acaattgccg tttgtcttaa cagatgctca gtctggggct ttggctgaaa
     1081 tactatcaga tatgaagtcc tatgggcaca tgaatcgttt gttacaaggg gatgttggtt
     1141 cagggaagac agtagttgct ggattggcta tgtttgctgc tgtgactgcg gggatgcagg
     1201 ctgcaattat ggtgccgaca gaaattttgg ctgagcaaca ctttgagagt ttgcgccagc
     1261 tttttccaga actttctatt gctcttttga caggtggaat gaaagctgcg gagcgtcgta
     1321 ctgctttaga ggcgatttct agtggtcagg tagacatcat tgtaggaact catgctctta
     1381 tacaggaaag tgtgacgtac cataagcttg gtttggttgt gacggatgag caacatcgtt
     1441 ttggtgttaa acagcgccgt ctgtttcgtg agaagggtga taatccggat gtgcttatga
     1501 tgactgctac acctattcct cggacgttag ccattacagc ttttggagat atggatgtat
     1561 caattattaa tcagttacct gctggtcgaa agccaattat cactcgctgg gtcaaacatc
     1621 aacagctgcc cacggtctta gattggttgg agcgggagtt agaagtgggt gctcaggttt
     1681 attttatctc tccgctgatt gaagaatctg aggctctaga tttaaagaat gctgtagatc
     1741 tacaatctga tttacaggcg cattttggag agcaagttac agtggatttg ttacacggta
     1801 agatgaagaa tgacgagaaa gatgccatca tgcaggcttt taaggagcga aaaacgaata
     1861 ttttggtttc taccactgtt attgaagtcg gagtcaatgt gcccaatgca acggtgatgg
     1921 ttattatgga tgctgatcgt tttggtttaa gccaattaca tcagttgaga gggcgtgtag
     1981 gacgtggtca taagcagtct tatgcagtgt tagttgctaa tcctaaaaca gagtctggta
     2041 aggaacgcat gaaaattatg acagagacga cagatggttt tattttggct gaagctgact
     2101 taaaaatgcg tgggtctgga gaaatatttg gaactcgtca atcaggtttg ccagaatttc
     2161 aagttgcaaa tattatcgag gactatccaa ttttagagga agcaaggcga gttgctagtc
     2221 agattgttag cgtggaaaat tggcaggagg accctaattg gtcgattttg cttgctaatt
     2281 tgaaagatcg agaggaattg gactagtcat ataaaaaagg ccaacacaca tgtgttggtc
     2341 ttttgacata ttgtatagtt cgtcagcgat taaccttgga tgtaatctgc caagctttgc
     2401 tcttccaagc ctgcattgag agcgataagg agtttgagtc gggctttttg agcattcaat
     2461 tctttaacaa atagaatgcc gtctttctcc agttggatgc cacctccttg gtaggcatag
     2521 acaggctcag caattccgtt aaaacagcga gataccagaa taatgggtat cttttgatca
     2581 aggagtttct taatggctgg aaggatggta ggcggaagat ttccggcgcc gagtgcttca
     2641 ataactaaac cggaaattga gcttgcagtg agtgaatcaa ggagaatgga gtccatatct
     2701 gcataagctt ttatgattgg gaccgttcct gtgactgttg ataagtcaaa tcgaacacgt
     2761 ggttcagcag ttttaaaata gagaatctct cgtttggtga ctaatcccag tggtccatgg
     2821 gttggtgttt gaaaggttga gacattggtg gtatacgttt ttgtaacata tttagcagca
     2881 tgaatttcat cgttcatgac cactagaaca cctttatctg cggatttatc atcagtagcc
     2941 acacgtaggg ctgttcggta gttataaatc ccgtcgctac ccagttcatt tgaggaacgc
     3001 atggctccgg tcaatacaat tggtttttct ggaatagcca ttgtatcaag gaaataggca
     3061 gtctcttcta aagtatctgt gccatgtgta atgacaaaac catcgaagtt catttgttct
     3121 tctttgattt tttggtatag agtcatcatg tgttctaagc gaatgtgtgg acttggaaca
     3181 ttgagaaaat ccaaggatgt cacttgagtt tcttctagtg ggctatcaat ttgggtcatt
     3241 ggattggttt tattcgctgc aacttcaccc tgatgattgg tttgcataga aatggttcca
     3301 cctgtatgca gtactagaat ttttttcata aattttcagt ttctttcaaa gtgtgatata
     3361 ctaattgtaa cataattctt agaaagtagg tgagttggtt gacgataaag gctgtatttt
     3421 tcgatattga tggtacctta ttgaccgaca atcgtatggt tagtagttca actattctcg
     3481 ccattaatgc tttgaaagag aaggggattt tagttggtct agctacagga cgtgatcctc
     3541 gttttgtttt gcagtatatg gctagtttag ggctagattt ggccattgct tataatggtc
     3601 aatatatttt ttcaagagaa gaagttattt atagtcagag tttagagcca aagcaaattg
     3661 aacaaattat ggagtatgcg caaactcacc ataaggattt atcttttgga actgctaaag
     3721 gcatatttgg tagtaagatt atgagtgctg gaacaggaaa ttttgcatat cgtgtgacgc
     3781 gtatgattcc ggagtcctgg gctggaatca taaattttat tttcaatcgt ttggtacgtt
     3841 ggattagtcc tcaacaggaa acgaatttga aaggttttct ctttcaacca atctatcagc
     3901 tgatgttgct gacgacggaa agggagacac aatcattgga ggtgctcttt ccgaacttgt
     3961 cttttacgcg ttcgagtccc tatgcgactg atattatcag taagggaaat tcaaaattat
     4021 cgggtattgt aaaggttgca gatcgatatg gttttgagtt agatgaagtt atggtattcg
     4081 gggattctaa taatgatttt gaaatgttga atgaaattca gcactcggta gcgatgggaa
     4141 atgggacgaa aaaggttaaa cacgcagctt cctttgttac ggatacaaat aatcgtgatg
     4201 ggatttataa ggcattaatt cattttggtg tgattgaggg ataagatgtt tcagagcaag
     4261 gacgataatt ttaatagggt aaaggatttt cattttttaa tggatggtga aacacaagaa
     4321 cttcccagtg tgtatgatgg acagacggct ttgtatcgcg ctggttttaa attggaggag
     4381 ttggtagaat ttctacatgc agcttcagaa tctgaagttg agtttcatga ttttattcaa
     4441 caacttcatc aggatttaga tactgctgct gctaaggtat ctggcaagag aggtttcggg
     4501 gtttcgatgc aggatcaggt agatgctttg ctggatattc tttattttac atatggttcg
     4561 tttgttttga tgggggttga tccagaacca atttttcaga tagtccatac tgcaaatatg
     4621 gggaaaacat ttccagatgg gaaggcccat tttgatccaa ttacccataa aattttaaaa
     4681 cctgatgatt gggaagaacg gtttgctccg gaggaaaaga ttcaggaaga gctgaaaaga
     4741 cagatgaaaa gacttgattc gtaaatcaag tcttttggtt tataaacttt tttctccatc
     4801 gcgaacaatg agtaaatcga tagttgcgtg gcgcatgata tattcggatg aggatccgat
     4861 taggagacgt tcaaaggcgt ttagaccagt tgctccaagt aacataagat ccgcaccggt
     4921 ttcctttgga atatcgatag ccagtagggt tttagggtta ccgaattcaa tgcgaatctg
     4981 tacatcggtc agaccggcgt tgagagcttc ttgtttgtat tcttcgagga ggagctccgc
     5041 ctctctttct aaagattcat agacagaggc gtcaaatgca acaacattgt ggagagcacg
     5101 ggtgtcaatc acatgggcga taatcagacg tgcttggttg cgtagtgcaa catgaatggc
     5161 tttatgaaga gctaattctg ctcctttaga gccgtctaca gcgacgagta ttgttttgta
     5221 agattgtgtc ataatagtca ctcctttcag aagagctttg tcccgaaata ggtagagtag
     5281 ttccttacat ttttattata agccttttga gagaaaatgt aaaggattct tgtacttttt
     5341 tagcttttac agtacaatag aaaagataga aagttgaggt gacgacatga agcaatttaa
     5401 caagtcaaca aaattggatg atgtagcata tgatattcgt gggcctgttt tggaagaggc
     5461 catgcgcatg cgtgccaatg gagagcagat tttacgtttg aatacgggga atcctgcaga
     5521 atttggtttt actgctccag atgaagttat tcgtgacttg attcataacg cccgtaaatc
     5581 agagggatat tcgaacagta agggaatttt ttctgcacgt aaggctatca tgcagtattg
     5641 tcagctaaag aaatttccaa atgttgacat tgaagatatt tatcttggaa acggcgtgag
     5701 tgagctgatt gttatgtcta tgcaaggttt gctagataat ggtgatgagg tgttggtgcc
     5761 aatgccagac tatcctctct ggactgctgc agttagtttg gctggtggta aagctgttca
     5821 ctatgtttgt gatgaagtag ctgaatggta tccagatttg gcagatatgg agtccaaggt
     5881 gacttctcga accaaggcaa ttgtccttat caatccaaat aatccaactg gtgctctcta
     5941 tccgaaagaa attttaaaag gaatcattga tattgctcgt agacatgaat tgatcatttt
     6001 ctctgatgag atttatgatc gtatggtctt tgatggagct gttcatatcc ctattgcgac
     6061 actggctcca gatttatttg ttgtgacgat gaatggactg tctaaatcac atcgtatttg
     6121 tggtttccga gtaggttgga tggtcttatc tggtccgaaa aagcatgtaa aaggttacat
     6181 tgaaggcttg aatatgttgt ccaatatgcg tttgtgttca aacgttttgg ctcaacaggt
     6241 tgttcaaact tctttgggag gttaccaatc ggttgatgag ctcttgatgc ctggcggacg
     6301 cttatatgaa caaagggagt tcattaccaa ggcgattaat gatattccgg gactttctgc
     6361 tgtaaaacct aaggctggtc tgtatgtatt cccaaaaatt gatcgtgaga tgtacagagt
     6421 tgaggatgat gaacaatttg tattggattt cctcaagcaa gaaaaagtac ttttggtcca
     6481 tggtcgaggt tttaactgga aggatccaga tcatttccgt attgtgtatt taccacgtgt
     6541 tgatgagttg gcagaaattc aagaaaaaat gtcacgattc ttgcggcaat atcgtagata
     6601 atgggagtgg gaaagaactc aaccattcat aagaagagtt cgtcaacaag tctttatttc
     6661 tagttgttga gctgaaacag tctattccca gactgtttcg ctcccacctc cgcacagctc
     6721 aaactgtctg ggagacagtt tgaggttgga gatgaagcga actctgttcg catcagtcgt
     6781 ataggtcaga ttttgaatgt aaaacacgaa cgaatctgcc aatcaaccac tgcgctgaga
     6841 tgttgacact aactttgaga agcggtgctg ggctttttgc ccagcctatt tctttttgct
     6901 tggatgaaat tgtttgtgtt tttctaacaa cggtaaatat tctgataatt gttgaaattt
     6961 tatgtatttt ttgctatact gaaagcaatt acagagtaaa gaggaaaata tgacaacatt
     7021 attagagaag acacggaata ttacttctat tttgaagcgt tccgaagagc aattggcaga
     7081 agaattgcct tacaatgcta ttgctgaaca tctatcagct attattgatt gcaattcttg
     7141 tattattaat agcgaaggtg aagttttggg ataccacatg agttacgaga caaacaatga
     7201 tcgtgtggaa gaatttttcc aaaacaaaca attcccagaa ggatatgtaa aagcagttgc
     7261 gcaggtttac gatacgcagg ttaatttgcc tgtcgagagc gagttgactg ccatccctgt
     7321 cgaatcacgc tcgacttatc caaacgggct gacaacgata gcgcctatcc acgtaacggg
     7381 gattcgtttt ggttcgctta ttatttggcg gaatgatgag cagtttcacg atgatgattt
     7441 gattttggtt gagattgcgg caacagtagt tggtattcag ttacttaatt tccaacggga
     7501 agaagacgag aagaatatcc gtcgtcgtgc ggcagttaat atggcggtaa atacgctatc
     7561 ttactcagaa atgaaggcag ttgcagctat tttgggtgaa ttggatggca atgaggggca
     7621 attgactgct tctgtgattg cagatcgtat cggtattaca cgatcggtga ttgtgaatgc
     7681 actgcgtaag ttggagagtg cagggattat tgaaagtcgt tctttgggaa tgaaggggac
     7741 ttatttgaaa gttctcatcc cagctatttt tgatgaaatt aagaaacgtg actactaaaa
     7801 tgacaaaagc attgattata tagtagattt tgtggcagat gaaggaaagc tgactgctgg
     7861 aaaatcagct caggctattt ctaaacgaat tgctcaggtt acgcaagaag cttttgaaaa
     7921 tggagactat attttctttg cgattgatgg tcatgaggag ggggatgaat ttcatcctga
     7981 agctcagctt ttcccaagtc ataatatcat tgggacgcaa gggcgtgact tgtatggtcc
     8041 tttagcagat ttttatcaaa aacataaagg gcatgcgcgt gttcgttgga tggataaacg
     8101 tcattattct actttttctg ggacggattt ggatgttcga ctaagagaac gtggtgtaga
     8161 tacggttgtc ttgacgggtg ttttgtctga tatttgtgtt cttcatacag ctattgatgc
     8221 ttataataag gggtatcgta ttgaggtggt ctcatcagcc attgctgcat tgacggagga
     8281 gaatcatcag tttgctctta accatttgcg tcatgtactc ggtgcgacaa ttattgatta
     8341 atagtatagt gaccagtctg tggactggtt tttacaggaa tctgtatcat taacactctt
     8401 cgaaaatcaa actcagacct tgttgactta acttgtaaaa gaagcggtgt gattgaccat
     8461 gataaattta tcaaaatgct ttacataggt gattacttgg tgtataatat agtctgtgtg
     8521 taatggacgc acaaaaatac agtttatccg ctgggtttaa aagcacctaa gattgacaaa
     8581 gataggagaa taaaatgaat ccattgatcc aaagtttgac agaaggtcaa cttcgtactg
     8641 acatcccttc attccgtcct ggtgacactg tgcgtgttca cgctaaggtt gtcgaaggta
     8701 accgcgaacg tatccagatt ttcgagggtg ttgttatctc tcgtaaaggt caaggcatct
     8761 cagaaatgta cactgtacgt aaaatctctg gtggtgtagg tgttgaacgt acattcccaa
     8821 tccacactcc acgtgttgat aagattgaag tagtacgtta cggtaaagta cgtcgtgcta
     8881 aattgtacta cctacgtgca ttgcaaggta aagcagcacg tatcaaagaa atccgtcgtt
     8941 aagatagtcc tacagactat tttggtcgga gaatgggagg cagcgaaagc tgtctctttt
     9001 tttaaaaaaa atctgttgaa aaagtaccaa attgtga
//
LOCUS       DBNFCO010000070         8954 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.070, whole genome shotgun sequence.
ACCESSION   DBNFCO010000070 DBNFCO010000000
VERSION     DBNFCO010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 8954)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8954)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8954
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.070"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            16..1656
                     /locus_tag="AC1PIV_001571"
     CDS             16..1656
                     /locus_tag="AC1PIV_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative polysaccharide biosynthesis protein"
                     /protein_id="HIP6612581.1"
                     /translation="MSEKVEMQQSKEQATMARGLAWLTAGNILSRLLGVAYVIPWYIW
                     LGEYRAEANALFSMGYQIYANFLLISTAGLPTAIAKQVAKYNVLGKEEVSLYLVREFF
                     KLMLVFGAVFAGVMYLSAPWLADASGSKEKLLPVMYSLVPPLFIFPAMSILRGFFQGR
                     HDMKPYAISQLAEQLVRVIWILAATFMIMKLGSGDYLEAVVQSTFAAFVGMIASVGIL
                     VYTLWKQGYLGKLLHAKKQKISLDTGQLIKETVRDAIPIIILGLTIQLLQFIDQVTFI
                     RVMERITDYSNSELLELYSYMAANPSKITMMIIGISLSLGSVAIPLITEKFVKKDLKA
                     ASHLVADNLQLLFIFTIPAIVGTVLLAGPLYTIFYGPSEPIAITLFIWNLFLILPLGL
                     YSVISVVIQAIFENRRAIYYFLIGMLVKIVLQVPMIYVFKVYGSFISTIFGLGIMLYL
                     FYRRIDKVLHIDERLVIKDIATISWISIVMGLVVWGIEFVLNLILPANGYVSSFIHLA
                     VAGGAGMLVFVILTLKTRQLDRLIGSRAQSLRRKLRLG"
     gene            1823..2557
                     /gene="pyrH"
                     /locus_tag="AC1PIV_001572"
     CDS             1823..2557
                     /gene="pyrH"
                     /locus_tag="AC1PIV_001572"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015445263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033862 - UMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HIP6612582.1"
                     /translation="MMKPKYERILIKLSGEALAGERGVGIDLKTVQEMAKEIQEVAES
                     GIQIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLKQLGVDTRVQ
                     TAIAMQSVAEPYIRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDANAVKFNELTHREVISRGLKIMDATASTLSMDNDIDLVVFNM
                     NEPGNIKRVVFGEPIGTTVSNSSEEK"
     gene            2692..3249
                     /gene="frr"
                     /locus_tag="AC1PIV_001573"
     CDS             2692..3249
                     /gene="frr"
                     /locus_tag="AC1PIV_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016481061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HIP6612583.1"
                     /translation="MSKEIIAKAQERMNQSHQSLAREFSHIRAGRANASLLDRISVEY
                     YGSPTPLNQLAGITVPEARVLLITPFDKSILKDIERALNASDLGLTPQSDGTVIRLVI
                     PALTEETRKNLAKDVKKVGENSKVAIRNIRRDAMDEAKKAEKAKEITEDELKTLEKDI
                     QKVTDDAIKTIDKMTADKEKELLEV"
     gene            3381..4235
                     /gene="cvfB"
                     /locus_tag="AC1PIV_001574"
     CDS             3381..4235
                     /gene="cvfB"
                     /locus_tag="AC1PIV_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HIP6612584.1"
                     /translation="MNDLLAQYIVGLVTDENDQFYFVQKEGRTFALSKDEGEHSLGQS
                     VKGFAYTDMKQKLRLTTKEVGASRTSFGWGTVTEVRKDLGVFVDTGLPDKQVVVSLDI
                     LPEIKELWPKKGDRLYVKLDVDKKDRIWALPAFQEDFQKMAGPAYDNMQNQNLRAIVY
                     RLKMNGTFVYLPDNNMLGFIHPSERFAEPRLGQVLEARVIGYRAVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSAPEDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DSFGTELV"
     gene            4245..5165
                     /locus_tag="AC1PIV_001575"
     CDS             4245..5165
                     /locus_tag="AC1PIV_001575"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000964166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HIP6612585.1"
                     /translation="MLVYIAGSGAMGCRFGYQLSKTNHEVILLDNWEEHIEAIRENGL
                     KVTGDVEETVYLPIMKPTEATREADFIILLTKADQLPKMLRDIKPIIGPTTKVLSLLN
                     GLGHATTMRRYVPDESIMVGVTMWLAGLKGPGHAHLEGPGSMSVQHILGDEQSVADII
                     EMLNEAGLNVTYDNHVVSAIWQKACVNGVMNPTCTILDCTIGELFGTEAGLNLVQGIF
                     KEFIAVAKSEADGIDEEAIWKYVIDASKKASNHYPSMHQDLVQHGRKTEIDYLNGAVV
                     FKGKRAGISTPYCQMITDMIHAKESMLGLR"
     gene            5175..5630
                     /locus_tag="AC1PIV_001576"
     CDS             5175..5630
                     /locus_tag="AC1PIV_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HIP6612586.1"
                     /translation="MLIEVETIEEYLAALPENRKEVVERLHQVIVEQLPAGFEVGILG
                     GMINYYVPLAAYPDGYHCTPGEPLPFLALASQKAHIALYHMGIYMDQELNDWFVAAYQ
                     AQVPTKLDMGKSCVRMKNPKNIPYELIGELVSKMSMERYIELYEKNHRK"
     gene            5636..5851
                     /locus_tag="AC1PIV_001577"
     CDS             5636..5851
                     /locus_tag="AC1PIV_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HIP6612587.1"
                     /translation="MRRSFYSWLMTQRNPKSNEPVAILADYAFDESDFPKQSDNFDEV
                     SRFLEESASFAFSMSDFDAIWEDYLGH"
     gene            5930..6952
                     /locus_tag="AC1PIV_001578"
     CDS             5930..6952
                     /locus_tag="AC1PIV_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HIP6612588.1"
                     /translation="MLEHSIDIQLKHPDDSFSLFGSNERHLRLMEQELGVVIHARTEK
                     VQVIGQEEHVEQARLVIQSLLVLVSRGLVINTPDVVTAISMAKNDEIEKFVALYEEEI
                     IKDNYGKPIRVKTLGQKLYVDSVKRHDIVFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IVLTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKEQTTRLMEREIIEIAP
                     LAYMRGRTLEDAFVILDEAQNTTIMQMKMFLTRLGFNSKMIVNGDISQIDLPRKVKSG
                     LIDATEKLSKIPQIDFVHFSAKDVVRHPVVAQIINAYEQEALAADGRASFETIGEPSR
                     KYNGEE"
     gene            complement(7622..8770)
                     /locus_tag="AC1PIV_001579"
     CDS             complement(7622..8770)
                     /locus_tag="AC1PIV_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-independent methionine synthase II
                     family protein"
                     /protein_id="HIP6612589.1"
                     /translation="MTTSRFQLVGSLLRPANLGEFKRQIEAREDIKYPFYDDFDGYKE
                     TEASLIQKIVAEQKENGLDIVTDGEFGRSMWHLDFLWGFDGIERYIAEHGYPFKDHDG
                     QIFETRKDIGLRITAPLSAKNHHFIDIFKQVKELAGETVTKQTIFGPAHAFNELTIFN
                     GQVGPNQVYKTRDELKVGLIAAYKEFLDQYKEAGGQIVQFDDCLWELFDPANPVPFLP
                     QDDSEALAALADEFVAINNAVIDYGHEIGLTVWTHNCRGNYESRSAAGGTYEAIAEKF
                     LRDQKYDRFFLEWDDERAGDLKALESLRDKNVEVVLGLLSSKTSDLDDEERVYKLLEE
                     ASKIIPKERLYLSHQCGFASCDSGNELAIPQQWAKIKQGQEIAEKFWS"
BASE COUNT         2597 a         1611 c         2071 g         2675 t
ORIGIN      
        1 gaaagtaata gaaaaatgtc cgaaaaagtt gaaatgcagc agtccaaaga acaggcgaca
       61 atggccagag gcttggcttg gttgactgct ggaaatattc ttagtcgcct gcttggtgtt
      121 gcttatgtta ttccctggta tatttggtta ggggaatatc gagctgaagc caatgccctc
      181 tttagtatgg ggtatcaaat ctatgccaac ttcttattga tttcaacagc tggtcttccg
      241 acagctattg ctaaacaagt agctaaatac aatgtcttgg gtaaagaaga ggtgtcgctt
      301 tacttggtca gagaattctt caagctcatg ttggtctttg gggctgtctt tgcaggggtc
      361 atgtatctaa gtgctccgtg gttggcagac gcatcggggt cgaaagaaaa gttacttcca
      421 gtcatgtata gtctagtccc gcctctcttt atcttcccag ccatgagtat cttgcgtggt
      481 tttttccaag gtcggcacga tatgaagccc tatgcgatca gccagcttgc agagcaactg
      541 gtacgggtta tctggatact ggcagcaaca tttatgatta tgaagttggg tagcggtgac
      601 tatcttgaag cggttgtcca atctaccttt gcagcttttg tcgggatgat tgctagtgtt
      661 gggattttag tttatacttt atggaagcaa ggttaccttg gtaagttgct tcatgctaag
      721 aaacaaaaga tttctttgga tacaggtcaa cttattaagg aaactgttcg agatgcgatt
      781 ccaattatca ttttaggtct aacgattcaa ttattgcagt ttattgacca agtcacgttt
      841 attcgtgtta tggaaagaat tacggattac agtaattcgg aacttttgga actttattca
      901 tatatggctg ccaatccaag taagattacg atgatgatta tcgggatttc acttagtttg
      961 ggaagtgttg ctattccatt gattacagag aaatttgtca agaaagattt gaaggcggcg
     1021 tctcatttag tggcggataa tctacaatta ctctttatat tcactatacc ggcaattgtt
     1081 ggaacagtcc tgttagctgg gccactttat acgatttttt acggaccgtc agagcctatc
     1141 gccattactc tatttatttg gaacttattt ttaattttac ctctgggact atattctgtc
     1201 attagtgtgg tcattcaagc gatatttgaa aatagaagag ccatttatta tttcttgatt
     1261 gggatgctag tgaaaatcgt tttacaagta ccaatgatct atgtctttaa ggtatatggt
     1321 agctttatct caacgatatt tgggttggga attatgctgt acctcttcta taggcgaatt
     1381 gacaaggttc tgcatattga tgaaagacta gtgataaaag atattgcgac cattagttgg
     1441 atttctatcg taatgggact cgttgtatgg gggattgaat ttgtcttgaa tcttatcctt
     1501 ccagcaaatg gctatgtatc tagctttatc cacttggctg ttgcaggtgg agcaggtatg
     1561 cttgtctttg tcatcttgac attgaagact cgtcagctag atcgtttaat tggaagtcgg
     1621 gctcagagtt tacggaggaa attgcgccta ggctagtttg ttttaaagat ctctattttc
     1681 tactattgaa aagctgggaa aaagaggcgt tttagaatgt gagaaggaaa gttcgttgag
     1741 gattttcctt ttttcttgga gatttcagta taaaaaaaac ggtttttgtg gtagaatagt
     1801 agggataaaa aagaggagag agatgatgaa acctaaatac gaacgtattc taatcaaact
     1861 atctggtgaa gccttggctg gtgaacgtgg tgtcggtatt gaccttaaaa ctgttcagga
     1921 aatggcaaag gaaattcagg aagtcgcaga atcaggtatt cagattgccc ttgttattgg
     1981 tggtggtaac ctttggcgtg gagagcctgc tgctgaagcg ggtatggatc gagttcaagc
     2041 agactataca ggcatgttgg ggactgttat gaatgctctt gtaatggctg attcccttaa
     2101 acagcttggt gtggatacac gtgtgcagac agcgattgcg atgcagtcag ttgcagagcc
     2161 ttatattcgt ggtcgtgctc ttcgtcatct tgaaaaaggt cgcattgtta tttttggagc
     2221 tggtattggt tctccgtact tctcaacgga tacgacagcg gctcttcgtg ctgcagaaat
     2281 tgaagcggat gcgattttga tggctaaaaa tggtgtggat ggcgtctaca atgctgatcc
     2341 gaagaaagat gctaatgcag ttaaattcaa tgaattgacc caccgtgaag tgattagtcg
     2401 tggtttgaaa atcatggatg cgacagcatc aactctctca atggacaatg atattgattt
     2461 ggtcgtgttc aatatgaatg aaccaggaaa tattaaacgt gttgtcttcg gtgagccaat
     2521 cggtactacc gtttcaaatt cttcagaaga aaaataaatc atatcgtcat ttagtttttc
     2581 ttttattact tcgttaattc gccttgtcta acttcggtta tgcctgtggc tcgttaccta
     2641 gtactaaaag taaactaaaa gactgtaaaa aaatacaaag aaggaagtct tatgtctaaa
     2701 gaaattattg ctaaagcgca agagcgcatg aaccaatctc atcagagttt ggcacgtgaa
     2761 ttcagccaca ttcgtgctgg ccgtgccaat gctagtttgt tggaccgtat ttcagttgag
     2821 tactacggtt ctccaacgcc attgaaccag ttggctggta ttacagtgcc agaagcgcgt
     2881 gttctattga ttactccgtt tgataagtca atcttgaagg atattgagcg tgctttgaac
     2941 gcttcagatc ttggtttgac accgcaatct gacggtactg ttatccgttt ggttattcct
     3001 gcccttacag aggaaactcg taagaacttg gcgaaggatg tgaaaaaagt cggtgaaaat
     3061 tcaaaagttg ccatccgtaa tatccgtcgt gatgccatgg atgaagctaa aaaagctgaa
     3121 aaagcaaaag aaatcacaga agacgagttg aagacgcttg aaaaagatat tcaaaaagta
     3181 acagatgatg ctatcaagac aattgataaa atgactgccg acaaagaaaa agaattgttg
     3241 gaagtttaat caacacgttt ttagactaca aaaatagatc atcactgggc tgtctaactt
     3301 ccagtggtga accaataaga aatctaatgg ggggagttag acaagacttc ccccactttt
     3361 taatcagaaa gaagaaaatc atgaatgatt tattagcaca gtatatcgtt ggtttagtga
     3421 ctgacgaaaa cgatcagttt tactttgtcc aaaaagaggg tagaaccttt gctctttcta
     3481 aggatgaagg cgaacatagt ctaggtcaat ctgttaaagg atttgcctat accgatatga
     3541 aacaaaaact ccgtttgaca actaaggaag ttggggcgag tcgtaccagc tttggttggg
     3601 gaactgtcac agaggtacgt aaggatttgg gtgtctttgt ggatacaggt ctaccagaca
     3661 agcaagtggt tgtttccttg gacattttgc ctgaaatcaa ggaactctgg ccgaaaaaag
     3721 gggatcggtt gtacgtcaaa ttagacgtcg ataagaagga ccgcatttgg gctctgccag
     3781 cttttcaaga agattttcag aaaatggctg gacctgctta tgataatatg caaaaccaaa
     3841 atctgcgagc gattgtctat cgtttgaaaa tgaatggtac ttttgtttat ttgccagaca
     3901 acaacatgct tggttttatc cacccaagtg aacgatttgc ggaaccacgt ctgggtcagg
     3961 ttttggaggc tcgtgtcatc ggctaccgtg cagttgatcg gaccttgaac ttgtctctca
     4021 agccacgttc atttgagatg ctggaaaatg atgctcagat gatattgact tatctggaaa
     4081 gcaatggagg tttcatgacc ttgaacgata agtctgctcc ggaagacatc aaggccacct
     4141 ttggtatttc caaagggcaa ttcaaaaaag ctcttggtgg tttgatgaag gctgggaaaa
     4201 ttaaacagga ttcttttgga acagagttgg tctagggggc gtctatgcta gtatatattg
     4261 ctggtagtgg ggcaatgggg tgtcggtttg gttatcaatt gtctaagaca aatcatgaag
     4321 tgattttgct ggataattgg gaagaacata tcgaagcgat tcgagaaaac ggcttgaaag
     4381 tgactggaga cgtagaggaa actgtatact tacccatcat gaaaccgacc gaagcaacga
     4441 gagaagcaga ttttattatt ctactgacaa aggctgatca gttgccaaag atgttgcggg
     4501 atattaaacc gattatcggt ccaactacca aggttttgag tctcttgaat ggtttggggc
     4561 atgcgacgac catgcgtcgg tacgtgccag atgaaagtat tatggttggg gtgaccatgt
     4621 ggttggcggg actaaagggt cctggacatg ctcacttaga aggtccgggt tctatgtccg
     4681 ttcagcatat tcttggtgat gagcaatcag ttgcggatat tattgaaatg ctgaatgaag
     4741 ctggactaaa tgtgacctat gacaatcatg ttgtcagtgc tatttggcag aaagcctgtg
     4801 tcaatggtgt gatgaatcca acttgtacca ttttagactg tacaattggt gaattatttg
     4861 gtacggaggc tggactaaat ctagtacagg ggattttcaa agaatttatt gctgttgcta
     4921 agtctgaggc agatggaatt gacgaagaag ctatttggaa atatgttatt gatgcttcga
     4981 agaaggcttc caatcactat ccatctatgc accaggattt ggtccaacat ggtcgaaaga
     5041 cagaaattga ttatctgaat ggagcggttg tttttaaggg caaacgtgca ggtatctcta
     5101 cgccatactg tcagatgata acagatatga ttcatgccaa ggaaagtatg ttggggttga
     5161 gataggagaa agtcatgctg attgaagtgg aaacgattga agaatatttg gctgccttgc
     5221 ctgaaaatcg gaaggaagta gttgaacggc tccatcaagt gattgtggaa cagttaccag
     5281 ctggttttga agtaggaatc ttgggaggta tgattaacta ttatgtgccg cttgctgcct
     5341 accccgatgg ttatcattgc acaccgggag agcccttgcc attccttgct ttggcatcac
     5401 aaaaggcaca catcgccctc taccacatgg gaatctatat ggaccaagaa ttgaatgatt
     5461 ggttcgttgc tgcttatcaa gcacaggtgc ctaccaaact ggatatgggc aagtcctgtg
     5521 ttcgtatgaa aaatcccaag aatattcctt atgaattgat tggggaattg gttagtaaga
     5581 tgtctatgga gcgctatata gagctctacg aaaaaaatca tagaaagtag atgtagtgag
     5641 aagaagtttt tattcttggt tgatgaccca gcgcaacccg aaaagtaatg aaccagtagc
     5701 tatcttggca gattatgcct ttgatgaatc tgattttcct aagcaatcag ataatttcga
     5761 tgaagtcagt cgttttttgg aggaatcggc cagctttgcc ttttccatgt ctgattttga
     5821 tgcgatttgg gaagattatt tgggacattg atggataaaa tagtacaaaa tagccttgtt
     5881 tgggctattt ttgttataat agagaaaagc acaggaaaag gagcaactct tgctagaaca
     5941 ttcaattgat attcaactca agcatccaga tgattcattt agcctatttg gttcgaatga
     6001 acgccatctg agattgatgg aacaggaact aggtgtggtt attcatgccc gtacggaaaa
     6061 agtgcaggtg attggacagg aagaacatgt agaacaggcg cgtcttgtta tccagtctct
     6121 ccttgtcttg gtgagtcgtg gtttagttat caatacgcca gatgtggtca cagctatttc
     6181 catggcaaaa aatgatgaga ttgagaaatt cgttgccctc tatgaagaag agattatcaa
     6241 ggacaactat ggcaaaccca ttcgcgtaaa gacccttgga caaaaactct atgtggacag
     6301 cgtaaagcgt catgatatcg tgtttggaat tggaccagct ggtacaggaa agaccttctt
     6361 ggcggttact ctagctgtaa cagccctcaa gcggggacag gtcaagcgga ttgtcctgac
     6421 ccgtcctgcg gtagaagcag gtgaaagttt aggcttttta ccaggggact taaaagaaaa
     6481 agtagaccct tatttgcgtc ctgtctatga tgccctctac cagattttgg gcaaggagca
     6541 gaccacgcgc ctaatggagc gcgagattat cgagattgca ccgctggcct atatgcgggg
     6601 tcggaccttg gaagatgcct ttgtcatctt ggatgaggcg caaaatacga ccattatgca
     6661 gatgaagatg ttcctgaccc gtctgggctt taattccaag atgattgtca atggggatat
     6721 tagtcagatt gacctgccac gcaaggttaa gtcaggcctg attgatgcga cagagaaact
     6781 aagcaaaatt ccgcagattg attttgtaca tttttcagcc aaggatgtgg ttcgtcaccc
     6841 agttgttgcc cagattatca atgcctatga gcaggaggct ctggctgcgg atggtcgagc
     6901 aagttttgaa acgattgggg agcctagtcg gaaatacaat ggcgaagagt agttgtttca
     6961 ttggctgata tataaaagaa ttgtgatgct agttacattt aatatacaat aaaaagccca
     7021 aatggacgat actgtaagcg atgaaacaaa caggaactta gtccaaataa gcgacttaca
     7081 gcatatcgta aaatcacatc gtacagcaaa tatcaactat ttgtcacaag ttataccaat
     7141 cctattgccc gactccctta aagcattgtc acaacgttgc tttgtcaacg gtatcatata
     7201 aatctattaa aatattgcta gtacttcaag ttggattaga gattaaatct taacgacatt
     7261 ttcgaaccag ccctcattat agcggataga gatcataaaa cctataactt tatggattgt
     7321 taccaataaa aaggctggtt ctatctgatt cggattcgag atgggaaaag cagcatgaaa
     7381 ccgagtttta ctccctttct tttcgcatgt tcggcaccga taagtatgaa accctcgtgg
     7441 ccaattgtga taaacctgta gactatataa aaaagcctcc ctttgtgttg tccgaacata
     7501 aaatcccaag tattacatcg gaaaaatact tgggattaga tatcatagat taactgatca
     7561 gagttaactt agagacactg attgatgaca gggcttttat gcacgaataa caagaagtgg
     7621 cttaagacca aaacttctct gcaatttctt ggccttgttt aatttttgcc cactgttgcg
     7681 ggatggccaa ttcattacct gaatcacatg aagcgaatcc acattgatgt gacaagtaga
     7741 gacgctcttt tggaataatc ttgcttgctt cctcgagtaa tttgtaaaca cgttcttcat
     7801 catccaaatc agaagtttta cttgaaagta gaccaagaac gacttcgaca ttcttgtcac
     7861 gcaagctttc caaagctttt aaatcacctg cacgttcatc atcccactca aggaagaatc
     7921 gatcgtattt ttggtcacgc aggaattttt cggcaatagc ttcgtaagtt ccgccagctg
     7981 cagagcggct ttcatagtta ccacggcagt tgtgcgtcca gacggtcaag ccaatttcat
     8041 gtccgtaatc aataacagca ttattgatag caacaaactc gtcagccaaa gcggccaatg
     8101 cttcagaatc gtcttgtggc aagaaaggta cagggttagc agggtcaaat aattcccaaa
     8161 ggcagtcatc aaattgaacg atttgtccac cagcttcctt gtactggtct aaaaattcct
     8221 tataggcagc gatgagcccg acttttaatt catcacgagt cttgtagacc tgatttggtc
     8281 caacttgtcc attgaaaatt gtcaattcat taaaggcatg ggctggaccg aaaatagttt
     8341 gtttggttac agtttctcct gctaattctt tcacttgttt gaaaatatca atgaaatggt
     8401 gattttttgc agaaagtgga gcagtaatac gcaatccaat atccttacgt gtttcaaaaa
     8461 tctgtccatc atggtcttta aatggataac catgctcagc aatgtaacgc tcgataccgt
     8521 cgaagcccca gagaaaatct aggtgccaca ttgaacgacc aaattctcca tctgtcacaa
     8581 tatccaaacc gttttctttt tgttctgcaa caattttttg gatgagtgaa gcttcagttt
     8641 ctttgtaacc atcgaagtca tcatagaatg ggtatttgat gtcttcacga gcttcgattt
     8701 gtcgtttaaa ttctcctaag tttgctggtc gaagaagtga accgactaat tggaatcttg
     8761 aagttgtcat atgtgtgtct ctctttcgtt ttagtgatga acctattcta actcataagc
     8821 tatcatttga aaaatagtta ttttcatggc aaatccatag ttaaaaacta taacttgaaa
     8881 aaatagaagg aaataacttt ctatcatttg tcaactatgg tataatcaaa agtgctgaaa
     8941 tccgaacatt agga
//
LOCUS       DBNFCO010000071         8781 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.071, whole genome shotgun sequence.
ACCESSION   DBNFCO010000071 DBNFCO010000000
VERSION     DBNFCO010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 8781)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8781)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8781
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.071"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(<1..1076)
                     /locus_tag="AC1PIV_001580"
     CDS             complement(<1..1076)
                     /locus_tag="AC1PIV_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HIP6612590.1"
                     /translation="MKKETSKFTKKVILGQLLICTSFLVWAGQTVAAEEVSQGEPVAI
                     NNETPPVIEAKPLVEATPSTETEPSTPEEKQEEPQVAGKNVVEGKKPVTNSQHQMVSE
                     LSTVPSVSIKNPDAATDGSAYGSSDDANSNTKIIAGKETGEPDNGYSKWDHVYVQYDF
                     EKEVPVHTVKIHRNTYDNAVSTFKDVKVELSTSADFSPETTEVIFKQADVEETIANKG
                     QPQVIQLPAPINARYIRIWGRGHYIQNTNSSWKGYSNGVLFNEIEVLAQVEADAGTNE
                     EPQTELVNLAKLKKPYFYGKAPTNPEAINDGKFDENYTTQESIGDKAYLQYEFRNVYT
                     IEEIKVQLAPGEYRNFRIDLDDDY"
     gene            complement(1447..2787)
                     /locus_tag="AC1PIV_001581"
     CDS             complement(1447..2787)
                     /locus_tag="AC1PIV_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HIP6612591.1"
                     /translation="MRTSFIQSSHQEACIQAIQELVAFPSVLQEHQADTPFGQAIQDV
                     LEHTLALTEKMGFKTYLDPAGYYGYAEIGQGEELLAILCHLDVVPAGDLSQWQTPPFE
                     AVVEGDYIIGRGVQDDKGPSMAALFAVKALLDAGVQFNKRIRFIFGTDEETLWRCMNR
                     YNQLEEVATMGFAPDSSFPLTYAEKGLLQAKLHGPGHPCLSIEAGTAYNVVPAKASYS
                     GHLLAGVIAELDQLGFDYEIKDDQVTVLGISRHAKDAAEGVNAIVRLAKALEHFENHP
                     ALDFIVNAVGEDATGFKLFGDVTDEPSGTLSFNIAGLTISAKKSEIRLDIRIPVTADK
                     EALVSTLQAKAQSCGLTYEEYDYLASLYVPLDSQLVSTLMSVYQDKTGDLTSEPISSG
                     GATFARTMPNCVAFGACFPDTEQTEHQENERMPLEDLYKTMDIYAEAVYRLTAE"
     gene            complement(2906..4408)
                     /locus_tag="AC1PIV_001582"
     CDS             complement(2906..4408)
                     /locus_tag="AC1PIV_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HIP6612592.1"
                     /translation="MSEKVKKGFKLPSSYTILMLIIAFMAVMTWVIPAGQYQVDEAGR
                     LVAGTYEKVAQNPQGIYDVFMAPVRAMLGHGATEAAINVAFFIIMVGAFLGVVNETGA
                     LDVGIASIVKRFKGREKMLIYILMPLFALGGSTYGMGEETMAFFPLLVPVMMAVGFDS
                     ITGVAIILLGSQIGCLASTVNPFATVVASDAAGVSVADGMIWRFVFFVVILAMGVLFV
                     ANYAEKVKNDPTKSLVYKQREADMQHFNVAATQEVNAELSPAQKRVLWVFVLTFVLMI
                     CSFIPWEDLGVTIFTQFNDWLIGLPFIGQVIGSSTAALGTWYFPEGAMLFGIAGIVVG
                     LVYGMSEERLVKSFMFGAADIFSVALICAIARGIQVIMNDGMITATILHMGEEGLQGL
                     SSQVFIILTYLFYLPMSFLIPSSSGLAGASMGIMAPLGEFVNVPASLVITAFQAASGL
                     LNLVAPTSGIVMGALALGRVEIGTWYKFVGKLIVGIMIASIAILVIATFF"
     gene            complement(4751..5698)
                     /gene="arcC"
                     /locus_tag="AC1PIV_001583"
     CDS             complement(4751..5698)
                     /gene="arcC"
                     /locus_tag="AC1PIV_001583"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008804 - carbamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HIP6612593.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQKEALVQTAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQNLAADSEKNPAFPLDSLVAMTEGSIGFWLQNALENELLKE
                     GIEKDVASVVTQVIVDKNDPAFENLTKPIGPFYTEEEAKAEAEKTGATFKEDAGRGWR
                     KVVASPKPVGIKEIGTIRTLLNAGEVVVAAGGGGIPVVQEADGTLTGVEAVIDKDFAS
                     QCLAELVDADLFIVLTGVDYVFVNYNKPDQEKLETVTVAELEEYIKQNQFAPGSMLPK
                     VEAAIAFVNNKPQSKAVITSLENLGALIESDSGTIIVKG"
     gene            complement(5816..6829)
                     /gene="argF"
                     /locus_tag="AC1PIV_001584"
     CDS             complement(5816..6829)
                     /gene="argF"
                     /locus_tag="AC1PIV_001584"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000195397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - L-arginine biosynthetic process
                     via ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HIP6612594.1"
                     /translation="MTNVFKGRHFLAEKDFTRAELEWLIDFSAHLKDLKKRNIPHRYL
                     EGKNIALLFEKTSTRTRAAFTVASIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMF
                     DGIEFRGFSQKMVEELAEFSGVPVWNGLTDAWHPTQMLADYLTVKENFGKLEGLTLVY
                     CGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEEEVVALAEGFAKESGARVLITDNA
                     DEAVKGADVLYTDVWVSMGEEDKFAERVALLKPYQVNMELVKKAENENLIFLHCLPAF
                     HDTNTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGDPFV
                     PRV"
     gene            complement(6848..7288)
                     /locus_tag="AC1PIV_001585"
     CDS             complement(6848..7288)
                     /locus_tag="AC1PIV_001585"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIP6612595.1"
                     /translation="MPSIERTTIGSEEWQRAASIYVRYKVFVLERGIAKEDEFDQNDT
                     EERVYANLFIGEEPVSTGRFLPVGPGQARLTRIATLPNFRGKGYGKMIISSLEAYARE
                     AGFHQLNIHSELTAKTFYESVGYQATSEVYQEDGEWCQTLTKFI"
     gene            complement(7288..8517)
                     /gene="arcA"
                     /locus_tag="AC1PIV_001586"
     CDS             complement(7288..8517)
                     /gene="arcA"
                     /locus_tag="AC1PIV_001586"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016990 - arginine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0019546 - arginine deiminase pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HIP6612596.1"
                     /translation="MSNHPIHVFSEIGKLKKVMLHRPGKEIENLMPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGVEVLYLEKLAAESLVTPEIREQFIDEYLEEANIRGRAT
                     KKAIRKLLMSIEDNQELVEKTMAGVQKAELPEIPSEEKGLTDLVESSYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMYSETRNRETLYGKYIFTHHPEYGGKVPLVYNREETTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFERHVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLRVFSVTYENDTLHIEEEHGDLAELLAANLGLEKVELIR
                     CGGGDMVAAGREQWNDGSNTLTIAPGVVVVYKRNTITNAILESKGLRLIKIGGSELVR
                     GRGGPRCMSMPFEREDI"
BASE COUNT         2568 a         1982 c         1609 g         2622 t
ORIGIN      
        1 ttataatcat catccaaatc tatccggaaa ttacgatact ctccaggagc taactgaacc
       61 ttgatttcct caatagtata gacatttcta aattcatatt gaagataagc tttatcccct
      121 attgattctt gagtagtata attctcgtcg aactttccat cgttaatggc ttctggatta
      181 gttggagcct taccatagaa atatggtttt ttcaatttag cgaggttgac tagctcggtt
      241 tgtggttctt cattcgtacc agcatctgct tcaacctgcg ccaagacttc tatctcgtta
      301 aagagaacgc cattactata tcccttccag gaactgtttg tattttggat ataatgcccc
      361 cgtccccaaa tacgaatata acgagcattg attggtgctg gtaattggat gacttgaggc
      421 tgtcctttat ttgcaattgt ttcttctaca tctgcctgtt tgaaaatgac ttctgtggtt
      481 tcaggagaaa aatctgcact tgtagacaat tccactttaa catctttaaa agtagacact
      541 gcattgtcat aagtattacg atgaattttt acagtatgga cgggaacttc cttttcaaaa
      601 tcatactgaa cgtaaacatg atcccacttg gagtaaccgt tatctggttc gccagtttct
      661 ttaccagcaa tgattttggt attgctattg gcatcgtcgc tactaccgta agcactccca
      721 tcggtagctg catctggatt ttttatagaa acagaaggga ccgttgataa ttcagaaacc
      781 atctgatgct ggctgttggt tactggcttt ttcccttcta ccacattttt accagctact
      841 tgtggttcct cctgtttttc ttctggagtt gaaggttctg tttcagttga tggagtagct
      901 tctacaagtg gttttgcttc aataacaggt ggagtttcat tgttgattgc tactggttct
      961 ccctgagata cctcctctgc tgcaacagtc tgccctgccc ataccaaaaa actggtacag
     1021 atgagaagct gaccaaggat gacttttttc gtaaacttac ttgtttcttt tttcattatt
     1081 tcctcctata aagtctgcaa gtttatccta cctatagcca aaataaagca gtttgtaaac
     1141 ctatttagtc tcgtacaaga ctcaaaattc agtttactgg ttgatgtgcg atcgcatttc
     1201 tgtcacaaat ataacatgta agcgttttat tgtagaatag tccaacttga cttattctat
     1261 atgcagatgg ggtctatttc taaaacagca tataataagt cacactttca tatatttttg
     1321 tccacttctt gtaaacagtg acacatttct ctctcatctt tttaatgata ttcttcataa
     1381 gaaaagccct tagatatttc actaagagct tttaaactgt aatttactat tcaatgctga
     1441 taatggctat tccgcagtta ggcgatagac tgcctcagca taaatatcca ttgttttata
     1501 taagtcttct aatggcatgc gttcattttc ctgatgctct gtttgttctg tatctgggaa
     1561 acatgcacca aaagccacac agtttggcat agtacgagca aaggtagccc cacctgacga
     1621 gattggctcg cttgtcaaat ctcctgtctt atcttgataa acagacatga gcgtagatac
     1681 cagttgactg tctaatggca catacaagga agcaaggtag tcgtactctt cataggtcaa
     1741 gccacatgat tgcgctttgg cttgtaaagt agaaactagg gcttctttat ccgcagtgac
     1801 aggaatacga atgtccaagc gaatttctga tttttttgcg ctaatggtta gacctgcaat
     1861 attgaaactg agtgtccctg atggttcatc ggtcacatca ccaaaaagct taaatcctgt
     1921 ggcatcttca ccaactgcat tgacgataaa gtccaaggct ggatgatttt cgaaatgttc
     1981 caaagccttt gccaaacgaa cgatggcatt gaccccctcg gcagcatcct tggcgtgccg
     2041 cgaaatacca agaaccgtta cttgatcatc tttgatttca taatcaaagc ctaattgatc
     2101 taattccgca ataactccgg ctaataaatg accggaatag cttgccttgg caggtactac
     2161 gttataggca gttccagctt cgatactcag acaagggtga cctggaccat gcaatttggc
     2221 ctgtagtaat cctttttcag cataagtcaa agggaaggaa gaatctggcg caaagcccat
     2281 agttgccact tcttccaact gattgtagcg gttcatacac cgccataagg tctcttcatc
     2341 tgttccaaaa atgaaacgaa tccgtttgtt aaattggact cccgcatcaa gaagtgcttt
     2401 tactgcaaat aaggccgcca tcgaaggacc tttatcatcc tgaaccccgc gtccaataat
     2461 ataatctccc tctaccacag cctcaaaagg cggcgtctgc cattgactaa gatcaccagc
     2521 aggtaccaca tctaagtggc aaaggattgc taataattct tcgccttgcc caatttcagc
     2581 atagccataa tagccagcag ggtctaaata agttttaaaa cccatttttt ccgtcaaagc
     2641 caacgtgtgc tccagaacat cctgaatcgc ttgaccaaat ggcgtatctg cctgatgttc
     2701 ttgcaaaaca gaaggaaaag caaccagttc ttggatggct tgaatacatg cctcctgatg
     2761 cgatgactga ataaaacttg ttctcattgt gtcccctttc aacataataa gatatgatat
     2821 attttctagc actattctat cataaaagga aaaactgagc caaattttat ctgtattcgt
     2881 gataaaatct gacccagaat ttcgattaga agaatgtcgc aatgaccaaa atagctatgg
     2941 aggcaatcat gatgcctacg attaacttac ctacaaattt ataccaagta ccaatttcaa
     3001 cacgaccaag tgccaaggct cccattacaa tacctgatgt tggagctacc aagttcaaga
     3061 gacctgatgc agcttggaaa gctgtgataa ccaagctcgc tggtacattt acaaactcac
     3121 caagaggtgc catgataccc atagaagccc ctgcaagacc tgatgaagat ggaatcaaga
     3181 aggacattgg taggtagaag agatatgtca aaatgatgaa tacttgtgaa gacaaacctt
     3241 gcaatccttc ttcacccatg tggagaatag tggcagtaat cataccatcg ttcatgatga
     3301 cttgaatacc acgcgcgata gcacaaatca aagctacgct gaaaatatca gccgcaccga
     3361 acatgaagga ttttaccaaa cgttcttcac tcataccata aactaaacca actacaatcc
     3421 ctgcgatacc aaagagcatt gctccttctg ggaagtacca agtaccaaga gcagctgttg
     3481 aagaaccaat cacttgaccg atgaatggaa gaccaatcaa ccaatcatta aattgtgtaa
     3541 agatagtcac acccaaatct tcccatggaa taaagctaca aatcatgaga acaaatgtta
     3601 gtacaaatac ccagagaaca cgtttttgag ctggtgataa ttctgcattc acttcttgag
     3661 ttgctgcgac attaaagtgt tgcatgtccg cttcacgttg tttataaacc aaggacttag
     3721 tcggatcgtt tttcactttc tcagcatagt tggctacaaa gagaaccccc atcgcgagaa
     3781 tgacaacgaa gaagacaaag cgccaaatca taccatccgc aacacttaca cctgccgcgt
     3841 cagaggctac aactgtcgca aatgggttta cagtagaagc caaacagccg atttgagaac
     3901 ctagcaagat gatggctaca ccagtaatac tatcaaaacc aaccgccatc ataacaggaa
     3961 caaggagcgg gaagaaagcc attgtttctt cacccatacc ataggttgag cctcccaagg
     4021 caaacaaagg catgaggatg taaatcaaca ttttttcacg acctttgaag cgttttacaa
     4081 tagaagcaat ccctacatca agtgcacctg tttcgttaac tacaccaaga aaggccccaa
     4141 ccatgatgat gaagaatgct acgttaatcg ctgcttcagt cgcaccgtga ccaagcatgg
     4201 cacgaactgg agccataaaa acatcgtaaa tcccttgtgg attttgagca accttctcat
     4261 aggtaccagc caccaaacgt ccggcttcat caacctgata ctgaccagct ggaataaccc
     4321 atgtcatcac tgccataaag gcaataatga gcatcaatat tgtataagac gaaggcaatt
     4381 taaagccttt tttcactttt tcgctcatcg caaaaacctc ctataatatt ttaaaagttt
     4441 atcccctatt taagggaaat tgtatccgta ataaccgtat caaatatcca cctatcttca
     4501 agagatgtct atctccttca gtctattatc tgaaatcatt gcttatagat agatacttga
     4561 taggaaatgg atgagagggg agggagctta gacgcccaga ccttcatgtt tagattaaag
     4621 ggaacccttg tgggactatc aacacttcca ctcccctaac tccatcaata aataacccgt
     4681 ctagtttaaa aactatattt gcatgcagag tacatcaata aatagaagcc tcaacgatac
     4741 atacagctgc ttagcctttg acaatgatag tgccgctatc ggattcaatc aaagcgccta
     4801 agttttctaa tgaggtaatg actgcttttg attgcggctt attgtttaca aaagcaatag
     4861 ctgcttcaac tttcggtagc atggaacctg gtgcgaattg attttgtttg atatattctt
     4921 ccaattcagc cacagtaacg gtttctaatt tttcttggtc tggtttgttg tagttaacaa
     4981 agacatagtc tacacctgtc aagacgataa acaagtctgc atcaaccaat tctgccaaac
     5041 attgagaagc aaagtcctta tcgataactg cttccacacc ggtcagggtg ccatctgctt
     5101 cttggacaac tggaatacct ccgcctccag ctgctacgac aacttcacct gcattgagaa
     5161 gggtacgaat ggtaccaatt tctttgattc ctacaggttt tggcgaagca acgactttac
     5221 gccagccacg accggcatct tctttgaagg ttgcaccagt cttttctgct tctgctttcg
     5281 cttcttcttc tgtatagaat ggtccaatcg gcttggtcaa attttcgaag gcgggatcat
     5341 tcttatctac gataacctgg gtcacaacag atgctacatc tttttcaatg ccttccttga
     5401 gcaattcatt ttccaaggca ttttgcaacc agaaaccaat cgaaccttct gtcatggcta
     5461 ccaaactgtc tagtggaaaa gctgggttct tttccgaatc agcagcaagg ttttgaagaa
     5521 gtaagtttcc aacctgagga ccattaccat gcgtgataat aaggtcatcc ccatttttta
     5581 tcaattttac aaggtgcttg gctgtttgta ccaaggcctc tttttgtgct ttagccgatg
     5641 ggtcggacga taaaatggca ttgccaccca aggctactac aattttacga tttgccatat
     5701 ctcttgcttt ttcctcactt tcgcgaaata gtaatcgctt acacatctat cctcaaaata
     5761 agggggctgg gtgccagccc ccggaggttg cgatgcgtta ttagatagtt aattattaca
     5821 cacgtggaac aaatggatcc cctaaagtag ccgccatcac tgctttaata gtgtgcatac
     5881 ggttttcagc ttggtcgaag tgacgagcat acttgctacg gaatacttcg tctgttactt
     5941 ccatttcttc tacgccgaat ttttcagcga catctttacc ataaacagtg tttgtatcat
     6001 ggaaggcagg caagcagtgc aagaagatga gattttcatt ttctgctttt ttcaccaatt
     6061 ccatattcac ttggtatggc ttcaagaggg caacgcgttc agcaaattta tcttcttcac
     6121 ccattgatac ccaaacgtct gtatagagaa catctgcgcc tttgactgct tcgtcagcat
     6181 tgtcagtaat gagaacacgt gctccacttt ctttcgcaaa accttcagcc aaggcaacta
     6241 cttcttcttc tgggaagagt tcttttggag agaagatatg gacattgaca ccaaggatag
     6301 cgcctgttac caaaagtgag ttagcaacat tgttacggcc atcaccacag taaaccagag
     6361 tcaagccttc caacttgcca aagttttctt tgacagtcaa gtagtccgcc aacatttgag
     6421 ttgggtgcca tgcatctgtc aaaccattcc atactggcac accggagaat tctgccaatt
     6481 cttccaccat tttttgactg aaaccacgga attcaatacc gtcgaacata cgtcccaaaa
     6541 ctttagcagt atcttctgta gattctttct taccaagttg gatgtcattt gcaccaagat
     6601 attctggatg ggcaccaagg tcaatagatg ctactgtgaa ggcagcacga gtacgtgttg
     6661 atgttttttc aaacaagaga gcaatatttt taccttccaa ataacggtgt ggaatattgc
     6721 gttttttcaa atctttcaaa tgagctgaga aatcaatcaa ccattccaat tctgcgcgtg
     6781 tgaaatcttt ctctgcaagg aaatgtctac ctttaaatac gtttgtcatt gtctcttctc
     6841 ctaatgttta aataaatttt gtcaatgtct ggcaccattc tccatcttct tgataaactt
     6901 cagaagttgc ttggtagcca actgactcat aaaaagtctt tgcagttaac tccgaatgta
     6961 tattcaactg atgaaagcct gcttcacgtg catacgcttc caaagagctg ataatcattt
     7021 ttccatagcc ttttccacga aaattcggta gagtggctat tcgggttaga cgagcttgac
     7081 caggaccgac aggaagaaaa cgtcccgttg aaacaggctc ttcaccaata aagagattgg
     7141 cgtaaactct ttcttccgta tcattctggt caaattcatc ttcctttgca ataccacgct
     7201 caaggacaaa taccttatag cggacataga tagaggctgc gcgttgccat tcttccgaac
     7261 cgattgttgt tcgttctata cttggcatta gatgtcttca cgttcaaacg gcattgacat
     7321 acaacgaggt ccaccacgac cgcgaaccaa ttcgcttccg ccaatcttaa tcaaacgaag
     7381 ccctttggac tcgaggatag cattggtaat cgtattgcgt ttgtaaacaa ctaccacacc
     7441 tggtgcaata gtcaatgtat ttgaaccatc attccattgc tcacgaccag cagcaaccat
     7501 atcaccgcca ccacaacgaa tcaattctac tttttcaaga ccaaggttcg cagccaaaag
     7561 ttctgccaaa tcaccatgtt cttcttcaat atgaagcgtg tcattttcat aggttacaga
     7621 gaagacacga aggtcacctt cgatttctgg gtggatagta aacttatcat agtcaaccat
     7681 ggtaaatact gtatccaaat gcatgaattt acggttgtta gcaaattcga atgccaatac
     7741 tttcttgaag ccaacatgcc gttcaaagat atttaccaat agtttttcaa ttgatgccgc
     7801 atcggtacgt tgtgaaatac ctactgccaa aacatctttt gaaagaacca attcgtcacc
     7861 accctctata cgagtagttt cttcacgatt gtaaaccaat ggaacttttc caccatattc
     7921 tgggtgatga gtgaagatat atttaccata caaggtttca cggttccgtg tttctgaata
     7981 catgtggtta agagaaacag cattaccaat cgtagcaaat ggatcccgtg tgaagtaaag
     8041 gtttggcatt gggtctattg caaatgggta agaggattca accaaatctg tcaaaccttt
     8101 ttcttcagaa gggatttctg gcaattctgc cttttgaaca ccagccatcg ttttctcaac
     8161 cagttcttga ttatcttcaa tagacatcaa cagcttacga attgcctttt tagttgcccg
     8221 gccacgaatg ttagcttctt caagatattc atcaataaat tgttcacgaa tttcaggtgt
     8281 aacaagtgac tcagcagcta atttttccaa gtagagcact tctacacctt catcacgaag
     8341 agcttgagca aaggcatcat gctctttctg tgcatcttct aagaatggga tatcatcgaa
     8401 gagtaggcgt tctagatagt caggcataag gttttcaatt tccttacctg gtctgtgtaa
     8461 cataactttt ttcagcttac caatttctga aaaaacatga attggatggt ttgacatgat
     8521 ctgtcctcct tgtagattta tacatgatgg gaaacgagga ggaccgtacg ctttcctgcc
     8581 tctcatttcc tctttacatc catagtttaa cagagcaaaa aaacaaaaac ttgaaaacgc
     8641 tcacatttat tttgagaaat tcttcacatt tttaacctta tttataaata attatcgatt
     8701 atatcatcta aattctgcat aattctttcc gttatatcat tatatgaatt tttatttttt
     8761 tataaaaaac agaaacttca a
//
LOCUS       DBNFCO010000072         8617 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.072, whole genome shotgun sequence.
ACCESSION   DBNFCO010000072 DBNFCO010000000
VERSION     DBNFCO010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 8617)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8617)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8617
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.072"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            21..1037
                     /locus_tag="AC1PIV_001587"
     CDS             21..1037
                     /locus_tag="AC1PIV_001587"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HIP6612597.1"
                     /translation="MTKQTIAILGPGSWGTALGQVLNDNGHTVRIWGNVPEQIDEINK
                     EHTNKRYFKDVILDENIKGYKDLSEALDGVDAVLFVVPTKVTRLVAKQVAQALKHKVV
                     VMHASKGLEPDSHKRLSEVLEEEIPAELRSEIVVVSGPSHAEETIVRDLTLISAASKD
                     LETASYVQNLFSNHYFRLYTNNDVIGVETAGALKNIIAVGAGALHGLGYGDNAKAAII
                     ARGLTEITRLGVAMGANPLTYSGLSGVGDLIVTGTSVHSRNWRAGDQLGRGEKLEDVE
                     RNMGMVIEGISTTKAAYELAQELGVYMPITQAIYKVIYQGAGIEDAIKEIMTGEFRHE
                     NEWH"
     gene            1082..1981
                     /gene="galU"
                     /locus_tag="AC1PIV_001588"
     CDS             1082..1981
                     /gene="galU"
                     /locus_tag="AC1PIV_001588"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-alpha-D-glucose metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HIP6612598.1"
                     /translation="MKKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEE
                     ALRSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKNDLLKLVDETTGIRLHFIR
                     QSHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDTKAVPLTKQLMNDYEKTHASTI
                     AVMPVPHEEVSAYGVIAPQGEGVNGLYSVETFVEKPKPEDAPSDLAIIGRYLLTPEIF
                     EILENQKPGAGNEIQLTDAIDTLNKTQRVFAREFKGNRYDVGDKFGFMKTSIDYALQH
                     PQVKDDLKQYLIDLGKKLDTKKN"
     gene            complement(1999..2676)
                     /locus_tag="AC1PIV_001589"
     CDS             complement(1999..2676)
                     /locus_tag="AC1PIV_001589"
                     /EC_number="3.4.21.-"
                     /EC_number="3.4.21.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HIP6612599.1"
                     /translation="MKNFFDKRYPVTNGLLAVTALVFLLIQVFRFGQTTTAYTIFEFG
                     GMYGQVVRYDPTQLWRLISPIFVHIGWEHFIFNSITLLGLGYQLEGLFGSRRFFLLYL
                     LSGIMGNLFVLFFTPDVVGAGASTSLFGLFAAMALLRKFSRSPYLQVLGQRYMVLLGL
                     NLVLGLFNPTISMAGHIGGAVGGCLVVMFLPPLVEKDLFTGKQIFFSFIGYLGLIALL
                     LGIFYLT"
     gene            complement(2660..3202)
                     /locus_tag="AC1PIV_001590"
     CDS             complement(2660..3202)
                     /locus_tag="AC1PIV_001590"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HIP6612600.1"
                     /translation="MDKKSIRQEVLQSLKDLTSSQRARWSQQLTERLLASDTYQGAKS
                     LGTYLSMPHEFDTSYLIEQAQKDGKQIFIPKTYSQGRMDFVEYNPDDLVKSRFGVWEP
                     GIYSQPVDKSVVKLLHVPGLAWNQAGFRVGYGGGFYDRYLADYQGETVSTLADFQVYD
                     FEPDVFDIPVKELLIFEELF"
     gene            complement(3243..4370)
                     /locus_tag="AC1PIV_001591"
     CDS             complement(3243..4370)
                     /locus_tag="AC1PIV_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HIP6612601.1"
                     /translation="MLDLIATRRALHQIPELGMEEFKTHAFLMETIEGLLQDCSFAQV
                     RTWKTGILVYLTGSAPEKTIGWRADIDGLPIVEETGLDFKSLHPDRMHACGHDFHMTI
                     ALGLLEKMAEQQPRNNLLFLFQPAEENLAGGMLMYEAGAFGDWLPDEFYGLHVRPDLK
                     VGQMATNRATLFAGTCEVKIRFTGKGGHAAFPYTANDALVAASYFVTQVQSVVSRNVD
                     PIEGAVVTFGSMHAGTTNNVIAETAFLHGTIRALTQNMSLLVQKRVREVAEGIALSFG
                     VDLEIELNPSGYLPVENNPQLADELMTYFDGIDGVEMIDCPPAMTGEDFGYLLNKVPG
                     VMFWLGVDTPYPLHNPRLSPKEEVLPFAVDKLSDFLKMKAN"
     gene            complement(4380..5078)
                     /gene="dapD"
                     /locus_tag="AC1PIV_001592"
     CDS             complement(4380..5078)
                     /gene="dapD"
                     /locus_tag="AC1PIV_001592"
                     /EC_number="2.3.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047200 - tetrahydrodipicolinate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HIP6612602.1"
                     /translation="MTAQKMTAQEIIAFIGNAVKKTTVKVTFEGELAGAVPAEVTKLG
                     NVLFGDWKDVEPLLANLTENVDYVVEQDGRNSAVPLLDKRNINARIEPGAIIRDQVTI
                     GDNAVIMMGAVINIGAEIGPGTMIDMGAILGGRATVGKNSHIGAGAVLAGVIEPASAE
                     PVRVGDNVLVGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEEALRTL"
     gene            complement(5353..5820)
                     /locus_tag="AC1PIV_001593"
     CDS             complement(5353..5820)
                     /locus_tag="AC1PIV_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612603.1"
                     /translation="MSKDDYSSTRKQEFEQILNSVDISDEVVESSSKTTETPTSSEST
                     ATVSEFNPTDSSDATIESIKTYSDYMKMYEFIVNEYITNYENMVSQYGLGDATMYQSV
                     RDTVSQSVEQQKKQYGPLGNAAIVGRAEIITFLKEYRDGLQQQIEQMSAALGG"
     gene            complement(5807..6343)
                     /locus_tag="AC1PIV_001594"
     CDS             complement(5807..6343)
                     /locus_tag="AC1PIV_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612604.1"
                     /translation="MAKKIRDEHGNVYVQKKPFYKRIWFIVLVGLFAIGLIKNLTSSS
                     GGQSSTEQVSTSSIRYKTYQLSEVAISINESWKSKEGDTSDTLYFYPDDSSLAMAYWL
                     PLEESVKDATVRSQYLKGMEQSGKVIPANESSAKIDGMDSFLYDATGTIDGEAYKGQL
                     FLVDTPTGIFKCNLYVKG"
     gene            complement(6451..7191)
                     /locus_tag="AC1PIV_001595"
     CDS             complement(6451..7191)
                     /locus_tag="AC1PIV_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HIP6612605.1"
                     /translation="MKKEFFVIGDVHGKFELLLDILKKWNEKRQQLIFLGDLIDRGEN
                     SKACLELVWSLVREKGAICLTGNHERMFLAWLRDPIDRYDHYRRNGGDTTINSLLGRP
                     LDAPVDGLVDANAVLEQYEDLIDFVKSCPYHLETEDYIFVHAGVDLTLPDWRETSNHD
                     KVWLRTPFHEAENTTGKMIVFGHTPVYNLYQTKLRISQIWTSPDGKMGIDGGAVYGGV
                     LHGIVLDGTGLVQDYIVGAVNPRKEIED"
     gene            complement(7257..8606)
                     /locus_tag="AC1PIV_001596"
     CDS             complement(7257..8606)
                     /locus_tag="AC1PIV_001596"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HIP6612606.1"
                     /translation="MTHITFDYSKVLGQFVGAQEVEYMQPQVTLADQMLRQGTGPGSD
                     FIGWLDLPENYDKEEFARIKEAAAKIQNESEVLVVIGIGGSYLGAKAAIDFLSNAFVN
                     LQTREERKAPQILYAGNSISSSYLADLVDYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDKAKGAVKVEADANGWETFVVPDDVGGRFSVLTAVGLL
                     PIAAAGADIDALMEGANAARTTFTSDKIAENQAYQYAAVRNILYRKGYVTEILANYEP
                     SLQYFSEWWKQLAGESEGKDQKGINPTSANFSTDLHSLGQFIQEGNRNIFETVVRVDK
                     PRKNILIPEMAEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGGVPNMFVTLPQQDEF
                     TLGYTFYFFELAIAISGYLNAINPFDQPGVEAYKKNMFALLGKPGFEELGAELNARL"
BASE COUNT         2487 a         2060 c         1737 g         2333 t
ORIGIN      
        1 ccaactagaa aggatttttt atgaccaaac aaaccattgc catcttggga cccggttcat
       61 ggggcaccgc cctaggacaa gttctcaacg acaacggtca tactgtccgt atttggggaa
      121 atgtccctga acaaatcgac gaaatcaata aagaacatac aaataagcgc tatttcaagg
      181 atgttatcct agatgaaaac atcaaaggat ataaggattt gagtgaagcc ttggacggtg
      241 ttgacgcggt tcttttcgtt gtgccaacca aggtaacacg cctagttgcc aagcaagtcg
      301 cacaagctct caaacacaag gtagttgtca tgcacgcttc aaaaggctta gagcctgata
      361 gtcacaagcg cttgtctgag gtactggagg aagaaattcc tgctgaactc cgttctgaaa
      421 tcgtcgtggt ttcagggcca agtcatgcag aagagactat cgtccgtgat ttgaccttga
      481 tttctgcagc ttcaaaagac ttggaaacag ccagctacgt ccaaaatctt ttcagcaacc
      541 actacttccg actttacaca aataatgatg tcatcggcgt agaaacagca ggtgccctta
      601 aaaatattat tgctgtcggt gccggcgctt tacacggact tggttatggt gataatgcca
      661 aggcagctat tatcgctcgc ggtttgacag aaatcacacg tctaggcgtt gctatgggcg
      721 caaatcctct gacttacagc ggtctttctg gtgttggtga tttaattgtt accggtacat
      781 ctgtccactc ccgcaactgg agagctggag atcagctcgg tcgcggtgaa aaactcgaag
      841 atgtagaacg caatatgggg atggtgattg aaggtatttc aacaactaaa gcagcctatg
      901 aattggcaca ggaattgggc gtttacatgc ctattactca agccatctac aaggtcatct
      961 accaaggtgc aggtattgaa gatgccatca aagaaatcat gacgggtgaa ttccgacatg
     1021 aaaatgaatg gcattgattt ttattaaaca gaaaaaataa aattaaaagg attacatact
     1081 tatgaaaaaa gttagaaaag ccgttatccc tgcagcaggt ttgggaacac gtttcttgcc
     1141 tgccactaag gctcttgcca aagaaatgtt gccgattgtt gataaaccaa ctattcaatt
     1201 tatcgttgaa gaagctctac gatctggtat cgaagatatt ttggtggtca ctggtaaatc
     1261 aaaacgttct atcgaagacc actttgattc aaactttgaa ttggaataca acctcaaaga
     1321 aaaaggcaaa aatgatttgt tgaaacttgt tgatgagaca acaggcattc gactacactt
     1381 cattcgtcaa agccatccac gtggacttgg tgatgccgtt cttcaagcta aagcatttgt
     1441 cgggaacgag ccatttgttg tcatgctggg cgatgacctc atggacatca cagatacaaa
     1501 agctgtccca ttgactaagc aactcatgaa cgactatgaa aaaacacatg cttcaaccat
     1561 tgctgttatg cccgttcctc atgaagaagt ttctgcatac ggtgttatcg ctccacaagg
     1621 tgaaggtgtc aacggtctct atagtgtgga aacctttgtg gaaaaaccaa aaccagaaga
     1681 cgctccttct gaccttgcta ttatcggacg ctacttactc actcctgaaa tctttgagat
     1741 tttagaaaac caaaaaccag gtgccgggaa cgagattcaa ttgacagatg ctatcgatac
     1801 actcaataaa acacaacgcg tgtttgctcg tgaattcaaa ggcaaccgtt acgatgttgg
     1861 ggataagttc ggtttcatga aaacttctat cgactacgcc ctccaacacc ctcaagtaaa
     1921 agatgatttg aaacaatact tgatcgatct tggtaaaaaa ttagatacaa agaaaaacta
     1981 gcaagcgcta gttttttctt atgtcaaata aaatatccct aataataggg cgatcagacc
     2041 cagatagcca atgaaactga aaaaaatctg ttttcctgta aagagatctt tttccacaag
     2101 aggtggaagg aacatcacga ccaagcaacc tccaacagct cctccaatat gtcctgccat
     2161 actaatggtt ggattaaaaa gtcctaagac caagttcaat cctaaaagga ccatgtagcg
     2221 ttgaccaaga acctgtagat aagggctgcg actaaatttc ctcaaaagtg ccatagccgc
     2281 aaaaagacca aagagcgagg tcgatgcacc tgcaccaact acatctggtg taaaaaagag
     2341 aacaaaaaga ttgcccatta tcccagacaa gagatagagg agaaagaagc gccttgagcc
     2401 aaacagtcct tctaattgat aacccaaacc aagcaaagta atgctgttaa agataaaatg
     2461 ctcccaacca atgtggacaa agatggggga aatcaaccgc cacaactgag tcggatcata
     2521 ccgcacaact tgaccataca tgccaccaaa ttcaaaaatt gtataggctg tagtggtctg
     2581 cccaaatcga aatacttgta tcaaaagaaa aacaagagcc gtgactgcca acaagccatt
     2641 ggtcacagga tagcgcttat caaaaaagtt cttcaaaaat caacaactcc ttcactggaa
     2701 tatcaaaaac atctggttcg aaatcataga cttgaaagtc tgccaaggtc gataccgtct
     2761 ccccctgata atctgctagg tagcgatcat aaaaaccacc accatagccc actcgaaaac
     2821 ccgcttgatt ccaagctaaa ccaggcacat ggagcaactt aaccacagac ttatccacag
     2881 gttgtgaata aataccaggt tcccaaactc caaacctaga tttcaccaaa tcatcaggat
     2941 tatattctac aaaatccata cgtccttgtg aataggtctt agggatgaaa atctgcttgc
     3001 cgtccttttg agcctgttca atcaggtaag aagtgtcaaa ctcatggggc atggaaaggt
     3061 aggtcccaag cgactttgca ccctgataag tatcagaagc aaggaggcgt tccgttaact
     3121 gctgactcca tcttgctcgc tgactactag tcagatcttt caaactctgc aagacctctt
     3181 gccgaatgct ctttttatcc acagaaactc ctttcttttc agaaaaagac tggaaaacca
     3241 gtctagtttg ctttcatttt caaaaaatca ctcaacttat ccacagcaaa gggaagcact
     3301 tcctccttgg gactaaggcg aggattgtgg aggggataag gcgtatccac acccagccag
     3361 aacataacac ccggcacctt gttgagcagg tagccgaagt cctcacccgt catggcaggt
     3421 ggacagtcaa tcatctccac tccgtcaatg ccatcaaagt aggtcatgag ttcatccgcc
     3481 aactgaggat tattttccac aggtagataa ccgctaggat tgagctcgat ttccaagtct
     3541 actccaaagg acagggcgat tccctctgcc acttcccgca cccgcttttg caccagaaga
     3601 ctcatgttct gggtcaaagc ccgaatggtg ccgtgcaaaa aagctgtttc agcaataaca
     3661 ttattggtcg tgcccgcgtg catggagccg aaggtgacca ccgctccctc aatcggatca
     3721 acgttacggc tgaccaccga ctgcacctga gtcacaaagt agctggctgc caccaaggcg
     3781 tcatttgcgg tatagggaaa tgctgcgtgc ccaccctttc ctgtaaatcg tatcttgact
     3841 tcacaggtcc cagcaaagag ggtcgcacgg ttggtggcca tttgaccaac tttgaggtcc
     3901 ggtcggacat ggagcccata aaattcatct ggtaaccaat ccccgaaagc tcccgcttca
     3961 tacataagca tgccacctgc tagattttcc tccgcaggct gaaacaagaa gagaagatta
     4021 tttctcggct gctgctctgc cattttctcc aaaagcccca aggcaatggt catgtggaaa
     4081 tcatgtccgc aggcgtgcat cctgtctggg tggagggact tgaagtccag gcccgtctcc
     4141 tccacgatcg gcagaccgtc aatatccgcc cgccagccaa tcgttttctc tggagcagag
     4201 cctgtcagat agaccagaat ccctgtcttc caagtgcgga cttgggcaaa agaacagtct
     4261 tgaagtaaac cttcaatagt ttccataaga aaggcgtggg tcttgaactc ctccatgccc
     4321 agctctggaa tctggtggag ggcccggcgt gtcgcaatca aatctagcat agctacctct
     4381 tagagtgtcc gcaaagcctc ttccaaggct gttttttgtt gggtttgagc gtcgatttcc
     4441 ttgatgatgc gggctggcac acctgccacc actacgtttt caggaacatc ttgagtcaca
     4501 atggcacccg ccgccactac agaaccgcta ccgatttgca cgccctcgat aacaacggca
     4561 ttggcaccga ccaaaacgtt gtcgccgaca cgaactggct cggcagaagc tggctcgatg
     4621 acacctgcaa ggaccgcacc tgcaccgatg tggctgtttt taccaacggt cgcacggccg
     4681 cccaaaatcg cacccatatc aatcatggta cctggaccga tttccgcacc gatgttaatc
     4741 accgcgccca tcatgataac ggcattatcg ccaatggtca cttgatcgcg gataatggca
     4801 cctggctcga tacgggcatt gatattacgc ttgtccagca aaggcacagc cgaattgcgg
     4861 ccgtcttgct ccaccacata gtctacattt tcagtcaagt ttgccaagag tggctcgaca
     4921 tccttccagt caccgaagag gacattgcca agctttgtca cttcagcagg aacagctcct
     4981 gccaattctc cttcaaaggt cactttaaca gttgtcttct tcacagcatt accgataaaa
     5041 gcaatgattt cttgcgcagt cattttttgt gcagtcataa tgtttccaat ctaaaaataa
     5101 tattttttct attatatcaa aattttctga aaatttggga agaaatgcaa aaaaatgaaa
     5161 aagggagtgg gaaagaactc gattaggtca aaaaagagtt cgtcttccca ccctcgcaca
     5221 gttgattagg ccagatttgg agtgcaaaac acgaacaaat ctgccaatca accactgcgc
     5281 tgagatgttg atacgaactc tgagaagtga tcctgggctt tttgcccagc ctcctaaata
     5341 ctatagaact ctctatcctc ctaaagcagc tgacatttgc tctatctgct gttgcaaacc
     5401 atctctatac tctttcaaga atgtaataat ctctgctctt ccaacaattg cagcatttcc
     5461 taatggacca tattgttttt tctgttgctc aacagattgt gataccgtat cacgcacaga
     5521 ctggtacata gtggcatcac ccaatccata ctggctgacc atattttcat agttcgtaat
     5581 atattcattc acaatgaatt catacatctt catataatcg ctataagttt ttatactttc
     5641 aattgttgca tctgagctat ctgtcggatt aaattctgaa actgtagcag tactttctga
     5701 acttgttggg gtttccgtag ttttagagga agattctact acctcatcac taatatctac
     5761 gctatttaag atctgttcaa actcttgttt cctagtggaa gaatagtcat cctttgacat
     5821 ataaattaca tttaaaaatc cctgttggag tgtcgactaa aaagagttga cctttatatg
     5881 cttcgccatc tatcgtacct gtcgcatcat aaaggaagct gtccatccca tcaatcttag
     5941 ctgagctttc gttagctggt atcacttttc ctgactgttc catccccttc agatattggg
     6001 agcgaacagt tgcatcttta actgattcct ctaagggcaa ccaatatgcc attgccaatg
     6061 atgaatcatc gggataaaaa tataaggtat cactcgtatc cccttcttta ctcttccatg
     6121 attcatttat gctgatagcc acttctgaca attggtaagt tttgtatctt atagagcttg
     6181 tacttacctg ttctgtcgaa gattggccac cgctagagct cgtaaggttc ttaatcagac
     6241 caatcgcaaa caatccaacc aacacaataa accaaattcg cttgtaaaat ggtttctttt
     6301 gcacatagac attcccatgt tcatctctaa ttttcttcgc catataatcc tccaaaaaat
     6361 tgtgtacaac accattatat atatatatgc gttgtcaagt agaaaaacaa aaaaattaga
     6421 agttttacct cctaattttc atgtattatc ttaatcttca atttcttttc tgggattgac
     6481 agctcctacg atgtaatcct gtaccaagcc tgtaccatcc agcacgatcc catgcaaaac
     6541 tccgccgtaa acagctccac cgtcaatccc cattttccca tctggactgg tccagatttg
     6601 gctaatgcgg agttttgttt gataaaggtt ataaacagga gtatgcccaa agacaatcat
     6661 cttccctgtg gtattttcgg cctcatggaa aggggtgcgt aaccaaacct tatcatgatt
     6721 gctggtttca cgccagtctg gtaaggtcaa gtccacacca gcatggacaa agatataatc
     6781 ttccgtttcc agatgatagg gacaagattt gacgaaatca atcaggtcct catattgttc
     6841 caacactgca ttggcatcca ccaatccatc tacaggagca tccaagggcc gaccaagaag
     6901 ggagttaatc gtcgtatcgc caccatttcg ccgatagtgg tcatagcggt caatcggatc
     6961 acgcaaccag gctagaaaca ttcgctcgtg gttacccgtc agacaaattg cccccttttc
     7021 ccgcaccaag ctccagacca actccaaaca ggctttggaa ttttctccgc gatcaatcaa
     7081 atcacctagg aagatcaact gttgtcgctt ctcgttccat ttcttcaaaa tatcgagtag
     7141 cagttcaaac tttccatgga catcgccgat tacaaaaaat tcttttttca tagactctat
     7201 tctaccacat ttaataagca aagaaaaact gaccgtttcc gatcagtttg gttttcttac
     7261 aaacgtgcgt tcaattctgc accgagttct tcaaatcctg gttttccaag aagagcgaac
     7321 atgtttttct tgtaggcttc tacacctggt tggtcaaatg ggttgattgc attgaggtaa
     7381 ccagagatcg caattgccaa ctcgaagaag tagaaggtgt aaccaagtgt gaactcatct
     7441 tgttgcggaa gagtgacaaa catgtttggt acgccaccat ctgtgtgggc aagaagtacg
     7501 ccgtccgttg cttttttgtt tacaaagtca acgtcttttc cttgcaagta gccaagaccg
     7561 tcaaggtctt ctgccatttc aggaatcaag atattttttc ttggtttatc aacacgaact
     7621 actgtttcaa agatattgcg gtttccttct tggataaatt gtccaagtga gtgcaagtct
     7681 gttgagaagt tagcggatgt tgggttgata cctttttggt ccttaccttc tgactcgccc
     7741 gccaattgtt tccaccactc gctgaagtat tggagtgatg gctcgtagtt agccaagatt
     7801 tctgttacat agccttttct gtaaaggatg ttacggacag ctgcatattg gtatgcttgg
     7861 ttttcagcaa tcttatcaga tgtaaatgtc gtgcgggctg cgtttgcacc ttccataagg
     7921 gcatcaatgt ctgcaccagc tgccgcgatt ggcaaaagac caactgcagt caagactgag
     7981 aaacgaccgc cgacatcatc tggaactaca aaagtttccc aaccatttgc gtccgcttca
     8041 accttaactg caccttttgc cttgtcagtt gtcgcataga tacgcttgtt ggcttcttct
     8101 tgaccgtatt tcttgacaag taattctttg aagacgcgga aggcaatagc aggttcagtt
     8161 gttgtacctg attttgaaat cacgttaact gagaaatcct tatcagcaac ataatccacc
     8221 aagtcagcaa gatagcttga tgagatagag tttccagcgt aaaggatttg tggagctttg
     8281 cgctcttcac gtgtttgcaa gtttacaaag gcattgctca agaaatcaat agctgcttta
     8341 gcaccaaggt aagaaccacc gataccgata actaccaaaa cttcactttc attttggatt
     8401 ttagctgctg cttccttgat acgagcaaac tcttctttgt cgtagttttc tggcaaatcc
     8461 aaccagccga taaagtcgct accaggacct gttccttgac ggagcatttg gtctgcaagg
     8521 gtaacttgtg gttgcatgta ttctacttct tgagctccaa cgaattggcc caagactttt
     8581 gaataatcaa atgtaatatg tgtcatgttt ttcctcc
//
LOCUS       DBNFCO010000073         8121 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.073, whole genome shotgun sequence.
ACCESSION   DBNFCO010000073 DBNFCO010000000
VERSION     DBNFCO010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 8121)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8121)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8121
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.073"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            67..450
                     /gene="gloA"
                     /locus_tag="AC1PIV_001597"
                     /gene_synonym="lguL"
     CDS             67..450
                     /gene="gloA"
                     /locus_tag="AC1PIV_001597"
                     /gene_synonym="lguL"
                     /EC_number="4.4.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HIP6612607.1"
                     /translation="MASKKMLHACLRVENLEASQKFYEEAFGFKETRRKDYPEHKFTL
                     VYLALEGDDFEIELTYNYDHGPYIVGDGFSHLALSSDDLEGDNAKHKELGYPTTDIKG
                     LPGSPGRYYFVTDPDGYRVEVIRAD"
     gene            742..2139
                     /locus_tag="AC1PIV_001598"
     CDS             742..2139
                     /locus_tag="AC1PIV_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HIP6612608.1"
                     /translation="MKKVSFWLGINIALLGIMVSLAVWLFAGLQERQVSQFIEEKQQT
                     ILAKGKGKIQEGNIDTTHVVAALPTDDAGHVLGPVESRMISYVQRRFGHKKPAGKIQK
                     LVFVSSIEGKTNFKNVTAREIQAEHYKVDNLQIKKQDKLPSERVLLTQDNELFTLEDL
                     LPNLSSAASIIVDHLREALLAQGMKETDVEAIVKKFETLDLNAISFSYGDSQLTLQLP
                     DGYGINQLVLPISDLYPVVKSDYLVDADKVGYDEYMAAQVVDKKHLRQVALTFDDGPN
                     PNTTPVVLDLLKKYNAKATFFVVGKAVVGNEAILRRMVAEGHVIANHTWNHPNLVTIS
                     GEQVQREIQDTQAAITEATGIVPTMVRPPYGSVNQAVVNQMGLPSIYWSVNSKDWKSR
                     NPQAILKEIKEQTCPGSIILMHDIHQSTVDSLESVLQYLTGEGYNMVTVTDLLASPLN
                     PQLIYYSQELSGPAQ"
     gene            complement(2206..3288)
                     /locus_tag="AC1PIV_001599"
     CDS             complement(2206..3288)
                     /locus_tag="AC1PIV_001599"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HIP6612609.1"
                     /translation="MKSKFPSSWTDQLTLLGFEDFTPIQVQAFEPIANGKSLLAISPT
                     GTGKTLAYLWPSLLALTPKKAQQLLILAPNTELAGQIFEVCKTWSETIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNINTIVLDEFDQLFSDSQYQFV
                     EKIINYVPRDHQLIYMSATAKFDRQKIAEDIESIDLSEQKLDNIQHCYMMVDKRERLE
                     TLRKFANIPDFRALAFFNSLSDLGASEDKLLYNGVNAVSLVSDVNVKFRKVIIERFKN
                     HELNLLLATDMVARGIDIDNLECVLNFEVPFDQEAYTHRSGRTGRMGKEGLVITLVSS
                     PSELKQLKKYASVQEVILKNQELYKI"
     gene            complement(3278..4264)
                     /locus_tag="AC1PIV_001600"
                     /pseudo
     CDS             complement(3278..4264)
                     /locus_tag="AC1PIV_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936219.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family protein"
     gene            4347..4976
                     /gene="udk"
                     /locus_tag="AC1PIV_001601"
     CDS             4347..4976
                     /gene="udk"
                     /locus_tag="AC1PIV_001601"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004849 - uridine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HIP6612610.1"
                     /translation="MTQKPIIIGVTGGSGGGKTSVSRAILDNFPNARISMIEHDSYYK
                     NQSHLTFEERILTNYDHPLAFDTDLMIYHISELLAGRSVDIPIYDYTQHTRSEKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDIRIIRRIKRDMEERGRSLDSIIEQ
                     YTSVVKPMYHQFIEPTKRYADIVIPEGVSNVVAIDLINTKVESILRERG"
     gene            4978..5517
                     /locus_tag="AC1PIV_001602"
     CDS             4978..5517
                     /locus_tag="AC1PIV_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HIP6612611.1"
                     /translation="MPKQRILPHIILGIMGASGQMVTGKQITDYVQRDLGEFWQVAHS
                     QVYPELKRMTKEELITCHAVPGNEKEKQYAMTATGRQILDEWLSIPNEETPQQKNLFS
                     IKMFFIREKDDPRIPGLLQSQIELVTKHLKHLDSRKVELFSTKESIQDNYGHYLILTR
                     AIERNRAQLKWLEDTLAEM"
     gene            5605..5874
                     /locus_tag="AC1PIV_001603"
     CDS             5605..5874
                     /locus_tag="AC1PIV_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HIP6612612.1"
                     /translation="MSIKQMVSMALVVWNLLVFITYGMDKGKARKNAYRISEKTLLLM
                     SYFGGGLGAWAGGTHFRHKTQKKYFQLAWAIGVLIDAVIMYWMWK"
     gene            5939..6436
                     /locus_tag="AC1PIV_001604"
     CDS             5939..6436
                     /locus_tag="AC1PIV_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HIP6612613.1"
                     /translation="MTKQEKISNYQLLLAQLEALLDGETNALANLSNASALLNQALPN
                     SVFTGFYLYDGSELILGPFQGGVSCVHIALGKGVCGEVAAKRQTILVDDVRLHDNYIS
                     CDATALSEIVVPMVKNDQLLGVLDLDSRLVADYDTIDQDYLEKFVALLVEKTDWNFAM
                     FGEKR"
     gene            6436..8103
                     /gene="dnaX"
                     /locus_tag="AC1PIV_001605"
     CDS             6436..8103
                     /gene="dnaX"
                     /locus_tag="AC1PIV_001605"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HIP6612614.1"
                     /translation="MYQALYRKYRSQTFGEMVGQEVVATTLKQAIEQGKISHAYLFSG
                     PRGTGKTSAAKIFAKAMNCPNQVGGEPCNDCYICQAITEGSLEDVIEIDAASNNGVDE
                     IRDIRDKSTYAPSLATYKVYIIDEVHMLSTGAFNALLKTLEEPTENVVFILATTELHK
                     IPATILSRVQRFEFKSIKVTDIQEHLAAILTKEGLIFDEQALTIIARRAEGGMRDALS
                     ILDQALSLSQDQQVTLEIAEEITGSISLRALDDYVASLRQGDSVTALQHLQTLFDQGK
                     SMSRFATDLLHYLRDVLIVQTGGEDTHLTTVFSENLALEQARIFTMIEMVTRGLADIK
                     SSPQPKIYAEMMTIRLAEDSSPSEAMAELPADLLGQLASLQQQVADLQKQLSQLSSQP
                     SAVKPVSRKPQAPKKYRLDTSKVHAILQEAMENPTLARENLTRLQNAWGEIIESLSGA
                     DRALLVGSQPVAANENHAILAFDSPLNAEQTMKRDNLNTMFGNILSKAAGFSPQILAI
                     AQEDWVSIRAEFSAKAKGQKTQEIEKEASPVPEEFGFLADTVEIRND"
BASE COUNT         2404 a         1510 c         1874 g         2333 t
ORIGIN      
        1 tgaatatcgg atttttcata gagagtatgg tatactggtg gtattaaatg gtaggaggaa
       61 tttattatgg caagtaaaaa aatgttgcac gcttgtttgc gtgttgagaa cttagaagca
      121 tctcaaaaat tttatgaaga agcatttgga tttaaggaaa cccgtcgcaa ggactatcca
      181 gagcacaagt ttaccttggt ttacttagca cttgaaggag atgactttga gattgaattg
      241 acctacaatt atgatcatgg tccctatatc gtaggcgacg gtttctcgca tctagctctt
      301 tcttcagatg atttagaagg ggacaatgcg aaacataagg agctgggcta tccaacgaca
      361 gacatcaagg gattgccagg aagtccaggt cgttattatt ttgtgacaga tccagatggc
      421 taccgtgtgg aagtcattcg tgcagattaa tttagaaaag attgcctagg cagtcttttt
      481 cttttcaaaa aaaaatcaga aaatggcagg aggggggaat taggaagcaa atcaattatt
      541 tatactcaat gaaaatcaaa agtagtctag gaaacgaagc cgaagatgga actggagttc
      601 atcaaggaaa gttgacaacg gataattttg attttcgaag agtattacct aatcttttta
      661 tgagttttta tagaactgtc ttgacaagag cctttaaatg atttagcata gtttatatat
      721 gttttgaatg ggaggttgga gatgaaaaaa gttagttttt ggttgggaat caacatcgcc
      781 ttgctcggca taatggtaag tttggctgta tggttatttg caggacttca agaaagacag
      841 gttagtcagt ttattgagga aaaacaacaa accatcctcg ctaaaggcaa gggcaaaatt
      901 caagagggaa atattgatac gacccatgtt gtggctgcct tacctacaga tgatgcaggt
      961 catgtcttag gacctgtaga aagtcgaatg atttcctatg ttcaaagacg ctttggtcat
     1021 aaaaaaccag caggaaaaat tcaaaaactg gtctttgttt catcaataga gggaaaaaca
     1081 aattttaaaa atgtaacagc tcgtgaaatt caagcggagc actataaagt agacaacttg
     1141 caaattaaaa agcaggataa actcccgtct gagcgtgtgt tattgacgca ggacaatgaa
     1201 ttgtttactc tagaagattt attacctaat ttatcctctg cagcaagtat tattgttgat
     1261 catctaagag aagccttact tgctcaagga atgaaagaga ctgatgtaga agcgattgtc
     1321 aaaaaatttg aaacactaga cttaaatgct atttccttta gttatggaga cagccaatta
     1381 accttacaat taccagatgg ttacggcatc aaccagttgg ttctaccaat ttcagatttg
     1441 tacccagtag tgaagagtga ttatctagta gatgctgata aggttggcta tgatgagtat
     1501 atggctgcac aagttgtgga taagaaacat ttgagacagg tcgctctaac ctttgatgat
     1561 ggacccaatc cgaacacaac accggtagtt ttagatttac tgaaaaaata taatgccaaa
     1621 gcaactttct ttgttgttgg taaggctgta gttgggaatg aagctattct ccgtagaatg
     1681 gtagcagaag ggcacgtcat cgccaaccat acgtggaatc atcccaatct agtcactatt
     1741 tctggggagc aagtacagag agaaattcaa gatacacagg cagctattac tgaagctaca
     1801 ggtattgtac caacaatggt ccgtcctcct tatggttctg ttaaccaggc cgttgtcaat
     1861 cagatgggac ttccatcgat ttattggtcg gtcaattcta aagattggaa gagtcgcaat
     1921 ccccaagcca ttttgaaaga aataaaagaa cagacttgtc caggaagtat tatcctaatg
     1981 catgatattc atcagtcaac agttgatagc ctcgagtctg tattgcaata tttaacaggt
     2041 gagggctaca atatggttac tgtaacagac ttactcgcta gtcctctcaa tcctcaatta
     2101 atctattatt cacaagaatt atccggccca gcccagtaag aatgataaaa ggcttagaat
     2161 catgttagta gaaacactgg ttctaagcct tttgtatatt gttcattata ttttgtagag
     2221 ctcttgattc ttgagaatga cttcttggac ggaggcatac tttttcaatt gttttagttc
     2281 gctaggacta gatactagag tgatgacaag accttccttg cccatgcgtc cagtacgtcc
     2341 agaacgatga gtgtaggctt cttggtcaaa aggaacttca aagttgagga cacattctaa
     2401 gttatcaata tcaataccac gtgcgaccat atctgtagca agtagaagat tgagttcgtg
     2461 attcttgaaa cgttcgatga tgaccttgcg gaattttacg ttgacatcag aaaccaatga
     2521 aactgcattc acaccattat agagtagttt atcttcgctt gcaccaaggt ctgataggct
     2581 gttaaaaaat gcaagagcac gaaaatcagg gatattggca aacttacgta gagtttccaa
     2641 acgttcacgc ttatctacca tcatatagca atgttggata ttatccaatt tctgctcaga
     2701 taaatcaatg ctttcaatgt cttcagcaat tttttgacgg tcaaatttag ctgttgcact
     2761 catgtagatt aactggtggt cacgaggcac atagttgata atcttttcga caaactgata
     2821 ttgagaatcg gagaacagct gatcaaactc atctaggacg atggtgttga tattcatcat
     2881 cttgattttt ttcaatttaa tcaactcgaa aatacgacca ggtgttccaa tcaggatttc
     2941 tggtcctttt tttagtcgct caatctggcg tttttgactg gaaccagaca agaatagttg
     3001 agcagtcaac ccaattgtct ccgaccaagt cttacaaacc tcaaatattt gaccagccag
     3061 ctctgtattg ggtgcgagga tgagcaattg ttgggctttt ttaggagtta gggctaatag
     3121 gctaggccag aggtaggcaa gggtttttcc tgtgcctgtt gggctgatag ctagaaggga
     3181 cttgccgttt gcaataggct caaaggcctg gacttggata ggagtaaagt cctcaaagcc
     3241 aagtagggta agctggtccg tccagctgga gggaaattta gatttcattg ttatccgcct
     3301 taaagattat tcctgcgtct tgacgcatgg tgtaaagtgt ttgatggacg ctttctgcca
     3361 cagccagcca ctggtccaca agcttgcggt tttgttgctt gattgcctgt gcaatttcta
     3421 acacttcttc gagcatagga tgctgggccg cttggattgg taaaacaatt tgctctccgt
     3481 catgttttgt gaaaatagcg gagctgatat gctggcatgc gttgagtgtt agtgttccat
     3541 catttgtata gatttcgctc gctagattgc ttgtaatatt ttttcatgct tgaatgtgga
     3601 cgatatagtt gtcataaatg agttgtcccg aaccgtttaa gtcaatacca aaaggtagct
     3661 gttgtgctac atagcgggcc gttctgggag ttcccaaaat gccgatagcg gcgtagagcg
     3721 tatagacacc aaaatccatg agagcaccac cggaaaaatc agttgaaaag atatttggca
     3781 tttgcccagc taacaattca ggcatcttag aagaatactt ggcataccca aatgaaccac
     3841 ctaaaatcgt tttatccgtc aaaaattcac ggataatggc ttgagcttgt tcgtgatagt
     3901 ttcgagcagc ctcaaagagg aaaacattat tttcttgggc aacgcgacgc aattgttcta
     3961 attcctgagg tgtagaaacc atgggtttct caacaatagc atgtttacca gcagctagaa
     4021 cagcttttgc ctgttcaaag tgcagggcat ttggactggc aatatagaca acatcaatgg
     4081 gagcagaaag aaattttacc cattctgtgt ataaatcgac tccttcatac tgctctgaaa
     4141 aggcagcagc agtttctagt ctacgggaga aaacagcctg tagctgataa tgtccactta
     4201 aatgggctgc ctctataaaa cgatgagaga tgtctgaggt gccaacaata ccaaaattaa
     4261 gcataaattc tcatttcttt tgtgttatcc ttttcattat accatgtttc atggtaaaat
     4321 agtattgaaa atagaaggag atgatgatga ctcagaaacc cattattatt ggcgtaaccg
     4381 gcggatctgg gggtggcaag acaagtgtgt cacgtgccat tctggataat ttcccaaatg
     4441 ctcgtatatc tatgattgaa cacgattctt attataagaa tcagtctcac ctgacctttg
     4501 aagaacggat actgaccaat tatgaccatc cactggcttt tgatacggat ttgatgattt
     4561 atcatatcag tgagctatta gcaggacgtt cagtggatat tccgatttat gattacactc
     4621 agcacacacg ttcagagaag acctatcgtc aggaaccaca agatgtattt attgtggaag
     4681 gtattttagt attggaagac aaacggttgc gggatttaat ggatattaag atattcgttg
     4741 atactgatga cgatattcgt atcattcgcc gcattaagag agacatggaa gagcgtggcc
     4801 gtagcttaga tagtatcatt gagcagtaca cctcggtggt gaaaccaatg tatcaccagt
     4861 ttatcgagcc aaccaagcgc tatgcagata tcgtcattcc tgaaggcgtc agcaacgttg
     4921 tagccatcga cttgattaac accaaggtgg agagtatatt aagagagcgt ggttaagatg
     4981 ccgaagcaaa gaatattacc tcatatcata ttagggatta tgggtgctag cggtcaaatg
     5041 gtaactggca agcagattac cgactatgtt caacgtgatt taggcgaatt ttggcaggtt
     5101 gcccatagcc aagtctatcc agaattaaaa cgtatgacca aggaagaatt gattacttgt
     5161 catgcagtac ctggaaatga aaaggaaaag cagtatgcga tgacggctac tggtcgtcag
     5221 attttagacg aatggctatc cattccaaat gaagaaacgc ctcagcaaaa aaacttgttt
     5281 tcaatcaaga tgttttttat ccgtgaaaag gatgacccac ggattcctgg tttgttgcag
     5341 agtcaaattg aactagtcac caagcactta aaacacctag acagtcgtaa agttgagctg
     5401 ttctcaacca aggaaagtat ccaagacaat tatggacact atttgatttt gacacgggct
     5461 attgaacgca accgtgccca gctcaaatgg ttagaggata cactggcaga aatgtaacga
     5521 ttcggatttc cgaatcgttt ttccttgtgt cctgttttgg attatgttag agtaagaaga
     5581 aatgtgactt aattggagga atgtatgtca atcaaacaga tggttagtat ggcgctagta
     5641 gtttggaatt tacttgtctt cattacctat ggtatggata aagggaaggc aagaaaaaac
     5701 gcctatcgga tttcagaaaa gaccttatta ctcatgtcct attttggtgg cgggctgggt
     5761 gcctgggcag gtggaaccca ttttcggcat aagacacaga aaaagtattt tcaactagcc
     5821 tgggctatag gggtattgat tgatgcagtg attatgtact ggatgtggaa ataggcgcaa
     5881 gcctttttct ttatcgctcg gactataaaa gtcggcttaa ctatgctata atgttcctat
     5941 gacaaaacaa gaaaaaattt caaactatca attattgttg gctcaattgg aagctcttct
     6001 tgatggggaa accaatgctt tagccaatct atcaaatgct tctgctttgc tcaatcaagc
     6061 tctaccaaac tctgtcttta caggatttta cttgtatgat ggtagtgaat tgattttggg
     6121 gccttttcag gggggcgttt cctgtgttca tattgcactt ggaaagggtg tctgcggtga
     6181 ggttgcagct aagcgccaga ctattctcgt agacgatgtt cgtctacatg ataactatat
     6241 ttcctgcgat gcgacagccc tatcagaaat cgttgtgcca atggtgaaaa acgaccagtt
     6301 gctgggcgtt ttggacttgg attcgagatt ggtagctgat tatgatacga ttgaccaaga
     6361 ctatctggaa aagttcgttg ctctcttggt tgagaagacg gactggaatt ttgctatgtt
     6421 tggagaaaaa cgctaatgta ccaagcttta tataggaagt accgaagcca gacctttggg
     6481 gagatggtgg ggcaggaggt ggttgcgacc acactcaaac aggccattga acaagggaaa
     6541 atcagtcatg cctatctctt ttcaggtcct cgtggtacgg gtaagacatc ggcagctaag
     6601 atttttgcca aggccatgaa ctgtcctaat caggttggag gcgagccttg taacgattgt
     6661 tatatctgtc aggccattac ggaaggtagc ctggaagatg tgattgagat tgatgcggct
     6721 tccaacaatg gtgtggatga gattcgtgat attcgtgata aatcgaccta tgcacctagt
     6781 cttgcgacct ataaggtcta tatcatcgac gaggttcaca tgctgtctac tggagccttc
     6841 aacgccctct tgaagacctt ggaagaaccg actgaaaatg tggtctttat tctagcaacg
     6901 acggaattgc acaagattcc tgctaccatt ctgtcaaggg tgcaacgatt tgaatttaag
     6961 tccatcaagg tgacggacat tcaggagcac ttggctgcaa ttttaaccaa ggaagggcta
     7021 atctttgacg aacaggctct gacaatcatt gcgcgtcggg cagaaggagg gatgcgggat
     7081 gccctatcta ttttggatca ggctctcagc cttagtcagg accagcaagt gaccttggaa
     7141 attgctgagg aaattacggg ttctatcagc ttgcgtgcct tggatgacta tgtggcaagt
     7201 ctgcgtcaag gggatagtgt cacagctctc cagcatctac aaaccttgtt tgaccaagga
     7261 aagagtatga gccgttttgc gacagatctt ttgcactatt tgagagatgt ccttatcgtg
     7321 cagacgggtg gagaggatac gcatttaaca acagtttttt cagaaaatct agctcttgag
     7381 caggcacgga tttttaccat gatagagatg gtgaccaggg gtttggcgga catcaagtcc
     7441 agtcctcaac ccaagattta cgctgaaatg atgaccattc gtttggctga agatagttct
     7501 ccttcggagg caatggcaga gctgccagct gatttactgg ggcaactagc cagtctgcaa
     7561 caacaagttg cggatttaca gaaacaacta agtcaattat ctagtcaacc aagtgctgtt
     7621 aagccagttt cacgcaagcc gcaggctccg aagaagtacc gattggatac cagcaaggtt
     7681 catgctattt tgcaggaagc tatggaaaat ccaaccttgg cgcgtgaaaa tttgactcgc
     7741 ttgcagaatg cttggggaga aattatcgag agtctgtcag gtgcagatcg tgccttgttg
     7801 gttggttccc agccagttgc tgccaatgaa aatcatgcga ttctagcctt tgattctccg
     7861 cttaatgctg aacagacgat gaagcgtgac aatctcaata ccatgtttgg aaatattctc
     7921 agcaaggcag ctggtttttc cccacagatt ttagctattg ctcaggaaga ttgggtaagt
     7981 attcgtgctg aattttcggc gaaagcaaaa gggcaaaaga cacaggaaat cgaaaaagaa
     8041 gccagtccag tcccagaaga atttggcttt ctcgcagata cagttgagat tagaaatgat
     8101 tagaaaatat cagtcctaag a
//
LOCUS       DBNFCO010000074         8049 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.074, whole genome shotgun sequence.
ACCESSION   DBNFCO010000074 DBNFCO010000000
VERSION     DBNFCO010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 8049)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8049)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8049
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.074"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(<1..621)
                     /locus_tag="AC1PIV_001606"
     CDS             complement(<1..621)
                     /locus_tag="AC1PIV_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612615.1"
                     /translation="MALANADEWAGEGRGVTKIEVYAMSELSKVTIRISGKAMDESKG
                     YELKYLLKSLDSFSKLSEKTYLHMISEDRLKKSESGNFALYIDNFQHGSFLADLVIVM
                     NSYALPLLEHGQTIWGAITTVYDFIKTISSAKEEGKSVSIENVGDGSIAVAVSDSSSV
                     GDITINNYLYPEYVRELSPKLAPSFSKLVHSIDENIDEISFNSSDGR"
     gene            complement(573..1832)
                     /locus_tag="AC1PIV_001607"
     CDS             complement(573..1832)
                     /locus_tag="AC1PIV_001607"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HIP6612616.1"
                     /translation="MSEVRWQIKSLSELGRFSRGKSKHRPRNDKKLFTNGTYPLIQTG
                     DIKNSNLYVTKNSDYYNEFGLSQSKLWKQGTLCITIAANIAETAILSYPMCFPDSVVG
                     FNAHKNESSELFVYYVFELIKKEIQKTSSGSIQDNINIDYLTKLKLKVPNKDYQDRIV
                     NLLSTIDKKILINNQINEELEAMAKTLYDYWFVQFDFPDENGKPYKSSGGKMVYNDQL
                     KREIPEGWGVKQLGEICEFRNGINYEKSETGDTLSKIVNVRNISNSSTFVTTHDLDSI
                     TLDRRRIESYLVTDRTILITRSGIPGATRIVSDIPVNTIYSGFIIGATVANLNLFYYV
                     FYHLKNIEMLMSNQSAGTIMKNISQTTLSEIRIVIPNKEIQKVFSNEVRSLLDVIENN
                     LKQNQELTQLRDWLLPMLMNGQVKVEE"
     gene            complement(1825..3466)
                     /locus_tag="AC1PIV_001608"
                     /pseudo
     CDS             complement(1825..3466)
                     /locus_tag="AC1PIV_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638904.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
     gene            complement(3471..6524)
                     /locus_tag="AC1PIV_001609"
     CDS             complement(3471..6524)
                     /locus_tag="AC1PIV_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HIP6612617.1"
                     /translation="MIRKEHNEFTRVQLPAALHLTRLGYDYLSATSEDIKNRDHSTNI
                     LLSIFKRQFLTFNNYASEADFEQEFENIRLELEQDDLGRSFFNRIHADSGYTYINWDN
                     MEENTFHIALEVTCQNGEEEFRPDITVFINGLPLSYIEVKQPDAIRDGKTGIHSEKER
                     AKLRFENKKFRRFNNITQLIAFSDNLPYDDSQGQQLQGSYYCTNASSGTKFNSFKEEQ
                     EGQVQSSLSSLTEEMIDLVLTDVNRFALKSQVEFRTNLDPASPCNSFLTSLYQKERLF
                     FMLRYGLVYVEERDEHDQIQLQKHAMRYPQYFATKAIERGLEEGMKKGVIWHTQGSGK
                     TALAFFNIRYLRDFYAKRGVVPQFYFVVDRLDLADQAYKEFSKRGLKVKRINKPSELN
                     QIQDQHHVSVVNIQKFKESSDLTDHSGYDLNRQNIYFIDEAHRSYNEKGSYLPNLYNA
                     DKEAVKIALTGTPLIATKADGKTKETAVTTRDIFGDYIHKYYYNQSIADGFTLRLMRE
                     DIETSYKETLQAVHEEIQKGSIEKKEIFAHPRYVSPMLDFILDDFTRAREILFGDQSI
                     GGMVVCDSSEQARELHKQLEDRRKAGLTSFTSTLILHDAGDKEYKKEEVDKFKDGLID
                     FVIVYSMLLTGFDAPRLKRLYLGRKIKAHNLLQTLTRVNRPYKDYAFGYVIDFADISK
                     EFDKTNKAYLEELNREYQAALTEEDGDNPFGTIFVSPEEVQEQLASSNRVLMNYPTDN
                     LEFFGRAIDEVKDRKELIALRKSLETIRQYYNMARLHGYHDIVKQVNIGEIASLLNML
                     SRRLLTLNLLEKPDSFSSQQLLNLAMSETSFSFTKIKEEELRLAANDLDDIRRRVANG
                     INLRRDEKDPEWVSLYEEFQRILNKHMTQEVEGYSLSTIKETKQAYQSLFDSVEDYKT
                     RMNRLAMNFGGDTMSARAFKHITQSTVVSDFPAIYQVLKGAKPLIDYQIGLNQGILEN
                     EAYLVAQIRQLARKEMMKTEVGKQLKRVDYDKLIRSLMEVYEGEY"
     gene            complement(6617..7933)
                     /locus_tag="AC1PIV_001610"
     CDS             complement(6617..7933)
                     /locus_tag="AC1PIV_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002943607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016668 - oxidoreductase activity, acting
                     on a sulfur group of donors, NAD(P) as acceptor [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HIP6612618.1"
                     /translation="MEQYDLVVIGFGKAGKTLAGKLSAAGKKVALVEENPVMFGGTCI
                     NIGCIPTKTLLVAADKNWTFEQVMEQKETVTTRLRNKNEAVLKGSGANLYQGHARFVA
                     DKVVEVSAGEESIQLTAETIVINTGAKSRVLPIPGLLDTAHVYDSTGIQNLETRPNKL
                     AIIGGGNIGLEFAGLYSKLGSQVMVYEASSAILPREEEGVAQLAKEYMEEAGMTFVLG
                     AKIEQVAAAGEQVAVTVNGETAIFDAVLYATGRVPNTADLGLENTAIELLENGAVKVD
                     DYRETTVPGVYAVGDVNGGPQFTYTSLDDFRIVFGKLTGTGTYSLSQRKSIPTSVFIT
                     PVLSRVGLTEKEAKEAGYDYIANELLVANMPRAHVNNDLKGIFKVIVDKESKLVLGAT
                     LFGRNSEELINLIAMAIDNKIPYTYFKTQIFTHPTMAENLNDVFNF"
BASE COUNT         2273 a         1731 c         1508 g         2537 t
ORIGIN      
        1 cctaccgtca ctagaattaa atgagatttc atcaatattt tcatcaatag aatgaaccaa
       61 tttggagaaa gagggagcaa gttttggaga taattctctt acatattctg gatatagata
      121 gttatttatt gtaatatctc caacacttga actgtcactt accgctacgg ctattgaacc
      181 atcaccgaca ttctcaatac ttaccgattt accttcttct ttggcagagg aaattgtttt
      241 tataaaatca taaacagttg tgatagctcc ccaaatagtt tgaccatgtt caagtaaagg
      301 aagggcatat gaattcatta caattactaa atcagctaag aaagaaccat gttgaaaatt
      361 gtcaatatat agtgcaaaat taccactttc actctttttg agcctatctt cgcttatcat
      421 atgtaaatac gtcttttctg ataacttgga aaaactatcc aaagatttta acaaatattt
      481 aagttcgtaa cctttagatt catccattgc tttaccagaa attctgatcg tgaccttgct
      541 taattcactc atagcataaa cctctatttt cgttactcct ctaccttcac ctgcccattc
      601 atcagcattg gcaagagcca atcacggagt tgggtcagtt cttggttttg ttttaaatta
      661 ttttcaatta catctaaaag acttctgact tcatttgaaa ataccttctg aatttcttta
      721 tttgggatca caatgcgaat ttctgaaagt gtagtttgag aaatattttt cattatagtt
      781 cccgcagatt gattagacat gagcatttca atattcttta gatgataaaa tacataataa
      841 aatagattca aattggcaac agttgcacca ataataaaac ctgaataaat tgtgttaact
      901 ggaatatcag agactatcct agtcgcccca ggaattccac tgcgagttat cagaattgtt
      961 ctatctgtaa caagatagct ttcaatacgt cttctatcta aagtaattga gtccaaatca
     1021 tgagtagtaa caaaagtact agaatttgaa atgttccgta cgtttacaat ttttgaaagc
     1081 gtatcccctg tctcagattt ttcataattg attccatttc taaattcaca tatctcaccc
     1141 aactgcttca ctccccaccc ttctgggatt tcccgtttga gttggtcgtt atagaccatt
     1201 ttaccaccag aggacttgta gggcttacca ttttcatcag ggaaatcaaa ctgcacaaac
     1261 caataatcat aaagcgtctt ggccatagcc tccaactcct cgttgatttg gttattaatt
     1321 aagatttttt tatcaatagt tgacaataag ttgacaattc tatcttgata atctttgttg
     1381 ggaaccttta attttaattt tgttaagtag tcgatattaa tattatcttg gatactacca
     1441 ctagatgtct tctgaatttc tttttttatt aattcaaaaa cataataaac aaacaactca
     1501 cttgattcat ttttatgtgc attaaaacca acaacactat caggaaaaca cattgggtaa
     1561 gatagaatcg ctgtttcagc aatatttgct gctattgtaa tacaaagagt cccttgcttc
     1621 catagcttac tttgtgacaa accaaattcg ttataataat cactattctt tgttacataa
     1681 agatttgaat ttttaatatc acctgtctgg attagcggat aggttccatt agtaaataat
     1741 tttttatcat ttcttggacg atgtttagat tttccccttg aaaatcttcc cagttcagac
     1801 aaactcttta tttgccatct tacctcactc atacctcacc cccctcacct gctccgctat
     1861 ttccttttcc aattcatgcg attgggcaaa gaggttagct aggcggtctt ggtagccctg
     1921 cattttttct tcaaattctt ctgggctaat atcaacgtag tcaatcttga tgtcaaagta
     1981 ctgacctgca ctgagggagt agttcttatc cttaatctct tcatagctaa ccttgacaga
     2041 gaagtcttcg acaacttctt tgttaataaa ggtctgaatg atttggcttt cttcatcagg
     2101 gctaaggact gtcttttggt tcttgccttc cttgaccttg gtgccaagat tagaagcgtc
     2161 aatcaagacc acatcgtcct tattcttctt atcgataaag agaatggaca cattggtgcc
     2221 tgtggtcgca aagatattgg acggcatgga cacaacgcct gccaacatct tttcatcgac
     2281 aaggtgctga cggattttct tgtcaatacc tgactgggcg gtgataaagc ccgtcggcaa
     2341 gacaatagct gcctgcccgt cttccttcaa actatggata atatgctgga taaagagttg
     2401 gtaaatagcc atactctctt ttttcttgtt gggaatcttt ggcacacctg caaagaaacg
     2461 ttcactgcta tttggcaggc tttctacctg atctcgccac tcagaaaaat ctaatttgaa
     2521 aggaggattg gacacgatat agtccatctt ctccacatga cgattgttga gaatggtatt
     2581 tccctgtacg atattgtgaa tggaatgctg caagccattg agaatcaagt tgagacgcaa
     2641 gagattggag gatttctgag aaatatcctg actgtaaacg ctggtacggt cggtaccaat
     2701 ctgactggcc agattcatca ccaatctgac tggccagatt catcaagaga gtccccgaac
     2761 cagcagaagg atcatagatt ttgacattac ttggttggtc attgcccacc aaaatggccg
     2821 cgatgatttt ggcaacagag tgaggtgtgt agtattccgc atactttcca ccaccgtctt
     2881 tgttatagtc cttaatcatg tactcaaaca aggtggagaa aaagtcaaag ccctgtgaaa
     2941 aaatctgctg atcaaactta acacgcgcca agagattgat aatagaagct gccacttcat
     3001 ttcgcttgct ggcatctgaa atcgtatccg taatcaagcg ttgatcaaag aggcgaatat
     3061 ctgttccacc gtccgtatgg acagagaaaa tagcattgtt gtcaatagca atctgattga
     3121 gagtctgttc aaaaatctca gcaaaatctg cttggttctg ttgacggtgt aggctttcaa
     3181 tcagctgttc aggttttaga tgagcagttt tagtcccaat atcatctaaa aaccagtcat
     3241 aatcttcttc agacaagtcc aaaagacctt gatagtcata acgattgtca acgatcaagg
     3301 cttcatacaa aaacttgtca tttaagaact tgtaaaggaa ggactgggtc agaagtttgt
     3361 actcccccgc ttctcctcca agtcctgcat gggtaaagac ggcttttagg tcatcaacca
     3421 agccttgtac ttgactttgc acctgcacga tataatgttc ttccatttgt ttaatattct
     3481 ccttcataga cttccattag ggaacgaatc aacttatcat aatcgactcg tttgagttgc
     3541 ttccctactt ctgttttcat catttcttta cgggccagtt gcctgatctg cgctaccaaa
     3601 taggcttcgt tttccagaat gccttgattg agcccgattt gataatcaat cagaggtttg
     3661 gcacctttta gcacctgata aatagctggg aagtcactga caactgttga ttgggtaatg
     3721 tgcttaaagg cacgggcaga catggtatct ccaccaaagt tcatggccaa gcgattcatt
     3781 cttgttttat agtcttctac tgaatcgaat aaactttgat aggcttgttt ggtttcttta
     3841 atggttgaga gactatatcc ttctacttcc tgtgtcatgt gcttgtttag gatgcgttga
     3901 aactcttcat aaagacttac ccattcagga tctttttcat ctctccgtag attgatacca
     3961 ttggccacac ggcgtcggat atcgtccaaa tcattggctg ccagtcgtag ttcctcttcc
     4021 tttatcttgg taaaactaaa gctagtctca gacatggcta gattcagtag ttgctgacta
     4081 gaaaaactat ctggtttttc taacaagttc aaagtcaaga ggcggcggga cagcatattt
     4141 aaaaggctag caatttctcc tatattgacc tgtttgacaa tatcgtggta accatgcaaa
     4201 cgtgccatgt tgtagtactg acgaatggtt tcaagagatt ttcggagggc gattaactct
     4261 ttcctatcct tgacttcatc gatggctctt ccgaaaaatt ctaagttatc tgtcggatag
     4321 ttcattagaa ctcggttaga gctcgctagc tgttcctgga cttcttctgg ggacacaaaa
     4381 atagttccaa aaggattatc tccgtcttct tctgtcaaag ctgcctggta ttcccgattg
     4441 agttcttcca gataggcttt attggtcttg tcaaattcct tggaaatgtc cgcaaaatca
     4501 atgacatagc caaaagcata atccttgtac ggacggttga cacgggttaa ggtctgcaag
     4561 agattatggg ccttgatttt ccgtccaaga tagagccgtt tcagccttgg tgcatcaaaa
     4621 ccagtcaaga gcatggagta gacgatgaca aagtctatca gaccgtcctt gaatttatcc
     4681 acttcttctt tcttgtattc cttatcccca gcatcatgta aaatcaaggt tgaagtgaat
     4741 gatgtaagcc ctgcttttcg acggtcttct aactgtttgt gtaattctcg ggcttgttct
     4801 gaagaatcac agaccaccat tccaccgata gactggtcgc caaataagat ctctcgtgct
     4861 cttgtaaaat catcaagaat aaagtctagc attggagaga cataacgggg gtgggcaaaa
     4921 atttctttct tttcaatgga gcctttttga atctcttcgt gtacagcttg tagagtttcc
     4981 ttgtaagaag tttcaatatc ttccctcatc aaccgtaggg taaaaccgtc agcaatggat
     5041 tgattatagt agtatttgtg gatatagtcc ccaaagatat cacgagtcgt cacagctgtt
     5101 tccttggttt taccgtcagc ctttgtcgca atcaaaggcg ttcctgtcag tgcaatttta
     5161 acagcttctt tatcagcatt atatagattt ggcagatagg aacctttttc attgtaagaa
     5221 cggtgagcct catcaatgaa gtagatattt tgccgattca agtcatagcc tgaatgatct
     5281 gtcaaatcag aggattcttt gaatttttgg atgttgacaa cagaaacatg gtgctggtct
     5341 tgaatctgat ttaactcgct tggtttgtta attcgtttga ctttgagacc acgcttgcta
     5401 aattccttat aggcttgatc agccaaatcc aatcggtcta ccacaaagta aaactgcggg
     5461 acaacacctc ttttagcata aaagtctcgt aagtatcgga tattgaaaaa tgctagagcg
     5521 gtttttccag aaccttgtgt atgccaaata acacctttct tcatcccttc ttccaatcct
     5581 cgctcaattg ccttggtcgc aaaatattga ggatagcgca tggcgtgttt ttgtagttga
     5641 atctggtcat gctcatctcg ttcttccaca tagactagac catagcggag catgaaaaag
     5701 agccgttctt tctgataaag ggaagttaaa aaggaattgc aaggacttgc aggatccaag
     5761 ttggttcgga attcaacttg cgacttgagg gcaaaacgat tgacatctgt gagaaccaaa
     5821 tcaatcatct cttctgttaa gctagacagg ctagactgta cttgtccctc ctgctcttcc
     5881 ttgaaagagt tgaacttggt accagatgaa gcattggtgc agtaataaga accttgcaac
     5941 tgttgtcctt ggctatcatc atagggaaga ttgtctgaaa aagcaatcaa ctgtgtgata
     6001 ttgttaaacc gtctgaattt tttattttca aagcggagct tggcacgttc tttttcagag
     6061 tgaattcctg tttttccatc acgaatagca tctggttgct tgacttcgat ataactgaga
     6121 gggagaccgt tgataaaaac ggtgatatca ggccggaact cttcctcacc attttgacag
     6181 gtgacttcta aggctatatg gaaggtattc tcttccatat tatcccaatt gatataggtg
     6241 tagccagaat ctgcatgaat ccgattaaaa aaacttcgtc ctaaatcatc ttgttctaat
     6301 tccaggcgaa tgttttcaaa ttcttgttca aaatcagctt cacttgcgta attattgaat
     6361 gttaaaaact gtcgcttaaa aattgataga aggatattgg ttgaatggtc tctgtttttt
     6421 atgtcttcac ttgtagccga aagatagtca tatccaagcc gagtcaaatg caaagcagct
     6481 ggcaactgaa ctcttgtaaa ctcattgtgt tcctttctta tcatacaact ctcctagtct
     6541 tttcttatca atcattatac catatttgca agtgctgacc gacaaaaaac cgccctattg
     6601 gacggttatt acactattaa aaattaaaga catcgttcaa attctcagcc atagtcggat
     6661 gggtgaagat ttgtgttttg aagtaggtat aaggaatctt attgtcaatc gccatagcaa
     6721 tcaagttaat cagctcctct gaattgcgac caaagagagt cgcccccaga acaagcttac
     6781 tttccttatc cacgataacc ttgaaaatgc ctttgaggtc attattgaca tgggcacgtg
     6841 gcatattggc gacaagcaat tcgttggcaa tgtagtcgta acctgcttcc ttggcttcct
     6901 tctcggtcag accaacacga gaaagcacag gcgtgataaa gacgctggtc ggaatagact
     6961 tacgttggct caagctataa gttccagtcc cagtcaactt gccgaaaacg atacggaagt
     7021 cgtctaggga tgtgtaagtg aattgtggac cgccattgac atctcccacc gcatagacac
     7081 ctggaacagt cgtttcgcgg tagtcatcca ccttaacagc accattttcc aaaagctcaa
     7141 tcgccgtatt ttccaagccc aagtcagcag tgttcggcac ccgacctgtc gcatagagga
     7201 cagcgtcgaa aattgctgtt tcgccattga ccgtcacagc aacttgctcg cccgcagctg
     7261 cgacttgctc gattttcgca cccaagacaa aggtcatgcc agcttcttcc atatactcct
     7321 tggctagctg agcgactcct tcctcttctc ttggtaaaat agcagagctg gcttcatata
     7381 ccatcacctg gctgccgagt ttgctgtaaa gtccagcaaa ttccaatcca atgttaccac
     7441 caccgataat tgccaacttg ttaggacgag tttccaagtt ctgaatgcct gtactatcat
     7501 aaacgtgagc tgtatccaac aaacctggaa ttggaagcac gcgcgactta gcacctgtgt
     7561 tgatgacaat agtttccgca gtcagttgaa tcgactcttc accggccgac acttcaacga
     7621 ctttgtccgc aacaaaacgc gcgtgacctt gataaagatt agcaccactg cctttcaaga
     7681 ctgcctcgtt tttgtttcgc agacgagtgg tgactgtttc cttttgctcc attacctgct
     7741 caaaagtcca gtttttatct gctgctacca agagggtctt ggttggaata cagccaatat
     7801 tgatacaagt cccgccaaac ataacaggat tttcctcaac caaggcaacc ttttttccag
     7861 ctgctgacag cttaccagcc aaggtcttac cagcctttcc aaaaccaatg actactaaat
     7921 catattgttc cataaaatac tcctttattt tttcaacatt agtctatcaa aaaagaaaat
     7981 ttttggcaca attctgctac ggcctattat ggagtcctag ttgcaggaaa aaacattaca
     8041 ataactgag
//
LOCUS       DBNFCO010000075         7901 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.075, whole genome shotgun sequence.
ACCESSION   DBNFCO010000075 DBNFCO010000000
VERSION     DBNFCO010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 7901)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7901)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7901
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.075"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            213..965
                     /locus_tag="AC1PIV_001611"
     CDS             213..965
                     /locus_tag="AC1PIV_001611"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIP6612619.1"
                     /translation="MLLEINHLEKVYRTRFSKEETRALQDVDFKVEEGEFIAIMGESG
                     SGKTTLLNILATLDKPTRGSVILNNQDITKIKESKLADFRLRNLGFVFQDFNLLDTLS
                     IQDNIFLPLVLARESYQEMEKRLEVLAPKLRIQDLLKKRPFELSGGQKQRVAIARSLI
                     TQPQIVLADEPTAALDYRNSEDLLNLFEEINRDGQTILMVTHSANAASHAKRVLFIKD
                     GRIFHQLYKADKSNQDFAKEISLNMSALLGGE"
     gene            966..2936
                     /locus_tag="AC1PIV_001612"
     CDS             966..2936
                     /locus_tag="AC1PIV_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIP6612620.1"
                     /translation="MFYLKLAGQNIRKSMGVFAPFVLASLVLFTLICSMFLIMLSPVM
                     KTMGSGAISIGLGVIILTIFSVIMEIYSFNFLMKQRAREFGLYNMLGMNKKKVALIAS
                     LELMMIFLLVVVLGSVLAGVFANVLYLIFVNITHYSDLHFGIEPLAFVMTAFLFAGFF
                     FLLELLAIRTIGKTSPLILFRASEKGEREPKGNVLLAALGVFSLGMGYYLSLSSKAEG
                     LAVIYRFFIAVLFVIAGTYLFYISFMTWYLKARRKNKRYFYTPEHFITTSQMIFRMKQ
                     HATGLANITLLAVMAFVTIATTTSLYTGMSSMTGALYPKETSITYKVSDRSQGEMAFQ
                     QSVLSHFPEKADDSLSYLTYQAGLVYDGGEEIVISPKNISNPDFSKMAFTYFITQDDF
                     RKLGNDLPELAANQVVFMRPSEKPSLKKLVLGDQSFENVANLDKAIFPDITNTLNAAV
                     MVVSDDTVLNAVREYYESNNPQGYLVSLDYRVFTDLTDEEVLSLGEQSGEIYEILDEN
                     GEYLGNVMQRTDFNNLLMGFTGGFLFTGFLLGISFLLGAALIIYYKQYSEGHEDKKSY
                     KILQEVGMSQKAVKKTINSQTLTVFFMPLVMATLHFVIALIMLKQMLLSFGVTSSLMI
                     YTVSGITLLAVTLIYFVIYKWTSRTYYRIIER"
     gene            3028..3279
                     /gene="relB"
                     /locus_tag="AC1PIV_001613"
     CDS             3028..3279
                     /gene="relB"
                     /locus_tag="AC1PIV_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002943256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HIP6612621.1"
                     /translation="MAAITLKVSEQDKLFMQAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADIALSEYEADLAKGIEPISWEEMLEELGLTDEDLL"
     gene            3263..3520
                     /locus_tag="AC1PIV_001614"
     CDS             3263..3520
                     /locus_tag="AC1PIV_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0004521 - RNA endonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE family
                     toxin"
                     /protein_id="HIP6612622.1"
                     /translation="MKTCYKLVPTSRFIKQLKKLDKFTQKQITNYLSSHVTDNPRQYG
                     KALTANRSGQWRYRIGNYRVIVNIEDDKLIVTSIKMRNGSI"
     gene            3559..4224
                     /locus_tag="AC1PIV_001615"
     CDS             3559..4224
                     /locus_tag="AC1PIV_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012961975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HIP6612623.1"
                     /translation="MKKEKIYIVEDDEMIVQLLKQHLGKSYQVESVQNFRAVSQEVAE
                     IKPDLVLMDINLPYYNGFYWTTEIRKTMTMPIIFISSSDDEMNAVMAMNMGGDDFVSK
                     PFSLGILDAKIGAFLRRVNQFSKSSELSIDQFQLSLDGRFSNESEQVQLSPTETKILS
                     ALLERQGQIVSKDELLEKLWENEEFIDQNTLNVNMTRLRKKVSEVGFERIHTVRGVGY
                     LIK"
     gene            4221..5162
                     /locus_tag="AC1PIV_001616"
     CDS             4221..5162
                     /locus_tag="AC1PIV_001616"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIP6612624.1"
                     /translation="MIAKFIREYRSFYFSYIVLATSFILLFFLYQLPTEFLQNALLLS
                     LTFLILLTVGLFWKFRNRMRALEDYVHEEALPLLNKPVDLAYLNLIEAEKEATREQLL
                     VYKSREEDLQAMVKMWSHQMKVPLAALSLMSQTDNLNQQDVNHQLLRLDNYMANLLNY
                     LKLTNHVSDFRFEQVEVREVVVDLVKKYRNQFLQKDISVIIDGNWLLKTDRKWLSFAL
                     SQIIDNALKYNKTGGKVAIELNGGISIFDTGIGILAEDLPRLFDEGFTGFNGREHQKA
                     TGFGLYLTKRVLNQLELAISVESQLEIGTTVSITKVQ"
     gene            5238..6746
                     /locus_tag="AC1PIV_001617"
     CDS             5238..6746
                     /locus_tag="AC1PIV_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HIP6612625.1"
                     /translation="MSHHHVLQNGSDIRGIAIATDEYAVNLTPQATQEVVRGLIHWLT
                     QKPELAQVYQKGQLTIGIGRDSRLSGPDLVAAFTEEAVCLGVQLIDFGMATTPALFMS
                     TQYPQFKCHAGVMITASHLPYYFNGIKIFSENGGAEHEDIDFILSHSEDLPASSLGSI
                     TSADLITPYAQDLVGKIRTACGGQEKPLTGLNIIVDAGNGAGGFFAEKVLAELGADTT
                     GSQFLDPDGTFPNHVPNPDNKEAMESIRQAVLKQGADLGIIFDTDVDRAALVTKSGEI
                     LNRNNLIAVLSQIVLAEHPGTSIVTNSPTTEHLKVFIESLGGKQIRYISGYRNVINRA
                     ILANQEGVDCQLAIETSGHAAFKENYFLDDGTYVAAKILMLLPKLQAEGKSLDDLIAQ
                     LKQPLETQEVRFKLEATDYRALGEQVIADLRQTSLEGFAFNPENEEGVRFDLTEPYGD
                     GWLLLRMSLHEPLLVLQVENDQTGHIPAVLRTLSAFLDQYPAVNQEKLKALI"
     gene            complement(6816..7886)
                     /gene="xerS"
                     /locus_tag="AC1PIV_001618"
     CDS             complement(6816..7886)
                     /gene="xerS"
                     /locus_tag="AC1PIV_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HIP6612626.1"
                     /translation="MRRELLLEKIDQLKEIMPWFVLEYYQSKLAVPYSFTTLYEYLKE
                     YRRFFEWLQDSDLVAVERIADIPLDVLEHLTKKDMEAFILYLRERPLLNANTTQNGVS
                     QTTINRTLSALSSLFKYLTEEVENEQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETMEFLDYVDKEYQVNLSKRALSSFQKNKERDLAILALLLASGVRLSEAVNLD
                     LRDVNLNMMIIEVTRKGGKRDSVNVAGFAKPYLEAYMGIRQQRYKAEKTDTAFFLSEY
                     RGLPNRIDASSIEKMVAKYSADFKIRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAN
                     TQVTDLYTHIVNDEQKNALDQL"
BASE COUNT         2204 a         1677 c         1773 g         2247 t
ORIGIN      
        1 tatttattac agtgaatatt gtgtttagtt ttatttttta tcagttaact atcaagaatt
       61 tggaaaatag taaataaaaa ccttttacaa tttcatgtat ttcttttata aagctgataa
      121 ttagaaactc aatttcatgg gatttagtac caaagaaaat tagctatact aaatcaagtt
      181 aattttgcta aagaaaacaa ttaggagtaa ctatgttatt agaaatcaat catttagaaa
      241 aagtttaccg cacgcgcttt tcaaaagagg aaactcgtgc cttgcaagat gtggatttta
      301 aggtagaaga gggcgagttt atcgctatca tgggggaaag tggttctggt aagacgactt
      361 tgctcaacat tctagcaacc ctggacaagc cgacgagggg ctctgttatc ttaaacaatc
      421 aagacatcac caaaatcaag gaaagcaagc tggcagattt ccgtttgcgt aatcttggct
      481 ttgtcttcca agattttaac ctcttggaca ccctgtccat ccaagacaat atctttttac
      541 ctctggtatt ggcacgtgag agctatcagg aaatggagaa acggttggaa gtattggcac
      601 caaaactacg gattcaagat ttgctgaaaa aacgtccctt tgaactttct ggtggacaaa
      661 agcagcgcgt ggctattgct cgtagtttga ttacccagcc acagattgtc ctagcggacg
      721 aaccgacggc tgccctagat tatcgcaatt cggaagactt gctgaatttg tttgaagaga
      781 ttaaccgtga cgggcaaact attctcatgg tgacccactc ggccaacgca gccagccacg
      841 ccaaacgtgt cttgtttatc aaagatggtc gtattttcca tcaactgtac aaggcagaca
      901 agagcaatca agactttgcc aaggagattt cactcaatat gtctgcactt ttagggggtg
      961 agtagatgtt ttacctcaaa cttgctgggc aaaatatccg aaaatccatg ggtgtttttg
     1021 ctcccttcgt tttagccagt ctggtcctct ttaccctgat ttgttccatg ttcttgatca
     1081 tgctgagtcc agttatgaag accatgggct ctggtgccat ttctatcggt cttggtgtga
     1141 ttattctgac cattttctcg gtcattatgg agatttatag ttttaatttc ctgatgaaac
     1201 aacgggcgag agaatttggt ctctataaca tgctggggat gaacaagaaa aaagtagcct
     1261 tgatagctag cctcgaattg atgatgattt tcttgctagt tgtggttctt ggttctgttt
     1321 tagctggtgt gtttgcaaat gttctctact tgatttttgt caatataaca cattatagtg
     1381 atttacattt tggaattgag cctctggcct ttgtcatgac tgcctttctc tttgctggtt
     1441 tcttctttct cttggaattg ctagccattc ggaccattgg caagaccagt ccgctgattt
     1501 tgttccgagc tagtgaaaaa ggagagagag agccgaaagg aaatgttctt ctagctgctc
     1561 ttggtgtttt tagtcttggg atgggctact acctatcgct ttcatcgaaa gcagaaggtc
     1621 tagctgttat ctatcggttc tttatcgctg tgctctttgt cattgcgggg acctatctgt
     1681 tctacatcag ttttatgact tggtatttga aggctcgtcg gaaaaacaag cggtatttct
     1741 atacgccaga gcatttcatt acgacatcgc agatgatttt tcggatgaag cagcacgcaa
     1801 cgggtttggc caatattacg ctacttgcgg tcatggcctt tgtgaccatt gcgaccacaa
     1861 cctcccttta tacaggtatg agcagtatga caggtgcact atatcccaag gaaacatcta
     1921 ttacctataa agtttcggat agaagtcaag gtgaaatggc cttccagcaa tcggtgctca
     1981 gccattttcc agaaaaagcc gatgacagtc tatcctatct gacctaccaa gctggtctgg
     2041 tatatgatgg tggcgaagag attgtcatta gcccaaaaaa tatttctaat ccagattttt
     2101 ctaaaatggc ctttacctac ttcatcaccc aagatgattt cagaaaattg gggaatgacc
     2161 tgccagagct tgctgccaat caagtggtct ttatgcgtcc gagcgaaaaa ccatcgctga
     2221 agaagcttgt tttgggcgat caatcctttg agaatgtagc caatcttgat aaggctattt
     2281 tcccagacat caccaatacg ctaaatgccg ccgttatggt agtcagtgat gacacagtgt
     2341 tgaatgctgt tcgtgagtat tacgaatcca ataatccgca aggctatctt gttagcctag
     2401 attatcgtgt ctttaccgac ttgactgatg aagaggtact ctctcttgga gagcaatctg
     2461 gtgaaatata cgaaattctc gatgaaaatg gagaatatct tggaaatgtt atgcaacgta
     2521 cggatttcaa caatttactg atgggcttta caggcggttt cctctttaca ggtttcttgc
     2581 tgggaattag tttcctactg ggtgcagcct tgattatcta ctataagcag tattcagaag
     2641 ggcatgagga caagaaatcc tacaagattc tacaagaagt aggcatgagc cagaaggctg
     2701 tcaagaaaac aattaactcc caaacactta cggtcttctt tatgcctttg gtcatggcga
     2761 ccctacactt tgtcatcgcc cttatcatgc tcaagcaaat gctactaagt tttggtgtta
     2821 cctcatcact aatgatttac acagtcagtg gcatcaccct actggcagtc actctgattt
     2881 actttgtcat ttacaagtgg actagtcgca cttattatcg cattattgaa cggtagcaga
     2941 agtctcgcct tgtgcgagat ttcttgcttt ttcagggaaa tggtgttaca atggtaatac
     3001 caaaggaata ctcgaagagg tgagaaaatg gcagctatta cattgaaagt ttctgagcag
     3061 gacaagctct ttatgcaggc tatggcaaag tttgaaggtg tcagtttgtc agaactcatt
     3121 cggactaaaa cccttgaagc tctcgaagat gaatatgatg cccgtgtggc agatatcgct
     3181 ctgtctgaat acgaggcaga cttggcgaaa ggcattgagc cgattagctg ggaggaaatg
     3241 ttggaagagt tggggttgac ggatgaagac ctgttataaa ctcgtaccga ccagtcgttt
     3301 tattaaacag ttgaaaaagt tggacaaatt tacccaaaaa cagattacca actacttgtc
     3361 cagtcatgtg actgacaacc ctagacaata cggaaaagcc ttgactgcta atcgttctgg
     3421 ccaatggcgc tatcgtatcg gcaattacag ggttatcgtt aatattgaag atgataaatt
     3481 gattgtgaca agcataaaaa tgagaaatgg aagtatataa gccaagacct gtgtcctggc
     3541 ttttgcagaa tgaagaagat gaaaaaagag aagatttata ttgttgaaga tgatgagatg
     3601 attgtccaac tcttgaagca gcatttggga aaatcttatc aggtagaaag tgtgcagaat
     3661 ttccgagctg tcagtcagga agttgcggaa atcaaaccag acttagtgct gatggacatt
     3721 aacttgccct attacaacgg tttttattgg acgacagaaa tccgtaaaac catgaccatg
     3781 cccattatct ttatctcttc tagcgatgat gagatgaatg cggtcatggc catgaacatg
     3841 ggtggcgatg attttgtctc caagccattt tctctaggaa ttttggatgc caaaatcgga
     3901 gccttcctgc gtcgggttaa tcaattcagc aaatcgagcg aattgtctat cgatcagttc
     3961 cagcttagtt tggacgggcg attttcaaac gaatcggaac aggttcagct ttcacctact
     4021 gaaaccaaga ttttatccgc cttactagaa agacaagggc agattgtcag caaggatgaa
     4081 ctcttggaaa aactctggga aaatgaagaa tttatcgacc agaatacgct caatgtaaac
     4141 atgaccagac tgcgtaagaa ggtgagcgaa gtcgggtttg aacgaattca taccgttcgt
     4201 ggcgtggggt acttgatcaa atgatagcaa aatttatccg cgaataccgg agtttttact
     4261 tctcctacat tgttctggct actagtttta tcttgctctt ctttctctat caactgccca
     4321 ccgaattcct gcaaaacgct ctgctattgt ccctaacctt cttaatcctt ctaactgtag
     4381 ggcttttctg gaagtttcgc aaccgcatga gagccttgga agactatgtc catgaagaag
     4441 ctctgcccct gcttaataag cctgtggact tggcctatct caacttgatt gaggcagaga
     4501 aggaggcgac acgggagcag cttttggtct ataagtcacg agaagaagac ctgcaagcta
     4561 tggtcaaaat gtggtcccac caaatgaaag tgcctttggc tgccctgtct ttgatgagcc
     4621 agactgacaa tctcaaccag caggatgtca atcaccagct cttacgcttg gataattaca
     4681 tggccaatct cctcaactac ctcaagctga ccaaccatgt cagtgatttt cgttttgagc
     4741 aggtggaagt aagagaagtg gtggtggatt tggtcaaaaa ataccgcaat cagttcttgc
     4801 aaaaggacat ttcagtgatt atcgatggaa attggctact gaaaaccgac agaaagtggc
     4861 ttagttttgc cctatcacag attatcgaca acgccctcaa gtacaataag actggtggaa
     4921 aggtggccat tgaattgaat ggaggaattt ccattttcga tacgggaatt gggattctgg
     4981 cagaagacct tcctcgcctg tttgacgagg gatttacagg ttttaatgga cgagaacacc
     5041 aaaaagcgac aggatttgga ttgtatctga ccaagcgggt cttgaatcag ttggaactag
     5101 ctatttccgt ggaaagtcaa ctggaaattg ggacaactgt aagcattaca aaagtacagt
     5161 agaagctgtg cttttttcat tttgaaaccg cttcgaaaat atgatatact aaatttagtt
     5221 tgaattagga ggttactatg tcccatcatc acgtcttgca aaatggatca gatattcgtg
     5281 gaattgctat cgctacagac gaatatgctg tcaatctcac tccacaagcc acccaggaag
     5341 tagttcgcgg acttattcat tggctaactc agaagccgga actggcgcag gtctatcaaa
     5401 aaggccaatt gaccatcggt atcggtcgag acagccgcct cagcggtcca gatttggtcg
     5461 cagcctttac agaagaagcc gtttgtctgg gcgttcagct gattgacttt ggcatggcca
     5521 ccacgccagc tctcttcatg agcacccagt atccgcagtt caagtgccac gctggtgtca
     5581 tgatcactgc cagccacctg ccctattact tcaacggcat taagattttt tcggaaaatg
     5641 gcggagcaga acatgaagat attgacttca tcctctcgca tagtgaagac ttgccagctt
     5701 cttcccttgg aagtatcacc agtgcagacc tgattacgcc ttatgcccaa gatctggttg
     5761 gtaaaattcg taccgcctgt ggtggacaag aaaaaccact gacaggtctt aatatcatcg
     5821 tcgatgctgg aaatggtgcg ggaggattct ttgctgagaa agtgttggca gaattgggag
     5881 cagataccac tggttcacaa ttcctagacc cagacggcac cttcccaaac catgttccaa
     5941 acccagataa caaggaagct atggaaagca ttcgtcaggc tgtcttgaag caaggtgcag
     6001 acctaggcat tatctttgat accgacgttg accgtgccgc cctggtcacc aagtcaggag
     6061 aaattctcaa tcgtaacaac ctgattgccg ttctcagcca gattgtccta gctgaacatc
     6121 caggaaccag cattgtgacc aattccccaa cgactgaaca ccttaaggtc tttatagaaa
     6181 gtctgggagg caaacaaatt cgctatattt caggctaccg taatgtcata aaccgtgcta
     6241 ttttagccaa tcaagaagga gttgattgcc agttggctat cgaaacatct ggacatgctg
     6301 cctttaagga aaattacttc ctcgatgacg gaacgtatgt agcggctaag attctcatgc
     6361 tcttacccaa actgcaagcg gaaggcaagt ccttggacga cttgattgcc cagctcaagc
     6421 aacccttgga aacccaagaa gtgcggttca aactggaagc cacagactat cgagcgcttg
     6481 gtgaacaggt cattgctgac ctccgccaaa ccagcctcga aggctttgct tttaacccag
     6541 aaaacgaaga aggagtgcgg tttgacctga ctgagcctta tggtgacggc tggctcttgc
     6601 tccgtatgag cctccacgag ccgctcttgg tcttgcaggt ggagaatgac cagactggac
     6661 acatacctgc cgttttacga actctctcag cctttttgga ccagtaccca gcagtcaatc
     6721 aggaaaaatt gaaagcattg atttagattt aagagaaaaa ggggtaagtt ttcgcttact
     6781 ccttaattta tttacataat ttatattacg tgatatcaca actgatccag agcatttttc
     6841 tgttcatcgt tgacgatatg ggtgtagaga tcggtgacct gggtattggc atggcccagc
     6901 tgatgactga ctagaacttg cgacttggtg gcgtcgtaga gacgagttgc caatgtgtga
     6961 cggagtttgt ggggggttac gcgtatcttg aagtccgcag agtacttggc aaccattttt
     7021 tcaatagaag aagcatcgat acggttaggc agaccacggt attcggacag gaagaaggct
     7081 gtatccgttt tttcagcctt gtagcgttgc tgacggatgc ccatgtaggc ttctaagtag
     7141 ggcttagcaa acccagccac attgaccgag tcccgtttac cacccttacg agttacttcg
     7201 ataatcatca tattgaggtt tacatctcga agatccaaat tcaccgcttc tgacagacgg
     7261 acgccagaag ccaagagaag cgccagaatc gccaaatccc gctccttatt tttctggaag
     7321 gaggagaggg cacgtttaga gagattgact tggtattcct tgtccacata gtccaagaac
     7381 tccatcgttt catcgcccaa aaagagcttt tgcttgatgt tctccgcccg cgctgccaag
     7441 gtttccttct tcttcttagt agataccttt ttcatgacat tgcggtagaa gtagggctcg
     7501 ccctgctcat tctccacttc ttcggttaaa tacttgaaga gactagaaag ggccgagagg
     7561 gtacggttaa tggtggtctg cgacacacca ttctgcgtgg tattggcgtt cagcaaggga
     7621 cgctcccgca gataaagaat gaaagcttcc atatcttttt ttgtcagatg ttccagaaca
     7681 tccagcggaa tgtcagcaat ccgttcaaca gccaccaaat ccgaatcctg taaccattca
     7741 aaaaaacgac ggtattcttt caagtattca tataaggtag taaaactgta aggcacagcc
     7801 aattttgact gataatattc cagaacaaac caaggcataa tttcttttag ttgatcaatt
     7861 ttttccaata ataactcgcg tctcatcatt ttctcctgat t
//
LOCUS       DBNFCO010000076         7841 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.076, whole genome shotgun sequence.
ACCESSION   DBNFCO010000076 DBNFCO010000000
VERSION     DBNFCO010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 7841)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7841)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7841
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.076"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(60..821)
                     /locus_tag="AC1PIV_001619"
     CDS             complement(60..821)
                     /locus_tag="AC1PIV_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HIP6612627.1"
                     /translation="MSNQLENAKNLYLRGIRDGEIKEVHENYMGASYTQHSTGVPDEK
                     EGFAAFFEDFFKRNPKREINIVRAIEDGNFVFVHVHQKLNDGAAEWVTADIFRSDENG
                     CIVEHWDVIDAYPKTIGQTDPIYADFELTDLDKTEDNKKIVRRFLVDVLQNGKIEKFD
                     DYVAADLIQHNQEIAQGGVAYKDYLVESQVNYDFVFKVMGQGDYVVAYSKVWIAGQDY
                     AHFDIYRLKDGKIVEHWDNKEVMPDKKDLTNLGKF"
     gene            complement(831..2342)
                     /locus_tag="AC1PIV_001620"
     CDS             complement(831..2342)
                     /locus_tag="AC1PIV_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HIP6612628.1"
                     /translation="MNLFETFIERKDEWGIALFEHLRISLLALIIAIAIAVPLGLILS
                     SKKRLTEWSLQITGIFQTIPSLALLGLFIPFMGIGTLPAVVALVIYAIFPILQGTLTG
                     LGEIDPSLEEAATAFGMNKWEKLKKFKLALAMPILMSGIRTASIMIIGTATLAALVGA
                     GGLGSFILLGIDRNDSALILIGAVSSAVLAVLFGYGIRLLQDKKPKTILLALLVTLFT
                     VGASYVPMLNFSTKQLVIAGKLGAEPEILINMYKLLIEDQTDIKVEIKPNFGKTSFLY
                     EALKSGSIDIYPEYTGTITSTLLKNSPMDLSTNPEEVYTYAKEAILEQDGLMYLAPMA
                     FQNTYALAVTEDYAQKNGLEKISDLAKVQQTAVAGFSLEFNDREDGNIGLKNLYNLQL
                     NVKTMEPALRYEAIKSGNVQIIEAYSTDSKVVTYKLKILEDDKQLFPPYQAAPLLSKE
                     TLEQYPELEQVLGVLAGNISTEEMTQMNYAVDVEGKSAEQVAREYLEQEGLLQ"
     gene            complement(2342..3073)
                     /locus_tag="AC1PIV_001621"
     CDS             complement(2342..3073)
                     /locus_tag="AC1PIV_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HIP6612629.1"
                     /translation="MIDYQNVSLTCKVSGPILKNLTFDIQEGEFFVLIGPSGSGKTTT
                     LKLINRLIEQTEGEVFFQGKRLKDFDLRELRLETGYVLQQIALFPNMTVAENIALIPE
                     MKGLGKEETLTRMRELLTKVGLEPDSYLDRLPKDLSGGEKQRIGILRAIIANPKVLLM
                     DEPFSALDPISKAQLQDLIKELHEEFKMTTVFVTHDMDEAVKLADRICLMQDGQVVQL
                     GSPDELRNRPANDFVKEFIRARGGM"
     gene            complement(3066..3515)
                     /locus_tag="AC1PIV_001622"
     CDS             complement(3066..3515)
                     /locus_tag="AC1PIV_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HIP6612630.1"
                     /translation="MMEVEKRSKDYARMFDQQVGLYEDYARGHGLNAKCLSILMWIYY
                     NPGGVTQNWVSKKTYSSKQVVNATVKKFLDGGLVVLEENPADKRHKKIKLTEEGQQFA
                     SRILDPLEEAENKALSQLSQEEQELMLGLIQRYSQSLMAILKGEDDD"
     gene            complement(3826..4362)
                     /locus_tag="AC1PIV_001623"
     CDS             complement(3826..4362)
                     /locus_tag="AC1PIV_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HIP6612631.1"
                     /translation="MVKKSSSVWTSLLLGAAGGAAAAAFLASKTGKTVKEKVVNFAND
                     YKENHEEINADFVTKAQDLGKQATERFTEVKTQLETGELTVEDLVKSGKEKSLETFEQ
                     IKEKIAEQNLSTADILEAIKAKTAKAPTVDLTEEDIEDAVVVSEDIEIDIEDVQTEVV
                     SETVSEVASETTSEAVEG"
     gene            complement(4346..4756)
                     /locus_tag="AC1PIV_001624"
     CDS             complement(4346..4756)
                     /locus_tag="AC1PIV_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HIP6612632.1"
                     /translation="MIEISVLIIALSIAAVAVYIVLLLKKLGTVTDEAQQTLKVLTSD
                     VNVTLYQTNELLAKTNVLVEDVNGKVSTLDPLFVAVADLSTSVSDLNASARDLTVKAK
                     SAGASTVKAGGALSALSTLSSLLGKKGEKNGKKI"
     gene            complement(4770..5546)
                     /gene="lgt"
                     /locus_tag="AC1PIV_001625"
     CDS             complement(4770..5546)
                     /gene="lgt"
                     /locus_tag="AC1PIV_001625"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HIP6612633.1"
                     /translation="MDPIAIKLGPLEIRWYAICILLGLILGVYLATKEGPRKKIRQDD
                     ILDFILIAFPLSILGARIYYVAFSWSEYKDNILSIFAIWNGGIAIYGGLITGAIVLYF
                     FTQYRFINTLDFLDIVAPSVMIAQAIGRWGNFFNQEAYGKAVESLNYLPAFIRDQMYI
                     DGAYRQPTFLFESLWNLLGFGLVCVLRRRPKFLKQGEITAFYLVWYGCGRLLIEGLRT
                     DSLMFLGIRVSQWLSGVLILVGIIMVVLRRRKSSIPFYQP"
     gene            complement(5548..6480)
                     /gene="hprK"
                     /locus_tag="AC1PIV_001626"
     CDS             complement(5548..6480)
                     /gene="hprK"
                     /locus_tag="AC1PIV_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="HIP6612634.1"
                     /translation="MTVYVKDLVDNLRIECVYSTEELLQKQITTADITRPGLEMTGYF
                     DYYAPERIQLIGMKEWSYLMAMTAHNRYQVLSQMFQPETPVVIVARGLEIPEEMYKAA
                     KEKQIAICRSKTATSRLSGELSSYLDSRLAQRTSVHGILMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDVYAKDDVTLWGEPAEILRHLLEIRGVGIIDIMSLYGAS
                     AVKDSSEVQLAVYLENFETGKVFDRLGNSGDTIEIAGIAIPQIRIPVKTGRNISVVIE
                     AAAMNYRAKQMGFDATKIFEERLSNLIEHNREEA"
     gene            6694..7638
                     /gene="manA"
                     /locus_tag="AC1PIV_001627"
     CDS             6694..7638
                     /gene="manA"
                     /locus_tag="AC1PIV_001627"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HIP6612635.1"
                     /translation="MMEPLFLTPVMHEKIWGGNRLRTNYHYDIPSDKTGECWAISAHP
                     NGVTTVSNGQYKGRGLDDLYKNEKHLFGNPTDDVFPLLTKILDADDWLSVQVHPDDSY
                     GLAHEGELGKTECWYILEAEEGAEIIYGHNAQSKEELRQQIEAGDWDKLLTHVPVKKG
                     DFFFVPSGTMHAIGKGILILETQQSSDTTYRVYDFDRRDDAGNLRELHIEKSIDVLTI
                     GPVANSTPAHLKAGNLDSTLLVANPFFTVYKWNIQQEIKMKQTVPYLLVSVIEGEGAI
                     QVGETSYPLQKGSHFILPANVTDWTFTGQMDIIASHAN"
     gene            complement(7681..>7841)
                     /locus_tag="AC1PIV_001628"
     CDS             complement(7681..>7841)
                     /locus_tag="AC1PIV_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HIP6612636.1"
                     /translation="GLLLGKSFLLLIALYIAAAYFLPYKEDRDAERYGTGPRKIKEAE
                     KINKSWFE"
BASE COUNT         2276 a         1884 c         1436 g         2245 t
ORIGIN      
        1 attactatta ttaaaaaaca gactttctca aacgagactg cctgctctgc ttttttccct
       61 taaaacttcc ctaaattcgt caagtctttt ttgtctggca tgacttcctt gttgtcccag
      121 tgctcgacaa tctttccgtc tttgaggcgg tagatgtcaa agtgagcgta gtcctgacct
      181 gcaatccaga ctttcgaata agccaccaca tagtcaccct gtcccatcac cttaaagaca
      241 aagtcgtagt tgacttgact ctctaccaga tagtccttat aggctacacc gccttgggcg
      301 atttcttggt tgtgctgaat aagatcagct gccacatagt cgtcaaattt ctcgattttc
      361 ccattttgaa ggacatcgac caagaaacga cggacgattt tcttgttgtc ctcagtctta
      421 tctaggtcag tcagctcaaa gtctgcgtaa atcgggtctg tttggccaat ggtttttgga
      481 taggcatcga taacatccca atgctcaacg atacaaccat tttcatccga acggaaaatg
      541 tctgccgtca cccactcagc cgcaccgtca ttgagtttct ggtggacatg gacaaagaca
      601 aaattcccgt cctcaatggc acggacgata ttgatttccc gcttgggatt gcgtttgaaa
      661 aagtcctcaa agaaagccgc aaagccctct ttctcatcag gcacacccgt actgtgctgg
      721 gtatagctgg ctcccatata gttttcatga acttccttga tttcgccatc gcgaatgcca
      781 cgaaggtaaa gatttttagc attttctagt tgatttgaca tgattttctc ttattgtaac
      841 aatccttctt gttctaaata ttccctcgcc acttgctctg ccgacttgcc ttccacatcg
      901 accgcatagt tcatctgggt catttcctcg gtcgagatgt tgcctgccaa gacccctagg
      961 acttgctcca actcaggata ttgttctaag gtttctttgg acaatagcgg agcggcctgg
     1021 taaggtggga agagctgttt gtcgtcttcc aggattttga gcttgtaggt gaccaccttg
     1081 ctgtctgtag aatatgcttc gataatctgc acattaccac tcttaatagc ttcataacga
     1141 agggctggct ccatggtctt gacattgagt tggagattgt agagattttt tagaccgata
     1201 ttaccatctt cgcggtcgtt aaactctaaa gagaagccag cgacagctgt ctgctgcact
     1261 tttgccaaat ccgaaatctt ctcaagaccg tttttctgag cataatcttc cgttacagcc
     1321 aaagcatagg tattctggaa agccattggt gctaaataca tcagaccatc ctgttccaaa
     1381 atcgcttctt tagcgtaggt ataaacctcc tcaggattcg ttgataaatc cattggtgaa
     1441 tttttcaaaa gagtacttgt aatggtccct gtgtactcag gataaatatc aatagaacct
     1501 gatttgagtg cctcataaag gaagctagtc tttccgaaat taggttttat ctccaccttg
     1561 atgtctgtct ggtcctcaat cagcaactta tacatattga tgagaatttc aggttctgca
     1621 ccgagcttcc ctgcaatgac caactgtttt gtggaaaaat taagcatggg aacataacta
     1681 gctccaacag taaataaagt caccaataga gccaataaaa ttgtcttggg tttcttgtcc
     1741 tgcaacagac gaatgccata accaaaaagc actgcaagga cagccgacga taccgcacca
     1801 atcaaaatca gggctgaatc attgcggtca attccaagta gaataaagga gcccaggccc
     1861 ccagccccca ccaaggccgc cagagtcgcc gttccgataa tcataatgga agccgtccga
     1921 atccctgaca tcaaaatagg catggcaaga gctaacttaa attttttcaa cttctcccat
     1981 ttattcatac caaaagcggt tgctgcttct tccagagaag ggtcgatttc tccaagtcct
     2041 gtcaatgtcc cctgcaagat aggaaagata gcataaataa caagtgctac tactgctggc
     2101 aaggttccga ttcccataaa aggaatgaaa agaccaagca aagcaaggga tggaatagtt
     2161 tggaagatac ctgttatttg cagactccac tcggtcaagc gttttttact agatagaatc
     2221 agtcccaaag gtactgcaat tgcaatcgca ataatcaaag ctagaaggga gatgcgaagg
     2281 tgttcaaaaa gagcaattcc ccactcgtcc ttgcgttcta taaaggtttc aaataggttc
     2341 attacatacc tcctcgagct ctgataaatt ccttgacaaa atcattggca ggacgattcc
     2401 tcaattcatc aggacttcct aattgcacaa cttgtccatc ttgcatgaga cagatgcgat
     2461 ccgccaattt aaccgcctca tccatatcat gggtaacgaa aactgttgtc atcttgaatt
     2521 cctcatgtaa ttccttaatc aagtcctgca actgagcctt actgattgga tccagagctg
     2581 agaaaggttc gtccatgagt aacactttcg gatttgcaat gatggcccgc aaaatcccga
     2641 tccgctgttt ttctcctcca gacaagtcct tgggcaaacg atccagatag ctgtctggtt
     2701 ccaagccaac cttggtcaat agctctctca tcctcgtcag ggtttcttcc ttgcccaaac
     2761 ctttcatttc aggaataaga gcaatgtttt cagctaccgt catatttgga aaaagggcta
     2821 tctgctgaag aacataacct gtctccaaac gtaattcacg caggtcgaaa tccttaagtc
     2881 gcttaccttg aaaaaaaacc tctccctcgg tctgctcaat tagacggtta atcaatttca
     2941 acgtagttgt ctttccgcta ccactcggtc caatcaagac aaagaactcc ccttcttgaa
     3001 tatcaaaggt caaatttttc aagattggtc cactaacctt acaggtcaga gatacatttt
     3061 gataatcaat catcatcttc tccttttaaa atagccatga gactctgact gtagcgctga
     3121 attaatccta gcataagctc ctgttcctcc tgactgagtt gagacagcgc cttattttcc
     3181 gcctcctcta agggatccaa aatgcgacta gcaaattgtt gcccctcctc tgtcaattta
     3241 attttcttat gtcgcttatc tgctggattc tcctctaaaa ctaccaggcc tccatccaaa
     3301 aatttcttta cagtagcatt gacaacttgt ttgcttgaat aggtcttctt actgacccag
     3361 ttttgcgtca cacctccggg attataataa atccacatga gaatggataa acattttgca
     3421 ttgagtccat gtccacgagc atagtcttca taaagaccga cttgctggtc aaacatacga
     3481 gcataatcct tactcctttt ctcaacttcc atcatccttc cccctcctca gtgagcacaa
     3541 ctaccttact aaaagcctct ggtctactag tgttcaaaac aacaacaatt ttcacaacga
     3601 cttcctcctg taatcatgtt agtcaatatt ttttactatt ttaccaaaaa aagaaaaata
     3661 gtcaatcatt ttgactattt tgagacatca actaccttat tatagattcc cgtcttcatc
     3721 cattcaaaca tattaaatcc ctgaaattat ctgcttttaa tttacacaaa acaaatgata
     3781 atcagataac aaaactagcc tagaaaattc taagctagtt tcattttatc cttcaactgc
     3841 ttctgaggta gtttcgcttg ctacttctga aacagtttct gataccactt cagtttgaac
     3901 atcttcgata tcaatttcaa tatcttcaga cacaactaca gcatcctcaa tatcttcttc
     3961 tgtcaaatcc actgtcggag ctttagcagt ttttgccttg atagcttcca aaatgtcagc
     4021 cgttgataag ttttgttccg caattttttc cttgatttgc tcaaaggttt ccaaggattt
     4081 ttccttacca gacttgacca aatcttctac tgtcaattca ccagtttcaa gttgagtttt
     4141 tacttcagta aatcgttcag tcgcttgttt gcctaaatct tgtgccttag tgacaaaatc
     4201 agcattgatt tcttcatggt tttctttata gtcattagca aagtttacaa ctttttcttt
     4261 gactgtttta ccagttttac ttgctagaaa agcagctgca gcagctccgc cggctgcccc
     4321 taacaaaagg ctagtccaca cgctactaga tttttttacc atttttttct cctttcttac
     4381 ctaagagaga tgagagagtt gacagagctg aaagagctcc gccggctttt acagtacttg
     4441 ctccagcaga cttggctttg actgtcaaat cacgcgctga agcattcaaa tctgatacag
     4501 aagttgacaa gtcagctacc gctacaaaaa gaggatcaag ggtcgaaacc ttgccattta
     4561 catcttcgac taaaacattg gttttagcca aaagctcgtt ggtctgatag agagtcacat
     4621 tgacatcgct ggtcaagacc ttaagcgttt gctgggcttc atccgttacc gtacccaatt
     4681 ttttcaacaa caaaacaata tatactgcca ccgccgcgat ggacaaggca ataatcaaga
     4741 cagaaatttc aataatcata tcttctcctt tagggttgat agaatggaat agaagacttt
     4801 cttctccgca acacaaccat gataatacca acgaggatta acaccccaga tagccattgt
     4861 gaaacacgta ttcccaagaa catgaggctg tccgtccgca agccttctat caaaaggcga
     4921 ccacaaccat accagactag gtagaaagct gtaatttctc cctgtttaag gaattttggc
     4981 cgtctacgta acacacaaac caagccaaag cctagcaaat tccagagaga ctcaaacaag
     5041 aaggttggtt gacggtaggc accatcaata tacatctggt ctcggataaa ggctggcagg
     5101 tagttcaaac tttctactgc cttaccatag gcctcttggt taaagaaatt tccccaacga
     5161 cctattgcct gagcaatcat gaccgatggc gctacaatat ccaaaaaatc cagggtatta
     5221 ataaagcgat actgggtaaa gaaataaagg acgattgcac ctgtaatcaa accaccatag
     5281 atggcaatac caccgttcca gatagcgaag atagataaaa tgttatcctt atattcactc
     5341 catgaaaagg cgacgtagta aatccgtgcc cctaggatag aaagcggaaa tgcgattaga
     5401 ataaaatcta aaatatcatc ctgacgaatt ttctttcgcg gaccctcttt tgtcgccaga
     5461 taaacaccta gaatcagacc aagcaaaatg cagattgcat accaacgaat ttctaaggga
     5521 cctaatttaa tcgcaatagg atccatatta agcctcttct ctattgtgtt caattagatt
     5581 agacaagcgt tcttcgaaga tcttcgttgc atcaaacccc atctgtttgg cacggtagtt
     5641 catggctgct gcttcaatta cgacagaaat atttcgaccg gtttttacag gaatacgtat
     5701 ttgtggaata gcaattcctg ctatttcgat agtatcgcca gagtttccca aacggtcaaa
     5761 taccttacct gtttcaaaat tttcaagata gacagctaat tgcacttctg atgaatcttt
     5821 cacggcacta gcaccgtata gactcatgat gtcgataatg ccgacccctc gaatttctaa
     5881 taagtggcgc agaatttccg caggttcacc ccagagagta acatcatctt ttgcatagac
     5941 atcaacacgg tcatcagcca ccaatcggtg tcctcgttta accaactcaa gaccagtctc
     6001 actcttaccg ataccagaat caccctggat aagcacaccc ataccgtaaa tgtccatcaa
     6061 gataccgtgt acactcgtcc gctgagccag gcgactatcc aagtaagaag acaattctcc
     6121 cgatagacga ctggttgctg tcttgcttcg gcagatagca atttgttttt cttttgcagc
     6181 cttgtacatc tcctcaggga tttccaagcc acgtgccact atgacaacag gggtttctgg
     6241 ctggaacatc tgagaaagaa cctgatagcg gttatgggca gtcatggcca tcaaataaga
     6301 ccactccttc atcccaatca actggatgcg ctctggagca taataatcaa aatagccagt
     6361 catttccaat cctggtcggg taatatctgc cgtcgtaatt tgcttttgca ggagctcttc
     6421 cgtactgtaa acacattcaa tccgcagatt atcgaccaaa tctttcacat aaacggtcat
     6481 ttcttccctc actttcagtt ttattatatt ataccataag ctaggggttg ggggaaaaac
     6541 aagtggctga tttggcaaaa agaatgagtt ctttcttttt ctcacaaaat tagcaaaact
     6601 tccacagatt aaatgtactt ctcttccttc gctacatatt tttaacaaat ctgttatact
     6661 ttatatagat caatacttac tactaaggag aaaatcatgg aacccttgtt tctcacacct
     6721 gttatgcacg aaaaaatttg ggggggcaat cgcttaagga ccaactacca ctacgacatt
     6781 cctagtgata agactgggga atgttgggca atctctgccc atccaaatgg cgtaactact
     6841 gtctcaaacg gtcaatataa aggaagagga ctggatgacc tctataagaa tgaaaaacat
     6901 ttatttggca atccaacaga tgatgtcttt ccattattaa caaaaatcct tgatgcagac
     6961 gattggctta gcgtccaagt tcatcccgat gatagctatg gcttggctca cgaaggggaa
     7021 ctgggcaaga cagaatgttg gtacattttg gaagccgagg aaggcgctga aatcatttat
     7081 ggtcacaatg cccaatccaa agaagaactc cgtcagcaaa tcgaagccgg agattgggac
     7141 aagctgttga cccatgtacc cgtcaaaaag ggtgatttct tctttgtacc aagcggcacc
     7201 atgcacgcca tcggtaaggg aatcctgatt ttagaaaccc aacaatctag tgatacaacc
     7261 taccgtgtct atgactttga ccgccgtgac gatgcaggca acctccgtga actacacatt
     7321 gagaaatcga ttgacgtgct gaccatcgga cctgttgcta actcaacacc tgcccacctc
     7381 aaagcaggca atcttgactc gacacttctg gttgccaatc ccttctttac cgtatataaa
     7441 tggaatatcc aacaagaaat caaaatgaaa cagacagttc cttacctgct tgtcagtgtc
     7501 attgaagggg aaggtgccat ccaagtcggt gaaaccagct acccacttca aaaaggaagc
     7561 cactttatct taccagccaa tgtgacagac tggacattta caggccaaat ggacatcatc
     7621 gccagtcacg cgaactaagc atacaaaaaa cttgagcctt taaactcaag tttttttgca
     7681 ttattcaaac caagacttat ttatcttttc cgcttctttt atcttacgtg gacctgttcc
     7741 atagcgttcc gcgtccctat cttccttata aggtaaaaaa taagctgctg caatatagag
     7801 agcaattaga aggaggaagg atttgcctaa gaggagacct g
//
LOCUS       DBNFCO010000077         7775 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.077, whole genome shotgun sequence.
ACCESSION   DBNFCO010000077 DBNFCO010000000
VERSION     DBNFCO010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 7775)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7775)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7775
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.077"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            <1..520
                     /locus_tag="AC1PIV_001629"
     CDS             <1..520
                     /locus_tag="AC1PIV_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIP6612637.1"
                     /translation="KRPIHLYIFVILSSIASILRLFSAFVSTFNEERLRTSVQGVVGI
                     DVEELILVSRETANLQTGIIQKTAALVMFGLLIAVIVFLFMKKNELASYLYIGYLFST
                     LLLNTYSYLAGKGIANLYSDAALRDVTAAGMLGAYILNIVLFAIYFGVTVFFHLRKPK
                     EKPSTAINSTDI"
     gene            complement(573..1487)
                     /locus_tag="AC1PIV_001630"
     CDS             complement(573..1487)
                     /locus_tag="AC1PIV_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HIP6612638.1"
                     /translation="MKTFLRRKGIACQLLAAIFIVGINLQSPPSASANARGDDYPYTA
                     VDAVDPWRLYTRQCTSFVAFRLSTVNGFTLPPAYGDANVWGHRAKQEGYQVNMTPAVG
                     AVAWWETPMHVAWVSAVNGDTVEIEEYNYGVRYTYGRRVIPKNAVSGYIHFKNLGAGT
                     TNSQPALAPSGTYTFTSQLAIKSQASLSSPTLDYYYAGESVRYDKVLEDDGQRWISYI
                     SYSGARRYIAIQPTITQSTNNSLPASGSYTIQSYSSVRNNPSLSSPEITFYGAGSVVR
                     YDKVITAEGRTWISYISYSGARRYIAIS"
     gene            complement(1667..3355)
                     /gene="argS"
                     /locus_tag="AC1PIV_001631"
     CDS             complement(1667..3355)
                     /gene="argS"
                     /locus_tag="AC1PIV_001631"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HIP6612639.1"
                     /translation="MNQKQVIAERLAAILPSLEVEAIYNLLEKPKSSEMGDIAFPAFS
                     LAKVERKAPQAIAADIVEKLDTTGFENVVATGPYVNFFLDKAAISHQVLTDVITEKDQ
                     YGKLNIGQGRNVTIDMSSPNIAKPFSVGHLRSTVIGDALANIHEKLGYKPIRINHLGD
                     WGKQFGMLIVAYKLWGDKAAVEADPISELLKLYVRINAEAEEKPELDDEARQWFKKLE
                     DGDPEAHELWQWFRDESLVEFNRIYDKLDVTFDSYNGEAFYNDKMDEGIQILEEKGLL
                     QESKGAKIVDLESYNLPPALIMKTDGATLYITRDMATAMYRKRTYDFVKSIYVVGQEQ
                     INHFKQLKAVLKEMDFDWSDDMTHITFGLVTKDKKKLSTRKGNIILLEPTLDEAISRA
                     LTQIEAKNPDLENKEEVAHAVGVGAVKFYDLKTDRDNGYDFDLEAMVSFEGETGPYVQ
                     YAYARIQSILRKANFVPNAENDYKLADTESWEIIKHIQNFSAVVERAGDKFDPSLIAK
                     YAINLAQAFNKYYAHTRILDESPERDSRLALAYATGLVLKEALRLLGVKAPEKM"
     gene            3462..3902
                     /gene="argR"
                     /locus_tag="AC1PIV_001632"
     CDS             3462..3902
                     /gene="argR"
                     /locus_tag="AC1PIV_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006525 - arginine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HIP6612640.1"
                     /translation="MNKAGRHDLIKAMIRQEKIGRQTDIQQGLEARGVVVTQTTLSRD
                     LRELGVIKIHENGRSFYSLAIEEERVNFIQLLAQYAYKVDRASFILVLHSELGEAALM
                     ANIIDAEKPETILGTLAGANTLLVICRDDVAAQQVEAEINYYLN"
     gene            3917..6457
                     /gene="mutS"
                     /locus_tag="AC1PIV_001633"
     CDS             3917..6457
                     /gene="mutS"
                     /locus_tag="AC1PIV_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HIP6612641.1"
                     /translation="MATEKISPGMQQYLDIKAQYPDAFLLFRMGDFYELFYEDAVEAA
                     QILELSLTSRNKNAENPIPMAGVPYHAAQQYIDTLVELGHKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVTDSSKMGADSNYLVAIDRQGVQFALSYMDVSTGQFFVTSLDDFTS
                     LCGEIRNLRARELVIGYALSEEEEQVFSNQMNLLLSFEDEVTEDVQLIDNSLTDLEKA
                     AAGKLLSYLHRTQMRDLSHLQKVVHYEIKDYLQMDYATKSSLDLLENGRTGKKHGSLY
                     WLLDETKTAMGMRLLRTWIDRPLIDLKRIENRQAVVQVFLDYFFERSDLVEALKGVYD
                     IERLASRVSFGKTMPKDLLQLSQTLGNIPAIKNILQQINEPALGNLVAGLDPIPELHA
                     LISSAIDPEAQGTITDGNIIRTGFDETLDQYRLVMREGAGWIAEIEAKEREASGINNL
                     KIDYNKKDGYYFHVTNSNLGNVPDHFFRKATLKNSERYGTEELAKIEGQMLEARDKSA
                     NLEYEIFMRIRQEVEKYIGRLQKLARTIATIDVLQAFAVVAEQQHLVCPRFTDQRELT
                     IDRGRHAVVEKVMGKQTYIPNSIHLNTDTHMQLITGPNMSGKSTYMRQLAVIVIMAQM
                     GSYVPADQAELPIFDAIFTRIGAADDLVSGQSTFMVEMMEANKAVRLATDRSLILFDE
                     LGRGTATYDGMALAQSIIEYIHDKIGAKTLFATHYHELTDLSQTLEHLENVHVSTLEK
                     DGQVTFLHKIAQGPADKSYGIHVAKIAGMPEELLQRADRILQTLENQAPTAPTHPAPS
                     VVEEPSGQLDLFADTPSHPVLDELEKLDIYNMTPMEVMMAVAELKKKI"
     gene            6589..7032
                     /locus_tag="AC1PIV_001634"
     CDS             6589..7032
                     /locus_tag="AC1PIV_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HIP6612642.1"
                     /translation="MKVKLAISSEILEDLVTIEAQAMSEQITNLVTYIQNLDKQRSSL
                     TVKKGEQVYLVEHDEIVRLYLEDRVLQVETVETTYTSNLRLYQVKEDLPANFLQISQS
                     EIIHIKQLDHLKLTANGLVKLVMKNGSVTYSSRRYLKVIKERLGL"
     gene            7029..7469
                     /locus_tag="AC1PIV_001635"
     CDS             7029..7469
                     /locus_tag="AC1PIV_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HIP6612643.1"
                     /translation="MKKYILSASLGIAIGTIISIITSAVFGQGTYLPLNPFSTMGAYY
                     LSNFSQVTVMLICVAIWATIGILFQLADKIFEQDWSLLRMTATHFGFTVLGFTPLGIL
                     AGWFPVKLGALLFFWLIFVLVYALLFFLNYRKMERQIKDINGRL"
     gene            7503..7691
                     /locus_tag="AC1PIV_001636"
     CDS             7503..7691
                     /locus_tag="AC1PIV_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612644.1"
                     /translation="MKIILTIVYSLGVVWNTLYIAYNVGKLPLLNLLWPAVILVACAI
                     NLYFLWTRKQESESMSLS"
BASE COUNT         2047 a         1570 c         1934 g         2224 t
ORIGIN      
        1 gaaaagaccg attcatttgt atatttttgt gatactatcc agtattgcca gtattttaag
       61 gctgtttagt gcctttgtgt cgacttttaa tgaggagcga cttcgtacgt ctgtgcaggg
      121 agttgttggg attgatgtag aagaattgat tcttgtttcg agagaaacag ccaatctcca
      181 gacgggtatc attcaaaaga cagcagccct ggtcatgttt ggtcttttga ttgcggtcat
      241 tgtcttctta ttcatgaaga aaaatgagct ggcttcttat ctttacatcg gctatctatt
      301 ttcgacctta ctgctgaata cctatagcta cctagcaggt aaggggattg ccaacctcta
      361 ctcagatgca gccttgcgtg atgtgacagc agcaggtatg ctaggggctt acatccttaa
      421 cattgtccta tttgccattt actttggtgt gaccgtcttc ttccatctgc gtaaaccgaa
      481 agaaaaaccg agcacagcta ttaattcgac agatatttaa tgaaaaagca cagtctaaaa
      541 gattgtgctt ttaaatattg tattttttgt gattaggaga tggcgatgta gcgtcgagca
      601 cctgagtaac tgatatagct aatccatgtg cgaccttcgg cagtaataac tttatcatag
      661 cgaacgactg agccagctcc gtagaaggtg atttcaggac tggacagact tggattgttg
      721 cggacactag agtaggactg gatggtgtag ctacctgatg ctggtaggct gttgtttgta
      781 gattgagtaa tggtaggctg gatggcgata tagcgccgag ctccagaata gctgatatag
      841 ctaatccagc gttgtccgtc gtcttcaaga accttgtcgt agcggacgct ttcgccagca
      901 taatagtaat cgagggtagg gctagataga ctagcttgag atttgatggc cagttggctg
      961 gtaaaggtat aggtgccgct tggggctaag gcgggttgag agttggttgt tcccgctccg
     1021 aggtttttaa aatgaatgta gccgctaacg gcatttttgg ggataactcg ccttccgtag
     1081 gtatagcgaa caccgtagtt gtattcctca atctctacgg tatctccatt tactgcagaa
     1141 acccatgcga catgcatggg agtttcccac caggcaacgg ctccgacagc aggtgtcata
     1201 ttaacttgat aaccttcttg tttggcacga tggccccaaa cattggcatc accataggca
     1261 ggtggcaatg taaaaccgtt aactgtgcta agtcgaaagg ctacaaagga ggtgcactgg
     1321 cgtgtgtaga gtctccatgg atcgactgca tcaactgctg tgtagggata gtcatctcct
     1381 cttgcattgg ctgaggctga aggtggggat tgtaaattga taccgacaat aaaaatggcg
     1441 gctagaagct gacaggcgat tccttttctt ctcaagaatg ttttcattat ttctccttgt
     1501 gtagtagatg tagaggtatc acgtgtacct cccatctata tattcgtaat tgaaatgaat
     1561 ctttttgatt ttcatttggg agaaggagtt gttgtgataa ggaatcggaa acgagagtag
     1621 gcaatgtggt agaaaaaaag cctcggctga tggccgaagg ctttgattac attttttctg
     1681 gtgcttttac gccgagaaga cgcagagctt ctttgaggac aagtcctgtt gcgtaggcaa
     1741 gtgccaagcg gctgtcacgc tctggacttt catccaagat acgcgtgtgg gcgtagtatt
     1801 tgttgaaggc ttgagctagg ttgatagcgt atttggcaat aagtgatggg tcaaatttgt
     1861 ctccggcacg ttctacaaca gctgagaagt tttggatgtg cttgatgatt tcccagcttt
     1921 ctgtgtcagc cagtttgtag tcattttctg cgtttggtac aaagtttgcc ttgcgtagga
     1981 tagactggat gcgggcgtat gcgtattgta cataaggacc tgtttcaccc tcgaaggaaa
     2041 ccatagcttc caagtcgaag tcgtagccgt tgtcacggtc ggttttgagg tcgtagaact
     2101 tcacagcgcc gacaccaact gcgtgtgcca cttcttcctt gttttcaagg tcagggtttt
     2161 tagcttcaat ttgagtaagg gcgcgtgaaa tagcttcgtc tagagttggc tcgagcagga
     2221 tgatgtttcc tttacgagta gagagctttt tcttgtcctt ggtcactaga ccgaaggtga
     2281 tatgggtcat atcgtcgctc cagtcgaaat ccatttcctt caaaacggct ttgagttgct
     2341 tgaagtggtt gatttgctcc tgaccaacga catagatgct tttcacgaag tcataggtgc
     2401 gcttgcggta catagctgtt gccatatcgc gcgtgatgta gagggtagcg ccatctgtct
     2461 tcatgataag ggctggtgga agattgtagc tttcaaggtc aacgattttg gcacctttag
     2521 actcttgaag aagtcctttt tcttctaaga tttggatacc ttcgtccatc ttatcgttgt
     2581 agaaggcttc gccgttatag ctgtcgaatg ttacatcaag tttgtcgtag atgcggttaa
     2641 attcgaccaa gctctcatca cggaaccatt gccacaattc atgcgcttct gggtcgccgt
     2701 cttccaattt tttgaaccat tggcgtgctt cgtcgtccaa ctcaggtttt tcttctgcct
     2761 cagcattgat acggacatag agtttaagaa gttctgagat tgggtcagct tcgaccgcag
     2821 ccttgtcacc ccagagtttg taggcaacaa tcaacatgcc aaattgtttg ccccagtcac
     2881 ccaagtggtt gatacggatt ggcttgtagc ctagtttttc gtggatgttg gcaagggcat
     2941 cgccgataac ggttgagcgt aaatgtccaa ctgagaatgg tttagcaatg tttggactag
     3001 acatgtcgat ggttacattg cgtccttgac caatgttgag tttaccgtat tggtcttttt
     3061 cagtaataac atctgtcaag acttggtggg aaatcgcagc cttgtccaag aagaagttga
     3121 cgtaaggacc agttgcaaca acgttctcaa agccagttgt atcgagtttt tcaacgatgt
     3181 ccgctgcgat agcctgtgga gccttgcgtt ccactttagc aagtgagaag gctgggaagg
     3241 caatatcgcc catttctgat gattttggtt tttctagcag attgtagata gcttccactt
     3301 ccaaactcgg aaggatggca gccaatcttt ctgcaatcac ttgtttttga ttcatatagg
     3361 atttcctcca aagttattga ttctatttta acacatttct aggctaatag cggggaaaag
     3421 tgttataata tttctataaa tatacatttt gaggtaaaat gatgaataaa gcaggacgac
     3481 atgatttaat aaaggccatg attcgtcaag aaaaaatagg gcgacaaacg gatattcagc
     3541 aaggtttaga ggctcgaggg gtagtggtaa cccagacaac cttgtctcgt gatttacgtg
     3601 agttgggagt gataaaaatt catgaaaacg ggcgttcatt ttattcctta gctatcgaag
     3661 aagagcgcgt gaattttatc caattattgg cacaatatgc gtataaagta gatagggcta
     3721 gttttattct ggtccttcat tcagaactgg gagaagcggc cttgatggcc aatatcattg
     3781 atgcagaaaa gccagagact attttgggaa cgctggcggg agctaataca cttttagtta
     3841 tttgtcgaga tgatgtagcg gctcagcaag ttgaagcgga gattaactac tatttgaatt
     3901 agaacaagga gagatgatgg caacagaaaa aatttctccg ggaatgcagc agtatctgga
     3961 tataaaagca cagtatccag atgctttttt gcttttccgt atgggagact tttatgaatt
     4021 attttatgaa gatgcggtag aagcggcaca gattttggaa ttgtccttga ccagtcggaa
     4081 taagaatgcg gaaaatccga ttcccatggc gggggtaccg tatcacgcgg cacaacagta
     4141 tatcgacaca cttgttgaat tggggcacaa ggtcgcaatt gccgagcaga tggaagatcc
     4201 taagcaggca gtcggcgtgg tcaagcggga agtagtgcag gtcattactc ctggtacggt
     4261 aacagactcg tccaaaatgg gagcagacag taactatttg gttgcgattg accgtcaggg
     4321 agtacagttc gcgctttctt atatggatgt gtcaacaggt cagttttttg tgactagttt
     4381 ggatgatttt actagtcttt gcggtgagat ccgcaattta cgggcacgtg aattggtcat
     4441 cggctatgct ttatctgagg aagaagagca ggtcttttcg aaccagatga acctcctgct
     4501 ctcttttgag gatgaggtga cggaagatgt ccagctgatt gacaactcct tgacagactt
     4561 ggaaaaggct gcggcaggta aactcctcag ctacctacat cggactcaga tgcgagatct
     4621 gagccacttg caaaaggtgg tccactatga aatcaaggac tatctgcaaa tggactatgc
     4681 aaccaagtcc agtctggacc tgcttgaaaa cggtcggaca ggcaagaagc atggtagttt
     4741 gtactggttg ctagacgaaa ctaagacagc catgggtatg cgactattgc ggacatggat
     4801 tgatcgtccc ttgattgatc ttaagcggat tgagaatcgt caggctgtcg ttcaggtttt
     4861 tctggattac ttctttgaac ggagtgactt ggtcgaggct ttaaaaggtg tctatgacat
     4921 cgaacgtttg gccagccggg tgtcttttgg aaaaaccatg cccaaggatc tcttgcagct
     4981 ctcccagact ttgggaaata tcccagcaat caagaatatc ttgcaacaaa tcaatgagcc
     5041 tgctctaggc aatttggtgg ctggattgga cccaatccca gaactgcacg ctctcatcag
     5101 ctctgctatt gacccagaag cccaagggac catcacagat ggaaacatca tccgtacagg
     5161 ctttgacgaa acgctggatc agtatcgtct agtcatgcgt gagggagcgg gttggattgc
     5221 ggagattgag gccaaggagc gtgaagcatc tggtatcaat aatcttaaga ttgattacaa
     5281 taaaaaagac ggttactatt tccatgttac caattccaat ctgggcaatg tgccggacca
     5341 ttttttccgt aaggcgacct tgaaaaactc ggagcgctat ggaacggaag agttggctaa
     5401 gattgaaggg cagatgttgg aggcgcgtga taagtctgct aatttggagt acgagatttt
     5461 catgcggatt cgccaagagg ttgagaagta tataggtcgc ttgcagaagc tggctcggac
     5521 cattgcaacc atcgatgttt tgcaggcctt tgcagttgtg gcggagcagc aacatttggt
     5581 ttgtccacgc tttacagatc aaagagaact gaccattgac cgtggtcgtc atgcggtggt
     5641 ggagaaggtc atgggcaagc agacctacat tcccaactct attcacttga ataccgatac
     5701 acatatgcaa ctgattactg gtccaaacat gagtggtaag tctacctata tgcgacagtt
     5761 ggcggttatc gtcatcatgg cgcagatggg ttcctatgtg cctgcggatc aggctgaatt
     5821 accgattttc gatgctattt tcacccgaat tggggcggca gacgacttgg ttagtggtca
     5881 atcgaccttc atggtcgaaa tgatggaggc caataaggcg gtccgtctgg cgacagatcg
     5941 gtcgctcatc ctctttgatg agttgggacg gggaacggcc acctatgacg gtatggccct
     6001 ggcccagtct atcatcgagt acatccatga caagattggt gccaagactc tctttgccac
     6061 ccactaccat gagttgacag accttagcca gaccttggaa cacttagaga atgtccatgt
     6121 atcgaccttg gagaaggacg gccaagtcac cttcctccac aagattgccc aaggtccagc
     6181 tgacaagtcc tacgggattc atgtggctaa gattgcggga atgccagagg aactattgca
     6241 gcgggcagat cggattttgc agacgcttga aaaccaagcc cctactgcac caactcaccc
     6301 agctccgtca gtagtggaag aaccgtcagg tcaacttgat ctcttcgcag acacgccttc
     6361 tcacccagta cttgatgaac tggaaaaact agacatctac aatatgaccc ctatggaagt
     6421 catgatggcg gtggcggagt tgaagaaaaa aatataagac aatgaaagtc aggacagttg
     6481 ttctggcttt tttgccgttt agtgctggaa aatgaccaca tagccaaaag cccttgaaac
     6541 cagtaaagaa atggtgttta atagggtcag aaagagaaag gagagaatat gaaagtaaaa
     6601 ctagccatat catcagagat tttggaagat ttggtgacta ttgaagctca agctatgtct
     6661 gagcaaatta ctaacttggt gacctatatt caaaacttgg ataagcagag atccagtcta
     6721 actgttaaaa aaggggagca ggtctatctt gtggaacatg atgagattgt cagactctac
     6781 ttggaagata gggttttaca ggtggaaaca gtagaaacta cctatacttc caacctacgc
     6841 ttgtatcagg ttaaggagga cttgccggca aactttttac aaatctctca gtcggaaatc
     6901 attcacatca agcaactgga ccacctcaaa ctgactgcta acggtctggt caaactggtc
     6961 atgaagaatg gctcggtcac ctactcctcc cgtcgctatc taaaagttat caaagaaagg
     7021 ttaggactat gaaaaaatac atcttatcag ccagtttagg catcgccatc ggaaccatta
     7081 tctccattat cacatcagcc gtcttcggac agggaaccta ccttcctcta aatccctttt
     7141 caaccatggg tgcttactac ctgagcaact ttagtcaagt aaccgtcatg ttgatttgtg
     7201 tagccatttg ggcgacaatc ggtatcttgt ttcagctggc agacaagatt tttgaacagg
     7261 attggagcct tttacgaatg acggcaacgc attttggttt cacggtttta ggctttacac
     7321 cgctgggcat tttggctggc tggtttcccg tgaaacttgg ggcccttctc tttttctggc
     7381 tcatctttgt cttggtatac gctctgctat ttttcctaaa ctatcggaaa atggaacggc
     7441 agattaagga catcaatggt cgtttgtagt ataatagcac tatcatttaa ttggagtgtc
     7501 ttatgaaaat tattttgacg attgtctata gcttgggggt agtgtggaat actctctata
     7561 ttgcctacaa tgtcggtaaa cttcctttgt taaatttgct ttggcctgct gtgattttag
     7621 tggcctgtgc catcaatttg tactttttat ggaccagaaa acaagagtca gaatcaatgt
     7681 cattaagtta agcatttaag cagctaaaga aactattccc gtctgagcaa ttgatgacaa
     7741 aacgggaata gtttttgtat ttagggcgca caaaa
//
LOCUS       DBNFCO010000078         7197 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.078, whole genome shotgun sequence.
ACCESSION   DBNFCO010000078 DBNFCO010000000
VERSION     DBNFCO010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 7197)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7197)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7197
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.078"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(26..661)
                     /gene="serB"
                     /locus_tag="AC1PIV_001637"
     CDS             complement(26..661)
                     /gene="serB"
                     /locus_tag="AC1PIV_001637"
                     /EC_number="3.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036424 - L-phosphoserine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006564 - L-serine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoserine phosphatase SerB"
                     /protein_id="HIP6612645.1"
                     /translation="MTTGLLVMDVDSTLILEEGIDLLGEEAGLGAQVAAITERAMRGE
                     LDFEEALRERVALLKGLPVSVFDRIIKKIHFTPGAAELVSELKMRGYKVAVVSGGFHE
                     TVDRLAAQLELDYVRANRLEVVDGVLTGQVLGEIVTKDTKKACLEEWAAENGLSLSQT
                     IAMGDGANDLPMIQRAGIGVAFCAKPIVQEQVPYQINEKNLYKLIEILDSK"
     gene            complement(713..2437)
                     /gene="ezrA"
                     /locus_tag="AC1PIV_001638"
     CDS             complement(713..2437)
                     /gene="ezrA"
                     /locus_tag="AC1PIV_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HIP6612646.1"
                     /translation="MPTGTIILIVSIVIILIIAYVACLIVRKRNDNLLVALEERKEEL
                     FNLPVNEEVETVKALHLIGQSQVSFREWNQKWVDLSLNSFADIENHIFEAEGYNNAFR
                     FVSAKNAIDSIDSQIDLIEEDIASIRQGLMELKEQEEKNSGRVKHALNLFDSLQEAVR
                     ENPDSYGETLSELEKQLKNIEVEFSEFVMLNSSGDPIEASEILDKTEEHMIALNQIMD
                     RIPSLIERVTKDFPEQLEDLESGYRKLVEQNYLFTEANIESQFQNIRVSIRENTALIV
                     SFDLDAAEAENEGIQAKIDHLYKVFNREIEANKEAVKISKNLPKFLEHVVQNTQLLDE
                     ESQRLNATYLLADSKLSRINQLKARLESIEIVVTESVEDIENPQVAYSILEERLDHSL
                     ASLKEIEEEQLVLADYLKSQELSENTARKKATLYINKLHTLKRYMEKRNLPGIPAEFL
                     TNFFRTSDHVEALIAELDYKRINIEVVNRLLENATYDMNQLEELAYLIVQNATLTEQL
                     LQYSNRYRSFDESVQKAFNRSLSIFEKDFDYQAAFEEISFALETVEPGVTERFVRSYE
                     KTREAIRY"
     gene            complement(2526..4478)
                     /gene="gyrB"
                     /locus_tag="AC1PIV_001639"
     CDS             complement(2526..4478)
                     /gene="gyrB"
                     /locus_tag="AC1PIV_001639"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HIP6612647.1"
                     /translation="MTEEIKDLQEKAQEYDASQIQVLEGLEAVRMRPGMYIGSTSKEG
                     LHHLVWEIVDNSIDEALAGFADKIEVYIEPDNSITVIDNGRGIPVDIQEKTGRPAVET
                     VFTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVYKNGQVYFQEYKRGEVV
                     ADLEVVGETDRSGTTVHFTPDPEIFTETTEFDFAKLNKRIQELAFLNRGLNLSITDKR
                     EGVEQTKEYHYEGGIASYVEYLNENKDVIFETPIYTEGEMDDITVEVAMQYTTSYHEN
                     VVSFANNIHTHEGGTHEQGFRTALTRVINDYAKKNKILKENEDNLTGEDVREGLTAVI
                     SVKHPGPQFEGQTKTKLGNSEVVKITNRLFSDAFAEFLLENPQIARRIVEKGILASKA
                     RIAAKRAREVTRKKSGLEISNLPGKLADCSSNDAAKTELFIVEGDSAGGSAKSGRDRE
                     FQAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGADFDVSKARYQKLVIMTD
                     ADVDGAHIRTLLLTLFYRYMRPVVEAGYVYIAQPPIYGIKVGSEIKEYIQPGVNQEQE
                     LQDALERHSTGRSKPTIQRYKGLGEMDDHQLWETTMNPENRLMARVSVDDAAEADKIF
                     DMLMGDKVEPRREFIEENAVYSTLDV"
     gene            complement(4660..5199)
                     /locus_tag="AC1PIV_001640"
     CDS             complement(4660..5199)
                     /locus_tag="AC1PIV_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1 family glyoxalase III"
                     /protein_id="HIP6612648.1"
                     /translation="MTRVAVVLADGFEEIEALASVDVFRRAHFDCQIVGLDSHEVEGS
                     HGIRVQTDQVFDGDLSSFDLIVLPGGMPGSVHLRDSESLITELQRAVASGKSVAAICA
                     APIVLDKAGLLDSRHYTCFPGKEKDIPSGIHLEEDVVVDGPIITSRGAGTSLDFAYKL
                     VDLFGGDGESLAQTMVYHS"
     gene            complement(5213..6442)
                     /locus_tag="AC1PIV_001641"
     CDS             complement(5213..6442)
                     /locus_tag="AC1PIV_001641"
                     /EC_number="2.4.99.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008955 - peptidoglycan
                     glycosyltransferase activity [Evidence IEA];
                     GO_function: GO:0015648 - lipid-linked peptidoglycan
                     transporter activity [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HIP6612649.1"
                     /translation="MRKLMKNRGTIDSRVDYSLILPVFFLLVVGIISLYIAVSQDYPD
                     NVVQMVGQQIAWIGIGTVAAFLVMFFSTKFLWQITPYLYVLGLGLMVLPLFFYSPDLV
                     ASTGAKNWVTIGGMTLFQPSEFMKIAYIIMLSRVIVTFHKYYPNRKIREDFMLIGYMT
                     LFTIPVLILLALQKDLGTSLVFVAIFSGMLLLSGVSWKILLPTALTGIVLVGGFMLIF
                     ISPGGTTFLHNLGMDTYKINRIAAWLDPFKNAQSTTYQQAQSLIAIGSGGLKGLGFNK
                     TNLLIPVRESDMIFTVIGEDFGFIGGTVLIGLYLLLIYRMLRVTLKSNNRYYTYISTG
                     YIMMLLFHVFENVGAATGLLPLTGIPLPFISQGGSSMVSNLIGVGLVLSMGYQSRLAD
                     EKETNRSRRYRKITIKR"
     gene            complement(6891..7133)
                     /locus_tag="AC1PIV_001642"
     CDS             complement(6891..7133)
                     /locus_tag="AC1PIV_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HIP6612650.1"
                     /translation="MKKDIHPEYRTVVFMDTTTGYKFLSGSTKKSNETVEFEGETYPL
                     IRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
BASE COUNT         2158 a         1630 c         1201 g         2208 t
ORIGIN      
        1 ttagtcgagt tctttcccgc tcccattatt tactatctaa aatctctatt agtttataga
       61 gatttttttc atttatttgg tagggcacct gttcttggac aatcggttta gcacagaaag
      121 ctactccaat tcctgctcgt tgaatcattg gtagatcatt tgctccatcc cccatggcaa
      181 tcgtttgaga tagactcagc ccattttctg ccgcccattc ttctaaacat gcttttttag
      241 tatctttcgt tacaatttca cccaacactt gtcccgtcaa tactccatct actacttcta
      301 atcgattagc ccgaacatag tctaactcta actgtgcagc tagtcgatca actgtttcat
      361 gaaacccgcc tgaaacgact gctaccttat agcctcgcat ttttaattct gagactaatt
      421 ctgctgctcc aggcgtaaag tggatttttt tgataattcg atcaaacaca gaaacaggca
      481 atccctttaa caacgccaca cgttcacgta aggcttcttc aaaatccaat tccccacgca
      541 tagcacgttc ggtaattgct gcaacttgcg ctcctaaacc ggcctcttct ccaagtaaat
      601 ctattccttc ttccaaaatt aatgttgaat caacatccat aactaataat ccagttgtca
      661 tctccaatat tcctttcaat gtataaaaat aaaaagccaa atggcttttt atctagtagc
      721 gaatggcttc gcgagttttt tcgtatgaac gcacaaaacg ctctgttaca ccaggttcaa
      781 ctgtttccag agcaaatgaa atttcttcaa atgctgcttg gtaatcaaaa tccttttcaa
      841 aaattgataa tgaacggtta aatgcttttt gcacactttc atcgaatgaa cgataacggt
      901 tagagtattg tagcaactgc tctgtcaaag tcgcattttg cacaatcaaa tacgccaact
      961 cttccaattg attcatatca tacgttgcat tttccaacaa acggttaaca acttcgatat
     1021 tgattcgttt atagtctaac tcggcaatca aggcttccac atgatcgctc gttctaaaga
     1081 agtttgttaa aaattcagct ggaattcctg gaaggttgcg tttttccata taacgcttaa
     1141 gggtatgcaa tttgttgata taaagtgtag ctttcttacg cgctgtgttc tctgacaatt
     1201 cttgtgattt aagatagtca gctaaaacaa gctgctcctc ttcgatttct ttcaagcttg
     1261 ccaatgaatg atccaaacgc tcttctaaaa tagaatatgc aacttgtgga ttttcaatgt
     1321 cttccacact ttctgtaaca acaatctcaa tcgattccaa acgagcttta agctgattga
     1381 tacgtgaaag tttgctatct gccagcaagt aagttgcatt taggcgttgg ctttcctcat
     1441 ccaagagctg tgtattttgg acaacatgct ccaagaattt tggcaagttt ttactaatct
     1501 taacagcttc cttattcgct tcgatttcac gattgaagac tttatacaaa tgatcaattt
     1561 ttgcttgaat tccctcattt tcagcttctg cggcatccaa atcaaaggaa acaatcaaag
     1621 cagtattttc acgaattgaa acgcgaatat tttggaactg tgactcgatg ttagcttctg
     1681 tgaacaaata attctgctca accagtttac gataacccga ctccaaatct tccaattgct
     1741 ctgggaaatc ttttgtaact cgttcaatca aacttggaat gcgatccatg atttgattga
     1801 gggcaatcat atgctcttca gtcttatcaa ggatttcaga agcttcaatc gggtcacctg
     1861 aggaattaag catcacaaat tcagaaaact caacttcaat atttttcaat tgtttctcaa
     1921 gttctgatag tgtctcaccg tagctatctg gattttcacg aacagcttcc tgtaaactat
     1981 cgaacaagtt taacgcatgt tttacgcgac cagagttttt ctcttcttgc tccttcaact
     2041 ccatcaaacc ttgacggata gaggcaatat cttcttcaat taaatcaatt tggctgtcga
     2101 tactgtcgat agcgttcttt gcactcacaa agcgaaaggc attgttatag ccttctgcct
     2161 caaagatatg attttcaata tcggcaaatg aattgagcga caaatcaacc catttttgat
     2221 tccattcacg gaatgacacc tgactttgac caatcaaatg aagtgctttg acagtttcga
     2281 cttcttcatt aactggaagg ttaaatagct cttccttacg ttcttccaat gcaaccaaaa
     2341 ggttgtcatt tcgtttacga acaatcaggc aagctacata ggcaatgatt aaaataataa
     2401 caatcgaaac gattaagatg attgttcctg taggcatgta aatctcctta gctcatagta
     2461 attactagaa aatatcgctt aattatacca taaatctcta gtatatgcac ttgttttttt
     2521 agtttttaga catccaatgt tgaataaaca gcattttcct cgataaactc tcgacgaggt
     2581 tcaaccttat cccccattaa catgtcaaaa atcttatcgg cttctgccgc atcatcaact
     2641 gaaacgcgtg ccatgagacg attttcagga ttcatcgtag tttcccacaa ctgatgatca
     2701 tccatttctc ccaaaccttt gtaacgttga atcgttggct tggaccgtcc cgtactatgt
     2761 ctttctaagg catcttgcaa ttcttgctct tgattaaccc caggttgaat atattctttt
     2821 atctcacttc caaccttgat accgtaaata ggtggttgag cgatatatac gtatcccgct
     2881 tctacaacag gacgcatgta gcggtaaaat aatgtcagaa ggagtgtccg aatatgggca
     2941 ccatcgacat cggcatctgt cataatgact aatttttgat aacgtgcctt gctaacgtcg
     3001 aaatcagcac caaagccagt tcccatagct gtaaatagac tacggatttc ttcgttggcc
     3061 aaaatcttgt ccatgctggc tttttctacg ttcaaaatct taccacgaat cggtaaaata
     3121 gcctgaaatt cgcggtcgcg accggattta gctgaaccac cggctgagtc cccctcaacg
     3181 atgaaaagct ctgtcttcgc tgcatcattt gaggaacaat ccgctaactt acctgggagg
     3241 tttgaaatct caagacccga tttcttacga gttacctcac gcgcacgctt agcagcaata
     3301 cgagccttgc ttgccaaaat acctttttca acaatccgtc tagcaatctg tggattttcc
     3361 aaaagaaatt ctgcaaaggc atcagagaaa aggcggttgg taattttgac cacttcacta
     3421 ttcccaagtt ttgtcttagt ttgtccctca aattgaggac ctgggtgctt aacagaaatg
     3481 accgctgtca aaccttcacg cacatcttca ccagtcaaat tatcctcatt ttctttgaga
     3541 attttatttt tcttggcgta gtcgttgata acacgtgtca gagctgtacg gaatccttgc
     3601 tcatgggtac caccttcatg tgtgtgaata ttgttggcaa aactaactac gttttcatga
     3661 taactcgtcg tatattgcat ggcaacctca acggtaatat catccatttc accttctgta
     3721 tagatagggg tctcaaaaat gacatccttg ttctcattaa gatactcaac gtaggaagca
     3781 ataccacctt catagtgata ttcctttgtt tgctctactc cctcacgttt gtccgtaata
     3841 gagagattta aaccacgatt taggaaggcc aattcttgga tccgcttatt taattttgca
     3901 aagtcgaact cagtcgtctc agtaaaaatt tctggatcag gtgtaaaatg tacagttgta
     3961 ccagaacggt ctgtttctcc aacaacctcc aaatctgcaa cgacttcacc tcgtttatac
     4021 tcttggaaat atacctgacc atttttgtag acatggacgt ctagctgagt agatagggcg
     4081 tttacgactg atgaacctac gccgtgcaat ccacctgaga ccttataacc gcctccgcca
     4141 aatttaccac ctgcatggag cactgtaaag acagtttcta ccgctggacg accagttttt
     4201 tcctgaatat ctaccggaat cccacgtcca ttatcaataa ccgtgatgga gttatctggc
     4261 tcaatataaa cttcaatttt atccgcaaaa ccagccagcg cctcatcgat tgagttgtcg
     4321 acaatttccc aaaccaagtg atggagacct tctttagatg ttgagccgat atacatccct
     4381 ggacgcattc gaacagcttc aagaccttcc aagacttgaa tctgactggc atcatattct
     4441 tgagccttct cttgtaaatc tttgatttct tctgtcattt cttttcctta ttttctattt
     4501 gttgctcctt aaaaatagaa aagccaatcc atctggataa aagcgaaaca tatttttaga
     4561 gcaaaaatca ttctaacgaa taccctttat tataccatat tttctaatat tttgatagaa
     4621 aaaagaagag gaaacattag ctccatcttc ttcattactt taactatgat aaaccattgt
     4681 ttgagctagg ctttccccat ctccaccaaa taaatcaacc aatttatagg cgaaatccaa
     4741 acttgttcca gcacctcggc tagtgataat tggaccatca acgaccacat cctcttccag
     4801 atgaatacct gacggaatgt ctttttcttt ccctgggaaa catgtatagt gacgactatc
     4861 taacaaacca gccttatcca gaacaattgg tgccgcacaa attgctgcta ctgattttcc
     4921 tgatgcaacc gctctttgca attccgtaat cagtgactct gaatctctaa ggtgaacaga
     4981 acctggcatt cctcctggta aaacaatcag atcaaaggaa gacaggtccc catcaaagac
     5041 ttggtcagtt tgaacacgaa taccgtgcga tccctccact tcatgactat ctaaaccaac
     5101 aatctgacag tcaaaatgag ctcgacggaa tacatctaca gaggccaatg cttcgatttc
     5161 ttcaaaacca tcggctaaaa caaccgcaac tcttgtcata taaaccaact ttctaacgtt
     5221 ttatcgtaat ttttctatag cgacgtgatc gatttgtttc cttctcatca gctagtcgtg
     5281 actgataccc cattgacagc actagaccaa caccaatcag atttgaaacc atggacgagc
     5341 caccttggga gataaacggc aaaggaatac ctgttaaagg taacaaacca gttgcagcgc
     5401 caacattttc aaacacatgg aacaagagca tcatgatata gccagttgat atgtaggtgt
     5461 agtatcgatt gtttgacttc aacgttaccc gcagcattcg ataaatgagc aacaagtata
     5521 gtccaatcaa taccgtccca ccaataaaac caaagtcctc tccaatcacc gtaaaaatca
     5581 tatcactttc tcgaacaggt ataagaagat ttgttttatt gaaacctagt ccttttaagc
     5641 caccacttcc gatagctatc aaactttgag cttgctggta ggtcgttgat tgggcatttt
     5701 taaagggatc aagccaggct gcaatacgat tgattttata agtatccatc cccaaattgt
     5761 ggagaaatgt tgttccacca ggagaaataa aaatcagcat aaatccgcca accaaaacga
     5821 tacctgttaa ggcagtcggt aatagaattt tccaagaaac tcctgataat agaagcattc
     5881 cgctaaagat tgctacaaat actaaggaag ttcctaaatc tttctgtaag gccaacaaaa
     5941 tcaggacagg gatagtaaac agtgtcatat aaccaatcaa cataaaatcc tcacgaattt
     6001 ttcgatttgg ataatattta tgaaaggtga caatcaccct tgacaacata atgatgtagg
     6061 ctattttcat aaattcggat ggttgaaaaa gagtcattcc accaatcgtt acccagtttt
     6121 ttgctcccgt tgatgctact aagtctggac tgtagaaaaa caaaggcaat accataagtc
     6181 ctagcccaag tacgtacaag taaggtgtga tttgccacag aaacttagtg gaaaagaaca
     6241 tgaccaaaaa agctgccact gttccaattc ctatccaagc aatttgttga ccaaccatct
     6301 gtacaacatt atccggataa tcttgactaa ccgcaatgta gagagaaata atccccacaa
     6361 ctaataaaaa aaagaccggt aaaataagtg agtagtctac tcgactatcg attgttcccc
     6421 tatttttcat caatttcctc atactttcac ttcaaattct tactcgttcc attatagcag
     6481 aaatcatctc tcattgaaac taaaaatcta gttacatcag tggggatacg atttatactc
     6541 aacgaaaatc aaaagtagcc taggaaacga agtcgaagat agaactggag ttcatccagg
     6601 caagttgaca acggataatt ttgattttcg aagagtatta ctagtgcaca aatcataaaa
     6661 tacgtatatc ttcatacctt cgaacaggct gaaatataat gctttacctt cacacacccc
     6721 ataagtttgc tcaattcatg agtatgtaga ccaatggcaa tcattttggc aatcacgcac
     6781 gaaaaagccc tctcttattt ctagagtcaa agaaaaaatg gtccactgga ccataactcg
     6841 ctcttttatt ttcaagctcg tgaaaaaaca gtccgttaag gactgttttt ttatttgaga
     6901 ccgtattttt tgttgaagcg atccacacgt ccatctgctt gagtgaactt ttgacgtcca
     6961 gtatagaatg ggtgtgagtc tgatgaaatt tccacacgga tcaatgggta agtttcacct
     7021 tcgaattcaa ctgtttcgtt agatttctta gttgaaccgc taaggaactt gtagccagta
     7081 gttgtgtcca tgaagacaac agtgcgatat tctggatgga tatctttttt cattttaaaa
     7141 ttcctttctg ccatggactc tttccgagcc atagattata accatttaag tttacca
//
LOCUS       DBNFCO010000079         7077 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.079, whole genome shotgun sequence.
ACCESSION   DBNFCO010000079 DBNFCO010000000
VERSION     DBNFCO010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 7077)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7077)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7077
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.079"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            272..604
                     /locus_tag="AC1PIV_001643"
                     /pseudo
     CDS             272..604
                     /locus_tag="AC1PIV_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638881.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(652..2190)
                     /locus_tag="AC1PIV_001644"
     CDS             complement(652..2190)
                     /locus_tag="AC1PIV_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HIP6612651.1"
                     /translation="MENHRKEVSFISQSILYSVLRGSLVGIVAGLVVVAFRLAIEKLF
                     SVFTHLYSLATDNAIYLLLIGGLYLVIALLVGKLIKDEPNAKGSGIPQVEAELKGIMD
                     LNWWSVLWRKFIGGVLSIASGLMLGREGPSIQLGAVTAKGVSVLLKSSEMERRSLIAS
                     GAAAGLAAAFNAPIAGLLFVVEEVYHQFSRLVWVSALAASITANFISLHVFGLMPVLH
                     MPKDLQLLSLDQYWIYILLGVFLGLAGYVYEIVILNIQDFYTLLSKIIPLPVPYYSVF
                     AFLFIIPIGYFFPNLLGGGHHLILELPYLEQGLLTLAILILIRFVWSMISYGSGLPGG
                     IFLPILTLGSLLGLFVARFFLDIGFISQEQMLLFIVLGMAGFFAAISKAPLTAIILVT
                     EMVGSLNQLMVIGLVALSSYVMMDLLGGAPVYEAMLEKILPEEVEQQEHMTLIEVVVN
                     ETLDRRFVSELRLPDSCLITSQIHHGKSRIVKGNSQLSMGDSLLVAVPISQIHTVRRI
                     FEGD"
     gene            complement(2304..3374)
                     /locus_tag="AC1PIV_001645"
     CDS             complement(2304..3374)
                     /locus_tag="AC1PIV_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HIP6612652.1"
                     /translation="MKRLYSFFVGIIAIVLVLWGISYKLEADSTQGTTDKLVIYNWGD
                     YIDPELLAEFTAETGIQVDYQTFDSNESMYTKIKQGGTTYDLTIPSEYMISKMTEENM
                     LIKLDKSKIEGIENIDPRFMGLSFDKNNDYSIPYFWGTLGIVYNETMVENPPQEWEDL
                     WSEEYRDNIMLIDGVREVMGFGLQSLGYSLNSNNPTEIEKAAEHLYNLTPNVKAIVAD
                     EIKGYMIQDAAAIAVSFSGEASEMLDGNENLRYVVPSKGSNLWFDNMVIPKTAKNIDG
                     AYAFMSFMLRPENALRNAEYVGYSTPIPAAKAMLDEETQNDESFYPSEETMKKMEVYD
                     NLGPEMLGMYNDLYLQFKMYRK"
     gene            complement(3374..4144)
                     /locus_tag="AC1PIV_001646"
     CDS             complement(3374..4144)
                     /locus_tag="AC1PIV_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIP6612653.1"
                     /translation="MKKFANIYLTVAFLLLYLPIFYLIFYAFNEGGDMNGFTGFTLEH
                     FSSMLGDSRLMLILAQTFLLAFLSSLIATIIGTFGAIYIYQAKPRFQNALLSVNNILM
                     VAPDVMIGASFLILFTMIGFQLGFVSVLLSHIASSIPIVVLMVLPRLKEMNADMISAA
                     YDLGATQPQMLKEIMLPYLTPAIIAGYFMAFTYSLDDFAVTFFVTGNGYSNLSVEIYS
                     RARQGISLEINALSTLVFLFSILLVVGYYFISREKEAN"
     gene            complement(4144..4944)
                     /locus_tag="AC1PIV_001647"
     CDS             complement(4144..4944)
                     /locus_tag="AC1PIV_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIP6612654.1"
                     /translation="MKKTSRLFAIPYALWVFLFVLAPVALIIFKSFFDIHGDFTLANY
                     QTYFNSPNMTYLRMSFNSIFYAGIITLVTLLVSYPTAYFLTKLKHRQLWLMLIILPTW
                     VNLLLKAYAFIGIFGQHGSINQFLEFIGLGAQQILFTDFSFIAVAAYIEIPFMILPIF
                     NALDDLDKNLINASRDLGATPWQTFTKVIFPLSMNGVRSGVQAVFIPSLSLFMLTRLI
                     GGNRVITLGTAIEQHFLTTQNWGMGSTIGVVLILAMLLIMWMTKERKK"
     gene            complement(4928..6082)
                     /locus_tag="AC1PIV_001648"
     CDS             complement(4928..6082)
                     /locus_tag="AC1PIV_001648"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000184097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIP6612655.1"
                     /translation="MKKPIIEFKNVSKVFEDSGTTVLKDISFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDASSGDIYLDGQRINDVPTNKRDVHTVFQSYALFPHMTVFENVAF
                     PLKLRKIDKAEIERRVTEALQMVRLSGYENRSIQKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTEMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNEGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGRMIEDYLVEFNGKRFEAVDGGMRPNEEVEV
                     VIRPEDLQITLPEEGKLQVKVDTQLFRGVHYEIIAYDDLGNEWMIHSTRKAIVGEVIG
                     LSFEPEDIHIMRLNETEEEFDARIEEYVEVEEVEDGLINAIEEERNEENL"
     gene            complement(6121..7029)
                     /gene="murB"
                     /locus_tag="AC1PIV_001649"
     CDS             complement(6121..7029)
                     /gene="murB"
                     /locus_tag="AC1PIV_001649"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HIP6612656.1"
                     /translation="MKDKIRLELEGIDIRFDEPLKEYTYTKVGGAVDYLAFPRNRYEI
                     VRIVEFAKREGIPWQVLGNSSNIIVRDGGIRGFVIRMDKLNSVTVSGYTIEAEAGANL
                     IETTKVALFHSLSGFEFACGIPGSIGGAVYMNAGAYGGEVAHILVSAQILTPAGYVET
                     LDNRELRFGYRSSILQENGAIVLSAKFALRPGNHTVIQQEMARLTHLRELKQPLEYPS
                     CGSVFKRPLGHFAGQLIMDAGLKGYRIGGVEVSEKHAGFMVNIENGTASDYENLIAHV
                     IQVVEKSSGITLEREVRIIGDPADTL"
BASE COUNT         2254 a         1536 c         1338 g         1949 t
ORIGIN      
        1 gacatccatg atggctccgt ccttacccac agaataatga gaatgagcat aaagccctca
       61 ctaagattat atacctagtg agggccttgt ggttggtgca ttattgatgt taattatgat
      121 gacaaaactg ctccacccta ctgataagaa ccacaatatg cgctcaagaa tatgactaaa
      181 attcagtaga taggctctct aattttaaga aggaaagaat tgtcatagta atcatgtgta
      241 gatcaagtcg atattgtcgt ttgtattccc ctcaacttgt ccaaagcgtt acttagctac
      301 atttgataca acgactaaag gtctacgtgc ttaccacgat tttctcagtc aatttcatgt
      361 agaagctgtt ggtatggaaa gcacaggtgt ctattggcga cttgtctggc atgctctatg
      421 tgatgacttc gagctaatac ttgctcaacc agcccacatg aaggctattc caggtcagaa
      481 aaccgacaag aaggacgctc actggattgc caaattaaca cggattggtc tgcttcctcg
      541 gagtttcgtt cccgatgaaa ccattcaaga attgagggag ttgaccagac aacgaaaaca
      601 gtataatatt gggacttttc tcatctcttt gttaagacaa tctaaaaaat gctaatctcc
      661 ctcaaatatc ctacgaacgg tatgaatttg agagattgga actgcaacga gcaaggaatc
      721 ccccatagaa agttggctat ttcctttcac aatccttgac ttaccgtgat gaatttgact
      781 ggtgatcaag catgaatccg gcaaacgtaa ctcgctaaca aatcttctgt ccaatgtttc
      841 gttgacaaca acctctatta aggtcatgtg ttcttgctgt tctacttctt ctggcagaat
      901 tttttccaac attgcttcat agactggcgc gccacctaag aggtccatca tcacatagga
      961 actcaaagct accaacccga tgaccatcaa ttggttcaaa cttccaacca tttcagttac
     1021 taaaataata gcagttagag gtgctttgga aatcgctgcg aaaaagcctg ccattcccaa
     1081 tacaataaac aatagcatct gctcctgact gatgaaacca atatcaagga agaaccgtgc
     1141 gacaaaaagc ccaaggagac ttcctaaggt taatatgggt aaaaagatgc cccctggtag
     1201 accagaacca taggaaatca tgctccatac aaatcgtatt aaaatcaaga ttgccaatgt
     1261 cagtagtcct tgttccaaat atggaagctc taaaatcaaa tgatgcccgc cacccaacag
     1321 attagggaaa aaataaccaa tcggtataat aaacaaaaag gcaaatacac tgtagtatgg
     1381 aactgggaga ggaatgattt ttgagaggag ggtatagaaa tcttgtatat tgaggataac
     1441 aatttcatac acatatccag caaggccaag gaaaactcca agtaagatat agatccaata
     1501 ttggtcaaga gatagtaact gtaagtcctt cggcatatgc aaaacaggca ttaatccaaa
     1561 aacatgtaag gaaataaagt tcgcagtgat actggctgcc agggcggaga cccataccag
     1621 acgtgaaaac tgatgataga cttcctccac aacaaataaa aggcctgcta ttggtgcatt
     1681 gaaagctgct gccaaacctg ccgcagcgcc actagcaatc aaactccttc tttccatttc
     1741 actggattta agaagaactg atacaccttt agccgttaca gctcctaatt gaatactggg
     1801 accttcacgc cccagcatta gaccagatgc aatggataaa acaccgccga taaattttct
     1861 ccaaaggact gaccaccagt tcaaatccat aattcctttt agttctgcct ccacctgagg
     1921 tataccagaa ccttttgcat ttggctcgtc tttgatcaac ttgccaacaa gtaaagctat
     1981 gaccagataa agccctccaa taagaagtaa atagattgca ttgtctgttg ccagagaata
     2041 gaggtgcgta aagacagaaa atagtttttc aatggctaag cgaaatgcaa cgaccactaa
     2101 accagcgaca atgccaacta aactaccacg cagaaccgaa tagaggattg attgagaaat
     2161 aaaactaact tctttccggt gattttccat tgggatttcc cttcctttct atagtatgca
     2221 tgaccaaaaa ataggagcaa taagtactta gtaaagaacc tcactcccat tcttttattt
     2281 atattgctac ctgtccaatc agactatttc cgatacatct tgaattggag atagaggtca
     2341 ttatacattc caagcatctc tggtccaaga ttatcataaa cttccatctt cttcatcgtt
     2401 tcttctgaag gatagaagga ttcgtcgttc tgagtctcct catccagcat agccttggct
     2461 gcaggaattg gtgttgagta gccaacatat tctgcattgc gaagcgcatt ttcaggacga
     2521 agcataaaac tcataaaggc gtaagctcca tcaatatttt ttgctgtttt tggaatgacc
     2581 atgttatcaa accacaggtt agaacctttt gatggtacaa catagcgcag attttcattt
     2641 ccatctaaca tttcactcgc ctcacctgag aaagaaacag caattgctgc cgcatcttgt
     2701 atcatataac cttttatctc atcagcaaca attgctttga catttggagt taaattataa
     2761 agatgttcgg ctgccttttc aatctcggta ggattgttag aattgagact atagcccagt
     2821 gattgtagac caaagcccat gacttcacgc acaccatcaa ttaacatgat attgtcacgg
     2881 tattcctctg accacaagtc ttcccattcc tgaggaggat tttctaccat ggtttcattg
     2941 taaacaatgc ccaaggttcc ccagaaatat ggaatagaat agtcattatt cttatcaaag
     3001 ctaaggccca taaatcgtgg atcgatattt tctatccctt caatcttaga cttatctagc
     3061 ttgattaaca tattttcttc tgtcatctta gaaatcatgt actcagatgg gattgtcaaa
     3121 tcgtatgttg ttccaccctg cttaatcttt gtgtacatcg attcgttgga gtcaaaggtc
     3181 tgataatcta cctgaatacc tgtttcagca gtgaattctg cgagtaattc tgggtcaata
     3241 taatcgcccc agttatagat gacaagttta tcagttgtcc cttgggttga atcagcttct
     3301 aacttataac taattcccca taaaactagg acaattgcta taattcctac aaaaaatgaa
     3361 tacaatcgtt tcattagttg gcctcctttt cacgtgagat gaaataataa cccactacca
     3421 ataagataga gaaaaggaaa actagggttg acaaggcatt gatttctaga gaaatccctt
     3481 gacgagcccg tgagtaaatc tctacagata ggtttgagta accatttccc gtaacaaaga
     3541 atgtcacggc aaagtcatcc aaggaatagg taaaggccat aaagtagcct gcaatgatgg
     3601 ctggtgttag gtatggcaac atgatttctt tcagcatttg tggctgagtt gcccccaaat
     3661 cataagctgc tgaaatcata tctgcgttca tctctttcag ccgtggcaag accatcaata
     3721 ctacgattgg aatagaagaa gcaatatgac tgagcaatac tgagacaaag ccaagctgga
     3781 aaccaatcat ggtaaagaga attaggaaac tcgccccaat catgacgtct ggagctacca
     3841 tcaagatatt attgacagac aagagtgcat tttgaaaacg aggttttgcc tgatagatat
     3901 agatggcacc gaaagttccg ataatggtcg caatcaaaga actcaagaag gccaacaaga
     3961 aggtttgagc cagaatcagc attagtcggc tatcgccaag catagatgaa aaatgctcta
     4021 aggtaaagcc tgtaaagcca ttcatatctc cgccttcatt aaaggcataa aaaataagat
     4081 agaaaatcgg taagtagaga aggagaaagg caactgttaa gtagatattt gcaaatttct
     4141 tcattatttc ttcctctctt tcgtcatcca cataatcaag agcatggcca aaatcaagac
     4201 cacacctatg gttgaaccca ttccccagtt ttgtgttgtg agaaagtgtt gttcgatagc
     4261 tgtaccaagc gtgatcactc ggttgccgcc aatcaaacgg gtcaacatga agaggctcag
     4321 acttggaatg aaaaccgcct gtacaccaga acggacacca ttcatagaaa gaggaaaaat
     4381 aacttttgtg aaggtctgcc aaggagttgc ccccaaatca cgactggcat tgattaggtt
     4441 tttatccaaa tcatccaagg cgttaaagat cggcaaaatc ataaacggaa tctcaatata
     4501 ggctgcaaca gcaataaagg agaaatctgt gaaaagaatt tgctgagctc ctagaccaat
     4561 aaattctagg aactggttga tagagccgtg ttgtccaaaa ataccgataa aggcataggc
     4621 tttcagcaaa agattgaccc aggttggcaa gataatcaac atgagccaga gctgtctatg
     4681 cttgagtttg gtcaagaaat aggctgttgg gtaggaaacc aaaagcgtga ccagagtaat
     4741 aatacctgcg taaaaaatgg agttaaaact cattcgcaga taggtcatat ttggcgagtt
     4801 aaaataggtc tggtaattgg ccaaagtgaa atcgccatga atatcaaaga aagatttgaa
     4861 gataatcaag gcaactggag cgagtacaaa tagaaagacc catagggcat agggaattgc
     4921 aaaaagccta gaggttttct tcattgcgtt cctcctcaat ggcgttaatc aagccatctt
     4981 ctacttcttc cacttccaca tattcttcga tacgggcatc gaattcttcc tctgtttcat
     5041 tgagacgcat gatatgaata tcttctggct caaaacttag tccaatcact tctccgacaa
     5101 tggccttacg agttgagtga atcatccact cattaccgag gtcgtcatag gcgatgattt
     5161 catagtgaac ccctcggaag agctgagtat ccacttttac ctgcaatttg ccttcctcag
     5221 gtagggtaat ctgcaaatct tctggacgga taacgacttc aacttcttca ttaggacgca
     5281 taccgccatc gacagcttca aagcgtttgc cgttaaactc aaccagatag tcttctatca
     5341 tgcgacctgg aaggatattg gattcaccga tgaaggtagc aacaaaatgg ttgattggtt
     5401 cgtcgtaaat gtccactggc gtcccagact gaacaatttc accttcattc atgacaaaaa
     5461 tccagtcact catggccaga gcttcttctt ggtcatgggt aacgaagacg aaggtaattc
     5521 ctagacgttg ttgcaattca cgcagttcgt actgcatttc tgttcttagt ttcaagtcca
     5581 gggcagaaag tggttcatct agcaagacaa cgcgaggctg gttgataatc gcacgtgcaa
     5641 tagcaacccg ctggcgttga ccaccagaca atttctgaat ggaacgattt tcataaccag
     5701 aaagtcggac catttgtaag gcttctgtca cacggcgttc aatttcagcc ttgtcaatct
     5761 ttcgtaattt aagaggaaaa gccacatttt caaagacagt catatgtggg aaaagggcat
     5821 aggactggaa aacagtatgg acatcccgtt tattggtcgg aacatcatta atccgttgac
     5881 cgtccagata aatatcacct gaactagcat ccaataaacc agcaataata ttcaaaatcg
     5941 ttgatttacc tgaaccagaa gctcctaaaa gggtataaaa tttcccctct tccaattcaa
     6001 aactaatatc ctttaataca gttgttccac tgtcttcaaa tacttttgaa acgttcttaa
     6061 attcaataat tggctttttc aattctcata aattccttct tttttgtaag agcctgatgg
     6121 ctagagtgta tcagcaggat cgccgataat acgaacctct ctctccagag taattcctga
     6181 agatttttca acaacttgaa tcacatgggc aatcaaattt tcgtaatcag atgctgtacc
     6241 attttctata ttgaccataa agccagcgtg tttttcagaa acttcgactc caccaattcg
     6301 ataacctttt aaacccgcat ccataatcaa ctgtcctgcg aagtgaccaa gtggacgctt
     6361 gaagactgaa ccacaagatg gatattccaa aggttgcttg agctcgcgca aatgtgtcaa
     6421 acgagccatt tcttgttgaa taaccgtatg atttcctggc ctgagggcaa attttgcaga
     6481 caaaacaatc gcaccgtttt cctgcaaaat agaagaacgg tagccaaatc gtaactcacg
     6541 attgtccaat gtctcgacat aacctgcagg agtcaaaatc tgcgctgaaa ctaaaatgtg
     6601 tgccacttca cctccgtaag cacctgcatt catatagaca gcaccaccaa tgcttcccgg
     6661 aataccacaa gcaaattcaa atcctgataa cgaatggaaa agtgcgactt ttgttgtttc
     6721 aatcagattg gcacctgctt ctgcttcaat ggtgtatcct gatacagtaa cggagttaag
     6781 tttatccata cggataacaa aaccacgaat accgccatcg cggacaatga tattacttga
     6841 atttcctaat acttgccatg gaataccttc gcgtttagca aattctacta tacgaacaat
     6901 ctcgtaacga ttccgcggaa aagctagata atcaacagct cctcctactt ttgtataggt
     6961 atattctttt aaaggttcat cgaatcgaat atcgatgcct tctaattcaa gcctaatttt
     7021 atctttcata accttctcat ttcaatttaa gatatacagg atttattata ccaaaaa
//
LOCUS       DBNFCO010000080         7074 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.080, whole genome shotgun sequence.
ACCESSION   DBNFCO010000080 DBNFCO010000000
VERSION     DBNFCO010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 7074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7074
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.080"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(17..2026)
                     /locus_tag="AC1PIV_001650"
     CDS             complement(17..2026)
                     /locus_tag="AC1PIV_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIP6612657.1"
                     /translation="MFGLTVRLALTNLKKNRRLYFPYALMTILSTAIAYIFASLAFHP
                     DLGQVKGANGVIQVLGFGMIVVMLAVAIMVFYANSFVMKQRSKEFGVYSILGLEKKHL
                     FLMTFLENLVFSVGTILAGLLLGLALDKLFYALLLKAMQMPVVLASTFQLKSLVTVFI
                     YLFGIFALVSLFNIGNLGLTDSLKLVQGKKRGDKKTGFLWLQTLLVLILLGAGYAIAQ
                     LVTSPMQAIPSFFGATLLVIFGTYLLFHAGVISLLNWLKNRQTYYYKPDNFISVSNLI
                     FRMRKNALGLATITILSSMFLVTMVGGLNIYIGGKDYIANQNPNDYSIDVGMQPTTSK
                     AQTEKWEEWAEAILEETDIPVESKVVYPYQQAYFSEVANQQVRFLTEKESWMDFSNQV
                     GVGYILDKATYEKMTSQKLELAADQVAIYSKGVQYQAGQTLTFDEKEMEVAQVLPKNV
                     TLGHLPDHVTFNFSKYLVIVVQDLTIFENQAENRYYMGFESSLSEEEQVNSQEVFLSG
                     SFESELWESNILPNGTNAISLAYRAYAMRSFFSFAGSLFFIGLLLSLIFLMAVVLVIY
                     FKQISEGYEDRDRFVIMTKVGLDEDQTRQSIRKQLLTVFFLPILLAFVHLAFAYKMLS
                     SILLSIGVVNAGLMLQVTAGICGGYLLLYLVVYAITTRSYKQIIS"
     gene            complement(2028..2786)
                     /locus_tag="AC1PIV_001651"
     CDS             complement(2028..2786)
                     /locus_tag="AC1PIV_001651"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIP6612658.1"
                     /translation="MSVLDVQHVQKIYSSLFKAGQVEALKDIHFAVEKGEYVAIMGES
                     GSGKSTLLNILATLDKPTQGKVLLNGLDTQSIKSKEAAAFRREKLGFVFQDFNLLDTL
                     SVKDNVLLPLVLSRYPIDEMNKRLVHTLNSLGIATLQDKMPYEISGGQQQRVAVARAI
                     ITQPEILLADEPTGALDSKSTATLLDIFEKINQEGQTILMVTHSTVAASRAKRVLFIK
                     DGILYNQIYRGERTSQEMYQLISDTLTLMANRGE"
     gene            complement(2882..3874)
                     /locus_tag="AC1PIV_001652"
     CDS             complement(2882..3874)
                     /locus_tag="AC1PIV_001652"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIP6612659.1"
                     /translation="MNKDDFGSLVPVFLTSWLGHRLIFLIAYAVFAVAILAYSSLFDI
                     KRNLVFYAILLLSICWLLALLWDFVREFSRFGKIWRGQKVTTGTASERLLQEKVERLE
                     VQNKQILEKQRQEQTELDDYYTLWAHQMKTPIAASQLLVKEVDSSPVRHQLETELFKI
                     EQYTGLVLNYLRLQSFHDDLVIESVNLDELVRNLVRKYSLFFIQVNTSLDLGQLDRTV
                     KTDKRWLGLLIEQILSNALKYCQEGTISIVLDGDDLVIRDTGIGIAESDLERVFERGF
                     SGFNGRRTQQSSGLGLYLSRKIAAELGYSLKLKSKVGQGTEVRIGIKEVELIFY"
     gene            complement(3867..4550)
                     /locus_tag="AC1PIV_001653"
     CDS             complement(3867..4550)
                     /locus_tag="AC1PIV_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HIP6612660.1"
                     /translation="MQKILLIEDDKTISQLVAKNLINWGYQVQEVKDFQMVLEQMEEF
                     QPHLILLDIGLPFFNGYYWCQEIRKTSRVPIMFLSSHDQPMDIVMAINMGADDYVTKP
                     FEMTVLLAKIQGLLRRTYDFVGEQSLLWFEEISLDLKTMQVSYGQVVEELTRNEFQIL
                     RVLFEHGKEVVSREELMRELWNSDIFVDDNTLSVNIARLRKKLAELDLPDVIATKKGV
                     GYGLVWTHE"
     gene            4720..5901
                     /locus_tag="AC1PIV_001654"
     CDS             4720..5901
                     /locus_tag="AC1PIV_001654"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HIP6612661.1"
                     /translation="MPNLLTYLEETQYDNFYDKPINKLDILALTELSYLPFDNLVPYS
                     FTENGVRLDRLAAAFEETYKNNFPPFSMVTKNRLALLGLLFKSKRFKSIKAFGFVDDY
                     QLEQEKQFSAISYRIDRKTIVTCFRGTDDTIIGWKEDFHMTYMDEIPAQRAASGYLEK
                     LMMQQGGHFYLAGHSKGGNLALYAACQQATDQQDRILAIYPFDSPGLHKKHLEAPSYQ
                     AIHQRIFPVIPQNSIVGMMLETPENAQIVQSNTLGILQHISFSWEVDGSDFKIAPALT
                     SDSLQTDQALKTWTDSLTDDELRDFFDLFFGIFIKAGIERFSDITVNPLQKLQEIDRL
                     RKEIAPEEAEMVDKLIRLLFDTRYQIWRDNISTSIPSPEISLPDWRKLFQRNTTENKE
                     N"
     gene            complement(5916..7040)
                     /locus_tag="AC1PIV_001655"
     CDS             complement(5916..7040)
                     /locus_tag="AC1PIV_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HIP6612662.1"
                     /translation="MKLPRFGVEEWLNVHENSAIYDIAGVSISSLTLEELFALSGTNP
                     EDFYKKLQGTKLNYGWIEGSPAFKKSVSQLYTGVKPEQILQTNGATGANLLVLYGLIE
                     PGDHVISLYPTYQQLYDIPKSLGAEVDLWQIEEEHGWLPDLEKLRQLIRPNTKMICIN
                     NANNPTGAVMDRAYLEELAEIASEVGAYILSDEVYRSFSELDVPSIIEVYDKGIAVNS
                     LSKTYSLPGIRVGWVAANHQVTDILRDYRDYTMICAGVFDDLVAQLALAHYQEILERN
                     LRILEENLAILDQWIEEEPLVSYIRPAVVSTSFVKIAVDMPMEDFCLQLLQEYGVLLV
                     PGNRFDRDGYVRLGFACEQETLIKGLEKLSQFLRRFDKEN"
BASE COUNT         2112 a         1664 c         1393 g         1905 t
ORIGIN      
        1 ttgggttccc ccaagtttag gaaataatct gtttgtaaga tcgtgttgtg atggcataga
       61 ccactaggta gaggaggaga tagccaccac agatgcctgc agtcacctgc aacataagcc
      121 ctgcattgac cacaccgata gacaaaagaa tggacgagag catcttgtag gcaaatgcaa
      181 gatggacaaa ggcaagtagg ataggtagga aaaagacggt cagcaattgc ttgcgaatgg
      241 actgtctggt ctgatcctca tccagaccaa ccttggtcat aatgacaaag cgatctctgt
      301 cttcatagcc ttccgaaatc tgtttgaagt aaatcaccag caccaccgcc atcaaaaaaa
      361 tgagtgaaag taagaggccg atgaagaaaa gtgaacctgc aaaactgaag aaactacgca
      421 tcgcataggc acggtaggcg agactgatgg cgttcgttcc attcggtaat atattggact
      481 cccaaagctc actttcaaaa ctaccggata agaagacctc ctggctattt acctgttctt
      541 cttctgatag actgctttca aagcccatat aatagcgatt ttcggcttga ttttcaaata
      601 ttgtcaagtc ttgaacaaca ataactaaat acttactaaa attaaaagtc acatggtctg
      661 gcagatgtcc caaggtcaca ttcttgggca agacttgggc aacttccatc tccttttcat
      721 caaaggtgag ggtttgacct gcttgatact ggactccctt actataaatg gccacttggt
      781 cagctgccaa ctccagtttt tgactagtca ttttttcata tgtagcttta tccaaaatat
      841 agcctacacc tacttgatta gaaaaatcca tccatgactc tttttccgtc aaaaatctta
      901 cttgctgatt tgccacctca gaaaaatagg cttgctgata aggatagact accttacttt
      961 caacaggaat atctgtctct tctaagatag cttccgccca ctcctcccac ttctccgttt
     1021 gagcttttga agtggttggc tgcataccaa catcaatcga atagtcattt ggattttgat
     1081 tggcaatata atctttgcca ccgatgtaaa tattgagtcc tccaaccatg gtcaccaaga
     1141 acatgctgga gaggatagta atggtcgcaa gacccagtgc atttttccgc atacggaaaa
     1201 tcaagttgga tacagaaatg aaattatctg gcttataata ataggtctga cggttcttta
     1261 gccagtttaa gagactgatg acacctgcgt ggaagagcag gtaggtccca aagataacca
     1321 gaagagtcgc tccaaagaaa cttggaatag cctgcatcgg actggtcacc agctgggcaa
     1381 tggcgtagcc tgcccccaat aagataagaa ctaagagggt ttgtagccag aggaagcccg
     1441 ttttcttgtc ccctcgcttc ttaccttgaa ccagtttgag tgagtcggtc aagcccagat
     1501 ttccaatatt aaaaaggctg accaaggcaa aaatcccaaa gagatagata aatacagtga
     1561 ctagactttt caactggaag gttgaagcca ggaccacagg catctgcatg gctttcagca
     1621 agagcgcata gaagagttta tctagagcca gtcccaagag caagccagct agaatagtac
     1681 cgactgaaaa gaccagattt tctagaaaag tcatcaagaa gagatgtttt ttctccagac
     1741 caagaatgct atagacacca aactcttttg accgctgctt cataacaaaa ctattggcat
     1801 agaagaccat gatggcaacg gccagcataa ctacaatcat accgaagccc agcacttgaa
     1861 tcactccatt ggcccccttg acctgaccta aatcaggatg aaaggcaagt gaggcaaaaa
     1921 tataggcaat ggctgtggac aaaatggtca tcagggcata gggaaaatag agtctgcggt
     1981 tctttttgag attggtcaga gccaatcgaa cggttagtcc aaacatacta ctcacctcga
     2041 ttcgccataa gtgtcaaggt atctgaaatc aactgataca tttcctgact agttctctca
     2101 cctcggtaga tttgattgta gaggatgcca tccttgatga agagaacccg tttggcacga
     2161 ctagctgcta ctgtcgagtg ggttaccatc agaatcgttt gcccctcttg gttgattttt
     2221 tcaaaaatat ctagaagagt tgccgttgat ttagagtcga gggccccagt cggctcatcc
     2281 gctaagagaa tttctggctg ggtgatgatg gcacgcgcca ccgcaactcg ctgctgctga
     2341 ccacccgaaa tctcgtaggg catcttgtct tgcaaggtcg caattcccag gctattgagc
     2401 gtatgaacga gtcgcttgtt catctcatca atcggatagc gagacaaaac cagaggcaag
     2461 agcacattat ccttgacaga aagagtatcc aagagattga aatcttggaa gacaaagccc
     2521 aatttctccc gacgaaaggc tgccgcttcc ttgctcttga tagattgggt atccaatccg
     2581 ttaagcaaga ccttgccctg cgttggctta tcaagggttg ccaaaatatt gagcaaggtg
     2641 gacttaccag aacctgactc acccataata gcgacatatt cacccttttc cactgcaaaa
     2701 tgaatatcct tcaaagcttc aacctgtccc gccttaaaga gagaactgta tatcttttga
     2761 acgtgttgaa catctaaaac tgacataact tgactccttt tctttttcta ccctcattct
     2821 acacggtccc aagacaaact accatagtcc tagctttcat ttgcgtgaca gttttgtaag
     2881 attagtaaaa aatcaactcc acttctttga taccgattcg cacctctgtt ccctgaccta
     2941 cttttgattt tagctttagg gaatagccca gctccgcagc aattttccgt gagagataga
     3001 gccccagacc cgaagattgc tgggttctgc ggccattgaa acctgagaag ccacgctcaa
     3061 agacccgttc caagtcactc tctgcaatcc caattcccgt atcgcgaata accaaatcat
     3121 ctccgtccaa aacaatcgaa atggtccctt cctgacaata cttgagggca ttggataaaa
     3181 tttgctctat caacaggccc agccagcgtt tgtcggtctt tactgtccta tccaactgcc
     3241 ccaagtccaa gctagtattg acctgaatga aaaagaggga atactttctt actagatttc
     3301 tgaccagttc atccaaatta actgattcga taaccaaatc atcatgaaag gactgtaagc
     3361 ggagatagtt caagaccaga cctgtgtatt gctcaatctt gaagagttct gtttctagct
     3421 gatgacggac tggactacta tctacttcct taaccaagag ctgactggct gcaatcggcg
     3481 ttttcatctg gtgggcccag agggtgtagt agtcatctaa ttctgtctgt tcctgtcgct
     3541 gtttttctag gatttgcttg ttctggactt ctagtcgctc cactttttcc tgcaacaaac
     3601 gctcactggc tgtcccagta gtcactttct gaccacgcca gatttttcca aagcgggaaa
     3661 attccctgac aaaatcccag aggagggcga ggagccaaca aatactgagg aggaggatgg
     3721 catagaaaac caagtttctt ttgatgtcaa agaggctact ataagccaga atagccacag
     3781 caaaaacggc gtaggctatc agaaaaatca agcgatgacc aagccatgat gtcaaaaata
     3841 ctggtactaa tgagccaaaa tcatccttat tcatgtgtcc acaccaggcc gtagcctact
     3901 cctttcttgg tcgcaatcac atctggcaga tccagttctg ccaatttctt acgcaggcga
     3961 gcgatgttaa ccgacagggt attgtcatcc acaaaaatat cactgttcca gagttctctc
     4021 atcagctcct cacggctgac cacttccttg ccatgttcaa ataaaacgcg taaaatctga
     4081 aattcatttc gcgtcagctc ttccacaacc tgtccatagg acacctgcat ggtctttagg
     4141 tctagggaaa tctcctcaaa ccagagtaaa ctttgttctc cgacaaagtc ataggttctt
     4201 ctaagaagcc cctgtatttt ggccaggaga accgtcattt caaagggctt ggtcacatag
     4261 tcatccgccc ccatattgat cgccataaca atatccattg gctggtcatg ggaagacaga
     4321 aacataatgg gcacacggga tgtcttgcga atttcctgac accagtaata gccattgaaa
     4381 aacggcagac caatatccag taaaatcaaa tggggctgaa actcttccat ctgttccaaa
     4441 accatctgaa aatccttgac ctcttgcacc tggtaacccc agtttatcaa gtttttagca
     4501 actagttggc taatcgtttt atcatcctcg ataagaagaa ttttctgcat aactatctcc
     4561 tttcatatcc ctactattta ttatagctta cattggaaca aatttgagta tttttataca
     4621 tttacacaag aagtagacta taaaaccagg tcatcagtgg tgcagatttg tcagaccaat
     4681 catatttcgt tatactagat aaaaaaggaa aggactgcta tgccgaattt attaacttat
     4741 cttgaagaaa ctcaatacga taatttttat gataaaccta tcaataagct agatattctg
     4801 gctctgaccg aactttccta cctccctttt gataatctgg tcccctactc ttttacagaa
     4861 aatggtgtac gacttgatcg gttggcagcg gcctttgaag agacctacaa aaataatttc
     4921 cctccctttt ctatggtgac caaaaaccgc ctagccttac taggacttct attcaaatcc
     4981 aaacgcttca aatctatcaa ggcatttggc ttcgttgacg attatcagtt ggaacaggaa
     5041 aagcagtttt cagcaatcag ctatcgcatt gaccgaaaaa cgattgtgac ttgcttcaga
     5101 gggacagatg atactattat tggttggaag gaagatttcc acatgaccta tatggatgaa
     5161 attcctgccc aacgtgcagc gagtggctac ttagaaaaac ttatgatgca gcaggggggc
     5221 catttttatc tggccggtca ttcgaaaggt ggaaatttag ccctctatgc agcatgccag
     5281 caagctacag accaacagga tagaattcta gctatctatc cctttgattc acctggctta
     5341 cacaaaaaac acttggaagc acctagttac caagctattc accaacggat tttccctgtc
     5401 attccccaga attcaatcgt cggtatgatg ttagaaacac cagaaaatgc tcagattgtc
     5461 cagagtaata ccctcggcat tctacaacac atcagttttt cttgggaggt tgacggaagc
     5521 gacttcaaaa tagcccctgc cctgaccagc gatagcctac aaacagacca agccttaaaa
     5581 acttggacgg atagtttaac agacgatgaa ttacgagact tcttcgattt gtttttcggc
     5641 atcttcatca aagcaggaat tgaacgattt agcgacatca cggtaaatcc cctacagaaa
     5701 ttacaggaaa ttgatcgact gagaaaagaa atagctccag aagaagccga aatggtagac
     5761 aaactcattc ggctcctctt tgacacccgc taccaaattt ggagggacaa tattagcact
     5821 tccattccaa gccctgaaat ctctctacca gattggcgga aacttttcca aagaaataca
     5881 actgaaaata aagaaaacta gctcaaccac ttgagctagt tttctttatc aaatcttctt
     5941 aaaaattgag ataatttttc taatcctttg attagagttt cttgttcaca ggcaaaacct
     6001 agacggacat agccgtcacg atcaaaacga ttgccaggaa ctagaagaac accgtattcc
     6061 tgcagaagtt gcaagcaaaa atcttccata ggcatatcca ctgcaatctt gacaaagcta
     6121 gtggaaacaa ccgctggacg gatataggaa acgaggggtt cttcctcaat ccattggtcc
     6181 aaaattgcta aattttcttc taaaatgcgc agatttcgtt ctagaatttc ttgataatgg
     6241 gccaaagcta attgagccac cagatcgtca aagacacctg cacaaatcat agtgtaatcc
     6301 cgataatctc tcagaatgtc cgtcacttga tgattggcgg ccacccaacc cacgcgaata
     6361 cctggcagag aataggtctt ggataagcta tttacagcaa ttcctttatc atagacttct
     6421 ataatagatg gcacatccag ctcagaaaag gaacgataga cttcatctga taggatgtaa
     6481 gccccaactt cactagcaat ttccgccaat tcttccaaat aagccctatc catgacagcg
     6541 ccggttggat tattggcatt gttgatgcaa atcatcttag tgttaggacg aatgagctga
     6601 cgcagttttt ccaagtctgg caaccatcca tgctcttcct caatctgcca caaatccact
     6661 tctgctccca aagactttgg aatatcgtag agttgttggt aggtcggata aagggaaatg
     6721 acatggtctc ctggctcaat caaaccataa agaactaaca agtttgcccc tgttgccccg
     6781 ttggtctgga gaatttgttc tggcttgacg cctgtataga gttgactaac cgatttttta
     6841 aatgctggcg aaccttctat ccagccatag ttgagcttgg tgccctgtaa tttcttataa
     6901 aaatcctcag gattggtgcc cgacaaggca aatagttcct ccaaagtcaa tgaagaaata
     6961 gacactcctg caatatcata aatcgcgctg ttttcatgga cattcagcca ttcctcaacg
     7021 ccaaaacgtg gtaatttcat aagacttcct acttttattt attctaccct tatt
//
LOCUS       DBNFCO010000081         6869 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.081, whole genome shotgun sequence.
ACCESSION   DBNFCO010000081 DBNFCO010000000
VERSION     DBNFCO010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6869)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6869)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6869
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.081"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(<1..832)
                     /locus_tag="AC1PIV_001656"
     CDS             complement(join(<1..529,529..832))
                     /locus_tag="AC1PIV_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HIP6612663.1"
                     /translation="MAYSLDFRKKVLAYCEKTGSITEASAIFQVSRNTIYQWLKLKEK
                     TGELHHQVKGTKPRKVDRDKLKNYLETHPDAYLTEIASEFDCHPTAIHYPLKAMGYTP
                     KKKSCTYYEQDPEKVELFLKELNNLSHLTPVYIDETGFETYFHRKYGRSLKGQLIKGK
                     VSGRRYQRISLVAGLINGALIAPMTYKDTMTSGFFEAWFKTFLLPTLGKPSVIIMDNA
                     KFHRMSKLKDLCEEQGHRLLPLPPYSPEYNPIEKIWAHIKKHLRRVLPNCDTFLEALS
                     S"
     gene            1126..1575
                     /locus_tag="AC1PIV_001657"
     CDS             1126..1575
                     /locus_tag="AC1PIV_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009909619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HIP6612664.1"
                     /translation="MRTVEQSLNENKHALHSLVVFRRAANTIAKSELETIKKYGLTVC
                     QFGVMEALYNKGNLRIQDLIDKLLSTSGNMTVVIKNMIRDGYIYKTIDTNDRRASLIA
                     LTPLGRETIEKILPEHYDHVGEIFSVLSSEEQDQLAEILKKFKNQQT"
     gene            1638..2183
                     /locus_tag="AC1PIV_001658"
     CDS             1638..2183
                     /locus_tag="AC1PIV_001658"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase [NAD(P)H] activity
                     [Evidence IEA];
                     GO_function: GO:0008753 - NADPH dehydrogenase (quinone)
                     activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050136 - NADH:ubiquinone reductase
                     (non-electrogenic) activity [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HIP6612665.1"
                     /translation="MANVLFLVGSLRDGSFNHQMAKKAEAFLTDKAQVSYIDLAKIPL
                     FNQDIETPILPEIAELRAQVDAADAIWIFSPVYNYAIPGIVKNALDWLSRSLDLSNPK
                     GPSILQDKITTVSAVANSGHDHLFKDFQHLLPFIRTQIAGEFTGSTINPEAWGTGVLE
                     LSDETLTKLEQQVADLLAAIQ"
     gene            complement(2283..3395)
                     /gene="glf"
                     /locus_tag="AC1PIV_001659"
     CDS             complement(2283..3395)
                     /gene="glf"
                     /locus_tag="AC1PIV_001659"
                     /EC_number="5.4.99.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002941733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008767 - UDP-galactopyranose mutase
                     activity [Evidence IEA];
                     GO_process: GO:0009273 - peptidoglycan-based cell wall
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
                     /protein_id="HIP6612666.1"
                     /translation="MKKYDYLVVGAGLFGAVFAHEAAKKGKKIKVIEKRDHIAGNIYT
                     KEVEGIQVHEYGAHIFHTSEKEIWDYVNQFAEFNSYTNTPVANYKGEIYNLPFNMNTF
                     NKLWGVVTPAEAGAKIAEQRAVLGGKTPENLEEQAISLVGTDIYEKLIKSYTEKQWEK
                     PCTELPAFIIRRLPVRLTYDNNYFNDTYQGIPIGGYTQIVEKMLEHENIDVETNVDFF
                     ANKEDYLATYPKIVFTGMIDEFFDYQLGELEYRSLRFETEVLDMENYQGNAVVNYTDS
                     ETPYTRIIEHKHFEFGTQPKTIITREYSKTWKRGDEPYYPVNNNRNNHLYTAYKKLSE
                     QQENVIFGGRLGHYRYYDMHQVIGAALQCVRNEVGE"
     gene            3621..3874
                     /locus_tag="AC1PIV_001660"
                     /pseudo
     CDS             3621..3874
                     /locus_tag="AC1PIV_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558050.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(3809..5740)
                     /locus_tag="AC1PIV_001661"
     CDS             complement(3809..5740)
                     /locus_tag="AC1PIV_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000740018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HIP6612667.1"
                     /translation="MKTNNVEIIKADSLVRRRGVKVERHLKRVAAYCRVSSDSEDQKN
                     SYESQVRHYKDYISQRSDWELAGIYADEGISGTQVGKRQDFQRLINDCVNGEIDYIVT
                     KAIARFARNTLDTLKYVRMLKDMQIGVYFEEENIDTLTMDGELLLTILSSVAQQEVEN
                     TSAHVKKGLKMKMQRGELIGFQGCLGYDYDVETKQLSINKKEAKIVRYIFERYLEGIG
                     GKVIARELDELGYKSPRGLDHWNDTTVLGIIKNEKYKGDILMGKTFTVDPISKRRLSN
                     FGEEDKYYIKDNHEPIISKEDFEKAQEIRLRRAGNKKTVANVNGKRERYSKMYAFSSM
                     LECGFCGSILSRRSWHCRSDYRKVVWHCVTSIKKGKKFCKHSKGLEELAIEGAFMEAY
                     RQLYHSNENLMTDLLETIESELNDNSLNKELKRITNKLRTLLKKEENLVNLRLEGKIS
                     DTIYNEKYNEISSEKEFLAEEKVNIETTLKSEIDVKKRLTEFKHLLSSQKMLTEFDRA
                     VFESIVEKIIVGGVNSDGEIDPAMLTIIFKTGETQNKDGKQFKSKRKNAKLETDKLCP
                     QNSDEDKKLYSQGTDYTHRSCGIIRKTQLDCPVCSPVFWQAASKDPRTFELSNTHHVD
                     SCHTYTKIKCQQALSRVIA"
     gene            complement(6245..6649)
                     /locus_tag="AC1PIV_001662"
     CDS             complement(6245..6649)
                     /locus_tag="AC1PIV_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HIP6612668.1"
                     /translation="MKYYIHVRGSKIPVTETVYKSYWQLVNHEKYLNRKDRKFGVLPF
                     SSFEVDGLLLANVLPDTTVDVERFIENKLLIEQLNEALLTLSDKEFKIIDALYFREHT
                     IREVAIEHEMSATSLFRMRNTILDNLRKFFEK"
BASE COUNT         1993 a         1421 c         1088 g         2367 t
ORIGIN      
        1 caggacgaaa gtgcctcaag aaaagtatcg caatttggca atactcttct gaggtgtttt
       61 ttgatgtgag cccatatttt ctcaatggga ttatattccg gtgagtaagg aggaagtggt
      121 aaaagtctat gtccctgctc ctcgcataaa tcttttagct tactcatcct atgaaacttt
      181 gcattgtcca taatgataac agatggttta cctaaagtgg gtagtaagaa tgttttgaac
      241 caagcttcga aaaagccact cgtcatagta tctttgtatg tcatcggggc tataagcgca
      301 ccatttatga gacctgctac taaagatatc cgctggtatc ttcttccaga gaccttacct
      361 tttatcaact gacctttcaa agagcgacca tattttcgat gaaaatatgt ctcaaaccct
      421 gtctcgtcaa tataaacagg agtcaagtgg cttaagttat tcaattcttt aaggaacagt
      481 tctacttttt cagggtcttg ttcatagtag gtacagctct tttttttcga gtatatccca
      541 tagctttgag ggggtaatga atagctgttg gatgacagtc aaattcagaa gctatttcag
      601 tcaaataagc atctggatga gtttcaagat aattctttaa tttatctcta tccacttttc
      661 ttggcttggt tcctttaact tggtgatgaa gctcgccggt tttctctttt aattttagcc
      721 attgatagat agtgttacgt gaaacttgga aaatagctga tgcttcagta atactgccgg
      781 ttttctcaca gtatgcgaga acttttttac gaaaatctaa tgaatatgcc ataaatacat
      841 tatatcataa atgtactgtt tttgtttcat ttaactataa ataaaatttc cttttccttc
      901 acacaaagaa aaggatataa aaacctacat tcacagtttt gcacttccat ctaagactat
      961 ttctcaaatg ctcattgctc gttttttcca gtacagttag tattacctca aaaaacgaac
     1021 ttgattaact aaaaactatc ttttccataa aagtacttta cctatgaata taggatttaa
     1081 ctttttttgc ttgataaccg aacgatttat tgctaaaata ttctcatgag aactgttgaa
     1141 caatctttaa acgagaacaa gcatgcactt cacagtctag tcgtctttcg cagagcagct
     1201 aatactatcg caaaatcaga attagaaaca atcaaaaaat acggactgac agtttgtcag
     1261 tttggagtga tggaggcact ctacaacaaa ggaaatctgc ggattcaaga cttaattgat
     1321 aaattattaa gcacttctgg caacatgact gtcgttataa agaacatgat tcgagatggt
     1381 tatatctaca agactatcga tacaaatgac cgtcgtgctt ccttgattgc tctcactcca
     1441 cttggacgcg aaaccattga aaaaatcctt ccagagcatt atgatcacgt tggagagatt
     1501 ttttctgtcc ttagttcaga agaacaagac caattagccg agatacttaa aaaattcaag
     1561 aatcagcaga cctaggattg tcaacaaaag acaaatacga tatactaaat ttatgttttt
     1621 atgaaaagga ggccatcatg gcaaacgtat tgtttttagt tggttcacta cgtgacggtt
     1681 cttttaacca tcaaatggca aaaaaagctg aagcattctt gactgataag gctcaagtat
     1741 cttacattga tcttgcaaaa attcccctat tcaaccaaga catcgagaca cctatccttc
     1801 ctgaaattgc agagctacgt gcacaagtag acgctgcgga tgctatctgg attttctcac
     1861 cagtatataa ctatgcaatc ccaggcatcg taaaaaatgc tctcgattgg ctcagtcgtt
     1921 cgctcgattt atccaatcca aaaggaccat ctatcctaca agataaaatc acaactgtct
     1981 ctgcagtcgc aaacagtggt cacgaccacc tattcaaaga cttccaacac cttcttccat
     2041 ttattcgcac tcagattgct ggtgaattta caggttcaac catcaatcca gaagcatggg
     2101 gaacaggtgt attggagtta tctgacgaaa ctctaacaaa actcgaacaa caagtagctg
     2161 acctgttggc agcaattcaa taataatcaa aaaaaaccag aatttctggt ttttttgatt
     2221 aacattttaa gagcattccg acttctgcca agaataatta ctactttgat gacttctcaa
     2281 aatcattccc caacttcatt tctcacacac tgtaaggcag ctccgatgac ttggtgcata
     2341 tcgtagtaac gataatgacc aagacgccca ccgaatatga cattctcttg ttgttctgac
     2401 aatttcttat atgctgtgta tagatggtta ttgcgattat tgttgactgg atagtatggc
     2461 tcatcgcctc gtttccaggt cttcgaatac tcacgtgtaa taatggtttt cggttgtgta
     2521 ccaaattcga agtgtttgtg ttcgatgatt cgagtatatg gtgtctcgct atctgtatag
     2581 ttgacaaccg cattcccttg atagttttcc atatccaaca cttctgtctc aaatcgaagg
     2641 ctacggtact ccaattcacc aagttggtaa tcaaagaact cgtcaatcat tcctgtaaag
     2701 acaatctttg gataggtagc taaatagtct tccttattgg caaagaaatc aacatttgtc
     2761 tccacatcga tattttcatg ttccaacatt ttttctacaa tctgcgtgta accgccgatt
     2821 ggaatacctt gataagtatc gttaaagtag ttattatcat aagtcaaacg cacgggcaaa
     2881 cgacggatga tgaaggctgg taactccgta catggttttt cccattgttt ttctgtgtag
     2941 gacttgatca atttttcata gatgtctgta ccaacaagtg agatggcttg ctcttccaag
     3001 ttttcaggcg ttttaccacc caacacagct cgttgctctg caatcttcgc tcctgcttca
     3061 gcaggtgtca ccacgcccca cagtttattg aaagtattca tgttgaaggg aagattgtaa
     3121 atctcacctt tgtagttggc gactggtgtg tttgtatagc tgttgaactc cgcaaactga
     3181 ttcacataat cccaaatttc tttttcagaa gtatggaaaa tatgtgcgcc atattcatgg
     3241 acttgaatac cttctacttc ttttgtatag atgttacccg caatgtggtc tcgtttttcg
     3301 ataaccttta tttttttacc ctttttagct gcctcatgag caaagaccgc tccgaacaga
     3361 cccgctccga caactagata atcgtatttt ttcatattgt ttttacattt aactttctaa
     3421 ggaagtcatt tctccaaatc ttttactaga ctatcattaa taccatcgtc tcataactaa
     3481 taaagaatga gttgtgataa tctcttccct aaaacctttc acttaaagct tgcaatatcc
     3541 aatattataa cagacaatac aaccttcatc aagtttagca atagacttgt tcggtaactc
     3601 aaaggcggta tactaaaggt atggaaacaa catacgaaaa agtcttaaaa ttaaactcag
     3661 agaatttcaa attgttgata ggtgtaaaaa agcgacgttt catctgatgc ttgattgtct
     3721 cactgacgct tatcaagagc aacaccgaaa aggaggacgc ccacgccgtc taagtatgga
     3781 agagcagctt atcatgacct tgcgctactt acgctattac ccgactcaac gcttgttggc
     3841 atttgatttt ggtgtaggtg tggcaactgt caacatgatg cgtatttgag agttcaaagg
     3901 tcctggggtc ctttgaagct gcttgccaaa aaacaggaga gcatactgga caatctaatt
     3961 gcgtttttct aataatccca caacttctat gtgtgtagtc tgttccttga gaatacaatt
     4021 ttttatcctc gtcactgttt tgaggacaca atttatctgt ttctagttta gcatttttac
     4081 gtttactttt aaattgttta ccatccttgt tttgagtttc acctgttttg aatattatgg
     4141 ttaacattgc aggatcaatt tctccgtcgc tattaactcc acctacaata attttctcaa
     4201 caatactttc aaaaactgca cgatcaaact ccgtaagcat tttctgtgaa gatagtaagt
     4261 gcttaaactc agttagtctt ttctttacat cgatttctga ttttaaggtt gtttcaatat
     4321 ttaccttctc ttctgctaga aactcttttt ctgaggaaat ttcattgtac ttttcattgt
     4381 atatggtatc gctaattttc ccttcgagcc ttagatttac aagattttcc tctttcttta
     4441 gtaatgttcg aagtttgttt gtaatccttt ttaattcctt gttaaggcta ttgtcattca
     4501 attcagattc aatcgtttca agtaagtctg tcattaagtt ttcatttgaa tgataaagtt
     4561 gtctgtaagc ttccatgaaa gccccctcaa tagcgagctc ttctaatcct ttactatgct
     4621 tacaaaattt ctttcctttc tttatcgatg taacacagtg ccacacaacc ttgcgataat
     4681 ctgaacggca gtgccaactt cttctagata atattgaacc gcaaaaacca cattctaaca
     4741 tgctactaaa agcatacatt tttgaatagc gttcacgttt tccatttaca ttcgcaactg
     4801 tctttttatt tcctgcccta cgcaacctaa tctcctgagc tttctcaaag tcttctttag
     4861 atattatagg ttcatgatta tctttgatgt agtacttatc ttcttcacca aaattactta
     4921 aacgtctctt gcttattgga tccactgtaa aagttttgcc cattaaaata tcgcctttat
     4981 atttttcatt ctttatgatt cctaagactg ttgtatcatt ccaatgatct aatcctctcg
     5041 gcgatttgta acctagttca tcaagttccc ttgcaattac ttttcctcca ataccttcta
     5101 agtacctttc aaagatatag cgaactattt tggcttcttt tttattgatt gaaagttgct
     5161 tggtttctac atcatagtca taccccaagc atccttgaaa ccctatcaat tcaccacgtt
     5221 gcatcttcat ttttaatccc tttttcacat gtgcagatgt attttctact tcttgctgtg
     5281 caacggagct tagaatagtc aaaagcaatt ctccatccat tgttagggta tctatgtttt
     5341 cttcctcaaa atatactcca atttgcatat cttttaacat tctgacatat ttcaaagtat
     5401 ctagggtatt cctggcaaat ctagcaattg cctttgtgac aatgtaatct atttctccat
     5461 ttacacaatc atttattaat cgttgaaaat cttgtcgctt tcctacttgt gttcctgaaa
     5521 tcccctcatc tgcatagata cctgccagtt cccaatccga ccgctgagag atataatctt
     5581 tataatgtct cacctgagat tcatagctgt tcttctgatc ttcgctatca gaacttactc
     5641 ggcaataggc agcaactctt tttaaatgtc tttctacctt gacacctcta cgtcgaacta
     5701 aagaatcagc ttttattatt tcaacattat ttgttttcat actgaaaccc ctccttttga
     5761 ttctatatta ccgcgttcta ataaaaaggt cagctatttt gtgtactcaa tacgcagtct
     5821 gtttctgatt ttttcatatt catttttaga taacaattct ttagagtata aaaaattaag
     5881 cattgataac tgcagactat attttacaac tgtttgttcc aaaatttttc ctcctgataa
     5941 cgtgatactc aattatttcc tccgtgggta tgattggtta aatcactcat gggcatctca
     6001 cccgctgtcc tttctcgatg gcagcctgaa cgttcagaag tatcattatc ctcatttgtc
     6061 tcatggcaga taggtaacca acctatttta tagccgataa ttctcgctca tctcacagcg
     6121 taccaggcta aattgctcca caaatgatta aagtcccact tcagtctatt cagttgtcaa
     6181 agggcaaaaa gagactaaaa attcctctca ctataaagag tgaatttttt agtctcctgt
     6241 ttccttattt ttcaaaaaat tttcgtaggt tgtccaaaat tgtatttctc atccgaaata
     6301 gactagtcgc agacatctca tgctctattg ctacttctct gatggtatgc tctctaaaat
     6361 acagagcatc aatgatttta aactctttat cagataaggt taataaagcc tcatttagtt
     6421 gctcaataag gagcttgttt tctataaaac gttcaacatc aacagttgta tcaggcagta
     6481 catttgctag cagtaaccca tctacttcaa atgatgaaaa aggtaatact ccaaatttcc
     6541 tatcttttct attcagatac ttctcgtgat tgaccaattg ccagtagctt ttataaaccg
     6601 tttctgttac ggggatttta ctacctctaa cgtgaatata atatttcatt tcagcctccg
     6661 tttatgattt tttcttagtc ataaaaggag ggctccttat ctcaaccata gctatttctc
     6721 acttttatca aatcaaggag ttctcctcac tataagagtg aaaatatggt gctcttgttc
     6781 caaaaaaaat tatatgtacc aaaaaacagc aagctcttct gaacttgctg atctatattt
     6841 taataagttt ctgtttagta ggtaacaat
//
LOCUS       DBNFCO010000082         6844 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.082, whole genome shotgun sequence.
ACCESSION   DBNFCO010000082 DBNFCO010000000
VERSION     DBNFCO010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6844)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6844)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6844
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.082"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            36..860
                     /locus_tag="AC1PIV_001663"
     CDS             36..860
                     /locus_tag="AC1PIV_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HIP6612669.1"
                     /translation="MTWVTNQSVVLQALLGGLFTWFCTIVGSAVVFFFKTVSRRLLDT
                     MLGFAAGVMIAASFWSLLAPSIEYAESSYGNLAWIPAAVGFAAGGIFLRLVDAWVPHL
                     HLGNDKDKAEGGGEKDRKNLSKTALLFLAITIHNIPEGLAVGVIFGALASNYSPAAFI
                     GAIGLAIGIGIQNIPEGAALAIPIRTDGASRWKAFYWGSMSAIVEPIAAVIGAFAVTF
                     MTPILPYALSFAAGAMIFVVVEELIPESQTNGNTDIATLGLMAGFIIMMILDVALG"
     gene            958..1827
                     /gene="rfbA"
                     /locus_tag="AC1PIV_001664"
     CDS             958..1827
                     /gene="rfbA"
                     /locus_tag="AC1PIV_001664"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HIP6612670.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPIYDKPMIYYPLSTLMLA
                     GIKDILIISTPQDLPRFKDMLGDGSELGISLSYAEQPSPDGLAQAFIIGEEFIGDDNV
                     ALILGDNIYHGNGLTKMLQRAASKEKGATVFGYQVKDPERFGVVEFDADMNAISIEEK
                     PEEPKSNFAVTGLYFYDNDVVEIAKNIKPSPRGELEITDVNKAYLERGDLSVELMGRG
                     FAWLDTGTHESLLEAAQYIETVQRLQNVQVANLEEIAYRMGYITKEQVYKLAQPLKKN
                     EYGQYLLRLIGEA"
     gene            1827..2420
                     /locus_tag="AC1PIV_001665"
     CDS             1827..2420
                     /locus_tag="AC1PIV_001665"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018029578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HIP6612671.1"
                     /translation="MTENFFGKTLAARPVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGTWVDLREG
                     ETFGNTYQTVIDASKSIFVPRGVANGFQVLSDFVAYSYLVNDYWALELKPKYAFVNYA
                     DPSLDIKWENLEEAEVSEADENHPFLKDVKPLRKEDL"
     gene            2420..2905
                     /locus_tag="AC1PIV_001666"
     CDS             2420..2905
                     /locus_tag="AC1PIV_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HIP6612672.1"
                     /translation="MFQAFLEIAEQLNKLGITPLLMGSVGLERRTGRDWQARDLDIHV
                     PSDPRGWEAPDEERIYRADELIVLMNQLGYVLVDRHEHEFHKDGLSVEFGGLHSLPEF
                     AGVELEDLEELETVGVRYYLPTLEQYLKIYQASSKDSYRAENNNQKDFAKIAYLKEIL
                     R"
     gene            3094..4140
                     /gene="rfbB"
                     /locus_tag="AC1PIV_001667"
     CDS             3094..4140
                     /gene="rfbB"
                     /locus_tag="AC1PIV_001667"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HIP6612673.1"
                     /translation="MSQFKNIIVTGGAGFIGSNFVHYVYNNHPDVHVTVLDKLTYAGN
                     KANLEAILGDRVELVVGDIADAELVDKLAAKADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETNYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILAGIKPKLY
                     GEGKNVRDWIHTNDHSTGVWAILTKGRMGETYLIGADGEKNNKEVLELILEKMGQPKD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWTPQFTDFSQGLEETIQWYTDNQDWWKAEKE
                     AVEANYAKTQEVIK"
     gene            4195..5046
                     /gene="rfbD"
                     /locus_tag="AC1PIV_001668"
     CDS             4195..5046
                     /gene="rfbD"
                     /locus_tag="AC1PIV_001668"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019780653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008831 - dTDP-4-dehydrorhamnose reductase
                     activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HIP6612674.1"
                     /translation="MILITGANGQLGTELRYLLDERGVDYVAADVAEMDITDADKVDA
                     FFAEVKPSVVYHCAAYTAVDMAEDEGKELNYKINVTGSENVAKATAKYCATLVYISTD
                     YVFNGDLPVGKEWQVDDQPDPQSEYGRTKRKGEEAVEKFADKFYTVRTAWVFGNYGKN
                     FVFTMQNLAETRDTLTVVNDQHGRPTWTRTLAEFMVHLVDTKQAFGYYHLSNDAAEDT
                     TWFDFATEVLKDTNTKVLPVDSSQFPAKAKRPFNSTMSLDKAKATGFVIPTWQEALEA
                     FYKQEKK"
     gene            5063..6106
                     /locus_tag="AC1PIV_001669"
     CDS             5063..6106
                     /locus_tag="AC1PIV_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HIP6612675.1"
                     /translation="MKKKAIVKPLLMSGIFLALLGGATLPSGAVPVVAAETSQSTTYH
                     LTDDEKVAVREYIQAKMTIDMQEYRLAFLEGMMEEMASGSAEAAWDEEIADLKANLTA
                     EQVVVLDELEANLIGSIAQHYHYLFETLTVAGKSGREEAAAIVSKYESEDDASTPEAE
                     LAALKYAREVIVELLNKESAAIDNYIAYAEATGQELAGLLESGNSNLESITSATIGYG
                     QALATASQPKFPYDFSEMDRQIAELTASLQSKVEDKSTAKTENTGVQTSQSATNGSND
                     LQTVPDQGGGQISDVATGKGNISEAGQKKVIPNDNAKVLPKTSGKSSLPLTVLGLITI
                     FAGWLLTNKQEEK"
     gene            6174..>6844
                     /locus_tag="AC1PIV_001670"
     CDS             6174..>6844
                     /locus_tag="AC1PIV_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GBS Bsp-like repeat-containing protein"
                     /protein_id="HIP6612676.1"
                     /translation="MFVKKRTLLFLSLCASALNAQLVQADMVNAPSSQVSSSQVAETG
                     GQLSVVDEAGQIKAILSNIQGEIIGVTAQFSSETNSGITVTFSMDEQGRYVAVLDRSA
                     FAEEDQVFSLKLTAQLTDGSFQTLSDYSFEWKKDVVSAAEKPTALDNSDATPSKIEEE
                     ATSTTTSSTVNSSLTAGATSSTSNSLTRSSSNTIAGSSNGSTSVPSARVSTASSSVNV
                     TQPTGT"
BASE COUNT         2034 a         1316 c         1598 g         1896 t
ORIGIN      
        1 ggatatgcaa gattaaacag gataggatgt tagttatgac ttgggttact aatcagtctg
       61 tagttctaca ggctttgcta ggtggtttat tcacatggtt ttgtacgatt gtggggtctg
      121 ccgttgtatt tttctttaag acagttagtc gtcgtttgct agacaccatg ttaggctttg
      181 cagctggtgt tatgattgcg gcttcttttt ggtctttatt agccccatcg attgagtatg
      241 ctgaaagttc atacggcaat ctggcttgga taccagcagc agtaggtttt gcagcaggtg
      301 gtattttttt acgcttggta gatgcctggg ttccgcattt gcatttggga aatgataaag
      361 ataaggcaga aggtggtggt gagaaggata gaaaaaatct atccaaaaca gccctgctct
      421 tcttagctat tacaattcac aatattcctg aaggtttggc ggtcggtgtg atatttggtg
      481 cacttgcttc taactatagt ccagcagctt ttatcggagc aattggtctt gctattggga
      541 ttggtataca aaatattcct gaaggggcag ccttggctat tccaattcgt acagacggcg
      601 catctaggtg gaaagctttt tactggggat caatgtcagc aattgtcgag ccgattgcag
      661 cagtcatcgg tgcttttgcg gtcactttta tgacacctat tttaccttat gccctctcct
      721 ttgcggcagg ggccatgatt tttgtcgtcg tagaagagct cattccagaa tcgcagacaa
      781 acggcaatac ggatattgca actctgggct taatggctgg ttttatcatc atgatgattt
      841 tagatgttgc tctaggataa tttgttaaag tctgtcgtca caggcttttt tcttatgaca
      901 atatctttaa aaatatggta taatgaactg atattaattt agggaaggta ctcttatatg
      961 aaaggtatta ttctagcagg tggttcaggt acgcgccttt atcctctgac acgtgcggct
     1021 tcaaaacaat tgatgcctat ctatgacaaa ccaatgattt attatccatt gtcaacattg
     1081 atgttggctg gaatcaaaga tattttgatt atttcaactc cgcaagatct tccacgtttt
     1141 aaggatatgt taggagatgg ttctgaactt ggaatttcac tttcatatgc agaacaacca
     1201 agtccagatg gtttggcgca agcctttatt atcggtgaag aatttatcgg tgatgacaat
     1261 gtagccttga ttcttggtga taacatctac cacggaaatg gtttgaccaa gatgttgcaa
     1321 cgtgctgcta gcaaagaaaa gggagcgact gtctttggtt atcaagtaaa agatccagaa
     1381 cggtttggtg ttgttgagtt tgacgctgat atgaatgcca tctctatcga agaaaaacct
     1441 gaagagccaa aatcgaattt tgctgttact ggtctttatt tctatgacaa tgatgttgtg
     1501 gagattgcga aaaatatcaa gccttcacct cgtggcgagt tggaaatcac agatgtcaac
     1561 aaggcttact tagaacgcgg cgacttgtct gttgagctta tgggccgtgg atttgcttgg
     1621 ttggatacag gtacgcatga aagcctcttg gaagctgcac agtacatcga aacggttcaa
     1681 cgtttgcaaa acgttcaagt ggctaatttg gaagaaattg cttaccgcat gggctacatt
     1741 acaaaagaac aagtgtataa attggcacaa ccgcttaaga aaaatgaata cggacaatac
     1801 ttgctccgtt tgattggaga agcttaatga cagaaaactt tttcggtaaa acactagcag
     1861 ctcgcccagt tgaagctatt ccaggaatgt tagaatttga cattcctgtt catggcgaca
     1921 accgtggctg gtttaaggag aacttccaaa aggaaaaaat gttgcctctc ggctttcctg
     1981 aaagcttctt tgcagaagga aaattgcaga ataatgtttc cttctctcgt aaaaacgttc
     2041 ttcgtggtct tcacgcagag ccttgggata aatacatttc agtagcagac ggcggtaagg
     2101 ttttgggaac ttgggtcgat ctacgtgaag gcgaaacctt cggtaatacc taccaaaccg
     2161 ttatcgatgc ttcaaaaagt atcttcgttc cgcgcggagt agccaatggt ttccaagtct
     2221 tgtcagattt cgtggcttac agctacttgg ttaacgacta ctgggctttg gaactcaagc
     2281 ctaagtatgc tttcgtcaac tacgctgacc ctagcctcga catcaagtgg gaaaacctag
     2341 aagaagcaga agtttcagaa gcagatgaaa accacccatt cctcaaggac gtcaagcctt
     2401 tgagaaaaga ggacctctaa tgtttcaagc ctttttggaa atagcagagc agttaaacaa
     2461 gttaggaatc actcccttgt taatgggttc tgttggtctg gaaaggcgga caggacgaga
     2521 ttggcaggca agggatcttg atattcatgt gcccagtgac ccacggggat gggaagcgcc
     2581 agatgaggag cggatttacc gtgcagatga gctgattgtt ctgatgaatc aacttggcta
     2641 tgtcctggtt gatcgtcatg aacatgaatt tcataaagac ggcttatctg ttgaattcgg
     2701 aggcctacat tcactgcctg aatttgctgg tgtagagcta gaagatttgg aagaactaga
     2761 aacagtaggt gttcgctatt acctaccgac acttgaacaa tacctgaaaa tctaccaagc
     2821 ctcttcaaaa gattcctacc gtgcagaaaa taacaatcaa aaagactttg ctaagattgc
     2881 ttacttgaag gaaatcttga ggtaaaaaag cgagcgaagc gagcagttct gtgtgtcatc
     2941 gccgtagtga gaagctcctt tgctttgcta aggagcgggg gaaaccatga gaccttaggc
     3001 tcatggttta gtaatgaaac accttggcgg ttgcttacga ccccactacc taagatgaca
     3061 cacaaaaaag aaaaaaactt ttcggagaaa aaaatgtctc aatttaaaaa tattatcgtg
     3121 actggtggag ctggtttcat cggttcaaac tttgtacact atgtatataa caatcatcca
     3181 gacgttcacg taactgtttt ggataaactt acttatgcag gaaacaaggc taacttggaa
     3241 gctattcttg gtgaccgtgt tgagctggtt gttggcgaca ttgcagatgc tgagttggtt
     3301 gacaaattgg ctgctaaggc agatgccatc gttcactatg cggcagaaag ccacaacgac
     3361 aactctctca acgatccaag cccatttatc cataccaact ttatcggtac ttacactttg
     3421 cttgaagcgg ctcgtaaata cgacatccgt ttccaccatg tatcgaccga cgaagtatac
     3481 ggtgaccttc ctttgcgtga agatttgcca ggtcatggcg aaggtccagg cgagaaattt
     3541 actgcggaaa ccaactataa cccgtcatca ccttactcat caaccaaagc tgcttcagac
     3601 ttgattgtca aagcatgggt gcgttcattt ggtgtcaaag caactatctc aaactgttca
     3661 aacaactacg gtccttacca acacatcgag aaatttatcc cacgccaaat caccaatatc
     3721 ttggcaggta ttaagccaaa actttacggt gaaggtaaaa acgtccgtga ctggattcat
     3781 accaacgacc actcgacagg tgtttgggca attttgacaa aaggccgtat gggtgaaact
     3841 tacctaatcg gtgctgacgg tgagaagaac aacaaagaag tgcttgaatt gattcttgaa
     3901 aaaatgggtc aaccaaaaga tgcttacgac cacgtgactg accgtgcagg acacgatttg
     3961 cgctatgcta ttgacgcaag caaacttcgt gacgagcttg gttggacacc acaattcaca
     4021 gacttctctc aaggtttgga agagactatc cagtggtata cagataacca agactggtgg
     4081 aaagctgaaa aagaagctgt tgaagccaac tatgctaaga cacaggaagt tattaaataa
     4141 gattattaaa ggctagggct cttgcccaag cctttcttga aataaggagc aaatatgatt
     4201 ttaattacag gtgcaaatgg tcagttgggt acagaattgc gttatctctt ggatgagcgt
     4261 ggtgttgatt acgttgccgc tgacgtagca gaaatggaca tcacggatgc agataaagta
     4321 gatgccttct ttgcagaagt aaagccaagc gttgtatacc actgtgcagc ctacacagct
     4381 gttgatatgg cagaggatga aggcaaggaa ctcaactaca agattaacgt aacaggctct
     4441 gaaaatgttg ccaaggcaac cgctaaatac tgtgcgaccc tcgtttacat ctcaacggac
     4501 tatgtcttca atggtgattt gccagtcggc aaagagtggc aagtagatga ccaaccggat
     4561 cctcaatctg aatacggtcg caccaagcgc aagggtgagg aagcagttga gaaatttgct
     4621 gacaaattct acactgttcg tacagcttgg gtctttggta actacggtaa aaactttgtt
     4681 ttcactatgc aaaatcttgc ggaaacccgc gatactttga cggttgtcaa tgaccaacac
     4741 ggtcgtccaa cttggacccg tacccttgcg gaattcatgg tacacttggt ggacaccaag
     4801 caagcatttg gttactacca tttgtcaaac gatgcagcag aagatacgac ttggtttgac
     4861 tttgcgacgg aagtcctcaa ggataccaac accaaggtat tgccagtgga ttctagccag
     4921 ttcccagcca aggcaaaacg tccattcaac tcaaccatga gcttggacaa ggcaaaggcg
     4981 acaggttttg tcatcccaac ttggcaagaa gcattggaag cattctataa acaagaaaag
     5041 aaatagtcta caggagatgt gtatgaaaaa gaaagcgatt gttaagccgt tgttgatgtc
     5101 aggaattttt ctggctttac taggaggtgc tacattaccg tccggagctg ttccagttgt
     5161 agcagcagag acaagtcaaa gtacgaccta tcatttaact gatgatgaaa aagttgccgt
     5221 acgtgaatat attcaagcta aaatgactat cgatatgcaa gaatatagat tggcgtttct
     5281 tgagggaatg atggaagaaa tggcttcggg tagtgctgaa gctgcgtggg atgaagaaat
     5341 tgcagacttg aaggcaaact taacagcaga gcaagttgtt gttttagatg aactcgaagc
     5401 aaatttaatt ggtagcatag cccaacatta ccattactta tttgagacac ttacagtcgc
     5461 tggaaaaagc ggaagagaag aagcggcggc tatagtttct aagtacgagt ctgaagatga
     5521 tgcaagtact cctgaagccg aattggctgc attgaaatac gctagagaag ttatcgttga
     5581 actactgaat aaagagtcgg cagcgattga taattatatt gcttatgcag aagcaactgg
     5641 acaagaatta gctggattat tggaaagtgg aaactctaat ttagaatcta ttacatctgc
     5701 aactatagga tatggtcaag ctcttgcaac tgcttcgcaa ccaaaatttc cgtatgactt
     5761 ttcagaaatg gaccgacaga ttgcagaact aactgctagt ctacaatcaa aagtcgagga
     5821 taaaagtaca gctaagactg aaaataccgg ggtacaaaca agtcaaagcg ctacaaatgg
     5881 ctcaaatgat ttgcagaccg ttccagatca agggggcggt cagatttctg atgtagctac
     5941 aggcaaaggc aatatttccg aagcaggtca gaaaaaggtt atcccaaatg ataatgctaa
     6001 ggtattgcca aaaacttcag ggaaatctag tcttccatta actgtactag gactcataac
     6061 aatttttgct ggttggttat tgacaaataa gcaagaagaa aaatagaaga ttagtgtaat
     6121 tgcatctatt ttgagaaata tagttgtttt tacatgtgaa atacataaag gagatgtttg
     6181 tgaaaaaaag aacgttatta tttctttctt tgtgtgcatc cgcgttgaat gctcagcttg
     6241 ttcaagcgga tatggtaaat gccccatcta gtcaagtttc ttcatctcag gttgctgaaa
     6301 ctggcgggca gttatctgtc gttgatgagg ctggtcagat taaagctatt ctatcgaaca
     6361 ttcaagggga aattattggt gttacagccc agtttagctc tgaaacaaat agcggcatta
     6421 ctgtcacatt ctcaatggat gagcagggta gatacgtagc ggttttggat cggtctgcat
     6481 ttgcggagga agaccaagtc ttttcgctga agttaacagc acaattaaca gatggaagtt
     6541 ttcagacctt atcagattat agtttcgagt ggaagaagga tgtcgtaagc gcggctgaga
     6601 agcctactgc tttggataat agtgatgcaa ctccgtctaa aattgaggag gaagcaactt
     6661 cgactactac aagctcaacg gttaattcta gtttgacagc aggtgcaaca agtagtactt
     6721 cgaattcgct gacaagaagt tcttcaaata cgattgcagg aagttcgaat ggctctacaa
     6781 gtgttccaag tgctcgagtc agtacagctt ccagttcggt caatgttaca cagccaacag
     6841 gtac
//
LOCUS       DBNFCO010000083         6832 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.083, whole genome shotgun sequence.
ACCESSION   DBNFCO010000083 DBNFCO010000000
VERSION     DBNFCO010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6832)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6832)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6832
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.083"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            349..504
                     /locus_tag="AC1PIV_001671"
     CDS             349..504
                     /locus_tag="AC1PIV_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612677.1"
                     /translation="MNHPKFTLRKLSIGLVSLGAGVALSGTLYPQNTVTVYAETPVTE
                     STTLEKK"
     gene            573..3389
                     /locus_tag="AC1PIV_001672"
     CDS             573..3389
                     /locus_tag="AC1PIV_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serum opacification factor"
                     /protein_id="HIP6612678.1"
                     /translation="MKIRKERWLTPLLFSALPKSNAESASPEALTNENASEPTGQVAE
                     NTSSSEGKATEKEEPAVQYVEKEVDDYSTKVEKPNETVSSTVDKTPKELFTVSRTAEV
                     GQDGVVTVTTQIVPKEIDKGAEIVVLVDTSKKMDEEAKKAAKDNIVKLVKEMTDPTNN
                     HNSRNSVRVIGFNRKLSEAQEVNSITVEDTVEKLFTDAEQNYNWGVDMQGAIHEARRI
                     LESEKSGKRKHIVLLSQGESTFSYDLTDAAKTETKYKTINEDKVVHTNPLLPWPFTFD
                     VTVRRANLLKDAKSLIEFLNKLGITRFNEALDGVSTVAGLTDFIGKFFRNPLDYIDLA
                     DIDSSKLEEQKFNYEKQIGEGYHFRSFYERKLDPLPFKDAIVKKIKYNLKKELDKAAL
                     PTNTLSYIGKKIGLTNTSEKAIDLFANSLVDYIFYGRKNVFYNHNLSAQAEAKIATEK
                     GIHFYAVDVTKDKAGEEKNKFDDYLKKMSGDKGEFLNIDENVAEKFKDVLTKVSLVDS
                     LENDVEFAKKPDSSKVKITNGTSSLLWSFFSNSKTTITWNLDKEDLIKAYQTNKPLSL
                     TYQLQHKKNKKNKGFQELVRTEVRYSLNNDREKTAKYSSSKVSLNHETKKVLVPVPIE
                     PKDTDKVVDKSTGISKVENMTPMVTPEMPKQTEPNVPDSTLPMQPELPKETGKPGNNV
                     ETESPKPIENSTDDSANKPDSTTPKTTDNIIIPNPTLPMKPDSTEETEKPGNNVEPES
                     PKIIEDSTDDSANKPDSTIPKATDNIIIPNSTFPMKSESPKEIGETENSVKPESPKPI
                     EDTDSSAGTQKLDIPKVMDTPDLSRPMEPESTEEIGKAENSDTPDSSKTIKDSDNSAP
                     ISTIKDKVNAETVANQVELAMNQKSRLSDNVEKVSSVNRSTEKSNSLPSTGQADSPIY
                     TLTALSLLVGAQVLYRTKRKQESK"
     gene            complement(3854..4555)
                     /locus_tag="AC1PIV_001673"
     CDS             complement(3854..4555)
                     /locus_tag="AC1PIV_001673"
                     /EC_number="3.4.26.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family glutamic-type intramembrane
                     protease"
                     /protein_id="HIP6612679.1"
                     /translation="MWSPKKLTVLKWFDILILTIILFGDGIINSTLQYIALQNQTTTL
                     QENLTFSTMDNYKALALQLVWLTIAIFYLLLRNFDFSIWKKHIFITPWVPLQAVALFI
                     FSALCLDIYNLVSYQFLASNTPSMFQLFPNIDLSLILYSLLNGFYEEIFFLNLCLLVN
                     PKYAKWAFLYSLIIRCSFHTYQGLLSALGLGLILGTIFYLLYQKIKPKNLLPFFLAHA
                     VADVIGLTILSYILY"
     gene            4787..5437
                     /locus_tag="AC1PIV_001674"
     CDS             4787..5437
                     /locus_tag="AC1PIV_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HIP6612680.1"
                     /translation="MSRILVVEDDIVISQVVCEFLKEHGYQVESVFDGKVALERFQEE
                     QFDLIVLDIMIPSMTGLEVLKEIRKTSQIPILMLTAMGDEYTQLISFNQIISDYVVKP
                     FSPTILVKRIENILRGKGETDSIEIGTILIQPTSGAVYMEEEEVQLTKKEYEVLLYLA
                     KRRGKIVSRDNLMMGIWGYTELDSRVLDNHIKNIRKKLPSLPLKTIVGRGYQIEGT"
     gene            5439..6827
                     /locus_tag="AC1PIV_001675"
     CDS             5439..6827
                     /locus_tag="AC1PIV_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HIP6612681.1"
                     /translation="MGIARKNFIIVAAMISFISVTLLGLLYNAMPIYYNQVKKQELRH
                     DYMTVAKQLDGMPEAKIISEIDDFDIKTPNIIISLFSSDRKIIYPDPNDEMAKKHENE
                     YLENGDFDEIGSWGAEITSAEGVTYYLLFNYGFHSLSDVSQTLVTFYPFILLLIIVLA
                     VSVAFVYSRLSTRRIARISETTRRMQSLESGISCAVAGTDEITILAQDINSLYSKLLS
                     SIDELRTENERAMAREKEKSDFLRITSHELKTPIASMLGLVEGMIYNVGPFKDHDTYL
                     KKCKEILQEQSELVHSILEATNLDMALKESREQIRLDQLIDSSLTSYQSLAEVKGYQF
                     EVELSPVLIEANPVYFLKAIKNILDNAFRYSCKEAIIRVVLRQNQLIIENQVERVLSD
                     EELDQVFRPFYRPDYSRDKKDGGIGIGLFIVQKILEKHGFPYTFYASDTQTMRFMIHL
                     QSQSTANSNELI"
BASE COUNT         2440 a         1048 c         1343 g         2001 t
ORIGIN      
        1 caaacgatag agaaaaaaca aattctgttt ttaaattata tggtagaatg aattatgtag
       61 taatagactc gcacattttg tgatatggtc attgttaatg ataaatagga actttgagtt
      121 gtaatcatgc ttgcttgact tgataggtga agtaagcagt taacagaagg acttaggcac
      181 cttatgaata cacaaggtgc ccattctttt cccaaaagct ctacgcttct tgaacaaaat
      241 gatactaaag ttatttacca ttgacatcca tacttccttt tttgaaaata cctaaagaag
      301 ggcgaaaata cattctaaat ttatagagaa caaggagaag gaatcataat gaatcatcca
      361 aaattcactt tgcggaagct atcaattgga cttgtttcgc tgggagcggg ggtagcttta
      421 tcgggaacac tctatcctca aaatacagtg acagtatatg cagaaacgcc tgttacagaa
      481 agtactactt tagaaaaaaa atgaggagat agataatact tcttcgatta cacgtcctat
      541 tgctgttgaa gaccctaaag ttgtccaagc taatgaaaat aaggaaggag aggtggttga
      601 ctcctcttct attttctgcc ttaccaaaat cgaatgcaga atctgcttct cctgaggcat
      661 taacgaatga aaacgcttca gagccaacgg ggcaagttgc tgaaaacact agttcttctg
      721 aaggaaaagc aacagaaaaa gaagaaccag ccgttcagta tgtggagaag gaagtagatg
      781 actattctac taaggttgaa aaaccaaatg aaacagtatc tagtacagtg gataaaactc
      841 ctaaagagct ttttacagtt tctcgaacag cagaagtagg gcaagatgga gttgtcacag
      901 taacaactca aattgtgccg aaagaaattg ataagggtgc agaaatagtt gtcttggtgg
      961 atacatctaa aaaaatggat gaagaggcta aaaaagcagc taaagataac attgtcaagc
     1021 ttgtcaaaga aatgactgac ccaaccaata atcataattc tcgtaactct gtgcgtgtga
     1081 tcggtttcaa tcgcaagtta tctgaagctc aagaggttaa cagtattact gtagaagaca
     1141 cggttgagaa gcttttcact gatgctgaac aaaattacaa ttggggcgta gatatgcagg
     1201 gagcaatcca tgaagcacgt cgcattttag aaagcgagaa atcagggaaa cgcaaacata
     1261 ttgtacttct gtcacaaggg gagtctacat ttagttatga tttgacggat gctgcgaaaa
     1321 cagaaactaa gtataagaca atcaatgaag ataaagtggt gcatactaac cctctattgc
     1381 cttggccatt tacatttgat gtgactgtcc gcagagcaaa tttgttaaaa gatgccaaga
     1441 gcttgattga attcttgaat aaattgggaa ttacaaggtt taatgaggca ttagatggag
     1501 tatctactgt cgcaggttta actgacttta ttggaaagtt tttcagaaac ccgttagact
     1561 atattgactt agctgatatt gatagctcca aattagaaga acaaaaattc aattatgaga
     1621 aacaaattgg tgaggggtac catttccgta gcttttatga acgtaaactt gatccattac
     1681 catttaaaga cgctattgta aagaaaataa agtataattt aaaaaaagaa ttagataagg
     1741 ctgcattgcc tacaaatact ctcagttata tcggtaaaaa gattggtttg acaaatacct
     1801 ctgaaaaagc aattgacttg tttgcaaatt ccctcgttga ttacattttc tacggtcgaa
     1861 aaaatgtctt ttacaatcat aacctctctg ctcaggcaga agcaaagatt gctactgaga
     1921 aagggattca tttctacgct gttgatgtga ccaaagacaa agctggcgaa gaaaagaata
     1981 aatttgatga ctacttgaaa aaaatgtctg gggataaggg cgagttttta aatattgacg
     2041 agaatgttgc agaaaaattt aaagatgtat tgactaaagt gagcttagta gattcgcttg
     2101 aaaatgatgt tgagttcgcg aaaaaaccag atagttctaa agtaaaaatc acaaatggta
     2161 catctagttt attatggtcg tttttctcta actcgaaaac aactattact tggaacttag
     2221 ataaagaaga cttaatcaag gcttatcaaa ctaacaagcc actatcttta acatatcaat
     2281 tgcaacataa aaaaaataaa aagaataaag gtttccaaga attggtaaga actgaggttc
     2341 gttattctct taataatgat agagaaaaaa cagcaaaata ctcatcctca aaagtgtctc
     2401 ttaaccatga aactaagaaa gttttggttc ctgttcctat tgagccaaaa gatacagata
     2461 aggtggtaga caagtcaaca ggtatatcaa aagtagaaaa tatgacacct atggtgacac
     2521 ctgaaatgcc taaacagaca gaaccaaatg ttccagactc aactcttcca atgcaaccag
     2581 agttacctaa agagactgga aaaccaggta ataatgttga gacagaatca cctaagccta
     2641 tcgaaaactc aaccgatgat tcagcaaata aaccagactc aacaactccg aaaacaacgg
     2701 acaatattat tattccaaat cccactcttc caatgaagcc agattcaact gaagagaccg
     2761 aaaaaccagg aaataatgtt gaaccagaat cacctaagat tatcgaagac tcaaccgatg
     2821 attcagcaaa taaaccagac tcaacaattc cgaaagcaac ggacaatatt attattccaa
     2881 attccacttt tccaatgaag tcagagtcac ctaaagaaat tggtgaaaca gaaaacagtg
     2941 ttaaaccaga atcacctaag cctatcgaag atacagacag ttcagcaggt acacaaaaat
     3001 tggatattcc aaaagtaatg gataccccag atttgtctcg cccaatggaa ccagagtcaa
     3061 ctgaagagat tggtaaagca gaaaatagtg atactccaga ttcttctaag actattaaag
     3121 attcagataa ctctgctcca atttctacta tcaaggataa agtgaatgcc gaaacggtgg
     3181 caaatcaggt agagcttgct atgaatcaga aatcacgtct ttctgacaat gtggagaaag
     3241 tatctagtgt gaatcgttca accgagaagt caaactcgct tccatctact ggacaagctg
     3301 attctccaat ctatacgtta actgccctct ctcttcttgt aggagctcag gtactttatc
     3361 gtacaaaacg taagcaagaa tcgaagtaaa tgttggtcgt gtaatttcta cttgtatata
     3421 catatggtta atagagtaga gattatgcct ataatagtga tggaattgtt ttaccctccg
     3481 tacagatcca agttttagga aatctttgga gattgaatat aaaacgagcc attcgcaata
     3541 gctgcagagg ctgaactggg aatgtagaat aaatctgtca atctatacta ggctgagatg
     3601 agatatggac attgattctg agaagtatag ttgggcataa atataaattt caataaaaat
     3661 attgagataa gtcatataat aaaacgcata aaatcaacgt tcttagcaac acgattttat
     3721 gcgttttttg gcactctttt cctaaattac acaaaataaa ccacccgttt tcacgggtgg
     3781 tcatgactag taggggtcca ctcagtcttt ggtgatatga ggatagcttg tgttcaaatt
     3841 atctgttaga taactagtat agaatatatg atagaatagt taaaccgata acatcagcca
     3901 cagcatgtgc taggaaaaat ggtaataaat ttttaggttt tattttttga taaagtagat
     3961 agaaaatagt tcctagaatt aagcctaaac cgagtgcact aagtaaacct tgataggtat
     4021 ggaaactaca tcgaataatt aacgaatata aaaatgccca ttttgcatat ttagggttaa
     4081 ccagtaagca caagttaagg aagaaaattt cttcataaaa tccgttcaac aatgagtaca
     4141 agatcagtga taaatcaatg ttaggaaata gttgaaacat ggatggagtg ttggaagcta
     4201 gaaactgata ggatactaga ttatagatat ccaagcataa tgcagaaaaa atgaataagg
     4261 caacagcttg taatggaacc caaggagtaa taaaaatatg ttttttccaa attgagaaat
     4321 caaaatttcg gagtaataga tagaagatgg ctattgtgag ccaaactaac tgtagagcca
     4381 aagccttata attatccatt gttgaaaatg tcaaattttc ttgaagagtt gtagtttgat
     4441 tttgtaaggc tatgtattgg agagtagagt tgatgattcc atctccaaat aaaataattg
     4501 ttagaatgag aatatcaaac cattttaata cggttaattt ttttggactc cacataatgg
     4561 gatagttcct ttcatttttg tttagttcag tttatcaaac aaatctatat atgctctcgg
     4621 tttcgtctgt tttttatctg ttttaaacaa aagaagtcaa aagaaagctg aaatagcaga
     4681 acatggtgct ctatttatct atgatagagt tgcaccattg tacgaatcgg tatataattg
     4741 aagtataata atattttata atagaacttt acgaggaggt ataaaaatgt caaggatttt
     4801 ggttgtagag gatgacatag ttattagtca agttgtttgt gagtttttaa aagaacatgg
     4861 ttatcaggta gaatctgttt ttgatggaaa ggttgcttta gaaaggtttc aagaagaaca
     4921 attcgattta attgttttag atatcatgat tccatctatg acaggtttgg aagtactgaa
     4981 ggaaattcgc aaaacttctc agattccaat tttgatgctg acagccatgg gtgacgaata
     5041 tacacagctt attagtttta atcagattat aagtgattat gttgttaaac cattttcacc
     5101 aactatattg gtaaaacgga ttgagaatat tttgagagga aaaggagaga cagatagcat
     5161 tgagatagga acaattctta ttcaaccaac tagcggggca gtttatatgg aagaagaaga
     5221 agttcaattg acgaaaaaag aatatgaagt tttactatat ttagctaaac gacgtgggaa
     5281 aattgttagt cgtgataact tgatgatggg aatatgggga tatacggaat tggatagtcg
     5341 tgtcttagat aatcatatca agaatatccg taagaaattg ccgtcacttc ctttgaagac
     5401 aatagttggt cgtggttatc aaatagaggg tacttaatat ggggattgcc agaaaaaatt
     5461 ttattattgt tgctgcgatg atttctttca tctctgtaac attgttaggg ttattgtata
     5521 atgctatgcc tatatattat aatcaggtta agaaacagga attgagacac gattatatga
     5581 ctgtggctaa acaattggat gggatgccag aagctaagat tatatctgag attgatgatt
     5641 tcgacataaa aactccgaat attattatta gtcttttttc gagtgataga aaaattattt
     5701 atccagaccc caatgatgaa atggctaaaa agcatgagaa cgagtattta gaaaatgggg
     5761 attttgatga aattggttct tggggagccg agataacatc tgcagaagga gttacatatt
     5821 atctgttatt taattatgga tttcactcgt tatctgatgt cagtcaaaca ttggtaactt
     5881 tttatccatt catattgctg ttgattattg ttctggcagt ttcggtagct tttgtttaca
     5941 gtagactgtc cactcgtaga atagcaagaa tttcagaaac aacaagacga atgcaatcgt
     6001 tagagtctgg aatcagttgt gctgttgcag gaactgatga aataacaata ttggctcagg
     6061 atattaacag cctgtatagc aagttattgt caagtatcga tgaattaaga acggaaaatg
     6121 aacgtgctat ggcacgtgag aaggagaagt ctgatttcct ccgtatcaca tcacacgaat
     6181 taaaaactcc aatagctagt atgttggggt tagtcgaagg catgatttat aatgtggggc
     6241 catttaagga ccatgataca tatttaaaaa aatgcaagga aatcttgcag gaacaatctg
     6301 agttagttca ttctatttta gaagcgacaa atcttgatat ggctttaaag gaaagcagag
     6361 aacaaatccg attagatcag ttgattgatt cctctttaac aagttatcag agtttggcag
     6421 aggttaaggg ctatcaattt gaagtagaac tatcaccggt tctcattgag gcaaatcctg
     6481 tttatttctt aaaagctatt aagaatattt tagataatgc ctttcggtac tcatgtaaag
     6541 aggctattat tcgtgtagta ctacgccaaa atcaattaat aatcgaaaat caggttgaac
     6601 gtgttttaag tgacgaggaa ttggatcaag tctttcgtcc attctatcgt ccagactaca
     6661 gtcgtgataa gaaagatggt ggcataggga ttggtttgtt tattgtacag aaaatattag
     6721 aaaaacacgg ctttccgtac actttttatg cttctgatac acaaactatg cgttttatga
     6781 ttcatttgca atcacaaagt acagcgaata gtaatgaatt gatataggta aa
//
LOCUS       DBNFCO010000084         6802 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.084, whole genome shotgun sequence.
ACCESSION   DBNFCO010000084 DBNFCO010000000
VERSION     DBNFCO010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6802)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6802)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6802
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.084"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(31..573)
                     /locus_tag="AC1PIV_001676"
     CDS             complement(31..573)
                     /locus_tag="AC1PIV_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612682.1"
                     /translation="MFLFAFPGMGKTTLAKKYTDVVDLEMSDIKYDNSSVRHLTKEER
                     KSTKRPLKDKRYKTIYVNKGYTLHRQGKTVLVALNFLMRMLLAMSIRGGVPFHIYIPH
                     PSLKEEYRQRYISRGNNDRFIFEVMFIWYPALIPLYLLSKILPKWITVTQSGETLEDY
                     YKRENFVRFSQKLRFIQHIS"
     gene            complement(711..802)
                     /gene="ffs"
                     /locus_tag="AC1PIV_001677"
     ncRNA           complement(711..802)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="AC1PIV_001677"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(844..1365)
                     /gene="tadA"
                     /locus_tag="AC1PIV_001678"
     CDS             complement(844..1365)
                     /gene="tadA"
                     /locus_tag="AC1PIV_001678"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HIP6612683.1"
                     /translation="MNYTHEEKEYFMTQALQEARKSLEKDEIPIGCVIVKDGQIIGRG
                     HNAREELNQAIMHAEVMAIQEANNVEGNWRLLDSTLFVTIEPCVMCSGAIGLARIPQV
                     IYGATNKKFGAAGSLYDILTDERLNHRVKVETGILEAECANIMQDFFRQRRESQKAAK
                     LIMKTQEEATSDS"
     gene            complement(1645..3615)
                     /gene="tkt"
                     /locus_tag="AC1PIV_001679"
     CDS             complement(1645..3615)
                     /gene="tkt"
                     /locus_tag="AC1PIV_001679"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004802 - transketolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HIP6612684.1"
                     /translation="MSNLSVNAIRFLGIDAIEKSKSGHPGVVMGAAPMAYSLFTKELR
                     INPAQPNWVNRDRFILSAGHGSMLLYGLLHLSGFEEVTMDEIKNFRQWGSKTPGHPEF
                     GHTAGVDATTGPLGQGISTATGFAQAERFLAAKYNRDGFPIFDHYTYVICGDGDLMEG
                     VSAEAASYAGLQKLEKLIVLYDSNDINLDGETKDSFTEDVRARYNAYGWHTDLVTDGT
                     DVDAIFAAIEKAKVAGKPSLIEIKTVIGHGSPNKQGTNAVHGAPLGAEETEATRKALD
                     WNYGPFEIPAEVYADFKANVADRGAAAYDAWVKLVEDYKVAHPELAAEVTAILEGRDV
                     VEIKPEDFPVYENGFSQATRNSSQDALNAAAKVLPTFLGGSADLAHSNMTYIKEDGLQ
                     DSVNPLNRNIQFGVREFAMGTILNGMAAHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPIEHLAGLRAMPNLNVFRPADARETQAAWYLSLTSKS
                     TPSALVLTRQNLTVEEGTDFDKVAKGAYVVYEAAGFDTILLASGSEVNLAVKAAKELE
                     AAGTKVRVVSVPSTELFDAQDAAYKEEILPNAIRRRLAIEMGATQSWYKYVGLDGKVL
                     GIDTFGASAPAQTVIDNYGFTVENVVKLVGEL"
     gene            complement(3826..4917)
                     /gene="ulaG"
                     /locus_tag="AC1PIV_001680"
     CDS             complement(3826..4917)
                     /gene="ulaG"
                     /locus_tag="AC1PIV_001680"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_function: GO:0035460 - L-ascorbate 6-phosphate
                     lactonase activity [Evidence IEA];
                     GO_process: GO:0019854 - L-ascorbic acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HIP6612685.1"
                     /translation="MAKVQDITRESWILSTFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGVWIKTPGGANVVMDLWSSRGKSTKKVKDMVWGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHVHSDHMDISTAAAIINNPKLDHVKFVGPVESGDIWEKWGVPAD
                     RIIRIAPGDSFEFKDIKVHAVESFDRTCLVTLPIEGYDENGGKLAGLPVTDELMARKA
                     VNYVFETPGGTIYHGADSHFSNYFAKHGRDFNIDVAINNYGDNPIGIQDKMTSIDLLR
                     MAENLRAKVIIPVHYDIWSNFMASTDEILQLWKMRKERLQYDFHPFIWEVGGKYTYPM
                     DKDRIEYHHPRGFDDCFLEDSNIQFKALL"
     gene            complement(5027..6715)
                     /locus_tag="AC1PIV_001681"
     CDS             complement(5027..6715)
                     /locus_tag="AC1PIV_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HIP6612686.1"
                     /translation="MLLDKSSCALLRYLIGLQEPETIMAISKGLQQSRRKIYYHLEKI
                     NDALPTTVESIESLPRLGIRLTEAQKLACRDLLDSIDSYTYVMSMPERIQLMLVYICI
                     TPERVTIERLMELTEVSRNTVLNDLNEIRTQLAQEQYKMTLYVSKSHGYSLVCHPLNK
                     IQYVHSLLYTIFLDANKGFLQVLEAKLFELVGCQLLFSEEMAQFLQGQVSQLEKKLGK
                     KINRYEIEFMLKVLPFLLLSYRNMELDDLEERAILKEFEQVRERIEYRVAQELKDALL
                     QTFDLKLDEIEISLIAILLLSYRKDSDVHVFSQDFIDLKRVVERFIHHFEIHSPFELE
                     NPDELAKHLLAHCKALLFRKTYGILSKNPMVQQIQDKYSTLFAMTRVSGKILEEEWQI
                     ELSDGDIAYLTIHLGGAIRRSGTRKAQTQIVYLICDEGVSVQRLLYKQCQHHLPDKKI
                     GAVFTTEQFKSVEDLLEVDFLITTSDGLETDFPLVQVHPILDFDDVLNMTHFAKYRSL
                     ADEKQVFAVELDKLLSGYIADGRTARELKQRLQKLITNELLTNLSSQDIETDLY"
BASE COUNT         1868 a         1505 c         1375 g         2054 t
ORIGIN      
        1 ttcaagaaat ttatcaattt tcatttattt tcatgaaata tgttgtataa atcttaattt
       61 ttgtgaaaat ctaacgaaat tttcgcgttt gtaataatcc tccaaagtct ctcccgactg
      121 ggttactgta atccatttcg ggagaatctt agatagtagg taaagcggaa tgagggcagg
      181 ataccaaatg aacatgactt caaagatgaa ccggtcgttg ttgcctcttg aaatgtaacg
      241 ttggcggtat tcttctttga gagaagggtg gggaatatag atatgaaatg gtacaccacc
      301 gcgtatagac atggccagca acattctcat cagaaaattc agcgctacta ggactgtctt
      361 tccttgtcta tgaagagtgt agcccttatt gacatagatt gttttatagc gtttatcctt
      421 cagtgggcgt ttggtggatt ttcgctcctc tttcgttaaa tgacgaacac tgctattatc
      481 gtacttaatg tcagacattt ctaagtccac aacatctgta tatttcttag caagtgtcgt
      541 ttttcccata cctggaaagg caaataaaaa cataggcttt cctccttatt cctcagtaga
      601 atagcagagc atccaaaaag ttttcttaag ttgcccctat tttgcctctc atttctaaaa
      661 ataagccaaa gaaaaccctc tgaaagcctg atttcaaagg gttcttagat tatacgcaaa
      721 aagagcacac actcgacctc gcttagggct gctggattcc tcccctgacc cgcttcacgc
      781 acgaatgttg ctccatttaa tattataaca caatttggcc agagtgcaag tttggaatat
      841 taactagcta tccgaagttg cttcctcttg cgtcttcatg ataagtttag cagccttctg
      901 actttctctg cgttgtctga aaaaatcttg catgatattg gcacattccg cttctaaaat
      961 acctgtttct accttgacac gatggttgag ccgctcatct gtcagaatgt catagaggct
     1021 acctgcagct ccaaactttt tgttggttgc tccatagatg acctgcggaa tgcgtgctag
     1081 gccaatagct ccgctacaca tcacacaagg ttcaatcgtc acaaaaaggg tcgaatcaag
     1141 caagcgccaa ttcccctcaa cattgttagc ctcttggatt gccataacct cagcgtgcat
     1201 gattgcctga ttgagttcct cacgcgcatt atgccctctg ccaataatct ggccatcctt
     1261 gacaatcaca caaccaattg gaatttcatc cttttctagc gactttctag cttcttgcaa
     1321 tgcttgagtc ataaaatact ctttttcttc atgtgtatag ttcataaatc tattatagca
     1381 cagccctgat aacagttcaa aatcacttct ttattcgctg ctatcaaaat caatctaaca
     1441 ctacttcttc cttatcacac atttctttca aaattctgcc cttctattaa cttaaaaata
     1501 taaaaatacc tcctcagtcg agaaggtagg gggagcaata ttgattttta cagatattaa
     1561 tatatcattt attgtcgata ttgtcaagaa aatttttaaa aaaattcaaa aacagcctcg
     1621 aaaggctgta tctgacattt tctattacaa ttcgccaact aatttcacaa cattttctac
     1681 tgtgaagccg tagttgtcaa taactgtttg ggctggagct gaggcaccga atgtgtcgat
     1741 accaaggact ttaccgtcaa gaccgacata cttgtaccaa ctttgagttg cacccatttc
     1801 aattgccaaa cgacgacgga tggcatttgg aaggatttct tccttgtaag ctgcgtcttg
     1861 tgcatcgaag agttcagttg atggcacaga aaccacacga accttagtgc ctgctgcttc
     1921 taattctttg gcagctttga cagccaagtt cacttctgaa ccagatgcaa gaaggattgt
     1981 atcaaagcct gctgcttcat agacaacata agcccctttt gcaaccttgt caaagtctgt
     2041 tccttcttca actgtcaagt tttgacgagt gagaacaagg gctgatggtg tagacttgct
     2101 agtcaatgac aagtaccaag ctgcctgtgt ttcacgcgca tctgctggac ggaaaacgtt
     2161 gaggtttggc atagcacgaa gtcctgccaa gtgctcgatt ggttcgtgag ttggtccatc
     2221 ttcaccaact gcgatagagt catgagtgaa gacataagtc acaggaagtc cttgaagagc
     2281 tgacaaacga actgctgctt ttacatagtc tgagaagacg aagaaggtac caccatagac
     2341 acgaagtccg ccgtgggctg ccataccatt caagatagtt cccatggcaa attcacgcac
     2401 accgaactga atattgcggt tgagtggatt tactgaatct tgcaaaccat cttccttgat
     2461 gtaggtcatg tttgagtgag ccaagtcagc tgaaccaccg aggaaggttg gcaagacctt
     2521 agccgctgcg ttaagcgcat cttgtgatga gttacgagtt gcttgtgaga agccattctc
     2581 ataaactggg aagtcttctg gcttgatttc aactacgtca cgaccttcca agatagctgt
     2641 tacttcagct gctaattctg gatgagctac tttgtagtct tcaactaatt tcacccaagc
     2701 atcgtaggct gctgcaccgc gatcagctac attagctttg aagtccgcat agacttcagc
     2761 tggaatttca aatggaccat agttccaatc aagcgcctta cgagttgctt ctgtttcttc
     2821 tgcaccaagt ggagcaccgt gaacggcatt tgtaccttgt ttgtttggcg aaccatgacc
     2881 gataacagtc ttgatttcga taagagatgg cttaccagct acttttgcct tttcaatagc
     2941 agcaaagatg gcatctacat ctgtaccgtc tgttacaagg tctgtatgcc agccataagc
     3001 attgtaacgg gcacgtacat cttctgtgaa ggagtctttt gtttcgccat ccaagttgat
     3061 gtcatttgaa tcgtaaagaa cgatgagttt ttctaatttt tgaagacctg cgtaagaagc
     3121 cgcttctgca gaaacaccct ccatcaagtc gccatcacca cagattacgt aagtatagtg
     3181 gtcaaagatt gggaaaccat cacggttgta cttagctgca aggaaacgct ctgcttgcgc
     3241 aaaacctgtc gcagttgaga taccttgtcc aagaggacct gttgttgcat ccacacctgc
     3301 tgtgtgaccg aattctgggt gacctggtgt ttttgagccc cactgacgga agtttttaat
     3361 ctcgtccata gtcacttctt caaaacctga aaggtgaaga agtccgtaaa gcagcattga
     3421 cccatgacct gctgataaga taaagcggtc acggttcacc cagtttggct gagcagggtt
     3481 gatacgaagt tctttagtaa aaaggctgta ggccattgga gccgcaccca tgacgacacc
     3541 tgggtgacct gattttgatt tttcgatggc atcaatacca aggaaacgaa tcgcattgac
     3601 tgaaagattt gacatgtttt tctccttttt taaagtcatg aatttattat accataaagc
     3661 gttttctatg tctgtttgaa tgaagcgaga aataaattgt ccgtagaaaa gaggcaggac
     3721 tttcgtcccg cccttggagt gaacagtagt aattcgcaca tttcatactt tatcagagtt
     3781 tatagtgcct ctcctcgtct ctatggggca agagagttct aaatcttata ataaagcctt
     3841 aaattgaata tttgagtctt ctaagaagca atcatcaaag ccacgtgggt ggtgatattc
     3901 gatacggtcc ttgtccatcg ggtaagtata cttgccacca acttcccaga tgaatggatg
     3961 gaaatcgtat tgcaagcgtt ctttccgcat tttccagagc tgtaggattt catctgttga
     4021 cgccatgaag ttagaccaga tgtcgtagtg aacagggatg attaccttag cacgcaagtt
     4081 ttctgccatc cggagaaggt cgattgatgt catcttgtct tggataccga ttgggttgtc
     4141 accgtagttg ttgatagcaa cgtcgatgtt gaagtcacga ccgtgttttg caaaatagtt
     4201 tgagaagtgg gagtctgcac catggtagat agttccgcca ggtgtttcaa agacatagtt
     4261 gactgccttg cgagccatga gttcatctgt cacaggaagt cctgctaatt taccaccatt
     4321 ttcgtcataa ccttcgatcg gaagtgtcac caagcaagta cggtcgaagg attctacagc
     4381 gtggaccttg atgtctttaa actcaaagct atcgcctggt gcgatacgga tgatacggtc
     4441 agctggaacc ccccattttt cccagatatc gccactttca accggtccga caaatttcac
     4501 atggtccaat ttaggattgt tgatgatggc agcggcagtg ctgatatcca tgtggtcgct
     4561 gtggacgtgc gatactagat agtagtccaa ttcattgatg gcaaatggat cgataaccat
     4621 tggctgcaca cgcaagtttg gttgcaattt gcgcacgcca gccatgttag ccatctggtg
     4681 tccccaaacc atatctttca cttttttagt ggattttcca cgtgatgacc agaggtccat
     4741 gaccacgtta gctccacctg gtgttttaat ccagacacca cagtttccaa gccaccacat
     4801 agcaaagttg ccctctggca ctacttcttc ttcgatttct tcattgagcc aagttcccca
     4861 ctctgggaag gttgaaagaa tccaggattc tcttgtaata tcttgaactt tagccatttt
     4921 ccattcctcc tataaggtac gtttctatgc ttctagtata tgctccaaag gcaacaaaaa
     4981 aaagaccaaa taaaacacag gcttgtgttc aaacttggac tttaccctaa tacagatctg
     5041 tttcaatatc ttgactggat aaattggtta ataattcatt ggtaatcagt ttttgtagcc
     5101 gttgtttgag ttctcgagcg gtccttccgt ctgcgatata tcccgataga agcttgtcta
     5161 gttctactgc aaaaacttgt ttttcatctg ccaaactacg atattttgca aaatgagtca
     5221 tgtttagcac atcatcaaaa tctaaaatgg ggtgaacctg caccaaaggg aaatcagttt
     5281 ccaacccatc gctggttgta atcaagaaat caacctctag taagtcttcg acactcttga
     5341 attgttcagt ggtaaagact gcgccaatct tcttatctgg caagtgatgc tggcattgtt
     5401 tataaagtaa gcgttggact gacacccctt catcacagat taaatagaca atctgtgtct
     5461 gtgccttgcg tgtcccactg cgtcgaatag ctcctcctag atgaatcgtc aaataggcaa
     5521 tatctccatc ggataactca atctgccact cctcctccaa aatctttcca gaaacccgtg
     5581 tcatagcaaa cagggtgctg tatttatctt ggatttgttg gaccattgga tttttagata
     5641 ggatgccgta ggtttttctg aacaacagag ccttacaatg tgccaagaga tgtttggcta
     5701 attcgtcagg attttccaat tcaaatggtg aatgtatctc aaaatgatga ataaatcgct
     5761 ctaccactcg cttcaagtca atgaaatctt ggctgaatac atgaacatcg ctgtcctttc
     5821 gataggatag aagtaaaatg gcaatcaggg agatttctat ttcatccaat ttcaaatcaa
     5881 aggtttgcaa caaggcatct ttcaattcct gagcaactcg gtactcgata cgctctcgaa
     5941 cttgttcaaa ttctttgaga atggctcgtt cttccaagtc atccagctcc atattgcgat
     6001 agctaaggag caagaaaggc aatactttga gcataaactc gatttcgtag cgattgattt
     6061 tcttgcccag tttcttttct aactgcgata cttgtccctg taaaaattgt gccatttctt
     6121 ctgagaagag caactgacac cccaccaact caaataactt agcttctaga acctgcaaaa
     6181 aacctttatt ggcatccaag aagatggtat agagaagtga gtggacatat tggattttat
     6241 ttaaagggtg acaaacgaga ctatagccat gactcttaga cacatagagg gtcatcttgt
     6301 attgttcttg agccaactgg gttcgaattt cattcaaatc atttaagacc gtattacgag
     6361 agacttctgt caactccatt agccgttcaa tggtcactct ttctggtgtg atacagatat
     6421 ataccaacat cagctgaatg cgctcaggca tgctcatgac gtaggtgtac gaatcaatgg
     6481 aatcgagaag atctcgacag gctagttttt gcgcttcggt aagtcgaata ccgaggcgag
     6541 gtaagctttc aatactctct acagttgttg gtagggcatc attgattttt tctagatggt
     6601 aatagatttt tcgacgtgat tgttgcaagc ccttggaaat agccatgatt gtctcaggtt
     6661 cctgtagacc aatcaggtac ctcagtagag cgcaactact cttatctaat aacaagattc
     6721 tcctcctctt tcccccgtcc cgttactatc ttaacataat tatctgggat attctaataa
     6781 ttattaaaat tcatctgatt at
//
LOCUS       DBNFCO010000085         6727 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.085, whole genome shotgun sequence.
ACCESSION   DBNFCO010000085 DBNFCO010000000
VERSION     DBNFCO010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6727)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6727)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6727
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.085"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(179..5959)
                     /locus_tag="AC1PIV_001682"
     CDS             complement(179..5959)
                     /locus_tag="AC1PIV_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZmpA/ZmpB/ZmpC family metallo-endopeptidase"
                     /protein_id="HIP6612687.1"
                     /translation="MKRSLGEKRQRFGFRKMSVGLVSAAVTSLFFVSSVATAPTASAQ
                     SINYSYVTEQELTDGEKELIIRDLPGLAQETDVNYYLIYRPATGTTSTPSTSTSQVLP
                     NTGSVETELLVAGGVSLLLLAVRFGKKGKKELAGVILLTATGASFFGPTSSALTSQIL
                     ARYNHAIEISAGQALPAPAEIDGYVYVGYLKDSKAIEQTTSEEEKTAEFPASEGIRTE
                     TIVNKTEAIPFEIQTVENPQLSAGTERVVQEGQDGERIVTIKQVHSKGQIISEEEISS
                     TVTKTAVPKIVEVGTKQATDDIVTEVPDTEPSYENSTNSLTEETVTHTEVFAFDVQEI
                     YDVNLAEGSREVEQKGQDGVRTIETRNYYADGVLIKSEQVSDVVTKEPVTEVVRVGTK
                     TTDVIGSETIVTTEELPFETTVTETEELYVGEEKFITEGKVGSKEVTTTYQTINGVSQ
                     PNPTVTEKVLEEPTTKEVLKGTKPIEGTEIETNQVEITFETEYVDDPTLLEGKTKVVT
                     AGVNGSKTVTTTYQTIKGVRQENSTVTEEITKQPVKQVIARGTKVEKVPQVIITDLVE
                     NDDAKSATISYKLTDETANFQRAVALLYDNTGALVQEQTITDPNGQLTLENLDFYTDY
                     TVKTKIFYTMAEQEQSSEQEAILESMRKFDLVYKKIEIKDIDAVTVYRRKNGSYIGQE
                     FLEELPASTDELFIKVTSDRFKEVYLPVSSIEETTLNGKAVFKLVSSFDELVQDKDAQ
                     YVANREFYIPKMATDANTYTSFKALLDAMKANPSGTFKLGAHLDASEVPVGDVASYVT
                     NFSGTLDGLNDGYAFSISNLKAPLFFNLGGKVQNLDIKNASLNTSSKNPLATIAINAN
                     GATITNVAVEASIKGPQNVSGLVHSATNTTIKGVSFKGSIEVTGTNASLTGGILGNGT
                     MASVGNAKVDATITLPGTENQVAGGIVGRTMLVYDVPGSVYNSYAAGSIVTTESAAIV
                     GGIAGANQVTGAYAPHSGNVNNVVSDMTGTKSIIGQPANPTGKIKDGFTTTSDSLTNV
                     TVITDEEAQAKVEAMAIQATIDDSVPLNPNHYSVDYLTLDKAQADHETAYYNMEKILP
                     FYNKELLVYYGNKIATDDKLNKVRLLDVVPMKDNAVVADVYAEKANINKIMLHYADGT
                     VDYKTVSYLEDFKNNHVVEYTISGTDLIYTPESFLNDRSALVNDLVSSLSSVVLDSDA
                     MKAVINYPTTLNADTQTGTAKDFYFGESYDQVMTNLESNVRKILVASLNGQGQASEDY
                     IKEKIINNKAAFVLGLTYLNRWYDINFGEMNTKDLTIFEPDFFGNDAASALDMILAIG
                     NGGYDVLRAHNNVTTFASIIGKQNNQTKLFDMLEDYRQLFLPEMTNNEWFKQTTKAYV
                     VEGKSLIPEVAAKQETTDTYSKYNVGAYSKIVNDTVSNPTWKYNHMLLPLLTLPQENI
                     FIITNMNTIAIGSYEHYVDDYSTVENRDKVRQMVDLAAERQRDNADFWYKILDETNRD
                     KLFRSVLNNEGYVMYGKDGTKSYRNLTADVDAIQDFYGPINKWYREHPSIKTAFADGS
                     ETYYITYDMLTDYGTALYTHEMVHNQDGDIYLKGYGRRIGQGMEVYAQGLLQNVFNVT
                     EMNLGFNAVYNSDDANRVHVGDPVARFNSEADFNEYYHNQFDVLYLLDYLEGTNILAQ
                     SDANKKAWLRKIENYYVQNNGVDTHAGNSARALTDAEVASLKSFNDLIDQSIIVQRQY
                     VNNPTNTSKKWDRNSYVSVPMFAANFSALSNSNGSPGDIMFRRMAFELIAAKGYTDGF
                     VPYASGQLSDLAMEKGSIIYDTWNKKNTGLITDDHVLEYVFQGQYTSWAEFKKAMFTE
                     RLEKAATGQLKPFTMQYELGVADSTKEVTITSFEQLQNLMKEAMEADIQANSLNLNNS
                     RVHALKVKVYQALMNSTNDFRTSIFN"
     gene            complement(6132..6230)
                     /locus_tag="AC1PIV_001683"
                     /pseudo
     CDS             complement(6132..6230)
                     /locus_tag="AC1PIV_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261961.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UvrB/UvrC motif-containing protein"
     gene            complement(6273..>6727)
                     /locus_tag="AC1PIV_001684"
     CDS             complement(6273..>6727)
                     /locus_tag="AC1PIV_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF2971 domain-containing protein"
                     /protein_id="HIP6612688.1"
                     /translation="EDEGATDEIREIIDYIAKISYLFKVSDYQYESEYRILVNLDDTH
                     FTNKFTDKFTDKLNSGIKDEATRRKLDIGIGLLENKNVNYLNSRKYIHIEKTEQGKCN
                     LYAYINVVPLKYSKIMLGPKVENVDYIAPYIHYIQPDIIVETSSIPYR"
BASE COUNT         1812 a         1456 c         1277 g         2182 t
ORIGIN      
        1 tcctgaggta acaagtcagc ataggcctcc tgccatgatt tccaatgaac ataggccttg
       61 cctagcattt cacttttcgt ttccagtggt ttaatcatca tctaaaggac ctccgaattt
      121 tttcctctag tatacattaa aaaacaagtt ggcacaagac caacttgtta atgattattt
      181 aattaaaaat cgatgttctg aagtcatttg tagagttcat caaggcttga taaactttca
      241 ctttgagtgc atgaacacga ctgttgttca agttgaggct gttcgcttgg atgtctgctt
      301 ccatggcctc tttcatcaag ttttgcaact gctcaaagct tgtgatagtt acttccttgg
      361 ttgaatcagc aacaccaagt tcatactgca tggtaaacgg cttgagttgg cctgtcgctg
      421 ctttttccaa acgctcagta aacatggctt tcttaaactc agcccatgaa gtatattgac
      481 cttggaagac atattctaag acatggtcat ccgtaatcaa accagtattc ttcttgttcc
      541 aagtatcata gatgattgag cctttctcca tagctagatc agacaactgg ccagaagcat
      601 acggtacaaa accatctgtg taccctttgg cagcaattaa ttcaaaggcc atacggcgga
      661 acatgatgtc gcctggagaa ccgtttgagt ttgaaagggc tgagaagtta gctgcaaaca
      721 ttggaacgct gacataactg tttctatccc acttcttgct tgtgttagtt ggattgttga
      781 catattggcg ttgaacaata atgctctgat caatcaaatc attgaaggac ttcaagcttg
      841 ccacttcggc atctgtcaat gcacgcgcag aatttccagc atgggtatca acaccattat
      901 tttggacata gtagttttca atcttacgca accaagcttt cttgttagca tctgattgag
      961 ccaagatgtt tgtaccttct aggtaatcca gcaagtaaag tacatcaaat tggttatggt
     1021 aatactcatt gaaatcagct tcgctattga aacgtgcaac tgggtctccg acatggacac
     1081 ggttggcatc atcgctatta tagacagcgt tgaatccaag gttcatctca gtaacattga
     1141 agacattttg tagaagacct tgggcgtaaa cttccatacc ttgaccaata cggcggccat
     1201 agcctttcag ataaatatca ccatcttggt tgtgaaccat ttcgtgggta taaagagctg
     1261 taccgtaatc cgtcaacata tcgtaagtaa tatagtaggt ctcacttcca tccgcaaagg
     1321 cagtcttaat agacggatgc tcacgatacc acttattgat cggaccgtag aaatcttgga
     1381 tagcatcaac atcagctgtc aagttgcgat aagacttcgt accatcttta ccatacatca
     1441 cataaccttc gttattgagg acagatctga atagcttgtc acggttggtt tcatccaaaa
     1501 tcttatacca gaagtctgca ttatcacgct gacgttctgc cgccaaatca accatctgac
     1561 gaaccttatc acgattttca actgttgaat aatcatctac atagtgctca tatgaaccaa
     1621 tcgcgatggt attcatgttt gtgatgataa agatattttc ttgtggcaaa gtcaagagtg
     1681 gcaagagcat gtggttgtac ttccaagttg gattggatac agtatcattc acaatcttgc
     1741 tataagctcc aacattgtac ttgctatatg tatctgtcgt ttcctgctta gcagctactt
     1801 ctggaatcaa ggatttacct tcaacaacat aagccttggt tgtttgcttg aaccattcat
     1861 tgttggtcat ttctggcaag aagagctgac gataatcttc cagcatatcg aaaagcttgg
     1921 tctgattatt ttgtttacca atgatggatg caaaagtggt cacgttattg tgggcacgaa
     1981 gaacatcata gccaccatta ccaattgcaa gaatcatatc tagggcagat gctgcatcat
     2041 ttccgaagaa gtcaggttca aagatggtca agtctttggt attcatctct ccgaagttga
     2101 tgtcatacca acggttcaag taagtcaaac cgagcacaaa ggctgctttg ttgttgatga
     2161 ttttctcttt gatgtagtct tcagaagcct gaccttgacc atttagacta gccactaaaa
     2221 tcttacgaac attgctttct aggttggtca tcacttggtc atagctttca ccaaagtaga
     2281 aatcttttgc tgtaccagtc tgagtatcgg cattcaaggt cgttggataa ttgataacag
     2341 ccttcatggc atccgagtcg aggacaacag aagaaaggct gcttaccaag tcattgacaa
     2401 gggcacttct gtcattcaag aatgattctg gcgtgtaaat caagtccgta cctgaaatgg
     2461 tatactcgac cacatgatta ttcttgaagt cttctagata agaaactgtc ttgtagtcca
     2521 cagtgccatc agcatagtga agcataatct tattgatatt agccttctca gcgtagacgt
     2581 cagcaactac agcattgtcc ttcattggta caacatccag caaacggacc ttgttgagct
     2641 tatcgtctgt cgcaatcttg tttccataat agacaagaag ttccttgttg tagaatggca
     2701 agattttctc catgttgtag taggcagttt catggtcagc ctgtgcctta tccaaggtca
     2761 agtagtctac tgaataatga ttgggattaa gcggtacaga atcatcaatt gtcgcttgaa
     2821 tagccatagc ttctactttt gcttgtgctt cttcatcagt gataacagtg acgttggtca
     2881 agctatcaga tgttgtagtg aaaccgtctt taatcttacc agttggattt gcgggttgac
     2941 cgataatgct tttcgtacca gtcatatcgc tgacaacgtt gttgacatta ccgctatgtg
     3001 gagcataggc acctgttact tggttggcac cagcaattcc gccgacaatg gctgccgatt
     3061 cagtcgtcac aatggaacca gctgcataag aattatagac acttcctggt acatcgtaga
     3121 caagcattgt acgaccgacg ataccaccag ctacttgatt ctctgtacct gggagggtta
     3181 tggtcgcatc aaccttggca tttccgacac ttgccatcgt accgttaccc aagataccac
     3241 cagttagact tgcattggtt ccggttactt cgatactacc cttgaaggat acacctttaa
     3301 tagtagtatt tgttgcagaa tgaactaaac cagatacgtt ttgcggtcct ttgatagatg
     3361 cttctactgc tacgtttgta atagttgctc cattggcatt aatcgcaatt gtcgcaagtg
     3421 ggttcttaga gcttgtattc aggcttgcat ttttgatgtc caagttttga actttaccac
     3481 caaggttaaa gaacaatggt gctttcaagt tgctgataga aaaggcgtag ccgtcattta
     3541 agccatccaa ggtaccgcta aagttggtca catacgatgc aacatctcca acaggaactt
     3601 cacttgcgtc caaatgcgct cctagtttaa aggtaccact tggatttgcc ttcatagcgt
     3661 cgagcaaagc tttgaaggat gtgtaggtat ttgcatcagt cgccatctta ggaatgtaga
     3721 attcacgatt ggcaacgtat tgggcatcct tatcctgtac caattcatca aaggatgaaa
     3781 ctagtttgaa gactgccttg ccattcaagg tagtttcttc aatacttgac acaggtaggt
     3841 atacctcctt gaagcgatct gaagtcacct tgataaacaa ttcatctgtg gatgctggca
     3901 gttcttccaa gaattcttga ccgatgtagc taccattctt acgacggtaa acagtcaccg
     3961 catcaatatc cttgatttca atcttcttgt agaccaaatc aaatttgcgc atgctttcaa
     4021 gaatagcttc ttgttccgaa ctttgttcct gctctgccat tgtgtagaaa atcttagtct
     4081 taacagtgta atctgtgtag aaatcaagat tttcaagtgt caactggcca tttggatctg
     4141 taatggtctg ttcttgaacc aaggcacctg tattatcata gaggagagca acagctcgtt
     4201 ggaaattagc ggtttcgtct gtcaacttgt agctgattgt cgctgacttg gcatcgtcat
     4261 tttccaccaa atctgtgata atcacttgtg gtactttttc aacctttgta ccacgcgcaa
     4321 tgacttgctt aacaggttgt ttggtaattt cttctgttac agtagaattt tcctgacgaa
     4381 cacccttgat agtctggtaa gttgttgtaa ctgtcttaga gccatttaca cccgccgtta
     4441 caactttggt cttaccttct agcagtgttg gatcatcaac atactctgtt tcaaaggtaa
     4501 tctcaacttg attagtttcg atttccgtac cttctattgg ttttgttcct ttgagaacct
     4561 ctttcgttgt tggctcttca aggactttct cagtcactgt tgggtttggt tgactgactc
     4621 cgttgattgt ctgataagta gtggtaactt ccttagaacc aaccttacct tcagtaatga
     4681 atttttcttc cccaacataa agttcttctg tttctgtgac tgtcgtttca aacggaagct
     4741 cttctgttgt tacaatggtt tcagatccaa taacatctgt tgtcttcgtg cctactctta
     4801 caacttctgt tactggttct tttgtcacta catctgaaac ttgttcggat ttaatcagta
     4861 caccatcggc ataataattc ctagtctcga ttgtccgaac accatcttgt cccttctgtt
     4921 caacttcacg actaccttct gccaagttta catcatagat ttcttgcaca tcaaaggcaa
     4981 agacttcggt atgagtaact gtttcttctg ttaaagaatt cgtcgagttt tcataacttg
     5041 gttctgtatc tggtacttct gtaacaatat catcggttgc ttgttttgta ccaacttcaa
     5101 caatctttgg aacagcagtt tttgtaaccg tcgaggaaat ctcttcttcc gaaataattt
     5161 gaccttttga atggacttgt ttaatcgtta caatacgctc cccatcctgt ccttcttgta
     5221 ccactcgctc tgtccccgca gataattgag gattttctac ggtttgaatt tcgaatggaa
     5281 tggcctctgt cttgttgaca atagtttctg tacggattcc ttctgaagct gggaattccg
     5341 ctgttttttc ctcttccgaa gtagtttgtt caatagcttt gctatccttc aaatatccta
     5401 cataaacgta gccatcaatc tcagctgggg ccggtaacgc ttgtccggca gatatttcga
     5461 ttgcatggtt atatcgagcc aaaatttgac tcgtcaatgc ggagctagtt ggaccgaaga
     5521 agcttgctcc cgtagctgtc aaaaggatga cacccgccaa ctccttctta ccttttttac
     5581 caaatctaac agccaataac aggagagaca ctccacccgc caccaatagt tcggtttcta
     5641 cagagccagt atttggcaaa acttgagacg tgcttgtcga tggagtagat gttgtgccag
     5701 tagctggacg atagatcagg taataattta catccgtttc ctgagctaag ccaggcaagt
     5761 cacgaataat caactccttt tctccatctg tcaattcttg ctctgtcaca taggaataat
     5821 tgattgattg agcactagca gtcggtgctg ttgccacaga ggacacaaaa aatagacttg
     5881 tcactgccgc tgagacaagt cccactgaca tttttctaaa accaaagcgt tgtcgctttt
     5941 cacctaaaga tcttttcata taagttgtta ctccctaaaa tagtatagaa actattatac
     6001 ctattcaatg atgctcctac aagttttttg tcttattcaa tgaactattt tcaattcaaa
     6061 tctgatacaa actaagcaat gttcataaaa aacgacagga tgcagtaccc tgtcgcttta
     6121 ttctttcgaa tctacatatt cttcaactcg ataaccatat cacgaatctg ggctgccagt
     6181 tcaaagtcaa gcacttctgc cgcttcctgc atctgacctt ccagtttctt acttatggtc
     6241 taactcaatt cttcgtagct tttcaaaaga ggttatcgat acggaatact tgaagtttca
     6301 acgataatgt caggctgaat gtaatggata taaggagcta tatagtctac attttcaact
     6361 tttggcccca acataatctt tgaatatttt aatgggacaa cattgatgta cgcatataaa
     6421 ttacatttcc cttgttctgt tttttctatg tgaatatatt ttctgctgtt cagataattc
     6481 acattcttat tttctaacaa tcctatgcca atatctagtt tcctacgtgt agcttcatct
     6541 tttattccag agttcaattt atcagtgaat ttatcagtga atttgttagt gaaatgcgta
     6601 tcatctaagt ttaccaatat acgatattca gattcatatt gataatcaga aaccttaaaa
     6661 agataggata tcttagcaat ataatcaatg atttctcgaa tttcatcggt tgctccctca
     6721 tcttcta
//
LOCUS       DBNFCO010000086         6663 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.086, whole genome shotgun sequence.
ACCESSION   DBNFCO010000086 DBNFCO010000000
VERSION     DBNFCO010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6663)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6663)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6663
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.086"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            35..844
                     /locus_tag="AC1PIV_001685"
     CDS             35..844
                     /locus_tag="AC1PIV_001685"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018381403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family glutamic-type intramembrane
                     protease"
                     /protein_id="HIP6612689.1"
                     /translation="MKEKFQMCKTYLPVVLATIGFVNGCKIIFGELGKPNGMEAKYSL
                     FLLTISLVAIYLIPLLVLTYSLAKRYNISKQVIGLSWLLGLTSSISFSELGHTAIGYF
                     LLEIVKASNDFLNDWGAAISGPLAEEIGKGLTVLLVLLICRKMTLKNALVSGVIVGLG
                     FQIMEDITFVFRDMFMNKLDGFETILERVGQAGWAHWVFTLLFAIGLVALLTKNTGMS
                     KAQGVFWIGASFGIHFLFNSPFNTGIFQTVFPILSISLGLLAYRTVEKLSE"
     gene            complement(888..2558)
                     /locus_tag="AC1PIV_001686"
     CDS             complement(888..2558)
                     /locus_tag="AC1PIV_001686"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HIP6612690.1"
                     /translation="MKTDIDIAQSITLKPITEIVEKVGISFDDIELYGKYKAKLSFDK
                     INAVKDNAPGKLILVTAINPTPAGEGKSTITIGLADALSKIGKKTMIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHIHQGNVIGIDQRR
                     IIWKRVVDLNDRALRKVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDINDLKER
                     LANIVIGYRFDCSPVYVRDLAVEGALTLILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALRLADYTVTEAGFGADLGAEKFLDIKVPNLPKAPDAVVIVATLRAL
                     KMHGGVAKTELSAENVEAVKAGFSNLKRHVENIRKYGIPAVVAINEFVSDTAAEIAVL
                     KELCAAIGVPVELASVWANGADGGVELAETVVATIDNQAASYQRLYKSEDSLEEKVTK
                     IVTQIYGGTGVVFEKKARNQLTEFAKNGWDKLPVCMAKTQYSFSDDQFALGAPTDFDI
                     TVREFVPKLGAGFIVALTGDVMTMPGLPKAPVALNMDVAADGTAIGLF"
     gene            2960..3655
                     /locus_tag="AC1PIV_001687"
     CDS             2960..3655
                     /locus_tag="AC1PIV_001687"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HIP6612691.1"
                     /translation="MKLLITSGGTSEAIDQVRAITNHASGNLGKIIAEQALKRGHEVT
                     LVTTRQAVKPDSQKNLTIIEITNVDSLKETLEPLVKTHQALIHSMAVSDYTPVYMAGL
                     DELRATEDISSLLKKQNTESKISSKDDYQVLFLKKTPKVISYVKKWNPAITLFGFKLL
                     VNVPKEELFAVARQSIERNGADYILANDLKDIGENQHIAYLVDKTREIQAQTKDEIAQ
                     LILNTLEKGEQNG"
     gene            3648..4196
                     /gene="coaC"
                     /locus_tag="AC1PIV_001688"
     CDS             3648..4196
                     /gene="coaC"
                     /locus_tag="AC1PIV_001688"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HIP6612692.1"
                     /translation="MANITLAVTGSISAYKAADLTSQLTKIGHQVTVLMSRSAMDFIT
                     PLTLQSLSKNLVHTDVMIEENPTLIKHIDIAKETDVFLVAPASANTIAKLANGMADNI
                     ITATALALPIGTKKLLAPAMNTNMYLNPATQKNIKTLIEYGFEEIKPREALLACGDFG
                     TGALAEVTDILEKVSNTLDEKK"
     gene            4183..4752
                     /locus_tag="AC1PIV_001689"
     CDS             4183..4752
                     /locus_tag="AC1PIV_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HIP6612693.1"
                     /translation="MKKNKSTQIATIAIFFAVMIVINILSSIIFNILPVPIKPTIVHI
                     PVIIASIIYGPRVGACLGALMGLMSMTHNTIILLPTSYLFSPFVENGNVYSIIIAVVP
                     RILVGITPYFVYKWIKNRKGLFIAGAIGSMTNTIFVLGGIFFLFSSVFDGNIQAMLAT
                     VLGTNSIAEMIISSVLTAALVPTLQKIQK"
     gene            4843..6561
                     /locus_tag="AC1PIV_001690"
     CDS             4843..6561
                     /locus_tag="AC1PIV_001690"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002943598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HIP6612694.1"
                     /translation="MTYQETYQTWLDFADLPDYLREELVAMDEKTKEDAFYTNLEFGT
                     AGMRGYIGAGTNRINVFVVRQATEGLAKLVESKGEEAKKRGVAIAYDSRHFSPEFAFE
                     SAQVLAAHGIKSYVFESLRPTPELSFAVRHYNAIAGIMVTASHNPKEFNGYKVYGEDG
                     GQMPPADADALTNFIRAIDNPFAVELADLEASKENGLITVLGEETDVKYLEELNDLNI
                     NPELIAEYGKDMKIVYTPLHGTGEMLARRALAQAGFESVQVVEAQATADPDFSTVASP
                     NPESQAAFALAEELGREVGADVLLATDPDADRVGVEVRQADGSYWNLSGNQIGAIIAK
                     YILEAHKQAGTLPANAALAKSIVSTELVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMFGFEESFGYLIKPFVRDKDAIQAVLMVAEIAAYYRSRGMTLADGIDEIFKE
                     YGYFAEKTISVTLSGKDGAEQIKAIMAKFRDNSPAQFNATDIAVFEDFALQTKTDKDG
                     NIEKLTTPPSDVLKYTLADDSWFAVRPSGTEPKIKFYIATVGETLAEAEEKISNIEKE
                     INEFVG"
BASE COUNT         1994 a         1447 c         1296 g         1926 t
ORIGIN      
        1 gtacactagt ttattaatac agaaaggtca aactatgaaa gaaaaatttc aaatgtgtaa
       61 aacttatctt ccagtcgtct tagcaacgat tggatttgtc aacggttgca aaattatctt
      121 tggagaatta ggtaagccaa atggcatgga agctaaatat tctctctttc tcctaaccat
      181 ttccttggtc gctatctacc tcattcccct actagtactg acatattcct tagctaaacg
      241 ctataacatc tccaaacaag ttatagggct tagctggctt ttaggcttaa caagtagcat
      301 ctctttttct gaactgggac atacagctat cggatatttc ctgctcgaaa ttgttaaagc
      361 tagtaatgat ttcctaaatg actggggtgc agctatttca ggtccattgg cagaagaaat
      421 cggtaaaggg ctaactgttc tacttgtact gcttatttgt agaaaaatga cactaaaaaa
      481 tgcattggta agcggagtga ttgttggatt aggtttccaa atcatggaag acatcacctt
      541 tgtttttaga gacatgttca tgaataaatt agacggcttt gaaactattc ttgaacgcgt
      601 tggtcaagct ggttgggccc attgggtttt cacgcttctc tttgccattg gcttagtagc
      661 ccttctcacg aaaaatacag gtatgtcaaa agcacaggga gtattttgga tcggtgcaag
      721 ctttggaatc cattttctct ttaattcacc attcaacact ggtatcttcc agacggtgtt
      781 tcctatcttg agtatttccc ttggcttact tgcctatcga acggttgaga aactatctga
      841 atagacaaaa aatccgcctt tgagcggatt ttttatattc attcttgtta gaacaagccg
      901 atagctgtcc cgtctgctgc cacatccatg ttgagagcta cgggagcttt tggcaaacca
      961 ggcatggtca tgacatctcc agtcaaggca acgataaagc ctgcacccaa ttttggcaca
     1021 aattcacgga ctgtaatgtc aaagtctgtc ggcgctccaa gggcaaactg atcatctgag
     1081 aagctgtact gggtcttggc catgcagact ggcaacttat cccagccatt cttagcaaat
     1141 tcagtcagct ggttacgagc cttcttctca aagacaacgc ctgtaccacc gtagatttgc
     1201 gtaacaatct tggtcacttt ctcttctaag ctatcctcag acttgtaaag acgttggtag
     1261 ctggctgctt ggttatcaat agtagcaaca actgtctcag ccaattcaac accaccatca
     1321 gcaccatttg cccaaacact tgccaactcg acaggtacac cgattgcggc acagagttct
     1381 ttgagaacag caatttctgc tgcggtgtcg gacacaaatt cattaatggc tacaacagct
     1441 ggaataccat acttacggat attttccacg tggcgcttca agttagaaaa accagctttc
     1501 actgcctcta cattttcagc agaaagttct gtcttagcta caccaccatg cattttaagt
     1561 gcacggaggg tggcaacaat gactactgca tccggagcct taggcaagtt cggcacctta
     1621 atgtcaagga acttctctgc tccaaggtca gcaccaaatc ctgcttctgt gacggtatag
     1681 tccgccaaac gcagagctgt tgtggtagcg aggactgagt tgcagccgtg ggcgatgtta
     1741 gcaaatggac cgccatggac aaaggctggc gtgccataga tggtttggac aaggtttggt
     1801 ttaatagcat ccttcaaaat aagagtcaaa gcaccttcca ccgccaaatc acgcacgtag
     1861 acaggactgc aatcgaaacg ataaccgata acaatatttg ccaaacgttc tttcaagtca
     1921 ttgatgtctg tcgccaagca taaaatcgcc atgatttcag aagctacggt aatatcgaat
     1981 ccatcttcac gaggaatacc attgagcgga ccacccaagc caactgttac cttacgaagg
     2041 gcacgatcgt tgaggtccac aacacgtttc cagataatac gacgttgatc aatgccaatc
     2101 acattcccct gatggatatg gttatcaatc aaggctgaaa gggcgttgtt tgctgtggta
     2161 atggcatgca tgtcgcctgt aaaatgcaaa ttgatgtctt ccataggtaa gacctgagca
     2221 tagccaccac ctgcagctcc acctttgatc cccatgacag gtcccaaaga aggctcacgg
     2281 agggcaatca tggttttctt gccaatttta gacaaggcat ctgccaaacc gatagtaata
     2341 gttgatttac cttcaccagc tggcgttggg ttgatagctg tcaccaagat caatttccct
     2401 ggcgcattgt ctttcaccgc attgatttta tcaaaagaca attttgcctt gtattttcca
     2461 tatagttcaa tatcatcaaa actgatacca actttttcaa cgatctctgt gataggtttc
     2521 aaggttatac tttgtgcaat gtcaatatct gttttcatga gagtacctaa tttccttatt
     2581 ttttatggat attataccat actacaactt attttcgcat atttttttac tatttattca
     2641 ctaacgtacg gaattttcag aaaaactaca ggtttcctta cttaaacaga tacaaatttt
     2701 taaaaactgc attctcatca tagctctaca cttccatcta aggctggttt tagttagttt
     2761 tttcaaaaga gagtcagtat tcctttaaaa attgccttga ttaacaaacc aacgctttct
     2821 tgcacaaaaa cacttcacta tataatacag gcccttatat tttttgtatt agcagcatca
     2881 ttttccagtg tcacagattg attagcaaat agattagtac aaactttacg aaaaatagaa
     2941 attctagtaa aatatgaaca tgaaactatt gattacatca ggcggaacaa gcgaagctat
     3001 cgatcaagtc cgcgctatta caaaccatgc ttctggaaat cttggaaaaa tcattgccga
     3061 acaagccttg aaacgcggtc atgaagttac tcttgtgact acaagacagg ctgttaaacc
     3121 agattctcag aagaatttaa ccattatcga aatcacaaat gttgatagtt tgaaagaaac
     3181 attagaacct ttagtcaaaa cacatcaggc tctgattcat agcatggctg tatccgatta
     3241 tacacctgtt tatatggctg gtttagatga actaagagca actgaagaca tttctagtct
     3301 actaaaaaaa cagaatacag aaagtaagat ttcatccaag gatgactacc aagttctttt
     3361 cttgaaaaaa actcccaagg tcatttccta tgtaaaaaaa tggaatccag ctatcacact
     3421 ctttggcttc aaactattgg ttaatgttcc taaggaggaa ttatttgccg tagctcgcca
     3481 aagcattgaa cgaaatggcg ctgattatat acttgctaat gacttgaagg atattggaga
     3541 aaatcaacac attgcctatt tggttgataa aacaagggag attcaagcac agacaaaaga
     3601 tgaaattgct cagctcattt taaataccct agaaaaagga gaacaaaatg gctaatatca
     3661 cacttgccgt tactggctct atttcagcct acaaagcagc ggacctaact agtcaattga
     3721 ccaagatcgg tcatcaggtt acagtcctca tgagtcgctc tgctatggac ttcatcacac
     3781 ctttgactct ccaatccttg tcaaaaaatc tggtccacac agatgtcatg attgaagaaa
     3841 atcctactct tatcaagcat atcgatattg ccaaagaaac agacgtattt ttagttgccc
     3901 ctgcttctgc caatacgata gctaaattag ctaatggtat ggctgacaac attattacgg
     3961 caacagcgct ggctctgcca attggtacta aaaaactgct ggcacctgct atgaatacta
     4021 acatgtacct caatcctgct acccagaaaa atatcaaaac cctcatagag tatggttttg
     4081 aggaaatcaa accgcgtgaa gccctgcttg cttgtggaga ttttggaact ggggccttgg
     4141 ctgaggtaac tgatatttta gagaaagtga gtaacaccct tgatgaaaaa aaataaatca
     4201 actcaaattg ctacaattgc aatcttcttt gctgtcatga ttgtcatcaa tatattgagt
     4261 tcaattattt ttaatatatt gcctgttcca ataaaaccca ccatcgtaca tatcccagtc
     4321 attattgctt ctattatata cgggccacgt gttggggctt gtttgggggc tctcatgggc
     4381 ttaatgagta tgacccataa tactattatc ttactaccaa ccagctatct tttctcccca
     4441 tttgttgaaa atggtaatgt ttattcaatc atcattgcag ttgtcccacg tatattagtc
     4501 gggattacac cttatttcgt ctacaaatgg ataaaaaatc gtaaaggatt atttattgct
     4561 ggtgcaattg gttcaatgac caatactatt tttgtacttg gaggtatttt cttcctcttc
     4621 tcctctgtct ttgatggtaa tattcaagca atgttagcaa ccgttttagg taccaattca
     4681 attgcagaaa tgatcatttc ttctgtatta actgcagcgc ttgttccaac tttacagaaa
     4741 attcaaaaat aaatatcaga aaatcatgtg aaagcgtgat ttttcttttc aaacatggta
     4801 taatgaaagc gtttaataga aaaattttta aggagatatg cgatgactta tcaagaaacc
     4861 tatcaaacat ggctcgactt tgcggacctt ccagattact tgcgtgaaga attagtcgca
     4921 atggatgaaa aaacaaaaga agatgccttc tatacaaatc ttgaatttgg tacagctggt
     4981 atgcgtggct atattggcgc tggtaccaac cgcatcaacg tatttgtagt ccgtcaagct
     5041 actgaaggtt tggcaaaatt ggtagaatca aaaggtgaag aagctaaaaa acgtggtgtt
     5101 gccatcgctt acgattcacg tcacttctcg ccagaatttg cttttgaatc agctcaagtt
     5161 ttggcagcgc atggtatcaa atcttatgta tttgaaagcc ttcgtccaac tcctgagttg
     5221 tcattcgctg tgcgccatta caatgccatc gcagggatta tggtgactgc aagccacaac
     5281 ccgaaagaat tcaacggcta caaggtttac ggtgaagacg gcggacaaat gccacctgct
     5341 gatgcagatg cattgaccaa ctttatccgt gccatcgaca atccatttgc agttgaattg
     5401 gctgaccttg aagccagcaa ggaaaatggt ttgattacgg ttcttggcga agaaactgac
     5461 gttaaatatc ttgaagaact caatgacctc aacatcaacc ctgaattgat tgctgaatac
     5521 ggtaaagaca tgaagattgt ctatacaccg cttcatggta cgggtgaaat gttggcgcgt
     5581 cgtgcccttg cacaggctgg ttttgaatct gtccaagttg ttgaagcaca agcaactgct
     5641 gatcctgact tctctactgt cgcttcacca aacccagaga gccaagcagc ctttgccctt
     5701 gcagaagaac tcggccgtga agtcggggca gatgtccttc ttgcaactga ccctgacgct
     5761 gaccgtgttg gtgttgaagt tcgtcaagct gacggttctt actggaacct gtctggtaac
     5821 caaatcggcg ctatcattgc taagtacatc cttgaagccc acaagcaagc aggtacactt
     5881 cctgcaaacg ctgcccttgc taagtcaatc gtatctactg agttggtaac taagattgct
     5941 gaaagctatg gcgctaccat gttcaacgtc ttgactggtt tcaaattcat cgctgagaaa
     6001 atccaagagt tcgaagaaaa acacaaccat acttacatgt ttggtttcga agaaagcttt
     6061 ggctatttga ttaaaccatt tgtacgtgac aaggatgcta tccaggctgt gcttatggtt
     6121 gctgaaattg ctgcctacta ccgttcacgt ggcatgacct tagctgacgg tatcgatgaa
     6181 atcttcaaag aatacggcta ctttgctgag aaaacaatct ctgttaccct ttctggtaag
     6241 gatggtgcag aacaaatcaa ggcaatcatg gctaagttcc gtgataactc accagcacaa
     6301 ttcaacgcta ctgacatcgc ggtctttgaa gactttgccc ttcaaactaa gacagacaaa
     6361 gatggaaaca ttgaaaaact cactactcct ccatcagatg tcttgaaata caccttggca
     6421 gatgattctt ggttcgctgt tcgtccttcg ggaacagaac caaaaatcaa attctacatc
     6481 gcaaccgttg gtgaaacact tgctgaagca gaagaaaaaa tctccaacat cgaaaaagaa
     6541 atcaacgaat ttgttgggta agagtcacat aaattagaaa gttcaaacca cccgtcaaac
     6601 gggtggtttg aacaagggct ataagcccac atcaccagcc agcgcctaaa gacgctggct
     6661 ttc
//
LOCUS       DBNFCO010000087         6616 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.087, whole genome shotgun sequence.
ACCESSION   DBNFCO010000087 DBNFCO010000000
VERSION     DBNFCO010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6616)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6616)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6616
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.087"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(63..686)
                     /gene="nth"
                     /locus_tag="AC1PIV_001691"
     CDS             complement(63..686)
                     /gene="nth"
                     /locus_tag="AC1PIV_001691"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HIP6612695.1"
                     /translation="MVLSKKRARKVIEEIIALYPDAKPSLDFRNHFELVCAVLLSAQT
                     TDAAVNKATPGLFAAFPTPQAMAAAEVKDIEPYISRLGLYRNKAKFLKDCAQQLMERH
                     NGIVPQTREELEALAGVGRKTANVVLSVGFGIPAFAVDTHVGRICKHHDIVKKSATPL
                     ETEKRVMEVLPPELWLPAHQAMIYFGREVCHPKNPECEKFPQLYEFD"
     gene            784..1635
                     /locus_tag="AC1PIV_001692"
     CDS             784..1635
                     /locus_tag="AC1PIV_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002941443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HIP6612696.1"
                     /translation="MDLQELCRKVIQARPRNSHKGSYGRVLLIGGLYPYGGAIIMAAL
                     ASVNSGAGLVTVATEKDNIPALHSHLPEAMAFSFDDQALLISSLENADLVLIGPGFGE
                     NSRAEQLLDFVFEHLSDQQILVLDGSALTLVAKQNRKNFPCKQVILTPHQKEWERLSA
                     IPVADQTSQRNLEALQSFQENTILVAKSSATQILKTQPNQVTPIGAGGPYQATGGMGD
                     TLAGMIAGFAVQFPLVQLYERILVATYLHSYIADQLAQDYYLVKPTDVSRNIQKTMLQ
                     FQTQTTA"
     gene            complement(1817..6574)
                     /locus_tag="AC1PIV_001693"
     CDS             complement(1817..6574)
                     /locus_tag="AC1PIV_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HIP6612697.1"
                     /translation="MKKKETFSLRKYKIGTVSVLLGAVFLFAGAPSVAADELTSLVET
                     KVEATVPDVIVSESASESPVVEELVDTSVEATPTDVTTTDNVEETLGSEALENITNTE
                     VEATQPAVETPAISEKKVEEEEKLAVADETTAITNQEEAKPQNIDSNTIITVPKVWDS
                     GYKGEGTVVAIIDSGLDVDHDVLHISDLSTAKYKSEKEIEAAKEAAGITYGEWFNDKV
                     VFGYNYVDVNTVLKEEDKRSHGMHVTSIATGNPTQPVAGQLMYGVAPEAQVMFMRVFS
                     DLKATTGAALYVKAIEDAVKLGADSINLSLGGANGSVVNMNENVTAAIEAARRAGVSV
                     VIAAGNDGTFGSGHSNPSADYPDYGLVGAPSTARDAISVASYNNTTVGSKVINIIGLE
                     NNADLNYGKSSFDNPEKSPVSFEIGKEYEYVYAGIGQASDFDGLNLIGKLALIKRGTI
                     SFSEKIANATAAGAVGVVIFNSRPGEANVSMQLDDTAIAIPSIFIPLEFGEALASNSY
                     KIAFNNETDIRPNPEAGLLSDFSSWGLSADGELKPDLAAPGGAIYAAINDNDYANMQG
                     TSMASPHVAGAAVLVKQYLQATYPTKSPQEIEALVKHLLMSTAKAHVNKETTAYTSPR
                     QQGAGIIDTAAAISTGLYLTGEDGYGSITLGNVEDIFSFTVTLHNITNEDKTLNYSTQ
                     LTTDTVQNGLITLAPCLLAEIPGGKVTVKANSSTTVTINVDAASFAEELTGLMKNGYY
                     LEGFVRFTDVADVGDIVSIPYVGFRGEFQNLAVLEEPIYNLIADGKGGFYFEPVTAQP
                     DTVDISHHYTGLVTGSTELIYSTDKRSDFAIKTLGTFKNEAGYFVLELDESGKPHLAI
                     SPNGDDNQDSLALKGVFLRNYTDLVASVYAADDTERTNPLWESQPQSGNKNFYSGDPK
                     NPKSSIIYPTEWNGTDSEGNALADGKYQYVLTYSSEVPGAAVQTMIFDVIIDRESPVI
                     TTATYDETNFTFNPRPAIEKGESGLYREQVFYLVADASGVTTIPSLLENGDVTVSDNK
                     VFVAQNDDGSFTLPLDLADISKFYYTVEDYAGNISYEKVENLISIGNEKGLVTVNILD
                     KDTNSPVPILFSYSVTDETGKIVAELPRDAGDTSVLKLPFGTYTFDLFLYDTEWSSLA
                     GETKAVVTISEENSTAEVNFYVTLKDKANLLVDIDALLPSGSTIQLVTADGQTIQLPN
                     AKYSKTDYGKFVPVGTYTILPTLPEGYEFLEELDVAVLANQSNVKKLTLINKVALKEL
                     IAELAGLEETARYYNASPELQTAYAKALEDANAVYANKHNQVQVDSALANLVAAREQL
                     NGQATDKEKLIAEVSNYTPTQANFIYYNAENTKQIAYDTAVRSAQLVLNQENVTQAVV
                     NQALADLLAAKANLDGQKTDISALRSAVSVSSVLKATDAKYLNASENVKQAYDQAVEA
                     AKAILADESASQASVDQALAVLTSAQAELNGIATSTNDAKEPANTATDKKDEGTVTPP
                     PIDSEKVDVQAPPVKDTGNSGHVSIGQKPNPQPTLPRPVTLQASLSSPNQEKQVTQLP
                     NTGDNDTRYYLVLGVIIGLGTLLVSKRRHKEEV"
BASE COUNT         1840 a         1416 c         1324 g         2036 t
ORIGIN      
        1 tcagaattta ctcaaacaat tttacataaa aactaaaaaa atcttcaaaa acagaagatt
       61 ttttagtcaa attcatataa ttgtgggaat ttttcgcatt cagggttctt aggatggcaa
      121 acctcacgac caaaataaat catagcttga tgagcaggga gccagagttc aggaggtaag
      181 acttccatga ctcgtttttc tgtttccagg ggtgtagctg attttttgac aatatcgtgg
      241 tgtttacaaa tccgtcccac gtgggtatca actgcaaagg cgggaattcc gaaaccgaca
      301 cttaagacaa cattggccgt ttttcttccc actcctgcca aggcttctaa ttcctcacga
      361 gtttgaggga caatgccatt atgccgttcc atcaactgct gggcacagtc ttttaaaaac
      421 tttgccttgt ttcggtacaa acccaaacga gaaatataag gctcaatatc cttcacttct
      481 gctgccgcca tggcttgggg cgtagggaaa gctgcgaaca aaccaggtgt tgccttattt
      541 accgcagcat ctgtagtttg agcagataag agcactgcac ataccaactc aaagtgattt
      601 cgaaagtcca agctaggctt agcatcagga tatagagcga tgatttcttc aataactttt
      661 cttgcacgtt tttttgataa taccatgaat tcattatagc atgaaaactt ggatttatct
      721 aaaatctgga ttgtcataaa cctcattcct cgtggtataa taaaaagaaa agggggaata
      781 tgtatggact tacaagaact ctgtagaaag gtcattcaag caagaccacg caacagccat
      841 aagggaagct atggtcgagt cttgctgatt ggtggactgt atccctatgg tggagcgatt
      901 atcatggccg cactagcaag cgtcaacagt ggagcaggct tggtaactgt tgctactgaa
      961 aaagataaca taccagcctt acatagtcat ctgcctgaag ccatggcatt ttcatttgac
     1021 gatcaagcct tactgataag tagcttagaa aatgctgact tggtattgat tggtccaggt
     1081 tttggggaaa atagcagagc tgaacagtta ttggactttg tttttgaaca tttatctgac
     1141 cagcagattt tagttcttga cggctcagcc cttaccttag tcgcaaagca aaacagaaag
     1201 aacttcccgt gtaaacaagt catcctgaca ccccaccaga aagaatggga acggttatca
     1261 gccattccgg ttgctgacca aacaagccaa agaaatcttg aagccttgca atcttttcaa
     1321 gaaaatacaa tccttgtagc taaaagttcc gctactcaaa tcctaaaaac ccagccaaac
     1381 caagtcaccc caataggagc tggtggtcct taccaagcaa caggaggtat gggagatact
     1441 cttgcaggta tgattgcagg atttgctgta caatttcccc ttgttcaact atatgaaaga
     1501 atccttgtag caacctacct ccactcctat attgccgacc aactggctca agattattat
     1561 cttgtaaagc caactgatgt ctcaagaaac atccaaaaga caatgcttca atttcaaaca
     1621 caaacaaccg cctaatcaat gattaagcgg tcttttatat aacaaactcg tgattaaagc
     1681 ctgacaaatg gtagaaaatg atactcaatg caaatcaaaa gtagcctagg aaacgaagcc
     1741 gaagatagaa ctggagttca tcatggcaag ttgacaacgg ataattttga ttttcgaaga
     1801 gtatgactat attttcttag acttcttctt tatgacgtcg tttgcttacc aacagagtcc
     1861 ctagcccaat aatgacacca agaacaagat agtatctcgt atcattgtct ccagtatttg
     1921 gtagttgagt tacctgtttt tcttgattag ggctagatag actagcttgc aaagtgactg
     1981 gacgaggtaa agttggttga gggtttggct tctgaccgat cgatacatgc cctgaattcc
     2041 cagtatcttt tacaggaggt gcctgtacat caactttttc tgagtctata ggtggaggcg
     2101 ttacagtgcc ttcatctttt ttgtcagtgg cagtatttgc tggctctttg gcatcatttg
     2161 ttgaagtagc aataccattc agttctgcct gcgcgcttgt cagaacggct agagcttgat
     2221 cgacacttgc ttggcttgca gattcatcag ctagaatcgc tttcgctgct tcaactgcct
     2281 ggtcataagc ttgtttcacg ttttcagatg cattgagata cttagcatct gtcgctttta
     2341 atacggaaga aacggatact gcgctacgaa gggctgaaat atcagtcttt tgaccatcta
     2401 agttggcttt cgccgctaac aagtccgcca acgcttggtt gacaactgcc tgtgttacat
     2461 tctcttggtt caatacaagt tgtgctgaac gaacagctgt atcataggca atttgtttgg
     2521 tattttcagc attgtaataa ataaagtttg cctgagtcgg tgtgtagttt gatacttcag
     2581 caattagttt ttccttatcg gtagcctgac cgtttagctg ctctctcgct gccacaagat
     2641 tggcaagtgc tgaatctact tgtacctgat tgtgtttgtt ggcatatact gcattggcat
     2701 cttctaatgc tttagcatag gcagtttgaa gttctggact agcattgtaa taacgcgctg
     2761 tttcttcaag tcccgcaagt tcagcaatca gttctttcaa agcaacttta ttaatcaagg
     2821 ttaatttctt aacatttgac tggtttgcaa gtactgctac gtctaattct tccaaaaatt
     2881 catagccttc tgggagggtt ggaaggatag tgtaggtacc aactggtaca aatttaccat
     2941 aatcggtctt agaatattta gcatttggta gctgaatagt ctggccatca gcagttacca
     3001 gttggatggt tgaaccagaa ggtagtaatg catcaatatc taccagcaag ttggccttat
     3061 ctttcaaagt cacatagaaa ttcacctcgg cagtgctatt ttcttccgaa atcgtcacga
     3121 ctgctttggt ttcacctgct aggcttgacc attctgtatc atataagaat aaatcaaagg
     3181 tgtaagtacc aaatggtagc ttaagaacgc tagtatcgcc ggcatctcgt ggtaattctg
     3241 caacaatctt gcctgtttca tcggtgactg agtaagagaa aagtattggt acaggactat
     3301 ttgtatcttt atcaagaata ttgacagtta ccaacccttt ttcattgccg atactgatca
     3361 gattctctac tttttcatag ctgatgttac cagcataatc ctctactgtg tagtagaatt
     3421 ttgaaatatc tgcaaggtca agaggcaatg taaaggagcc atcgtcgttt tgtgccacaa
     3481 ataccttgtt atcagaaacg gttacatcac cattttctaa taaggaagga atagttgtca
     3541 caccgcttgc atccgctaca aggtagaata cttgctcgcg atatagaccg gattctcctt
     3601 tttcaatggc tggacgaggg ttaaatgtaa agtttgtttc atcataggta gctgtggtga
     3661 taactggtga ttctctatca atgataacgt cgaaaatcat agtttgtact gctgcacctg
     3721 gaacttcaga tgagtaggtc aaaacgtatt gatacttacc atctgctaaa gcatttccct
     3781 cgctgtctgt cccattccat tcagtagggt aaataatgct tgattttgga tttttaggat
     3841 caccactata gaagttctta ttgcctgact gtggttgact ttcccaaagt ggatttgttc
     3901 gttcggtatc atctgcagca tagacgcttg cgactaaatc cgtataattt ctcaagaaga
     3961 cacctttcaa agcgagcgaa tcttggttgt catccccatt tggcgagata gctaaatgag
     4021 gcttaccaga ctcatcgagc tctaaaacaa agtatcctgc ttcattttta aatgtaccta
     4081 gagtcttgat cgcaaagtca gatcgtttgt ctgtagaata gattaactcc gtacttcctg
     4141 taacaagacc tgtgtagtga tggctgatgt caacagtatc tggttgtgct gtaacaggtt
     4201 caaagtagaa gcccccctta ccatcggcaa taagattgta aatcggctct tctagaacgg
     4261 ctagattttg gaattcccca cggaaaccaa cgtatggaat gctgacaata tcaccgacat
     4321 cggctacatc tgtaaatcga acaaaacctt caagatagta accgtttttc attaaacctg
     4381 tcaattcttc tgcaaagctt gctgcatcga cattaattgt aacagttgta cttgaattgg
     4441 ctttcacagt caccttaccg ccaggaatct ctgctaatag acacggagcc aaggtaatca
     4501 atccgttttg aacagtatcc gttgttaact gtgttgagta gtttaaagtc ttatcttcgt
     4561 ttgtaatgtt atgaagtgtg accgtaaagc tgaatatatc ctcaacattt cccaaggtaa
     4621 tgctgccata accgtcttcg ccagtcaaat ataaacctgt agaaatagct gccgcagtat
     4681 cgatgatacc tgcaccttgt tggcgagggg aagtgtaggc tgttgtttct ttgttcacat
     4741 gtgctttagc agtagacata agcaagtgtt ttactaaggc ttcgatttct tgaggggact
     4801 tagtagggta agttgcctgt aaatattgtt ttactagtac ggctgctcct gctacgtgtg
     4861 gtgaagccat acttgttccc tgcatgttgg catagtcatt atcattgatg gctgcataaa
     4921 tagcaccacc tggagcagct aagtctggtt ttagctcgcc atccgctgat agaccccaac
     4981 ttgaaaaatc tgaaagaaga cctgcttctg ggttagggcg aatatctgtt tcgttattga
     5041 acgcaatctt atatgagtta gatgccaaag cttcaccaaa ttccaatgga atgaagatag
     5101 atggaattgc gatagctgta tcatccagtt gcatgctcac attggcttca cctgggcggc
     5161 tattgaaaat aacgacccct actgcccctg cagctgttgc attggctatt ttttctgaga
     5221 aactgatggt tcctcgttta ataagcgcaa gttttccaat caaatttaaa ccatcaaaat
     5281 ccgaagcctg accgattcct gcatagacat attcatattc cttcccaatt tcaaatgata
     5341 caggactttt ctctggatta tcgaacgaac tcttaccgta attcaaatca gcattatttt
     5401 ctaagccaat gatattaatt actttactgc caaccgttgt gttattgtaa gaagcgacag
     5461 aaattgcatc gcgagctgtt gaaggagctc cgaccaagcc ataatctgga taatcggctg
     5521 acggattaga atgacctgaa ccaaatgttc catcattacc agcagcaata acaacagaaa
     5581 cacctgcacg acgagcagcc tcgattgctg cagtcacatt ttcattcatg ttaacaacag
     5641 agccgttagc tcctcccagg ctgaggttga tgctatctgc acctaatttt acagcatctt
     5701 caatcgcctt tacgtacaat gctgcgcctg ttgtagcttt gaggtctgag aatacacgca
     5761 taaacatgac ttgcgcttca ggagctacac catacattaa ttgtccagcg actggttgtg
     5821 tcggatttcc tgtggcaata ctcgttacgt gcataccgtg tgaacgtttg tcttcttctt
     5881 tcaagacagt attcacatca acatagttat aaccaaatac aaccttatcg ttaaaccatt
     5941 cgccgtaggt aattcctgct gcttctttag ctgcttctat ctctttttct gatttatatt
     6001 ttgcggttga gagatctgaa atatgcaata catcgtggtc aacgtcaaga cctgaatcta
     6061 tgattgcaac tactgttcct tcgcccttgt aaccactatc ccaaacttta ggtactgtaa
     6121 tgattgtatt actatcaatg ttttgtggtt tcgcttcttc ctgattagta atagcagtag
     6181 tctcatctgc tacggcaagc ttctcctctt cttctacttt tttctctgaa atagctggag
     6241 tttctacagc tggttgagtc gcttctactt ctgtatttgt gatgttttca agagcttctg
     6301 agccaagtgt ttcctctaca ttatctgtag tggttacatc agttggggta gcctccacag
     6361 aagtgtcaac taactcctcg acaacgggac tttctgaggc tgattcgctg acgattacgt
     6421 caggaacagt tgcttccacc ttagtctcta caaggcttgt caattcatct gcagctaccg
     6481 atggtgcacc tgcaaacaaa aaaactgcac ccaaaagaac agacacagtt ccaattttat
     6541 acttccgaag tgagaaagtt tctttctttt tcataacttt tcctcctagt ttttctcctt
     6601 tattattggc aaagcc
//
LOCUS       DBNFCO010000088         6371 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.088, whole genome shotgun sequence.
ACCESSION   DBNFCO010000088 DBNFCO010000000
VERSION     DBNFCO010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6371)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6371)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6371
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.088"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            29..868
                     /locus_tag="AC1PIV_001694"
     CDS             29..868
                     /locus_tag="AC1PIV_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HIP6612698.1"
                     /translation="MNVLNIYNELDSHNFDLNVDHYGAEQCDKGYSFGPTIRDNFVLH
                     FITKGRGKILVDGKTSYLAAGDLFILPKDVSIFYQADDIDPWTYVWVGFSGSRAKDLL
                     NQSQLLENYYLHSNLESPILGYMHQINHVQMHPIPSITELVLIGYLNQLLAALIEEFP
                     SETLIKPETQTKHYVQQAIKMIHNHYAHPIKVSEIADFLALSRSYLYKIFKQETGYSI
                     KDYILQVKMNRSCQLLEDASRSITEIAYSVGYQDPLTFSAAFKNYFHISPTEFRKTQK
                     NKD"
     gene            complement(900..2060)
                     /locus_tag="AC1PIV_001695"
     CDS             complement(900..2060)
                     /locus_tag="AC1PIV_001695"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HIP6612699.1"
                     /translation="MTQYNFIDSPNRLSQHAEKWRQVETDKELLPLWIADMDFEPLPE
                     IRQVIRDYAVHHVFGYPYASDSLYQSIIDWEDRQHGYKIERESILLIEGVVPALSVAI
                     QSLTEEGDAVLINTPVYPPFARTVKLNNRQLVTNSLVDVDSIFRLNLDQLEKDIVENQ
                     VKLYIFCNPHNPGGRVWTREEVLAIGRLCQKHGVILVSDEIHQDLTLYGHKHYSFNTV
                     DESFKEFSIILSSATKTFNIAGTKNSFAIIENPSIRKTFAKRQLINNQHEIPTIGLLT
                     TEAAFTYGDEWLKELKVILERNIDFVEEYLTTHTRIKVMKPQGTYLIWLDFSAYELEY
                     AELFDILHCKAKLILNDGLTFGKEGKHHARLNVAAPFNMIEEACQRLGKVFG"
     gene            complement(2064..3155)
                     /locus_tag="AC1PIV_001696"
     CDS             complement(2064..3155)
                     /locus_tag="AC1PIV_001696"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HIP6612700.1"
                     /translation="MTDYKIDTILAHTGINSDERTGALISPIHLSTTYQHPEFGQSTG
                     YDYTRTKNPTRASLETTLAAIEKADYALATSSGMAALVLLFNGFPVGSQVVAARDLYG
                     GSFRWFNEQESIGRFQFTYANTEEELIAAITEETDYVYLETPTNPLMVEFDIAKVSAI
                     AHAKGVKVIVDNTFYSPIYQNPLVLGADVVLHSATKYLSGHNDVLAGALMTNDQALYD
                     KLFYDQNTSGPTLSPLDSYLLMRGLKTLSLRMERATQNAQKIVAYLEKSPAVKQVYYT
                     GKGGMISVKVVNESRIPHILNTLKVFTFAESLGGVESLITYPATQTHADIPAETRHSY
                     GLTDDLLRLSIGIEDAEDLIADLKTALEG"
     gene            3357..3623
                     /locus_tag="AC1PIV_001697"
     CDS             3357..3623
                     /locus_tag="AC1PIV_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612701.1"
                     /translation="MKFQFNKHFYRYSAFYSMIFWTCFFLSDILLDPSQTPAWYSLLA
                     CLIIFINAIWVFFFKEEKELTRMGYIFYIGLIVVIVYLRFILGK"
     gene            3637..3891
                     /locus_tag="AC1PIV_001698"
     CDS             3637..3891
                     /locus_tag="AC1PIV_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612702.1"
                     /translation="MSKKFNKAFYRTWEFYLSLACILQVIYAAVNGPFWFIHFLKLGV
                     GLYAGYLAFFKSRSWIKKTWQIYLTIGLIASWIIISFFVL"
     gene            3901..4152
                     /locus_tag="AC1PIV_001699"
     CDS             3901..4152
                     /locus_tag="AC1PIV_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009910501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612703.1"
                     /translation="MFKEFNKEYYRSLNFYLMILLFLGSIGEWLNKGPSLWLALLLFA
                     TVGTARSAFWSKEWTLKANWQIYLCIAFLLVGAWVEFFV"
     gene            4380..5129
                     /locus_tag="AC1PIV_001700"
     CDS             4380..5129
                     /locus_tag="AC1PIV_001700"
                     /EC_number="2.1.1.223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016430 - tRNA
                     (adenine-N6)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HIP6612704.1"
                     /translation="MQKIDLLDGERIDQLFSTDVQIIQNREVFSYSIDSVLLSRFPKM
                     PAQKGLIVDLCSGNGAVGLFASTRTKAQIIQVELQERLANMNRRSIALNGLEDQVSVI
                     NDDLANLPQYDLRSKVDLMLCNPPYFKVDKESNLNESEHYLLARHEIATNLDSICQVA
                     QQVLKSNGRLAMVHRPDRFLDILDTLRTYKLAPKRIQFVYPKASKEANMLLIEAIKDG
                     SVDGLHILPPLVVHEENGDYTPAIREIYYGK"
     gene            5119..5388
                     /locus_tag="AC1PIV_001701"
     CDS             5119..5388
                     /locus_tag="AC1PIV_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HIP6612705.1"
                     /translation="MENKAYLYVLECADGSLYTGYTTDVEKRLATHNRGKGAKYTRAR
                     LPVSLLYQEDFDSKQEAMSAEALFKKRSRQSKLDYIAERKQENAK"
     gene            5378..5746
                     /locus_tag="AC1PIV_001702"
     CDS             5378..5746
                     /locus_tag="AC1PIV_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005216 - monoatomic ion channel activity
                     [Evidence IEA];
                     GO_function: GO:0005267 - potassium channel activity
                     [Evidence IEA];
                     GO_process: GO:0034220 - monoatomic ion transmembrane
                     transport [Evidence IEA];
                     GO_process: GO:0071805 - potassium ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HIP6612706.1"
                     /translation="MQNKKHIHRLRIIWHILRVTGFATFLTSFFSFIFLAAGLLLWLE
                     PDFTSYGDSLWYSFVTATTVGYGDMLVTTAFGRIISIILAIYGILFLGSLSGLVVGYY
                     TEVSKHYSLAIKQDKQKTGS"
     gene            complement(5758..6369)
                     /locus_tag="AC1PIV_001703"
     CDS             complement(5758..6369)
                     /locus_tag="AC1PIV_001703"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008753 - NADPH dehydrogenase (quinone)
                     activity [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050136 - NADH:ubiquinone reductase
                     (non-electrogenic) activity [Evidence IEA];
                     GO_function: GO:0050446 - azobenzene reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HIP6612707.1"
                     /translation="MANLLIVKAHPLDAQKSYALRALEEFQTRYASLHPEDRIEIVDV
                     FEDQIPALDKPLLEAMGAAKRGEAISPEQAEQLGRYNALTQQFLAADKIVVVNPLWNL
                     NVPSQLVSWINTINVAGLTFKYGPEGSIGLVKGKKLLHIQSNGGVYAGQDPAAQYIKS
                     IFEFLGFEDIHQVFIEGQSADPSQSQVIFEEAMAKIDQILESY"
BASE COUNT         1811 a         1352 c         1293 g         1915 t
ORIGIN      
        1 tgttataatg tttcctagga ggattgaaat gaatgttcta aatatctata atgaattgga
       61 tagtcataat tttgacctaa atgtagacca ttacggtgcc gaacaatgtg acaagggcta
      121 ttccttcggt cctactatcc gtgataattt tgtcctacat tttattacaa aaggaagagg
      181 aaaaattctt gttgacggaa aaacaagcta tcttgctgca ggtgatttgt ttattctgcc
      241 aaaggatgtt tccattttct atcaagctga tgatatagac ccgtggacct atgtatgggt
      301 tggttttagt ggttcacgag caaaagacct acttaatcaa agtcaactgc tagaaaacta
      361 ctacctccac tccaatctag agtcaccaat tctaggctac atgcatcaga ttaaccatgt
      421 tcagatgcat cccatcccct ctatcacaga attggtctta attggctacc tcaaccaact
      481 cttagcagca ctcatagagg aatttcccag tgaaacatta attaagcctg aaacacaaac
      541 caagcactat gttcagcaag ccatcaagat gatccataac cactatgccc atccaattaa
      601 agtttctgaa atagcagatt ttctagcttt aagccgaagc tatctctata aaatttttaa
      661 gcaggaaact ggctattcta tcaaagatta tattttacaa gtaaaaatga atcgttcttg
      721 ccaactatta gaagatgctt ctcggagtat cactgaaatc gcctattctg tcggatacca
      781 agaccctctc accttcagcg cggccttcaa aaattatttc catataagcc cgacagaatt
      841 tagaaaaaca caaaaaaata aggattaggt gattttactc acacctagtc cttatttctt
      901 tatccaaaaa ccttaccaag tcgctgacag gcttcttcaa tcatgttgaa tggtgctgct
      961 acattcagac gtgcatggtg cttaccttcc ttaccaaagg tcaaaccatc attcaaaatc
     1021 aacttcgctt tacaatgaag aatatcaaag agctccgcat actctaattc ataggcagaa
     1081 aaatcaagcc agatgaggta ggttccctga ggcttcatga ccttgatcct tgtatgggtt
     1141 gtcaaatact cctcaacaaa gtctatattt ctctccaaaa taaccttcaa ctccttcaac
     1201 cactcatctc cataagtgaa agcagcttct gtggttaaca agccaatcgt tggaatctcg
     1261 tgctgattat ttatcaattg acgcttagcg aaagtcttgc gaatacttgg attttcaatg
     1321 attgcaaagc tattttttgt accagcgata ttgaaggtct tggtcgcaga tgataagatg
     1381 attgaaaact ctttaaaact ttcatccact gtgttaaagg aataatgctt gtgaccatac
     1441 aaggtcaaat cttgatgtat ttcatctgag acaaggataa caccatgttt ctgacaaaga
     1501 cgtccaatgg ccaacacttc ctctcttgtc caaactctac cacctgggtt gtggggatta
     1561 cagaaaatat agagtttcac ttgattctct acaatgtcct tttcaagctg gtcaagatta
     1621 agcctaaaaa tactatctac atcaactagt gaattggtca ccaactgacg attgtttaat
     1681 tttacagtcc gcgcaaaggg tggatagaca ggtgtattaa ttaggactgc atccccttct
     1741 tctgtcaaag attgaatagc cacagataag gcaggaacaa ctccttcaat gagtagaata
     1801 gactctcttt caatcttata gccatgctgt ctatcttccc agtcaataat agactgatag
     1861 aggctgtcac tagcataggg ataaccaaaa acgtgatgaa ctgcgtagtc acggataact
     1921 tggcgaattt ctggtagagg ctcaaagtcc atatctgcta tccacaaggg taagagttct
     1981 ttatccgtct ctacttgtct ccatttttcc gcatgctggg atagacgatt cggactatct
     2041 ataaaattat actgtgtcat atcttatccc tccaaggctg tctttaaatc tgcaatcaag
     2101 tcttccgcat cctctatacc aatagacaga cgaagcaaat catctgtcaa accgtaagaa
     2161 tgacgggttt cagctggaat gtctgcgtgg gtctgagtgg ctggataggt aatcagactc
     2221 tctactccac ccagactttc agcaaaggta aagactttca gggtgttgag aatatgggga
     2281 atccgacttt catttaccac cttaaccgaa atcatcccac cttttcctgt gtagtaaact
     2341 tgcttgactg ctggactctt ctccaaatag gcaacaattt tctgagcatt ttgtgtcgcc
     2401 cgctccattc gaagcgagag ggttttgagt ccacgcatga gtaagtaaga atccagtgga
     2461 gatagggttg gacccgatgt attttggtca taaaagagct tatcatatag ggcttgatca
     2521 ttggtcatca aagcgccagc tagtacatca ttatgcccag ataggtactt ggttgctgaa
     2581 tgtaggacaa catccgctcc tagaacaagt ggattttgat aaatagggct gtaaaaagtg
     2641 ttatcgacaa tcaccttaac acctttggca tgggcgatag ccgaaacctt agcgatgtca
     2701 aactccacca tgagtgggtt agtcggtgtc tccagataaa catagtctgt ctcttcggtg
     2761 atggctgcaa tcagctcctc ctcggtgttt gcataggtaa attgaaatct accgatactc
     2821 tcttgctcat tgaaccagcg gaaggaacca ccgtacaaat cacgcgccgc taccacttga
     2881 ctccctacag gaaaaccatt aaaaagtaag accagagcag ccattcccga gctcgttgct
     2941 agggcatagt cggccttttc aatagctgcc aaagtcgtct ctagactggc acgtgtcgga
     3001 ttttttgttc tcgtgtagtc ataacctgtc gattgaccaa actcagggtg ttgataggtc
     3061 gtcgaaaggt ggatagggga aatcaaggca cctgttctct catcgctatt gatgcccgta
     3121 tgcgctaaaa tcgtatcaat cttataatct gtcataacat ctactccaat ctaacttaca
     3181 atatagtcta gcatgaaata ggagatttgg tgtgaaaaat atccaaaaat acttatagaa
     3241 aaatagcaag ctttgttata gtttttcttt ataacaatat ccatactgga tctaccaata
     3301 aatactttta aacctataat ttatttgata taataaaaga aagagaggtg attgtcatga
     3361 aattccagtt taacaagcat ttctatcggt atagtgcctt ctattctatg attttttgga
     3421 cttgtttttt tctgtcagac attttgctag acccttccca aactcctgca tggtatagcc
     3481 tactagcctg tctgattatt tttatcaatg ccatttgggt attcttcttc aaagaagaaa
     3541 aggagctcac tcgcatgggt tacatcttct atatcggatt gattgtagtg attgtttatc
     3601 tgagatttat tttaggtaag tagaaaggag tttactatgt ctaagaaatt caataaagca
     3661 ttctatcgga cctgggaatt ttacttgtct cttgcctgta tcctacaagt gatttatgct
     3721 gctgtaaacg gaccgttttg gtttatccat tttctcaagc ttggagtcgg actttatgct
     3781 ggttatctag ctttctttaa gtcacgtagc tggataaaaa aaacatggca aatttatctg
     3841 acgattggat tgattgctag ttggataatc atttccttct ttgtattgtg aggattttat
     3901 atgtttaagg aatttaataa agaatattat cggagtttga atttttatct gatgatattg
     3961 ttgtttctag gaagtatcgg ggagtggcta aataagggac ctagcctctg gcttgcactc
     4021 ttgctctttg ctactgttgg tactgcccgt agtgcctttt ggtctaaaga atggacctta
     4081 aaagcaaatt ggcaaatcta tctctgtatc gccttcttgc ttgttggagc ttgggtagaa
     4141 ttttttgttt aagagttggg agtgggaaag aactcgacta agtcaaaaag agttcgtatt
     4201 cccacccccg cacagttgat taggtcagat ttggagtgta aaacacgaac aaatctgcca
     4261 atcaaccact gcgctgagat gttgacacga acactgagaa gtgggccagg gctttttgcc
     4321 cagcctcttt tctttcaaaa taaacagtga ttttcattca aagatggtat aatataccta
     4381 tgcaaaaaat tgatttacta gacggagagc ggattgacca gctcttctcg acagatgttc
     4441 agattattca aaatcgggag gtatttagct actcgattga cagcgttctt ctttcgcggt
     4501 ttccaaaaat gcctgctcag aaggggttga ttgttgacct ttgtagtgga aatggggcgg
     4561 tgggtctctt tgcttctaca cgcaccaagg ctcagattat tcaggtcgag ttgcaggaac
     4621 gcttggcgaa tatgaaccgc cgctccattg ccctcaacgg tctggaggat caggtttcgg
     4681 ttatcaatga cgacttggca aatctacccc aatatgacct acggtccaag gttgatttga
     4741 tgctctgcaa tcctccctac ttcaaggtgg ataaagagtc aaacctcaat gaaagcgagc
     4801 attatctcct agccagacat gagattgcaa ccaacctaga cagcatttgt caggtggccc
     4861 aacaggtgct caagtccaat ggtcgcttgg ccatggttca cagacccgac cgatttttag
     4921 atattttaga cacactaaga acctacaaat tggctcccaa acgcatccag tttgtctatc
     4981 ccaaggccag caaggaggcc aatatgttgc tgattgaggc tatcaaggac ggctcggtgg
     5041 acgggctgca catcctgcca cctctggttg tccatgagga aaacggcgac tatacacctg
     5101 ccattcgtga gatttattat ggaaaataag gcctacttgt atgttttgga atgtgccgac
     5161 ggaagtcttt atactggtta tacgactgat gtggagaagc gacttgctac ccataatcgt
     5221 gggaaagggg ccaagtacac ccgcgcacgc ttgcctgtca gcctgctcta tcaggaagac
     5281 tttgacagca aacaggaagc tatgtctgcc gaggctttgt ttaagaaacg cagtcggcag
     5341 agtaaattag attatattgc agaaagaaaa caagaaaatg caaaataaaa aacatatcca
     5401 ccgccttcgc atcatttggc atatcttgag agtgactggt tttgccactt ttctcacttc
     5461 ctttttcagt tttatctttc tagcagctgg tttgctactc tggttggagc ctgattttac
     5521 cagctacggt gatagtttat ggtacagctt tgtaacggcg acgactgttg gctatggaga
     5581 tatgctggtc accactgctt ttggacggat tatcagcatt atcttagcta tttacggcat
     5641 tctctttttg gggagcctgt ctggattagt cgtcggctac tataccgagg tcagcaagca
     5701 ttattcttta gcaatcaaac aggacaagca aaaaactggc tcttaggaac cagtttttta
     5761 atagctttcc aaaatctgat caattttagc cattgcctct tcaaaaataa cctgagactg
     5821 acttggatcg gcagattgcc cttcgataaa gacctgatga atgtcttcaa atccaagaaa
     5881 ctcaaagata gacttgatat attgggcagc tggatcttga cctgcataaa caccaccatt
     5941 ggactggatg tgcaacaatt ttttgccctt gaccagaccg atagagccct caggtccata
     6001 cttgaatgtc agtcctgcaa cgttaatggt attgatccat gacactaatt gacttggcac
     6061 attgaggttc caaaggggat tgaccacgac aatcttatct gctgcaagaa attgttgggt
     6121 caaggcattg tagcggccca actgctctgc ttgttcaggg ctgatagctt cgcctctttt
     6181 agctgctccc atagcctcta acaagggctt atccaaagct ggtatttggt cctcaaagac
     6241 atctactatt tcaatccgat cttctgggtg caaactggcg taccgtgttt gaaactcttc
     6301 caaagcccgc aaggcgtagg acttttgtgc gtcaagtggg tgggctttta cgattaatag
     6361 atttgccatt g
//
LOCUS       DBNFCO010000089         6359 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.089, whole genome shotgun sequence.
ACCESSION   DBNFCO010000089 DBNFCO010000000
VERSION     DBNFCO010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6359
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.089"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            <1..303
                     /locus_tag="AC1PIV_001704"
     CDS             <1..303
                     /locus_tag="AC1PIV_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HIP6612708.1"
                     /translation="SSILIEFLVLAIVEKQDSYGYEISQTIKIVADIKESTLYPILKK
                     LEKAGYVTTYTQEFQGRKRKYYTITPAGREHIPFLQGEWNSYKDHIDGIIEGSLRK"
     gene            300..1412
                     /locus_tag="AC1PIV_001705"
     CDS             300..1412
                     /locus_tag="AC1PIV_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat-containing
                     protein"
                     /protein_id="HIP6612709.1"
                     /translation="MTRADYLNQLEQALFQLHPSARQEALDYFNEYFDEKDNDEEAII
                     ELGTPDEAAKEIIANLPEDALITEQDQASPHSSKPFDFNFDFDFQFDWENFFNNFKHS
                     AYQARERIKLTAKIEELPEFSNLQISLEDQALSVQSYNGEAVLLHNPVSEDGSYQAFD
                     YQLVQDSLYLTSKPTPNHLYFSNNQTSSAILKIPKKLLPLTSLNLKTTDSSLTMAAVQ
                     ASEQLVINAKDSSISMTKVSCPSSALRLEDSTLTISDGQMSELKLEASDAVITLSSMS
                     LSDARITLEDCVWKLKDFVIEKSLNCQAEDSVLTYKPSTDISLDIWEEDSSLKLPKDK
                     AFTMMKEGDITHLSYKQENSPAQLVIHCQDCQLSVG"
     gene            1424..2002
                     /locus_tag="AC1PIV_001706"
     CDS             1424..2002
                     /locus_tag="AC1PIV_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HIP6612710.1"
                     /translation="MNRKEYLQKLEKYLKNLPKEDFQDTLDYFNEYFDEKENDEQAIQ
                     ELGSPKEAAHEILANLYDKEKTEDKPNTRNMVWLTILSILAAPIGVPLAITLVALFIT
                     LLLIIFSLFLLLISLWIVLLSLAIAQLLLAFDLFTLSWSTSLLFTGLALICLALTLLG
                     SKFTLDLGSKTFLLVLHWIQRKIRKGGYYETA"
     gene            1989..2843
                     /locus_tag="AC1PIV_001707"
     CDS             1989..2843
                     /locus_tag="AC1PIV_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014917252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat-containing
                     protein"
                     /protein_id="HIP6612711.1"
                     /translation="MKQLKPFTKISLSLFTLGTILSLIGYLAGGWTNMKTVAENYFQP
                     QTASFTDIRSIEVNEKLSIMPSPDKQFHLHYYRNQHKGIDLLSHQVQDGKLTISSAYQ
                     GIVTYDGLLEPILNLVNDQNVAYYQPVLQVPKNSTIETLSGSIQGDVYLDKVTIQDFQ
                     LFVENGDMLIENSQLSFAHLSHLNGEVAINHSTLISPKDISDTVGSSLTIEDGDFKAE
                     NLKLEGRHSISNYGGSIDISLHSKTKTDIHIDASQNNLGIDLPTYSNPQSTNYLNIST
                     LDGELSIR"
     gene            complement(2880..3239)
                     /locus_tag="AC1PIV_001708"
     CDS             complement(2880..3239)
                     /locus_tag="AC1PIV_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HIP6612712.1"
                     /translation="MSIFTTILASIVAIEHLYIMYLETFATHSDSTSRVFNMEKEELQ
                     RKSVTALFKNQGIYNGLLAVFLFYGIFTGNLEITSIFVLCVIAAAAYGAITASPKIIL
                     TQGGPAILALISILLFK"
     gene            complement(3259..3684)
                     /locus_tag="AC1PIV_001709"
     CDS             complement(3259..3684)
                     /locus_tag="AC1PIV_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HIP6612713.1"
                     /translation="MQEMEDLLYRLKVTDETISNLFEKQLGISLTRYSILQTLLKDAP
                     LHQLALQERLQIDRAAVTRHLKLLEESGYIIRKRNPDNQREVLVWPTEQAREALITNP
                     SAHHQAIKASMNQILTVEESEQFLATLDKLLIGLQNLPI"
     gene            3846..4604
                     /locus_tag="AC1PIV_001710"
     CDS             3846..4604
                     /locus_tag="AC1PIV_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HIP6612714.1"
                     /translation="MENTPRLNLVIDVLMLAGAILAQSGAEIHRVEDTMIRIAHSQGI
                     EQANVLAIPAAIFFSIDHTNISRMKRIVNSNYDMQKVCDVNQISRSLANEEISLEEAW
                     SQLNAIKQQKPPYNNIQITLAAVVAAPFFTIMFGGSLLDAAGAVLATALAFPISLIVE
                     RYIGIDFVTTFVGAFVFSLTSYLLSATTTLPINPNLINAGAVMPFVPGIAFTNAVRDL
                     MTNHINTGMTKFFQTALIILSLGAGTTVAFMLVR"
     gene            4608..5060
                     /locus_tag="AC1PIV_001711"
     CDS             4608..5060
                     /locus_tag="AC1PIV_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HIP6612715.1"
                     /translation="MTPVHFLLQALASYIAIAAFLIVLNVQRKMLVPGGLLGMLVWLI
                     YLSLLGPTNVLIATFFAAIIGSCVSQIMSIWLKTPSVIFSLAILAPLVPGYRAYMTTT
                     YFVSGDHAQALTNITTVLTLALVIPIGMASGTILLHLYKVLRTGKKAA"
     gene            5117..6355
                     /locus_tag="AC1PIV_001712"
     CDS             5117..6355
                     /locus_tag="AC1PIV_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009910001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HIP6612716.1"
                     /translation="MNQNVTNLKLAERGALLSIGAYIVLSGIKLVAGQLFHSDALRAD
                     AFNNISDIIGNIAVLVGLKMAQKPADTDHKFGHWKMEDLASLITSFIMFVVGFQVLYD
                     TLQKLISNSSIEVDIMGAIVGIFSALVMLAVYLYNNRLAKKVRSKALEAAAKDNLSDA
                     VTSIGTSIAIFAAAFNFPIVDKIAAIIITFFILKTAYDIFMESFFTLSDGFDENLLKK
                     YEEDILKLPKIVSVKSQRGRTYGANIYLDVVLEMNPDLSVYESHEVTEQVEQLLTLKH
                     GVFDVDIHVEPSEIPHDEMYEHVYDKLFRFETEIQAHANGYEELIDDQYLLIDAKGRY
                     RNKTQMLADHPIQTTYLSNYQMTSISQKSKLVTFEIGDYVHTSLWRRHENWTVIFHQI
                     SKKQASQIEATEKSSDLHNP"
BASE COUNT         1960 a         1444 c         1145 g         1810 t
ORIGIN      
        1 tcctctatct tgatagaatt tctggtctta gccatcgtgg aaaagcagga ttcctacggc
       61 tatgaaatca gtcaaaccat caagatagtt gctgatataa aggaatccac actctaccct
      121 attttgaaaa aattggaaaa ggcgggctac gtcaccacct atacccaaga atttcaaggg
      181 agaaagagaa aatactacac catcacacct gctggacgtg agcacatccc cttcctgcaa
      241 ggtgaatgga atagctacaa agaccatatt gacggaatta tagaagggag cttacgaaaa
      301 tgacacgcgc agattatttg aaccaactgg aacaagcatt atttcaactt catccaagtg
      361 ccagacagga ggctttagac tacttcaatg aatattttga cgaaaaggat aacgacgagg
      421 aagctattat agagctagga acacctgatg aagcagcaaa ggaaatcatt gccaatctac
      481 ctgaagatgc cctaatcacc gagcaagacc aagcaagtcc acattcatct aaaccatttg
      541 atttcaactt tgattttgat tttcaatttg actgggagaa ttttttcaac aattttaaac
      601 attcagccta tcaagctagg gaaagaatta aattgacggc gaagattgaa gaattacctg
      661 agttttcaaa tctacagatt tcgctcgaag atcaggctct tagcgttcaa agttataacg
      721 gagaagctgt cttattgcac aatcctgttt cagaagatgg tagctaccag gcttttgact
      781 atcaactggt tcaggatagt ttgtacctaa caagcaagcc tacccctaat cacctctact
      841 tctcaaacaa tcaaaccagc tctgctattc tcaaaatccc taaaaaacta ctgcccctta
      901 ctagtctcaa tctgaaaacg acagatagta gtctgacgat ggcggctgtg caagcgagcg
      961 aacagctagt catcaatgca aaagatagca gtatcagcat gacgaaagtg agctgcccaa
     1021 gctctgctct acggttagaa gactctacac taactatctc agatggacag atgagcgagt
     1081 taaaattgga agccagcgat gctgttatca ctctctcaag catgagcctt tcagatgcaa
     1141 ggataacatt agaagactgt gtctggaagt tgaaggattt tgttattgaa aagagcctta
     1201 actgccaggc tgaagattct gtcttaacct ataaaccaag tacggacatc agtttagaca
     1261 tctgggagga agattctagc cttaaacttc caaaggataa ggcgtttaca atgatgaaag
     1321 agggtgacat cactcatctc agctacaagc aagaaaatag ccctgctcag ctagttattc
     1381 attgtcaaga ctgccagctt agtgtgggat aaaggaggtt tccatgaatc gcaaggaata
     1441 tttacagaaa ctcgaaaaat atctcaaaaa cctaccaaaa gaagattttc aagatacctt
     1501 ggactatttc aatgaatatt ttgacgaaaa ggaaaacgat gagcaagcta ttcaagagct
     1561 aggcagtcca aaagaagccg cccatgaaat cctagccaat ctctatgata aagagaagac
     1621 tgaggataag ccaaataccc gcaatatggt ctggctgacc atcctctcta tccttgccgc
     1681 cccaatcggc gtccccctag caatcacctt ggtcgccctc ttcatcaccc ttctcctaat
     1741 catctttagc ctctttctgc tccttatctc actctggatt gtcctcctca gtctagcaat
     1801 cgcccagcta ctcctcgcct ttgacctctt cacactatca tggtctacct ccctcctctt
     1861 cacaggcctg gccctcatct gcttggccct cactctattg ggtagtaaat tcactctaga
     1921 ccttggaagc aaaaccttct tgcttgtttt acattggata caaagaaaga ttcgcaaagg
     1981 aggctattat gaaacagctt aaaccattta cgaaaatcag tctgagcctg ttcactcttg
     2041 gaacaattct cagtctcatt ggctacctgg ctggcggttg gacaaatatg aaaactgttg
     2101 cagaaaacta ttttcagccc caaacggcaa gctttacgga tattcgttct atagaggtca
     2161 atgaaaaact gtccattatg ccctcgcctg acaaacaatt tcacctccac tattaccgaa
     2221 atcagcacaa aggcattgac ctcctcagcc accaagttca agatggaaaa ttaaccattt
     2281 ctagtgccta tcaaggcatc gttacttatg atggtttact cgaacctatc ttaaatcttg
     2341 tcaatgacca gaatgttgcc tactaccaac ctgtcttaca ggtccctaaa aatagcacaa
     2401 tcgaaacact ctcagggagc attcaaggag atgtctatct ggataaagtg actattcaag
     2461 atttccaact ctttgttgaa aatggtgaca tgttgattga aaacagtcaa ctcagctttg
     2521 ctcatttgtc acacctcaat ggagaagtag caatcaatca ttccacatta ataagtccga
     2581 aagacatttc cgatactgtc ggcagtagct taacgattga ggatggggat tttaaagctg
     2641 aaaacctaaa actagaagga agacatagta tcagtaatta cggtggttca atcgacattt
     2701 ctcttcattc caaaacaaaa actgacatcc atatagatgc cagtcaaaat aatctgggaa
     2761 ttgaccttcc aacctattcc aatccccaat ccactaatta cctcaacatc tctacactag
     2821 atggtgaatt gagcattcgg taatcgctaa aaagccctcc tcacggaagg cttttctatt
     2881 tatttaaaca acaaaataga gatcaatgcc aagatagctg gtccaccttg ggttaagata
     2941 atttttggac ttgctgtaat agcaccataa gctgctgcag caataacaca tagaacaaaa
     3001 atgcttgtaa tttctaaatt accagtaaaa ataccgtaga acaagaagac cgccaacaag
     3061 ccattataaa ttccttgatt cttgaacaat gcagtcacag acttacgttg taattcttcc
     3121 ttctccatat tgaatacgcg actagtagag tctgaatggg tcgcaaaggt ttccaaatac
     3181 atgatatata ggtgctcaat agctacgata ctagctagaa tagtggtaaa aatagacata
     3241 atgtctcctc tcaaaaaatt atataggtag attttgcaag ccaatcaata gtttatcaag
     3301 agtggctagg aattgctcgc tctcctcaac agttagaatc tgattcatcg aagctttgat
     3361 agcttggtgg tgggcagaag gattcgtgat tagcgcttct ctagcctgct cagttggcca
     3421 gacaagtact tctctctgat tgtcaggatt tcgcttgcga atgatatagc cactctcctc
     3481 caacaatttg agatgacgcg taaccgctgc gcggtctatc tgaagccgct cctgcaaagc
     3541 caactgatgc aggggtgcat cttttagtaa tgtttgcaat attgaatagc gtgtcaaact
     3601 gattcccaac tgcttttcaa aaagattgga aatcgtctca tctgtcactt tcaatctgta
     3661 taacaaatct tccatttctt gcattatcta cctcttttga ttgattaatc aatcattgat
     3721 gagtcaatta tactacaatc cgaacaattt tcaactattt tgcctatcta ttaaaaaaat
     3781 atgttgccta cacctatatt ttgttataat taaggaaata actagcagag ggatgggact
     3841 tacttatgga aaacactcct agactaaact tggtcataga cgtgctcatg ctcgctggtg
     3901 ccattttggc acaaagcggt gcagaaattc accgagttga agataccatg attcggattg
     3961 cacattcaca aggaattgaa caggccaatg tccttgccat ccctgctgct atctttttct
     4021 ccatcgacca tacgaatatt tcgcgtatga aacgcattgt caattcaaat tacgacatgc
     4081 agaaagtttg tgacgtcaac caaatctccc gttccctagc caatgaagaa atcagcctag
     4141 aagaagcatg gagccaatta aatgcaatca aacaacaaaa gccaccttat aacaatatcc
     4201 aaataacctt agctgccgta gtagccgcac cattttttac catcatgttc ggaggttctc
     4261 ttttagatgc agcaggtgct gtcctcgcaa cagctttagc tttccctatc tccctaattg
     4321 tcgagcgcta tattggaatt gattttgtca ccaccttcgt tggcgccttt gtcttctcac
     4381 tcacctctta tttattaagc gcaaccacta ctctccccat taatcctaac ctgattaatg
     4441 caggggcagt catgcctttt gtaccaggga ttgcttttac aaatgccgta agagacctca
     4501 tgaccaatca tatcaataca gggatgacca aatttttcca aactgcgctt attatcttat
     4561 cgctcggtgc aggtacaact gtggccttta tgcttgtgag gtaatctatg acaccagttc
     4621 acttcttatt acaggcactc gcctcttata tcgctatcgc agccttctta attgttctca
     4681 atgttcaaag aaaaatgctg gtccctggtg gactcctagg catgcttgtt tggctcatct
     4741 atctttcatt attaggacca actaatgtac tgattgctac ctttttcgca gcaattatcg
     4801 gatcctgtgt cagtcaaatc atgagtattt ggttaaaaac accctccgtc atcttttcat
     4861 tggctatact tgcaccactt gttccaggct atcgagccta catgaccacg acttatttcg
     4921 tttctgggga ccacgctcaa gccctaacca atatcactac cgtcttaact ttagccttag
     4981 tcattcccat cggtatggcc agcggaacaa tattattaca cctttataag gttcttcgaa
     5041 caggcaaaaa agcagcctaa ccccttgaaa ataaggggcc tttttgttaa aatgaaaact
     5101 tatcaaagga gatgctatga accaaaacgt aaccaatcta aaacttgctg aacgtggtgc
     5161 cttgctatct atcggtgcct atattgtctt atcaggtatc aaactcgttg caggacagct
     5221 ctttcattcg gatgccttac gagcagatgc cttcaataat atttctgata ttatcggtaa
     5281 tatcgctgta cttgttggac taaaaatggc acagaaacca gctgataccg atcataaatt
     5341 tggacactgg aaaatggaag acttggcaag cttgattaca tccttcatca tgtttgtcgt
     5401 tggtttccaa gtactctatg ataccctcca aaaactaatc agcaattctt ctatcgaagt
     5461 agacattatg ggggccattg tcggaatttt ttctgcacta gttatgttag ctgtttattt
     5521 atataataac cgcttggcaa aaaaagtacg ttccaaggcc ttagaagcag ctgccaagga
     5581 taatctatcc gatgcagtca cttccatagg aacttctatc gcgatctttg ctgcggcttt
     5641 caacttccct attgtcgata aaattgcagc catcatcatt accttcttta tcctaaaaac
     5701 agcctacgat atttttatgg aaagcttctt taccctatct gatggatttg atgaaaactt
     5761 attgaaaaag tacgaggaag atattctcaa actcccaaaa atcgtttctg tcaaatcaca
     5821 acgtggtcgg acttatggag ccaatatcta ccttgatgtt gttttagaaa tgaatccaga
     5881 cttatccgtt tatgaaagtc atgaagtgac tgagcaggtt gagcaactcc taacactcaa
     5941 acatggagtt tttgatgtgg atattcacgt agaaccatct gaaattccac acgatgagat
     6001 gtatgagcat gtgtacgaca aactcttccg ttttgaaaca gagatacaag cacatgctaa
     6061 tgggtatgaa gaattgattg acgaccagta tctcttaatt gatgccaaag gccgctatcg
     6121 aaataaaact cagatgcttg ccgaccaccc catccaaacc acgtatttat ccaattacca
     6181 aatgacctcc attagccaaa aatcaaaatt agttacgttt gaaattggtg attatgttca
     6241 tacgtcactt tggcgccgtc atgaaaattg gactgttatt ttccaccaga tttcaaagaa
     6301 acaagcctct cagatcgaag ctactgaaaa aagctctgat ttgcataatc cataataaa
//
LOCUS       DBNFCO010000090         6158 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.090, whole genome shotgun sequence.
ACCESSION   DBNFCO010000090 DBNFCO010000000
VERSION     DBNFCO010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6158)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6158)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6158
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.090"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            25..642
                     /locus_tag="AC1PIV_001713"
     CDS             25..642
                     /locus_tag="AC1PIV_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDSL-type esterase/lipase family protein"
                     /protein_id="HIP6612717.1"
                     /translation="MSDIMYPEVLTVGSGAVKVATVGDSLTYGYGLENREKDAYPCIL
                     AEKLGHHYQVSNYGLSGRSLQSTADFPYFKEKNAQLSLESEADIVIIMIGSNDSRGPY
                     WNRERFIQEYREMAEQYMDLPSQPDVYLVIPPYVPTSRFGLNNQIIEDELQKIIPAIG
                     NELGLPVINLYTVTEGHLEYYSDGLHLTPLGNQVIAEEIYQHLRH"
     gene            685..1227
                     /gene="lepB"
                     /locus_tag="AC1PIV_001714"
     CDS             685..1227
                     /gene="lepB"
                     /locus_tag="AC1PIV_001714"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HIP6612718.1"
                     /translation="MVKRDLIKQISLLVLLIFGIIGLRFWLLEPVTITPEMANSYLKE
                     NDFIMTVRNVRPIHGDFILYNHEGKEYVSRVIALENETVTYMDDVLYRNDIIVTENYL
                     KTPHSQESYTDDFTLETLTNGKYNIIPEGHYLVLNDVRTNQQDSRSFGLISSEAIVGR
                     LTFRISPLSEFGFIKTGLVQ"
     gene            1417..3228
                     /gene="glmS"
                     /locus_tag="AC1PIV_001715"
     CDS             1417..3228
                     /gene="glmS"
                     /locus_tag="AC1PIV_001715"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HIP6612719.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVTGGEQAHL
                     VKAVGRIAELSAKVGDKTEGTTGIGHTRWATHGKPTENNAHPHTSQTAGHILVHNGVI
                     ENYAEIKEEYLAGHDLKGQTDTEIAVHLIGQFAEEGLSTLEAFKKALKIIQGSYAFAL
                     IDAADADTIYVAKNKSPLLIGLGDGYNMVCSDAMAMIRETSEYMEIHDKELVIVKKDS
                     VEVMDYDGNAIERGSYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLISAYTNEAGQ
                     VTVDADIIKAVQEADRIYILAAGTSYHAGFAAKDFLEKLTDTPVELGISSEWGYSMPL
                     LSKKPLFVMISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREATYTMLLHAGP
                     EIAVASTKAYTAQIATLAILAKAVGDANGNAYAKEFDLVHELSIVAQSIEASLSEKDV
                     IAEKVEKLLSTTRNAFYIGRGSDYYVSMEASLKLKEISYIQCEGFAAGELKHGTISLI
                     EDGVPVLALISNHPHLASHTRGNIQEVVARGANVLTIVDEAVAKEEDDITVTTVHPFL
                     SAIAMVVPTQLIAYYATLQRGLDVDKPRNLAKSVTVE"
     gene            3380..4021
                     /locus_tag="AC1PIV_001716"
     CDS             3380..4021
                     /locus_tag="AC1PIV_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004228788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HIP6612720.1"
                     /translation="MDYVLEVLPSLLNGAAVSLQVFFLVLILSLPLGAVFAFLMQIKF
                     KPLQWLLHFYVLIMRGTPLLLQLIFVYYVLPSVGITFDRMPAVILAFTLNYAAYFSEI
                     FRGGIEAIPKGQYEAAKVLKFTPVQTIRYIVLPQVVKIVLPSVFNEVMTLVKDTSLVY
                     ALGVSDLLLASRTAANRDASLAPMFIAGAIYLLMIGAVTLISKQVEKKFDYYR"
     gene            4031..4663
                     /locus_tag="AC1PIV_001717"
     CDS             4031..4663
                     /locus_tag="AC1PIV_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009909533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015424 - ABC-type amino acid transporter
                     activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HIP6612721.1"
                     /translation="MLELRNLSKRFEDKQIFSNYDLVIPEGKIVAIVGQSGGGKTTLL
                     RMLAGLETIDSGTLMYNGQELPLEELGKRHLLGFVFQDFQLFPHLSVLENLVLSPMKT
                     QNMLRSEAEDKALKLLDTLGLANHANAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRKEVEKLILENRATGITQIVVTHDMQFAENIADEIIKIEPKH"
     gene            4690..5520
                     /locus_tag="AC1PIV_001718"
     CDS             4690..5520
                     /locus_tag="AC1PIV_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HIP6612722.1"
                     /translation="MKKMMLGALALVTSLTLAACGSNDSATKSDNWTAYESEKSVTIG
                     FDKTFVPMGFEQTDGSYTGFDIDLANAVFEKYGITVKWQPIDWDLKETELNNGNIDLI
                     WNGYSITDERKEKVLFTNPYMDNQQVLVTKKSSNISQVSDMKDKILGAQAGSSGYSVF
                     ESQPAILKDIVQNNDASQYATFNEALIDLKNDRIDGLLIDRVYANYYLQQEGIIADYN
                     IIDAGFENEAFAVGARKSDTTLVENINKAFAELYKEGKFQEISQKWFGEDVATDTVKK
                     "
     gene            complement(5978..>6158)
                     /locus_tag="AC1PIV_001719"
     CDS             complement(5978..>6158)
                     /locus_tag="AC1PIV_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HIP6612723.1"
                     /translation="KGSPLAERYYQIQSRRGSQKATIALAHQLLKIAYILLKEQMTYP
                     EFLAQKKTTRDELVA"
BASE COUNT         1870 a         1050 c         1360 g         1878 t
ORIGIN      
        1 aataagaaaa attgaggagt tcgtgtgtca gatataatgt atcctgaggt cctaactgtt
       61 ggaagtgggg ccgtaaaagt tgcaacagtc ggagatagtt tgacttatgg atatggcttg
      121 gagaatcggg aaaaagatgc ctatccttgt attctagctg agaaacttgg gcatcactat
      181 caagtttcaa attatggatt gagtgggcgt tcacttcagt caactgcaga ttttccttac
      241 tttaaagaga agaatgccca actttcactt gagagtgaag cagatattgt catcatcatg
      301 attggtagta acgatagccg aggaccatat tggaataggg agaggtttat tcaagagtat
      361 agggaaatgg cagagcagta tatggattta ccaagccagc cggatgttta tttagtcatc
      421 ccgccttacg taccaaccag tcgttttgga ttgaataatc aaattattga agatgaatta
      481 caaaaaatta tcccagctat cggaaacgaa cttggtttac cagttattaa cctttacact
      541 gtgacggagg gacatcttga atactatagc gatggtcttc atttgacacc gttaggaaat
      601 caagttattg ctgaagagat ttaccagcat ctcagacact aatggctcta aattgtggta
      661 taatactagt gaaatggaga gattatggta aaaagagatt taataaaaca aatcagttta
      721 ttggtcttat tgatttttgg aatcattggc ctacgatttt ggttacttga gccagtcacg
      781 attacccctg agatggcaaa tagttatttg aaggaaaatg actttatcat gacagtgcga
      841 aatgtccgcc cgattcatgg agattttatt ttgtataacc atgagggaaa agagtatgtg
      901 agtcgtgtga ttgcattgga aaacgagacg gttacctata tggacgatgt tctctatcgt
      961 aatgatatta ttgttacaga gaactattta aaaacgcctc attcacaaga aagttataca
     1021 gatgacttta cattggaaac cttgacaaat ggaaagtaca acatcattcc agagggacac
     1081 tatttggtgt tgaatgatgt acgaacgaat caacaggata gtcgtagttt tggtttgatt
     1141 tctagtgagg ctattgttgg tagactgact tttcggatta gtccactttc agaatttggt
     1201 tttattaaga cagggctggt tcagtagaat cagctttttt tattgtattg agatggctgg
     1261 aactgtattt tgaaattaga ctagaccaat taaaatgttg acaaggatga aatcttgtta
     1321 tatactgatt tcactggtct ttttagatat aaattagact agaccaattt ttaaagaaat
     1381 gaaagccgat gttaacaaac atcgtaggtg atatgtatgt gtggaatcgt tggtgttgta
     1441 ggaaatacaa acgcaactga tattttgatt caaggacttg aaaaattaga ataccgtggt
     1501 tatgattcag caggtatttt tgtgacgggt ggtgagcaag ctcatcttgt gaaagctgtt
     1561 ggtcgcattg cagaattgtc tgcaaaagtt ggcgataaga ctgaagggac aacagggatc
     1621 ggtcatactc gttgggcgac tcatggtaag ccaactgaga acaatgctca ccctcacact
     1681 tctcaaactg ctggacatat cctagttcac aacggtgtga ttgaaaacta cgcagaaatc
     1741 aaggaagagt atcttgcagg tcatgacttg aaagggcaga cagatacaga aattgctgta
     1801 cacttgattg gtcaatttgc agaagaaggt ttgtcaactc tagaagcctt taaaaaagca
     1861 ttgaagatta ttcaaggttc atatgccttt gctttgattg atgctgcgga tgcagataca
     1921 atctatgttg ccaaaaataa atctccactt ttgattggtc ttggtgatgg ctataacatg
     1981 gtctgctcag atgccatggc tatgattcgt gagacaagtg aatacatgga aattcacgat
     2041 aaggaattgg ttatcgtgaa aaaagatagt gttgaagtca tggactatga tggcaatgcg
     2101 attgaacgtg gtagttatac agctgagctt gatttgtcag atattggtaa gggaacttat
     2161 ccatactaca tgctcaagga aattgatgag cagccaactg ttatgcgtaa attgattagt
     2221 gcctatacaa atgaagctgg tcaggtaaca gttgacgcgg atattattaa ggcagtacaa
     2281 gaagctgacc gtatctatat cttggctgct ggaacttcct atcacgcagg atttgccgca
     2341 aaagacttct tggaaaaatt gacagataca ccagtagagt tgggaatttc atctgagtgg
     2401 ggctacagta tgccactttt gagcaaaaag ccactctttg tcatgattag ccagtcaggt
     2461 gaaactgctg atagccgtca ggtattggtt aaagctaatg aaatgggcat tccaagtttg
     2521 actgtaacca acgttcctgg ttcgacccta tcacgtgagg caacttacac catgttgctc
     2581 catgcaggac cagaaattgc ggtagcttct acaaaagcct acactgcaca gattgcgact
     2641 ttggcaatct tggcgaaggc tgtcggtgat gcaaatggca atgcctacgc gaaagaattt
     2701 gacttggtgc atgaattgtc catcgtagct caatctattg aggccagctt gtcagaaaaa
     2761 gatgtgattg ctgaaaaagt tgaaaaactc ttatcaacca ctcgcaacgc attctatatc
     2821 ggtcgtggta gtgactacta cgtttctatg gaagccagct tgaaattgaa agaaatttca
     2881 tacatccaat gtgaaggctt tgcggcaggt gaattgaaac acggtaccat ttcattgatt
     2941 gaagacggtg ttcctgtctt ggccttgatt tcaaatcatc cacatcttgc aagccatact
     3001 cgaggcaata ttcaggaagt ggtggcgcgt ggtgccaatg tcttgacaat tgtagatgaa
     3061 gcagtagcta aggaagagga tgacatcact gttacaacgg ttcatccatt cttatcagcg
     3121 attgctatgg ttgttccgac acagttgatc gcttactatg cgacattgca acgcggtttg
     3181 gatgttgata aaccacgtaa cttggctaag tctgttactg ttgaataaga agataaggtt
     3241 cggatttcgg accttttttt caaatcaatg aaaaaacata caaaattttg ttaaatttat
     3301 taaaaattct gaaaaattct ttgaaattaa ggatattttt tgatatacta gaacctaata
     3361 attcttttag gagagctcta tggattatgt tttggaagtt ctgcccagtc tactaaatgg
     3421 tgctgcagtc tccttgcaag tattttttct agtattgata ttatccttgc cattaggagc
     3481 tgttttcgct tttttaatgc agattaaatt taaaccctta caatggttat tgcatttcta
     3541 tgtattaatt atgcgaggaa cccccttact tttacaatta atttttgttt attacgtctt
     3601 accaagtgtg ggtattacat ttgaccgaat gcctgctgtg attctggcct ttacgctcaa
     3661 ctatgcggcc tatttctctg aaattttccg tggtggtatt gaagctattc caaaaggtca
     3721 gtatgaagct gctaaggtat tgaaatttac ccctgttcag accattcgct acattgtctt
     3781 accacaggtt gtgaaaattg ttctgccaag tgttttcaat gaagtcatga ctttggtaaa
     3841 ggatacttct ttggtctatg cacttggggt tagcgatttg ttgttggcta gtcgtactgc
     3901 ggccaatcgt gatgccagct tggcacctat gtttatcgca ggtgcaatct acctattgat
     3961 gatcggtgcg gtaacactga tttctaaaca agtagaaaag aaatttgatt attatagata
     4021 ggaggaagtc atgttagagt tacgcaattt gtcaaaacgc tttgaagata aacagatttt
     4081 ctccaactat gatttggtca ttccagaagg gaaaattgtt gccattgttg gtcaatctgg
     4141 cggtggtaag acaactcttt tacggatgtt ggctggttta gagactattg attcaggaac
     4201 tttgatgtat aacggtcaag aactgccatt agaggagttg ggaaaacgac atttgctggg
     4261 ctttgtcttc caggacttcc agcttttccc gcacctatcc gtattggaaa acttggttct
     4321 ctctcctatg aaaacgcaaa atatgttgcg ttcagaggcg gaagacaagg cccttaaact
     4381 cttggatact cttggacttg ctaaccacgc aaatgcctac ccattttcat tatcgggtgg
     4441 acagaaacaa cgtgtggcct tggcgcgtgc gatgatgatt gatcctgaga ttatcggcta
     4501 tgatgaacca acttcggccc tagaccctga attaagaaaa gaagttgaga aactgattct
     4561 tgaaaatagg gctactggaa tcacgcaaat tgtggtcacc catgatatgc agtttgctga
     4621 gaatatcgca gatgaaatca tcaaaattga accgaaacac taagaaaagg aacaaatatg
     4681 atgatgaata ttaaaaaaat gatgcttgga gctcttgctc ttgtaacttc tttgactctt
     4741 gctgcttgtg gctccaatga ttcggctact aagtctgata attggacagc ctacgagtct
     4801 gaaaaatccg ttacgattgg ctttgataag acctttgtcc caatgggatt tgaacagaca
     4861 gatggttctt acacaggttt tgatattgac ttggctaatg cagtctttga aaaatatgga
     4921 attactgtaa aatggcaacc aattgactgg gacttgaaag aaactgaatt gaataacggg
     4981 aatattgatt taatttggaa tggttattct attacagatg agcgtaagga aaaagttctt
     5041 ttcacaaatc cctacatgga taaccaacaa gttcttgtaa ccaaaaaatc ttccaatatt
     5101 agccaagtat ctgatatgaa ggataagatt ttaggtgcgc aagcaggttc atctggctat
     5161 tcagtatttg aatcacaacc agctattttg aaagatattg ttcaaaataa cgatgcaagt
     5221 cagtatgcga ccttcaatga agccttgatt gacttgaaaa acgatcgtat tgatggcctt
     5281 ttgattgacc gtgtgtatgc aaattattac ttgcaacaag agggaattat cgcagattac
     5341 aacatcattg atgcaggttt tgaaaatgaa gccttcgcag tcggtgctcg taaatcagat
     5401 acgacactcg tggaaaacat taataaggcg tttgctgaat tatataaaga aggtaaattc
     5461 caagaaatct cccaaaaatg gtttggtgag gatgttgcaa ccgacacagt aaaaaaataa
     5521 taatgtaagc aaaagtgact gaacaagaca tccatgatgg ttacaccctc atccacagaa
     5581 taatgaaaag aactcgtgaa aacggtgggg tgtacaccaa tatcattaac ttaagattct
     5641 acgaggctga gcaaaaagct cagcgccact tctcggagtt cgtgtcaaca tctcagcgca
     5701 gtggttgatt ggcttaaaca gtcactattc tgactgttgg agctatgcgg gggtgggagt
     5761 ttaaaaggtc tgggagacct tttaaagtgg gagatataag ctgacggcag tcagctcaca
     5821 taaattgatg tctggggata gattgtttca gctcaacaac ttaaaacgaa aaattgttga
     5881 cgaacttttt ttcgtctggt cgagttctta tacgaaaact caaaagaatg caaaaattcc
     5941 cttcctatga tataatcaaa gtgaaaaaaa tttgtattta ggctactagt tcgtccctag
     6001 tagtcttttt ttgtgctaaa aattcaggat aagtcatctg ttcttttaaa aggatatagg
     6061 ctatttttaa tagttgatgc gcaagtgcaa tggttgcttt ttgtgagcca cgccgacttt
     6121 gaatctgata atatcgttct gctaatgggc tgcctttt
//
LOCUS       DBNFCO010000091         5874 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.091, whole genome shotgun sequence.
ACCESSION   DBNFCO010000091 DBNFCO010000000
VERSION     DBNFCO010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5874)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5874)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5874
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.091"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(82..1587)
                     /gene="pyk"
                     /locus_tag="AC1PIV_001720"
     CDS             complement(82..1587)
                     /gene="pyk"
                     /locus_tag="AC1PIV_001720"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HIP6612724.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGDDGYWGEKLDVESSAQKIAA
                     LITEGANVFRFNFSHGDHQEQGDRMATVRRAEEIAGKKVGFLLDTKGPEIRTELFEDD
                     AKEYAYTTGDKLRVATKQGIKSTKEVIALNVAGGLDVFDDVEVGKQILVDDGKLGLTV
                     VEKDAVNREFVVLVENDGVIAKQKGVNIPYTKIPFPALAERDNADIRFGLEQGLNFIA
                     ISFVRTAKDVEVVRNICKETGNDHVQLFAKIENQQGIDNIDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIITKVNAAGKAVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPVESVRTMATIAKNAQTLLNEYGRLNSDQFNRASKTEVIASAVK
                     DACHSMDIKLVVTVTETGYSARSISKYRPDADILAVTFTEKVQKSLMLNWGVIPIVTN
                     RPDSTDDMFDLAERIAKEQGLVEAGDDIIIVAGVPVGVAGSTNTMRVRTVK"
     gene            complement(1654..2664)
                     /gene="pfkA"
                     /locus_tag="AC1PIV_001721"
     CDS             complement(1654..2664)
                     /gene="pfkA"
                     /locus_tag="AC1PIV_001721"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HIP6612725.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVYGINEGYAGM
                     VAGDIHELSARSVGDIISRGGTFLCSARYPEFAKLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGVPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVVEVMGRHAGDIALWAGIASGADVIVVPEEDFNINDVVDRIKAGYDKGKKHSII
                     VLAEGVMPAAQFAEELKAAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGRGGLAVGIRNEQMVENPILGTAEEGALFSLTTDGKIVVNNPHKADLELADLNRNL
                     SI"
     gene            complement(2749..5859)
                     /locus_tag="AC1PIV_001722"
     CDS             complement(2749..5859)
                     /locus_tag="AC1PIV_001722"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002940960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HIP6612726.1"
                     /translation="MLAQLDTKTVYTFMDSMVTIESYVGRAKELGYHALGIMDKNSLY
                     AAYSFMESCNKMGLQPIIGCELDWKLQGEEQDITTQLIALTTRGYRNLLKISTAKMTG
                     QDDFETIRQYLVDIAVVVPYFSGIEHLELGVNYYIGVTVDTPVQDFKQAPLPIHTVRF
                     FEEEQLESLQVLHAIRDNIPLNQVSDVDSRQKLLSADSLTNLFSNRFPQAVDNLRDLV
                     AGISYQLNTDLKLPRFNRDRPAVEELYERSYQGLEEKGLTNSLYKERLEKELSIIHQM
                     EFDDYFLIVWDLLRFGRSQGYYMGMGRGSAVGSLVAYALNITGIDPVKHNLLFERFLN
                     AERYSMPDIDIDIPDIHRADFIRYVRDRYGSTHAAQIVTYSTFGAKQAIRDVFKRFGT
                     PEYELSNITKKISFRDSLTSAYQRNAAFRQIINSKIEYQKAFAIAQQIEGQPRQTSIH
                     AAGIVMSDEELTDTIPLKIGDDMLVTQYDAHAVEANGLLKMDFLGLRNLTFVQKMAEG
                     VRERYQQEIDIAKIDLEDKKTLELFAAGRTKGIFQFEQPGAISLLRRVKPGRFEDIVA
                     TTSLNRPGASDYSDNFVKRKHGQETVDLLDPTIAPILQPTYGIMLYQEQVMQIAQVYA
                     GFTLGKADLLRRAMSKKNAQEMQAMEAEFLQGALKNGHAEENAREIFGMMAKFAGYGF
                     NRSHAYAYSALAFQMAYFKSHYTDVFFDVMLNHSSSAYIEDAMQFDFEVARLTINNIP
                     YHDKFDKSKVYLGLKTLKGLPKDLALWILDHRPYKSVEDFILRLPDNFKKKDLLIPLI
                     QIGLFDDFDANRKKIIENLDNLFVFAEAIGTFFAEESYSWTDVEDYSDSEKFMLEQEL
                     LGVGISPHPLVNICRESKRSFTDLADLAVGNRATVLVQIQAIRLIRTKKTGEQMAFLR
                     VTDTKRTLDVTLFPESYRQYASILEEGGMGYITGRVQERDGQLQLVLEKLEPVSLEKF
                     WILLENREHDYAVARILDKYRGSIPVVLHYQDSNQTIQAEHHMVMKTPQLEEELSEFV
                     MKTIFR"
BASE COUNT         1731 a         1363 c         1004 g         1776 t
ORIGIN      
        1 atttagaggc aaaaaatcta taacagcacg tatttaactt attctctaat tactacaaaa
       61 aggtccaagc ggaccttttt attattttac tgtacgaaca cgcatagtat ttgttgaacc
      121 tgcaacacct acaggcacac cagcaacgat aataatgtca tctcctgctt caacaagacc
      181 ttgctctttg gcaatacgtt cagccaaatc aaacatatcg tcagttgaat ctggacggtt
      241 tgttacaatt ggaataacac cccagttaag catcaatgat ttttgtactt tctcagtaaa
      301 tgttactgcc aagatgtccg catctggacg gtatttagag atcgaacgag ctgagtaacc
      361 tgtttctgta actgttacaa ctagtttgat gtccattgag tgacatgcgt cttttactgc
      421 agaagcaata acttctgttt tagaggcacg attaaactga tcagagttca aacgaccata
      481 ttcattaaga agagtctgtg cgtttttagc gatagttgcc attgtacgaa ctgattctac
      541 tggatattta ccgtttgcag actcgcctga aagcattgtt gcatcagtac cgtcgataac
      601 agcattgaat acgtcagata cttcagaacg agttgcacgt ggtttttcag tcattgtttc
      661 caacatgttt gttgctgtga taactgcttt accagctgca ttcactttag tgataatcat
      721 tttttggtaa actggaacca tttcgaatgg tacttcgata cccatgtcac cacgagcaat
      781 catgatacca tctgctgctt cgatgatttc gtcgatgttg tcgatacctt gttggttttc
      841 gattttcgca aacaattgaa cgtggtcgtt accagtttct ttacagatat tacgaacaac
      901 ttctacgtct tttgcagtac gtacaaatga gatagcaata aagttcaaac cttgctcaag
      961 accgaagcgg atatctgcat tatcacgctc tgcaagagct gggaaaggaa tttttgtgta
     1021 agggatgttt acaccttttt gtttagcaat tacaccgtcg ttttcaacca aaacaacaaa
     1081 ttcacggttt actgcatctt tttcaacaac tgtcaaacca agtttaccat cgtcaacaag
     1141 gatttgctta ccaacttcaa catcgtcaaa gacatccaaa ccacctgcta cgttcaaagc
     1201 aatcacttct tttgtagatt tgataccttg ttttgtagca acacgcaatt tgtcaccagt
     1261 tgtatatgcg tattcttttg catcatcttc aaacaattct gtacggattt ctggaccttt
     1321 tgtatccaac aagaaaccta cttttttacc agcgatttct tctgcacgac gaactgttgc
     1381 catacgatca ccttgctctt ggtggtcacc gtgtgagaag ttgaaacgga aaacattggc
     1441 accttctgta atcaaagcag cgattttctg tgctgatgac tcaacatcta atttttcacc
     1501 ccagtaacca tcgtcaccga attttttacc accgcggatt tctaccgctg gaccaagggt
     1561 tgcaacaatt ttaacacgtt tgttcatctt aacaaaactc cttttatttc aatggtcata
     1621 tgacccttaa ttaacacttt taaacaatga tacctagatt gacaagttac ggttcaaatc
     1681 agccaactcc aaatctgctt tatgcggatt attaactaca atcttgccat cagtagtcaa
     1741 gctaaacaag gcaccttctt ctgcagttcc aagaattgga ttttcaacca tttgctcgtt
     1801 acggatacct accgcaagac ctccacggcc ttctttaagc aatttaacgg catgagcacc
     1861 catacgagaa gcgagtacac gatcacgcgc tgttggagaa ccaccacgtt ggatatgacc
     1921 aagttctgtc acacgaagat cacttgtatc gcctgctgct ttcaattctt cagcaaactg
     1981 tgccgctggc ataacacctt cggccaagac aatgatgcta tgtttcttac ctttatcgta
     2041 gcccgcttta atgcgatcaa caacatcgtt gatattgaag tcttcttctg gaacaacgat
     2101 aacatctgca ccagaagcaa taccagccca aagagcgatg tctcccgcat gacgtcccat
     2161 tacttcaaca acgaaagtac gacggtgact tgatgaagta tcgcggattt tatcaatcgc
     2221 atccatagca gttgttacag ctgtatcaaa accgattgta aaatctgtac ccacgatgtc
     2281 gttatcaatt gtaccaggta caccaatagc tgggaaacca tgctccgtca agcgcattgc
     2341 accgtggtaa gaaccatcac caccgataac aactacacct tcgataccat gttttttcaa
     2401 ttgctcaatc cctttaagtt gcccttctaa tttggcaaat tctggataac gagctgaaca
     2461 aaggaatgtt cctccacgtg aaataatatc acctacagaa cgtgcagaca attcatggat
     2521 atcacccgca accatacctg cgtaaccttc gttgattcca taaacttcca ttccttctga
     2581 aattgcttgg cgaacaactg cacgaatagc agcgttcata ccaggggcat caccaccact
     2641 ggtcaaaaca gcaatacgtt tcattcgtta atgctccttt aacttttcat tttaactgcc
     2701 ctattataac atacttagcc taaacttgct tgactttttg ctattttttt atcgaaaaat
     2761 cgttttcata acaaattcac ttaactcttc ttctaattga ggcgttttca taaccatgtg
     2821 gtgctcagcc tgaattgtct gattactatc ttgataatga agtactactg gaatgcttcc
     2881 tctatattta tccaaaatac gagcaacagc ataatcgtgt tctcgatttt ccaaaagaat
     2941 ccaaaatttc tctaaactga caggctctaa tttttctaga actaattgca actgtccatc
     3001 ccgctcttgc actctacctg tgatgtaccc cattccccct tcttccaaaa tagaagcgta
     3061 ttggcgataa gattcgggga aaagagtcac gtcaagcgtc ctcttggtat ctgtcactcg
     3121 aagaaatgcc atctgctccc cagtcttttt ggtacgaatc aatcgaatag cttgaatctg
     3181 cacaagaacg gtcgctcgat tgccaaccgc taaatcagcc aaatctgtaa aactacgctt
     3241 agactctcga caaatattga ctaaaggatg cggactaata ccaacaccta gcaattcttg
     3301 ctctagcata aatttttcac tgtcgctgta atcttctaca tctgtccaac tataactctc
     3361 ctctgcaaaa aatgtaccaa ttgcctctgc aaagacaaag agattgtcta gattttcaat
     3421 aatctttttt cgattggcgt caaaatcatc aaataaacca atctgaataa gagggattag
     3481 taaatccttt ttcttgaaat tatctggcaa gcgcaaaata aaatcttcta cagacttata
     3541 gggacgatga tccaatatcc ataaagctaa atctttaggc aaacctttca gtgtttttaa
     3601 tcctaggtaa accttacttt tatcaaactt atcgtgataa ggaatattgt taatcgtgag
     3661 tcgagctacc tcaaagtcaa actgcatcgc atcttcaata taagcactgc tagaatgatt
     3721 gagcatgaca tcaaaaaaga catccgtata gtgactcttg aaataggcca tttgaaaggc
     3781 taaggctgaa taagcatagg cgtggctacg gttaaaacca taaccagcga acttagccat
     3841 catgccaaat atttcccttg cattctcttc agcatgtccg tttttcagtg ctccctgtaa
     3901 aaattccgct tccattgcct gcatttcctg cgcattcttt ttagacatcg ccctgcggag
     3961 taaatccgcc ttgccaagcg taaagcctgc atagacctgt gcaatctgca tgacctgttc
     4021 ctgataaagc atgataccat aagtcggttg taaaatagga gcaatggttg gatccaacaa
     4081 atcaactgtc tcttgtccat gtttgcgttt tacaaagtta tccgaataat cactagcccc
     4141 cggtctattc aaactcgttg ttgcaactat atcttcaaat cgaccaggtt tgacccttcg
     4201 aagcaggcta atcgcaccag gctgttcaaa ttgaaaaatt cccttagtcc gaccagcagc
     4261 aaaaagttcc aaggttttct tgtcttctaa atctatcttg gcaatatcaa tttcctgctg
     4321 ataacgttca cgtactcctt ctgccatttt ttgcacaaag gtcagatttc gtaagccaag
     4381 gaaatccatt ttcaacagac cattcgcctc aacagcatgt gcatcatatt gggttaccag
     4441 catgtcatcc cctattttaa gagggatggt atctgtcaac tcctcatcac tcatcactat
     4501 ccctgctgca tggatagaag tctgtcgggg ttgcccttca atttgttgag caatcgcaaa
     4561 agctttttgg tactctatct tactattgat aatctggcga aaagcggcat ttcgctgata
     4621 ggcagaagta agactatctc taaatgaaat tttcttggta atattactta actcatattc
     4681 aggtgttccg aaacgcttaa atacatcacg aatagcctgc ttagctccaa atgtcgagta
     4741 ggttacaatt tgagcagcat gggttgaacc ataacgatct cgtacataac gaataaaatc
     4801 tgctcgatga atatctggaa tatcaatatc aatatcgggc attgaataac gttcagcatt
     4861 gagaaagcgt tcaaagagaa gattatgctt aacaggatca atacctgtga tatttaaggc
     4921 gtaggcaact aggcttccaa cagctgaacc gcgccccatt cccatgtagt acccttggct
     4981 acgtccaaaa cgaagtaggt cccatacaat caagaaataa tcatcaaatt ccatttgatg
     5041 aataatggat aattcctttt ccaagcgttc cttatacagt gaattagtca agcccttctc
     5101 ttctaatcct tgataggagc gctcgtataa ttcttccact gcaggtctgt cacgattaaa
     5161 acgcggcaat tttaaatctg tatttaattg ataagaaatc cctgcaacca agtcacgtaa
     5221 attatcaact gcttgcggaa accgattaga aaatagattg gttaagctat cagccgataa
     5281 aagcttttgc cgactatcta catctgaaac ctgattaagc ggaatattat ctcgaatagc
     5341 atggagaacc tgtagacttt ccaattgttc ctcttcaaaa aaacgaacag tatggattgg
     5401 aaggggtgct tgcttaaaat cttgaaccgg tgtgtcaact gtcactccga tataatagtt
     5461 tacacccaac tcaaggtgct caatgccaga aaaataagga acaaccactg ctatgtcgac
     5521 taaatattga cgaatagttt caaaatcatc ttgccctgtc atcttagcag tcgaaatttt
     5581 caatagattg cgataacctc tggttgtcag agcaatcaat tgagtagtga tgtcctgctc
     5641 ctctccctgt aatttccagt ccagttcaca accaataatt ggttgaagcc ccattttgtt
     5701 acaggattcc ataaaactat aggctgcata aagactgttt ttatccatta tccccaatgc
     5761 gtggtaacca agctctttag ccctgcctac ataactctct atcgtcacca tgctatccat
     5821 aaaggtataa actgtctttg tatctaattg tgccagcatg gtattctcct tttc
//
LOCUS       DBNFCO010000092         5661 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.092, whole genome shotgun sequence.
ACCESSION   DBNFCO010000092 DBNFCO010000000
VERSION     DBNFCO010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5661
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.092"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(74..334)
                     /locus_tag="AC1PIV_001723"
                     /pseudo
     CDS             complement(74..334)
                     /locus_tag="AC1PIV_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
     gene            complement(504..1241)
                     /gene="erm(B)"
                     /locus_tag="AC1PIV_001724"
     CDS             complement(504..1241)
                     /gene="erm(B)"
                     /locus_tag="AC1PIV_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011100845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HIP6612727.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTITYEQVLSIFNSYLLFNGRK"
     gene            complement(1366..1449)
                     /locus_tag="AC1PIV_001725"
     CDS             complement(1366..1449)
                     /locus_tag="AC1PIV_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031556 - transcriptional attenuation by
                     ribosome [Evidence IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HIP6612728.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            complement(1516..2682)
                     /locus_tag="AC1PIV_001726"
                     /pseudo
     CDS             complement(1516..2682)
                     /locus_tag="AC1PIV_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167702.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative cross-wall-targeting lipoprotein signal
                     domain-containing proteiin"
     gene            2852..3442
                     /locus_tag="AC1PIV_001727"
     CDS             2852..3442
                     /locus_tag="AC1PIV_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HIP6612729.1"
                     /translation="MSKKEILLDFIEKNNGIVTNKDCKALGIPTIYLTRLEKEGIIFR
                     VEKGIFLTQNGDYDEYYFFQYRFPKAIFSYISALYLQQFTDEIPQYFDVTVPRGYRFN
                     TPPANLNIHFVSKEYSELGMTTVPTPLGNNVRVYDFERIICDFVIHREKIDSELFVKT
                     LQSYGNYPKKNLAKLYEYATKMNTLEKVKQTLEVLI"
     gene            3439..4284
                     /locus_tag="AC1PIV_001728"
     CDS             3439..4284
                     /locus_tag="AC1PIV_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HIP6612730.1"
                     /translation="MNKAKLTALCHKISKNTGLTFNSVMTYYFLEVILKKLSQSSYSN
                     HYIFKGGFLLSNVIGVESRSTVDIDFLFHQITLSEETVKQQLKEILADSEEGISFVIQ
                     SITAIKESDDYGGYRATISCQLENIKQVIHLDIATGDVVTPQPITYDYKAIFDEDNFP
                     IIAYTIETILAEKLQTIYSRNFLNSRSKDFYDVYILSKLKKEDIDFIQLRNACQRTFS
                     YRETELDFVKIIELLERFKSDPIQNKQWQNYSKKYSYTKGISLADVLDEMISLITIII
                     STDSD"
     gene            complement(4370..4654)
                     /locus_tag="AC1PIV_001729"
                     /pseudo
     CDS             complement(4370..4654)
                     /locus_tag="AC1PIV_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656693.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA];
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
     gene            complement(4768..>5661)
                     /locus_tag="AC1PIV_001730"
     CDS             complement(4768..>5661)
                     /locus_tag="AC1PIV_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Abi family protein"
                     /protein_id="HIP6612731.1"
                     /translation="TLLNMGYYHGYKRYRFVKKSNSDGILPLSSFKEIEAIYNFDMEL
                     KGLFYPIVMLVETALKNRTIDSIVAESSSGIEDILEHQLACYMDYPEDHEKYGNKLDQ
                     YNETRQNVLDTIDYYSDKNEVIKHYLKSDYQIPLWAYFEVITLGQFSRFLGSLTKSSR
                     EKLNQDFTIIPNRSNSLELVVNALIELRNATMHNSAIFDANFSSGVSKALKKQIKQDL
                     GLSTFTCVFIEDYFILLIWTLNILKFDTVVLNNYINQFNEIVERFDVSLNNRDILFKI
                     ISTNRKTSIQQLSKFIDEKRN"
BASE COUNT         1699 a         1043 c          949 g         1970 t
ORIGIN      
        1 attaatcact tgtgatttgt gataagtgat ttgtgattaa tatataaaag ccctctttaa
       61 agggctttta tgtttatttt gaaaaagaga taaaatcaat atatcccttt tccccaattt
      121 ttacaacggc attgtagggc tttttctctt tgtttttgat tccttttacc agggtttctt
      181 ttccctccag taattctttt acattcgttt tggttagttt tttctttcta aaatgttcag
      241 ctaaagtaaa cttacattca ggataatttg aacaaccata aaacgatttt tttaatacaa
      301 tattgttgcc acacttagga cattttccta caaggggtcc cgagcgctta gtgggaattt
      361 gtacccctta tcgatacaaa ttccccgtag gcgctaggga cctctttagc ttcttggaag
      421 ctgtcagtag tatatctaat aatttatctc cattcccttt agtaacgtgt aactttccaa
      481 atttaaaaaa gcgactcata gaattatttc ctcccgttaa ataatagata actattaaaa
      541 atagacaata cttgctcata agtaatggta cttaaattgt ttactttggc gtgtttcatt
      601 gcttgatgaa actgattttt agtaaacagt tgacgatatt ctcgattgac ccattttgaa
      661 acaaagtacg tatatagctt ccaatattta tctggaacat ctgtggtatg gcgggtaagt
      721 tttattaaga cactgtttac ttttggttta ggatgaaagc attccgctgg cagcttaagc
      781 aattgctgaa tcgagacttg agtgtgcaag agcaacccta gtgttcggtg aatatccaag
      841 gtacgcttgt agaatccttc ttcaacaatc agatagatgt cagacgcacg gctttcaaaa
      901 accacttttt taataatttg tgtgcttaaa tggtaaggaa tattcccaac aattttatac
      961 ctctgtttgt tagggaattg aaactgtaga atatcttggt gaattaaagt gacacgagta
     1021 ttcagtttta atttttctga cgataagttg aatagatgac tgtctaattc aatagacgtt
     1081 acctgtttac ttattttagc cagtttcgtc gttaaatgcc ctttacctgt tccaatttcg
     1141 taaacggtat cggtttcttt taaattcaat tgttttatta tttggttgag tactttttca
     1201 ctcgttaaaa agttttgaga atattttata tttttgttca tgtaatctct cctgaagtga
     1261 ttacatctat aaacaaatac agaagttaaa cgatttgttt gtaattttag ttatctgttt
     1321 aaaaagtcat aagattagtc actggtagga attaatctaa cgtatttatt tatctgcgta
     1381 atcactgttt ttagtctgtt tcaaaacagt agatgtttta tctacattac gcatttggaa
     1441 taccaacatg acgaatccct ccttcttaat tacaaatttt tagcatctaa tttaacttca
     1501 attcctatta tacaaaattt tgagggcttg agcaagggct tcagaaatat aaccttcttc
     1561 accttttgaa atctcggcca aatcacgttg gtagcgttcc atttctttgg cattgtaggc
     1621 atcaatcgct tcattctctt ttctggctgc ggcttctttt tctttattac gttttgtaat
     1681 agcttcaatc tcagctgcac gatctgaaac taattgttgt ttctcctgat tcgcttgatc
     1741 tactgcggct tgacctgcac ggttttcagc atcaacagct gcttgaccag cctgattacg
     1801 cctttcaatg gcttcattat ctgcctttgc cttagcaagt ccagcttcat tttcttgttg
     1861 aatggcctga tttttcgcaa caatatcatc tgcctttgtt ttctttgtta gataatctgc
     1921 tacagcttgt tcgttagttg attgaatggt ttcaacagcc ttgccatagt ttgtatagtc
     1981 aagtacagat gtcccatttc ctgatgaaac tacttgttca attactgtca catcagcatc
     2041 tgcatactgg gattttaggt cattgacttt agtatcaacc caagcatttg tctctttacc
     2101 agtttggttt gccccttcgt agacctgtga cagctccata ttttcctgtt caatgcgggc
     2161 tttattcgat tcgtatgtcg ctttgtcagc tttgtagctt tcagtaactt cattgatagc
     2221 cacaacttgg ttttgggcat ctgcttctgc ttttgaaatt tgttggctgg tctctgacgc
     2281 agaagttgta ttccccaaat ccattgggct atcttcaacc gtagaaacac cttcagcctt
     2341 tgcctgttcc actgcttgtt ttaccgtatc atgtggtacg gtgacagcaa ttgcaccgtt
     2401 agattgtcca gttgatgcca tactttcagt ttgttcagaa acaggggttg gttgtgcttc
     2461 tggtaaattt gtggctggat tctccgttcg ttggatgttg gtgtcaactg atgatgtgac
     2521 ttcatcagca tgtgcaaccg ttcctcccca agcaacaaca gccgtcacca tggttccaag
     2581 ggcaacggaa catagagtgc gatatttttt actcttgcga aagacgtgtt tctcgccttt
     2641 ttcctgattg acaagaaagt gatgattaca tgttttggtc ataaatagtc cttcttttct
     2701 tttttatgta gcaacaaatt gtcactcttt cctcatcata aaaaagaagg cttgattttg
     2761 ttatcacaat aaaatgaggg aaaagaaaat gttgctttta taccacaaat attgtaaaat
     2821 tgtagtgtaa aagcaacaag tgggaggccg tatgtcaaaa aaagagattc tactcgattt
     2881 tatagaaaag aacaatggaa ttgtcacaaa caaagattgt aaagcactag gtattccaac
     2941 aatatatctg acaagactag agaaagaagg cattatcttc cgagttgaaa aaggtatttt
     3001 cctaacccaa aacggagact atgatgaata ctacttcttt caatatcgtt ttcctaaggc
     3061 tattttctct tatatttcgg cactgtatct acaacagttt acagatgaaa ttccacaata
     3121 ttttgatgtg acagttccta gaggctaccg ctttaatact cctccagcta atctaaatat
     3181 tcactttgtc tctaaagaat acagcgagct gggaatgact actgtaccta ctcctttggg
     3241 aaacaacgta agggtatatg attttgaacg tattatttgt gattttgtaa tacatcgaga
     3301 aaagattgat tccgaactct ttgtcaagac acttcaatct tatgggaact atcctaaaaa
     3361 aaatctagca aaactctatg aatatgcgac aaaaatgaat actttagaaa aagttaaaca
     3421 aactctggag gttctaatat gaacaaagct aaattaacag cactctgtca taaaatatca
     3481 aagaatactg gtttaacctt taattccgtc atgacctatt acttcctaga agtcattttg
     3541 aaaaaattaa gtcaaagttc ttattcaaat cactatatct tcaaaggagg attcctactt
     3601 tcgaatgtca tcggagttga atctcgtagc actgttgata ttgacttttt attccatcaa
     3661 ataacactct cagaagaaac tgttaaacag caactcaagg aaattttagc agattccgaa
     3721 gaaggtatat cttttgtgat tcaatcaatc acagctatta aagaaagtga tgactatggt
     3781 ggctatcgag caacaatttc gtgccaactt gagaatatta aacaagttat ccatttggat
     3841 attgcgacag gtgatgttgt aactcctcag ccgattacat acgactataa agctattttt
     3901 gatgaagaca attttccaat cattgcttat acaattgaaa caattctagc tgaaaaactt
     3961 caaaccatct attcacgtaa cttcttgaac agtagaagca aagattttta cgatgtttat
     4021 attctttcca aactgaagaa agaagacatt gacttcattc agttgagaaa tgcctgtcag
     4081 agaacatttt catatcgcga aacagaactc gattttgtaa agattattga actactcgag
     4141 aggttcaaat ctgaccctat tcagaataaa caatggcaaa attattcaaa aaaatatagc
     4201 tatacaaaag ggatttcact tgcagatgtt cttgatgaga tgattagtct tattacaatt
     4261 attatttcta ctgactctga ttaaaacttt taactgtcaa actaggtaat cgtgacatta
     4321 aacgaaaagg acatgctaac atttagttat tttgttagca tatccttttt tatttcgtcg
     4381 tatacgcaaa actcaagcta ctatccactc cagataattt acggaaggtg tagttgggat
     4441 tgccattgta gttggtttcg gagataagga atgagccatc tgggtagact ttctccacaa
     4501 aagccacatg tccgtattct gttggtgttc catgtcctcc tcccgcaaag gaaaggatag
     4561 ctcctgcttg tggacttgtc cctgtctctc caccgagact tgcggctgta cgcacccaat
     4621 cttggccatt gcccatggta ctgataatcg gcagcacaac cgataacctc cgaagaatac
     4681 ttaaaaataa aaaaaagagg aggactgacg catcagaccc tcccagacgt gactagcacg
     4741 ccccaattcg atacaactat gataccacta atttcgtttt tcgtcaataa atttacttaa
     4801 ttgttgaatt gatgtttttc tatttgtact gataatctta aagagaatat cacgattatt
     4861 gagtgaaaca tcaaatcgtt caacaatttc attgaattga ttgatgtagt tattgaggac
     4921 tactgtatca aattttagaa tgttcaaagt ccaaattagt agaatgaaat aatcttcaat
     4981 gaaaacacaa gtgaatgtcg ataatcctaa atcttgtttt atctgttttt tgagtgcttt
     5041 agatacaccg cttgaaaaat tagcatcaaa aatcgcactg ttgtgcatgg tagcattcct
     5101 taactcaata agagcgttga caactaactc gagagagttt gacctatttg gaataatcgt
     5161 gaaatcttga ttcaattttt cacgacttga cttagttaaa cttcctaaaa atctactaaa
     5221 ctgtcctaaa gtaataactt caaaataagc ccagagagga atttgataat cactttttaa
     5281 ataatgctta atgacctcat ttttatctga gtaatagtca attgtatcca gtacattttg
     5341 tctagtttca ttatactgat cgagtttatt accatatttt tcatggtctt caggatagtc
     5401 catgtaacaa gctaattgat gttctaatat atcttctatc ccactactag attctgcgac
     5461 tattgaatcg atagtccgat tttttaatgc tgtctctaca agcattacta ttggataaaa
     5521 tagtcctttt aactccatat caaaattgta gattgcttca atttccttaa atgaagaaag
     5581 gggcagaatc ccatctgaat tggatttttt aacgaatcta tatcgtttat aaccatgata
     5641 atatcccata tttaagagtg t
//
LOCUS       DBNFCO010000093         5301 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.093, whole genome shotgun sequence.
ACCESSION   DBNFCO010000093 DBNFCO010000000
VERSION     DBNFCO010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5301
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.093"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            3..73
                     /locus_tag="AC1PIV_001731"
     tRNA            3..73
                     /locus_tag="AC1PIV_001731"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35..37,aa:Gly,seq:tcc)
     gene            104..177
                     /locus_tag="AC1PIV_001732"
     tRNA            104..177
                     /locus_tag="AC1PIV_001732"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:138..140,aa:Ile,seq:gat)
     gene            184..255
                     /locus_tag="AC1PIV_001733"
     tRNA            184..255
                     /locus_tag="AC1PIV_001733"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:217..219,aa:Glu,seq:ttc)
     gene            264..353
                     /locus_tag="AC1PIV_001734"
     tRNA            264..353
                     /locus_tag="AC1PIV_001734"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:300..302,aa:Ser,seq:tga)
     gene            363..436
                     /locus_tag="AC1PIV_001735"
     tRNA            363..436
                     /locus_tag="AC1PIV_001735"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:397..399,aa:Met,seq:cat)
     gene            452..524
                     /locus_tag="AC1PIV_001736"
     tRNA            452..524
                     /locus_tag="AC1PIV_001736"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:485..487,aa:Phe,seq:gaa)
     gene            545..625
                     /locus_tag="AC1PIV_001737"
     tRNA            545..625
                     /locus_tag="AC1PIV_001737"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:579..581,aa:Tyr,seq:gta)
     gene            633..703
                     /locus_tag="AC1PIV_001738"
     tRNA            633..703
                     /locus_tag="AC1PIV_001738"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:665..667,aa:Trp,seq:cca)
     gene            711..783
                     /locus_tag="AC1PIV_001739"
     tRNA            711..783
                     /locus_tag="AC1PIV_001739"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:744..746,aa:His,seq:gtg)
     gene            795..866
                     /locus_tag="AC1PIV_001740"
     tRNA            795..866
                     /locus_tag="AC1PIV_001740"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:827..829,aa:Gln,seq:ttg)
     gene            878..961
                     /locus_tag="AC1PIV_001741"
     tRNA            878..961
                     /locus_tag="AC1PIV_001741"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:912..914,aa:Leu,seq:caa)
     gene            complement(1048..2181)
                     /locus_tag="AC1PIV_001742"
     CDS             complement(1048..2181)
                     /locus_tag="AC1PIV_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HIP6612732.1"
                     /translation="MTVKKAKNGTWTVDISDGFHPVTKKRIRIIRKGFKTKKEALELE
                     QYIRVVELKEKRFDFLVTTDMLFDILEEEDRQNNRKISYISTQRNNYERHIKPYFINT
                     NLNKLSYEHIFEFREYLKIKPKKQNDSSTLSHNTVNKIMILLKKIFDTGVRKSLIDKN
                     PVENIRKLPISKPTINFWNVEEFNEFRKLITSDEISYDLFFTIAFFTGMRLGEIVALT
                     WYDINLITNSIHITKTAYFVNGTNHINSTKTRAGTRRITINHKLARMLADWKEKQKDL
                     LKEFTTDTENLQVIQSTPLPMTKNMIDKKFKQILARNDYLKKIRIHDLRHSHASLLIN
                     QGEDYLVVKERLGHASITTTIDTYSHLYPSKQKTLANKLDDIF"
     gene            complement(2171..2377)
                     /locus_tag="AC1PIV_001743"
     CDS             complement(2171..2377)
                     /locus_tag="AC1PIV_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HIP6612733.1"
                     /translation="MIATVNKNDLVALGFSEGTSKRIIRQGKELLIARGFRVYQNKRV
                     GTIPASIATELLGFDVSLGAHHDS"
     gene            complement(2438..3454)
                     /locus_tag="AC1PIV_001744"
     CDS             complement(2438..3454)
                     /locus_tag="AC1PIV_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HIP6612734.1"
                     /translation="MNTVRIDYFAVTVKNIPPESVLTDILLIPLEDFTLNNWGINKYQ
                     RHYACSEIKVYFNEDRPSMGVFIELKGQGCRQYEEFLDGNENNWIALIGRLYQYSVNF
                     TRLDIAHDIFDGSLDVQRVYDYCKKGLCISKAKHFEYHEKSVLENGERVGETVAIGSR
                     GNQQWCIYNKRMEQLSKQELVEYPSWIRAELRCWQDKANIIAEQLFLKRPLSSIYFEA
                     INGHYRFVKPNATDTNRWRRKKVKWWLDYLKTENQTVLSVERTKPTLRQSEAWTEKQV
                     AKTLAKVYTAKYQAYDVQKAEDYIQGLLKEGLSRLTDNDEKDIEQYIREQNSSPLWGQ
                     KKTT"
     gene            complement(3459..3878)
                     /locus_tag="AC1PIV_001745"
     CDS             complement(3459..3878)
                     /locus_tag="AC1PIV_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612735.1"
                     /translation="MTYNMTDTTLKIGQLDLDMTQFEVPKKIVILSAKVNNRYNEVNG
                     EKIKTEEVTKITCTALDADKVKVLTEMGISTDDLKAINLEIVGNVDKVATLAQNESLL
                     NVPIELVKPKVRLAWNMARSNWAGVKLVCEDIKILGA"
     gene            complement(4214..>5301)
                     /locus_tag="AC1PIV_001746"
     CDS             complement(4214..>5301)
                     /locus_tag="AC1PIV_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HIP6612736.1"
                     /translation="MLIGLNLYEESDNVVTNSATLNFEILPNDIVMVEVPLFGNKFLK
                     LLKNLEEYLVPTLGLPLLSKYEFPDHVIYKLGKIEEIEQYIFNSQTLTRDFFEDIPTP
                     IVKLSNTQQFSLKQNTNLGVYGRTGTGKTIALQWYLFNALAKGCGIDTYLAIVDGKGA
                     DLYALGALLQEELGKQISVGSSPTSLAKLSRQFVKIMDERFEVIKQNSSLNADAYDLG
                     MTPNFLFIDELASIRDSCGSSKQGKELWNEILQNLGLIARKGRQAGCHLCLSTQDPNA
                     ENIPVELRNQISAVLYLGNIGDDRLKMAFSMCELENVPTISDRKGEALFYADGLNSVE
                     PVLTIVPFVDVKTKQDFLQVVRNILPN"
BASE COUNT         1436 a         1100 c          970 g         1795 t
ORIGIN      
        1 aagcgggtgt agtttagtgg taaaactaca gccttccaag ctgttgtcgc gagttcgatt
       61 ctcgtcaccc gctttgaaca tagttcatac ccaaacttgg tttgggcgcg tagctcagat
      121 ggttagagcg cacgcctgat aagcgtgagg tcggtggttc gattccactc gtgcccatta
      181 tatggtccgt tggtcaaggg gttaagacac cgccttttca cggcggtaac acgggttcga
      241 atcccgtacg gactatatta ttcggaggat tacccaagtc cggctgaagg gaacggtctt
      301 gaaaaccgtc aggcgtgtaa aagcgtgcgt gggttcgaat cccacatcct ccttactatt
      361 atcgcgggat ggagcagcta ggtagctcgt cgggctcata acccgaaggt cgtaggttca
      421 aatcctgctc ccgcaatttc tttaagaatt tggctcggta gctcagttgg tagagcaatg
      481 gattgaagct ccatgtgtcg gcggttcgat tccgtctcgc gccattaatt taatattata
      541 tttcggagag atagcgaaga ggctaaacgc ggcggactgt aaatccgctc cttcgggttc
      601 gggggttcga atccctctct ctccatacct ttacgggcat agtttaaagg tagaactaag
      661 gtctccaaaa ccttcagtgt gggttcaatt cctactgccc gtgttatatg gcgggtgtgg
      721 tgaagtggtt aacacatcag attgtggctc tgacattcgg gggttcgatt cccctcactc
      781 gcctatttta atattggggt atcgccaagc ggtaaggcaa gggactttga ctccctcatg
      841 cgttggttcg aatccagcta ccccagttca actatatgcc ggcgtggcgg aattggcaga
      901 cgcgctggac tcaaaatcca gtgtccgcaa ggacgtgccg gttcgacccc ggccgccggt
      961 atagtttaaa agacaaggtt tctaagcctt gtcttttgtt ttatcttttc tattgctctt
     1021 tttcaagttg ccaaaaaatt ccattttcta aaaaatatcg tccaatttgt tcgccaatgt
     1081 cttttgttta ctagggtata agtgggaata tgtatctatt gtagtcgtga tagaggcgtg
     1141 tccaagacgt tcttttacga ctagataatc ttccccttga ttgataagta aagacgcgtg
     1201 agagtgcctt aaatcgtgta ttcgtatctt ttttagatag tcgttcctag ccagtatctg
     1261 cttaaatttt ttatcaatca tattttttgt cattggtagt ggtgtgcttt gaattacttg
     1321 aaggttttct gtatctgttg taaattcttt aagtaagtct ttttgttttt ctttccagtc
     1381 tgcaagcatt cttgctaatt tatgattgat tgtaatacgt ctggtacctg ctctagtttt
     1441 tgtactattg atatgatttg taccgttaac aaagtatgct gtttttgtga tgtgaatgct
     1501 attagtgatt aagtttatat cgtaccaagt taacgcaact atctcgccca atcgcatgcc
     1561 agtaaaaaag gcaatcgtaa agaataggtc ataacttatt tcatcacttg taataagttt
     1621 tctaaattcg ttaaattctt ctacattcca aaaatttata gttggcttac taataggtaa
     1681 ttttcttata ttttcaactg gatttttatc tatcaatgac tttcttacac cagtatcaaa
     1741 aatctttttg agaagtatca ttattttatt gactgtatta tgacttaacg tagagctatc
     1801 gttttgcttt tttggcttta ttttgagata ctctcgaaat tcaaaaatgt gctcataaga
     1861 taatttgttt aagtttgtat ttatgaagta aggtttgata tgtcgctcat agttgtttct
     1921 ttgtgtgctg atataactga tttttctgtt attttgtcgg tcttcttcct caagtatatc
     1981 gaagagcata tcggttgtta ccaaaaaatc aaaacgtttt tcttttaact caacaacacg
     2041 gatatattgt tctaactcta aagcttcttt cttggtcttg aaacctttac gaatgattcg
     2101 tatccgcttt ttggtaactg ggtggaagcc gtcagaaata tcaacagtcc aagttccatt
     2161 ttttgctttc ttaactgtca tgatgagcac ctaaagaaac gtcaaaacca agtaattcag
     2221 tagcgataga agcagggata gttccgacac gcttattttg ataaacccta aaccctcttg
     2281 ctattagaag ctctttcccc tgtctgatga tacgtttaga agttccttca gagaaaccaa
     2341 gggcaactag gtcattctta tttacggttg ctatcattga acactttcct ttcttttgtt
     2401 ataatctagt tagttaattt ttagaggcga cttgttttca agtcgtcttt ttttgtcccc
     2461 ataagggaga actattctgc tctcgaatat attgctctat atccttttca tcattatcag
     2521 ttagccttga caagccctct tttagtagac cttgaatgta gtcctctgcc ttttgaacat
     2581 cataggcttg atattttgct gtatagactt ttgccaatgt cttcgcaact tgtttctctg
     2641 tccaagcctc tgactgccgt aatgtaggct tagttctctc aacgctcaaa acagtctgat
     2701 tttcggtctt tagatagtct agccaccact tgaccttttt tcttctccaa cgattagtat
     2761 ctgtcgcatt tggtttcaca aaacgatagt gaccattgat agcttcaaaa tagatagatg
     2821 acagaggacg ctttagaaac aattgctctg caataatatt cgccttatcc tgccaacatc
     2881 taagttccgc acgaatccat gagggatatt ctacaagctc ttgcttgcta agttgttcca
     2941 tacgtttgtt gtagatacac cattgttgat tacctctgga acctatagca accgtctctc
     3001 caactcgttc tccattttct aagacagatt tctcatgata ctcaaaatgc tttgctttcg
     3061 agatacataa acctttcttg caatagtcat atactcgctg aacatctaaa ctaccgtcaa
     3121 atatgtcgtg agcaatatct aagcgagtaa aattaaccga atactgatac aaccgaccta
     3181 tcaaagctat ccaattattt tcgttaccgt ccaaaaattc ttcatattgg cgacaacctt
     3241 gcccttttaa ttcgataaaa acccccattg aaggtctatc ctcattaaag tacactttaa
     3301 tctcagaaca agcataatgt cgctggtact tgtttattcc ccaattattt aatgtgaaat
     3361 cttctaaagg aattaaaaga atatcagtta aaacactttc tggaggaata tttttaacgg
     3421 ttactgcaaa ataatcaatt ctgactgtat tcatagggtt atgctcctag aattttaatg
     3481 tcctcacata ctaatttaac acctgcccag ttacttcgtg ccatgttcca agctaaacga
     3541 actttcggct taaccaactc aatcggaaca ttcaaaagtg attcattttg agcgagcgta
     3601 gcaaccttat ctacattacc tacaatttct aggttgatag ctttcaagtc atcagtagaa
     3661 attcccattt cagttagaac tttcacttta tcggcatcaa gggcagtaca agtgattttc
     3721 gtaacttctt cagttttgat tttctcgcca ttaacctcgt tatacctatt atttacttta
     3781 gcagatagaa taacaatttt tttaggcact tcaaactgtg tcatatccaa atcaagttgc
     3841 ccaatcttaa gggtagtatc tgtcatattg taagtcataa taattactcc attttctatt
     3901 caaaaagtcg tatcctacac gaaaagcgac taaatccctt ctcccacaag ggtttcaatg
     3961 acttcggtat aaccaacaag ccgtaacccc ttacgtatca agggtttaga gtacatttca
     4021 tgtatgtgtg caccccctat tagagtacat ttcatgtatg tgtgcacccc ctattagtaa
     4081 tgggggtatt tttctgacct cctgcaaagc agtcggttgg ctctttctcc tagcgaaaag
     4141 aggaacgctc cgctcgattc tgccccctgg gcaatcgtcc cccctatttc gctagtccga
     4201 aagaccgtca ttattagttt ggcagtatat ttctaactac ctgtaaaaaa tcttgttttg
     4261 ttttaacatc gacgaacggg acgatagtta gtacaggctc aacagaattt aaaccgtcag
     4321 cataaaagag tgcttcgcct ttcctgtctg aaattgtagg aacattttcc agttcacaca
     4381 tactaaaagc cattttcaat cggtcgtccc ctatatttcc gaggtataaa actgctgata
     4441 tttggtttct aagttcaaca ggaatattct ctgcatttgg gtcttgggta ctaaggcaga
     4501 ggtggcaacc tgcctgccgt cctttgcgtg caatcaagcc taagttttgc agaatttcat
     4561 tccatagctc tttaccttgt ttactagaac cacaactatc acgaatagaa gcaagctcat
     4621 caataaacaa aaaattaggg gtcattccta aatcataggc atcagcattt agcgaactgt
     4681 tctgcttgat aacctcaaaa cgttcatcca taatttttac aaactgtctt gatagctttg
     4741 ctagtgaagt aggagaagag cctactgaaa tttgttttcc cagttcttct tggaggagtg
     4801 ccccaagagc atataagtca gctcctttac catcaacgat agctagataa gtatcaatac
     4861 cgcacccttt ggcaagtgca ttaaataagt accattgtag agctattgtc ttccctgtac
     4921 ccgtccttcc atatactcct aaattagtat tctgttttag agaaaattgc tgagtattgg
     4981 atagtttaac tattggcgta ggtatgtctt caaaaaaatc tctagtcaat gtttggctat
     5041 tgaatatata ctgctcaatt tcttctatct ttccaagttt ataaataaca tggtcaggaa
     5101 attcatattt ggatagtaga ggtagaccca aggttggaac aagatattct tcaagatttt
     5161 ttagaagttt taaaaactta ttcccaaaca atggtacttc gaccattaca atatcattgg
     5221 gcaagatttc aaagtttaat gttgcactat tggttactac attatcactt tcttcgtata
     5281 aatttaggcc aatcagcata t
//
LOCUS       DBNFCO010000094         5240 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.094, whole genome shotgun sequence.
ACCESSION   DBNFCO010000094 DBNFCO010000000
VERSION     DBNFCO010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5240)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5240)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5240
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.094"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(1..138)
                     /locus_tag="AC1PIV_001747"
                     /pseudo
     CDS             complement(1..138)
                     /locus_tag="AC1PIV_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011148688.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(360..3458)
                     /locus_tag="AC1PIV_001748"
     CDS             complement(360..3458)
                     /locus_tag="AC1PIV_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014917230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III restriction-modification system
                     endonuclease"
                     /protein_id="HIP6612737.1"
                     /translation="MKLQFKQQQFQLDAVASVVDVFVGQGKHSGFDYHMDKGQGMGAE
                     LDMNFIGFRNAPIQLSQETVSQQVRAKQLSYGLKPSENLSIQKVDGRPSYNLTIEMET
                     GTGKTYTYIRTLMELNKQYGWLKFIIVVPSIAIREGVLKSFEIMADHFQMEYGKKPRY
                     FVYDSSRLGELDKFANSSDIQVMIINSQAFNATGADARRIHTEQESFRWRKPIDVIAA
                     TNPILIIDEPQSVEGKKTKERLEDFKPLFTLRYSATHKDKHDMIYRLDALDAYNKKLV
                     KKIAVKTVEQTATTGTQGYLYLQELVPQKSGSPKARIEFEVRTKSGDVKWVTKLVEEP
                     FALFEESGNLPAYQGGWTLSHFDAREGENSIQIGANRKLYVGEVIGETNEDDIRRIQI
                     RETIASHLQKEERLYKRGIKVLSLFFIDEVAKYKCYDEQNDAYNSTYAQMFEEEYEAQ
                     VKALLADLNLHGSNFWHYLNKHQEGNPVHAGYFSVDKIKKSDKVKFVDYKSATEKKNN
                     QSNDKDAYDLIMKDKERLLSFEEPIRFIFSHSALKEGWDNPNVFQICTLKNTGTETEK
                     RQKIGRGMRLAVDQKGVRQDEELLGADVHNINKLTVIANESYEDFAKNLQRELREILA
                     DRPSKVEVDFFVNKVLENEAGQKLTVTKEVAKEIERQLIKQDYIDSKGNLTATYFEQK
                     ETSQFTLSENLAGYEVAVKDILETIYDANRYQIERENDSEVVFAREINPDNYNRQEFK
                     RLWESIHHKSTYYVEFDDEELIEKSVKALNESLFVKKPSYMITEAEAREMQAKHGLDF
                     KVNKNGKRQSVLDKSSIQLRYDLLGEIASRTELKRKTVANILKQISPSKFDMFSYNPE
                     AFIQQVSRLINEQKASQVIEHIRYNILEETFDSSIFTDNPLSGKVSDANMLKSEKGVY
                     NYVKVDSGTERKFKEDLERFDDVMVYAKLPSKFKISTPLGDYNPDWAIAFRDGSVKHV
                     YFVAETKGSMSSLQLKGAELAKIECAKAHFKALKEKGLIADDRIYDVVDSYEKLLEIV
                     RG"
     gene            complement(3462..5176)
                     /locus_tag="AC1PIV_001749"
                     /pseudo
     CDS             complement(3462..5176)
                     /locus_tag="AC1PIV_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003615287.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006306 - obsolete DNA methylation
                     [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
BASE COUNT         1393 a         1236 c         1013 g         1598 t
ORIGIN      
        1 tacacaaacg ccggaatatt tctcccaaac tacttcgata ttgattatag atgatttttc
       61 gtctatactt aggtgtgaag acaatgtggt agaacacagc cactttgtat gtgataaatt
      121 atgtgccttt tgtgccatac ttttctcctc tcgctttaca ataggcttga atacctttat
      181 tgtatcgcgt ttggagtttt ttatgtatga gcggctagtt tttgcccagc ctctttcagg
      241 ggacaacaaa agccttgact atggcaacaa tgcccaccag ataacaaatc gcaaatgtaa
      301 aaaacagaaa cgcacccata aatattctcc ttcagtggcg agaaggattg ctcagcaacc
      361 tatcctctca cgatttctaa taatttttca taggaatcaa ccacatcata aatccgatca
      421 tccgcaatca atcctttttc ttttagggct ttgaagtggg cctttgcaca ctcaatcttt
      481 gccaactccg cccctttcag ttgcaaacta gacatggaac ctttggtttc agctacgaag
      541 taaacatgct tgaccgaacc atctcggaag gcaatggccc agtctggatt gtaatcaccc
      601 agcggtgtgg aaatcttaaa cttgctaggc aatttggcat agaccatgac atcgtcgaat
      661 cgctccaagt cctctttgaa cttcctctcc gttccagaat caaccttcac ataattataa
      721 acacccttct cagacttgag catatttgca tctgacacct taccactcaa aggattgtcc
      781 gtaaaaatag aactatcaaa agtttcctct aggatattgt agcggatatg ctcaatcacc
      841 tgactcgcct tttgctcatt gatgagccta ctaacttgtt ggataaatgc ctcagggtta
      901 taggaaaaca tatcaaactt gcttggcgaa atctgcttca aaatattggc gactgttttc
      961 cgtttcaact ccgtgcgact ggcaatttca cccagcaaat catagcggag ttgaatagaa
     1021 gacttatcca gcacagactg acgcttgccg ttcttattta ccttgaaatc caaaccgtgt
     1081 ttcgcctgca tttcccttgc ttcagcctct gtaatcatgt aactaggctt tttaacaaac
     1141 aaggactcat tcaaggcctt aacagacttt tcaatcaact cctcatcatc aaattcgaca
     1201 tagtaggtgg acttgtgatg aatactttcc cacaaacgtt taaactcttg acgattgtag
     1261 ttatcagggt tgatttctct tgcaaaaacc acttccgaat cattttcacg ttcaatctgg
     1321 tagcgattgg catcgtaaat cgtttctaga atatctttta cagccacttc atagcctgcc
     1381 agattttcag atagagtaaa ctgacttgtt tctttttgtt caaaataagt agcggtcaga
     1441 ttccccttgc tgtcaatata atcttgctta atcaactggc gttcaatctc tttagccact
     1501 tccttggtga cagtcagttt ttgaccagct tcattttcca agaccttgtt gacaaaaaaa
     1561 tccacttcca ccttgcttgg tcgatcagcc aagatttccc tgagttctct ttgcaagttc
     1621 ttagcaaaat cttcatagct ttcattggcg atgacggtca acttgttaat attatgaaca
     1681 tcagctccta aaagctcctc atcctgacga acaccttttt ggtcgacggc tagacgcatc
     1741 ccacgaccaa tcttttgtcg tttttctgtt tctgtacctg tatttttcaa ggtacaaatc
     1801 tggaagacat taggattgtc ccagccttct ttgagggctg agtgagaaaa gataaagcga
     1861 ataggttcct caaaagacag cagacgttcc ttgtccttca ttatcaaatc ataggcatcc
     1921 ttgtcgttag actggttatt tttcttttcc gtagcagact tgtagtccac aaacttgacc
     1981 ttatccgatt tttttatctt atcgacagag aaataacctg catgaacagg attgccttct
     2041 tggtgcttgt tgagataatg ccaaaagtta cttccatgaa ggttgagatc agccaataaa
     2101 gccttgacct gggcttcata ctcttcttca aacatctggg cataggtgct attgtaggca
     2161 tcattttgct catcatagca cttatacttg gcaacttcat cgatgaagaa aagggatagc
     2221 accttgatac ctcgtttgta aaggcgttct tctttttgca ggtgactggc aatggtttcc
     2281 cgaatctgga tacgacggat gtcatcttcg ttggtttccc caatcacttc gcccacatag
     2341 agtttgcgat tggcaccgat ttgaatggaa ttttcacctt cacgcgcatc aaaatggctc
     2401 aaggtccaac cgccttgata ggctggtagg ttgcctgact cttcaaaaag agcaaaaggc
     2461 tcttcaacca atttggtcac ccatttgaca tcgcctgact tggtccgcac ttcaaactca
     2521 atccgagcct taggagaacc tgatttttgc ggaaccagtt cttgcagata aaggtagcct
     2581 tgtgttcctg tggttgcagt ctgctccacg gtcttaacgg caatcttctt gaccaacttt
     2641 ttattgtagg cgtccagggc atccagacga taaatcatat cgtgcttgtc cttatgagtg
     2701 gctgaatagc ggagagtaaa taggggcttg aagtcctcca agcgttcttt agtctttttc
     2761 ccctcaaccg actgaggctc atcgataatc aaaataggat tggtcgccgc aatgacatca
     2821 atcggctttc tccagcggaa actttcctgc tcggtgtgaa tacgacgggc atctgctcca
     2881 gtggcattaa aggcttgtga gttgataatc ataacctgaa tgtccgagga gttggcaaac
     2941 ttgtccagct cgcccaaacg gctagaatca tagacaaaat agcgtggctt cttgccatac
     3001 tccatctgga aatggtccgc catgatttca aaggacttga gcactccctc acgaatagca
     3061 atgctcggca ccacgatgat aaacttgagc caaccatact gcttattgag ctccatcaag
     3121 gtacggatat aggtgtaggt cttccctgtc cccgtctcca tctcaatagt caaattgtaa
     3181 gacggacgac catccacttt ttgaatagac aagttttcag atggtttaag gccatagctg
     3241 agctgcttag ctcgaacctg ctggctgaca gtttcctgcg aaagctgaat gggagcattg
     3301 cggaaaccga taaaattcat gtccagttcc gcacccattc cctgaccttt atccatgtgg
     3361 taatcaaaac cgctatgttt gccctgacca acaaaaacat ccacaacaga ggccaccgca
     3421 tctaactgaa attgctgctg cttaaattga agtttcatct cctacaccac cttcactttg
     3481 gtatttggtg cttcttcttt gaagatttgg cccaggttga ttttggctgc ggagttggca
     3541 aaggattcgt ccttaaaaac agcacgaagg ggctctgctt tggcgatttg acagaggacg
     3601 ctttctgaaa tctcatccgc aaagcaggca atcaaggcac catctgctac attataaatg
     3661 gctgtaccgt caatctgggt tttcgtaatc ggaagagata attccatgcc ccatgtcagc
     3721 ataatctgga agagcaggtc aaggtctgtc cgaccgtctt tgatgttgga aacactgtca
     3781 aataggcttt cttggctaaa gctgtttggt gtttggctaa catccttgaa gtttgaagtg
     3841 tctagcttat aagccctgaa gccaaaatct tgcttgccga ctgtttctgg gtgttcttct
     3901 tgaatctttt tagcagcccg acggatccgc tcacgagaaa tctggtcaat ggtttcatag
     3961 ccagcctcct tggcagcgga cttgtctgcc acctgctcgt ccagcgtaca gagtatgtac
     4021 ttacgattac cgccatcttc tgcattcaac tgcataacag catcagcagt ggttgcagaa
     4081 ccagcgaaga agtcgaggat caggccgtct ttttctgaat acaattgaac aatttgcttc
     4141 atcaacggaa ctggttttgg ataggtgaaa tatgccttac catcaaataa ttttttcaag
     4201 tcttggctag cagactgaga atgaccgaca tcagcgtact tccaaatcgt cattggagtt
     4261 actgtatttt ttacttctga taaaaatctt tttatcctag gcacattatc tccattagcc
     4321 ccgaaccaaa tacgattatc agcaataaat tcttcaaatc tttctttact cagcaaccaa
     4381 cttctcccgc ttggaggaaa aatagatctt ccgcttggag aaattatctc ataaatattt
     4441 gaaggaactg ctggtcctac tgataaatca ccacttgtcc aaggtcctct aacatcatta
     4501 tcaggatttt ggtatctact atttgagtct tcgcttctag gtattccatg attgacagca
     4561 aattctacat tttttgcata tactaaaata taatcatgac tttctgaaaa atgttttttc
     4621 aagtttacag gtgcaaatgc tctctcccag atgacatcag caacaaaatt ctcctcccca
     4681 aatatctcat cacagatagc tttgaggttg gcttgttcgt tatcgtcaat ggagattaaa
     4741 gataactcca ctatctttga ggaggttgcg ggcaaggact aggcgagagt acatcatatt
     4801 gagccagtcg gaatgatagc gggcggagga tttttcattc ttggtcaagc ccacccgttg
     4861 caaaccgtcc tcatcacgca gatccatttc atctgccagt tcttcctcgc tcatctggaa
     4921 tttatccgaa tagacaaagt cctttcctgt attgtaaggt gggtcaatgt aaatcatatc
     4981 aatcttgccc agataagact cctgcaagac cttgaggact tccaggttgt cccctgttat
     5041 aaagacattt tcagacttgt caaagtcaac actttcctca agatctgggc gaagggtctt
     5101 ggtggtcggt ttacctgcca ttttcatcac tactttctgt tagaacctca ggaaaaagct
     5161 gaccaatttt tgcaatgttg tctgataaaa catcttttga ccttaggtct agcttttcaa
     5221 cttgagtgta gtctccaagc
//
LOCUS       DBNFCO010000095         5233 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.095, whole genome shotgun sequence.
ACCESSION   DBNFCO010000095 DBNFCO010000000
VERSION     DBNFCO010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5233)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5233)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5233
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.095"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            241..621
                     /locus_tag="AC1PIV_001750"
     CDS             241..621
                     /locus_tag="AC1PIV_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612738.1"
                     /translation="MSFINQFKSQSKTVLATVAISVAILGFAGGMSISKSSAGVSTQS
                     QVTLAQNGSVAKSGQVATQGMLPGQGGATQDISPGQGITPPDATSGATQSNSSTSSDE
                     VNALKKRNQEIKAQISGDSSSSNQ"
     gene            815..1486
                     /locus_tag="AC1PIV_001751"
     CDS             815..1486
                     /locus_tag="AC1PIV_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HIP6612739.1"
                     /translation="MIKILLVEDDLSLSNSVFDFLDDFADVMQVFDGEEGVYEAETGV
                     YDLILLDLMLPEKDGFQVLKELREKGVTTPVLITTAKESLEDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRAGKFNENTLTFGDVTVDLSTNMTMVNGEEVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTTFGENLQTLRSVGY
                     ILKNA"
     gene            1479..2858
                     /locus_tag="AC1PIV_001752"
     CDS             1479..2858
                     /locus_tag="AC1PIV_001752"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIP6612740.1"
                     /translation="MPKRIGKLVYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMY
                     QNSDNTLKRIKEEPAMAVGFAIARTYEPNSVFILQDSPTSEETTSSSSDSMPVPKEQK
                     NTRDGDQLRLGVNTHVLLYSKSGEMVNPDTFTGLANLPLDKEKLGEIKETTVESSFGM
                     SEDYRYITIGLATDELGYYSSYDIKYATILVNVSQIKSSIESYESTVAIVMVSAWLIS
                     ILASIYLSNLSMRPILISYQKQKDFVENASHELRTPLAVLQNRLESLFRHPETTILES
                     SESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMIDVQPNYFDEIFANYLMIAEENG
                     KTLTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDDDGTIQIAANIKDKLVCFTVID
                     NGLGISDVDKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKNLDGEISVRDNQPKG
                     TIFEVRLPK"
     gene            3189..4418
                     /locus_tag="AC1PIV_001753"
     CDS             3189..4418
                     /locus_tag="AC1PIV_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HIP6612741.1"
                     /translation="MRKVSRGVLTILLSATVLSACSGGGQELSERLEAAKIEFSKEKK
                     QLEAELTALKEEVQGNFYYQQLDTDKERRVYLQFVNGLSKRMQVIDIDSVNDEIYSRV
                     YFSVAHDYPEFYWLTDEAAMSGGVDILDLEEPVYPTDLSPTRNKIEEEVNKILAQAPT
                     GSDYEKVKYFYEVIIKQTDYDLEALQTNSVTWRSQGITSVLLDKKSVCAGYSRTFQYL
                     CKKAGIDCIYVTGIAKNGQNGEFGHAWNLVKINGQYYGVDTTWGDPVFDQAISGEAHT
                     DISYDYLCVPDEILERSRIADTDLLDYWGEEQYYEPRALTYPKCTDNSLNYYVQKGVY
                     FTSFDEAAVLQSITDQRLQGTNKVVLQFGTAEAMQQMITLASTENNAIFQALGDVGEY
                     QYYYNDQTYTFELADWF"
     gene            4831..>5233
                     /gene="tnpA"
                     /locus_tag="AC1PIV_001754"
     CDS             4831..>5233
                     /gene="tnpA"
                     /locus_tag="AC1PIV_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011148688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISSsu4 family
                     transposase"
                     /protein_id="HIP6612742.1"
                     /translation="MAQKAHSLSHTKWLCKYHIVFTPKYRRKIIYNQYRSSLGEIFRR
                     LCTYKGVEIIEGHLMPDHVHMLVSIPPRLSVSSFIGYLKGKSALMMFDKHANLKYKFG
                     NRHFWAEGYYVSTVGLNEATIKKYIQEQEKHD"
BASE COUNT         1715 a          873 c         1079 g         1566 t
ORIGIN      
        1 caccctcgac ttaacaagac acctctactt tatcataaag aaaaagtagt gagtactttc
       61 tcccgtcgga gatttcctca ctactaatct tagtatgttt ttgtgtaatg gacttttata
      121 aaaaatgctg aatttcttta gcttgtttta agttttcaat actatactat tatcatcagg
      181 tgaagaggag ttatttaaca ggtctcattc tgataatatt ctattgaaaa ggggaatttc
      241 atgtcattta ttaatcaatt taagtcacag tcaaaaacag tactagctac tgttgctatt
      301 tcagttgcta tcttgggctt tgcaggggga atgagtattt ctaaaagctc agcaggagtt
      361 tcaacacaaa gtcaggtaac tttggcgcaa aatggttccg tagctaagag tggacaagta
      421 gctacccaag gcatgctacc aggtcaggga ggagctacac aagatatatc accgggacaa
      481 ggtataactc ctcctgatgc gacaagtgga gcaactcagt caaactcgag tacttcttct
      541 gatgaagtga atgctttaaa aaagaggaat caagaaatta aagctcaaat ttcaggagat
      601 agtagttctt ctaatcaata aatattgaga tttcgatttt tacttattcc atgatataat
      661 gaactcgtat caataaatag ttagataaag actaccttat cattcatttt tcagatggtc
      721 atagtagtac tttatctaac catttctctt aaagaccgtg acctgtccca ggtctttggt
      781 ttgtttatta aaccgaaacg taaggaagtg tatgatgatt aaaatattgt tagtggaaga
      841 tgatttaagt ctatcaaatt ctgttttcga tttcttagat gattttgcgg atgttatgca
      901 ggtttttgat ggtgaagagg gcgtttatga ggcggaaaca ggcgtttatg atttgattct
      961 tttggattta atgttacctg aaaaagacgg ctttcaagtc ttgaaagagt tacgtgaaaa
     1021 gggggttacg acaccagttc tgattacaac agccaaggaa agtctagagg ataaaggcca
     1081 tggttttgaa ttgggggctg atgactattt gacaaaaccg ttttatttag aagaattgaa
     1141 gatgcgaatt caagctctat taaaacgagc gggtaagttt aatgaaaaca cactaacctt
     1201 tggagatgtg acagttgacc tatctacaaa tatgacgatg gtaaatggcg aagaagttga
     1261 actgttagga aaagaatttg atctactagt ttatttcttg caaaatcaaa atgttatttt
     1321 gccaaaaaca caaatttttg accgtatttg gggctttgac agtgatacta caatttcagt
     1381 agtagaggta tatgtttcta aaattaggaa aaagttgaaa ggaacgactt ttggggaaaa
     1441 tcttcaaacc ctgcgtagtg tcgggtacat tctaaaaaat gcctaagcga atcggaaaat
     1501 tagtgtatac ggataaattt tccttcttta tccgttattt tgcagtattt accctgattt
     1561 ttggcttgat gacagctatc atttttcaat taatgcgttc aactatgtat caaaattcag
     1621 ataatacctt gaaacggatt aaggaagaac cagcgatggc tgttggtttt gcgatcgcaa
     1681 gaacctatga gcccaactct gtctttatac ttcaagatag cccaactagt gaagaaacga
     1741 cgagctctag ctcagatagc atgcctgttc ctaaagaaca aaaaaatact agagatggag
     1801 atcagctgag attaggtgtc aatactcatg tcttactcta tagtaaaagt ggagaaatgg
     1861 tcaatccgga tacttttact ggtttggcca acctaccgtt agataaggaa aaattgggtg
     1921 aaattaagga aactacggtt gaatcaagtt ttggtatgtc tgaagattat cgctatataa
     1981 cgattgggct ggctacagat gaactaggtt attattcgtc ctatgatata aaatatgcga
     2041 caattttggt gaatgtcagc caaattaaat cttccattga gagctatgaa tcgacagttg
     2101 ctattgttat ggtatcagct tggttgattt ctatactagc aagtatttac ctatcgaatc
     2161 ttagcatgcg tccaatccta attagttatc aaaaacaaaa agacttcgtt gaaaatgcta
     2221 gtcatgagtt acgcacaccg ttggcagttc ttcaaaatcg cctggaaagt ctatttcgtc
     2281 atcccgagac aactattttg gaaagtagtg aaagcatcgg atctagttta gaagaagttc
     2341 gaaatatgcg actattaaca acgaacttgc tcaatttggc tcgtcgtgat gatggcttaa
     2401 aagtcgatat gatcgatgtc caacccaact attttgatga aatctttgct aattacctta
     2461 tgattgccga agaaaatgga aaaactctaa cagttaataa tttgattcat cagccaattc
     2521 gaacagacaa ggttttgatt aaacagttgc tcaccatttt gtttgacaac gctatgaagt
     2581 ataccgatga tgatgggaca attcaaatag cagctaatat caaggacaaa ctagtttgtt
     2641 ttacagttat tgacaatggt ttgggaatca gcgatgtcga taaaaagaaa atctttgatc
     2701 gcttttaccg agttgacaag gctagaacac gtcaaaaagg tggatttggt ttaggtttat
     2761 ctttagctca acaaattatt aagaatctag atggtgagat ttctgtgaga gataaccaac
     2821 cgaaaggaac tatttttgag gtacgtttac ccaaataact aaccattcat caagattaga
     2881 ggttgggtaa aaaatccagc ctttcttctc aaagttcgct ctatttccaa tttccaactt
     2941 ccaactgtct cccaggtagt tttgtagcga actctgttcg ctctatctcc agcctccaaa
     3001 ggtttgggga actgtttcag ctggtcacct aaaaataaga aagtgaccat agaaaatcga
     3061 acctaaatgt ttggaagtga ggggaattct ttttcgatct attgaattct ttccactccc
     3121 tttttgtttt gtgtagttcg tcagaagtct cctgattatg ttatacttaa acaagaatgt
     3181 aggtaaatat gaggaaagtt tctcgtggcg ttttaactat attattatca gcgacagtcc
     3241 tttctgcttg ttcaggagga ggacaagagc tgagtgaacg tttggaagca gctaaaattg
     3301 aattttctaa agaaaaaaag caactagaag cagaattaac agcattaaaa gaagaggttc
     3361 aaggaaattt ctactaccaa caattggata ctgataagga acgtcgtgtc tatctccaat
     3421 ttgttaatgg gctcagcaag cggatgcaag tgatcgatat tgattctgtt aatgatgaaa
     3481 tatattcgcg cgtctatttt tctgtcgctc atgattatcc agaattttac tggctaactg
     3541 atgaagcagc aatgagtggc ggagttgata tattggattt agaagagcca gtgtatccga
     3601 ctgatttatc tccgacacga aataaaatag aagaggaagt gaataagata cttgctcagg
     3661 caccgacagg gtcggactat gagaaggtta aatattttta cgaggtgatt ataaagcaaa
     3721 cggattacga ccttgaagcc ctacaaacca actctgtcac gtggagaagc caaggaatta
     3781 ccagtgtgct attagataag aaatccgttt gtgctggcta tagtcgcacc ttccaatatc
     3841 tatgtaaaaa agcaggcatt gattgtatct atgtcacagg gattgcaaaa aatgggcaaa
     3901 acggtgagtt tgggcatgct tggaatctag tcaagataaa tggacaatac tatggtgtcg
     3961 atacgacttg gggagatcca gtttttgatc aagctataag tggagaagcg catacagata
     4021 tttcatacga ttatctatgt gtccctgatg aaatattaga gagaagtaga attgctgata
     4081 ccgacctact cgactactgg ggagaagaac aatattacga acctagagca ttgacctatc
     4141 caaagtgtac agataattca ttgaattact atgttcaaaa gggagtttat ttcacaagct
     4201 ttgatgaagc tgcagtttta cagtccatca ctgaccagcg gctacaaggt acgaataaag
     4261 tagtcttgca attcggaaca gcagaagcaa tgcaacaaat gattacattg gcctctactg
     4321 aaaataatgc tatttttcag gctttgggcg atgtaggaga gtatcagtac tattataatg
     4381 accaaaccta tacatttgaa ctggcagatt ggttttaagg aattagtttg aatctccagg
     4441 agcgtgttct tccctaataa taaaaaatag ggagtgggaa agacatccat gatggctccg
     4501 cctcacccac agaataatga aaacgaacat aaagccctca ctaggtgtat aatcttagtg
     4561 agggctttac ggttgacgag ttaatgatgt tactcatcga gggaaaactg atccactttg
     4621 tcccgcctcc ttatgatgga aaaaataaaa aaaaaggaaa cccaaaggtt tcttttttaa
     4681 ttatgtgact tttagtccgt cacgctccgt aaggtgcgtg acaaataaac cacccgctat
     4741 gcgggtgcgc gacgaaggtt acaccaaaaa aactccaaac gcgatacaat aaaggtgttc
     4801 aagcctattg taaagcgaaa ggagaaaaat atggcgcaaa aggcacatag tttatcacat
     4861 acaaagtggc tgtgtaaata ccacattgtc ttcacaccta agtatagacg aaaaatcatc
     4921 tataatcaat atcgaagtag tttgggagaa atattccgac gtttgtgtac ttataaaggc
     4981 gtagaaatta tcgaaggaca tctgatgccg gatcatgttc atatgttagt cagtattcct
     5041 ccgcgattaa gtgtatcaag ctttatagga tatttaaaag gtaagagtgc tctaatgatg
     5101 tttgataaac acgccaatct caaatacaaa tttggtaatc gtcatttctg ggcagaggga
     5161 tattatgtaa gtacggttgg actaaatgaa gccacaatta agaaatatat acaagaacag
     5221 gaaaaacatg ata
//
LOCUS       DBNFCO010000096         5225 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.096, whole genome shotgun sequence.
ACCESSION   DBNFCO010000096 DBNFCO010000000
VERSION     DBNFCO010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5225)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5225)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5225
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.096"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(<1..96)
                     /gene="rrf"
                     /locus_tag="AC1PIV_001755"
     rRNA            complement(<1..96)
                     /gene="rrf"
                     /locus_tag="AC1PIV_001755"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            complement(183..3086)
                     /locus_tag="AC1PIV_001756"
     rRNA            complement(183..3086)
                     /locus_tag="AC1PIV_001756"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            complement(3366..3438)
                     /locus_tag="AC1PIV_001757"
     tRNA            complement(3366..3438)
                     /locus_tag="AC1PIV_001757"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3403..3405),aa:Ala,seq:tgc)
     gene            complement(3492..5040)
                     /locus_tag="AC1PIV_001758"
     rRNA            complement(3492..5040)
                     /locus_tag="AC1PIV_001758"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT         1179 a         1507 c         1061 g         1478 t
ORIGIN      
        1 aacagggggc aacccccaac tacttcaggc gttctagggc ttaactgctg tgttcggcat
       61 gggtacaggt gtatctccta ggctatcgtc acttaactac tgagtcttgt caactcaaaa
      121 ttgaatatct atattctaac aagaaaccga tcgcttgtca atattgactc tagtttattt
      181 ctttggataa gtcctcgagc gattagtatt ggtccgctac atgtgtcgcc acacttccac
      241 ttccaaccta tctacctgat catctctcag ggctcttact aacataaagt tatgggaaat
      301 ctcatcttga ggtgggtttc acacttagat gctttcagcg tttatcccgt ccctacatag
      361 ctacccagcg atgcctttgg caagacaact ggtacaccag cggtaagtcc actctggtcc
      421 tctcgtacta ggagcagatc ctctcaaatt tcctacgccc gcgacggata gggaccgaac
      481 tgtctcacga cgttctgaac ccagctcgcg tgccgcttta atgggcgaac agcccaaccc
      541 ttgggaccga ctacagcccc aggatgcgac gagccgacat cgaggtgcca aacctccccg
      601 tcgatgtgaa ctcttggggg agataagcct gttatcccca gggtagcttt tatccgttga
      661 gcgatggccc ttccatacgg aaccaccgga tcactaagcc cgactttcgt ccctgctcga
      721 gttgtagctc tcgcagtcaa gctcccttat acctttacac tctgcgaatg atttccaacc
      781 attctgaggg aacctttggg cgcctccgtt accttttagg aggcgaccgc cccagtcaaa
      841 ctgcccgtca gacactgtct ccgataggga taacctatcc gggttagagt agccataaca
      901 caagggtagt atcccaacag cgcctcagtc gaaactggcg tcccgacttc gtaggctcct
      961 acctatcctg tacatgtggt acagatactc aatatcaaac tgcagtaaag ctccatgggg
     1021 tctttccgtc ctgtcgcggg taacctgcat cttcacaggt actaaaattt caccgagtct
     1081 ctcgttgaga cagtgcccaa atcattacgc ctttcgtgcg ggtcggaact tacccgacaa
     1141 ggaatttcgc taccttagga ccgttatagt tacggccgcc gtttactggg gcttcaattc
     1201 agatcttcgc ttgcgctaaa ccctcctctt aaccttccag caccgggcag gcgtcacccc
     1261 ctatacatca tcttacgatt tagcagagag ctgtgttttt gataaacagt tgcttgggcc
     1321 tattcactgc ggctgacttt aagccagcac cccttctccc gaagttacgg ggtcattttg
     1381 ccgagttcct taacgagagt tctctcgctc acctgaggct actcgcctcg actacctgtg
     1441 tcggtttgcg gtacgggtag agtatgatac atcgctagaa gcttttctcg gcagtgtgac
     1501 gtcactaact tcgctactta acttcgctcc ccatcacagc tcaatgttac agatacaagc
     1561 atttgactca tatcacacct cactgcttag acgggcactt ccaatcgccc gctttagtta
     1621 gcctactgcg tccctccatc acttcatact ctagtacagg aatatcaacc tgttgtccat
     1681 cggatacacc cttcggtctc tccttaggtc ccgactaacc cagggcggac gagccttccc
     1741 ctggaaacct tagtcttacg gtggatggga ttctcaccca tctttcgcta ctcataccgg
     1801 cattctcact tctatgcgtt ccagcactcc tcacggtata ccttcttcac acatagaacg
     1861 ctctcctacc ataacactaa agtgttatcc acagcttcgg taaattgttt tagccccggt
     1921 acattttcgg cgcagggtca ctcgactagt gagctattac gcactctttg aatgaatagc
     1981 tgcttctaag ctaacatcct agttgtctgt gcaaccccac atccttttcc acttaacaat
     2041 tattttggga ccttagctgg tggtctgggc tgtttccctt tcgactacgg atcttagcac
     2101 tcgcagtctg actgccgacc ataaatcatt ggcattcgga gtttatctga aatcagtaaa
     2161 ccgagatggc cccctcatcc aaacagtgct ctacctccaa gattctcaaa tgtcgacgct
     2221 agccctaaag ctatttcgga gagaaccagc tatctccaag ttcgtttgga atttctccgc
     2281 tacccacaag tcatccaagc acttttcaac gtgccctggt tcggtcctcc agtgcgtctt
     2341 accgcacctt caacctgctc atgggtaggt cacatggttt cgggtctacg acataatact
     2401 aatccgccct attaagactc ggtttcccta cggctccgtc tcttcaactt aacctcgcat
     2461 catatcgtaa ctcgccggtt cattctacaa aaggcacgct ctcacccatt aacgggctcg
     2521 aacttgttgt aggcacacgg tttcaggttc tatttcactc cccttccggg gtacttttca
     2581 cctttccctc acggtactgg ttcactatcg gtcactagag agtatttagg gttgggagat
     2641 ggtcctcccg gattccgacg agatttcgcg tgtctcgccg tactcaggat actgctaggt
     2701 ataaaaaata ttttaaatac gaggctatta ctctctttgg cctaccttcc caggtagttc
     2761 ttctatactc tttaagtcca cattgcagtc ctacaacccc gaggagtaaa ctcctcggtt
     2821 tgccctcctg ccgtttcgct cgccgctact aaggcaatcg cttttgcttt ctcttcctgc
     2881 agctacttag atgtttcagt tcactgcgtc ttcctcttca ctaccttaac agtagtgagt
     2941 gacaggcatt acctgccggg ttcccccatt cggacatccc tggatcattg cttacttaca
     3001 gctccccaag gcatttcgtc gttagtcacg tccttcatcg gcttctagtg ccaaggcatc
     3061 caccgtgcgc ccttattaac ttaaccttat aatcgtactc agactagaaa actagtgatt
     3121 tagacaaatc ctcttgtagt ccttagacta ctgcgatgat ttcctaaaat catacgtttt
     3181 ccttaacgtc ttcgtaactt gttttaacct aattttttca aaaattagaa aactcattaa
     3241 atattcacag cgttttcggt ttattttctt gttactattt ctatacgtac ttttacatac
     3301 gtttaggaat gtttgataga tattcaattt tcaatggaca aaatcttaac aacttccgtt
     3361 gttaatggag cctagcggga tcgaaccgct gacctcctgc gtgcaaagca ggcgctctcc
     3421 cagctgagct aaggccccac aagacctctc aaaattaaag aagactgacg tacaggtttc
     3481 catttcctta gaaaggaggt gatccagccg caccttccga tacggctacc ttgttacgac
     3541 ttcaccccaa tcatctatcc caccttaggc ggctggctcc taaaaggtta cctcaccgac
     3601 ttcgggtgtt acaaactctc gtggtgtgac gggcggtgtg tacaaggccc gggaacgtat
     3661 tcaccgcggc gtgctgatcc gcgattacta gcgattccga cttcatgtag gcgagttgca
     3721 gcctacaatc cgaactgaga ctggctttaa gagattagct tgccgtcacc gacttgcgac
     3781 tcgttgtacc agccattgta gcacgtgtgt agcccaggtc ataaggggca tgatgatttg
     3841 acgtcatccc caccttcctc cggtttatta ccggcagtct cgctagagtg cccaactgaa
     3901 tgatggcaac taacaatagg ggttgcgctc gttgcgggac ttaacccaac atctcacgac
     3961 acgagctgac gacaaccatg caccacctgt caccgatgct ccgaagagaa accctatctc
     4021 tagggcggtc atcgggatgt caagacctgg taaggttctt cgcgttgctt cgaattaaac
     4081 cacatgctcc accgcttgtg cgggcccccg tcaattcctt tgagtttcaa ccttgcggtc
     4141 gtactcccca ggcggagtgc ttaatgcgtt agctgcggca ctgagtcccg gaaaggaccc
     4201 aacacctagc actcatcgtt tacggcgtgg actaccaggg tatctaatcc tgttcgctcc
     4261 ccacgctttc gagcctcagc gtcagttaca gaccagagag ccgctttcgc caccggtgtt
     4321 cctccatata tctacgcatt tcaccgctac acatggaatt ccactctccc cttctgcact
     4381 caagtttgac agtttccaaa gcgtactatg gttaagccac agccttttac ttcagactta
     4441 tcaaaccgcc tgcgctcgct ttacgcccaa taaatccgga caacgctcgg gacctacgta
     4501 ttaccgcggc tgctggcacg tagttagccg tccctttctg gtaagatacc gtcaagtgag
     4561 aaactttcca ctcttctcac agttcttctc ttacaacaga gctttacgat ccgaaaacct
     4621 tcttcactca cgcggcgttg ctcggtcagg gttgccccca ttgccgaaga ttccctactg
     4681 ctgcctcccg taggagtctg ggccgtgtct cagtcccagt gtggccgatc accctctcag
     4741 gtcggctatg tatcgaagcc ttggtgagcc gttacctcac caactagcta atacaacgca
     4801 ggtccatctc atagtgaagc aattgctcct ttcaaatatc taccatgcgg taaatactgt
     4861 tatgcggtat tagctatcgt ttccaatagt tatcccccgc tatgaggcag gttacctacg
     4921 cgttactcac ccgttcgcaa ctcatccgtc tagtgcaagc accagacttc agcgttctac
     4981 ttgcatgtat taggcacgcc gccagcgttc gtcctgagcc aggatcaaac tctcataaaa
     5041 agttttgatt caaactcaag ctattgctag ctttccgttt tattgttttg ttttgtcatt
     5101 gacgatttat ctttagataa atcaccctgc acgtttggtt cgtcttcttt aattttcaaa
     5161 ggtcttgtcg ttatcgcgct ctcgcgacaa ctatcttagt ttatcatttc ttgtgaactt
     5221 tgtca
//
LOCUS       DBNFCO010000097         5176 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.097, whole genome shotgun sequence.
ACCESSION   DBNFCO010000097 DBNFCO010000000
VERSION     DBNFCO010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5176)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5176
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.097"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            66..761
                     /gene="liaF"
                     /locus_tag="AC1PIV_001759"
     CDS             66..761
                     /gene="liaF"
                     /locus_tag="AC1PIV_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012774984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein
                     LiaF"
                     /protein_id="HIP6612743.1"
                     /translation="MRKVQFFLLIESMIFTMAAFDVVANEASRTLLLFSALLLVIWYF
                     LGRKVNSVLLVSSLSLLFLVFVLNPFFIIGIMLLVVYMLINFFSRYEKRNQYTHIVFS
                     DYSLQVQKEKNRWFGNHDHSQDRFGFEDINIVRLFGNDVVDLDKTVLVGRDNIVVIRK
                     TFGRTKIIVPIDVEVALSATSIYGRVSFLGESYWDLRNESIAVNSPDYQESHKRVKVV
                     TNNILGDVEVVRV"
     gene            758..1774
                     /locus_tag="AC1PIV_001760"
     CDS             758..1774
                     /locus_tag="AC1PIV_001760"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIP6612744.1"
                     /translation="MRKRTYLLLAWFACLIVFVVIASTLPLLNYSLLDVTLWISTEQL
                     VFTLILLVIVLTLFLAVMVQTVSLASTQVMRTKLQAILKNKSIRTDTESDQLLLQLSD
                     KVRNLTRQVQLVDNQDLVKKEEIVEGERKRIARDLHDTVSQELFATSMILSGLSSNLS
                     TLPQETLQEQLMLVKDMIESAQRDLRILLLHLRPSELESKTLVEGFELILREVSDKSN
                     IIVHFQHEVEELPKLIEEHLFRIAQEIISNTLRHAKAKHLDVYLLQKETELQLKMTDD
                     GIGFQQGADDELSYGLQNIRERVEDMAGTIKIRTAPNKGVAIDIRIPLLKGKEDEYDS
                     SDAG"
     gene            1746..2387
                     /locus_tag="AC1PIV_001761"
     CDS             1746..2387
                     /locus_tag="AC1PIV_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HIP6612745.1"
                     /translation="MNTIRVMLVDDHEMVRLGLKSYLNLQPDVEVVAEASDGEEGLAK
                     ALEVKPDVVVMDLVMPKMTGVEATLALLKEWPQAQIVILTSYLDNEKIYPVLEAGARG
                     YMLKTSSADEILAAIRKVALGEYAIETEVEKKVEHHKRHPDLHDDLTAREREILTLLA
                     KGYDNQRIADESFISLKTVKTHVSNILSKLAVSDRTQAVVYAFQHGLVAQEDQ"
     gene            2437..3837
                     /locus_tag="AC1PIV_001762"
     CDS             2437..3837
                     /locus_tag="AC1PIV_001762"
                     /EC_number="3.1.3.-"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HIP6612746.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRVKNTGYIPESIQQVFKSLKE
                     KGILTGIASGRTPYGLVPEIKALKPDFFAMINGSYVEDAKGQVVYHQPMPQNLVESVL
                     NWAKEIGIEYGMLSSQKGTLSARTDRISQVIDLIYEGLETKPTFYKENDIYQLLTFEK
                     DGHEVELPEELQAELRSVRWDAISSDIVLKGSSKATGVAKVVEKLGLKPENVLVFGDG
                     LNDIELFDYAGISIAMGHSHPELQKHADYITKKVEEDGIFDALEKLGMVEKEKYFPQL
                     DLENVTGPVAHIKTNHGKLTVKLFPEIAPKTVANFVALSKDGYYDGIIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGTAFEDEFSMEAFNLRGALSMANAGPNTNGSQFFIVQNQNFP
                     YNAKELERGGWPKEVAEAYVKNGGTPYLDQRHTVFGHLVDEESFVVLDAIAAVATDSA
                     DCPHEDVVIETIEIED"
     gene            3839..4210
                     /locus_tag="AC1PIV_001763"
     CDS             3839..4210
                     /locus_tag="AC1PIV_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HIP6612747.1"
                     /translation="MKIGDKLKGTVTGIQPYGAFVQLENGTTGLIHISEIKTGFVDNI
                     YDHLKLGQEVLVQVVDFDEYTEKASLSIRTLEEEQQKIPCHHRFTNERNKIGFSPLAK
                     QLPKWIEEAKGYLKEHKEKKV"
     gene            complement(4236..5162)
                     /gene="cysK"
                     /locus_tag="AC1PIV_001764"
     CDS             complement(4236..5162)
                     /gene="cysK"
                     /locus_tag="AC1PIV_001764"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012774985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HIP6612748.1"
                     /translation="MAIYQNITQLVGKTPVIKLNNIVPEGAAEVYVKLEAFNPGSSVK
                     DRIALAMIEDAEKAGTIKPGDTIVEPTSGNTGIGLAWVGAAKGYNVIIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAKEIAEEKNGWVPFQFANPSNPKVHEDTTGQE
                     ILEDFGTTGLDAFVSGVGTGGTVSGVSHVLKTANPDIAIYAVEADESAVLSGEAPGPH
                     KIQGISAGFIPDTLDTSAYDGIIRVKSDDALATGRAIGGKEGFLVGISSGAAIHAAIE
                     VAKELGTGKKVLAILPDNGERYLSTALYEFND"
BASE COUNT         1606 a          975 c         1114 g         1481 t
ORIGIN      
        1 ttcctacttt ggatggagtt cttttactta ttttttgtta caatagtata gaaaggatgg
       61 agaagatgcg gaaagttcaa ttttttctac taatagaaag tatgattttt acgatggcag
      121 cctttgatgt ggtagccaat gaggccagtc ggaccctgct acttttctct gccttattac
      181 tcgtcatttg gtacttccta ggaagaaaag tcaacagtgt tttactggtc agctccttat
      241 ctctattatt tttggtcttt gttttaaatc ccttcttcat tattgggatt atgctactag
      301 tcgtgtacat gctgattaat ttcttttcac gttatgaaaa gagaaatcaa tatacccaca
      361 ttgtttttag tgactattct ctacaggttc aaaaagagaa aaatagatgg tttggcaacc
      421 acgaccactc tcaagatagg tttggttttg aagatattaa cattgtacgc ttgtttggca
      481 atgatgtagt tgatttggat aagactgtat tagttggcag agataatatt gttgtaattc
      541 gtaaaacgtt tggacggaca aaaattattg ttccaattga tgttgaggtt gcactttcag
      601 caactagtat ctatggacga gtaagtttcc tgggtgaatc atattgggat ttgcggaatg
      661 aaagtatagc ggtcaatagt cccgattatc aagaatcaca caaacgtgta aaagtcgtta
      721 ccaacaatat actgggagat gtggaggtgg ttcgcgtatg agaaaacgta cctacctact
      781 cctcgcctgg tttgcctgtc ttattgtttt tgtggtgatt gcttccaccc tcccactttt
      841 aaattattca ttgctagatg ttacgctctg gatttcaacg gagcagctcg tgtttactct
      901 cattctacta gttattgttt tgaccctttt tctagctgta atggtacaaa ctgtcagcct
      961 agcctccact caggttatgc ggacgaagtt acaagctatc ttgaagaata aaagtattcg
     1021 aacagatacc gaaagtgatc agctcttgct ccagttgtct gataaggtca gaaacctcac
     1081 gcgtcaggtg cagctggttg acaatcaaga tttagtcaag aaagaagaga ttgttgaggg
     1141 agaacggaaa cggattgcca gggatttgca tgatacggtt agtcaagagt tatttgcaac
     1201 gagcatgatt ttgtcaggat tatcgtccaa tctatccact cttccgcagg aaaccttgca
     1261 ggaacagctg atgctcgtga aagacatgat tgagtctgcc caaagagacc tacgcatcct
     1321 attattacat ctacgcccaa gtgaacttga aagtaaaacc ttggttgaag gatttgagtt
     1381 gattttgcgt gaagttagcg acaaaagtaa tattatcgtt catttccaac atgaagtaga
     1441 ggagttaccg aaactaattg aagaacatct cttccgcatt gcgcaagaaa ttatcagtaa
     1501 taccttgcga catgccaaag ccaagcattt ggatgtttac ctcttgcaga aggaaacaga
     1561 acttcagttg aaaatgacag acgatggtat cggcttccaa caaggtgcag atgatgaatt
     1621 aagttacggt cttcaaaaca tacgtgagcg ggttgaagac atggctggaa cgataaaaat
     1681 tcgcacagct ccaaataagg gagtggcgat cgatattcgt atcccactat tgaaaggaaa
     1741 agaagatgaa tacgattcga gtgatgctgg ttgacgacca tgagatggtt cgcctaggat
     1801 tgaaaagtta cttaaattta cagccagatg ttgaagtagt tgcagaagct agtgatggcg
     1861 aggaaggttt ggctaaagcg ttagaggtta aacctgatgt tgtagtgatg gacttggtta
     1921 tgcccaagat gactggcgta gaagcaactc tggccttgct gaaggaatgg ccgcaagcgc
     1981 agattgtcat cctgacctcc tatctagata atgagaaaat ctatcctgtg ctggaagcag
     2041 gagctcgtgg ctatatgttg aaaacgtcaa gtgctgacga aatcttagca gccatccgca
     2101 aggtagctct tggagaatat gctattgaga cagaagtaga gaaaaaagta gagcaccata
     2161 aacgccaccc agatttacat gatgacttga cagctcgtga acgcgaaatc ttgacgctgt
     2221 tagccaaggg atatgataat caacgaattg cagatgagtc cttcatatcc ttaaaaactg
     2281 ttaagaccca tgtttccaat atcttatcca aactagctgt tagcgatcgt actcaagcag
     2341 ttgtttatgc tttccagcat ggtttggtgg cgcaagagga ccaatagtgg tataatgaaa
     2401 attagttaat ttttaaccaa aggatagtgg aattatatgg atgcaaaact cagatataag
     2461 gcaaaaaaaa taaaaatagt cttttttgac attgacgaca cgctacgtgt gaagaataca
     2521 ggctacattc ctgaatcaat tcagcaggtt tttaaatcac tgaaagaaaa gggaattttg
     2581 acaggaattg cgtcaggacg aacgccttat ggtttggtgc cagaaatcaa ggccttaaag
     2641 ccagactttt tcgctatgat taacggctcc tacgtagaag atgccaaagg tcaggtagtg
     2701 taccatcagc cgatgcccca aaatttagta gaatctgtat taaattgggc taaagaaatt
     2761 ggaatcgaat atggtatgct tagtagtcaa aaagggacac tttctgcacg aactgaccgt
     2821 attagtcaag taattgactt gatttatgaa ggtttggaaa caaaaccaac tttttataaa
     2881 gaaaatgata tctatcaatt gttaactttc gagaaagatg gtcacgaagt agaacttcca
     2941 gaagagttgc aagcagaatt gcgtagtgtt cgttgggatg ctatttcatc ggacattgtg
     3001 ttaaaaggct cttccaaagc aactggtgtt gctaaggttg ttgaaaaact aggcctgaaa
     3061 cctgaaaatg tcctagtgtt cggagatgga ctcaacgata ttgagttatt cgattatgca
     3121 ggaattagta tcgctatggg gcattcgcat ccagaattgc aaaagcatgc agattatatc
     3181 acaaaaaaag tagaagaaga tggcattttt gatgccttgg agaaattagg tatggtagaa
     3241 aaagaaaaat atttcccgca attagatttg gaaaatgtta caggaccagt tgcgcatatc
     3301 aagactaacc atggtaagtt aacagtaaaa ctcttccctg aaattgcacc caaaactgta
     3361 gcaaatttcg tagctctttc taaagatggc tattatgacg gaattatctt ccatcgtatt
     3421 atcaaagact ttatgattca aggtggcgat ccaaccggaa caggtatggg tggtgaatct
     3481 atttatggta ctgcgtttga agatgaattt tcaatggaag cttttaatct cagaggagcc
     3541 ttgtcaatgg ccaatgcagg accaaataca aatggaagcc aattctttat cgttcaaaac
     3601 caaaacttcc catacaatgc gaaagaatta gaacgaggcg gttggcctaa agaagttgca
     3661 gaagcctatg tcaaaaatgg cgggacacca tatctggatc aacgccacac agtgtttggt
     3721 catctagttg atgaagaatc cttcgtcgtc ttggatgcta tcgcagcggt tgcaacagat
     3781 tcagcagatt gtccacatga agatgttgta attgagacca tcgaaataga ggattaagat
     3841 gaaaatcgga gataaactca aggggacggt aacgggtatt caaccgtatg gagcctttgt
     3901 acaattagag aatgggacga cgggcctaat ccatatctcg gaaatcaaaa caggttttgt
     3961 tgataatatt tatgatcatt taaaattggg gcaagaggtt ttggtacagg tagttgattt
     4021 tgatgaatat actgaaaagg ctagtttatc aatccggacc ttagaagaag aacaacaaaa
     4081 aattccgtgc catcatcgtt ttacaaatga acggaataaa attggttttt cccccttagc
     4141 aaaacaactt ccgaaatgga ttgaggaagc taaaggctat ctcaaagaac acaaagaaaa
     4201 gaaggtatag gatgcattcc taaccttctt tctttttaat cattgaactc ataaagagct
     4261 gttgacaagt aacgttctcc gttatcaggc aagattgcca acactttttt cccagttccc
     4321 aactccttag cgacttcgat agcagcgtga attgctgcac ctgaagaaat accaactaag
     4381 aatccttctt ttccaccgat agcacgacct gtagctaagg catcatcgga tttgacacga
     4441 ataatgccat cataggcgct agtgtccaaa gtatctggaa taaaacctgc cgaaatacct
     4501 tggatcttgt gcggaccagg tgcttcacca gataagacag ctgattcatc agcttcaaca
     4561 gcatagatag caatatctgg atttgctgtc ttcaaaacat gcgaaacacc tgaaacggta
     4621 ccaccagtac caacgccaga tacaaaggca tctaaaccag ttgtgccaaa gtcttccaaa
     4681 atttcctgtc ctgttgtatc ttcgtgaact tttggattgg atggattagc aaactggaaa
     4741 ggaacccagc catttttttc ttcagcaatc tcttttgctt tggcgatagc ccccttcatc
     4801 ccttcgctac caggagtcaa gacaagttca gctccataag cttggataat cttacgacgc
     4861 tcaacactca tggtttcagg catgacgata atcacattat aaccttttgc tgctccaacc
     4921 caagcaagac cgataccagt gttaccactt gttggctcaa caatagtatc tccaggtttg
     4981 attgtaccag ccttttcagc atcttcaatc atagccaagg cgatacggtc ttttacagaa
     5041 gatcctgggt taaaggcctc taatttcaca tagacctccg ctgccccctc tggaacgata
     5101 ttattgagtt taataacagg tgtttttcca actaattgag taatgttttg ataaatagcc
     5161 atatggcacc tccaaa
//
LOCUS       DBNFCO010000098         5147 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.098, whole genome shotgun sequence.
ACCESSION   DBNFCO010000098 DBNFCO010000000
VERSION     DBNFCO010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5147)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5147)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5147
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.098"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            <1..3151
                     /locus_tag="AC1PIV_001765"
     CDS             <1..3151
                     /locus_tag="AC1PIV_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="family 16 glycosylhydrolase"
                     /protein_id="HIP6612749.1"
                     /translation="ENFTIDKEQIITIKTPKNSKARYVRFRGTRVDDTPLRYSEIQIM
                     GRGKSYDESAPEYVPPKSEYDTLVWSDEFNGDKIDESKWQIIDGMWNHAAIYNRKAVS
                     IKKDGDKSYLSIRSTNHKDKKTLVEAVGHDRYDDKELPDKVTWSSGRLESKDKYSFQF
                     GRMAVRAKVNDSKGIWPAIWMLAQDETGHDEIDVLEYLGQNPWYAWTTNHFGILAKNK
                     KSDGSAYKNYEAWSQEFHVYEVEWTPDVIKWYIDGKFVFQTDRGKDRDGMHTRPMFPI
                     LETQVGDGWVGDVDYKRNMTKQDSEYLVDWVRIYQKADQSKVRFDNLDDAKPNDYVIK
                     PQQKLGHLVTVSNGKAAHENKNNFYYGGQPRYETSRLYADGDGENALVYKIANPEALH
                     LTTYYKTLEDYSVYNKEAGANEGKSVRKHLINAKDGEIDFTVYSSVDGKSWNKENVTV
                     VDNFVEATPAYARTTFDIRNIRKGTKFVKIVFPTVKGISYKLEDGTEKGLQASNVQLA
                     KVTFVATHPEAEPEKPIVDQEKLALSKVFSLDAGRKYFSVNQIKEIIDLISSYGYTDM
                     NLLLGNDGLRFLLDDMNLTVGDKVYDSEAVRKAIINGNKHYYDDPNGTTLSQSEMDDI
                     LAYAKEKNISIIPTINSPGHMDAIVEAMEELGIKSPKFSYNGKTSARTVDLKNDQAVA
                     FTKALIDKYASYFAGKSKIFNIGLDEYANDATNASGWHILQTQGDYGKFIQYANDLAA
                     IVKKHGLEPMAFNDGIYYNHDTSSGTFDKDIIASFWTGGWGGYDVASSKFLHEKGHKI
                     LNTNDAWYYVIGREAEGLGWYNLDQGLRGTKSTRFDQVPKSENTKVPIIGSMVAVWAD
                     DPSKPYSYDSIKKLLHSFTENNSDYFLAEYRDLREEVGKIPTDLNSYTPESVATLKEV
                     LNKIDWKLSRNNQAFVDGYLAEVKAAREALVPVTAKGDSVKAEPLPEGKLPLITAKGK
                     SVQAEPRPAFKGYLTSNYGPSVTPLSLVSKPSSEQSNSKQAASQKKELPNTGVVDGLG
                     FSLLGMIGLAFASRRRKKE"
     gene            complement(3442..3915)
                     /locus_tag="AC1PIV_001766"
     CDS             complement(3442..3915)
                     /locus_tag="AC1PIV_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HIP6612750.1"
                     /translation="MNKIESRHQLILSLIMEKKIHTQQELQELLEVNGVSVTQSTLSR
                     DIKMLNLVKVNEDDSSHYVINPIAPTRWEKRLRLYMEDALVMLKPIQHQVVLKTLPGL
                     ANSFGSILDAMEIPQIVATVCGDDVCLIICEDVEGAQACFEHLKQFTPPFFFSKL"
     gene            complement(3964..4992)
                     /gene="queA"
                     /locus_tag="AC1PIV_001767"
     CDS             complement(3964..4992)
                     /gene="queA"
                     /locus_tag="AC1PIV_001767"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HIP6612751.1"
                     /translation="MNTADFDFDLPEELIAQVPLEKRDSSKLLILDREKRSMVDSHFD
                     HIIDQLNPGDALVMNNTRVLPARLYGYKPETMGHVELLLLKNTQGDQWEVLAKPAKRL
                     KVGTTVAFGDGRLTATIVEELEHGGRIVEFSYEGIFLEVLESLGEMPLPPYIHEKLED
                     RERYQTVYAKENGSAAAPTAGLHFTQELLEKIEAKGVKLVYLTLHVGLGTFRPVSVDN
                     VDEHEMHSEFYNLSAEAAQTLNQVKDSGGRIVAVGTTSIRTLETIGNKFDGRLQADSG
                     WTNIFIKPGYTFRIVDAFSTNFHLPKSTLVMLVSAFAGREFTLDAYKHAVEERYRFFS
                     FGDAMFIQ"
BASE COUNT         1641 a          918 c         1131 g         1457 t
ORIGIN      
        1 tgaaaatttc accattgaca aggaacagat tataacaatt aaaactccga agaactctaa
       61 agcgcgttat gttcgcttta gaggtacgcg cgtagatgat actcctcttc gatattcaga
      121 aattcagatt atgggacgag gaaaatctta tgacgaatct gctccagaat atgttccacc
      181 aaaatctgaa tacgatacat tagtctggtc tgatgaattt aatggcgaca agattgatga
      241 aagtaaatgg caaattattg atggcatgtg gaatcatgcg gctatataca atcgtaaagc
      301 agtttctatc aaaaaagatg gcgacaagag ctatttgtct atccgtagca cgaaccataa
      361 ggataaaaaa actttggttg aagcagttgg gcacgatcgg tatgatgata aagaattacc
      421 agataaagta acatggtctt ctggtcgcct agaatctaaa gataagtatt ctttccaatt
      481 tggtcgaatg gctgttcgag ctaaggtaaa tgactctaag ggaatctggc ctgctatttg
      541 gatgttggca caggatgaga ccgggcatga cgaaattgac gttttggaat accttggtca
      601 aaatccatgg tatgcatgga caactaacca ttttggtatt ttggcaaaaa ataaaaaatc
      661 tgatggctca gcttataaga attacgaagc ttggagtcag gaattccatg tctacgaagt
      721 cgaatggact ccagatgtca tcaaatggta tattgatgga aaatttgttt ttcaaacaga
      781 ccgtggtaag gatcgggatg gtatgcacac ccgccctatg ttcccgatac tggaaaccca
      841 agttggtgat ggctgggttg gtgatgttga ttacaaacgc aacatgacta aacaggatag
      901 tgagtacttg gttgattggg ttcgaattta tcaaaaagca gatcaaagta aggtacgttt
      961 tgataatcta gatgatgcca agcctaatga ttatgttatt aagccgcagc aaaaacttgg
     1021 tcacctcgta acagtctcta acgggaaagc agctcatgaa aacaaaaata atttctacta
     1081 tggaggtcaa ccacgttacg aaacaagcag gctctatgct gatggtgatg gcgaaaatgc
     1141 actagtctac aagattgcta atccagaggc tttgcactta acgacttatt acaaaacact
     1201 tgaagactat tctgtctata ataaagaagc aggggctaat gaaggaaaat ctgttcgcaa
     1261 acatttgata aatgcaaaag acggtgaaat tgacttcact gtgtattcat ctgttgacgg
     1321 caaaagctgg aataaagaga atgttactgt agtggataat tttgtagaag caaccccagc
     1381 ttatgcacgc actacatttg atattcgcaa cattcgaaaa ggtactaaat ttgtgaagat
     1441 cgtctttcca acggttaaag gtatttccta taagttggaa gatggaacag agaaaggctt
     1501 gcaagccagt aatgtccagt tagcaaaagt aacttttgta gctactcatc ctgaagcaga
     1561 accagaaaaa cctattgttg atcaagaaaa actagccttg tccaaagttt tttcactcga
     1621 tgccggtcgc aagtatttct ctgtaaatca gataaaggag attattgatt taatttcttc
     1681 ttatggttac acggatatga acctcttatt gggaaatgat ggtctgagat ttttattaga
     1741 tgatatgaat ttgaccgttg gagataaggt gtatgacagt gaagcagtta gaaaagcaat
     1801 aataaatggt aataagcatt attatgacga tccaaacggt acaaccttaa gtcagagtga
     1861 gatggatgat attcttgctt atgctaagga aaaaaatatt tccattattc caactatcaa
     1921 tagcccaggt catatggatg cgattgtaga agcaatggaa gaattgggga taaaatcgcc
     1981 aaaatttagt tataatggca aaacatctgc acgtacagtt gatttaaaaa atgaccaagc
     2041 agttgctttt actaaagcct taattgataa atatgctagt tactttgcag gcaaatctaa
     2101 aattttcaat attggcttag atgagtatgc taacgatgct acaaatgctt ctggatggca
     2161 cattcttcag acacaaggtg attatggtaa gtttattcaa tatgccaatg atttagcagc
     2221 tatcgtcaag aagcatggtt tagagccaat ggctttcaat gatggtatct attataacca
     2281 cgatactagt tcgggtactt ttgataaaga cattattgct tctttctgga caggaggttg
     2341 gggaggatat gatgttgctt cctcaaaatt ccttcatgaa aaagggcata aaattcttaa
     2401 tacaaatgat gcttggtact atgttattgg acgtgaagca gaaggtttgg gatggtataa
     2461 ccttgatcaa ggtcttcgag gaactaaatc tacaaggttt gatcaagtac cgaaatctga
     2521 gaatactaag gtacccatta ttggtagtat ggttgcggta tgggcagatg acccaagcaa
     2581 gccttacagc tatgactcaa ttaaaaaact tttgcacagt tttacggaaa acaattctga
     2641 ttattttttg gcagagtacc gagatttgcg agaagaagtt gggaagattc ctactgattt
     2701 aaattcctat acaccagaga gcgtggcgac tttaaaagag gtcttgaaca agattgattg
     2761 gaaactaagt agaaataacc aagcgtttgt tgatggttac ttggcagaag taaaagcagc
     2821 gcgtgaagcg ttagttcctg tgacagcaaa gggagacagc gtcaaagcgg agcccttacc
     2881 agaaggcaag ctacctctga ttactgctaa aggaaaaagt gtccaagcag aaccacgccc
     2941 tgcctttaag ggatacctga catcaaacta tggaccatct gtcacacctt tatccctcgt
     3001 atcaaaacca agcagtgagc agtcaaattc caagcaagca gcttctcaga agaaagaatt
     3061 gccaaataca ggagtagtag atggtcttgg attctctctc cttgggatga ttggtctggc
     3121 atttgctagt cgccggcgga agaaggagta atgtagccac ttgaattaag gttcagggct
     3181 ttctaattgt aattatatag ttatctagtt tttctttcac tcgctttgct gtacccaagt
     3241 atagcatgta gcttattgcc ttgtacaaaa agtaaactag aaagctatga ataacaggat
     3301 aattttttat cggctactaa aaatcccccg taataaatct tattacggga gattttcgtt
     3361 tatgagtata aagggaagtt attgatattt atttgaaaaa ttatctttaa aattaagtat
     3421 gttgtttgtg aacacaaatt tttataattt actaaagaaa aatggtggag taaactgttt
     3481 caagtgctcg aagcaagctt gtgccccctc gacatcttca caaatgatga gacagacatc
     3541 gtcaccgcag acggtcgcta caatttgagg aatttccatg gcatccaaaa tagaaccgaa
     3601 tgagttggcc aatccaggta gggtcttgag caccacttga tgttggatag gttttagcat
     3661 gaccaaagca tcttccatat agagtcgcag tcgtttttcc cagcgagtag gagcaatggg
     3721 gttgatgaca tagtgagaag aatcatcttc gttgactttg acaagattga gcatcttgat
     3781 gtcacgggag agggtagatt gggtgacgga gactccgttg acctctagta attcttgcaa
     3841 ttcctgctgg gtatgtattt tcttctccat gattagagat aggatcagct gatggcggct
     3901 ttcaatcttg ttcatagggc cctccaataa aatcagaatt cagaataatt tggtgataac
     3961 agcctattga atgaacattg catccccaaa actaaagaag cggtagcgtt cttcaacagc
     4021 atgtttatag gcatctaagg taaattctct acctgcaaag gcagaaacta gcataaccaa
     4081 agtagatttt ggcaggtgga aattggttga gaaggcatca acgattcgga aggtgtagcc
     4141 aggtttgatg aagatatttg tccaaccaga atcagcttgc aaacggccat caaatttatt
     4201 accgatggtt tcgagggtgc ggatggatgt cgtgccgact gcgacgatac gaccaccgct
     4261 atctttgacc tgattgaggg tttgagcagc ttctgctgat aggttataga attccgagtg
     4321 catttcatgc tcatcaacgt tatcaacaga gactggtcgg aaggtcccaa gtccaacgtg
     4381 aagagtcaaa tagactagct tcactccttt agcttcgatt ttttcgagta actcttgggt
     4441 gaaatgtagt ccagcagttg gggctgcggc agaaccgttt tccttggcat aaactgtttg
     4501 atagcgttca cggtcttcta atttctcatg aatgtaaggt ggaagtggca tttcgcctag
     4561 actttccaag acttcaagga agataccttc ataggagaat tcaacaattc ttccaccgtg
     4621 ctctaattct tctacgatag tagcagttaa tcgtccgtca ccaaaagcga ctgtggtacc
     4681 gaccttcaga cgttttgctg gtttggcaag aacttcccac tgatcacctt gggtattttt
     4741 caaaagcaaa agctcaacat gtcccatagt ttcaggcttg tagccataga gacgggcagg
     4801 cagaacacgc gtattgttca tgaccagagc atcaccggga ttcaactggt cgatgatatg
     4861 gtcaaagtga ctgtcaacca tgctccgttt ttcgcggtcg aggatcaata gtttagagct
     4921 gtcgcgcttt tcaaggggta cttgagcgat aagctcttcg ggtaaatcaa aatcaaaatc
     4981 tgcagtattc atattcactc cttagactaa aataaaatat aggtaaaata aatcaatagg
     5041 gcaaatggca aagccaccaa tagaccacca atcaggtaga aaataaactt taggaccttt
     5101 gatttagaaa taaaatagcc agtaaggcag aacagaatac caataaa
//
LOCUS       DBNFCO010000099         5118 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.099, whole genome shotgun sequence.
ACCESSION   DBNFCO010000099 DBNFCO010000000
VERSION     DBNFCO010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5118)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5118)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5118
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.099"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(105..1478)
                     /gene="dnaA"
                     /locus_tag="AC1PIV_001768"
     CDS             complement(105..1478)
                     /gene="dnaA"
                     /locus_tag="AC1PIV_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HIP6612752.1"
                     /translation="MNQEQLFWQRFIELAKVNFKPSIYDFYVADAKLLGINQQVANIF
                     LNRPFKKDFWEKNFEELMIAASFESYGEPLTIQYQFTEDEQEIRNTTNTRSSIVHQVQ
                     TLEPATPQETFKPVHSDIKSQYTFANFVQGDNNHWAKAAALAVSDNLGELYNPLFIFG
                     GPGLGKTHILNAIGNKVLADNPQARIKYVSSETFINEFLEHLRLNDMESFKKTYRNLD
                     LLLIDDIQSLRNKATTQEEFFHTFNALHEKNKQIVLTSDRNPDHLDNLEERLVTRFKW
                     GLTSEITPPDFETRIAILRNKCENLPYNFTNETLSYLAGQFDSNVRDLEGALKDIHLI
                     ATMRQLSEISVEVAAEAIRSRKQTNPQNMVIPIEKIQTEVGNFYGVSLKELKGSKRVQ
                     HIVHARQVAMFLAREMTDNSLPKIGKEFGNRDHTTVMHAYNKIKTLLLDDENLEIEIT
                     SIKNKLR"
     gene            complement(1681..2445)
                     /locus_tag="AC1PIV_001769"
     CDS             complement(1681..2445)
                     /locus_tag="AC1PIV_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HIP6612753.1"
                     /translation="MEELRTLNISEIHPNPYQPRIHFDEKELLELAQSIKENGLIQPI
                     IVRKSSIIGYELLAGERRLRASQLAGLTTIPAVVKELTDDDLLYQAIIENLQRSNLNP
                     IEEAASYQKLISRGLTHDEVAQIMGKSRPYISNLLRLLNLSSQTKQAVEEGKISQGHA
                     RQLVSFSEEKQAEWVQLILSKDLSVRTLEKLIAANKKKHTKLKQRDQFLKEQEDSLSK
                     TLGTATKIIKKKNGSGEIRISFNDLDEFERIINNFK"
     gene            complement(2506..3702)
                     /locus_tag="AC1PIV_001770"
     CDS             complement(2506..3702)
                     /locus_tag="AC1PIV_001770"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S1C family serine protease"
                     /protein_id="HIP6612754.1"
                     /translation="MERIPYMKKYLKFAILFVIGFFGGLIGALSASFFQPQVQQANSA
                     ITSVSNVQYNNETSTTKAVEKVQNAVVSVINYQKSANNSLGVIFGNIESSDELAVAGE
                     GSGVIYKKYGQYAYIVTNTHVINNAEKIDILLASGEKISGELVGSDTYSDIAVIKISA
                     DKVTAVAEFADSDTIKVGETAIAIGSPLGSVYANTVTQGIISSLSRTVTSQSKDGQTI
                     STNAIQTDTAINPGNSGGPLINTQGQVIGITSSKITSSSANSSGVAVEGLGFAIPAND
                     AVAIINQLEKTGQVSRPALGVHMVNLTTLSTSQLEKAGLSNTELTSGVVIVSTQSGLP
                     ADGKLETFDVITEIDGEAIQNKSDLQSALYKHQIGDTITVTYYRNNQKQTVDIKLTHS
                     TEELSE"
     gene            3876..4355
                     /gene="rlmH"
                     /locus_tag="AC1PIV_001771"
     CDS             3876..4355
                     /gene="rlmH"
                     /locus_tag="AC1PIV_001771"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HIP6612755.1"
                     /translation="MKIKLITVGKLKEKYLKEGIAEYSKRLGRFTKLDMIELPDEKTP
                     DKASQAENEQILKKEADRIMSKIGERDFVIALAIEGKQFPSEEFSQRISDIAVNGYSD
                     ITFIIGGSLGLDSCIKKRANLLMSFGQLTLPHQLMKLVLIEQIYRAFMIQQGSPYHK"
     gene            4380..5063
                     /locus_tag="AC1PIV_001772"
     CDS             4380..5063
                     /locus_tag="AC1PIV_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family protein"
                     /protein_id="HIP6612756.1"
                     /translation="MNQKEYRVFEGLRIACSLTFISGYLNAFTFVTQGGRFAGVQSGN
                     VISLAYFLAKGDFAQVVNFSIPILFFVFGQFFTYLARRYFEKQTWSWHFGSSVMMLVL
                     ILLTIILSPIMPASFTIASLAFVASIQVETFRRLRGAPYANVMMTGNVKNAAYLWFKG
                     VIEKDSELRKTGRNILLTIIGFMLGVIISTHLSFQFEEYALIGLILPVLYINYELWQE
                     KRPTRGRSK"
BASE COUNT         1518 a          890 c          945 g         1765 t
ORIGIN      
        1 gtgtattctg tggaaaagtg atgaaagacc aataaaactg cggaaattaa cttgttcaca
       61 acttgtggaa aaaaacagag ttttttaaaa aagttataca caggttaacg aagtttattt
      121 tttatactgg taatctctat ttctaaattc tcatcatcca agaggagagt ttttatttta
      181 ttgtatgcat gcataacggt tgtatggtct cgattaccaa attctttccc aatttttgga
      241 agggaattgt ctgtcatttc acgtgctaaa aacatagcaa cttgtcgcgc gtgaacgata
      301 tgttgaacac gcttagaacc ttttaattct ttcaagctga caccgtagaa atttcccact
      361 tcggtttgga ttttctcaat aggaataacc atgttttgtg gatttgtttg ttttcttgat
      421 cgaatagcct cagcagcaac ctcgacactt atctcagaca gttgacgcat agtggctatc
      481 aaatggatat cttttaaggc accttcaagg tcacgtacgt tcgaatcaaa ttgcccagct
      541 agataggata gcgtctcatt tgtaaagttg taaggcaggt tctcgcactt gttacgtaaa
      601 attgcgatac gtgtttcaaa atcaggtgga gtgatttcac tggttaaccc ccatttgaaa
      661 cgtgttacta gtctttcttc caaattgtct aagtgatcgg gattacggtc gcttgtgagt
      721 acaatctgct tatttttttc atgaagcgca ttaaaagtat ggaaaaattc ttcctgtgtt
      781 gttgctttat tacggagaga ctgaatgtca tcaattagaa gtaagtccag attgcgatag
      841 gtttttttga aactttccat atcattgaga cggaggtgtt ctaaaaattc attgatgaat
      901 gtttccgatg agacatattt tatccttgcc tggggattat cggctagaac cttatttcca
      961 atcgcattta aaatatgagt ttttccaaga ccaggaccac caaaaatgaa taatggattg
     1021 tagagctcac ctaggttatc agatacagct aaagctgcag cctttgccca gtgattattg
     1081 tctccttgta caaaattagc aaaggtgtac tgggatttta tatcagaatg aaccggttta
     1141 aaagtttctt gaggagtagc cggctcaagt gtctgtacct ggtgaactat tgaacttctt
     1201 gtgtttgtag tattcctaat ctcctgttca tcctctgtaa attgatattg gatggtaaga
     1261 ggctctccgt agctttcaaa actagcggca atcattaact cttcgaagtt tttttcccag
     1321 aaatcttttt taaatggacg atttaagaaa atattggcaa cttgctggtt gattccgagt
     1381 aattttgcat cagcgacata aaaatcataa atagatggct taaaatttac ctttgccaat
     1441 tcaataaatc gttgccaaaa aagttgttct tggttcatat tttccccctt tcacattata
     1501 ttcgttagaa tagtgtacca taaaaaacaa aagttttcca cagataattt ttaaaatcca
     1561 cactgttaag aaaagttttc cacaagatgt gaataaaagt cagaaccctt gctggtcctg
     1621 actttttgta atgattttag tgtggaaaag agtgtttata aaaataaatt gtaaacaagt
     1681 ctatttaaaa ttgttgataa ttctttcgaa ttcatcgagg tcattaaagc taatccgaat
     1741 ttctccgctc ccgtttttct tcttgataat ttttgtagct gttccaagag ttttactgag
     1801 tgaatcttcc tgttctttta aaaattggtc gcgttgttta agcttagtgt gttttttctt
     1861 atttgcagct attaattttt caagcgtacg cacacttaaa tcctttgata aaatgagttg
     1921 aacccattcg gcttgctttt cttctgaaaa tgacaccaat tgtcgcgcgt gcccttgtga
     1981 aatttttcct tcttctacag cttgtttagt ctgagatgat agatttagta ggcgcaataa
     2041 attactgata tatggtcttg attttcccat gatttgagca acttcatcat gtgttaaccc
     2101 tctactaatc aatttttgat aagaggctgc ttcttctatc ggatttaagt tagaacgctg
     2161 cagattctct atgatagcct gatagagtaa atcatcatca gtcagttctt ttaccactgc
     2221 tggtattgta gtcagtccag ctaattgact ggctcgcaac cttctttctc cagctaataa
     2281 ttcgtatccg ataatagaag attttcttac aataatcggt tgaattaagc cattttcctt
     2341 aatagattga gcgagctcaa gtagctcctt ttcatcaaaa tgaattcttg gctgataggg
     2401 attgggatgg atttctgaaa tatttagtgt acgtaattct tccatatatc cttattctag
     2461 caaaaaaaat gagactttac aattgtgtaa agtctcattt gtcaattatt cgctaagttc
     2521 ttctgtagaa tgtgtcaact taatgtcaac agtttgtttc tgattattgc ggtaataagt
     2581 tacagtgatt gtatctccaa tttgatgttt gtagagagcg ctctggaggt cactcttatt
     2641 ttgaatagct tctccgtcaa tctcagtaat aacatcaaaa gtttctaatt ttccatctgc
     2701 aggtagccca ctttgtgtag agacaattac tacaccggat gttaattccg tatttgataa
     2761 tccagctttt tctaattgac tagttgacaa ggtcgtcaag ttaaccatat gaactccaag
     2821 agcaggtcgg ctaacttgtc cagttttttc aagctgattg ataatagcta cggcatcatt
     2881 tgcaggaata gcaaatccca acccttctac agccacgcct gagctatttg cagaacttga
     2941 ggtaattttg ctagaggtaa tgcctatcac ttgtccttgg gtattgatta acggtccgcc
     3001 agagtttcca gggttgatag ctgtatcagt ttgaatagcg ttagttgaga ttgtttgtcc
     3061 atcttttgat tgtgaagtaa ctgtccgact taagctagaa ataataccct gggtaactgt
     3121 attggcgtag acgctaccta gaggactacc aattgcgata gcagtttctc caactttaat
     3181 tgtatcggaa tcagcaaatt cagcaacagc agtgacttta tctgctgata tttttataac
     3241 agctatatca gaatatgtat cggaaccaac aagttcaccg ctaatttttt ctccagatgc
     3301 taaaaggata tcaatctttt ctgcgttatt aataacatgc gtatttgtca caatataggc
     3361 atattgacca tattttttat agataacccc agacccctct ccagcaacag ctagttcgtc
     3421 agatgattca atatttccaa agataacacc aagactattg ttggctgatt tttggtaatt
     3481 aataacagac acaacagcat tttgtacttt ctctacagct tttgtggtgg aagtttcatt
     3541 attatattga acattgctga cactagtgat agcagaattt gcttgttgca cctgtggctg
     3601 gaagaaagag gctgacaagg ccccgataag acccccaaaa aatccaatta caaataaaat
     3661 cgcaaatttc aaatattttt tcatataagg aatcctttcc atttctttaa ttttccttaa
     3721 gagtactatt tctttcttaa ttataactta aagttttcaa aaatcaatcc acaacctgtg
     3781 gataactctg tgaattatgt gaaaaactgt agccatatcc tgattttcta aaaatatttt
     3841 ctgtcgtatg cttgtggata tgttacaatt attttatgaa aataaaattg attaccgttg
     3901 gaaaattgaa agaaaagtac ctcaaagaag gtattgcaga atatagtaaa cgattgggac
     3961 gatttactaa gttggatatg attgagcttc ctgatgaaaa aacaccagat aaagccagtc
     4021 aggcagagaa tgaacaaata ttaaaaaaag aagccgatag aattatgtct aaaattggag
     4081 agcgagattt tgtcattgcc ttagcgatag aagggaaaca atttccatcg gaagaattta
     4141 gtcaaaggat atctgacatt gcagtaaatg ggtattcaga tataactttt atcatcggtg
     4201 gtagtttggg tctcgattct tgtattaaaa aaagagctaa tttgttgatg agttttggac
     4261 agttgacact tccccatcaa ctaatgaaat tagttctcat cgagcagatt tatcgtgcat
     4321 ttatgattca gcagggaagc ccatatcata agtagtttca cgtgaaacaa ggagtgaaaa
     4381 tgaatcaaaa agagtatcgt gtttttgagg gattgagaat tgcttgttca ttaacgttta
     4441 tcagtggtta tttaaatgcc tttacttttg tgactcaggg tggtcgcttt gctggcgtac
     4501 aatctggaaa tgttatttcc ctagcttatt ttttagctaa aggtgatttt gcgcaggtag
     4561 ttaatttttc cattcccatt ttattttttg tattcggaca attttttacc tacttagcaa
     4621 gaaggtattt tgaaaaacaa acatggtctt ggcactttgg tagtagtgta atgatgttag
     4681 ttcttatttt actaactatc attctctcac ctataatgcc tgcgtctttt acaattgcta
     4741 gtctagcctt cgtagcctct attcaagtag aaacatttag aaggttacga ggtgctccgt
     4801 atgccaatgt gatgatgaca gggaatgtca aaaatgctgc ttatctctgg tttaaaggag
     4861 ttattgaaaa agattcagaa cttagaaaaa caggtagaaa catcttattg accattatag
     4921 ggtttatgct aggtgtcatc atatctactc acctatcctt ccaatttgaa gaatatgccc
     4981 ttattggtct gattttgcca gtgttatata ttaattatga attatggcaa gaaaaaagac
     5041 ctactcgagg taggtctaaa tgattccagc aggattcgaa cctgcgaccg ttcgcttaga
     5101 aggcgaatgc tctatcca
//
LOCUS       DBNFCO010000100         5072 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.100, whole genome shotgun sequence.
ACCESSION   DBNFCO010000100 DBNFCO010000000
VERSION     DBNFCO010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5072)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5072)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5072
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.100"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(<1..727)
                     /locus_tag="AC1PIV_001773"
     CDS             complement(<1..727)
                     /locus_tag="AC1PIV_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HIP6612757.1"
                     /translation="MKLIKQLIHILISIGLIGSFFLYAHLIQNELGSTKNDGTIEIIA
                     EQPNQVIDSIQINGRYIHSSEIIENQWGINDADLIPNFSSLGEENSLVIKSSSSVRTL
                     SFEYFVSENPTIVKIKVGGQLVESIDTSTGDKYKNLAFIELPYTLRITKDNQFWYLHL
                     IVLALGLTCFILNGATWRIKRRDIRILTILLIVQYIFTTFTFPRLYRNELVLFNSNFN
                     KMETQQLLVALTYLIFFSLLGYKQ"
     gene            941..2089
                     /gene="cps2T"
                     /locus_tag="AC1PIV_001774"
                     /gene_synonym="wchF"
     CDS             941..2089
                     /gene="cps2T"
                     /locus_tag="AC1PIV_001774"
                     /gene_synonym="wchF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta 1-4 rhamnosyltransferase Cps2T"
                     /protein_id="HIP6612758.1"
                     /translation="MKHVFIIGSRGLPAKYGGFETFVQQLVSHQQSEKICYHVACLSD
                     TSHHQHSTYLGADCFTINPPKLGPARVIAYDMMAITYALKIIKEQQIERPIFYILGNT
                     IGGFIVPFAKQIHSVGGTLFVNPDGLEWKRAKWAKPVQRYLKFSEKMMVKYADLIIAD
                     NEGIEDYIQSEYSATNTRFIAYGTDLSPTKLTKESEQVRQYFTNWNIKEKEFYLIIGR
                     FVPENNYVTAIREFMASNTRRDLVIVANHEGSAYFQKLKDETGFISDKRIKFVGTVYD
                     QELLKYLRQECRAYIHGHEVGGTNPSLLEALAQTNENLVLGVDFNRKVALEGARYWSK
                     ESGSLSQLINQIDENAEAMELGEIAKKHMKDEYTWEKIVQEYEELFLQ"
     gene            2086..3015
                     /locus_tag="AC1PIV_001775"
     CDS             2086..3015
                     /locus_tag="AC1PIV_001775"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002933134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HIP6612759.1"
                     /translation="MKVNILMSTYNGQQFLAEQIRSIQEQSYIDWTLFIRDDGSSDRT
                     REIIKDFVEQDQRIHFIDVETDENLGVIKSFHRLVHYDTADFYFFSDQDDVWLPNKLE
                     VSLKKAQAYPTNLPLMVYMDLKVVNQNLEVMAESMVKSQSHHANTELVQELTENTVTG
                     GVAMINHHLAEMWQVTEDILMHDWYLALLASALGKLVFIDKPGELYRQHSDNVLGART
                     LSKRFKKWIRPHILFAVYWDLIKNSQKQARHLLQMPLSQSNRELIEAFVTIMDKPMLE
                     RFRILRKYGLRKNKTFHTLVFTTLIVTKFAYKE"
     gene            3018..3824
                     /locus_tag="AC1PIV_001776"
     CDS             3018..3824
                     /locus_tag="AC1PIV_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIP6612760.1"
                     /translation="MNLLNKENQILLREMIKTDFKLRYQGSLIGHLWSILKPMLLFTI
                     MYLVFVRFLRFDDGTPHYAVGLLLGMVTWNFFTEATNMGMMSIVSRGDLLRKLNFSKE
                     IIVFSSVAGAAINYAINLMVVFVFAAINGVPFTWSVLVIIPLFFELALLATGIAFILS
                     SLFVRFRDIGPIWEVFLQAGLYATPIIYSLTFILQRGQVTFAKLMMLNPVAQIIQDLR
                     HFIVYSGNTTVSELIENPVIVAIPYILPVVVYLLGITVFRKNAKKFAEIL"
     gene            3824..5038
                     /locus_tag="AC1PIV_001777"
     CDS             3824..5038
                     /locus_tag="AC1PIV_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIP6612761.1"
                     /translation="MVKNNNIAVKVEHVSKSFKLPTESSQSLRTTLVNLFKGIKGYVE
                     YNVLQDISFEVEKGDFFGIVGRNGSGKSTLLKILSQIYVPERGTVAVDGKLVSFIELG
                     VGFNPELTGKENVYLNGAMLGFTAEEIDAMYDDIVEFAELSEFMNQKLKNYSSGMQVR
                     LAFSVAIKAQGDILILDEVLAVGDEAFQRKCNDYFLERKKSGKTTILVTHDMGAVKKY
                     CNKALLIEKGYVKALGEPDDVANQYSFDNVLASISEVTENEEPLHQSDIVKDLQINLV
                     SKNQIEPDESIEIEFRYTVLEDIETHVAFTFLDLERHFDVYNDNSMDLKTFGKGEKFF
                     RVKCKLPSINQAKLKMAVSVRNSNKQPLLFAKTSDTPAIFISRKFSTDNIAEEDAATG
                     FIQRNSQWELLD"
BASE COUNT         1653 a          753 c         1026 g         1640 t
ORIGIN      
        1 gttgtttgta tcccaaaaga ctaaaaaata taaggtaagt cagtgcaact aatagctgtt
       61 gagtttccat tttattaaag ttcgaattaa atagcactaa ttcattgcga tataaacgtg
      121 gaaatgtaaa agtagtgaat atatattgaa cgattaataa tattgttaag atacggatat
      181 ctcttctttt gattctccat gttgctccat ttaagataaa gcatgttaga cctaaagcaa
      241 ggactattaa gtggaggtac caaaattgat tatctttagt tatccgtaaa gtatagggaa
      301 gctcaataaa ggctaaattt ttatatttat ctccagttga tgtgtcaatg gattcaacca
      361 attgtccacc gactttaatt tttacaatag tcggattttc actaacaaag tattcaaatg
      421 ataaggttct tacagaagag gaagatttaa ttacgagtga attttcctca cctagagaag
      481 aaaaattggg aattaaatca gcgtcattga ttccccattg gttttctata atttctgatg
      541 aatgaatata acgtccattt atttggatgc tgtcgattac ttggtttggt tgttctgcga
      601 ttatttctat agttccatca ttttttgtag aacctaattc gttttgaatg aggtgtgcat
      661 agagaaaaaa acttccaatc aatccgatgg agattagtat gtgaataagc tgtttgatta
      721 atttcatatt tattaacaat tctaagtttt atatttttat gtaaaagcca gtacatatta
      781 tatcaaattt ttcttattaa ctcaaaattt gtttttatct atactgtgga gtcagaggcg
      841 tagaaaaaga aaagccttta taaccaaact aggatagaat taggaaaaaa aactaaaaaa
      901 tggtataatg aaaagaactg caatttgatg gagaggattc atgaaacacg tttttattat
      961 cggtagtcgt ggactgccag caaaatatgg tggctttgag acctttgtcc aacaattggt
     1021 cagtcaccag caatctgaga agatttgtta tcatgtggct tgtttatcgg atacaagtca
     1081 tcaccaacat tcgacctacc tgggtgcaga ttgcttcaca attaatccac caaaacttgg
     1141 accggctcgt gtgattgctt atgatatgat ggcgatcact tatgccctta aaatcattaa
     1201 ggaacagcag atagagcgac caattttcta tatcttggga aataccatag gtggcttcat
     1261 agtacctttt gcgaaacaga ttcactctgt tggaggtacc ttgtttgtca atccagatgg
     1321 tttggaatgg aaacgggcca agtgggctaa gccagtccaa aggtatctaa aattttctga
     1381 aaaaatgatg gtcaaatatg ctgatttgat tattgctgat aatgagggaa ttgaggatta
     1441 tattcaatct gaatactcgg ctaccaatac acgctttatt gcctatggta cagatttaag
     1501 tccgactaag ttaacaaaag aatctgagca agttcgccaa tattttacaa attggaacat
     1561 taaagagaaa gaattttatc tgattattgg tcgttttgta cctgagaata actatgtgac
     1621 agcaattagg gagtttatgg caagtaacac gagacgtgat ttagtcatcg ttgcaaacca
     1681 tgaaggctct gcctattttc aaaaattgaa agatgagaca ggctttatat ccgataagcg
     1741 gattaagttc gtaggaacag tatatgacca agaactactt aagtatctgc gccaagaatg
     1801 tcgagcttat attcatgggc atgaagttgg aggaaccaat cctagtctcc tagaagcgct
     1861 ggcgcaaacc aatgaaaatt tggttttagg tgttgatttt aaccgcaaag ttgccctaga
     1921 aggtgctcgg tattggagta aggagtcagg tagcctgagt caattaatta accaaattga
     1981 tgagaatgct gaagcgatgg aattaggaga aattgcgaaa aaacacatga aggatgaata
     2041 cacctgggaa aaaatcgtcc aagagtacga ggaattattt ttacaatgaa agtaaatata
     2101 ctcatgtcga cctacaatgg tcaacagttc ttagctgagc aaattcgctc tatccaagaa
     2161 cagtcataca tagactggac actattcatt cgtgatgatg gttccagtga tcgaactaga
     2221 gagattatta aagattttgt tgaacaagat cagcgaattc acttcataga tgttgagaca
     2281 gacgaaaatc tcggtgtcat caaaagtttt cataggctag ttcattatga tactgctgat
     2341 ttctattttt tcagtgacca agatgatgtt tggctaccaa ataaactgga agttagcctg
     2401 aaaaaagcac aagcctatcc aacaaatttg ccattgatgg tttatatgga cctcaaagtt
     2461 gtcaatcaaa atctagaagt tatggcagaa agcatggtaa aatctcaatc tcatcatgcc
     2521 aatacggaat tggtgcaaga gttgactgag aatactgtaa ctggcggtgt cgccatgatt
     2581 aatcatcatc ttgctgaaat gtggcaagta actgaggata ttttgatgca tgactggtat
     2641 ttagctttgt tggcctcggc tttgggtaaa ctggttttta ttgacaagcc tggcgaactc
     2701 tatcgccagc attctgataa tgttttaggg gctcgaacac tctcaaaacg ctttaaaaaa
     2761 tggattcgcc ctcatatttt atttgcagtt tattgggact tgattaaaaa tagtcaaaaa
     2821 caagcccggc atttattaca aatgcccctt tctcaatcaa atagagaatt aatagaagcc
     2881 tttgtaacca ttatggataa accaatgctt gaacgattca ggattttgag aaaatatggt
     2941 ttaagaaaaa acaaaacctt ccatacatta gtattcacaa cactgattgt gacaaaattt
     3001 gcatataagg aatagttatg aatttattaa ataaagaaaa tcaaatactc ttaagagaga
     3061 tgattaaaac agattttaaa ttacgttacc aaggttctct cattgggcat ctctggtcga
     3121 ttttgaaacc gatgttactt tttacaatta tgtatttagt atttgttcgt tttttgcgct
     3181 ttgatgatgg aactcctcat tatgcagtag ggctactatt gggtatggta acatggaact
     3241 tttttacaga agcaactaat atggggatga tgtctattgt ttcacgcgga gatttgttgc
     3301 gtaaattgaa tttttcgaaa gaaattattg tcttttcttc agttgcagga gctgcaatta
     3361 attacgccat taacttaatg gttgtgtttg tatttgctgc tattaacggg gttcccttta
     3421 cttggtccgt tttagttata atcccattgt tttttgaatt ggcgttacta gcaacaggta
     3481 tagctttcat tctatcttcc ttatttgtaa gatttagaga tattggtcca atttgggaag
     3541 tgttcttaca ggctggattg tatgcgacac caattattta ttcattgaca tttattttac
     3601 agcgtgggca agtaacattt gctaagttga tgatgttgaa ccctgttgca caaattattc
     3661 aagacttgag acattttatt gtttattctg ggaatactac agttagtgaa ttgatagaaa
     3721 atcctgttat tgtggcaatt ccgtatattc ttccagtcgt tgtttaccta ttgggtataa
     3781 ctgtgtttag aaaaaatgcc aaaaagtttg cggagatttt gtaatggtaa aaaataataa
     3841 tattgctgta aaagtagaac atgttagcaa gagttttaag cttccaacgg agagtagtca
     3901 gagtctaaga actactttag ttaatttatt taaagggatt aaaggctacg tagagtataa
     3961 tgttttgcag gatatcagtt ttgaagttga aaaaggggac ttttttggaa ttgttggtcg
     4021 caatggttct ggtaagtcga cactgttaaa aattttatct caaatatatg ttcctgaaag
     4081 agggactgta gctgtggatg gtaaattagt ttcttttatt gaacttggtg ttgggtttaa
     4141 tccggaacta actggtaagg aaaatgtata cctaaacggt gcgatgttag gatttactgc
     4201 agaagaaatt gatgcaatgt atgatgatat tgttgaattt gcggaattga gtgaattcat
     4261 gaatcaaaag ttgaaaaact attctagtgg tatgcaggta cgtttagcct tttcagttgc
     4321 cattaaagct caaggagata ttctgatact tgatgaggtt ctagcagtcg gtgatgaggc
     4381 ctttcagcgt aaatgtaatg attacttcct agagcgtaaa aaaagtggaa aaacaaccat
     4441 tcttgtcacc catgatatgg gagctgtgaa aaagtattgt aataaagctc ttcttataga
     4501 gaaaggatac gtcaaggcat taggagaacc tgatgatgta gctaatcaat acagttttga
     4561 taatgtgctt gcctcaataa gcgaagttac agaaaacgaa gaacctctgc atcagagtga
     4621 tattgtaaaa gatttgcaga ttaacctggt ctcaaaaaat caaattgaac cagatgaatc
     4681 aattgaaatc gagtttagat atacggtttt agaagatatt gaaacacatg ttgcatttac
     4741 atttttagat ttagaacgtc attttgatgt atataacgac aattctatgg atttaaaaac
     4801 atttggtaaa ggcgagaagt ttttccgagt gaaatgtaag ctaccttcaa ttaatcaggc
     4861 aaaattaaaa atggcggtgt cagtacgaaa tagtaataag cagccgttat tatttgccaa
     4921 gacatctgac acaccggcta tttttattag taggaagttt agtactgata atattgcaga
     4981 ggaagacgca gcaaccgggt ttattcagag aaatagccaa tgggagctgc tagattaata
     5041 aaatataacg gaggcagaat gtcgcgtttg tt
//
LOCUS       DBNFCO010000101         4963 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.101, whole genome shotgun sequence.
ACCESSION   DBNFCO010000101 DBNFCO010000000
VERSION     DBNFCO010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4963)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4963)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4963
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.101"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(167..964)
                     /locus_tag="AC1PIV_001778"
     CDS             complement(167..964)
                     /locus_tag="AC1PIV_001778"
                     /EC_number="3.6.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HIP6612762.1"
                     /translation="MNQISISNLEFSYHPDKKILKGLNIILDERSTAIIGQNGAGKTT
                     FVKLLKGLIRPTAGKIMLNGQDLSEQSVAKIAKSIGLIFQNPDDQIFKHTVLDEIMFG
                     PLQMGMTHSQAEQAARKTMSLLGLDGFDKVNPYDLGLSDRKMVSIAAIVAMDTQVVIF
                     DEPTIAQDDAGKKQIQSVIQLLREQGKIVISILHDMDFVAETFERALVFAQGEVLLDG
                     SVREVFSQKDVLEKAYLSQPTTMQLCQALGYDDVFLTPEEFIAYKQE"
     gene            complement(961..1815)
                     /locus_tag="AC1PIV_001779"
     CDS             complement(961..1815)
                     /locus_tag="AC1PIV_001779"
                     /EC_number="3.6.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HIP6612763.1"
                     /translation="MAHIKIENLKYQYPFAEKLALDGITCEIRPGEFIGVIGRNGSGK
                     STFCQSLTGLVPNFYRGSYGGKVWIDQSEVKRVEVDDLCQKVGSVFQNPFNQITGSKA
                     TVYEEIAFGLENFGVPKEEMEVRIEESLRLLDIEEYRDRAPFDLSGGQMQRMAIASIM
                     AMKPEVIILDEPTSQLDPQGSEAVFKAIQSLSKQGITVIMVEHKVEKIAAYSDRVMLL
                     DQGKLIAMDTPQAVFSRPDLEKYGVVAPTFTRICKQLGMKLPGSSYYPVTLEEASQLL
                     AKNRGGNV"
     gene            complement(1815..2579)
                     /locus_tag="AC1PIV_001780"
     CDS             complement(1815..2579)
                     /locus_tag="AC1PIV_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     component T"
                     /protein_id="HIP6612764.1"
                     /translation="MKTMSLFEDKNSFLNNLSPLTKMLYVLATILIPIIAGDLAVFSI
                     TILLSVVLLAHSKVLRQTLPILSVSGFVILTVGIIQGLFRSGNVTPVFQLGPVIFYKE
                     GLIFAAEIALNVCNIILAFCVLILTTKSSDMIEELVRKGFSPRMGYVFVSLFQLIPQM
                     TSRMATITDAQRSRGMETEGSMLVRLKAFLPLVSPVIMSSFIDTRERAIALEVRGFNS
                     KSKKTFINPPIRSQFDRLIQIFCIFGVVLAIVWRVL"
     gene            complement(2590..3171)
                     /locus_tag="AC1PIV_001781"
     CDS             complement(2590..3171)
                     /locus_tag="AC1PIV_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HIP6612765.1"
                     /translation="MKFNTAALVLIPAGVGINYIGKLIAGVLKLPLWLDSIGTCLSAC
                     LAGPIVGAVVGIMNNLIYGLTVDPISTVYALTNAALGIAVGLLAYYGSMKNIRGALFT
                     GIVAGFAAVLVSTPLNMIFWGGTTGNLWGDLVYAGLLAQKFPVWFASFMDEIVVDIPD
                     KIVVLLLVLSLYKSLPKSLLSLYQSNSVIKNLD"
     gene            complement(3206..3952)
                     /locus_tag="AC1PIV_001782"
     CDS             complement(3206..3952)
                     /locus_tag="AC1PIV_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HIP6612766.1"
                     /translation="MVLQPHIRCDIEQGARYAILPGDPQRVDRVAEFLDSVEFIAFNR
                     EHKTMRGSYKGVPVLVTSTGMGGASTGIAVEELARIGVECMIRIGSCGALQPEMQMGD
                     LVILNGAVRDEGTSRAYVDPIFPAVPDPDVLFALRGTAMNQGFAHHVGIARSHDSFYI
                     DNELEVDHFWSKKGVLAGDMESAALFTIGSLRGIKTGSILNTVALYDGELKDEINQYV
                     SGENRVTQGEKNEILTTLEAIVMLEEQRKG"
     gene            complement(3964..4638)
                     /locus_tag="AC1PIV_001783"
     CDS             complement(3964..4638)
                     /locus_tag="AC1PIV_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HIP6612767.1"
                     /translation="MILKMHLLLDIIEMNPDVYSLLKLCPYEILRKIHVKRFEDGEFE
                     LEQGEIYQYMYIIVEGRVNVYSESENGKKYFLCCSQSGDLIGEMEIFQQVPYISYVKG
                     VGDIIALEIDKDTLLSWMALDQNFSSLFIKKICENSYRMCNRMKRNSLYDLRQRLAYY
                     LLEQFGGKKLASLQFNSERLSQEMAVTQRSINRLLKEFKEKQIIDLGHGKIQLLDHQA
                     LTSLLD"
BASE COUNT         1573 a         1138 c          719 g         1533 t
ORIGIN      
        1 tccgcttcaa aaagattaaa agaatagaaa cagaactacc tcaatctgca atctctcaca
       61 aacttagaat tagactaata tcgttcaata attaggaagc agtatagaat aacattataa
      121 aaaccaagcg gttaccagga atctcctaga ttgtaattta agtacatcac tcctgtttgt
      181 aagctatgaa ctcttcggga gtgagaaaaa cgtcatcata gcctagtgct tgacataatt
      241 gcatcgtggt tggctgagat agataggctt tttcaaggac atctttctgt gaaaaaacct
      301 ctcgaacact tccatctaac aaaacttctc cttgtgcaaa gacaagggca cgttcaaacg
      361 tttctgctac gaagtccata tcatgcaaaa tggaaataac tatttttcct tgttctctca
      421 acaattgtat caccgattga atctgttttt ttcctgcatc atcttgagca atcgttggtt
      481 catcaaaaat cacaacctgt gtatccatag caactattgc agcgattgac accatttttc
      541 tatcggataa tcctaagtcg tagggattta ccttgtcaaa tccatctaag cccagcaagg
      601 acatagtttt tctagctgcc tgttctgctt gagaatgagt catgcccatt tgcaatggtc
      661 caaacataat ttcatctaat accgtatgtt taaaaatttg gtcatctgga ttttgaaaaa
      721 tgagtccaat acttttagca attttagcga cagattgttc gcttaaatct tgtccattta
      781 acataatttt accagccgtc ggacgaataa ggcctttcag taactttaca aatgtagtct
      841 ttccagcacc attttgtcca ataatcgccg tcgaacgctc atctaaaata atattcaacc
      901 cttttaatat ttttttatcc ggatgatagg aaaattctaa gttactaata ctaatttgat
      961 tcatacattt ccccccctat tctttgccaa caactgacta gcttcctcaa gtgtcacagg
     1021 ataataggaa cttcctggta gcttcatgcc taactgcttg catattctag taaaggtagg
     1081 tgctacaact ccatactttt ctagatctgg tcgagaaaac acggcttgtg gtgtatccat
     1141 ggcaattagt tttccctgat caagcaacat tacccggtca ctgtaagctg cgattttttc
     1201 aaccttatgt tccaccataa ttacagtgat gccttgctta cttaaagact gaatagcttt
     1261 gaaaactgcc tcactacctt gtggatcgag ttgagaagtt ggctcatcta aaataatgac
     1321 ctctggtttc atcgccataa tgctagcaat tgccattcgt tgcatttgtc ctcctgacaa
     1381 gtcaaacgga gctcgatcac ggtactcttc aatgtccaac aaacgtaaac tttcctcaat
     1441 tcgaacttcc atttcttctt ttgggactcc gaaattctcc aaaccgaaag caatttcttc
     1501 atacacagtc gccttagaac ctgtaatttg attaaatgga ttttgaaaaa cgcttccgac
     1561 tttttggcac aagtcatcaa cctctaccct cttcacttcg gattgatcaa tccatacctt
     1621 tcctccatac gaaccacggt aaaaattcgg aacaagtcct gttaatgatt gacagaatgt
     1681 cgattttcca gaaccatttc gaccaattac cccaatgaat tcacctggac gaatctcaca
     1741 cgtgatgccg tctagagcca acttttcagc aaagggatat tggtatttta gattttcaat
     1801 tttaatatgt gccattatag aaccctccag acaattgcta gcacaactcc aaaaatgcag
     1861 aaaatttgaa tcaatcgatc aaattgcgaa cgaatcggtg gattgataaa tgtcttttta
     1921 gattttgaat taaatcctcg aacctctaag gcaattgcgc gttctctcgt atcaataaaa
     1981 gaactcataa ttacaggaga gaccaatggc aaaaaagctt ttagccgaac caacatcgaa
     2041 ccttctgttt ccatcccacg acttctttgt gcatccgtaa ttgttgccat tcggctcgtc
     2101 atctgaggga ttaattggaa caaggagaca aacacatatc ccattcgagg tgagaagcct
     2161 tttctaacta attcttcaat catgtccgac gattttgtcg ttaaaatcag aacacagaaa
     2221 gctaaaataa tattacatac atttaaagca atctcagctg caaatatcaa gccttcctta
     2281 taaaaaatga ctggacctaa ttgaaaaaca ggcgtgacat taccacttct aaacaatcct
     2341 tgaataattc ctaccgttaa aataacaaac ccagatacac tcagaatggg taaggtctgc
     2401 cttaacactt tagaatgtgc taacaaaacg acacttaaaa gaattgtaat gctaaataca
     2461 gctaaatcac ctgcaataat cggtatcaga atggtcgcaa gcacatacaa catcttagtt
     2521 aacggagaca aattattcaa aaatgaattc ttgtcttcaa acaaactcat cgttttcatg
     2581 gagacctcct taatctaggt tcttaatcac actattactt tggtaaagcg atagtagact
     2641 ctttggtaaa ctcttataca agcttagcac aagtaataat acgactattt tatctggaat
     2701 atctaccact atttcatcca taaacgatgc aaaccaaact gggaattttt gagctaatag
     2761 acctgcataa accaagtctc cccataaatt tccggttgta ccaccccaaa agatcatatt
     2821 caatggcgtt gataccaaga ctgctgcaaa tccagcaaca attcctgtaa ataaggcacc
     2881 cctgatgttc ttcatactac cgtaataagc caataaaccg actgcaattc ctagggctgc
     2941 attggttaag gcataaactg tagaaatcgg atccaccgtt aatccataaa ttaaattatt
     3001 cataattccc acaacagcac ctacaattgg accagccaaa caagccgata aacaagttcc
     3061 aatcgaatct aaccaaagtg gtaatttgag aacccccgca atcaatttac caatataatt
     3121 aatcccaacc cctgccggaa tcaacactaa agctgcagta ttaaacttca atgataatgg
     3181 attattattt ctccaattca tgattctatc ctttcctttg ttcttctagc atcacaatcg
     3241 cttccaatgt cgtaagaatt tcattttttt caccttgtgt cacacgattt tcgccagaca
     3301 catattggtt gatctcatct ttcaattcac catcatatag tgccactgta tttaaaatgg
     3361 agcccgtttt aatcccacgt aggctaccaa tagtaaataa agctgcactt tccatgtctc
     3421 cagctaatac acctttttta gaccaaaaat gatcaacttc caactcatta tcaatataaa
     3481 aactatcatg gcttctagca attccaacgt gatgggcaaa accttggttc atagcagttc
     3541 ctcgtaaggc aaataaaaca tcagggtctg gaaccgccgg aaaaattgga tcaacatacg
     3601 ccctagaagt cccctcatca cgtacagccc cattcaaaat gaccaaatct cccatctgca
     3661 tctccggttg caatgctcca catgagccaa tccgaatcat acattccaca ccgatacgtg
     3721 ccaactcttc taccgcgatt cctgttgaag caccccccat ccctgtagag gtaactaaca
     3781 ctggaacccc cttatagctt ccacgcattg ttttgtgttc acgattgaat gctataaatt
     3841 ctacactatc taaaaactct gctactctgt ccaccctctg tggatcgccc ggcaatatgg
     3901 cgtatcttgc accttgttct atgtcacaac gaatatgtgg ttgtagtacc atctttcttt
     3961 ctcctaatct agtaaactcg ttaaagcttg gtggtccaat agttgaatct taccatgacc
     4021 taaatcgatg atttgctttt ctttaaattc ttttaacaat cgattgatac tccgttgggt
     4081 aaccgccatc tcttgactca atctttccga attaaactgt aatgatgcta atttttttcc
     4141 tccaaattgc tccagcaaat agtatgcaag tcgctgtcta agatcatata gactattgcg
     4201 cttcatacga ttacacatac gataggaatt ttcacaaatc ttcttaataa acaaactact
     4261 aaagttttga tctaatgcca tccaactcaa aagtgtatct ttatctattt ccaaagcgat
     4321 aatatcacca actcctttca cataactaat atacggaact tgttgaaata tttccatttc
     4381 tccaatcaag tcaccagact gactacaaca aagaaaatat tttttcccat tttccgattc
     4441 cgagtaaaca ttgaccctcc cctcaacaat aatatacata tactgataga tctccccttg
     4501 ctccaactca aattcaccat cttcgaatct cttgacatgt attttacgca agatttcata
     4561 tgggcaaagc tttagtaatg aatatacatc tggattcatc tcgattatat ccaatagtag
     4621 atgcattttc aaaatcatac acgctccttt ctttattgtt accacaacaa tgataacgct
     4681 ttcttttttg caagtaaagg aattccgtcc gattcaatag caaaaaaaca tatccaatgt
     4741 cataatacac aaacatttta aggacaaatg tcttcttgtt ttacgatttg ttccagattt
     4801 ctaagccata ctttataaat aaattttgat aaaatcttcc taattccaag agcttttaaa
     4861 ctctaatttg tattacttaa cttctactca tttcgaatga tgaatgtttg tattgctaaa
     4921 tgcggattcc attacaaaag atgatttaat tttttgtgaa gta
//
LOCUS       DBNFCO010000102         4910 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.102, whole genome shotgun sequence.
ACCESSION   DBNFCO010000102 DBNFCO010000000
VERSION     DBNFCO010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4910)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4910)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4910
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.102"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            94..978
                     /gene="scrK"
                     /locus_tag="AC1PIV_001784"
     CDS             94..978
                     /gene="scrK"
                     /locus_tag="AC1PIV_001784"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008865 - fructokinase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase ScrK"
                     /protein_id="HIP6612768.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFQVVEKTQFPTTTPYETIERT
                     VEFFKRYEDRLAGIAIGSFGPIDIDQNSQTYGYITSTPKPHWSNIDLLGLIAKEFNIP
                     FYFTTDVNSSAFGETLVRKGVKSLVYYTIGTGIGAGAIQNGEFIGGLGHTEAGHTYVA
                     LHPYDVKHEFKGMCPFHNGCLEGLVAGPSLEGRTGIRGELIELNSDVWDVQAYYIAQA
                     AVQATLLYRPQVIVFGGGVMAQEHMLNRVREKFVGLMNDYLPTPDVKEYIVTPAVAEN
                     GSATLGNFALAKQVSRNS"
     gene            1587..4856
                     /locus_tag="AC1PIV_001785"
     CDS             1587..4856
                     /locus_tag="AC1PIV_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014917307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HIP6612769.1"
                     /translation="MIPIQQHGKRWLILTLTLSTSVLALASIGTSQPVVFADENSHLQ
                     SPKNTNKIEVLNWEAFSKKLKDYSSDQRQFHVLKLGFENRLGTLSTREELEEFGKNNN
                     FLVINGKVTQNIHDFPHILVMNKGDVIAHNEEDYHNQMRELRFSGNGDLHNSMEPKRI
                     HALFKIELDSNKRQLLNAAGLGTAENSLKNINGMTIYSHGLTVDNKYYEDYSKYTHNS
                     VKNINVTKERFIANDDLIHKLIESSEAMKQSSERDKVKAFVQYVANHTTYDWEAANKA
                     VQNYADINYYLGSDLFAVTERQKAMCVGFSTTAARAFNMLGLPAYVVVGKNAEGVPHA
                     TARVYYDKKWHTIDGTGFITGNKHQRSAKYSEKHFSTIGEDSYDVVEAGQEPKAERNY
                     MIIDSNYESWAMKQKTADLLLFNKEKSLVGLDYIAYVEPTYITENKKNHLLDIYKALK
                     RKVEETKATDKDDKDDKQEGYDRVLQFVNSDIDKLSALSKITEEEFKALENSMDLARV
                     FLGQMNAKAGKEFSEGETYQSYLKNRQKNNTNSDDDRNRNELQENQANSDEVSQNSKD
                     ASAPSVNSAQQSEELEGTPSTQETISAAPSQQTPAAPKALQAKTELEDKTETSSLGNT
                     EMVSPSSETAQNTVDSKEESDAKLPYVEPSSKESSEAQVNTVSSPQVSSASPTSSETI
                     STDTVTASQEKAESRVSAPQVISASQTSPETNSAEVVTTSQEVAKAPVSAPQVSSEIQ
                     TLSETAPTEVATEAPELSALESNPAPQTSLETTPTEEVTETPEPSVVESNSASPTSPE
                     TNSAEAVTTSQEMAEPSVSVPQVSSEIPTSSETAPAEVATEVSEESSSASQPSPETTP
                     TETVTTSQEVAEAPVSAPQVISEIPTSSETAPAEVATEVTEPSVVASSSASPTSPEAN
                     STEVVVAKQEVADPLVSAPQTSSASLTLEVPKNEHLDEKADATTPNGVEANTHEAVSV
                     PTSDIRVQDAGSDTVPQPYSLSATLFEEAISTVEPVGVATSSQERSAVAGKVKVPTSL
                     ERSNNSVEEEKVVDSNATIENREPEKKEILTSENVLNSLVTIWVALSTSFFMRYFSRG
                     K"
BASE COUNT         1640 a          863 c         1032 g         1375 t
ORIGIN      
        1 actacataat taacaggaaa aaggctttca gcctttttct tctgtttgct tatatgttat
       61 aataaaagtg ataaaaattt tggagacaat caaatgacaa aattatatgg tagcttagaa
      121 gctggtggta caaagtttgt ttgtgcagta ggtgatgaga actttcaagt tgttgaaaaa
      181 acgcaatttc caacgacaac tccttatgaa acgattgaga gaacagttga attcttcaag
      241 cgctatgaag atcgtttggc aggtattgcg ataggttctt tcggtccaat tgatattgat
      301 caaaactcac agacttatgg ttacatcact tcgacaccaa aaccacactg gtcaaatatt
      361 gatttacttg gtctgattgc taaggaattt aacattccat tctacttcac gacagatgtg
      421 aattcatcag cttttggtga aaccctggtt cgtaaagggg taaagagctt ggtttactat
      481 acaatcggta caggtattgg tgcaggtgct attcagaatg gtgagtttat cggtggcttg
      541 ggtcataccg aagcgggtca tacttacgtt gccctacacc cttacgatgt aaaacatgaa
      601 tttaaaggaa tgtgtccatt ccacaatggg tgtttggaag gcttagttgc aggtccttct
      661 cttgaaggtc gtacaggtat tcgtggtgaa ttgatcgagc tcaattcaga cgtttgggat
      721 gtgcaggctt actacattgc tcaagcagca gtacaggcaa ccttgcttta tcgtccgcaa
      781 gtaattgtat ttggtggagg agttatggct caagagcaca tgcttaatcg tgtacgtgag
      841 aagtttgtcg gtttgatgaa cgattatctc ccaacaccag atgtcaaaga atatatcgta
      901 acgccagctg ttgctgaaaa tggttctgca actcttggga actttgcttt ggcaaaacag
      961 gtgtcaagaa attcataatt gtctatgaga acagattcat ttgtactttg gcgatagata
     1021 tattgaagaa tattgggtga agttgtttta ttatcacaat aacttgacag tgaagtgaga
     1081 gtttttatgt aactctcact tctttttatc taaaaaactg tattcataag agatagccat
     1141 tcgttaatca aggcagtttt ggggagtagg aaagaactcg accagcttaa aagagttcgt
     1201 caacaactct tcaatttaag tttttgagcc gaaacagcgc ctcaaaaact aacgatgact
     1261 ataaaagatt agagtttgcc attgttggag ttcatcgggt atgaaaaaga gaaacgagtt
     1321 ccacaacttt tgatgattat tcataagcaa ggttgaaaat ctttttattg gcgatagtgt
     1381 agtgatattt tttaaccaga ggaaagttgt tgtttctcaa ttgtatgaaa acgctatatc
     1441 taaagtgatg atgcggagac actaaagtct ataaaaacag gaaaagcaca gatagatagc
     1501 agaaaaaaga tagttaaaag tgttacaatt gggatgcaaa ttttaggctg ggaaattatt
     1561 ctcagaagta cttatatgga ggacttatga ttccaattca acagcatggt aagcgctggc
     1621 ttattttgac acttaccctt tctacttcgg ttcttgcgct tgcatctatc ggaacatcac
     1681 aaccggttgt ttttgcagat gaaaactcac atttacaatc gccaaaaaac accaataaaa
     1741 tagaggttct gaactgggaa gcattttcta aaaaattgaa agactactcc tcggaccaac
     1801 gacaatttca tgttttgaaa ttaggatttg aaaatcgact gggaacatta tcaactcggg
     1861 aagaattgga agaatttggt aaaaacaaca attttttggt aatcaatggt aaagttactc
     1921 aaaatattca tgactttcca catatccttg ttatgaacaa gggtgatgtt attgctcata
     1981 atgaggaaga ttatcataat cagatgagag agttgaggtt ttcgggaaat ggcgacttac
     2041 ataatagtat ggagccaaaa cggattcatg cactatttaa gattgagctt gactccaata
     2101 aacggcagtt attaaatgct gcgggtctag gaactgctga gaatagtttg aaaaatatta
     2161 atggaatgac tatttactcg catggtctta cagttgataa taagtactat gaggattata
     2221 gtaaatatac tcataattca gttaaaaata taaacgttac caaagagcgt tttatagcaa
     2281 atgatgactt gattcataag ttgatagagt cctcagaagc tatgaagcaa tcaagtgaac
     2341 gcgataaagt taaggcattt gttcagtatg ttgccaatca tacaacatat gattgggaag
     2401 ctgctaataa ggctgttcaa aattatgcag acatcaatta ctacttagga tcagatttgt
     2461 tcgcggttac tgaacgtcag aaagcgatgt gtgtaggttt cagcactact gcggcccgtg
     2521 catttaatat gttagggctt cctgcttatg ttgttgttgg gaaaaatgca gaaggtgtcc
     2581 cgcatgctac agcgcgtgtt tattatgata aaaagtggca caccattgac ggtacaggtt
     2641 ttattacagg gaataagcat cagcgctcag ctaaatatag cgagaaacac ttttctacta
     2701 ttggtgagga tagttatgat gttgttgagg caggacagga gcctaaggcg gagcgtaact
     2761 acatgattat tgatagtaat tatgagagtt gggctatgaa acaaaaaaca gcagatttac
     2821 tgttgttcaa caaagaaaag tccttggttg gtttggatta tattgcatat gttgagccaa
     2881 cttatataac agaaaataag aaaaatcatt tgctagacat ctataaagct ttgaaacgta
     2941 aagtagaaga aacgaaagca acggataaag acgataaaga tgataaacaa gaggggtatg
     3001 atcgtgtttt acaatttgtc aattctgata ttgataaatt gagtgctctc tccaagatta
     3061 cagaagaaga atttaaagca ctcgaaaatt caatggattt agctcgagtg ttcttggggc
     3121 aaatgaatgc gaaggctgga aaagaatttt cggaaggaga aacttatcaa agttatctaa
     3181 agaatcgtca gaaaaataac acaaattctg atgatgatag aaaccgaaat gaattgcaag
     3241 aaaaccaagc taattctgat gaagtcagcc aaaattccaa ggatgcttcg gctccaagtg
     3301 ttaattctgc acagcaatct gaggagcttg aaggaactcc ttcaacacag gaaacaatct
     3361 cagctgctcc ttctcaacaa acaccagcag ctcctaaggc actacaagct aaaactgagt
     3421 tagaggataa aacagagact tcatctttag gaaatacaga gatggtttca ccgagttcag
     3481 aaacagctca gaatacagtt gattctaagg aagaaagtga tgctaaatta ccatatgttg
     3541 agccttcatc caaagaatcg agtgaagcgc aggttaatac agtttcctct ccacaagtaa
     3601 gttctgcatc cccaacttca tcagaaacta tttctacaga tacggtaaca gctagtcaag
     3661 aaaaagctga atcacgggtt tctgccccac aagtaatttc agcatctcaa acttcaccgg
     3721 aaactaattc tgccgaggtg gtaacaacta gtcaagaagt agctaaagca ccggtttctg
     3781 ctccacaagt aagttctgaa atccaaactt tatcagaaac agctcctaca gaggtggcaa
     3841 cagaagcacc ggaattaagt gcacttgaga gtaatccagc acctcaaact tcattggaaa
     3901 caactcctac agaggaggta acagaaacac cggaaccaag tgtagttgag agtaattcag
     3961 catccccaac ttcaccggaa actaattctg cagaggcagt aacaactagt caagaaatgg
     4021 ctgaaccttc ggtttctgtt ccacaagtaa gttctgaaat cccaacttca tcagaaacag
     4081 ctccagcaga agtggcaaca gaagtatcgg aagagagtag ttcagcatct caaccttcac
     4141 cggaaacaac tcctacagag acggtaacaa ctagtcaaga agtagctgaa gcaccggttt
     4201 ctgctccaca agtaatttct gaaatcccaa cttcatcaga aacagctcca gcagaagtgg
     4261 caacagaagt aacagaacca agtgtagttg cgagtagttc agcatcccca acttcaccgg
     4321 aagctaattc tacagaggtg gtggtagcta aacaagaagt agctgaccca ctggtttctg
     4381 ctccacaaac aagttctgct tcacttactt tagaggttcc taaaaatgaa catttagacg
     4441 agaaagcaga tgcaactacg ccaaatggag ttgaagcaaa tactcatgag gcagtttctg
     4501 ttccgacatc agatattcgt gttcaagatg ctggttcaga cacggtgcct caaccttact
     4561 ctttatctgc gacattgttt gaagaagcaa tttcaacagt tgagcctgta ggtgttgcaa
     4621 cttcttctca agagagaagt gcagtagctg gcaaggtgaa agtgcctacc tctcttgaac
     4681 gtagtaacaa ttctgttgag gaagaaaaag tggtcgattc aaatgcaaca attgagaatc
     4741 gagagccaga gaaaaaagag atccttactt cggaaaatgt acttaacagc ttagtaacaa
     4801 tttgggtagc tttatctact agtttcttca tgagatattt ttctcgagga aaataatata
     4861 ttaacacagg ttaaagatga cgtttatctt tgtgtagaaa attattcatg
//
LOCUS       DBNFCO010000103         4862 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.103, whole genome shotgun sequence.
ACCESSION   DBNFCO010000103 DBNFCO010000000
VERSION     DBNFCO010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4862
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.103"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            2..1090
                     /locus_tag="AC1PIV_001786"
     CDS             2..1090
                     /locus_tag="AC1PIV_001786"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HIP6612770.1"
                     /translation="MGGGIVGSTAAFYLSQEEQVNLTLIDSGVGTATRAAAGIIGPWM
                     AQKKNKDWYKLTSDGAVFYRQLVADLEKSGATEIPFKQTGTIGLKSKPELLDKIQKIA
                     EERRVDTPTIGEITPLIGSEINQYLPLLKPDYFGIHLEGGGRIDGGRLIDILQEQFLK
                     NGGTRIYGQAKLLDNHTVEVDNQVLTADHIILATGAWLPHILEPLGYQVDVRPQKGQL
                     FELDTEFDTDNWPVCMPYGEIDILPFENGKIIIGATHEDDMGYDLELDPEKIQAMHDK
                     IAEFMPDLANYPVTRTRIGTRAYTSTYSPFYGNIEDMPNVWVASGLGSTGLTNGPIIG
                     WQIAKEILNQETNFDRTPYSPNRYILKK"
     gene            complement(1415..4840)
                     /gene="ide-Ssuis"
                     /locus_tag="AC1PIV_001787"
     CDS             complement(1415..4840)
                     /gene="ide-Ssuis"
                     /locus_tag="AC1PIV_001787"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host-specific IgM cysteine endopeptidase
                     Ide-Ssuis"
                     /protein_id="HIP6612771.1"
                     /translation="MNIQERFSLRKSAVGLVSVSLLCAIYTSTVAADTVVTGVNEIIE
                     ESQVKDEVSIESEKNESLDGSNIEIVEEIADNIPSPVIAEGEVAVEMKVDRGTENVVS
                     RNDTEVTTSEQNQIEVTETKEILNQTSYQTESGEQRQIIWAHGITPPAMEQSGGFVKE
                     KYGDYLNYTAPFEAGKGYYDTNKSLNASFIDLNLCFAAVSSNMVHWWLEQNSSYVERY
                     LKEKKGTVNVEENYAITDLRRYINSFQNQQNSRVFDMFKTYYGYRTNGFVSDALVDLF
                     INGYKPKAQGGVNLEDSQLVPDSRGGFFYDVFKEKKLTNRIFSGSYERFGEDVRTVLE
                     SKGLLGLTYRTLGYATHIVTVWGAEYDNQGKIKAVYITDSDDQQEQIGLKRMGITRDA
                     SGNPRLNNHMKNNSAGALLDYVHTIRLGQDLWEEYFNPLAKAKETASQTLADTKKALD
                     LSIQGQSELPESMRLIYLEKLNNLYNQGILSIQKAESSEMLSGALENGLNSLKSLDFP
                     ISEVGNALAPDLPVGDRSTVSDVDSLSSQETSSTNLEADTENAGIIADGTNQLHFPVE
                     AQTTSSVEAEGDNVFEQEADTLPIIIENKDEFGSELSRNMQTSETDSLVVAVEEDVKN
                     DEVAQVEELLESEKVENQSSELLSDTLIVESANDKEEDRVEAVVSEQPDSIPHQNVEI
                     SLVEPTNVETETVVTPINDAATPHGSPTYIDNSVTESVATPLEKDSIQAGETEIAEPT
                     SSESTNVETETVVTPVNDVATPHGSPTYIDNSVTESVATPLEKDSIQAGETEIAEPTS
                     SESTNVETETVVTPVNDVATPHGSPTYIDNSVTESVATPLEKDSIQAGETEIAEPTSS
                     ESTSVEAELVDNSEIHAATSSVTPCGSSAYADGSTTESVATPLEKDSIQTGNTEIAEP
                     TSSKSTNVEAASVDNSEIHADASLTAVSSVNLDNPVIEPVAISLIGSKRDTNAEVEVS
                     SLSKREVRKTNTDGLISVQSKVIKKELLESSLAEAGSPLLEATIAQSSNSNSTEIGMS
                     YQNTVLLESNNTERQVSKAEIVMEHKETELVETVSSASEPVVLVENISQTSNNTIESG
                     KNMGVQSQAGAKQILGVEQSSKVSTPTSRQIMGVGLLTLVLGSALGLLKKRRK"
BASE COUNT         1387 a         1034 c          894 g         1547 t
ORIGIN      
        1 tataggcgga ggaattgttg gctctactgc agccttttat ctctcccaag aagaacaagt
       61 caatcttact ctcattgatt caggggtcgg aacagccaca cgagctgccg caggtatcat
      121 cggcccatgg atggctcaga aaaaaaataa agactggtat aagctgactt ccgatggtgc
      181 tgttttctac cgtcaattgg tagccgattt ggaaaaatcg ggtgctactg aaattccatt
      241 caaacagact ggaaccatcg gcctaaaaag taagcctgaa ctacttgata aaatccaaaa
      301 aattgccgag gaacgtcgcg tagatactcc gactattggc gaaattactc cgcttatagg
      361 ctcggaaatt aaccagtacc tgccactact taagccagac tattttggta tccatttaga
      421 aggtggcggt cgtattgatg gtgggcgttt gattgatatt cttcaggaac aatttttgaa
      481 aaatggtggt acacgtatct acggacaggc aaaactgctc gacaaccata ctgtcgaagt
      541 agataatcaa gtgcttactg ctgaccatat tatcttagcc acaggggcct ggttaccaca
      601 tattcttgaa cctcttggct atcaagtgga tgttcgacca caaaaaggac aattgttcga
      661 attagataca gaattcgata ccgacaattg gccagtttgt atgccttacg gagagattga
      721 tatcctacca tttgaaaatg ggaaaatcat tattggtgca actcatgaag atgacatggg
      781 ctacgattta gaactagacc ctgaaaaaat ccaagccatg catgataaaa tagctgaatt
      841 catgcctgat ttggcaaact atcctgtaac cagaactcgc attggaacgc gcgcctatac
      901 ttcaacttat tcaccattct acggaaatat tgaggatatg cctaatgtct gggtagctag
      961 tggtctaggc tccaccggtc tgacaaacgg tccaattatc ggttggcaaa ttgctaaaga
     1021 aattctcaat caagaaacaa actttgaccg tacaccatat tctccaaata gatatattct
     1081 caaaaaataa gatacgatac gtttagattc tactaaccct ttaaatgtag atactaagac
     1141 tagttgttat ctaaccaata aatacaataa gcaacgggga acctcgttgc ttatttctat
     1201 ctagaatact accattctag tctcaaacta ttaaaggatt atctatagca tgttatcgca
     1261 accatagaaa ctgattcact taaaaaccta attcgttgaa aatatagtct tttagtttac
     1321 ttttagtact aggcaacgag ccgcaggcat aactggagtt aggtaaggcg agttaacgaa
     1381 gtaataaaag aaaaactaaa tgacgatact tcttttactt acgtcttttc tttaacaaac
     1441 ctaaagcact accaagaaca agagtcaata gaccgactcc cataatctgt cttgaagtag
     1501 gtgtacttac tttcgaagat tgttctacgc ctaaaatttg ttttgcacct gcttgagatt
     1561 gaactcccat attcttacca gattcaatag tattatttga ggtttgtgag atattttcta
     1621 cgagcactac aggctcagaa gcagatgaaa ccgtttcaac taactctgtc tccttgtgtt
     1681 ccataacaat ttctgcttta gacacctgac gctctgtatt attagactct aataacacag
     1741 tattctgata gctcatacct atctcagtac tatttgagtt tgaagactga gcaatggtgg
     1801 cttctagcaa tggagaccct gcttctgcta agcttgattc tagcaattct ttcttaataa
     1861 cttttgattg aacagagatt agcccgtcag tatttgtttt tctaacctct cttttcgata
     1921 atgaagaaac ttctacttct gcattcgtgt ccctcttaga accgataagg gagatagcta
     1981 ctggttcaat cactggatta tccagattaa ctgatgaaac agcagttaga gaggcatctg
     2041 catgaatttc agaattgtcg acagatgcag cttctacatt agttgatttg ctcgaggttg
     2101 gttctgcaat ttctgtattt ccagtctgaa tggagtcttt ttcaagcgga gtggctacag
     2161 attcagttgt ggaaccatct gcatatgccg aggagccaca gggagtaact gaagaggtag
     2221 ctgcatgaat ttcagaattg tcgacaagtt cagcttcaac actagttgat tcgctcgagg
     2281 ttggttctgc aatctctgtc tccccggctt gaatggagtc tttttcaagt ggagtagcta
     2341 cagattcagt tacggaatta tctatatacg tcggggaacc atgaggagta gctacatcat
     2401 taacaggagt gaccacagtt tcagtttcga cattcgttga ttcgctcgag gttggttctg
     2461 caatttctgt ctctccggct tgaatggagt ctttttcaag tggagtagct acagattcag
     2521 ttacggaatt atctatatac gtcggggaac catgaggagt agctacatca ttaacaggag
     2581 tgaccacagt ttcagtttcg acattcgttg attcgctcga ggttggttct gcaatctctg
     2641 tctccccggc ttgaatggag tctttttcaa gtggagtagc tacagattca gttacggaat
     2701 tatctatata cgtcggggaa ccatgaggag tagctgcatc attaatagga gtgaccacag
     2761 tttcagtttc gacattcgtt ggttctacaa gagagatttc tacattttga tgtggtattg
     2821 agtctggttg ttcagaaaca accgcctcca ctctatcttc ttctttgtca tttgcactct
     2881 ctacgattag ggtgtctgac agaagttccg aactctgatt ttcaactttt tctgattcaa
     2941 gaagctcttc aacttgggct acctcatcat ttttcacatc ttcttcaaca gctactacta
     3001 gcgaatccgt ttctgacgtt tgcatgtttc ttgatagttc tgaaccaaat tcatccttgt
     3061 tttcaataat tattggtaat gtatctgcct cttgttcaaa aacattatct ccctcagcct
     3121 ctactgaaga tgtcgtttgg gcctccactg gaaaatgcaa ttgattggta ccatctgcaa
     3181 taatacctgc attctctgtg tctgcttcca aatttgtgga acttgtttct tgagatgata
     3241 gagaatcaac atctgaaacc gttgagcgat cacctactgg taaatctggt gccaaagcat
     3301 ttccaacttc tgaaatagga aaatctaaac tctttaaact atttaaacca ttttccaatg
     3361 caccacttag catctcagaa ctttctgcct tttgaataga tagaattcct tgattataga
     3421 gattatttag tttttcaaga taaatcagtc gcattgattc tggcaattca gattgtcctt
     3481 gaatagacaa atccaacgcc ttctttgtat cggctaatgt ctgactagct gtttctttgg
     3541 cttttgcaag cggattgaaa tattcttccc ataagtcttg acccagacgg attgtatgga
     3601 cataatccaa aagcgctcca gctgaattat ttttcatatg attattcaaa cgtggatttc
     3661 cggaagcatc acgagtgatt cccatacgct tcaaaccaat ttgttcttgt tgatcatcag
     3721 aatctgtgat atagacagcc ttaatcttac cttgattgtc gtactcagca ccccataccg
     3781 tcacaatatg cgttgcataa cctaatgttc tataagttaa gccgagtaat cctttgcttt
     3841 ccaaaacagt tcgaacatcc tcaccaaacc gctcataact accactaaaa attcgatttg
     3901 tcagtttttt ctctttgaaa acgtcgtaga aaaagccacc cctactatct ggtactaact
     3961 ggctatcttc cagattgaca ccgccctgtg ccttaggttt atatccgtta ataaacaagt
     4021 caaccaaggc atctgataca aaaccatttg tacgataacc atagtaagtt ttgaacatat
     4081 caaaaactcg actattttgt tgattttgga atgaattaat atagcgccgt aagtccgtta
     4141 ttgcgtagtt ttcttcaaca tttactgtac cctttttttc tttgagatat cgctcaacat
     4201 aggaactatt ctgttccaac caccaatgta ccatgtttga agacacagct gcaaaacaaa
     4261 gattaaggtc aataaatgaa gcattcagac tcttattggt atcatagtag ccttttccag
     4321 cctcaaatgg cgctgtatag tttaaatagt ctccatactt ttcctttaca aaaccaccgc
     4381 tttgttccat tgcaggagga gtaattccat gggcccatat aatttgtcgt tgctcgccac
     4441 tctccgtttg ataactggtc tgattcaaaa tttcttttgt ctcagtaacc tctatctgat
     4501 tttgctcgct cgtcgtaact tctgtatcat ttctagaaac tacattctcg gtccctctgt
     4561 caactttcat ctctaccgct acttcccctt cagcgataac aggtgatggg atgttgtctg
     4621 ctatttcctc tacaatttca atattagaac catctaggga ttcatttttt tctgattcaa
     4681 tagatacctc atccttgact tgtgattctt caattatttc attcactcct gtaacaactg
     4741 tatcggcagc aacagtggat gtataaatag cacatagcaa agagactgag accaagccaa
     4801 ccgcggattt tctcaaagaa aatcgttctt gaatgttcat ctttcctccg tttatattta
     4861 ta
//
LOCUS       DBNFCO010000104         4779 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.104, whole genome shotgun sequence.
ACCESSION   DBNFCO010000104 DBNFCO010000000
VERSION     DBNFCO010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4779)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4779)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4779
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.104"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(71..1291)
                     /gene="pepT"
                     /locus_tag="AC1PIV_001788"
     CDS             complement(71..1291)
                     /gene="pepT"
                     /locus_tag="AC1PIV_001788"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0045148 - tripeptide aminopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HIP6612772.1"
                     /translation="MKYPTLLDRFLVYVKENTRSDENSTTTPSTQNQVEFAQNILLPE
                     MERIGLQNVHYLPNGFAVGTLPANDPSLTRKIGFIAHMDTADFNAEGVNPQIIENYDG
                     NPIALGTSGYELHPKDFPQLANYHGQILITTDGTTLLGSDDKSGIAEIMTAIEFLIQN
                     PDIKHCEIRVGFGPDEEIGVGADKFDVKDFDVDFAYTMDGGPLGELQYETFSAAGAKI
                     DFLGRNVHPGSAKDQMINAFQMAIDFHNALPETDRPEKTEGYEGFFHLMNMEGSVDTA
                     STTYIIRDFEEEDFQARKQLMLDIAEKMNANFDTPRVIVNLHDQYYNMKKIIEKDMTP
                     INIAKDVMENLGIKPLIEPVRGGTDGSKISFMGIPTPNIFAGGENMHGRFEFVSLETM
                     EKAVDVILGIVAYK"
     gene            complement(1301..2116)
                     /locus_tag="AC1PIV_001789"
     CDS             complement(1301..2116)
                     /locus_tag="AC1PIV_001789"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HIP6612773.1"
                     /translation="MIKLIALDMDGTLLNEKKELMQPQIDAIHQAVEAGFKIVLCTGR
                     PLAGVKPFVEQLGFDTEEEFIIVNNGCSTHSTKDWSLIDWEELSISDIDYLSTFIENA
                     DVQISLFDEEDYFVLAEKANARVNLDAGLVGMTPQPIDLKEAQSGQYRFFEAMFVGEK
                     VHIDAFENQHNPVLSKRYSTVRSQDYLLEILPNGASKASGLKKLADRLGILPEEIMAM
                     GDANNDLEMIEFAGLGIAMGNANEQVKAIAQDITDTNENNGVAKAIEKHILNK"
     gene            2498..2968
                     /locus_tag="AC1PIV_001790"
     CDS             2498..2968
                     /locus_tag="AC1PIV_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HIP6612774.1"
                     /translation="MKISVKKEAGHYLFSICYSVSASLAESWDLLATDSGFAHWFPQL
                     NIVGNTLVFEMEGFREVMDLLEYRKNEKIAYRWDSATVSFALSQLENQTLITFEERIP
                     EDFGNEFANAQKDMTGWLVQNECIKKFLEGQEPPVCQPLQEKWRTFLELELEGL"
     gene            2986..3243
                     /locus_tag="AC1PIV_001791"
     CDS             2986..3243
                     /locus_tag="AC1PIV_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612775.1"
                     /translation="MKKWWEQLKEEYYETRFDSNEDWMEWFIKRKMTWGWRWPTAITI
                     FVLWALSLPDARNAVRFFYFLLALGVATVLHKLISYLKRRK"
     gene            3250..4503
                     /locus_tag="AC1PIV_001792"
     CDS             3250..4503
                     /locus_tag="AC1PIV_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HIP6612776.1"
                     /translation="MHQITCPHCGTAFQVNETEYSQLLAQVRGAEFDKEIYDRLERER
                     ELLSQKAENDLQARLSDKDKEILELTAKLDKFASQTELEISSAISQKDQEIQELKAQL
                     GQIGLAKDLELQQAVAQVEKERDAAQNALVLQEQKQELALATTRQEYEVRLKAADEQV
                     EFYKNFKAQQSTKAIGESLEQFAEAEFNKVRSYAFPRAKFAKDNEVSASGSKGDFIFR
                     DFDESGLEFISIMFEMKNEADTTKTKHKNADFFKELDKDRREKKCEYAVLVSMLEADN
                     DYYNIGIVDVSHEYEKMYVIRPQFFIQLIGILRNAALNSLQYQQELALVKEQNIDITH
                     FEEDLEIFKNAFAKNYQSASNNFQKAIDEIDKAIKRMEAVKAALTTSENQLRLANNKL
                     DDVSVKKLTRNNPTMKAKFEALRED"
     gene            4505..>4779
                     /locus_tag="AC1PIV_001793"
     CDS             4505..>4779
                     /locus_tag="AC1PIV_001793"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HIP6612777.1"
                     /translation="MIVPLQFEHILQLDEAFQKQGWPSRKEILTNYLREQEKGERIVL
                     VAEETGVCKGYITLIKQVKEGQFYQSGIPEIADFNVFEDFQNQGIGW"
BASE COUNT         1395 a          874 c         1150 g         1360 t
ORIGIN      
        1 aacataaaat ggcatttttt taaaattttt tcagaaaaaa acgactttct attgaaagcc
       61 gtttgaaatt ttatttgtaa gcgacgattc caaggatgac atcgacggct ttttccatgg
      121 tttctaagct gacgaactcg aagcgaccgt gcatgttttc gccacctgcg aagatatttg
      181 gtgttggaat gcccatgaag gaaatcttag agccgtctgt tcctccgcga acaggctcaa
      241 tcagtggctt gatgcctaga ttttccataa cgtccttagc aatgttaatt ggagtcatat
      301 ctttttcgat gattttcttc atgttgtagt actggtcatg taggttgaca atgacgcgtg
      361 gagtgtcaaa gttggcattc atcttttcag cgatgtccag catgagttgc ttgcgggctt
      421 ggaaatcttc ttcctcaaag tcgcggatga tataggtggt agaagcagta tcaacgctgc
      481 cctccatgtt catcaagtgg aagaaacctt catatccttc ggttttttca gggcggtctg
      541 tttctggaag ggcattgtgg aaatcaatag ccatttggaa ggcattgatc atctggtcct
      601 tagcagatcc tgggtggaca ttgcgtccta ggaaatcaat ctttgcacct gctgctgaga
      661 aggtttcgta ctggagttcg cccagcggtc caccgtccat agtgtaggca aagtccacat
      721 cgaagtcttt cacatcaaac ttgtctgctc cgacaccgat ttcttcgtca ggaccaaagc
      781 cgacacggat ttcgcagtgt ttgatgtcgg ggttttggat taggaattca atagctgtca
      841 tgatttctgc aattcctgat ttgtcatcag agcctagcaa ggtagtaccg tctgtggtaa
      901 tcaggatttg accgtggtag ttggcaagtt gtgggaagtc ttttggatgc aattcatagc
      961 cagaagttcc caaggcaatt gggttaccgt cgtagttttc gataatctga ggattcacac
     1021 cttctgcgtt gaaatcagcc gtatccatgt gggcgatgaa gccaatcttg cgggtcaaac
     1081 ttgggtcgtt ggcaggcagt gttcccactg caaaaccgtt tggtaggtag tggacattct
     1141 gcaaaccaat ccgttccatt tcaggcagaa ggatattctg tgcaaactcg acttggtttt
     1201 gggtagaagg agtggttgtc gaattttcat ctgagcgagt attttctttg acatagacca
     1261 agaaacggtc taagagtgtt gggtatttca tattgtctcc ttatttgttc aaaatgtgtt
     1321 tttcaatggc cttggcaacg ccgttgtttt cattggtgtc tgtgatgtcc tgggcgatag
     1381 ccttgacctg ctcgttggca tttcccatgg caataccaag tccagcaaat tcaatcattt
     1441 ccaggtcgtt gttggcatct cccatagcca tgatttcttc tgggaggata ccgaggcggt
     1501 ctgccaattt ttttaaacca gaggccttgc tggcaccgtt tggtaaaatt tccaagagat
     1561 agtcctgtga acgaacggtg gaatagcgtt tgctgagtac aggattgtgt tgattttcaa
     1621 aggcatcaat atgcactttt tcaccgacaa acatggcttc aaagaagcga tactgacctg
     1681 actgggcttc ttttaaatca attggttgag gagtcattcc taccaaacct gcgtctaaat
     1741 taacgcgtgc attggctttt tctgcaagaa cgaagtagtc ttcctcatca aaaagagaga
     1801 tttgcacatc agcattttca ataaaagtgg aaagataatc aatatcagag atagatagtt
     1861 cttcccagtc aatcaggctc caatcctttg tcgaatgggt tgaacagccg ttattgacaa
     1921 tgataaattc ttcctcggtg tcaaagccga gctgctctac gaaaggttta acaccagcca
     1981 agggccgacc agtacaaaga acaatcttga agcccgcttc aacagcctga tgaatggcat
     2041 caatctgtgg ctgcatcagc tcttttttct cgtttaaaag ggttccgtcc atatcaagag
     2101 cgattagttt tatcatataa acctccttgt tttcaataca tctagtatag cataaaatga
     2161 gaaaggaatg attgaaatac taaactctgt tctatatgtt aaaataaatt aggtgacgaa
     2221 tgaaatatag aagtgtttca aaaatgacaa tgtccattat gtggcaggaa agtctaacat
     2281 tgctagggga tacaaaacat ggagtatgag ccagataaac aaaggtaagg acagtctatg
     2341 aaagatgtta taaaaaataa ttcagatttc aagataccgt ttttcgatcc tctggaatga
     2401 atagcattca tgcttaaaga atagagacaa tggaaatatc ggttatagac cggtgttttt
     2461 tggtataatt aatagaagga tagaatagga gcatgatatg aagattagtg tgaagaaaga
     2521 ggcggggcac tacctgttca gcatttgcta ttctgtgtcg gctagtttgg cggagtcctg
     2581 ggatttgttg gcgacagaca gtggttttgc ccactggttt ccacagttga acattgtagg
     2641 aaatacgctg gtttttgaaa tggaaggatt tcgtgaagtt atggatttac tggaataccg
     2701 aaaaaatgag aaaattgcct acaggtggga ttcagcaaca gtttcatttg cactgtctca
     2761 gctagaaaat cagaccttga ttacttttga agaacgaatt ccagaagatt ttggtaatga
     2821 atttgcgaat gctcaaaaag acatgacagg ctggttggtg caaaatgaat gtatcaaaaa
     2881 attcttagaa ggtcaggagc cgcctgtgtg tcaacccttg caggaaaagt ggaggacttt
     2941 tctggagctt gaattagaag gtctgtgatc tgaaaggagg ctgttatgaa aaagtggtgg
     3001 gaacaactga aagaagaata ttatgaaaca cggtttgatt ctaatgaaga ttggatggaa
     3061 tggtttatca aacggaagat gacctggggc tggagatggc cgactgccat aacgattttt
     3121 gtcctttggg ctctatcact tccagatgct agaaatgcgg ttcgtttctt ttatttttta
     3181 ttggcgctgg gagtagctac ggttttacat aaattaatat cttatttgaa aagaagaaag
     3241 tgagagtata tgcatcaaat tacttgcccc cattgtggga cggcctttca ggtcaatgaa
     3301 acagaatata gtcagctttt agcccaagtg cgtggtgcgg agtttgataa ggaaatctac
     3361 gaccgtttgg agcgggaacg ggaattatta agccagaagg ctgaaaatga tttgcaggct
     3421 agattgagtg ataaggataa ggagattctg gaactgaccg caaaacttga taaatttgct
     3481 agtcagacgg aactggaaat cagctctgct atttcccaaa aagaccaaga aatccaagag
     3541 cttaaggctc agttggggca aatcggtctc gccaaggact tggagttgca gcaggcggta
     3601 gctcaggtgg aaaaagagag ggatgcggca caaaatgctt tggttttgca ggaacaaaag
     3661 caagagttag ccctggcgac cactcgtcag gagtacgaag tacggctcaa ggcggcggat
     3721 gagcaggtgg aattttacaa aaatttcaag gctcagcagt ctactaaggc aattggagag
     3781 agcttggagc aatttgctga ggcggagttt aacaaggttc gttcctatgc ttttccacgt
     3841 gccaaatttg ctaaggacaa cgaagtatca gcgtccggtt caaaaggaga tttcatcttc
     3901 cgtgattttg acgagtcggg cttggaattt atttccatca tgttcgaaat gaaaaacgag
     3961 gcagatacga ccaagaccaa gcataaaaac gctgatttct ttaaggagtt ggataaggac
     4021 cgtcgggaga aaaaatgcga atatgctgta ttagtcagca tgctagaggc ggacaatgac
     4081 tattacaata tagggattgt ggatgttagt catgaatatg agaagatgta tgttattcga
     4141 ccacagttct ttatccaatt aatcggaatt ttacgaaatg ctgcgctcaa tagtctgcaa
     4201 tatcagcagg agttagcctt ggttaaggag cagaatattg atattactca ttttgaagaa
     4261 gatttggaaa ttttcaagaa tgcttttgcc aaaaactatc aatcggccag caacaatttc
     4321 caaaaagcta ttgatgaaat cgacaaggca atcaagcgaa tggaggctgt caaagcagcc
     4381 ctgaccacca gcgaaaacca gcttcgccta gctaataata aactagacga tgtctccgtc
     4441 aaaaaactaa cccgcaataa cccaaccatg aaagccaagt ttgaggcgtt gagggaggat
     4501 tgagatgatt gttccgttac aatttgagca tatacttcaa cttgatgagg ccttccagaa
     4561 gcaaggttgg ccctcccgca aagagatttt aaccaactat ttaagggaac aagaaaaggg
     4621 agaacgtatc gtcctagttg ctgaagaaac gggggtttgt aaaggttata tcaccttgat
     4681 taagcaagtg aaggagggac agttttacca atctggaata cctgaaattg ctgatttcaa
     4741 tgtttttgaa gactttcaaa atcaggggat aggttggca
//
LOCUS       DBNFCO010000105         4636 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.105, whole genome shotgun sequence.
ACCESSION   DBNFCO010000105 DBNFCO010000000
VERSION     DBNFCO010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4636
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.105"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            14..748
                     /gene="yaaA"
                     /locus_tag="AC1PIV_001794"
     CDS             14..748
                     /gene="yaaA"
                     /locus_tag="AC1PIV_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HIP6612778.1"
                     /translation="MKIIIPNAKEVNTNLENASFYLLSDRSKPVLDAISQFDVKKMAA
                     FYKLNEAKAELEADRWYRIRTGQAKTYPAWQLYDGLMYRYMDRRGIDSKEENYLRDHV
                     RVATALYGLIHPFEFISPHRLDFQGSLKIGNQSLKQYWRPYYDQEVGDDELILSLASS
                     EFEQVFSPQIQKRLVKILFMEEKAGQLKVHSTISKKGRGRLLSWLAKNNIQELSDIQD
                     FKVDGFEYCTSESTANQLTFIRSIKM"
     gene            853..2298
                     /locus_tag="AC1PIV_001795"
     CDS             853..2298
                     /locus_tag="AC1PIV_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HIP6612779.1"
                     /translation="MKKRSGRSKSSKFKLVNFALLGLYSITLCLFLVTMYRYNILDFR
                     YLNYIVTLLLVGVAVLAGLLMWRKKARIFTALLLVFSLVITSVGIYGMQEVVKFSTRL
                     NSNSTFSEYEMSILVPANSDITDVRQLTSILAPAEYDQDNITALLDDISKMESTQLAT
                     SPATSYLTAYQSMLNGESQAMVFNGVFTNILENEDPGFSSKVKKIYSFKVTQTVETAT
                     KQVSGDSFNIYISGIDAYGPISTVSRSDVNIIMTVNRATHKILLTTTPRDSYVAIADG
                     GQNQYDKLTHAGIYGVNASVHTLENLYGIDISNYVRLNFISFLQLIDLVGGIDVYNDQ
                     EFTSLHGNYHFPVGQVHLNSDQALGFVRERYSLTGGDNDRGKNQEKVIAALIKKMSTP
                     ENLKNYQAILSGLEGSIQTDLSLETIMSLVNTQLESGTQFTVESQALTGTGRSDLSSY
                     AMPGSQLYMMEINQDSLEQSKAAIQSVLVEK"
     gene            2316..3005
                     /locus_tag="AC1PIV_001796"
     CDS             2316..3005
                     /locus_tag="AC1PIV_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Wzz/FepE/Etk N-terminal domain-containing
                     protein"
                     /protein_id="HIP6612780.1"
                     /translation="MNNQEVNAIEIDVLFLLKTIWRKKFLILLTAVLTAGLAFVYSSF
                     LVTPQYDSTTRIYVVSQNVEAGAGLTNQELQAGTYLAKDYREIILSQDVLTQVATELN
                     LKESLKEKISVSIPVDTRIVSISVRDADPNEAARIANSLRTFAVQKVVEVTKVSDVTT
                     LEEAVPAEEPTTPNTKRNILLGLLAGGILATGLVLVMEVLDDRVKRPQDIEEVMGLTL
                     LGIVPDSKKLK"
     gene            3015..3692
                     /locus_tag="AC1PIV_001797"
     CDS             3015..3692
                     /locus_tag="AC1PIV_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="HIP6612781.1"
                     /translation="MAMLEIARTKREGVNKTEEYFNAIRTNIQLSGADIKVVGITSVK
                     SNEGKSTTAASLAIAYARSGYKTVLVDADIRNSVMPGFFKPITKITGLTDYLAGTTDL
                     SQGLCDTDIPNLTVIESGKVSPNPTALLQSKNFENLLATLRRYYDYVIVDCPPLGLVI
                     DAAIIAQKCDAMVAVVEAGNVKCSSLKKVKEQLEQTGTPFLGVILNKYDIATEKYSEY
                     GNYGKKA"
     gene            3731..4462
                     /gene="cps4B"
                     /locus_tag="AC1PIV_001798"
     CDS             3731..4462
                     /gene="cps4B"
                     /locus_tag="AC1PIV_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4B"
                     /protein_id="HIP6612782.1"
                     /translation="MIDIHSHIIFGVDDGPKTIEESLSLISEAYRQGVRYIVATSHRR
                     KGMFETPEKIIMINFLQLKEAVAEVYPEIRLCYGAELYYSKDILSKLEKKKVPTLNGS
                     CYILLEFSTDTPWKEIQEAVNEMTLLGLTPVLAHIERYDALAFQSERVEKLIDKGCYT
                     QVNSNHVLKPALIGERAKEFKKRTRYFLEQDLVHCVASDMHNLYSRPPFMREAYQLVK
                     KEYGEDRAKALFKKNPLLILKNQVQ"
BASE COUNT         1510 a          789 c          989 g         1348 t
ORIGIN      
        1 gtataattaa gtgatgaaaa taattatacc taatgcaaaa gaagtaaata caaatctaga
       61 gaatgcctcg ttttatctcc tgtctgatcg aagcaagccg gtgctggatg ccataagtca
      121 atttgatgta aaaaagatgg ctgcctttta taaattgaat gaagcaaagg ctgagttaga
      181 agctgaccgt tggtatcgaa tcaggacagg tcaagcaaaa acctatccag cctggcagtt
      241 atatgatggt ctcatgtatc gttatatgga taggcgaggt atagattcga aagaagaaaa
      301 ttatctacgt gaccacgttc gtgtagcgac agccttatac ggattgattc atccttttga
      361 attcatttca cctcaccgct tagattttca agggagctta aagataggca atcagtcttt
      421 gaaacagtac tggcgaccgt attatgacca agaagttggt gatgatgaac tgattctctc
      481 actggcttcg tcagaatttg agcaggtgtt ttctccacag attcagaaaa gattagttaa
      541 aattcttttc atggaagaaa aagcaggtca gctaaaagtt cactcgacta tatcaaaaaa
      601 aggcagagga agattgctgt cctggttggc taagaacaat attcaggaat tatcggacat
      661 tcaagatttt aaggtggatg gctttgaata ttgtacttcc gaatcaacgg caaaccaact
      721 taccttcata cgatcaataa aaatgtgaaa ttatgaaaaa gataacgttt tccagcgcta
      781 aaaagggtag aaaaatatta atttctatga tataatggat gcgttatagg taaaagtcta
      841 ggaaggttgt ttatgaaaaa gagaagcgga cgaagtaagt cgtccaagtt caaattggta
      901 aattttgcgc ttttgggact ttattccatt actctatgtt tgttcttagt gaccatgtat
      961 cgctataaca tcctagattt ccggtattta aactatattg tgacgctttt gctagtagga
     1021 gtggcagtat tggctggatt attgatgtgg cgtaagaaag cgcgcatatt tacagcgctc
     1081 ttacttgttt tttcactggt catcacgtct gttgggatct atggaatgca agaagttgta
     1141 aaattttcaa cacgactaaa ttcaaattcg acattttcag aatatgaaat gagtatcctt
     1201 gtcccagcaa atagtgatat tacggacgtt cgtcagctta ctagtatcct tgctccagcc
     1261 gaatacgacc aagataacat caccgcttta ttggatgaca tatccaaaat ggaatctact
     1321 caactagcaa ctagccccgc gacctcttac ctgacagcat atcaatctat gttgaatggc
     1381 gagagtcaag cgatggtgtt caacggagtt tttaccaata ttttagaaaa tgaagatcca
     1441 ggcttttctt caaaagtgaa aaaaatatat agtttcaaag tgactcagac tgttgaaaca
     1501 gctactaagc aggtgagtgg agatagcttt aatatctata ttagtggtat tgatgcttat
     1561 ggaccgattt ctacggtctc tcgttcagat gtcaatatca ttatgactgt caatcgtgcg
     1621 acacataaga ttttattgac aactactcca cgagattcat acgttgctat cgcagatggc
     1681 gggcaaaatc aatacgataa actaacacat gctggtatct acggtgtcaa tgcttctgtg
     1741 cacaccttag aaaatctcta tgggattgac attagcaatt atgtgcggtt gaacttcatt
     1801 tccttccttc aattaatcga cttggtgggt ggaattgatg tatataacga tcaagaattt
     1861 acaagtttac atgggaatta tcatttccct gttggacaag ttcatttaaa ctcagaccaa
     1921 gcattaggct tcgttcgaga gcgctactct ttaacagggg gtgacaatga ccgtggtaaa
     1981 aaccaggaaa aagtgattgc tgccttgatt aaaaagatga gtacgccaga gaatctaaaa
     2041 aattaccagg caatcctatc tggattggaa ggctcaattc aaacggattt gagcttagaa
     2101 acgattatga gtttagtgaa tacccaacta gaatcaggaa cacaatttac agtagagtca
     2161 caagcattga caggaacagg acgctcagac ttatcttctt atgcgatgcc tggatcacaa
     2221 ctttatatga tggaaattaa ccaagatagt ctggagcaat caaaggcagc gattcagtcc
     2281 gtacttgttg aaaaataaag attttaggag aaaatatgaa caatcaagaa gtaaatgcaa
     2341 tcgaaatcga tgttttattc ttactaaaaa caatttggag aaagaaattt ttaattctct
     2401 taactgcagt gttgactgcg gggttggcat ttgtctacag tagtttttta gtgacacctc
     2461 aatatgactc cactacccgt atctatgtag tgagtcaaaa tgttgaagcc ggtgcgggct
     2521 tgactaacca agagttacaa gcgggtacct atttggcaaa agactatcgg gaaattatcc
     2581 tatcacaaga tgtattgaca caagtagcaa cggaattgaa tctgaaagag agtttgaaag
     2641 aaaaaatatc agtttctatt cctgttgata ctcgtatcgt ttctatttct gtgcgtgatg
     2701 cggatccaaa tgaagcggca cgtattgcaa atagccttcg cacctttgca gtgcaaaagg
     2761 ttgttgaggt caccaaggta agcgatgtga cgacacttga agaagcagtc ccagcggaag
     2821 aaccaaccac tccaaataca aaacgaaata tcttgcttgg tttattagct ggaggtatct
     2881 tggcaacagg tcttgtactg gttatggagg ttttggatga ccgtgtaaaa cgtcctcagg
     2941 acatcgaaga ggtaatggga ttgacattgc taggtatagt accagattcg aagaaattaa
     3001 aataggagaa caatatggcg atgttagaaa ttgcacgtac aaaaagagag ggagtaaata
     3061 aaaccgagga gtatttcaat gctatccgta ccaatattca gcttagcgga gcagatatta
     3121 aggttgttgg tattacctct gttaaatcga atgaaggtaa gagtacaact gcggctagtc
     3181 tcgctattgc ctatgctcgt tcaggttata agaccgtctt ggtggatgca gatatccgaa
     3241 attcagtcat gcctggtttc ttcaagccaa ttacaaagat tacaggtttg acggattacc
     3301 tagcagggac aacagacttg tctcaaggat tatgcgatac agatattcca aacttgaccg
     3361 taattgagtc aggaaaggtt tctcccaacc ctactgccct tttacaaagt aagaattttg
     3421 aaaatctact tgcgactctt cgtcgctatt atgattatgt tatcgttgac tgtccaccat
     3481 taggactggt aattgatgca gctatcattg cacaaaaatg tgatgcgatg gttgcagtag
     3541 tagaagcagg caatgttaag tgctcatctt tgaaaaaagt aaaagagcag ttggaacaaa
     3601 caggcacacc gttcttaggc gttatcttga acaaatatga tattgccact gagaagtata
     3661 gtgaatacgg aaattacggc aaaaaagcct aatttctcag ataacataag tttgataagt
     3721 aggtattaat atgattgata tccattcgca tatcatattt ggtgtggatg acggtcccaa
     3781 aactattgaa gagagcctga gtttgataag cgaagcttat cgtcaaggtg ttcgctatat
     3841 cgtagcgaca tctcatagac gaaaagggat gtttgaaaca ccagaaaaaa tcatcatgat
     3901 taactttctt caacttaaag aggcagtagc agaagtttat cctgaaatac gattgtgcta
     3961 tggtgctgaa ttgtattata gtaaagatat cttaagcaaa cttgaaaaaa agaaagtacc
     4021 aacacttaat ggctcgtgct atattctctt ggagttcagt acggatactc cttggaaaga
     4081 gattcaagaa gcagtgaacg aaatgacgct acttgggcta actcccgtac ttgcccatat
     4141 agagcgttat gatgctctgg catttcagtc agagagagta gaaaagctaa ttgacaaggg
     4201 atgctacact caggtaaata gtaaccatgt gttgaagcct gctttaattg gcgaacgagc
     4261 aaaagaattt aaaaaacgta ctcgatattt tttagagcag gatttagtac attgtgttgc
     4321 tagcgatatg cataatttat atagtagacc tccgtttatg agggaggcgt atcagcttgt
     4381 aaaaaaagag tatggtgagg atagagcgaa ggctttgttc aagaaaaatc ctttgttgat
     4441 attgaaaaat caagtacagt aacctcatag aaatagtgga ggagctatga atattgaaat
     4501 aggatatcgc caaacgaaat tggcattgtt tgatatgata gcagttacga tttctgcaat
     4561 cttaacaagt catataccaa atgctgattt aaatcgttct ggaattttta tcataatgat
     4621 ggttcattat tttgca
//
LOCUS       DBNFCO010000106         4604 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.106, whole genome shotgun sequence.
ACCESSION   DBNFCO010000106 DBNFCO010000000
VERSION     DBNFCO010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4604
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.106"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            74..2398
                     /gene="hsdR"
                     /locus_tag="AC1PIV_001799"
     CDS             74..2398
                     /gene="hsdR"
                     /locus_tag="AC1PIV_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0015666 - restriction
                     endodeoxyribonuclease activity [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="EcoAI/FtnUII family type I restriction enzme
                     subunit R"
                     /protein_id="HIP6612783.1"
                     /translation="MVVFIKSKKEMSEEDIKANFITPAILSKGWKNGEQIAYEEYFTD
                     GRIEVRGDKGRRKEGKKSDYALYYQFGQRIAIVEAKDNKHSIRAGLQQAIEYGEILDV
                     PFVYSSNGDGFVEHDRITRQERELSLEEFPTRDELFERLKAEKEMAPEVSKAITTPYY
                     TDAFSIKKPRYYQQIAINRTIEAVASGQNRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFKPFEKVMTKITSKLLNAPEKLNSFEIYLGLYQQLMGE
                     DGTETHYQKFDKNFFDLIVIDEAHRGSAKEDSNWRKVIEYFSSATQIGMTATPKETKE
                     VSNMEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPENGKVDAKGQLIED
                     RYYGRKDFDKTIIIDDRTRKVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMREAFVN
                     ENQDLVREDYRYVMQVTGDNPEGKAQLDNFMDVNSKFPAIVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPEKGKEFFTIIDFRNVTNLFADPGFDGEPAKILD
                     PNLKTGQDSTSFTVGDPIEKYRVADRKVDILNSTVQVLDENGKLVTESLTDYTRKNIL
                     GTYATLTDFITAWHSADKKKVILEELYKKGVYLDAIREAENISEQEIDDFDLLLKLAY
                     GQKSLTKTERIRNVKQSGYLFKYSEEARAVLEVLLDKYMDKGIGELESIETLKLPEFH
                     VYGTPSKIVNTYFGNRKHYLEVIKELEEKLFAVA"
     gene            2411..3874
                     /locus_tag="AC1PIV_001800"
     CDS             2411..3874
                     /locus_tag="AC1PIV_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HIP6612784.1"
                     /translation="MSITSFVKRIQDITRNDAGINGDAQRIEQMSWMLFLKIYDSREL
                     DWELEEEEYESIIPEELKWRNWAHAEKGEQVLTGDDLLEFVNNKLFKELKELEITPNM
                     PIRKSIVKSAFEDANNYMKNGVLLRQMINVIDEVDFNSPEDRHSFNDIYEKILKDIQS
                     AGNSGEFYTPRAATDFIAEMLNPQLGETMADLACGTGGFLTSTLNHLGQQRKTSEDVQ
                     KYNQAVFGIEKKAFPHLLAVTNLFLHEIDDPKIIHGNTLEKNVRDYTEDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVEEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPEGYKN
                     FSKTKPMRNDHFNPVREWWKNRQEILEGNFYKSKSFRPDELASLNYNFDQCGFPKEEE
                     EILEPLELIQNYQQERAVLNKKIDTVLAEILEILEEK"
     gene            3874..>4604
                     /locus_tag="AC1PIV_001801"
     CDS             3874..>4604
                     /locus_tag="AC1PIV_001801"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HIP6612785.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQDPNDEPASELLKRIKEEKEKLI
                     SEGKVKRDKKETEFFRSDDGKPYEKLADGTVKKVEVPYEIPDSWEWVRLRNLGVITSG
                     GTPKSSESTYYDGNITWITPADMGKQQNNKLFATSSKKITELGVQKSSAQLISKNSIV
                     YSSRAPIGHINIVNYDFTTNQGCKSVTPILVNLDFMYWILQFRTKDIILRSSGTTFKE
                     ISASGFGDTLLPLPPLAEQKRIVAH"
BASE COUNT         1630 a          676 c          961 g         1337 t
ORIGIN      
        1 tataatagaa atatagtttg ttctgataat cttattatcc tgaagttatt attcatactg
       61 aaagaggaaa attatggttg tatttatcaa atctaaaaaa gagatgagtg aagaagacat
      121 taaagcaaac tttattacac cagctatttt gtcaaaaggc tggaaaaatg gagaacagat
      181 tgcttatgaa gaatatttca cagatggtcg aatagaagtt cgaggtgata aaggacgtcg
      241 aaaagaggga aaaaaatcag attacgctct ctattatcaa tttggacagc gaattgcaat
      301 cgttgaagct aaggataata agcatagtat tcgtgcaggt ttacaacaag cgattgaata
      361 tggtgaaatt ttggatgttc ctttcgttta ttcctcaaat ggtgatgggt ttgttgagca
      421 tgaccgaatt actagacaag agagggaact ctctttagaa gagtttccaa cccgtgatga
      481 attatttgag cgattaaagg ctgaaaaaga aatggcacca gaggtttcga aagcaataac
      541 aactccttac tatacagatg ctttttcgat taagaaacca cgctattatc agcaaattgc
      601 aattaatcgt acaattgagg cagttgcaag cgggcaaaac agagtcatgt ttgtaatggc
      661 aacaggtact ggaaaaacct ttatggcttt tcaaattatt caccgactta ggaaagccgg
      721 attagcaaag cgtgtcttgt ttttagcaga caggaatatt ttagttgacc aaacaatggc
      781 agaagatttc aagccatttg aaaaagtgat gactaaaatc acatcaaaat tgctgaatgc
      841 gccagaaaaa ttaaattctt ttgaaatata cttaggtctt tatcagcaat taatgggaga
      901 agatggaacc gaaactcact atcaaaaatt tgataaaaat ttctttgatt tgatagtgat
      961 tgatgaagct catagaggtt cagcaaaaga agatagtaat tggcgtaaag tgattgagta
     1021 tttttcatcg gcaacgcaaa ttggtatgac tgcgacacca aaagaaacta aagaagtttc
     1081 caatatggag tattttggtg agccaattta tacttatagc ctgaagcaag ggatagagga
     1141 tggatttctc gctccatatc gagttatgcg agtcaatcta gatgtggacg tagatggcta
     1201 tcgtccggaa aatggaaaag ttgatgctaa gggacagctt atcgaagata ggtattatgg
     1261 tcgcaaggat tttgataaga caattatcat tgatgatcgt acacgaaagg ttgcaaaatt
     1321 tgtttcagat tatatgaaac aaaataatgc acgctttgac aaaacaattg tattttgtgt
     1381 tgatattgat catgccgaac gtatgcgtga agcatttgtc aacgaaaatc aggatttggt
     1441 acgggaggac tatcgttatg ttatgcaggt gacaggtgac aatcctgaag gaaaagccca
     1501 actagataat tttatggatg ttaactctaa gtttccggcg attgtgacaa cttctaaact
     1561 tttaaccaca ggtgttaatg caaaaacttg tcgattgatt gtattagatt caaatattca
     1621 atcaatgaca gaatttaaac agattattgg tcgtggaaca cgtttatatc ctgaaaaagg
     1681 gaaagagttt ttcactatta ttgattttag gaatgtgaca aatctatttg ctgatcctgg
     1741 atttgatggt gagccggcga aaatattaga tcctaatctg aaaactggac aggattcaac
     1801 atcatttaca gtaggtgatc ctatagaaaa atatcgagtt gcggatagga aagtggatat
     1861 tctcaattcg acagttcaag tcttggatga aaatgggaaa ttagtaactg agagtctaac
     1921 agattataca cgtaaaaata ttttaggaac atatgcgaca ttaaccgatt ttattactgc
     1981 atggcattca gcagataaga aaaaagttat tttagaagaa ctctataaaa aaggtgtata
     2041 tctggatgca attcgtgaag cagaaaatat ttcggagcaa gaaatcgatg attttgattt
     2101 acttttgaaa ctggcatacg ggcagaaaag tttgactaaa accgagcgaa tcagaaatgt
     2161 gaaacaaagt ggatatctat ttaaatacag cgaagaagcg cgtgctgtat tagaggtttt
     2221 actagataag tatatggata agggaatcgg tgagcttgaa agtatcgaaa ctttaaagtt
     2281 accagaattt catgtttatg gtactccttc caagattgtt aatacctatt ttggaaatag
     2341 aaaacattac ttagaagtaa ttaaagaatt agaagaaaag ctatttgctg tagcttaatg
     2401 agaggaaaaa atgtcaatta catcatttgt taaacgaata caagatatta ctcgaaacga
     2461 tgcagggata aatggtgatg cccagagaat tgaacaaatg tcttggatgc tatttttaaa
     2521 aatctatgac agtcgagagt tagattggga gttggaggaa gaagaatacg agtcaattat
     2581 tcccgaggag ttgaagtggc gaaactgggc tcatgctgag aagggtgagc aggtcttgac
     2641 tggagatgac ttacttgagt ttgtgaataa taaattgttc aaagagttga aagaactcga
     2701 aatcactcca aacatgccaa ttcgcaaatc aattgtaaaa tctgcttttg aagatgctaa
     2761 caactatatg aaaaatggag ttcttctgcg gcaaatgatt aatgtgattg acgaagttga
     2821 ttttaacagt ccagaagatc gtcactcatt taatgatatt tatgagaaga ttctcaaaga
     2881 tattcaaagt gcaggaaatt ctggtgaatt ttacacacca cgtgcagcaa cagattttat
     2941 tgctgaaatg ctcaatcctc aattagggga aacgatggca gatttagcat gtgggacagg
     3001 tggtttcttg acatctacct taaatcattt aggccaacag cgaaagacta gcgaagacgt
     3061 tcaaaaatac aatcaagcag tttttggtat tgagaaaaag gctttccccc acctattagc
     3121 ggtgacaaat ttattcttgc atgaaattga tgatccgaaa atcatccacg ggaatacgtt
     3181 ggaaaaaaat gtgagggatt acactgagga tgaaaagttc gatatcatca tgatgaatcc
     3241 tccatttggt ggttctgaac ttgaaacaat aaaaaataat tttccagcag agttacgcag
     3301 ctctgaaaca gcagatttgt ttatggctgt tattatgtat cgacttaaag aaaatggtcg
     3361 tgttggtgta attctaccag atggattcct ctttggtgaa ggagtaaaaa cacgactaaa
     3421 gcagaaattg gttgaggagt ttaatcttca cactattatt cgcttaccac atagcgtatt
     3481 tgctccatat acaggaattc atacgaatat tctctttttt gataagacga aaaaaacaga
     3541 agaaacttgg ttttacagat tggatatgcc agaaggctat aaaaatttct ctaaaactaa
     3601 accaatgaga aacgatcact ttaatcctgt tcgcgaatgg tggaaaaatc gacaagagat
     3661 tttagaaggg aatttctaca aatctaaatc gtttagacca gatgagttag ctagtttaaa
     3721 ctataatttt gatcaatgcg gttttccaaa ggaagaggaa gaaattttag agccacttga
     3781 acttatccaa aactatcagc aagaacgagc tgtcctaaat aaaaaaattg atactgtttt
     3841 ggcggaaatt ttagaaattt tggaggagaa ataatgactc ctgaacaact gaaagcaagt
     3901 atcctgcaaa gagcgatgga gggtaagctt gttccgcaag acccaaatga tgagcctgca
     3961 agtgaacttt tgaaacgtat caaggaagag aaagagaagt tgatttcgga aggaaaagtc
     4021 aagcgagata aaaaggaaac agaatttttt cgtagtgatg atgggaaacc ttatgagaag
     4081 ttagctgatg ggactgttaa aaaagttgaa gtaccttatg aaattccaga tagttgggag
     4141 tgggtgaggt taagaaattt aggagttatt acttcgggag gcacaccgaa atcttctgaa
     4201 tctacttatt atgatgggaa tatcacttgg ataactcctg cagatatggg taaacagcaa
     4261 aacaataaat tatttgccac ctcatcaaaa aaaattaccg aattaggcgt acaaaaatct
     4321 tctgctcaac taatttcaaa aaactctatt gtttattcta gtcgagctcc aataggacat
     4381 ataaacattg ttaactatga ctttactaca aatcaaggtt gtaaatccgt aacgccaata
     4441 ctagtaaatt tagattttat gtattggatt ttgcaatttc gaacaaaaga tattattcta
     4501 cgatcatcag gtacgacatt taaggagatt tctgcttcag gttttggaga tacacttctc
     4561 ccccttcccc cgcttgccga acaaaaacgg attgttgctc acat
//
LOCUS       DBNFCO010000107         4593 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.107, whole genome shotgun sequence.
ACCESSION   DBNFCO010000107 DBNFCO010000000
VERSION     DBNFCO010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4593)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4593)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4593
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.107"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            51..1601
                     /gene="guaA"
                     /locus_tag="AC1PIV_001802"
     CDS             51..1601
                     /gene="guaA"
                     /locus_tag="AC1PIV_001802"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HIP6612786.1"
                     /translation="MTKQDVQKIIVLDYGSQYNQLISRRIREFGVFSELKNHKITAEE
                     VRAINPIGIVLSGGPNSVYAENAFDIDPEIFELGIPILGICYGMQLITHKLGGKVVPA
                     GEAGNREYGQSNLQLKTESALFAGTPEEQLVLMSHGDAVTEIPADFHLVGLSADCPYA
                     AIENTERRIYGIQFHPEVRHSVYGNDILKNFAFGICGAKGDWTMENFIETEIEKIRQT
                     VGDKKVLLGLSGGVDSSVVGVLLQRAIGDQLTCIFVDHGLLRKNEGDQVMEMLGGKFG
                     LNIIRVDAAKRFLDLLAGVSDPEKKRKIIGNEFVYVFDDEASKLTDVEFLAQGTLYTD
                     IIESGTDTAETIKSHHNVGGLPEDMQFKLIEPLNTLFKDEVRALGTALGMPDEVVWRQ
                     PFPGPGLAIRVMGEITEEKLQTVRESDAILREEIAKAGLDRDVWQYFTVNTGVRSVGV
                     MGDGRTYDYTIAIRAITSVDGMTADFAKLPWDVLQKISVRIVNEVDHVNRIVYDITSK
                     PPATVEWE"
     gene            complement(1776..2825)
                     /gene="mcrC"
                     /locus_tag="AC1PIV_001803"
     CDS             complement(1776..2825)
                     /gene="mcrC"
                     /locus_tag="AC1PIV_001803"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-methylcytosine-specific restriction
                     endonuclease system specificity protein McrC"
                     /protein_id="HIP6612787.1"
                     /translation="MIPVQNIYYMLSYAFKILHEQEYKRIATEEFKNAADLLAEIMII
                     SLSIQVKRGLGREYRSQTESLSALKGKINISESLTPPNWRRKQLVCQYDDFSLDSRMN
                     RIIKASIEILLKADISRDRKKKLRKLLVFFGEVSKINLHSINWNLQYNRNNQSYQLLM
                     SICYLVVNGLIHTEREGNKKLMNFLDERRESLLYEKFILGYYKKHYPQIQVTASQIPW
                     ALDDGFGEMLPIMQSDIYLKYKDTILIIDAKYYSSNTQIRFDKRTLHSNNLYQIFTYV
                     KNQAYRLSDSNDTVAGMLLYAKTDIDIQPNQVYQMHGNRISVKNLDLNLPFASIAEQL
                     DDIITSHFASPPKLY"
     gene            complement(2822..4519)
                     /locus_tag="AC1PIV_001804"
     CDS             complement(2822..4519)
                     /locus_tag="AC1PIV_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HIP6612788.1"
                     /translation="MDEQNQFNWVNFYKEFAWKLVDYKDNRAELVEKVKAIYTKTKIH
                     MPTLEKDNRLIDIDPFTIFGLFNKQIKEENRIKILTAIAELFNLQTEIPSSFESIPVL
                     MNQNATFYYFIGDRDENDIDDLWELFIAALTYSKEPTAEKKEKFSHYFDLAINKKGNG
                     NSKITMALYWIAPDFFLSLDSQNEAYVYESGEIPTDIVQKLPKMKSKISADDYFYISD
                     SMHHYLNSAESKLKDFKELSSMAWKYSKQINQEEKERSAGTISPLADETDTGNEIGSE
                     EVVEDSYTKNHFLSEVYMTEEEYDQLTSILQMKKNIILQGAPGVGKTFIAERLAFSLM
                     GKPDLERVMTIQFHQSYSYEDFIMGFRPSTSGFELRRGAFYTFCKKAESDKSHNYFFI
                     IDEINRGNLSKIFGELFMLIENDKRGKSLQLLYSDEQFSIPENLYIIGMMNTADRSLA
                     LLDYALRRRFAFFDIKPGFSTTGFKDYQANLKNEKFDRLISCVEKLNQAISTEEVLGD
                     SFCIGHSYFCGLSAEVLEQGLLEAIVEYELIPLLKEYWFDEPTKIYDWSSKLRSAIQ"
BASE COUNT         1309 a          905 c          882 g         1497 t
ORIGIN      
        1 ttaaactaac tactagtatt tgaatttttt tcaaaacgaa agggaaaaac atgacaaaac
       61 aagatgtcca aaaaattatt gtattggatt atggtagtca gtacaaccaa cttatttcac
      121 gtcgaattcg tgaatttggt gtcttttcag aattgaaaaa ccataaaatt acagctgagg
      181 aagtccgtgc tatcaatcca attggtatcg ttctttcagg tggaccaaac tctgtctacg
      241 cagaaaatgc ctttgatatt gatccagaaa tctttgaatt gggtattcct atcttaggga
      301 tttgctatgg tatgcagtta attacccata aattgggagg taaggttgtt cctgctggtg
      361 aggctggaaa tcgtgaatat ggtcaatcaa atcttcaact gaagactgaa tcagcgcttt
      421 ttgctggaac accagaagaa cagcttgtac tcatgagcca cggggatgct gtaactgaaa
      481 ttcctgctga tttccacctg gttggtcttt ctgctgactg cccttacgca gccattgaaa
      541 acacggaacg ccgtatctac ggtatccagt tccacccaga agttcgtcat tccgtatatg
      601 gaaacgatat tttgaaaaac tttgcgtttg gtatctgtgg agccaaaggc gactggacaa
      661 tggaaaactt catcgaaaca gaaattgaaa aaatccgcca gactgttggg gacaagaaag
      721 tcttgctcgg tttgtcaggc ggtgtagatt cgtctgttgt tggggtcctt cttcaacgtg
      781 ctattggtga ccaattgacc tgtatcttcg ttgaccacgg tcttcttcgt aagaatgaag
      841 gtgatcaggt tatggagatg ttgggcggta aatttggcct caatattatt cgcgtcgatg
      901 ctgctaagcg tttcttagac ctacttgctg gcgtatctga ccctgagaag aaacgtaaaa
      961 tcatcggtaa tgaatttgtt tacgtatttg acgatgaagc gagcaagttg actgatgttg
     1021 aattcctagc gcaaggaaca ctttataccg atattatcga gtcaggaacg gatactgctg
     1081 agacaatcaa atctcaccac aacgttggtg gtctgccaga agatatgcag ttcaagttga
     1141 ttgaaccgct caatactctc tttaaggatg aagttcgtgc cctcggtact gctcttggta
     1201 tgccggatga agttgtatgg cgccaaccat tcccaggacc aggccttgcc attcgtgtca
     1261 tgggtgaaat cactgaggaa aaacttcaaa ctgttcgcga atctgacgct atcttgcgtg
     1321 aggaaattgc aaaagcaggt cttgaccgcg atgtgtggca atatttcacg gttaatactg
     1381 gcgttcgctc cgtaggtgtc atgggagatg gtcgtaccta cgactacact atcgctatcc
     1441 gtgctatcac ttctgtcgat ggaatgacag ctgactttgc caaactacca tgggatgttc
     1501 ttcaaaaaat ctctgtccgt atcgtaaacg aagtcgacca cgtcaaccgc atcgtctatg
     1561 atataacaag taaaccacca gcaacagttg agtgggagta aattagtcca gtggactaat
     1621 ttacccgatg cctaaaaaca aaaaagtgtc gctgatctgg gaaatcaatt aaccagacgc
     1681 tccaaaatag gaaagagtct tataaaaaaa caatcaaaga gtagtttagt gctactactt
     1741 tgattgtttt tttgttttct agcttagagc tctaactagt acagttttgg aggggatgca
     1801 aaatgcgatg taatgatgtc atccagttgt tcagcaatac ttgcaaacgg caggtttaag
     1861 tccaaatttt tgacactaat ccggtttcca tgcatttggt agacctgatt aggttgaata
     1921 tctatatcgg ttttagcgta tagaagcatt cctgctactg tatcgtttga atctgacagg
     1981 cgataagcct ggtttttcac ataggtaaaa atttggtata gattatttga atggagtgtg
     2041 cgcttatcaa agcgaatctg tgtgttacta gaataatatt tagcatcaat aatcaatata
     2101 gtatctttat atttgaggta aatatcactc tgcatgatgg ggagcatttc tccaaaacca
     2161 tcatctagtg cccaaggtat ctgagaggcg gtaacctgta tttggggata atgcttttta
     2221 taatatccaa gaatgaactt ctcatatagc aaggattccc tccgctcatc aagaaaattc
     2281 atcaatttct tattcccctc cctctctgta tgaattaatc cattcaccac caaatagcag
     2341 attgacatta gtaattgata cgattgattg tttcgattgt attgtaaatt ccaattgatt
     2401 gagtgtagat taatttttga gacttctcca aagaaaacta agagttttct caatttcttt
     2461 ttcctgtccc tgcttatatc agcttttagc agtatctcaa tgcttgcttt gataatgcga
     2521 ttcattctac tgtcaagaga aaaatcatcg tattggcaaa caagttgctt tctacgccaa
     2581 ttcggaggtg ttaaagattc agagatattt attttacctt taagtgccga gagtgactcg
     2641 gtttgagaac gatactctcg accaagtcct cttttcacct gtatcgagag gctgattatc
     2701 attatttccg ccagtagatc tgcagcattt ttaaattctt cagtagcgat ccgtttatat
     2761 tcctgctcat gaaggatttt gaatgcgtag gatagcatat agtagatatt ttggacaggt
     2821 atcactggat ggcactcctt aacttactac tccaatcata aatttttgtc ggttcatcaa
     2881 accaatattc tttcaagagg ggaatcagtt catattcaac aatggcttct agcaaacctt
     2941 gttccagtac ttctgccgat aaaccgcaga agtaactatg cccaatacag aagctatctc
     3001 ccagtacttc ctctgttgaa atggcctgat ttagcttttc tacacaggaa atgagtctat
     3061 cgaatttttc gtttttcaga tttgcttgat aatctttgaa tcccgtagtt gaaaaacctg
     3121 gcttgatgtc aaagaaggca aagcgtcgtc tcagtgcata atcaagtagg gccaaactcc
     3181 tatctgcggt attcatcata ccgatgatat atagattttc tggaattgag aattgctcat
     3241 ccgagtagag gagctgtaaa gacttgcctc gtttgtcatt ttctatcagc ataaacaatt
     3301 caccaaaaat tttgctcaaa tttcccctgt ttatttcatc aataataaag aaataattat
     3361 gactcttgtc agactctgct tttttgcaga aagtatagaa tgcccctctt ctcagctcaa
     3421 agccacttgt cgaaggccta aagcccatga tgaagtcctc gtaggaatag ctttggtgaa
     3481 actgaattgt catgaccctt tctaaatctg gtttacccat taatgaaaat gctaggcgtt
     3541 ctgcaataaa cgtctttcca actcctggcg ctccttgtaa gatgatattc tttttcattt
     3601 ggagtatgga ggttaattga tcatactctt cttctgtcat atagacttct gataggaagt
     3661 gatttttcgt atagctatct tctactacct cttcactacc tatctcgttt ccagtatcag
     3721 tttcatcagc cagtggagaa attgttccag cacttctttc cttctcttct tgattgatct
     3781 gtttagagta tttccaagcc atggatgata attctttaaa atctttcagt ttgctctctg
     3841 cactgtttaa ataatgatgc atagagtccg agatataaaa ataatcatcg gcagaaattt
     3901 ttgacttcat ctttggtaat ttttggacaa tgtcagttgg aatctcccca gactcataca
     3961 catacgcttc attttgacta tctaagctca agaaaaagtc gggagcaatc caatacaagg
     4021 ccatcgtaat cttgctgttg ccatttcctt tcttgtttat agccaaatca aaatagtgtg
     4081 aaaatttttc tttcttctca gccgtaggct ccttgctata ggtcaaagca gcaatgaaaa
     4141 gttcccataa gtcatcaata tcattctcat cacgatctcc gataaaataa tagaaagtcg
     4201 cattctgatt catcagtact ggtatacttt caaaagagga tgggatttcc gtttggaggt
     4261 tgaataattc tgctatagct gtcagaattt taatgcgatt ctcctctttt atttgcttat
     4321 tgaagagtcc aaatatcgta aaaggatcaa tatctatcag tcgattgtcc ttttctaacg
     4381 tgggcatatg tatctttgtt ttggtataga tagcttttac tttctcaacc agctctgctc
     4441 tattatcttt atagtctact aatttccaag caaattcctt ataaaagttt acccaattga
     4501 attgattttg ttcatccata gtatcctcca acggtgttgt atctacacct attaaattat
     4561 gagttcgaat ttacctatat tttatcatta aac
//
LOCUS       DBNFCO010000108         4490 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.108, whole genome shotgun sequence.
ACCESSION   DBNFCO010000108 DBNFCO010000000
VERSION     DBNFCO010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4490)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4490)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4490
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.108"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            16..840
                     /locus_tag="AC1PIV_001805"
                     /pseudo
     CDS             16..840
                     /locus_tag="AC1PIV_001805"
                     /inference="COORDINATES: protein motif:HMM:NF017927.6"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
     gene            1033..1869
                     /locus_tag="AC1PIV_001806"
     CDS             1033..1869
                     /locus_tag="AC1PIV_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HIP6612789.1"
                     /translation="MMTSDIVSRAMMTRERTRGTTLLFFPSILLSIVYAIPATIFRLL
                     TFLELRQNSAFVEGRLVSSIRLTYLGELGFALLLQLFIGLSCFHLLELLRGDRQEFSL
                     KDSFSFLKTEWKKPICTTFLYYYLLLFIAGLPANLGATLFIKGFTMSSLMVLSPGAMA
                     ELAVHQPSQLMKIGAPIFLLGMIIYLFVYYTYSQVVFVLYDHLDNASYTGPLAVFRES
                     RFLMKGNYWQRIWLDLSFLGWFIGELLTLHLLSFFVTPYYHLSRTIFYEKLKKQRLSA
                     VE"
     gene            complement(1887..2762)
                     /locus_tag="AC1PIV_001807"
     CDS             complement(1887..2762)
                     /locus_tag="AC1PIV_001807"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamic
                     endopeptidase"
                     /protein_id="HIP6612790.1"
                     /translation="MKTEFINEKAQSAFNLNIVTSPIVAIILLLVGDSLGAVIFTPIS
                     FLLPFSETLSVSFELFAFAFISLMVILWARYIEKSPWVGLGFTKKGAGKDFLLGWGIG
                     AAMLTTCTLIMWGLGAIEFTSIQFSTKLVGEFIILILAWSIQGTTEEILTRGWMFSSL
                     SARHNIPIGIIVSSLFFTFLHLGNNAISLIPILDLTLFAVLACLIMLKTGNIWVIGGL
                     HAAWNCFQGNVFAFSVSGTDAGQAFIQIGITGPEWLSGGKFGVEGSVISLLVQGIMIC
                     WLVYDLYFKPKTSSL"
     gene            2885..3496
                     /locus_tag="AC1PIV_001808"
     CDS             2885..3496
                     /locus_tag="AC1PIV_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3885 domain-containing protein"
                     /protein_id="HIP6612791.1"
                     /translation="MELSQWLKSFQLKDNRLVGPFFYGTPLALRFEIGPADEAEELSR
                     AIYLERAYARAVELFEQASSEYDYVLLSLLRQEDRDIDTYLWHFSSKFNFNKVPESEL
                     IEVEDWTGDVLVFERYLFPVTDQDLNALLREIVKADHGGFNYLSSSVLFLSSQDNIIY
                     HCYDNRGVDIAVLADDKRLELFTDCHDLLLDYDMEEMERRVRG"
     gene            4137..4229
                     /locus_tag="AC1PIV_001809"
     CDS             4137..4229
                     /locus_tag="AC1PIV_001809"
                     /inference="COORDINATES: protein motif:HMM:NF028245.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HIP6612792.1"
                     /translation="MSVAEAFGLMFQFSTLLIVLLTFIFNNRKK"
     gene            complement(4244..>4490)
                     /locus_tag="AC1PIV_001810"
     CDS             complement(4244..>4490)
                     /locus_tag="AC1PIV_001810"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612793.1"
                     /translation="GILLFLGCQAVFDDVDKKLSNDFGLWYNSFGKGIERQLNPSIVF
                     FRFRETTSNSLPDCLNILKTGQMKITVNLLVHSVKVS"
BASE COUNT         1309 a          807 c          954 g         1420 t
ORIGIN      
        1 gaacaaacag ataggatgat aaccttgttt ttggcacctg ttttgatttc ttttctgtca
       61 ggagtggcag aatttggctt gaaacaaatc tgggggcaaa ctggtacttt ctcctggggc
      121 acaactattg tgaaagacgg tgttacttgg actcatcatt ttatttctgt tggcccgtca
      181 atcatatttg attttattgc acaatgttta attgtaacag cttgttttca actaataaga
      241 ctggtgagaa agcaaagaac caaggttagc tttacggagt gtttcacttt actagatggg
      301 gagaattttt taccagtttt tagtacgaca ttattgaaaa tgctggtctt gtatttagca
      361 agtttccctg ctgtttttgg aatgatattg ataggtttag ctttctatag tactattgtc
      421 atctttggtg ctcctattga ttatcagcct gatttttcag cttttttcag ttcgtcttat
      481 tttcaaacag gattaatact ggtatgtgta gggattattt gtagtttatt cgtaggatat
      541 gggctcagtc aggtcacttt tcttctctat gattatttgg aaaacaatac ctattcttca
      601 ccatttaaac tcttcagtta gagctggcag ttgatgaagg ggaataaatg gcgccgtttc
      661 ctcttggatt tatcttttgt tggctggttt attggagttc ttttgacgtt tgggtttttg
      721 ggactttacg tatatccata ctattggact tgtcagacta tattttatga agatttgaag
      781 gccaagaatc cattggtgtt ttcaacatat aaatcagtta tctcttccat agtagcctag
      841 ggagtatgga gataacaaat tattaggaat cccttcgtat tttggaggga ttttcctgtt
      901 tttaagagat gttctggaaa attaatggat aaagttttat actaatagta ggatggtaaa
      961 gtagtccgat gtagatataa tatttgcgac gtgactttat aaataaggag agaaaattgg
     1021 aggggaattg tgatgatgac gagtgatata gtatcaagag cgatgatgac tcgcgagcgg
     1081 acaagaggta caacactact attttttccc tccattttgc tatctattgt ttatgctata
     1141 ccagcaacaa tttttcgcct actaacattt ctagagctcc gtcaaaacag tgcttttgtg
     1201 gaggggcgat tggtatcttc aatcaggttg acctatttag gtgagttagg cttcgctctg
     1261 ttgttacagc tgttcatcgg tctgtcctgt tttcatttat tggaattgtt gagaggggat
     1321 agacaggagt tttctttaaa agatagtttt tcatttttaa agacagaatg gaagaagcct
     1381 atctgtacca cttttcttta ttattatttg cttcttttta tagctggact tccagctaat
     1441 ctaggggcta ctttatttat taaaggcttc acaatgagta gtttgatggt cttatctccg
     1501 ggggcaatgg cagagctggc agttcatcag cctagtcaat taatgaagat aggggctccg
     1561 attttcctgc taggaatgat tatttacctt tttgtctact atacctactc acaggttgtt
     1621 ttcgtcttgt atgaccattt ggataatgct agttatactg gtcccctggc tgtatttagg
     1681 gaaagtcgtt tcttgatgaa agggaactat tggcaacgta tttggttaga tttatccttt
     1741 ttaggttggt ttattgggga attattgacc cttcatctgt tatctttttt tgtgactcct
     1801 tactatcatt tatccaggac tattttctac gaaaaattga aaaaacaaag actgtcagct
     1861 gtagagtagc taacagtctt ttatgattat agggagcttg ttttgggctt gaaatagaga
     1921 tcgtaaacca accagcaaat cattatacct tggacaagca agctgatgac ggagccctct
     1981 acgccaaact ttccaccaga tagccactca ggaccagtga taccgatttg aataaaggcc
     2041 tgaccagcat cggtgccgct gactgagaaa gcaaaaacat tcccttggaa acagttccac
     2101 gcagcgtgta agccaccaat cacccaaatg ttgcctgttt tgagcataat gaggcaggca
     2161 agaacggcaa atagagttaa atccaaaatt ggaatgagtg aaatagcatt gtttccgagg
     2221 tggagaaatg tgaagaagag ggaagaaaca atgataccga taggaatatt atgtctagca
     2281 gaaagtgatg agaacatcca tcctcttgtt agaatttctt ctgtcgtacc ttggatagac
     2341 caggcaagga taaggataat aaattctccg actaattttg tagagaactg gatgcttgta
     2401 aattcaatcg cgcctaatcc ccacatgatg agtgtacaag tggtcagcat tgcagctccg
     2461 attccccacc cgagtagaaa atcttttcct gcaccttttt tagtaaaacc aagtcctacc
     2521 cacgggcttt tttcaatata ccgtgcccat aaaatgacca tcaggctgat aaaagcgaaa
     2581 gcgaacagtt caaaacttac agaaagggtc tcgctaaatg ggagtaaaaa gcttattgga
     2641 gtgaaaataa cagctcctag tgaatctcct actagcaaca aaataatagc tacaatagga
     2701 gaggtgacga tgttgagatt gaaagctgat tgagccttct cattgataaa ttcggttttc
     2761 ataggacctc cttttactag atactttact agttcactat tctatcatat ttttcaaaag
     2821 aagactagac ctaatttcct agtatatggt agaatagtac aaagctatat aaggagaata
     2881 gtatatggaa ttgagtcaat ggctgaagtc ctttcaactg aaagataatc gactagtggg
     2941 cccattcttt tatggcacac ctcttgctct tagatttgaa atcgggcctg cagacgaagc
     3001 agaagaatta tcaagagcaa tctatcttga aagagcctat gcacgtgcag tagaactttt
     3061 tgagcaggct agttcagaat acgactatgt gctcctttcg ctccttcgac aggaagatag
     3121 ggatatagac acctacctct ggcatttttc atcgaaattt aacttcaaca aggtccctga
     3181 gtctgagttg atagaagtgg aggattggac gggagatgtg ctagtctttg agcgctatct
     3241 ctttccagtt accgaccagg acctaaacgc tttgttgagg gagattgtca aagccgacca
     3301 tggaggtttt aactatctat caagttccgt tctcttccta tctagtcagg acaatatcat
     3361 ctatcattgc tacgataatc ggggagttga tattgctgtt ttagctgatg acaaacgttt
     3421 ggagctcttt acagactgcc atgacctcct tttggactat gatatggagg agatggagag
     3481 aagggtgagg gggtaggaaa ccattactaa aggtgatata ccatctctta gataaaagta
     3541 cttcacaagt gaatacaggt tcaaaaaaat ccacagtaaa acctgtggaa aatatggtag
     3601 aatagaacag tagaaaagtt ccaaaagtgg agcggaaatc tattttggga ggtggcaact
     3661 tcatttttga tggaaagtaa aactttctca tcaaaaaacg aggctgggca aaaagtccaa
     3721 agccacttct cagagttcgt gtcaacatct cagcgcagtg gttgtttggg tttaacagtc
     3781 cagtggactg ttaaaggttg gagataggat ttgcaaagca aatcacagca gttcgtgttt
     3841 cacactccaa atctgaccat tacgactgat gcgaacagag ttcgcttcat ctccaacctc
     3901 aaactgtctc ccagacagtt tgagctgtgc ggggggtggg agtgaaacag tctgggaata
     3961 gactgtttca gctcaacaac ttaaaacgaa aaattgttga cgaactcttt ttgacaagtt
     4021 gagttctttc ccactcccta aaagttgcac taattcgatt tttgaaaaat attgtttcaa
     4081 aaatctcatg tcgatgccag agacaatcag catctctatt gattttactc taactaatgt
     4141 ctgtcgcaga agccttcggg ctgatgtttc agtttagcac gttgctaatc gtgctactga
     4201 catttatttt taacaatcgt aaaaaataaa agacagccaa ccgctacgaa actttgaccg
     4261 agtgaactag caggttgact gtaatcttca tttgtcccgt ctttaaaatg ttcaaacagt
     4321 ctgggagact gtttgaggtc gtttctcgaa aacggaagaa aacgatactg ggattgagtt
     4381 ggcgctcaat cccttttcca aaactattat accacaaacc aaaatcgttt gacaattttt
     4441 tatctacatc atcaaaaacg gcttgacagc ctaagaaaag gagaatacca
//
LOCUS       DBNFCO010000109         4432 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.109, whole genome shotgun sequence.
ACCESSION   DBNFCO010000109 DBNFCO010000000
VERSION     DBNFCO010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4432
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.109"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(<1..719)
                     /locus_tag="AC1PIV_001811"
     CDS             complement(<1..719)
                     /locus_tag="AC1PIV_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009909823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3307 domain-containing protein"
                     /protein_id="HIP6612794.1"
                     /translation="MSFSVISSYLIQHPVLTALLIAHFLSDFTFQSQALADAKKLHLK
                     ALFMHLFIVAIPLLILALLTPIQNGDLFFQVWLSHLAIDYVKYFLNKHHWIKDSWEAG
                     AFLVDQLLHIISIIILYHTIGVNVASHSLWIEPNYLLLQILFILLISKPVNILFKLYF
                     SKYQVAEGEEEQTVTGAGALIGQLERLIMGIFLLLGQYTAIGLVFTAKSIARYDKISK
                     SQAFAEYYLIGSLFSIISVLV"
     gene            complement(723..1391)
                     /locus_tag="AC1PIV_001812"
     CDS             complement(723..1391)
                     /locus_tag="AC1PIV_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SatD family protein"
                     /protein_id="HIP6612795.1"
                     /translation="MNYIAIIGDIVNSKQTSNRSSIQERLKQQLNRINHSFAQDFASP
                     FTITKGDEFQALCKPNPYIFFIIDQIQLAFRDEVEIRFGIGLGEILTAIDPKLSIGAD
                     GPAYWEARKAIDFIHDNHDYGTSKIAFSSEYKQIDRVINPLLTSSDFIKAAWNRSQTD
                     LFETLISKKIYQEDFTQKPIAEKMKLSQSAFTKRLKSSGIKLYLRNRQTAMNLILQLS
                     QKEG"
     gene            complement(1585..3123)
                     /gene="ffh"
                     /locus_tag="AC1PIV_001813"
     CDS             complement(1585..3123)
                     /gene="ffh"
                     /locus_tag="AC1PIV_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HIP6612796.1"
                     /translation="MAFESLTERLQNVFKNLRRKGKISESDIQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAIGHEVIETLNPAQQIIKIVDEELTAVLGSETSEIIKSPKIPT
                     IIMMAGLQGAGKTTFTGKLANKLKQEENARPLLIAADIYRPAAIDQLKTLGQQIDVPV
                     FELGNQVPALEIVRQGLEQAKANHNDYVLIDTAGRLQIDQALMTELREIKEFAQPNEI
                     LLVVDAMIGQEAANVAREFNDQLAITGVILTKIDGDTRGGAALSVRHITGQPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASKEYDEKKSLELAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMAGNPALANLKVDEREIARKRAIVSSMTPAERENPD
                     LLTPSRRRRIANGSGNSFVEVNKFIKDFNQAKTMMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPDMNGMDMSALEDMMGGAGMPDMSQMFGGGLKGKIGEFAMKQAMKRQANKIKKAK
                     KKRK"
     gene            complement(3136..3468)
                     /locus_tag="AC1PIV_001814"
     CDS             complement(3136..3468)
                     /locus_tag="AC1PIV_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HIP6612797.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FQVSRQAVYDNIKRTEKLLEDYEMKLHMYSDYVVRSQIFDEILNKYPEDAYLKEKIAI
                     LTSIDNRE"
     gene            complement(3571..4269)
                     /locus_tag="AC1PIV_001815"
     CDS             complement(3571..4269)
                     /locus_tag="AC1PIV_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003076949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HIP6612798.1"
                     /translation="MKAAYITIHDKIKEQIDNGIWKIGQRLPSERDLADEFGVSRMTL
                     RQGITLLVEEGILQRKIGSGTYVASTRVQEKMRGTTSFTELVQLQGKTPSSKLLSYTR
                     TKPNEKEVEQLGLSRGEYVIRMERVRYADNVPVVYEVASIPERLIKNVPKEDVTNHFF
                     KTLMDNGYRIGTSKQTIFARLANEKVAQYLQISKNQAILALKQVSYLEDGQAFEFVNS
                     QYVGERFEFYLENN"
BASE COUNT         1262 a          875 c          857 g         1438 t
ORIGIN      
        1 aatactagga cactgatgat actaaatagc gaaccaatta aatagtattc agcaaaggct
       61 tggcttttgg atattttatc atagcgtgcg atggactttg ctgtaaatac cagtccgata
      121 gctgtgtatt gccccagaag cagaaaaatt cccattatga ggcgctccaa ttgaccaatc
      181 aaggctcctg cacctgtcac agtctgctct tcttctcctt ccgctacctg atatttgcta
      241 aagtagagtt tgaaaagaat attgacgggc ttgctgatca gaaggataaa aaggatttgc
      301 aggaggagat aatttggttc aatccagagt gagtgtgaag cgacattaac accgatagtg
      361 tgataaagaa tgatgattga gatgatatgg agcaattgat caactaggaa tgctccagct
      421 tcccaggagt cctttatcca atggtgtttg ttgagaaaat atttgacata gtcaatcgca
      481 agatggctca gccaaacttg aaaaaataaa tctccgtttt gaataggggt aagtaaggct
      541 aggataagaa gagggatagc aacaatgaaa aggtgcatga aaagagcttt caaatgaagc
      601 tttttagcat ccgccagtgc ttgactctgg aaggtaaaat cacttaaaaa gtgggcaata
      661 agcaaggcgg ttaaaactgg atgttgaata agatagctag aaataactga aaatgacatg
      721 ctttatcctt ctttctgact gagctggaga atcaaattca tggcagtttg acgattacgc
      781 aggtagagtt tgattccgct ggatttcaaa cgtttggtaa aggcgctttg actgagtttc
      841 attttctcag caattggctt ttgtgtgaaa tcttcttgat agattttttt ggagattaag
      901 gtctcaaaca gatccgtttg cgaacgattc caggcagctt tgatgaaatc gctagaagtt
      961 agcaaggggt taatcacacg atcgatttgc ttgtattcag atgaaaatgc aattttgctg
     1021 gtgccatagt catggttgtc atgaatgaag tcaatagcct tgcgtgcttc ccaataagct
     1081 ggaccatctg ctccaatact tagcttggga tcgatagctg ttagaatctc acccaaacca
     1141 attccaaatc gaatctccac ctcatcacga aaggctagtt ggatttggtc aattataaaa
     1201 aaaatataag ggttaggctt gcataaggct tgaaattcat ctccctttgt aatggtaaat
     1261 ggcgatgcga agtcctgagc gaaggaatga ttgattctat ttagctgctg ttttagccgc
     1321 tcttgaatac tagagcggtt tgaagtctgt tttgaattga caatatctcc tattattgcg
     1381 atataattca taacttatcc tctaatttct attatatttc cattataacg gacaatataa
     1441 agattgtcca ctaaaaagga catttttgaa tatttctgtt ataacggaaa gtgttggagt
     1501 ttgaaaatca tttttcctgc tttgctactt ctattttata ttgctatatc ttacttcttc
     1561 gaataaaaag taaaaaagaa gagattattt tctcttcttt ttggctttct tgattttatt
     1621 ggcttggcgt ttcatggctt gtttcatagc aaactcacca attttacctt tcaaaccgcc
     1681 tccaaacatt tgggacatat ctggcatacc agctcctccc atcatatctt ccagagcaga
     1741 catatccata ccgttcatgt ctggcatgtt tttagggaga ttatttgggt tgattcccat
     1801 ttgtttcatc attttgttca tgtcgcctga catgacaccc tgcatcatgg ttttcgcttg
     1861 gttgaaatcc ttgataaatt tattgacttc gacaaagcta tttccagaac cgttagcaat
     1921 acgacgacga cggcttggtg tcaacaaatc aggattttct cgttcggctg gtgtcataga
     1981 agatacgata gctcgttttc gtgcaatttc acgctcgtca actttcaagt tggcaagtgc
     2041 tgggttacca gccatacctg gaatcatctt cagcaggtct tccattggtc ccatattttg
     2101 aacttggtcc agctgatcaa tgaaatcgtt gaaatcaaag gtattctcac gcattttttc
     2161 agcgagttct agtgatttct tctcatcata ttctttgctg gctttttcaa tcaaggtcag
     2221 catgtcgccc atgcccaaaa tacgcgagga catacggtct gggtggaagg tttcaatatc
     2281 tgtgattttt tcaccagtac cggtgaattt gattggctga ccagtaatgt gacggacaga
     2341 caaggctgca ccaccacgtg tatcgccgtc aatcttggtc aaaatcacac cagtaatagc
     2401 cagttgatca ttgaactcac gcgcaacgtt ggcagcttcc tgaccaatca tagcatcgac
     2461 gaccaagagg atttcgtttg gctgagcaaa ctctttgatt tctcttagtt cagtcatgag
     2521 ggcttggtca atctgcaaac gacctgctgt atcgatcaga acgtagtcat tatgattagc
     2581 cttggcttgc tccaaacctt ggcgtacaat ctccagggca gggacttgat tgcctaactc
     2641 gaatacaggt acatcaattt gttgaccaag ggtcttcaac tggtcaatgg cagctggacg
     2701 ataaatatcg gcagcaatca agagtggacg ggcattttct tcctgcttga gtttattagc
     2761 caacttacct gtgaaggtcg ttttaccagc accctgcaat ccagccatca taatgatagt
     2821 tggaattttt ggtgatttga taatttctga agtttcagaa cctaatacag ccgtcaattc
     2881 ttcatcaacg attttgataa tttgttgagc ggggttcagg gtttcaatga cttcatgacc
     2941 gatagcacgt tcacgcacct tcttgataaa gtcttttaca actggcaagg caacgtcggc
     3001 ttctagtaag gccagacgaa tttccttagt tgcttcctga atatcactct cagaaatttt
     3061 tcccttacga cgcagatttt taaaaacatt ctgtaaacgt tctgttaagc tttcaaaagc
     3121 catatacttc tcctcttatt ctctattatc aatactggtt agaatagcga ttttttcctt
     3181 caaataagca tcttctggat acttgttcag tatttcatcg aaaatctggc tacgcactac
     3241 atagtcagaa tacatatgta gtttcatctc gtagtcttcc agtaattttt ctgttcgttt
     3301 aatgttatcg tagaccgcct gacggctgac ttgaaattct tcagcaatct cagccaaact
     3361 gtaatcatcg gcataataga gctcgatgta gttcatttgc ttgtctgtta gcaaggctgc
     3421 atagaattca aataaggcat tcattcggtt ggttttttca atttccataa acttcattat
     3481 atcaaaaatt ccatatttta taaataagaa aatccgtcat cactagaaag attacggatt
     3541 ttaaaaatgt tttacataat tatttttatg ttaattgttt tctaaataga attcgaaacg
     3601 ttccccaaca tactgactat ttacaaattc aaatgcttga ccatcctcga gataagatac
     3661 ctgttttagt gcgagaatag cctggttttt agaaatttgt aaatattgag ccactttttc
     3721 attggctaaa cgcgcaaaaa tagtttgttt gctcgttcca attcgataac cattgtccat
     3781 aagtgtttta aagaaatggt tggtaacatc ttcttttggg acatttttta tcaagcgttc
     3841 aggaatgctg gcaacctcat acacgacggg aacattatct gcatagcgga cccgctccat
     3901 tcgaataaca tactcgccac gggataaacc taattgttca acttcttttt cattaggttt
     3961 ggttcgtgta taggacaata atttgctgct tggcgtcttt ccttggagtt gtactaattc
     4021 agtaaaggaa gtcgtgcctc gcatcttttc ttgaacccgt gtactggcga cataagtacc
     4081 ggaaccaatc ttgcgttgta gaataccttc ttccactaaa agtgtgattc cttgacggag
     4141 cgtcatacga gaaacaccaa attcatctgc taaatcgcgt tcacttggta aacgttgacc
     4201 aattttccag attccgttat cgatttgttc cttaatttta tcgtgaattg tgatatatgc
     4261 tgctttcatt tatctagcct ttctcttctt tctagtttac caaaaataaa ggcgtttggc
     4321 taattcaggc cacactctat tggtaaaatt ctcctaggca aacaatgaag tcagattacc
     4381 taaaataaag tgagtaaaaa caataaaaat acgaacacta acatttttat ta
//
LOCUS       DBNFCO010000110         4344 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.110, whole genome shotgun sequence.
ACCESSION   DBNFCO010000110 DBNFCO010000000
VERSION     DBNFCO010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4344)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4344)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4344
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.110"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            30..215
                     /locus_tag="AC1PIV_001816"
     CDS             30..215
                     /locus_tag="AC1PIV_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612799.1"
                     /translation="MSQPVVPLTIPQSRRFEKKSRNDILMKIRLGKTEVTFFQSINPE
                     VMETILDKVLHYDHPTQ"
     gene            196..483
                     /gene="tnpB"
                     /locus_tag="AC1PIV_001817"
     CDS             196..483
                     /gene="tnpB"
                     /locus_tag="AC1PIV_001817"
                     /inference="COORDINATES: protein motif:HMM:NF017528.6"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HIP6612800.1"
                     /translation="MTIRLSDLGQVFLVCGKTDMRQGIDSLAYLVKSQFNLDPFSGQV
                     YLFCGGRKDRFKALYWDEQGFWLLYKRFENGKLAWSNNEEEVKALTSEQVD"
     gene            600..806
                     /locus_tag="AC1PIV_001818"
     CDS             600..806
                     /locus_tag="AC1PIV_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
                     /protein_id="HIP6612801.1"
                     /translation="MDELLAIIKQQTSTIEQLTNELTLLREQVDYLRQKLYGKSSEKV
                     VYQPGQLSLFGEESLPEEEADLPS"
     gene            760..2092
                     /gene="tnpC"
                     /locus_tag="AC1PIV_001819"
                     /pseudo
     CDS             760..2092
                     /gene="tnpC"
                     /locus_tag="AC1PIV_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002941577.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
     gene            2296..3117
                     /locus_tag="AC1PIV_001820"
                     /pseudo
     CDS             2296..3117
                     /locus_tag="AC1PIV_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(3477..4344)
                     /locus_tag="AC1PIV_001821"
                     /pseudo
     CDS             complement(3477..4344)
                     /locus_tag="AC1PIV_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730292.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_function: GO:0009009 - site-specific recombinase
                     activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
BASE COUNT         1354 a          787 c          950 g         1253 t
ORIGIN      
        1 gttataaaaa acaaactgga ggattcatta tgtcacagcc cgtcgtccca ttgactattc
       61 cccaatctcg ccgctttgaa aagaaaagca gaaacgatat tctgatgaaa attcgtctcg
      121 gaaaaacgga agtcacattc ttccaatcta tcaaccctga agtaatggaa acaatcttgg
      181 ataaggtact gcattatgac catccgactc agtgatttag gtcaagtctt cttggtctgt
      241 gggaaaacgg atatgcgtca ggggattgac tctctcgcct atcttgtcaa aagtcaattt
      301 aatctggatc ccttttcagg tcaggtctat ctcttctgcg gaggtcgaaa agaccgattc
      361 aaagctcttt actgggatga acagggattt tggttattgt ataaacgttt tgaaaatggg
      421 aaattggcct ggtcaaacaa tgaagaagaa gtcaaggctc taacttccga acaagtagat
      481 tagctcatga aaggattttc tatcattcca aaaataaatg tttcaaaaag tcgtgatttc
      541 tattgaaatc atggcttttc tttgtgtata atgagataaa aagaaggagg agcgagcgta
      601 tggatgagtt gttggcaatt attaaacaac agacctcaac gattgaacaa cttaccaatg
      661 agctaaccct ccttcgagaa caggttgact atctgagaca gaaactctac ggaaaatcat
      721 cagagaaagt tgtgtatcaa cccggtcagc tgagcttgtt tggggaggaa agcctccctg
      781 aagaagaagc tgacttaccc agttgaaaca gagatcatca cttataaacg caagaaaact
      841 aagggagttc gtcaggctat ttttagtcag ttcactccag agatagtgca tcacgaattg
      901 cagggcgaag actgcacttg tccagactgt catggtcagt tgaaagagat tggctcagct
      961 gttcaacgac aagagttggt cttcattcct gcacaattaa agcggattga ccatgttcaa
     1021 cacgcataca agtatcaggc atgtagccag aagaatctga gcgataagat tatcaaggct
     1081 cccgttccta aggcaccttt ggcacacagc ttgggttcag cctctatcat cgctcacacc
     1141 attcatcaga agttcaattt gaaggtgcca aattaccgtc aggaagagga ttggcataag
     1201 cttggcctgc ccatcagtcg gaaggaaata gccaactggc atatcaagtc tagtcagtat
     1261 tatttcgagc cgatttacaa cctgttgcac gagaaattgt tggagcagcc tattctccat
     1321 gcggatgaga ccgcctacaa ggtcttagaa aatgatggtc agttgacctt cttgtctggg
     1381 aaacatgagg aaaatggaat taccctctat catcatgaca aacgacggag tggcttggtt
     1441 gtggaggagg ttcttgggga ctatgcgggc tacgtacatt gtgacatgtg gagtgcttat
     1501 cgtcaattag acaaggctca gctggttggt tgttgggctc ccgtcaaacg aaagttcttt
     1561 gaggcgactc ctaagaagac agacaagact tctttaggag tccaagggct tagcctattg
     1621 cgaccgcctg tttgccttgg agagttgact gggctgactt gtctagcgag gagcgactgc
     1681 ataaacgctg gctcccttga tggacgagtt ctttgactgg tgtcgtgagc aatctgtttt
     1741 gccaggctcc aaattgggta ctgctttgga gtatagcctc aaatacgaaa ccaccttccg
     1801 aaccgttctc tcggatggtg acttggtcct gtctaacaac atggctgaaa gggctatgaa
     1861 gaccttggtg atgggcagaa aaaattggtt gttctcccaa agttttgagg gagccaagtc
     1921 gacagctatc attttgagtc ttttggaaac ggccaagagg cacgaacttg atacagagaa
     1981 atatatgacc tatcttctag acaatctacc taacgaggaa acactcgcta aaaaagaagt
     2041 tctagaggct tatttgccat gggagaagaa aattaagaga gcatgtcaat agaaaaaggt
     2101 tccagagtca acaggacttt ggagcctttt caatatacct tattattggg cggttacaaa
     2161 gtagcctagg aaacgaagcc gaagatagaa ctggagttgg agttcatcaa ggcaagttga
     2221 caacggataa ttttgatttt cgaagagtat caataaaaat caaagatagc aagtctaagc
     2281 tacttatgaa agttctataa tgaagtcaaa cgtgggacaa ctttacaaca agtgcgaaaa
     2341 gggctgtaca aaaaagtcta ttctgctgac tatgcacaaa cggtataccg aactaatcga
     2401 aaacgatcgg taaaaaagat aatcctaacg aaagaattga aagagaaaat tttacactat
     2461 actaagcaaa aattttctcc tgaaatgatg gttaagaaga agaaaatgaa agtgggtatt
     2521 tcaaccattt actattggtt tcatcatggc catttaggat tgacgaaagc agatatgctt
     2581 taccctagaa aagggaaaag ggtcaagaag caagctagtc ctaactttaa accagcagga
     2641 aaatctatcg aagaacgtcc tgacgttatt aatcttcgct tggaaaacgg tcattatgaa
     2701 attgatacag ttctactaac cagagggaaa aatcattgcc tcttagtctt aaccgaccga
     2761 cgaagcaggc accaaatcat acgattaatt ccaaacaaaa ccgccgaatc ggtcaatcag
     2821 gcactggagg gaatcttgag ggaacatcgt atcctgtcta taactgtaga taatggtaca
     2881 gaatttagtc gtctggctga agtgtttcct gaggagtata tctactatgc gcatccctat
     2941 tcttcatggg agaggggaac gaatgaaaat cacaatcgat tgattcggag atggttacct
     3001 aaaggaacca agaaaacgac tccaaaagaa gtcgctttta tcgaacattg gatcaacaac
     3061 taccctaaaa aatgcttgga ctacaagtcg ccgagtgaat ttcttatggg tggctaattt
     3121 caacttgaaa tttggggtct aagctactta taacatttga aaccttaatt tataagtttg
     3181 agttgaggat tgtggatttc aagcagctgt tttcttctaa aaaaataaca aaatcgaaac
     3241 ggtccatatc cactttgagt ggtagttggc tatttttgat tttaaatgag tatcacaccc
     3301 catcgtccca ttgactgttc cccaatctcg ccgctttgag aagaaaggca gaaatgatat
     3361 tctgatgaaa attcgtctcg gaaaagtgga agtcacattc tttcactcta tcaaccaaga
     3421 aacattagaa acaatcttag ataaggtact attttatgac catccgactc agtgatttag
     3481 gtcaagtcta cttggtttgc gggaagtagt ggtgtgattt ggttaagagg attatgctca
     3541 cttagaattt ctacctgctt gctttgagag acatgagtgt agatttgtgt tacattgatg
     3601 ttactgtggc ccagtaaatg ttgtatttgt cgaatatcga cgccattatc aagcaacata
     3661 gttgcaaaac tatgtcgaaa catatgtgga gtgatatgtt ttttcagttg tagcgagtga
     3721 gaaatatttt tcagacttaa gcgcacactt tgttctttaa gatgatcatc gttttcacac
     3781 tggtaaatag ataactagaa tgactacaat gatgcgctat atagtcttca agtaacgaaa
     3841 gtgttttatc gtttccaata tagagtagtc gcactttctt tccttttccg agtatttgaa
     3901 tggttctatt ttccaaattg atattatcaa gttttaaatt acataattca gagatgcgta
     3961 gaccagttga taaaagtagc gagataagga gtagatttcg catagctttc cgattagaat
     4021 gcttattttt agaattttct atttgttggt gggcgaaaca atatattttt tgtaaatctt
     4081 tcaaggaaat cgttttagga agctttttct cttccttgta gtggagtcga agctgatgga
     4141 agggattttt tgaaattagt ttttcttctt ccagaaattt atagtatgat ttaagactag
     4201 caatcttacg ttttaatgtg ctagtctttt ttatatgttg gttgagaaaa gtaagatagg
     4261 acctaatatc attggtccta aagctataat actaatgtaa attggatttg tatgcttgga
     4321 tagtatgaga actaagtcgt cttt
//
LOCUS       DBNFCO010000111         4311 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.111, whole genome shotgun sequence.
ACCESSION   DBNFCO010000111 DBNFCO010000000
VERSION     DBNFCO010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4311
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.111"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            65..994
                     /locus_tag="AC1PIV_001822"
     CDS             65..994
                     /locus_tag="AC1PIV_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012997850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HIP6612802.1"
                     /translation="MEKIIITATAESIEQVKELLVAGVDRIYVGEADHALRIPTNFTY
                     DELREIAELVHSAGKELTVAANALMHQDMMDNIKPFMELMREIKVDYLVVGDTGIFYI
                     NKRDGYNFKLIYDTSVFVTSSRQINFWKDHGAVEAVLAREIPSEELFDIAKNLEMPAE
                     ILVYGASVIHHSKRTLLQNYYNFTKADETDLSRGRGLFLAEPSDPDSHYSIFEDKHGT
                     HIFINNDIDMMTKLSELDEHGYHNWKLDGIYCPGQNFVEIVKLFVQARDLIEKGDFTY
                     DQAFLLDEQVRKLHPAERGLDTGFYEFDRNKVK"
     gene            1292..2578
                     /locus_tag="AC1PIV_001823"
     CDS             1292..2578
                     /locus_tag="AC1PIV_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HIP6612803.1"
                     /translation="MSKTLKRPEVLSPAGTLEKLKVAIDYGADAVFVGGQAYGLRSRA
                     GNFTMDEMREGIEYAHARGAKVYVAANMVTHEGNEEGAGAWFRELRDMGLDAVIVSDP
                     ALIVICATEAPGLEIHLSTQASSTNYETFEFWKELGLTRVVLAREVTMEEVAEIRKRT
                     DVEIEAFVHGAMCISYSGRCVLSNHMSKRDANRGGCSQSCRWKYNLYDLPFGEERRSI
                     KGEIPEEFSMSAVDMCMIDHIPDMIENGVDSLKIEGRMKSVHYVSTVTNCYKAAVDAY
                     LESPERFEAIKQDLIDEMWKVAQRELATGFYYSPPSENEQLFGARRKIPEYKFIAEVV
                     AFDKETMTATIRQRNVINEGDQVEFYGPGFRHFETTIQDLHDSNGEKIDRANKPMELL
                     TIKLDREIYPGDMIRACKSGLINLYQEDGQSLTIRA"
     gene            complement(2994..3317)
                     /locus_tag="AC1PIV_001824"
     CDS             complement(2994..3317)
                     /locus_tag="AC1PIV_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612804.1"
                     /translation="MKRFLEVIFEQFTIFLEHGKAPKSIEPDSKEEIKNNLELALYKK
                     AAVHVIYGDRSFTGDIVKYDTDRQRIIMKNFKRQVTSIIKIEDIKKVTLVPDSIKTSQ
                     QQTKG"
     gene            3409..3624
                     /locus_tag="AC1PIV_001825"
     CDS             3409..3624
                     /locus_tag="AC1PIV_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018167072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HIP6612805.1"
                     /translation="MAEFTFEIEEKLLVLSENDKGWTKELNRVSFNGAPAKYDIRTWS
                     PDHTKMGKGITLSNEEFQVLLDAFANK"
     gene            complement(3636..4175)
                     /locus_tag="AC1PIV_001826"
     CDS             complement(3636..4175)
                     /locus_tag="AC1PIV_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HIP6612806.1"
                     /translation="MKTTSIKSLVYIAIGTALISTLSQISLSIGPVPFTLQTLAIGLV
                     ACLYKPKEAITSVSLYLVLGAIGLPVFAGFSGGFAALTGPTSGFLWGFLLYTIITSAL
                     TKSDSSPVTIFLACLLGTSICFLLGCCVFKLVSGASWTDTIGWTVLPFILPDLAKITL
                     VMICHRLLQPVIKKEAYFA"
BASE COUNT         1322 a          842 c          938 g         1209 t
ORIGIN      
        1 gtctgaatat taaaacacgg ctagtcactt atcagatatt tctctttttg atataattat
       61 ccttatggaa aaaattatca ttacagcaac agctgaaagt attgagcagg tcaaagaact
      121 gcttgtagca ggcgttgacc gcatttatgt aggtgaagct gaccatgctc ttcgcatccc
      181 aacaaatttt acctatgatg aactcaggga aatagcagag ctagttcata gcgctgggaa
      241 ggaattgacg gtcgctgcca atgccctcat gcatcaagat atgatggaca atatcaaacc
      301 gtttatggag ctaatgaggg aaatcaaggt tgattatctg gttgtcggag atactggaat
      361 tttctatatc aataaacgtg atggctacaa tttcaagcta atctatgata catctgtctt
      421 tgtgacttcc agtcgtcaga ttaacttttg gaaagatcat ggagcagtag aggctgtttt
      481 ggcaagagag attccatcag aagaactctt tgatattgct aagaacttgg aaatgccagc
      541 ggaaatcttg gtctacggcg cctctgttat tcaccattct aaacgaacct tgttacagaa
      601 ttactacaat tttacaaaag ctgatgagac agatttgtca cgtggacgcg gacttttctt
      661 agctgagccg agtgacccag atagccacta ttccattttt gaagataagc atggcaccca
      721 tatctttatc aacaatgaca ttgatatgat gaccaagctg tcagaattag atgaacatgg
      781 ttatcataat tggaaacttg atggtatcta ttgccctggt cagaactttg tggaaattgt
      841 taagcttttt gttcaagcaa gagatttgat tgaaaaaggc gacttcactt atgatcaggc
      901 cttccttttg gatgaacagg tacgtaagct ccatccagct gaacgtggct tggatacagg
      961 cttctacgaa tttgaccgca ataaggttaa ataataatat ttatagcaga atttatttac
     1021 tttaacctga cagagttagc tctgtcactt acaatgtaag gtcagagcac gaaaacgcct
     1081 ttgggcgatt ttctaatctc tgccctaggt ttccgagtga aacaacatcg tttacagtat
     1141 tctatcctgg cagagttagc tctgtcactt acaatgtaag gtcagagcac gaaaacgcct
     1201 ttgagcgatt ttctaaactc tgcactaggt ttccacatgg aaaagtatcg tttcatgtgg
     1261 aaaccgtcgc aaatagagga gattttacat gatgtcaaaa acattaaagc gtcccgaggt
     1321 cttgtcacct gctgggactt tggagaaatt gaaggttgcc attgattatg gtgctgatgc
     1381 ggtctttgtt ggcggccagg cctacggtct gcgtagccga gctggtaact ttaccatgga
     1441 cgagatgcgg gaagggattg aatatgccca tgcccgtggt gccaaggtct atgtagctgc
     1501 caacatggtc acccacgaag gtaatgaaga aggagcagga gcctggttcc gcgaattgcg
     1561 tgacatgggc ttggatgccg ttatcgtatc tgacccggct ctcatcgtta tctgtgcaac
     1621 cgaagcgcca ggccttgaaa tccacctgtc aacccaggct tcttccacca actacgaaac
     1681 ctttgagttt tggaaggaat tgggcttgac tcgtgtcgtc ctggcccgcg aagtgactat
     1741 ggaagaggtg gctgaaatcc gtaaacggac agacgttgaa atcgaagcct ttgtccacgg
     1801 tgccatgtgt atctcctact caggtcgttg cgttctctcc aaccacatga gcaaacgcga
     1861 tgccaaccgc ggcggttgct cccaatcttg ccgttggaag tacaacctct acgacctacc
     1921 tttcggcgaa gaacgccgtt cgattaaggg ggaaatacca gaggagttct ctatgtctgc
     1981 agtggacatg tgtatgatcg accatattcc agatatgatt gaaaacgggg tcgatagcct
     2041 gaaaatcgaa ggccgtatga aatctgttca ctacgtatca acagtgacca actgctacaa
     2101 ggctgcggta gatgcctatc ttgaaagccc agaaaggttt gaagcgatca agcaagacct
     2161 gattgatgag atgtggaagg ttgcccaacg tgaattggca acaggattct actatagccc
     2221 gccgagtgaa aatgagcaac tctttggagc ccgccgcaaa attccagaat acaaattcat
     2281 cgccgaagta gtggcttttg acaaggaaac catgactgca accattcgtc agcgtaatgt
     2341 tatcaatgaa ggtgaccaag tagaatttta cggaccaggt ttccgtcatt ttgaaacgac
     2401 tattcaggac ttgcatgatt caaatggaga aaagattgac cgcgccaaca agccgatgga
     2461 actcttaact attaagctgg accgtgaaat ctatcctggt gacatgattc gtgcctgcaa
     2521 atcaggcctc atcaacctct accaagaaga tgggcaatct ctaactattc gtgcataaac
     2581 atatagacat ttagtttttc ttttattact tcgacgtaag aggaaactcc gtttccttat
     2641 ttccaacttc aaacactcca ctggattgtt tgaactcgct ttgccgtact ctgcaggggt
     2701 gacttgctcc gcaagtgcta tctccaacct ccaaaggttc cccaaacctt tggagcgagt
     2761 actaaaagta aactaaaaga ctataaaaag gctgaaattt cagcctcaga acgtagataa
     2821 actcttaaaa atataaaaaa atgaagaagt ttgcgaaaga tagcaagtca ttaaactctt
     2881 agaaacattg atatttcggc gtttctgaga gtttttaatt ttcaacataa agaaaaaaga
     2941 ttgaagaaaa ttgtccaaaa tggacttttt cttcaatctg caaggctgaa atttcagcct
     3001 tttgtttgtt gttgagaagt cttgatgcta tctggaacca aggtgacttt tttgatgtcc
     3061 tcgattttta taatgctggt aacctgacgt ttgaaatttt tcatgataat ccgttggcga
     3121 tcggtatcat atttcacaat gtcacctgtg aaactacgat caccatagat gacatggact
     3181 gcagcttttt tatataaagc cagctccaag ttattcttga tttcttcctt gctatctggc
     3241 tcaatagact taggagcttt gccatgttct aaaaagatgg tgaactgctc gaaaataact
     3301 tctaaaaacc tcttcatggc gtaatccttt caaacttgat ataattatat tatctaattt
     3361 ttataaaaat gacaagcttt ttcgaataga taagtgagga ggtaacaaat ggcagaattt
     3421 acatttgaaa ttgaagaaaa attattggtc ttatctgaaa atgataaagg atggaccaag
     3481 gagcttaatc gagtatcttt taatggcgca ccagccaagt atgacatccg tacctggagt
     3541 cctgaccata ccaagatggg gaaagggatc actcttagta atgaggaatt tcaagttcta
     3601 ctcgacgcgt ttgctaataa ataaatgaag gaagcctaag caaaataggc ttcttttttg
     3661 ataacaggtt gcaataaacg atgacaaatc atgactagtg taattttagc taaatcagga
     3721 agaatgaaag gcagaacagt ccagccgata gtgtcagtcc aactggcacc tgaaactagt
     3781 ttaaatacac aacagccgag aaggaaacag atacttgttc caagtaggca ggctagaaaa
     3841 attgtaactg gtgaggagtc tgatttagtg agggcagaag tgatgatagt gtagagtaga
     3901 aacccccata gaaagccaga tgtcggtcct gtgagtgcag caaagccacc agaaaaacca
     3961 gcaaaaacag gtaaaccgat agcgccaaga actagatata agctgacact tgtaattgcc
     4021 tccttgggtt tgtatagaca agctactaag ccgatagcta aggtttgtaa tgtaaatggt
     4081 acaggtccga tagacagact gatttgtgaa agggtggaaa ttaaggctgt tccaatagcg
     4141 atataaacaa gtgatttgat agaagttgtt ttcatttgtt atcctcttaa aattttatgg
     4201 ttaacaaaaa ttatagtgag attggataag aaagtcaatg ctctttcatc ggctgtaaca
     4261 actctatagg tgatttttat aacagctaat aagaaactta tatagttaaa a
//
LOCUS       DBNFCO010000112         4244 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.112, whole genome shotgun sequence.
ACCESSION   DBNFCO010000112 DBNFCO010000000
VERSION     DBNFCO010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4244)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4244)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4244
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.112"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            62..1246
                     /locus_tag="AC1PIV_001827"
     CDS             62..1246
                     /locus_tag="AC1PIV_001827"
                     /EC_number="2.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003985 - acetyl-CoA C-acetyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HIP6612807.1"
                     /translation="MKKVAIVSAYRSAIGSFGGSLKDIEIADLGAQVLETALASKNIP
                     ADSVDEVIFGNVLSAGQGQNIARQIAIRAGIPQTASAYAVNKVCGSGLKSVLLAAQSI
                     MLGDNDVVVAGGIEIMSQAPYLSKTSRFGSKFGHITLEDSMLTDGLTDAFNDYHMGIT
                     AENVAEHYQVSRAEQDAFTYSSQEKAAKAIAEGRFVDEIVPIRLKNRKGETIFATDEY
                     PRLTPIEKLATLRPSFKKDGTVTAANASGINDGCAVLILMSDEKASELNIQPLTYIEA
                     YATSGLDPALMGLGPITASQKALQKLNKTVEDIDLFELNEAFAAQSIPVVKQLGIDPA
                     KVNVNGGAIALGHPIGASGSRILVTLIHELIKQEKELGLCSLCIGGGQGISLIVSNAQ
                     TS"
     gene            1275..2429
                     /locus_tag="AC1PIV_001828"
     CDS             1275..2429
                     /locus_tag="AC1PIV_001828"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HIP6612808.1"
                     /translation="MNIGIDKIGFAAPDYVLDLADLAQARNVDPNKFKIGLLQSEMAV
                     APVTQDIISLGAKAAEAILTEEDKQTIDMVIVGTESSVDQSKAAAVTIHGLLGIQPFA
                     RSIEMKEACYGATAGLSLAKSHIAQFPESKVLVIASDIAKYGVASGGEPTQGAGAVAM
                     LVTANPRILVLNNDNVCQTRDIYDFWRPNYDKYPRVDGKFSTEQYTDCLTTTFDYYQQ
                     KTGKTLNDFAAMCLHIPFSKQGLKGLQAIAQDEETLSRLTERFQEAIVYNKVVGNIYT
                     GSIFLSLLSLLENSRALETGDQILFYSYGSGAVCEIFSGQLVEGYRNHLQENRLEQLN
                     QRTKLSVKEYEQVFFEEITLDETGSSLDLPEDQSPFALIKVDNHKRIYRK"
     gene            2491..3771
                     /locus_tag="AC1PIV_001829"
     CDS             2491..3771
                     /locus_tag="AC1PIV_001829"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HIP6612809.1"
                     /translation="MSTFSGFYKKSRQERIDILRQNRSLAEDSLDILYKDENLPEAIA
                     GKMAENHLGTFSLPFSVLPELLVDGQTYSVPMVTEEPSVVAAASFGAKIIAKSGGFTT
                     TIHNRIMIGQVALYDISDHSRATQAILDHKESILENANQAHPSIVKRGGGARELTVES
                     KDEFLIVYLQVDVQEAMGANILNNMLEAVKDDLEELSKGQALMGILSNYATESLITAQ
                     CHIAISSLATSSAIAQETAQKIALASKLAQVDPYRAATHNKGIFNGIDAVVIAAGNDW
                     RAVEAGAHAYASRDGQYKGLSTWSIDGEHLVGSITLPLPIASVGGSIGLNPKVAVAFD
                     LLQQPKARQLASIIASVGLCQNFAALRALVTSGIQAGHMKLHAKSLALLAGAEEHEVD
                     QLAQLLRKEKHSNLETAQNLLAKMREHWEWERHP"
     gene            3999..>4244
                     /locus_tag="AC1PIV_001830"
     CDS             3999..>4244
                     /locus_tag="AC1PIV_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014917171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HIP6612810.1"
                     /translation="MEVLYQSCAGIDVHQANIVVCILHGPLTSTRPKREMATFDTTTK
                     GLRACHDFLSQFHVEAVGMESTGVYWRPVWHALCDDFE"
BASE COUNT         1232 a          984 c          926 g         1102 t
ORIGIN      
        1 taatggtata atagtaaggc tgaacacgac agttcaaaac gataccacta taggagttat
       61 catgaaaaaa gtagctatcg tgtctgccta tcgttctgcc atcggcagtt tcggaggtag
      121 tctgaaagat attgaaatcg ctgatttagg ggcgcaagtc ctcgaaacag ccttagctag
      181 taaaaacatc cctgcagaca gcgttgatga agttatcttc ggaaatgttc tttcagcagg
      241 acaaggacaa aatattgcac gtcaaattgc tattcgtgca ggcattcctc agacagcctc
      301 tgcctatgca gtcaataaag tctgtggttc cggtctcaaa tcagtcctcc tggctgccca
      361 gtcaatcatg ctaggtgaca atgatgtagt tgtggctgga ggcattgaaa ttatgagcca
      421 ggcaccttat ctatccaaaa ctagcaggtt tggtagtaaa tttggtcata ttactctaga
      481 agattctatg ctgacagacg gtctaacaga tgccttcaac gactatcaca tgggcattac
      541 tgcagaaaat gttgctgaac actatcaagt cagtcgcgca gagcaagatg cttttacata
      601 cagtagccaa gagaaggctg cgaaagctat tgctgaggga agatttgttg acgaaattgt
      661 tcctattaga ttaaaaaatc ggaaaggcga aactattttt gccacagatg agtaccctcg
      721 tctgacgcca attgaaaaat tggcaacact tcggccatct tttaaaaagg atggaaccgt
      781 caccgcagcc aatgcttctg gcatcaacga cggctgtgct gtcttgatac tcatgtctga
      841 tgaaaaagcc agtgagctaa atatccagcc actcacctat attgaggcct atgcaacaag
      901 cggtttagat cccgcattga tggggcttgg acctattact gctagccaaa aagcgctaca
      961 aaaactgaat aaaacagtcg aggatatcga tctattcgaa ctcaacgagg catttgcagc
     1021 ccaatcaatt ccagttgtca aacaactcgg cattgatcct gcaaaagtca atgtcaatgg
     1081 tggtgctatc gcccttggac atccaatcgg agctagtggt agtcgaatcc tagtcactct
     1141 gattcacgaa ttaatcaagc aagaaaaaga gcttggtctt tgctcacttt gtatcggagg
     1201 cggtcaaggc atctccctaa tcgtttccaa tgcgcaaaca agttaaccta tcatttgtac
     1261 acaaaggata tattatgaac atcggtattg ataaaatcgg atttgcggca cccgattatg
     1321 ttttagattt ggctgattta gcccaagccc gcaatgtgga cccaaataaa tttaagattg
     1381 gtcttcttca gtctgaaatg gctgtagctc ctgtcactca agatattatc agtcttgggg
     1441 caaaggctgc cgaagccatt ctgacagaag aagataaaca aaccattgac atggttattg
     1501 tcggcacaga atctagcgta gatcaaagta aggctgccgc cgtcaccatt catggattac
     1561 tcggtattca gcccttcgct cgctccatcg agatgaagga ggcttgttac ggtgcaacgg
     1621 ctggactaag tcttgccaaa agccatatcg ctcaattccc agaatcaaaa gtcctagtca
     1681 ttgctagtga tattgcaaag tatggagtcg cttctggcgg tgaacctacc caaggtgctg
     1741 gggcagttgc catgttggta accgcaaacc cacgaatttt ggtcctcaac aatgataatg
     1801 tctgccagac acgtgacatc tacgacttct ggcgtcccaa ctacgacaaa tatccacgtg
     1861 ttgatggtaa attttcaact gaacagtaca ccgattgctt gacgacaact ttcgactact
     1921 atcaacaaaa aacaggcaaa accctcaacg attttgctgc catgtgctta catattcctt
     1981 tctccaagca agggcttaaa ggactgcaag ctattgctca ggatgaagaa actcttagtc
     2041 gcttgacaga acgtttccag gaagctatcg tctataataa agtcgtcggc aacatctaca
     2101 ctggctctat cttcctctct cttctttccc ttttggaaaa tagcagagcg ttagagacag
     2161 gggatcaaat cctcttttat agctatggta gcggcgctgt ctgtgaaatt ttcagcggtc
     2221 aactcgttga aggttatcgc aaccacttac aagaaaatcg tttagaacaa ctcaatcagc
     2281 gtacaaaact cagcgttaag gaatacgaac aagtcttctt tgaagaaatt acccttgatg
     2341 aaaccggttc atcccttgac ctaccagaag accaaagtcc ctttgccctt atcaaagtgg
     2401 ataatcacaa acgtatctat cgtaaataaa agccaaaacg gcgccctttg gctctcacca
     2461 aggggcgctt tcctatagaa agaggaacct atgtcaactt tttccggatt ttataaaaaa
     2521 tcacgccaag agcgcattga tattctccgt cagaatcgtt ccctagccga agatagctta
     2581 gacattctat acaaagacga aaacctgcca gaagcaattg cgggaaagat ggcagaaaat
     2641 catctaggaa cgttttcctt acctttttct gtacttccag aacttctagt ggatggacaa
     2701 acttactctg taccgatggt tactgaagaa ccttctgtgg ttgcagctgc atctttcgga
     2761 gccaaaatca tcgctaaatc tggcggtttt acaacgacta ttcacaaccg tatcatgatt
     2821 ggacaagttg ctctctacga tatttcggac catagcagag cgacacaggc gattcttgac
     2881 cataaggaga gtattttaga aaatgccaat caagcacacc cttccattgt caaacgaggg
     2941 ggcggtgcaa gagaattgac tgttgagagt aaggatgagt ttttgattgt ctatcttcag
     3001 gttgatgtac aagaagccat gggagccaat atcctcaata acatgttaga agctgttaag
     3061 gatgacttag aagagctcag caagggacag gctttgatgg gaatcctctc caactatgca
     3121 acggagtcac tgatcaccgc ccaatgccat attgccatct ctagtctggc taccagctct
     3181 gccattgctc aagaaactgc tcaaaaaata gccctggcaa gcaaactggc gcaagtggac
     3241 ccttatcgtg ctgcgacaca taacaaaggg atttttaatg gtatagatgc tgtcgttatc
     3301 gctgcaggaa atgactggcg ggcagtcgaa gccggagccc atgcttatgc cagccgtgat
     3361 ggacaataca aggggctttc tacttggtct attgatggcg agcacttggt cggctccatc
     3421 accctacctc ttccgatcgc ctccgtcggc ggctcgatcg ggctcaatcc aaaggtagca
     3481 gtcgcttttg accttctcca acaaccaaag gcacgccaat tagcttctat catcgcttct
     3541 gtcggtctct gtcagaactt tgctgccctg cgtgctcttg ttacttcagg gattcaggct
     3601 ggtcacatga agctccacgc aaaatcccta gcgctacttg ctggcgccga ggagcatgaa
     3661 gtagaccaac tagcccaact cctgcggaaa gaaaagcaca gcaacctaga aactgctcaa
     3721 aacttattag caaaaatgag agaacattgg gagtgggaaa gacatccatg atggctccgc
     3781 cctcacccac agaataatga aaacgaacat aaagccctca ctaggtgtat aatcttagtg
     3841 agggctttgt ggttgacgag ttactgatgt tagtcatcgc gggaaaaact aacccactct
     3901 actgacgagc accccaaaat atgcgatagg catgagtata aaaatacgac tacaattcgg
     3961 tagataagct ctctaatttt tagaaggagg gaattatcat ggaggttctc tatcaatctt
     4021 gtgcaggtat tgatgtccat caagccaata ttgtcgtctg tatcctacat ggaccactca
     4081 cctcaactcg tccaaagcgt gagatggcta catttgatac aacgactaaa ggcctacgtg
     4141 cttgccacga ttttctcagt caatttcatg tggaagctgt tggtatggaa agcaccggtg
     4201 tctattggcg acctgtctgg catgctctat gtgatgactt cgag
//
LOCUS       DBNFCO010000113         3751 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.114, whole genome shotgun sequence.
ACCESSION   DBNFCO010000113 DBNFCO010000000
VERSION     DBNFCO010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3751)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3751)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3751
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.114"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            <1..261
                     /locus_tag="AC1PIV_001831"
     CDS             <1..261
                     /locus_tag="AC1PIV_001831"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HIP6612811.1"
                     /translation="ACGNGMGSSMVIKMKVENALRQLGVTDFQSASCSVGEAKGLAAG
                     YDIVVASNHLISELEGRTKGHLVGLDNLMDDNEIKTKLQAVL"
     gene            324..809
                     /locus_tag="AC1PIV_001832"
     CDS             324..809
                     /locus_tag="AC1PIV_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HIP6612812.1"
                     /translation="MNLQKSFTENNSIRLGLTAETWQEAVHKAVEPLIESGAATEEYY
                     DAIIASTEEYGPYYVLMPGMAMPHAQAGVGVLKDSFALITLTKPVVFSDGKEVSVLLT
                     LAATDPKIHTSVAIPQIIALFELENSIERLIACQTPEEVLAMVEESKNSPYLEGLDLE
                     S"
     gene            820..1482
                     /locus_tag="AC1PIV_001833"
     CDS             820..1482
                     /locus_tag="AC1PIV_001833"
                     /EC_number="4.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HIP6612813.1"
                     /translation="MKHIPNLQVALDHSDLQGAIKAAVSVGHEVDVIEAGTVCLLQVG
                     SELVEVLRSLFQDKIIVADTKCADAGGTVAKNNAVRGADWMTCICSATIPTMAAALKA
                     IKEVRGDKGEIQIELYGDWTYEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNKV
                     KKLVDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAAAAREFKDEIRRI
                     WG"
     gene            1488..2351
                     /locus_tag="AC1PIV_001834"
     CDS             1488..2351
                     /locus_tag="AC1PIV_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HIP6612814.1"
                     /translation="MARPIGIYEKATPKHFTWKERLEFAKELGFDFVEMSVDESDARL
                     ARLEWTKEERLDLVKAIYETGVRIPTICFSGHRRYPLGSNDPALEAKSLETMKQCIEL
                     AQDLGVRVIQLAGYDVYYEEKSPETRERFIKNLRQACDWAEQAQVMLGIEIMDDPFIN
                     SIEKYLAVEKEIDSPYLFVYPDTGNVSAWHNDIYSEFYLGHRSIAALHLKDTYAVTEN
                     SKGQFRDVPFGQGCVDWDNMFAVLKKTNYQGPFLIEMWSENCETVEETRAAIKEAQDF
                     LYPLIEKAGLN"
     gene            2351..3067
                     /locus_tag="AC1PIV_001835"
     CDS             2351..3067
                     /locus_tag="AC1PIV_001835"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001934215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HIP6612815.1"
                     /translation="MPKDLQEMRQRVYEANIALPAHGLVKFTWGNVSEVCRELGRIVI
                     KPSGVDYEKLSPENMVVTDLDGNVVEGDLNPSSDLATHVALYKAWPNVHAVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGPVPCARSLTAEEVNSAYEKETGSVIIEEFERRGI
                     DPVAVPGIVVRNHGPFTWGKNPAQAVYHSVVLEEVARMNRYTEQINPRVEPAPSYIMD
                     KHYLRKHGPNAYYGQKGDEH"
     gene            3152..>3751
                     /locus_tag="AC1PIV_001836"
     CDS             3152..>3751
                     /locus_tag="AC1PIV_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017772020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612816.1"
                     /translation="MRKFLQDSLTETAYYLELILSAILGLALLALSTLLFADLLSSLA
                     GDIQADTFIQNFLSRAMTLAVGVEFIKMLCKQSPSTVIEVLLVAIARQLIVEHGSSSD
                     YLIGIISVAILFAVRKYLFTQFDDSNNIIMRASQKVKVANIIARVKIPSEGSETLRDF
                     VTRKLNEEEKTIAIGACVYLKNVALRIDNMHGELITRVEI"
BASE COUNT         1049 a          801 c          910 g          991 t
ORIGIN      
        1 gcctgcggaa acggcatggg ctcatctatg gtcatcaaga tgaaggtaga aaacgccctt
       61 cgtcaactcg gcgtaacaga ttttcaatca gcttcttgct cagtcggtga agcaaaaggt
      121 ttagcggcag gatatgatat tgtcgtagcc tctaaccact tgatttctga gttggaaggt
      181 cgcacgaaag gtcacttggt tggtcttgac aacctcatgg acgacaacga aatcaaaaca
      241 aaattacaag cagtgctata aatagccgtt aggggtaggg agtttccctc cccctttcat
      301 atagcgtgta gaagggaaaa actatgaatt tacaaaaatc atttacagaa aataattcca
      361 ttcgcttggg attgacagcg gaaacctggc aggaggctgt tcacaaggct gttgaaccgc
      421 tgattgaaag tggtgctgca actgaggaat actacgacgc gatcatcgca tcaactgaag
      481 aatatggacc ttactatgtg ctcatgcctg gtatggctat gcctcacgcc caagcaggtg
      541 tcggcgtctt gaaggattcc tttgctttga ttaccttgac aaaaccagtc gtcttctcag
      601 atgggaaaga agtgtctgtt ctgctcactc ttgcagctac cgatccaaag attcatacat
      661 ccgtagctat tccacaaatt atcgccctct tcgaattgga aaattcgatt gagcgtttga
      721 ttgcttgtca aactcctgag gaagtcttgg caatggtgga agagtccaaa aacagtcctt
      781 acctagaagg tttagattta gaaagttagg agaaaaaaca tgaaacatat tccaaattta
      841 caagttgccc ttgaccattc agacttgcag ggagcgatta aagcagctgt ttccgttggt
      901 catgaagtgg atgttatcga ggcaggtacc gtttgtttgc ttcaagttgg tagcgaattg
      961 gtagaagtgc tacgtagcct cttccaagac aaaattatcg ttgcagatac caagtgtgcg
     1021 gatgcgggtg gtactgtggc taaaaacaat gctgttcgtg gtgcggactg gatgacttgt
     1081 atttgttcag caactattcc aactatggca gctgctttga aggctatcaa ggaagtgcgt
     1141 ggtgataagg gtgaaatcca aatcgaactc tatggtgact ggacttatga acaggctcaa
     1201 ctctggttgg acgcaggtat ttcccaagcg atttaccacc aatcgcgtga cgccctcctt
     1261 gctggcgaaa cttggggcga aaaagacctc aataaagtga aaaaattggt tgacatgggc
     1321 ttccgtgttt ctgtaactgg tggtttggac gttgataccc ttaaactctt cgagggtgta
     1381 gatgtcttca cctttatcgc aggtcgcggt atcacagaag cagccgaccc agcagcagcg
     1441 gcgcgtgaat ttaaagacga aatccgtcgt atctgggggt aagacctatg gcacgaccaa
     1501 tcggaatata tgaaaaggca acgcccaaac acttcacatg gaaggaacgt ttggagtttg
     1561 ccaaagaatt aggtttcgac tttgtggaaa tgtcggtaga tgagagcgat gcacgcttgg
     1621 ctcgtttgga atggaccaag gaagagcgtt tagacttggt caaggccatc tatgaaacag
     1681 gtgtccgcat tccgaccatt tgtttctcag gtcaccgtcg ctacccgctt ggctccaatg
     1741 accctgctct tgaagccaag tccttagaaa ccatgaaaca gtgtatcgaa ctggctcagg
     1801 atttgggcgt tcgtgtcatc cagttggctg gctacgacgt ttactacgag gaaaaatcac
     1861 ctgaaactag agagcgtttc atcaagaatc tccgtcaggc ttgcgactgg gcagaacagg
     1921 ctcaggtcat gttgggcatt gaaattatgg atgatccatt tatcaactca attgaaaaat
     1981 acctagccgt tgaaaaagaa atcgactcgc cttatctctt tgtctatcca gatactggaa
     2041 acgtgtctgc ttggcataat gacatttaca gcgaatttta cctgggacac cgttctatcg
     2101 cagcccttca cctcaaggat acctatgcgg taaccgaaaa ctccaagggt caattccgtg
     2161 atgtcccatt tggtcagggc tgtgtggact gggacaatat gtttgcagtc ttgaaaaaga
     2221 ccaactacca aggtccattc ttgattgaga tgtggtctga aaactgcgaa acggttgagg
     2281 aaacacgagc agctatcaag gaggcacaag atttcctcta tccattgatt gagaaagcgg
     2341 ggttaaacta atgccaaaag atttacagga aatgcgtcaa cgggtctatg aagccaatat
     2401 cgccctgcct gctcatgggc tcgtcaagtt tacctggggc aacgtatcag aagtctgccg
     2461 agaacttggt cgcatcgtca tcaagccctc tggtgtggac tatgaaaaat tgtcaccgga
     2521 aaacatggtg gtgaccgact tggacggaaa tgtagtggaa ggggacttga atccttcgtc
     2581 tgacttggcg acccacgttg ccctctacaa ggcttggcca aatgtccacg ctgttgtcca
     2641 tacccattcg acagaagcag ttggttgggc tcaggcaggt cgtgacattc cattttatgg
     2701 gacaactcat gcggactatt tctatggtcc ggtaccatgt gcccgttctt tgacagctga
     2761 ggaagtaaac tcggcctatg aaaaagaaac aggttcagtc atcatcgagg aatttgaacg
     2821 ccgtggtatc gacccagttg ctgtaccagg aattgttgtc cgtaaccatg gaccatttac
     2881 ctggggcaag aatcctgctc aggcagtcta ccacagcgtt gttcttgagg aagtagctcg
     2941 gatgaaccgc tacaccgagc agattaatcc aagggtggag ccagcaccaa gctatatcat
     3001 ggacaagcac tacctccgta aacatggtcc aaatgcctac tatggacaaa agggtgatga
     3061 acattaagtt cttgtgtgaa aaaaacagta gggaaaagta gcagactccc ccaaaaggag
     3121 aactgctttt tcccttttga tgaggagaaa gatgaggaaa tttttacagg atagtctgac
     3181 agaaacagcc tactatttag aattgatttt atctgccata cttggcttag cacttttagc
     3241 cttgtcaacg cttctttttg cagacctact cagctcatta gctggtgata ttcaagcgga
     3301 tacgtttatt caaaattttc tgagtcgtgc aatgaccttg gcggtcggag tcgaatttat
     3361 caaaatgctt tgcaaacagt cacctagcac cgtgattgag gtactcctgg ttgccattgc
     3421 tcgccaactg attgtagagc atggttctag tagtgattac ctgattggaa ttatttcggt
     3481 cgccatccta tttgcagtta gaaaatacct cttcactcag tttgatgatt ctaataatat
     3541 tattatgcgc gccagccaga aagtaaaagt ggctaatatc atcgcacgag taaaaattcc
     3601 aagtgaaggt agtgagactt tgagagattt tgtgacacga aaactcaatg aagaagagaa
     3661 aaccattgct attggtgcct gtgtatattt gaaaaatgtt gcccttcgga tagataacat
     3721 gcacggagaa ctgattaccc gagtagaaat t
//
LOCUS       DBNFCO010000114         3730 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.115, whole genome shotgun sequence.
ACCESSION   DBNFCO010000114 DBNFCO010000000
VERSION     DBNFCO010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3730)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3730)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3730
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.115"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            75..368
                     /locus_tag="AC1PIV_001837"
     CDS             75..368
                     /locus_tag="AC1PIV_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein"
                     /protein_id="HIP6612817.1"
                     /translation="MQKTLEKLKRSELFELLVEQAKEIESYQAKLVDLEKRIEYREAV
                     LGEIGSIAEASLAVTRIFEEAQLAANIYLEQVQKVTHKQSDNCEIGRTDEDGD"
     gene            358..960
                     /gene="lepB"
                     /locus_tag="AC1PIV_001838"
     CDS             358..960
                     /gene="lepB"
                     /locus_tag="AC1PIV_001838"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009909468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HIP6612818.1"
                     /translation="MATNKNKDYVTISDLPSISIMSEELDKIRYKERYLETLKNTIFT
                     LVTVVALAVLIAMLWLPVLHIYVSSMSPTLKAGDMVATVKTNTLSTGDMVAFYYNNKV
                     LVKRVVATSGQWVNIDEQGNVYANGKTLDEPYVKDKAYGQTDIKLPYQVPEGQYFVMG
                     DHRSVSIDSRNTAIGSIGEEQLVGKLTFRIWPFHKMGVIK"
     gene            979..1365
                     /locus_tag="AC1PIV_001839"
     CDS             979..1365
                     /locus_tag="AC1PIV_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612819.1"
                     /translation="MKILWERLFKFVQQYFREKKTAKITMVLSIIMAFGISYLLILPA
                     ITLETDSQESVLQSVYNQPTTVEQPVQEEQAESQLAQVQSAGSLFAEHENITVQVNYE
                     EHTFEQPVRLQVLPSEDSTKYIGLVR"
     gene            complement(1366..1755)
                     /locus_tag="AC1PIV_001840"
                     /pseudo
     CDS             complement(1366..1755)
                     /locus_tag="AC1PIV_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558050.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1723..2550
                     /locus_tag="AC1PIV_001841"
     CDS             1723..2550
                     /locus_tag="AC1PIV_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HIP6612820.1"
                     /translation="MASQIRHDLSLLVFFLITGLLLLLYPTVSDYWNSHYQSEAVATY
                     SEKLLDISKEEKQKILENVSAYNNTLEKGTIPNLNIDSVALKKYDSILNITDTGIMGY
                     VEIPKLQTTLPIYHGTDDAVLQVAVGHLAGTSLPIGGQGSHAAISGHRGLPSAKLFSD
                     LDQLVIGDTFMIQVLDNTLTYEIDKIITVTPDDVSPLMIDPNEDFVTLVTCTPYGVNS
                     HRLLVRGHRIENQLLARQVVSEGSIVKPILVSPFIALCLLGLLWSLFFIKKEVNLFM"
     gene            2680..2844
                     /locus_tag="AC1PIV_001842"
                     /pseudo
     CDS             2680..2844
                     /locus_tag="AC1PIV_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003104139.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
     gene            2933..3343
                     /gene="nmlR"
                     /locus_tag="AC1PIV_001843"
     CDS             2933..3343
                     /gene="nmlR"
                     /locus_tag="AC1PIV_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stress response transcriptional regulator NmlR"
                     /protein_id="HIP6612821.1"
                     /translation="MNIKEVSDVTGLSADTIRYYERVGLIPKIARKSSGVRDFVENDV
                     AVLEFVRCFRSAGMSIERLIEYMGLVQAGDSTVEARIDLLKEEREVLQSRLSKIQQAL
                     ERLDYKIENYQTILRGAENQLFTDGSGSCKKDRE"
     gene            complement(3369..3680)
                     /locus_tag="AC1PIV_001844"
     CDS             complement(3369..3680)
                     /locus_tag="AC1PIV_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HIP6612822.1"
                     /translation="MPLRHYQSHEYQYEEYIPKEKKANFQTYQAKNANKERLKELLFF
                     VNIAFFSLITVIASYVYLSVGIPVFIAIILASATGFLGLRLVQIGLKKKFKPKQVIRK
                     N"
BASE COUNT         1246 a          593 c          769 g         1122 t
ORIGIN      
        1 ttagaagtaa ataagcatat attttgtagt gaaagcaata taagcaaaaa ggagagagga
       61 agaagcaatg ttaaatgcaa aagaccttag aaaaactgaa gcgttctgaa ttatttgaac
      121 tcttggttga gcaggcaaag gaaatagagt cttatcaagc aaaattagta gatttggaaa
      181 aaagaattga gtatcgcgaa gcggttttgg gagaaattgg ttcgatagcg gaggcgtctc
      241 tagcagttac taggattttt gaagaagcac aattggctgc aaatatttat cttgaacaag
      301 ttcaaaaagt tacacataaa caatctgata attgtgaaat agggagaaca gatgaggatg
      361 gcgactaata aaaataagga ttatgttacc atatcagatt tacccagtat atcaataatg
      421 tcagaggagc tggataaaat acgatataaa gagcggtatt tagagacatt aaaaaatact
      481 attttcacgc ttgttactgt cgttgcactt gcagtattaa tagccatgtt atggttgcca
      541 gttctacata tttatgtaag ttccatgtct cctactctga aagcaggtga tatggtagca
      601 actgtgaaga caaatacact ttcaactgga gatatggttg cattctacta caataataag
      661 gttttggtaa aaagagtagt agcaacttct ggtcagtggg taaatataga tgagcagggg
      721 aatgtttatg caaatggaaa aacattagac gaaccctatg ttaaagataa ggcctatggt
      781 caaactgata ttaaactacc gtaccaggtt ccagaaggtc aatattttgt aatgggagat
      841 catcgcagtg tatctattga ttctagaaat acagctattg ggtcgattgg tgaggagcaa
      901 ctggttggaa agttaacctt tcggatatgg ccatttcata aaatgggagt aatcaaataa
      961 aggaaggaga tataaaacat gaaaatatta tgggaaagat tgtttaaatt tgttcagcaa
     1021 tactttcgag agaaaaagac tgcaaaaata actatggtgt tgtcaataat tatggctttt
     1081 ggaatatcat atttgctgat tttaccagcc attactttag agacagacag tcaggagagt
     1141 gttctgcaat cagtctataa tcagccaaca acagtagaac agccagttca agaagaacag
     1201 gcggagtcac aattggcaca ggttcaatct gctggaagct tattcgctga acatgaaaat
     1261 ataactgtac aagttaacta tgaggagcat acatttgaac agccagttcg gttacaggtt
     1321 ttaccctcag aagatagtac aaaatatatt ggacttgttc ggtaactaca tcatctcatg
     1381 gttgatgata ccacaaatca actcagttct taattcaaac cgttttctac gattacgata
     1441 gggctgtgcc atgattttaa aggttttaaa tttggcatta aagtgttcaa cttcaatacg
     1501 gattttagct atctctcgat tcaaccgtct atcctcttcg gttaagaggt gatgtttaga
     1561 atgcttagca ggaataaagg tattttcgtg aaatttcaag atgcctaaat accctaaatc
     1621 tacgaaagca agggtatttt ggggcaaact atagccaata ctctccttaa aaagggtaaa
     1681 atcatgcgta tgaccatctg aaaaagccaa ttgacaagca cgatggctag tcaaatcagg
     1741 catgatttga gtctgctagt ctttttctta ataactggcc tattattgtt attatatcca
     1801 acagtaagtg attattggaa ctcacattat caatcagaag cagtagctac ttattctgag
     1861 aaattattgg atatttcaaa agaagaaaaa caaaaaattt tagaaaatgt cagtgcatat
     1921 aacaacacgc tcgaaaaggg gacaatacct aatttaaata tagacagtgt agctttaaaa
     1981 aagtatgact caattttaaa tatcacagat actggtatta tgggctatgt agaaattcct
     2041 aagttgcaga caacgttacc tatttatcac ggaacggatg atgccgtatt gcaggtagca
     2101 gtaggtcacc ttgctgggac ttcccttccc attggcggtc agggaagtca cgctgctatt
     2161 tcaggacatc ggggattgcc ttctgcaaaa ctgttttctg atttagatca gctggttata
     2221 ggggacacat ttatgataca agttttagat aacactctga catacgaaat tgataaaatt
     2281 attacggtta ctccagatga tgtatctcct ttgatgatag atccgaatga ggatttcgta
     2341 acccttgtga cttgcacacc ttatggtgtt aatagccacc gattattagt tagaggtcat
     2401 cgaattgaaa atcaactact tgctaggcaa gtagtctcag aaggatcaat tgtaaaacct
     2461 atactggttt ctccttttat tgctttatgt ttattaggac tactttggag tttatttttt
     2521 ataaaaaaag aagtaaattt gtttatgtga cttagataat atcgcaaaga atgtcaaacc
     2581 attcgacttt gttctttagc ttttaagctt aggaaaggga ggtttttcaa ctcccaatca
     2641 tccaaaaggt gaaatagaag ataaaccaaa tgacgatatg tcaatgtcct ctatacgcca
     2701 gaaaaaggtg gcaagcgagc ggtcggctac ggcattgaaa ttcccaaaga atttgaaggc
     2761 aaattcaagt ttgcccgcca acgctccaaa ctagctgggg aaatccgtgg cactttcttc
     2821 gttgtcaagg gtaactattt ataggggaga aaatctgggg aaactcagat tttttgtcgc
     2881 atacttgact tcaaggtata taatagatat acaaaacgaa gggagaatga atatgaacat
     2941 taaagaagtt agtgatgtaa caggtctatc ggcagatacc attcgctact atgagcgggt
     3001 agggcttatt cccaaaattg caagaaaatc ttctggagta agggactttg tggaaaatga
     3061 tgtagccgtt ttggaatttg ttcgctgttt taggagtgct ggtatgtcta ttgagcgctt
     3121 gattgagtat atgggcttgg tgcaggctgg cgatagtact gtggaagccc ggattgattt
     3181 actaaaagag gaacgggaag tcctgcagtc acgcttgtcg aaaattcagc aagctctaga
     3241 acgtttagat tataagatag aaaattacca gactatatta agaggtgcag aaaatcaatt
     3301 gtttacagac ggcagtggtt catgcaaaaa agacagagaa taactttctc tgtcttcata
     3361 cttcattatt aattttttct gataacttgt ttgggtttaa atttcttctt tagtccaatt
     3421 tgaaccaaac gtagtccaag aaaacccgtc gcacttgcca atatgatggc aataaaaaca
     3481 ggaatgccta cagatagata gacataacta gcgatgactg ttatcaaact aaaaaatgcg
     3541 atattaacaa aaaacaacaa ttcctttaga cgttctttat tggcattttt tgcttgatag
     3601 gtttgaaaat tagccttttt ctctttcggg atatactctt cgtactggta ctcatgggac
     3661 tgatagtgtc ttaatggcat atcgtctcct tttctgctct ttaaagaata ccatatcatt
     3721 gatgaattat
//
LOCUS       DBNFCO010000115         3606 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.116, whole genome shotgun sequence.
ACCESSION   DBNFCO010000115 DBNFCO010000000
VERSION     DBNFCO010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3606)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3606)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3606
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.116"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            <1..618
                     /locus_tag="AC1PIV_001845"
     CDS             <1..618
                     /locus_tag="AC1PIV_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001213956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HIP6612823.1"
                     /translation="ENFAKHENKWRNNSEINDSNIPYLKTSIYSLIANSSLLDELKRV
                     LKEHVANERLFLEFNINSKETSQHLDILYKEVSVLSLGQKVVAMLDFLLAYSDYSKDF
                     RPLIIDQPEDNLDNRYIYRHLVQQFRDVKAQRQIILATHNATIVTNSMTDQVVIMESD
                     GAHAWIESQGYVSEKFIKNHIINQLEGGRDSFKHKMSIYETALSE"
     gene            956..1318
                     /locus_tag="AC1PIV_001846"
     CDS             956..1318
                     /locus_tag="AC1PIV_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013851909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1252 family conjugative relaxosome accessory
                     protein"
                     /protein_id="HIP6612824.1"
                     /translation="MTESYRTIRKEINLTLEEFEQIQLLMRKENAEQFSPFVRQKLLD
                     IVNNKDDIRDWFILWQSQKIEQISRDILQVATLAERGHQVTSEHLRIILTCVQELMTE
                     VEKAVPLSSEFRDKYMGG"
     gene            1321..1686
                     /locus_tag="AC1PIV_001847"
     CDS             1321..1686
                     /locus_tag="AC1PIV_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HIP6612825.1"
                     /translation="MENRYRTNLKKVFLTDQELANLNNHISQSSCQNFSAYARKVLLN
                     PNMTFLTIDTSNYQDLVFELRRIGNNINQIAKTVNQTKLLTVEQRDNLKTGIGQLIAE
                     VDKDFYVKCQKLREFYGSH"
     gene            1673..3556
                     /locus_tag="AC1PIV_001848"
     CDS             1673..3556
                     /locus_tag="AC1PIV_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1250 family conjugative relaxase"
                     /protein_id="HIP6612826.1"
                     /translation="MVVTKHFAVHGNKYRKSLIKYILNPAKTDQLKLVSDFGMSNYLD
                     FPNYEEIVEMYQANFVNNDRLYDSRNDRQQIKQNKIHAHHLIQSFSPEDNLTPEEINR
                     IGYETIKELTGGNFRFIVTTHTDRLHVHNHILINSVDLNSHKKLKWDYAQERNLRMIS
                     DRLSKEAGAKIITPNRYSHEKFVTYRKSNHKFELKQRLYFLMENSKDFDDFLSKAEAL
                     NVQIDFSRKYARFLMTDMPMKRVIRGKQLDKRQPYTEEYFREHFAKRAIEQCLDFLLP
                     RVRDLSQLLEFAREPNLAMSLKQKNVAFTLTKNSQSITVNNQKVSSKNLYDVQFFETY
                     FEKRGEVPDIDQSQLISDFEGYCEEQDKEKLAYEDLQEAYQAFKEKRDQVQEFDVVLA
                     DHQIDKLVKDGLFIRMNYGVKKDGLVFIPNRHLDIKETESGKHYHAFIRETAQFFIYN
                     KEASELNRYMRGRELIRQLTNDSQTISKRKRPTIDTLKKKIEEINLLIELGTENKSYQ
                     DIKDEIIKDIAQLDLTITEIQEHIDHLNKVAEVLLNLDNNDIENRRLAKYDYAKMNLT
                     AAIKLEQVEKEIEIYQIKLDKSIDDYEYLIRRLEKFVKILNEIDSSKDELKFEHSEKN
                     VKE"
BASE COUNT         1269 a          596 c          710 g         1031 t
ORIGIN      
        1 gagaattttg caaaacatga gaataagtgg agaaataatt ccgagataaa tgattctaac
       61 ataccctatt taaaaactag tatttattct ttaatcgcaa atagtagttt actagatgag
      121 ttaaagagag tgctaaaaga acacgtagcc aatgaaagac tttttttgga gtttaacatt
      181 aactcaaaag aaacatcaca acatcttgac attctttata aagaagttag tgtattaagt
      241 ttgggtcaaa aagttgtagc gatgttagat tttttactag catatagtga ttattcaaag
      301 gatttcagac cattaattat tgatcaacct gaagataatt tggataaccg ctatatatac
      361 agacatttag ttcaacagtt tagagacgtg aaagctcaac gacaaattat tttagcaacc
      421 cataatgcga caattgtaac aaattccatg accgatcaag tggtaattat ggaatcagat
      481 ggggctcatg cttggattga atcacaggga tatgttagtg aaaaatttat aaaaaaccat
      541 attatcaatc aattggaagg tggaagagac tcatttaaac ataagatgtc catatatgag
      601 acagctcttt ctgaataata taaggaaatg aaaagtaggt tagaaatatc ctactttttg
      661 ttttgtgata ccttttccaa atcacctcta ttatcctaat atcattccta aaaaaatcaa
      721 tccatgattt ttcactgggg gtttgggggc gaagccacca agttatctta tcgtcggcta
      781 tcaaaactca aaggttttgg tcggctggcg ataagatttt tgggatattg tggacacaat
      841 atctgagctc gcaaaagccg aaaagggaag atttgaggct tttagggagc ccccgtatca
      901 gatatggtat cggtgctaac ccgctagagg gaaatgtgag aaggagtgta tcatcatgac
      961 agaaagttat cggacaattc gtaaggaaat caacttgacg cttgaggaat ttgagcagat
     1021 tcaactactg atgagaaagg agaatgcgga gcagttttct ccctttgtta gacaaaaact
     1081 attggacatt gtcaataaca aggatgacat cagagattgg tttattctgt ggcaatctca
     1141 aaaaatagaa caaatcagta gagatatttt acaggtagca actctagcgg aacgaggcca
     1201 tcaggtcacg tcagaacact taagaattat attgacttgt gttcaagaac tgatgacaga
     1261 agtagagaag gcagtaccac tcagttcaga atttcgagat aagtatatgg gaggttagat
     1321 atggaaaatc gttatcgaac caatctcaaa aaagtctttt taacagacca ggaacttgcg
     1381 aacctgaaca atcatattag ccaaagttct tgtcaaaatt tttctgctta tgccagaaag
     1441 gttttgctta atccaaatat gaccttttta acaattgata ccagtaacta ccaagacttg
     1501 gtttttgaat tacgtcgaat tggcaataac attaaccaga tagctaaaac agtcaatcag
     1561 acaaaacttc tgacagtaga gcagcgagat aatttgaaaa cgggcatagg tcagctgatt
     1621 gcggaagttg ataaggactt ctatgtcaag tgtcaaaagt tgagggaatt ttatggtagt
     1681 cactaaacat tttgcggttc atggcaacaa ataccgtaaa agtcttatca agtatattct
     1741 aaatccagct aagactgacc aactcaaatt ggtttcagat tttggaatga gcaattacct
     1801 cgacttccct aattatgaag aaatagttga gatgtatcag gcaaactttg tcaataatga
     1861 taggctttat gattcgagaa atgaccggca acaaatcaag caaaataaaa ttcatgctca
     1921 tcatcttatc cagtcattct cacctgagga taatcttaca cctgaagaaa tcaatcgtat
     1981 tggttatgag acgataaagg agttgactgg cggaaacttt cgctttattg tgacaaccca
     2041 tacggatagg ttgcatgttc ataaccatat cctcatcaat tctgttgacc tcaattctca
     2101 taagaaactc aaatgggatt atgctcagga gagaaattta cggatgattt ctgaccgtct
     2161 ttccaaagaa gcaggtgcca aaattatcac accgaaccgt tattctcatg agaagtttgt
     2221 gacctatcgc aaaagtaatc acaaatttga attgaagcaa cgtctttatt ttctgatgga
     2281 gaatagtaag gattttgacg actttttatc caaggcagaa gcattgaatg ttcagattga
     2341 tttttcaaga aaatacgctc gttttttgat gacggatatg cccatgaagc gagttattcg
     2401 aggcaagcaa ctagataaac gtcaacccta taccgaggaa tactttcgag agcactttgc
     2461 caagcgagcg attgagcaat gtttagattt tctcttaccc agagttcgtg acctttcaca
     2521 acttttggag tttgcaagag aacccaacct tgctatgtct ctaaaacaaa agaatgtggc
     2581 gtttactcta acaaaaaata gtcagagcat tacagtcaat aatcaaaaag tcagttccaa
     2641 aaatctctac gatgttcaat ttttcgaaac ttactttgag aaacgtggag aagttcctga
     2701 tattgaccag tcgcaactta tttccgactt tgagggatat tgtgaggaac aagataagga
     2761 aaagctagct tatgaagact tgcaagaggc ttatcaggca tttaaggaga aaagagacca
     2821 ggttcaagag tttgatgtcg tcttagctga ccatcagatt gataagttag tcaaagatgg
     2881 tctctttatc agaatgaact acggcgttaa aaaagatggc ttggtcttta tcccaaaccg
     2941 tcatttagat attaaagaga cagagagtgg taaacactac catgccttta tccgtgagac
     3001 cgcacaattt ttcatttaca ataaggaggc gtccgaactc aatcgctata tgcgagggcg
     3061 tgaactcatt cgtcagttaa ccaatgatag ccagactatc tctaaaagaa aaagaccgac
     3121 cattgacaca cttaagaaaa agattgaaga gattaatctt cttattgagt tgggtacgga
     3181 gaataagtct tatcaagata ttaaagacga gattattaag gatattgctc aattagattt
     3241 gaccattaca gagattcagg aacacataga tcatctcaac aaggttgcgg aagtcttgct
     3301 taacctggac aataacgata tagagaaccg ccgcttggcc aaatatgact atgccaagat
     3361 gaatctaact gcggctataa aactggaaca agttgagaaa gaaatcgaaa tctatcaaat
     3421 taagttagat aagtcaatag atgattatga gtatttaata aggaggttgg aaaagtttgt
     3481 caaaatttta aatgaaatag actcaagcaa ggatgaacta aaatttgaac acagtgaaaa
     3541 aaatgtgaaa gaatagcatt tttcggattt attgatacca aatattgagt actctgaaga
     3601 aattct
//
LOCUS       DBNFCO010000116         3596 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.117, whole genome shotgun sequence.
ACCESSION   DBNFCO010000116 DBNFCO010000000
VERSION     DBNFCO010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3596)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3596)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3596
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.117"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            123..812
                     /locus_tag="AC1PIV_001849"
     CDS             123..812
                     /locus_tag="AC1PIV_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HIP6612827.1"
                     /translation="MNFSFLPEYWAYFNYGAIVTLIIAFFSVFFGSILGVLLAFAQRS
                     KYKVLAWTANIYVWIFRGTPMIVQIMIAFAMTHFVAPTFQLGILTVDLTRLIPGIIVI
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKQAMRYVIMPQAIKNILPALGNEF
                     VTIVKDSSLLSTIGVMELWNGAQTVQSTSYIPLTPLVFAASYYLIMTTVLTVIIQSFE
                     KKLNKGGQFHV"
     gene            805..1539
                     /locus_tag="AC1PIV_001850"
     CDS             805..1539
                     /locus_tag="AC1PIV_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019805208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015424 - ABC-type amino acid transporter
                     activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HIP6612828.1"
                     /translation="MSNAIISIKDLHKYFGKNEVLKGIDLDIQQGQVVVIIGPSGSGK
                     STFLRTMNLLEVPTKGTVTFEGVDITDKSNDIFKMREKMGMVFQQFNLFPNMTVLDNI
                     TLSPIKTKGIAKDEAEKKAKELLEKVGLPDKANAYPQSLSGGQQQRIAIARGLAMDPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMDGGVI
                     VEDGTPEEVFEHTKEERTKDFLSKVL"
     gene            1669..2517
                     /locus_tag="AC1PIV_001851"
     CDS             1669..2517
                     /locus_tag="AC1PIV_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009909467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HIP6612829.1"
                     /translation="MTVIDGKALGVKLQAALAEKTARLKEEKGLVPGLVVILVGENPA
                     SQVYVRNKERSALAAGFKSEVVRVPDTISESDLLDLIERYNQDDEWHGILVQLPLPAH
                     ISEEKVLLAIDPDKDVDGFHPTNMGKFWSGHPVMIPSTPAGIMEMFKEYQIELEGKSA
                     LVIGRSNIVGKPMAQLLLDADATVTIAHSRTKNLPDLARQADILVVAIGRGHFVTKEF
                     VKLGAVVIDVGMNRDENGKLIGDVKYDEVSEVASYITPVPGGVGPMTITMLMEQTYEA
                     CVRSAK"
BASE COUNT         1047 a          566 c          802 g         1181 t
ORIGIN      
        1 gaagtgagag gcacctaagg gtgctttttt cttgtgtaaa ttgaatatta taaacaaaag
       61 tattgcataa atattcaaaa atggtataat agactctaaa tgacagaatt ggagtaagat
      121 gaatgaattt ttcttttttg cctgagtatt gggcttattt taattatggg gcaattgtta
      181 ccctcattat tgcatttttc tcagtatttt ttggtagtat tttaggtgtg ttgcttgcct
      241 ttgctcagcg tagtaagtat aaagttttag cttggactgc caatatctat gtctggattt
      301 tccgtgggac accgatgatt gtccagatta tgattgcttt tgcgatgaca cattttgtag
      361 caccaacttt tcagctagga attttgacgg ttgatttgac gcgcttgatt ccaggtatca
      421 ttgttatttc gatgaactcg ggtgcctatg tatctgaaac tgttcgtgca ggtattaatg
      481 ctgtaccaaa aggacagctg gaagcagctt attcgcttgg tattagacca aagcaggcga
      541 tgcgttacgt tatcatgcca caggctatca agaatattct tccagccttg ggaaatgaat
      601 ttgtgactat tgttaaggat agttcacttt tgtcaaccat cggtgtgatg gaattatgga
      661 acggtgctca gacagttcaa tccacttctt atattccttt aacaccactt gtatttgcag
      721 cgagctatta tctaattatg acaacggtgc taacagtgat tattcagtcg tttgagaaaa
      781 agttgaacaa gggagggcag ttccatgtct aatgcgatta tttctatcaa ggatttacat
      841 aagtacttcg gaaagaatga ggttctaaaa ggaattgatt tagatattca acaaggtcag
      901 gtggtcgtta ttatcggtcc atcagggtca gggaaatcga ctttcttacg tacaatgaac
      961 ctcttagaag tgccaaccaa gggaactgtt acatttgaag gtgttgatat tactgacaag
     1021 tcaaatgata ttttcaagat gcgtgaaaag atgggaatgg tttttcaaca gttcaatctt
     1081 tttccgaata tgacggtatt agataacatt actttatcac ctattaagac aaagggaatt
     1141 gcaaaggatg aggctgagaa gaaggctaag gaattacttg aaaaggtagg attgccagat
     1201 aaggcaaatg cctatccaca aagtctttca ggtggtcagc aacaacggat cgctattgca
     1261 cgtggtctgg ccatggaccc agatgtccta ctttttgatg aaccgacctc tgcactagac
     1321 cctgaaatgg ttggtgaagt tcttgctgta atgcaggatt tggccaagtc agggatgacc
     1381 atggttatcg tgactcatga gatgggattt gcgcgtgagg tagctgacag ggttatcttt
     1441 atggatggcg gtgtcatcgt ggaggatgga acgcctgaag aagtctttga acataccaag
     1501 gaagaacgga ccaaggattt cttgtctaag gtcttgtaat aaatgaacaa ataagtacga
     1561 ctccgatatt gttcggagtt ttttgctata tgctatattc tactttgtac aagtatagtc
     1621 agtcggagaa ttttagggta taatagaaaa aacaaaagga gtgtaggtat gacagtcatt
     1681 gatgggaaag cactaggtgt aaaattgcag gctgctttgg cggagaaaac tgctcgatta
     1741 aaagaagaaa aggggttggt accaggtctt gtagttattt tagttggcga aaatcctgct
     1801 agtcaggttt atgtacggaa taaggagcgg tcagctctag ctgctggatt caagagtgag
     1861 gttgttcgcg ttccagatac gatttctgag tcagacttgt tggatttgat tgagcgctat
     1921 aatcaggatg atgaatggca tggtattttg gtgcaattgc ccttaccagc ccacatcagc
     1981 gaggagaagg tcttgttggc cattgaccca gataaggatg tggatggttt tcatccgact
     2041 aacatgggga aattctggtc aggtcatcct gttatgattc catctacccc agcaggaatt
     2101 atggaaatgt tcaaagaata tcagattgag ctggaaggga agtctgcttt agttattggt
     2161 cgttctaata ttgttggtaa accgatggca cagctgttat tggatgccga tgctactgta
     2221 acgattgcgc attctcgcac caaaaacttg ccagatcttg ctcgtcaggc cgatattctt
     2281 gttgttgcca ttggtcgtgg tcattttgtg accaaggaat ttgttaagct aggtgccgtg
     2341 gtgattgatg ttggtatgaa tcgtgatgaa aatggcaagc taatcggtga tgtcaaatac
     2401 gatgaggtat cagaagtggc aagttatatt accccggttc caggtggtgt tggtccgatg
     2461 actattacca tgttgatgga acagacctat gaagcttgtg tcagaagtgc aaaataagat
     2521 agagagttta ataaaaataa atatatccat gcctgctttg gtaaagccct gttcttagaa
     2581 cctgtattta caagcgaagt actcatatta agagacagat ttagctaatc aaggtaattt
     2641 ttttggggga tattgattgt attttgaaaa aaactaatga tgagtagctt aaaaactagc
     2701 cttagaatag aagcgttgaa ctgtgaatac aggttcttaa attatgcttg tagttttggt
     2761 agctaacagt aatgagtgca gtccccgtat gaataagtct atttttaaac gactctactt
     2821 attttattag tcatattcaa taaatcagtt ttaagacgga tgtgactttt agtaatattg
     2881 gttatactat acccaatcct aaatattttt cataatctcc tgaaaagcct gatcgtgtga
     2941 tcaggttttt ttgtatgcaa aaatggatct gtacaaaaaa acagtactat ttctcaaagt
     3001 ttgaacaaca tcccagtgta gtaaaaacgt ttggagacag attgtttcag ctcaacaact
     3061 gggaataaag atttattgcc gaactctttt atactcttcg aaaatcaaaa tcagacgttg
     3121 ttgacttgat ttgatgaact tcagttctat ctgcatctgc gtcgcctagt ctgattttca
     3181 ttgagtatta tctgtttagt tctttctctc tttcattttg tgtttataat gttttaggtg
     3241 attgtgggac gttttcagtg aaactgctaa tggaacggtt ttactcctag ccttatctga
     3301 gtaataatag gataaaactc atatacccac ataagagtga tagaggtttg tgaatagtat
     3361 ttagttagaa acatttgtta tcaaatacag gttctacgtt atatttaaag aacttctcta
     3421 tcattcgtta aatatttctt ctccgattta tcgctagata ggagcagtgt atgcgtttct
     3481 aaaaatctaa agttggagga tgttcaattt taaataagtt acaatctgca aatcactact
     3541 aaaatcaatt tatcccttat acagggtaat gtaataaatt gttttttctt tgtttt
//
LOCUS       DBNFCO010000117         3570 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.118, whole genome shotgun sequence.
ACCESSION   DBNFCO010000117 DBNFCO010000000
VERSION     DBNFCO010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3570
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.118"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            77..838
                     /locus_tag="AC1PIV_001852"
     CDS             77..838
                     /locus_tag="AC1PIV_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612830.1"
                     /translation="MTKKIIFILLFFVVCVYFYSFIPLVQTVPSVFQTPYRTLVQSEF
                     EAIYKYNGIEISERNFWNKPINGRKPQDTLNEKATILFKKYNLLEKEAKKHEYKKEAL
                     DFNKVDWKTVSNRYIELKQIVIDEKIKDINQDEIERYYLANTENFERQDFISGNISIW
                     NDGIIISTESVDITEETVRNITERYPDLELELKNIEVGHQVSWGQNGVYYTFTCLSRE
                     EKGIIPLSEITDAVAMQCAEELVDNWLNKEIDSLK"
     gene            1061..1819
                     /locus_tag="AC1PIV_001853"
     CDS             1061..1819
                     /locus_tag="AC1PIV_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIP6612831.1"
                     /translation="MKSNKEQKYFWLTFSLIVALMIWWFLSNYDRTSRSFPNIILVWN
                     ALLIMIDKGFIFEDIFSSLTSVFFGFTSGFLLSAPNALLMAWYSPYRNIVKPWIQFIR
                     NIPPLAYVPLVVISAGVGLLPQVIVIAIATFLTMTVTIYQGIINIDPNLIKAARILGA
                     SDFEIFKRILVPSSIPFIMTAVRLGTSISLTTIIAAESTGATSGMGMRIRSLNNSFDS
                     SGMLLYIILIGVIGLLLNKLVDLIERKLTGWQQK"
     gene            1804..2586
                     /locus_tag="AC1PIV_001854"
     CDS             1804..2586
                     /locus_tag="AC1PIV_001854"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIP6612832.1"
                     /translation="MATEVKKIKVKIEDVSKSFQTNHGEVVALNQINLEIFENEIVTV
                     VGPSGCGKSTLLNLVAGLEPVTSGKIYCDDNEIVGIGVERGVVFQQYALFPWMSVLQN
                     VMFGPEMQGKSKLEASEIANKYIKMVGLQEFSNHYPKELSGGMKQRVAIARAYAVNPS
                     ILLMDEPFGALDALTRIQLQEELIEMLGQEQKTCFFITHDIEEAVLLGNRVIVMSPRP
                     GEIKEIVNVDLPFPRNQLTKFEKNFMDIKNHIWSLVYKDFLI"
     gene            2625..>3570
                     /locus_tag="AC1PIV_001855"
     CDS             2625..>3570
                     /locus_tag="AC1PIV_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HIP6612833.1"
                     /translation="MAKYMKYKNFIWFICSIITLIFLSSCSSIQTSSSGHSAKVDTIR
                     IAYMPNFASLHDIITGINSGIFKEEGLEVELIEFADGPTIIASLESGSIDIGNIGPGA
                     HKLAIEGRAEVVAFSQLGNADELIARSDRGIDSIEDLRGKKIGTASGTSAETILKLAL
                     LEADLSEKDVEIIDMDASAIVTAMLSGSIDVAATWSPNTTFIKRELKEKVVVLADNSR
                     YREQSPAIASYVTFPGYSEKNNEKISKFLKGLYRAMDYRAEHMKEVSKWVATQIGSDI
                     TAVQDQLQDGEWLTSRQMIQLINTGILQQYYEKQQKNLI"
BASE COUNT         1229 a          473 c          685 g         1183 t
ORIGIN      
        1 tttatttagc ctcttcgtag tcctaatttg tcaaattttt aaaaaatcaa tagattaagg
       61 gatttaggat aacaaaatga cgaaaaaaat aatatttatc ttgttattct tcgtagtttg
      121 tgtttatttc tactccttta ttcccctcgt tcagactgtt ccatctgttt ttcagacacc
      181 ttatagaaca ttagttcaat ctgagtttga agcgatatat aaatataatg gtattgaaat
      241 ttcggaaagg aatttttgga ataaaccgat aaatggtcgt aaaccacaag atactctgaa
      301 tgaaaaagca acgatattat ttaaaaaata taatctttta gaaaaagaag cgaaaaaaca
      361 tgaatataaa aaagaggctc ttgatttcaa taaagttgat tggaagacag tctcaaatcg
      421 ctatattgaa ttaaaacaaa ttgttattga tgaaaaaatt aaagatataa atcaagatga
      481 gattgaacga tattacttag caaatactga aaattttgaa cgtcaagatt ttataagcgg
      541 taacatttct atatggaatg atgggataat tatttctact gaatcagtag atattaccga
      601 ggaaacagta agaaatataa ctgaaagata ccctgattta gaattagaat taaagaatat
      661 tgaagttggt catcaagttt cttggggaca gaatggggtt tattatacct ttacatgttt
      721 gtcgagagaa gaaaagggaa ttattccact ttctgaaatc acggatgcgg ttgctatgca
      781 atgtgcagag gaacttgttg ataattggtt aaataaagaa attgactctt taaaataatc
      841 cttgattatt gacaatctag agttaacaaa aattttttgt taatttaaaa ggaattggga
      901 attgtcgtac tgaaaaactg atttcaatta ttaagttaag tttcttagtt aaatactgta
      961 atttttgtag ccatactaat atatattttg taaaatagag ttacataaat ttattaagac
     1021 gaaacatttt ttatgtattt gtaactatgg gaggatgaag atgaagagca acaaagaaca
     1081 aaaatatttt tggttgacat tctcattgat tgttgcattg atgatttggt ggtttttatc
     1141 gaattatgat cgaacctctc gtagttttcc aaatatcatt ttggtttgga atgctttatt
     1201 aatcatgata gacaaaggat ttatctttga agatatattt tcaagtctaa cttcagtttt
     1261 cttcgggttc acgtcgggct ttctattgtc ggcgcctaat gcactcttaa tggcctggta
     1321 ttcaccttat cgtaatattg tgaaaccttg gatacaattt atcagaaata ttccacctct
     1381 tgcatacgtc cctttagttg taatttcagc tggggttggg ctattacctc aagttattgt
     1441 aatagcgata gctacttttc tgactatgac tgtaacaatt tatcaaggca ttattaatat
     1501 cgatccaaat ttaattaaag cagcaaggat tttaggagca tcagattttg aaatatttaa
     1561 aagaattttg gttccctcat ctattccatt tattatgaca gctgtcagat taggtacatc
     1621 gatttcttta acaactatca tagcagctga atctactggt gcaacatcag gtatgggaat
     1681 gagaatacgg tccttaaata actcttttga ttcctcggga atgcttttgt atatcatatt
     1741 gattggagtg attggtttac ttttaaataa gttagttgat ttgatagaaa ggaagttaac
     1801 tggatggcaa cagaagtaaa aaaaattaag gtcaaaattg aagatgtttc aaaatcattt
     1861 cagacaaatc atggtgaggt tgttgcacta aatcaaataa atttagaaat ctttgagaat
     1921 gaaatagtta cagttgttgg tccatctggt tgtggtaaat ctactctact aaacttggtt
     1981 gcaggtttgg aacctgtaac ttccggaaaa atttattgtg atgataatga aattgttggc
     2041 attggagttg agcgtggagt tgtttttcaa caatatgcat tatttccttg gatgagtgta
     2101 ctacagaatg taatgttcgg acctgaaatg caaggaaaat caaagttaga agctagtgaa
     2161 atagctaaca agtatattaa aatggttgga ttacaagaat tttccaatca ttatccgaaa
     2221 gaattatcgg gtggaatgaa gcaaagggtt gctatagcga gagcttatgc tgttaacccg
     2281 tcaattctat taatggatga gccctttgga gcattagatg cactaactag aattcagctt
     2341 caagaggagt tgattgaaat gttaggacaa gaacaaaaaa cttgtttttt cataacacat
     2401 gatattgaag aggcggtact attaggaaat cgagtgattg ttatgagtcc acgccctgga
     2461 gaaattaaag aaattgtgaa cgttgattta ccatttccaa gaaatcagtt gacaaagttt
     2521 gaaaaaaatt ttatggacat aaagaaccat atatggtcac ttgtttataa agattttcta
     2581 atataaaaaa gtgaaacagt agaattattt tgtgagaggg taaaatggct aaatatatga
     2641 aatataaaaa cttcatttgg tttatttgca gcataatcac tctgattttt ctttcttcgt
     2701 gtagttctat tcaaacctcc tctagtggcc attcagcaaa agttgacaca attagaattg
     2761 catatatgcc aaattttgca agtcttcatg acattataac tggaataaat tcaggtatct
     2821 ttaaagagga ggggcttgaa gtcgaattga ttgaatttgc tgatggtccg actatcattg
     2881 catctttaga gtcaggttca attgatattg gtaatattgg tccgggtgcc cataaattgg
     2941 cgattgaagg tagagcagaa gttgttgcat ttagtcaact tgggaatgct gacgaattga
     3001 ttgctcggtc ggatagagga attgattcaa tagaggattt gagaggaaag aaaattggaa
     3061 cagcatctgg gacatcagca gaaacaattc taaagcttgc tttgttagaa gcagatttgt
     3121 ctgaaaagga tgtagaaatt attgatatgg atgcctccgc tattgttaca gcaatgttgt
     3181 cgggttcaat tgatgtagct gcaacctggt caccaaatac aacttttata aagcgagaat
     3241 taaaggaaaa ggtcgttgta ctagctgata attcacgtta tagagaacaa tctccagcta
     3301 ttgcttcata cgtaactttt ccggggtatt ctgaaaaaaa taatgaaaaa atttccaagt
     3361 ttttaaaagg gttatatcgt gcaatggatt atcgagctga acatatgaag gaagtttcaa
     3421 aatgggttgc tacccaaatc ggttcagata tcacagctgt tcaagatcaa ctacaagatg
     3481 gagagtggtt aacaagtaga caaatgattc aattgattaa cactgggata cttcaacagt
     3541 attacgagaa acaacaaaaa aatttaatag
//
LOCUS       DBNFCO010000118         3474 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.119, whole genome shotgun sequence.
ACCESSION   DBNFCO010000118 DBNFCO010000000
VERSION     DBNFCO010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3474
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.119"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            18..857
                     /gene="licT"
                     /locus_tag="AC1PIV_001856"
     CDS             18..857
                     /gene="licT"
                     /locus_tag="AC1PIV_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009910435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HIP6612834.1"
                     /translation="MIIKRVLNHNAVIAQNNKNVDILLFGKGIAFGKKVGDAIPPSSI
                     EKSFLLKNSDNMNRFTELFIDVPIELVYVCEKIINLGKITLGNHFDEIIYINLTDHIN
                     SSIERHKEGVVVTNPLRWEIAKYYKEEFELGKKALSIIKKDLHVELPVDEAAFIALHF
                     VNANLENIFQESYRITGIIMKIEQIIQDYYSTEFNQDSIDYYRFITHVKLFAHRLVEG
                     NEYHDEDDVDLLELMKKKYPREYQCGTRVADFIRLEYDYLLSPSELVYLIAHIRRLTK
                     NLS"
     gene            868..2709
                     /locus_tag="AC1PIV_001857"
     CDS             868..2709
                     /locus_tag="AC1PIV_001857"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HIP6612835.1"
                     /translation="MKYKNTALAILGAVGGEKNVLRATHCVTRLRLELKDENIVSDER
                     VKSISGVIGIMKKNGQYQIILGNDVANYYKEFTALGKFDSDSVQQLKKANVLEQVIEY
                     IAGSMTPLIPAMLGGGMIKVLVIVLPMLGLLKADSQSISFLAFFGDAPYHFMPIFLAY
                     SASQKLKVTPALAMSVAGILLHPNFVQMVSSGDPLHFLGAPVTPASYGSSVIPILIMV
                     WLMKYIEAVFNKVTPAVTKSFLQPTLVLLVSGFIALVLVGPLGVIVGEGLSQLVEQMH
                     GVAGWLTLAVLGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     IAVAFKSKNSNTKQIAFAAGFSALFAGVTEPALYGVTLKYKKPLYAAMIGGGLAGLFV
                     GLTGVKAYLFAVPSLIALPQFIYSEAASNITNAMIAAAISIIVTFILAYFLGIDEETS
                     TVNLEKVAPGISSRKNVFSPLSGQILPLEKVNDATFSKKMLGEGVAIIPKDGKVYAPF
                     DGTVTSLFPTKHAIGLTSDEGVELLIHFGLETVELKGRGFVSHVSDGEKVEKGQLMLE
                     VDVEMLVAEGYDIVTPVVVTNTQEYLDVLLLSTKEEVNYADDLLAVL"
     gene            2724..>3474
                     /locus_tag="AC1PIV_001858"
     CDS             2724..>3474
                     /locus_tag="AC1PIV_001858"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HIP6612836.1"
                     /translation="MSIFPDNFLWGGAVAANQVEGAYNEGGKGLSVQDVLPNGGLGEA
                     TQEPTEDNLKLQAIDFYHRYKEDIALFSELGFKVFRTSIAWSRIFPNGDEEFPNEEGL
                     QFYDELFDELLKNGIEPLVTLSHYETPLYLARKYHGWVDRKMIQFFEKFARTVFERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDLPNEELSKQDLYQAIHHELVASSLVTKIAHEI
                     IPDCKVGCMVLAMPTYPMTPNPEDVWAAHAYE"
BASE COUNT         1067 a          567 c          721 g         1119 t
ORIGIN      
        1 agtttaaagg aaaatttatg atcataaagc gtgtattaaa tcataatgca gtcatagcac
       61 aaaataataa gaacgttgat atcttgttgt ttggtaaagg aattgcattt ggaaagaagg
      121 tcggagatgc gatcccacct tcttcgatag aaaaaagttt tttgctcaag aatagcgata
      181 atatgaatcg ctttacggaa ctatttatcg atgttcctat tgagttggtt tatgtttgtg
      241 agaaaataat aaatttagga aagataacac ttggaaatca ttttgatgag attatttaca
      301 tcaatttgac agatcatatc aattctagta tagaaagaca taaggaagga gtagtcgtta
      361 cgaaccctct tagatgggaa attgccaaat attataaaga ggagtttgaa ctggggaaaa
      421 aagcattatc catcataaaa aaagatttac atgtcgaact cccagttgat gaagcagcct
      481 tcatcgcttt gcattttgtc aatgcgaatt tggaaaatat ttttcaagaa tcttatcgta
      541 ttactggaat tatcatgaag attgaacaaa ttattcaaga ctattattct acagaattca
      601 atcaagattc tattgattac taccgattca tcacacatgt taagttgttt gctcatcgtt
      661 tggtagaggg gaatgaatac catgatgaag atgatgtgga tcttttagag ttaatgaaaa
      721 agaagtatcc aagagagtac caatgtggaa ctcgagtagc ggactttatt cggttagaat
      781 atgattatct actgagtcca agtgaattag tctatttaat tgctcacatt cggcgtttaa
      841 caaaaaattt atcataagga gtctattatg aagtacaaga atactgcatt ggcaatccta
      901 ggggcagtcg gaggagaaaa gaatgttctt cgtgcaaccc attgcgttac tagattgcga
      961 ctggaactga aagatgagaa tatcgtgtcc gatgaacgtg ttaaatccat ttccggagtc
     1021 attggcatta tgaaaaaaaa tggacaatat caaatcatct taggtaatga tgtagctaat
     1081 tactataaag aatttactgc attaggaaaa tttgattctg attcagttca acagcttaaa
     1141 aaagcaaatg tcttagaaca agtcatcgag tatatcgctg gctctatgac accacttatt
     1201 ccagctatgc ttggtggagg tatgataaaa gttctagtca ttgtcttacc gatgctgggg
     1261 cttttaaaag cggattccca atcaatttca tttttagcct tttttggaga tgcaccatat
     1321 cactttatgc cgattttttt ggcctactca gcttcacaaa aactcaaagt tacacctgct
     1381 ttagctatgt cggttgctgg tattttgcta catcctaatt ttgttcaaat ggtatcttca
     1441 ggtgatccac ttcatttttt aggtgcccct gttacacctg ctagctatgg ttcatcagtt
     1501 attccaattc ttattatggt ttggctaatg aagtatattg aagctgtttt taacaaggtc
     1561 actccagctg taacgaaaag tttcttacag ccaaccttgg tcctgcttgt ttcaggtttc
     1621 atagctttag ttcttgttgg acctctcggc gttattgttg gtgaaggatt atcgcaattg
     1681 gttgaacaaa tgcatggtgt agctggttgg ttaactttag cagttcttgg agcaatcatg
     1741 ccatttatcg ttatgaccgg tatgcactgg gcttttgcac cgattttctt ggcagcttca
     1801 atcgcgacac ctgatgtatt gattctacca gcgatgttag gttctaactt ggcacaaggt
     1861 gccgcttcta tcgcagttgc atttaagagt aaaaatagta acacaaaaca aatagccttt
     1921 gcagctggat tttcagcttt atttgctggt gtcactgagc ctgctttata tggtgttact
     1981 ctaaagtata aaaaaccatt gtatgcagca atgattggtg gtggtctagc aggattattt
     2041 gttggtttga caggtgtaaa agcatacctc tttgcagtac cttctctcat tgctttgcca
     2101 caatttattt actctgaagc agcttcaaac attactaatg ctatgattgc tgcggcaatt
     2161 tcaattattg tcacatttat tttggcctat ttcctaggta ttgatgaaga aacgtcaaca
     2221 gttaatttag aaaaagtagc acctggcatt tcaagtagaa aaaatgtctt ctctcctctt
     2281 tcaggtcaaa ttctcccttt agaaaaagta aatgatgcaa cgttttcaaa aaaaatgctt
     2341 ggagaaggag ttgcaattat ccctaaggat ggaaaagtct atgctccatt tgacgggact
     2401 gttaccagtc tttttccaac aaaacatgca atcggtttaa caagtgatga aggggtagag
     2461 ttgcttatcc actttggatt agaaactgtc gagctaaaag gaagaggttt tgtaagccat
     2521 gtttcagatg gggaaaaagt tgaaaagggt caactgatgc tggaagtgga tgtagaaatg
     2581 cttgtcgcag aagggtacga tatagtgact cctgtagttg ttacaaatac acaggaatat
     2641 ctggatgttc tcttgctttc gacaaaagag gaagtcaact atgctgatga tttattagca
     2701 gtcttataat tcgaggaggg tatatgtcaa tttttccaga taatttctta tggggaggag
     2761 cagtagctgc aaaccaagta gaaggtgcat ataatgaggg aggaaaagga ttatccgttc
     2821 aagatgttct ccccaatggt ggactgggtg aagctaccca agaaccaacg gaggataatt
     2881 tgaaattaca agctattgat ttttaccatc gatacaagga agatatagcc ctgttttcag
     2941 agttgggatt taaggtattt agaacatcaa ttgcttggag tagaatattt ccgaatggag
     3001 atgaagaatt tccaaatgaa gaagggctac agttttatga tgaacttttt gatgaacttc
     3061 taaagaatgg tatagagcct cttgtaactc tttctcacta tgaaactccc ctgtatctgg
     3121 caaggaaata tcatggctgg gtggatagaa aaatgattca attttttgaa aaatttgctc
     3181 gtacagtttt tgagcgatac aaagataagg ttaagtactg gttgacattt aacgaggtca
     3241 attctgtctt agaattgcct tttacaagtg gtggaattga cttgccgaat gaagaacttt
     3301 caaaacaaga tttatatcag gccattcacc atgaacttgt agcttctagt cttgttacca
     3361 aaattgctca tgaaattatt cctgactgta aggttggctg tatggtctta gctatgccga
     3421 cctatccaat gacacccaat cctgaagatg tttgggcggc tcatgcctat gaaa
//
LOCUS       DBNFCO010000119         3375 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.121, whole genome shotgun sequence.
ACCESSION   DBNFCO010000119 DBNFCO010000000
VERSION     DBNFCO010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3375)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3375)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3375
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.121"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(43..675)
                     /locus_tag="AC1PIV_001859"
     CDS             complement(43..675)
                     /locus_tag="AC1PIV_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HIP6612837.1"
                     /translation="MKEFKTIREDGIVEEEIKKSRFICFMKRVTSEEEARDFINKIKK
                     EHYKATHNCSAFVLGENMEIKRSSDDGEPSGTAGVPMLTVLENHELTNVATVVTRYFG
                     GIKLGAGGLIRAYAGAVANAVKEIGVVEVKEQEGISLSMSYAQYQEFANWRAEQGLEE
                     FDTQFTTEVSTMIFVDKEFLEQTLASLTDFYHGKVSTEKANSRIVEVPVY"
     gene            732..2024
                     /locus_tag="AC1PIV_001860"
     CDS             732..2024
                     /locus_tag="AC1PIV_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HIP6612838.1"
                     /translation="MKELENYYGRLFTKYQLTAKEREIAEKVPSITKKNNCFRCGTTF
                     EEENKLPNDAYYCRACLLLGRVRSDEKLYHFPQKDFPITKCLKWKGQLTDWQQRISDG
                     LVANVENNRATLVHAVTGAGKTEMIYHTVASVIDKGGAVCLASPRIDVCIELYKRLQN
                     DFSVPISLLHGESEPYFRTPLVVATTHQLLKFYQAFDLVLIDEVDAFPYADNPMLYRA
                     ADNAVKEAGVQVFLTATSTDELDKKVRTGKLSRLSLPRRFHGNPLVVPQKVWFSKFDD
                     TLKKNRLVPKLKKAIEEQRKSCFPLLIFVPEISKGQEFTKIMKKTFPEETIGFVSSQT
                     ENRLEIVEGFRKREITVLISTTILERGVTFPCVDVFVVQANHYLYTVSSLVQIAGRVG
                     RSMERPTGLLQFYHEGSTGAIEKAVAEIKQMNKEAGYV"
     gene            2017..2682
                     /locus_tag="AC1PIV_001861"
     CDS             2017..2682
                     /locus_tag="AC1PIV_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009909437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HIP6612839.1"
                     /translation="MSNCLLCGQAMKNKTRFSDLIFFSKEKSGICEECFSTFEEIAEQ
                     HCPHCYKNGESESCKDCQYWQNQGKPVVHTALYQYNQAMAHYFSRYKFQGDYVLRNIF
                     AKKLRIALSQFPDYTIVPIPISQKRLSERGFNQVEGLLDATNIPYQSLLGKYESQKQS
                     SKNRAERLEAKQMFYLLDEKEVPEKILLFDDIYTTGATIQLAVELFMKIGRKEIKTFS
                     LTR"
     gene            2759..3301
                     /gene="hpf"
                     /locus_tag="AC1PIV_001862"
     CDS             2759..3301
                     /gene="hpf"
                     /locus_tag="AC1PIV_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome hibernation-promoting factor, HPF/YfiA
                     family"
                     /protein_id="HIP6612840.1"
                     /translation="MIKFSIRGENLEVTEALRTYVEEKVAKIEKYFNEEQELNAKVNL
                     KVYRDKRAKVEVTIPVGAVTLRAEDISQEMYGSIDLVVDKIERQIRRNKTKIERKHRQ
                     KVATGQVFTDELVEQTGEEVKVVRTKQVDLKPMDMEEAVLQLELLGHDFFIYTDANDG
                     TTNVLYRREDGDLGLLEVRQ"
BASE COUNT         1144 a          625 c          672 g          934 t
ORIGIN      
        1 aaaaaggata atataaaaaa actatctcgc cgatagcttt ttttaataga caggtacctc
       61 aacgattcga gagttagctt tttccgtgga tacttttccg tggtaaaagt cagtgagact
      121 tgctaaggtt tgttcaagga attctttatc tacaaaaatc atggttgaaa cttcagtagt
      181 aaactgggta tcaaattctt ccagaccttg ctccgctcgc caattggcaa actcttggta
      241 ttgggcatag gacatgctaa gggaaatccc ttcctgctcc ttaacttcca caaccccgat
      301 ttccttgact gcattagcca cggctccagc gtaagcacga ataagtccgc ctgccccgag
      361 tttgatacct ccaaaatagc gggtaaccac cgttgcgaca ttggtcagtt cgtgattttc
      421 taaaaccgtc agcattggca caccagcagt accagacggc tccccatcat ctgaggaacg
      481 cttgatttcc atattttctc caaggacaaa agcagagcag ttatgagtag ccttgtaatg
      541 ctctttcttg attttgttga taaagtcgcg agcttcctcc tcgctggtca ctcgtttcat
      601 aaagcagata aatcgtgact ttttaatttc ttcttcaaca ataccatctt ctctaattgt
      661 tttaaattct ttcataacca aattgtacta atttttttaa aaactgacaa gaaattccga
      721 ataaataagt gatgaaagaa ttagaaaatt attatggaag attatttacc aaataccaat
      781 tgacagcaaa agaaagagaa atagcagaaa aagtgccaag tattacaaaa aagaataact
      841 gctttcgctg tggaacaact tttgaagaag aaaacaaatt gccaaacgat gcttattact
      901 gtcgagcctg cttgcttcta ggcagagtac ggtcagacga aaaactctat cattttcctc
      961 agaaagattt tccaatcact aagtgtttaa agtggaaagg tcaattaact gattggcaac
     1021 aaagaatttc agatggacta gttgcaaacg tggaaaataa tcgtgcgaca ttggttcatg
     1081 cagtaacagg agcaggtaag acagaaatga tctaccacac cgttgcctca gtgattgata
     1141 aaggcggagc ggtttgccta gccagtcctc gaattgatgt ttgtatcgaa ctctataaac
     1201 gtctgcaaaa tgacttttca gttccaatta gtttactaca tggagagtct gaaccctatt
     1261 tccgaacccc attagttgta gcaaccacac atcagttatt aaaattttat caggcctttg
     1321 atttggtttt gattgatgaa gtagacgcct ttccctatgc agataatccc atgctctatc
     1381 gagcagcaga caatgcggtc aaggaagctg gtgttcaagt ttttctgaca gcgacttcaa
     1441 cagatgaatt ggataaaaaa gtcagaacag gtaaattaag tcgtcttagt ttgccaaggc
     1501 gctttcatgg caacccactt gttgtcccgc aaaaagtctg gtttagtaaa ttcgatgata
     1561 ccctaaagaa aaatagacta gttccaaagt tgaaaaaagc gattgaagaa cagagaaagt
     1621 cgtgctttcc cttactcatt tttgtcccag aaatctccaa aggtcaagaa tttaccaaga
     1681 taatgaaaaa aacattccca gaagaaacaa ttggctttgt atccagtcaa acagaaaatc
     1741 gccttgaaat agttgaaggg tttcgcaaga gagaaatcac agtcttaatc tcgactacta
     1801 ttcttgaacg tggggtgacc ttcccatgtg tagacgtctt tgttgttcaa gccaatcatt
     1861 acctctacac agtgtcaagt cttgttcaga ttgcaggccg agtcggaagg agtatggaac
     1921 gtccgactgg tttactccag ttttatcatg agggaagtac aggagccatt gaaaaggcag
     1981 tcgctgaaat taaacagatg aacaaggagg ctggttatgt ctaattgcct attgtgcggt
     2041 caagctatga aaaataaaac aagattttca gatctcatct tctttagtaa agaaaaatcg
     2101 ggcatctgtg aagaatgttt ttcgactttt gaggaaatag cagagcaaca ctgtccacat
     2161 tgttataaaa atggggaatc ggaaagttgc aaggattgtc agtactggca gaatcaaggg
     2221 aaaccagttg tccacacagc tttgtaccaa tataatcaag cgatggcgca ttattttagt
     2281 cgctacaaat ttcaaggaga ctatgtttta agaaatattt ttgctaaaaa gcttagaata
     2341 gcgttaagcc aatttcctga ctacacaatt gttcccatac caattagtca aaaacgacta
     2401 tcagaacgcg gttttaatca agtggaagga cttttggatg ctacaaatat tccctatcag
     2461 tcccttcttg gaaagtatga aagccaaaaa caatcatcta aaaatcgtgc agagagacta
     2521 gaagcaaaac agatgttcta tctattagat gaaaaagaag tgccagaaaa aatattatta
     2581 ttcgacgata tatatacaac aggagccaca atccaacttg ctgtagaact tttcatgaaa
     2641 attggtagga aagaaatcaa aacattttca ctaacacgat aagaaaacga ttgcaatatc
     2701 cctataatgt ggtataataa tagtgaagaa aggcgaaagc caagaaagag gtactaatat
     2761 gattaaattc agtattcgtg gagaaaacct tgaagttaca gaagcacttc gcacctatgt
     2821 agaagagaaa gtggctaaga ttgagaaata tttcaatgaa gaacaagagt tgaatgctaa
     2881 agtaaatcta aaagtttacc gtgacaagcg tgcaaaagta gaagtgacaa ttccagttgg
     2941 agcagttaca cttcgcgcag aagatatttc acaagaaatg tatggctcta tcgatcttgt
     3001 agtagataag attgaacgcc aaattcgtcg taacaaaacc aagattgaac gaaagcatcg
     3061 tcaaaaagtg gcaactggtc aagtctttac agatgaactt gttgagcaaa caggcgagga
     3121 agtaaaagtg gttcgtacta agcaagtaga cttgaaacca atggatatgg aagaagcagt
     3181 cctccaattg gagttgctcg gacatgattt ctttatctat acagatgcta atgacggtac
     3241 aacaaatgta ttgtatagac gcgaagatgg agatttgggt cttctagagg tacgtcaata
     3301 aagataataa aacagttgca gtttttgcag ctgttttatc attttcaaaa aaccggttga
     3361 caatgtatat aagtc
//
LOCUS       DBNFCO010000120         3293 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.122, whole genome shotgun sequence.
ACCESSION   DBNFCO010000120 DBNFCO010000000
VERSION     DBNFCO010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3293
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.122"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(<1..386)
                     /locus_tag="AC1PIV_001863"
     CDS             complement(<1..386)
                     /locus_tag="AC1PIV_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2142 domain-containing protein"
                     /protein_id="HIP6612841.1"
                     /translation="MKIEKLFLRLAIPFLLISIFVMPVTKVPDEATHAFMSWNILFDS
                     PTSRDTEAMNELRAADFTYSEPEIHAVDSTEYSSLFTKIRDFSKDKLSIDFSLKSLMS
                     TPQLIGLVVGKLLYPSYGMMVTIGRL"
     gene            complement(383..1642)
                     /locus_tag="AC1PIV_001864"
     CDS             complement(383..1642)
                     /locus_tag="AC1PIV_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis C-terminal
                     domain-containing protein"
                     /protein_id="HIP6612842.1"
                     /translation="MKSRIVSPKIIFIWNLLGSVSSAAISIFLLLLVTRLLTELEADI
                     FSFAYAVANLFVIIASFQVRDYQATDVSKKFSFSQYLATRLITITIMLLLALSYIFLS
                     QYEFQKSACIFLICLYRGSDALSDVFQGLFQQNARLDIAGKSLFLRNSIVILTFGFGL
                     FITNNLLLSLIYLVISSYLFVFFFDVTNLFQFTRIIKEEINLKAIKNILLECLPLFIN
                     AFLLVTIYNQPKYALNTFFERGVIGTGVQRDFNILFMPVFSMNILLILFRPMITQLAI
                     YRRAGDYNQFKQYQKRIVKMVVGLAVLVLVGGIVLGIPALNILYGTNLNKYWLSFIIT
                     MLGGIASTFATICDNMLTVLRKQKYLVISFAISCLLSILISNPLVEYYGILGAAIAFV
                     SSMWTWFLISLVIYLKLQKHLNWEVQE"
     gene            complement(1675..>3293)
                     /locus_tag="AC1PIV_001865"
     CDS             complement(1675..>3293)
                     /locus_tag="AC1PIV_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="rhamnan synthesis F family protein"
                     /protein_id="HIP6612843.1"
                     /translation="VSNSHVSKDIVQYLQSERLIDFFIQRDNIGYDFAAWKEGLNQVT
                     FYQYDSVTLMNDTCFGPLWDLEDYYSQFDSDVDVDFWGMTNHLETKIDSVVVPEHLQS
                     YFMVFKKRILQSQAFVGFWSSVSELTDIQDVIKLYESQLTKILLSEGYSYKCALDTSI
                     CCKTLENSNITLEYPEVILKNNVPFIKIKSFTEYPDRIYSLLHLIRMKTKYPVELIER
                     HLRQIIIPGTSFIPQIRVSQTTETVRSSTSVLLHVHIESVSIFEEYIEELCKIADRCQ
                     LLITLPEADFSNKCSIVERCLFTYQLRAQIAKLTDELHFFEIVNNYMGDAKYLAHVTV
                     KQTKEIKYSVEDIIDRHQLRKMFFTSFDAVISNFESQSNLAVVIPDLTTNQRYDRQSL
                     REGNPELIRQLNILYESLVRTKKVDFYKVPYIIGEEVSWYWIKTEHYKKIEEKFRNID
                     FSKEDRLLLVPILFIYSAWDLSNDYAVVENTENVSPILEKISFSSERELRLIIEEKEF
                     LQIGLRRTLKIISVGIVSVFKMIKKSLLKN"
BASE COUNT         1157 a          617 c          440 g         1079 t
ORIGIN      
        1 aaaaggcgcc ctatagtgac catcatacca tatgacggat aaagcaattt acctacaact
       61 agaccaatta gctgaggtgt actcattaac gatttcagag aaaaatcgat agataatttg
      121 tcctttgaaa aatcacgaat tttggtaaaa aggcttgaat attctgtaga atcaactgca
      181 tgaatctccg gttctgaata cgtaaaatct gctgcccgta attcattcat tgcctcagta
      241 tctctacttg tcggagaatc aaataatata ttccacgaca taaaagcatg tgttgcttca
      301 tcaggaacct ttgtcacagg cataacaaat attgaaatta acaaaaaggg gattgctaac
      361 cttaaaaata atttttctat cttcattctt gtacttccca attcaaatgt ttttgcaatt
      421 ttagatatat tactaaagaa attaaaaacc aagtccacat cgaactaaca aaagcaatag
      481 ctgcccccaa tattccataa tattctacca atggattaga aatcaatatg gataataaac
      541 aagaaattgc aaatgaaatt acgagatact tttgcttcct caaaacagta agcatgttat
      601 cacaaatggt tgcaaaggta ctcgcaattc ccccaagcat tgttataata aagctgagcc
      661 agtatttatt aagattcgtt ccgtagagaa tatttaatgc tggaatcccc aatactattc
      721 ccccaaccaa aactaacaca gccaatccga caaccatttt aacgatacgc ttctgatatt
      781 gtttaaattg attatagtcc ccagctcttc tatatatagc caactgagtt atcatgggtc
      841 taaacaaaat caacaaaata ttcattgaaa aaacaggcat aaataaaata ttaaaatctc
      901 tttgaacacc tgttcctata acacctctct caaaaaaagt attgagagca tatttaggtt
      961 gattatagat agtaacaagt aaaaatgcat taataaataa cggcaaacat tctaataata
     1021 tatttttaat ggctttcaaa ttaatttctt ctttgataat cctcgtaaat tgaaacaaat
     1081 tcgtaacatc aaaaaagaaa acaaataaat atgagctaat tactagatag attaatgaga
     1141 gtagcaggtt attggttata aacaaaccaa atccaaatgt caaaatcaca atagagtttc
     1201 tcaaaaaaag tgatttacct gcaatatcta gccgagcatt ttgttggaac aatccttgaa
     1261 aaacatccga tagagcatca cttccacgat acaaacatat taggaaaata caagcagatt
     1321 tttgaaattc atattgagac agaaaaatat agcttaaggc aagtaatagc ataatagtga
     1381 ttgttataag ccttgttgca agatactggc taaacgaaaa ttttttcgaa acatcagtag
     1441 cttgataatc tcttacctga aaactagcaa tgattacaaa aagatttgct actgcatagg
     1501 caaaactaaa aatatcagcc tctaattccg tcaacaaacg tgttactagt aacaataaaa
     1561 atattgatat tgctgctgag gaaacacttc ctaataaatt ccaaataaat attatttttg
     1621 gtgatactat tctgctcttc acactttctt ccccttgttt gtcatccgtt atccctaatt
     1681 ttttaataga gatttcttta tcatcttaaa cacgcttaca attccaactg atattatctt
     1741 tagtgtcctt ctcagtccaa tttgtaaaaa ttccttctct tcaataatta aacgcaattc
     1801 tctttcacta gaaaaactaa tcttttccaa tattggactc acattttcag tattctcgac
     1861 cactgcataa tcgtttgata aatcccacgc gctataaata aataatattg gaactagcaa
     1921 taatctatct tcttttgaaa aatcaatgtt tctaaatttc tcctcaatct ttttatagtg
     1981 ttctgttttt atccaatacc aacttacttc ttctccaatt atataaggca ctttataaaa
     2041 atcaactttc ttagttctca caagtgattc ataaagtata ttcaattgac gaataagttc
     2101 tggattgccc tctcgaagac tttgtctatc atatctttga ttagttgtta agtctggaat
     2161 aactacagcc aaattagatt gtgattcaaa attagaaatc actgcatcaa atgatgtaaa
     2221 aaacattttc ctcaactgat gcctgtcaat aatatcctct acagaatatt ttatttcctt
     2281 tgtttgtttg acagttacat gagcaagata tttggcatct cccatatagt tgtttactat
     2341 ttcaaaaaaa tgcaattcat ctgtgagttt tgcaatctgt gctctcaatt ggtaggtgaa
     2401 taaacatctc tcaactatac tacacttatt tgaaaaatca gcttctggca atgttattag
     2461 taactggcac ctatcggcta ttttgcataa ctcttcaata tactcttcaa aaatagacac
     2521 tgattctatg tgaacatgaa gaagtaccga cgtcgaagaa cgaacggtct ctgtcgtttg
     2581 cgaaacccgt atttgaggaa taaaactcgt acccggaatg attatctgcc tcaaatgcct
     2641 ctcgattaat tcaactggat atttcgtttt catcctaata agatgtaata aagagtatat
     2701 tctgtctgga tattcggtaa aactctttat ttttatgaat ggaacattat ttttaagtat
     2761 aacttctgga tattctagtg taatgttgct attttcaagg gttttacaac aaatggacgt
     2821 atctaatgca cacttatagc tatagccctc tgataaaagt atttttgtca attggctctc
     2881 atataatttt ataacatctt gaatatctgt taactcactt accgatgacc aaaaaccaac
     2941 aaatgcttga ctctgcaaga ttcgtttttt aaataccata aaatatgact gtaaatgttc
     3001 cgggacaact acactatcta tttttgtctc taagtgattg gtcatccccc aaaaatctac
     3061 atcaacatca ctgtcaaatt gactataata atcctctagg tcccagaggg ggccgaaaca
     3121 tgtatcattc atcagagtta ccgaatcata ttgataaaat gttacttgat tcagcccttc
     3181 tttccatgcc gcaaaatcat aaccaatatt atctctttgg ataaaaaaat caatcagtcg
     3241 ttccgactgt aaatattgta ctatgtcctt tgaaacatgg ctgttagaaa caa
//
LOCUS       DBNFCO010000121         3277 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.123, whole genome shotgun sequence.
ACCESSION   DBNFCO010000121 DBNFCO010000000
VERSION     DBNFCO010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3277)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3277)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3277
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.123"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            16..195
                     /locus_tag="AC1PIV_001866"
     CDS             16..195
                     /locus_tag="AC1PIV_001866"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612844.1"
                     /translation="MKRKLFVFAWLALVLEMLIYYWYQLPALNILSVDFWIFFLQSVG
                     LVWLILSTFSSKGAF"
     gene            199..1677
                     /locus_tag="AC1PIV_001867"
     CDS             199..1677
                     /locus_tag="AC1PIV_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018165250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612845.1"
                     /translation="MTKISGRQRQVDTYQIKTSQLPAYLKWLGRIWVLVVLGLLGLGL
                     INSRVFRAKDYAAVISVKDADFKADFPETDISKLALLDRASAEKIGDTYLGTIDKVSQ
                     FGISDDYRQITIGQQPFRVSPLEYKNFWKWLSNHQDGIGYYVKVNQTTGKAELAKLSK
                     AMHYSDSEFLLNDTLRHLRLQYPTTIFGKPSFEVDDQGNPYYIATIYEPKFGLSSNDP
                     IGAIVLDAVTGESKKYGLEDIPEWVDRVYSANNVISRVDDHYTYQNGFWNTIFSQTGV
                     KNTTDSYNYISIGSDIYLYTGITSATADSSNLGFILVNMRTREITNYKLASATETAAQ
                     KSAEGEVQEKGYKATNPSLVKLADTAYYLVSLKDDAGLVKSYALVDAEDYQQVTVNND
                     IALLISQVTGTDASSLSGLTVTENGEVGEQTEVISGKVEALASQIIGGATIYYIESEG
                     KIYKVKATEDSTDRLPFIKVGDHFSGQLDKKNYLKNFKVNPE"
     gene            1837..3225
                     /locus_tag="AC1PIV_001868"
     CDS             1837..3225
                     /locus_tag="AC1PIV_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HIP6612846.1"
                     /translation="MSLFRKKQAVGRHSQMRRHLGLVDLIFLGIGSMVGTGIFTVTGL
                     AAAQYAGPALIISIVIAAISVGLTALFYAEFASRIPTNGGAYGYLYSVFGEFPAWIAG
                     WLTIMEFLTAVSSVASGWGAYLKGLLANFGIAMPTALNGTFNPAAGTYVDLLPVLVLI
                     FVVGVVLLNSKAALRFNSALVVLKFSALALFILVGLFFIKPENWSNFSPFGFGAIYGG
                     QAGIMAGASLMFFAFLGFESISLAIDEVKKPEKNVPKGIVLSLSIVTILYIVVTLVLT
                     GMVHYTKLNVADAVAFALREVGLDWAASYISIVAILTLITVCISMTYALSRMVYSISR
                     DGLLPKSLSRLTQTSKVPKNATILVGIFAAICAGIFPLASIASFLNICTLAYLIMLAL
                     GIIRLRQVEGLPKDGQFKTPLVPLLPILSIIICLSFMFQYSLDTWLAFGVSLVIGILI
                     YFCYGYRHSEAK"
BASE COUNT          883 a          600 c          724 g         1070 t
ORIGIN      
        1 gtcaaggagg ttattatgaa aagaaaatta tttgtttttg cctggttagc cctagttttg
       61 gaaatgctaa tctactactg gtaccagttg cctgctttaa atattttgag tgtggacttc
      121 tggatatttt tccttcaatc tgtcggattg gtctggctca tactttccac gttcagctcc
      181 aaaggtgctt tttaaaaggt gaccaagatt tccggtcgcc agagacaagt agatacctat
      241 cagattaaaa cctcgcaact accagcttac ttaaaatggt tgggacgaat ttgggtattg
      301 gttgtcctgg gtttgttggg gttggggctt atcaactcac gtgtatttcg tgctaaggat
      361 tacgctgctg tcataagcgt caaggatgcg gattttaaag cagattttcc tgaaacagac
      421 atatccaaat tggccctcct agatcgcgcc tcagccgaaa aaatcggtga tacttatcta
      481 ggtaccattg acaaggtctc ccagtttggc atttcggatg attatcgcca gattactatc
      541 ggtcagcaac cgttccgtgt atcgcctttg gaatataaga atttttggaa atggctgagc
      601 aaccatcaag atgggattgg ttactacgtg aaggttaatc agacaacagg gaaggcagaa
      661 cttgccaagt tgagcaaagc catgcactat tcagattccg aatttttgct gaatgatacc
      721 ttacgtcatc ttcgcctgca atacccgaca actatttttg ggaaaccatc cttcgaagtg
      781 gatgaccaag gaaatccata ttatattgca acgatttacg agccaaaatt tggactttca
      841 tcaaatgatc cgattggtgc tattgtattg gatgcagtaa caggcgaaag taagaagtat
      901 ggtctggaag atattccaga gtgggtagac cgtgtttatt cggcaaacaa tgttatcagc
      961 cgtgtagatg accactatac ttatcaaaat ggtttctgga ataccatttt cagtcaaact
     1021 ggtgtgaaaa atacaacaga cagctataat tatatttcta tcggctcaga tatttatctc
     1081 tacacaggta tcacctcagc aactgctgat tcatccaacc ttggatttat tcttgtcaat
     1141 atgagaactc gtgaaattac caactacaaa ttggcttcgg cgactgaaac agcagcgcag
     1201 aagtctgcag aaggtgaagt gcaggaaaaa ggctataaag ccactaatcc aagcctagtt
     1261 aagttggcag atacagccta ctatttagta tccttgaaag atgatgccgg cttggttaaa
     1321 tcatacgctc ttgttgatgc cgaagattat caacaggtta ctgttaacaa cgatattgcg
     1381 ctcttaattt ctcaagtcac aggaacggat gcttctagcc tttcaggatt gacggtgact
     1441 gaaaatggag aagttggtga acagactgag gttatcagtg gaaaagtaga agctttagcg
     1501 agtcaaataa ttggcggtgc gacaatctac tatattgagt ctgagggcaa gatttacaaa
     1561 gtcaaagcaa cggaagatag tacagatcga ttaccattta tcaaagtagg agatcacttt
     1621 agcggtcagt tagataagaa aaattatctt aaaaacttta aggttaatcc agaataatca
     1681 taagaaagag tgaggtagaa aagccttgct cttttgcttg tcgtcaccca tgcgaaatat
     1741 ttcaacttat ggtataatgg agtgttgtgg ttctttgaca ggaatccgta gattattctg
     1801 tcgagtatcc atattcttat tctgaaggag tattttgtga gtttatttag aaaaaaacaa
     1861 gcagtcggtc gccatagtca aatgcgtcgg catttaggct tagttgattt gatattttta
     1921 ggtatcggtt cgatggttgg aacaggtatc tttacggtaa ctggtttggc agcagcccag
     1981 tatgcagggc cagctctgat catctcaatt gttattgcag caatttcagt cggactaaca
     2041 gccttgtttt acgcagaatt tgcctcgcgt ataccgacta acggtggtgc ctatggttat
     2101 ctctactcgg tttttggtga atttcctgcc tggattgctg gctggctgac aatcatggaa
     2161 ttcttgactg ctgtatcgag tgttgcatct ggttggggag cttatttgaa aggactcctg
     2221 gctaattttg gtatcgctat gccgacagct ctgaatggaa cttttaaccc cgctgcaggt
     2281 acctatgtag acctcttacc agttctcgtc ttgatttttg tggtaggagt ggtcttgctt
     2341 aattctaagg cagctcttcg tttcaattca gccttggtag ttttgaaatt ttcagcgttg
     2401 gctttattta ttttagtagg gttattcttt atcaaaccag aaaactggtc gaacttctct
     2461 ccttttggtt ttggtgccat ttatggtgga caagcaggaa ttatggcagg agcgtctctc
     2521 atgttctttg ccttcctggg atttgagtct atttcattag caattgatga ggtgaaaaaa
     2581 cctgagaaga atgtaccaaa gggaatcgtg ttgtctctat ccattgtaac aattctttat
     2641 attgtagtga cattagtatt gactggtatg gttcactata ctaagttgaa tgtggcagat
     2701 gcggtagctt ttgcacttcg agaagttgga ttggattggg cagcgagtta tatttctatt
     2761 gtagcaatac taacattgat tacagtatgt atttcgatga cctacgcctt gtcgagaatg
     2821 gtctattcca tcagtcgtga tggtttgcta ccgaaatcat tgagccgatt gacacaaaca
     2881 agcaaggttc ctaagaatgc gaccattctt gtggggattt ttgcagccat ttgtgcaggt
     2941 atttttccac tagcaagtat tgcttccttc ctcaatatct gtaccttagc ttatttgatc
     3001 atgctggcgt tgggtattat tcgtctgcgt caagtcgaag gtttgccaaa agatggacaa
     3061 tttaaaacac ctcttgttcc cttgttacct atcctctcga ttatcatttg tctttcattt
     3121 atgttccagt atagtttaga tacttggtta gcattcggag tatccttggt tattggaatt
     3181 ttgatttact tctgttatgg ctatcgtcat tcggaagcaa aataatagat ttcccttctt
     3241 ttatttgaag ggattttttg tacaattttt ttataga
//
LOCUS       DBNFCO010000122         3272 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.124, whole genome shotgun sequence.
ACCESSION   DBNFCO010000122 DBNFCO010000000
VERSION     DBNFCO010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3272)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3272)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3272
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.124"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(111..1364)
                     /locus_tag="AC1PIV_001869"
     CDS             complement(111..1364)
                     /locus_tag="AC1PIV_001869"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HIP6612847.1"
                     /translation="MKRILFISPTTSMDNGAEKSIYYLMKYLIQLGHTVINVTHAIGG
                     EPQDKHEQLYKMIGVKNYYLPTIKWWWPDAPGGEILNREEATSYYRQNVQDIAEIIEQ
                     NEIDLVISNTVNVFQGAIAASCQKVPHFWLIHEFPKNEFAYYADKIDFIEEYSSELFS
                     VTGELNNFLTPLFNKKVHSFISYTEQETKVLKKGNQVRIVSVGRLTEGKNQLELIKAY
                     KTLNRLDIELVFIGGWDSKYKAICDEYIHENKLQKNVKFLGNLDNPWEEVTDRDICVF
                     PSSMETFGLVYVEAILRGLPVILSNNLGHLTAFEIFSAGQIYKLGDIEELVTKLEQVI
                     ESFRNFSDRARLDVERLRTLYTPEVAYKEILDGINHLEYTGHQNTNLSHIKELLTLNM
                     RPTRLERYARLISNMATKIRHKLRL"
     gene            complement(1364..>3272)
                     /locus_tag="AC1PIV_001870"
     CDS             complement(1364..>3272)
                     /locus_tag="AC1PIV_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="rhamnan synthesis F family protein"
                     /protein_id="HIP6612848.1"
                     /translation="LLALQRDKQRRNNYSDIKNRYLIYTIYEHQSSLQDYKVIFLEAL
                     AKISRDVLIVVNGKLPQADINRLAQFGKVLERDNEGYDVAAFRHGIIHTGKEALQQYN
                     QLILVNDTNIGPFRDLEEVFSEFNSDQLDFWGISMGEEQLDFTGYNPYGKIPKHLQSY
                     FVVIENSLLRYEGFYDYWEKLSDTDSRNKAIGKHETVFAKYFYDRGFKYDALIKDTKD
                     SALYIHPFKLLKQGCPLVKYSAFRNYDREQYFWHGLERESEIPDLMEYIAKETDYPIE
                     VVSSILEDFKTRENQSYILIIDGVENIIPQCTRYRVLNKAEQLRELGYTVRVINNSLV
                     QLQDAQFASHIIIYRAPFNDMLKEICRAAHIKNRPVYFDIDDLVFDTKFTDELEFTQG
                     LSKREKKGYDTSVLAYKKMLSLCDYAITSTSKLKDELEQYKNKVILNRNVMSKELVER
                     SLQVKKNSNDNKVKIGYFSGSITHNENFDLISQALLNLLQKYPQVELHIVGYLDIPKP
                     FQKFKKQIVSHEYVDWRKLPILISQVDINLAPLVTTTFNEAKSEIKWIEAAAVKVVTV
                     ASNLGAFEEMIQDGVTGVLADDNEWESKLERLILEQDLRAQIAENAFEFVMNHCTTAN
                     RINDFLKEELV"
BASE COUNT         1031 a          645 c          442 g         1154 t
ORIGIN      
        1 ctttcatttt ttctctctaa aactagaatt ctatataact ttttagattc tacttactca
       61 tttgaagaaa ctataatata catctttcag catagctatc ctattattca ttaaagtcga
      121 agtttatgtc tgatttttgt cgccatattg ctgatcaatc ttgcataacg ctccaatctt
      181 gttggacgca tatttaaagt cagtaactct tttatgtgac ttaaatttgt attttggtgt
      241 ccagtatatt ctaagtgatt gatgccgtcc agtatttctt tataggcaac ttccggtgta
      301 tatagagtac gtaaacgttc cacatcaagc cgagccctat ctgaaaaatt tctaaaggat
      361 tcaatcactt gctctaactt agtcaccaac tcttctatat cgcccaattt ataaatttga
      421 cctgctgaga atatttcaaa tgccgtcaaa tgtcccaaat tatttgatag aattactgga
      481 agccctctta agattgcttc aacatagact aagccaaaag tttccataga tgaggggaaa
      541 acacagatat ctctatcagt tacttcctcc caaggattat ctaagttacc taaaaattta
      601 acatttttct gtaatttatt ttcatggata tattcatcac aaatagcttt gtatttacta
      661 tcccatcctc caataaaaac caattcaatg tctaatctat ttagtgtctt atatgctttt
      721 ataagttcta attgattttt tccttctgtt aatcgaccaa cagaaacaat tctaacttga
      781 ttgccttttt ttaaaacttt tgtttcttgc tcagtataag aaataaacga atggactttc
      841 ttattaaata gtggtgttaa aaaattattt aactctccag tcacactaaa taattctgaa
      901 gaatactctt ctatgaagtc aattttatca gcataataag caaactcatt tttaggaaat
      961 tcatgaatta gccagaaatg aggaaccttt tgacatgagg cagcaattgc tccttgaaaa
     1021 acattaacag tatttgaaat aaccaagtct atctcatttt gctcaataat ttcagctatg
     1081 tcttgaacat tctggcgata gtagcttgtg gcctcttctc tattaaggat ttctccacct
     1141 ggtgcatccg gccaccacca cttaatagtt ggcaaatagt aattcttaac ccctatcatt
     1201 ttataaagtt gctcatgctt atcttgtggt tcccctccta ttgcatgagt aacatttata
     1261 actgtgtgtc ccagttgaat aaggtacttc attagataat aaatagactt ctccgcacca
     1321 ttatccatac tagtcgtagg agaaataaac aaaatacgtt tcattagact aactcttctt
     1381 tcaaaaaatc attaattcta tttgctgtag tgcaatgatt cattacaaac tcaaaagcat
     1441 tttctgctat ttgtgctctc aagtcttgtt caagaatcaa tctctccaat ttactttccc
     1501 attcgttatc atctgctaga actccagtca ctccatcttg aatcatctct tcaaatgctc
     1561 caagattact tgcaactgtc acaactttaa ctgctgccgc ttctatccat ttaatttccg
     1621 actttgcttc attaaaggtt gtggttacaa gcggcgccaa gttaatatca acttgtgaaa
     1681 ttaaaattgg aagctttctc caatcaacat actcatgact cacaatctgt tttttgaatt
     1741 tttggaatgg tttcggaatg tctaaatatc ctactatatg taattccact tgcgggtact
     1801 tttgaagtag atttagcaat gcttgactaa ttaaatcaaa attttcgttg tgtgtaattg
     1861 accctgagaa atatcctatt ttaactttat tgtcgttcga atttttctta acttgtaaac
     1921 tacgctcaac taattcttta gacatgacgt tgcgattcaa aataaccttg tttttatatt
     1981 gttcgagctc gtctttcaat ttcgaagtcg atgtgatagc ataatcgcag agagaaagca
     2041 tttttttgta agctaaaaca cttgtatcat agcctttttt ctctctcttg ctcaaacctt
     2101 gggtaaattc aagttcatct gtaaattttg tatcaaaaac caaatcatca atatcaaaat
     2161 aaacaggtct gttctttatg tgtgctgccc tacatatttc tttcagcata tcattgaatg
     2221 gagcacgata aataataata tgactagcaa actgtgcatc ctgaagttgt acaagagaat
     2281 tatttatcac tcgaactgta taaccaagtt ctcgcaattg ctcagcctta tttaacacac
     2341 gataacgtgt acattgtgga ataatatttt cgacaccatc aataatcaaa atataagatt
     2401 gattttctct agttttaaaa tcttctaata tagaagacac cacttcgatc ggatagtctg
     2461 tttccttagc aatatactcc atcaaatccg gaatctcgga ttctctttct aaaccatgcc
     2521 aaaaatattg ttctctgtca taatttctaa aggccgaata cttaactaat ggacaacctt
     2581 gttttaataa tttaaacgga tgaatataca atgcactatc tttcgtgtct ttaatcaatg
     2641 catcatactt aaagcctcga tcataaaaat attttgcaaa cacagtttca tgttttccaa
     2701 ttgccttatt acgagaatcc gtatcagaga gcttttccca ataatcataa aatccttcat
     2761 acctaagcaa gctattttca ataacaacaa aatatgattg taagtgctta ggaattttac
     2821 cataagggtt ataaccagta aagtctagct gctcctcacc catggaaatt ccccaaaagt
     2881 ctagctgatc ggaattaaac tcagagaaaa cctcttccaa atctctaaaa ggaccaatat
     2941 tcgtatcatt aaccaagatg agctgattat attgttgtaa cgcctctttt ccagtatgta
     3001 ttatcccgtg tcggaaagcc gcaacgtcat agccctcatt atctctttcc aaaaccttac
     3061 caaattgtgc taaacgattt atatcagcct gtggaagttt accatttaca acaattaaaa
     3121 catctcgaga aattttagcc aatgcctcta aaaaaattac tttatagtcc tgtaaagacg
     3181 attgatgttc ataaattgtg taaatcaagt aacgattttt gatatctgaa taattatttc
     3241 tacgttgctt atcacgttgc aaagctagta ga
//
LOCUS       DBNFCO010000123         3258 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.125, whole genome shotgun sequence.
ACCESSION   DBNFCO010000123 DBNFCO010000000
VERSION     DBNFCO010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3258
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.125"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            <1..1126
                     /locus_tag="AC1PIV_001871"
     CDS             <1..1126
                     /locus_tag="AC1PIV_001871"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HIP6612849.1"
                     /translation="VSFMLENNFALSRRGAVYFTLINFVLVYLFNVIIKQFKDSFLFS
                     TTYQKKTILITTAELWENMQVLFESDILFQKNLVALVILGTEIDKINLPLPLYYSVEE
                     AIEFSTREVVDYVFINLPSEYFDLKQLVSDFELLGIDVGVDINSFGFTVLKNKKIQML
                     GDHSIVTFSTNFYKPSHILMKRLLDILGAVVGLIICGIVSILLIPIIRRDGGPAIFAQ
                     KRVGQNGRIFTFYKFRSMFVDAEVRKKELMAQNQMQGGMFKMDNDPRITPIGHFIRKT
                     SLDELPQFYNVLIGDMSLVGTRPPTVDEFEKYTPSQKRRLSFKPGITGLWQVSGRSDI
                     TDFNEVVRLDLTYIDNWTIWSDIKILLKTVKVVLLREGSK"
     gene            1161..2330
                     /gene="cps2T"
                     /locus_tag="AC1PIV_001872"
                     /gene_synonym="wchF"
     CDS             1161..2330
                     /gene="cps2T"
                     /locus_tag="AC1PIV_001872"
                     /gene_synonym="wchF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta 1-4 rhamnosyltransferase Cps2T"
                     /protein_id="HIP6612850.1"
                     /translation="MRTVYIIGSKGIPAKYGGFETFVEKLTEYQKDKSINYFVACTRE
                     NSAKSDITGEVFEHNGATCFNIDVPNIGSAKAILYDIMALKKSIEIAKDRNDTSPIFY
                     ILACRIGPFIYLFKKQIESIGGQLFVNPDGHEWLREKWSYPVRQYWKFSESLMLKYAD
                     LLICDSKNIEKYIHEDYRKYAPETSYIAYGTDLDKSRLSPTDSVVREWYKEKEISEND
                     YYLVVGRFVPENNYEVMIREFMKSYSRKDFVLITNVEHNSFYEKLKKETGFDKDKRIK
                     FVGTVYNQELLKYIRENAFAYFHGHEVGGTNPSLLEALSSTKLNLLLDVGFNREVGEE
                     GAKYWNKDNLHRVIDSCEQLSQEQINDMDSLSTKQVKERFSWDFIVDEYEKLFKG"
     gene            2334..>3258
                     /locus_tag="AC1PIV_001873"
     CDS             2334..>3258
                     /locus_tag="AC1PIV_001873"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HIP6612851.1"
                     /translation="MKKILYLHAGAELYGADKVLLELIKGLDKNEFEAHVILPNDGVL
                     VPALREVGAQVEVINYPILRRKYFNPKGIFDYFISYHHYSKQIAQYAIENKVDIIHNN
                     TTAVLEGIYLKRKLKLPLLWHVHEIIVKPKFISDSINFLMGRFADKIVTVSQAVANHI
                     KQSPHIKDDQISVIYNGVDNKVYYQSDARSVRERFDIDEEALVIGMVGRVNAWKGQGD
                     FLEAVAPILEQNPKAIAFIAGSAFEGEEWRVVELEKKISQLKVSSQVRRIDYYANTTE
                     LYNMFDIFVLPSTNPDPLPTVVLEAMACGKPV"
BASE COUNT         1104 a          463 c          651 g         1040 t
ORIGIN      
        1 agtttcattt atgttagaga ataatttcgc actttcaaga cgtggtgccg tgtatttcac
       61 attaataaac ttcgttttgg tatacctatt taacgtaatt attaagcagt ttaaggatag
      121 ctttctattt tcgacaacct atcaaaaaaa gacgattcta attacaacgg ctgaactatg
      181 ggaaaatatg caagttttat ttgaatcaga tatactattt caaaaaaatc ttgttgcatt
      241 ggtaatttta ggtacagaaa tagataaaat taatttacca ttaccgctct attattctgt
      301 tgaagaagct atagagtttt caacaaggga agtggtcgac tacgtcttta taaatttacc
      361 aagtgaatat tttgacttaa agcaattagt ttcagacttt gagttgttag gtattgatgt
      421 aggcgttgat attaattcat tcggttttac tgtgttgaag aataaaaaaa tccaaatgct
      481 aggtgaccat agcatcgtca ctttttccac aaatttttat aagcctagtc acatcttgat
      541 gaaacgactt ttagatatac ttggagcagt agtcgggtta attatttgtg gtatagtttc
      601 tattttgtta attccaatta ttcgtagaga tggtggacca gccatttttg ctcagaaacg
      661 agttggacag aatggacgca tatttacatt ctacaagttt cgttcgatgt ttgttgatgc
      721 cgaggtacgt aagaaagaat taatggctca aaaccagatg caaggtggga tgttcaaaat
      781 ggacaacgat cctagaatta ctccaattgg acacttcata cgaaaaacaa gtttagatga
      841 gttaccacaa ttttataatg ttctaattgg agatatgagt ctagtcggta cccgtccgcc
      901 tacagttgat gaatttgaaa aatatactcc tagtcaaaag agaagattga gttttaaacc
      961 agggattaca ggtctttggc aagtgagcgg aagaagtgat atcacagatt ttaatgaagt
     1021 cgttaggctg gacctaacat acattgataa ttggaccatc tggtcagaca ttaagatttt
     1081 attgaagaca gtgaaagttg tattgttgag agagggaagt aagtaagact cctttaaaac
     1141 aaagaatagt agtaggggat atgagaacag tttatattat tggttcaaaa ggaataccag
     1201 caaagtatgg tggtttcgag actttcgtag aaaaattaac tgagtatcag aaagataaat
     1261 caattaatta ttttgttgca tgtacaagag aaaattcagc aaaatcagat attacaggag
     1321 aagtttttga acataatgga gcaacatgtt ttaatattga tgtgccaaat attggttcag
     1381 caaaagccat tctttatgat attatggctc tcaagaaatc tattgaaatt gccaaagata
     1441 gaaatgatac ctctccaatt ttctacattc ttgcttgtcg gattggtcct ttcatttatc
     1501 tttttaagaa gcagattgaa tcaattggag gtcaactttt cgtaaaccca gacggtcatg
     1561 aatggctacg tgaaaagtgg agttatcccg tccgacagta ttggaaattt tctgagagtt
     1621 tgatgttaaa atacgctgat ttactaattt gtgatagcaa aaatattgaa aaatatattc
     1681 atgaagatta tcgaaaatat gctcctgaaa catcttatat tgcttatgga acagacttag
     1741 ataaatcacg cctttctccg acagatagtg tagtacgtga gtggtataag gagaaggaaa
     1801 tttcagaaaa tgattactat ttggttgttg gacgatttgt gcctgaaaat aactatgaag
     1861 taatgattcg agagtttatg aaatcatatt caagaaaaga ttttgttttg ataacgaatg
     1921 tagagcataa ttccttttat gagaaattga aaaaagaaac agggttcgat aaagataagc
     1981 gtataaagtt tgttggaaca gtctataatc aggagctgtt aaaatatatt cgtgaaaatg
     2041 catttgctta ttttcatggt cacgaggttg gaggaacgaa cccatcttta cttgaagcac
     2101 tttcttctac taaactaaat cttcttctag atgtgggctt taatagagaa gtaggggaag
     2161 aaggagcgaa atactggaat aaagataatc ttcacagagt tattgacagt tgtgagcaat
     2221 tatcacaaga acaaattaat gatatggata gtttatcaac aaaacaagtc aaagaaagat
     2281 tttcttggga ttttattgtt gatgagtatg agaagttgtt taaaggataa gttatgaaaa
     2341 agattctata tctccatgct ggagcagaat tatatggggc agataaggtt ctcttggaac
     2401 ttataaaagg cttagataag aatgaatttg aagcgcatgt tatcctacct aatgatggag
     2461 tcctagtgcc agcattaaga gaagttggtg cgcaagttga agttattaac tatccaattc
     2521 tacgtaggaa atattttaat ccaaaaggga tttttgacta cttcatatca tatcatcact
     2581 attctaaaca gattgctcaa tatgccatag aaaataaggt tgacataatt cacaataata
     2641 ctaccgctgt cttagaaggc atttatctga agcgaaaact caaattacct ttgttgtggc
     2701 atgttcatga gattattgtc aaacctaaat tcatctctga ttcgatcaat tttttaatgg
     2761 ggcgttttgc tgataagatt gtgacagttt cacaggctgt ggcaaaccat ataaaacaat
     2821 cacctcatat caaagatgac caaatcagtg taatctacaa tggggtagat aataaagtgt
     2881 attatcagtc cgatgctcgg tctgttcgag aaagatttga cattgacgaa gaggctcttg
     2941 tcattggtat ggtcggtcga gtcaatgcgt ggaaaggaca aggagatttt ttagaagcag
     3001 ttgctcctat actcgaacag aatccaaaag ctatcgcctt tatagcagga agtgcttttg
     3061 aaggagaaga gtggcgagta gtagaattag aaaagaagat ttctcaatta aaggtctctt
     3121 ctcaagtcag acgaattgat tattatgcaa ataccactga attatataat atgtttgata
     3181 tttttgtact tccaagtact aatccagacc ctctaccaac ggttgtacta gaagcaatgg
     3241 catgcggtaa acctgttg
//
LOCUS       DBNFCO010000124         3200 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.126, whole genome shotgun sequence.
ACCESSION   DBNFCO010000124 DBNFCO010000000
VERSION     DBNFCO010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3200)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3200)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3200
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.126"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            92..1117
                     /gene="adhP"
                     /locus_tag="AC1PIV_001874"
     CDS             92..1117
                     /gene="adhP"
                     /locus_tag="AC1PIV_001874"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HIP6612852.1"
                     /translation="MKAVVVNPESTGVVVVEKELRPLEAGEALVQIEYCGVCHTDLHV
                     ANGDFGKVPGRVLGHEGIGIVTEIAPGVTSLKVGDRVSVAWFFQGCGMCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPEGLDPAQASSITCAGVTCYKAIKEAHL
                     EPGQWIAIYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLELAKEVGADVTINGLEVE
                     DVPGYIKEITGGGVHSTVVTAVSKVAFNQAIDSVRAGGYVVAVGLPSEYMDLSIVKTV
                     LDGIKVVGSLVGTRKDLEEAFHFGAMGLVVPVVQKRPVEDAEAVFNEMVAGTIQGRMV
                     LDFCHSH"
     gene            complement(1198..2481)
                     /gene="hisS"
                     /locus_tag="AC1PIV_001875"
     CDS             complement(1198..2481)
                     /gene="hisS"
                     /locus_tag="AC1PIV_001875"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HIP6612853.1"
                     /translation="MKLQKPKGTQDLLPQDSAKWQYVENFTRSIFKQYNYAEIRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGERHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PAKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSNNPATDVETIAMAYHFFEELGIKD
                     IRLHLNSLGNPESRAAYRQALIDYLTPLKEQLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDYLDEESTVHFEAVRSMLDNLGITYTIDTNMVRGLDYYNHTIFEFMTEVG
                     GNDLTICAGGRYDGLVTYFGGPETPAFGFGMGIERLILVLEKQGIELPLDTQLDVYIA
                     VLGQEANGGALDLVQAIRKQGFRAERDYLDRKLKAQFKSADVFGAKAIITLGGSEIES
                     GQVVVKNNQTRSQVETSLEALKTDFASILEELEKQ"
     gene            2757..2939
                     /gene="rpmF"
                     /locus_tag="AC1PIV_001876"
     CDS             2757..2939
                     /gene="rpmF"
                     /locus_tag="AC1PIV_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HIP6612854.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVAAPTVKFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            2955..3104
                     /gene="rpmG"
                     /locus_tag="AC1PIV_001877"
     CDS             2955..3104
                     /gene="rpmG"
                     /locus_tag="AC1PIV_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HIP6612855.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVI
                     FTEVK"
BASE COUNT          902 a          698 c          691 g          909 t
ORIGIN      
        1 ttgttcacat tgtgatattc ttaacaatat aaaacaacta tattaacaca tccaaaaatg
       61 tacataaaat attaaaacag gaggtctgct tatgaaagca gtcgttgtaa atccagaatc
      121 tactggtgtt gtcgttgtcg aaaaggaact tcgtccactc gaagctggtg aggctttggt
      181 ccaaattgag tactgtggtg tttgtcacac tgacctccac gttgccaatg gtgattttgg
      241 taaggttcct ggtcgcgttc ttggtcacga aggaatcggt attgttacag aaatcgcacc
      301 tggtgttacc agtctaaaag ttggtgaccg tgtcagcgtt gcttggttct tccaaggctg
      361 tggtatgtgt gaatattgta caaccggtcg cgaaactctc tgccgtaccg taaaaaatgc
      421 aggctactct gttgacggtg gtatggctga gcaatgtatt gtaacagcgg actatgcagt
      481 aaaagttcca gaaggtcttg atccagctca agcaagttct atcacttgtg ctggcgttac
      541 ttgctacaaa gcgattaaag aagctcactt ggaaccaggt caatggattg ctatctatgg
      601 tgctggtgga cttggaaacc ttgctgtaca atacgctaaa aaagtcttca acgctcatgt
      661 tatcgccgta gacatcaata atgataaatt ggaactcgcc aaagaagttg gtgcagatgt
      721 gacgatcaac ggacttgaag tagaagatgt tcctggatat attaaagaaa ttactggtgg
      781 cggtgtacac tctactgttg taacagctgt ttccaaagta gccttcaacc aagctattga
      841 cagtgttcgc gctggtggat atgtagtagc tgtcggactt ccatctgaat acatggacct
      901 cagtatcgtg aagactgtgc tagacggtat caaagtggtc ggctcactag ttggtactcg
      961 taaagattta gaagaggcct tccacttcgg tgctatggga ctagttgttc cagtcgttca
     1021 aaaacgccct gtcgaagatg ccgaagcagt cttcaatgaa atggttgccg gtactatcca
     1081 aggtcgtatg gtcttagact tctgccactc acactaatgc gttctccact attttcaaga
     1141 agtgattatc caatcgcttc ttttttgctt tctaaaataa aaagaagcag ctttagacta
     1201 ctgcttctcc aattcttcta aaatacttgc aaaatctgtt ttaagtgctt ccaagcttgt
     1261 ttcaacttga cttcttgtct ggttattttt gaccacaacc tgtccagatt caatttcgct
     1321 accacccagg gtaatgatag ccttggctcc aaagacatct gctgacttaa actgggcctt
     1381 gagcttgcgg tccagatagt cacgttctgc acggaaacct tgcttgcgaa tggcttgaac
     1441 aagatcaagc gctccgccat tggcctcctg acccaaaacc gcgatgtaaa catctaactg
     1501 ggtatcgaga gggagctcga tgccttgctt ttcaaggact aggatgaggc gctcaatgcc
     1561 cataccaaag ccaaaagctg gcgtttctgg tccaccaaag taggtcacca aaccgtcgta
     1621 acgtccaccg gcacagatgg tcaggtcatt gccacccact tctgtcataa actcgaaaat
     1681 agtatggtta tagtagtcca aaccgcgtac catgttggtg tcaattgtgt aagtaatgcc
     1741 taggttgtcc agcatggacc tgactgcctc gaagtggact gtactttctt catctagata
     1801 gtccaagatg gacggtgcat tttccacagc aaccttgtct tctttttcct tggaatccaa
     1861 cacacgcaaa ggattttctt ctagacggcg ctggctatct ttagacaact gttccttgag
     1921 cggcgtcaga tagtcaatca aagcctgacg gtaggcagca cggctctctg gattgcccag
     1981 actgttgagg tggaggcgaa tgtccttgat ccccaactct tcaaagaagt gataggccat
     2041 agcaatggtt tctacgtctg tcgctgggtt attggaacca aagcactcca caccaatctg
     2101 gtggaactga cggagacgac ctgcctgcgg acgctcatag cggaacattg ggcccatgta
     2161 atagaactta gcaggttttt gtacttctgg agcaaacagc ttgttctcta cataggagcg
     2221 aacaaccggt gccgtccctt ctggacggag ggtgatatga cgctctccct tgtcatagaa
     2281 atcgtacatc tccttggtca caatgtccgt cgtatcgcca accgaacggc tgatcacctc
     2341 gtaatgctca aagattggtg tgcgaatctc agcgtaattg tactgtttga aaatgctgcg
     2401 ggtaaagttt tccacgtact gccatttggc agaatcctgc ggtagtaaat cctgtgttcc
     2461 ctttggtttt tgtagtttca taataaagtg tatagagcca acttatatcg ctcgaagttg
     2521 tgcttcttcc tttccaaatt aagtcataag ggctcaaact ctaccagtcg agccttgcaa
     2581 tcctccttat tttaccataa atgctctgct attttccaaa aaagtgaaaa aaatctgtca
     2641 agtaacttta ctttacaaaa aacttttgtt atactgttaa agttggcgaa agtcatacgc
     2701 actattttta gatttaaaaa gggcttgacc ctgacattta atggaggaag aaagaaatgg
     2761 cagtacctgc acgtcgcact tcaaaagcga agaaaaacaa acgtcgtact cactataaag
     2821 tagcagctcc aactgtgaaa tttgatgaaa ctactggaga ttactcacgt tcacaccgtg
     2881 tatctttgaa aggatactac aaaggacgta aaattgccaa ggctgcttca gctgaataat
     2941 agaagggaga taccatgcgc gtaaatatta cacttgaaca caaagaatct ggtgagcgtt
     3001 tgtaccttac ttcaaaaaac aaacgtaaca ctccagaccg tcttcaattg aaaaaatact
     3061 caccaaaatt gcgtaagcac gtgattttta ctgaggtaaa ataagacaac atacagaaag
     3121 cctatgaaat caacgtttca aaggcttttt tcttttgttt ttgacaaaat aactgaattt
     3181 taactgatta aaataaatca
//
LOCUS       DBNFCO010000125         3107 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.127, whole genome shotgun sequence.
ACCESSION   DBNFCO010000125 DBNFCO010000000
VERSION     DBNFCO010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3107
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.127"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            14..1213
                     /locus_tag="AC1PIV_001878"
     CDS             14..1213
                     /locus_tag="AC1PIV_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012774923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HIP6612856.1"
                     /translation="MGKKEETIRNISGNILKTLFRHQKSSRTRISKSLKITPATITNM
                     ISYLVAEKKVIETGDEVRDYIGSGRSRRLITVNSQYRHYIGIEINANGIYLAVTDTIG
                     NLITNSNIKITEYDSKQINEIIIQLVTETLDKFSYLEFGALGIAVPGHFDSKSGHIIS
                     NNVKWIYFDLAVIKQSISIPIFLENNINCMAIGSYLFHPESSPEQFLFIHIGPGLFCS
                     FFDSEHILQNKNFYIGEIGHTVVDLNGPSCECGKRGCLQTYISDTWLINNARFLFENV
                     QGSIIKTLVEKPEDITLDVVYNAYRLGDGFIIEKIESGIDFLTTSIANTLIIYDSKKI
                     FINSQLLNYPGFSEKVNNLVDNQLQFIPSKNNLDIEFLSFNIFRGAIGAASLAVYNHF
                     ILENNSN"
     gene            complement(1496..2134)
                     /locus_tag="AC1PIV_001879"
     CDS             complement(1496..2134)
                     /locus_tag="AC1PIV_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III domain-containing protein"
                     /protein_id="HIP6612857.1"
                     /translation="MRWGIVVEQLTVLYQNLKRRYGEFHWWNDENPIKDLVSMILIQQ
                     TTEANAKRALEQLEGRLTIHSLLEMPVEDLQECIRPAGFFKQKSLYIRSVVEWANQFD
                     GDFSRLDRVETAVLRKELLSLKGVGNETADVILLYLCRRSVFVADQYALRLFNRLGLS
                     QSQDYLSLRQEFTEQIKDWSVKDAQELHALIDEHGKQFRLTKGQLDESWLMI"
     gene            complement(2182..3102)
                     /locus_tag="AC1PIV_001880"
     CDS             complement(2182..3102)
                     /locus_tag="AC1PIV_001880"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008443 - phosphofructokinase activity
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase family hexose kinase"
                     /protein_id="HIP6612858.1"
                     /translation="MIHLICPNPALDRTLLVEKIEKNIPLRPTEVRDYPGGKSFNVAY
                     ALRENGVTDYTIHTILGGQIGRYIQELNADGGNALRVVENSQNTRTCNIYVETSTGDV
                     VLFYEKGFELTEDLLNQFTQQIENSLQAGDILVFSGSLMKGMSDDYIQRFIEKYPEVL
                     TIVDTSGPALRAAYQARPALIKINNEELKDIYPELDEESPEAILGILKEVTPHENIII
                     TMGDKGSLAKIGQRFFRIQSPKKETRNPIAAGDFYLGLLVKGISQGQAPEIFLKEAAA
                     FATANCLNYFPEVEAEQFEAIVDTIVLEEL"
BASE COUNT          978 a          619 c          530 g          980 t
ORIGIN      
        1 gtgaggtact aaaatgggaa aaaaagaaga aaccattcga aatatttctg gaaatatatt
       61 aaaaacttta tttagacatc aaaaaagctc tagaacaaga atttctaaat ctttaaaaat
      121 tacaccggca actattacga atatgattag ttacctggta gctgaaaaaa aagttattga
      181 gactggcgat gaggttcgag attatattgg atcaggtcgt agtagacgac ttattacagt
      241 aaactctcaa tatagacatt atattggaat cgagattaat gccaatggaa tctatttagc
      301 cgtcacagac actattggaa acctaatcac aaatagcaat ataaaaatta cagaatatga
      361 ttccaaacaa ataaatgaaa taattatcca attagtaact gaaactctag ataagttttc
      421 ctatcttgaa tttggagctc tcggtattgc tgtacctggt cactttgatt caaaatcagg
      481 acatattatt tcaaataatg taaagtggat ttattttgat cttgccgtaa ttaaacaaag
      541 tatttcaatt cctatttttc tagagaacaa tattaattgc atggcaattg gttcatatct
      601 ctttcatccc gaaagttcgc cagagcagtt tttatttatt catattggac ctggattgtt
      661 ctgttcattt tttgatagtg aacatatttt acaaaacaaa aacttttata ttggagagat
      721 tggtcataca gtagttgatt taaacggacc ttcttgtgaa tgtggaaaac gtggatgcct
      781 tcaaacttat atttctgata cttggttaat caataatgca agatttttat ttgagaatgt
      841 tcaaggttct atcataaaaa ctttggttga aaaaccagaa gatattacat tagatgttgt
      901 atacaatgca taccgactag gagatggttt tattattgaa aaaattgaat cagggattga
      961 ttttttaact acctcaatcg caaatacatt gatcatttat gattcaaaaa aaatttttat
     1021 taatagccag ttattaaatt atccaggttt ttcagaaaaa gttaataatc ttgttgacaa
     1081 tcaattgcaa tttattccaa gtaaaaataa tttagatatt gaattcttat cttttaatat
     1141 atttcgaggt gcaattggag cagcatcctt agcagtctat aatcatttta tcttggaaaa
     1201 taactccaat taatataaaa aaagagcaac caactgaacc gctggtttta ctcttttata
     1261 gtcgtttcgt ttgcttttag tacaaggcaa cgatatgcag gctacttcaa ctgtccagtg
     1321 gagtgtttaa actcggaaat aaggaaatga gacttcctcg cccttcagta ataaaaaata
     1381 cactaattga tactcaatga aaatcaaaat caagctaggc gatgcaaatg cagatagaac
     1441 tgaggttcat caaatcatgt caacaacgtc tgattttgat tttcgaagag tatgactata
     1501 tcatcaacca tgattcatca agctgcccct ttgttaacct gaactgcttg ccatgttcat
     1561 caatcagtgc atgaagctcc tgagcgtctt ttaccgacca atcttttatc tgctctgtaa
     1621 attcctgtct caaactcaaa taatcctgag actggctaag tcctaaacga ttaaatagcc
     1681 gaagagcata ttgatccgcc acaaaaacac ttcttcgaca caaatagagc aaaataacat
     1741 ccgcagtttc attgccaacc cccttcaagc tcagcagctc ttttcggagt actgctgtct
     1801 caacacgatc taggcgagaa aaatctccat cgaactgatt ggcccactca accactgacc
     1861 gaatgtagag tgatttttgc ttgaagaatc ctgctgggcg aatgcattct tgtaaatcct
     1921 ccacaggcat ctctaaaagc gaatgaattg tcaaccgtcc ctccaactgt tctaaagcac
     1981 gcttggcatt tgcttccgtt gtttgctgaa taaggatcat agataccaaa tcctttatag
     2041 gattttcatc attccaccag tgaaattcac catatcgccg ttttaaattt tggtaaagaa
     2101 ccgtcaactg ttccactact atcccccatc tcaccttgtt tctccttgcc attatagcac
     2161 gatgagtaaa gggatacaat actacagttc ctctagtact attgtatcta caatcgcttc
     2221 aaactgctct gcttcaacct ctggaaaata attcaaacaa ttggctgttg caaaggctgc
     2281 cgcttctttc aaaaagattt ctggggcttg accttgactg attcctttga ctagcaagcc
     2341 caggtagaaa tcccctgcgg caataggatt acgcgtttct ttctttggag actgaatacg
     2401 gaagaagcgc tgaccaatct tagctagact ccccttgtct cccatggtaa tgatgatatt
     2461 ctcatgagga gtcacttctt tcaggatacc taaaatagct tcaggacttt cttcatccag
     2521 ctctggataa atatctttca gctcttcatt attgattttg ataagggccg gtctagcttg
     2581 ataagccgca cgtaaagctg gtccactggt gtccactatg gtcagaacct ctgggtattt
     2641 ttcaataaac cgctgaatat aatcatccga catccccttc atcagactac ctgaaaagac
     2701 taggatgtcg ccagcttgca ggctattttc aatctgctga gtgaattggt tgagcaaatc
     2761 ctctgttagt tcaaaacctt tttcataaaa tagtactaca tcgcctgtac tggtttcaac
     2821 atagatatta catgtccgag tattctggct attttcaacc acgcgcaggg catttccacc
     2881 atcagcatta agctcctgaa tatagcgacc aatctgccca cctaaaatgg tatggatagt
     2941 gtagtctgtc actccatttt ctcgaagtgc ataggctacg ttgaaacttt ttccaccagg
     3001 ataatccctc acttccgtcg gtctcagggg aatattcttt tcaatctttt ccacaagaag
     3061 cgtgcggtct agggctggat tgggacaaat caagtgaatc atggggt
//
LOCUS       DBNFCO010000126         3083 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.128, whole genome shotgun sequence.
ACCESSION   DBNFCO010000126 DBNFCO010000000
VERSION     DBNFCO010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3083)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3083)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3083
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.128"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            81..242
                     /locus_tag="AC1PIV_001881"
     CDS             81..242
                     /locus_tag="AC1PIV_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612859.1"
                     /translation="MKNIRLKLARVEKELEKWSNNKQFSSCSAIFLKNKNLQNSLPKV
                     RAYVTISKA"
     gene            357..1634
                     /locus_tag="AC1PIV_001882"
     CDS             357..1634
                     /locus_tag="AC1PIV_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015851 - nucleobase transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-xanthine permease family protein"
                     /protein_id="HIP6612860.1"
                     /translation="MSTKANLLFDVHEKPAPLQGILLSFQHVFAMFGATILVPLILGM
                     PVSVALFASGVGTLIYQVATQFKVPVYLGSSFAYISAMALAIKEMGGDVSAAQTGILF
                     VGLIYVLIAALVKVIGTKWIDTLLPPIVIGPMIIVIGLGLANSAVTSAGFVADGDWKN
                     VVVAIATFLIAAFVNTKGKGFAKIVPFLIAIIGGYVIALCLGLVDFTPVLEAAWFELP
                     GFYLPFETGAFKSYNFYFGPEMIAILPIAVVTVAEHIGDHTVLSQICGRQFLKDPGLS
                     RTLIGDGVATAVSAFIGGPANTTYGENTGVIGMTRIASVSVIRNAALIAIAFSFLGKF
                     TSLISTIPSAVLGGMSILLYGVIASNGLKVLIESRVDFGQVRNLIIASSMLVLGLGGA
                     VLNIGAITLSGTALSAIVGIILNLILPKAEKAE"
     gene            1838..2107
                     /gene="rpsO"
                     /locus_tag="AC1PIV_001883"
     CDS             1838..2107
                     /gene="rpsO"
                     /locus_tag="AC1PIV_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HIP6612861.1"
                     /translation="MAISKEKKNEIMAQYARHEGDTGSVEVQVAVLTWEINHLNDHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRRTDVNRYRELIHSLGLRR"
     gene            complement(2258..>3083)
                     /locus_tag="AC1PIV_001884"
     CDS             complement(2258..>3083)
                     /locus_tag="AC1PIV_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014917317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HIP6612862.1"
                     /translation="NRNILNHSIENLTPTENKLLDYIEENIHRIETMNIYQLADNAGV
                     STATISRISKKMGYSNFNKLKIEIAKSKYDDLLNAHFTPSDSIDDISTKLIHSITISN
                     QQTVSFLNLEELEAAVKLLQSASRIYLFGVGASGIVCSDFYYKLSRIGKTCIFAQDTH
                     IQMANIATAGNGDLAIGISYSGMTKEVVEPLRFAKENGVSTITITGTGKNQLADLADI
                     TFRIPRHEHELRVGAITSRSNSLFLTDLLYLALIQDHKQEITAILEQTKHLTEVIK"
BASE COUNT          847 a          609 c          651 g          976 t
ORIGIN      
        1 gaaatgtaag atatatattt caaaatagaa aatatagtgt gtaataaaat tataaaaatg
       61 cacaggagga tggctatggc atgaaaaata ttcgtttaaa gttagctcgt gtggaaaaag
      121 agttggaaaa atggagtaat aataagcagt tcagctcctg ctcagccatt tttctaaaaa
      181 ataaaaattt acaaaattcc ttgccaaaag taagggctta tgttacaata tcaaaagcgt
      241 aggtttttaa actcatcccg tgaggtgaga aagacaacag gataattcat taagggccta
      301 tgactatgta tatttagaaa gtctgggtct ttttgtgtac ccagaatggg agatttatga
      361 gtacaaaagc caatcttttg tttgatgtcc atgagaaacc agcaccgctt caagggattt
      421 tgttgagttt ccagcacgtg ttcgctatgt tcggagcgac aatcttggtg ccactgattc
      481 tcggtatgcc agtttccgtg gctctcttcg catcaggtgt cggaaccttg atttaccaag
      541 tagcgacaca gtttaaggtg ccggtttacc tgggatcttc cttcgcctac atctcagcta
      601 tggccctcgc cattaaggaa atgggcggcg atgtgtcagc tgcgcagaca ggtattctct
      661 ttgtcggttt gatttacgtc ttgattgctg cgcttgtcaa agttatcggg accaagtgga
      721 ttgataccct cttgccaccg attgttatcg gtcctatgat tatcgttatc ggtctgggtc
      781 ttgccaactc tgccgtgact tcggcaggct ttgtcgcaga cggtgactgg aaaaacgtcg
      841 ttgtggcgat cgcaaccttc ttgattgctg cttttgtcaa taccaaaggg aaaggcttcg
      901 ccaagattgt tcccttcttg attgccatca tcggtggtta cgtgattgca ctctgtcttg
      961 gtttggttga cttcacacct gttctggaag cagcttggtt tgaattacca ggtttctacc
     1021 taccatttga aacaggtgcc ttcaagtcgt acaatttcta cttcggtcca gaaatgattg
     1081 ctatcttacc aattgctgtt gtaacagtag ctgagcatat cggtgaccac accgttctca
     1141 gccaaatctg cggccgccag ttcttgaaag atccaggcct cagccgtacc ttgattggtg
     1201 acggtgtggc gactgccgta tctgccttta tcggtggacc tgctaacacg acttatggtg
     1261 aaaatacagg ggttatcggt atgactcgca tcgcatcagt atccgttatc cgtaatgcag
     1321 ccttgattgc cattgccttc tcattcttgg gtaaatttac atcccttatc tctactattc
     1381 caagtgccgt acttggaggc atgtctatct tgctttacgg ggttatcgcc tcaaacggtt
     1441 tgaaagtttt gattgagagc cgtgttgatt tcggtcaagt ccgtaacctg attattgcaa
     1501 gctcaatgct ggtattgggt cttggtggag cagttctcaa catcggtgcc atcacccttt
     1561 caggtacagc cctctcagcc attgtaggta ttatcctcaa tctcatcttg ccaaaagcag
     1621 aaaaggcaga gtaaatgtga tatacaagca gaaagtcagc aaaagctggc tttttttgaa
     1681 aatagcagag ctactcagct agttttcaaa tcagttgaca aaaaagacaa tccttgatag
     1741 aataaatgag gtccaaaagg acaaatctag ctttttcttg gttacaggtc gccaacctgt
     1801 cactcggatt aggctcaaaa acaaaggaga acatatcatg gcaatctcaa aagagaaaaa
     1861 aaatgaaatc atggcacaat atgctcgtca tgaaggcgac acaggttcag ttgaagttca
     1921 agtagcagta cttacttggg aaatcaacca ccttaacgac cacatcaaac aacacaaaaa
     1981 agaccacgca acttaccgtg gtttgatgaa aaaaatcggt cgccgtcgta acttgttggc
     2041 atacctacgc cgcacagacg ttaaccgtta ccgtgaattg attcactcac tcggactccg
     2101 tcgttaatta gcaggtatag aaacaaaaaa acacagcacc agtatcttgt atactgagct
     2161 gtgttttttg tttttttccc tattgtatga gttgcttcaa taaaagattc gatcgagctt
     2221 aggggatttg ctttttgtag tggatttatc aggtggtcta tttgattact tctgtaagat
     2281 gttttgtttg ttctaagata gctgtaatct cttgtttatg atcctggata agtgctaggt
     2341 aaagcaagtc ggttaggaaa agtgagttgc ttcgtgatgt aatagccccg actcgaagtt
     2401 catgctcatg tcgtgggatt ctaaatgtaa tatcggctaa atctgctaat tgattcttac
     2461 cagttccagt gatagttatc gttgaaactc cattttcttt tgcgaaacga agtggctcaa
     2521 cgacttcttt tgtcattccg ctataactaa ttccgattgc taagtcaccg tttccagcgg
     2581 ttgcaatatt agccatctga atatgtgtat cttgtgcaaa aatacatgtt ttacctattc
     2641 tactcagctt gtagtaaaag tcactgcaaa caatacctga tgccccaact ccaaataaat
     2701 aaattcgaga agcgctttgt aataatttta cggcggcttc taattcttcc aagtttagaa
     2761 aactgacggt ttgttgattt gaaattgtta ttgaatgaat taatttagta gaaatatcgt
     2821 caatcgaatc tgatggcgtg aagtgagcat tgagtaaatc atcatatttc gatttggcta
     2881 tttctatctt taacttatta aagttagaat agcccatttt tttactgatt cgactgattg
     2941 tagctgttga tactccggcg ttatcggcta attgatagat attcattgtt tcaatacgat
     3001 ggatgttctc ttcaatataa tccaataatt tgttttcggt aggggttaaa ttctctatcg
     3061 agtgatttaa aatgtttcta ttc
//
LOCUS       DBNFCO010000127         3043 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.129, whole genome shotgun sequence.
ACCESSION   DBNFCO010000127 DBNFCO010000000
VERSION     DBNFCO010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3043)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3043)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3043
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.129"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            30..404
                     /locus_tag="AC1PIV_001885"
     CDS             30..404
                     /locus_tag="AC1PIV_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HIP6612863.1"
                     /translation="MAWKFDNNIPIYIQISNTIKLQIVTNQLKSGDKLPTVRDLAEIA
                     GVNPNTVQRALSDLETEGFVYSVRTTGRFVTDNQELITQTRLHLAQKELENFVNNMLE
                     LGFRHDELTSQLDDYLKGVTYE"
     gene            397..1104
                     /locus_tag="AC1PIV_001886"
     CDS             397..1104
                     /locus_tag="AC1PIV_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIP6612864.1"
                     /translation="MSNAYTLVELQQVSKSYGGAVALNNVNLKLAAGKIIGLLGPNGS
                     GKTTMIKLINGLLQPEYGQVLINGRTPSPETKAIVSYLPDTTYLDEHMKVLEAVTFFE
                     DFYADFDKERALHLLQDLGIDLNSRMKHLSKGNKEKVQLILVMSRQAQLYVLDEPIGG
                     VDPAARDYILKTIVNNYSPTASVIISTHLISDVEQILDEVIFLHYGSVIRHGNVDDLR
                     IESGESIDELFRQDFKA"
     gene            1121..1903
                     /locus_tag="AC1PIV_001887"
     CDS             1121..1903
                     /locus_tag="AC1PIV_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIP6612865.1"
                     /translation="MFKKLLKYEFQSVGKWYLGIYIAAVVLSAVLGFWLQALALRTQA
                     GNTEPGGGEMVLLGTSFMTFGILIAALFLSTFVLVINRFRKNVYGRQGYLTMTLPVSS
                     HQIILSKLLASIVWYILAGITCLLSIGIILAVILAASEEAIMPEIQTFVQAIDWTILF
                     SQIVYYLIEITTGILLIYFSISVGQLFKDHRFLFAILTYIGILIVTGVFSTFFVLSNL
                     GTAYSTPFSLYPSPVLALVNIILAFAYYFGTHFIMTKKLNLQ"
     gene            complement(1947..2948)
                     /gene="add"
                     /locus_tag="AC1PIV_001888"
     CDS             complement(1947..2948)
                     /gene="add"
                     /locus_tag="AC1PIV_001888"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004000 - adenosine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0019239 - deaminase activity [Evidence
                     IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HIP6612866.1"
                     /translation="MLNVNELVKTELHCHLDGSLSLGVIRQLAQMAKITIPAEDEALR
                     KLVSVHGKVDSLMAYLKLFDFVRPLLQTATALELAAYDLVRQVASDKVIYIEVRFAPE
                     LSTDQDLTILEAVSAVLVGLNRGQEDFGVVAKLLVCGLKQTNTNQTKELFLAIADLAP
                     KGLVGFDFAGNEADYPTEELRDIIQFTQSLGYPMTFHAGECGCVTNVIQALELGIRRI
                     GHGTALTRNPEAIQAFVNSGATLEMCLTSNLQTGAADSIEYFPYRELVEAGANITINT
                     DNRTVSNTTLNREYQLFVEYFGTSKADFYRFNQNAIQASFASEEEKKVLLELLDQQY"
BASE COUNT          903 a          618 c          552 g          970 t
ORIGIN      
        1 cacggtgtca tcctagaaag gaaatgatta tggcttggaa atttgataat aacatcccca
       61 tctatattca aatcagcaat actattaaat tgcagattgt gactaatcaa ttaaaatctg
      121 gagataaact tcccactgtt cgtgacttag ctgaaattgc tggcgtcaat ccaaataccg
      181 ttcagcgcgc tttgtctgat ttagaaacag aaggatttgt ttactcggtt cgcacaacag
      241 gtcgttttgt aacagataat caagaattga ttacacaaac tcgcctacat ttagcccaaa
      301 aggaactgga gaacttcgtg aacaatatgt tagaattggg ctttagacac gatgaactca
      361 ctagccagtt agatgattat ttgaaaggag ttacttatga gtaacgcata tactttggtt
      421 gagctacagc aagtttcaaa atcttatggt ggagctgtcg ccctaaataa tgttaatttg
      481 aagttagctg ccggaaaaat cataggactt ttgggaccaa atggttcggg taaaacaacc
      541 atgattaaat tgatcaacgg cctgttgcag ccagaatatg gtcaagtatt gatcaatggt
      601 cgcacaccat cgccagaaac caaggcgatt gtatcttatc tcccagatac cacttatctt
      661 gatgaacata tgaaagtgct cgaagcagtt acattttttg aagattttta cgctgatttt
      721 gataaggagc gtgctctcca tcttttacaa gatttgggta ttgatttaaa cagtcgtatg
      781 aaacatctct ccaaggggaa taaggaaaaa gtccagctca ttctggtgat gagccgtcaa
      841 gcacagctgt atgttttaga tgagccaatt ggtggtgttg accctgccgc ccgagactac
      901 attttaaaaa ccatcgtcaa caactattct ccgactgcct ctgttattat ctctactcac
      961 ttaatttcag atgttgagca aattttggac gaggttattt tcctacacta cggaagcgtt
     1021 attcgccatg ggaatgtaga tgacttgcga attgaaagcg gagaatctat tgacgaactc
     1081 ttccgccaag attttaaggc ttagttagaa ggagattgct atgtttaaaa aattattgaa
     1141 atacgaattt caatccgtag gtaaatggta tttgggaatt tatattgcag ctgtggtcct
     1201 atcagcagta cttggttttt ggctacaagc gttggccctc cgtacacagg ctggaaatac
     1261 tgaacctggc ggtggagaga tggtcttatt gggaacatcc tttatgactt ttggtatttt
     1321 aattgccgca ctcttcttgt caacatttgt tctagtaatc aaccgtttta gaaaaaatgt
     1381 ttatggccga caaggttatc tcactatgac cctgccggta tctagccatc agattatctt
     1441 aagcaaacta cttgcctcta ttgtttggta tatcttggca ggtattactt gcttactttc
     1501 aattggaatc atccttgcag tcattctagc agcaagcgaa gaagctatta tgccagaaat
     1561 acaaactttt gttcaagcta tcgactggac aattctattc agtcagattg tctattattt
     1621 aattgaaatt accactggta tccttttgat ctacttctct atatctgtcg gtcaattatt
     1681 caaggatcat cgcttcctct ttgcaatctt gacttatatc ggcattctca tcgttactgg
     1741 agtatttagc actttctttg tcctaagtaa cctaggaaca gcttattcta caccattttc
     1801 tctctatcca agtccagtct tagcattagt caatattatc ctagcttttg cttactactt
     1861 tggaacccac ttcattatga caaagaaatt aaatctacag taaaaagctc tttactggtc
     1921 taatcgaccg gtatagagct tttttcttaa tactgttggt ctaggagttc caacaaaact
     1981 ttcttttctt cttcgctggc aaaacttgcc tgaatagcat tttgattgaa gcggtaaaaa
     2041 tcagctttgc tagtcccaaa atattctaca aataactgat attctctatt aagtgtagta
     2101 ttagaaacgg tacgattatc tgtgttgatt gtgatgtttg ctcctgcctc aactagctca
     2161 cgatatggaa aatattcaat cgaatcagct gcaccagttt gaagattcga tgttaggcac
     2221 atttcaagtg ttgctccgct attgacaaaa gcttggatag cttcaggatt gcgagtaagt
     2281 gctgtgccat gaccaatcct tctaatccca agttcaagag cttgaatcac attggtcaca
     2341 catccacatt ctccggcatg gaaagtcatg ggataaccta aagactgagt aaattgaata
     2401 atatcccgaa gttcttccgt aggatagtct gcttcatttc ctgcgaaatc aaatcccaca
     2461 agtccttttg gtgccaaatc agcaatagcc aaaaagagtt ccttcgtttg attcgtattc
     2521 gtttgcttta aaccacaaac cagaagttta gcaaccactc caaaatcttc ctgccccctg
     2581 tttagtccaa ctaaaactgc tgagaccgct tctaaaatag tcaagtcttg atccgtcgac
     2641 agttctggtg caaaacgaac ctcaatgtaa atgaccttat cacttgcaac ttgtcgtaca
     2701 agatcatagg ctgccaattc taaagctgtt gcagtttgta agagtgggcg aacaaaatca
     2761 aataacttta aataagccat taaactatca acttttccat gaacactaac taattttctt
     2821 aatgcttcat cttctgcagg aatagtgatt ttagccatct gtgccaattg tcgaatgact
     2881 ccgagggaca atgagccatc caaatgacaa tgcaattctg ttttgaccaa ttcatttaca
     2941 ttcaacacta ttaacacaac ctccgtctgg tatattgtta actatcatat catatttttg
     3001 aagaaaaaca agaattttac cataaaacct gaactttcat ttg
//
LOCUS       DBNFCO010000128         2927 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.130, whole genome shotgun sequence.
ACCESSION   DBNFCO010000128 DBNFCO010000000
VERSION     DBNFCO010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2927)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2927)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2927
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.130"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(<1..1572)
                     /locus_tag="AC1PIV_001889"
     CDS             complement(<1..1572)
                     /locus_tag="AC1PIV_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HIP6612867.1"
                     /translation="MKLTIFDKVQNKTSQFAIDELTYYLKAIFDFELGKTTVEEDANV
                     LLSKEYLDNNDTIGIEMKNGNAILTGNSDVSILIAVYRLLSEFGAVFTRPGRKHELIP
                     SLTITDWNEKELSIHETASYKHRGVCIEGADSYQNTKEFLDWLPKINMNSFFIQFENP
                     YSFLKRWYEHEFNPYADKEDFNTEIAQQMSDLLDEELSKRGLIHHRVGHGWTGEVLGY
                     SSKYGWESGLKLPEEKKPLVAELNGKRELFNTAPILTSLCFSNPDVGERMCELIVNYA
                     KERKDVDYLHVWLSDARNNICECEKCKQEIPSDQYVRILNQLDRKLSEEGLNTKICFL
                     LYHELLFAPKHEVLENPERFTMMFAPITRTFEMSYADVDYENDVPLPNEYSRNNIVLP
                     NSLEENLSYLFSWQKVFNGDSFVYDYPLGRAHYGDLGYMKISKVIFRDVVYLKKLGLN
                     GYISCLELRAGFPHNFPNFVMGQMLWNRNLEYDELKALYFSSLYGSEWKSVVTYLEKL
                     SDYSSCDYFNSIGDRQ"
     gene            complement(1577..2905)
                     /locus_tag="AC1PIV_001890"
     CDS             complement(1577..2905)
                     /locus_tag="AC1PIV_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012774924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HIP6612868.1"
                     /translation="MNGLMHFLEHKLAPFGTKVGNQRHLKAVRDGFMMAMPLVLVGSF
                     FLLLISWPDQASGGFSVVGFLEQIGLLGILNRLNQSTMAIISLIATFGIAYRLSESYE
                     TDGPSAGVIALSSFILLAPRFSTMVFNESGEQINQVFAGAIPFGSLNASALFVAIAVG
                     LVSAEIYRFFIQRGITIKMPKNVPDVVGKSFAALLPALTTLIFWACVFQGLEAAGVEG
                     GLGAVLGLIVGKPLGLIAGSLGGMVLVVLVNSLFWFTGVNGGQVLNAFVDPVWLQFTE
                     ANQLAAAAGEKLPHIITLPFKDLFVFMGGGGATVGLALCLLVFSKSRTFKSLGRISFI
                     PSLFNINTAILFSFPTVLNPIMMIPFILTPTVNAIITYFAMATGLVPMTTGVVLPWTM
                     PPILGGFLATGGSIQGAILQIILIGVSFIIYYPFFKVADNKNLELEESGE"
BASE COUNT          993 a          606 c          443 g          885 t
ORIGIN      
        1 ttggcgatca cctattgaat taaaataatc acatgaagag taatctgata atttttctaa
       61 gtaagttacg acacttttcc attcagaacc atataaggaa ctaaaataga gcgctttcaa
      121 ttcatcgtac tctaaatttc tgttccacaa catttgaccc atcacaaagt tgggaaagtt
      181 atgagggaaa ccagcgcgta gctccaggca actaatataa ccatttaaac ccaatttttt
      241 aagatatacg acatctctaa agattacttt actgatcttc atatatccta aatcaccata
      301 atgtgcccga ccaagtgggt aatcatatac aaaactatct ccattaaaca ctttttgcca
      361 actaaataaa tatgagagat tttcttcaag tgagttagga agaacaatat tatttcttga
      421 atactcattt ggaagcggaa catcgttttc atagtctaca tctgcataac tcatttcgaa
      481 agttctggta attggtgcaa acatcatagt gaaccgttca ggattctcta aaacttcatg
      541 ttttggtgca aaaagtaatt catgataaag taaaaaacaa atctttgtat taagcccctc
      601 ttcacttaat ttccgatcta attgatttaa tattcgtaca tattgatctg agggtatttc
      661 ttgtttacat ttttcacatt cacaaatatt gttccgtgca tcggataacc aaacatgtaa
      721 atagtctaca tctttccttt ccttagcata atttacaatc agttcacaca ttctttcacc
      781 aacatctgga ttggagaaac atagactagt tagtattggc gctgtgttga ataactcacg
      841 ttttccattt aattcggcga ctagcggttt cttttcttca ggtagtttta acccagattc
      901 ccatccgtac ttagatgaat atccaagtac ttcaccagtc caaccatggc caacacgatg
      961 atgtattaaa cctcgttttg ataattcttc atctaaaagg tcgctcattt gttgtgcaat
     1021 ttccgtattg aaatcttctt tatccgcata cggattaaat tcatgttcat accagcgctt
     1081 taaaaatgaa taaggattct caaactgaat aaaaaagcta ttcatattaa ttttgggtaa
     1141 ccaatccaaa aattcttttg tattctggta actatctgca ccttctatac atactcctcg
     1201 atgcttataa cttgcagtct catgaataga aagctctttc tcattccagt cagttatcgt
     1261 taatgagggg attaattcat gttttctacc cggtctagtg aatacagctc caaattcact
     1321 aagtaaacga tataccgcaa taaggattga gacatcagaa ttacctgtta atattgcatt
     1381 tccatttttc atttcaatcc caatcgtatc attattgtca agatattctt ttgacaaaag
     1441 aacattcgca tcttcctcaa cagttgtctt tcctaactca aaatcaaaaa tggctttcaa
     1501 gtaatatgta agttcatcta tagcaaattg agaagtctta ttctgtactt tatcaaaaat
     1561 cgtcaatttc atatgatcac tctcctgatt cttcaagctc taaattctta ttatcggcca
     1621 ctttgaaaaa tggataataa ataatgaatg agacacctat taaaataatt tgtaaaattg
     1681 ctccctgaat actgccgcca gtagcaagga accccccaag aattggaggc atcgtccaag
     1741 ggagaacaac cccagtagtc atcggaacta atccagttgc catagcaaaa taggtaatta
     1801 ttgcattaac tgtcggtgtt agaatgaacg gaatcatcat aataggattc aaaacagttg
     1861 gaaaactaaa cagaatggct gtattaatat taaagagaga aggaataaag gagattcgtc
     1921 ctaaactctt aaatgtacga cttttactaa agacaagtaa gcaaagcgct aatcctacag
     1981 tagcgccacc accgcccata aatacgaaca aatctttgaa aggcaaagta ataatatgtg
     2041 gtaatttttc tcccgcggcg gctgcaagtt gatttgcttc tgtaaactgt aaccaaaccg
     2101 gatcgacaaa agcatttaac acttgtccac cattaacacc agtaaaccag aaaagtgaat
     2161 ttacaagcac aacaagcacc attccaccga gacttcctgc aataagacca agtggtttac
     2221 ctacaattaa tcccaaaacc gctccaagtc caccttcaac accagcagct tctaatccct
     2281 ggaagacgca agcccagaaa attaatgttg ttaatgctgg aagcaatgcg gcaaatgact
     2341 tacccacaac gtctgggaca ttttttggca ttttaattgt aatacctctt tggataaaga
     2401 aacgataaat ttcagctgaa actaatccaa cagcaatagc aacaaataat gcacttgcgt
     2461 tcaaacttcc aaatggaatt gctccagcaa atacttgatt aatttgttca ccagattcgt
     2521 tgaaaaccat tgttgagaat cttggcgcaa gtaaaataaa agatgataaa gcaataacac
     2581 ctgcagaagg tccatctgtc tcatatgatt cggataatcg atatgcaata ccgaatgtag
     2641 ctatgagaga gataatcgcc attgttgatt gatttaaccg atttaaaatc cccaacaaac
     2701 caatttgctc taaaaagcct actactgaaa atcccccaga agcctgatcc ggccaactga
     2761 ttagcaatag gaagaacgag ccaactaata caagaggcat agccatcata aaaccgtcac
     2821 gaactgcttt caaatgacgt tgattcccta ccttagttcc aaaaggagct agtttatgtt
     2881 caagaaaatg cattaatcca ttcattttct tatcctccat taatttt
//
LOCUS       DBNFCO010000129         2906 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.131, whole genome shotgun sequence.
ACCESSION   DBNFCO010000129 DBNFCO010000000
VERSION     DBNFCO010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2906
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.131"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            <1..645
                     /locus_tag="AC1PIV_001891"
     CDS             <1..645
                     /locus_tag="AC1PIV_001891"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HIP6612869.1"
                     /translation="TTTHLSNPSAQRSYTVYIDPGHGGRDSGASYGGVHEKNLALSVS
                     NKLRENLLQYGINVLMTRTGDYDVDFKTERSRMTNASNADLFISIHFNATGAGVSNAT
                     GIETYWYQYNPEYQPKINKEMHNNPTRLAESEILANKVQESLIKETGAVNRGVRRETF
                     AVLRETAIPAILVELGFMDNPSELQVIKQDSYHTRLAKALAQGVMNWYGAVEGK"
     gene            723..1151
                     /locus_tag="AC1PIV_001892"
     CDS             723..1151
                     /locus_tag="AC1PIV_001892"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF013954.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HIP6612870.1"
                     /translation="MEQSSKANSILSSVMLSQAILESAWGTSYLATHGNNLFGIKADA
                     AWTGATIEIITNEYRDGEKKQEKHLFRKYNSWNESVADYAKFFTSTPWRIKNYQSFRE
                     ATDYQQAILALRQSGYATDPKYGEKLRSIIENYKLYLLDN"
     gene            complement(1211..>2906)
                     /locus_tag="AC1PIV_001893"
     CDS             complement(1211..>2906)
                     /locus_tag="AC1PIV_001893"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016772 - transferase activity,
                     transferring phosphorus-containing groups [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HIP6612871.1"
                     /translation="LWNNLIIIGVLYLILVFTTNLRFASLLILSASVFIGISNQLLID
                     SRGAPLLFYNLFQITDGLNVASSVAININNRMLQSMVFSYILLTFFFFIPKLYLPKLL
                     PSRTFYSSYDFKWPKRFSRILLGYITLITIVPMINKTVVSNANISLNYWRMYVTYGQF
                     GLPLSLASFYEDSKITKPEGYSVPKLNEVLEKYPPETEKQTIRPNIIFIQNESQSDFS
                     NLQGLNMEPNPLSNQHALTDNTIHGTLNVSVFGGGTANTEYEVLTSNPISLLSSNLFP
                     YQQIITQDRPSFATYLKNKNYDTVALHPQSGNNYNRNAVYPLLGFNKSYFLDSEPAIS
                     SLAPLTIDRGWPSDQFLFNGIKELYTQKGDQPLFSFVVTMQGHGGYPSTEEIYPREVS
                     INGSTSEYLAETEFLTSMKRTDEAFADLITFFSTYKEPTVIVMYGDHQPSLTQEFYAQ
                     FMDENNPAAKYSTPLVIWSNFDIRERESTTISPNYLVPYLMDILSESDYALPRSPYQQ
                     FLSDMQIEAPIITSWGNIDNNGQQIEDLSTLPLYQTYLQLEYNSAIDKQPLTDLYE"
BASE COUNT          929 a          466 c          625 g          886 t
ORIGIN      
        1 acaacgactc atttatcaaa tccgtcggca cagcgatcct acacagtcta tattgaccca
       61 gggcacggag ggcgagactc gggtgcttct tacggtggcg tacatgaaaa aaatcttgca
      121 ttgtctgttt caaataagtt gcgtgaaaat ctcttgcaat atggaatcaa tgttttgatg
      181 acccgtacag gtgattatga tgtagacttc aaaacagaga ggtcacgaat gacgaatgca
      241 agcaacgcag acttatttat tagtatccat tttaatgcga cgggtgcagg agtttcgaat
      301 gcgactggta tcgaaacata ttggtatcaa tataatccag aataccaacc taaaattaat
      361 aaagaaatgc ataataaccc tactcgttta gctgaaagtg agattttagc caacaaggtc
      421 caggagagtt taattaaaga aacaggtgca gttaaccgtg gtgtaagaag agaaactttt
      481 gcagtccttc gcgagacagc aattcctgcc attctagtgg agctaggatt tatggataat
      541 ccttcggagt tgcaagttat caaacaagat tcttaccaca ctcgccttgc gaaagcattg
      601 gcacaaggtg taatgaattg gtatggtgct gttgagggaa agtagaaatt gcaggtacag
      661 gtattgaaac aggaaaactt tctaatgatc aaaaaagttt catagccaat ctagtacctg
      721 caattgaaca aagttcaaaa gctaattcta tcctttcgag cgtcatgtta tctcaagcca
      781 tcctcgaaag tgcatgggga acgtcatact tggcgactca tgggaataat ctttttggca
      841 tcaaagcgga tgctgcgtgg acaggtgcta caattgaaat cattaccaat gaataccgtg
      901 atggtgagaa gaagcaagaa aagcacttgt ttagaaaata taattcatgg aatgaaagtg
      961 tagcagacta tgctaagttc tttacctcta ctccgtggag aataaaaaat taccagagtt
     1021 tcagagaggc aactgattat caacaagcga ttcttgcgct aagacaatca ggatatgcta
     1081 ctgatccgaa atatggtgaa aaattacgat caattatcga gaattacaag ctttatcttt
     1141 tagataatta agttttttgg gtgattgatg ataaaatagc cttgctcaaa accgagcaag
     1201 gctattttta tcactcatat aaatctgtta aaggttgttt gtcaatggca ctattgtatt
     1261 ctagttgtaa gtaggtttgg taaagtggta gggttgatag gtcttcaatt tgttggccat
     1321 tattatcgat atttccccag ctagtaatga taggtgcttc gatttgcata tcactcaaaa
     1381 attgttggta aggtgatcga ggaagggcat agtcggattc ggataaaata tccatcaaat
     1441 atggaacgag atagtttggg ctgattgttg tagattcgcg ctccctaata tcaaaattcg
     1501 accaaatcac taaaggggta gaatatttag cggcaggatt attttcatcc ataaattgtg
     1561 cgtaaaattc ctgagtcaaa ctaggttggt gatcgccgta catgacgatg actgttggct
     1621 ctttgtaagt actaaagaaa gtaattaaat ctgcaaatgc ttcatctgtt cttttcatgc
     1681 tggtcaaaaa ttctgtttca gctaagtatt cagatgttga accattaatg ctgacttcgc
     1741 gaggataaat ttcttccgta cttggatagc ctccatgtcc ttgcatggta acaacaaagc
     1801 taaatagagg ctggtctcct ttttgggtat aaagttcttt tattccgttg aacaagaatt
     1861 gatcagatgg ccagccacga tcgattgtta gtggtgctaa gctactaata gcaggttccg
     1921 aatctaaaaa ataagattta ttaaacccca gtagaggata cactgcattg cggttgtaat
     1981 tatttccgga ttgaggatgt agagctacag tgtcgtaatt tttatttttt agataagttg
     2041 cgaaacttgg acggtcttgt gtgataatct gctgatatgg gaataaatta gaagataata
     2101 aactgattgg gttacttgtc agcacttcat actcggtatt tgcagtacca ccgccaaaga
     2161 ctgagacatt gagggtgcca tgaatagtat tgtctgttaa agcatgttgg tttgatagcg
     2221 gattaggctc catatttaag ccctgtaagt ttgaaaaatc actctgtgat tcattctgta
     2281 taaagataat attaggtctg attgtttgtt tttctgtttc aggagggtac ttctcaagaa
     2341 cttcattaag tttggggact gagtatcctt caggcttagt tattttacta tcttcataga
     2401 aagaggcgag tgagagtggt agcccaaatt gaccataggt gacgtacatt ctccagtagt
     2461 ttaatgatat atttgcatta gagacgacag ttttattaat cattggaacg attgttatta
     2521 aagttatata gcccagtaaa attctgctga aacgtttcgg ccatttgaaa tcataactag
     2581 aataaaacgt tctagaaggt agaagttttg gtaaatataa tttggggata aagaaaaaga
     2641 aggtcaataa gatataagaa aataccatac tttgtagcat tcgattgttg atattaattg
     2701 ctacgctaga agctacattt aatccgtctg tgatttgaaa aagattataa aataatagag
     2761 gagcaccacg gctgtcaatc aaaagttggt tacttatacc aataaatact gaagcggata
     2821 gaattaatag gctggcaaat cgtaagttag ttgtaaagac cagtattagg tagaggactc
     2881 cgataatgat tagattgttc caaaga
//
LOCUS       DBNFCO010000130         2792 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.132, whole genome shotgun sequence.
ACCESSION   DBNFCO010000130 DBNFCO010000000
VERSION     DBNFCO010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2792)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2792)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2792
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.132"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            <1..878
                     /locus_tag="AC1PIV_001894"
     CDS             <1..878
                     /locus_tag="AC1PIV_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF2142 domain-containing protein"
                     /protein_id="HIP6612872.1"
                     /translation="IKYGKMTLFFVSLLPMMIQQAGSLSYDVVNYLAVVAFFVFYVNL
                     LVDKVLTTRKFINLILLSLLLYLTKANNILLLALLFFVDFEFEGVLSKFNSILKWIQK
                     RRLPILILGFGLVLLVSYLFLHNRGGVVHFVKVMINSLFINNRNDHLNGILTVGIFGY
                     FGWFVTQLPLWLIFIDIFIFTLLLFNDGNLKISKTEGLASLFVLPVQVAIIVAGMYFA
                     WTPTAIGPNAMISQGAQGRYFTPFLVYLFPACLMLKEQVSVSVKQKYLIRLLTGTVVI
                     NFIMYLFLIVDYYWV"
     gene            901..1890
                     /locus_tag="AC1PIV_001895"
     CDS             901..1890
                     /locus_tag="AC1PIV_001895"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HIP6612873.1"
                     /translation="MNILFTLNDAFVPQVAACMGSIMRTLDEDDTCHFYLFSDGISQQ
                     NKENLHQFVTDGGNKLTIVELENLESYFDFEVDTNGWASVVLARLLVDKLLPEEVDRI
                     IYLDGDTLVLENIRELWEVDLEGKVLGMCPEPTASSERREGLNLGTYTYHNAGVLLID
                     LKRWRSKSIGTIIFDYYKEKNGELFANDQDALNGALKEEIKTLSITYNYFNIFDVYPY
                     RTLEKLSRPSTFISKEEFVKIRKQPRIVHFLGEERPWRIGNKHRFREDYVSALNQTPW
                     RGTQFESGWQFYFFCFNLFNMVMKPFPMLRYKIITVLIPVFMKYRKIRLQKGV"
     gene            1893..>2792
                     /locus_tag="AC1PIV_001896"
     CDS             1893..>2792
                     /locus_tag="AC1PIV_001896"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HIP6612874.1"
                     /translation="MKFSVIIPAYNVADYLEECVYSVLNQTYEEFEILLVDDGSTDGK
                     TSNICDKLAAKDDRVKVFHQTNGGLSAARNTGIKNASGDYILFLDGDDFWTDICFLDE
                     VNREIISHDEVIDAVIYPFSYFYGKDDVAVRNFSKKLPFHQVITDTRLLVETGALITP
                     AWNKCVRRDKFTSALNFLSGYLYEDGIWCANLLKELNVFIVVDNTQCMYRQNRQGSIT
                     NNVTLRHVEHAFRGIEENLKNFKQLSNEKQEALLIYLSNSYISILPFVFPYLNNFDIK
                     MFVKKFRYLLKYSQKVELVSFRIS"
BASE COUNT          884 a          374 c          554 g          980 t
ORIGIN      
        1 aaataaagta tgggaagatg accctgtttt ttgtctcact tttacctatg atgattcagc
       61 aggctggctc actgtcttat gatgtggtga actatctggc tgttgttgca ttttttgttt
      121 tttatgttaa cttattggta gacaaggtac tgaccaccag gaaatttatt aacttaatat
      181 tactatcctt gctactatat ctaacaaaag caaataatat tttacttttg gcactattgt
      241 tttttgttga ttttgaattt gaaggcgtct tatctaagtt taattcgatt ttaaaatgga
      301 ttcaaaagag aagattacca attcttattt tagggtttgg actagtttta cttgttagct
      361 atctattcct acataataga ggtggtgtcg tgcactttgt gaaagtgatg ataaacagtt
      421 tatttatcaa taatagaaat gatcatctta atggtatttt aacggttggt atttttggtt
      481 attttggctg gtttgtcact caactacctc tctggttaat tttcatagat attttcattt
      541 ttacgttatt attatttaat gatggaaatt taaagataag taaaacagaa ggtcttgcgt
      601 cgttatttgt actccctgtt caggtagcta tcattgtagc gggcatgtat tttgcctgga
      661 caccgacagc tattggacca aatgcaatga tttctcaagg ggcacaagga agatacttta
      721 ctccgttttt agtctatcta tttccggcat gtttaatgtt aaaagagcag gtaagtgtat
      781 cggtaaaaca gaagtatttg atacggttgc tcactggcac agtagtcatt aactttatca
      841 tgtatctatt tttgatagtg gattattatt gggtgtaaga agatagtgga agagggaaac
      901 gtgaatatat tatttacatt gaatgatgct tttgttccgc aagttgcagc ttgtatgggc
      961 tcaatcatgc gaacattaga cgaagacgat acatgccatt tttatctttt ctcagatggt
     1021 ataagtcaac agaataaaga aaaccttcat caatttgtta ccgacggagg aaataaattg
     1081 acaatcgttg aattggaaaa cttggaatca tattttgatt ttgaagttga cacaaatggt
     1141 tgggcttcgg ttgtacttgc aagattactt gtagataaat tactgcccga agaagttgat
     1201 agaatcatct atttagatgg agatacttta gttttagaaa atattcggga gctatgggaa
     1261 gtagatttgg aggggaaagt ccttggaatg tgcccagaac cgacagcttc atctgagaga
     1321 agagaaggct taaatttggg tacgtataca tatcataatg cgggagttct tctaatcgat
     1381 ttgaaacggt ggcgttcaaa aagtatagga acaattattt ttgattatta taaagaaaaa
     1441 aatggagagc tttttgctaa tgatcaagat gcactgaatg gagcattgaa agaagagata
     1501 aaaacactct caatcactta taattatttt aatatttttg atgtttatcc atatcgtacg
     1561 ttggaaaaat taagtaggcc ttcaacgttt atttcaaaag aagaatttgt aaaaattcgt
     1621 aagcaaccac gtattgttca ttttttaggt gaagaacgtc catggagaat cggaaataaa
     1681 catcgattta gagaggacta tgtttctgca ttaaatcaga cgccatggag aggtactcaa
     1741 tttgagagtg gttggcagtt ttactttttc tgttttaatc tttttaacat ggttatgaag
     1801 ccttttccaa tgttgcgtta taaaattatt acagtcttaa ttcctgtatt catgaaatat
     1861 aggaaaatta gattacaaaa aggagtctag gtgtgaagtt ttccgttatt atcccagcgt
     1921 acaatgttgc tgattatctg gaagaatgtg tgtatagtgt actgaatcag acttatgaag
     1981 agtttgaaat attgttggta gatgacggtt ctacagatgg taaaacctcc aatatatgcg
     2041 ataaattagc agctaaagat gatagggtga aggtatttca tcaaactaat gggggattat
     2101 ctgcagccag aaatacaggg ataaagaatg ctagtggtga ctatatttta tttctggatg
     2161 gagatgactt ttggaccgat atatgctttt tagatgaagt taatagagaa ataatttcac
     2221 atgatgaagt tattgatgca gttatctatc cattttccta cttttacggt aaggatgatg
     2281 tagcagttcg aaatttttct aaaaaattac cgtttcatca ggttattaca gatacgcgct
     2341 tactcgttga aacaggagcc ctaatcaccc ctgcttggaa taagtgtgtc agaagagata
     2401 aatttacctc tgctcttaat ttcttgagtg gatatttata tgaagatggt atttggtgtg
     2461 caaatctctt gaaagagttg aatgtattta ttgttgtaga taatacacaa tgcatgtatc
     2521 gtcagaaccg acaaggaagt attacaaata atgtcacgct tcgacatgta gaacatgcct
     2581 ttagaggaat tgaagaaaat ttaaagaatt ttaaacaact atcgaatgag aaacaagaag
     2641 cacttttgat ttatttatca aattcttata tttccatctt gccatttgta tttccatatc
     2701 tgaataattt tgatataaaa atgtttgtga aaaaatttag atatttgcta aaatattcac
     2761 agaaggtaga acttgtttcg tttagaatct ca
//
LOCUS       DBNFCO010000131         2682 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.133, whole genome shotgun sequence.
ACCESSION   DBNFCO010000131 DBNFCO010000000
VERSION     DBNFCO010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2682
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.133"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            <1..269
                     /locus_tag="AC1PIV_001897"
     CDS             <1..269
                     /locus_tag="AC1PIV_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HIP6612875.1"
                     /translation="NFINTLEENVAKNNGIQRDAWRQLGYHREYVVKLANALHLMASG
                     DHLDGQIRWKDFLDYIRNHEPDFQQYLDVYRIIEVAKNYAGFKL"
     gene            389..>2682
                     /locus_tag="AC1PIV_001898"
     CDS             389..>2682
                     /locus_tag="AC1PIV_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="InlB B-repeat-containing protein"
                     /protein_id="HIP6612876.1"
                     /translation="MNKKIFLKSAIILLSVTCLINAIKALDSSGVSSSTGEIVNQDRI
                     YNITLKVKTDGVYNDLGGNVISENNVLSGISGTKINLKVSTNSGYRFVGYQSFLESGN
                     STDGLLPIENDSFEISDKTGNVTVVAMFEKIPIDETIYFSDEFSTENINNYLLSENLI
                     GKIAVSNGKLNIHAPGVSSIKPILSRQIDESSTLGYEIQFSIQQIGEVKQWNTFRVVF
                     KENSDGSVYALEFTGKAVSIKKLSSIDAPNQTGEKYAETGHNLGSEEHRIRLVVRGDT
                     VTVSDNEIPLLSYSSPENWEGATASIVFTPISNRSVSLDDIIIRQTRALRSLLVVSRI
                     DGQEVTDIQPGSIRGNTSQVFVGDSLPLEVIEKPGYQFIGFKDEFGNVVDLSTFSVPN
                     DESDLVIYADFQTAEVVNRETKTFYIDSIEGNDTNSGESETNAWKTLEQLRKNTLIAG
                     DRVLLKRGSRFVGEDAALTFKGSGLEDAPILISSYGEGELPLLEAQGKIESVIKLYNQ
                     EYITIENLEITNLDPNFSTSFELNSNNNRSKILRGVHVIAEDYGVVHDIVLRNMYLHD
                     INGNLNSKWNGGIFFDVYGTTVPTKYDGILIENNYLERVDRSGIKLVGSTWANQNLKN
                     NKNIPLNWYPSTNVVVRGNRIEKAGGDSITVRDTDGALIEYNISADARYQDTGYNAGI
                     WPFQASNTVIQYNESFRTHGVQDGQGLDLDHVSNNSVMQYNYSHDNEGGFMLIMNWYE
                     QTSPTVRYNISQNDKDKIFELARGG"
BASE COUNT          928 a          346 c          551 g          857 t
ORIGIN      
        1 ttaattttat taataccttg gaagagaatg ttgctaaaaa taacggaatt caacgtgatg
       61 cttggcgaca attaggttat caccgggaat atgttgtcaa attggctaat gcccttcatc
      121 ttatggcctc tggagaccat cttgatggac aaatccgctg gaaagatttt ttggattata
      181 ttagaaacca tgaacctgat tttcaacagt atcttgatgt ctatcgtatt attgaagttg
      241 ctaagaatta tgctggattc aaattgtagt actgagttgt agaaaaaagc caattcacaa
      301 tttattttgc gaattggctt gaagtctaat atagatagaa tattgaattt atttgatgtt
      361 aattgatatt tatttttgag aggattttat gaataaaaaa atttttttaa aatcagcgat
      421 tattttgctc tctgtcacat gtctaattaa tgcgattaaa gctttagata gtagtggtgt
      481 gtcatcgagt acaggtgaaa tagtaaatca agatcgcata tacaacataa ctttgaaagt
      541 gaaaacagat ggggtttata atgatctggg ggggaatgtt atttcggaaa ataatgtatt
      601 gtcaggaatt agtggtacaa aaataaattt gaaggttagt acaaattcag gatatcgttt
      661 tgtagggtat cagtcatttt tagaaagtgg aaatagtaca gatgggttac taccaatcga
      721 aaatgatagt tttgaaatct cggataaaac gggtaatgta acggttgttg cgatgtttga
      781 gaagattcct attgatgaga caatttattt ttcggatgaa ttctcaactg aaaatattaa
      841 taattacttg ttatctgaaa atctaattgg aaaaattgcg gtaagtaatg gaaaattgaa
      901 cattcatgct cccggggtat catcgataaa accaattctt tcaagacaga ttgatgaaag
      961 ttcaacattg gggtatgaaa ttcaattttc catacaacaa attggtgaag taaagcagtg
     1021 gaatactttt agagtagtat ttaaagaaaa tagcgatgga tcagtttatg ctctagaatt
     1081 tactggaaaa gctgtatcta taaaaaaact ttcaagtatt gatgcaccta atcaaactgg
     1141 tgaaaaatac gctgaaacag gccacaatct aggaagtgaa gaacacagaa taagacttgt
     1201 agtaagaggg gatacagtaa ctgttagtga taatgaaatt ccgttattaa gttatagcag
     1261 tcctgaaaat tgggaaggtg caacagcatc cattgttttt acaccgattt caaatagaag
     1321 tgtatcttta gacgatatca ttattcgaca aacacgtgct ttaagatctt tactagttgt
     1381 gtctcgtata gatggtcagg aagttacaga tattcaaccc ggatcaatca gagggaatac
     1441 aagtcaagtt tttgttggag attcacttcc tctggaggtc attgaaaaac ctggatatca
     1501 atttattggt tttaaagatg aatttggaaa tgtggtcgat ttatctactt tcagtgttcc
     1561 taatgatgag tcggatttgg ttatttatgc agactttcag acagctgaag tagtgaatcg
     1621 tgagacaaag actttttata ttgatagtat agaaggaaat gatactaata gtggagaaag
     1681 tgagactaat gcatggaaaa cactcgaaca attgcggaaa aacacactaa ttgctggtga
     1741 tagagtgcta ttaaaacgtg gaagtcgttt tgttggagaa gatgcggcat taacttttaa
     1801 aggttcaggt cttgaagatg cgcctatcct aatttcatct tatggtgagg gagagctgcc
     1861 tttgcttgaa gcacagggca aaattgaaag tgtaattaag ttatataatc aagaatatat
     1921 tacaattgaa aatctagaga ttacaaactt agatccgaac ttttcaacga gttttgaatt
     1981 aaattcaaat aataaccgtt caaaaatact aagaggtgtt catgttatag ctgaagatta
     2041 tggggtagtt catgatatcg ttcttcgaaa tatgtatcta catgatatta atggtaattt
     2101 gaattcaaaa tggaatggag gtattttctt tgatgtttat ggaacaacag ttccaaccaa
     2161 atatgatggc atacttattg aaaataatta tttagaaaga gttgataggt cagggattaa
     2221 attggtcggg tccacatggg caaaccaaaa tctaaaaaac aacaaaaaca ttccattaaa
     2281 ttggtatcca tcaacaaacg tagttgttcg tggcaatcgt atcgaaaagg ctggtggtga
     2341 ttctataaca gttagagata cagatggtgc tttaattgaa tacaatatct cggctgatgc
     2401 cagataccaa gatacaggtt ataacgctgg aatttggcca tttcaagctt caaatactgt
     2461 tattcaatat aatgaatcat ttagaaccca tggtgttcag gatgggcaag gtttagatct
     2521 agaccatgtt tcaaataatt cagtaatgca atataattac agtcatgata atgaaggtgg
     2581 tttcatgttg attatgaatt ggtacgagca aacatctcca acagtccgtt ataatattag
     2641 tcagaatgat aaagataaaa tttttgaatt ggctagaggg gg
//
LOCUS       DBNFCO010000132         2551 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.134, whole genome shotgun sequence.
ACCESSION   DBNFCO010000132 DBNFCO010000000
VERSION     DBNFCO010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2551)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2551)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2551
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.134"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            <1..>2551
                     /locus_tag="AC1PIV_001899"
     CDS             <1..>2551
                     /locus_tag="AC1PIV_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012774973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612877.1"
                     /translation="FYSYQLELTHDKTGEKNALDLDLKKIFAMIVYKNIFPKDFSELQ
                     NNQGFLYSLFNEKEVRRSEKLTKIDSEKLHLENKLRKIQSEHIQDEIELYGTIFKIPN
                     GRKVVSVNDKFQDEFTSYHDFISEMLVEGSRIISYVDFDDAYRNVGIKTENMDSIFPE
                     KDSPEFKERLDTVRSRNNSKELQQKIASLNQKRSFVEKQLIADIYTNQEIHEFAKSRE
                     EFIDIEKNQQFDIIYFLLKNSYIDETYPDYLTYFYGNVLTKNDKEFLRNISSGRGAGF
                     DFRLVNISNIYHHLQLKDFRNEEVLNFDLIEYMLKNLELQSREENLSAILLQEDNLDF
                     LVELAKKLYDSKSEKYNLEQFGQLMEFWLSTNPQRFIDYMKSTKVEYQAPLKNKFIRA
                     LMNQVNLDSVDNEIKALVARYINENNDLISPNEDFTSFFKTNLKAINLKFTHFREPDD
                     DAPRTTTFLELIDFIFGNSLYEINKENLRFFMRWFKGSTDWSEEDFKHKNFELLHTND
                     NYSPLLEYSRLKITDYVYAYLEICEGTILDNSEYIVELLQRNEVYESGFNLGTLEEER
                     QIDRILQFLPDNSINFNSDDFRQLVEEDILEEGNYLTLLSLLVQTSKAVVDTDIILSY
                     FTENQNYDNSLINFINNARDLKFEEDIFNLLEKEEQRNFFTKTVECMELDDTKYELIL
                     STLGWHYTDTFNKSGIESSKLRILIDLEIIQFNSKNIEFFRDNYPEDTLYLIKKHLSE
                     YLDTKSKIYKEDELLALLDDDIISDDEKTNIADHILKISIKNKQYSEKLTAHILENQF
                     DEEDLSYIISSQFFDNQSLSLKELVKQIAIENLDTIAEEFYAQISNNLMRKL"
BASE COUNT          945 a          320 c          467 g          819 t
ORIGIN      
        1 attttattct tatcagcttg aattgacaca tgacaagacg ggtgagaaaa atgcattgga
       61 tcttgatttg aaaaaaatat ttgcaatgat tgtctacaaa aatattttcc cgaaagactt
      121 ttctgagttg cagaataatc aaggttttct atattcattg tttaatgaga aagaagttag
      181 aagaagtgaa aaacttacga agattgatag tgaaaaactg catttagaga ataaactgag
      241 aaagattcag agtgagcaca ttcaagatga aattgaactc tatggaacaa tttttaaaat
      301 tccaaatggg agaaaggttg tcagtgtcaa tgacaaattt caagatgagt ttacttctta
      361 tcatgatttt atttctgaaa tgctggtgga aggaagtcgt atcatctcct atgtggattt
      421 tgatgatgct taccgtaatg taggtattaa aacagaaaat atggattcaa tttttccaga
      481 gaaagattct ccagagttta aggaacgcct tgatactgta agaagtcgca ataatagtaa
      541 agagttgcaa caaaaaattg cttcattaaa tcaaaaacgg agctttgttg aaaaacaatt
      601 gattgcggac atctatacta atcaagaaat acatgaattt gctaagagta gagaagaatt
      661 tattgatata gaaaaaaatc agcaatttga tattatttac ttcttattga aaaactctta
      721 tatagatgaa acctatccag attatttgac ctatttttat ggcaatgtct taactaagaa
      781 tgataaagaa tttttgagaa atatttccag tggaagaggt gcaggttttg atttcagact
      841 ggtaaatatt tcaaatatct atcatcattt gcaattaaag gactttagaa atgaagaagt
      901 tttaaatttt gacttgattg aatacatgct taaaaatttg gagttgcaga gtcgagaaga
      961 aaacttgagt gctatcttat tacaagaaga taacttggat tttttggttg aactggcaaa
     1021 gaaattgtat gatagtaagt ctgaaaaata taacttggaa cagtttgggc agttgatgga
     1081 gttttggcta tctactaatc cacaaagatt tattgactat atgaagtcta cgaaggtgga
     1141 gtatcaagct ccactaaaga ataagttcat tcgagctttg atgaatcagg tgaacttaga
     1201 tagtgttgat aatgaaataa aggcgttagt agctcgttat atcaatgaaa ataatgattt
     1261 aatttcacca aatgaagatt ttacatcatt tttcaaaaca aaccttaagg caatcaatct
     1321 taaattcact cattttagag agcctgatga tgatgctccc agaactacga ccttcttgga
     1381 gcttatcgac tttatctttg gcaatagttt gtatgagata aataaagaaa atttaagatt
     1441 ttttatgcgg tggtttaagg gaagtactga ctggtcagag gaagacttca agcacaagaa
     1501 ttttgaactg cttcatacaa atgataatta ttcaccgctg ctagagtata gtagattgaa
     1561 gataacagac tatgtctatg catatttaga gatttgtgag gggactattt tagataactc
     1621 ggaatatatt gtagaactac ttcaaagaaa cgaagtttac gagtctggat ttaatttggg
     1681 aacactggag gaagaacgcc aaattgatag aattttacag ttccttccgg ataatagtat
     1741 taatttcaat agcgatgatt tccgtcaact tgtagaagag gatattcttg aagaggggaa
     1801 ttatcttacc ttgctaagtt tactagttca aacttctaaa gccgtagtgg atactgatat
     1861 tatcttatct tattttaccg agaatcagaa ttatgataat agtcttatca actttatcaa
     1921 taatgcaaga gatttaaaat ttgaagagga tatatttaac ttacttgaga aagaagaaca
     1981 aagaaacttt ttcaccaaaa ctgttgagtg tatggagtta gatgacacca aatatgaact
     2041 catacttagc acacttggtt ggcactatac cgatacattt aataaaagtg gaatagagtc
     2101 aagtaagctt agaatattaa ttgatttgga aattatacag tttaactcta agaacattga
     2161 atttttcaga gataattatc cagaggatac actataccta atcaagaaac acttatcgga
     2221 atatctagat actaaaagta aaatatataa ggaagatgag ttgttagcat tacttgatga
     2281 tgacattatt tcggatgatg agaaaactaa cattgcagac catattttaa aaatcagtat
     2341 aaaaaataaa cagtattcag aaaaattgac tgctcatatt ttggaaaatc agtttgatga
     2401 agaggatttg agttatatca tcagtagtca attctttgac aaccagtcac tgagtttgaa
     2461 agagctagtt aaacaaattg caattgaaaa tcttgatact atagctgaag aattttatgc
     2521 ccaaattagt aataatttaa tgagaaagct a
//
LOCUS       DBNFCO010000133         2377 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.135, whole genome shotgun sequence.
ACCESSION   DBNFCO010000133 DBNFCO010000000
VERSION     DBNFCO010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2377)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2377)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2377
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.135"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(144..1004)
                     /gene="thrB"
                     /locus_tag="AC1PIV_001900"
     CDS             complement(144..1004)
                     /gene="thrB"
                     /locus_tag="AC1PIV_001900"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004413 - homoserine kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HIP6612878.1"
                     /translation="MKIIIPATSANIGPGFDSVGVALSKYLTIEVFEETDEWVIEHNL
                     EHVPSDKNNLLIKTALKIEKGLQPHRIRMISDIPLARGLGSSSSVIVAGIELANQLAG
                     LNMTADEKLLKATEIEGHPDNVAPAIFGNLVISSYVNKRVQAVVTEFPEASFVAFIPN
                     YPLRTVESRGVLPSQMGYKKAVAASAIANVAVASLMAGDLEKAGKAIQSDMFHEPFRQ
                     LLVKEFCPIKQTAQELGAYATYLSGAGPTVMVLAPKDREDAIVLALEELNLDGTVHRL
                     QVDTKGIAIV"
     gene            complement(1008..2294)
                     /locus_tag="AC1PIV_001901"
     CDS             complement(1008..2294)
                     /locus_tag="AC1PIV_001901"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019782768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004412 - homoserine dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HIP6612879.1"
                     /translation="MVVKIGLLGFGTVASGVPFLLEENQEKIEKAAHDSIEVAKVLVK
                     DEAEKDRLLAAGHDYHFVTNIDDILADEDIAIVVELMGRIEPAKTFITHALEAGKHIV
                     TANKDLLAVHGSELRALAEEKGLALYYEAAVAGGIPILRTLVNSLAADKVTRILGVLN
                     GTSNFMLTKMIDEGWTYEKALQTAQELGYAESDPTNDVEGIDAAYKAVILSQFAFGMT
                     VDFEHVAHKGISNITPEDVAVAQELGYVIKLVGDIQETTSGIAAEVSPTFLPKNHPLA
                     SVNGVMNAVFVESIGIGQSMYYGPGAGQKPTATSVMADIIRIVRRLKDNTIGKAFNEY
                     SRPLQLAAPSDVKSEYYFSIDAPDKNGKMLRLAEIFNSEEISFKQILQQAADGETARL
                     VIVTHEMSKTQLENVTDKLSKETDFTVLNTFKVLGE"
BASE COUNT          678 a          544 c          430 g          725 t
ORIGIN      
        1 agccaaatta atttgcccca atattttgaa atggagaatg gaatgcacaa aaaaaaggag
       61 ttccctttct accgcttaca gtagcgatgg cgaactccaa taaataaaca tgtttagttt
      121 tgcaaatgac agattctcac tatctataca atagcaatcc ctttggtatc tacttgaagg
      181 cggtggacag ttccgtctag atttagttcc tctaatgcta gaacaatagc gtcctcccta
      241 tctttgggcg ctaataccat cactgttgga ccggcacctg ataagtaggt tgcataggct
      301 cccaactcct gtgcagtttg cttgattgga caaaactcct taacaagtag ctgacgaaac
      361 ggttcatgga acatgtctga ctgaattgct ttcccagctt tttccagatc acctgccatc
      421 aaactggcaa cagcaacgtt tgcaatggca ctagcagcca ctgctttctt gtaccccatc
      481 tgagaaggca gtacacctcg gctttcaacc gtacgcagtg ggtagtttgg aataaaggca
      541 acaaaacttg cttctgggaa ttctgttaca actgcctgta ctctcttatt aacatagcta
      601 gagatgacta aattaccgaa aatcgctggg gctacattat caggatgtcc ttcaatttct
      661 gtagctttga gcaatttttc atccgctgtc atattcaaac ctgctaattg attagccaat
      721 tcgataccag ctacgataac ggaactggat gaacccaaac cacgtgccaa gggaatatca
      781 ctaatcattc tgatacgatg cggctgcaat cctttttcaa tctttaaagc tgtcttgatc
      841 aaaagattgt tcttgtctga tggaacatgt tcaagattgt gctcaatcac ccattcatca
      901 gtctcttcaa atacttcaat cgttagatat ttcgaaaggg caacacctac tgaatcaaat
      961 cctggaccga tattagctga agttgctgga ataataattt tcattgctta ttctcccagt
     1021 actttaaagg tatttaagac agtaaagtct gtttctttac tcaatttgtc tgttacattt
     1081 tccaactgag tcttactcat ttcatgggtc acaatcacta ggcgggctgt ttctccatct
     1141 gcagcttgtt gcagaatttg cttgaaggaa atttcttcag aattgaagat ttctgctaaa
     1201 cgaagcattt ttccattttt atcaggcgca tcaattgaga aataatattc gctcttcaca
     1261 tcgcttgggg ctgccaattg aagtgggcgg ctatattcgt taaaagcttt gccgatagta
     1321 ttgtctttca agcgacgaac gatacgaata atgtcagcca taacacttgt tgcagtcggt
     1381 ttttgcccag cacccggtcc atagtacata gactggccga tgccgataga ttcgacaaat
     1441 acagcattca tcacaccatt cacgcttgca agtggatgat ttttcggtag gaaggttgga
     1501 gatacttcgg cagcaatacc agaggtagtt tcttgaatat cacccacaag tttgatgaca
     1561 tagcccaatt cttgtgccac tgctacatct tctggtgtga tattcgaaat acccttgtgt
     1621 gctacgtgtt caaaatcaac tgtcatcccg aaagcaaatt gactgaggat aacagccttg
     1681 taagctgcat caatcccctc aacgtcattt gttgggtcag attctgcata gccaagttcc
     1741 tgtgctgttt gaagagcttt ttcgtaagtc cagccttcat caatcatctt agtcaacatg
     1801 aagtttgaag taccattcaa tacaccgagg atacgagtca ccttgtcagc agccaatgag
     1861 ttaaccaagg tacgcaagat tggaatacca cctgcaactg cagcttcata ataaagcgca
     1921 agacctttct cttcagccaa ggcacgcaat tcgctaccat gaacagcaag taaatcctta
     1981 ttggctgtta caatatgctt gcctgcttcc aaggcatgtg taataaatgt ttttgctggc
     2041 tcaatacgtc ccatcagctc aacgacgatg gcaatgtcct catcagctaa aatatcatca
     2101 atatttgtta caaaatgata gtcatgacct gcagccaaga gacggtcttt ttctgcttca
     2161 tccttgacca aaaccttagc aacttcaata ctatcatgcg cagctttctc tattttttcc
     2221 tgattttctt ctaataaaaa tggcacacca ctcgcaacgg ttccaaatcc taataatcct
     2281 atcttaacta ccatgtgctc tcctttaaaa tgtatttctc ccattataac aaatattctg
     2341 actatttggc aaaaaatttg atataattgt tttaata
//
LOCUS       DBNFCO010000134         2084 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.136, whole genome shotgun sequence.
ACCESSION   DBNFCO010000134 DBNFCO010000000
VERSION     DBNFCO010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2084)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2084)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2084
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.136"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            33..731
                     /locus_tag="AC1PIV_001902"
     CDS             33..731
                     /locus_tag="AC1PIV_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000276750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HIP6612880.1"
                     /translation="MYKILVVDDDFEIVKLMRTILEMKNYNVTTYQEVRLPIKISDFD
                     GFDLILLDVMMPNVDGLQICKQIRKSVSSPIIFVSAKDSEDDIVSGLNLGGDDYITKP
                     FSVNQLVAKVAAHLKREERYRNAESNESVIRELFPLTFYLQEKLVCVNGEAISLTKRE
                     YDILELLSSKTNKVYTREEIYECVYDDEADALFRSISEYIYQIRVKFGPYGINPIKTI
                     RGMGYKWNDEKVFN"
     gene            709..2052
                     /locus_tag="AC1PIV_001903"
     CDS             709..2052
                     /locus_tag="AC1PIV_001903"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HIP6612881.1"
                     /translation="MMKRYSINKRILRTVLEIVIGTVANVIMLLVLSYVLIFTGQLNT
                     YGTDYHISISDSKSANGIKNQMDYSVFDYVLFDSDNGELVSGNYQKQDLQHYKEVFDT
                     GSSVSEGSILFTKYENSDFILVIRRPTMPEFVNRNFRHISYNLVSYLFFIVLELLLIS
                     ISVIRLLREFTKNFRLIEKISLNMGIPGMDIGRKETAILECNNILLTLYQKDEELTKL
                     LEMEKKDKEDLSFQVAALAHDIKTPLTVLKGNIELLEMTNLDEKQLDFMSSMNHSVGI
                     FEKYFNSMVNYSRLLIEDKNYQEDIELSKFLDELSLECRDIMSSKKINFQIVNESHTR
                     VIKGNRLNLDRALINILSNATRFCSEEGKVVLTISESSNFISFEIWNNGLPFTEESLK
                     DGGKLFYTENKGRNDKHYGIGLSFAQKIAMRHQGQLILSNPQNGGAQVTLLIKKF"
BASE COUNT          746 a          251 c          385 g          702 t
ORIGIN      
        1 aatagtagta tgagataaaa gaggtaccta gtatgtataa gattttggta gttgatgatg
       61 attttgaaat tgtaaaattg atgcgaacaa ttttagaaat gaaaaactat aatgtgacga
      121 cttatcaaga agttaggctt cctataaaaa taagtgattt tgatggattt gatttaatat
      181 tgcttgatgt tatgatgcca aatgttgatg gtctgcaaat ctgtaaacag attcgtaaat
      241 cagtatcctc tccgattatt tttgtcagtg caaaagattc tgaagatgat attgtatctg
      301 gcttaaatct cggtggtgac gattatatca caaagccatt tagtgttaat caactagttg
      361 ctaaggttgc agcgcattta aaacgagaag aacgttatag aaatgctgaa tctaatgaat
      421 ctgttattcg agaattattt ccactaacat tttaccttca agaaaaactc gtgtgtgtta
      481 atggtgaagc tatttctctt actaaaaggg aatatgatat tttagagcta ttatctagta
      541 agacaaataa ggtttataca agagaagaaa tctatgaatg tgtctatgat gatgaagcag
      601 atgcattatt tcgttcaatt tcggaataca tttatcaaat tagagtcaag tttggtccct
      661 atggaattaa tcccattaaa acaataaggg ggatgggata taagtggaat gatgaaaagg
      721 tattcaatta ataagcggat tttaaggaca gttcttgaaa tagtgattgg tacagttgca
      781 aatgttatta tgttgcttgt attgagctac gttcttattt ttacaggtca gttgaacaca
      841 tatggaacag actatcatat ttcaattagt gatagtaaat ctgctaacgg tattaagaat
      901 caaatggatt attctgtctt tgattatgta ttgtttgata gcgataatgg cgaattggtc
      961 tctggaaatt atcaaaaaca ggatttacaa cattataaag aagtttttga tactggaagt
     1021 tcggttagcg agggttctat attgtttaca aaatatgaaa actcagattt tattttggtt
     1081 attagaagac caacaatgcc cgaatttgta aatcgaaact ttcgacatat ttcctataat
     1141 ttagtctctt atttgttttt tatagtgcta gaattattac tcatctctat ctctgttatt
     1201 aggctcttaa gagaatttac aaaaaatttt cgtctaattg aaaaaatatc tctgaatatg
     1261 ggaataccag gaatggatat tggacgtaaa gaaactgcaa tcttagaatg taataacatt
     1321 ttattgacgc tttatcaaaa agacgaagag ttgacaaagt tattagaaat ggagaaaaaa
     1381 gataaagaag atttgtcatt tcaagttgct gcattagcac atgatattaa aacaccatta
     1441 actgttttaa aggggaatat cgagttgctt gagatgacta atctagatga aaaacaatta
     1501 gattttatgt cctcaatgaa tcatagtgtt ggtatatttg aaaagtattt taattcaatg
     1561 gttaattact caagattgct aattgaggat aagaattatc aggaagatat tgaattatca
     1621 aaatttcttg atgaattatc attagaatgt cgagatatta tgtcttcaaa aaaaattaat
     1681 tttcaaatag ttaatgaatc ccataccaga gtgattaaag gaaatcgtct caacttagat
     1741 cgagctttga taaatatctt atctaatgcg actagatttt gttcagaaga gggcaaggtg
     1801 gtactgacta tatctgaaag ttccaacttt atcagttttg agatttggaa taatggttta
     1861 ccatttacag aagagtctct taaagatgga ggaaaacttt tttacacaga gaataaagga
     1921 agaaatgata agcattacgg aataggactt tcatttgctc aaaagatagc tatgagacat
     1981 caaggtcaat taatactctc aaatccacaa aatggtggtg cacaggtcac tttattaatt
     2041 aaaaaatttt aggggctggt caaaaagcct aatataaaca aaac
//
LOCUS       DBNFCO010000135         2038 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.137, whole genome shotgun sequence.
ACCESSION   DBNFCO010000135 DBNFCO010000000
VERSION     DBNFCO010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2038)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2038)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2038
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.137"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            <1..190
                     /locus_tag="AC1PIV_001904"
     CDS             <1..190
                     /locus_tag="AC1PIV_001904"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HIP6612882.1"
                     /translation="VNGFLVTPNSPLNLSKVILQLSENINLRKKIGNNSIERQKEHFS
                     LKSYVKNFSKVYTSLKVY"
     gene            578..1948
                     /locus_tag="AC1PIV_001905"
     CDS             578..1948
                     /locus_tag="AC1PIV_001905"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HIP6612883.1"
                     /translation="MKIISFTMVNNESEIIESFIRYNYNFIDEMVIIDNGCTDNTMQI
                     IFNLIKEGYKISVYDESLEAYNQYRLDNKYLTKIIAEKNPDLIIPLDADEFLTADSNP
                     RKLLEQLDLEKIHYVNWQWFVMTKKDDINESFIPRRMQYCFEKPVWHHSDGKPVTKCI
                     ISAKYYKKMNLKLSMGHHTVFGNPNVRIEHHNDLKFAHYRAISQEQLIYKTICYTIRD
                     IATMENNIETAQRTNQMALIESGVDMWETAREASYSGYDCNVIHAPIDLSFCKENIVI
                     KYNELSRETVAERVMKTGREMAVRAYNVERKQKEKKFLKPIIFVLDGLKGDEYIHPNP
                     SNHLTILTEMYNVRGLLTDNHQIKFLKVNYRLIITPDFAKFLPHEFIVVPDTLDIEQV
                     KSQYVGTGVDLSKIISLKEYRKEIGFIGNLYALLGFVPNMLNRIYLYIQRNGIANTII
                     KIKSRL"
BASE COUNT          764 a          261 c          361 g          652 t
ORIGIN      
        1 tgttaacggt ttcttagtca ctccgaactc accgttaaat ttatcaaaag taattcttca
       61 gttatcggaa aatataaatc tcagaaaaaa aattggtaat aattctatag aacgtcaaaa
      121 agaacatttt tcgttaaaaa gctatgtaaa aaatttttcg aaagtctaca cctccctcaa
      181 agtatactga ttggctgaag tgaatgcttt agtatagcga tttatcgtat tatcattcga
      241 taaaacaaat gttcagaaac agttataagt tatttctaaa gggcacctct ataaactccc
      301 aaaattgcga atttggagtt acgaaagcct tgttaaatca acatttaaat tttagaaaat
      361 tagtttttag agctccccta aaatagaaga taacagaagg gagccttcaa aaacttcatt
      421 tttaattgga ttgtagaaaa actgttaaat caatatttag atttttagga gttcagtttt
      481 tggggggaga gcttaataat ctatgcacta tatttcgaaa aatatatggt gtaaaatcag
      541 aactgatggt cgtggcaaaa aagagaatga ggaatttatg aaaattattt cttttacaat
      601 ggttaataac gaaagtgaga taatagagtc atttatacgg tataattata actttattga
      661 cgagatggtc attattgata atggttgtac agataacacg atgcaaatta tttttaattt
      721 gattaaagag ggatataaaa tatccgtata tgatgagtct ttagaggcat ataatcagta
      781 tcgacttgat aataaatatc taacgaaaat aattgctgaa aaaaatccag atttgataat
      841 acctttggat gcggatgaat ttttaacagc cgattcaaat ccacggaaac ttttggaaca
      901 actggactta gaaaagatac attatgtgaa ttggcaatgg tttgttatga ctaaaaaaga
      961 tgatattaat gaatcgttta taccacgtag aatgcaatat tgttttgaaa aacctgtttg
     1021 gcatcattct gatggtaaac cagttactaa atgtataatt tccgctaagt attacaaaaa
     1081 aatgaattta aagctatcga tgggacatca cactgttttt ggtaacccaa atgtaaggat
     1141 agaacatcat aatgatttga aatttgcaca ttatcgagct attagccaag agcaattaat
     1201 ttataaaaca atttgttaca ctattcgcga tattgctact atggagaaca atatcgaaac
     1261 agctcaaaga acaaatcaga tggcgctcat tgaatctggc gtggatatgt gggaaacggc
     1321 gagagaagcc tcttattcag gttatgattg taatgttata catgcaccaa ttgatttaag
     1381 tttttgtaaa gaaaatattg taataaaata taacgaacta tccagagaaa cagtagcaga
     1441 acgcgtgatg aaaacgggaa gagaaatggc tgttcgtgca tataatgtgg agcgaaaaca
     1501 aaaagaaaag aaatttctaa aacctattat atttgtatta gatgggttaa aaggagatga
     1561 gtatattcat cccaatccat caaatcattt gacgatctta actgaaatgt ataacgtcag
     1621 aggcttactt accgataatc accaaattaa atttctcaaa gttaattata gattaattat
     1681 aactccagat tttgctaagt ttttaccgca tgaatttatt gttgtaccag ataccttgga
     1741 tatagagcaa gttaaaagcc agtatgttgg tacaggtgta gacttgtcaa agattatttc
     1801 tttaaaagag tatcgaaaag agataggctt tattggtaat ttgtatgcgc ttttaggatt
     1861 tgttccgaat atgctcaata gaatttatct atatattcag agaaacggta ttgcaaacac
     1921 tattataaaa atcaagtcga gattgtgaga gttgtttact tttatttgta attttaaaag
     1981 taatgcaggc agataggaga aaaacgtttg gaaaaatgag aataagaatt aataattt
//
LOCUS       DBNFCO010000136         1988 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.138, whole genome shotgun sequence.
ACCESSION   DBNFCO010000136 DBNFCO010000000
VERSION     DBNFCO010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1988)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1988)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1988
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.138"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            <1..1015
                     /locus_tag="AC1PIV_001906"
     CDS             <1..1015
                     /locus_tag="AC1PIV_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002943315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HIP6612884.1"
                     /translation="LLNFINGIAIFMMIQSIRSGKLLVGNFVSLIQAITRVNTYSQSM
                     IQNTYIIYNTSLFMEQLFKFFDMEVSNISIQNSRISRIEKRIDKIKVNNLSFIYPGSV
                     KKTLEDINVEFNKGELVAIVGKNGSGKSTLVKLLSGLYQPSEGQIYYNNESSDVLDLS
                     YYQNNVSVLFQDFVKFELSVRENIGLSDVNSISDSKIKKHIDNLKLNFLTAENNFNLN
                     QRLGTWFNDSRQISGGQWQKVALARTFFKNASIYILDEPSSALDPVSEKEIFDEFVTR
                     SRDKIALFVSHNLMAASRADRIIVMQDGRIIDEGKHDDLISKSKYYRELYYSEKYEEE
                     SDG"
     gene            1008..>1988
                     /locus_tag="AC1PIV_001907"
     CDS             1008..>1988
                     /locus_tag="AC1PIV_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase C family protein"
                     /protein_id="HIP6612885.1"
                     /translation="MDENKVIIDLSEKVFAKFDEQLKRYAEQPNYDLLTLSSGLPGLI
                     LLSSELTSLTSERKYSARTGKYVNFMVKQMRNYGVLSDSLFSGVSGIGISILHLVEEH
                     PEYHNLLISFNEYIKYYTLSKIENIDIKKISPTDYDIIEGVSGVLVYLLSQEQDENDY
                     IINRIINFLSEFSLKNSTLTGFYVESKNQMSKTESKLYPLGCLNFGLAHGLAGVGAML
                     SYSKLKGYSNEKSIAAIKKIIMLYEKHELKNYMWKEGLSDIELKKTEKSNLQYEFIRD
                     AWCYGSPGISLLYLYSSLALEDKKLKSKACNILKASIRRSNGLEQSILCHG"
BASE COUNT          723 a          253 c          360 g          652 t
ORIGIN      
        1 tttattgaat tttattaatg gtatagctat ttttatgatg atacagtcaa ttcgaagcgg
       61 taaactttta gtaggtaatt ttgtaagcct tattcaagca ataactcgtg taaataccta
      121 ctcacaatct atgatccaaa atacttatat catctataac acaagtttat tcatggaaca
      181 attatttaaa ttttttgata tggaagtaag taatatttca attcagaata gtagaatctc
      241 aagaattgaa aagcgcattg acaaaataaa agtcaataat ctctctttta tctatccagg
      301 aagtgtcaaa aaaactttag aggatattaa tgttgagttt aataagggtg aacttgtagc
      361 aattgtgggg aagaatggtt ctggtaagag taccttagta aaattactat cgggattata
      421 ccaaccttca gagggtcaaa tatattataa taacgaatct agtgatgtcc tagacttgag
      481 ttattatcaa aataatgttt ctgttctttt tcaggacttt gtgaagtttg aattatctgt
      541 gagagaaaat attggcctaa gtgatgtaaa cagtatatct gactccaaaa taaagaaaca
      601 tattgataac ttaaaattaa atttcttaac cgcagaaaac aatttcaacc ttaatcaacg
      661 tttagggacc tggtttaacg atagtagaca aatttcagga ggacaatggc aaaaagtagc
      721 attggctagg actttcttca agaatgcaag catatacatt ttggatgaac caagttcagc
      781 gcttgatcct gtttcagaga aagaaatatt tgatgaattt gtaactcgtt ctagagataa
      841 gattgctttg tttgtgtcac ataatctaat ggctgcgagt agagcagatc gaattatagt
      901 tatgcaagat ggacgaatta ttgatgaagg aaaacatgac gaccttataa gtaaatctaa
      961 atattatagg gaactttact attcagaaaa gtacgaggag gagtctgatg gatgaaaata
     1021 aagttattat tgatttatct gagaaagtat ttgctaaatt tgatgagcag ttaaaaagat
     1081 atgctgaaca accgaattat gatttattga ccttgtcttc tggtttacct ggattgatat
     1141 tattatcttc agaattgaca agtttaacta gtgaaagaaa atactccgct agaacgggta
     1201 aatatgttaa ctttatggtt aaacaaatga gaaattatgg tgttttatcg gattctttat
     1261 tttcaggagt ttctggaatt ggaataagta tacttcattt agttgaagaa cacccagaat
     1321 atcataactt attgattagt tttaatgagt acattaagta ctatacgtta agtaagattg
     1381 aaaatataga tattaagaaa atctctccta cagattatga catcatagaa ggagtatctg
     1441 gagtattagt ttatctttta tctcaggagc aagatgaaaa tgattatata ataaacagaa
     1501 ttatcaattt cttatctgag ttttcactaa aaaattctac tttaacaggc ttctatgtgg
     1561 aatcaaagaa tcaaatgtcc aagacagagt ctaagcttta tccgttagga tgtctaaatt
     1621 ttggtttagc acacggcctt gcgggtgttg gcgcaatgtt gtcttattca aaattaaaag
     1681 gctattctaa tgaaaaatct attgcagcaa tcaaaaaaat tataatgtta tacgaaaaac
     1741 acgagttaaa aaattatatg tggaaagagg gattaagcga tattgaacta aagaaaacag
     1801 aaaaaagcaa tttacagtat gaatttattc gagatgcgtg gtgctacggt agcccaggaa
     1861 ttagtttact atatctgtat tcaagtttgg ctctagaaga taagaaacta aaatctaaag
     1921 cttgtaacat cttgaaagca tccatcagga gaagtaatgg tttggaacaa tctattttat
     1981 gtcacgga
//
LOCUS       DBNFCO010000137         1868 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.139, whole genome shotgun sequence.
ACCESSION   DBNFCO010000137 DBNFCO010000000
VERSION     DBNFCO010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1868)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1868)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1868
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.139"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            92..1384
                     /gene="purB"
                     /locus_tag="AC1PIV_001908"
     CDS             92..1384
                     /gene="purB"
                     /locus_tag="AC1PIV_001908"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HIP6612886.1"
                     /translation="MIERYSRPEMAAIWSEENKYEAWLEVEILADEAWAELGEIPKED
                     VALIREKATFDIDRILEIEEETRHDVVAFTRAVSESLSEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTTIIADKAREHKYTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNMERFDVAAKGVEAGKISGAVGNFANIPPFVEEYVCGKLGIRPQEISTQVLPRDL
                     HAEYFSALALIATSIERMATEIRGLQKSEQREVEEYFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVVRGHLVTAFENVALWHERDISHSSAERIITPDTTILINYMLNRFGNIVKNL
                     TVFPENMKRNMESTFGLIYSQRVMLSLIEKGMTREEAYDLVQPKTAQSWDNQVDFKPL
                     LEADERVTAKLSQEEIDELFNPDYYAKRVDDIFERLGL"
BASE COUNT          555 a          379 c          461 g          473 t
ORIGIN      
        1 gaatttagca gtcactacaa aactttagaa gataattata cattaagtta tattagtaac
       61 ttgatgcaac tagaagtaag gagcaaataa aatgattgaa cgttattccc gcccagagat
      121 ggcggctatt tggagtgaag agaacaagta cgaggcttgg ttggaggtgg aaatcctcgc
      181 tgatgaggct tgggctgagt tgggtgagat tcccaaggaa gatgtggcct tgattcgtga
      241 gaaggcgact tttgacatcg accgtatttt agagattgaa gaggaaactc gtcacgatgt
      301 ggtggctttc acgcgtgcgg tttcggaaag tcttagtgag gaacgtaagt gggtccacta
      361 tggtctgact tcgaccgacg tggtggatac ggcttacggc tacctataca agcaggccaa
      421 cgacatcatc cgtcgtgacc ttgaaaactt taccactatc atcgccgaca aggctcgtga
      481 gcacaagtac acgattatga tgggccggac ccacggtgtc catgcggagc caacgacctt
      541 cggtcttaaa ttagcaactt ggtatagcga aatgaaacgc aacatggagc gttttgatgt
      601 ggcggccaag ggcgttgagg ctggtaaaat ttcaggtgcg gttggaaact ttgccaatat
      661 tcctccattt gtggaagaat atgtttgtgg caaattgggt attcgtccgc aggaaatttc
      721 gacccaggtt cttcctcgtg accttcacgc agaatatttc tcagccctag ccttgattgc
      781 aacgtctatc gagcgtatgg cgacagagat ccgtgggcta caaaaatctg aacaacgtga
      841 agtcgaagag tatttcgcca aaggccaaaa gggtagctct gctatgcccc ataaacgcaa
      901 ccctatcggc tctgaaaata tgaccggtct ggctcgtgtg gtgcgtggtc acttggtgac
      961 ggcttttgag aatgtggctc tctggcacga acgcgatatt tcccactcgt cagcggagcg
     1021 gattatcacg ccggatacga ccattctcat caactatatg ctcaaccgtt ttggcaatat
     1081 cgttaagaac ttgacggtct tccctgaaaa tatgaaacgc aatatggagt caacctttgg
     1141 cttgatttac agtcagcgtg tcatgctcag cttgattgag aaaggcatga cacgtgagga
     1201 agcctatgat ttggtgcaac caaaaacggc gcaatcatgg gacaatcaag tggacttcaa
     1261 gccccttctc gaagcggatg agcgtgtgac tgccaaactc agtcaggaag aaatcgatga
     1321 actcttcaac cccgactact atgctaagcg ggtggatgac atctttgaac gacttggatt
     1381 ataaaaaaat caaaattctt tggattttcc agagaatttt tttgtttact tgcgaataaa
     1441 taggtgaagg ggaaaacaag ctccctccgc tagacaatca ttcgtaagag gatgagcaga
     1501 aagtccagcc tagcttctca gagttcgtat caacatttca gcgcagtggt tgattggcag
     1561 attcgttcgc gtttcacgct ccaaatctga cctaatcaac tgtgcggggt gggaagacga
     1621 actctttaga ttggtcgagt tctgtcccac tcccaaaatt ttacgaatag ataagtgtag
     1681 gggaagcaag ctcacaactt attcaaaaaa ataagatttt ttcaaaaaaa agaaaacgat
     1741 ttgcgaataa gtatagtgag agggaaaatc cccctcaagg agatacacac ttgaaaaaaa
     1801 taaatcattt tcaaaatgat ttacgaataa acaagtgtag gaaaaatgaa aggagaagaa
     1861 ggatgaaa
//
LOCUS       DBNFCO010000138         1805 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.140, whole genome shotgun sequence.
ACCESSION   DBNFCO010000138 DBNFCO010000000
VERSION     DBNFCO010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1805)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1805)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1805
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.140"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            <1..653
                     /locus_tag="AC1PIV_001909"
     CDS             <1..653
                     /locus_tag="AC1PIV_001909"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HIP6612887.1"
                     /translation="IIDYKNSVNFQLDYVVINDGSTDSTKEILIQNKLNAVHLVQNLG
                     IGGAVQTGYKYALDNDYDVAVQFDGDGQHDIRSLNGLIQPILVGQADMVIGSRFVGDT
                     LSEFQTSFMRRFGIGVISNMIKLTTGNRIWDTTSGYRLGNRKVIAQFAKRYPIKYPEP
                     ESTVHLLKQNFQVVEAPANMFERAGGVSSITPFKSIRYMVEVCSSILIASLMKEGE"
     gene            653..1009
                     /locus_tag="AC1PIV_001910"
     CDS             653..1009
                     /locus_tag="AC1PIV_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2304 domain-containing protein"
                     /protein_id="HIP6612888.1"
                     /translation="MTIQALAMFLASLGFLYFIFRNINKNKILFEHAFMWIVIGFGLI
                     VFALFDVIPIKLAYLFGFGLTSNFLLSVAIFVLLVIGFLHSMALSQQKQQIKNLIQEV
                     SMAKKRISELEEHHAE"
     gene            999..1769
                     /locus_tag="AC1PIV_001911"
     CDS             999..1769
                     /locus_tag="AC1PIV_001911"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HIP6612889.1"
                     /translation="MQNNHTFVICAYGDSKYLEECIHSLKQQTLQSQLILYTSTPSEY
                     IEQICQKNAIVMHTAQGGGIGKDWNLALSFVTTPYATIAHQDDIYLPDYCEKIMSQMT
                     EETLIAYSDYQEVKEGVAIPLTSNLKIKQLMLRTMAMFPKWKFWRNRVLAFGNPISCP
                     AVTYNLKKLNDFKFNEEMKVSLDWFAWYQIAQKNGSFTFVDESLMYHRIHEESETTNS
                     IENNIRTQEDYEMYLLFWPKFIAKFLLSYYVKSQETNN"
BASE COUNT          573 a          276 c          356 g          600 t
ORIGIN      
        1 gaattataga ttataaaaat agtgtgaatt tccaattgga ttatgttgtc atcaatgatg
       61 gttcaacaga tagcacgaaa gaaattttga ttcaaaataa attaaatgct gttcatctag
      121 tacaaaattt aggtattggt ggagctgttc agacgggata taaatatgcc ttggacaatg
      181 actatgacgt agcagttcaa tttgatggtg atggtcagca tgacattcgt tcattaaatg
      241 gcttaattca gccaatctta gttggtcagg ctgatatggt gattggctca cgctttgttg
      301 gtgatacttt gtcggaattt caaactagct ttatgagacg atttgggata ggtgttattt
      361 caaatatgat taaattaaca actggaaacc gaatttggga tactacatca ggttatcgtt
      421 tgggaaatag aaaagtgatt gcacaatttg caaaacgata cccaattaaa tatccggaac
      481 cggaatcaac tgttcattta ctaaagcaaa atttccaagt agtagaagca ccggccaata
      541 tgtttgaaag agcgggaggg gtttcttcga ttactccatt taagtccatc cgctacatgg
      601 tagaagtttg ctcatctatt ttgattgctt cgcttatgaa ggagggggaa taatgactat
      661 acaagcatta gctatgtttc ttgcctcgct aggttttttg tattttattt ttaggaatat
      721 taataaaaat aagatcttat tcgaacatgc ctttatgtgg attgttattg gcttcggact
      781 gattgttttt gcactctttg atgttattcc tattaaattg gcctacttat tcgggtttgg
      841 tctgacttcc aatttcttgt tatctgtggc aatttttgtt ctcttggtaa ttggattttt
      901 gcatagtatg gctttatctc aacaaaagca gcagattaaa aatttaattc aagaagtatc
      961 aatggctaaa aaaagaatct ctgaattgga ggagcatcat gcagaataac catacatttg
     1021 ttatctgtgc ttatggagat agtaagtatc tagaagaatg catccattcg ttaaagcagc
     1081 aaacacttca atcacaactc atcctataca ctagtactcc gagtgaatat atagaacaaa
     1141 tttgccaaaa gaatgcaatc gtaatgcata ccgcacaagg aggaggtatt ggaaaagatt
     1201 ggaatttggc actctctttt gtaacaaccc cttatgctac aattgctcat caagatgata
     1261 tttatttacc agactattgt gaaaaaataa tgtctcagat gacagaggaa acgttgattg
     1321 cttattcaga ttaccaggaa gttaaggaag gtgtggctat tcccttaact tcaaatttga
     1381 aaatcaagca actcatgtta cggacaatgg ccatgtttcc caaatggaag ttttggcgga
     1441 atagggtttt agcctttggt aatccaattt cttgtccagc tgtgacctat aatttgaaga
     1501 aactgaatga tttcaagttt aatgaagaaa tgaaagtttc tcttgattgg tttgcttggt
     1561 atcagattgc acaaaaaaat gggagcttta cctttgtaga tgagagtttg atgtatcatc
     1621 gtatccatga ggaatctgag acgacaaata gcattgaaaa caatattcgt acacaagaag
     1681 actatgaaat gtatttgttg ttctggccaa agtttattgc caagtttctc ctgagttact
     1741 atgttaagag tcaagagacg aataattaaa atattttagt taccaatcat tgtattccca
     1801 tcaat
//
LOCUS       DBNFCO010000139         1803 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.141, whole genome shotgun sequence.
ACCESSION   DBNFCO010000139 DBNFCO010000000
VERSION     DBNFCO010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1803)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1803)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1803
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.141"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            <1..710
                     /locus_tag="AC1PIV_001912"
     CDS             <1..710
                     /locus_tag="AC1PIV_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HIP6612890.1"
                     /translation="LQSGGIKLTTYIEDIMGLSGRNLLQLLVDGTPITPRIVHQSVYT
                     SLKKKVPQLLEALDDYFSDHHRFMLKQSLEIYDFYQKQIELLEERMNVYLSQYEKHVE
                     ILDSIPGIDVITASVIISEVGVDMSQFPTFGHLASWAGLCPGNNESAGKKRSTKIRHG
                     NSYLKKCLCQAAFAVKRQKGSPLAERYYQIQSRRGSQKATIALAHQLLKIAYILLKEQ
                     MTYPEFLAQKKRLLGTS"
     gene            complement(945..1412)
                     /locus_tag="AC1PIV_001913"
     CDS             complement(945..1412)
                     /locus_tag="AC1PIV_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HIP6612891.1"
                     /translation="MTIRKARQSDIPILNELLQDILQVHHQARPDIFKSAGQKFSEAE
                     LVALLENPDKPIFVFELEGQVVGHLFCELSTATGDVLEPIKTLFIDDLCVANSARGQR
                     IGEQLYEFALSYAKEQGCHNLTLDVWADNAGAVRFYERQGMKPQKFRMEQIIE"
BASE COUNT          552 a          368 c          344 g          539 t
ORIGIN      
        1 ttcttcagtc aggtggtatc aagctaacaa cctatattga agatattatg gggctatctg
       61 gtcgcaatct ccttcagcta ctggttgatg ggacgcctat tacacctcgc attgtccatc
      121 aatcagttta caccagcttg aagaagaaag tgccgcagct tctggaagcc ttggatgact
      181 atttttctga ccatcaccgc tttatgttaa agcagtcctt agagatttat gatttttatc
      241 agaagcagat tgagttgttg gaagagcgaa tgaatgtcta tctatcacaa tatgaaaaac
      301 atgtagaaat attggattcc atcccaggca ttgatgtcat tacagcttct gttatcattt
      361 ctgaggttgg agttgacatg agtcagtttc cgacatttgg acatttagct tcttgggctg
      421 gactctgtcc aggtaataat gagagtgctg gtaaaaaacg aagtaccaag attcgacacg
      481 gaaattcata tttgaagaaa tgtttatgcc aagcggcctt cgctgtcaaa agacaaaaag
      541 gcagcccatt agcagaacga tattatcaga ttcaaagtcg gcgtggctca caaaaagcaa
      601 ccattgcact tgcgcatcaa ctattaaaaa tagcctatat ccttttaaaa gaacagatga
      661 cttatcctga atttttagca caaaaaaaaa gactactagg gacgagctag tagcctaaca
      721 taaaaaattt ttcgctttga ttatatcata gggagggagt ttttgcattc ttttgagttt
      781 tcgtataaga actcgaccaa gataaaaaga gttcgtcttc ccacccccgc acagttgatt
      841 aggccagatt tggagtgcaa aacacgaaca aatctgccaa tcaaccactg cgctgagatg
      901 ttgacacgaa ctctgagtag tggtcctggg ctttttgccc agcctcactc tattatttgc
      961 tccatacgga acttttgtgg tttcattcct tggcgttcat aaaaacggac agctcctgca
     1021 ttgtcagccc atacatccaa ggtaagattg tggcaaccct gctccttagc ataggaaaga
     1081 gcaaattcat aaagctgctc gccaattctt tgaccacgcg cagaattggc tacacacaaa
     1141 tcatcaataa acaaggtttt aattggttct aaaacatcgc ctgttgcggt agataattca
     1201 caaaaaagat gcccaaccac ttgtccctct aactcaaaga caaaaatagg cttatctgga
     1261 ttttccaaaa gtgctactaa ttcagcctca gaaaattttt gacctgcact tttaaaaata
     1321 tctggtcgtg cttggtgatg cacctgtaaa atatcttgaa gcaattcatt taatatcgga
     1381 atgtcagatt gtctagcttt acggattgtc ataatactct ccttttgagt ttttattatt
     1441 atagcacatg ttcatttttt aacaaaatag gtctacagac cgatgaagaa tctgaaaatt
     1501 cgagtatact ataggtgtat cctaaaattt ttcataaatc tcctaaaaaa tcagctggcc
     1561 aaggctggtt ttttgttgtc ttaaaacgag aatgtgtagt gtagaaaact actaaagttt
     1621 ctctctcttt gacgcaaaat gcttttgctt catttccaac ctcccagagt cactcccctg
     1681 actctgggag ccccaaaaca cagaaacata ctaagattag tagtgaggaa atctccgacg
     1741 ggagaaagta ctcactactt tttctttatg ataaagtaga ggtgtcttgt taagtcgtag
     1801 ggc
//
LOCUS       DBNFCO010000140         1688 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.142, whole genome shotgun sequence.
ACCESSION   DBNFCO010000140 DBNFCO010000000
VERSION     DBNFCO010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1688
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.142"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(100..444)
                     /locus_tag="AC1PIV_001914"
     CDS             complement(100..444)
                     /locus_tag="AC1PIV_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SSU0592/SSU0593 family protein"
                     /protein_id="HIP6612892.1"
                     /translation="MKHIVTKRNYKVGACAMALALLMTTAGGAVVNAEQHLESSVGLV
                     QRGDVLLKLKESNQSFNEGEVGNLEPVNPTVPPMASSVQKSWFSSFWGGVKTFWNALC
                     CSVGLTGLKVSK"
     gene            complement(911..1615)
                     /locus_tag="AC1PIV_001915"
     CDS             complement(911..1615)
                     /locus_tag="AC1PIV_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HIP6612893.1"
                     /translation="MKIHVVNNQVEGATVALDILREKLNGGTKVLGLATGSSPLEFYR
                     LIRESDLDFSDVTSVNLDEYVGLGEESDQSYIHFMKENLFNTKPFKQSYLPNGLATDV
                     VAETERYNKILAEHPVDFQILGIGRNGHIGFNEPGAPFDGQTHLVELAPSTIEANARF
                     FDNPEDVPKQAISMGIANIMAAKTIVLMAYGQEKADAIKATVEGAVTEDVPASVLQNH
                     DNVILILDQAAASKLV"
BASE COUNT          544 a          345 c          274 g          525 t
ORIGIN      
        1 gagggtaata tatagaaaat taaataattt aagaaagcta gtgaagtatg aaggatttgc
       61 aaattaatta actaaatatt acaagattat aactctatgt tacttactaa ctttgagccc
      121 agttagtccc acagaacaac ataatgcatt ccagaatgtt tttacaccac cccaaaatga
      181 actaaaccat gatttttgta cagaagaagc cattggaggc acagttgggt tgacaggctc
      241 taaatttcca acctctcctt cattgaaaga ctggtttgat tctttcaatt ttagaagtac
      301 atcaccacgc tgtactaagc caactgatga ctcaaggtgc tgctctgcat ttacaactgc
      361 accacctgca gtagtcatca acaatgcaag tgccatagcg catgcgccaa ctttataatt
      421 acgttttgtt acaatatgtt tcatgatgaa acatctcctt tgtatagata tttgcttcct
      481 cctatcggaa acgtagtaac agtatagcac aaaaaaataa ctcaaaaacc aactttagaa
      541 aaagattata taaaaaccag aaaactacct gaaaaaattg aaaacgttat acaaaacgta
      601 gagaaaatga tactatttcg cccatttcac ttatccctat caattttcaa catgataaag
      661 gatggcaata cctcttgttg aaattttctc tcacatccaa cttaatgtta tatataatcc
      721 attcaaatat ataacaactg atatggatta tcagaatagc aaaaggcatg cccttaaaaa
      781 tataagttac atgccttttc acaatttttg tcaaattcat aatggaaaaa gaacctagat
      841 tcattcagaa attatactta ttgtactgtt acaaccaact ttatgtctaa gaataatcgt
      901 ttacaacata ctacactaat ttactcgctg ctgcttggtc gaggatgagg atgacattgt
      961 catggttttg gaggacgctt gctgggacat cttctgtcac tgccccttcc acagtcgcct
     1021 taatggcgtc agctttttcc tgaccatagg ccatgagaac aatggtcttg gctgccataa
     1081 tgttggcgat gcccatggag atagcttgtt ttggtacatc ttctggattg tcaaagaagc
     1141 gggcgttggc ttcaatggtt gatggcgcca attcaaccag atgggtctga ccatcaaatg
     1201 gagcacctgg ttcgttgaaa ccgatatggc cgttgcgacc gatacccaaa atttggaaat
     1261 caaccggatg ttcagccaaa attttattgt aacgttctgt ttcagcaact acatctgtcg
     1321 ccaaaccatt cggtaaataa gattgtttaa acggtttggt attgaaaaga ttttccttca
     1381 taaaatgaat ataggattgg tcgctctcct cacctaaacc aacatactca tccaagttta
     1441 cagatgtcac atccgaaaag tctaaatccg actcacgaat caatctgtaa aattctaacg
     1501 gactggagcc tgttgccaaa cctaatacct tggtacctcc gttcaatttt tctctcaaaa
     1561 tgtctaatgc tacagttgct ccttcaactt gattgtttac tacatgaatt ttcataacac
     1621 acctctttgg tctataccat tttgtttttc tttattatat ggtatagacc aatttttgtc
     1681 aagaattt
//
LOCUS       DBNFCO010000141         1646 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.143, whole genome shotgun sequence.
ACCESSION   DBNFCO010000141 DBNFCO010000000
VERSION     DBNFCO010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1646)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1646)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1646
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.143"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            211..576
                     /locus_tag="AC1PIV_001916"
     CDS             211..576
                     /locus_tag="AC1PIV_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HIP6612894.1"
                     /translation="MARDGRKEGKKSLIPSFCDYFSINYTGSNALTVSLCRNKFIWGA
                     IADYFNIPTPKTVCIKDGEVLGEPFEAQKYIRKEISESASINLSNDSIMNNFEWKNIE
                     KKIFCCKSVFQELKLKSLF"
     gene            635..919
                     /locus_tag="AC1PIV_001917"
     CDS             635..919
                     /locus_tag="AC1PIV_001917"
                     /inference="COORDINATES: protein motif:HMM:NF019121.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612895.1"
                     /translation="MTSKLSDNNSYSFEWLEDQQICTKLKESTKKLAKYLGITTYGRV
                     DFRIKSDGSYFVFDIATMPYTTDHRSFNFNFEQYGLTMTDLHKLVILSSL"
     gene            complement(914..>1646)
                     /locus_tag="AC1PIV_001918"
     CDS             complement(914..>1646)
                     /locus_tag="AC1PIV_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DNA repair protein"
                     /protein_id="HIP6612896.1"
                     /translation="NDANKALKFFNDVDDEIEQYYTLGSLLGLLLVSSNYERANQVKQ
                     EIETLSDKHNLPLYWKSKNNFVVLDFLSGMEGDFDYWKSRFESILTEYELNDVSKHLM
                     YTNLCAISLYYSKTKGYRSYKTILEELMDVEDLADLEDTSIDDFYRYYFGWFEFCLLL
                     LESKHRQAKNKYNQLKDFSPIIFNSNKKLLIEKHRRYKKIFESNIKTGKEFSEFLSQS
                     KFASREWNYFRRGLMLTDIQYTSAL"
BASE COUNT          576 a          238 c          248 g          584 t
ORIGIN      
        1 ttacaaaaac aaactaaaaa aatgtcttat tatacaattg aacatgcatc tggtcgtgaa
       61 tttttttcgc tatcagaatt tgaggaaata gcttcagcac tgttaaaaac tggtttatgt
      121 ttgaacattt tttatactga aatagatttc gtggagtata tattaaaata ctattagcgc
      181 ttatcaaaag aaactttgtt agtttataat ttggctagag acggtcgaaa agaaggaaaa
      241 aaatcgctga ttccctcttt ttgcgattac tttagcatta attatacagg ttcaaatgca
      301 ctaacagttt cattatgtcg taataaattt atttggggag ctattgcaga ttactttaat
      361 attccaacac ccaaaactgt ttgtataaaa gatggcgagg tattaggtga gccttttgaa
      421 gctcaaaaat atattagaaa agaaatttcg gaatctgcaa gtattaatct ttccaatgat
      481 tcaataatga ataattttga gtggaaaaat atagaaaaaa agattttctg ttgcaagagt
      541 gtatttcagg aattgaagtt gaagtccctt ttttaatatt aaagggaaat atcttgtatt
      601 agatccagtc aaaattgtct cttcttcaga aattataaca agcaaactat ctgataataa
      661 tagttattca tttgaatggt tggaagatca acaaatatgt acaaaattaa aagagtcaac
      721 aaaaaaactc gccaagtact taggtataac cacttacgga cgagttgatt ttagaataaa
      781 gtcagatggg agttattttg tttttgatat tgcaacaatg ccttacacaa ctgaccatcg
      841 ttcatttaat tttaactttg agcaatatgg acttacaatg actgatcttc ataaactagt
      901 aatattaagt agtttataat gcactagtat actgtatatc agttagcata aggcctcttc
      961 gaaagtaatt ccattctctt gaagcaaact tggattgtga tagaaattca gaaaattcct
     1021 ttcctgtttt tatatttgat tcgaaaatct ttttatagcg acgatgtttt tcaattaata
     1081 attttttatt tgaattgaaa ataataggtg agaaatcttt taattgattg tatttatttt
     1141 ttgcttgtcg atgcttactc tctagtaaca acaagcaaaa ttcaaaccat ccaaaataat
     1201 aacgataaaa atcatctatt gaggtatctt caaggtcggc taagtcctca acatccatca
     1261 attcttcaag tatcgtttta tagcttctgt acccttttgt tttagaataa tatagagaaa
     1321 ttgcacataa atttgtatac attaagtgtt tactcacatc atttaactca tattcagtaa
     1381 gaatgctttc aaaccgagat ttccaataat caaaatctcc ttccatacct gaaagaaagt
     1441 ccagtacaac aaaattattt ttagatttcc agtatagtgg gagattgtgt ttatctgata
     1501 gtgtttctat ttcttgtttc acctgatttg ctcgctcata gttggaagaa acaagtaata
     1561 atcctagaag actaccaagt gtataatact gttcaatttc atcatcgaca tcgttaaaaa
     1621 attttaaagc tttattggca tcattg
//
LOCUS       DBNFCO010000142         1520 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.144, whole genome shotgun sequence.
ACCESSION   DBNFCO010000142 DBNFCO010000000
VERSION     DBNFCO010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1520)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1520)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1520
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.144"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(1..870)
                     /locus_tag="AC1PIV_001919"
                     /pseudo
     CDS             complement(1..870)
                     /locus_tag="AC1PIV_001919"
                     /inference="COORDINATES: protein motif:HMM:NF019371.6"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Abi family protein"
BASE COUNT          470 a          276 c          210 g          564 t
ORIGIN      
        1 atttcactat aataatcggc agagcaatgc ggtttgaata aacaccttct tttagttcgt
       61 ataagagctc cttccattct tcacgaagta ttggtgttgt atgcatttta agatcaataa
      121 tattcgaatt atgagcacac atattacgta ataaattcaa acatttcaac caagaaagta
      181 actcagcatc actgcaatca tattgtttag ctatttgtct aatattattt gttgacatca
      241 attcgataag gttgattatc tgaccgaacg tcattaggtt aatagccaac caaattggag
      301 gatatttcat attgtcaatt ttcaattttt ccttgatttc tggagaagtt gttcttttca
      361 attcagcttt gagctgcttt ttaaatttct cttctcgata ttttaggtaa tgcttgcagt
      421 actctttttt attgcaccac tgtgagaaat ttaaatatcc atatggccct aatctcctat
      481 aacctaaaac aaatgctact tgggttttaa agctacctca atgtcttcga gagcatccaa
      541 tagatggaga cgcaatcgtt tatcttgata atatctaaca gtaatttttt tgaatggggt
      601 gttttggtaa tttatttgac gcactccatc aactgtcaca atttttgaaa aaggtctagc
      661 aaattccttt aatttatagt aagaaattat tgataacttt tgctcagctt ttttcttgtc
      721 ctgctctcca gaaaacagca tgcctcttga ttctaacaaa gcaacttgtt cctcaaaact
      781 tttatgggaa aaactactca tttgaacact ccttaaacaa aaaaaccacc catcagaaca
      841 tgtctgtgca attgaagcaa gggcggccat tgatatttca agttcattat atagtatatt
      901 tgaatatacg tcaagttttt tatcaagaaa atctgagaaa ttagctgatt ttattatttt
      961 tgctctacga ctaacatcta aaaatgtaca attgctccaa tctcctcccc tctattttct
     1021 actacatttt gtacaattgg atttctaaca ctaatacaat aatatgcttt aatcctgtac
     1081 cttattgaat cctaaaataa tgtacaaaat aaaaataaag tacatttttt gaagaatgta
     1141 ctttatgctt ctatctcagt attatcaagg gttcaggcta tattaggtca attgttcata
     1201 attttttagt tttcgagata actagaaaat ttttttcacg tccaaaatcc taaaaatcta
     1261 gattatttct cggtaaactc acatagcatt agaatcttct tcgcaacctc ttctggcttc
     1321 aaactgtctg ttttaaacct ttgtcctgga atctgacttt caaaagattt taatactctt
     1381 cgaaaatcaa aatcagacgt tgttgacttg ttttgatgaa cttcagttct atctgcatct
     1441 acgtcgccta gtcagatttt gattttcatt gagtataaac aatcatcaag atgtcttttg
     1501 gcccagatgt tgtcttcatt
//
LOCUS       DBNFCO010000143         1511 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.145, whole genome shotgun sequence.
ACCESSION   DBNFCO010000143 DBNFCO010000000
VERSION     DBNFCO010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1511)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1511)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1511
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.145"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(<1..>1511)
                     /locus_tag="AC1PIV_001920"
     CDS             complement(<1..>1511)
                     /locus_tag="AC1PIV_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="HIP6612897.1"
                     /translation="MELFDSNLGIGSPYGYQHPKNDFWESSPSTVYFSEKEELEYLNN
                     FEKALETGGNIQLYNEEDFFNQDKDKINLGFELFFYVNKVDGKSVLSLTNTGCSKNLG
                     ASSGRFSILSDKLEHYHQTITQIVENNNHVSGYNSCEITFLPENLRHANVMRTTNVRE
                     KVLSLFTNMDKRSQILSDIYIGIDSKNSFYARNFKTKELLKFYSTNMYNQMMFSNELR
                     FLCEIAQEDHFGIFPWEMVYQKFSHIPRIVFKDIIVAPERWRLSGRMLSKDIHQIILE
                     NNLPTKLYVDNSDNRILINRNNPLDNQLFEDIVRKSSNKNEELCLSECIFDSHLVEKE
                     STTHISDIVVPVFAKDEIKEPRYIKEILPEVIPTNVRQKIPFDEWLYFKLYMSADRQE
                     EFLSDIMPQILKLVNLDDGMSFYIRYTDPKFHIRLRIRTQNLYKSFEKIQEIFQLCIQ
                     NKLISNIDISTYDREIERYGGLERIPLVEEIFCLDTEIVINSLSLIRQKRLDL"
BASE COUNT          502 a          262 c          188 g          559 t
ORIGIN      
        1 taaatctaat cttttctgcc gaattaaact taatgaattg atgactattt cagtatctag
       61 acaaaaaatt tcttctacca aaggaattct ttctagtccc ccataccttt cgatttctct
      121 gtcatacgtt gaaatatcta tatttgatat taacttgttt tgtatgcaga gttgaaaaat
      181 ctcttgaatt ttttcaaaac ttttatataa attctgcgtt cttatcctta gtcggatatg
      241 aaattttgga tcagtatatc tgatatagaa gctcatccca tcatctaaat ttactaactt
      301 caaaatttga ggcattatat ccgaaagaaa ttcctcttgc ctatctgccg acatatacaa
      361 tttaaagtag agccattcat caaatggtat tttctgtcta acatttgtcg gaataacctc
      421 tggtaatatt tcttttatgt acctaggttc cttaatttca tccttagcaa atactggaac
      481 aactatatca gaaatatgag ttgtagattc cttctctaca aggtgtgaat caaaaataca
      541 ctctgataga cataattctt catttttatt actacttttt cttacaatat cttcaaaaag
      601 ttgattatct agtggattat tacggttaat taatattcga ttatcactgt tatcaacata
      661 caattttgtc ggaagattgt tttcaagaat aatctgatga atatccttcg acaacatcct
      721 tccactaagc ctccaacgtt caggagcaac aataatgtcc ttaaatacta ttctaggaat
      781 atgagaaaat ttttgataaa ccatctccca agggaatatt ccgaaatgat cttcttgagc
      841 tatctcacat aaaaaccgta attcattgct aaacatcatt tggttataca tatttgtact
      901 ataaaatttt aagagttcct tagttttaaa atttctagca taaaaactat tcttagaatc
      961 aataccaata tatatatcag ataaaatttg acttctctta tccatattcg taaaaagtga
     1021 taatactttt tctctgacat ttgttgtgcg cataacatta gcatgacgaa gattctctgg
     1081 taaaaatgtt atttcacaag agttataccc tgatacgtga ttattgtttt caacaatttg
     1141 agtgatagtt tgatgataat gttccaattt atctgataga atagaaaacc tgcctgagct
     1201 agctcctaaa ttcttagaac atcctgtatt agttaagctt agtacgcttt taccatctac
     1261 tttattaaca taaaagaaca actcaaatcc tagattgatt ttatctttgt cttgattaaa
     1321 aaaatcttct tcattataaa gttgaatatt tccacctgtt tctaaggctt tttcaaaatt
     1381 attgagatat tctaattctt ctttttcact aaaatataca gtagaaggcg aagattccca
     1441 gaaatcattt ttggggtgct gatatccata tggagaacca attcctaaat tagaatcaaa
     1501 caactccatc a
//
LOCUS       DBNFCO010000144         1500 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.146, whole genome shotgun sequence.
ACCESSION   DBNFCO010000144 DBNFCO010000000
VERSION     DBNFCO010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1500)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1500)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1500
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.146"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            66..151
                     /locus_tag="AC1PIV_001921"
     tRNA            66..151
                     /locus_tag="AC1PIV_001921"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:100..102,aa:Leu,seq:aag)
     gene            386..1267
                     /locus_tag="AC1PIV_001922"
     CDS             386..1267
                     /locus_tag="AC1PIV_001922"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HIP6612898.1"
                     /translation="MPLVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKQAP
                     VLIQTSMGAAKYMGGYKVARNLIANLIESMNITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLAKAKEVVELAHAKGISVEAEVGTIGGEEDGIVGSGELAPIEDAV
                     AMVATGIDFLAAGIGNIHGPYPANWEGLDLDHLRKLTEAVPGFPIVLHGGSGIPDAQI
                     QEAIKLGVAKVNVNTECQIAFANATRKFAAAYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSANKA"
BASE COUNT          488 a          270 c          336 g          406 t
ORIGIN      
        1 aaaataaaat tcaaaaaaag tgttgacaag gctagttcct aatgatatac tagttcttgt
       61 gttaagcggg gatggcggaa ttggcagacg cgcaggacta aggatcctgt gaccgcttta
      121 ggtcgtgtgg gttcaagtcc cactctccgc atagtggact agctaaggct agtccttttg
      181 ctttgtctag ataagtgcag agcacgatat atgctagttc ataaattaca agaatgatac
      241 gaaacaggca ttattatggc tttcatgaaa agatatgtga aagttttctc aaaactagac
      301 ggtttcaact agcattttca aaataaaaat ggtagaatag aagagtatga ggtgcaacct
      361 caaaaaatat taggaggcta tcgaaatgcc attagtttca gcagaaaaat ttgtccaagc
      421 agctcgtgac aacggttatg cagttggtgg atttaacaca aacaaccttg agtggactca
      481 agctatcttg cgtgcagcag aagcaaaaca agctccagtt cttatccaaa cttctatggg
      541 tgcagctaag tacatgggtg gttacaaagt agctcgtaac ttgattgcaa acttgattga
      601 atcaatgaac attacagttc cagttgctat tcaccttgac cacggtcact acgaagatgc
      661 acttgagtgt atcgaagttg gttacacttc tatcatgttt gacggttcac accttccagt
      721 agaagaaaac cttgcaaaag caaaagaagt tgtagaattg gcgcacgcta aaggtatctc
      781 agttgaagct gaagttggta ctatcggtgg tgaagaagat ggtatcgtag gtagcggtga
      841 attggctcca atcgaagatg cagtagcaat ggttgcaact ggtatcgatt tcttggcagc
      901 aggtatcggt aacatccacg gtccataccc agcaaactgg gaaggtcttg accttgacca
      961 cttgcgtaaa ttgactgaag ctgtaccagg tttcccaatc gtattgcacg gtggttcagg
     1021 tattccggat gcacaaatcc aagaagcaat caaattgggt gttgctaaag ttaacgtaaa
     1081 cactgagtgc caaatcgcat ttgcaaacgc aactcgtaag tttgcagcag cttatgaagc
     1141 aaacgaagca gaatacgata agaaaaaact ctttgaccca cgtaaattct tggcagacgg
     1201 cgtgaaagct atccaagcat ctgttgaaga gcgtatcgac gtattcggtt cagcgaacaa
     1261 agcttaatgt aactgcgaag aaatcttaga tttcaagcaa acaaagcata agtttcttag
     1321 attaaaccaa aaaggatttt ctttcgagaa tcctttttat tataatagtt gattaagttt
     1381 gatctagttc tttgctatga agaaatctac gatagaagtg agcagagaac agttaaaata
     1441 taaactgctc caaagttttc atgactgtaa taacttagag aacgaagaat tatggatggg
//
LOCUS       DBNFCO010000145         1415 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.148, whole genome shotgun sequence.
ACCESSION   DBNFCO010000145 DBNFCO010000000
VERSION     DBNFCO010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1415
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.148"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            <1..415
                     /locus_tag="AC1PIV_001923"
     CDS             <1..415
                     /locus_tag="AC1PIV_001923"
                     /inference="COORDINATES: protein motif:HMM:NF039825.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF5684 domain-containing protein"
                     /protein_id="HIP6612899.1"
                     /translation="KWSFIMTEETLAQGILIGIWGTTLLFSFIWYILVAISNYILFKK
                     AGYAGWKSLIPIYNLYIQQCITFGYEKRWFILFLLIPLAGPLYGIYLVYNFGRSFGLS
                     AVQAIFYVLLTPIFNLYIAFNDGSRYQGPQEFFID"
     gene            complement(451..1365)
                     /locus_tag="AC1PIV_001924"
     CDS             complement(451..1365)
                     /locus_tag="AC1PIV_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HIP6612900.1"
                     /translation="MNELELLARALGFIFVIGLGYTLKVKGIVRREDARIFSSLVMNV
                     TLPASLLVASATTQVSIDLYLPFILGILCNLFLDMVGYWEAKKSGQQTSVGLMQLSGY
                     NIGTFTLPFVQAFFPLSSLLSVIVFDAGNAIMVLGGNYSIAAGVDEEQERMTVATFIK
                     NLSRSVPLVVYLVSLSLAVCSIKLPRELISALTIASNANPFLAMLMLGILLDLKLNWQ
                     EISRLAYLLSLRLGANILIAGVIYFLLPIDKTMKIMLLVCLVSPISVMSPIYALKLGS
                     RSAEPANVNSLSILVSLVMMVLLIFLFV"
BASE COUNT          475 a          283 c          256 g          401 t
ORIGIN      
        1 gaaatggagt tttattatga cagaagaaac attagcacag ggaattctca ttggcatttg
       61 gggtacaaca ctactatttt catttatttg gtatattctt gttgctattt ccaactacat
      121 cctcttcaaa aaagcaggct acgctggttg gaaatcattg attccaatct acaatctcta
      181 tatccaacaa tgcatcacct tcggctatga aaaaagatgg ttcattctat tcttactaat
      241 tccactagca ggaccattat atggcatcta tctcgtttac aattttggtc gtagcttcgg
      301 tttatcagct gtacaagcta tcttctatgt tcttcttaca cctatcttta acctctacat
      361 cgcctttaat gatggaagtc gttaccaagg tccacaagaa ttctttattg attaatatac
      421 aatcaagccc ccgcacacgc ggaggctttt ttaaacgaat agaaaaataa gaagaaccat
      481 catgactagg ctgaccaaaa tagataagga gttaacgttg gcaggttcag ctgagcgact
      541 acctaacttt aatgcataaa ttggggacat gactgaaatc ggagaaacta gacagaccag
      601 caacatgatt ttcatcgttt tatcaatagg tagaagaaaa taaatgactc ctgctattag
      661 aatattcgca cccagcctca aagagagaag ataggccaat cgactaattt cttgccaatt
      721 caattttaaa tcaagcaaga ttcccaacat gagcatggct aaaaaaggat tggcgttact
      781 ggctatcgtc agcgcagaga taagttcgcg tggaagtttg atagagcaga ctgctaacga
      841 taggctaact agatagacta ctagtggaac tgagcgtgaa agattcttta taaaagttgc
      901 aacggtcatt ctttcctgct cttcatccac accagctgcg atactgtaat tcccacctag
      961 aaccatgatt gcattccccg catcaaatac gatgacactt agtagactag atagcggaaa
     1021 aaaagcttgc acaaatggga gtgtaaaggt tccaatatta tagcctgata actgcataag
     1081 accgacggaa gtctgttgac cagacttctt tgcttcccag tatcctacca tatccaaaaa
     1141 aagattacaa agaatcccta atatgaaggg aaggtataaa tctatagata cttgggttgt
     1201 cgctgaagct acaaggagag aagctggtag cgtaacattc atcactaagc tagaaaagat
     1261 tcttgcatct tcccttcgaa caatcccttt gacttttaat gtataaccta aaccgataac
     1321 aaagataaaa ccgagagcac gggctaataa ttcaagttca ttcatgaaac tagtatagca
     1381 tatagaaaag aattttgatg atatataaaa atttt
//
LOCUS       DBNFCO010000146         1378 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.149, whole genome shotgun sequence.
ACCESSION   DBNFCO010000146 DBNFCO010000000
VERSION     DBNFCO010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1378)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1378)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1378
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.149"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            129..1133
                     /gene="ccpA"
                     /locus_tag="AC1PIV_001925"
     CDS             129..1133
                     /gene="ccpA"
                     /locus_tag="AC1PIV_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001228 - DNA-binding transcription
                     activator activity, RNA polymerase II-specific [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HIP6612901.1"
                     /translation="MLNTDDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLE
                     VIDRLDYRPNAVARGLASKKTTTVGVVIPNIANAYFATLAKGIDDIADMYKYNIVLAN
                     SDENDEKEINVVNTLFSKQVDGIIFMGYHLTDKIRAEFSRSRTPIVLAGTVDLEHQLP
                     SVNIDYAAASVDAVNLLAKNNKKIAFVSGPLVDDINGKVRFAGYKQGLKDNGIEFNEG
                     LVFESKYKYEEGYALAERILNAGATAAYVAEDEIAAGLLNGVSDMGIKVPEDFEIITS
                     DDSLVTKFTRPNLTSINQPLYDIGAIAMRMLTKIMHKEELENREVVLNHGIKVRKSTK
                     "
BASE COUNT          442 a          259 c          302 g          375 t
ORIGIN      
        1 aaaattgcaa gtattatcaa aaaaatagag tttatctctt gaaagtggtt tcaaaaagtg
       61 atacactata cttgagtgaa agcgtaattt tcatagaacc agaactattg aaagggagta
      121 cataacgtat gttaaacact gacgatacgg taacgattta tgacgttgcc cgcgaagcag
      181 gtgtatccat ggcgacagta tcgcgcgtgg taaatgggaa taaaaacgta aaggaaaata
      241 ctcgtaaaaa agtattagaa gtcatcgacc gcttggatta tcgtccgaat gctgttgcac
      301 gtggattggc cagcaagaag actaccactg tgggggttgt gattccaaat attgctaatg
      361 cttattttgc aaccttggcc aaaggtattg atgatattgc cgatatgtac aaatacaata
      421 tcgtcctagc aaacagtgat gaaaatgatg agaaagaaat caatgtggta aataccctat
      481 tctcaaaaca ggtggacgga atcattttca tgggctatca tttgacagac aagattcgtg
      541 cggagttttc acgctcacgt acaccgattg ttttagctgg taccgtggac ttggagcacc
      601 aattacctag cgtcaatatt gactacgctg ccgctagtgt tgatgcagtc aatctattag
      661 ctaagaacaa caagaaaatt gcctttgtat cagggccgct tgtagatgac atcaacggta
      721 aagttcgttt tgcaggctac aaacaaggct tgaaggacaa cggaatcgag tttaacgaag
      781 gattggtttt tgaatccaag tataaatacg aggaaggcta cgctctagca gaacgtattt
      841 tgaatgccgg agcaactgca gcttatgttg cagaagatga gattgctgca ggtctattga
      901 acggtgtcag tgatatgggc atcaaggttc cggaagattt tgaaatcatc acaagtgatg
      961 attccctagt gactaagttt acccgtccaa acctgacctc tatcaatcag ccactatatg
     1021 atattggtgc aattgctatg cgcatgctta ccaaaatcat gcacaaggaa gagttggaaa
     1081 accgtgaggt agttcttaac cacggaatca aagtacgtaa atcaactaag tgataaatat
     1141 gggagtagcc ggataagata tcttattact ccgccccctc actctatcaa acattataat
     1201 catttagttt atcttttatt actttgacga gcgaggaaat atttccaacc tagaacggcc
     1261 tttaggctgt tctagcaacc tgtagctatt gaggcaaact tgcttcgact tatctccagc
     1321 cttcaaaggt tcggagaacc tttgaagcga gtactaaaag caaacgaaat ggctatac
//
LOCUS       DBNFCO010000147         1368 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.150, whole genome shotgun sequence.
ACCESSION   DBNFCO010000147 DBNFCO010000000
VERSION     DBNFCO010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1368)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1368)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1368
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.150"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            86..973
                     /locus_tag="AC1PIV_001926"
     CDS             86..973
                     /locus_tag="AC1PIV_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HIP6612902.1"
                     /translation="MNNQIILLTIQVFIVALILWMLYTILSYAKKHDISLKEKFWTGF
                     GIGYVTDLLDTLGIGTFATTTTMFKLTKLVEDDRKIPATMTTAHIIPVLVEALLFITI
                     VEVDMVTLIAMAAAAFTGAFVGAKVTQKWDTKKVQRILGILLIIAACFMVYRMITNPG
                     ADLTNEVKGLTGWKLAVGIAFDFMVGMLMSMGLGNYAPELIFFSLMGISPAVALPVMM
                     LNAAMIMTAGAKQFIQSGRVNWPGVPGIVVGGVLGVLTAAFFLSNLDINNLKILVVFI
                     AAYTGFTLLRSSFVTRIKK"
     gene            985..>1368
                     /locus_tag="AC1PIV_001927"
     CDS             985..>1368
                     /locus_tag="AC1PIV_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HIP6612903.1"
                     /translation="MDIHLRNEIDLDGQIEVVDQQFQVEVKEKDGNLYLIYSNDEAEK
                     VVIKCDEEELVMTRFSTPKSIMRFISGKEAIVTIPTPLGIQHFVTDTKRYQLNRSDQS
                     VQLQYELKGLENQQLFASYDLEISWK"
BASE COUNT          398 a          227 c          308 g          435 t
ORIGIN      
        1 caaaaaaggg agataaattc ctgatttttc taaaacacaa ggatattgct atgtacccaa
       61 tggaatcttt tggtataatg gagaaatgaa taatcaaatt atcttattaa ctattcaggt
      121 ctttattgta gccctgattc tttggatgct ttacacaatt ctatcctatg ctaaaaagca
      181 cgatatttct ctaaaagaga aattttggac aggatttggt atcggttatg ttactgattt
      241 gctagacacc ttggggattg gaacctttgc aacgacaacc actatgttta aactgacaaa
      301 gttggtggaa gacgatcgta aaattcctgc gaccatgaca acggcgcaca tcataccagt
      361 cttagtagag gcgctattgt ttattacgat agttgaggtt gatatggtca ctctgattgc
      421 tatggcagca gcggcattta cgggtgcctt tgttggtgcc aaggtaactc aaaaatggga
      481 tacaaagaaa gttcaacgaa ttcttgggat tttactaatt attgcagcct gtttcatggt
      541 ctatcgcatg attactaacc ctggcgcaga tcttaccaat gaagtaaagg gcttaactgg
      601 ttggaaactg gctgttggta ttgcctttga ttttatggtg ggaatgctga tgagtatggg
      661 actgggtaac tatgctcctg agttaatttt cttctcattg atgggaatta gtccagcggt
      721 tgctcttcca gttatgatgt tgaatgctgc tatgattatg acagctggtg ccaagcagtt
      781 tatccaatca ggacgagtaa actggccagg agttccagga atcgttgtcg gtggggtgct
      841 aggtgttttg acagccgctt tcttcctatc aaatttggat attaataatt tgaaaatttt
      901 agttgtcttc attgcagcgt atacaggttt tactctgctt cgttcatcct ttgttactag
      961 gattaaaaaa tagtaggagg aactatggat attcatttac gaaatgaaat tgatctggac
     1021 gggcagattg aggtagtgga tcagcaattt caagtggaag ttaaggaaaa agatgggaat
     1081 ctctatctca tttatagtaa cgatgaagct gaaaaagttg tcataaaatg tgacgaagaa
     1141 gagttagtga tgacacgctt ttccactccg aagtctatta tgcgattcat ttctggtaaa
     1201 gaagctattg tgaccattcc tacaccgtta ggaatccagc attttgtgac cgatacaaaa
     1261 cgttaccaat taaaccgttc ggatcaaagt gtccagttgc aatatgaatt aaagggattg
     1321 gagaaccagc agctttttgc ttcctatgat ttggaaatct cgtggaaa
//
LOCUS       DBNFCO010000148         1361 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.151, whole genome shotgun sequence.
ACCESSION   DBNFCO010000148 DBNFCO010000000
VERSION     DBNFCO010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1361
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.151"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(<1..281)
                     /gene="mreD"
                     /locus_tag="AC1PIV_001928"
     CDS             complement(<1..281)
                     /gene="mreD"
                     /locus_tag="AC1PIV_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HIP6612904.1"
                     /translation="MRNKMIEIFMFPILFFILLLDGQISTLVTNWSVGLFTISSHLVL
                     MLAIFYANYVSLGFSLFIFTLLGLVYDISYLNLIGIATTTLPLVLYCIY"
     gene            complement(271..1107)
                     /gene="mreC"
                     /locus_tag="AC1PIV_001929"
     CDS             complement(271..1107)
                     /gene="mreC"
                     /locus_tag="AC1PIV_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HIP6612905.1"
                     /translation="MNKFSKLVVVVSIFLLLSFSLLFVTFSKGLQVPYLNNIVRVVVT
                     PIQSVISVPTRFFSEQKDVLTDLMNAYEENKQLKETIMSLEGMAAENTSLKEENASLR
                     SSLGVVSDFPEKQLIPGSVLVRTPSSWSEHISINIGETSGVTYNALVVANGGLVGIVS
                     SLSSDSAVVTLFTNSDEFTKLPVKISVDSKEIYGILSGYDADTNSFIINQLNSADEIA
                     VGSNVVTSDLAGETPANVQIGKVLSVKSNSNSLNREVYVEPTASFSNIYSVLVVGQTN
                     AQ"
     gene            complement(1167..1254)
                     /locus_tag="AC1PIV_001930"
     tRNA            complement(1167..1254)
                     /locus_tag="AC1PIV_001930"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1218..1220),aa:Ser,seq:gct)
     gene            complement(1267..1340)
                     /locus_tag="AC1PIV_001931"
     tRNA            complement(1267..1340)
                     /locus_tag="AC1PIV_001931"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1304..1306),aa:Ile,seq:gat)
BASE COUNT          505 a          292 c          195 g          369 t
ORIGIN      
        1 aaatagatgc aatataaaac taaaggaaga gttgtagtag caataccaat cagattaaga
       61 taactaatat catataccaa acctagcaaa gtaaatatga ataatgaaaa accaagagat
      121 acatagttag cataaaaaat agctaacata agtaccaaat gacttgaaat agtaaataat
      181 ccgaccgacc aatttgttac caacgttgaa atctgtccat caagtaataa aataaagaac
      241 aagatgggaa acatgaatat ttctatcatt ttattgcgca tttgtttgac ctaccactaa
      301 aaccgaataa atgtttgaaa aactagctgt cggctcaaca tatacttctc tatttaaact
      361 gttactattt gatttaaccg ataaaacttt accaatttgg acatttgccg gagtctcacc
      421 agccaaatca ctcgttacaa cattgctacc cactgcaatt tcatcagctg agttcaactg
      481 attaatgata aaactatttg tatctgcatc atagcccgat aaaataccat aaatttcttt
      541 agaatcaaca gaaattttca caggtaactt cgtgaattca tccgaattcg taaataaggt
      601 aacaaccgcc gaatctgaac tcaatgaact cacgatgcca actaatccac cattagcaac
      661 cacaagtgca ttatatgtca caccactagt ctcaccaata ttaattgaaa tatgctccga
      721 ccacgatgaa ggagtcctca ctaaaactga tcccggaata agttgttttt caggaaaatc
      781 agataccaca cctaaactgc tacgaagcga tgcattctct tctttcaagc tagtattttc
      841 agcagccatc ccttcaaggc tcataatagt ttcctttaat tgtttatttt cctcgtaagc
      901 gttcatcaaa tctgtcaaga catctttctg ctcagaaaaa aatctagtag gtactgaaat
      961 aaccgattga attggcgtta caacaaccct aacgatatta tttaaatatg gtacctgtaa
     1021 ccccttagag aaagtcacaa acaaaagaga aaatgacagt aataaaaaga tagaaacaac
     1081 tactactaat tttgaaaatt tattcataat atatcctcac caagatacaa taaaacgaga
     1141 atatcaagcg ataatctcgt tcactacgga gaataaggga ttcgaaccct tgcgccagtt
     1201 acccgaccta acgatttagc aaaccgtcct cttcagcctc ttgagtaatt ctccatcaat
     1261 ataatatggg cacgagtgga atcgaaccac cgacctcacg cttatcaggc gtgcgctcta
     1321 accatctgag ctacgcgccc aagataataa acttggacaa a
//
LOCUS       DBNFCO010000149         1313 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.152, whole genome shotgun sequence.
ACCESSION   DBNFCO010000149 DBNFCO010000000
VERSION     DBNFCO010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1313
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.152"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            <1..816
                     /locus_tag="AC1PIV_001932"
     CDS             <1..816
                     /locus_tag="AC1PIV_001932"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HIP6612906.1"
                     /translation="EVYAESYNKLQELDRAFPDKLKKSILQYAMQGKLVAQDPNDEPV
                     EVLLEMIRAEKQKLYEEGKLKKKDLAEIMVEKGDDNSPYGKNKENIGFSNSTLFKLPS
                     SWCYVKFGGLVLFNIGKTPPRSEPNYWGDDIPWVSISDMSNNGHIFKTKEYLSDFAIN
                     QKKVKIASAGTLLMSFKLTIGKVALEVPASHNEAIISIFPYGDKENIIRDYLMRFLPL
                     ISTTGNSKDAIKGKTLNSTSISGLLIPISNYREMKDIVTKVDLLFEKVAQLYY"
     gene            complement(770..>1313)
                     /locus_tag="AC1PIV_001933"
     CDS             complement(770..>1313)
                     /locus_tag="AC1PIV_001933"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HIP6612907.1"
                     /translation="PRNWTLLSVKDIFSITTGLSYKKTDLAIIQRGVRIIRGGNIEPL
                     AYKLLDNDYYIESKYITSESVYLKRNQLVTPVSSSLEHIGKFARIDKNYSDTVAGGFV
                     FQLTPFISSDTLSNYLLLCLSSPLFYKQLQSVTKLSGQALYNIPKTKLNDLRIALAPE
                     QEQERISNKVGQLFQKVNLL"
BASE COUNT          449 a          203 c          251 g          410 t
ORIGIN      
        1 gaagtctatg ctgaaagtta caataaactc caagagttag atagagcttt tccagataaa
       61 ctgaaaaaat ctatcctcca gtatgctatg caaggaaaat tagttgcaca agatccgaac
      121 gacgaacccg tcgaagtctt acttgaaatg attcgtgctg aaaagcaaaa actctatgaa
      181 gaaggcaagc tcaagaagaa agatttggcg gaaataatgg tcgaaaaagg agatgataac
      241 tctccttatg ggaagaacaa ggaaaatatt ggttttagta attcaacttt gtttaaactt
      301 cctagttctt ggtgctacgt taagtttggt ggtctagttt tatttaatat tggaaaaaca
      361 cctccaagaa gtgagccgaa ttattgggga gacgatattc cttgggtatc tatttcagat
      421 atgtctaaca atggtcacat cttcaaaaca aaagaatatc tatcagattt tgctattaat
      481 cagaagaagg taaagatagc ttcggcaggc accttgttga tgagttttaa gttaactatt
      541 ggtaaagtag cattagaggt ccctgctagc cataatgaag cgataatctc aatatttccg
      601 tacggagata aagaaaatat cataagagac tatctgatgc gatttttgcc cctaatctca
      661 accactggta attcaaagga tgctataaaa ggaaaaacgt taaatagtac tagtatttca
      721 ggattattga tacctatttc taactatcga gaaatgaaag atattgtaac taaagtagat
      781 ttactttttg aaaaagttgc ccaactttat tactgatacg ttcttgctct tgttcaggag
      841 ctaaggcaat acggagatca ttcaactttg tttttggaat attatataaa gcctgtccag
      901 acagcttggt tactgattgt agttgtttgt aaaaaagtgg cgatgagaga caaagtaata
      961 gatagtttga taaagtatct gacgagataa atggtgttag ttgaaataca aatcctccag
     1021 ctactgtatc tgaataattt ttatcaattc tggcgaattt tccgatatgt tctaacgatg
     1081 aagagaccgg ggttactagt tgatttcgct tcaagtaaac agattctgat gtaatatatt
     1141 ttgactcaat atagtagtca ttatctaata atttatatgc taagggttcg atatttcccc
     1201 cacgaataat ccgcacacct ctttggatga tagctaaatc tgttttctta taagataacc
     1261 ctgtcgtaat tgaaaaaata tctttgacag aaagaagagt ccaatttctc gga
//
LOCUS       DBNFCO010000150         1281 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.153, whole genome shotgun sequence.
ACCESSION   DBNFCO010000150 DBNFCO010000000
VERSION     DBNFCO010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1281
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.153"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            <1..>1281
                     /locus_tag="AC1PIV_001934"
     CDS             <1..>1281
                     /locus_tag="AC1PIV_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="InlB B-repeat-containing protein"
                     /protein_id="HIP6612908.1"
                     /translation="TGRAGVIDMPSTSGGTGVKDIFLFNNIFYFTDGEKMFVEASDAG
                     KYKDSIHFYNNAYVGVEVPDDPKAITEGITLKGVGTGPTENKSMIANAGKFLTGQLDG
                     YRLPENSSLAKLGVSKEEAISYFYKKLGVQPTIDFQDNGSLTMSPTEAFALARQTNSV
                     DAIARVYPAIEGVTYDTDFFGETLSSENLSVGAAQEKKSVFEEKISDIEISDVKTGIG
                     MRYKRSNQLADVNLSIRLINKDELQYTINANNPTFSYEIQLQKNFGEYMDLSESVTIT
                     IPIEADKKILNVLKINKNEQTESVKELPYRIENNKIILETDELGSFIIEYQMEKIKKE
                     NNTNATISESGKSSLGLQNKENSDVQAVGDKDYFSGLELSNKGEELSREDSKLMGNSI
                     NNLQTIKESESIFEGNLGRNKELSDMYQKSLPKTG"
BASE COUNT          491 a          157 c          261 g          372 t
ORIGIN      
        1 acagggagag ctggcgttat tgatatgccg agtacctcag gaggaactgg tgtaaaagat
       61 atctttttat ttaacaatat tttttacttt actgatggcg aaaaaatgtt tgtagaagca
      121 agcgatgctg gtaaatataa agatagtatt catttttata acaatgcata tgtcggagtt
      181 gaagtgccag atgatcccaa agcgataact gaaggtataa ctttaaaagg tgttggaact
      241 ggaccgactg aaaataaatc gatgattgca aatgctggga aatttttaac aggacaatta
      301 gatgggtata gattgcctga aaatagttcg ttagctaagc ttggtgtgag caaagaggaa
      361 gcaatttctt atttctataa aaaactaggt gtgcagccca caattgattt ccaagataat
      421 ggctccttaa ctatgtctcc gacagaagct tttgccttgg ctcgtcaaac aaacagtgtt
      481 gacgcgattg cacgtgttta tcctgcaata gaaggggtta cttatgatac tgatttcttt
      541 ggagaaactt tgtcgagtga aaatttatct gttggtgcag ctcaagagaa aaaatcagtt
      601 tttgaagaaa aaatctctga tatagaaatt tcagatgtga aaacagggat tggaatgaga
      661 tataaacgtt caaatcagct tgcagatgta aatttaagta taagattgat aaataaagat
      721 gaacttcaat atactataaa tgctaataat ccaacttttt catatgaaat tcaacttcaa
      781 aaaaattttg gagagtatat ggatttaagt gagagtgtga caatcaccat tccaattgag
      841 gcggataaaa agattcttaa tgttttgaaa attaataaaa atgaacaaac tgaatcagtg
      901 aaagaactgc catatcgaat tgaaaataat aaaataatat tagaaaccga tgagcttggt
      961 tcatttatca ttgaatacca gatggaaaaa attaaaaaag aaaataacac aaatgcaaca
     1021 ataagtgaaa gtggaaaaag tagtttaggg ttgcaaaata aagaaaattc agatgtgcaa
     1081 gctgtaggcg ataaagatta tttttctggt cttgaactat caaataaagg tgaagagtta
     1141 agtcgtgaag attctaaact aatggggaat tcaattaata atttacaaac aataaaagag
     1201 tctgaaagta ttttcgaagg aaatttgggt aggaataaag agttgagtga catgtatcaa
     1261 aagtcattgc caaaaacagg a
//
LOCUS       DBNFCO010000151         1238 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.154, whole genome shotgun sequence.
ACCESSION   DBNFCO010000151 DBNFCO010000000
VERSION     DBNFCO010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1238)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1238)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1238
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.154"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            122..814
                     /locus_tag="AC1PIV_001935"
     CDS             122..814
                     /locus_tag="AC1PIV_001935"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HIP6612909.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDLAFTSVLKRAIKTTNLALEAADQLWVPVEKSWRLNERHYGGLTGLNKAEAA
                     AEFGDEQVHIWRRSYDTLPPEMAKDHEHSAHTDRRYAHLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKQLSDDEIMDVEIPNFPPLVFELDE
                     NLNIVKEYYLEA"
     gene            1001..1238
                     /gene="tnpA"
                     /locus_tag="AC1PIV_001936"
                     /pseudo
     CDS             1001..1238
                     /gene="tnpA"
                     /locus_tag="AC1PIV_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011148688.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
BASE COUNT          392 a          230 c          274 g          342 t
ORIGIN      
        1 tttacatgaa agagtaatga aagcgtacac agattgtgga aaggctggca tttttttacc
       61 ttttcgtgta aaatagagaa gtataagagg ggaacctcaa aatttaaagg agaattcata
      121 aatggtaaaa ttggtttttg ctcgccatgg tgagtctgaa tggaacaaag ctaacctttt
      181 cactggttgg gctgatgttg atttgtctga aaaaggtaca caacaagcaa tcgatgcagg
      241 taaattgatc aaagaagcag gtatcgaatt tgaccttgct ttcacatctg tattgaaacg
      301 tgctatcaag actacaaact tggctcttga agctgcagat caattgtggg taccagttga
      361 aaaatcgtgg cgtttgaacg aacgtcacta cggtggtttg actggcttga acaaagctga
      421 agcagctgct gaatttggtg atgagcaagt tcacatctgg cgtcgttctt atgatacttt
      481 gccaccagaa atggctaaag atcatgagca ttcagcacac actgaccgtc gctatgcaca
      541 ccttgatgat tcagttattc cagatgcaga aaacttgaaa gtaacgcttg agcgtgccct
      601 tccattctgg gaagataaaa ttgctccagc attgaaagac ggtaaaaacg tattcgtggg
      661 tgcacacggt aactcaatcc gtgcccttgt aaaacacatc aaacaattgt ctgatgacga
      721 aatcatggat gtggaaattc caaacttccc accacttgta ttcgaattgg atgaaaactt
      781 gaacattgtg aaagagtact acttggaagc ataattcatt taaggcctga gttcgctcag
      841 gcttttttag ttatgtgact tttagtccgt cacgctccgt aaggtgcgtg acaaataaac
      901 cacccgctat gcgggtgcgc gacgaaggtt acaccaaaaa aactccaaac gcgatacaat
      961 aaaggtgttc aagcctattg taaagcgaaa ggagaaaaat atggcgcaaa aggcacatag
     1021 tttatcacat acaaagtggc tgtgttctac cacattgtct tcacacttaa gtatagacga
     1081 aaaatcatct ataatcaata tcgaagtagt ttgggagaaa tattccgacg tttgtgtact
     1141 tataaaggcg tagaaattat cgaaggacat ctgatgccgg atcatgttca tatgttagtc
     1201 agtattcctc cgcgattaag tgtatcaagc tttatggg
//
LOCUS       DBNFCO010000152         1215 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.155, whole genome shotgun sequence.
ACCESSION   DBNFCO010000152 DBNFCO010000000
VERSION     DBNFCO010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1215)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1215)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1215
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.155"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            <1..966
                     /locus_tag="AC1PIV_001937"
     CDS             <1..966
                     /locus_tag="AC1PIV_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HIP6612910.1"
                     /translation="PYVCNACPKKRSNCGYQKQFYYAKRAQLDYEVKLSDSRTGVALN
                     KEEFYRMDEIVSAAIQKGQHLNHIIASNEMSASRASIYRYLEKGYLSTKPIDFPRVVK
                     FRKRRIRNLQPIPKIAKEGRSYEDFQRFLTEKGISYWLEMDTVTGRIGGKVLLTFNLS
                     FCNFIFAQLLDNKTANEVAKHLYAIKNDLHQKEMDFCEIFPVILTDNGGEFARVDDIE
                     MDVRGESKLFFCDPNRSDQKGRIEKNHTLIRDILPKRSSFDNLTQEDINLVCSHINSV
                     KRASFNGKSAYELFTFTYGEELATLLGISKIDPENVIQSPRLLDK"
BASE COUNT          389 a          267 c          230 g          329 t
ORIGIN      
        1 ccttacgttt gtaatgcctg tccgaaaaag agaagcaact gcggatacca gaaacagttc
       61 tactacgcaa aaagagctca gcttgattat gaagttaagc tctcagattc gagaacaggt
      121 gttgcactaa acaaggaaga attctatcgc atggatgaga ttgtttctgc tgccatccaa
      181 aagggacaac acctcaacca catcatcgcc tcaaacgaaa tgtcggcatc cagagcttct
      241 atctaccgat accttgaaaa aggctatctg tccacaaagc ccattgattt cccccgtgtc
      301 gtgaaattca gaaagcggag aatcagaaac ctacaaccca ttcctaaaat cgccaaagaa
      361 ggacggtctt acgaggactt ccaacgcttt ctcacagaga aaggaatcag ctattggctg
      421 gaaatggaca ccgttactgg acggatcggc ggaaaggtac ttctcacctt taacctctcc
      481 ttctgtaact ttatcttcgc tcaattactt gataataaaa cagctaatga ggtcgctaaa
      541 catctctacg ctatcaagaa tgacctgcat cagaaagaga tggacttttg cgaaatattt
      601 cctgtcattc tgaccgataa tggcggtgaa ttcgctagag tggacgatat cgaaatggat
      661 gttcgcggag aatctaagct attcttctgt gaccccaatc gttctgacca gaaggggaga
      721 attgagaaga atcacacact tatcagagat attcttccta aaagaagttc ttttgacaac
      781 ttgacacagg aggacatcaa cctggtttgt tcgcatatca acagcgtcaa acgagcttct
      841 ttcaacggaa aatcagccta tgaactcttt acatttacct acggtgagga attggcaaca
      901 cttttgggaa tctctaaaat tgaccctgag aacgtcattc aatcacctcg attattggat
      961 aagtaatcgc tagtttttat caaaaaataa tttcaaaata gaaaggaact tgttccatcc
     1021 aaaattccag atagctagaa cttactttga gacgtctcag agccagtaac tttagtgtac
     1081 tcttttttca acattttcaa ccctaaaact cactattatc aacattttta gtcaaaaaca
     1141 gaacttagtc tgagactaaa ttctgttgat gttatgcagt tttctcagag taacttctgg
     1201 aaggacggga actag
//
LOCUS       DBNFCO010000153         1176 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.156, whole genome shotgun sequence.
ACCESSION   DBNFCO010000153 DBNFCO010000000
VERSION     DBNFCO010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1176)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1176
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.156"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            <1..320
                     /locus_tag="AC1PIV_001938"
     CDS             <1..320
                     /locus_tag="AC1PIV_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013851902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="lantibiotic ABC transporter permease"
                     /protein_id="HIP6612911.1"
                     /translation="WVLPLLYFLAKWINPYLLLATNSLICLLVAPLIAQTSVWFIFPY
                     TYHYKIAYALLHLKPSGDLEAALSGVEISTILISVSLSILVFVSFLSLLKWRITNEQN
                     SKK"
     gene            298..984
                     /locus_tag="AC1PIV_001939"
     CDS             298..984
                     /locus_tag="AC1PIV_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HIP6612912.1"
                     /translation="MNKILKSELLKLKGSLTLNLILILSIIQLFTIPLYLQFTNNSVV
                     IENIIFLPMLGYCILASIFSIFLHEQEEKANFFQNIKSEKNSGIIWGIKLISTDLLMV
                     LLGVPVWIVVGVEFNRLSYFAYVGVITWLLLVLLNHFHMLLSLIMGKGGNLVISFIEC
                     LFIIFATNKVFLNNFWLPIVLPVNMILEIGKNEIFMILVYLIGFIILSYFCNLAVMNN
                     VEIQKICKKR"
BASE COUNT          374 a          151 c          181 g          470 t
ORIGIN      
        1 cttgggtatt accactatta tattttctag caaagtggat aaatccctac ttgttgttgg
       61 ctacaaattc tcttatttgc ttattagttg ctcctctaat agctcagaca tcggtttggt
      121 tcatatttcc ttatacttat cactataaaa ttgcttatgc tcttttacat ttaaaaccct
      181 caggtgattt agaggcagca ttaagtggag ttgaaatatc gacaatttta atatcagtat
      241 ctctttcaat cttagttttt gtgagtttcc ttagtttgtt gaagtggagg ataactaatg
      301 aacaaaattc taaaaagtga gttgctaaag ttgaaaggct ctcttacttt aaatcttatt
      361 ttaattttat caattattca attattcaca attcctcttt atttacagtt tacaaataat
      421 tcagttgtaa ttgaaaatat cattttttta cctatgttag gatattgtat attagcatca
      481 attttctcta tttttcttca tgaacaagag gaaaaagcaa atttctttca aaatattaaa
      541 agcgaaaaaa atagtggaat tatttgggga ataaagctta tttcgacaga cttacttatg
      601 gttttattgg gagttccagt ttggatagtg gtaggagttg aatttaatag actctcttac
      661 tttgcgtatg ttggtgtgat tacttggtta ttattagtct tacttaacca tttccatatg
      721 ttacttagtc ttatcatggg aaagggaggg aatctagtaa tttcttttat cgaatgtctg
      781 tttattatat ttgcaaccaa taaagtattt ttaaataact tctggttgcc tatcgtttta
      841 cctgttaata tgatcctaga aattgggaaa aatgaaattt ttatgattct agtatactta
      901 attggtttta tcatattatc gtatttttgt aatttagctg ttatgaataa tgttgaaatt
      961 caaaaaatat gtaaaaagag gtaaattggt tagaggtcac taaaagagta gaatacaaca
     1021 aaattcaata gataaaaagc gaatgacagc atattttgaa atctaaagat tgcagatcat
     1081 ccgcttttta tgtctatttt attatctttt caagacagta ttgttcatga tattttaaaa
     1141 atatcagact ttttcagcag tttcattggt caacta
//
LOCUS       DBNFCO010000154         1173 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.157, whole genome shotgun sequence.
ACCESSION   DBNFCO010000154 DBNFCO010000000
VERSION     DBNFCO010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1173
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.157"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            <1..>1173
                     /locus_tag="AC1PIV_001940"
     CDS             <1..>1173
                     /locus_tag="AC1PIV_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612913.1"
                     /translation="EYKSLSDAFQNGQRNDYENSMLYSKICFNYLDRGRIEDFSHTKV
                     EADDSKEREKQKLKAQKIQGLILSMNEEYRMAFMLYQLFYTDRTQWDENLAFYDNNIQ
                     SIMKHGKQYHGYLFDQVKNIILSETDIDHRITESFLDKIWETKNETIMDFSWFDQFGD
                     QHQMSNFKILYVQWILSGATTSYLKSRINFERGFPIKVRNSLVGKIKGKENRKMSVKD
                     LKWRIRRKEERIGHLCRDYLLLTDQLTTIFTKVPSDKHNLQISVEYLLHSGKVNLSDV
                     IDNISVTSLLRLEWLLRWNYYHYHRESNYTSRTFFDEMTSNDRYYWSAGRGILEFFIA
                     KIVDNFYRDLYQDKEFMAGFKYHLESQLNSLNKTVEEYVELIAERVSGIDNLSILQ"
BASE COUNT          436 a          137 c          219 g          381 t
ORIGIN      
        1 cagaatataa aagtctatcc gatgcgtttc aaaatggcca gcgaaatgat tatgaaaaca
       61 gtatgcttta ttctaaaatt tgtttcaatt atttagatag aggaagaatt gaagatttta
      121 gtcatacaaa agttgaagca gatgatagta aagagcggga aaaacaaaaa ttaaaagctc
      181 aaaaaataca gggattgatt ctgagcatga atgaagaata ccgaatggca tttatgctat
      241 atcaattatt ttatacggat cgtactcaat gggatgagaa tctggcattt tacgataata
      301 atattcaaag tataatgaag catggtaagc aataccatgg ttatttattc gatcaagtga
      361 aaaatattat tctaagtgag actgatattg atcatcgtat tacagaatct tttttagaca
      421 agatatggga aacaaaaaat gaaacaatta tggatttttc atggtttgat caatttgggg
      481 atcaacatca gatgtcgaat tttaaaattc tttacgtaca atggatatta tcaggagcga
      541 caacttccta tttgaagagt agaattaatt ttgaaagagg gtttcctatt aaagtacgca
      601 attcacttgt tggaaaaata aaaggaaaag aaaataggaa gatgtcagtt aaagatttga
      661 aatggaggat tagacgtaaa gaagaaagga ttggtcatct ttgccgagac tatctattat
      721 taacagatca gttaacgact atttttacaa aagtaccatc tgataaacat aatttacaaa
      781 tatcagttga atatcttttg cacagtggta aagtgaattt atcggatgtt atagataata
      841 tatcagtaac aagtttactt cgcttggaat ggcttttgag atggaactat tatcattatc
      901 atagggagtc aaattatact agcagaacat tctttgacga aatgacctct aatgaccgat
      961 attattggtc tgctggacgt ggtattttag aatttttcat tgccaaaatt gttgacaatt
     1021 tttatcgtga tttataccaa gataaagagt ttatggctgg ttttaaatat catttagagt
     1081 cacaattaaa ttcattaaat aaaacagttg aagagtatgt ggagttgatt gctgaaagag
     1141 tttctggaat tgataatctt tcaattctac aga
//
LOCUS       DBNFCO010000155         1139 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.158, whole genome shotgun sequence.
ACCESSION   DBNFCO010000155 DBNFCO010000000
VERSION     DBNFCO010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1139)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1139)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1139
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.158"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            90..425
                     /locus_tag="AC1PIV_001941"
     CDS             90..425
                     /locus_tag="AC1PIV_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SSU0592/SSU0593 family protein"
                     /protein_id="HIP6612914.1"
                     /translation="MKRIVTKRSYKVGLCAMALALLMSTAGGVTAGAQGHNFTSSDSS
                     AMRNTQVLVKGNTSNRSSHDGPVKIAMPRAAGSKKQKTWYESLWSTIKKFFEQLRHGF
                     HLERLFKNG"
     gene            535..879
                     /locus_tag="AC1PIV_001942"
     CDS             535..879
                     /locus_tag="AC1PIV_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612915.1"
                     /translation="MKQANSKLVALTLITTLAVTSVIATTVHAEEKVTADQTVAGKHK
                     PITGEQLQKAIGDRNPNSIQIQAKFENTNFKNQGITFIGKAEIPSKSSEKSSWFWELW
                     TRFTTFVKGIFS"
BASE COUNT          388 a          162 c          216 g          373 t
ORIGIN      
        1 aagttgggat ttacgttatt tttttgtgat atactggcac tacattgtct aaaaaagggc
       61 gaatattgta taaaggagat atttcaaaaa tgaaacgtat tgtaacaaaa cgtagttata
      121 aagttggtct gtgtgctatg gctcttgctc tgttgatgag cactgcaggt ggcgtaactg
      181 ctggtgcaca ggggcataat tttacttcat cagatagctc tgcaatgaga aatactcagg
      241 tgcttgttaa gggaaataca tcaaatcgga gttctcatga tggtccagta aaaattgcga
      301 tgccgagagc tgctggttct aaaaaacaaa aaacttggta tgaatctctt tggagtacca
      361 ttaaaaagtt ttttgaacaa cttcgtcatg gttttcattt agaaagactg tttaaaaatg
      421 gatagtaatt cagttttgat ttattaatct attaataatc ttataacatt tagcgcaatt
      481 aatttataaa ccttcatatt aaaaaaacta atactttgta aaaggagaca tttcatgaaa
      541 caagctaatt caaaactagt agctttaaca ctcattacaa ctctcgcagt tacctctgtg
      601 attgcgacaa cggtgcatgc tgaagagaaa gtaactgctg atcagactgt agcaggaaaa
      661 cacaaaccga ttacgggtga gcagcttcaa aaagcgattg gagatagaaa tccaaatagt
      721 attcagatac aagctaaatt tgaaaatacc aatttcaaaa atcaaggaat aacttttatt
      781 ggaaaagctg aaattccatc taaatcttct gaaaagtctt catggttttg ggaactttgg
      841 actcgtttta caacttttgt caaaggtatt tttagctaag gtttctattt ttcgttgact
      901 tcatatggat agagaacagt ggttcatgtg agcttttatt caaatgaaaa gcgtatgaaa
      961 tattggagag atctaggcat ctaaactaga gattgtgcaa gaaattatgt aatagacctc
     1021 acattttttg cgaatgagat gttgacacga attccatatt tcttgagtct cagttgtaat
     1081 ttttcttaga taaattaaag agtgaaaagt ttaggatgta attgttctaa actttttat
//
LOCUS       DBNFCO010000156         1077 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.159, whole genome shotgun sequence.
ACCESSION   DBNFCO010000156 DBNFCO010000000
VERSION     DBNFCO010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1077)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1077)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1077
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.159"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            <1..699
                     /locus_tag="AC1PIV_001943"
     CDS             <1..699
                     /locus_tag="AC1PIV_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000452012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIP6612916.1"
                     /translation="EVIIQNLRKSYKDKEVLKDVSFKIEEGTICGLLGVNGAGKSTIM
                     KILFGLERADSGEVIFNGKHKDIVEENRFDIGALIESPAIYLNLSAFDNLKTRALLHD
                     IPDERIYEVLQLVGLSDTGKKKAGHFSLGMKQRLGLGMAIITNPDLLILDEPTNGLDP
                     DGIKELLNLIRDLKKSGMTVLLSSHQLSEVSKIADQIVILNQGKIFYDDINKNSNDLE
                     KLFFRIVHGGDGND"
     gene            692..>1077
                     /locus_tag="AC1PIV_001944"
     CDS             692..>1077
                     /locus_tag="AC1PIV_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013851902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic ABC transporter permease"
                     /protein_id="HIP6612917.1"
                     /translation="MTNIFKSEWLKQKSSSDKKLLILIPLLAIFIAFILAGPLNLESF
                     SIYWWEGGFLFTLLGLLFLADYSAEENAGAFQNISLGRYTFTIYLAKILLKFKDVLIS
                     TFIFTIIFYGISFLFSGVISVDIGKD"
BASE COUNT          354 a          138 c          218 g          367 t
ORIGIN      
        1 gaagttatca ttcaaaatct aagaaaaagc tataaagaca aagaggtttt aaaagacgtt
       61 tcatttaaaa ttgaagaagg tactatttgt ggtcttctgg gagtaaatgg ggctgggaaa
      121 tccaccatta tgaaaattct ttttgggtta gaaagagctg atagtggaga agtcattttc
      181 aatggaaagc ataaggatat tgtagaagaa aatagatttg atattggagc gttgatagaa
      241 tctcctgcta tctatttgaa tctttctgca tttgacaatt taaaaacacg agcattgcta
      301 catgatattc cagatgaaag aatttatgag gtacttcagt tggttggttt atctgatact
      361 ggaaaaaaga aggcagggca cttttcatta ggaatgaagc aacgacttgg tttaggaatg
      421 gcaattatta ccaatcctga tttattaatt ttagatgagc caactaatgg tctagatcca
      481 gatgggataa aagaattgct aaatttaatt agggatctaa aaaaatctgg aatgacagtc
      541 ctcttgtcca gccatcaact aagtgaagtc agcaaaattg cggatcaaat cgttatactg
      601 aatcagggca agatttttta cgatgatatt aataagaatt caaatgattt agaaaaacta
      661 ttctttagaa ttgtccatgg aggtgatgga aatgactaat atttttaaat ctgagtggct
      721 gaagcaaaaa tctagttctg ataaaaaatt actaatcctt attcctttgc tagcaatttt
      781 tatagctttc atactagcag gacctctcaa tttagaaagt ttttcaattt attggtggga
      841 gggaggattc cttttcactc tccttgggtt attgttttta gctgattata gcgcggagga
      901 gaatgcaggt gcgtttcaaa atattagctt gggtagatat acgtttacta tttatttagc
      961 gaagatactg ttgaagttca aggatgtttt gatttcaacc tttattttta cgataatatt
     1021 ttatggcatc tcatttcttt tttcaggtgt gatatcagta gacattggta aagattt
//
LOCUS       DBNFCO010000157         1074 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.160, whole genome shotgun sequence.
ACCESSION   DBNFCO010000157 DBNFCO010000000
VERSION     DBNFCO010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1074
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.160"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            205..1068
                     /locus_tag="AC1PIV_001945"
     CDS             205..1068
                     /locus_tag="AC1PIV_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIP6612918.1"
                     /translation="MSCFGKTLKFIREGKGKSLAEVAKGHISTSQLSRFENGESDITV
                     SKLFGVLAEMNVDVDEFVYASQDFKKDELTRILEQLKQSIYIRDVVTIKKILSEQLAK
                     AERDSRREFHRLNAILIAYKLRNLDKTIVVSKEDTAFLTDYLFRVENWSYYEILLFAN
                     TIDKLGHQTMMLFCRELIHRTQFYREMKQHRLVVSQVLLSAYLVSVQTKELVDAIFLE
                     KTIEGLLFDETEIFERILFKFGKAFYDYQNTGTSNAILEMRKCIGLLRAVDSQNIADW
                     YESILEKILIE"
BASE COUNT          355 a          139 c          224 g          356 t
ORIGIN      
        1 attattttat aacaatgatt ggtggaatgt cttttaggat actaataagt aaaattaaaa
       61 cgatagtaat gtttgcaatt agataatttt gtttcattga tattccccat tgttgaatat
      121 agataatatt tattttaaaa tcatgataac atctattaag ttatgcttta aacaaatccc
      181 ttatatacaa aaggaggtct ggaaatgagt tgttttggga aaacgttgaa atttatcaga
      241 gagggaaagg ggaagagttt ggcggaggtc gccaagggac atatttctac ttctcaactt
      301 tctcggtttg aaaatgggga atccgacatt actgttagta aattatttgg tgtgctggca
      361 gaaatgaatg tggatgtgga cgagttcgtg tatgccagtc aggatttcaa aaaagatgag
      421 ctgactagaa ttttggaaca actaaaacaa tccatctata tcagagatgt tgtaaccata
      481 aagaaaatct tgtctgaaca attagcaaaa gcagaaagag attctcgtag ggagtttcat
      541 cggttgaatg ctattttaat cgcttataaa ctgagaaact tagataagac aatagttgtt
      601 tcgaaagaag atacagcctt tttaacggat tacttatttc gagttgagaa ttggagctac
      661 tatgagatct tactatttgc gaatacgatt gacaaattgg gtcatcaaac aatgatgctt
      721 ttttgtagag agttaattca tcgtacacag ttttaccgtg aaatgaaaca acatcgattg
      781 gtagtttctc aagttctcct tagtgcttat ctagtcagcg ttcaaactaa ggaacttgtc
      841 gacgcaatct ttcttgaaaa gactatcgaa ggtttgcttt tcgacgagac agaaattttt
      901 gaacgcattt tgtttaaatt tggtaaggct ttttatgatt atcaaaatac cggaacttct
      961 aatgctattt tggagatgag aaagtgtatt ggacttttac gagcggtcga tagccagaat
     1021 atagcagatt ggtatgaaag tatattggaa aagatactta ttgagtagtg gttg
//
LOCUS       DBNFCO010000158         1009 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.161, whole genome shotgun sequence.
ACCESSION   DBNFCO010000158 DBNFCO010000000
VERSION     DBNFCO010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1009)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1009)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1009
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.161"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            3..299
                     /locus_tag="AC1PIV_001946"
     CDS             3..299
                     /locus_tag="AC1PIV_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612919.1"
                     /translation="MILIVLIISYSIYRRCHPNNMDTKQALKCPKCKSIKLQTYIPTQ
                     KRYSRKAGMIGHAINGIEGAMFAMLYEADRTYYRCQHCGYRFSRKENRFISNIE"
     gene            complement(667..>1009)
                     /locus_tag="AC1PIV_001947"
     CDS             complement(667..>1009)
                     /locus_tag="AC1PIV_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612920.1"
                     /translation="TYESLFYRVVFGITKIFDVREKNGIFKILSKLRHSTKDRSLLSI
                     LSTIQEGIDKEQKNIDEIKLLRDKLLAHLDKEMVFSTERLDIGILYYYFEAIEIKSIY
                     TACIELYNAFI"
BASE COUNT          366 a          176 c          134 g          333 t
ORIGIN      
        1 cgattatcct catagtacta ataatctctt atagcatcta tcgcagatgc catcctaata
       61 atatggacac taaacaagcg ctcaaatgtc caaaatgtaa gtcaataaaa ctgcaaactt
      121 acattccaac acaaaaaaga tattctcgta aagccggtat gattggtcat gcaatcaatg
      181 gcatagaggg agctatgttt gcaatgctct atgaagctga tcggacttat tatcgttgtc
      241 aacattgcgg ttaccgattt tctagaaagg agaatcgttt tatttccaac atcgaataac
      301 ctccctgatt tttagagaat tttgctattg aaaacgaaga attctcaccc cttacaaatc
      361 ccgttatatc aacatttacg aaaatgaaac ttccatgaaa atggactaaa atcctctgat
      421 ttggataaaa tcgacaccaa ttaacaccat aaaatagact agtcatcagt aggtcaaact
      481 aatttgacct actttatctt atagatggat aatttattaa tcaaattcaa aatgataggt
      541 caagtatttt ataaatttat cgatataaga agacaaaaaa aactaatcaa tacgagttat
      601 tcttcaagaa aaaatctttt caaaattatt tctcttttag gaagttcgac ttgttgctga
      661 ttatctctat ataaaagcat tatataactc gatacaagcc gtatatatgg acttaatttc
      721 tatagcctca aaataatagt atagaatacc aatgtctaat ctttctgttg aaaagaccat
      781 ctctttatct aagtgagcca agagtttgtc gcgaagcaat ttgatttcat caatattttt
      841 ttgttcttta tcaataccct cttgaatggt actcaaaatt gataaaagag atctatcttt
      901 ggtactatgt ctcaacttag atagaatctt aaaaatacca tttttttctc tgacatcaaa
      961 aattttagtt ataccgaaga caactctata aaataaagat tcatatgtt
//
LOCUS       DBNFCO010000159          997 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.162, whole genome shotgun sequence.
ACCESSION   DBNFCO010000159 DBNFCO010000000
VERSION     DBNFCO010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 997)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 997)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..997
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.162"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(<1..995)
                     /gene="wzy"
                     /locus_tag="AC1PIV_001948"
     CDS             complement(<1..995)
                     /gene="wzy"
                     /locus_tag="AC1PIV_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009909570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide repeat unit polymerase Wzy"
                     /protein_id="HIP6612921.1"
                     /translation="MSNSQVVLAIGKASVIQYLSYLVLILCIVNDLLKNNKHIVVYKL
                     GYLFLIIFLFTIGICQQILPITTKIYLSISMMIISVLATLPISLIKDIDDFRRISNHL
                     LFALFITSILGIMMGATMFTGAVEGIGFSQGFNGGLTHKNFFGITILMGFVLTYLAYK
                     YGSYKRTDRFILGLELFLILISNTRSVYLILLLFLFLVNLDKIKIEQRQWSTLKYISM
                     LFCAIFLYYFFGFLITHSDSYAHRVNGLINFFEYYRNDWFHLMFGAADLAYGDLTLDY
                     AIRVRRVLGWNGTLEMPLLSIMLKNGFIGLVGYGIVLYKLYRNVRILKTDNIKTIG"
BASE COUNT          401 a          179 c          112 g          305 t
ORIGIN      
        1 cctattgttt ttatattatc tgtttttaat attcttacat tacgataaag tttatataaa
       61 acaatcccat accctaccag accgataaaa ccatttttta acataatact cagtaagggc
      121 atttcaagcg ttccattcca acctaaaacg cgtctaaccc ttatagcata gtctaaagtt
      181 aaatccccat atgccaaatc cgctgcacca aacattagat ggaaccaatc atttctataa
      241 tactcaaaaa aattaataag accattaacg cgatgagcgt aagaatcact atgtgttatt
      301 aaaaaaccaa agaaatagta taaaaaaata gcacaaaata gcatggaaat atatttaagc
      361 gtactccatt gtctttgttc tattttgatt ttgtcaagat taacaagaaa tagaaaaagc
      421 aatagtatta aataaactga gcgtgtgttt gaaataagaa tcaaaaacaa ttctaatcct
      481 aaaataaaac gatccgttct tttataggaa ccatacttat acgccaagta agttaatacg
      541 aaccccatta aaatagttat tccaaaaaag ttcttatgcg tcaatcctcc attaaaaccc
      601 tgactaaaac cgataccttc tactgccccc gtgaacatcg ttgcccccat cattattcct
      661 aatatcgaag ttataaaaag agcgaataac aaatgatttg aaatccgtct aaaatcatca
      721 atatctttta tcaaacttat tggcaacgtt gctaaaactg aaataatcat cattgaaatt
      781 gataaatata ttttagttgt tataggaaga atttgctgac atattccgat agtaaataaa
      841 aatataataa gaaacaaata ccctaattta taaactacaa tatgtttgtt attttttaat
      901 aaatcattaa ctatacataa aatcaaaact aaataagata gatactgaat cacagaagct
      961 ttgcctatcg ctagaacaac ttgcgaatta ctaataa
//
LOCUS       DBNFCO010000160          971 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.163, whole genome shotgun sequence.
ACCESSION   DBNFCO010000160 DBNFCO010000000
VERSION     DBNFCO010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 971)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 971)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..971
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.163"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            <1..>971
                     /locus_tag="AC1PIV_001949"
     CDS             <1..>971
                     /locus_tag="AC1PIV_001949"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HIP6612922.1"
                     /translation="ITYLYGDKVYTNTNLDFWGNQWDMQKSISTGSKFQHKSSGKATI
                     GVIDSGITYDNPDIYSHIISVQNFTSDLETGIVDNQNVVDKIGHGTSVVGQISSSGEY
                     LGIAPDMKIRMYRVFDEGNAQDQWILKALIQAAKDDVDVINLSLGEYLLRDSTDEDDD
                     TALINIYQRAINYAHNQGSVVVASVGDEGMDLQNQDELKNYLGSLRGKDYSQVDGTVQ
                     DIPAELDNVVTVGSVDDNDLVSSFSNQGNGDIDIYATGGGSQALSKVGYDKWVADKLY
                     EKEWILVPTLEGKYTYAYGTSISTPKVSAALGLIIEKYNLKDQPDEA"
BASE COUNT          337 a          124 c          209 g          301 t
ORIGIN      
        1 atattactta tttgtatggg gacaaggttt atacaaatac taatttagat ttttggggaa
       61 atcagtggga tatgcaaaag agtattagta ctggaagtaa atttcaacat aagtcttctg
      121 gtaaagcaac aattggtgta atagattctg gtattacata tgataatcca gatatttatt
      181 cacacattat ttcagtacaa aatttcacat cagatttgga aacaggaata gttgataacc
      241 aaaatgttgt agataaaatt ggccatggga cctctgttgt gggacaaatt tcatcaagtg
      301 gagaatattt agggatagca cctgacatga aaatacgaat gtatcgtgtt tttgatgaag
      361 ggaatgctca agaccaatgg attctcaaag cgctcattca agcagcaaaa gatgatgttg
      421 atgttattaa ccttagttta ggagaatatt tgttaagaga ttccactgat gaagatgatg
      481 atacagcttt gatcaatatc tatcaacggg caattaatta tgctcataat caaggttccg
      541 ttgtcgttgc ttcagtaggt gatgaaggga tggatttaca gaatcaagat gaattaaaaa
      601 actatcttgg tagtttaaga ggaaaagatt atagtcaagt tgatggaact gtacaagata
      661 ttccggctga attagacaat gttgttacag ttggttcagt agatgataat gatcttgtat
      721 ctagtttctc aaatcaaggg aatggcgaca ttgatatcta tgcaacagga ggtggaagtc
      781 aagcgctttc taaagtagga tatgataaat gggtagctga taaattatat gaaaaagaat
      841 ggattcttgt tccaacgctt gaaggaaagt atacatatgc atatgggact tcaatttcga
      901 ctcctaaagt ctctgcagct ttaggattga ttatagaaaa gtataatttg aaggaccaac
      961 cagatgaagc t
//
LOCUS       DBNFCO010000161          932 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.164, whole genome shotgun sequence.
ACCESSION   DBNFCO010000161 DBNFCO010000000
VERSION     DBNFCO010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 932)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 932)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..932
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.164"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            <1..204
                     /locus_tag="AC1PIV_001950"
     CDS             <1..204
                     /locus_tag="AC1PIV_001950"
                     /inference="COORDINATES: protein motif:HMM:TIGR03731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_process: GO:0042742 - defense response to bacterium
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gallidermin/nisin family lantibiotic"
                     /protein_id="HIP6612923.1"
                     /translation="FEQRKNNWRNFIMNNEDFNLDLVTISKENNSGASPRVTSKSLCT
                     PGCKTGILMTCAIKTATCGCHFG"
     gene            445..932
                     /locus_tag="AC1PIV_001951"
                     /pseudo
     CDS             445..932
                     /locus_tag="AC1PIV_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400478.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic dehydratase"
BASE COUNT          344 a          115 c          159 g          314 t
ORIGIN      
        1 ttcgaacaaa gaaaaaataa ttggaggaat tttattatga acaatgaaga ttttaatttg
       61 gatcttgtca caatctcaaa ggaaaacaac tcaggagctt cacctcgggt aactagtaaa
      121 tcattatgta ctcctggatg taagacgggt attttgatga cctgtgcaat caaaactgca
      181 acttgtggtt gccattttgg ataaaattta tttgtttagt aactatcttt ttgcaaatct
      241 tgactaagaa agaaagggac tctatatctt ttcgagtaag gtccctctaa atattagaat
      301 atttgtttag gatattactc tttagacgaa tatgtctatt gctaaaataa aggtagtgga
      361 tagtagtcta ctacctttat ttttataaat ttccaaaata atatttgaag atttataaaa
      421 ataatttaga agttggagct gctaatggaa cataaatata ctacaaataa ttttttggtt
      481 cgtaatgcaa tcattggaat acatgaattg taggaatgtg attataattc atttttagaa
      541 actataagag agaataagat attccaggag caactatttg tagccagcag gagtttatat
      601 gaatcgcttc aaaaatatta tagtggtgat tcaatgaaaa ggaaaaaaat caaccaatta
      661 tcagaatctg tatataaata ttataagcgt agtaaggagc gctcaacacc atttggttta
      721 tttagtgaaa cttcaatagg ttcattttct tctacagaga aattaaactt gaatggaaaa
      781 acattaaaaa aagtactctt ggattcagag tggttaatac gtctagtttt taagattgag
      841 aaggaatatt ctcgagaatt agcctataaa ataaatccag ccaactatca atttggagat
      901 agagttgttc aattgttttc tataaatgat ac
//
LOCUS       DBNFCO010000162          915 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.165, whole genome shotgun sequence.
ACCESSION   DBNFCO010000162 DBNFCO010000000
VERSION     DBNFCO010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..915
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.165"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            25..789
                     /locus_tag="AC1PIV_001952"
     CDS             25..789
                     /locus_tag="AC1PIV_001952"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamic
                     endopeptidase"
                     /protein_id="HIP6612924.1"
                     /translation="MKRLLRRIRPTKPLKELTWIDLIIITTILCGNAIYTSTMQWIAS
                     FSATETVETGVLSFSPADNWWALANQGKLFLFALVYLLIRNYDFKQLKVKLEWTVLLW
                     GPLIFIGAGLISDLTFTAFSYIPGLSGGYNFLGYLPYYDWNIMTVLNRFLAVDYSTVI
                     YSLFNGFYEEFFFLGLLLSTDKKKRSLVLLFSTIVRISFHTYQGMVSALVIGVAFGLF
                     YYYMYTRKNDNLLPYFLGHALADMVGTSFFSLFIAG"
BASE COUNT          260 a          171 c          175 g          309 t
ORIGIN      
        1 atacaaaaat ataaggagga aaaagtgaaa agattactga gacgcattcg tccaacaaag
       61 cccctaaaag aactcacttg gatagatttg attattatca caacgatttt atgtggtaat
      121 gctatttata cctcaaccat gcaatggata gcatcatttt ctgcaacaga aaccgttgaa
      181 acaggagttc tgtcgtttag tccagccgat aattggtggg ctctagccaa tcaaggaaaa
      241 ttattcctgt ttgccctggt gtatttattg attcggaatt atgatttcaa gcagctaaaa
      301 gtaaaattag aatggaccgt tctactctgg ggaccactga ttttcattgg tgcgggcctg
      361 attagcgatt tgacatttac agctttttca tatattccag gtctgtctgg tgggtataat
      421 ttcctcggat acttgcctta ctatgactgg aatatcatga cagtgctcaa ccgtttccta
      481 gccgttgact acagcacagt tatctattcc ttgtttaatg gcttctatga agagttcttt
      541 ttcttaggat tattgttgag cacagataag aaaaagcgtt cgctggtctt actcttttca
      601 acaattgtcc gtatatcttt ccatacctat caaggaatgg tatctgctct tgttattggt
      661 gtagccttcg gccttttcta ttactacatg tacacaagga aaaatgacaa tttattgcca
      721 tatttcttag gacatgctct tgcggatatg gttggtacaa gtttcttctc attatttatt
      781 gcagggtaaa caatgagaag aacggacatc aagctaatcg gataaaattt ctttctccct
      841 acagctgaca aacggatgat gatacgtagt ttctattaac ttggtatcat cacccgtttt
      901 attgtgctga tatat
//
LOCUS       DBNFCO010000163          912 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.167, whole genome shotgun sequence.
ACCESSION   DBNFCO010000163 DBNFCO010000000
VERSION     DBNFCO010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 912)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 912)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..912
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.167"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            <1..371
                     /locus_tag="AC1PIV_001953"
     CDS             <1..371
                     /locus_tag="AC1PIV_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HIP6612925.1"
                     /translation="QDWAVRYPQNILIAVMDDKVVGFACYGSSSQEDLQGVGELYALY
                     VLADYYNQKIGYQLMQAALEKLQSYETVILWVLEGNARAIAFYEKVGFRFDGVKKTVN
                     LGAERTEYRMIFKQKERENG"
     gene            364..831
                     /locus_tag="AC1PIV_001954"
     CDS             364..831
                     /locus_tag="AC1PIV_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HIP6612926.1"
                     /translation="MARKEMVTLTNMCLIEDKEGKVVVQIRDPKRYRWSGVAFPGGHI
                     EEGENFHDSVVREVQEETGLTVTDARLVGLKHWPDKEGHRYIVFLYKATEFTGTIRST
                     EEGEVRWVEKSELPQMDLAYDLLEILKVMDEPDLSEFFYTRKNDDGEWDKNFR"
BASE COUNT          280 a          141 c          241 g          250 t
ORIGIN      
        1 gtcaagactg ggcagttcgg tatcctcaga atatcttgat agctgtgatg gatgataagg
       61 tcgttggctt tgcctgttac ggctcatcta gtcaggagga tttgcaaggg gtaggggagc
      121 tctacgccct ctatgtcttg gcggactatt ataatcagaa gataggctac cagctcatgc
      181 aggcagcttt agaaaaattg cagagctacg aaaccgttat tctctgggta ttggagggga
      241 atgcgcgtgc cattgccttc tatgaaaaag tgggcttccg atttgatggt gtcaaaaaaa
      301 cggtcaattt aggtgcagaa cgtacagaat atagaatgat ttttaaacag aaagagagag
      361 aaaatggcta gaaaagaaat ggtcactttg actaacatgt gtctaatcga agataaggaa
      421 gggaaggtcg ttgtacagat tcgagatccc aagcgttatc gttggtctgg tgttgccttt
      481 ccaggtggac atattgaaga aggcgagaat ttccatgatt cggttgttag agaagtgcaa
      541 gaagaaacag gtttaacagt cactgatgct cgcttggttg gtcttaaaca ttggccggat
      601 aaggaagggc atcgttacat tgtatttctc tataaggcaa cagagtttac aggaactatc
      661 cgatcaactg aagaaggcga ggtgcgttgg gttgagaagt cggaactgcc tcagatggat
      721 ttggcctatg acttactaga aatcctgaaa gtcatggatg agccagattt gtccgagttc
      781 ttttatacta gaaaaaatga cgatggagag tgggacaaga attttaggta gaagctagga
      841 atagcttctt ttttatgttg tttgaataaa aatacaacaa atgagttgac aaatgtataa
      901 aaatgacata aa
//
LOCUS       DBNFCO010000164          903 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.168, whole genome shotgun sequence.
ACCESSION   DBNFCO010000164 DBNFCO010000000
VERSION     DBNFCO010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 903)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 903)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..903
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.168"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(<1..223)
                     /locus_tag="AC1PIV_001955"
     CDS             complement(<1..223)
                     /locus_tag="AC1PIV_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014638884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HIP6612927.1"
                     /translation="MKLIKLNHAVRVRFNPYIITSKRLFLSRVGMDLFLGMLLINTWV
                     SPYSIPIKSVLSLIFIGIICSIEKFFKSVF"
     gene            complement(180..416)
                     /locus_tag="AC1PIV_001956"
     CDS             complement(180..416)
                     /locus_tag="AC1PIV_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012774901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612928.1"
                     /translation="MKIYKFMFNITYPALVISLYIIFQMKGTMSPWFDTLFVAGGFLV
                     IPLLLLLLGYLSENDHGGTDNEANQAESCSTSEV"
     gene            complement(471..791)
                     /locus_tag="AC1PIV_001957"
     CDS             complement(471..791)
                     /locus_tag="AC1PIV_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612929.1"
                     /translation="MKTFKDIFLSEGMEMPNINGIKRVQSFNSDKSVNFTLDDESRDF
                     LKENLPIEGVIYEPTLKKLAENIIILNRQKHRISDEFRISLMNKEIYQGYRETSFYTS
                     IIEA"
BASE COUNT          307 a          160 c          124 g          312 t
ORIGIN      
        1 taaaaacaga cttaaaaaat ttttcaatag aacaaattat tccaataaat atcaatgaaa
       61 gcactgattt aatagggatt gagtatggag aaacccaagt gtttatcaat aacattccta
      121 aaaataaatc cattccgact ctgctcaaaa acaatctttt agaggttatt atataaggat
      181 taaacctcac tcgtactgca tgattcagct tgattagctt cattatctgt ccctccgtgg
      241 tcattttctg ataaataacc caacaataac aataaaagtg gaataactaa aaaacctcca
      301 gctacaaaca aagtatcaaa ccacggagac atcgtccctt tcatctggaa tataatatac
      361 aaagaaataa ctagagcagg ataggttatg ttgaacataa atttataaat tttcataata
      421 atttcctttc ataaaaccaa agggggaggg gttagctccc ccttatatca ctaagcctca
      481 attattgagg tgtaaaaaga agtttccctg tagccttggt aaatctcttt gttcatcaag
      541 ctaatcctaa attcatcaga aatacggtgt ttttgacgat taagaataat gatgttttct
      601 gctaacttct tcaaagtagg ctcatagatt accccttcaa ttggcaaatt ttcctttaaa
      661 aaatctctgg attcatcatc taaggtaaag tttactgatt tgtctgaatt aaagctctgt
      721 actcgcttaa ttccattgat atttggcatt tccattcctt cgctaaggaa aatatcttta
      781 aatgttttca tctatttatt tctccatttt ttattttgtt gttacagtca atattcttaa
      841 ataaattggt gaagctctag ccttcattag tattctcctc tttgtgttta tgtataaatg
      901 tag
//
LOCUS       DBNFCO010000165          882 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.169, whole genome shotgun sequence.
ACCESSION   DBNFCO010000165 DBNFCO010000000
VERSION     DBNFCO010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 882)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 882)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..882
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.169"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(<1..844)
                     /locus_tag="AC1PIV_001958"
     CDS             complement(<1..844)
                     /locus_tag="AC1PIV_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HIP6612930.1"
                     /translation="MYRKVMKMILSKRFKNRRKELGFTQKELAEGICEQSLISRVEKL
                     GVAPTSDILFALSQRLQVSMDYFFDESVSDKAPDITVFKRLVDKALFTRSYDQLAYLV
                     EAEKQKEAVHSQESSEYLTYLACIVDFHHYHKEDIAIGCMEELSHRISKKSSFYLDVY
                     NSLVNFYALASRDEDLDGLYEGISEKLSHLDISNTECFHKYIKIRYNHAHYLFKRKRQ
                     SQAIDELTDLIETLRDKKSCYFLADMLCLIANVGEGFLSKDEILSYYREAECLFKFFG
                     PQNSY"
BASE COUNT          287 a          188 c          120 g          287 t
ORIGIN      
        1 gataactatt ttgcggacca aaaaatttga atagacattc tgcttctcta tagtaggaga
       61 gaatttcatc ttttgataga aatccctctc cgacatttgc gattaaacaa agcatatctg
      121 ccaaaaaata acaactcttc ttatctcgca atgtttcaat taggtctgtc aattcatcaa
      181 ttgcctgtga ctgcctcttc cttttaaaaa gatagtgagc gtgattgtag cgaatcttga
      241 tatacttatg aaaacactct gtgtttgata tatccaagtg gctaagcttt tctgaaatcc
      301 cctcatacaa accatctaaa tcctcatctc gagaagccaa ggcataaaaa ttaaccaagc
      361 tgttgtatac atccagataa aaactagatt tcttactgat tcgatgacta agttcttcca
      421 tacatccaat tgcaatatcc tccttatgat aatgatgaaa gtccactata caagccagat
      481 aagttaaata ttcactgctt tcctgcgaat gaacagcttc tttctgcttc tctgcctcta
      541 caagataagc cagttgatca taggaacgag tgaacagagc tttgtccacc aatcgtttaa
      601 ataccgtaat atcaggcgct ttatctgata cactttcatc aaaaaaatag tccatagaca
      661 cctgtaagcg ttgtgataag gcaaataata tatccgatgt aggagcaact cctaattttt
      721 caactcgact aatcaaactc tgctcacaaa ttccctctgc aagctccttt tgagtaaagc
      781 caagttcctt tcttctattt ttaaaacgtt tactaagaat cattttcata acctttctgt
      841 acatttacat cttaaataaa atctctatat agattattat at
//
LOCUS       DBNFCO010000166          850 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.170, whole genome shotgun sequence.
ACCESSION   DBNFCO010000166 DBNFCO010000000
VERSION     DBNFCO010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 850)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 850)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..850
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.170"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            29..>850
                     /locus_tag="AC1PIV_001959"
     CDS             29..>850
                     /locus_tag="AC1PIV_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein"
                     /protein_id="HIP6612931.1"
                     /translation="MSHWNQFLTEITYSIIQAHTDQKSLSLYIPFEDSLSKSLAFDTI
                     SQELLESEIDGNGTVLYSDFGDNNITDEYKLSFAEKFFKPISVSVNNSIQGFGTAGLS
                     LKYDSTEIEKKILNNSNNYRLIFLIQHWEWLGSELKLFFIRLLNNISHYEKQYNKSII
                     IVIGGSELKNNDIRFSKNFDVHHFELNDLKDTLGNIIQTSNISDNLEDTLYPLTKGNL
                     EKIYNFILLSQNNSKIEKLLDDLLNTIEIDFRKNKIEIDFIYQLSVLPEYFNPYDA"
BASE COUNT          324 a          116 c          124 g          286 t
ORIGIN      
        1 aaattgttat cggtaggaaa gtttaattat gtctcattgg aatcaatttt taacagaaat
       61 tacttattca attattcaag cacatacaga tcaaaagtca ctttcactat atatcccgtt
      121 cgaagattct ttatcaaaat ccttagcatt tgatacaata tcacaggaac tattggaaag
      181 cgaaattgac gggaatggta cagtattgta tagtgatttc ggagataaca atattacaga
      241 cgagtataaa ctttcatttg cagaaaaatt tttcaagcct atttcagtat ctgttaataa
      301 ctcgatacaa ggatttggaa cagctggtct gtcattaaaa tatgattcaa ctgagataga
      361 gaagaaaata ctaaataata gcaacaatta cagattaata tttctaatcc aacattggga
      421 gtggctaggg agtgaactaa aattattttt tatacgcctt ctcaataata tctcccatta
      481 tgaaaagcaa tataataaat cgattattat tgtaattgga ggctcggagt taaaaaataa
      541 tgatattaga ttttcaaaaa actttgatgt tcatcatttt gaattaaacg atttaaaaga
      601 tactttaggt aatattatac aaacttcaaa catctctgat aacttagagg atacactgta
      661 tcctctaaca aagggaaact tggaaaaaat ttataatttt attttactat cacagaataa
      721 ttctaagatt gaaaagttat tagatgattt gttaaatacg attgaaatag actttagaaa
      781 gaataaaatt gaaattgatt tcatttatca gctatcagtc cttcctgaat atttcaaccc
      841 gtatgatgcc
//
LOCUS       DBNFCO010000167          828 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.171, whole genome shotgun sequence.
ACCESSION   DBNFCO010000167 DBNFCO010000000
VERSION     DBNFCO010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..828
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.171"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            55..>828
                     /locus_tag="AC1PIV_001960"
     CDS             55..>828
                     /locus_tag="AC1PIV_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002275998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HIP6612932.1"
                     /translation="MMMKKYIMMGLVLLATMTLSACSGNATQEDTSLKDVQEKGKLIV
                     ALNPEFPPFEFRTLVDGKDTIVGADIELAKAIGQELGVEVEFSAMSFDNVLNNVQSGQ
                     SDIAISGISATEERAKVYDFSIPYYTSTNKVIINKEDLAQYTSLDSLAEANIGAQKGS
                     IQEQIIKEQLPSSTVIALASNGELINQLKSQKVEAVIFEEPIAKAYVAKNDDLVILDT
                     EIKSSYSDAYAIALPKGSTALKEKVDSVITKLVESGQMDQ"
BASE COUNT          285 a          127 c          175 g          241 t
ORIGIN      
        1 atgttttata taaaaaacgg tataagtatg cacaggatta ttttaaagga gaatatgatg
       61 atgaaaaaat atattatgat gggattggtt ttgttggcaa cgatgaccct aagtgcttgc
      121 agtggaaatg ctactcaaga agatacttcc ttgaaggatg ttcaggaaaa gggaaaacta
      181 attgttgcat tgaatccaga atttccacca tttgagttta gaacactggt tgatggaaaa
      241 gatacaatcg ttggagctga cattgagctt gcaaaagcca ttggtcaaga attgggtgta
      301 gaagtcgaat tttcagcgat gagttttgat aatgttttga acaatgtcca gtcagggcaa
      361 tcggatattg ccatttcagg aatttcagcc actgaagagc gtgcaaaagt gtatgatttt
      421 tccattcctt actacacctc aaccaataaa gttattataa ataaagagga tcttgcacaa
      481 tatacatcgc ttgattctct agctgaggca aatataggag cacaaaaagg ttctattcaa
      541 gaacaaatta ttaaagaaca gcttccgtcc tccacggtta ttgctctagc ttcgaacggc
      601 gagctaatta atcaattaaa atcacagaag gtagaagcag ttatttttga agagccgatt
      661 gcgaaagctt atgttgccaa aaatgatgac ttggttattt tagatactga gataaaaagt
      721 agctattcag atgcctatgc tattgccttg ccaaaaggaa gtacagcttt aaaggaaaaa
      781 gttgactctg tcattacaaa actagtggaa tctggacaga tggatcaa
//
LOCUS       DBNFCO010000168          802 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.172, whole genome shotgun sequence.
ACCESSION   DBNFCO010000168 DBNFCO010000000
VERSION     DBNFCO010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 802)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 802)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..802
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.172"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            159..>802
                     /locus_tag="AC1PIV_001961"
     CDS             159..>802
                     /locus_tag="AC1PIV_001961"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HIP6612933.1"
                     /translation="MHYKHLLFDLDHTLLDFSRGEEVALTQFLTAMEVEDIQAFKEVY
                     RPLNQSMWKDLEKGNITKKELINTRFSRTFAHFGRQVDGREMALRYQEFIGRQGQIFT
                     GADKLLQELTHRGYQIYAATNGVTYIQENRLLHSPIQSYFKEVFISEQMGTQKPATDF
                     YEKIAEQIAGFQFAQALMIGDSLTADIQGGNNAGMDTVWYNPTHMINNSKAVPT"
BASE COUNT          263 a          142 c          179 g          218 t
ORIGIN      
        1 tatctgccga taaaatacag aaagccaaga tatatctgag gctaagcggt ttaaaaagga
       61 gcggttctta aaaatgaatt ttacgatgat cactatagat tagaaacgaa ttgatttcac
      121 tcaaatagag ggtgttttta gagaggaaaa tcccaaaatt gcactacaaa catttattat
      181 tcgatcttga ccatactctt cttgatttta gccgtggaga agaagtagcc ttaacccagt
      241 ttttgacagc tatggaggtt gaagatattc aagcttttaa agaagtttat cgaccgctca
      301 accagagcat gtggaaggat ttggaaaaag ggaacattac aaagaaagag ctaataaaca
      361 cccgcttttc acggaccttt gcccactttg gtcggcaagt tgatggaagg gagatggcct
      421 tgcgctacca agagtttatt gggcggcagg gacaaatttt tacaggtgca gataagcttt
      481 tgcaggaatt gacacaccga ggctaccaga tttatgcagc gaccaacggc gtgacctata
      541 tacaggaaaa tcgcttgctt cactcaccga ttcaatcgta ttttaaagaa gtatttattt
      601 ctgagcagat ggggacgcaa aagcctgcga ctgattttta tgaaaaaata gcagagcaga
      661 ttgcaggttt tcaatttgcc caagccttaa tgattggaga cagtttgaca gcagatattc
      721 aaggcggaaa taatgctggt atggatactg tttggtataa tccgactcac atgataaata
      781 atagtaaggc agttccaacc ta
//
LOCUS       DBNFCO010000169          760 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.173, whole genome shotgun sequence.
ACCESSION   DBNFCO010000169 DBNFCO010000000
VERSION     DBNFCO010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..760
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.173"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(<1..522)
                     /locus_tag="AC1PIV_001962"
     CDS             complement(<1..522)
                     /locus_tag="AC1PIV_001962"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002936347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HIP6612934.1"
                     /translation="MEKVSIIVPIFNTEKYLRECLDSIISQSYTNLEILLIDDGSSDS
                     STDICLEYAEQDGRIKLFRLPNGGVSNARNYGIKNSTANYIMFVDSDDIVDGNIVESL
                     YTCLKENDSDLSGGLLATFDGNYQESELQKCQIDLEEIKEVRDLGNENFPNHYMSGIF
                     NSPCCKLYKNIYIN"
BASE COUNT          257 a          150 c           89 g          264 t
ORIGIN      
        1 gtttatatat atattcttat aaagtttgca acaagggcta ttaaagatac cgctcatata
       61 atgatttgga aaattttcat ttcctaagtc tcgcacctct tttatctctt ccaaatcaat
      121 ttgacacttt tgcagctcag attcttgata atttccatca aaagtagcaa gtaaccctcc
      181 cgacaaatca ctatcattct cttttaaaca ggtgtataag gactcaacaa tgttgccgtc
      241 aacaatatca tcagaatcta caaacataat ataatttgct gtgctatttt tgataccgta
      301 attccttgcg tttgaaacac caccatttgg taaccggaaa agttttattc taccatcttg
      361 ctctgcgtat tccaaacata tatccgttga tgaatctgaa gaaccgtcat ctatcaaaag
      421 aatctctaga ttagtatacg attgggaaat aatgctatct aaacactctc ttaagtactt
      481 ttccgtatta aaaataggta caataatgct gactttttcc atcctctaat tccttttatg
      541 ccgtaacttg ctttgctatc ataaaaatca tcatgtaaaa aatactatct tctatcttgc
      601 cacctataga acatatgctc taccaaatta atagcaactc aaaactctat tcctgccaat
      661 ttatgtttgc agttgtttgt taatagttga ttccatagta gatatagaat ttaataaaca
      721 aaaacatatt ggcataaata caaaacttaa atttacaata
//
LOCUS       DBNFCO010000170          733 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.174, whole genome shotgun sequence.
ACCESSION   DBNFCO010000170 DBNFCO010000000
VERSION     DBNFCO010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 733)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 733)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..733
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.174"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(105..178)
                     /locus_tag="AC1PIV_001963"
     tRNA            complement(105..178)
                     /locus_tag="AC1PIV_001963"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(142..144),aa:Arg,seq:acg)
     gene            complement(197..280)
                     /locus_tag="AC1PIV_001964"
     tRNA            complement(197..280)
                     /locus_tag="AC1PIV_001964"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(244..246),aa:Leu,seq:taa)
     gene            complement(288..359)
                     /locus_tag="AC1PIV_001965"
     tRNA            complement(288..359)
                     /locus_tag="AC1PIV_001965"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(325..327),aa:Gly,seq:gcc)
     gene            complement(372..444)
                     /locus_tag="AC1PIV_001966"
     tRNA            complement(372..444)
                     /locus_tag="AC1PIV_001966"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(409..411),aa:Thr,seq:tgt)
     gene            complement(459..540)
                     /locus_tag="AC1PIV_001967"
     tRNA            complement(459..540)
                     /locus_tag="AC1PIV_001967"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(504..506),aa:Leu,seq:tag)
     gene            complement(544..616)
                     /locus_tag="AC1PIV_001968"
     tRNA            complement(544..616)
                     /locus_tag="AC1PIV_001968"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(581..583),aa:Lys,seq:ttt)
     gene            complement(662..733)
                     /locus_tag="AC1PIV_001969"
     tRNA            complement(662..733)
                     /locus_tag="AC1PIV_001969"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(699..701),aa:Asp,seq:gtc)
BASE COUNT          189 a          217 c          154 g          173 t
ORIGIN      
        1 gaacctgcga caccttggtc ccaaaccaag tactctacca agctgagcta cttcccgata
       61 ctattaaaaa taaagctccc ctaacgtctc cattaagcga gtgatgcacc ctagaggatt
      121 cgaacctcta accgcctgat tcgtagtcag gtactctatc cagttgagct aagggtgcta
      181 actattataa tcttcatgcc gaggaccgga atcgaaccgg tacgatgttg ccatcgcagg
      241 attttaagtc ctgtgcgtct gccagttccg ccaccccggc ctctcaaagc gaacgacggg
      301 attcgaaccc gcgaccccca ccttggcaag gtggtgttct accactgaac tacgttcgca
      361 atctttccta atgccggcta catgacttga acacgcgacc ctctgattac aaatcagatg
      421 ctctaccaac tgagctaagc cggcctattt ccattctatg cgggttaagg gacttgaacc
      481 cccacgcccg aaagcgccag atcctaaatc tggtgcgtct gccaattccg ccaaacccgc
      541 atatgactcg tgctgggctc gaaccagcga cccattgatt aaaagtcaat tgctctacca
      601 actgagctaa cgagtcttta cttaattata ttacttgaaa catatgattg attcgtttca
      661 acggtcccga cgggaatcga acccgcgatc ttcgccgtga cagggcgacg tgataaccgc
      721 tacactacgg gac
//
LOCUS       DBNFCO010000171          695 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.175, whole genome shotgun sequence.
ACCESSION   DBNFCO010000171 DBNFCO010000000
VERSION     DBNFCO010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 695)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 695)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..695
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.175"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            <1..>695
                     /locus_tag="AC1PIV_001970"
     CDS             <1..>695
                     /locus_tag="AC1PIV_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2971 domain-containing protein"
                     /protein_id="HIP6612935.1"
                     /translation="EDLRIINQYVEINIQDNEKFIQQYLDYLKELGADAIAESQKVLQ
                     DLNKYTDSDIMKSQIIELLDLTILPVSEPHSSEEIVEKIKGAIDEIRSALIIDAKKLK
                     ENEFYGHYTTIDTLVNFLFKPETEENKNCPTYLRLSNANQLNDPMEGKALLAILGLDA
                     HMEQYYKPTNVFLSSLTVVKDSLPMWKEYAEESRGAFLEYDQDYLETIVKHDVIEFAK
                     VHYITTDEKQNITG"
BASE COUNT          254 a           99 c          132 g          210 t
ORIGIN      
        1 gaagacttac gtataattaa tcaatatgta gaaataaata tacaggataa tgagaagttt
       61 attcaacagt accttgacta tctaaaggaa ttgggggcag atgcaattgc agaatctcag
      121 aaagttctac aagacttgaa taagtatacg gattctgaca ttatgaaaag tcagataata
      181 gagttactag atttaactat cttgcctgtt agcgaacctc attcaagcga ggaaatcgtt
      241 gagaaaataa agggagctat tgatgaaatt cgttctgcat tgataattga tgcaaagaaa
      301 ttaaaagaga atgaatttta tggccactat actacaatag acaccttggt taatttctta
      361 tttaaaccag agacggaaga aaataaaaat tgtccaacct atttacgttt gtcaaatgct
      421 aatcaattga atgatccgat ggaaggaaaa gccttactcg ccatccttgg tttagatgcc
      481 catatggaac agtattataa accaaccaat gtgtttcttt catccttgac agttgttaaa
      541 gatagtttac ctatgtggaa agaatatgct gaggagtcta ggggagcatt tctggaatat
      601 gatcaagatt acttggaaac tattgtcaag catgatgtta ttgaatttgc taaagttcat
      661 tatattacta cagatgaaaa gcaaaatatt actgg
//
LOCUS       DBNFCO010000172          650 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.176, whole genome shotgun sequence.
ACCESSION   DBNFCO010000172 DBNFCO010000000
VERSION     DBNFCO010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 650)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 650)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..650
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.176"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            105..293
                     /gene="rpmB"
                     /locus_tag="AC1PIV_001971"
     CDS             105..293
                     /gene="rpmB"
                     /locus_tag="AC1PIV_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HIP6612936.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
BASE COUNT          244 a           97 c          132 g          177 t
ORIGIN      
        1 aaaatgaaaa taattcttgc caagtccaat cttttctgtt agaataatat ggtatgtggt
       61 gctagcacat ccgatatatt tgatcaaatg aggaggaaga tacaatggct aaagtatgtt
      121 atttcactgg tcgtaagact gtatcaggta acaaccgttc acacgctatg aaccaaacta
      181 aacgtgcagt taaaccaaac cttcaaaagg taactgtttt gattgatggt aaacctaaaa
      241 aagtttgggc ttcagcgcgt gcactaaaat caggcaaagt tgaacgtgta taataacaaa
      301 gtcgttagaa aaatctagcg acttttgttt ttggaaaaaa tagcctagat ataaagtcgg
      361 tgaggagcaa attcgaccac tacataatga ataggaaaga atatcagcta tatagctctt
      421 cacattgctg ttgaaaagtt aacaaagaag gaatgttgtc aaaaataaac tgtgtattga
      481 tgtggaagat ttttccaagt tcgaacattt aaacttggat tgacattagg agttgtacga
      541 gagagcatcc gtacgggttc tacaagaagg gaatcacgaa ctggaagaat agagagtgtt
      601 taaaaaaatc caaaaaatct caaaaaaccg gttgacaatg tatataagtc
//
LOCUS       DBNFCO010000173          618 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.177, whole genome shotgun sequence.
ACCESSION   DBNFCO010000173 DBNFCO010000000
VERSION     DBNFCO010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 618)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 618)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..618
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.177"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(<1..>618)
                     /locus_tag="AC1PIV_001972"
     CDS             complement(<1..>618)
                     /locus_tag="AC1PIV_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HIP6612937.1"
                     /translation="DLMVIGKYGQYLLNEYQALVLKQINETGSVESLIGYFSDIAGEC
                     ETKIKKLLLDTLKLFLKKEFIVKGVSVYPKHIYGEVGKFYPRKIVIELTNKCHLQCTH
                     CFKEAGPINRNFLKYEELINFLDRVKGKVYEIQLTGGEPMAHPHFKEISKYATENFQE
                     VTMTTTGHLINSKSIIYLKGMSYIQISLYHHNPILNDQITNGKDT"
BASE COUNT          191 a          120 c           71 g          236 t
ORIGIN      
        1 aatgtatcct ttccattggt aatttggtcg tttagaatcg gattatgatg atataaagaa
       61 atttgaatgt agctcattcc cttcaaataa attatacttt tggaattaat taaatgacca
      121 gtggttgtca ttgttacttc ttgaaagttc tccgtagcat attttgaaat ctctttaaaa
      181 tgaggatgtg ccatcggctc cccacccgtt aactgtattt cataaacctt tccttttacc
      241 ctatctaaaa aatttattag ctcttcatac ttcaaaaaat tcctgttaat tggtccagct
      301 tccttaaaac agtgtgtaca ctgtaaatga catttattcg ttaattctat aactattttc
      361 ctagggtaaa atttcccaac ttcaccataa atatgcttcg gataaacaga aactccttta
      421 acaataaact ctttcttcaa gaataatttt aatgtatcca ataatagctt ttttattttt
      481 gtttcacatt cccccgctat atcagagaag taacctatca aactttctac actacccgtt
      541 tcgtttatct gttttaaaac taacgcttga tattcattta ataagtattg accgtatttt
      601 cctataacca tcaaatct
//
LOCUS       DBNFCO010000174          613 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.178, whole genome shotgun sequence.
ACCESSION   DBNFCO010000174 DBNFCO010000000
VERSION     DBNFCO010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 613)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 613)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..613
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.178"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            <1..>613
                     /locus_tag="AC1PIV_001973"
     CDS             <1..>613
                     /locus_tag="AC1PIV_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HIP6612938.1"
                     /translation="IVRAKNRLHKVLQVTFPELENILSTPTGEQYWNLVITFPCKDFV
                     LDLSKNELSKSIRQSTSKRISDKRVAYLAEKLTALANQSYCAVKKTSPILEEVHYYAK
                     ELLRLSEQRQAVLDQMVELAQPLPEYDILLSIPGIAETTATSIIGELGDIRRFQSANQ
                     INAFIGIDLRHYESGNFLAKEHITKRGNPYARKILFKCIHNIAS"
BASE COUNT          184 a          141 c          123 g          165 t
ORIGIN      
        1 attgttcggg ctaaaaaccg tctgcacaag gtcttacaag tcactttccc tgaattggaa
       61 aatatcttgt caacaccaac tggcgaacaa tactggaact tggtcataac ctttccttgc
      121 aaggacttcg tgcttgattt aagcaagaat gaactatcaa agagcattcg tcagtccacc
      181 tcaaaacgga tttctgacaa gcgtgtggcg tacttagctg agaagctgac agcactagct
      241 aatcaatcgt attgtgccgt caagaaaacc tctccaatac tggaagaggt gcattactat
      301 gcaaaagaat tgcttcggct ttctgaacag agacaagcag tcttagacca aatggtggaa
      361 ctagctcagc cattacctga atatgacatt ctgctctcta ttcctggaat agctgagacg
      421 actgcaacaa gtattattgg tgaactggga gatattcgcc gttttcagtc tgccaatcaa
      481 atcaatgcct ttatcggtat tgacctgaga cactatgaat ctggtaactt cctcgctaag
      541 gaacacatta ccaagcgtgg caatccctac gctagaaaga ttctgttcaa gtgtatccac
      601 aatatcgctt cag
//
LOCUS       DBNFCO010000175          531 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.180, whole genome shotgun sequence.
ACCESSION   DBNFCO010000175 DBNFCO010000000
VERSION     DBNFCO010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 531)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 531)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..531
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.180"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            165..>531
                     /locus_tag="AC1PIV_001974"
     CDS             165..>531
                     /locus_tag="AC1PIV_001974"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIP6612939.1"
                     /translation="MKLLKKTSSLNLIDFEQADTYNLIENIVQDSTYKPFQLFNAIIG
                     VITGFLSLLTSIIYVSTWNVAVSTFLLIIPVISLVIFMRVGQLEFLIQWERANSEREV
                     WYINYLLTHDFSFKEIKLNG"
BASE COUNT          181 a           70 c           80 g          200 t
ORIGIN      
        1 tatttatcta tcaagaatta atcaatgctg ttttaaaaaa aggaagtaac attttttcag
       61 tattaattgt ctatatatta atgcaaatga tgctatcaat actaagtcag ttaaactcat
      121 atataagtga gaaatttaat atgaacttgt cctataatct caatttgaag ttattgaaaa
      181 aaacatcatc tctaaattta atagattttg aacaagcaga tacatacaat ctcattgaaa
      241 atattgtaca agatagtaca tataagccgt tccaactttt caatgctatc attggtgtga
      301 ttacagggtt tctatcttta ttaacaagta ttatttatgt gtccacttgg aatgtggcag
      361 tatcgacttt tttactgata attcctgtta tttccttagt aatttttatg cgtgttggcc
      421 agctagaatt tttgattcaa tgggagcgag caaattcgga gagggaagtt tggtacatca
      481 attatcttct tactcatgat ttttcattta aagagattaa actaaatggt a
//
LOCUS       DBNFCO010000176          520 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.181, whole genome shotgun sequence.
ACCESSION   DBNFCO010000176 DBNFCO010000000
VERSION     DBNFCO010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 520)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 520)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..520
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.181"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(72..159)
                     /locus_tag="AC1PIV_001975"
     tRNA            complement(72..159)
                     /locus_tag="AC1PIV_001975"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(123..125),aa:Ser,seq:gga)
     gene            complement(162..515)
                     /gene="ssrA"
                     /locus_tag="AC1PIV_001976"
     tmRNA           complement(162..515)
                     /gene="ssrA"
                     /locus_tag="AC1PIV_001976"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:15.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
BASE COUNT          148 a          128 c           95 g          149 t
ORIGIN      
        1 tttcatttgt tttcagttgt atcattcaca gacaaaaaaa gaacgactat cagtcgttct
       61 tcaataacat acggaagaca tgggattcga acccacgcac gctgttacac gcctaccgcg
      121 tttccaacac ggcctcttga gcctcttgag taatcttcca tatatggagc tggtgggagt
      181 cgaacccacg tccaaacacc tgctaactta ttcgtctaca accataggtt atgtcttgct
      241 ttaactttaa cttgaactcg atacataact caaacctaga ccaagcgagt cagtaaatct
      301 cttttggaac tgcctgactc aatcccaacg tagcttgcta ttttaagacc aatcagcaaa
      361 cacaagcaat tcgcgactgg tcacgcaggc aggttattaa gctgctaatg cgtaagtgtt
      421 tgtatttttt gcagttatat ttaactggca tttttacatc tgccgatgag ttgcagaaca
      481 agcctcataa tgcctgtcga atccgtaaca accccgtagg
//
LOCUS       DBNFCO010000177          477 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.182, whole genome shotgun sequence.
ACCESSION   DBNFCO010000177 DBNFCO010000000
VERSION     DBNFCO010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 477)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.182"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(<1..314)
                     /locus_tag="AC1PIV_001977"
     CDS             complement(<1..314)
                     /locus_tag="AC1PIV_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SSU0592/SSU0593 family protein"
                     /protein_id="HIP6612940.1"
                     /translation="MKQLVTKRSYKIGLSAMALVLLMTTAGGATAHASTGTYSVETRG
                     DAKVYRLLETPAGSFTQGGIVLKPVNNSTTKPSETKSWFDSFWSSVKTFWEAICRGVG
                     WC"
BASE COUNT          167 a          110 c           67 g          133 t
ORIGIN      
        1 taacaccatc caactccacg acagattgct tcccaaaatg tttttacact actccaaaaa
       61 gaatcaaacc atgatttggt ttcagatggt ttagttgtag aattattcac aggtttcaaa
      121 actatgcccc cctgtgtaaa agaccccgcc ggagtttcca acagcctata cactttggca
      181 tcacctcgag tttcgacact ataggtaccc gtacttgcat gtgcagtggc accacctgca
      241 gtggtcatta gcaagaccaa agccatagca ctcaaaccaa ttttataact acgttttgtt
      301 acaagttgct tcattgttga aatatctcct ttatacgata ttcgtctcta caaatgatag
      361 tatagcacaa acagacaact caaattccaa ctttagaaaa aggttagata aaaaactata
      421 aaactccaag atatgcatat taacacaaga acaaaaatac acatgcaata ttatatt
//
LOCUS       DBNFCO010000178          403 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.183, whole genome shotgun sequence.
ACCESSION   DBNFCO010000178 DBNFCO010000000
VERSION     DBNFCO010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..403
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.183"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            <1..>403
                     /locus_tag="AC1PIV_001978"
     CDS             <1..>403
                     /locus_tag="AC1PIV_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="NisI/SpaI family lantibiotic immunity
                     lipoprotein"
                     /protein_id="HIP6612941.1"
                     /translation="SDGLAISINDSYYKVSLSSDVQSNNEMLSLEEFNNNSAGGELAI
                     DPSDCRIVKFNNKKFRISSDIVSDDKLKEFLGVIADSKTFILNTGQEISKSELNKIDY
                     SGSNSNEKREVWDYGEVYLLAEEGTIAVEIN"
BASE COUNT          148 a           40 c           78 g          137 t
ORIGIN      
        1 ttagtgatgg tttagctatt tctataaatg attcttatta taaggtttct ttgagttcgg
       61 atgtgcaatc caataatgaa atgctgagct tggaagagtt caataataat tcagcaggtg
      121 gggaacttgc aattgatcca tctgattgta ggatagttaa atttaataat aaaaaatttc
      181 gtatttcatc tgatattgta tctgatgata aactaaaaga atttctagga gtaatagcag
      241 attcaaaaac atttattttg aatacgggac aagaaatttc taaatcggaa ctaaataaaa
      301 tagattattc tggttctaat tctaatgaaa aaagagaagt ttgggattac ggagaagttt
      361 atttgttagc agaagaagga accatagctg ttgagattaa taa
//
LOCUS       DBNFCO010000179          373 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.184, whole genome shotgun sequence.
ACCESSION   DBNFCO010000179 DBNFCO010000000
VERSION     DBNFCO010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..373
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.184"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            <1..>373
                     /locus_tag="AC1PIV_001979"
     CDS             <1..>373
                     /locus_tag="AC1PIV_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic dehydratase"
                     /protein_id="HIP6612942.1"
                     /translation="IMSLIDSHFLISNINSELIMNFKFEEFISKVKEIDKQNLYYFKL
                     IAISNLIVEYSELEIGDGIEKLQEIYKLMSSLVETPNFLQIDLYNDGQIQLGNENKTQ
                     IVEFAEFLVSNSDHVKRTYLDD"
BASE COUNT          140 a           39 c           57 g          137 t
ORIGIN      
        1 atcatgagtt tgattgatag tcattttcta atttcaaata ttaattcaga attaataatg
       61 aattttaagt ttgaagaatt catttctaaa gttaaagaaa tcgataagca aaatctttat
      121 tattttaaac taatagcaat tagcaactta attgttgaat attctgaatt ggaaattggg
      181 gatgggattg aaaagcttca agaaatctac aagttaatgt catcgttagt tgaaacccct
      241 aattttcttc aaattgatct ttataatgat ggtcaaatcc aattaggtaa tgaaaataaa
      301 actcagatag tagaatttgc tgagtttcta gtaagtaatt cagatcatgt aaagcgtact
      361 tatttagatg att
//
LOCUS       DBNFCO010000180          366 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.185, whole genome shotgun sequence.
ACCESSION   DBNFCO010000180 DBNFCO010000000
VERSION     DBNFCO010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 366)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 366)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..366
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.185"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            8..81
                     /locus_tag="AC1PIV_001980"
     tRNA            8..81
                     /locus_tag="AC1PIV_001980"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:42..44,aa:Met,seq:cat)
     gene            98..171
                     /locus_tag="AC1PIV_001981"
     tRNA            98..171
                     /locus_tag="AC1PIV_001981"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:132..134,aa:Ile,seq:cat)
     gene            178..267
                     /locus_tag="AC1PIV_001982"
     tRNA            178..267
                     /locus_tag="AC1PIV_001982"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:214..216,aa:Ser,seq:tga)
     gene            278..351
                     /locus_tag="AC1PIV_001983"
     tRNA            278..351
                     /locus_tag="AC1PIV_001983"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:312..314,aa:Met,seq:cat)
BASE COUNT           74 a           94 c          100 g           98 t
ORIGIN      
        1 ttattttggc ggtgtagctc agctggctag agcgtccggt tcatacccgg gaggtcgggg
       61 gttcgatccc cttcgccgct atatactctt gtttgctgga cctttagctc agctggttag
      121 agctctcggc tcataaccga gcggtcgtag gttcaagtcc tacaaggtcc atatatcgga
      181 ggattaccca agtccggctg aagggaacgg tcttgaaaac cgtcaggcgt gtaaaagcgt
      241 gcgtgggttc gaatcccaca tcctcctttt ctactaccgc gggatggagc agctaggtag
      301 ctcgtcgggc tcataacccg aaggtcgtag gttcaaatcc tgctcccgca atttctttaa
      361 gaattt
//
LOCUS       DBNFCO010000181          349 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.186, whole genome shotgun sequence.
ACCESSION   DBNFCO010000181 DBNFCO010000000
VERSION     DBNFCO010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 349)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 349)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..349
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.186"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(<1..240)
                     /locus_tag="AC1PIV_001984"
     CDS             complement(<1..240)
                     /locus_tag="AC1PIV_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NisI/SpaI family lantibiotic immunity
                     lipoprotein"
                     /protein_id="HIP6612943.1"
                     /translation="MRKILFSLVVLIGICTLVACRLVDNKTIEFHDQSFNQFTYKGND
                     YTIMNQIVDENDLGTVKESFFKTLVIDRNSQKVVTK"
BASE COUNT          120 a           62 c           33 g          134 t
ORIGIN      
        1 tttagtaaca actttctggc tatttctatc aattactaat gttttaaaaa aagattcctt
       61 cacagtacct agatcatttt catcaacaat ttgattcatg attgtataat catttccttt
      121 atatgtaaat tgattaaatg attgatcatg aaactctatt gttttattgt ctaccaatct
      181 acatgcaact aaagtacaaa ttccaataag aacaactaag ctaaataaaa ttttcctcat
      241 gctacttcac ctcctttata acatcatcaa ataataagag tgccctttgc caatttgttg
      301 taacctttaa gttatttagt tcgatcattg ttaacagaat tccaattat
//
LOCUS       DBNFCO010000182          296 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.187, whole genome shotgun sequence.
ACCESSION   DBNFCO010000182 DBNFCO010000000
VERSION     DBNFCO010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 296)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 296)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..296
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.187"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(<1..257)
                     /locus_tag="AC1PIV_001985"
     CDS             complement(<1..257)
                     /locus_tag="AC1PIV_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HIP6612944.1"
                     /translation="MLNKEWYFKNFNMVSELDISGEFIYTGISIVNNMDRIAPEMPTE
                     LFLALYNISVGVERLQKIILVLWEFDEVDSIEDFSESLKIH"
BASE COUNT          102 a           61 c           28 g          105 t
ORIGIN      
        1 ttatgaatct ttagactttc agaaaagtct tctatggaat caacctcatc gaactcccac
       61 aacactaata ttattttctg tagtctttcg actcctacag aaatgttgta taaagccaaa
      121 aataattccg taggcatctc tggagcaatt ctatccatat tatttacaat ggaaatacca
      181 gtatatataa attctcctga gatatccaac tctgaaacca tattaaaatt tttgaaatac
      241 cactctttat ttaacaccct atatctccct aaaattttta tttattcaac tgaatt
//
LOCUS       DBNFCO010000183          254 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.188, whole genome shotgun sequence.
ACCESSION   DBNFCO010000183 DBNFCO010000000
VERSION     DBNFCO010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 254)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 254)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..254
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.188"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            9..>254
                     /gene="rpsT"
                     /locus_tag="AC1PIV_001986"
     CDS             9..>254
                     /gene="rpsT"
                     /locus_tag="AC1PIV_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HIP6612945.1"
                     /translation="MEVKPLANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANP
                     SEELFRAASSAIDKAETKGLIHKNKASRDKARLASKLA"
BASE COUNT           99 a           53 c           50 g           52 t
ORIGIN      
        1 aagaaagggt ggaggtgaaa ccattggcaa acattaagtc agctatcaaa cgcgctgaat
       61 tgaacgttaa acaaaacgag aaaaactcag cacaaaaatc agctatgcgt actgcaatca
      121 aagcatttga agctaaccca tctgaagagc ttttccgtgc tgctagttca gcaatcgata
      181 aagcagaaac taaaggtttg attcacaaaa acaaagcaag ccgcgataaa gcacgtcttg
      241 catcaaaact tgct
//
LOCUS       DBNFCO010000184          237 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.denovo.189, whole genome shotgun sequence.
ACCESSION   DBNFCO010000184 DBNFCO010000000
VERSION     DBNFCO010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 237)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 237)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..237
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.denovo.189"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            complement(<1..207)
                     /locus_tag="AC1PIV_001987"
     CDS             complement(<1..207)
                     /locus_tag="AC1PIV_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HIP6612946.1"
                     /translation="MRVVFGIDVSKASSEVAILVNGEKVHGYTISNDAIGFARLLGDL
                     RTVHKPEIIFEATGVYSRRLQTFLD"
BASE COUNT           67 a           55 c           47 g           68 t
ORIGIN      
        1 atctagaaaa gtttggagac ggcgagaata gacacctgtt gcttcaaaga tgatttctgg
       61 cttatggacg gttctcaaat cgccaagtag ccgagcaaag ccgatggcgt cattggatat
      121 ggtatagcca tgaactttct caccattgac tagaatggcc acttctgaac ttgccttact
      181 cacatcaatc ccaaaaacta ctcgcatgat attacctctt tgtcttgaat gattcct
//
LOCUS       DBNFCO010000185         3866 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.guided.113, whole genome shotgun sequence.
ACCESSION   DBNFCO010000185 DBNFCO010000000
VERSION     DBNFCO010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3866
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.guided.113"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            111..1838
                     /locus_tag="AC1PIV_001988"
     CDS             111..1838
                     /locus_tag="AC1PIV_001988"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIP6612947.1"
                     /translation="MFRLIFDYIKRHKWLYLLVAVTLIIYDATLLLPTQIIQRMVDIL
                     TKNELTQAILVQEMTLLLLVTVLNYATAFIWHLKLFQASVNFKFDMQQRAFKKLVTMR
                     TPFYEKFRSGDVMTRFSTDVDGLMEMVGYGLMIVVYAGGMLAFIIPTMFFIDWKISLV
                     ALLPMLFMTLCIFFIGRKQDKAIDANREAVAQLNNEVLEVIEGIRVTRAYSKKANQKA
                     QFQARTKQLAQGGDRITSLQSLYNPLATVCLGLSTIFVLLMGAQAVKAGQLTLGQVIA
                     LQLYVGSLLEPFWTLADFILVYQTGKTSFEKLQELIETGDDLEADGSKEIAELSSISF
                     KNYSFSYPQAERASLQDINWTLKAGQTVGIVGKTGSGKTTLVRQFLRQYPIGQGNFFI
                     NHQSILDFKRSSIEEKIGYVPQEHILFSRSVGENIALGKVASSSEEIEQAIATAAFSQ
                     DLKRMSDGLDTMIGERGVSISGGQKQRISIARAFLREPDLLILDDSLSAVDARTERQI
                     IQNIQKERAGKTNVIVTHRLSAVNHADWVLVLDEGRIVEEGRPADLLAQRGWYYEQYQ
                     RQQSQEGGE"
     gene            1838..3577
                     /locus_tag="AC1PIV_001989"
     CDS             1838..3577
                     /locus_tag="AC1PIV_001989"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015646585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HIP6612948.1"
                     /translation="MTILGFLLKQIRRVKCLFIVAVGFYLLASTMVRLAPLLIQQAID
                     GPITDLSKGLPFDEAVFLNQSVQYMGMIILGAIGFYLSMRLLMHCANRIAENLRNQAY
                     DVMQRLPISYFDDKPAGKIATRIVNDTETLRTQFYGTLVNAFNNIVRLLFTYGVLFYM
                     NRSLGWLMLLLIPLYIGIQFAYKKMTDKPMKDFYDARSDVNTQVNETMNGASLIQLFG
                     QEERIMKEFEVTADKMRRADNKIIWAQSLATWNLSGFLQNLVIAAILTVVGYQFLAGQ
                     DGVTAGKLFVYVNYIEGVFIALGALVQQFPNMLRSFETGKRLMALLEEELEDDCDRIL
                     EVEQGQVVFEHVNFSYEENRPVLKDITIRAEKGETVALVGHTGSGKSSIMNLLYRFYD
                     PQEGCVLIDGKNIRDYSRESLRSHMGIVLQDPYLFTGTIASNVSMNEEEADRTRIMQA
                     LEKVGAGPMLSRLEKGIDEPVVEKGAAFSSGERQLIAFARTLYSDPKILILDEATSHI
                     DTETEEIIQHAMEVVKEGRTTFIIAHRLSTIQNADQILVLDQGRIIEHGKHEELVARG
                     GVYAQMHEIQAKV"
     gene            3631..>3866
                     /locus_tag="AC1PIV_001990"
     CDS             3631..>3866
                     /locus_tag="AC1PIV_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HIP6612949.1"
                     /translation="MKALIFDVDDTLYDQIQPFERALERHIEVAREQIEPLYLSFRRY
                     ADEVFEATAIGKMSLKDSHIYRMKHALADFGYQVS"
BASE COUNT         1092 a          690 c          918 g         1166 t
ORIGIN      
        1 atgcttccct gggctttttt gtgcgcttag cttagaaaag taaggtctat caattgtagc
       61 ttattgaata aagtggcaaa tgataggtta tggatttgta aaggagatat atgtttcgat
      121 taatttttga ctatatcaag cgtcataagt ggctctatct attggttgct gtgaccttga
      181 ttatttatga cgccacactt ttgctaccaa cgcaaatcat tcagcggatg gtcgatatac
      241 taaccaagaa tgaattaaca caggccatat tggttcagga gatgacctta ttgttattgg
      301 taacagtgct gaactatgca acagccttca tttggcatct gaaattattt caggcctctg
      361 tcaatttcaa gtttgatatg cagcaacgtg cctttaaaaa attagtgacc atgcggactc
      421 cattttatga aaaattccgc tcaggagatg tcatgactcg tttttcaacg gatgtggatg
      481 gcctgatgga gatggtgggt tacggtctta tgattgtcgt ctatgcaggc ggtatgttgg
      541 cttttatcat tcccacgatg ttctttattg attggaaaat ttcgctagta gctttactac
      601 cgatgctgtt catgacacta tgtatatttt ttatcgggag aaaacaagat aaggcgattg
      661 atgccaatag agaagctgta gcccagctca ataatgaagt tttggaggtc atcgaaggca
      721 ttcgagtgac tcgggcttat agtaaaaaag caaatcaaaa ggctcaattt caagctcgta
      781 ccaagcaatt ggctcaaggt ggggatcgca tcacttcctt gcaatcattg tataatccat
      841 tagccacagt ctgtttggga ttgtctacta ttttcgtact tctcatgggg gcacaagccg
      901 tgaaagcagg gcaactgacc ttgggacaag taattgccct tcaattgtat gtcggttcgc
      961 ttttagagcc gttttggaca ctagcagatt tcatccttgt ttatcagact ggtaagacat
     1021 ctttcgaaaa actgcaagag ctgattgaga cgggtgatga tttggaggct gatggttcta
     1081 aggaaattgc agagctgtct agtatttcct tcaaaaatta tagctttagt tatccacagg
     1141 cggaaagagc cagcctacag gacatcaatt ggacactgaa agcagggcaa actgtaggta
     1201 tcgttgggaa aactggttcg ggaaaaacga ccttggttcg ccaattctta cgccagtatc
     1261 cgattggtca gggaaatttt ttcatcaatc atcaatctat tttagacttt aaacgttcta
     1321 gtatagagga aaaaattggc tatgttccac aagaacacat tttgttttca aggtctgttg
     1381 gagaaaatat tgccctaggg aaagtagcta gtagctctga ggagattgaa caagccattg
     1441 ccacagcagc ttttagtcaa gatttaaaac ggatgagtga tggtcttgat accatgattg
     1501 gtgagcgtgg tgtgtctatt tctggtggtc agaaacaacg gatttccatt gcccgtgctt
     1561 tcctgcgaga gccagatttg ctaattctag atgattcttt gtcggcagtg gatgctagga
     1621 cagaacgcca gattatccaa aatattcaaa aagaacgtgc aggcaaaacc aatgtcatcg
     1681 tgacccatcg tctatctgct gtcaaccatg cagactgggt actagtcttg gatgaggggc
     1741 gtatcgttga ggaagggcgt ccagctgatt tgcttgccca aagaggttgg tactatgaac
     1801 aataccaacg acaacaaagc caggaaggag gagagtaatg actattttag gttttttatt
     1861 aaaacaaatc cgtcgagtca agtgtctatt tatagtagct gtcggcttct atctattggc
     1921 ttcgaccatg gttcgattgg ctcctctgct gattcagcag gcgattgatg ggccgattac
     1981 ggatttgagc aagggtttgc cttttgatga agctgttttc ttaaaccagt cagttcaata
     2041 catgggaatg attattctgg gagctattgg cttctactta tctatgcgtt tactcatgca
     2101 ttgcgccaat cgtattgctg aaaatctacg taatcaagcc tacgatgtta tgcaacggtt
     2161 gcctatttct tattttgatg ataagcccgc tggaaaaatt gcaactagaa ttgtcaatga
     2221 tacagaaact ctgcggacac aattttatgg gaccttagtt aatgccttta acaatattgt
     2281 tcgtttgctc tttacatacg gtgtcctatt ttatatgaat aggagtcttg gttggctgat
     2341 gttactcttg ataccactct atatcggtat tcaatttgct tacaagaaaa tgacagacaa
     2401 gccgatgaag gatttttatg atgcaaggag tgacgtcaat acgcaggtga atgagaccat
     2461 gaatggtgca agtttgattc aactttttgg acaagaagag cgcatcatga aagaatttga
     2521 agtgactgct gacaagatgc gtcgggcaga taataagatt atctgggccc agtctcttgc
     2581 cacgtggaat ctgagtggtt ttctgcaaaa tttggtcatt gctgcgattt taacggtagt
     2641 cggctatcaa tttcttgcgg gacaggatgg agttacagct gggaaactct ttgtttatgt
     2701 caactatatc gaaggagtct tcattgcttt gggagcgctg gttcaacagt tcccaaatat
     2761 gcttcgctcg tttgaaacag gtaagcgtct aatggccctt ctagaagaag agctggagga
     2821 cgactgtgat cgtattttgg aagttgaaca agggcaagtc gtgtttgaac acgtgaactt
     2881 tagctatgaa gaaaacagac cagttttgaa agatattacc attcgagcag aaaaaggaga
     2941 aacagttgct ctggttgggc atactgggtc tggtaagtct tctattatga atctcctcta
     3001 tcgtttctat gatccacagg agggatgtgt actgattgat gggaaaaaca tccgtgatta
     3061 ttctcgtgaa agcctgcgca gtcacatggg gattgttttg caagatccct atctctttac
     3121 agggacgatt gccagcaatg tttccatgaa tgaagaggaa gcagatagaa caagaatcat
     3181 gcaggcgcta gaaaaagttg gtgcagggcc tatgctatct cgcttagaga aagggattga
     3241 tgaaccggtt gttgagaagg gggcggcctt ttcaagtggg gaacgtcaat tgattgcctt
     3301 tgcgcggaca ctctactctg atcctaaaat tctgatattg gatgaagcaa cttctcatat
     3361 tgatacggag acggaagaaa ttatccaaca tgccatggaa gtggtgaaag aaggtcggac
     3421 aacctttatt attgctcacc gactttctac cattcaaaat gcagaccaga ttcttgtctt
     3481 agatcaaggt cgaattattg aacatgggaa gcatgaagaa ttggttgcac gtggtggagt
     3541 atatgctcaa atgcatgaga ttcaagcaaa ggtgtaataa gcagttaaaa attccaagct
     3601 tttgctggaa ttttttgcta taattgactc atgaaagcct taatttttga tgtagatgat
     3661 acgctttatg atcagattca accgtttgaa cgtgctttgg aaagacacat tgaagtagca
     3721 agggagcaaa ttgaaccact ctacctttcc tttcgcagat atgcggatga agtatttgaa
     3781 gcgacagcaa ttggaaagat gagtttgaaa gacagtcata tttatcggat gaaacatgct
     3841 ttggcagatt ttgggtatca ggtgtc
//
LOCUS       DBNFCO010000186         3445 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.guided.120, whole genome shotgun sequence.
ACCESSION   DBNFCO010000186 DBNFCO010000000
VERSION     DBNFCO010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3445
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.guided.120"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            183..2102
                     /gene="tet(O)"
                     /locus_tag="AC1PIV_001991"
     CDS             183..2102
                     /gene="tet(O)"
                     /locus_tag="AC1PIV_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032490535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(O)"
                     /protein_id="HIP6612950.1"
                     /translation="MKIINLGILAHVDAGKTTLTESLLYTSGAIAEPGSVDKGTTRTD
                     TMNLERQRGITIQTAVTSFQWEDVKVNIIDTPGHMDFLAEVYRSLSVLDGAVLLVSAK
                     DGIQAQTRILFHALQTMKIPTIFFINKIDQEGIDLPMVYQEMKAKLSSEIIVKQKVGQ
                     HPHINVTDNDDMEQWDAVIMGNDELLEKYMSGKPFKMSELEQEENRRFQNGTLFPVYH
                     GSAKNNLGIRQLIEVIASKFYSSTPEGQSELCGQVFKIEYSEKRRRFVYVRIYSGTLH
                     LRDVIKISEKEKIKITEMCVPTNGELYSSDTACSGDIVILPNDVLQLNSILGNEMLLP
                     QRKFIENPLPMLQTTIAVKKSEQREILLGALTEISDGDPLLKYYVDTTTHEIILSFLG
                     NVQMEVICAILEEKYHVEAEIKEPTVIYMERPLRKAEYTIHIEVPPNPFWASVGLSIE
                     PLPIGSGVQYESRVSLGYLNQSFQNAVMEGVLYGCEQGLYGWKVTDCKICFEYGLYYS
                     PVSTPADFRLLSPIVLEQALKKAGTELLEPYLHFEIYAPQEYLSRAYHDAPRYCADIV
                     STQVKNDEVILKGEIPARCIQEYRNDLTYFTNGQGVCLTELKGYQPAIGKFICQPRRP
                     NSRIDKVRHMFHKLA"
     gene            2157..2327
                     /locus_tag="AC1PIV_001992"
     CDS             2157..2327
                     /locus_tag="AC1PIV_001992"
                     /inference="COORDINATES: protein motif:HMM:NF025568.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HIP6612951.1"
                     /translation="MKCEWILCPVCGSKTHNKIRKDTVLENYPLYCPKCRQESLIKVD
                     NLKITVIKEPDA"
     gene            2919..3326
                     /locus_tag="AC1PIV_001993"
     CDS             2919..3326
                     /locus_tag="AC1PIV_001993"
                     /inference="COORDINATES: protein motif:HMM:TIGR02937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed RNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HIP6612952.1"
                     /translation="MDKLFIPVQGCLLEVVREQYADFYRDRERWRYLQKLDARNSLLS
                     LDGFTDSEGNPLDFIADEAADIAETVVNAVMVDRLKAALPLLSDSEQELIQAIFFDGL
                     SEREVGARLGITQSVVNKRKARILRKLRKIIEN"
BASE COUNT         1065 a          611 c          806 g          963 t
ORIGIN      
        1 tcacttttaa tatggggctt agttttttgt acccagttta agaatacttt tatcatgtaa
       61 ttttatatgc ccgaaaacat ataagtgttt tggggctatt ggagttattt acccagtgat
      121 aggagtattt atcactgggt atttttatgc ccttttttgg gtgttgatag gaggaaaatc
      181 acatgaaaat aattaactta ggcattctgg ctcacgttga cgcaggaaag acaacattaa
      241 cggagagttt attgtatacc agtggtgcaa ttgcagaacc agggagcgta gataaaggca
      301 caacaaggac agatacaatg aatttggagc gtcaaagggg aatcactatc cagacagcag
      361 tgacatcttt tcagtgggag gatgtaaaag tcaacattat agatacgcca ggccatatgg
      421 attttttggc ggaagtatac cgttctttat ccgtattaga cggagcagta ttattagttt
      481 ctgcaaagga tggcatacag gcacagaccc gtatactgtt tcatgcacta cagacaatga
      541 agattccgac aatttttttc atcaataaaa ttgaccaaga ggggattgat ttgccaatgg
      601 tatatcaaga aatgaaagca aagctttctt cggaaattat agtgaagcaa aaggttgggc
      661 agcatcccca tataaatgta acggacaatg acgatatgga acagtgggat gcggtaatta
      721 tgggaaacga tgaactatta gagaaatata tgtcagggaa accgtttaaa atgtcagaac
      781 tggaacagga agaaaacagg agattccaaa acggaacgtt atttcccgtt tatcacggaa
      841 gtgctaaaaa caatctgggg attcggcagc ttatagaagt gattgccagt aagttttatt
      901 catcaacgcc tgaaggtcaa tctgaactat gcgggcaggt ttttaagatt gaatattcag
      961 agaaaaggcg gcgttttgtt tatgtgcgta tatatagcgg aacattgcat ttgagggatg
     1021 ttattaaaat atctgaaaaa gagaaaataa aaatcacaga gatgtgtgtt ccgacaaacg
     1081 gtgaattata ttcatccgat acagcctgct ctggtgatat tgtaatttta ccaaatgatg
     1141 ttttgcagct aaacagtatt ttggggaacg aaatgctgtt gccgcagaga aaatttattg
     1201 aaaatcctct ccctatgctc caaacaacga ttgcagtaaa gaaatctgaa cagcgggaaa
     1261 tattgcttgg ggcacttaca gaaatttcag atggcgaccc tcttttaaaa tattatgtgg
     1321 atactacaac gcatgagatt atactttctt ttttggggaa tgtgcagatg gaagtcattt
     1381 gtgccatcct tgaggaaaaa taccatgtgg aggcagaaat aaaagagcct actgttatat
     1441 atatggaaag accgcttaga aaagcagaat ataccatcca catagaagtc ccgccaaatc
     1501 ctttctgggc ttctgtcggg ttgtccatag agccgctccc tattggaagc ggagtgcagt
     1561 atgaaagcag agtttcactt ggatatttaa accaatcgtt ccaaaatgcg gttatggagg
     1621 gggttcttta tggctgcgag caggggctgt atggatggaa agtgacagac tgtaaaatct
     1681 gttttgaata tggattgtat tatagtcctg taagtacccc cgcagacttt cggctgcttt
     1741 cccctatcgt attggagcag gctttaaaaa aagcagggac agaactatta gagccatatc
     1801 tccactttga aatttatgca ccgcaggaat atctctcacg ggcgtatcat gatgccccaa
     1861 ggtattgtgc agatattgta agtactcagg taaagaatga cgaggtcatt ctgaaaggag
     1921 aaatccctgc cagatgtatt caagaataca ggaacgattt aacttatttc acaaatgggc
     1981 agggagtctg cttgacagag ttaaaaggat accagccagc tattggtaaa tttatttgcc
     2041 aaccccgccg cccgaatagc cgtatagata aggttcggca tatgttccac aagttagctt
     2101 aacagcttgc aaaagtcata taaaatgaga tttgaaagga ttagagacta attatgatga
     2161 aatgcgaatg gatattgtgt cctgtttgtg ggagcaaaac ccataataaa attaggaagg
     2221 acactgtttt ggagaattat cccctttatt gtccaaaatg cagacaagaa agcttgatta
     2281 aagttgacaa cttgaagata actgtcatca aagagccaga cgcttaagac gcatagccga
     2341 tgaaattgtg gaacaattca cgaatcatcg gctctttttg tttcgtattt gaaagaacaa
     2401 actcaccaaa taaaaaaaac gatattcggg tgggttattt tgttataccc taaattaccc
     2461 tctgaatttg tttttaaatt tggagggatt tttttatgtt cttttttcgg gcggttattc
     2521 atctgctcat acgaagtaaa atttatcaat acatagcata tcagagaatg gcaggaaacc
     2581 agttaaaaaa atttctgcca gtgcagcggt acttctcacc ttgaaagtgg aagtacaatc
     2641 tccatacaac agaatttgta tttcccataa ccgtgaaggt cacagagcct ttgcggtttt
     2701 tcttttgtcg ttttttgttg gaaagtgccg cagggctgtt tctggtgtgc gttgccgctc
     2761 cccgcctctc catctggatt tttacatttc aaaaattcag attggaggta ttagcggtga
     2821 aatacgcacc aagaaaagta tatatcaaag aaagcggcgg ctatgtggaa ctgtcctata
     2881 cggatttctg ccgccgcagg caagccgaca agggatatat ggacaagctg tttatccccg
     2941 tccaaggttg tctgcttgaa gtcgtaaggg agcaatatgc ggacttctac cgtgacaggg
     3001 agcggtggcg ttacctgcaa aaattagatg cgaggaacag cctgctatct ctggacggat
     3061 ttacggacag cgaggggaat cctctggact ttatcgctga tgaagcggcg gacattgcgg
     3121 aaaccgttgt caatgctgtt atggtggaca ggctgaaagc cgccctgcct ttgttgtcgg
     3181 atagtgagca ggagttgata caggcaatct tttttgacgg actttccgag cgtgaagtcg
     3241 gggcgaggtt aggcataacc cagagcgttg tgaacaaacg caaagccaga atcctaagaa
     3301 aactaagaaa gataatagaa aattaaaatt taaggcgttc agcccccttg ttttttcctt
     3361 tgggaaaatg agggggcttt tctctgccct ctcaatcaat tctgattgga ggaagaaaga
     3421 atggcataca accacggacg ggagg
//
LOCUS       DBNFCO010000187         1430 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.guided.147, whole genome shotgun sequence.
ACCESSION   DBNFCO010000187 DBNFCO010000000
VERSION     DBNFCO010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1430
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.guided.147"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            141..878
                     /gene="erm(B)"
                     /locus_tag="AC1PIV_001994"
     CDS             141..878
                     /gene="erm(B)"
                     /locus_tag="AC1PIV_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011100845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HIP6612953.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTITYEQVLSIFNSYLLFNGRK"
     gene            1048..1308
                     /locus_tag="AC1PIV_001995"
                     /pseudo
     CDS             1048..1308
                     /locus_tag="AC1PIV_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
BASE COUNT          546 a          236 c          227 g          421 t
ORIGIN      
        1 ttacgcagat aaataaatac gttagattaa ttcctaccag tgactaatct tatgactttt
       61 taaacagata actaaaatta caaacaaatc gtttaacttc tgtatttgtt tatagatgta
      121 atcacttcag gagagattac atgaacaaaa atataaaata ttctcaaaac tttttaacga
      181 gtgaaaaagt actcaaccaa ataataaaac aattgaattt aaaagaaacc gataccgttt
      241 acgaaattgg aacaggtaaa gggcatttaa cgacgaaact ggctaaaata agtaaacagg
      301 taacgtctat tgaattagac agtcatctat tcaacttatc gtcagaaaaa ttaaaactga
      361 atactcgtgt cactttaatt caccaagata ttctacagtt tcaattccct aacaaacaga
      421 ggtataaaat tgttgggaat attccttacc atttaagcac acaaattatt aaaaaagtgg
      481 tttttgaaag ccgtgcgtct gacatctatc tgattgttga agaaggattc tacaagcgta
      541 ccttggatat tcaccgaaca ctagggttgc tcttgcacac tcaagtctcg attcagcaat
      601 tgcttaagct gccagcggaa tgctttcatc ctaaaccaaa agtaaacagt gtcttaataa
      661 aacttacccg ccataccaca gatgttccag ataaatattg gaagctatat acgtactttg
      721 tttcaaaatg ggtcaatcga gaatatcgtc aactgtttac taaaaatcag tttcatcaag
      781 caatgaaaca cgccaaagta aacaatttaa gtaccattac ttatgagcaa gtattgtcta
      841 tttttaatag ttatctatta tttaacggga ggaaataatt ctatgagtcg cttttttaaa
      901 tttggaaagt tacacgttac taaagggaat ggagataaat tattagatat actactgaca
      961 gcttccaaga agctaaagag gtccctagcg cctacgggga atttgtatcg ataaggggta
     1021 caaattccca ctaagcgctc gggacccctt gtaggaaaat gtcctaagtg tggcaacaat
     1081 attgtattaa aaaaatcgtt ttatggttgt tcaaattatc ctgaatgtaa gtttacttta
     1141 gctgaacatt ttagaaagaa aaaactaacc aaaacgaatg taaaagaatt actggaggga
     1201 aaagaaaccc tggtaaaagg aatcaaaaac aaagagaaaa agccctacaa tgccgttgta
     1261 aaaattgggg aaaagggata tattgatttt atctcttttt caaaataaac ataaaagccc
     1321 tttaaagagg gcttttatat attaatcaca aatcacttat cacaaatcac aagtgattaa
     1381 tcacaaatca caagtgattt gtgattctta atgatacaat attactatac
//
LOCUS       DBNFCO010000188          912 bp    DNA     linear   BCT 09-APR-2026
DEFINITION  TPA_asm: Streptococcus suis strain DA1_20
            SAMN40446026-rid29426513.guided.166, whole genome shotgun sequence.
ACCESSION   DBNFCO010000188 DBNFCO010000000
VERSION     DBNFCO010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN40446026
            Sequence Read Archive: SRR28339518
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus suis
  ORGANISM  Streptococcus suis
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 912)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 912)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2026) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using the SAUTE guided assembler with
            antimicrobial resistance genes and Stx operons as baits to increase
            sensitivity and specificity for those genes. Note, contigs derived
            from the SAUTE guided assembly may overlap de-novo contigs from
            SKESA, and/or other SAUTE contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names, which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 09-APR-2026
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT003171458.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT003171458.1
            Genome Coverage       :: 66x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/09/2026 16:51:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2025-05-06.build7983
            Genes (total)                     :: 1,996
            CDSs (total)                      :: 1,951
            Genes (coding)                    :: 1,891
            CDSs (with protein)               :: 1,891
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 38
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 29 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 14 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..912
                     /organism="Streptococcus suis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN40446026-rid29426513.guided.166"
                     /strain="DA1_20"
                     /host="swine"
                     /db_xref="taxon:1307"
                     /geo_loc_name="USA"
                     /collection_date="2018"
     gene            105..854
                     /locus_tag="AC1PIV_001996"
     CDS             105..854
                     /locus_tag="AC1PIV_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HIP6612954.1"
                     /translation="MMGSYDSQAKSMAKTAKHLEKRIERLDKVEQPRKETWVKMEAKG
                     ALDTGLHSLFRLQAGQVLMDEVYLFDVPQIGMTFGEKLALVGANGSGKTSFVRKLFRK
                     ELAGYYNPKLKIAYFAQDLINLDEEKTAFENVSCTSLQDRMMILNLLGMLGLSCDKAQ
                     QKVANLSGGERVRLSLAKVLLADANLLILDEPTNFLDMAAIEVLETFLKEYEGSVPLI
                     SHDQQFVETSVHSQWEIVQACLVKKSQENIF"
BASE COUNT          274 a          139 c          226 g          273 t
ORIGIN      
        1 gaacaaatct gccaatcaac cactgcgctg agatgttgac gcgaactttg agaagtgaat
       61 gtggacattt attctaaata tcgtctgagt ggaaagtcag tgccatgatg gggtcctatg
      121 atagtcaagc caagtctatg gccaagactg ccaagcattt ggaaaaacgg atagagcgtt
      181 tggacaaggt tgaacaacct agaaaggaaa cgtgggtaaa gatggaagcg aaaggtgcct
      241 tggatacggg tcttcacagt ctctttcgct tgcaggctgg tcaagttttg atggatgaag
      301 tgtatctatt tgatgtccct cagataggga tgacgtttgg agagaagtta gccttagtgg
      361 gggcgaatgg ttctggaaag actagttttg tccgaaaatt atttaggaaa gaattagcag
      421 gctattataa tcctaagtta aaaattgctt attttgcaca ggatttgata aaccttgatg
      481 aagaaaagac tgcttttgaa aatgttagtt gtacctctct tcaagatagg atgatgattc
      541 tcaatttatt aggtatgtta ggactttctt gcgataaggc tcagcagaag gtagcaaatc
      601 tgtctggtgg tgagcgtgtt cgtctctcct tagctaaggt attgttggcg gatgcaaatc
      661 ttttgatact agatgaaccg acaaattttc tagatatggc agctattgag gttttggaaa
      721 cattcttgaa agaatatgaa ggaagtgtcc ccttgatttc ccatgatcaa cagtttgtgg
      781 aaacatctgt tcacagtcaa tgggagatag tgcaagcttg tctcgtgaag aaatcacaag
      841 aaaatatttt ctgaaaagga ggctctgtct aaaaaatatt ttttgcctgt ggtataataa
      901 gaaggatatt tc
//
