data_PRD_002290
# 
_pdbx_reference_molecule.prd_id                       PRD_002290 
_pdbx_reference_molecule.name                         "Tyrocidine A analogue (DPN)(BE2)F(DPN)NKYV(ORN)L" 
_pdbx_reference_molecule.represent_as                 polymer 
_pdbx_reference_molecule.type                         "Cyclic peptide" 
_pdbx_reference_molecule.type_evidence_code           ? 
_pdbx_reference_molecule.class                        Antibiotic 
_pdbx_reference_molecule.class_evidence_code          ? 
_pdbx_reference_molecule.formula                      "C69 H90 N13 O12" 
_pdbx_reference_molecule.formula_weight               1293.533 
_pdbx_reference_molecule.chem_comp_id                 ? 
_pdbx_reference_molecule.release_status               REL 
_pdbx_reference_molecule.replaces                     ? 
_pdbx_reference_molecule.replaced_by                  ? 
_pdbx_reference_molecule.compound_details             " Tyrocidine kills bacteria by interacting with their cytoplasmic membrane and causing leakage of their intracellular content. It also affects intracellular membranes such as those of mitochondria" 
_pdbx_reference_molecule.description                  ? 
_pdbx_reference_molecule.representative_PDB_id_code   6B35 
# 
_pdbx_reference_entity_list.prd_id          PRD_002290 
_pdbx_reference_entity_list.ref_entity_id   1 
_pdbx_reference_entity_list.component_id    1 
_pdbx_reference_entity_list.type            polymer 
_pdbx_reference_entity_list.details         . 
# 
loop_
_pdbx_reference_entity_poly_link.prd_id 
_pdbx_reference_entity_poly_link.ref_entity_id 
_pdbx_reference_entity_poly_link.link_id 
_pdbx_reference_entity_poly_link.atom_id_1 
_pdbx_reference_entity_poly_link.comp_id_1 
_pdbx_reference_entity_poly_link.entity_seq_num_1 
_pdbx_reference_entity_poly_link.atom_id_2 
_pdbx_reference_entity_poly_link.comp_id_2 
_pdbx_reference_entity_poly_link.entity_seq_num_2 
_pdbx_reference_entity_poly_link.value_order 
_pdbx_reference_entity_poly_link.component_id 
_pdbx_reference_entity_poly_link.details 
_pdbx_reference_entity_poly_link.insert_code_1 
_pdbx_reference_entity_poly_link.insert_code_2 
PRD_002290 1 1  N DPN 1 C LEU 10 sing 1 ? ? ? 
PRD_002290 1 2  C DPN 1 N BE2 2  sing 1 ? ? ? 
PRD_002290 1 3  C BE2 2 N PHE 3  sing 1 ? ? ? 
PRD_002290 1 4  C PHE 3 N DPN 4  sing 1 ? ? ? 
PRD_002290 1 5  C DPN 4 N ASN 5  sing 1 ? ? ? 
PRD_002290 1 6  C ASN 5 N LYS 6  sing 1 ? ? ? 
PRD_002290 1 7  C LYS 6 N TYR 7  sing 1 ? ? ? 
PRD_002290 1 8  C TYR 7 N VAL 8  sing 1 ? ? ? 
PRD_002290 1 9  C VAL 8 N ORN 9  sing 1 ? ? ? 
PRD_002290 1 10 C ORN 9 N LEU 10 sing 1 ? ? ? 
# 
_pdbx_reference_entity_poly.prd_id          PRD_002290 
_pdbx_reference_entity_poly.ref_entity_id   1 
_pdbx_reference_entity_poly.db_code         . 
_pdbx_reference_entity_poly.db_name         . 
_pdbx_reference_entity_poly.type            peptide-like 
# 
_pdbx_reference_entity_sequence.prd_id          PRD_002290 
_pdbx_reference_entity_sequence.ref_entity_id   1 
_pdbx_reference_entity_sequence.type            peptide-like 
_pdbx_reference_entity_sequence.NRP_flag        N 
# 
loop_
_pdbx_reference_entity_poly_seq.prd_id 
_pdbx_reference_entity_poly_seq.ref_entity_id 
_pdbx_reference_entity_poly_seq.num 
_pdbx_reference_entity_poly_seq.mon_id 
_pdbx_reference_entity_poly_seq.parent_mon_id 
_pdbx_reference_entity_poly_seq.hetero 
_pdbx_reference_entity_poly_seq.observed 
PRD_002290 1 1  DPN .   N Y 
PRD_002290 1 2  BE2 .   N Y 
PRD_002290 1 3  PHE PHE N Y 
PRD_002290 1 4  DPN .   N Y 
PRD_002290 1 5  ASN ASN N Y 
PRD_002290 1 6  LYS LYS N Y 
PRD_002290 1 7  TYR TYR N Y 
PRD_002290 1 8  VAL VAL N Y 
PRD_002290 1 9  ORN ALA N Y 
PRD_002290 1 10 LEU LEU N Y 
# 
loop_
_pdbx_prd_audit.prd_id 
_pdbx_prd_audit.date 
_pdbx_prd_audit.processing_site 
_pdbx_prd_audit.action_type 
PRD_002290 2017-10-20 RCSB "Create molecule"    
PRD_002290 2020-08-12 RCSB "Initial release"    
PRD_002290 2023-11-03 PDBE "Other modification" 
# 
_pdbx_reference_entity_src_nat.db_code               NOR00298 
_pdbx_reference_entity_src_nat.db_name               Norine 
_pdbx_reference_entity_src_nat.ordinal               1 
_pdbx_reference_entity_src_nat.organism_scientific   "Brevibacillus brevis" 
_pdbx_reference_entity_src_nat.prd_id                PRD_002290 
_pdbx_reference_entity_src_nat.ref_entity_id         1 
_pdbx_reference_entity_src_nat.source                ? 
_pdbx_reference_entity_src_nat.strain                ? 
_pdbx_reference_entity_src_nat.taxid                 1393 
# 
