data_PRD_000154
# 
_pdbx_reference_molecule.prd_id                       PRD_000154 
_pdbx_reference_molecule.name                         "MINI-GRAMICIDIN A DIMER" 
_pdbx_reference_molecule.represent_as                 polymer 
_pdbx_reference_molecule.type                         Polypeptide 
_pdbx_reference_molecule.type_evidence_code           ? 
_pdbx_reference_molecule.class                        Antibiotic 
_pdbx_reference_molecule.class_evidence_code          ? 
_pdbx_reference_molecule.formula                      "C168 H226 N32 O26" 
_pdbx_reference_molecule.formula_weight               3109.791 
_pdbx_reference_molecule.chem_comp_id                 ? 
_pdbx_reference_molecule.release_status               REL 
_pdbx_reference_molecule.replaces                     ? 
_pdbx_reference_molecule.replaced_by                  ? 
_pdbx_reference_molecule.compound_details             
;GRAMICIDIN IS A HETEROGENEOUS MIXTURE OF SEVERAL COMPOUNDS
INCLUDING GRAMICIDIN A, B AND C WHICH ARE OBTAINED FROM
BACILLUS BREVIS AND CALLED COLLECTIVELY GRAMICIDIN D
HERE, A MODIFIDED GRAMICIDIN A IS REPRESENTED BY TWO SEQUENCES
(SEQRES) AND ONE HET (SIN)
;
_pdbx_reference_molecule.description                  
;THE N-TERMINI OF THE TWO IDENTICAL PEPTIDES, EACH
A TRUNCATED GRAMICIDIN A WERE LINKED BY A SUCCINIC
ACID IN A HEAD-TO-HEAD MANNER.
;
_pdbx_reference_molecule.representative_PDB_id_code   1kqe 
# 
loop_
_pdbx_reference_entity_list.prd_id 
_pdbx_reference_entity_list.ref_entity_id 
_pdbx_reference_entity_list.component_id 
_pdbx_reference_entity_list.type 
_pdbx_reference_entity_list.details 
PRD_000154 1 1 polymer     "CHAIN A PEPTIDE LIKE SEQUENCE RESIDUES 5 TO 16" 
PRD_000154 1 2 polymer     "CHAIN A PEPTIDE LIKE SEQUENCE RESIDUES 5 TO 16" 
PRD_000154 2 3 non-polymer "SUCCINIC ACID"                                  
# 
_pdbx_reference_entity_nonpoly.prd_id          PRD_000154 
_pdbx_reference_entity_nonpoly.ref_entity_id   2 
_pdbx_reference_entity_nonpoly.name            "SUCCINIC ACID" 
_pdbx_reference_entity_nonpoly.chem_comp_id    SIN 
_pdbx_reference_entity_nonpoly.details         ? 
# 
loop_
_pdbx_reference_entity_link.prd_id 
_pdbx_reference_entity_link.link_id 
_pdbx_reference_entity_link.link_class 
_pdbx_reference_entity_link.ref_entity_id_1 
_pdbx_reference_entity_link.entity_seq_num_1 
_pdbx_reference_entity_link.comp_id_1 
_pdbx_reference_entity_link.atom_id_1 
_pdbx_reference_entity_link.ref_entity_id_2 
_pdbx_reference_entity_link.entity_seq_num_2 
_pdbx_reference_entity_link.comp_id_2 
_pdbx_reference_entity_link.atom_id_2 
_pdbx_reference_entity_link.value_order 
_pdbx_reference_entity_link.component_1 
_pdbx_reference_entity_link.component_2 
_pdbx_reference_entity_link.details 
_pdbx_reference_entity_link.nonpoly_res_num_1 
_pdbx_reference_entity_link.nonpoly_res_num_2 
PRD_000154 1 PN 1 1 ALA N 2 ? SIN C4 sing 1 3 ? ? ? 
PRD_000154 2 PN 1 1 ALA N 2 ? SIN C1 sing 2 3 ? ? ? 
# 
loop_
_pdbx_reference_entity_poly_link.prd_id 
_pdbx_reference_entity_poly_link.ref_entity_id 
_pdbx_reference_entity_poly_link.link_id 
_pdbx_reference_entity_poly_link.atom_id_1 
_pdbx_reference_entity_poly_link.comp_id_1 
_pdbx_reference_entity_poly_link.entity_seq_num_1 
_pdbx_reference_entity_poly_link.atom_id_2 
_pdbx_reference_entity_poly_link.comp_id_2 
_pdbx_reference_entity_poly_link.entity_seq_num_2 
_pdbx_reference_entity_poly_link.value_order 
_pdbx_reference_entity_poly_link.component_id 
_pdbx_reference_entity_poly_link.details 
_pdbx_reference_entity_poly_link.insert_code_1 
_pdbx_reference_entity_poly_link.insert_code_2 
PRD_000154 1 1  C ALA 1  N DVA 2  sing 1 ? ? ? 
PRD_000154 1 2  C DVA 2  N VAL 3  sing 1 ? ? ? 
PRD_000154 1 3  C VAL 3  N DVA 4  sing 1 ? ? ? 
PRD_000154 1 4  C DVA 4  N TRP 5  sing 1 ? ? ? 
PRD_000154 1 5  C TRP 5  N DLE 6  sing 1 ? ? ? 
PRD_000154 1 6  C DLE 6  N TRP 7  sing 1 ? ? ? 
PRD_000154 1 7  C TRP 7  N DLE 8  sing 1 ? ? ? 
PRD_000154 1 8  C DLE 8  N TRP 9  sing 1 ? ? ? 
PRD_000154 1 9  C TRP 9  N DLE 10 sing 1 ? ? ? 
PRD_000154 1 10 C DLE 10 N TRP 11 sing 1 ? ? ? 
PRD_000154 1 11 C TRP 11 N ETA 12 sing 1 ? ? ? 
PRD_000154 1 12 C ALA 1  N DVA 2  sing 2 ? ? ? 
PRD_000154 1 13 C DVA 2  N VAL 3  sing 2 ? ? ? 
PRD_000154 1 14 C VAL 3  N DVA 4  sing 2 ? ? ? 
PRD_000154 1 15 C DVA 4  N TRP 5  sing 2 ? ? ? 
PRD_000154 1 16 C TRP 5  N DLE 6  sing 2 ? ? ? 
PRD_000154 1 17 C DLE 6  N TRP 7  sing 2 ? ? ? 
PRD_000154 1 18 C TRP 7  N DLE 8  sing 2 ? ? ? 
PRD_000154 1 19 C DLE 8  N TRP 9  sing 2 ? ? ? 
PRD_000154 1 20 C TRP 9  N DLE 10 sing 2 ? ? ? 
PRD_000154 1 21 C DLE 10 N TRP 11 sing 2 ? ? ? 
PRD_000154 1 22 C TRP 11 N ETA 12 sing 2 ? ? ? 
# 
_pdbx_reference_entity_poly.prd_id          PRD_000154 
_pdbx_reference_entity_poly.ref_entity_id   1 
_pdbx_reference_entity_poly.db_code         NOR00243 
_pdbx_reference_entity_poly.db_name         NOR 
_pdbx_reference_entity_poly.type            peptide-like 
# 
_pdbx_reference_entity_sequence.prd_id          PRD_000154 
_pdbx_reference_entity_sequence.ref_entity_id   1 
_pdbx_reference_entity_sequence.type            peptide-like 
_pdbx_reference_entity_sequence.NRP_flag        Y 
# 
loop_
_pdbx_reference_entity_poly_seq.prd_id 
_pdbx_reference_entity_poly_seq.ref_entity_id 
_pdbx_reference_entity_poly_seq.num 
_pdbx_reference_entity_poly_seq.mon_id 
_pdbx_reference_entity_poly_seq.parent_mon_id 
_pdbx_reference_entity_poly_seq.hetero 
_pdbx_reference_entity_poly_seq.observed 
PRD_000154 1 1  ALA ALA N Y 
PRD_000154 1 2  DVA VAL N Y 
PRD_000154 1 3  VAL VAL N Y 
PRD_000154 1 4  DVA VAL N Y 
PRD_000154 1 5  TRP TRP N Y 
PRD_000154 1 6  DLE LEU N Y 
PRD_000154 1 7  TRP TRP N Y 
PRD_000154 1 8  DLE LEU N Y 
PRD_000154 1 9  TRP TRP N Y 
PRD_000154 1 10 DLE LEU N Y 
PRD_000154 1 11 TRP TRP N Y 
PRD_000154 1 12 ETA ?   N Y 
# 
_pdbx_reference_entity_src_nat.prd_id                PRD_000154 
_pdbx_reference_entity_src_nat.ref_entity_id         1 
_pdbx_reference_entity_src_nat.ordinal               1 
_pdbx_reference_entity_src_nat.taxid                 1393 
_pdbx_reference_entity_src_nat.organism_scientific   "bacillus brevis" 
_pdbx_reference_entity_src_nat.source                ? 
_pdbx_reference_entity_src_nat.db_code               NOR00245 
_pdbx_reference_entity_src_nat.db_name               Norine 
_pdbx_reference_entity_src_nat.strain                ? 
# 
loop_
_pdbx_prd_audit.prd_id 
_pdbx_prd_audit.date 
_pdbx_prd_audit.processing_site 
_pdbx_prd_audit.action_type 
PRD_000154 2012-02-10 RCSB "Create molecule"    
PRD_000154 2012-07-09 PDBE "Other modification" 
PRD_000154 2012-12-12 RCSB "Initial release"    
PRD_000154 2013-06-03 RCSB "Other modification" 
PRD_000154 2017-05-04 RCSB "Other modification" 
PRD_000154 2023-09-20 PDBE "Modify audit"       
# 
