data_PRD_000227
# 
_pdbx_reference_molecule.prd_id                       PRD_000227 
_pdbx_reference_molecule.name                         "VIRGINIAMYCIN S1" 
_pdbx_reference_molecule.represent_as                 polymer 
_pdbx_reference_molecule.type                         "Cyclic peptide" 
_pdbx_reference_molecule.type_evidence_code           ? 
_pdbx_reference_molecule.class                        "Antibiotic, Antimicrobial" 
_pdbx_reference_molecule.class_evidence_code          ? 
_pdbx_reference_molecule.formula                      "C43 H49 N7 O10" 
_pdbx_reference_molecule.formula_weight               823.890 
_pdbx_reference_molecule.chem_comp_id                 ? 
_pdbx_reference_molecule.release_status               REL 
_pdbx_reference_molecule.replaces                     ? 
_pdbx_reference_molecule.replaced_by                  ? 
_pdbx_reference_molecule.compound_details             ? 
_pdbx_reference_molecule.description                  
;VIRGINIAMYCIN S1 IS A CYLIC HEPTAPEPTIDE. THE RING IS GENERATED BY LINKING RESIDUE 2 SIDE-CHAIN AND RESIDUE 7
MAIN-CHAIN.
;
_pdbx_reference_molecule.representative_PDB_id_code   1yit 
# 
_pdbx_reference_entity_list.prd_id          PRD_000227 
_pdbx_reference_entity_list.ref_entity_id   1 
_pdbx_reference_entity_list.component_id    1 
_pdbx_reference_entity_list.type            polymer 
_pdbx_reference_entity_list.details         "PEPTIDE LIKE SEQUENCE RESIDUES 1 TO 7" 
# 
loop_
_pdbx_reference_entity_poly_link.prd_id 
_pdbx_reference_entity_poly_link.ref_entity_id 
_pdbx_reference_entity_poly_link.link_id 
_pdbx_reference_entity_poly_link.atom_id_1 
_pdbx_reference_entity_poly_link.comp_id_1 
_pdbx_reference_entity_poly_link.entity_seq_num_1 
_pdbx_reference_entity_poly_link.atom_id_2 
_pdbx_reference_entity_poly_link.comp_id_2 
_pdbx_reference_entity_poly_link.entity_seq_num_2 
_pdbx_reference_entity_poly_link.value_order 
_pdbx_reference_entity_poly_link.component_id 
_pdbx_reference_entity_poly_link.details 
_pdbx_reference_entity_poly_link.insert_code_1 
_pdbx_reference_entity_poly_link.insert_code_2 
PRD_000227 1 1 C   MHW 1 N THR 2 sing 1 ? ? ? 
PRD_000227 1 2 C   THR 2 N DBB 3 sing 1 ? ? ? 
PRD_000227 1 3 OG1 THR 2 C 004 7 sing 1 ? ? ? 
PRD_000227 1 4 C   DBB 3 N PRO 4 sing 1 ? ? ? 
PRD_000227 1 5 C   PRO 4 N MEA 5 sing 1 ? ? ? 
PRD_000227 1 6 C   MEA 5 N MHV 6 sing 1 ? ? ? 
PRD_000227 1 7 C   MHV 6 N 004 7 sing 1 ? ? ? 
# 
_pdbx_reference_entity_poly.prd_id          PRD_000227 
_pdbx_reference_entity_poly.ref_entity_id   1 
_pdbx_reference_entity_poly.db_code         NOR00679 
_pdbx_reference_entity_poly.db_name         NOR 
_pdbx_reference_entity_poly.type            peptide-like 
# 
_pdbx_reference_entity_sequence.prd_id          PRD_000227 
_pdbx_reference_entity_sequence.ref_entity_id   1 
_pdbx_reference_entity_sequence.type            peptide-like 
_pdbx_reference_entity_sequence.NRP_flag        Y 
# 
loop_
_pdbx_reference_entity_poly_seq.prd_id 
_pdbx_reference_entity_poly_seq.ref_entity_id 
_pdbx_reference_entity_poly_seq.num 
_pdbx_reference_entity_poly_seq.mon_id 
_pdbx_reference_entity_poly_seq.parent_mon_id 
_pdbx_reference_entity_poly_seq.hetero 
_pdbx_reference_entity_poly_seq.observed 
PRD_000227 1 1 MHW ?   N Y 
PRD_000227 1 2 THR THR N Y 
PRD_000227 1 3 DBB ALA N Y 
PRD_000227 1 4 PRO PRO N Y 
PRD_000227 1 5 MEA PHE N Y 
PRD_000227 1 6 MHV ?   N Y 
PRD_000227 1 7 004 GLY N Y 
# 
loop_
_pdbx_reference_entity_src_nat.prd_id 
_pdbx_reference_entity_src_nat.ref_entity_id 
_pdbx_reference_entity_src_nat.ordinal 
_pdbx_reference_entity_src_nat.taxid 
_pdbx_reference_entity_src_nat.organism_scientific 
_pdbx_reference_entity_src_nat.source 
_pdbx_reference_entity_src_nat.db_code 
_pdbx_reference_entity_src_nat.db_name 
_pdbx_reference_entity_src_nat.strain 
PRD_000227 1 1 1961  "Streptomyces virginiae"      ?     NOR00679 Norine ? 
PRD_000227 1 2 68212 "Streptomyces graminofaciens" Merck ?        ?      ? 
PRD_000227 1 3 1961  "Streptomyces virginiae"      Merck ?        ?      ? 
PRD_000227 1 4 68248 "Streptomyces ostreogriseus"  Merck ?        ?      ? 
# 
loop_
_pdbx_prd_audit.prd_id 
_pdbx_prd_audit.date 
_pdbx_prd_audit.processing_site 
_pdbx_prd_audit.action_type 
PRD_000227 2012-02-08 RCSB "Create molecule"    
PRD_000227 2012-07-09 PDBE "Other modification" 
PRD_000227 2012-07-31 RCSB "Other modification" 
PRD_000227 2012-11-28 RCSB "Modify class"       
PRD_000227 2012-12-12 RCSB "Initial release"    
PRD_000227 2013-06-03 RCSB "Other modification" 
PRD_000227 2017-05-04 RCSB "Other modification" 
PRD_000227 2020-07-29 RCSB "Other modification" 
PRD_000227 2023-09-20 PDBE "Modify audit"       
# 
