data_GRP
#

_chem_comp.id                                   GRP
_chem_comp.name                                 
;
[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2R,3S,5S,6R)-3-hydroxy-5-{[(1Z)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}-6-methyltetrahydro-2H-pyran-2-yl dihydrogen diphosphate
;

_chem_comp.type                                 NON-POLYMER
_chem_comp.pdbx_type                            HETAIN
_chem_comp.formula                              "C24 H34 N7 O18 P3"
_chem_comp.mon_nstd_parent_comp_id              ?
_chem_comp.pdbx_synonyms                        ?
_chem_comp.pdbx_formal_charge                   0
_chem_comp.pdbx_initial_date                    2008-07-18
_chem_comp.pdbx_modified_date                   2013-06-06
_chem_comp.pdbx_ambiguous_flag                  N
_chem_comp.pdbx_release_status                  OBS
_chem_comp.pdbx_replaced_by                     ?
_chem_comp.pdbx_replaces                        ?
_chem_comp.formula_weight                       801.484
_chem_comp.one_letter_code                      ?
_chem_comp.three_letter_code                    GRP
_chem_comp.pdbx_model_coordinates_details       ?
_chem_comp.pdbx_model_coordinates_missing_flag  N
_chem_comp.pdbx_ideal_coordinates_details       Corina
_chem_comp.pdbx_ideal_coordinates_missing_flag  N
_chem_comp.pdbx_model_coordinates_db_code       3DR7
_chem_comp.pdbx_subcomponent_list               ?
_chem_comp.pdbx_processing_site                 RCSB
#   #
loop_
_chem_comp_atom.comp_id
_chem_comp_atom.atom_id
_chem_comp_atom.alt_atom_id
_chem_comp_atom.type_symbol
_chem_comp_atom.charge
_chem_comp_atom.pdbx_align
_chem_comp_atom.pdbx_aromatic_flag
_chem_comp_atom.pdbx_leaving_atom_flag
_chem_comp_atom.pdbx_stereo_config
_chem_comp_atom.model_Cartn_x
_chem_comp_atom.model_Cartn_y
_chem_comp_atom.model_Cartn_z
_chem_comp_atom.pdbx_model_Cartn_x_ideal
_chem_comp_atom.pdbx_model_Cartn_y_ideal
_chem_comp_atom.pdbx_model_Cartn_z_ideal
_chem_comp_atom.pdbx_component_atom_id
_chem_comp_atom.pdbx_component_comp_id
_chem_comp_atom.pdbx_ordinal
GRP  N4A   N4A     N  0  1  N  N  N  15.953  -2.774   -4.088  -4.021  -0.031   1.838  N4A   GRP   1  
GRP  C4G   C4G     C  0  1  N  N  S  17.294  -2.678   -4.620  -4.162   1.048   0.857  C4G   GRP   2  
GRP  C5G   C5G     C  0  1  N  N  R  18.274  -3.343   -3.672  -3.310   0.733  -0.375  C5G   GRP   3  
GRP  C6G   C6G     C  0  1  N  N  N  17.968  -4.820   -3.429  -3.819  -0.552  -1.032  C6G   GRP   4  
GRP  O5G   O5G     O  0  1  N  N  N  19.657  -3.158   -3.973  -3.403   1.813  -1.306  O5G   GRP   5  
GRP  C3G   C3G     C  0  1  N  N  N  17.583  -1.191   -4.782  -3.685   2.367   1.474  C3G   GRP   6  
GRP  C2G   C2G     C  0  1  N  N  S  19.079  -0.962   -4.839  -3.763   3.471   0.415  C2G   GRP   7  
GRP  O2G   O2G     O  0  1  N  N  N  19.434  -0.165   -5.965  -5.123   3.657   0.019  O2G   GRP   8  
GRP  C1G   C1G     C  0  1  N  N  R  19.896  -2.224   -5.008  -2.927   3.062  -0.800  C1G   GRP   9  
GRP  O1G   O1G     O  0  1  N  N  N  21.181  -1.666   -4.831  -1.558   2.928  -0.413  O1G   GRP  10  
GRP  P2    P2      P  0  1  N  N  N  22.474  -1.954   -5.712  -0.331   3.203  -1.420  P2    GRP  11  
GRP  O3P   O3P     O  0  1  N  N  N  22.606  -3.446   -5.825  -0.457   4.562  -1.992  O3P   GRP  12  
GRP  O4P   O4P     O  0  1  N  N  N  23.530  -1.153   -4.987  -0.358   2.116  -2.607  O4P   GRP  13  
GRP  OPP   OPP     O  0  1  N  N  N  22.077  -1.240   -7.102   1.059   3.085  -0.616  OPP   GRP  14  
GRP  P     P       P  0  1  N  N  N  23.091  -1.036   -8.331   2.555   3.615  -0.886  P     GRP  15  
GRP  O1P   O1P     O  0  1  N  N  N  24.484  -1.441   -7.956   2.658   5.167  -0.470  O1P   GRP  16  
GRP  O2P   O2P     O  0  1  N  N  N  22.913   0.366   -8.811   2.879   3.467  -2.323  O2P   GRP  17  
GRP  O5*   "O5'"   O  0  1  N  N  N  22.509  -1.992   -9.489   3.596   2.755  -0.010  O5*   GRP  18  
GRP  C5*   "C5'"   C  0  1  N  N  N  22.692  -3.401   -9.479   5.012   2.913  -0.107  C5*   GRP  19  
GRP  C4*   "C4'"   C  0  1  N  N  R  23.214  -3.807  -10.835   5.701   1.946   0.859  C4*   GRP  20  
GRP  O4*   "O4'"   O  0  1  N  N  N  22.308  -3.345  -11.854   5.479   0.591   0.435  O4*   GRP  21  
GRP  C3*   "C3'"   C  0  1  N  N  S  24.543  -3.109  -11.090   7.223   2.190   0.848  C3*   GRP  22  
GRP  O3*   "O3'"   O  0  1  N  N  N  25.396  -4.062  -11.729   7.679   2.559   2.151  O3*   GRP  23  
GRP  C2*   "C2'"   C  0  1  N  N  R  24.224  -2.027  -12.110   7.823   0.827   0.427  C2*   GRP  24  
GRP  O2*   "O2'"   O  0  1  N  N  N  25.314  -1.866  -13.018   8.993   0.527   1.189  O2*   GRP  25  
GRP  C1*   "C1'"   C  0  1  N  N  R  23.017  -2.598  -12.827   6.668  -0.156   0.771  C1*   GRP  26  
GRP  N9    N9      N  0  1  Y  N  N  22.166  -1.535  -13.392   6.762  -1.371  -0.043  N9    GRP  27  
GRP  C8    C8      C  0  1  Y  N  N  21.343  -0.739  -12.715   6.176  -1.576  -1.258  C8    GRP  28  
GRP  N7    N7      N  0  1  Y  N  N  20.759   0.105  -13.587   6.469  -2.766  -1.694  N7    GRP  29  
GRP  C4    C4      C  0  1  Y  N  N  22.119  -1.212  -14.686   7.458  -2.506   0.275  C4    GRP  30  
GRP  C5    C5      C  0  1  Y  N  N  21.223  -0.165  -14.822   7.257  -3.394  -0.788  C5    GRP  31  
GRP  C6    C6      C  0  1  N  N  N  20.986   0.367  -16.090   7.865  -4.670  -0.728  C6    GRP  32  
GRP  O6    O6      O  0  1  N  N  N  20.186   1.285  -16.316   7.722  -5.473  -1.634  O6    GRP  33  
GRP  N3    N3      N  0  1  N  N  N  22.748  -1.711  -15.773   8.214  -2.876   1.315  N3    GRP  34  
GRP  C2    C2      C  0  1  N  N  N  22.512  -1.177  -16.984   8.777  -4.063   1.357  C2    GRP  35  
GRP  N1    N1      N  0  1  N  N  N  21.640  -0.162  -17.130   8.609  -4.976   0.358  N1    GRP  36  
GRP  N2    N2      N  0  1  N  N  N  23.134  -1.643  -18.098   9.545  -4.398   2.444  N2    GRP  37  
GRP  H4G   H4G     H  0  1  N  N  N  17.350  -3.167   -5.604  -5.207   1.140   0.563  H4G   GRP  38  
GRP  H5G   H5G     H  0  1  N  N  N  18.107  -2.855   -2.700  -2.271   0.600  -0.075  H5G   GRP  39  
GRP  H6G   H6G     H  0  1  N  N  N  18.712  -5.240   -2.736  -4.858  -0.419  -1.333  H6G   GRP  40  
GRP  H6GA  H6GA    H  0  0  N  N  N  16.963  -4.919   -2.992  -3.212  -0.776  -1.910  H6GA  GRP  41  
GRP  H6GB  H6GB    H  0  0  N  N  N  18.008  -5.364   -4.384  -3.749  -1.376  -0.322  H6GB  GRP  42  
GRP  H3G   H3G     H  0  1  N  N  N  17.122  -0.829   -5.713  -4.323   2.626   2.319  H3G   GRP  43  
GRP  H3GA  H3GA    H  0  0  N  N  N  17.162  -0.642   -3.927  -2.655   2.258   1.814  H3GA  GRP  44  
GRP  H2G   H2G     H  0  1  N  N  N  19.394  -0.461   -3.912  -3.374   4.401   0.829  H2G   GRP  45  
GRP  HO2G  HO2G    H  0  0  N  N  N  20.375  -0.036   -5.978  -5.248   4.343  -0.651  HO2G  GRP  46  
GRP  H1G   H1G     H  0  1  N  N  N  19.755  -2.656   -6.010  -3.013   3.824  -1.574  H1G   GRP  47  
GRP  HO4P  HO4P    H  0  0  N  N  N  24.205  -1.738   -4.664  -0.280   1.201  -2.305  HO4P  GRP  48  
GRP  HO1P  HO1P    H  0  0  N  N  N  25.074  -0.708   -8.087   2.458   5.339   0.460  HO1P  GRP  49  
GRP  H5*   "H5'"   H  0  1  N  N  N  23.417  -3.679   -8.700   5.333   2.698  -1.126  H5*   GRP  50  
GRP  H5*A  "H5'A"  H  0  0  N  N  N  21.733  -3.902   -9.282   5.282   3.937   0.151  H5*A  GRP  51  
GRP  H4*   "H4'"   H  0  1  N  N  N  23.345  -4.898  -10.882   5.310   2.088   1.866  H4*   GRP  52  
GRP  H3*   "H3'"   H  0  1  N  N  N  24.970  -2.690  -10.167   7.480   2.961   0.122  H3*   GRP  53  
GRP  HO3*  "HO3'"  H  0  0  N  N  N  26.240  -3.664  -11.906   8.630   2.725   2.202  HO3*  GRP  54  
GRP  H2*   "H2'"   H  0  1  N  N  N  23.966  -1.084  -11.606   8.041   0.811  -0.641  H2*   GRP  55  
GRP  HO2*  "HO2'"  H  0  0  N  N  N  25.103  -1.188  -13.650   9.710   1.166   1.076  HO2*  GRP  56  
GRP  H1*   "H1'"   H  0  1  N  N  N  23.363  -3.258  -13.636   6.680  -0.402   1.833  H1*   GRP  57  
GRP  H8    H8      H  0  1  N  N  N  21.172  -0.765  -11.649   5.561  -0.857  -1.780  H8    GRP  58  
GRP  HN1   HN1     H  0  1  N  N  N  21.476   0.208  -18.044   9.036  -5.844   0.422  HN1   GRP  59  
GRP  HN2   HN2     H  0  1  N  N  N  23.784  -2.400  -18.028   9.665  -3.763   3.167  HN2   GRP  60  
GRP  HN2A  HN2A    H  0  0  N  N  N  22.942  -1.229  -18.988   9.967  -5.271   2.489  HN2A  GRP  61  
GRP  C17   C17     C  0  1  N  N  N  14.982  -2.255   -4.816  -5.034  -0.784   2.120  C17   GRP  62  
GRP  C18   C18     C  0  1  Y  N  N  14.158  -1.485   -5.865  -6.374  -0.442   1.607  C18   GRP  63  
GRP  N71   N71     N  0  1  Y  N  N  14.031   0.379   -8.314  -8.864   0.193   0.650  N71   GRP  64  
GRP  C19   C19     C  0  1  Y  N  N  12.731  -0.152   -7.682  -8.221   1.081   1.380  C19   GRP  65  
GRP  C20   C20     C  0  1  Y  N  N  12.795  -1.084   -6.458  -6.958   0.805   1.886  C20   GRP  66  
GRP  C21   C21     C  0  1  Y  N  N  15.458  -0.954   -6.497  -7.098  -1.347   0.822  C21   GRP  67  
GRP  C22   C22     C  0  1  Y  N  N  15.395  -0.022   -7.721  -8.347  -0.986   0.362  C22   GRP  68  
GRP  O14   O14     O  0  1  N  N  N  11.430  -1.375   -6.143  -6.300   1.723   2.638  O14   GRP  69  
GRP  C23   C23     C  0  1  N  N  N  11.367   0.249   -8.274  -8.866   2.411   1.674  C23   GRP  70  
GRP  C24   C24     C  0  1  N  N  N  16.759  -0.423   -7.129  -6.520  -2.697   0.484  C24   GRP  71  
GRP  H25   H25     H  0  1  N  N  N  14.154  -2.696   -4.281  -4.898  -1.664   2.732  H25   GRP  72  
GRP  H26   H26     H  0  1  N  N  N  16.307   0.351   -8.164  -8.913  -1.681  -0.240  H26   GRP  73  
GRP  H27   H27     H  0  1  N  N  N  10.860  -0.928   -6.758  -6.533   1.703   3.576  H27   GRP  74  
GRP  H28   H28     H  0  1  N  N  N  11.522   0.913   -9.137  -9.444   2.339   2.595  H28   GRP  75  
GRP  H29   H29     H  0  1  N  N  N  10.829  -0.654   -8.599  -8.094   3.172   1.788  H29   GRP  76  
GRP  H30   H30     H  0  1  N  N  N  10.775   0.774   -7.509  -9.526   2.684   0.851  H30   GRP  77  
GRP  O15   O15     O  0  1  N  N  N  17.013   0.226   -7.966  -7.449  -3.425  -0.321  O15   GRP  78  
GRP  P3    P3      P  0  1  N  N  N  17.245  -0.310   -8.728  -7.160  -4.912  -0.867  P3    GRP  79  
GRP  O16   O16     O  0  1  N  N  N  16.282  -0.690   -9.610  -8.467  -5.470  -1.623  O16   GRP  80  
GRP  O17   O17     O  0  1  N  N  N  18.536  -0.690   -8.925  -5.921  -4.874  -1.895  O17   GRP  81  
GRP  H31   H31     H  0  1  N  N  N  18.707  -0.760   -9.857  -6.067  -4.310  -2.667  H31   GRP  82  
GRP  H32   H32     H  0  1  N  N  N  16.658  -0.759  -10.480  -8.365  -6.363  -1.979  H32   GRP  83  
GRP  O18   O18     O  0  1  N  N  N  17.703  -0.476  -10.242  -6.831  -5.800   0.270  O18   GRP  84  
GRP  H33   H33     H  0  1  N  N  N  17.249   0.078   -6.281  -5.588  -2.566  -0.065  H33   GRP  85  
GRP  H34   H34     H  0  1  N  N  N  17.302  -1.349   -7.371  -6.325  -3.250   1.403  H34   GRP  86  
#   #
loop_
_chem_comp_bond.comp_id
_chem_comp_bond.atom_id_1
_chem_comp_bond.atom_id_2
_chem_comp_bond.value_order
_chem_comp_bond.pdbx_aromatic_flag
_chem_comp_bond.pdbx_stereo_config
_chem_comp_bond.pdbx_ordinal
GRP  C4G  N4A   SING  N  N   1  
GRP  C4G  C5G   SING  N  N   2  
GRP  C4G  H4G   SING  N  N   3  
GRP  C5G  C6G   SING  N  N   4  
GRP  C5G  H5G   SING  N  N   5  
GRP  C6G  H6G   SING  N  N   6  
GRP  C6G  H6GA  SING  N  N   7  
GRP  C6G  H6GB  SING  N  N   8  
GRP  O5G  C5G   SING  N  N   9  
GRP  C3G  C4G   SING  N  N  10  
GRP  C3G  H3G   SING  N  N  11  
GRP  C3G  H3GA  SING  N  N  12  
GRP  C2G  C3G   SING  N  N  13  
GRP  C2G  H2G   SING  N  N  14  
GRP  O2G  C2G   SING  N  N  15  
GRP  O2G  HO2G  SING  N  N  16  
GRP  C1G  O5G   SING  N  N  17  
GRP  C1G  C2G   SING  N  N  18  
GRP  C1G  O1G   SING  N  N  19  
GRP  C1G  H1G   SING  N  N  20  
GRP  P2   O1G   SING  N  N  21  
GRP  P2   O4P   SING  N  N  22  
GRP  O3P  P2    DOUB  N  N  23  
GRP  O4P  HO4P  SING  N  N  24  
GRP  OPP  P2    SING  N  N  25  
GRP  P    OPP   SING  N  N  26  
GRP  P    O1P   SING  N  N  27  
GRP  O1P  HO1P  SING  N  N  28  
GRP  O2P  P     DOUB  N  N  29  
GRP  O5*  P     SING  N  N  30  
GRP  O5*  C5*   SING  N  N  31  
GRP  C5*  H5*   SING  N  N  32  
GRP  C5*  H5*A  SING  N  N  33  
GRP  C4*  C5*   SING  N  N  34  
GRP  C4*  H4*   SING  N  N  35  
GRP  O4*  C4*   SING  N  N  36  
GRP  C3*  C4*   SING  N  N  37  
GRP  C3*  H3*   SING  N  N  38  
GRP  O3*  C3*   SING  N  N  39  
GRP  O3*  HO3*  SING  N  N  40  
GRP  C2*  C3*   SING  N  N  41  
GRP  C2*  H2*   SING  N  N  42  
GRP  O2*  C2*   SING  N  N  43  
GRP  O2*  HO2*  SING  N  N  44  
GRP  C1*  O4*   SING  N  N  45  
GRP  C1*  C2*   SING  N  N  46  
GRP  C1*  H1*   SING  N  N  47  
GRP  N9   C1*   SING  N  N  48  
GRP  N9   C8    SING  Y  N  49  
GRP  C8   H8    SING  N  N  50  
GRP  N7   C8    DOUB  Y  N  51  
GRP  C4   N9    SING  Y  N  52  
GRP  C5   N7    SING  Y  N  53  
GRP  C5   C4    DOUB  Y  N  54  
GRP  C6   C5    SING  N  N  55  
GRP  O6   C6    DOUB  N  N  56  
GRP  N3   C4    SING  N  N  57  
GRP  C2   N3    DOUB  N  N  58  
GRP  N1   C6    SING  N  N  59  
GRP  N1   C2    SING  N  N  60  
GRP  N1   HN1   SING  N  N  61  
GRP  N2   C2    SING  N  N  62  
GRP  N2   HN2   SING  N  N  63  
GRP  N2   HN2A  SING  N  N  64  
GRP  N4A  C17   DOUB  N  N  65  
GRP  C17  C18   SING  N  N  66  
GRP  C20  C18   SING  Y  N  67  
GRP  C18  C21   DOUB  Y  N  68  
GRP  N71  C19   SING  Y  N  69  
GRP  C19  C20   DOUB  Y  N  70  
GRP  C21  C22   SING  Y  N  71  
GRP  N71  C22   DOUB  Y  N  72  
GRP  C20  O14   SING  N  N  73  
GRP  C19  C23   SING  N  N  74  
GRP  C21  C24   SING  N  N  75  
GRP  C17  H25   SING  N  N  76  
GRP  C22  H26   SING  N  N  77  
GRP  O14  H27   SING  N  N  78  
GRP  C23  H28   SING  N  N  79  
GRP  C23  H29   SING  N  N  80  
GRP  C23  H30   SING  N  N  81  
GRP  C24  O15   SING  N  N  82  
GRP  O15  P3    SING  N  N  83  
GRP  P3   O16   SING  N  N  84  
GRP  P3   O17   SING  N  N  85  
GRP  O17  H31   SING  N  N  86  
GRP  O16  H32   SING  N  N  87  
GRP  P3   O18   DOUB  N  N  88  
GRP  C24  H33   SING  N  N  89  
GRP  C24  H34   SING  N  N  90  
#   #
loop_
_pdbx_chem_comp_descriptor.comp_id
_pdbx_chem_comp_descriptor.type
_pdbx_chem_comp_descriptor.program
_pdbx_chem_comp_descriptor.program_version
_pdbx_chem_comp_descriptor.descriptor
GRP  SMILES            ACDLabs               12.01  "O=C5NC(=Nc1c5ncn1C2OC(C(O)C2O)COP(=O)(OP(=O)(OC4OC(C(/N=C\c3c(cnc(c3O)C)COP(=O)(O)O)CC4O)C)O)O)N"  
GRP  InChI             InChI                 1.03   "InChI=1S/C24H34N7O18P3/c1-9-17(33)12(11(4-26-9)6-44-50(37,38)39)5-27-13-3-14(32)23(46-10(13)2)48-52(42,43)49-51(40,41)45-7-15-18(34)19(35)22(47-15)31-8-28-16-20(31)29-24(25)30-21(16)36/h4-5,8,10,13-15,18-19,22-23,32-35H,3,6-7H2,1-2H3,(H,40,41)(H,42,43)(H2,37,38,39)(H3,25,29,30,36)/b27-5-/t10-,13+,14+,15-,18-,19-,22-,23-/m1/s1"  
GRP  InChIKey          InChI                 1.03   NJFQSOKHMSGVAE-UQPWFEBUSA-N  
GRP  SMILES_CANONICAL  CACTVS                3.370  "C[C@H]1O[C@H](O[P](O)(=O)O[P](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n3cnc4C(=O)NC(=Nc34)N)[C@@H](O)C[C@@H]1N=Cc5c(O)c(C)ncc5CO[P](O)(O)=O"  
GRP  SMILES            CACTVS                3.370  "C[CH]1O[CH](O[P](O)(=O)O[P](O)(=O)OC[CH]2O[CH]([CH](O)[CH]2O)n3cnc4C(=O)NC(=Nc34)N)[CH](O)C[CH]1N=Cc5c(O)c(C)ncc5CO[P](O)(O)=O"  
GRP  SMILES_CANONICAL  "OpenEye OEToolkits"  1.7.6  "Cc1c(c(c(cn1)COP(=O)(O)O)/C=N\[C@H]2C[C@@H]([C@H](O[C@@H]2C)O[P@](=O)(O)O[P@@](=O)(O)OC[C@@H]3[C@H]([C@H]([C@@H](O3)n4cnc5c4N=C(NC5=O)N)O)O)O)O"  
GRP  SMILES            "OpenEye OEToolkits"  1.7.6  "Cc1c(c(c(cn1)COP(=O)(O)O)C=NC2CC(C(OC2C)OP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)n4cnc5c4N=C(NC5=O)N)O)O)O)O"  
#   #
loop_
_pdbx_chem_comp_identifier.comp_id
_pdbx_chem_comp_identifier.type
_pdbx_chem_comp_identifier.program
_pdbx_chem_comp_identifier.program_version
_pdbx_chem_comp_identifier.identifier
GRP  "SYSTEMATIC NAME"  ACDLabs               12.01  "[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2R,3S,5S,6R)-3-hydroxy-5-[(Z)-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)amino]-6-methyltetrahydro-2H-pyran-2-yl dihydrogen diphosphate (non-preferred name)"  
GRP  "SYSTEMATIC NAME"  "OpenEye OEToolkits"  1.7.6  "[[(2R,3S,4R,5R)-5-(2-azanyl-6-oxidanylidene-1H-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2R,3S,5S,6R)-6-methyl-5-[(Z)-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]-3-oxidanyl-oxan-2-yl] hydrogen phosphate"  
#   #
loop_
_pdbx_chem_comp_audit.comp_id
_pdbx_chem_comp_audit.action_type
_pdbx_chem_comp_audit.date
_pdbx_chem_comp_audit.processing_site
GRP  "Create component"      2008-07-18  RCSB  
GRP  "Modify aromatic_flag"  2011-06-04  RCSB  
GRP  "Modify descriptor"     2011-06-04  RCSB  
GRP  "Obsolete component"    2013-06-06  RCSB  
##
