<?xml version="1.0" ?>
<wwPDB-validation-information xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:noNamespaceSchemaLocation="http://wwpdb.org/validation/schema/wwpdb_validation_v6.06.xsd">
	<Entry percentilebins="all,2.0,xray" attemptedValidationSteps="molprobity,validation-pack,mogul,buster-report,percentiles,writexml" PDB-deposition-date="1991-06-04" PDB-revision-date="2024-02-07" PDB-revision-number="5" protein-DNA-RNA-entities="1" PDB-resolution="2.00" PDB-resolution-low="8.00" PDB-R="0.1570" PDB-Rfree="NotAvailable" pdbid="1D44" extended_pdbid="1D44" num-H-reduce="294" clashscore="39.36" RestypesNotcheckedForBondAngleGeometry="MG,HT" bonds_rmsz="1.24" num_bonds_rmsz="544" angles_rmsz="2.21" num_angles_rmsz="836" ligands-for-buster-report="yes" absolute-percentile-clashscore="1.7" numPDBids-absolute-percentile-clashscore="190562" relative-percentile-clashscore="0.7" numPDBids-relative-percentile-clashscore="11152" low-resol-relative-percentile-clashscore="2.0" high-resol-relative-percentile-clashscore="2.0" XMLcreationDate="Mar  1, 2026 -- 10:28 PM UTC"/>
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		<angle-outlier atom0="C5'" atom1="C4'" atom2="O4'" obs="119.940" z="7.03" mean="109.400" stdev="1.500"/>
	</ModelledSubgroup>
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		<angle-outlier atom0="P" atom1="O3'" atom2="C3'" obs="135.914" z="10.48" mean="120.200" stdev="1.500" link="yes"/>
		<angle-outlier atom0="O5'" atom1="P" atom2="OP1" obs="124.108" z="5.04" mean="109.000" stdev="3.000"/>
		<angle-outlier atom0="P" atom1="O5'" atom2="C5'" obs="134.750" z="9.83" mean="120.000" stdev="1.500"/>
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		<angle-outlier atom0="O5'" atom1="C5'" atom2="C4'" obs="102.610" z="-5.46" mean="110.800" stdev="1.500"/>
	</ModelledSubgroup>
	<ModelledSubgroup num-H-reduce="11" model="1" chain="A" resnum="5" said="A" ent="1" seq="5" icode=" " resname="DA" altcode=" ">
		<angle-outlier atom0="P" atom1="O3'" atom2="C3'" obs="132.812" z="8.41" mean="120.200" stdev="1.500" link="yes"/>
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	<ModelledSubgroup num-H-reduce="11" model="1" chain="A" resnum="6" said="A" ent="1" seq="6" icode=" " resname="DA" altcode=" ">
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		<clash atom="C2" dist="2.46" clashmag="0.51" cid="9"/>
		<angle-outlier atom0="P" atom1="O3'" atom2="C3'" obs="130.303" z="6.74" mean="120.200" stdev="1.500" link="yes"/>
	</ModelledSubgroup>
	<ModelledSubgroup num-H-reduce="12" model="1" chain="A" resnum="7" said="A" ent="1" seq="7" icode=" " resname="DT" altcode=" ">
		<bond-outlier atom0="O3'" atom1="P" obs="1.507" z="-6.66" mean="1.607" stdev="0.015" link="yes"/>
		<angle-outlier atom0="P" atom1="O3'" atom2="C3'" obs="136.679" z="10.99" mean="120.200" stdev="1.500" link="yes"/>
	</ModelledSubgroup>
	<ModelledSubgroup num-H-reduce="12" model="1" chain="A" resnum="8" said="A" ent="1" seq="8" icode=" " resname="DT" altcode=" ">
		<clash atom="H2''" dist="2.18" clashmag="0.44" cid="26"/>
		<angle-outlier atom0="P" atom1="O3'" atom2="C3'" obs="137.617" z="11.61" mean="120.200" stdev="1.500" link="yes"/>
		<angle-outlier atom0="C2'" atom1="C3'" atom2="O3'" obs="119.945" z="5.63" mean="111.500" stdev="1.500"/>
	</ModelledSubgroup>
	<ModelledSubgroup num-H-reduce="11" model="1" chain="A" resnum="9" said="A" ent="1" seq="9" icode=" " resname="DC" altcode=" ">
		<clash atom="H2''" dist="2.41" clashmag="0.56" cid="23"/>
		<clash atom="O5'" dist="2.18" clashmag="0.44" cid="26"/>
		<angle-outlier atom0="P" atom1="O3'" atom2="C3'" obs="130.001" z="6.53" mean="120.200" stdev="1.500" link="yes"/>
	</ModelledSubgroup>
	<ModelledSubgroup num-H-reduce="11" model="1" chain="A" resnum="10" said="A" ent="1" seq="10" icode=" " resname="DG" altcode=" ">
		<clash atom="C8" dist="2.41" clashmag="0.56" cid="23"/>
		<clash atom="H8" dist="1.93" clashmag="0.51" cid="24"/>
		<clash atom="H1'" dist="2.47" clashmag="0.50" cid="25"/>
		<clash atom="O3'" dist="2.71" clashmag="0.44" cid="27"/>
		<clash atom="H4'" dist="2.00" clashmag="0.44" cid="28"/>
		<clash atom="H2''" dist="2.56" clashmag="0.41" cid="29"/>
	</ModelledSubgroup>
	<ModelledSubgroup num-H-reduce="11" model="1" chain="A" resnum="11" said="A" ent="1" seq="11" icode=" " resname="DC" altcode=" ">
		<clash atom="C5" dist="2.47" clashmag="0.50" cid="25"/>
		<clash atom="C5" dist="2.56" clashmag="0.41" cid="29"/>
		<clash atom="C6" dist="2.71" clashmag="0.44" cid="27"/>
		<clash atom="H5'" dist="2.00" clashmag="0.44" cid="28"/>
		<angle-outlier atom0="O5'" atom1="P" atom2="OP2" obs="123.141" z="5.05" mean="108.000" stdev="3.000"/>
	</ModelledSubgroup>
	<ModelledSubgroup num-H-reduce="12" model="1" chain="A" resnum="12" said="A" ent="1" seq="12" icode=" " resname="DG" altcode=" ">
		<symm-clash atom="C5'" dist="1.98" clashmag="0.22" symop="1_555" scid="1"/>
		<angle-outlier atom0="C4'" atom1="C3'" atom2="O3'" obs="117.546" z="5.03" mean="110.000" stdev="1.500"/>
	</ModelledSubgroup>
	<ModelledSubgroup mogul-ignore="yes" model="1" chain="A" resnum="26" said="C" ent="2" seq="." icode=" " resname="MG" altcode=" "/>
	<ModelledSubgroup model="1" chain="A" resnum="31" said="E" ent="4" seq="." icode=" " resname="HOH" altcode=" ">
		<symm-clash atom="O" dist="1.87" clashmag="0.33" symop="1_555" scid="0"/>
		<clash atom="O" dist="2.17" clashmag="0.45" cid="30"/>
	</ModelledSubgroup>
	<ModelledSubgroup model="1" chain="A" resnum="35" said="E" ent="4" seq="." icode=" " resname="HOH" altcode=" ">
		<clash atom="O" dist="1.93" clashmag="0.51" cid="24"/>
	</ModelledSubgroup>
	<ModelledSubgroup model="1" chain="A" resnum="44" said="E" ent="4" seq="." icode=" " resname="HOH" altcode=" ">
		<clash atom="O" dist="1.99" clashmag="0.61" cid="22"/>
	</ModelledSubgroup>
	<ModelledSubgroup model="1" chain="A" resnum="87" said="E" ent="4" seq="." icode=" " resname="HOH" altcode=" ">
		<clash atom="O" dist="1.74" clashmag="0.88" cid="0"/>
		<clash atom="O" dist="2.11" clashmag="0.48" cid="10"/>
	</ModelledSubgroup>
	<ModelledSubgroup num-H-reduce="12" model="1" chain="B" resnum="13" said="B" ent="1" seq="1" icode=" " resname="DC" altcode=" ">
		<clash atom="H2''" dist="2.13" clashmag="0.83" cid="17"/>
		<clash atom="H2''" dist="2.19" clashmag="0.57" cid="18"/>
	</ModelledSubgroup>
	<ModelledSubgroup num-H-reduce="11" model="1" chain="B" resnum="14" said="B" ent="1" seq="2" icode=" " resname="DG" altcode=" ">
		<clash atom="C8" dist="2.13" clashmag="0.83" cid="17"/>
		<clash atom="N7" dist="2.19" clashmag="0.57" cid="18"/>
	</ModelledSubgroup>
	<ModelledSubgroup num-H-reduce="11" model="1" chain="B" resnum="15" said="B" ent="1" seq="3" icode=" " resname="DC" altcode=" ">
		<angle-outlier atom0="P" atom1="O3'" atom2="C3'" obs="132.681" z="8.32" mean="120.200" stdev="1.500" link="yes"/>
	</ModelledSubgroup>
	<ModelledSubgroup num-H-reduce="11" model="1" chain="B" resnum="16" said="B" ent="1" seq="4" icode=" " resname="DG" altcode=" ">
		<symm-clash atom="N3" dist="2.09" clashmag="0.11" symop="1_555" scid="2"/>
		<clash atom="H2''" dist="2.39" clashmag="0.57" cid="5"/>
		<angle-outlier atom0="P" atom1="O3'" atom2="C3'" obs="134.872" z="9.78" mean="120.200" stdev="1.500" link="yes"/>
	</ModelledSubgroup>
	<ModelledSubgroup num-H-reduce="11" model="1" chain="B" resnum="17" said="B" ent="1" seq="5" icode=" " resname="DA" altcode=" ">
		<clash atom="C8" dist="2.39" clashmag="0.57" cid="5"/>
		<clash atom="O5'" dist="2.16" clashmag="0.45" cid="12"/>
		<clash atom="O5'" dist="2.67" clashmag="0.42" cid="14"/>
		<clash atom="H2'" dist="2.16" clashmag="0.45" cid="12"/>
		<clash atom="H2''" dist="2.16" clashmag="0.45" cid="13"/>
		<clash atom="C2'" dist="2.67" clashmag="0.42" cid="14"/>
		<angle-outlier atom0="O5'" atom1="C5'" atom2="C4'" obs="101.859" z="-5.96" mean="110.800" stdev="1.500"/>
	</ModelledSubgroup>
	<ModelledSubgroup num-H-reduce="11" model="1" chain="B" resnum="18" said="B" ent="1" seq="6" icode=" " resname="DA" altcode=" ">
		<clash atom="N3" dist="1.94" clashmag="0.82" cid="1"/>
		<clash atom="H4'" dist="1.71" clashmag="0.70" cid="2"/>
		<clash atom="H4'" dist="2.42" clashmag="0.47" cid="11"/>
		<clash atom="H1'" dist="1.82" clashmag="0.61" cid="3"/>
		<clash atom="C2" dist="2.38" clashmag="0.58" cid="4"/>
		<clash atom="C2" dist="2.44" clashmag="0.52" cid="8"/>
		<clash atom="H2" dist="1.73" clashmag="0.54" cid="6"/>
		<clash atom="OP2" dist="2.16" clashmag="0.45" cid="13"/>
		<clash atom="C1'" dist="2.47" clashmag="0.41" cid="16"/>
		<angle-outlier atom0="P" atom1="O3'" atom2="C3'" obs="133.236" z="8.69" mean="120.200" stdev="1.500" link="yes"/>
	</ModelledSubgroup>
	<ModelledSubgroup num-H-reduce="12" model="1" chain="B" resnum="19" said="B" ent="1" seq="7" icode=" " resname="DT" altcode=" ">
		<clash atom="H2'" dist="1.89" clashmag="0.73" cid="19"/>
		<angle-outlier atom0="P" atom1="O5'" atom2="C5'" obs="112.382" z="-5.08" mean="120.000" stdev="1.500"/>
	</ModelledSubgroup>
	<ModelledSubgroup num-H-reduce="12" model="1" chain="B" resnum="20" said="B" ent="1" seq="8" icode=" " resname="DT" altcode=" ">
		<angle-outlier atom0="C2'" atom1="C3'" atom2="O3'" obs="119.077" z="5.05" mean="111.500" stdev="1.500"/>
	</ModelledSubgroup>
	<ModelledSubgroup num-H-reduce="11" model="1" chain="B" resnum="21" said="B" ent="1" seq="9" icode=" " resname="DC" altcode=" ">
		<angle-outlier atom0="P" atom1="O3'" atom2="C3'" obs="132.954" z="8.50" mean="120.200" stdev="1.500" link="yes"/>
		<angle-outlier atom0="O5'" atom1="C5'" atom2="C4'" obs="102.316" z="-5.66" mean="110.800" stdev="1.500"/>
		<angle-outlier atom0="P" atom1="O5'" atom2="C5'" obs="130.136" z="6.76" mean="120.000" stdev="1.500"/>
	</ModelledSubgroup>
	<ModelledSubgroup num-H-reduce="11" model="1" chain="B" resnum="22" said="B" ent="1" seq="10" icode=" " resname="DG" altcode=" ">
		<angle-outlier atom0="P" atom1="O5'" atom2="C5'" obs="128.450" z="5.63" mean="120.000" stdev="1.500"/>
	</ModelledSubgroup>
	<ModelledSubgroup num-H-reduce="11" model="1" chain="B" resnum="23" said="B" ent="1" seq="11" icode=" " resname="DC" altcode=" ">
		<clash atom="H2''" dist="1.77" clashmag="0.67" cid="20"/>
		<clash atom="H2'" dist="2.31" clashmag="0.65" cid="21"/>
		<angle-outlier atom0="C5'" atom1="C4'" atom2="C3'" obs="124.409" z="6.34" mean="114.900" stdev="1.500"/>
		<angle-outlier atom0="O5'" atom1="C5'" atom2="C4'" obs="119.972" z="6.12" mean="110.800" stdev="1.500"/>
	</ModelledSubgroup>
	<ModelledSubgroup num-H-reduce="12" model="1" chain="B" resnum="24" said="B" ent="1" seq="12" icode=" " resname="DG" altcode=" ">
		<symm-clash atom="O3'" dist="2.09" clashmag="0.11" symop="2_664" scid="2"/>
		<clash atom="H5'" dist="1.77" clashmag="0.67" cid="20"/>
		<clash atom="C8" dist="2.31" clashmag="0.65" cid="21"/>
		<angle-outlier atom0="C5'" atom1="C4'" atom2="C3'" obs="123.545" z="5.76" mean="114.900" stdev="1.500"/>
		<angle-outlier atom0="O5'" atom1="C5'" atom2="C4'" obs="118.490" z="5.13" mean="110.800" stdev="1.500"/>
	</ModelledSubgroup>
	<ModelledSubgroup num-H-reduce="22" ligand_clashes_outlier="yes" ligand_num_symm_clashes="0" ligand_num_clashes="13" mogul_bonds_rmsz="3.89" mogul_angles_rmsz="2.66" mogul_rmsz_numangles="54" mogul_rmsz_numbonds="37" model="1" chain="B" resnum="25" said="D" ent="3" seq="." icode=" " resname="HT" altcode=" ">
		<clash atom="H18" dist="1.74" clashmag="0.88" cid="0"/>
		<clash atom="H18" dist="1.58" clashmag="0.42" cid="15"/>
		<clash atom="H242" dist="1.94" clashmag="0.82" cid="1"/>
		<clash atom="H242" dist="2.44" clashmag="0.52" cid="8"/>
		<clash atom="H252" dist="1.71" clashmag="0.70" cid="2"/>
		<clash atom="H231" dist="1.82" clashmag="0.61" cid="3"/>
		<clash atom="H231" dist="2.47" clashmag="0.41" cid="16"/>
		<clash atom="H20" dist="2.38" clashmag="0.58" cid="4"/>
		<clash atom="H20" dist="1.73" clashmag="0.54" cid="6"/>
		<clash atom="H13" dist="1.73" clashmag="0.52" cid="7"/>
		<clash atom="H13" dist="2.46" clashmag="0.51" cid="9"/>
		<clash atom="H211" dist="2.11" clashmag="0.48" cid="10"/>
		<clash atom="H211" dist="1.58" clashmag="0.42" cid="15"/>
		<clash atom="C25" dist="2.42" clashmag="0.47" cid="11"/>
		<mog-angle-outlier atoms="C8,C9,N2" numobs="1751" mean="109.42" stdev="1.37" mindiff="0.01" Zscore="-2.20" obsval="106.41"/>
		<mog-angle-outlier atoms="C10,C9,C8" numobs="1600" mean="120.26" stdev="1.10" mindiff="0.01" Zscore="2.08" obsval="122.55"/>
		<mog-angle-outlier atoms="C9,N2,C7" numobs="774" mean="105.17" stdev="1.17" mindiff="0.01" Zscore="2.88" obsval="108.53"/>
		<mog-angle-outlier atoms="C11,C12,C13" numobs="11345" mean="119.25" stdev="1.16" mindiff="0.00" Zscore="2.06" obsval="121.63"/>
		<mog-angle-outlier atoms="C12,C14,N3" numobs="977" mean="123.23" stdev="1.63" mindiff="0.05" Zscore="2.11" obsval="126.68"/>
		<mog-angle-outlier atoms="C12,C14,N4" numobs="978" mean="124.20" stdev="1.74" mindiff="0.01" Zscore="-2.78" obsval="119.36"/>
		<mog-angle-outlier atoms="C15,N3,C14" numobs="758" mean="107.06" stdev="1.01" mindiff="0.63" Zscore="3.97" obsval="111.05"/>
		<mog-angle-outlier atoms="C20,C15,N3" numobs="1027" mean="130.65" stdev="2.05" mindiff="7.45" Zscore="6.75" obsval="144.48"/>
		<mog-angle-outlier atoms="C20,C15,C16" numobs="445" mean="122.17" stdev="1.48" mindiff="4.52" Zscore="-6.88" obsval="111.96"/>
		<mog-angle-outlier atoms="C17,C16,C15" numobs="1600" mean="120.26" stdev="1.10" mindiff="0.48" Zscore="8.23" obsval="129.34"/>
		<mog-angle-outlier atoms="C18,C17,C16" numobs="2043" mean="119.97" stdev="1.66" mindiff="0.52" Zscore="-4.34" obsval="112.74"/>
		<mog-angle-outlier atoms="C18,C19,C20" numobs="7668" mean="119.12" stdev="1.99" mindiff="0.02" Zscore="-2.33" obsval="114.50"/>
		<mog-angle-outlier atoms="C18,C19,N5" numobs="10049" mean="121.39" stdev="1.39" mindiff="0.01" Zscore="-3.14" obsval="117.03"/>
		<mog-angle-outlier atoms="C20,C19,N5" numobs="2899" mean="121.33" stdev="1.08" mindiff="1.21" Zscore="6.63" obsval="128.47"/>
		<mog-angle-outlier atoms="C19,C20,C15" numobs="55" mean="119.85" stdev="2.42" mindiff="6.60" Zscore="4.29" obsval="130.22"/>
		<mog-angle-outlier atoms="C24,C23,N6" numobs="1223" mean="110.86" stdev="1.61" mindiff="0.32" Zscore="-4.78" obsval="103.18"/>
		<mog-angle-outlier atoms="C23,C24,N5" numobs="3155" mean="110.78" stdev="2.10" mindiff="0.01" Zscore="-2.33" obsval="105.89"/>
		<mog-bond-outlier atoms="C12,C14" numobs="2710" mean="1.47" stdev="0.02" mindiff="0.00" Zscore="-2.08" obsval="1.43"/>
		<mog-bond-outlier atoms="C14,N3" numobs="1653" mean="1.36" stdev="0.02" mindiff="0.05" Zscore="-9.57" obsval="1.17"/>
		<mog-bond-outlier atoms="C15,C16" numobs="2060" mean="1.40" stdev="0.01" mindiff="0.00" Zscore="-2.49" obsval="1.36"/>
		<mog-bond-outlier atoms="C20,C15" numobs="6649" mean="1.39" stdev="0.02" mindiff="0.02" Zscore="-9.94" obsval="1.23"/>
		<mog-bond-outlier atoms="C19,N5" numobs="6589" mean="1.38" stdev="0.03" mindiff="0.00" Zscore="3.79" obsval="1.49"/>
		<mog-bond-outlier atoms="C21,N5" numobs="9559" mean="1.46" stdev="0.02" mindiff="0.08" Zscore="-17.67" obsval="1.16"/>
	</ModelledSubgroup>
	<ModelledSubgroup model="1" chain="B" resnum="29" said="F" ent="4" seq="." icode=" " resname="HOH" altcode=" ">
		<clash atom="O" dist="1.89" clashmag="0.73" cid="19"/>
	</ModelledSubgroup>
	<ModelledSubgroup model="1" chain="B" resnum="56" said="F" ent="4" seq="." icode=" " resname="HOH" altcode=" ">
		<symm-clash atom="O" dist="1.98" clashmag="0.22" symop="2_664" scid="1"/>
	</ModelledSubgroup>
	<ModelledSubgroup model="1" chain="B" resnum="85" said="F" ent="4" seq="." icode=" " resname="HOH" altcode=" ">
		<symm-clash atom="O" dist="1.87" clashmag="0.33" symop="1_655" scid="0"/>
	</ModelledSubgroup>
	<ModelledEntityInstance bonds_rmsz="1.27" num_bonds_rmsz="272" angles_rmsz="2.25" num_angles_rmsz="418" said="A" model="1" chain="A" ent="1"/>
	<ModelledEntityInstance bonds_rmsz="1.21" num_bonds_rmsz="272" angles_rmsz="2.16" num_angles_rmsz="418" said="B" model="1" chain="B" ent="1"/>
	<programs>
		<program name="validation-pipeline" version="2.49" properties="PDB-resolution-low,attemptedValidationSteps,PDB-revision-number,protein-DNA-RNA-entities,PDB-resolution,pdbid,extended_pdbid,percentilebins,PDB-Rfree,PDB-deposition-date,XMLcreationDate,PDB-R,PDB-revision-date"/>
		<program name="validation-pack" version="unknown" properties="symm-clash"/>
		<program name="molprobity" version="4-5-2 with Phenix2.0" properties="bonds_rmsz,angles_rmsz,bond-outlier,clash,clashscore,ligand_num_clashes,ligand_num_symm_clashes,angle-outlier,num-H-reduce,num_bonds_rmsz,ligand_clashes_outlier,num_angles_rmsz,RestypesNotcheckedForBondAngleGeometry"/>
		<program name="mogul" version="2022.3.0, CSD as543be (2022)" properties="mogul-ring-outlier,mogul-bond-outlier,mogul-angle-outlier,mogul_rmsz_numangles,mogul-torsion-outlier,mogul-ignore,mogul_angles_rmsz,mogul_bonds_rmsz,mogul_rmsz_numbonds"/>
		<program name="buster-report" version="wwPDB partial adaption of 1.1.7 (2018)" properties="ligands-for-buster-report"/>
		<program name="percentiles" version="20250101.v01 (using entries in the PDB archive January 1st 2025)" properties="low-resol-relative-percentile-clashscore,relative-percentile-clashscore,numPDBids-relative-percentile-clashscore,high-resol-relative-percentile-clashscore,numPDBids-absolute-percentile-clashscore,absolute-percentile-clashscore"/>
	</programs>
</wwPDB-validation-information>
