<?xml version="1.0" ?>
<wwPDB-validation-information xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:noNamespaceSchemaLocation="http://wwpdb.org/validation/schema/wwpdb_validation_v6.06.xsd">
	<Entry percentilebins="all,nmr" attemptedValidationSteps="mogul,buster-report,molprobity,validation-pack,coreclust,chemicalshiftanalysis,percentiles,writexml" PDB-deposition-date="2006-12-11" PDB-revision-date="2024-05-29" PDB-revision-number="4" protein-DNA-RNA-entities="1" PDB-resolution="NotAvailable" PDB-resolution-low="NotAvailable" PDB-R="NotAvailable" PDB-Rfree="NotAvailable" pdbid="2E4I" extended_pdbid="2E4I" no-ligands-for-buster-report="yes" num-H-reduce="245" angles_rmsz="0.55" num_angles_rmsz="617" num_bonds_rmsz="399" clashscore-full-length="55.94" bonds_rmsz="0.56" RestypesNotcheckedForBondAngleGeometry="BGM" rci_version="v_1n_11_5_13_A (Berjanski et al., 2005)" shiftchecker_version="v1.2" panav_version="Wang et al. (2010)" cyrange_error="Not enough models (&lt;3)" nmr_models_consistency_flag="True" clashscore="55.94" absolute-percentile-clashscore="1.4" numPDBids-absolute-percentile-clashscore="229148" relative-percentile-clashscore="10.6" numPDBids-relative-percentile-clashscore="14424" XMLcreationDate="Mar  5, 2026 -- 12:11 PM UTC"/>
	<ModelledSubgroup num-H-reduce="12" validate="True" model="1" chain="A" resnum="1" said="A" ent="1" seq="1" icode=" " resname="DA" altcode=" "/>
	<ModelledSubgroup mogul_bonds_rmsz="0.72" mogul_rmsz_numbonds="22" mogul_angles_rmsz="0.58" mogul_rmsz_numangles="28" num-H-reduce="10" validate="True" model="1" chain="A" resnum="2" said="A" ent="1" seq="2" icode=" " resname="BGM" altcode=" ">
		<mog-bond-outlier atoms="BR,C8" numobs="102" mean="1.86" stdev="0.02" mindiff="0.01" Zscore="3.07" obsval="1.91"/>
		<mog-angle-outlier atoms="N9,C8,N7" numobs="25" mean="115.04" stdev="0.78" mindiff="0.25" Zscore="-2.34" obsval="113.22"/>
		<mog-torsion-outlier atoms="C3',C4',C5',O5'" numobs="522" mean="92.71" stdev="30.77" mindiff="0.04" local_density="2.11" obsval="-158.43"/>
		<clash atom="N3" dist="2.04" clashmag="0.67" cid="0"/>
		<clash atom="N3" dist="2.80" clashmag="0.42" cid="18"/>
		<clash atom="H2'" dist="2.04" clashmag="0.67" cid="0"/>
		<clash atom="BR" dist="3.20" clashmag="0.45" cid="13"/>
		<clash atom="BR" dist="2.93" clashmag="0.42" cid="16"/>
		<clash atom="C2'" dist="2.80" clashmag="0.42" cid="18"/>
	</ModelledSubgroup>
	<ModelledSubgroup num-H-reduce="11" validate="True" model="1" chain="A" resnum="3" said="A" ent="1" seq="3" icode=" " resname="DG" altcode=" ">
		<clash atom="N2" dist="2.49" clashmag="0.60" cid="1"/>
		<clash atom="N2" dist="2.70" clashmag="0.58" cid="3"/>
	</ModelledSubgroup>
	<ModelledSubgroup num-H-reduce="11" validate="True" model="1" chain="A" resnum="4" said="A" ent="1" seq="4" icode=" " resname="DG" altcode=" ">
		<clash atom="H4'" dist="2.09" clashmag="0.47" cid="9"/>
		<clash atom="O4'" dist="2.13" clashmag="0.44" cid="15"/>
	</ModelledSubgroup>
	<ModelledSubgroup num-H-reduce="12" validate="True" model="1" chain="A" resnum="5" said="A" ent="1" seq="5" icode=" " resname="DT" altcode=" ">
		<clash atom="H2''" dist="2.07" clashmag="0.50" cid="7"/>
		<clash atom="O5'" dist="2.09" clashmag="0.47" cid="9"/>
		<clash atom="H71" dist="2.13" clashmag="0.44" cid="15"/>
		<clash atom="O4" dist="2.93" clashmag="0.42" cid="16"/>
	</ModelledSubgroup>
	<ModelledSubgroup num-H-reduce="12" validate="True" model="1" chain="A" resnum="6" said="A" ent="1" seq="6" icode=" " resname="DT" altcode=" ">
		<clash atom="O5'" dist="2.07" clashmag="0.50" cid="7"/>
	</ModelledSubgroup>
	<ModelledSubgroup num-H-reduce="11" validate="True" model="1" chain="A" resnum="7" said="A" ent="1" seq="7" icode=" " resname="DA" altcode=" ">
		<clash atom="N3" dist="2.49" clashmag="0.60" cid="1"/>
		<clash atom="C2" dist="2.70" clashmag="0.58" cid="3"/>
		<clash atom="C4'" dist="2.11" clashmag="0.57" cid="4"/>
		<clash atom="C4'" dist="2.78" clashmag="0.46" cid="11"/>
		<clash atom="C1'" dist="2.22" clashmag="0.48" cid="8"/>
		<clash atom="C5'" dist="3.20" clashmag="0.45" cid="13"/>
		<clash atom="O4'" dist="2.50" clashmag="0.45" cid="14"/>
	</ModelledSubgroup>
	<ModelledSubgroup mogul_bonds_rmsz="0.77" mogul_rmsz_numbonds="22" mogul_angles_rmsz="0.69" mogul_rmsz_numangles="28" ligand_clashes_outlier="yes" num-H-reduce="10" ligand_num_clashes="12" ligand_num_symm_clashes="0" validate="True" model="1" chain="A" resnum="8" said="A" ent="1" seq="8" icode=" " resname="BGM" altcode=" ">
		<mog-bond-outlier atoms="BR,C8" numobs="102" mean="1.86" stdev="0.02" mindiff="0.01" Zscore="3.24" obsval="1.92"/>
		<mog-angle-outlier atoms="N9,C8,N7" numobs="25" mean="115.04" stdev="0.78" mindiff="0.15" Zscore="-2.48" obsval="113.12"/>
		<mog-torsion-outlier atoms="O4',C4',C5',O5'" numobs="522" mean="26.08" stdev="16.89" mindiff="0.13" local_density="3.07" obsval="-87.31"/>
		<mog-torsion-outlier atoms="C3',C4',C5',O5'" numobs="522" mean="37.86" stdev="39.60" mindiff="0.35" local_density="3.83" obsval="31.61"/>
		<bond-outlier atom0="O3'" atom1="P" obs="1.610" z="5.16" mean="1.558" stdev="0.010" link="yes"/>
		<clash atom="H2''" dist="1.96" clashmag="0.59" cid="2"/>
		<clash atom="H21" dist="2.11" clashmag="0.57" cid="4"/>
		<clash atom="H21" dist="2.22" clashmag="0.48" cid="8"/>
		<clash atom="C2'" dist="2.54" clashmag="0.56" cid="5"/>
		<clash atom="H1'" dist="2.04" clashmag="0.52" cid="6"/>
		<clash atom="O6" dist="2.68" clashmag="0.47" cid="10"/>
		<clash atom="N2" dist="2.78" clashmag="0.46" cid="11"/>
		<clash atom="N2" dist="2.50" clashmag="0.45" cid="14"/>
		<clash atom="N3" dist="2.26" clashmag="0.46" cid="12"/>
		<clash atom="H2'" dist="2.26" clashmag="0.46" cid="12"/>
		<clash atom="C5" dist="2.82" clashmag="0.42" cid="17"/>
		<clash atom="C1'" dist="2.68" clashmag="0.41" cid="19"/>
		<clash atom="C6" dist="2.84" clashmag="0.41" cid="20"/>
	</ModelledSubgroup>
	<ModelledSubgroup num-H-reduce="11" validate="True" model="1" chain="A" resnum="9" said="A" ent="1" seq="9" icode=" " resname="DG" altcode=" ">
		<clash atom="O5'" dist="1.96" clashmag="0.59" cid="2"/>
		<clash atom="O5'" dist="2.54" clashmag="0.56" cid="5"/>
		<clash atom="O5'" dist="2.04" clashmag="0.52" cid="6"/>
		<clash atom="O5'" dist="2.68" clashmag="0.41" cid="19"/>
		<clash atom="C6" dist="2.68" clashmag="0.47" cid="10"/>
		<clash atom="N7" dist="2.82" clashmag="0.42" cid="17"/>
		<clash atom="N7" dist="2.84" clashmag="0.41" cid="20"/>
	</ModelledSubgroup>
	<ModelledSubgroup num-H-reduce="11" validate="True" model="1" chain="A" resnum="10" said="A" ent="1" seq="10" icode=" " resname="DG" altcode=" "/>
	<ModelledSubgroup num-H-reduce="12" validate="True" model="1" chain="A" resnum="11" said="A" ent="1" seq="11" icode=" " resname="DT" altcode=" ">
		<clash atom="O3'" dist="2.18" clashmag="0.61" cid="22"/>
		<clash atom="O3'" dist="2.66" clashmag="0.43" cid="32"/>
	</ModelledSubgroup>
	<ModelledSubgroup num-H-reduce="12" validate="True" model="1" chain="A" resnum="12" said="A" ent="1" seq="12" icode=" " resname="DT" altcode=" ">
		<clash atom="O4'" dist="2.18" clashmag="0.61" cid="22"/>
		<clash atom="N3" dist="2.50" clashmag="0.59" cid="23"/>
		<clash atom="C4" dist="2.73" clashmag="0.57" cid="25"/>
		<clash atom="C4" dist="2.84" clashmag="0.46" cid="28"/>
		<clash atom="C2" dist="2.84" clashmag="0.46" cid="27"/>
		<clash atom="C2" dist="3.06" clashmag="0.42" cid="33"/>
		<clash atom="C7" dist="2.80" clashmag="0.45" cid="30"/>
		<clash atom="H72" dist="2.49" clashmag="0.43" cid="31"/>
		<clash atom="H72" dist="2.30" clashmag="0.41" cid="35"/>
		<clash atom="C4'" dist="2.66" clashmag="0.43" cid="32"/>
		<clash atom="O4" dist="2.51" clashmag="0.41" cid="34"/>
	</ModelledSubgroup>
	<ModelledSubgroup num-H-reduce="11" validate="True" model="1" chain="A" resnum="13" said="A" ent="1" seq="13" icode=" " resname="DA" altcode=" ">
		<clash atom="N7" dist="2.50" clashmag="0.59" cid="23"/>
		<clash atom="N7" dist="2.73" clashmag="0.57" cid="25"/>
		<clash atom="N7" dist="2.84" clashmag="0.46" cid="27"/>
		<clash atom="N6" dist="2.84" clashmag="0.46" cid="28"/>
		<clash atom="N6" dist="2.80" clashmag="0.45" cid="30"/>
		<clash atom="N6" dist="2.51" clashmag="0.41" cid="34"/>
		<clash atom="N6" dist="2.30" clashmag="0.41" cid="35"/>
		<clash atom="C8" dist="2.99" clashmag="0.46" cid="29"/>
		<clash atom="C8" dist="3.06" clashmag="0.42" cid="33"/>
		<clash atom="C6" dist="2.49" clashmag="0.43" cid="31"/>
	</ModelledSubgroup>
	<ModelledSubgroup mogul_bonds_rmsz="0.76" mogul_rmsz_numbonds="22" mogul_angles_rmsz="0.65" mogul_rmsz_numangles="28" num-H-reduce="10" validate="True" model="1" chain="A" resnum="14" said="A" ent="1" seq="14" icode=" " resname="BGM" altcode=" ">
		<mog-bond-outlier atoms="BR,C8" numobs="102" mean="1.86" stdev="0.02" mindiff="0.01" Zscore="3.26" obsval="1.92"/>
		<mog-angle-outlier atoms="N9,C8,N7" numobs="25" mean="115.04" stdev="0.78" mindiff="0.19" Zscore="-2.42" obsval="113.16"/>
		<clash atom="H2''" dist="1.99" clashmag="0.57" cid="24"/>
		<clash atom="N3" dist="2.18" clashmag="0.54" cid="26"/>
		<clash atom="H2'" dist="2.18" clashmag="0.54" cid="26"/>
		<clash atom="C6" dist="2.99" clashmag="0.46" cid="29"/>
	</ModelledSubgroup>
	<ModelledSubgroup mogul_bonds_rmsz="0.75" mogul_rmsz_numbonds="22" mogul_angles_rmsz="0.64" mogul_rmsz_numangles="28" num-H-reduce="10" validate="True" model="1" chain="A" resnum="15" said="A" ent="1" seq="15" icode=" " resname="BGM" altcode=" ">
		<mog-bond-outlier atoms="BR,C8" numobs="102" mean="1.86" stdev="0.02" mindiff="0.01" Zscore="3.19" obsval="1.91"/>
		<mog-angle-outlier atoms="N9,C8,N7" numobs="25" mean="115.04" stdev="0.78" mindiff="0.21" Zscore="-2.40" obsval="113.18"/>
		<mog-torsion-outlier atoms="O4',C1',N9,C8" numobs="44" mean="42.96" stdev="20.22" mindiff="8.89" local_density="4.55" obsval="-141.37"/>
		<mog-torsion-outlier atoms="O4',C1',N9,C4" numobs="44" mean="59.45" stdev="20.22" mindiff="14.59" local_density="0.00" obsval="38.96"/>
		<mog-torsion-outlier atoms="C2',C1',N9,C8" numobs="46" mean="41.55" stdev="18.41" mindiff="6.62" local_density="4.35" obsval="101.43"/>
		<mog-torsion-outlier atoms="C2',C1',N9,C4" numobs="46" mean="51.63" stdev="17.45" mindiff="15.01" local_density="0.00" obsval="-78.24"/>
		<clash atom="H2''" dist="1.91" clashmag="0.66" cid="21"/>
		<clash atom="O5'" dist="1.99" clashmag="0.57" cid="24"/>
		<clash atom="BR" dist="2.95" clashmag="0.40" cid="36"/>
	</ModelledSubgroup>
	<ModelledSubgroup num-H-reduce="11" validate="True" model="1" chain="A" resnum="16" said="A" ent="1" seq="16" icode=" " resname="DG" altcode=" ">
		<clash atom="O5'" dist="1.91" clashmag="0.66" cid="21"/>
		<clash atom="O4'" dist="2.95" clashmag="0.40" cid="36"/>
	</ModelledSubgroup>
	<ModelledSubgroup num-H-reduce="12" validate="True" model="1" chain="A" resnum="17" said="A" ent="1" seq="17" icode=" " resname="DT" altcode=" "/>
	<ModelledSubgroup num-H-reduce="12" validate="True" model="1" chain="A" resnum="18" said="A" ent="1" seq="18" icode=" " resname="DT" altcode=" "/>
	<ModelledSubgroup num-H-reduce="11" validate="True" model="1" chain="A" resnum="19" said="A" ent="1" seq="19" icode=" " resname="DA" altcode=" "/>
	<ModelledSubgroup mogul_bonds_rmsz="0.75" mogul_rmsz_numbonds="22" mogul_angles_rmsz="0.70" mogul_rmsz_numangles="28" num-H-reduce="10" validate="True" model="1" chain="A" resnum="20" said="A" ent="1" seq="20" icode=" " resname="BGM" altcode=" ">
		<mog-bond-outlier atoms="BR,C8" numobs="102" mean="1.86" stdev="0.02" mindiff="0.01" Zscore="3.26" obsval="1.92"/>
		<mog-angle-outlier atoms="N9,C8,N7" numobs="25" mean="115.04" stdev="0.78" mindiff="0.16" Zscore="-2.46" obsval="113.13"/>
		<mog-torsion-outlier atoms="O4',C1',N9,C4" numobs="44" mean="29.42" stdev="15.96" mindiff="1.49" local_density="4.55" obsval="71.73"/>
		<clash atom="C4'" dist="2.65" clashmag="0.44" cid="37"/>
		<clash atom="O4'" dist="2.37" clashmag="0.43" cid="38"/>
		<clash atom="H5''" dist="2.30" clashmag="0.41" cid="39"/>
		<clash atom="N3" dist="2.30" clashmag="0.41" cid="39"/>
	</ModelledSubgroup>
	<ModelledSubgroup num-H-reduce="11" validate="True" model="1" chain="A" resnum="21" said="A" ent="1" seq="21" icode=" " resname="DG" altcode=" ">
		<clash atom="OP1" dist="2.65" clashmag="0.44" cid="37"/>
		<clash atom="OP1" dist="2.37" clashmag="0.43" cid="38"/>
	</ModelledSubgroup>
	<ModelledSubgroup num-H-reduce="12" validate="True" model="1" chain="A" resnum="22" said="A" ent="1" seq="22" icode=" " resname="DG" altcode=" "/>
	<ModelledEntityInstance bonds_rmsz="0.56" num_bonds_rmsz="399" angles_rmsz="0.55" num_angles_rmsz="617" said="A" model="1" chain="A" ent="1"/>
	<programs>
		<program name="validation-pipeline" version="2.49" properties="pdbid,PDB-R,percentilebins,XMLcreationDate,extended_pdbid,attemptedValidationSteps,PDB-revision-date,PDB-revision-number,protein-DNA-RNA-entities,PDB-Rfree,PDB-resolution-low,PDB-deposition-date,PDB-resolution"/>
		<program name="mogul" version="2022.3.0, CSD as543be (2022)" properties="mogul-bond-outlier,mogul-torsion-outlier,mogul-angle-outlier,mogul_angles_rmsz,mogul_rmsz_numangles,mogul_rmsz_numbonds,mogul-ring-outlier,mogul_bonds_rmsz"/>
		<program name="buster-report" version="unknown" properties="no-ligands-for-buster-report"/>
		<program name="molprobity" version="4-5-2 with Phenix2.0" properties="ligand_clashes_outlier,num-H-reduce,num_angles_rmsz,clashscore-full-length,bonds_rmsz,ligand_num_clashes,num_bonds_rmsz,ligand_num_symm_clashes,angle-outlier,clash,angles_rmsz,RestypesNotcheckedForBondAngleGeometry,bond-outlier"/>
		<program name="coreclust" version="2.49" properties="validate"/>
		<program name="chemicalshiftanalysis" version="v1.2" properties="rci_version,shiftchecker_version,panav_version"/>
		<program name="coreclust" version="unknown" properties="cyrange_error,nmr_models_consistency_flag"/>
		<program name="nmrwriter" version="2.49" properties="clashscore"/>
		<program name="percentiles" version="20250101.v01 (using entries in the PDB archive January 1st 2025)" properties="numPDBids-relative-percentile-clashscore,numPDBids-absolute-percentile-clashscore,absolute-percentile-clashscore,relative-percentile-clashscore"/>
	</programs>
</wwPDB-validation-information>
