<?xml version="1.0" ?>
<wwPDB-validation-information xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:noNamespaceSchemaLocation="http://wwpdb.org/validation/schema/wwpdb_validation_v6.06.xsd">
	<Entry percentilebins="all,2.04,xray" attemptedValidationSteps="molprobity,validation-pack,xtriage,eds,mogul,buster-report,percentiles,writexml" PDB-deposition-date="2014-10-27" PDB-revision-date="2023-09-20" PDB-revision-number="3" protein-DNA-RNA-entities="1" PDB-resolution="2.04" PDB-resolution-low="34.99" PDB-R="0.2260" PDB-Rfree="0.2599" pdbid="4RO4" extended_pdbid="4RO4" num-H-reduce="135" clashscore="5.13" RestypesNotcheckedForBondAngleGeometry="MG" bonds_rmsz="0.40" num_bonds_rmsz="286" angles_rmsz="0.76" num_angles_rmsz="442" TwinL2="0.349" TwinFraction="h,-h-k,-l:0.127" centric_outliers="1" WilsonBestimate="67.649" numMillerIndices="3229" WilsonBaniso="[76.079,76.079,60.075,-0.000,0.000,0.000]" TransNCS="The largest off-origin peak in the Patterson function is 8.71% of the height of the origin peak. No significant pseudotranslation is detected." TwinL="0.512" acentric_outliers="5" xtriage_input_columns="F_meas_au,F_meas_sigma_au" DataAnisotropy="0.226" IoverSigma="1.36(2.05A)" DCC_R="0.2290" EDS_resolution="2.04" percent-free-reflections="8.46" B_factor_type="FULL" percent-RSRZ-outliers="0.00" DCC_refinement_program="REFMAC" bulk_solvent_k="0.418" EDS_R="0.2360" bulk_solvent_b="94.555" Fo_Fc_correlation="0.967" DataCompleteness="98.63" no-ligands-for-buster-report="yes" EDS_resolution_low="34.99" DCC_Rfree="0.2663" CCP4version="9.0.010 (Gargrove)" num-free-reflections="277" density-fitnessVersion="1.0.12" absolute-percentile-clashscore="51.9" numPDBids-absolute-percentile-clashscore="190562" relative-percentile-clashscore="45.4" numPDBids-relative-percentile-clashscore="2333" low-resol-relative-percentile-clashscore="2.04" high-resol-relative-percentile-clashscore="2.04" absolute-percentile-percent-RSRZ-outliers="100.0" numPDBids-absolute-percentile-percent-RSRZ-outliers="180081" relative-percentile-percent-RSRZ-outliers="100.0" numPDBids-relative-percentile-percent-RSRZ-outliers="2260" low-resol-relative-percentile-percent-RSRZ-outliers="2.04" high-resol-relative-percentile-percent-RSRZ-outliers="2.04" absolute-percentile-DCC_Rfree="19.5" numPDBids-absolute-percentile-DCC_Rfree="180053" relative-percentile-DCC_Rfree="11.9" numPDBids-relative-percentile-DCC_Rfree="2260" low-resol-relative-percentile-DCC_Rfree="2.04" high-resol-relative-percentile-DCC_Rfree="2.04" XMLcreationDate="Mar 13, 2026 -- 10:47 AM UTC"/>
	<ModelledSubgroup num-H-reduce="12" avgoccu="1.000" owab="76.130" rsrz="0.694" rsr="0.116" OPIA="57.890" EDIAm="0.523" rscc="0.930" NatomsEDS="19" model="1" chain="A" resnum="1" said="A" ent="1" seq="1" icode=" " resname="DG" altcode=" "/>
	<ModelledSubgroup num-H-reduce="11" avgoccu="1.000" owab="64.860" rsrz="0.011" rsr="0.091" OPIA="72.730" EDIAm="0.809" rscc="0.943" NatomsEDS="22" model="1" chain="A" resnum="2" said="A" ent="1" seq="2" icode=" " resname="DG" altcode=" "/>
	<ModelledSubgroup num-H-reduce="11" avgoccu="1.000" owab="60.080" rsrz="0.332" rsr="0.107" OPIA="71.430" EDIAm="0.798" rscc="0.944" NatomsEDS="21" model="1" chain="A" resnum="3" said="A" ent="1" seq="3" icode=" " resname="DA" altcode=" "/>
	<ModelledSubgroup num-H-reduce="11" avgoccu="1.000" owab="76.520" rsrz="-0.135" rsr="0.089" OPIA="47.620" EDIAm="0.777" rscc="0.963" NatomsEDS="21" model="1" chain="A" resnum="4" said="A" ent="1" seq="4" icode=" " resname="DA" altcode=" ">
		<clash atom="H2''" dist="2.53" clashmag="0.44" cid="0"/>
	</ModelledSubgroup>
	<ModelledSubgroup num-H-reduce="11" avgoccu="1.000" owab="85.940" rsrz="0.565" rsr="0.116" OPIA="42.860" EDIAm="0.757" rscc="0.927" NatomsEDS="21" model="1" chain="A" resnum="5" said="A" ent="1" seq="5" icode=" " resname="DA" altcode=" ">
		<clash atom="C8" dist="2.53" clashmag="0.44" cid="0"/>
	</ModelledSubgroup>
	<ModelledSubgroup num-H-reduce="11" avgoccu="1.000" owab="88.740" rsrz="0.332" rsr="0.108" OPIA="47.370" EDIAm="0.633" rscc="0.928" NatomsEDS="19" model="1" chain="A" resnum="6" said="A" ent="1" seq="6" icode=" " resname="DC" altcode=" "/>
	<ModelledSubgroup num-H-reduce="11" avgoccu="1.000" owab="90.020" rsrz="0.038" rsr="0.092" OPIA="45.450" EDIAm="0.485" rscc="0.931" NatomsEDS="22" model="1" chain="A" resnum="7" said="A" ent="1" seq="7" icode=" " resname="DG" altcode=" "/>
	<ModelledSubgroup num-H-reduce="12" avgoccu="1.000" owab="90.770" rsrz="0.085" rsr="0.100" OPIA="50.000" EDIAm="0.640" rscc="0.942" NatomsEDS="20" model="1" chain="A" resnum="8" said="A" ent="1" seq="8" icode=" " resname="DT" altcode=" "/>
	<ModelledSubgroup num-H-reduce="12" avgoccu="1.000" owab="77.710" rsrz="-0.328" rsr="0.083" OPIA="55.000" EDIAm="0.762" rscc="0.949" NatomsEDS="20" model="1" chain="A" resnum="9" said="A" ent="1" seq="9" icode=" " resname="DT" altcode=" "/>
	<ModelledSubgroup num-H-reduce="11" avgoccu="1.000" owab="70.400" rsrz="0.257" rsr="0.100" OPIA="72.730" EDIAm="0.802" rscc="0.937" NatomsEDS="22" model="1" chain="A" resnum="10" said="A" ent="1" seq="10" icode=" " resname="DG" altcode=" ">
		<clash atom="H2''" dist="2.55" clashmag="0.42" cid="1"/>
	</ModelledSubgroup>
	<ModelledSubgroup num-H-reduce="11" avgoccu="1.000" owab="66.420" rsrz="-0.262" rsr="0.081" OPIA="63.640" EDIAm="0.795" rscc="0.958" NatomsEDS="22" model="1" chain="A" resnum="11" said="A" ent="1" seq="11" icode=" " resname="DG" altcode=" ">
		<clash atom="C8" dist="2.55" clashmag="0.42" cid="1"/>
	</ModelledSubgroup>
	<ModelledSubgroup num-H-reduce="11" avgoccu="1.000" owab="63.640" rsrz="0.098" rsr="0.098" OPIA="80.950" EDIAm="0.848" rscc="0.949" NatomsEDS="21" model="1" chain="A" resnum="12" said="A" ent="1" seq="12" icode=" " resname="DA" altcode=" "/>
	<ModelledSubgroup avgoccu="1.000" owab="103.970" rsrz="-0.344" rsr="0.078" OPIA="50.000" EDIAm="0.725" rscc="0.922" NatomsEDS="4" model="1" chain="A" resnum="13" said="A" ent="1" seq="13" icode=" " resname="DG" altcode=" "/>
	<ModelledSubgroup rscc="0.908" rsr="0.238" EDIAm="0.710" OPIA="0.000" owab="91.440" avgoccu="1.000" NatomsEDS="1" mogul-ignore="yes" model="1" chain="A" resnum="101" said="B" ent="2" seq="." icode=" " resname="MG" altcode=" "/>
	<ModelledSubgroup rscc="0.873" rsr="0.138" EDIAm="0.334" OPIA="0.000" owab="75.010" avgoccu="1.000" NatomsEDS="1" model="1" chain="A" resnum="201" said="C" ent="3" seq="." icode=" " resname="HOH" altcode=" "/>
	<ModelledSubgroup rscc="0.894" rsr="0.155" EDIAm="0.666" OPIA="0.000" owab="51.190" avgoccu="1.000" NatomsEDS="1" model="1" chain="A" resnum="202" said="C" ent="3" seq="." icode=" " resname="HOH" altcode=" "/>
	<ModelledSubgroup rscc="0.905" rsr="0.196" EDIAm="0.291" OPIA="0.000" owab="53.040" avgoccu="1.000" NatomsEDS="1" model="1" chain="A" resnum="203" said="C" ent="3" seq="." icode=" " resname="HOH" altcode=" "/>
	<ModelledSubgroup rscc="0.815" rsr="0.287" EDIAm="0.127" OPIA="0.000" owab="59.260" avgoccu="1.000" NatomsEDS="1" model="1" chain="A" resnum="204" said="C" ent="3" seq="." icode=" " resname="HOH" altcode=" "/>
	<ModelledSubgroup rscc="0.919" rsr="0.153" EDIAm="0.237" OPIA="0.000" owab="70.130" avgoccu="1.000" NatomsEDS="1" model="1" chain="A" resnum="205" said="C" ent="3" seq="." icode=" " resname="HOH" altcode=" "/>
	<ModelledSubgroup rscc="0.900" rsr="0.097" EDIAm="0.851" OPIA="100.000" owab="75.530" avgoccu="1.000" NatomsEDS="1" model="1" chain="A" resnum="206" said="C" ent="3" seq="." icode=" " resname="HOH" altcode=" "/>
	<ModelledSubgroup rscc="0.861" rsr="0.157" EDIAm="0.911" OPIA="100.000" owab="87.070" avgoccu="1.000" NatomsEDS="1" model="1" chain="A" resnum="207" said="C" ent="3" seq="." icode=" " resname="HOH" altcode=" "/>
	<ModelledSubgroup rscc="0.964" rsr="0.117" EDIAm="0.634" OPIA="0.000" owab="59.560" avgoccu="1.000" NatomsEDS="1" model="1" chain="A" resnum="208" said="C" ent="3" seq="." icode=" " resname="HOH" altcode=" "/>
	<ModelledEntityInstance bonds_rmsz="0.40" num_bonds_rmsz="286" angles_rmsz="0.76" num_angles_rmsz="442" relative_RSRZ_percentile="100.00" absolute_RSRZ_percentile="100.00" said="A" model="1" chain="A" ent="1"/>
	<programs>
		<program name="validation-pipeline" version="2.49" properties="PDB-resolution-low,pdbid,PDB-resolution,percentilebins,PDB-R,XMLcreationDate,attemptedValidationSteps,PDB-revision-number,PDB-revision-date,extended_pdbid,PDB-deposition-date,protein-DNA-RNA-entities,PDB-Rfree"/>
		<program name="molprobity" version="4-5-2 with Phenix2.0" properties="clashscore,num_angles_rmsz,bonds_rmsz,num_bonds_rmsz,bond-outlier,RestypesNotcheckedForBondAngleGeometry,angles_rmsz,angle-outlier,num-H-reduce,clash"/>
		<program name="xtriage" version="2.0" properties="TwinL2,TransNCS,TwinFraction,TwinL,acentric_outliers,xtriage_input_columns,DataAnisotropy,IoverSigma,WilsonBestimate,centric_outliers,numMillerIndices,WilsonBaniso"/>
		<program name="eds" version="3.0" properties="avgoccu,EDIAm,EDS_resolution,rscc,rsrz,percent-free-reflections,OPIA,relative_RSRZ_percentile,bulk_solvent_k,EDS_R,owab,bulk_solvent_b,absolute_RSRZ_percentile,Fo_Fc_correlation,DataCompleteness,EDS_resolution_low,rsr,CCP4version,num-free-reflections,density-fitnessVersion,percent-RSRZ-outliers,NatomsEDS"/>
		<program name="dcc" version="&quot;2.31  (2025-03-10))&quot;" properties="DCC_R,B_factor_type,DCC_Rfree,DCC_refinement_program"/>
		<program name="mogul" version="unknown" properties="mogul-ignore"/>
		<program name="buster-report" version="unknown" properties="no-ligands-for-buster-report"/>
		<program name="percentiles" version="20250101.v01 (using entries in the PDB archive January 1st 2025)" properties="numPDBids-absolute-percentile-clashscore,numPDBids-relative-percentile-clashscore,low-resol-relative-percentile-percent-RSRZ-outliers,numPDBids-absolute-percentile-DCC_Rfree,relative-percentile-DCC_Rfree,high-resol-relative-percentile-clashscore,absolute-percentile-DCC_Rfree,high-resol-relative-percentile-DCC_Rfree,high-resol-relative-percentile-percent-RSRZ-outliers,low-resol-relative-percentile-DCC_Rfree,numPDBids-relative-percentile-DCC_Rfree,numPDBids-relative-percentile-percent-RSRZ-outliers,absolute-percentile-percent-RSRZ-outliers,relative-percentile-percent-RSRZ-outliers,relative-percentile-clashscore,absolute-percentile-clashscore,low-resol-relative-percentile-clashscore,numPDBids-absolute-percentile-percent-RSRZ-outliers"/>
	</programs>
</wwPDB-validation-information>
