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<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="76" xmlns="https://uniprot.org/uniprot">
    <accession>C1DXY3</accession>
    <name>C1DXY3_MICCC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein HIRA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUN_106763</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="296587"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">RCC299 / NOUM17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the WD repeat HIR1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001323">
        <property type="protein sequence ID" value="ACO61333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_002500075.1">
        <property type="nucleotide sequence ID" value="XM_002500029.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1DXY3"/>
    <dbReference type="GeneID" id="8240786"/>
    <dbReference type="KEGG" id="mis:MICPUN_106763"/>
    <dbReference type="OrthoDB" id="1741719at2759"/>
    <dbReference type="Proteomes" id="UP000002009">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000417">
        <property type="term" value="C:HIR complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031491">
        <property type="term" value="F:nucleosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055410">
        <property type="entry name" value="Beta-prop_CAF1B_HIR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031120">
        <property type="entry name" value="HIR1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011494">
        <property type="entry name" value="HIRA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13831">
        <property type="entry name" value="MEMBER OF THE HIR1 FAMILY OF WD-REPEAT PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13831:SF0">
        <property type="entry name" value="PROTEIN HIRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24105">
        <property type="entry name" value="Beta-prop_CAF1B_HIR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07569">
        <property type="entry name" value="Hira"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0678">Repressor</keyword>
    <keyword evidence="7 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="6 10" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3 9 10" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="CAF1B/HIR1 beta-propeller" evidence="12">
        <location>
            <begin position="7"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="18"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="65"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="124"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="166"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Protein HIRA-like C-terminal" evidence="11">
        <location>
            <begin position="520"/>
            <end position="729"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF24105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACO61333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002009"/>
        </source>
    </evidence>
    <sequence length="796" mass="85537" checksum="B8D50EBC438016BF" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>C1DYC5</accession>
    <name>C1DYC5_MICCC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ATP-binding cassette superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUN_55988</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="296587"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">RCC299 / NOUM17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the ABC transporter superfamily. ABCF family. EF3 (TC 3.A.1.121) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP001323">
        <property type="protein sequence ID" value="ACO61402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_002500144.1">
        <property type="nucleotide sequence ID" value="XM_002500098.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1DYC5"/>
    <dbReference type="GeneID" id="8240859"/>
    <dbReference type="OMA" id="QYEGTML"/>
    <dbReference type="OrthoDB" id="495231at2759"/>
    <dbReference type="Proteomes" id="UP000002009">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03221">
        <property type="entry name" value="ABCF_EF-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000104">
        <property type="entry name" value="ATP-binding cassette sub-family F member 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000011">
        <property type="entry name" value="Putative ABC transporter ATP-binding component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050611">
        <property type="entry name" value="ABCF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211:SF15">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="24"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="335"/>
            <end position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00061344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACO61402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002009"/>
        </source>
    </evidence>
    <sequence length="555" mass="61801" checksum="81F53BC716187733" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>C1DYC6</accession>
    <name>C1DYC6_MICCC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ATP-binding cassette superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">MICPUN_55988</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="296587"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">RCC299 / NOUM17</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein biosynthesis; polypeptide chain elongation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001323">
        <property type="protein sequence ID" value="ACO61403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_002500145.1">
        <property type="nucleotide sequence ID" value="XM_002500099.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1DYC6"/>
    <dbReference type="GeneID" id="8240859"/>
    <dbReference type="OrthoDB" id="495231at2759"/>
    <dbReference type="Proteomes" id="UP000002009">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03221">
        <property type="entry name" value="ABCF_EF-3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050611">
        <property type="entry name" value="ABCF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047038">
        <property type="entry name" value="eEF3_chromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211:SF5">
        <property type="entry name" value="ELONGATION FACTOR 3A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="52"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="289"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACO61403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002009"/>
        </source>
    </evidence>
    <sequence length="560" mass="61102" checksum="1DC899C1F07FFEFC" modified="2009-05-26" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="85" xmlns="https://uniprot.org/uniprot">
    <accession>C1DYM9</accession>
    <name>C1DYM9_MICCC</name>
    <protein>
        <submittedName>
            <fullName evidence="11">TATA binding protein associated factor 5 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">MICPUN_55886</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="296587"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">RCC299 / NOUM17</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat TAF5 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001323">
        <property type="protein sequence ID" value="ACO61457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_002500199.1">
        <property type="nucleotide sequence ID" value="XM_002500153.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1DYM9"/>
    <dbReference type="GeneID" id="8240909"/>
    <dbReference type="KEGG" id="mis:MICPUN_55886"/>
    <dbReference type="OMA" id="HNHPVWD"/>
    <dbReference type="OrthoDB" id="674604at2759"/>
    <dbReference type="Proteomes" id="UP000002009">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08044">
        <property type="entry name" value="TAF5_NTD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.500">
        <property type="entry name" value="TFIID subunit TAF5, NTD2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007582">
        <property type="entry name" value="TFIID_NTD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037264">
        <property type="entry name" value="TFIID_NTD2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879:SF1">
        <property type="entry name" value="CANNONBALL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08513">
        <property type="entry name" value="LisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04494">
        <property type="entry name" value="TFIID_NTD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00667">
        <property type="entry name" value="LisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160897">
        <property type="entry name" value="Taf5 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3 8" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="TFIID subunit TAF5 NTD2" evidence="10">
        <location>
            <begin position="63"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="436"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="478"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="520"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="562"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="604"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="247"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="395"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="269"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACO61457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002009"/>
        </source>
    </evidence>
    <sequence length="706" mass="76954" checksum="9C09707AA2A8EB1B" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1E0T4</accession>
    <name>C1E0T4_MICCC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">General transcription and DNA repair factor IIH subunit TFB5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">MICPUN_79527</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="296587"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">RCC299 / NOUM17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the 7-subunit TFIIH core complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the TFB5 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001324">
        <property type="protein sequence ID" value="ACO61611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_002500353.1">
        <property type="nucleotide sequence ID" value="XM_002500307.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1E0T4"/>
    <dbReference type="GeneID" id="8241990"/>
    <dbReference type="KEGG" id="mis:MICPUN_79527"/>
    <dbReference type="OMA" id="DFREQNT"/>
    <dbReference type="OrthoDB" id="860at2759"/>
    <dbReference type="Proteomes" id="UP000002009">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000439">
        <property type="term" value="C:transcription factor TFIIH core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005675">
        <property type="term" value="C:transcription factor TFIIH holo complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006294">
        <property type="term" value="P:nucleotide-excision repair, preincision complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1220">
        <property type="entry name" value="TFB5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035935">
        <property type="entry name" value="TFB5-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009400">
        <property type="entry name" value="TFIIH_TTDA/Tfb5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28580">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28580:SF1">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06331">
        <property type="entry name" value="Tfb5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01395">
        <property type="entry name" value="Tbf5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142897">
        <property type="entry name" value="TFB5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU368032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACO61611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002009"/>
        </source>
    </evidence>
    <sequence length="75" mass="8718" checksum="75FC1A4B6734CBDA" modified="2009-05-26" version="1">MVSAVHGSLIETDIPCKVYILHINEQLPPAERFVIQDLDETHLLVQPHRLEYVKAEVKAWQQKNQFTPPTDLRQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1E2X6</accession>
    <name>C1E2X6_MICCC</name>
    <protein>
        <submittedName>
            <fullName evidence="6">High-mobility protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUN_57400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="296587"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">RCC299 / NOUM17</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001324">
        <property type="protein sequence ID" value="ACO61992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_002500734.1">
        <property type="nucleotide sequence ID" value="XM_002500688.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1E2X6"/>
    <dbReference type="GeneID" id="8241924"/>
    <dbReference type="OrthoDB" id="531008at2759"/>
    <dbReference type="Proteomes" id="UP000002009">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00084">
        <property type="entry name" value="HMG-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.30.10:FF:000016">
        <property type="entry name" value="FACT complex subunit SSRP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050342">
        <property type="entry name" value="HMGB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN DSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112:SF22">
        <property type="entry name" value="MITOCHONDRIAL TRANSCRIPTION FACTOR A, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00886">
        <property type="entry name" value="HIGHMOBLTY12"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="5">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="HMG box" evidence="5">
        <location>
            <begin position="78"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="3">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="3">
        <location>
            <begin position="78"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="51"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="59"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACO61992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002009"/>
        </source>
    </evidence>
    <sequence length="153" mass="16710" checksum="B3ACBB0329039A69" modified="2009-05-26" version="1">MMYCAEARPALKGMPVTQQAKQLGAQWKSLDPAVKSAFEEAAKAAKHAWELANPEAAKKKPAAKKARAPKAKKDPNAPKKPLSAYIIFTKERRSAVVAENPGLSLTEVTKELGARWKAIGAEEKSVFEAKAKKDKERYAVEMEAYEATQRAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1E771</accession>
    <name>C1E771_MICCC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Betaine/Carnitine/Choline transporter family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUN_90882</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="296587"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">RCC299 / NOUM17</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001326">
        <property type="protein sequence ID" value="ACO63929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_002502671.1">
        <property type="nucleotide sequence ID" value="XM_002502625.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1E771"/>
    <dbReference type="GeneID" id="8243586"/>
    <dbReference type="KEGG" id="mis:MICPUN_90882"/>
    <dbReference type="OMA" id="VHAWAIY"/>
    <dbReference type="OrthoDB" id="1045822at2759"/>
    <dbReference type="Proteomes" id="UP000002009">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018093">
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        <property type="entry name" value="HIGH-AFFINITY CHOLINE TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HIGH-AFFINITY CHOLINE TRANSPORT PROTEIN-RELATED"/>
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            <begin position="16"/>
            <end position="36"/>
        </location>
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            <end position="77"/>
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            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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            <begin position="157"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
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            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="325"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="394"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="463"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="569"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACO63929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002009"/>
        </source>
    </evidence>
    <sequence length="634" mass="69513" checksum="F7C165DED4F1EC0F" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="67" xmlns="https://uniprot.org/uniprot">
    <accession>C1EET8</accession>
    <name>C1EET8_MICCC</name>
    <protein>
        <submittedName>
            <fullName evidence="13">P-type ATPase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">MICPUN_62740</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="296587"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="14">RCC299 / NOUM17</strain>
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            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 11" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="152"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="12">
        <location>
            <begin position="33"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACO66589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002009"/>
        </source>
    </evidence>
    <sequence length="295" mass="30837" checksum="6B20B77B37E333A6" modified="2009-05-26" version="1" fragment="single">MRDFTSFLTRLFTWFISRSFSYSHPRVSLLPPPRSQVPLDGIVVHGSALVSIQHITGEALPVLKRVGDEVPAGAVNSDGALVVESIRSSEDSTPARIARLTEAAQNRRPAVSRLLDSVGDRYSKAILAVTALTMVCGPLVFGWPFLGRGGAMYRAFAFLSAAAPCALLMAPLVYVAAIGACARRGVLVRGGVTFDALAECGTVALDKTGTITSGRMKCVSIRRVFGDSDASANTTDFRSLSPLESPAALAIAASLERGATHPIARAVLDTAADQPPGALPAVAVSDFRVVAGCGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="66" xmlns="https://uniprot.org/uniprot">
    <accession>C1EH76</accession>
    <name>C1EH76_MICCC</name>
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        <submittedName>
            <fullName evidence="6">Mitochondrial carrier family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUN_64128</name>
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        <name type="scientific">Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="296587"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">RCC299 / NOUM17</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
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    <dbReference type="EMBL" id="CP001332">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="OMA" id="GPSGILM"/>
    <dbReference type="OrthoDB" id="250329at2759"/>
    <dbReference type="Proteomes" id="UP000002009">
        <property type="component" value="Chromosome 14"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46080:SF3">
        <property type="entry name" value="MITOCHONDRIAL SUBSTRATE CARRIER FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46080">
        <property type="entry name" value="MITOCHONDRIAL SUBSTRATE CARRIER FAMILY PROTEIN J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="4">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="4">
        <location>
            <begin position="84"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="4">
        <location>
            <begin position="249"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACO67248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002009"/>
        </source>
    </evidence>
    <sequence length="354" mass="37180" checksum="1CE2069B68B2D83B" modified="2009-05-26" version="1">MLYPLTVIKTRQMVDGSAVGSRPPPAMSIVKDIVKERGIPGLYRGFGTIVVGTLPIRFVYLSTLEVVKARARVVCEALDLPPMAHGIADAAGGATASMCSQVLGVPVDIISQRQMVQGVAVRAASGEGTVRLRGYRNGVHALREIIAAEGVRGLYRGFGASIATLVPGSAIWWGFYGTYQRVFWQLVPAELGGARVRDEGLNLATASKKGPALDKEDPSMEFKAAVARGMAASSARSETGVPAEPGEGTVIGVQVASGVCAGATSGFLTTPLDIVKTRLQVLSGPQGAASAGGGGGAVRHTFWSTAAELYREHGALGFFRGVRPRMTSVSIWGTTMVTTYEFLKRTSKIDDAEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>C1FD59</accession>
    <name>C1FD59_MICCC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Prasinophyte-specific protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PSP5</name>
        <name evidence="2" type="ORF">MICPUN_112701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="296587"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">RCC299 / NOUM17</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001574">
        <property type="protein sequence ID" value="ACO68728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_002507470.1">
        <property type="nucleotide sequence ID" value="XM_002507424.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1FD59"/>
    <dbReference type="GeneID" id="8250014"/>
    <dbReference type="OrthoDB" id="415315at2759"/>
    <dbReference type="Proteomes" id="UP000002009">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACO68728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002009"/>
        </source>
    </evidence>
    <sequence length="148" mass="16448" checksum="46B5C0CCEBE4B021" modified="2009-05-26" version="1">MLTLKRQSRSGSISRFLGNPVRIFHSLLFICALEVLFWSFCLFTCQSTVGWSGAARAYYTRETLNLKSTTGEALDAPVPAIDVRILELTLKAETAWHQRAFATLYAALNHLPLQQSSSVLAHSLLFPEKAFSTDSFSKSGAVLNFETE</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>C1FD89</accession>
    <name>C1FD89_MICCC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">SNRPD2|FCP1</name>
        <name evidence="1" type="ORF">MICPUN_54946</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="296587"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">RCC299 / NOUM17</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001574">
        <property type="protein sequence ID" value="ACO68745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1FD89"/>
    <dbReference type="KEGG" id="mis:MICPUN_54946"/>
    <dbReference type="OrthoDB" id="437526at2759"/>
    <dbReference type="Proteomes" id="UP000002009">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACO68745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002009"/>
        </source>
    </evidence>
    <sequence length="55" mass="6123" checksum="0E5995DF773DAC95" modified="2009-05-26" version="1">MVCEARSFGVIVIAQLARHKSPNCKETTKFCEGEFRQRDALGRAQDTAFCVKSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-04-02" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>C1FDG0</accession>
    <name>C1FDG0_MICCC</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Structural constituent of nuclear pore, nucleoporin 62</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">Nsp1</name>
        <name evidence="10" type="ORF">MICPUN_112724</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="296587"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">RCC299 / NOUM17</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleoporin NSP1/NUP62 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001574">
        <property type="protein sequence ID" value="ACO68383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_002507125.1">
        <property type="nucleotide sequence ID" value="XM_002507079.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1FDG0"/>
    <dbReference type="GeneID" id="8250061"/>
    <dbReference type="OMA" id="EWDNCIL"/>
    <dbReference type="OrthoDB" id="344345at2759"/>
    <dbReference type="Proteomes" id="UP000002009">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044613">
        <property type="term" value="C:nuclear pore central transport channel"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006405">
        <property type="term" value="P:RNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026010">
        <property type="entry name" value="NSP1/NUP62"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007758">
        <property type="entry name" value="Nucleoporin_NSP1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12084:SF0">
        <property type="entry name" value="NUCLEAR PORE GLYCOPROTEIN P62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12084">
        <property type="entry name" value="NUCLEAR PORE GLYCOPROTEIN P62-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05064">
        <property type="entry name" value="Nsp1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="7" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0811">Translocation</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Nucleoporin NSP1-like C-terminal" evidence="9">
        <location>
            <begin position="13"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACO68383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000002009"/>
        </source>
    </evidence>
    <sequence length="201" mass="22399" checksum="A977B7D8417A2EE9" modified="2009-05-26" version="1">MFSNIEADSKLKVPSEAQGKSVGEIVISWNTELESRTNFFLARTKGLTEWDSCIQKNKHILSALQIDLARVTSSQDRLERQLEILQLHQQEVDEALTIMESVAEQLGRTQHPTSGSSPQQTRTRHETIFNLAESVSASLSALGSALRHVTPSVYMAPAESDNKNCSIIKTQAHSFSDKILKAHLQTVLSVERKALQSQQLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1FDG6</accession>
    <name>C1FDG6_MICCC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Histone deacetylase complex protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SIN3</name>
        <name evidence="8" type="ORF">MICPUN_55021</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="296587"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">RCC299 / NOUM17</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP001574">
        <property type="protein sequence ID" value="ACO68387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_002507129.1">
        <property type="nucleotide sequence ID" value="XM_002507083.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1FDG6"/>
    <dbReference type="GeneID" id="8250448"/>
    <dbReference type="OrthoDB" id="10265969at2759"/>
    <dbReference type="Proteomes" id="UP000002009">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000118">
        <property type="term" value="C:histone deacetylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1160.11:FF:000002">
        <property type="entry name" value="Paired amphipathic helix protein SIN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1160.11:FF:000003">
        <property type="entry name" value="Paired amphipathic helix SIN3-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1160.11">
        <property type="entry name" value="Paired amphipathic helix"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013194">
        <property type="entry name" value="HDAC_interact_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003822">
        <property type="entry name" value="PAH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036600">
        <property type="entry name" value="PAH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039774">
        <property type="entry name" value="Sin3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031693">
        <property type="entry name" value="Sin3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12346:SF0">
        <property type="entry name" value="SIN3A, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12346">
        <property type="entry name" value="SIN3B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02671">
        <property type="entry name" value="PAH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08295">
        <property type="entry name" value="Sin3_corepress"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16879">
        <property type="entry name" value="Sin3a_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00761">
        <property type="entry name" value="HDAC_interact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47762">
        <property type="entry name" value="PAH2 domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51477">
        <property type="entry name" value="PAH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <feature type="domain" description="Histone deacetylase interacting" evidence="7">
        <location>
            <begin position="268"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="572"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="655"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1091"/>
            <end position="1124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="574"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="655"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1094"/>
            <end position="1112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACO68387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002009"/>
        </source>
    </evidence>
    <sequence length="1124" mass="127653" checksum="D17FE35F3D79CCDF" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>C1FDJ0</accession>
    <name>C1FDJ0_MICCC</name>
    <protein>
        <submittedName>
            <fullName evidence="3">JmjN/JmjC protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">MICPUN_113605</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="296587"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">RCC299 / NOUM17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the JARID1 histone demethylase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001574">
        <property type="protein sequence ID" value="ACO68397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_002507139.1">
        <property type="nucleotide sequence ID" value="XM_002507093.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1FDJ0"/>
    <dbReference type="GeneID" id="8250462"/>
    <dbReference type="OrthoDB" id="496616at2759"/>
    <dbReference type="Proteomes" id="UP000002009">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461:SF105">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1-ALPHA INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="2">
        <location>
            <begin position="103"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACO68397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000002009"/>
        </source>
    </evidence>
    <sequence length="277" mass="31630" checksum="84EAB1968BB0E7CA" modified="2009-05-26" version="1">MRRRLVRWSSSLPLGSLICDANPIRRPVQQLSRPYPAGSLSTVPLLDDLLGSEPFMMSGVGEGWPALYKWRDPAYLIVSTEDRVVPIECGEHFLHCTWTQKLMSMAEFMENYVRPEKAGYMAQHDIFEHIPRLLHDLDFPFFCSQGSCTRGHFPKKMIWIGPAGTISPLHTDPHANLFSQIAGYKYVRLYAPRCETNLYRNTTAKYCNSSQIELRGSLMGMLSEFPDFLNAPYVDCVLGPGDLLHIPPLHWHYVQSLTSSVSVTMWCRPKYVSRTND</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>C1FDM0</accession>
    <name>C1FDM0_MICCC</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MICPUN_77618</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="296587"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">RCC299 / NOUM17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CEF1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001574">
        <property type="protein sequence ID" value="ACO68410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_002507152.1">
        <property type="nucleotide sequence ID" value="XM_002507106.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1FDM0"/>
    <dbReference type="GeneID" id="8250085"/>
    <dbReference type="OMA" id="DTACARD"/>
    <dbReference type="OrthoDB" id="496424at2759"/>
    <dbReference type="Proteomes" id="UP000002009">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11659">
        <property type="entry name" value="SANT_CDC5_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000021">
        <property type="entry name" value="CDC5 cell division cycle 5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000091">
        <property type="entry name" value="CDC5 cell division cycle 5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047242">
        <property type="entry name" value="CDC5L/Cef1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
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        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047240">
        <property type="entry name" value="SANT_CDC5L_II"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45885">
        <property type="entry name" value="CELL DIVISION CYCLE 5-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45885:SF1">
        <property type="entry name" value="CELL DIVISION CYCLE 5-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="HTH myb-type" evidence="14">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="13">
        <location>
            <begin position="2"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="13">
        <location>
            <begin position="54"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="14">
        <location>
            <begin position="58"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="109"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="116"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="148"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ACO68410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000002009"/>
        </source>
    </evidence>
    <sequence length="160" mass="18528" checksum="750BCB3AFF285D3D" modified="2009-05-26" version="1" fragment="single">MRILIKGGVWKNTEDEILKAAVMKYGKNQWARISSLLVRKSAKQCKARWYEWLDPSIKKTEWTRQEDEKLLHLAKLMPTQWRTVAPIVGRTPAQCLERYEKLLDAACQQDSNDALDDPRRLKPGEIDPNPESKPARPDPVDMDEEEKEMLSEARARLANT</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>C1FDM2</accession>
    <name>C1FDM2_MICCC</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">MICPUN_51392</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="296587"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">RCC299 / NOUM17</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001574">
        <property type="protein sequence ID" value="ACO68412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_002507154.1">
        <property type="nucleotide sequence ID" value="XM_002507108.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1FDM2"/>
    <dbReference type="GeneID" id="8250086"/>
    <dbReference type="OrthoDB" id="10630938at2759"/>
    <dbReference type="Proteomes" id="UP000002009">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACO68412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002009"/>
        </source>
    </evidence>
    <sequence length="306" mass="33795" checksum="1CFEE24936641460" modified="2009-05-26" version="1">MEGDFPETLLPASRLQDRYFHGASNFDVSHEAPWRGKHKPPINFGHPRGYSEDPIREHCPSNFGKGGVRHYRRRLAGPISTSLETKLSYSAGGLCPDKGPIFYGHRNTIGTKSPGKPNQRRIPNLIQRQKDNFVGMSLPPPDPLPKPPPCAPPPYARDSDKAQKPMQWRINATNASHLFRDETEYSDDIKQQQPIRGQRVGKFSPAYEAGKRELPSWGWNPKKGKNDTSVPDVLGTHDFHNAGKGRKGRANSDLPEGEYAGATTKTIAGKEPFETVGVTPKHLGLIAESPKKPSIALPAHPSTQLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2023-02-22" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>C1FDM6</accession>
    <name>C1FDM6_MICCC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUN_107518</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="296587"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">RCC299 / NOUM17</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001574">
        <property type="protein sequence ID" value="ACO68416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_002507158.1">
        <property type="nucleotide sequence ID" value="XM_002507112.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1FDM6"/>
    <dbReference type="GeneID" id="8250089"/>
    <dbReference type="Proteomes" id="UP000002009">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACO68416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002009"/>
        </source>
    </evidence>
    <sequence length="90" mass="9426" checksum="1941561D5EC64433" modified="2009-05-26" version="1">MTAVPTLPPADFTARDAFSGGADILRASALKGPYVHFSRVGPPDAALDVDAYAPGTSSSGFELRQGRVMELAPLVEMRTPDAHVCPDAKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>C1FDN0</accession>
    <name>C1FDN0_MICCC</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">MICPUN_51395</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="296587"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">RCC299 / NOUM17</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001574">
        <property type="protein sequence ID" value="ACO68814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_002507556.1">
        <property type="nucleotide sequence ID" value="XM_002507510.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1FDN0"/>
    <dbReference type="GeneID" id="8250091"/>
    <dbReference type="OrthoDB" id="655030at2759"/>
    <dbReference type="Proteomes" id="UP000002009">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46972:SF1">
        <property type="entry name" value="FAD DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46972">
        <property type="entry name" value="MONOOXYGENASE ASQM-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="39"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="369"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACO68814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002009"/>
        </source>
    </evidence>
    <sequence length="512" mass="54845" checksum="249CF7CB557DC407" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>C1FDN3</accession>
    <name>C1FDN3_MICCC</name>
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        </recommendedName>
    </protein>
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        <name evidence="16" type="ORF">MICPUN_55092</name>
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        <name type="common">Picoplanktonic green alga</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
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                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
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                <person name="Bhattacharya D."/>
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                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
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        <reaction evidence="13">
            <text>a 1,2-diacyl-sn-glycerol + H2O = a 2-acylglycerol + a fatty acid + H(+)</text>
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            <dbReference type="ChEBI" id="CHEBI:15377"/>
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            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
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        </reaction>
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            <dbReference type="Rhea" id="RHEA:33276"/>
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    </comment>
    <comment type="cofactor">
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            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
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    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="OrthoDB" id="438440at2759"/>
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        <property type="component" value="Chromosome 1"/>
    </dbReference>
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        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
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            <begin position="233"/>
            <end position="397"/>
        </location>
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        </source>
    </evidence>
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        </source>
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        </source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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    <sequence length="569" mass="62618" checksum="7D7484D8AB127730" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>C1FDN6</accession>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
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                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
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                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
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                <person name="Wyss T."/>
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                <person name="Zhou K."/>
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                <person name="Bhattacharya D."/>
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            <dbReference type="PubMed" id="19359590"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ACO68425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
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        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-02-05" version="39" xmlns="https://uniprot.org/uniprot">
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            <taxon>Mamiellales</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
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                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
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                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
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            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">RCC299 / NOUM17</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_002507122.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1FDN7"/>
    <dbReference type="GeneID" id="8250094"/>
    <dbReference type="OMA" id="CKLRNIH"/>
    <dbReference type="OrthoDB" id="439917at2759"/>
    <dbReference type="Proteomes" id="UP000002009">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00102">
        <property type="entry name" value="IPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002909">
        <property type="entry name" value="IPT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01833">
        <property type="entry name" value="TIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IPT/TIG" evidence="1">
        <location>
            <begin position="19"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACO68426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000002009"/>
        </source>
    </evidence>
    <sequence length="100" mass="10863" checksum="A544DB97EED8EFE8" modified="2009-05-26" version="1">MVYVLQAGLHYTLLARALVGSLAPKRGTARGGTVLHLRGSGFFNSWDLRCKFGSIQVNIAYVSEAEIRCFSPSRAHGESDMQVILSGRHVCGASAYMFVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-12-14" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>C1FDS8</accession>
    <name>C1FDS8_MICCC</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">MICPUN_55161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="296587"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">RCC299 / NOUM17</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP001574">
        <property type="protein sequence ID" value="ACO68837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_002507579.1">
        <property type="nucleotide sequence ID" value="XM_002507533.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1FDS8"/>
    <dbReference type="GeneID" id="8250499"/>
    <dbReference type="Proteomes" id="UP000002009">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACO68837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000002009"/>
        </source>
    </evidence>
    <sequence length="104" mass="11677" checksum="424F33A8EB3C7E85" modified="2009-05-26" version="1">MDTYGRMGKPFLNFLKDVAALTARRASGNVNERTQAIYDSIDPPNELRNRIHLRNLALVHVALIISLMQRVAGSTVTNDRQHGARGGMYGAHEHYVQPYPVTNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1FFR0</accession>
    <name>C1FFR0_MICCC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Nucleobase:Cation symporter-2 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUN_94846</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="296587"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">RCC299 / NOUM17</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001575">
        <property type="protein sequence ID" value="ACO69125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_002507867.1">
        <property type="nucleotide sequence ID" value="XM_002507821.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1FFR0"/>
    <dbReference type="GeneID" id="8245503"/>
    <dbReference type="OMA" id="HVAVMIV"/>
    <dbReference type="OrthoDB" id="1641903at2759"/>
    <dbReference type="Proteomes" id="UP000002009">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042907">
        <property type="term" value="F:xanthine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006043">
        <property type="entry name" value="NCS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006042">
        <property type="entry name" value="Xan_ur_permease"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00801">
        <property type="entry name" value="ncs2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42810">
        <property type="entry name" value="PURINE PERMEASE C1399.01C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42810:SF2">
        <property type="entry name" value="PURINE PERMEASE C1399.01C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00860">
        <property type="entry name" value="Xan_ur_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="146"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="179"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="234"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="259"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="308"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="395"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="423"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="455"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="494"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACO69125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002009"/>
        </source>
    </evidence>
    <sequence length="534" mass="56741" checksum="28E1A077D0C345AB" modified="2009-05-26" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-06-18" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>C1FFV6</accession>
    <name>C1FFV6_MICCC</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein translocase subunit SecY</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">CpSecY</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">MICPUN_91438</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="296587"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">RCC299 / NOUM17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">The central subunit of the protein translocation channel SecYE. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Membrane</location>
            <topology evidence="1 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the SecY/SEC61-alpha family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001575">
        <property type="protein sequence ID" value="ACO69439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_002508181.1">
        <property type="nucleotide sequence ID" value="XM_002508135.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1FFV6"/>
    <dbReference type="GeneID" id="8245526"/>
    <dbReference type="OrthoDB" id="361383at2759"/>
    <dbReference type="Proteomes" id="UP000002009">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3370.10:FF:000001">
        <property type="entry name" value="Preprotein translocase subunit SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3370.10">
        <property type="entry name" value="SecY subunit domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01465">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026593">
        <property type="entry name" value="SecY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002208">
        <property type="entry name" value="SecY/SEC61-alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030659">
        <property type="entry name" value="SecY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023201">
        <property type="entry name" value="SecY_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00967">
        <property type="entry name" value="3a0501s007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10906">
        <property type="entry name" value="SECY/SEC61-ALPHA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00344">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004557">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00303">
        <property type="entry name" value="SECYTRNLCASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103491">
        <property type="entry name" value="Preprotein translocase SecY subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00755">
        <property type="entry name" value="SECY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00756">
        <property type="entry name" value="SECY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 12 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="64"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="251"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="292"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="351"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="375"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00039733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00055151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ACO69439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000002009"/>
        </source>
    </evidence>
    <sequence length="423" mass="45432" checksum="9B451749E2C00F0B" modified="2009-05-26" version="1">MNDFMNSKLPGKIGTVLLLLILSRVGTYIPISGVDRDAFAESLQGGGNVLGYVDTLTGGSISKLGIFSLGIVPYINSSIIFQLLTSVFPSLKKLQKEEGEAGRRKFQQYQRYGALGFAVVQAVGQCLYVRPFVEDFNLGWLVESSAVLTAGAMILLYIGEVLTELKLGNGTSLLIFTNIISSLPSSFGQTLSQASEKGDAATVLPVFFGAFFLTTLGIVYVQEAERKIPMNYSTRFQAGGLAKSSYLPFKVNSAGVMPIIFASSLLALPATLARFAPNPVIIGAAKAVYPGGVAYVPVNIALICFFNYFYTFLQLEPKDVADQLKRQGASIPGVRPGAATSGYITRVLERLSILGSVFLGFLALAPTAVEGITGLTTFRGFAGTSLLILVGVATDTTRKVRSEIVMSRYDTSLDDFYKDMPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>C1FFY6</accession>
    <name>C1FFY6_MICCC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GrpE protein homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">MICPUN_97757</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="296587"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">RCC299 / NOUM17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the GrpE family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001575">
        <property type="protein sequence ID" value="ACO69163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_002507905.1">
        <property type="nucleotide sequence ID" value="XM_002507859.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1FFY6"/>
    <dbReference type="GeneID" id="8245829"/>
    <dbReference type="KEGG" id="mis:MICPUN_97757"/>
    <dbReference type="OMA" id="QHELICH"/>
    <dbReference type="OrthoDB" id="201635at2759"/>
    <dbReference type="Proteomes" id="UP000002009">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001405">
        <property type="term" value="C:PAM complex, Tim23 associated import motor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000774">
        <property type="term" value="F:adenyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00446">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.22.10:FF:000002">
        <property type="entry name" value="GrpE protein homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.22.10">
        <property type="entry name" value="Head domain of nucleotide exchange factor GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01151">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000740">
        <property type="entry name" value="GrpE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013805">
        <property type="entry name" value="GrpE_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009012">
        <property type="entry name" value="GrpE_head"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21237">
        <property type="entry name" value="GRPE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21237:SF23">
        <property type="entry name" value="GRPE PROTEIN HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01025">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00773">
        <property type="entry name" value="GRPEPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58014">
        <property type="entry name" value="Coiled-coil domain of nucleotide exchange factor GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51064">
        <property type="entry name" value="Head domain of nucleotide exchange factor GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01071">
        <property type="entry name" value="GRPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="10"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="24"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACO69163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000002009"/>
        </source>
    </evidence>
    <sequence length="216" mass="23687" checksum="85AD00B402695A07" modified="2009-05-26" version="1">MIAATGPTSRQHDVPRVEKKEDDKAGEDDETEGAEDGEDVNEDEVADEEVQKLTAELSEKTAQVKDLNDKLLRTLADMENLRERTRRQAETAEKFAIQGFCKDLLDVADNLARASATVDPEALETETDAANIKNVLASLHEGVLMVEKQLMSTFGKHGVVKFDPAEGDPFNPNDHMALFNVPKGEKEAGTVAAVTKVGYKLHDRVIRPAEVGVFQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2025-10-08" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>C1FHN6</accession>
    <name>C1FHN6_MICCC</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Polycomb group protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">MICPUN_62144</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="296587"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">RCC299 / NOUM17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat ESC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP001576">
        <property type="protein sequence ID" value="ACO70132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_002508874.1">
        <property type="nucleotide sequence ID" value="XM_002508828.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1FHN6"/>
    <dbReference type="GeneID" id="8246872"/>
    <dbReference type="OMA" id="VWEMDPS"/>
    <dbReference type="OrthoDB" id="7318948at2759"/>
    <dbReference type="Proteomes" id="UP000002009">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051243">
        <property type="entry name" value="PcG_WD-repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10253">
        <property type="entry name" value="POLYCOMB PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="115"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="214"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="403"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="409"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="434"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ACO70132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000002009"/>
        </source>
    </evidence>
    <sequence length="449" mass="47940" checksum="FC5C825DE37F3BC3" modified="2009-05-26" version="1">MRYNEGRYKLSCVVRQDPADHVYCCALNTVHLAHADKLATTAGPRAYVYRLTPDGGVKLMQCYVDEDDEEDYFACCWCASAVPERSGRPMLAVAGGYKGVVRVIDCVSRVVKVNLRGHGGGVNDVKAHPLRPHLLLTASKDESCRLWNLDSGACVAVFAGEFGHRNEVLSVDFKPGVDPYDDAPGAGDVVFVSGAMDNQIKVWSTRGYPGLVRRSDGWRKGSTASGDSPPGESPPGGGEKTANIAFPTAHVQTPTFSSHKVHGNYVDCVRWFGDLVLSKSVENVVTLFQPRLGGVGDLVTGSGFRKVQDFPLRKCDIWFMRFALAPDATHMCCGNTAGEVFVWRMGGGGGGHTAHTTASATLAHKRCVKAVRQTAMTADGRIVIAACDEGTVWRWDLVDAGAGGGSVGGEKRARTEKDDATDEKGRGDEGVDGGDVVTGASGDTIEILD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1KR48</accession>
    <name>C1KR48_MICCC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Small ribosomal subunit protein uS11c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rps11</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="296587"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="9"/>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">RCC299 / NOUM17</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="7">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Plastid</location>
            <location evidence="7">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the universal ribosomal protein uS11 family.</text>
    </comment>
    <dbReference type="EMBL" id="FJ858267">
        <property type="protein sequence ID" value="ACO55550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_002808626.1">
        <property type="nucleotide sequence ID" value="NC_012575.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1KR48"/>
    <dbReference type="OMA" id="TAVDQGM"/>
    <dbReference type="Proteomes" id="UP000002009">
        <property type="component" value="Chloroplast Pltd"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.80:FF:000010">
        <property type="entry name" value="30S ribosomal protein S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.80">
        <property type="entry name" value="Ribosomal protein S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01310">
        <property type="entry name" value="Ribosomal_uS11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001971">
        <property type="entry name" value="Ribosomal_uS11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019981">
        <property type="entry name" value="Ribosomal_uS11_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018102">
        <property type="entry name" value="Ribosomal_uS11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036967">
        <property type="entry name" value="Ribosomal_uS11_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003698">
        <property type="entry name" value="PRK05309.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03632">
        <property type="entry name" value="uS11_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11759">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S14/30S RIBOSOMAL PROTEIN S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00411">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002131">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53137">
        <property type="entry name" value="Translational machinery components"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00054">
        <property type="entry name" value="RIBOSOMAL_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="9" id="KW-0934">Plastid</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 7" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACO55550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002009"/>
        </source>
    </evidence>
    <sequence length="130" mass="14016" checksum="9A27113E05F7B36C" modified="2009-05-26" version="1">MASKQRKSVQKKARRKVQRGVVHILATFNNTLVTISDRSGMVIASSSSGACGFRGARKGTPFAAQTAAEEAARKSLDYGLKYVDVMVKGPGAGREMAIRALQQLGLGITLIRDVTPLPHNGCRPPKKRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1KR50</accession>
    <name>C1KR50_MICCC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein uS8c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rps8</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="296587"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="6"/>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">RCC299 / NOUM17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Plastid</location>
            <location evidence="4">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the universal ribosomal protein uS8 family.</text>
    </comment>
    <dbReference type="EMBL" id="FJ858267">
        <property type="protein sequence ID" value="ACO55552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_002808628.1">
        <property type="nucleotide sequence ID" value="NC_012575.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1KR50"/>
    <dbReference type="OMA" id="NSAYHDT"/>
    <dbReference type="Proteomes" id="UP000002009">
        <property type="component" value="Chloroplast Pltd"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.10:FF:000001">
        <property type="entry name" value="30S ribosomal protein S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01302_B">
        <property type="entry name" value="Ribosomal_uS8_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000630">
        <property type="entry name" value="Ribosomal_uS8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047863">
        <property type="entry name" value="Ribosomal_uS8_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035987">
        <property type="entry name" value="Ribosomal_uS8_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001109">
        <property type="entry name" value="PRK00136.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11758">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S15A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00410">
        <property type="entry name" value="Ribosomal_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56047">
        <property type="entry name" value="Ribosomal protein S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00053">
        <property type="entry name" value="RIBOSOMAL_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="6" id="KW-0934">Plastid</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACO55552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002009"/>
        </source>
    </evidence>
    <sequence length="122" mass="13594" checksum="22EAEF1CAF66ED4A" modified="2009-05-26" version="1">MINDTIADMLTRLRNAQLANKTSVALRATRVTRNIAQLLFQEGFLSNIEPETNGMFEVTLKRSVKTFKRVSTPGVRVYVNHKELPRVLNGMGIAIISTSQGIMTEKKARALGIGGEVLCYLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="58" xmlns="https://uniprot.org/uniprot">
    <accession>C1KR51</accession>
    <name>C1KR51_MICCC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 9">Large ribosomal subunit protein uL5c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">rpl5</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="296587"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="13"/>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">RCC299 / NOUM17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Binds 5S rRNA, forms part of the central protuberance of the 50S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 9">Part of the 50S ribosomal subunit; contacts the 5S rRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Plastid</location>
            <location evidence="2 9">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9 10">Belongs to the universal ribosomal protein uL5 family.</text>
    </comment>
    <dbReference type="EMBL" id="FJ858267">
        <property type="protein sequence ID" value="ACO55553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_002808629.1">
        <property type="nucleotide sequence ID" value="NC_012575.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1KR51"/>
    <dbReference type="OMA" id="FQIREDM"/>
    <dbReference type="Proteomes" id="UP000002009">
        <property type="component" value="Chloroplast Pltd"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1440.10:FF:000001">
        <property type="entry name" value="50S ribosomal protein L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01333_B">
        <property type="entry name" value="Ribosomal_uL5_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002132">
        <property type="entry name" value="Ribosomal_uL5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020930">
        <property type="entry name" value="Ribosomal_uL5_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031309">
        <property type="entry name" value="Ribosomal_uL5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022803">
        <property type="entry name" value="Ribosomal_uL5_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031310">
        <property type="entry name" value="Ribosomal_uL5_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000585">
        <property type="entry name" value="PRK00010.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11994">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00281">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00673">
        <property type="entry name" value="Ribosomal_L5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002161">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55282">
        <property type="entry name" value="RL5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="13" id="KW-0934">Plastid</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6 9 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="9" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL5 N-terminal" evidence="11">
        <location>
            <begin position="25"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL5 C-terminal" evidence="12">
        <location>
            <begin position="85"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00035210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACO55553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000002009"/>
        </source>
    </evidence>
    <sequence length="184" mass="20803" checksum="CC6D78D523F740EE" modified="2009-05-26" version="1">MIQRLQNLYLTKVRDTLTEQFQYKNTHEIPRLEKIVINRGVGDASQNAKLLESLSNELTVLAGQAPVVKRSKKAIAGFQIREDMPIGLSVTLRGDRMYAFFDRLVNLALPRIRDFQGINPKGFDGQGNFNIGLDEQLMFPELSYDTIDQIRGMDIAIVTSSQTDQEGKALLKELGMPFREKATK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>C1KR52</accession>
    <name>C1KR52_MICCC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein uL14c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpl14</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="296587"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="9"/>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">RCC299 / NOUM17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 8">Binds to 23S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 8">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6 8">Plastid</location>
            <location evidence="6 8">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the universal ribosomal protein uL14 family.</text>
    </comment>
    <dbReference type="EMBL" id="FJ858267">
        <property type="protein sequence ID" value="ACO55554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_002808630.1">
        <property type="nucleotide sequence ID" value="NC_012575.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1KR52"/>
    <dbReference type="OMA" id="HTVQREN"/>
    <dbReference type="Proteomes" id="UP000002009">
        <property type="component" value="Chloroplast Pltd"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00337">
        <property type="entry name" value="Ribosomal_uL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.150.20:FF:000001">
        <property type="entry name" value="50S ribosomal protein L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.150.20">
        <property type="entry name" value="Ribosomal protein L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01367">
        <property type="entry name" value="Ribosomal_uL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000218">
        <property type="entry name" value="Ribosomal_uL14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005745">
        <property type="entry name" value="Ribosomal_uL14_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019972">
        <property type="entry name" value="Ribosomal_uL14_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036853">
        <property type="entry name" value="Ribosomal_uL14_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01067">
        <property type="entry name" value="rplN_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761">
        <property type="entry name" value="50S/60S RIBOSOMAL PROTEIN L14/L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL14M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00238">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01374">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50193">
        <property type="entry name" value="Ribosomal protein L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00049">
        <property type="entry name" value="RIBOSOMAL_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="8 9" id="KW-0934">Plastid</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6 8" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACO55554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002009"/>
        </source>
    </evidence>
    <sequence length="119" mass="13357" checksum="47EA23CA9A36DE40" modified="2009-05-26" version="1">MIQPQTYLEVADNSGARKLMCIRVLNRQYANIGDVIIAVVKEALPNMPVKRSDVVRAVVVRTAHTVQRENGMSIRFDENAAVIINKEGNPRGTRVFGPIARELRERDFMKIVSLAPEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>C1KR54</accession>
    <name>C1KR54_MICCC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Small ribosomal subunit protein uS3c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rps3</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="296587"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="12"/>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">RCC299 / NOUM17</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="7 10">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7 10">Plastid</location>
            <location evidence="7 10">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 9">Belongs to the universal ribosomal protein uS3 family.</text>
    </comment>
    <dbReference type="EMBL" id="FJ858267">
        <property type="protein sequence ID" value="ACO55556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_002808632.1">
        <property type="nucleotide sequence ID" value="NC_012575.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1KR54"/>
    <dbReference type="OMA" id="THRSQWF"/>
    <dbReference type="Proteomes" id="UP000002009">
        <property type="component" value="Chloroplast Pltd"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02412">
        <property type="entry name" value="KH-II_30S_S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.20:FF:000001">
        <property type="entry name" value="30S ribosomal protein S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.32">
        <property type="entry name" value="Ribosomal protein S3, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01309_B">
        <property type="entry name" value="Ribosomal_uS3_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036419">
        <property type="entry name" value="Ribosomal_S3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057258">
        <property type="entry name" value="Ribosomal_uS3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005704">
        <property type="entry name" value="Ribosomal_uS3_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001351">
        <property type="entry name" value="Ribosomal_uS3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018280">
        <property type="entry name" value="Ribosomal_uS3_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01009">
        <property type="entry name" value="rpsC_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11760">
        <property type="entry name" value="30S/40S RIBOSOMAL PROTEIN S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11760:SF19">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00189">
        <property type="entry name" value="Ribosomal_S3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="Prokaryotic type KH domain (KH-domain type II)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54821">
        <property type="entry name" value="Ribosomal protein S3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50823">
        <property type="entry name" value="KH_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00548">
        <property type="entry name" value="RIBOSOMAL_S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="10 12" id="KW-0934">Plastid</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 7 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="KH type-2" evidence="11">
        <location>
            <begin position="39"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACO55556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000002009"/>
        </source>
    </evidence>
    <sequence length="211" mass="23440" checksum="622B6ABBEB1CCA3D" modified="2009-05-26" version="1">MGQKVHPLGFRIGVTQTHRSQWFAKPKDYANLVKEDLIIRDYVAKNLTDASISRVNISRQVDRIEIEFFTARPRALVGAKGEALVKVREALKAKLPAHRSVALYVTKTVQPEVDAVCIAENIAMQLEKRAPFRRTIRQALRSAQKAGAVGIKVQIAGRLNGAEIARSEWAREGRVPLHTISADIDYATARALTVYGILGIKVWVCKGDNKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>C1KR60</accession>
    <name>C1KR60_MICCC</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein uS2c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rps2</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="296587"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="6"/>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">RCC299 / NOUM17</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Plastid</location>
            <location evidence="4">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the universal ribosomal protein uS2 family.</text>
    </comment>
    <dbReference type="EMBL" id="FJ858267">
        <property type="protein sequence ID" value="ACO55562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_002808638.1">
        <property type="nucleotide sequence ID" value="NC_012575.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1KR60"/>
    <dbReference type="OMA" id="PYIFMEK"/>
    <dbReference type="Proteomes" id="UP000002009">
        <property type="component" value="Chloroplast Pltd"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01425">
        <property type="entry name" value="RPS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10490">
        <property type="entry name" value="Glucose-6-phosphate isomerase like protein, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.610">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00291_B">
        <property type="entry name" value="Ribosomal_uS2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001865">
        <property type="entry name" value="Ribosomal_uS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005706">
        <property type="entry name" value="Ribosomal_uS2_bac/mit/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018130">
        <property type="entry name" value="Ribosomal_uS2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023591">
        <property type="entry name" value="Ribosomal_uS2_flav_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01011">
        <property type="entry name" value="rpsB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12534">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S2 PROKARYOTIC AND ORGANELLAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12534:SF0">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00318">
        <property type="entry name" value="Ribosomal_S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00395">
        <property type="entry name" value="RIBOSOMALS2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52313">
        <property type="entry name" value="Ribosomal protein S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00962">
        <property type="entry name" value="RIBOSOMAL_S2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00963">
        <property type="entry name" value="RIBOSOMAL_S2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="6" id="KW-0934">Plastid</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ACO55562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000002009"/>
        </source>
    </evidence>
    <sequence length="215" mass="23879" checksum="AEBC5B54284D1D7D" modified="2009-05-26" version="1">MTKLEALLEAGVHFGHQVGRWNSKMAPYIHETKNGVHILDLVQTLDDLEKARPVLKRAKNVLFVGTRPQIAPIIETTAQKVNGHYVSTRWVGGLLTNWKTMSMCLQKLNRLDKQLSEDGKASGLSKKAILQLKKQRARLEKFFGGLRGLSELPDLVVIVGQPHEKNAVNECQRLGIPTITLLDSNCDPTMSTYGITANDDSTRSVEIILESLIAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="59" xmlns="https://uniprot.org/uniprot">
    <accession>C1KR66</accession>
    <name>C1KR66_MICCC</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 9">Small ribosomal subunit protein uS12c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">rps12</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="296587"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="11"/>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">RCC299 / NOUM17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 9">With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 9">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Plastid</location>
            <location evidence="9">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9 10">Belongs to the universal ribosomal protein uS12 family.</text>
    </comment>
    <dbReference type="EMBL" id="FJ858267">
        <property type="protein sequence ID" value="ACO55568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_002808644.1">
        <property type="nucleotide sequence ID" value="NC_012575.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1KR66"/>
    <dbReference type="OMA" id="HRESRYM"/>
    <dbReference type="Proteomes" id="UP000002009">
        <property type="component" value="Chloroplast Pltd"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03368">
        <property type="entry name" value="Ribosomal_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000001">
        <property type="entry name" value="30S ribosomal protein S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00403_B">
        <property type="entry name" value="Ribosomal_uS12_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006032">
        <property type="entry name" value="Ribosomal_uS12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005679">
        <property type="entry name" value="Ribosomal_uS12_bac"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00981">
        <property type="entry name" value="rpsL_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11652">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S12 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00164">
        <property type="entry name" value="Ribosom_S12_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002133">
        <property type="entry name" value="Ribosomal_S12/S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01034">
        <property type="entry name" value="RIBOSOMALS12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00055">
        <property type="entry name" value="RIBOSOMAL_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="11" id="KW-0934">Plastid</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 9 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 9" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00040813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACO55568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002009"/>
        </source>
    </evidence>
    <sequence length="124" mass="13782" checksum="DAA6290B6B7F8CEA" modified="2009-05-26" version="1">MPTIQQLIRSQRMKIEKKTKSPALQSCPQRRGICTRVYTTTPKKPNSALRKVARVRLTTGIEVTAYIPGIGHNLQEHSVVLVRGGRVKDLPGVRYHIVRGSLDTAGVKGRLQGRSKYGVKRPKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="65" xmlns="https://uniprot.org/uniprot">
    <accession>C1KR69</accession>
    <name>C1KR69_MICCC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Small ribosomal subunit protein uS4c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rps4</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="296587"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <geneLocation type="chloroplast" evidence="11"/>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2009" name="Science" volume="324" first="268" last="272">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Parker M.S."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
            <dbReference type="PubMed" id="19359590"/>
            <dbReference type="DOI" id="10.1126/science.1167222"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">RCC299 / NOUM17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="7">With S5 and S12 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Plastid</location>
            <location evidence="7">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the universal ribosomal protein uS4 family.</text>
    </comment>
    <dbReference type="EMBL" id="FJ858267">
        <property type="protein sequence ID" value="ACO55571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_002808647.1">
        <property type="nucleotide sequence ID" value="NC_012575.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1KR69"/>
    <dbReference type="OMA" id="QLVVELY"/>
    <dbReference type="OrthoDB" id="2443at2759"/>
    <dbReference type="Proteomes" id="UP000002009">
        <property type="component" value="Chloroplast Pltd"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.290.10:FF:000001">
        <property type="entry name" value="30S ribosomal protein S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1050.10:FF:000002">
        <property type="entry name" value="30S ribosomal protein S4, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1050.10">
        <property type="entry name" value="Ribosomal Protein S4 Delta 41, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="entry name" value="RNA-binding S4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01306_B">
        <property type="entry name" value="Ribosomal_uS4_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022801">
        <property type="entry name" value="Ribosomal_uS4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005709">
        <property type="entry name" value="Ribosomal_uS4_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001912">
        <property type="entry name" value="Ribosomal_uS4_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003717">
        <property type="entry name" value="PRK05327.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01017">
        <property type="entry name" value="rpsD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831">
        <property type="entry name" value="30S 40S RIBOSOMAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831:SF4">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US4M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00163">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01390">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55174">
        <property type="entry name" value="Alpha-L RNA-binding motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="11" id="KW-0934">Plastid</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7 11" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 7 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS4 N-terminal" evidence="10">
        <location>
            <begin position="3"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="RNA-binding S4" evidence="9">
        <location>
            <begin position="92"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ACO55571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000002009"/>
        </source>
    </evidence>
    <sequence length="198" mass="22102" checksum="152222794A77FC3C" modified="2009-05-26" version="1">MARYRGPRVKIVRRLGELPGLTTKVPNRTYGPGQHGQATSTGKLTQFRVRLQEKQKLRYNYGISEKQLLTYVRRARRAKGPTGEVLLQMLEMRLDSIVYRLGFAPTIRAARQYVSHGLITVNGQTVNIPSYNCLPGETIASTSNPVVENCKTFGGAVPSHLTVDTAKTTGKIQRVITRSQIALTVNELLIIEFYSRKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>C1KRG3</accession>
    <name>C1KRG3_MICCC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal protein S7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rps7</name>
        <name evidence="5" type="ORF">MicpuN_mit29</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="296587"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <geneLocation type="mitochondrion" evidence="5"/>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-03" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Micromonas genome consortium"/>
                <person name="Robbens S."/>
                <person name="Rombauts S."/>
                <person name="Lucas S."/>
                <person name="Glavina del Rio T."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Pitluck S."/>
                <person name="Van de Peer Y."/>
                <person name="Zhou K."/>
                <person name="Grimwood J."/>
                <person name="Grigoriev I.V."/>
                <person name="Cuvelier M.L."/>
                <person name="Worden A.Z."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">RCC299 / NOUM17</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2009-04" db="EMBL/GenBank/DDBJ databases">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.-H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Schnitzler Parker M."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F.X."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">RCC299 / NOUM17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS7 family.</text>
    </comment>
    <dbReference type="EMBL" id="FJ859351">
        <property type="protein sequence ID" value="ACO55595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_002860131.1">
        <property type="nucleotide sequence ID" value="NC_012643.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1KRG3"/>
    <dbReference type="GeneID" id="7804341"/>
    <dbReference type="KEGG" id="mis:MicpuN_mit29"/>
    <dbReference type="OMA" id="ISSMWRI"/>
    <dbReference type="OrthoDB" id="35139at2759"/>
    <dbReference type="Proteomes" id="UP000002009">
        <property type="component" value="Mitochondrion MT"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15484">
        <property type="entry name" value="uS7_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.455.10">
        <property type="entry name" value="Ribosomal protein S7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000235">
        <property type="entry name" value="Ribosomal_uS7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023798">
        <property type="entry name" value="Ribosomal_uS7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036823">
        <property type="entry name" value="Ribosomal_uS7_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034643">
        <property type="entry name" value="RPS7_plant"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11205">
        <property type="entry name" value="RIBOSOMAL PROTEIN S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00177">
        <property type="entry name" value="Ribosomal_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002122">
        <property type="entry name" value="RPS7p_RPS7a_RPS5e_RPS7o"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47973">
        <property type="entry name" value="Ribosomal protein S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS7" evidence="4">
        <location>
            <begin position="17"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACO55595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002009"/>
        </source>
    </evidence>
    <sequence length="181" mass="20672" checksum="19C02E266571F6AB" modified="2009-05-26" version="1" fragment="single">LHSVDILTAPIYYTISKVEKSSDSISDIPILAKLTSFLTKKGHKTRAAGITFKVLHILENLQSQDTLRVHPIEIIQTALQNAKPVFELRKARIGGNTQFVPASLSLNKQENRAIRTIISNANVKHKKGIKAKNPMMYTFAYSLAVEFFDAYKNQGKACQEKNLLHKQAENNRQYIHKRWWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>C1KRI0</accession>
    <name>C1KRI0_MICCC</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribosomal protein S14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rps14</name>
        <name evidence="4" type="ORF">MicpuN_mit65</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="296587"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <geneLocation type="mitochondrion" evidence="4"/>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2009-03" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Micromonas genome consortium"/>
                <person name="Robbens S."/>
                <person name="Rombauts S."/>
                <person name="Lucas S."/>
                <person name="Glavina del Rio T."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Pitluck S."/>
                <person name="Van de Peer Y."/>
                <person name="Zhou K."/>
                <person name="Grimwood J."/>
                <person name="Grigoriev I.V."/>
                <person name="Cuvelier M.L."/>
                <person name="Worden A.Z."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">RCC299 / NOUM17</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2009-04" db="EMBL/GenBank/DDBJ databases">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.-H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Schnitzler Parker M."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F.X."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">RCC299 / NOUM17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS14 family.</text>
    </comment>
    <dbReference type="EMBL" id="FJ859351">
        <property type="protein sequence ID" value="ACO55612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_002860148.1">
        <property type="nucleotide sequence ID" value="NC_012643.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1KRI0"/>
    <dbReference type="GeneID" id="7804377"/>
    <dbReference type="KEGG" id="mis:MicpuN_mit65"/>
    <dbReference type="OMA" id="ISTTWRM"/>
    <dbReference type="OrthoDB" id="413436at2759"/>
    <dbReference type="Proteomes" id="UP000002009">
        <property type="component" value="Mitochondrion MT"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.1480:FF:000001">
        <property type="entry name" value="30S ribosomal protein S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001209">
        <property type="entry name" value="Ribosomal_uS14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018271">
        <property type="entry name" value="Ribosomal_uS14_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006477">
        <property type="entry name" value="PRK08881.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19836">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19836:SF19">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US14M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00253">
        <property type="entry name" value="Ribosomal_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00527">
        <property type="entry name" value="RIBOSOMAL_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACO55612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000002009"/>
        </source>
    </evidence>
    <sequence length="99" mass="11724" checksum="6E6AA63123E676A2" modified="2009-05-26" version="1">MKRRNLKDVQKRALFSRVEHKRNILRAMLKDRTLPQHIRFHMSVELNSLPRNSIPTKIKNRCVQTGRSKGVYRLLKMSRIRMRELMAMGALPGIKKASW</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="51" xmlns="https://uniprot.org/uniprot">
    <accession>C1KRI3</accession>
    <name>C1KRI3_MICCC</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal protein L16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpl16</name>
        <name evidence="5" type="ORF">MicpuN_mit68</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="296587"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <geneLocation type="mitochondrion" evidence="5"/>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2009-03" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Micromonas genome consortium"/>
                <person name="Robbens S."/>
                <person name="Rombauts S."/>
                <person name="Lucas S."/>
                <person name="Glavina del Rio T."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Pitluck S."/>
                <person name="Van de Peer Y."/>
                <person name="Zhou K."/>
                <person name="Grimwood J."/>
                <person name="Grigoriev I.V."/>
                <person name="Cuvelier M.L."/>
                <person name="Worden A.Z."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">RCC299 / NOUM17</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2009-04" db="EMBL/GenBank/DDBJ databases">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.-H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Schnitzler Parker M."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F.X."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">RCC299 / NOUM17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL16 family.</text>
    </comment>
    <dbReference type="EMBL" id="FJ859351">
        <property type="protein sequence ID" value="ACO55615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_002860151.1">
        <property type="nucleotide sequence ID" value="NC_012643.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1KRI3"/>
    <dbReference type="GeneID" id="7804380"/>
    <dbReference type="KEGG" id="mis:MicpuN_mit68"/>
    <dbReference type="OMA" id="WICRIQK"/>
    <dbReference type="OrthoDB" id="1850746at2759"/>
    <dbReference type="Proteomes" id="UP000002009">
        <property type="component" value="Mitochondrion MT"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01433">
        <property type="entry name" value="Ribosomal_L16_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1170.10:FF:000001">
        <property type="entry name" value="50S ribosomal protein L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.10">
        <property type="entry name" value="Ribosomal protein L10e/L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047873">
        <property type="entry name" value="Ribosomal_uL16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000114">
        <property type="entry name" value="Ribosomal_uL16_bact-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020798">
        <property type="entry name" value="Ribosomal_uL16_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016180">
        <property type="entry name" value="Ribosomal_uL16_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036920">
        <property type="entry name" value="Ribosomal_uL16_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01164">
        <property type="entry name" value="rplP_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12220">
        <property type="entry name" value="50S/60S RIBOSOMAL PROTEIN L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12220:SF13">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL16M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00252">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00060">
        <property type="entry name" value="RIBOSOMALL16"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54686">
        <property type="entry name" value="Ribosomal protein L16p/L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00586">
        <property type="entry name" value="RIBOSOMAL_L16_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00701">
        <property type="entry name" value="RIBOSOMAL_L16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ACO55615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000002009"/>
        </source>
    </evidence>
    <sequence length="133" mass="15017" checksum="BFADDD6A6D03AD5B" modified="2009-05-26" version="1">MLQPKRTSFRKMHKGRVSGIKKQTLHFGSFGLQACSTGKLKASVIESMRRVMTRKLKRQGQIWIRIFPDIVVSEKPAEVRMGKGKGSPSYWICRIQKGQVLFELDGVPKSLALQALKLALHKCPIPSHILSLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2026-01-28" version="50" xmlns="https://uniprot.org/uniprot">
    <accession>C1KRI5</accession>
    <name>C1KRI5_MICCC</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Small ribosomal subunit protein uS19c</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Small ribosomal subunit protein uS19m</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">rps19</name>
        <name evidence="9" type="ORF">MicpuN_mit70</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Micromonas commoda (strain RCC299 / NOUM17 / CCMP2709)</name>
        <name type="common">Picoplanktonic green alga</name>
        <dbReference type="NCBI Taxonomy" id="296587"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>Mamiellophyceae</taxon>
            <taxon>Mamiellales</taxon>
            <taxon>Mamiellaceae</taxon>
            <taxon>Micromonas</taxon>
        </lineage>
    </organism>
    <geneLocation type="mitochondrion" evidence="9"/>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2009-03" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Micromonas genome consortium"/>
                <person name="Robbens S."/>
                <person name="Rombauts S."/>
                <person name="Lucas S."/>
                <person name="Glavina del Rio T."/>
                <person name="Tice H."/>
                <person name="Bruce D."/>
                <person name="Pitluck S."/>
                <person name="Van de Peer Y."/>
                <person name="Zhou K."/>
                <person name="Grimwood J."/>
                <person name="Grigoriev I.V."/>
                <person name="Cuvelier M.L."/>
                <person name="Worden A.Z."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">RCC299 / NOUM17</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2009-04" db="EMBL/GenBank/DDBJ databases">
            <title>Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.</title>
            <authorList>
                <person name="Worden A.Z."/>
                <person name="Lee J.-H."/>
                <person name="Mock T."/>
                <person name="Rouze P."/>
                <person name="Simmons M.P."/>
                <person name="Aerts A.L."/>
                <person name="Allen A.E."/>
                <person name="Cuvelier M.L."/>
                <person name="Derelle E."/>
                <person name="Everett M.V."/>
                <person name="Foulon E."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Henrissat B."/>
                <person name="Napoli C."/>
                <person name="McDonald S.M."/>
                <person name="Schnitzler Parker M."/>
                <person name="Rombauts S."/>
                <person name="Salamov A."/>
                <person name="Von Dassow P."/>
                <person name="Badger J.H."/>
                <person name="Coutinho P.M."/>
                <person name="Demir E."/>
                <person name="Dubchak I."/>
                <person name="Gentemann C."/>
                <person name="Eikrem W."/>
                <person name="Gready J.E."/>
                <person name="John U."/>
                <person name="Lanier W."/>
                <person name="Lindquist E.A."/>
                <person name="Lucas S."/>
                <person name="Mayer K.F.X."/>
                <person name="Moreau H."/>
                <person name="Not F."/>
                <person name="Otillar R."/>
                <person name="Panaud O."/>
                <person name="Pangilinan J."/>
                <person name="Paulsen I."/>
                <person name="Piegu B."/>
                <person name="Poliakov A."/>
                <person name="Robbens S."/>
                <person name="Schmutz J."/>
                <person name="Toulza E."/>
                <person name="Wyss T."/>
                <person name="Zelensky A."/>
                <person name="Zhou K."/>
                <person name="Armbrust E.V."/>
                <person name="Bhattacharya D."/>
                <person name="Goodenough U.W."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">RCC299 / NOUM17</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the universal ribosomal protein uS19 family.</text>
    </comment>
    <dbReference type="EMBL" id="FJ859351">
        <property type="protein sequence ID" value="ACO55617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_002860153.1">
        <property type="nucleotide sequence ID" value="NC_012643.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="C1KRI5"/>
    <dbReference type="GeneID" id="7804382"/>
    <dbReference type="KEGG" id="mis:MicpuN_mit70"/>
    <dbReference type="OMA" id="YVAFEIT"/>
    <dbReference type="OrthoDB" id="565652at2759"/>
    <dbReference type="Proteomes" id="UP000002009">
        <property type="component" value="Mitochondrion MT"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.860.10:FF:000001">
        <property type="entry name" value="30S ribosomal protein S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.860.10">
        <property type="entry name" value="30s Ribosomal Protein S19, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00531">
        <property type="entry name" value="Ribosomal_uS19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002222">
        <property type="entry name" value="Ribosomal_uS19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005732">
        <property type="entry name" value="Ribosomal_uS19_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020934">
        <property type="entry name" value="Ribosomal_uS19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023575">
        <property type="entry name" value="Ribosomal_uS19_SF"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01050">
        <property type="entry name" value="rpsS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880">
        <property type="entry name" value="RIBOSOMAL PROTEIN S19P FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880:SF67">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US19M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00203">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002144">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00975">
        <property type="entry name" value="RIBOSOMALS19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54570">
        <property type="entry name" value="Ribosomal protein S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00323">
        <property type="entry name" value="RIBOSOMAL_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 8 9" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACO55617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000002009"/>
        </source>
    </evidence>
    <sequence length="84" mass="9944" checksum="12B71B636EA26974" modified="2009-05-26" version="1">MTRSVWKGPFVDVSVLQQSFDKRINIWSRRSVIIPQFINQQVYIYNGKTFVSLLVTEDMVGHKFGEFAMTRKRALHKKKVKKKK</sequence>
</entry>
<copyright>
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms Distributed under the Creative Commons Attribution (CC BY 4.0) License
</copyright>
</uniprot>