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<entry dataset="TrEMBL" created="2010-08-10" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>D7KI52</accession>
    <name>D7KI52_ARALL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Jacalin lectin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ARALYDRAFT_472198</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Arabidopsis lyrata subsp. lyrata</name>
        <name type="common">Lyre-leaved rock-cress</name>
        <dbReference type="NCBI Taxonomy" id="81972"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Tracheophyta</taxon>
            <taxon>Spermatophyta</taxon>
            <taxon>Magnoliopsida</taxon>
            <taxon>eudicotyledons</taxon>
            <taxon>Gunneridae</taxon>
            <taxon>Pentapetalae</taxon>
            <taxon>rosids</taxon>
            <taxon>malvids</taxon>
            <taxon>Brassicales</taxon>
            <taxon>Brassicaceae</taxon>
            <taxon>Camelineae</taxon>
            <taxon>Arabidopsis</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2011" name="Nat. Genet." volume="43" first="476" last="481">
            <title>The Arabidopsis lyrata genome sequence and the basis of rapid genome size change.</title>
            <authorList>
                <person name="Hu T.T."/>
                <person name="Pattyn P."/>
                <person name="Bakker E.G."/>
                <person name="Cao J."/>
                <person name="Cheng J.-F."/>
                <person name="Clark R.M."/>
                <person name="Fahlgren N."/>
                <person name="Fawcett J.A."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Haberer G."/>
                <person name="Hollister J.D."/>
                <person name="Ossowski S."/>
                <person name="Ottilar R.P."/>
                <person name="Salamov A.A."/>
                <person name="Schneeberger K."/>
                <person name="Spannagl M."/>
                <person name="Wang X."/>
                <person name="Yang L."/>
                <person name="Nasrallah M.E."/>
                <person name="Bergelson J."/>
                <person name="Carrington J.C."/>
                <person name="Gaut B.S."/>
                <person name="Schmutz J."/>
                <person name="Mayer K.F.X."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
                <person name="Nordborg M."/>
                <person name="Weigel D."/>
                <person name="Guo Y.-L."/>
            </authorList>
            <dbReference type="PubMed" id="21478890"/>
            <dbReference type="DOI" id="10.1038/ng.807"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">cv. MN47</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the jacalin lectin family.</text>
    </comment>
    <dbReference type="EMBL" id="GL348713">
        <property type="protein sequence ID" value="EFH69322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="AlphaFoldDB" id="D7KI52"/>
    <dbReference type="Gramene" id="fgenesh2_kg.1__2152__AT1G19715.1">
        <property type="protein sequence ID" value="fgenesh2_kg.1__2152__AT1G19715.1"/>
        <property type="gene ID" value="fgenesh2_kg.1__2152__AT1G19715.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019384_2_1_1"/>
    <dbReference type="Proteomes" id="UP000008694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="ExpressionAtlas" id="D7KI52">
        <property type="expression patterns" value="baseline"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09612">
        <property type="entry name" value="Jacalin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="FunFam" id="2.100.10.30:FF:000001">
        <property type="entry name" value="Jacalin-related lectin 33"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.100.10.30">
        <property type="entry name" value="Jacalin-like lectin domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001229">
        <property type="entry name" value="Jacalin-like_lectin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033734">
        <property type="entry name" value="Jacalin-like_lectin_dom_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036404">
        <property type="entry name" value="Jacalin-like_lectin_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47293">
        <property type="entry name" value="JACALIN-RELATED LECTIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47293:SF68">
        <property type="entry name" value="JACALIN-RELATED LECTIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01419">
        <property type="entry name" value="Jacalin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00915">
        <property type="entry name" value="Jacalin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51101">
        <property type="entry name" value="Mannose-binding lectins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51752">
        <property type="entry name" value="JACALIN_LECTIN"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0430">Lectin</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Jacalin-type lectin" evidence="3">
        <location>
            <begin position="7"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Jacalin-type lectin" evidence="3">
        <location>
            <begin position="234"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="Jacalin-type lectin" evidence="3">
        <location>
            <begin position="432"/>
            <end position="577"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFH69322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008694"/>
        </source>
    </evidence>
    <sequence length="596" mass="64880" checksum="66FBCB6AAC29784F" modified="2010-08-10" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-08-10" modified="2026-01-28" version="69" xmlns="https://uniprot.org/uniprot">
    <accession>D7KNA5</accession>
    <name>D7KNA5_ARALL</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ARALYDRAFT_888542</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Arabidopsis lyrata subsp. lyrata</name>
        <name type="common">Lyre-leaved rock-cress</name>
        <dbReference type="NCBI Taxonomy" id="81972"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Tracheophyta</taxon>
            <taxon>Spermatophyta</taxon>
            <taxon>Magnoliopsida</taxon>
            <taxon>eudicotyledons</taxon>
            <taxon>Gunneridae</taxon>
            <taxon>Pentapetalae</taxon>
            <taxon>rosids</taxon>
            <taxon>malvids</taxon>
            <taxon>Brassicales</taxon>
            <taxon>Brassicaceae</taxon>
            <taxon>Camelineae</taxon>
            <taxon>Arabidopsis</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2011" name="Nat. Genet." volume="43" first="476" last="481">
            <title>The Arabidopsis lyrata genome sequence and the basis of rapid genome size change.</title>
            <authorList>
                <person name="Hu T.T."/>
                <person name="Pattyn P."/>
                <person name="Bakker E.G."/>
                <person name="Cao J."/>
                <person name="Cheng J.-F."/>
                <person name="Clark R.M."/>
                <person name="Fahlgren N."/>
                <person name="Fawcett J.A."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Haberer G."/>
                <person name="Hollister J.D."/>
                <person name="Ossowski S."/>
                <person name="Ottilar R.P."/>
                <person name="Salamov A.A."/>
                <person name="Schneeberger K."/>
                <person name="Spannagl M."/>
                <person name="Wang X."/>
                <person name="Yang L."/>
                <person name="Nasrallah M.E."/>
                <person name="Bergelson J."/>
                <person name="Carrington J.C."/>
                <person name="Gaut B.S."/>
                <person name="Schmutz J."/>
                <person name="Mayer K.F.X."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
                <person name="Nordborg M."/>
                <person name="Weigel D."/>
                <person name="Guo Y.-L."/>
            </authorList>
            <dbReference type="PubMed" id="21478890"/>
            <dbReference type="DOI" id="10.1038/ng.807"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">cv. MN47</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the disease resistance NB-LRR family.</text>
    </comment>
    <dbReference type="EMBL" id="GL348713">
        <property type="protein sequence ID" value="EFH66180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="D7KNA5"/>
    <dbReference type="Gramene" id="scaffold_101336.1">
        <property type="protein sequence ID" value="scaffold_101336.1"/>
        <property type="gene ID" value="scaffold_101336.1"/>
    </dbReference>
    <dbReference type="KEGG" id="aly:110224135"/>
    <dbReference type="eggNOG" id="KOG4658">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000427_4_0_1"/>
    <dbReference type="OrthoDB" id="664960at2759"/>
    <dbReference type="Proteomes" id="UP000008694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001091">
        <property type="entry name" value="Probable disease resistance protein At1g61300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000322">
        <property type="entry name" value="Probable disease resistance protein At1g63360"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.430:FF:000003">
        <property type="entry name" value="Probable disease resistance protein At5g66910"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.430">
        <property type="entry name" value="Helical domain of apoptotic protease-activating factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042197">
        <property type="entry name" value="Apaf_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050905">
        <property type="entry name" value="Plant_NBS-LRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058922">
        <property type="entry name" value="WHD_DRP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33463:SF220">
        <property type="entry name" value="NB-ARC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33463">
        <property type="entry name" value="NB-ARC DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23559">
        <property type="entry name" value="WHD_DRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0611">Plant defense</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="NB-ARC" evidence="7">
        <location>
            <begin position="161"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="Disease resistance protein winged helix" evidence="8">
        <location>
            <begin position="417"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="domain" description="Disease resistance R13L4/SHOC-2-like LRR" evidence="9">
        <location>
            <begin position="525"/>
            <end position="828"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF23559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF23598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFH66180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008694"/>
        </source>
    </evidence>
    <sequence length="883" mass="101146" checksum="3DDFB51F92425277" modified="2010-08-10" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-08-10" modified="2025-10-08" version="56" xmlns="https://uniprot.org/uniprot">
    <accession>D7KPG0</accession>
    <name>D7KPG0_ARALL</name>
    <protein>
        <submittedName>
            <fullName evidence="9">CYP71B29</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ARALYDRAFT_471462</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Arabidopsis lyrata subsp. lyrata</name>
        <name type="common">Lyre-leaved rock-cress</name>
        <dbReference type="NCBI Taxonomy" id="81972"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Tracheophyta</taxon>
            <taxon>Spermatophyta</taxon>
            <taxon>Magnoliopsida</taxon>
            <taxon>eudicotyledons</taxon>
            <taxon>Gunneridae</taxon>
            <taxon>Pentapetalae</taxon>
            <taxon>rosids</taxon>
            <taxon>malvids</taxon>
            <taxon>Brassicales</taxon>
            <taxon>Brassicaceae</taxon>
            <taxon>Camelineae</taxon>
            <taxon>Arabidopsis</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2009-11" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="US DOE Joint Genome Institute (JGI-PGF)"/>
                <person name="Ottilar R."/>
                <person name="Schmutz J."/>
                <person name="Salamov A."/>
                <person name="Cheng J.F."/>
                <person name="Lucas S."/>
                <person name="Pitluck S."/>
                <person name="Gundlach H."/>
                <person name="Guo Y."/>
                <person name="Haberer G."/>
                <person name="Nasrallah J."/>
                <person name="Mayer K.F.X."/>
                <person name="van de Peer Y."/>
                <person name="Weigel D."/>
                <person name="Grigoriev I.V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2010-06" db="EMBL/GenBank/DDBJ databases">
            <title>The basis of rapid genome size change in Arabidopsis.</title>
            <authorList>
                <consortium name="US DOE Joint Genome Institute (JGI-PGF)"/>
                <person name="Bakker E."/>
                <person name="Bergelson J."/>
                <person name="Cheng J.Fang."/>
                <person name="Clark R.M."/>
                <person name="Fawcett J."/>
                <person name="Gaut B."/>
                <person name="Grigoriev I."/>
                <person name="Gundlach H."/>
                <person name="Guo Y."/>
                <person name="Haberer G."/>
                <person name="Hollister J."/>
                <person name="Hu T.T."/>
                <person name="Mayer K.F.X."/>
                <person name="Nasrallah J."/>
                <person name="Nordborg M."/>
                <person name="Otillar R."/>
                <person name="Pattyn P."/>
                <person name="Schmutz J."/>
                <person name="Spannagl M."/>
                <person name="van de Peer Y."/>
                <person name="Wang X."/>
                <person name="Weigel D."/>
                <person name="Yang L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="GL348713">
        <property type="protein sequence ID" value="EFH66246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="D7KPG0"/>
    <dbReference type="Gramene" id="fgenesh1_pg.C_scaffold_1001177">
        <property type="protein sequence ID" value="fgenesh1_pg.C_scaffold_1001177"/>
        <property type="gene ID" value="fgenesh1_pg.C_scaffold_1001177"/>
    </dbReference>
    <dbReference type="KEGG" id="aly:9326049"/>
    <dbReference type="eggNOG" id="KOG0156">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_4_1_1"/>
    <dbReference type="OrthoDB" id="1055148at2759"/>
    <dbReference type="Proteomes" id="UP000008694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11072">
        <property type="entry name" value="CYP71-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000011">
        <property type="entry name" value="Cytochrome P450 83B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050193">
        <property type="entry name" value="Cytochrome_P450_71"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47956">
        <property type="entry name" value="CYTOCHROME P450 71B11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47956:SF97">
        <property type="entry name" value="CYTOCHROME P450 71B29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0349">Heme</keyword>
    <keyword evidence="7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="440"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="EFH66246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008694"/>
        </source>
    </evidence>
    <sequence length="490" mass="56187" checksum="29F6F6D14A46FD2D" modified="2010-08-10" version="1">MVFFLCFLFLLPLIFIFLKIFKPSKYKWKLPPGPPKLPIIGNLHQLQELPPRNLSHKYGPVMLLRFGFVPVVVISSKEAAEEVLKIHDLECCSRPETAGTRKISYNFKDIGFAPYGEEWKAMRKLSVVELFNAKKHQYFRSIREEENDLLVKTLTELALTRSPVNLKKTLFTLVGSIVCRIGFGLNLHECEFIDEDSISDLVDKSEILEMTSMFSDFFPGGIGRFIDWISGQNKRFNNVFSDLDTFFENILNDHLKPGIVESSDIIDGMINMMKKQERDGDSFKLTTDHLKGMISDIFIAGVSTSASTLIWAITELVRNPKVMKKVQDEIRTTLGDKKERITEQDLTKLHYFKLVVKEIFRLHPAVPFLLPRETLSHVKIQGYDIPAKTQIMINVYAIARDPELWINPDEFNPDRFLDSSIDYKGLNFELLPFGSGRRICPGMTMGITLVELALLNLLYFFDWGLPEKEEVDKIITDNEVALGLVQVLLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-08-10" modified="2026-01-28" version="71" xmlns="https://uniprot.org/uniprot">
    <accession>D7KRC3</accession>
    <name>D7KRC3_ARALL</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">DNA-directed RNA polymerase subunit</fullName>
            <ecNumber evidence="13">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">ARALYDRAFT_893971</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Arabidopsis lyrata subsp. lyrata</name>
        <name type="common">Lyre-leaved rock-cress</name>
        <dbReference type="NCBI Taxonomy" id="81972"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Tracheophyta</taxon>
            <taxon>Spermatophyta</taxon>
            <taxon>Magnoliopsida</taxon>
            <taxon>eudicotyledons</taxon>
            <taxon>Gunneridae</taxon>
            <taxon>Pentapetalae</taxon>
            <taxon>rosids</taxon>
            <taxon>malvids</taxon>
            <taxon>Brassicales</taxon>
            <taxon>Brassicaceae</taxon>
            <taxon>Camelineae</taxon>
            <taxon>Arabidopsis</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2011" name="Nat. Genet." volume="43" first="476" last="481">
            <title>The Arabidopsis lyrata genome sequence and the basis of rapid genome size change.</title>
            <authorList>
                <person name="Hu T.T."/>
                <person name="Pattyn P."/>
                <person name="Bakker E.G."/>
                <person name="Cao J."/>
                <person name="Cheng J.-F."/>
                <person name="Clark R.M."/>
                <person name="Fahlgren N."/>
                <person name="Fawcett J.A."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Haberer G."/>
                <person name="Hollister J.D."/>
                <person name="Ossowski S."/>
                <person name="Ottilar R.P."/>
                <person name="Salamov A.A."/>
                <person name="Schneeberger K."/>
                <person name="Spannagl M."/>
                <person name="Wang X."/>
                <person name="Yang L."/>
                <person name="Nasrallah M.E."/>
                <person name="Bergelson J."/>
                <person name="Carrington J.C."/>
                <person name="Gaut B.S."/>
                <person name="Schmutz J."/>
                <person name="Mayer K.F.X."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
                <person name="Nordborg M."/>
                <person name="Weigel D."/>
                <person name="Guo Y.-L."/>
            </authorList>
            <dbReference type="PubMed" id="21478890"/>
            <dbReference type="DOI" id="10.1038/ng.807"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">cv. MN47</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 13">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="13"/>
    <dbReference type="EMBL" id="GL348714">
        <property type="protein sequence ID" value="EFH63123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="D7KRC3"/>
    <dbReference type="Gramene" id="fgenesh1_pm.C_scaffold_2000558">
        <property type="protein sequence ID" value="fgenesh1_pm.C_scaffold_2000558"/>
        <property type="gene ID" value="fgenesh1_pm.C_scaffold_2000558"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502QPYA">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030022_2_0_1"/>
    <dbReference type="Proteomes" id="UP000008694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.274.100:FF:000018">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.40.90:FF:000002">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.860.120:FF:000007">
        <property type="entry name" value="DNA-directed RNA polymerase subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.120">
        <property type="entry name" value="RNA polymerase II, clamp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.100">
        <property type="entry name" value="RNA polymerase Rpb1, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01323">
        <property type="entry name" value="RNApol_bact_RpoC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045867">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000722">
        <property type="entry name" value="RNA_pol_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006592">
        <property type="entry name" value="RNA_pol_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007080">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042102">
        <property type="entry name" value="RNA_pol_Rpb1_3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044893">
        <property type="entry name" value="RNA_pol_Rpb1_clamp_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034678">
        <property type="entry name" value="RNApol_RpoC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376:SF54">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04997">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00623">
        <property type="entry name" value="RNA_pol_Rpb1_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00663">
        <property type="entry name" value="RPOLA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="3 13" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5" id="KW-0934">Plastid</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 13" id="KW-0804">Transcription</keyword>
    <keyword evidence="6 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="RNA polymerase N-terminal" evidence="14">
        <location>
            <begin position="258"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EFH63123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000008694"/>
        </source>
    </evidence>
    <sequence length="676" mass="78088" checksum="12D2DBC051C7B0F1" modified="2010-08-10" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-08-10" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>D7KX05</accession>
    <name>D7KX05_ARALL</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Appr-1-p processing enzyme family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ARALYDRAFT_476061</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Arabidopsis lyrata subsp. lyrata</name>
        <name type="common">Lyre-leaved rock-cress</name>
        <dbReference type="NCBI Taxonomy" id="81972"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Tracheophyta</taxon>
            <taxon>Spermatophyta</taxon>
            <taxon>Magnoliopsida</taxon>
            <taxon>eudicotyledons</taxon>
            <taxon>Gunneridae</taxon>
            <taxon>Pentapetalae</taxon>
            <taxon>rosids</taxon>
            <taxon>malvids</taxon>
            <taxon>Brassicales</taxon>
            <taxon>Brassicaceae</taxon>
            <taxon>Camelineae</taxon>
            <taxon>Arabidopsis</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2011" name="Nat. Genet." volume="43" first="476" last="481">
            <title>The Arabidopsis lyrata genome sequence and the basis of rapid genome size change.</title>
            <authorList>
                <person name="Hu T.T."/>
                <person name="Pattyn P."/>
                <person name="Bakker E.G."/>
                <person name="Cao J."/>
                <person name="Cheng J.-F."/>
                <person name="Clark R.M."/>
                <person name="Fahlgren N."/>
                <person name="Fawcett J.A."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Haberer G."/>
                <person name="Hollister J.D."/>
                <person name="Ossowski S."/>
                <person name="Ottilar R.P."/>
                <person name="Salamov A.A."/>
                <person name="Schneeberger K."/>
                <person name="Spannagl M."/>
                <person name="Wang X."/>
                <person name="Yang L."/>
                <person name="Nasrallah M.E."/>
                <person name="Bergelson J."/>
                <person name="Carrington J.C."/>
                <person name="Gaut B.S."/>
                <person name="Schmutz J."/>
                <person name="Mayer K.F.X."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
                <person name="Nordborg M."/>
                <person name="Weigel D."/>
                <person name="Guo Y.-L."/>
            </authorList>
            <dbReference type="PubMed" id="21478890"/>
            <dbReference type="DOI" id="10.1038/ng.807"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">cv. MN47</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GDAP2 family.</text>
    </comment>
    <dbReference type="EMBL" id="GL348714">
        <property type="protein sequence ID" value="EFH63488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="Gramene" id="fgenesh2_kg.2__1191__AT1G69340.1">
        <property type="protein sequence ID" value="fgenesh2_kg.2__1191__AT1G69340.1"/>
        <property type="gene ID" value="fgenesh2_kg.2__1191__AT1G69340.1"/>
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    <dbReference type="eggNOG" id="KOG2633">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026877_0_1_1"/>
    <dbReference type="OrthoDB" id="6077599at2759"/>
    <dbReference type="Proteomes" id="UP000008694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02905">
        <property type="entry name" value="Macro_GDAP2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="entry name" value="Leucine Aminopeptidase, subunit E, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002589">
        <property type="entry name" value="Macro_dom"/>
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    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035793">
        <property type="entry name" value="Macro_GDAP2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11106">
        <property type="entry name" value="GANGLIOSIDE INDUCED DIFFERENTIATION ASSOCIATED PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11106:SF72">
        <property type="entry name" value="GANGLIOSIDE-INDUCED DIFFERENTIATION-ASSOCIATED PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13716">
        <property type="entry name" value="CRAL_TRIO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Macro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00506">
        <property type="entry name" value="A1pp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
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    </dbReference>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="Macro domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51154">
        <property type="entry name" value="MACRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Macro" evidence="3">
        <location>
            <begin position="74"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="38"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="EFH63488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008694"/>
        </source>
    </evidence>
    <sequence length="562" mass="63140" checksum="549C7BA6622543C4" modified="2010-08-10" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-08-10" modified="2026-01-28" version="75" xmlns="https://uniprot.org/uniprot">
    <accession>D7L7U4</accession>
    <name>D7L7U4_ARALL</name>
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        <submittedName>
            <fullName evidence="12">RNA polymerase II transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">ARALYDRAFT_317739</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Arabidopsis lyrata subsp. lyrata</name>
        <name type="common">Lyre-leaved rock-cress</name>
        <dbReference type="NCBI Taxonomy" id="81972"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Tracheophyta</taxon>
            <taxon>Spermatophyta</taxon>
            <taxon>Magnoliopsida</taxon>
            <taxon>eudicotyledons</taxon>
            <taxon>Gunneridae</taxon>
            <taxon>Pentapetalae</taxon>
            <taxon>rosids</taxon>
            <taxon>malvids</taxon>
            <taxon>Brassicales</taxon>
            <taxon>Brassicaceae</taxon>
            <taxon>Camelineae</taxon>
            <taxon>Arabidopsis</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2011" name="Nat. Genet." volume="43" first="476" last="481">
            <title>The Arabidopsis lyrata genome sequence and the basis of rapid genome size change.</title>
            <authorList>
                <person name="Hu T.T."/>
                <person name="Pattyn P."/>
                <person name="Bakker E.G."/>
                <person name="Cao J."/>
                <person name="Cheng J.-F."/>
                <person name="Clark R.M."/>
                <person name="Fahlgren N."/>
                <person name="Fawcett J.A."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Haberer G."/>
                <person name="Hollister J.D."/>
                <person name="Ossowski S."/>
                <person name="Ottilar R.P."/>
                <person name="Salamov A.A."/>
                <person name="Schneeberger K."/>
                <person name="Spannagl M."/>
                <person name="Wang X."/>
                <person name="Yang L."/>
                <person name="Nasrallah M.E."/>
                <person name="Bergelson J."/>
                <person name="Carrington J.C."/>
                <person name="Gaut B.S."/>
                <person name="Schmutz J."/>
                <person name="Mayer K.F.X."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
                <person name="Nordborg M."/>
                <person name="Weigel D."/>
                <person name="Guo Y.-L."/>
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            <dbReference type="PubMed" id="21478890"/>
            <dbReference type="DOI" id="10.1038/ng.807"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">cv. MN47</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TFIIB family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="Gramene" id="fgenesh1_pm.C_scaffold_3000755">
        <property type="protein sequence ID" value="fgenesh1_pm.C_scaffold_3000755"/>
        <property type="gene ID" value="fgenesh1_pm.C_scaffold_3000755"/>
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010293_1_0_1"/>
    <dbReference type="OrthoDB" id="511529at2759"/>
    <dbReference type="Proteomes" id="UP000008694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000126">
        <property type="term" value="C:transcription factor TFIIIB complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097550">
        <property type="term" value="C:transcription preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000995">
        <property type="term" value="F:RNA polymerase III general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001006">
        <property type="term" value="F:RNA polymerase III type 3 promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
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        <property type="term" value="P:transcription preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20554">
        <property type="entry name" value="CYCLIN_TFIIIB90_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.650:FF:000002">
        <property type="entry name" value="Cyclin/Brf1-like TBP-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000007">
        <property type="entry name" value="Transcription factor IIIB 90 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000066">
        <property type="entry name" value="Transcription factor IIIB subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.650">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011665">
        <property type="entry name" value="BRF1_TBP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000812">
        <property type="entry name" value="TFIIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013150">
        <property type="entry name" value="TFIIB_cyclin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618:SF4">
        <property type="entry name" value="TRANSCRIPTION FACTOR IIIB 90 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07741">
        <property type="entry name" value="BRF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00382">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00685">
        <property type="entry name" value="TIFACTORIIB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0010">Activator</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Cyclin-like" evidence="11">
        <location>
            <begin position="76"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="11">
        <location>
            <begin position="178"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="376"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="462"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="519"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="376"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="393"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="462"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="488"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="528"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="554"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="584"/>
            <end position="600"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFH58874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008694"/>
        </source>
    </evidence>
    <sequence length="600" mass="67244" checksum="DA74A87267E155A1" modified="2010-08-10" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-08-10" modified="2026-01-28" version="62" xmlns="https://uniprot.org/uniprot">
    <accession>D7L9F6</accession>
    <name>D7L9F6_ARALL</name>
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        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
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        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">ARALYDRAFT_343373</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Arabidopsis lyrata subsp. lyrata</name>
        <name type="common">Lyre-leaved rock-cress</name>
        <dbReference type="NCBI Taxonomy" id="81972"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Tracheophyta</taxon>
            <taxon>Spermatophyta</taxon>
            <taxon>Magnoliopsida</taxon>
            <taxon>eudicotyledons</taxon>
            <taxon>Gunneridae</taxon>
            <taxon>Pentapetalae</taxon>
            <taxon>rosids</taxon>
            <taxon>malvids</taxon>
            <taxon>Brassicales</taxon>
            <taxon>Brassicaceae</taxon>
            <taxon>Camelineae</taxon>
            <taxon>Arabidopsis</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2011" name="Nat. Genet." volume="43" first="476" last="481">
            <title>The Arabidopsis lyrata genome sequence and the basis of rapid genome size change.</title>
            <authorList>
                <person name="Hu T.T."/>
                <person name="Pattyn P."/>
                <person name="Bakker E.G."/>
                <person name="Cao J."/>
                <person name="Cheng J.-F."/>
                <person name="Clark R.M."/>
                <person name="Fahlgren N."/>
                <person name="Fawcett J.A."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Haberer G."/>
                <person name="Hollister J.D."/>
                <person name="Ossowski S."/>
                <person name="Ottilar R.P."/>
                <person name="Salamov A.A."/>
                <person name="Schneeberger K."/>
                <person name="Spannagl M."/>
                <person name="Wang X."/>
                <person name="Yang L."/>
                <person name="Nasrallah M.E."/>
                <person name="Bergelson J."/>
                <person name="Carrington J.C."/>
                <person name="Gaut B.S."/>
                <person name="Schmutz J."/>
                <person name="Mayer K.F.X."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
                <person name="Nordborg M."/>
                <person name="Weigel D."/>
                <person name="Guo Y.-L."/>
            </authorList>
            <dbReference type="PubMed" id="21478890"/>
            <dbReference type="DOI" id="10.1038/ng.807"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">cv. MN47</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the protein kinase superfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="GL348715">
        <property type="protein sequence ID" value="EFH60325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="D7L9F6"/>
    <dbReference type="Gramene" id="fgenesh2_kg.3__3341__AT2G17530.1">
        <property type="protein sequence ID" value="fgenesh2_kg.3__3341__AT2G17530.1"/>
        <property type="gene ID" value="fgenesh2_kg.3__3341__AT2G17530.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_81_13_1"/>
    <dbReference type="OrthoDB" id="2649at2759"/>
    <dbReference type="Proteomes" id="UP000008694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050684">
        <property type="term" value="P:regulation of mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000245">
        <property type="term" value="P:spliceosomal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14136">
        <property type="entry name" value="STKc_SRPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000303">
        <property type="entry name" value="Protein kinase superfamily protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000425">
        <property type="entry name" value="Serine/threonine-protein kinase SRPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051334">
        <property type="entry name" value="SRPK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634:SF5">
        <property type="entry name" value="OS09G0552300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="38"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="EFH60325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000008694"/>
        </source>
    </evidence>
    <sequence length="440" mass="49657" checksum="BDBCC1B666D539C6" modified="2010-08-10" version="1">MSCSSSSGSDEDDEGFDAYRKGGYHAVRIGDQFAGGRYIAQRKLGWGQFSTVWLAYDTRTSNYVALKIQKSALQFAQAALHEIELLQAAADGDPGNTKCVVRLIDDFKHAGPNGQHLCMVLEFLGDSLLRLIKYNRYKGMELSKVREICKCILTGLDYLHRELGMIHSDLKPENILLCSTIDPAKDPIRSGLTPILEKPEGNQNGTSTMNLIEKKLKRRAKKAAAKISGRRVSIVGLSETPTKNKRNLDGIDMRCKVVDFGNGCWADKKFAEEIQTRQYRAPEVILQSGYSYSVDMWSFACTAFELATGDMLFAPKEGNGYGEDEDHLALMMELLGKMPRKIAIGGARSKDYFDRHGDLKRIRRLKYWPLDRLLIDKYKLPEAESREFAEFLCPIMDFAPEKRPTAQQCLQHPWLNLRTQNNEDQIEGQMSNMQIKGSCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-08-10" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>D7LHR3</accession>
    <name>D7LHR3_ARALL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="4">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">ARALYDRAFT_902595</name>
    </gene>
    <organism evidence="20">
        <name type="scientific">Arabidopsis lyrata subsp. lyrata</name>
        <name type="common">Lyre-leaved rock-cress</name>
        <dbReference type="NCBI Taxonomy" id="81972"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Tracheophyta</taxon>
            <taxon>Spermatophyta</taxon>
            <taxon>Magnoliopsida</taxon>
            <taxon>eudicotyledons</taxon>
            <taxon>Gunneridae</taxon>
            <taxon>Pentapetalae</taxon>
            <taxon>rosids</taxon>
            <taxon>malvids</taxon>
            <taxon>Brassicales</taxon>
            <taxon>Brassicaceae</taxon>
            <taxon>Camelineae</taxon>
            <taxon>Arabidopsis</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2011" name="Nat. Genet." volume="43" first="476" last="481">
            <title>The Arabidopsis lyrata genome sequence and the basis of rapid genome size change.</title>
            <authorList>
                <person name="Hu T.T."/>
                <person name="Pattyn P."/>
                <person name="Bakker E.G."/>
                <person name="Cao J."/>
                <person name="Cheng J.-F."/>
                <person name="Clark R.M."/>
                <person name="Fahlgren N."/>
                <person name="Fawcett J.A."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Haberer G."/>
                <person name="Hollister J.D."/>
                <person name="Ossowski S."/>
                <person name="Ottilar R.P."/>
                <person name="Salamov A.A."/>
                <person name="Schneeberger K."/>
                <person name="Spannagl M."/>
                <person name="Wang X."/>
                <person name="Yang L."/>
                <person name="Nasrallah M.E."/>
                <person name="Bergelson J."/>
                <person name="Carrington J.C."/>
                <person name="Gaut B.S."/>
                <person name="Schmutz J."/>
                <person name="Mayer K.F.X."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
                <person name="Nordborg M."/>
                <person name="Weigel D."/>
                <person name="Guo Y.-L."/>
            </authorList>
            <dbReference type="PubMed" id="21478890"/>
            <dbReference type="DOI" id="10.1038/ng.807"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">cv. MN47</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the RING-type zinc finger family. ATL subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="4"/>
    <dbReference type="EMBL" id="GL348716">
        <property type="protein sequence ID" value="EFH57628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="D7LHR3"/>
    <dbReference type="Gramene" id="Al_scaffold_0004_1992">
        <property type="protein sequence ID" value="Al_scaffold_0004_1992"/>
        <property type="gene ID" value="Al_scaffold_0004_1992"/>
    </dbReference>
    <dbReference type="KEGG" id="aly:110224126"/>
    <dbReference type="eggNOG" id="KOG0800">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035191_1_0_1"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000008694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16461">
        <property type="entry name" value="RING-H2_EL5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000187">
        <property type="entry name" value="E3 ubiquitin-protein ligase ATL6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044600">
        <property type="entry name" value="ATL1/ATL16-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46913">
        <property type="entry name" value="RING-H2 FINGER PROTEIN ATL16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46913:SF1">
        <property type="entry name" value="RING-H2 FINGER PROTEIN ATL16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="17" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="8 14" id="KW-0863">Zinc-finger</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005672077" description="RING-type E3 ubiquitin transferase" evidence="17">
        <location>
            <begin position="34"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="18">
        <location>
            <begin position="134"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="186"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="349"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="192"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="363"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00024209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EFH57628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000008694"/>
        </source>
    </evidence>
    <sequence length="377" mass="41691" checksum="E82826C84378ED2C" modified="2010-08-10" version="1">MAIIDTNSSRWIPHNLLFLLLLLLLQSVPYGSGQTTPPGTTQTKANDPIVVVITVMFVVIFFMVFGSIFCRRSNARFYSRSSVFRSTDADAESRVVRIRRSTARGLEAEAIESFPTFLYSEVKAVRIGKGGVECAVCLCEFEDDETLRLMPPCCHVFHVDCVDVWLSEHSTCPLCRADLVLSQHGDDDDSTESYSGTDPGTISSGTDPERGMVLESSDAHLLDGVTWTNSNITPRSKSTGLSSWRITGILFPRSHSTGHSLVQPAGNLDRFTLTLPDDVRRQLMKTSRTMGHVALLPQARSSRSGYRSGSVGSERSVFTYGRKSNNNNRRLHSLSFSFSFRSGSVRSTFSGDAPKNLPTSVEAGERSFERLRPDDRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-08-10" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>D7LWX1</accession>
    <name>D7LWX1_ARALL</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cystatin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ARALYDRAFT_661552</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Arabidopsis lyrata subsp. lyrata</name>
        <name type="common">Lyre-leaved rock-cress</name>
        <dbReference type="NCBI Taxonomy" id="81972"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Tracheophyta</taxon>
            <taxon>Spermatophyta</taxon>
            <taxon>Magnoliopsida</taxon>
            <taxon>eudicotyledons</taxon>
            <taxon>Gunneridae</taxon>
            <taxon>Pentapetalae</taxon>
            <taxon>rosids</taxon>
            <taxon>malvids</taxon>
            <taxon>Brassicales</taxon>
            <taxon>Brassicaceae</taxon>
            <taxon>Camelineae</taxon>
            <taxon>Arabidopsis</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2011" name="Nat. Genet." volume="43" first="476" last="481">
            <title>The Arabidopsis lyrata genome sequence and the basis of rapid genome size change.</title>
            <authorList>
                <person name="Hu T.T."/>
                <person name="Pattyn P."/>
                <person name="Bakker E.G."/>
                <person name="Cao J."/>
                <person name="Cheng J.-F."/>
                <person name="Clark R.M."/>
                <person name="Fahlgren N."/>
                <person name="Fawcett J.A."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Haberer G."/>
                <person name="Hollister J.D."/>
                <person name="Ossowski S."/>
                <person name="Ottilar R.P."/>
                <person name="Salamov A.A."/>
                <person name="Schneeberger K."/>
                <person name="Spannagl M."/>
                <person name="Wang X."/>
                <person name="Yang L."/>
                <person name="Nasrallah M.E."/>
                <person name="Bergelson J."/>
                <person name="Carrington J.C."/>
                <person name="Gaut B.S."/>
                <person name="Schmutz J."/>
                <person name="Mayer K.F.X."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
                <person name="Nordborg M."/>
                <person name="Weigel D."/>
                <person name="Guo Y.-L."/>
            </authorList>
            <dbReference type="PubMed" id="21478890"/>
            <dbReference type="DOI" id="10.1038/ng.807"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">cv. MN47</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GL348718">
        <property type="protein sequence ID" value="EFH50070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="D7LWX1"/>
    <dbReference type="Gramene" id="fgenesh1_pm.C_scaffold_6001363">
        <property type="protein sequence ID" value="fgenesh1_pm.C_scaffold_6001363"/>
        <property type="gene ID" value="fgenesh1_pm.C_scaffold_6001363"/>
    </dbReference>
    <dbReference type="KEGG" id="aly:9307818"/>
    <dbReference type="HOGENOM" id="CLU_088056_2_0_1"/>
    <dbReference type="OrthoDB" id="1103804at2759"/>
    <dbReference type="Proteomes" id="UP000008694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006525">
        <property type="entry name" value="Cystatin-related_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046350">
        <property type="entry name" value="Cystatin_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01638">
        <property type="entry name" value="Atha_cystat_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31228">
        <property type="entry name" value="CYSTATIN/MONELLIN SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31228:SF40">
        <property type="entry name" value="CYSTATIN_MONELLIN SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54403">
        <property type="entry name" value="Cystatin/monellin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="EFH50070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008694"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="206" mass="23675" checksum="E8E2FBE94DFB8674" modified="2010-08-10" version="1">MTSANNELTCSTTGTSAKEEEVVSKVDKEDDESSSDSDGSDSEWAGYNWLPETEPEWDVDSFDGHEFKINPRVRKMYSSQELYDKYYNNRLKAFESKGFLPDHLNGIYNVYLDEKMDGYNTTRDFMVKLANVCVKKHNETKGTTLELVNVVRATERGAATWRFYITFMAQEYRDGPLVEYQAKVIKFLGDKVPFPVLCRPSPKPEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-08-10" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>D7M598</accession>
    <name>D7M598_ARALL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Auxin-responsive GH3 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ARALYDRAFT_909291</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Arabidopsis lyrata subsp. lyrata</name>
        <name type="common">Lyre-leaved rock-cress</name>
        <dbReference type="NCBI Taxonomy" id="81972"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Tracheophyta</taxon>
            <taxon>Spermatophyta</taxon>
            <taxon>Magnoliopsida</taxon>
            <taxon>eudicotyledons</taxon>
            <taxon>Gunneridae</taxon>
            <taxon>Pentapetalae</taxon>
            <taxon>rosids</taxon>
            <taxon>malvids</taxon>
            <taxon>Brassicales</taxon>
            <taxon>Brassicaceae</taxon>
            <taxon>Camelineae</taxon>
            <taxon>Arabidopsis</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2011" name="Nat. Genet." volume="43" first="476" last="481">
            <title>The Arabidopsis lyrata genome sequence and the basis of rapid genome size change.</title>
            <authorList>
                <person name="Hu T.T."/>
                <person name="Pattyn P."/>
                <person name="Bakker E.G."/>
                <person name="Cao J."/>
                <person name="Cheng J.-F."/>
                <person name="Clark R.M."/>
                <person name="Fahlgren N."/>
                <person name="Fawcett J.A."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Haberer G."/>
                <person name="Hollister J.D."/>
                <person name="Ossowski S."/>
                <person name="Ottilar R.P."/>
                <person name="Salamov A.A."/>
                <person name="Schneeberger K."/>
                <person name="Spannagl M."/>
                <person name="Wang X."/>
                <person name="Yang L."/>
                <person name="Nasrallah M.E."/>
                <person name="Bergelson J."/>
                <person name="Carrington J.C."/>
                <person name="Gaut B.S."/>
                <person name="Schmutz J."/>
                <person name="Mayer K.F.X."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
                <person name="Nordborg M."/>
                <person name="Weigel D."/>
                <person name="Guo Y.-L."/>
            </authorList>
            <dbReference type="PubMed" id="21478890"/>
            <dbReference type="DOI" id="10.1038/ng.807"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">cv. MN47</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IAA-amido conjugating enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="GL348718">
        <property type="protein sequence ID" value="EFH47825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="D7M598"/>
    <dbReference type="Gramene" id="fgenesh2_kg.6__1291__AT5G13380.1">
        <property type="protein sequence ID" value="fgenesh2_kg.6__1291__AT5G13380.1"/>
        <property type="gene ID" value="fgenesh2_kg.6__1291__AT5G13380.1"/>
    </dbReference>
    <dbReference type="eggNOG" id="ENOG502QPMU">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016249_2_1_1"/>
    <dbReference type="Proteomes" id="UP000008694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016881">
        <property type="term" value="F:acid-amino acid ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004993">
        <property type="entry name" value="GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055378">
        <property type="entry name" value="GH3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055377">
        <property type="entry name" value="GH3_M"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31901:SF54">
        <property type="entry name" value="AUXIN-RESPONSIVE GH3 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31901">
        <property type="entry name" value="GH3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03321">
        <property type="entry name" value="GH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23572">
        <property type="entry name" value="GH3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23571">
        <property type="entry name" value="GH3_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH3 middle" evidence="3">
        <location>
            <begin position="335"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="GH3 C-terminal" evidence="4">
        <location>
            <begin position="430"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFH47825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008694"/>
        </source>
    </evidence>
    <sequence length="583" mass="65755" checksum="E4CEF1EF00271B9D" modified="2010-08-10" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-08-10" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>D7M8J8</accession>
    <name>D7M8J8_ARALL</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ARALYDRAFT_912407</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Arabidopsis lyrata subsp. lyrata</name>
        <name type="common">Lyre-leaved rock-cress</name>
        <dbReference type="NCBI Taxonomy" id="81972"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Tracheophyta</taxon>
            <taxon>Spermatophyta</taxon>
            <taxon>Magnoliopsida</taxon>
            <taxon>eudicotyledons</taxon>
            <taxon>Gunneridae</taxon>
            <taxon>Pentapetalae</taxon>
            <taxon>rosids</taxon>
            <taxon>malvids</taxon>
            <taxon>Brassicales</taxon>
            <taxon>Brassicaceae</taxon>
            <taxon>Camelineae</taxon>
            <taxon>Arabidopsis</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2011" name="Nat. Genet." volume="43" first="476" last="481">
            <title>The Arabidopsis lyrata genome sequence and the basis of rapid genome size change.</title>
            <authorList>
                <person name="Hu T.T."/>
                <person name="Pattyn P."/>
                <person name="Bakker E.G."/>
                <person name="Cao J."/>
                <person name="Cheng J.-F."/>
                <person name="Clark R.M."/>
                <person name="Fahlgren N."/>
                <person name="Fawcett J.A."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Haberer G."/>
                <person name="Hollister J.D."/>
                <person name="Ossowski S."/>
                <person name="Ottilar R.P."/>
                <person name="Salamov A.A."/>
                <person name="Schneeberger K."/>
                <person name="Spannagl M."/>
                <person name="Wang X."/>
                <person name="Yang L."/>
                <person name="Nasrallah M.E."/>
                <person name="Bergelson J."/>
                <person name="Carrington J.C."/>
                <person name="Gaut B.S."/>
                <person name="Schmutz J."/>
                <person name="Mayer K.F.X."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
                <person name="Nordborg M."/>
                <person name="Weigel D."/>
                <person name="Guo Y.-L."/>
            </authorList>
            <dbReference type="PubMed" id="21478890"/>
            <dbReference type="DOI" id="10.1038/ng.807"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">cv. MN47</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="GL348719">
        <property type="protein sequence ID" value="EFH43109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="D7M8J8"/>
    <dbReference type="Gramene" id="fgenesh2_kg.7__154__AT4G39430.1">
        <property type="protein sequence ID" value="fgenesh2_kg.7__154__AT4G39430.1"/>
        <property type="gene ID" value="fgenesh2_kg.7__154__AT4G39430.1"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG1884">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_632230_0_0_1"/>
    <dbReference type="Proteomes" id="UP000008694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028103">
        <property type="entry name" value="Spatacsin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13650">
        <property type="entry name" value="SPATACSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13650:SF0">
        <property type="entry name" value="SPATACSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="EFH43109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008694"/>
        </source>
    </evidence>
    <sequence length="405" mass="45506" checksum="62A1614AE510DB4A" modified="2010-08-10" version="1" fragment="single">MLGNVKLAEEGMLRVLFSAVYLLSHKNRNDNQISAVSRLLGLATRFATEMIRIYGLLEYQKDGYMLDSKPRTQILSLPPVSLHIDVMENSRRLSEMGYLLEITRNFQSRITRKFKKLGKVLYDINTNGKNEKSLNLVDPNSLQDDSQLEIVPDPASAESRQLDTSLFDTNGELALTPMGMMTAKAGQIIGERSYASGLVPQVVVEEKKVLPLENPKEMMARWKANNLDLKTVVKDALLSGRLPLAVLQLHLQHSKDVVEDGEHHDTFTEVRDIGRAIAYDLFLKGEPGVAIATLQRLGEDVEACLNQLVFGTVRRSIRYQIAEEMRKLGFLRPYEDNVLERISLIEHLKLDCGEVDGVVLGSWTKINESASEHAPDETDAVAGYWAAAAVWSNAWDQRTFDHVRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-08-10" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>D7M8K5</accession>
    <name>D7M8K5_ARALL</name>
    <protein>
        <submittedName>
            <fullName evidence="11">CYP96A12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ARALYDRAFT_352944</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Arabidopsis lyrata subsp. lyrata</name>
        <name type="common">Lyre-leaved rock-cress</name>
        <dbReference type="NCBI Taxonomy" id="81972"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Tracheophyta</taxon>
            <taxon>Spermatophyta</taxon>
            <taxon>Magnoliopsida</taxon>
            <taxon>eudicotyledons</taxon>
            <taxon>Gunneridae</taxon>
            <taxon>Pentapetalae</taxon>
            <taxon>rosids</taxon>
            <taxon>malvids</taxon>
            <taxon>Brassicales</taxon>
            <taxon>Brassicaceae</taxon>
            <taxon>Camelineae</taxon>
            <taxon>Arabidopsis</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2011" name="Nat. Genet." volume="43" first="476" last="481">
            <title>The Arabidopsis lyrata genome sequence and the basis of rapid genome size change.</title>
            <authorList>
                <person name="Hu T.T."/>
                <person name="Pattyn P."/>
                <person name="Bakker E.G."/>
                <person name="Cao J."/>
                <person name="Cheng J.-F."/>
                <person name="Clark R.M."/>
                <person name="Fahlgren N."/>
                <person name="Fawcett J.A."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Haberer G."/>
                <person name="Hollister J.D."/>
                <person name="Ossowski S."/>
                <person name="Ottilar R.P."/>
                <person name="Salamov A.A."/>
                <person name="Schneeberger K."/>
                <person name="Spannagl M."/>
                <person name="Wang X."/>
                <person name="Yang L."/>
                <person name="Nasrallah M.E."/>
                <person name="Bergelson J."/>
                <person name="Carrington J.C."/>
                <person name="Gaut B.S."/>
                <person name="Schmutz J."/>
                <person name="Mayer K.F.X."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
                <person name="Nordborg M."/>
                <person name="Weigel D."/>
                <person name="Guo Y.-L."/>
            </authorList>
            <dbReference type="PubMed" id="21478890"/>
            <dbReference type="DOI" id="10.1038/ng.807"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">cv. MN47</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EMBL" id="GL348719">
        <property type="protein sequence ID" value="EFH45168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="D7M8K5"/>
    <dbReference type="Gramene" id="fgenesh2_kg.7__161__AT4G39510.1">
        <property type="protein sequence ID" value="fgenesh2_kg.7__161__AT4G39510.1"/>
        <property type="gene ID" value="fgenesh2_kg.7__161__AT4G39510.1"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0157">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_27_2_1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000008694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11064">
        <property type="entry name" value="CYP86A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24296">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="452"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="EFH45168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008694"/>
        </source>
    </evidence>
    <sequence length="507" mass="58273" checksum="A76BDE54B31AC7ED" modified="2010-08-10" version="1">MASISLLDASIAIICFLFFHFFIFKKPHDQVFRNWPVIGMIGFLMVLHRMYNFGVEALEISHLTFPFKGPWFAGMDMLFTVDPANIHYILSSNFSNYTKGADFKEVFDVFGEMIFSSDSELWKNQRKAAQFMLNHHEFQKLSMSATRTKLYDGLVPLFNQYCEEEKVVDLQQVFQRFTFDTTFFLVTGSDPKSLSIEMPEVEYAKALDDLGEGIFYRHIKPKFLWKLQNRFGLGQEKRMTEADATFDRVSAKYISAKREEIRSQGIDHHSNGQSEDLLTSHIKLDTTKYELLNPSDDKFLRDTILAFNLAGRDTMSSALSWFFWLLSENPQVVTKIRKEIISKNISKDGRNGQENLDKLVYLHAALYESMRLYPPVAFQRKSPIKPDLLPSGHKVDANSVIIIFLYGLGRMRAVWGEDATEFKPERWVSETGGLRHAPSFKFLSFNAGPRTCPGKQLAMTLMKTVVVEILQNYDIKVIKGQKIEPEPGLILHMKHGLKVTITKRCSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-08-10" modified="2026-01-28" version="63" xmlns="https://uniprot.org/uniprot">
    <accession>D7MJ85</accession>
    <name>D7MJ85_ARALL</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ARALYDRAFT_493946</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Arabidopsis lyrata subsp. lyrata</name>
        <name type="common">Lyre-leaved rock-cress</name>
        <dbReference type="NCBI Taxonomy" id="81972"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Tracheophyta</taxon>
            <taxon>Spermatophyta</taxon>
            <taxon>Magnoliopsida</taxon>
            <taxon>eudicotyledons</taxon>
            <taxon>Gunneridae</taxon>
            <taxon>Pentapetalae</taxon>
            <taxon>rosids</taxon>
            <taxon>malvids</taxon>
            <taxon>Brassicales</taxon>
            <taxon>Brassicaceae</taxon>
            <taxon>Camelineae</taxon>
            <taxon>Arabidopsis</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2011" name="Nat. Genet." volume="43" first="476" last="481">
            <title>The Arabidopsis lyrata genome sequence and the basis of rapid genome size change.</title>
            <authorList>
                <person name="Hu T.T."/>
                <person name="Pattyn P."/>
                <person name="Bakker E.G."/>
                <person name="Cao J."/>
                <person name="Cheng J.-F."/>
                <person name="Clark R.M."/>
                <person name="Fahlgren N."/>
                <person name="Fawcett J.A."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Haberer G."/>
                <person name="Hollister J.D."/>
                <person name="Ossowski S."/>
                <person name="Ottilar R.P."/>
                <person name="Salamov A.A."/>
                <person name="Schneeberger K."/>
                <person name="Spannagl M."/>
                <person name="Wang X."/>
                <person name="Yang L."/>
                <person name="Nasrallah M.E."/>
                <person name="Bergelson J."/>
                <person name="Carrington J.C."/>
                <person name="Gaut B.S."/>
                <person name="Schmutz J."/>
                <person name="Mayer K.F.X."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
                <person name="Nordborg M."/>
                <person name="Weigel D."/>
                <person name="Guo Y.-L."/>
            </authorList>
            <dbReference type="PubMed" id="21478890"/>
            <dbReference type="DOI" id="10.1038/ng.807"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">cv. MN47</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PPR family. PCMP-H subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="GL348719">
        <property type="protein sequence ID" value="EFH46966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="D7MJ85"/>
    <dbReference type="Gramene" id="fgenesh2_kg.7__3379__AT5G40410.1">
        <property type="protein sequence ID" value="fgenesh2_kg.7__3379__AT5G40410.1"/>
        <property type="gene ID" value="fgenesh2_kg.7__3379__AT5G40410.1"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG4197">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002706_37_1_1"/>
    <dbReference type="Proteomes" id="UP000008694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009451">
        <property type="term" value="P:RNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000475">
        <property type="entry name" value="Pentatricopeptide repeat-containing protein At5g40410, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000407">
        <property type="entry name" value="Putative pentatricopeptide repeat-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032867">
        <property type="entry name" value="DYW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046849">
        <property type="entry name" value="E2_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046848">
        <property type="entry name" value="E_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046960">
        <property type="entry name" value="PPR_At4g14850-like_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47926:SF533">
        <property type="entry name" value="DYW DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47926">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14432">
        <property type="entry name" value="DYW_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20431">
        <property type="entry name" value="E_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20430">
        <property type="entry name" value="Eplus_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="5"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="108"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="209"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="244"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="DYW" evidence="4">
        <location>
            <begin position="425"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="EFH46966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008694"/>
        </source>
    </evidence>
    <sequence length="517" mass="58488" checksum="677F004732E1DC35" modified="2010-08-10" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-08-10" modified="2026-01-28" version="86" xmlns="https://uniprot.org/uniprot">
    <accession>D7MKN0</accession>
    <name>D7MKN0_ARALL</name>
    <protein>
        <submittedName>
            <fullName evidence="19">Calnexin 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">ARALYDRAFT_496347</name>
    </gene>
    <organism evidence="20">
        <name type="scientific">Arabidopsis lyrata subsp. lyrata</name>
        <name type="common">Lyre-leaved rock-cress</name>
        <dbReference type="NCBI Taxonomy" id="81972"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Tracheophyta</taxon>
            <taxon>Spermatophyta</taxon>
            <taxon>Magnoliopsida</taxon>
            <taxon>eudicotyledons</taxon>
            <taxon>Gunneridae</taxon>
            <taxon>Pentapetalae</taxon>
            <taxon>rosids</taxon>
            <taxon>malvids</taxon>
            <taxon>Brassicales</taxon>
            <taxon>Brassicaceae</taxon>
            <taxon>Camelineae</taxon>
            <taxon>Arabidopsis</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2011" name="Nat. Genet." volume="43" first="476" last="481">
            <title>The Arabidopsis lyrata genome sequence and the basis of rapid genome size change.</title>
            <authorList>
                <person name="Hu T.T."/>
                <person name="Pattyn P."/>
                <person name="Bakker E.G."/>
                <person name="Cao J."/>
                <person name="Cheng J.-F."/>
                <person name="Clark R.M."/>
                <person name="Fahlgren N."/>
                <person name="Fawcett J.A."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Haberer G."/>
                <person name="Hollister J.D."/>
                <person name="Ossowski S."/>
                <person name="Ottilar R.P."/>
                <person name="Salamov A.A."/>
                <person name="Schneeberger K."/>
                <person name="Spannagl M."/>
                <person name="Wang X."/>
                <person name="Yang L."/>
                <person name="Nasrallah M.E."/>
                <person name="Bergelson J."/>
                <person name="Carrington J.C."/>
                <person name="Gaut B.S."/>
                <person name="Schmutz J."/>
                <person name="Mayer K.F.X."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
                <person name="Nordborg M."/>
                <person name="Weigel D."/>
                <person name="Guo Y.-L."/>
            </authorList>
            <dbReference type="PubMed" id="21478890"/>
            <dbReference type="DOI" id="10.1038/ng.807"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">cv. MN47</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Calcium-binding protein that interacts with newly synthesized monoglucosylated glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 17">Belongs to the calreticulin family.</text>
    </comment>
    <dbReference type="EMBL" id="GL348720">
        <property type="protein sequence ID" value="EFH42713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="D7MKN0"/>
    <dbReference type="Gramene" id="fgenesh2_kg.8__2163__AT5G61790.1">
        <property type="protein sequence ID" value="fgenesh2_kg.8__2163__AT5G61790.1"/>
        <property type="gene ID" value="fgenesh2_kg.8__2163__AT5G61790.1"/>
    </dbReference>
    <dbReference type="eggNOG" id="KOG0675">
        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018224_1_0_1"/>
    <dbReference type="OrthoDB" id="1938156at2759"/>
    <dbReference type="Proteomes" id="UP000008694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="term" value="F:carbohydrate binding"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="F:unfolded protein binding"/>
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        <property type="term" value="P:ERAD pathway"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="P:protein folding"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Calnexin homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.250.10">
        <property type="entry name" value="Calreticulin/calnexin, P domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001580">
        <property type="entry name" value="Calret/calnex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018124">
        <property type="entry name" value="Calret/calnex_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009033">
        <property type="entry name" value="Calreticulin/calnexin_P_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="CALNEXIN 14D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11073">
        <property type="entry name" value="CALRETICULIN AND CALNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00262">
        <property type="entry name" value="Calreticulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00626">
        <property type="entry name" value="CALRETICULIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63887">
        <property type="entry name" value="P-domain of calnexin/calreticulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00803">
        <property type="entry name" value="CALRETICULIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00804">
        <property type="entry name" value="CALRETICULIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00805">
        <property type="entry name" value="CALRETICULIN_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0106">Calcium</keyword>
    <keyword evidence="14 17" id="KW-0143">Chaperone</keyword>
    <keyword evidence="12 16" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8 17" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0430">Lectin</keyword>
    <keyword evidence="11 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 17" id="KW-0732">Signal</keyword>
    <keyword evidence="3 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 17" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005127019" evidence="17">
        <location>
            <begin position="26"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="465"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="216"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="490"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="224"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="18">
        <location>
            <begin position="250"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="492"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="18">
        <location>
            <begin position="520"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="16">
        <location>
            <begin position="108"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010983"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
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    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
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    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
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    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
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    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00037525"/>
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    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR601580-3"/>
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    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU362126"/>
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    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="EFH42713.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000008694"/>
        </source>
    </evidence>
    <sequence length="529" mass="60361" checksum="62E7955FF2DB612F" modified="2010-08-10" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2010-08-10" modified="2026-01-28" version="81" xmlns="https://uniprot.org/uniprot">
    <accession>D7MKN1</accession>
    <name>D7MKN1_ARALL</name>
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        <submittedName>
            <fullName evidence="15">Mitochondrial substrate carrier family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">ARALYDRAFT_496347</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Arabidopsis lyrata subsp. lyrata</name>
        <name type="common">Lyre-leaved rock-cress</name>
        <dbReference type="NCBI Taxonomy" id="81972"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Tracheophyta</taxon>
            <taxon>Spermatophyta</taxon>
            <taxon>Magnoliopsida</taxon>
            <taxon>eudicotyledons</taxon>
            <taxon>Gunneridae</taxon>
            <taxon>Pentapetalae</taxon>
            <taxon>rosids</taxon>
            <taxon>malvids</taxon>
            <taxon>Brassicales</taxon>
            <taxon>Brassicaceae</taxon>
            <taxon>Camelineae</taxon>
            <taxon>Arabidopsis</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2011" name="Nat. Genet." volume="43" first="476" last="481">
            <title>The Arabidopsis lyrata genome sequence and the basis of rapid genome size change.</title>
            <authorList>
                <person name="Hu T.T."/>
                <person name="Pattyn P."/>
                <person name="Bakker E.G."/>
                <person name="Cao J."/>
                <person name="Cheng J.-F."/>
                <person name="Clark R.M."/>
                <person name="Fahlgren N."/>
                <person name="Fawcett J.A."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Haberer G."/>
                <person name="Hollister J.D."/>
                <person name="Ossowski S."/>
                <person name="Ottilar R.P."/>
                <person name="Salamov A.A."/>
                <person name="Schneeberger K."/>
                <person name="Spannagl M."/>
                <person name="Wang X."/>
                <person name="Yang L."/>
                <person name="Nasrallah M.E."/>
                <person name="Bergelson J."/>
                <person name="Carrington J.C."/>
                <person name="Gaut B.S."/>
                <person name="Schmutz J."/>
                <person name="Mayer K.F.X."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
                <person name="Nordborg M."/>
                <person name="Weigel D."/>
                <person name="Guo Y.-L."/>
            </authorList>
            <dbReference type="PubMed" id="21478890"/>
            <dbReference type="DOI" id="10.1038/ng.807"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">cv. MN47</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
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        <property type="taxonomic scope" value="Eukaryota"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="270584at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:mitochondrial inner membrane"/>
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        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015217">
        <property type="term" value="F:ADP transmembrane transporter activity"/>
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        <property type="project" value="EnsemblPlants"/>
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    <dbReference type="GO" id="GO:0080122">
        <property type="term" value="F:AMP transmembrane transporter activity"/>
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        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005347">
        <property type="term" value="F:ATP transmembrane transporter activity"/>
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        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035435">
        <property type="term" value="P:phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
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        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
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        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24089">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13202">
        <property type="entry name" value="EF-hand_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 12 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 13" id="KW-0813">Transport</keyword>
    <feature type="domain" description="EF-hand" evidence="14">
        <location>
            <begin position="99"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="14">
        <location>
            <begin position="135"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="12">
        <location>
            <begin position="202"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="12">
        <location>
            <begin position="293"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="12">
        <location>
            <begin position="391"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="EFH42715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000008694"/>
        </source>
    </evidence>
    <sequence length="478" mass="53600" checksum="262D9A3E569AC8FA" modified="2010-08-10" version="1">MEAEKSKKNPVKKPVEATMEHVLVALRETKEERETRIRKLFEFFDNSKLGFLDDTQIEKGLSSLSIPQNYRYASDFLKVCDANRDGRVDYQEFRRYMDSKELELYKIFQAIDVEHNGDICPEELWEALDKAGIKIKDEELASFMEHVDKDNNGIITFEEWRDFLLLNPHEATIENIYHHWERVCLIDIGEQAVIPDGISTHAQRSKLLLAGGIAGAVSRTATAPLDRLKVALQVQRTNLGVVPTIKKIWREDKLLGFFRGNGLNVTKVAPESAIKFAAYEMLKSIIGGVDGDIGTSGRLLAGGLAGAVAQTAIYPMDLVKTRLQTFVSEVGTPKLWKLTKDIWIQEGPRAFYRGLCPSLIGIIPYAGIDLAAYETLKDLSRSHFLHDTAEPGPLIQLGCGMTSGALGASCVYPLQVIRTRMQADISKTSMIQEFLKTLRGEGLRGFYRGIFPNFFKVIPSASISYLVYEAMKKNLALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-08-10" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>D7MLC2</accession>
    <name>D7MLC2_ARALL</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">AT-hook motif nuclear-localized protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ARALYDRAFT_496402</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Arabidopsis lyrata subsp. lyrata</name>
        <name type="common">Lyre-leaved rock-cress</name>
        <dbReference type="NCBI Taxonomy" id="81972"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Tracheophyta</taxon>
            <taxon>Spermatophyta</taxon>
            <taxon>Magnoliopsida</taxon>
            <taxon>eudicotyledons</taxon>
            <taxon>Gunneridae</taxon>
            <taxon>Pentapetalae</taxon>
            <taxon>rosids</taxon>
            <taxon>malvids</taxon>
            <taxon>Brassicales</taxon>
            <taxon>Brassicaceae</taxon>
            <taxon>Camelineae</taxon>
            <taxon>Arabidopsis</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2011" name="Nat. Genet." volume="43" first="476" last="481">
            <title>The Arabidopsis lyrata genome sequence and the basis of rapid genome size change.</title>
            <authorList>
                <person name="Hu T.T."/>
                <person name="Pattyn P."/>
                <person name="Bakker E.G."/>
                <person name="Cao J."/>
                <person name="Cheng J.-F."/>
                <person name="Clark R.M."/>
                <person name="Fahlgren N."/>
                <person name="Fawcett J.A."/>
                <person name="Grimwood J."/>
                <person name="Gundlach H."/>
                <person name="Haberer G."/>
                <person name="Hollister J.D."/>
                <person name="Ossowski S."/>
                <person name="Ottilar R.P."/>
                <person name="Salamov A.A."/>
                <person name="Schneeberger K."/>
                <person name="Spannagl M."/>
                <person name="Wang X."/>
                <person name="Yang L."/>
                <person name="Nasrallah M.E."/>
                <person name="Bergelson J."/>
                <person name="Carrington J.C."/>
                <person name="Gaut B.S."/>
                <person name="Schmutz J."/>
                <person name="Mayer K.F.X."/>
                <person name="Van de Peer Y."/>
                <person name="Grigoriev I.V."/>
                <person name="Nordborg M."/>
                <person name="Weigel D."/>
                <person name="Guo Y.-L."/>
            </authorList>
            <dbReference type="PubMed" id="21478890"/>
            <dbReference type="DOI" id="10.1038/ng.807"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">cv. MN47</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Transcription factor that specifically binds AT-rich DNA sequences related to the nuclear matrix attachment regions (MARs).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="6">The PPC domain mediates interactions between AHL proteins.</text>
    </comment>
    <dbReference type="EMBL" id="GL348720">
        <property type="protein sequence ID" value="EFH41038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="D7MLC2"/>
    <dbReference type="Gramene" id="fgenesh2_kg.8__2218__AT5G62260.1">
        <property type="protein sequence ID" value="fgenesh2_kg.8__2218__AT5G62260.1"/>
        <property type="gene ID" value="fgenesh2_kg.8__2218__AT5G62260.1"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039808_0_0_1"/>
    <dbReference type="OrthoDB" id="2014829at2759"/>
    <dbReference type="Proteomes" id="UP000008694">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblPlants"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003680">
        <property type="term" value="F:minor groove of adenine-thymine-rich DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11378">
        <property type="entry name" value="DUF296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.80">
        <property type="entry name" value="Hypothetical protein, similar to alpha- acetolactate decarboxylase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039605">
        <property type="entry name" value="AHL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005175">
        <property type="entry name" value="PPC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31500:SF82">
        <property type="entry name" value="AT-HOOK MOTIF NUCLEAR-LOCALIZED PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31500">
        <property type="entry name" value="AT-HOOK MOTIF NUCLEAR-LOCALIZED PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03479">
        <property type="entry name" value="PCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117856">
        <property type="entry name" value="AF0104/ALDC/Ptd012-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51742">
        <property type="entry name" value="PPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="253"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="PPC" evidence="9">
        <location>
            <begin position="157"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="41"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="349"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="46"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="58"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="98"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="349"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="378"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="EFH41038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008694"/>
        </source>
    </evidence>
    <sequence length="399" mass="42308" checksum="13EA486B48E3EAB8" modified="2010-08-10" version="1">MEEKGGISPSGVVTVKEDEALVPRTEFQQNPSFLQFVSPTTVVSPLPLPPAPSPAPVPATVTPDSAAASTGSDPTKKKRGRPRKYAPDGSLNPRFSRPTLSPTPISSSIPLSGDYQWKRGKAQQQHQPLEFVKKSHKFEYGSPAPTPPPPGLSCYVGANFTTHQFTVNAGEDVTMKVMPYSQQGSRAICILSATGSISNVTLGQPTNAGGTLTYEGRFEILSLSGSFMPTENGGTKGRTGGMSISLAGPNGKIFGGGLAGMLIAAGPVQVVMGSFIVMHQAEQNQKKKPRVMEAFAPPPQQPPQLQQQQPPTFTITTVNSTSPATVEEPKQQPYGGGIVRPMAQMSSSFQNENSTMNNFTPPYHGYGNMNTGTNKDEHEDDDGGEDDDSGDTRSQSLSG</sequence>
</entry>
<copyright>
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms Distributed under the Creative Commons Attribution (CC BY 4.0) License
</copyright>
</uniprot>